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Sample records for exemption ide process

  1. 29 CFR 780.806 - Exempt ginning limited to first processing.

    Science.gov (United States)

    2010-07-01

    ... cottonseed, is not exempt under section 13(b)(15). It is not first processing of the seed cotton; rather, it... 29 Labor 3 2010-07-01 2010-07-01 false Exempt ginning limited to first processing. 780.806 Section... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT...

  2. 40 CFR 761.80 - Manufacturing, processing and distribution in commerce exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Manufacturing, processing and..., PROCESSING, DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS Exemptions § 761.80 Manufacturing, processing and... any change in the manner of processing and distributing, importing (manufacturing), or exporting of...

  3. IDE DAN DESAIN

    Directory of Open Access Journals (Sweden)

    Priscilia Yunita Wijaya

    1999-01-01

    Full Text Available We have seen many desain all around our everyday living. Design exist in the form of brochures%2C posters%2C banners%2C signages%2C book covers%2C and etcetera. Some are nice and easy to understand%2C some are ok%2C and some look like they are not fully develop and thought. A word that run across our mind whrn we enjoying a design is idea . A good design almost always associated with a good idea%2C is it tru? This paper is going to discuss about desain and its relationship to idea. Abstract in Bahasa Indonesia : Banyak desain yang diamati dalam kehidupan kita sehari-hari. Desain hadir dalam bentuk brosur%2C poster%2C spanduk%2C tanda-tanda%2C sampul buku%2C dan lain sebagainya. Ada beberapa yang bagus dan mudah untuk dimengerti%2C beberapa yang biasa%2C dan beberapa yang tampak asal dibuat. Sebuah kata yang terlintas dalam pemikiran kita dalam menikmati sebuah desain adalah ide . Sebuah desain yang baik selalu di identikan dengan ide yang baik%2C benarkah hal ini? Apakah desain dan apa hubungannya dengan ide akan dibahas pada tulisan ini.

  4. 10 CFR 490.204 - Process for granting exemptions.

    Science.gov (United States)

    2010-01-01

    ... year, or it may require a State to acquire all or some of the exempted vehicles in future model years...) Alternative fuels that meet the normal requirements and practices of the principal business of the State fleet... requirements and practices of the principal business of the State fleet are not available for purchase or lease...

  5. 10 CFR 490.308 - Process for granting exemptions.

    Science.gov (United States)

    2010-01-01

    ... require a covered person to acquire all or some of the exempted vehicles in future model years. (f) The... business unit which is subject to section 490.302 of this part, shall submit a written request for... the principal business of the covered person are not available from fueling sites that would permit...

  6. Redundant arrays of IDE drives

    Energy Technology Data Exchange (ETDEWEB)

    D.A. Sanders et al.

    2002-01-02

    The authors report tests of redundant arrays of IDE disk drives for use in offline high energy physics data analysis. Parts costs of total systems using commodity EIDE disks are now at the $4000 per Terabyte level. Disk storage prices have now decreased to the point where they equal the cost per Terabyte of Storage Technology tape silos. The disks, however, offer far better granularity; even small institutions can afford to deploy systems. The tests include reports on software RAID-5 systems running under Linux 2.4 using Promise Ultra 100{trademark} disk controllers. RAID-5 protects data in case of a single disk failure by providing parity bits. Tape backup is not required. Journaling file systems are used to allow rapid recovery from crashes. The data analysis strategy is to encapsulate data and CPU processing power. Analysis for a particular part of a data set takes place on the PC where the data resides. The network is only used to put results together. They explore three methods of moving data between sites; internet transfers, not pluggable IDE disks in FireWire cases, and DVD-R disks.

  7. Redundant arrays of IDE drives

    International Nuclear Information System (INIS)

    Sanders, D.A.

    2002-01-01

    The authors report tests of redundant arrays of IDE disk drives for use in offline high energy physics data analysis. Parts costs of total systems using commodity EIDE disks are now at the $4000 per Terabyte level. Disk storage prices have now decreased to the point where they equal the cost per Terabyte of Storage Technology tape silos. The disks, however, offer far better granularity; even small institutions can afford to deploy systems. The tests include reports on software RAID-5 systems running under Linux 2.4 using Promise Ultra 100trademark disk controllers. RAID-5 protects data in case of a single disk failure by providing parity bits. Tape backup is not required. Journaling file systems are used to allow rapid recovery from crashes. The data analysis strategy is to encapsulate data and CPU processing power. Analysis for a particular part of a data set takes place on the PC where the data resides. The network is only used to put results together. They explore three methods of moving data between sites; internet transfers, not pluggable IDE disks in FireWire cases, and DVD-R disks

  8. 40 CFR Appendix Xiii to Part 266 - Mercury Bearing Wastes That May Be Processed in Exempt Mercury Recovery Units

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Mercury Bearing Wastes That May Be Processed in Exempt Mercury Recovery Units XIII Appendix XIII to Part 266 Protection of Environment... XIII to Part 266—Mercury Bearing Wastes That May Be Processed in Exempt Mercury Recovery Units These...

  9. Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: Providing an IND/IDE Consult Service in a Decentralized Network of Academic Healthcare Centers

    Science.gov (United States)

    Winkler, Sabune J.; Bierer, Barbara E.; Wolf, Delia

    2014-01-01

    Abstract The Food and Drug Administration (FDA) regulations require sponsors of clinical investigations involving an investigational drug or device to submit an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application. Strict adherence to applicable regulations is vital to the success of clinical research. Unlike most major pharmaceutical sponsors, investigator sponsors often do not fully appreciate their regulatory obligations nor have resources to ensure compliance. As a result they can place themselves and their institutions at risk. Nevertheless, investigator‐initiated clinical trials are vital to the further development of innovative drugs, biologics, and medical devices. The IND/IDE Subcommittee under the Regulatory Knowledge and Support Program at Harvard Catalyst, The Harvard Clinical and Translational Science Center worked in collaboration with Harvard and Harvard affiliated institutions to create and launch an IND/IDE Consult Service in a decentralized network of collaborating Academic Healthcare Centers (AHC). The IND/IDE Consult Service offers expertise, resources, and shared experiences to assist sponsor‐investigators and IRBs in meeting regulatory requirements for conducting and reviewing investigator‐initiated IND/IDE studies. The scope of the services provided by the Harvard Catalyst IND/IDE Consult Service are described, including the specifics of the service, lessons learned, and challenges faced, in a scalable model that builds inter‐institutional capacity. PMID:24455986

  10. Harvard Catalyst | The Clinical Translational Science Center IND/IDE Consult Service: providing an IND/IDE consult service in a decentralized network of academic healthcare centers.

    Science.gov (United States)

    Kim, Min J; Winkler, Sabune J; Bierer, Barbara E; Wolf, Delia

    2014-04-01

    The Food and Drug Administration (FDA) regulations require sponsors of clinical investigations involving an investigational drug or device to submit an Investigational New Drug (IND) or Investigational Device Exemption (IDE) application. Strict adherence to applicable regulations is vital to the success of clinical research. Unlike most major pharmaceutical sponsors, investigator sponsors often do not fully appreciate their regulatory obligations nor have resources to ensure compliance. As a result they can place themselves and their institutions at risk. Nevertheless, investigator-initiated clinical trials are vital to the further development of innovative drugs, biologics, and medical devices. The IND/IDE Subcommittee under the Regulatory Knowledge and Support Program at Harvard Catalyst, The Harvard Clinical and Translational Science Center worked in collaboration with Harvard and Harvard affiliated institutions to create and launch an IND/IDE Consult Service in a decentralized network of collaborating Academic Healthcare Centers (AHC). The IND/IDE Consult Service offers expertise, resources, and shared experiences to assist sponsor-investigators and IRBs in meeting regulatory requirements for conducting and reviewing investigator-initiated IND/IDE studies. The scope of the services provided by the Harvard Catalyst IND/IDE Consult Service are described, including the specifics of the service, lessons learned, and challenges faced, in a scalable model that builds inter-institutional capacity. © 2014 Wiley Periodicals, Inc.

  11. Regulatory issues associated with exclusion, exemption, and clearance related to the mining and minerals processing industries

    International Nuclear Information System (INIS)

    Metcalf, P.; Woude, S. van der; Keenan, N.; Guy, S.

    1997-01-01

    The concepts of exclusion, exemption and clearance have been established in international recommendations and, standards for radiation protection and the management of radioactive waste in recent years. The consistent application of these concepts has given rise to various problems in different spheres of use. This is particularly the case in the mining and minerals processing industries dealing with materials exhibiting elevated concentrations of naturally occurring radionuclides. This paper takes the South African mining industry as an example and highlights some of the issues that have arisen in applying these concepts within a regulatory control regime. (author)

  12. Resíduos do beneficiamento do camarão cultivado: obtenção de pigmentos carotenóides Waste from the processing of farmed shrimp: a source of carotenoid pigments

    Directory of Open Access Journals (Sweden)

    Masayoshi Ogawa

    2007-06-01

    Full Text Available A extração de pigmentos carotenóides constitui uma possível alternativa, de grande agregação de valor, para o aproveitamento da cabeça do camarão Litopenaeus vannamei. O objetivo do presente trabalho foi a identificação, a extração e a quantificação dos principais pigmentos desta matéria-prima, coletados a partir de uma planta de beneficiamento de camarão no Ceará - Brasil. Após cocção dos resíduos a 100 °C, na proporção 1:2 cabeça de camarão e água durante 15 minutos, obteve-se uma pasta de pigmentos brutos extraindo-se os carotenóides com acetona resfriada e, posteriormente, com hexano, obtendo a fase pigmento-hexano. Obteve-se também a fase DMSO, após o material ser particionado com dimetilsulfóxido, e uma fração acidificada. Estas frações sofreram evaporação e secagem, sendo os carotenóides identificados em coluna aberta, utilizando-se o parâmetro de eluição das frações, o espectro de absorção visível e o valor de Rf na camada delgada de sílica gel. Os espectros de absorção de cada fração foram obtidos a 350 a 550 nm e quantificados por cromatografia de camada delgada. Para o cálculo de carotenóides totais (37,62 µg.g-1 da pasta de pigmentos, utilizou-se o somatório das frações hexano, DMSO e acidificada, e coeficientes de extinção 2592, 2100 e 1690 referentes ao beta-caroteno, astaxantina e astaceno, respectivamente. A astaxantina foi o pigmento mais abundante (45,5%, seguido do beta-caroteno-5,6-epóxido (33,5% e do astaceno (21,0%.The extraction of carotenoid pigments from shrimp heads left over from the processing of Litopenaeus vannamei has been shown to constitute an economically feasible alternative for aggregating value to shrimp processing waste. The objective of the present study was to extract, identify and quantify the main pigments found in shrimp heads collected at a shrimp processing plant in Ceará (Brazil. Samples were cooked for 15 minutes at 100 °C in water at a

  13. Supporting Developers’ Coordination in The IDE

    NARCIS (Netherlands)

    Guzzi, A.; Bachelli, A.; Riche, Y.; Van Deursen, A.

    Teamwork in software engineering is time-consuming and problematic. In this paper, we explore how to better support developers’ collaboration in teamwork, focusing on the software implementation phase happening in the integrated development environment (IDE). Conducting a qualitative investigation,

  14. IDE Support of String-Embedded Languages

    Directory of Open Access Journals (Sweden)

    S. Grigorev

    2014-01-01

    Full Text Available Complex information systems are often implemented by using more than one programming language. Sometimes this variety takes a form of one host and one or few string-embedded languages. Textual representation of clauses in a string-embedded language is built at run time by a host program and then analyzed, compiled or interpreted by a dedicated runtime component (database, web browser etc. Most general-purpose programming languages may play the role of the host; one of the most evident examples of the string-embedded language is the dynamic SQL which was specified in ISO SQL standard and is supported by the majority of DBMS. Standard IDE functionality such as code completion or syntax highlighting can really helps the developers who use this technique. There are several tools providing this functionality, but they all process only one concrete string-embedded language and cannot be easily extended for supporting another language. We present a platform which allows to easily create tools for string-embedded language processing.

  15. Enzymatic Inactivation of Endogenous IgG by IdeS Enhances Therapeutic Antibody Efficacy.

    Science.gov (United States)

    Järnum, Sofia; Runström, Anna; Bockermann, Robert; Winstedt, Lena; Crispin, Max; Kjellman, Christian

    2017-09-01

    Endogenous plasma IgG sets an immunologic threshold that dictates the activity of tumor-directed therapeutic antibodies. Saturation of cellular antibody receptors by endogenous antibody limits antibody-dependent cell-mediated cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). Here, we show how enzymatic cleavage of IgG using the bacterial enzyme IdeS can be utilized to empty both high and low affinity Fcγ-receptors and clear the entire endogenous antibody pool. Using in vitro models, tumor animal models as well as ex vivo analysis of sera collected during a previous clinical trial with IdeS, we show how clearing of competing plasma antibody levels with IdeS unblocks cellular antibody receptors. We show that therapeutic antibodies against breast cancer (trastuzumab), colon cancer (cetuximab), and lymphomas (rituximab and alemtuzumab) can be potentiated when endogenous IgG is removed. Overall, IdeS is shown to be a potent tool to reboot the human antibody repertoire and to generate a window to preferentially load therapeutic antibodies onto effector cells and thereby create an armada of dedicated tumor-seeking immune cells. Mol Cancer Ther; 16(9); 1887-97. ©2017 AACR . ©2017 American Association for Cancer Research.

  16. Supporting mobile applications developer through Java IDE using contextual inquiry

    CSIR Research Space (South Africa)

    Samuel, OO

    2009-03-01

    Full Text Available (IDEs) for developing mobile applications. Described is the approach of this method to support mobile application developers, through the use of an IDE (NetBeans IDE in the context of this research). CI provides useful data on the typical problems found...

  17. Mini table de radionucléides

    CERN Document Server

    2015-01-01

    Cette table est un outil pratique et quotidien pour tous les travailleurs opérant au contact de radionucléides. Elle concerne tous les secteurs scientifiques et techniques, comme la médecine, la recherche ou l'industrie. La Mini Table de radionucléides a été conçue comme un instrument permettant de repérer et valider rapidement les principales caractéristiques des radionucléides les plus utilisés (environ 300) que l'on rencontre en milieu médical, industriel, nucléaire, gestion des déchets, etc. Présentée en format de poche, elle permet pour chaque radionucléide d'indiquer ses caractéristiques fondamentales : La période radioactive ; Le ou les principaux modes de désintégration ; Les principales émissions en termes d'énergie et d'intensité. Pour des caractéristiques complètes, l'ouvrage renvoie aux Tables de Données de référence. Au sein du CEA, le Laboratoire National Henri Becquerel (LNHB) est mandaté par le Laboratoire National de Métrologie et d'Essais (LNE) comme laboratoir...

  18. Coqoon - An IDE for Interactive Proof Development in Coq

    DEFF Research Database (Denmark)

    Faithfull, Alexander; Bengtson, Jesper; Tassi, Enrico

    2016-01-01

    User interfaces for interactive proof assistants have always lagged behind those for mainstream programming languages. Whereas integrated development environments—IDEs—have support for features like project management, version control, dependency analysis and incremental project compilation, “IDE...... these projects using the Eclipse common build system. Coqoon takes advantage of the latest features of Coq, including asynchronous and parallel processing of proofs, and—when used together with a third-party OCaml extension for Eclipse—can even be used to work on large developments containing Coq plugins....

  19. 40 CFR Appendix Xii to Part 266 - Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Nickel or Chromium-Bearing Materials that may be Processed in Exempt Nickel-Chromium Recovery Furnaces XII Appendix XII to Part 266... FACILITIES Pt. 266, App. XII Appendix XII to Part 266—Nickel or Chromium-Bearing Materials that may be...

  20. Terabyte IDE RAID-5 Disk Arrays

    Energy Technology Data Exchange (ETDEWEB)

    David A. Sanders et al.

    2003-09-30

    High energy physics experiments are currently recording large amounts of data and in a few years will be recording prodigious quantities of data. New methods must be developed to handle this data and make analysis at universities possible. We examine some techniques that exploit recent developments in commodity hardware. We report on tests of redundant arrays of integrated drive electronics (IDE) disk drives for use in offline high energy physics data analysis. IDE redundant array of inexpensive disks (RAID) prices now are less than the cost per terabyte of million-dollar tape robots! The arrays can be scaled to sizes affordable to institutions without robots and used when fast random access at low cost is important.

  1. Building an IDE for the Calculational Derivation of Imperative Programs

    Directory of Open Access Journals (Sweden)

    Dipak L. Chaudhari

    2015-08-01

    Full Text Available In this paper, we describe an IDE called CAPS (Calculational Assistant for Programming from Specifications for the interactive, calculational derivation of imperative programs. In building CAPS, our aim has been to make the IDE accessible to non-experts while retaining the overall flavor of the pen-and-paper calculational style. We discuss the overall architecture of the CAPS system, the main features of the IDE, the GUI design, and the trade-offs involved.

  2. Pneumonia lipóide

    Directory of Open Access Journals (Sweden)

    Gunther Kissmann

    2008-07-01

    Full Text Available Resumo: Dentre as afecções pulmonares exógenas, a pneumonia lipóide (PL, causada pela broncoaspiração de lipídeos, é uma doença pouco diagnosticada. Ela resulta da reacção tipo corpo estranho que se segue à presença de material lipídico dentro do parênquima pulmonar. Em geral, o agente etiológico é o óleo mineral utilizado como agente laxativo. Doentes com histórico de constipação intestinal e uso crónico de óleo mineral, com tosse e dispneia, devem ser pesquisados quanto a esta doença. Apresentamos um caso de pneumonia lipóide associada ao uso de óleo mineral como agente laxativo, acentuamos as dificuldades relacionadas com a definição diagnóstica e revemos a literatura pertinente ao tema.Rev Port Pneumol 2008; XIV (4: 545-549 Abstract: Lipoid pneumonia (LP is a pneumonitis resulting from the aspiration of lipids, and is commonly associated with the use of mineral oil as a laxative. LP is relatively unfamiliar to clinicians and is probably underdiagnosed. Making a diagnosis of LP requires a high degree of clinical suspicion. The aim of this publication are to present a case of a patient with LP and to increase physician awareness of LP, its diagnosis and prevention.Rev Port Pneumol 2008; XIV (4: 545-549 Palavras-chave: Pneumonia lipóide, óleo mineral, doenças pulmonares intersticiais, idoso, Key-words: Lipid pneumonia, mineral oil, interstitial lung diseases, aged

  3. Tumores dermóides e epidermóides intra-espinhas

    Directory of Open Access Journals (Sweden)

    Oscar Fontenelle Filho

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3; os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1 e lombar (caso 2, respectivamente, sendo o primeiro intramedular e o segundo intradural. Em dois casos (casos 2 e 3 os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3 foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2.

  4. Sexing the human skull through the mastoid process Determinação do sexo em crânios humanos através do processo mastóide

    Directory of Open Access Journals (Sweden)

    Luiz Airton Saavedra de Paiva

    2003-01-01

    Full Text Available OBJECTIVE: The purpose of this study was to evaluate the significance for sex determination of the measurement of the area formed by the xerographic projection of 3 craniometric points related to the mastoid process: the porion, asterion, and mastoidale points. METHOD: Sixty skulls, 30 male and 30 female, were analyzed. A xerographic copy of each side of the skull was obtained. On each xerographic copy, the craniometric points were marked to demarcate a triangle. The area (mm² of the demarcated triangle for each side of the skull (right (D and left (E sides was determined, and the total value of these measures (T was calculated. RESULTS: Concerning the right area of the male and female skulls, 60% of the values overlapped; for the left area, 51.67% overlapped, and for the total area, 36.67% overlapped. The analysis of the differences between the sexes in the areas studied was significant for the 3 areas. Regarding the total area, which is the preferred measurement because of the asymmetry between the sides of the skull, the value of the mean was 1505.32 mm² for male skulls, which was greater than the maximum value obtained in the female skulls. The value of the mean for female skulls was 1221.24 mm², less than the minimum value obtained for the male skulls. CONCLUSIONS: This study demonstrates a significant result in the 3 studied areas, (D, (E, and (T. The total area values show less overlapping of values between the sexes, and therefore can be used for sexing human skulls. For the population studied, values of the total area that were greater than or equal to 1447.40 mm² belonged to male crania (95% confidence. Values for this area that were less than or equal to 1260.36 mm² belonged to female crania (95% confidence.OBJETIVO: Avaliar a significância da medida da área formada pela projeção xerográfica de três pontos craniométricos relacionados ao processo mastóide, que são, o porion, o asterion e o mastoidale, na determinação do

  5. Cisto dermóide cerebelar

    Directory of Open Access Journals (Sweden)

    Walter Pereira

    1964-06-01

    Full Text Available Os autores relatam um caso de cisto dermóide cerebelar, único encontrado entre 513 tumores intracranianos operados de janeiro de 1945 a março de 1963, confirmando sua raridade. Tratava-se de criança que apresentava síndrome de hipertensão intracraniana e quadro cerebelar instalados dois meses antes da internação. Os exames complementares levaram ao diagnóstico provável de meduloblastoma cerebelar. Foi feita a abertura da lâmina terminal para aliviar a hipertensão intracraniana e, ulteriormente, cobaltoterapia visando a fossa poterior. Com estas medidas houve apenas discreta melhora do quadro de hipertensão intracraniana, não se alterando o quadro cerebelar. Cogitava-se da intervenção direta na fossa craniana posterior quando ocorreu osteomielite do retalho da craniotomia frontal. O osso contaminado foi retirado, seguindo-se a esta intervenção hipertermia acentuada e convulsões generalizadas, vindo a paciente a falecer. A necropsia mostrou, além de meningite purulenta, a existência de cisto dermóide cerebelar direito, contendo grande quantidade de substância sebácea e alguns pêlos. O exame histopatológico confirmou o diagnóstico microscópico, mostrando tratar-se de tecidos derivados do ectoderma e do mesoderma.

  6. Frutos de melão submetidos a pré-tratamentos com hidrocolóides: efeitos do processo de congelamento sobre a microestrutura celular Pretreatment of melons with hydrocolloids: effect of the freezing process on the cell microstructures

    Directory of Open Access Journals (Sweden)

    Jaime V. Resende

    2002-12-01

    Full Text Available Neste trabalho, o uso de hidrocolóides constituídos de pectina (1%, carboximetilcelulose (CMC 0.5% e amido gelatinizado (5% adicionados ou não de sacarose (15% e nitrato de cálcio (0.5% foi testado com o objetivo de se avaliar a influência destes sistemas sobre os parâmetros de qualidade de melões congelados com diferentes velocidades de resfriamento. Foram avaliados parâmetros tais como sólidos solúveis totais, perda de fluido celular por exsudação e capacidade de retenção de água após o descongelamento. As rupturas do tecido causadas pelo crescimento de cristais de gelo foram visualizadas por fotomicrografias obtidas por microscopia ótica e as disposições dos sistemas de hidrocolóides junto a parede celular puderam ser analisadas por microscopia eletrônica de varredura (SEM do material congelado e liofilizado. Os parâmetros avaliados e as análises microscópicas da estrutura celular permitiram estabelecer alguns efeitos interativos entre os sistemas de hidrocolóides e a parede celular, responsáveis pela obtenção de estruturas menos danificadas. Estudos histológicos por microscopia ótica permitiram verificar os efeitos das interações sobre a resistência da parede ao rompimento celular. Os tratamentos com sistemas constituídos de amido gelatinizado e pectina, adicionados de sacarose e íons cálcio foram os que apresentaram os melhores resultados na manutenção da estrutura, menor perda de fluido e melhor textura do material descongelado. Os tratamentos com cálcio foram os principais responsáveis pela manutenção da firmeza dos frutos.In this research, the use of hydrocolloid constituted of pectin (1%, carboxymethylcellulose (CMC (0.5% and gelatinized starch (5%, added to sucrose (15%, was tested to evaluate the influence of these compounds on the quality parameters of frozen melons under various cooling rates. The evaluation parameters were soluble solids, loss of cellular fluid by exsudation and water

  7. Evaluation of total carotenoids, alpha- and beta-carotene in carrots (Daucus carota L. during home processing Avaliação de carotenóides totais, alfa e beta-caroteno em cenoura (Daucus carota L. durante processamento a nível doméstico

    Directory of Open Access Journals (Sweden)

    Helena Maria PINHEIRO-SANT’ANA

    1998-04-01

    Full Text Available This study aims to analyze the influence of dehydration and different preparation methods during home processing related toalpha-carotene, beta-carotene and total carotenoids stability in carrots. Vitamin A values were evaluated after different treatments. Thus, carrots were submitted to steam cooking, water cooking with and without pressure, moist/dry cooking and conventional dehydration. Determination of alpha- and beta-carotenes was made by High-Performance Liquid Chromatography (HPLC (conditions were developed by us using spectrophotometric detection visible-UV at 470 nm; a RP-18 column and methanol: acetonitrile: ethyl acetate (80: 10: 10 as mobile phase. Total carotenoids quantification was made by 449 nm spectrophotometer. The retention of the analyzed carotenoids ranged from 60.13 to 85.64%. Water cooking without pressure promoted higher retention levels of alpha- and beta-carotene and vitamin A values, while water cooking with pressure promoted higher retention levels of total carotenoids. Dehydration promoted the highest carotenoid losses. The results showed that, among the routinely utilized methods under domestic condition, cooking without pressure, if performed under controlled time and temperature, is the best method as it reduces losses in the amount of alpha- and beta-carotene, the main carotenoids present in the carrots. Despite the significant carotenoid losses, carrots prepared through domestic methods, remain a rich source of provitamin A.O presente estudo teve como objetivo analisar a influência da desidratação e de diferentes métodos de preparo a nível doméstico sobre a estabilidade de alfa-caroteno, beta-caroteno e carotenóides totais em cenouras. Os valores de vitamina A foram avaliados após os diferentes tratamentos. Para tanto, amostras de cenoura foram submetidas à cocção a vapor, cocção em água com e sem pressão, cocção úmida/seca e à desidratação convencional. Para a determinação de alfa e beta

  8. Integrated titanium dioxide (TiO_2) nanoparticles on interdigitated device electrodes (IDEs) for pH analysis

    International Nuclear Information System (INIS)

    Azizah, N.; Gopinath, Subash C. B.; Nadzirah, Sh.; Farehanim, M. A.; Fatin, M. F.; Ruslinda, A. R.; Hashim, U.; Arshad, M. K. Md.; Ayub, R. M.

    2016-01-01

    Titanium dioxide (TiO_2) nanoparticles based Interdigitated Device Electrodes (IDEs) Nanobiosensor device was developed for intracellular biochemical detection. Fabrication and characterization of pH sensors using IDE nanocoated with TiO_2 was studied in this paper. In this paper, a preliminary assessment of this intracellular sensor with electrical measurement under different pH levels. 3-aminopropyltriethoxysilane (APTES) was used to enhance the sensitivity of titanium dioxide layer as well as able to provide surface modification by undergoing protonation and deprotonation process. Different types of pH solution provide different resistivity and conductivity towards the surface. Base solution has the higher current compared to an acid solution. Amine and oxide functionalized TiO_2 based IDE exhibit pH-dependent could be understood in terms of the change in surface charge during protonation and deprotonation. The simple fabrication process, high sensitivity, and fast response of the TiO_2 based IDEs facilitate their applications in a wide range of areas. The small size of semiconductor TiO_2 based IDE for sensitive, label-free, real time detection of a wide range of biological species could be explored in vivo diagnostics and array-based screening.

  9. Test Marketing Exemption (TME) for New Chemical Review under TSCA

    Science.gov (United States)

    Under section 5 of TSCA, EPA established an exemption for certain chemicals that are manufactured (including imported) for test marketing. You can learn more here about the requirements of this exemption, along with the review and submission process.

  10. Tüdruku muutunud veregrupp andis teadlastele idee / Alo Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Alo

    2008-01-01

    Austraalia tüdruk on esimene teadaolev inimene, kelle organism on muutnud veregruppi ning võtnud üle siirdatud organi immuunsüsteemi. Teadlastele andis see idee äratõukereaktsioonide vältimiseks organisiirdamistel

  11. Experimental characterization of PZT fibers using IDE electrodes

    Science.gov (United States)

    Wyckoff, Nicholas; Ben Atitallah, Hassene; Ounaies, Zoubeida

    2016-04-01

    Lead zirconate titanate (PZT) fibers are mainly used in active fiber composites (AFC) where they are embedded in a polymer matrix. Interdigitated electrodes (IDE) along the direction of the fibers are used to achieve planar actuation, hereby exploiting the d33 coefficient of PZT. When embedded in the AFC, the PZT fibers are subjected to mechanical loading as well as non-uniform electric field as a result of the IDEs. Therefore, it is important to characterize the electrical and electromechanical behavior of these fibers ex-situ using the IDE electrodes to assess the impact of nonuniform electric field on the properties of the fibers. For that reason, this work aims at quantifying the impact of IDE electrodes on the electrical and electromechanical behavior of PZT fibers, which is necessary for their successful implementation in devices like AFC. The tested fibers were purchased from Advanced Cerametrics and they have an average diameter of 250 micrometers. The IDE electrodes were screen printed on an acrylic substrate. The PZT fibers were subjected to frequency sweeps at low voltages to determine permittivity for parallel and interdigitated electrodes. The piezoelectric e33 constant is determined from electromechanical testing of PZT fibers in parallel electrodes to compare the electromechanical behavior for PZT in bulk and fiber form. The dielectric constant and e33 were found to be lower for the IDE and parallel electrodes compared to bulk but comparable to results published in literature.

  12. High-throughput oxidation screen of antibody-drug conjugates by analytical protein A chromatography following IdeS digest.

    Science.gov (United States)

    Buecheler, Jakob W; Winzer, Matthias; Weber, Christian; Gieseler, Henning

    2018-05-01

    Oxidation of protein therapeutics is a major chemical degradation pathway which may impact bioactivity, serum half-life and stability. Therefore, oxidation is a relevant parameter which has to be monitored throughout formulation development. Methods such as HIC, RPLC and LC/MS achieve a separation of oxidized and non-oxidized species by differences in hydrophobicity. Antibody-drug conjugates (ADC) although are highly more complex due to the heterogeneity in linker, drug, drug-to-antibody ratio (DAR) and conjugation site. The analytical protein A chromatography can provide a simple and fast alternative to these common methods. A miniature analytical protein A chromatography method in combination with an IdeS digest was developed to analyse ADCs. The IdeS digest efficiency of an IgG1 was monitored using SEC-HPLC and non-reducing SDS-PAGE. An antibody-fluorescent dye conjugate was conjugated at different dye-to-antibody ratios as model construct to mimic an ADC. With IdeS, an almost complete digest of a model IgG1 can be achieved (digested protein amount >98%). This enables subsequent analytical protein A chromatography, which consequently eliminates any interference of payload with the stationary phase. A novel high-throughput method for an interchain cysteine-linked ADC oxidation screens during formulation development was developed. © 2018 Royal Pharmaceutical Society.

  13. Carcinoma mucoepidermóide Mucoepidermoid carcinoma

    Directory of Open Access Journals (Sweden)

    CRISTIANO FEIJÓ ANDRADE

    2002-11-01

    Full Text Available O carcinoma mucoepidermóide é uma neoplasia infreqüente da árvore traqueobrônquica e de etiologia ainda indeterminada. Sua localização endobrônquica preferencial freqüentemente causa sintomas respiratórios obstrutivos e pneumopatias de resolução lenta. Normalmente, são tumores de crescimento lento, mas que podem apresentar comportamento agressivo, com invasão local e metástases para linfonodos, dependendo das suas características histopatológicas. O tratamento de eleição é o cirúrgico, com ressecção completa, seja através de lobectomia ou broncotomia e broncoplastia. O prognóstico dependerá do grau de diferenciação celular desses tumores. Relata-se um caso dessa rara neoplasia descrevendo suas características clínicas, radiológicas e o tratamento cirúrgico.Mucoepidermoid carcinoma is an uncommon neoplasm of the tracheobronchial tree, of unknown etiology. Its preferred endobronchial location often results in respiratory symptoms such as obstruction of the airways and lung diseases of slow recovery. They usually are slow growing tumors although they may present an aggressive behavior with local invasion and lymph node metastases depending on their histopathologic characteristics. The mainstay therapy is complete surgical resection either by means of lobectomy or by lung sparing procedures such as bronchotomy and bronchoplasty. Prognosis depends upon the degree of cellular differentiation of the tumors. The authors report a case of this rare neoplasia and describe the clinical and radiographic characteristics, and the surgical treatment.

  14. Thymoquinone-rich fraction nanoemulsion (TQRFNE) decreases Aβ40 and Aβ42 levels by modulating APP processing, up-regulating IDE and LRP1, and down-regulating BACE1 and RAGE in response to high fat/cholesterol diet-induced rats.

    Science.gov (United States)

    Ismail, Norsharina; Ismail, Maznah; Azmi, Nur Hanisah; Bakar, Muhammad Firdaus Abu; Yida, Zhang; Abdullah, Maizaton Atmadini; Basri, Hamidon

    2017-11-01

    Though the causes of Alzheimer's disease (AD) are yet to be understood, much evidence has suggested that excessive amyloid-β (Aβ) accumulation due to abnormal amyloid-β precursor protein (APP) processing and Aβ metabolism are crucial processes towards AD pathogenesis. Hence, approaches aiming at APP processing and Aβ metabolism are currently being actively pursued for the management of AD. Studies suggest that high cholesterol and a high fat diet have harmful effects on cognitive function and may instigate the commencement of AD pathogenesis. Despite the neuropharmacological attributes of black cumin seed (Nigella sativa) extracts and its main active compound, thymoquinone (TQ), limited records are available in relation to AD research. Nanoemulsion (NE) is exploited as drug delivery systems due to their capacity of solubilising non-polar active compounds and is widely examined for brain targeting. Herewith, the effects of thymoquinone-rich fraction nanoemulsion (TQRFNE), thymoquinone nanoemulsion (TQNE) and their counterparts' conventional emulsion in response to high fat/cholesterol diet (HFCD)-induced rats were investigated. Particularly, the Aβ generation; APP processing, β-secretase 1 (BACE1), γ-secretases of presenilin 1 (PSEN1) and presenilin 2 (PSEN2), Aβ degradation; insulin degrading enzyme (IDE), Aβ transportation; low density lipoprotein receptor-related protein 1 (LRP1) and receptor for advanced glycation end products (RAGE) were measured in brain tissues. TQRFNE reduced the brain Aβ fragment length 1-40 and 1-42 (Aβ40 and Aβ42) levels, which would attenuate the AD pathogenesis. This reduction could be due to the modulation of β- and γ-secretase enzyme activity, and the Aβ degradation and transportation in/out of the brain. The findings show the mechanistic actions of TQRFNE in response to high fat and high cholesterol diet associated to Aβ generation, degradation and transportation in the rat's brain tissue. Copyright © 2017 Elsevier

  15. Concordant association of insulin degrading enzyme gene (IDE variants with IDE mRNA, Abeta, and Alzheimer's disease.

    Directory of Open Access Journals (Sweden)

    Minerva M Carrasquillo

    2010-01-01

    Full Text Available The insulin-degrading enzyme gene (IDE is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD.We examined conserved regions of IDE and its 10 kb flanks in 269 AD cases and 252 controls thereby identifying 17 putative functional polymorphisms. These variants formed eleven haplotypes that were tagged with ten variants. Four of these showed significant association with IDE transcript levels in samples from 194 LOAD cerebella. The strongest, rs6583817, which has not previously been reported, showed unequivocal association (p = 1.5x10(-8, fold-increase = 2.12,; the eleven haplotypes were also significantly associated with transcript levels (global p = 0.003. Using an in vitro dual luciferase reporter assay, we found that rs6583817 increases reporter gene expression in Be(2-C (p = 0.006 and HepG2 (p = 0.02 cell lines. Furthermore, using data from a recent genome-wide association study of two Croatian isolated populations (n = 1,879, we identified a proxy for rs6583817 that associated significantly with decreased plasma Abeta40 levels (ss = -0.124, p = 0.011 and total measured plasma Abeta levels (b = -0.130, p = 0.009. Finally, rs6583817 was associated with decreased risk of LOAD in 3,891 AD cases and 3,605 controls. (OR = 0.87, p = 0.03, and the eleven IDE haplotypes (global p = 0.02 also showed significant association.Thus, a previously unreported variant unequivocally associated with increased IDE expression was also associated with reduced plasma Abeta40 and decreased LOAD susceptibility. Genetic association between LOAD and IDE has been difficult to replicate. Our findings suggest that targeted testing of expression SNPs (eSNPs strongly associated with altered transcript levels in autopsy brain samples may be a powerful way to identify genetic associations with LOAD that would otherwise be difficult to detect.

  16. 29 CFR 779.347 - Exemption limited to “recognized retail establishment”; factories not exempt.

    Science.gov (United States)

    2010-07-01

    ... under the exemption are custom tailor shops, candy shops, ice cream parlors, bakeries, drug stores, optometrist establishments, retail ice plants and other local retail establishments which make or process the... industry. This test limits the exemption to retail establishments only, and excludes factories as such and...

  17. IdeMatch – a digital tool for innovative, social and transdisciplinary learning designs

    DEFF Research Database (Denmark)

    Hansen, Gitte Riis

    This paper presents IdeMatch which is a digital tool implemented in University College Zealand (UCZ) in spring 2015. IdeMatch is based on educational policies and educational structural intentions and needs, and this paper examines and offers an outline for the learning perspective and the impact...... that IdeMatch has got concerning teaching and learning designs....

  18. U.S. Department of Energy FreedomCar & Vehicle Technologies Program CARB Executive Order Exemption Process for a Hydrogen-fueled Internal Combustion engine Vehicle -- Status Report

    Energy Technology Data Exchange (ETDEWEB)

    2008-04-01

    The CARB Executive Order Exemption Process for a Hydrogen-fueled Internal Combustion Engine Vehicle was undertaken to define the requirements to achieve a California Air Resource Board Executive Order for a hydrogenfueled vehicle retrofit kit. A 2005 to 2006 General Motors Company Sierra/Chevrolet Silverado 1500HD pickup was assumed to be the build-from vehicle for the retrofit kit. The emissions demonstration was determined not to pose a significant hurdle due to the non-hydrocarbon-based fuel and lean-burn operation. However, significant work was determined to be necessary for Onboard Diagnostics Level II compliance. Therefore, it is recommended that an Experimental Permit be obtained from the California Air Resource Board to license and operate the vehicles for the durability of the demonstration in support of preparing a fully compliant and certifiable package that can be submitted.

  19. SPEEDY: An Eclipse-based IDE for invariant inference

    Directory of Open Access Journals (Sweden)

    David R. Cok

    2014-04-01

    Full Text Available SPEEDY is an Eclipse-based IDE for exploring techniques that assist users in generating correct specifications, particularly including invariant inference algorithms and tools. It integrates with several back-end tools that propose invariants and will incorporate published algorithms for inferring object and loop invariants. Though the architecture is language-neutral, current SPEEDY targets C programs. Building and using SPEEDY has confirmed earlier experience demonstrating the importance of showing and editing specifications in the IDEs that developers customarily use, automating as much of the production and checking of specifications as possible, and showing counterexample information directly in the source code editing environment. As in previous work, automation of specification checking is provided by back-end SMT solvers. However, reducing the effort demanded of software developers using formal methods also requires a GUI design that guides users in writing, reviewing, and correcting specifications and automates specification inference.

  20. Tumor Filóides Borderline: Relato de caso

    Directory of Open Access Journals (Sweden)

    MARINA PIRASSOL TEPEDINO

    2016-12-01

    Full Text Available O presente artigo tem o objetivo de narrar o caso de uma jovem de 24 anos, que teve quadro de Tumor Filóides do tipo borderline, evidenciado durante cirurgia de excisão de fibroadenoma, e diagnosticado por exame histopatológico da lesão, sendo futuramente reabordado com nova cirurgia. O Tumor Filóides é uma neoplasia fibroepitelial incomum da mama, representando de 0,3 a 0,9% de todos os tumores primários daquele órgão. É comumente vista entre pacientes com 40-50 anos. Sendo mais raro ainda sua apresentação em jovens. Por fim este artigo apresenta breve revisão de literatura, mostrando que a conduta utilizada no caso foi correta.

  1. Coqoon - An IDE for Interactive Proof Development in Coq

    OpenAIRE

    Faithfull, Alexander; Bengtson, Jesper; Tassi, Enrico

    2016-01-01

    User interfaces for interactive proof assistants have always lagged behind those for mainstream programming languages. Whereas integrated development environments—IDEs—have support for features like project management, version control, dependency analysis and incremental project compilation, “IDE”s for proof assistants typically only operate on files in isolation, relying on external tools to integrate those files into larger projects. In this paper we present Coqoon, an IDE for Coq developme...

  2. A monomeric variant of insulin degrading enzyme (IDE loses its regulatory properties.

    Directory of Open Access Journals (Sweden)

    Eun Suk Song

    2010-03-01

    Full Text Available Insulin degrading enzyme (IDE is a key enzyme in the metabolism of both insulin and amyloid beta peptides. IDE is unique in that it is subject to allosteric activation which is hypothesized to occur through an oligomeric structure.IDE is known to exist as an equilibrium mixture of monomers, dimers, and higher oligomers, with the dimer being the predominant form. Based on the crystal structure of IDE we deleted the putative dimer interface in the C-terminal region, which resulted in a monomeric variant. Monomeric IDE retained enzymatic activity, however instead of the allosteric behavior seen with wild type enzyme it displayed Michaelis-Menten kinetic behavior. With the substrate Abz-GGFLRKHGQ-EDDnp, monomeric IDE retained approximately 25% of the wild type activity. In contrast with the larger peptide substrates beta-endorphin and amyloid beta peptide 1-40, monomeric IDE retained only 1 to 0.25% of wild type activity. Unlike wild type IDE neither bradykinin nor dynorphin B-9 activated the monomeric variant of the enzyme. Similarly, monomeric IDE was not activated by polyphosphates under conditions in which the activity of wild type enzyme was increased more than 50 fold.These findings serve to establish the dimer interface in IDE and demonstrate the requirement for an oligomeric form of the enzyme for its regulatory properties. The data support a mechanism where the binding of activators to oligomeric IDE induces a conformational change that cannot occur in the monomeric variant. Since a conformational change from a closed to a more open structure is likely the rate-determining step in the IDE reaction, the subunit induced conformational change likely shifts the structure of the oligomeric enzyme to a more open conformation.

  3. Cupric natural zeolites as microbic ides

    International Nuclear Information System (INIS)

    Contreras A, D.; Olguin G, M. T.; Alcantara D, D.; Burrola A, C.

    2009-01-01

    The Escherichia coli and the Candida albicans are considered contamination indicators for what these organisms reflect the water quality. The natural zeolites by their characteristics and properties, they could incorporate to a waters treatment system, as ion exchange, adsorbents and/or microbiocid agents, representing an alternative method of low cost. Inside this investigation work was found that depending on the microorganism type, it varies the quantity of cupric zeolite that is required to carry out the water disinfection, being great for the case of yeasts than the bacteria s. In addition to that marked differences are presented in the required time to reach this process. The characterization of the natural zeolite material, sodium and cupric, was realized by means of scanning electron microscopy, determining the elementary composition (Energy Dispersive Spectroscopy) of each one of them, and by X-ray diffraction. (Author)

  4. Requesting and granting exemptions to nuclear safety rules

    International Nuclear Information System (INIS)

    1995-02-01

    This standard provides an acceptable process for requesting and granting exemptions to DOE Nuclear Safety rules. The provisions of 10 CFR Part 820.63 allow DOE to determine the procedures to be used to comply with the responsibilities regarding exemption relief from DOE nuclear safety rules. The procedure in this standard defines an acceptable method for meeting these responsibilities

  5. Hexaaquamagnesium dibromide 5-(pyridinium-3-yltetrazol-1-ide

    Directory of Open Access Journals (Sweden)

    Xin-Yuan Chen

    2011-01-01

    Full Text Available In the title compound, [Mg(H2O6]Br2·2C6H5N5, the MgII atom, lying on an inversion center, is coordinated by six water molecules in a distorted octahedral geometry. The pyridine and tetrazole rings in the 5-(pyridinium-3-yltetrazol-1-ide zwitterion are nearly coplanar, twisted from each other by a dihedral angle of 5.70 (1°. The zwitterions, Br anions and complex cations are connected by O—H...Br, O—H...N and N—H...Br hydrogen bonds, leading to the formation of a three-dimensional network.

  6. Evaluation of factor IX deficiency by interdigitated electrode (IDE)

    Science.gov (United States)

    Gopinath, Subash C. B.; Hashim, Uda; Uda, M. N. A.

    2017-03-01

    Factor IX deficiency is the main cause of hemophilia A and B. This a severe excessive bleeding disorder that can even kill the patient if not treated with the right prescription of Factor IX hormone to stop the bleeding. The bleeding can be caused by an injury or even a sudden bleeding in some very rare cases. To find the Factor IX effectiveness and to understand the deficiency more carefully for the future of medicine, experiments are conducted to test the Factor IX using the Interdigitated Electrode (IDE) and gold Nanoparticle with the help of Nanoelectrical technology.

  7. An ethanol-based process to simultaneously extract and fractionate carotenoids from Mauritia flexuosa L. Pulp Uso do etanol comercial para extração e fracionamento simultâneo de carotenóides de Mauritia flexuosa L. Pulp

    Directory of Open Access Journals (Sweden)

    Bernardo Dias Ribeiro

    2010-09-01

    Full Text Available Mauritia vinifera (buriti is a palm tree that grows wild in different areas of Brazil, particularly in the Amazonian region. The buriti oil is rich in carotenoids, especially in β-carotene. The growing interest in other natural sources of β-carotene has stimulated the industrial use of buriti as a raw material for pulp oil extraction. Most processes are based on the conventional technologies, involving drying and pressing the pulp for oil recovery and further separation of carotenoids in a liquid phase using organics solvents. In the present work, the ethanol-based process was evaluated for simultaneous carotenoids recovering and fractionating from buriti pulp. The raw material and ethanol, 1:4 ratio, were placed in an erlenmeyer flask and maintained at 30rpm for 1 hour in a temperature-controlled bath at 65ºC. The mixture was filtered under vacuum and cooling at 10ºC to allow for the separation of the solvent in two phases. Carotenoids composition, determined by HPLC, has indicated a β-carotene concentration about 12 times greater in the lower phase than in the upper phase. The profile of the carotenoids in the denser phase is quite similar to that of raw buriti oil, and the concentration of total carotenoids is 40% higher than that of the original raw oil, making the ethanol-based process particularly attractive for industrial applications.Mauritia vinifera (buriti é uma palmeira nativa de diferentes regiões do Brasil, particularmente na região Amazônica. O óleo de buriti é rico em carotenóides, especialmente em β-caroteno. A demanda por fontes naturais de β-caroteno tem contribuído para aumentar a industrialização do fruto de buriti pelas usinas de extração de óleos vegetais. O processo mais adotado baseia-se em tecnologias convencionais envolvendo as etapas de despolpamento, secagem e prensagem da polpa para extração do óleo, seguida da separação dos carotenoides em uma fase líquida usando solventes org

  8. Accelerating the creation of customized, language-specific IDEs in eclipse

    NARCIS (Netherlands)

    Charles, P.; Fuhrer, R.M.; Sutton, S.M.; Duesterwald, E.; Vinju, J.J.

    2009-01-01

    Full-featured integrated development environments have become critical to the adoption of new programming languages. Key to the success of these IDEs is the provision of services tailored to the languages. However, modern IDEs are large and complex, and the cost of constructing one from scratch can

  9. Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

    Science.gov (United States)

    Hilgers, Ralf-Dieter; Bogdan, Malgorzata; Burman, Carl-Fredrik; Dette, Holger; Karlsson, Mats; König, Franz; Male, Christoph; Mentré, France; Molenberghs, Geert; Senn, Stephen

    2018-05-11

    IDeAl (Integrated designs and analysis of small population clinical trials) is an EU funded project developing new statistical design and analysis methodologies for clinical trials in small population groups. Here we provide an overview of IDeAl findings and give recommendations to applied researchers. The description of the findings is broken down by the nine scientific IDeAl work packages and summarizes results from the project's more than 60 publications to date in peer reviewed journals. In addition, we applied text mining to evaluate the publications and the IDeAl work packages' output in relation to the design and analysis terms derived from in the IRDiRC task force report on small population clinical trials. The results are summarized, describing the developments from an applied viewpoint. The main result presented here are 33 practical recommendations drawn from the work, giving researchers a comprehensive guidance to the improved methodology. In particular, the findings will help design and analyse efficient clinical trials in rare diseases with limited number of patients available. We developed a network representation relating the hot topics developed by the IRDiRC task force on small population clinical trials to IDeAl's work as well as relating important methodologies by IDeAl's definition necessary to consider in design and analysis of small-population clinical trials. These network representation establish a new perspective on design and analysis of small-population clinical trials. IDeAl has provided a huge number of options to refine the statistical methodology for small-population clinical trials from various perspectives. A total of 33 recommendations developed and related to the work packages help the researcher to design small population clinical trial. The route to improvements is displayed in IDeAl-network representing important statistical methodological skills necessary to design and analysis of small-population clinical trials. The methods

  10. Tumores dermóides e epidermóides intra-espinhas Intraspinal epidermoid and dermoid tumours

    Directory of Open Access Journals (Sweden)

    Oscar Fontenelle Filho

    1971-03-01

    Full Text Available São relatados dois casos de tumores epidermóides e um de tumor dermóide, todos intrarraquianos. Este último era de localização epidural ao nível da coluna torácica (caso 3; os dois tumores epidermóides situavam-se na coluna tóraco-lombar (caso 1 e lombar (caso 2, respectivamente, sendo o primeiro intramedular e o segundo intradural. Em dois casos (casos 2 e 3 os tumores associavam-se a fístula dérmica congênita. Um paciente (caso 3 foi operado aos dois meses de idade; a descoberta do tumor deveu-se à realização da raquimanometria que revelou bloqueio, apesar do paciente não apresentar qualquer sinal neurológico de compressão medular. Os autores são de opinião que, em presença de fístula dérmica congênita ao nível da coluna vertebral, principalmente quando localizada acima do segmento lombosacro, deve-se sempre suspeitar da possibilidade do tumor epidermóide ou dermóide intrarraquiano, mesmo na ausência de sinais neurológicos. A combinação de sintomas neurológicos de longa duração, a evidência radiológica de erosão e alargamento do canal raquiano e a história de fístula dérmica congênita proporcionaram o diagnóstico pré-operatório correto no caso 2.Two cases of epidermoids and one case of dermoid intraspinal tumours are reported. The last case was located at thoracic level (T7 (case 3 and was epidural in localization. The two epidermoids tumours were located at the thoracic-lumbar (case 1 and lumbar (case 2 level, respectively; the first was intramedullary and the second subdural in localization. In two (cases 2 and 3 there was associated communicating pilonidal sinuses. One of the patients (case 3 was operated within the second month of age. The early discovery of the tumour in this patient was made through a lumbar raquimanometry that disclosed a complete subarachnoid block. In spite of this the patient did not presented any neurological symptoms. The authors are of opinion that in presence of a

  11. FoCaLiZe: Inside an F-IDE

    Directory of Open Access Journals (Sweden)

    François Pessaux

    2014-04-01

    Full Text Available For years, Integrated Development Environments have demonstrated their usefulness in order to ease the development of software. High-level security or safety systems require proofs of compliance to standards, based on analyses such as code review and, increasingly nowadays, formal proofs of conformance to specifications. This implies mixing computational and logical aspects all along the development, which naturally raises the need for a notion of Formal IDE. This paper examines the FoCaLiZe environment and explores the implementation issues raised by the decision to provide a single language to express specification properties, source code and machine-checked proofs while allowing incremental development and code reusability. Such features create strong dependencies between functions, properties and proofs, and impose an particular compilation scheme, which is described here. The compilation results are runnable OCaml code and a checkable Coq term. All these points are illustrated through a running example.

  12. Il dito di Galileo le dieci grandi idee della scienza

    CERN Document Server

    Atkins, Peter

    2004-01-01

    Domande e risposte per dieci idee che hanno plasmato il mondo di oggi. Possiamo rintracciare l'origine e il divenire del cosmo? Perché spazio e tempo formano una cosa sola? Che cosa significa l'evoluzione del vivente? Perché il DNA è così importante? Perché il mondo ha bisogno di energia? E com'è che l'aumento dell'entropia scandisce il cambiamento dell'intero universo? Cosa sono gli atomi e cosa c'è di più piccolo di essi? Perché la simmetria della natura e dell'arte cattura il nostro senso della bellezza? Cosa sono quegli elusivi quanti alla base della fisica contemporanea? Siamo sicuri che l'aritmetica non ci inganni? Peter Atkins offre una guida chiara e completa all'impresa scientifica, seguendo la via indicata dal dito di Galileo.

  13. Increasing Diversity in the Earth Sciences (IDES) - An Oregon Effort

    Science.gov (United States)

    de Silva, S. L.; Duncan, R. A.; Wright, D. J.; de Silva, L.; Guerrero, E. F.

    2011-12-01

    The IDES (Increasing Diversity in Earth Sciences) Program is the first partnership of its kind in the state of Oregon targeted at broadening participation in the Earth Science enterprise. Funded by the National Science Foundation Opportunities to Enhance Diversity in the Geosciences program (NSF-OEDG), this partnership involves community colleges, a research university with major strengths in Earth Science research and education and an institutionalized commitment to enhancing diversity, state and federal agencies, centers of informal education, and the Oregon Space Grant Consortium, IDES has two integrated goals: 1) to increase the number of students from under-represented groups who pursue careers in Earth Science research and education, and 2) to strengthen the understanding of Earth Sciences and their relevance to society among broad and diverse segments of the population. Built around the best practices of tiered mentoring, interactive student cohort, research and education internships, and financial support, this 4-year program recruits 10 to 12 students (mainly rising juniors) each year from science majors at Oregon State University and five Oregon community colleges. The program is reaching its goals by: a) training participants in the application of geospatial to Earth Science problems of personal relevance b) immersing participants in a two-year mentored research project that involves summer internships with academic units, state and federal agencies, and centers for informal education in Oregon. c) exposing, educating, and involving participants in the breadth of Earth Science careers through contact with Earth Science professionals through mentors, a professional internship, and a learning community that includes a speaker series. d) instilling an understanding of context and relevance of the Earth Science Enterprise to the participants, their families, their communities, and the general public. We report on the first two years of this program during

  14. ABC's of monitoring federal tax exemption.

    Science.gov (United States)

    Sanborn, A B; MacKelvie, C F

    1988-10-01

    Congress and the Internal Revenue Service (IRS) are taking a close look at the Internal Revenue Code (IRC) as it applies to Catholic institutions' activities. Although most Catholic institutions' exempt status is secured by reserved power organizational characteristics, it would behoove healthcare leaders to become familiar with the tax system and the IRS operation and, if necessary, make appropriate accommodations. They should understand what triggers an IRS audit and the audit process itself. The IRS subjects exempt institutions to organizational and operational tests. It deems that a healthcare entity is organized exclusively for an exempt (and charitable) purpose when that entity's articles of incorporation: 1. Limit the organization's purposes to charitable purposes. 2. Limit the organizations's activities to those which further its exempt purposes only, with other purposes furthered in only an insubstantial way. 3. Limit activities to those specified in IRC Section 501(c)(3). 4. Limit distribution of the organization's assets on dissolution to another organization with a like or similar exempt purpose. 5. Limit legislative and bar political activities Although most Catholic healthcare entities are "tax managed" conservatively, from an operational perspective, they often enter into transactions that the IRS considers "red flags." Some of these "red flag" transactions involve: Joint venture operations. Physician recruitment and physician handling plans. Rental/lease arrangements. Defined compensation plans. Hospital productivity plans. Profit-sharing plans. Contingent compensation arrangements. Acquisition, mergers, and divestitures. Taxable subsidiaries and unrelated business income.

  15. Streptococcus pyogenes Infection and the Human Proteome with a Special Focus on the Immunoglobulin G-cleaving Enzyme IdeS.

    Science.gov (United States)

    Karlsson, Christofer A Q; Järnum, Sofia; Winstedt, Lena; Kjellman, Christian; Björck, Lars; Linder, Adam; Malmström, Johan A

    2018-06-01

    Infectious diseases are characterized by a complex interplay between host and pathogen, but how these interactions impact the host proteome is unclear. Here we applied a combined mass spectrometry-based proteomics strategy to investigate how the human proteome is transiently modified by the pathogen Streptococcus pyogenes , with a particular focus on bacterial cleavage of IgG in vivo In invasive diseases, S. pyogenes evokes a massive host response in blood, whereas superficial diseases are characterized by a local leakage of several blood plasma proteins at the site of infection including IgG. S. pyogenes produces IdeS, a protease cleaving IgG in the lower hinge region and we find highly effective IdeS-cleavage of IgG in samples from local IgG poor microenvironments. The results show that IdeS contributes to the adaptation of S. pyogenes to its normal ecological niches. Additionally, the work identifies novel clinical opportunities for in vivo pathogen detection. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  16. Erisipelóide de Baker-Rosenbach

    Directory of Open Access Journals (Sweden)

    Aureo Guimarães de Macedo

    1970-10-01

    Full Text Available O erisipelóide de Baker-Rosenbach, embora assinalado no Brasil há 23, anos, por Sebastião Sampaio, seguido de nove casos estudados em 1951 por Lacaz e Ancona Lopes, não tem sido motivo de publicações posteriores. O A. teve ocasião de estudar seis casos, senão que três foram motivo de trabalho anterior e foram observados em 1953. Os três restantes, um de 1965 e dois de 1967, são aqui relatados. Assinala o A. a ubiquidade do germe, o Erysipelotrix rhusiopathiae e a variedade de condições em que o homem pode infectar-se, especialmente no exercício de determinadas profissões, o que dá à doença, caráter típico de doença profissional. São os operários de fábricas de botões ou em geral os que lidam com ossos, especialmente de porco ou carneiro, os açougueiros, magarefes, salsicheiros etc. São particularmente vulneráveis os que tratam com produtos do mar, pescadores, mercadores de siris, camarões, crustáceos, peixes em geral, pela facilidade com que se podem ferir e adquirir a infecção por picada ocasional. A doença atinge numerosos animais domésticos ou não, com formas clínicas bem definidas no porco (erisipela dos porcos, no carneiro (poliartrite dos carneiros, em animais de corte e de tração, em aves domésticas ou de rapina, ratos e camundongos, além de outros numerosos roedores. Moscas hematófagas e outros insetos têm sido encontrados infectados. Nunca é demais frisar que os produtos do mar são grande fonte de infecção humana. No homem, tem a dcença em geral, caráter benigno e localizado (erisipelóide, podendo em certas circunstâncias assumir característica septicêmica como no porco, produzir endocardite, como no carneiro além de outras formas clínicas e complicações. São resumidos no texto os três casos anteriormente apresentados e bem descritos os três inéditos, que têm história clínica e evolução típicas de erisipelóide. Tratando-se de doença com características tipicamente

  17. 52 üllatust ja ideed: linnahalli kõrval avatakse välibassein

    Index Scriptorium Estoniae

    2010-01-01

    Tallinn 2011 ootussarja "52 üllatust ja ideed" raames kuni 27. augustini avatud Andra Aaloe, Aet Aderi, Flo Kasearu ja Grete Soosalu installatsioonist "Bassein", mis väljendab autorite soovi, et aktiivne linn ulatuks mereni

  18. Tallinna idee / Andres Alver, Ott Alver, Marten Kaevats ; intervjueerinud Margit Mutso ; kommenteerinud Douglas Gordon

    Index Scriptorium Estoniae

    Alver, Andres, 1953-

    2011-01-01

    17. veebruaril esitleti raamatut "Tallinna idee", mis on koostatud Eesti Kunstiakadeemia 4. kursuse arhitektuuritudengite kursuseprojektide põhjal. Tallinna teemal vestlevad tudengid Ott Alver ja Marten Kaevats ning nende juhendaja professor Andres Alver

  19. Study of surface functionalization on IDE by using 3-aminopropyl triethoxysilane (APTES) for cervical cancer detection

    Science.gov (United States)

    Raqeema, S.; Hashim, U.; Azizah, N.

    2016-07-01

    This paper presented the study of surface functionalization on IDE by using 3-Aminopropyl triethoxysilane (APTES). The DNA nanochip based interdigitated (IDE) has been proposed to optimized the sensitivity of the device due to the cervical cancer detection. The DNA nanochip will be more efficient using surface modification of TiO2 nanoparticles with 3-Aminopropyl triethoxysilane (APTES). Furthermore, APTES gain the better functionalization of the adsorption mechanism on IDE. The combination of the DNA probe and the HPV target will produce more sensitivity and speed of the DNA nanochip due to their properties. The IDE has been characterized using current-voltage (IV) measurement. This functionalization of the surface would be applicable, sensitive, selective and low cost for cervical cancer detection.

  20. Combining micro-blogging and IDE interactions to support developers in their quests

    NARCIS (Netherlands)

    Guzzi, A.; Pinzger, M.; Van Deursen, A.

    2010-01-01

    Software engineers spend a considerable amount of time on program comprehension. Although vendors of Integrated Development Environments (IDEs) and analysis tools address this challenge, current support for storing and sharing program comprehension knowledge is limited. As a consequence, developers

  1. IDE Gene Polymorphism Influences on BPSD in Mild Dementia of Alzheimer's Type

    Directory of Open Access Journals (Sweden)

    Noriko Sato

    2008-01-01

    Full Text Available Insulin degrading enzyme (IDE degrades amyloid (A, which may inhibit the accumulation of A in a brain affected with dementia of Alzheimer's type (DAT. A decrease in the activity of IDE results in changes in glucose utilization in the brain, which could affect the cognitive and psychiatric symptoms of DAT. We investigated a possible association of IDE gene polymorphism and the behavioral and psychological symptoms of dementia (BPSD in mild DAT. The genotyping for IDE and apolipoprotein E (ApoE was determined in 207 patients with mild DAT and 215 controls. The occurrence of BPSD was demonstrated using the Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD. IDE gene polymorphism is unlikely to play a substantial role in conferring susceptibility to DAT, but it may be involved in the development of affective disturbance through the course of mild DAT, regardless of the presence of an ApoE 4 allele. The present data could be the result of a small sample size. Further investigations using larger samples are thus required to clarify the correlation between IDE gene polymorphism, susceptibility to DAT, and emergence of BPSD.

  2. 46 CFR 28.60 - Exemption letter.

    Science.gov (United States)

    2010-10-01

    ... VESSELS General Provisions § 28.60 Exemption letter. (a) Types of exemptions. (1) Specific exemption means... for an exemption of either type must be in writing, have specific reasons for the request, and be sent... vessel to which any exemption applies. (e) Right of appeal. Any person directly affected by a decision or...

  3. Loss of renal SNX5 results in impaired IDE activity and insulin resistance in mice.

    Science.gov (United States)

    Li, Fengmin; Yang, Jian; Villar, Van Anthony M; Asico, Laureano D; Ma, Xiaobo; Armando, Ines; Sanada, Hironobu; Yoneda, Minoru; Felder, Robin A; Jose, Pedro A; Wang, Xiaoyan

    2018-03-01

    We hypothesised that renal sorting nexin 5 (SNX5) regulates the insulin-degrading enzyme (IDE) and, thus, circulating insulin levels. We therefore studied the dynamic interaction between SNX5 and IDE in human renal proximal tubule cells (hRPTCs), as well as in rat and mouse kidneys. The regulation of IDE by SNX5 expressed in the kidney was studied in vitro and in vivo. Snx5 or mock siRNA was added to immortalised hRPTCs (passage <20) in culture or selectively infused, via osmotic mini-pump, into the remnant kidney of uninephrectomised mice and rats. SNX5 co-localised with IDE at the plasma membrane and perinuclear area of hRPTCs and in the brush border membrane of proximal tubules of human, rat, and mouse kidneys. Insulin increased the co-localisation and co-immunoprecipitation of SNX5 and IDE in hRPTCs. Silencing SNX5 in hRPTCs decreased IDE expression and activity. Renal-selective silencing of Snx5 (SNX5 protein: 100 ± 25 vs 29 ± 10, p < 0.05 [% of control]) in C57Bl/6J mice decreased IDE protein (100 ± 13 vs 57 ± 6, p < 0.05 [% of control]) and urinary insulin excretion, impaired the responses to insulin and glucose, and increased blood insulin and glucose levels. Spontaneously hypertensive rats (SHRs) had increased blood insulin and glucose levels and decreased renal SNX5 (100 ± 27 vs 29 ± 6, p < 0.05 [% of control]) and IDE (100 ± 5 vs 75 ± 4, p < 0.05 [% of control]) proteins, compared with normotensive Wistar-Kyoto (WKY) rats. Kidney Snx5-depleted WKY rats also had increased blood insulin and glucose levels. The expression of SNX5 and IDE was decreased in RPTCs from SHRs and hypertensive humans compared with cells from normotensive volunteers, indicating a common cause for hyperinsulinaemia and hypertension. Renal SNX5 positively regulates IDE expression and function. This study is the first to demonstrate the novel and crucial role of renal SNX5 in insulin and glucose metabolism.

  4. Estudo fitoquímico de Davilla rugosa: flavonóides e terpenóides

    Directory of Open Access Journals (Sweden)

    Jorge M. David

    Full Text Available Este trabalho descreve o isolamento e caracterização de alguns metabólitos presentes nos caules de Davilla rugosa (Dilleniaceae, conhecida vulgarmente como cipó-caboclo e utilizada pela população na medicina tradicional brasileira para diversas enfermidades. O extrato hidrometanólico foi particionado entre hexano, clorofórmio e acetato de etila. Da fase hexânica foram obtidos a friedelina, sitostenona e ácido betulínico. Da fase clorofórmica foram isolados através de técnicas cromatográficas o ácido betulínico e a narigenina. Enquanto que do extrato acetato de etila foram obtidos dois outros flavonóides, quercetina e 4’-O-metil taxifolina. As substâncias tiveram suas estruturas elucidadas através da análise de dados no UV e de RMN.

  5. Estudos de cestóides de peixes do Brasil

    Directory of Open Access Journals (Sweden)

    A. Arandas Rego

    1974-01-01

    Full Text Available Os autores iniciam com este trabalho um estudo sistemático de determinação dos cestóides de peixes depositados na Coleção helmintológica do Instituto Oswaldo Cruz. São referidas ou descritas as seguintes espécies e seus hospedeiros: Schizochoerus liguloideus (Diesing, 1850 e Nesolecithus janicki Posche, 1922, ambas de Arapaima gigas (Cuvier, (piracuru; Gyrocotyle meandrica Herrera, 1946, de Callorhynchus callorhynchus (L., (quimera; Acanthobothrium dasybati Yamaguti, 1934 e Pterobothriidae não identificado, de uma arraia não determinada; três tipos larvares de trypanorrhyncha e um de Proteocephalidea, de Cynoscion striatus (Cuv. e C. leiarchus (pescadinha; Proteocephalus jandia Woodland, 1934, de um bagre não determinado. Monticellia siluri (Fuhrmann, 1916 e Amphoteromorphus praeputialis sp. n. de Cetopsis caecutiens e Nomimoscolex magna sp. n. de Pimelodus clarias (mandi.The authors start, with this note, a systematic study for determination of cestodes of fishes of the Helminthological Collection of the Instituto Oswaldo Cruz. The following species and hosts are refered and described: Schizochoerus liguloideus (Diesing, 1850 and Nesolecithus janicki poche, 1922 both of Arapaima gigas (Cuvier; Gyrocotyle meandrica Herrera, 1946 of Callorhynchus callorhynchus (L.,Acanthobothrium dasybati Yamaguti, 1934 and Pterobothriidae unidentified, of an indeterminate ray; three types of larvae of Trypanorrhyncha and type of Proteocephalidea, of Cynoscion striatus (Cuv. and C. leiarchus; Proteocephalus jandia Woodland, 1934 of an indeterminate catfish; Monticellia siluri (Furhrmann, 1916 and Amphoteromorphus praeputialis sp. n. of Cetopsis caecutiens and Nomimoscolex magna sp. n. of Pimelodus clarias.

  6. cAMP/PKA signaling pathway contributes to neuronal apoptosis via regulating IDE expression in a mixed model of type 2 diabetes and Alzheimer's disease.

    Science.gov (United States)

    Li, Huajie; Yang, Song; Wu, Jian; Ji, Lei; Zhu, Linfeng; Cao, Liping; Huang, Jinzhong; Jiang, Qingqing; Wei, Jiang; Liu, Meng; Mao, Keshi; Wei, Ning; Xie, Wei; Yang, Zhilong

    2018-02-01

    Type 2 diabetes (T2D) may play a relevant role in the development of Alzheimer's disease (AD), however, the underlying mechanism was not clear yet. We developed an animal model presenting both AD and T2D, morris water maze (MWM) test and recognition task were performed to trace the cognitive function. Fasting plasma glucose (FPG) and oral glucose tolerance test (OGTT) were determined to trace the metabolism evolution. TUNEL assay and apoptosis-related protein levels were analyzed for the detection of neuronal apoptosis. Cyclic adenosine monophosphate (cAMP) agonist bucladesine or protein kinase (PKA) inhibitor H-89 were used to determine the effects of cAMP/PKA signaling pathway on IDE expression and neuronal apoptosis. The results showed that T2D contributes to the AD progress by accelerating and worsening spatial memory and recognition dysfunctions. Metabolic parameters and glucose tolerance were significantly changed in the presence of the AD and T2D. The significantly induced neuronal apoptosis and increased pro-apoptotic proteins in mice with AD and T2D were also observed. We showed the decreased expression level of IDE and the activating of cAMP/PKA signaling pathway in AD and T2D mice. Further studies indicated that cAMP agonist decreased the expression level of IDE and induced the neuronal apoptosis in mice with AD and T2D; whereas PKA inhibitor H-89 treatment showed the completely opposite results. Our study indicated that, in the T2D and AD mice, cAMP/PKA signaling pathway and IDE may participate in the contribute role of T2D in accelerating the pathological process of AD via causing the accumulation of Aβ and neuronal apoptosis. © 2017 Wiley Periodicals, Inc.

  7. Resignation from the VAT exemption of sales of residential premises by the developer

    Directory of Open Access Journals (Sweden)

    Joanna Koziollek

    2016-09-01

    Full Text Available Tax institutions should be construed in a rational manner, in order so as to not restrict economic turnover excessively. The regulations concerning the possibility to resign from the VAT exemption of sales of residential premises by the developer characterizes by the high level of formalism which affects in a negative manner the sales process performed by the developer. This paper is devoted to the fragment of the polish Act on the goods and services tax governing the issue of resignation from the VAT exemption of sales of residential premises, which implies in a certain extent to appeal to the regulation of exemptions stipulated in this Act. The subject matter of this analysis is to examine the correctness of transposition of the Directive 112 into polish legal system in the field of real estate exemptions from VAT, the conditions for exercising the optional exemption, as well as the benefit of the resignation from the VAT exemption by the taxpayer.

  8. 29 CFR 541.708 - Combination exemptions.

    Science.gov (United States)

    2010-07-01

    ... DELIMITING THE EXEMPTIONS FOR EXECUTIVE, ADMINISTRATIVE, PROFESSIONAL, COMPUTER AND OUTSIDE SALES EMPLOYEES..., professional, outside sales and computer employees may qualify for exemption. Thus, for example, an employee...

  9. Curdlan: an important microbial hydrocolloid/ Goma curdlana: um importante hidrocolóide microbiano

    Directory of Open Access Journals (Sweden)

    Elaine Soares Amorim

    2003-05-01

    Full Text Available The use of gums in the food industry is mainly based in its functional properties, which are related to the capacity to prevent or delay a series of physicals phenomenon, having an important role in the stability of many industrialized food. The use of these in the several food productions is indispensable, because they contribute to thickening, gelling, stabilization, suspension, film formation and gums can act as auxiliary agents of processing. Therefore, our objective was evaluated the chemistries physical properties, as well as, the areas of application of the microbial hydrocolloid, curdlan.O uso das gomas na indústria de alimentos baseia-se principalmente no aproveitamento de suas propriedades funcionais, que estão relacionadas à capacidade de prevenir ou retardar uma série de fenômenos físicos, desempenhando papel importante na estabilidade de muitos alimentos industrializados. É indispensável o uso destas na produção de diversos produtos alimentícios, pois contribuem para o espessamento, gelificação, estabilização, suspensão, formação de filme e podem atuar como agentes auxiliares de processamento. Desta forma, o presente trabalho buscou avaliar as propriedades físico-químicas, bem como, as áreas de aplicação da goma curdlana que é um hidrocolóide de origem microbiana.

  10. IDE PERILAKU DAN APRESIASI MASYARAKAT PONTIANAK TERHADAP UNIFIKASI KALENDER HIJRIAH

    Directory of Open Access Journals (Sweden)

    Muhammad Hasan

    2015-08-01

    لتقدير لإثبات الحكومة لبداية شهر رمضان، وشوال، وذي الحجة في مجتمع بونتياناك. لتحقيق أهداف البحث، استخدمت أساليب البحث الوصفي التفسيري. هو المجتمع بونتياناك مع عينة من 250 شخصا. وقد تم تحليل أداة جمع البيانات في شكل استبيان مع الإحصاء الوصفي وPLS. نتائج الدراسة أن معدل مستوى مشاركة هذه الفكرة 13.78 من المستوى الأدنى 7 والمستوى الأقصى 20. وأما السلوك, فأعلى قيمته معدل 15.91 من المستوى الأدنى 6 والمستوى الأقصى 20. وأما التقدير لاثبات الحكومة، فالمشاركة في اتباعه 11,26 من من المستوى الأدنى 3 والمستوى الأقصى 12. وأما من حيث مساهمة التأثير, فالفكرة لها تأثير 4.6776٪ على السلوك واما الفكرة والسلوك فلهما تأثير 3.4765٪. للتقدير في اتباع اثبات الحكومة لبداية شهر رمضان، وشوال، وذي الحجة.Abstrak: Kalender hijriah merupakan kebutuhan keagamaan dan kemasyarakatan. Karena itu, diperlukan penanggalan hijriah yang bisa menyatukan umat Islam. Penelitian ini diangkat karena tertarik terhadap fenomena di Pontianak. Pada satu sisi diinginkan adanya kesatuan penanggalan hijriah, tetapi pada sisi lain, masih terdapat keragaman tanggapan terhadap keputusan pemerintah dalam memulai ibadah puasa Ramadhan, Idul Fitri, dan Idul Adha. Karena itu, penelitian ini bertujuan untuk mendeskripsikan dan menguji pengaruh ide/persepsi, dan perilaku terhadap apresiasi mengikuti keputusan pemerintah dalam memulai Ramadhan, Syawal, dan Zulhijjah pada masyarakat Pontianak. Untuk mencapai tujuan penelitian digunakan metode deskriptif-eksplanatif. Populasi adalah masyarakat Pontianak dengan sampel sebesar 250

  11. Development of internal dose calculation model and the data base updated IDES (Internal Dose Estimation System)

    International Nuclear Information System (INIS)

    Hongo, Shozo; Yamaguchi, Hiroshi; Takeshita, Hiroshi; Iwai, Satoshi.

    1994-01-01

    A computer program named IDES is developed by BASIC language for a personal computer and translated to C language of engineering work station. The IDES carries out internal dose calculations described in ICRP Publication 30 and it installs the program of transformation method which is an empirical method to estimate absorbed fractions of different physiques from ICRP Referenceman. The program consists of three tasks: productions of SAF for Japanese including children, productions of SEE, Specific Effective Energy, and calculation of effective dose equivalents. Each task and corresponding data file appear as a module so as to meet future requirement for revisions of the related data. Usefulness of IDES is discussed by exemplifying the case that 5 age groups of Japanese intake orally Co-60 or Mn-54. (author)

  12. Interdigitated electrode (IDE) for porcine detection based on titanium dioxide (TiO_2) thin films

    International Nuclear Information System (INIS)

    Nordin, N.; Azizah, N.; Hashim, U.

    2016-01-01

    Interdigited Electrode (IDE) porcine detection can be accomplished to authenticate the halal issue that has been a concern to Muslim not only in Malaysia but all around the world. The method used is photolithography that used the p-type photoresist on the spin coater with 2500 rpm. Bare IDEs device is deposited with Titanium Dioxide (TiO_2) to improve the performance of the device. The result indicates that current-voltage (I-V) measurement of porcine probe line slightly above porcine target due to negative charges repelled each other. The IDE device can detect the porcine presence in food as lowest as 1.0 µM. Better performance of the device can be achieved with the replacement of gold deposited to trigger more sensitivity of the device.

  13. Interdigitated electrode (IDE) for porcine detection based on titanium dioxide (TiO2) thin films

    Science.gov (United States)

    Nordin, N.; Hashim, U.; Azizah, N.

    2016-07-01

    Interdigited Electrode (IDE) porcine detection can be accomplished to authenticate the halal issue that has been a concern to Muslim not only in Malaysia but all around the world. The method used is photolithography that used the p-type photoresist on the spin coater with 2500 rpm. Bare IDEs device is deposited with Titanium Dioxide (TiO2) to improve the performance of the device. The result indicates that current-voltage (I-V) measurement of porcine probe line slightly above porcine target due to negative charges repelled each other. The IDE device can detect the porcine presence in food as lowest as 1.0 µM. Better performance of the device can be achieved with the replacement of gold deposited to trigger more sensitivity of the device.

  14. IDES-EDU: Comprehensive multidisciplinary education programme to accelerate the implementation of EPBD in Europe

    DEFF Research Database (Denmark)

    Wyckmans, Annemie; Almeida, Manuela; Brunsgaard, Camilla

    are expected learning outcomes, level of integration in existing curricula and alignment with theory and assessment methods. Measures for improvement as well as further dissemination to other European educational facilities are proposed. In this manner, the project will contribute to make the multiple......This paper presents a new education and training programme on integrated energy design developed by fifteen European universities collaborating within the IDES-EDU project (2010-2013), funded by Intelligent Energy Europe. IDES-EDU aims to accelerate the implementation of the Energy Performance...... of Buildings Directive (EPBD) by proposing Master and Post Graduate education and training in multidisciplinary teams. To speed up transition from traditional, sub-optimised building projects with discipline-oriented, segregated budgets and operations, IDES-EDU developed comprehensive, multidisciplinary...

  15. Isolamento biomonitorado de alcalóides tóxicos de Prosopis juliflora (algaroba

    Directory of Open Access Journals (Sweden)

    I.M. Tabosa

    Full Text Available Uma investigação fitoquímica das vagens de Prosopis juliflora cultivada na região semi-árida do Estado da Paraíba e monitorada através de testes farmacológicos levou ao isolamento, purificação e identificação do alcalóide principal juliprosopina. A presença de outros constituintes químicos em mistura, tais como juliprosina e juliprosineno, foi verificada na fração dos alcalóides totais através de uma análise do espectro de RMN de 13C. Este trabalho sugere que a toxicidade, observada em animais de laboratório, está quimicamente relacionada com os alcalóides piperidínicos presentes nas vagens desta leguminosa.

  16. Carcinoma bilateral do plexo coróide operado com sucesso

    Directory of Open Access Journals (Sweden)

    Gilberto M. de Almeida

    1970-06-01

    Full Text Available Os autores não encontraram na literatura caso de carcinoma bilateral do plexo coróide operado com sucesso. O trabalho consta da apresentação de uma criança de 11 anos com carcinoma dos plexos coróides nos dois ventrículos laterais. São feitas considerações a respeito das dificuldades no diagnóstico, da importância dó estudo angiográfico completo e do tratamento

  17. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    OpenAIRE

    Gabriela Soncini Pasetto; Henrique Pedroso de Freitas; Carina Graziottin Colossi; Manuel Augusto Pereira Vilela

    2013-01-01

    OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9%) foram incluídos no estudo. ...

  18. 40 CFR 180.1159 - Pelargonic acid; exemption from the requirement of tolerances.

    Science.gov (United States)

    2010-07-01

    ..., vats, fillers, evaporators, pasteurizers and aseptic equipment in restaurants, food service operations, dairies, breweries, wineries, beverage and food processing plants. [62 FR 28364, May 23, 1997, as amended... (CONTINUED) PESTICIDE PROGRAMS TOLERANCES AND EXEMPTIONS FOR PESTICIDE CHEMICAL RESIDUES IN FOOD Exemptions...

  19. 29 CFR 780.405 - Exemption is direct and does not mean activities are agriculture.

    Science.gov (United States)

    2010-07-01

    ... agriculture. 780.405 Section 780.405 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... EXEMPTIONS APPLICABLE TO AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture or Irrigation That Is Exempted From the Overtime Pay...

  20. Efficient construction of approximate call graphs for JavaScript IDE services

    DEFF Research Database (Denmark)

    Feldthaus, Asger; Schäfer, Max; Sridharan, Manu

    2013-01-01

    The rapid rise of JavaScript as one of the most popular programming languages of the present day has led to a demand for sophisticated IDE support similar to what is available for Java or C#. However, advanced tooling is hampered by the dynamic nature of the language, which makes any form of stat...

  1. Détermination des radionucléides dans le repas. Application aux ...

    African Journals Online (AJOL)

    40 sont des radionucléides naturels présents dans les riz, les tubercules, les bouillons et les friandises. Dans les quatre échantillons des repas du Riz analysés, les activités spécifiques en potassium-40 sont différentes. Cette différence est ...

  2. Ideed on isiksustest tähtsamad / Vilen Künnapu ; intervjueerinud Madli Maruste

    Index Scriptorium Estoniae

    Künnapu, Vilen, 1948-

    2010-01-01

    Rahvusvahelisel üritusel London Festival of Architecture esindas Eestit Vilen Künnapu oma kohaspetsiifilise objektiga "The River Bell" ehk jõekell. Installatsiooni idee sünnist ja teostamisest, arhitektuuri funktsioonist, kunsti rollist tänapäeval

  3. IDES: Interactive Data Entry System: a generalized data acquisition software package

    International Nuclear Information System (INIS)

    Gasser, S.B.

    1980-04-01

    The Interactive Data Entry System (IDES) is a software package which greatly assists in designing and storing forms to be used for the directed acquisition of data. Objective of this package is to provide a viable man/machine interface to any comprehensive data base. This report provides a technical description of the software and can be used as a user's manual

  4. Tegijad meenutavad "52 üllatust ja ideed" / Annika Maior, Ats Parve, Epp Kubu ...[jt.

    Index Scriptorium Estoniae

    2011-01-01

    Kultuuripealinna ootussarjas osalenud räägivad, kuidas idee teostamine kulges. Projektidest "Fantaasiaaed" (Annika Maior), "Camera obscura" (Ats Parve), "Tallinna bussijaam heliseb" (Epp, Kubu, Tõnis Hiiesalu), "Tänavamiimid" (Mihkel Ernits, Kaarel Väli), "Kunstijärjekord" (Flo Kasearu, Aet Ader, Grete Soosalu, Andra Aaloe)

  5. 21 ideed, millest võiks saada monument või skulptuur / Jüri Saar

    Index Scriptorium Estoniae

    Saar, Jüri, 1973-

    2008-01-01

    Tartu linnavalitsus kogus kokku 21 skulptuuride, monumentide ja mälestustahvlite ideed, et esile tõsta auväärseid kaaslinlasi ning ehitisi. Valmis dokument "Tartu linna monumentide ja skulptuuride rajamise kava aastateks 2008-2013". Kommenteerivad Tiit Kaunissaare ja Jüri Sasi

  6. Immersiivne kunst : virtuaalne reaalsus, panoraam ja ruumilise maalikunsti ideed / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2004-01-01

    Virtuaalne reaalsus, ruumilise maalikunsti ideed ja panoraam kui moodsa installatsiooni eelkäija. 19. sajandi panoraamidest. Anton von Werneri eestvõtmisel loodud Sedani lahingu (Prantsuse-Preisi sõjas 1. septembril 1870) panoraamist. Virtuaalse ruumi eelkäijad on Pompei freskod, Baldassaare Peruzzi maalitud Sala delle Prospettive ning Sacro Monte liikumine

  7. Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Aβ and insulin degradation

    Directory of Open Access Journals (Sweden)

    Castaño Eduardo M

    2008-12-01

    Full Text Available Abstract Background Insulin degrading enzyme (IDE is implicated in the regulation of amyloid β (Aβ steady-state levels in the brain, and its deficient expression and/or activity may be a risk factor in sporadic Alzheimer's disease (AD. Although IDE sub-cellular localization has been well studied, the compartments relevant to Aβ degradation remain to be determined. Results Our results of live immunofluorescence, immuno gold electron-microscopy and gradient fractionation concurred to the demonstration that endogenous IDE from brain tissues and cell cultures is, in addition to its other localizations, a detergent-resistant membrane (DRM-associated metallopeptidase. Our pulse chase experiments were in accordance with the existence of two pools of IDE: the cytosolic one with a longer half-life and the membrane-IDE with a faster turn-over. DRMs-associated IDE co-localized with Aβ and its distribution (DRMs vs. non-DRMs and activity was sensitive to manipulation of lipid composition in vitro and in vivo. When IDE was mis-located from DRMs by treating cells with methyl-β-cyclodextrin (MβCD, endogenous Aβ accumulated in the extracellular space and exogenous Aβ proteolysis was impaired. We detected a reduced amount of IDE in DRMs of membranes isolated from mice brain with endogenous reduced levels of cholesterol (Chol due to targeted deletion of one seladin-1 allele. We confirmed that a moderate shift of IDE from DRMs induced a substantial decrement on IDE-mediated insulin and Aβ degradation in vitro. Conclusion Our results support the notion that optimal substrate degradation by IDE may require its association with organized-DRMs. Alternatively, DRMs but not other plasma membrane regions, may act as platforms where Aβ accumulates, due to its hydrophobic properties, reaching local concentration close to its Km for IDE facilitating its clearance. Structural integrity of DRMs may also be required to tightly retain insulin receptor and IDE for

  8. Taxonomia de Coffea arabica L. VI: caracteres morfológicos dos haplóides

    Directory of Open Access Journals (Sweden)

    A. Carvalho

    1952-06-01

    Full Text Available No decorrer dos trabalhos de melhoramento do café em execução no Instituto Agronômico de Campinas, plantas haplóides foram encontradas nas variedades typica, bourbon, maragogipe, semperflorens, laurina, erecta, caturra e San Ramon, da espécie Coffea arabica. Todos os haplóides apresentam porte menor e fôlhas mais estreitas e mais finas do que as variedades que lhes deram origem. Apesar de as flores serem completas, nota-se esterilidade muito acentuada. Raramente se formam alguns frutos, e êstes são providos de uma única semente, motivo pelo qual as plantas haplóides são denominadas "monosperma". Os fatôres genéticos dominantes maragogipe (Mg, erecta (Er, caturra (Ct e San Ramon, bem como os gens recessivos semperflorens (sf, e laurina (lr, das variedades estudadas, manifestam-se nas plantas haplóides, de modo semelhante ao que ocorre nas plantas diplóides correspondentes. O fator para coloração bronze dos brotos novos tem dominância incompleta e, na condição heterozigota (Brbr, mostra intensidade intermediária de côr. Nas plantas haplóides contendo um só alelo Br, a côr dos brotos novos é bronze-clara. Uma única dose do fator Na, que também apresenta dominância incompleta, dando, na forma heterozigota (Nana e na presença de tt, o fenótipo conhecido por murta, manifesta-se, na forma haplóide, dando plantas semelhantes às homozigotas ttNaNa, apenas com fôlhas mais estreitas e mais finas. Chamou-se atenção para as linhas puras de café obtidas pela duplicação do número de cromosômios dos haplóides e sua aplicação nos ensaios de linhagens e na determinação das taxas de mutação. As observações realizadas na meiose da espécie C. arabica, bem como os dados das análises genéticas e as observações feitas nesses haplóides parecem indicar que, se essa espécie fôr alotetraplóide, tal origem deve ser bem antiga, comportando-se hoje a espécie C. arábica, como um diplóide normal. As plantas

  9. Sistema Endocanabinóide e Manifestações Neuropsiquiátricas

    OpenAIRE

    Moscoso, A

    2011-01-01

    Resumo: O sistema endocanabinóide caracteriza-se por ser um sistema neuromodulatório lipídico, que está envolvido em vários processos fisiológicos (sensação de apetite, dor, humor e memória). É constituído pelos seus receptores (CB1 e CB2), ligandos endógenos (AEA e 2-AG) e um sistema enzimáticos que sintetiza e degrada os endocanabinóides. Os receptores CB1, com maior expressão no sistema nervoso central, são responsáveis pelos efeitos psicotrópicos do cannabis (THC), têm a su...

  10. Síndrome carcinóide – caso clínico

    OpenAIRE

    Renata Silva; Ana Cristino; Patrícia Santos; Miguel Moura

    2017-01-01

    Os tumores carcinóides são neoplasias raras, mais frequentemente encontradas no trato gastrointestinal, responsáveis pela produção de mediadores neuroendócrinos. A síndrome carcinoide é ainda mais rara e consiste num conjunto de sintomas característicos da libertação desses mediadores na circulação sistémica. Descrevemos um caso de um doente com síndrome carcinóide como manifestação tardia de um tumor do intestino delgado com metastização hepática, alertando para a importância de incluir esta...

  11. Generating and Purifying Fab Fragments from Human and Mouse IgG Using the Bacterial Enzymes IdeS, SpeB and Kgp.

    Science.gov (United States)

    Sjögren, Jonathan; Andersson, Linda; Mejàre, Malin; Olsson, Fredrik

    2017-01-01

    Fab fragments are valuable research tools in various areas of science including applications in imaging, binding studies, removal of Fc-mediated effector functions, mass spectrometry, infection biology, and many others. The enzymatic tools for the generation of Fab fragments have been discovered through basic research within the field of molecular bacterial pathogenesis. Today, these enzymes are widely applied as research tools and in this chapter, we describe methodologies based on bacterial enzymes to generate Fab fragments from both human and mouse IgG. For all human IgG subclasses, the IdeS enzyme from Streptococcus pyogenes has been applied to generate F(ab')2 fragments that subsequently can be reduced under mild conditions to generate a homogenous pool of Fab' fragments. The enzyme Kgp from Porphyromonas gingivalis has been applied to generate intact Fab fragments from human IgG1 and the Fab fragments can be purified using a CH1-specific affinity resin. The SpeB protease, also from S. pyogenes, is able to digest mouse IgGs and has been applied to digest antibodies and Fab fragments can be purified on light chain affinity resins. In this chapter, we describe methodologies that can be used to obtain Fab fragments from human and mouse IgG using bacterial proteases.

  12. Hemorragia Subaracnóide Perimesencefálica Não-aneurismática

    Directory of Open Access Journals (Sweden)

    Atahualpa Cauê Paim Strapasson

    2008-05-01

    Full Text Available Paciente feminina de 38 anos, previamente hígida, apresentou uma dor súbita forte, em compressão, nas regiões occipital e cervical posterior, durante esforço físico. Aproximadamente 5 minutos após sentiu sensação semelhante. Na emergência, foi diagnosticada hemorragia subaracnóide (HSA. Duas angiografias cerebrais de quatro vasos realizadas posteriormente não identificaram aneurismas.

  13. 77 FR 75494 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-12-20

    ... Multiple Regression Analysis of a Poisson Process,'' Journal of American Statistical Association, June 1971... 14 applicants' case histories. The 14 individuals applied for exemptions from the vision requirement... apply the principle to monocular drivers, because data from the Federal Highway Administration's (FHWA...

  14. 77 FR 24456 - Retail Exemptions Adjusted Dollar Limitations

    Science.gov (United States)

    2012-04-24

    ... hotels, restaurants, and similar institutions without disqualifying itself for exemption from Federal... the preparation or processing produces products in normal retail quantities, and the operations are of the type that are traditionally and usually conducted at retail stores and restaurants (21 U.S.C. 661...

  15. 29 CFR 780.502 - Legislative history of exemption.

    Science.gov (United States)

    2010-07-01

    ... Employment or Agricultural Employees in Processing Shade-Grown Tobacco; Exemption From Minimum Wage and... Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS... reported to the House (see H. Rept. No. 75, 87th Cong., first sess., p. 29) was to exclude from the minimum...

  16. 42 CFR 7.6 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.6 Exemptions. State and local health departments... ministries of health of foreign governments may be exempted from paying user charges, when using biological standards or biological preparations for public health purposes. ...

  17. Composição de carotenóides de maracujá-amarelo (Passiflora edulis flavicarpa in natura

    Directory of Open Access Journals (Sweden)

    Silva Sandra Regina da

    2002-01-01

    Full Text Available A composição de carotenóides de maracujá-amarelo in natura (Passiflora edulis comercializado em Campinas, Brasil, foi avaliada utilizando-se cromatografia líquida de alta eficiência. Em todas as amostras foram encontrados os seguintes carotenóides: beta-criptoxantina, prolicopeno, cis-zeta-caroteno, zeta-caroteno, beta-caroteno e 13-cis-beta-caroteno, além de neurosporeno e gama-caroteno em alguns lotes. Em geral, os teores de carotenóides nos diversos lotes foram significativamente diferentes. Em dois dos cinco lotes analisados, o z-caroteno foi o carotenóide principal, contribuindo com 41 e 62% do total de carotenóides, enquanto que em outros dois lotes, o beta-caroteno foi o majoritário, com 55 e 74% do total e em um dos lotes o cis-zeta-caroteno esteve presente em maior concentração, com 29%. Este tipo de inversão entre os carotenóides majoritários não é comumente encontrado em frutas e vegetais.

  18. The study of concentration effects of target hybridization on cervical cancer detection using interdigitated electrodes (IDE)

    Science.gov (United States)

    Noriani, C.; Hashim, U.; Azizah, N.

    2016-07-01

    Human Papilloma Virus (HPV) is a virus from the Papilloma virus family that affects human skin and the moist membranes that line the body, such as the throat, mouth, feet, fingers, nails, anus and cervix [1]. There are over 100 types, of which 40 can affect the genital area. Most known HPV types cause no symptoms to humans. Some, however, can cause verrucae (warts), while a small number can increase the risk of developing several cancers, such as that of the cervix, penis, vagina, anus and oropharynx (oral part of the pharynx - throat cancer). HPV strand 16 and 18 are well known for causing the advanced of Cervical Cancer (CC). Currently, integrated electrodes (IDEs) are implemented in various sensing devices including surface acoustic wave (SAW) sensors, chemical sensors as well as current MEMS biosensors. IDEs have been optimized for a variety of sensing applications including biosensors sensors, acoustic sensors, and chemical sensors. However, optimization for cancer cell detection has yet to be reported. The output signal strength of IDEs is controlled through careful design of the active area, width, and spacing of the electrode fingers the efficiency of DNA nanochip depends mainly on the sequence of the capture probes and the way they are attached to the support [2]. This strategy presented a simple, rapid and sensitive platform for HPV detection and would become a powerful tool for pathogenic microorganisms screening in clinical diagnosis. The coupling procedure must be quick, covalent, and reproducible.

  19. Falha a longo prazo no tratamento do melanoma de coróide com termoterapia transpupilar

    Directory of Open Access Journals (Sweden)

    Gabriela Soncini Pasetto

    2013-08-01

    Full Text Available OBJETIVO: Avaliar, retrospectivamente, num longo intervalo de tempo, os resultados da termoterapia transpupilar em casos selecionados do melanoma de coróide. MÉTODOS: Foram identificados todos os casos com melanoma de coróide tratados com termoterapia transpupilar, como terapia única ou suplementar. Foram excluídos os casos com seguimento inferior a 60 meses, prontuários incompletos ou com o abandono do acompanhamento. RESULTADOS: De um total de 18 olhos, 7 (38.9% foram incluídos no estudo. Cinco (71,4% pacientes foram tratados exclusivamente com termoterapia transpupilar, em 1 (14,2% olho a crioterapia foi simultânea, 1 (14,2% suplementou braquiterapia - placa episcleral. Três (42.8% sofreram recorrência, 2 (28.5% apresentaram metástases (um óbito, 2 foram enucleados. Complicações foram encontradas em 3 olhos: dobras maculares em 2, hemorragia vítrea em 1. Nos olhos enucleados, não havia extensão extraescleral, porém células interesclerais foram identificadas. CONCLUSÃO: Termoterapia transpupilar mostra um declínio em sua eficácia e conserva os riscos de metástases em períodos mais longos de acompanhamento, sendo necessária uma definição mais exata de seu papel nos melanomas de coróide.

  20. Tumores de plexo coróide: estudo epidemiológico comparativo de 24 casos

    Directory of Open Access Journals (Sweden)

    Torres Luiz Fernando Bleggi

    2004-01-01

    Full Text Available Tumores derivados do plexo coróide são neoplasias raras do sistema nervoso central que acometem principalmente crianças. Este estudo apresenta uma série de 38 pacientes com tumores de origem neuroectodérmica, dentre os quais 24 possuem diagnóstico histológico e/ou imunoistoquímico de Carcinoma do Plexo Coróide (CPC. Destes, 16 eram do gênero masculino. O local predominantemente acometido foi o ventrículo lateral esquerdo. As manifestações clínicas mais freqüentes foram hidrocefalia, hipertensão intracraniana e crises convulsivas. Todos os pacientes foram submetidos a tratamento cirúrgico. Houve um óbito no per-operatório e outro no pós-operatório imediato. Nove pacientes tiveram recidiva, evoluindo a óbito em tempo médio de 12,3 meses. Sete estão vivos. Os demais casos não apresentavam dados disponíveis. Em Curitiba, o CPC tem uma alta prevalência em relação a outros tumores do plexo coróide, podendo estar relacionado a algum agente patogênico.

  1. An anatomical study of the subcoracoid space Um estudo anatômico do espaço subcoracóide

    Directory of Open Access Journals (Sweden)

    Arnaldo Amado Ferreira Neto

    2006-10-01

    Full Text Available PURPOSE: To evaluate the amplitude of the subcoracoid space under maximum internal and external rotations of the humeral head and measure the distance between the apex of the coracoid process and the following anatomical structures: (a point of entry of the musculocutaneous nerve and its branches into the coracobrachial muscles and into the short head of the biceps brachii muscle; (b acromial artery; (c lesser tubercle of the humerus. METHOD: Thirty shoulders of fresh cadavers, without any kind of shoulder pathology, (9 males and 6 females were dissected, and the distances (in mm were measured between the anatomical structures defined above and the apex of the coracoid process. RESULTS: The mean distance between the apex of the coracoid process and the musculocutaneous nerve was 49.2 mm (in all specimens a proximal branch of the nerve was identified 34.2 mm away from the apex of the coracoid process, which was not significantly different between the sexes or body sides; the mean distance between the apex of the coracoid process and the acromial artery was 12.4 mm, which was not significantly different between the sexes or body sides; the mean distance between the apex of the coracoid process and the lesser tubercle of the humerus, with the humeral head under internal rotation, was 10.6 mm in men and 8.6 mm in women, values that were significantly different between the sexes. DISCUSSION: In women, the smaller distance between the apex of the coracoid process and the lesser tubercle of the humerus in the arm internal rotation suggests a higher chance of impingement between those bone structures among the female sex.OBJETIVO: Avaliar a amplitude do espaço subcoracóide em rotação máxima interna e externa da cabeça do úmero e medir a distância entre o ápice do processo coracóide e as seguintes estruturas anatômicas: (a ponto de entrada do nervo musculocutâneo e suas ramificações nos músculos coracobraquiais e na cabeça curta do m

  2. 21 CFR 1308.35 - Exemption of certain cannabis plant material, and products made therefrom, that contain...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exemption of certain cannabis plant material, and... ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE SCHEDULES OF CONTROLLED SUBSTANCES Exempt Cannabis Plant... cannabis plant material, and products made therefrom, that contain tetrahydrocannabinols. (a) Any processed...

  3. 43 CFR 24.7 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Exemptions. 24.7 Section 24.7 Public Lands...-FEDERAL RELATIONSHIPS § 24.7 Exemptions. (a) Exempted from this policy are the following: (1) The control and regulation by the United States, in the area in which an international convention or treaty...

  4. 29 CFR 2580.412-29 - Exemption.

    Science.gov (United States)

    2010-07-01

    ... Exemptions Savings and Loan Associations Subject to Federal Regulation § 2580.412-29 Exemption. An exemption... Act is granted whereby savings and loan associations (including building and loan associations... for the benefit of their own employees, where such a savings and loan association is the administrator...

  5. 20 CFR 401.85 - Exempt systems.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Exempt systems. 401.85 Section 401.85... INFORMATION The Privacy Act § 401.85 Exempt systems. (a) General policy. The Privacy Act permits certain types of specific systems of records to be exempt from some of its requirements. Our policy is to exercise...

  6. 45 CFR 5b.11 - Exempt systems.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exempt systems. 5b.11 Section 5b.11 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PRIVACY ACT REGULATIONS § 5b.11 Exempt systems. (a) General policy. The Act permits certain types of specific systems of records to be exempt from...

  7. 7 CFR 1206.43 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... exported from the United States may annually claim an exemption from the assessments required under § 1206... will handle less than 500,000 pounds of domestic mangos for the fiscal period for which the exemption... mangos during the fiscal period for which the exemption is claimed. (c) Upon receipt of an application...

  8. 7 CFR 922.110 - Container exemption.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Container exemption. 922.110 Section 922.110... COUNTIES IN WASHINGTON Container Exemption; Waivers of Inspection and Certification § 922.110 Container exemption. Whenever container limitations are effective pursuant to § 922.52, a handler may make test...

  9. Expressão citofotométrica do fator de proliferação celular ki-67 no bócio colóide e no carcinoma papilífero da tireóide

    Directory of Open Access Journals (Sweden)

    Gleim Dias de Souza

    Full Text Available OBJETIVO: Comparar a expressão citofotométrica quantitativa do fator de proliferação celular Ki-67 no bócio colóide com o do carcinoma papilífero da tireóide. MÉTODOS: Foram estudadas a expressão da proteína Ki-67, em 12 casos de bócio colóide da tireóide e 20 casos de carcinoma papilífero da tireóide. Os núcleos celulares imunomarcados foram quantificados através do software SAMBA 4000 ® e do software IMMUNO®, analisando o índice de marcagem e densidade óptica. Foi estimado o coeficiente de correlação de Spearmane e o teste não-paramétrico de Mann-Whitney. RESULTADOS: Foi rejeitada a hipótese nula para o índice de marcagem. confirmando que existe diferença significativa entre o bócio colóide e o carcinoma papilífero da tireóide, quanto ao índice de marcagem do Ki-67, que são maiores nos carcinomas papilíferos da tireóide. Não foi encontrada diferença quanto à densidade óptica. Quanto ao bócio colóide, o coeficiente de correlação estimado entre o índice de marcagem e a densidade óptica do Ki-67 foi igual a 0,78. No bócio colóide, houve associação positiva e significativa entre o índice de marcagem e a densidade ótica do Ki-67. Para o carcinoma papilífero da tireóide o coeficiente de correlação estimado entre o índice de marcagem e a densidade ótica do Ki-67 foi igual a 0,18. Não houve no carcinoma papilífero de tireóide, associação entre o índice de marcagem e a densidade ótica do Ki-67. CONCLUSÃO: A expressão citofotométrica do Ki67 no bócio colóide teve índice médio de marcação de 13,92% e densidade óptica média de 36,43; a expressão citofotométrica do Ki-67 no carcinoma papilífero teve índice médio de marcação de 38,29% e densidade óptica média de 48,07%; há maior proliferação celular no carcinoma papilífero em comparação com o bócio colóide na expressão do Ki-67.

  10. 40 CFR 166.45 - Duration of crisis exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Duration of crisis exemption. 166.45... EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.45 Duration of crisis exemption. A crisis exemption may be authorized for: (a) Only as long as is...

  11. 29 CFR 793.20 - Exclusive engagement in exempt work.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exclusive engagement in exempt work. 793.20 Section 793.20... LABOR STANDARDS ACT Workweek Application of Exemption § 793.20 Exclusive engagement in exempt work. An employee who engages exclusively in a workweek in work which is exempt under section 13(b)(9) is exempt...

  12. Expressão citofotométrica da Caspase-3 no carcinoma papilífero da tireóide e no bócio colóide

    Directory of Open Access Journals (Sweden)

    Luciana Rodrigues Queiroz de Souza

    Full Text Available OBJETIVO: Descrever a expressão citofotométrica quantitativa do marcador caspase-3 no bócio colóide e no carcinoma papilífero da tireóide e comparar a imunoexpessão entre as doenças. MÉTODOS: Realizou-se estudo imunoistoquímico da proteína caspase-3 em 17 blocos de parafina de carcinoma papilífero da tiróide e 20 de bócio colóide, através do sistema SAMBA 4000 - (Sistema de análise microscópica de busca automática, objetivando-se analisar duas variáveis: índice de marcagem e densidade óptica. RESULTADOS: Houve diferença significativa quanto ao índice de marcagem da caspase-3, entre o bócio colóide e o carcinoma papilífero, sendo maior no carcinoma, e não foi encontrada diferença significativa quanto à densidade óptica. Para o bócio colóide, o coeficiente de correlação estimado entre o índice de marcagem e a densidade óptica foi igual a 0,72, indicando assim, a rejeição da hipótese nula (p <0,001, afirmando-se que existe associação positiva e significativa entre o índice de marcagem e a densidade óptica da caspase-3. Para o carcinoma papilífero da tiróide, o coeficiente de correlação estimado entre o índice de marcagem e a densidade óptica 3 foi de 0,34. O resultado do teste estatístico indicou que não se pode afirmar que existe associação entre esses parâmetros. CONCLUSÃO: Para o bócio colóide existe associação positiva e significativa entre as duas variáveis, índice de marcagem e a densidade óptica da caspase-3, enquanto que para o carcinoma papilífero não existe essa associação. O estudo comparativo entre a análise quantitativa da caspase-3, demonstrou que a apoptose é mais evidente no carcinoma papilífero do que no bócio colóide.

  13. The Anti-TNF-α Therapy in the Rheumatoid Arthritis A Terapia Anti-TNF-α na Artrite Reumatóide

    Directory of Open Access Journals (Sweden)

    Lilian Resende Faleiro

    2011-06-01

    Full Text Available Rheumatoid arthritis is a chronic, systemic autoimmune disease of unknown etiology that involves predominantly synovial articulations, which can lead to deformity and destruction. With the progression of the disease, patients with Rheumatoid Arthritis develop inability to perform activities of daily living both as a professional, generating a significant economic impact for the patient and to society. Although the exact cause of rheumatoid arthritis remains unknown, studies conducted over the past two decades has enabled greater understanding of the pathogenesis of this disease. This knowledge has allowed the development of new therapies used to treat severe forms of the disease. The main goal of treatment is to achieve remission, however, when this can not be expected to prevent joint damage and loss of function and even reduce pain. The latest strategies for the treatment of Rheumatoid Arthritis involve the early diagnosis and aggressive control of inflammation. The recognition of pro-inflammatory cytokines expressed more as tumor necrosis factor α (TNF-α and interleukin (IL 1 and IL6 enabled developing new therapies directed against these cytokines targets. TNF-α is a proinflammatory cytokine that plays a key role in immune response, defense against microorganisms and the inflammatory process. Biological agents that inhibit TNF-α are considered effective in reducing activity and in the retardation of structural joint damage in rheumatoid arthritis, especially in forms refractory to conventional treatments. Currently, they are available in Brazil, three anti-TNF-α: infliximab, etanercept and adalimumab. These drugs are relatively safe for Rheumatoid Arthritis, but may, however, present serious infectious complications such as reactivation of latent tuberculosis.The high cost of these drugs, their use in hospital and the risk to opportunistic infections remain the limiting factors for its widespread use in the treatment of Rheumatoid

  14. Efeito de diferentes doses de flavonóides em ratos hiperlipidêmicos

    Directory of Open Access Journals (Sweden)

    OLIVEIRA Tania Toledo de

    2002-01-01

    Full Text Available O objetivo deste estudo foi avaliar o efeito de diferentes doses de baicaleína, morina, naringenina, naringina, quercetina e rutina no aumento dos níveis de colesterol-HDL e trigliceróis em ratos hiperlipidêmicos. Tais flavonóides foram administrados em 3 doses (5, 10, 15 mg/animal a ratos machos da raça Wistar, com 30 dias de vida, alimentados com dieta não purificada de fórmula da marca Labina®. A hiperlipidemia foi induzida pela administração de Triton, na dose de 300 mg/kg de peso vivo. Após 24 horas, os flavonóides foram administrados, sendo cada dose aplicada em grupos de 8 animais. Após 48 horas da aplicação do Triton, os animais foram anestesiados e, por punção cardíaca, amostras de sangue foram coletadas para realização das análises de colesterol, colesterol-HDL e triacilgliceróis no soro. Os melhores resultados para a redução do colesterol foram obtidos com os flavonóides quercetina e rutina, na dose de 5 mg, e naringenina, na dose de 10 mg. A baicaleína, nas doses de 5 e 10 mg, foi a que apresentou as menores reduções para colesterol-HDL. Já para as concentrações de triacilgliceróis, a baicaleína foi a que mais reduziu este parâmetro, independentemente da dose utilizada.

  15. Laringectomia supracricóide (chep para câncer glótico

    Directory of Open Access Journals (Sweden)

    Roberto R. M. Araújo Lima

    Full Text Available OBJETIVOS: Com a intenção de se avaliar os resultados funcionais e terapêuticos da laringectomia supracricóide com crico-hióide-epiglote-pexia (CHEP foram estudados 50 casos de pacientes com carcinoma epidermóide da glote classificados como T2/T3 submetidos a esta técnica em nossa instituição. MÉTODOS: Foi realizada uma análise retrospectiva entre 1996 e 1999. Classificamos 18 pacientes como T2N0M0 e 32 pacientes como T3N0M0. Quarenta e um pacientes foram submetidos a esvaziamento cervical seletivo lateral bilateralmente, quatro foram submetidos ao mesmo esvaziamento unilateralmente, e cinco não foram esvaziados. Analisamos as complicações e a sobrevida livre de doença pelo método de Kaplan-Meyer. RESULTADOS: Dez pacientes tiveram complicações pós-operatórias, dois foram tratados com complementação da laringectomia. Os 48 pacientes restantes mantiveram a via aérea normal, deglutição e a voz. Três pacientes no grupo submetido a esvaziamento cervical apresentaram linfonodo metastático. Quatro pacientes tiveram recidiva da doença, três com recidiva local, sendo dois tratados com laringectomia total e estão vivos e sem doença, o outro com doença avançada alcançou o óbito pela doença. O paciente que teve recidiva no pescoço foi tratado com esvaziamento cervical mais radioterapia e morreu com doença. Dois pacientes tiveram um segundo tumor primário em orofaringe, sendo um tratado com radioterapia paliativa e morreu com doença e o outro tratado com cirurgia está vivo e sem doença. A sobrevida livre de doença em três anos foi de 88% para pacientes T2 e 72% para pacientes T3. CONCLUSÕES: Esta técnica é útil no tratamento de casos selecionados de carcinoma epidermóide da glote T2/T3 sempre se considerando a extensão da doença. A incidência de complicações necessitando laringectomia total de resgate não compromete a funcionalidade desta técnica. A sobrevivência é comparável aos pacientes submetidos

  16. IDES-EDU – new interdisciplinary education program for Sustainable Buildings

    DEFF Research Database (Denmark)

    Dvorakova, Pavla; Kabele, Karel; Brunsgaard, Camilla

    2013-01-01

    Buildings fulfilling all requirements related to energy, economy and environment are necessary to be designed by interdisciplinary teams with efficient transfer of information and good knowledge base. IDES EDU is a project co-funded by the Intelligent Energy Europe program in which 15 European...... universities make a concerted effort to develop and implement balanced master and postgraduate courses on Sustainable Energy Design providing skills and knowledge that exceed the requirements of the EPBD. The resulting courses focus on different aspects of sustainable building design from the perspective...

  17. Resultados do Grupo de Trabalho de Tecnologias Avançadas IDE do Projecto OTALEX C

    OpenAIRE

    Vivas, Pedro; Álvarez, Rafael; Mateus, Júlio; Pavo, Marcos; Rubio, J.M.; González, Julián; Soriano, Marcos; Caballero, Carmen; Aparício, Alberto; Batista, T.; Carriço, Cristina; Cabezas, José; Fernández, Luis; Jiménez, Alberto; Gamero, Ulises

    2013-01-01

    Apresentam-se os resultado do Grupo de Trabalho de Tecnologias Avançadas IDE do projeto OTALEX-C, sendo estes: a geração de dados interligados de elementos geográficos do território OTALEX-C para a publicação de uma Web Semântica, e a captura e publicação de dados ambientais através de serviços padronizados de registo de observações com recurso a sensores, aplicando a standard SOS definida pela OGC. POCTEP 2007-2013

  18. Workshop on rules for exemption from regulatory control: Proceedings

    International Nuclear Information System (INIS)

    1989-04-01

    This conference report documents the proceedings of an International Workshop on the subject of exempting radiation sources and practices from regulatory control. The purpose of the workshop was to provide national regulatory authorities an opportunity to exchange information on their respective approaches and practices involving exemptions and to enhance international understanding and cooperation on the derivation and practical application of the underlying principles. In addition, input from the workshop was intended to assist the NRC in the development of a policy statement on this issue. The workshop was divided into five sessions. During the first four sessions, papers were presented which defined the relative terms and concepts, outlined the national situations and approaches to the establishment and development of exemption rules, identified and discussed the existing issues, and gave the status of the international guidelines on exemption rules. The fifth session was devoted to summarizing the workshop and identifying the areas of consensus, the outstanding issues and the areas for future work. Individual papers were processed separately for the data base

  19. 78 FR 76399 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0185] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 37 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from [[Page 76400

  20. 76 FR 9854 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0011] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  1. 78 FR 1923 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0350] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  2. 77 FR 3549 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-24

    ...-0368] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  3. 76 FR 9862 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-22

    ...-0025] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  4. 78 FR 1927 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-0351] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  5. 76 FR 64165 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-17

    ...-0277] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  6. 77 FR 533 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-05

    ...-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  7. 78 FR 38439 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  8. 78 FR 14406 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-03-05

    ...-0013] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  9. 76 FR 61140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ...-0194] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...

  10. 77 FR 40941 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-11

    ...-0163] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  11. 77 FR 46149 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-02

    ...-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  12. 77 FR 64181 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-18

    ...-0283] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  13. 78 FR 26419 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ...-0018] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  14. 77 FR 56258 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-12

    ...-0219] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  15. 78 FR 38435 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ...-0181] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  16. 76 FR 66120 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-25

    ...-0278] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  17. 78 FR 20381 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-04

    ...-0015] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  18. 77 FR 10612 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-0382] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  19. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ...-0193] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for exemption from the diabetes mellitus... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...

  20. Below regulatory concern - or simply exempt?

    International Nuclear Information System (INIS)

    Brodsky, A.

    1991-01-01

    The US Nuclear Regulatory Commission published a policy statement last summer on ''below regulatory concern'' (BRC), which exempted small quantities of radioactive material from regulatory control and would allow the deregulated disposal of some low level waste. The policy drew opposition from several groups. NRC is not planning to revise its BRC policy statement, but wants to develop a concensus on how to implement the policy. Although the Commission's publication of a long needed policy framework for guiding exemption decisions should be welcomed by those of us who have been concerned with making such decisions, there is an urgent need for further consensus building. The policy statement offers only broad guidelines, some of which could be confusing and seem contradictory. The policy statement by itself could further erode public confidence in the NRC's commitment to specific limits of risk, and the ability of its staff to independently evaluate the risks. Another reason why it is appropriate and urgent to embark upon consensus building involving all parties and the public, is that the risks of low level radioactive waste disposal as practiced and proposed in the United States have long been exaggerated in biased reports that receive most media attention. A consensus process needs to be established so that the public can have confidence that its concerns have been properly addressed. (author)

  1. Treatability study sample exemption: update

    International Nuclear Information System (INIS)

    1997-01-01

    This document is a RCRA Information Brief intended to update the information in the 1991 Small-Scale Treatability Study Information Brief, and to address questions about the waste and treatability study sample exemptions that have arisen since References 3 and 5 were published

  2. Interdigitated electrode (IDE) for porcine detection based on titanium dioxide (TiO{sub 2}) thin films

    Energy Technology Data Exchange (ETDEWEB)

    Nordin, N.; Azizah, N. [Institute of Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar Perlis (Malaysia); Hashim, U., E-mail: uda@unimap.edu.my [Institute of Electronic Engineering (INEE), Universiti Malaysia Perlis, 01000 Kangar Perlis (Malaysia); School of Microelctronic Engineering, Universiti Malaysia Perlis, 01000 Kangar Perlis (Malaysia)

    2016-07-06

    Interdigited Electrode (IDE) porcine detection can be accomplished to authenticate the halal issue that has been a concern to Muslim not only in Malaysia but all around the world. The method used is photolithography that used the p-type photoresist on the spin coater with 2500 rpm. Bare IDEs device is deposited with Titanium Dioxide (TiO{sub 2}) to improve the performance of the device. The result indicates that current-voltage (I-V) measurement of porcine probe line slightly above porcine target due to negative charges repelled each other. The IDE device can detect the porcine presence in food as lowest as 1.0 µM. Better performance of the device can be achieved with the replacement of gold deposited to trigger more sensitivity of the device.

  3. Carcinoma Papilífero da Tireóide e Tireoidite de Hashimoto: uma revisão integrativa.

    OpenAIRE

    Brito, Jonathan Ferreira; Cavalcante, Tiago Rodrigues; Maia Junior, Reginaldo

    2016-01-01

    Introdução: O Carcinoma Papilífero de Tireóide é a neoplasia maligna mais comum da glândula tireóide. Sua associação com a Tireoidite de Hashimoto é reconhecida e investigada há seis décadas e muitos fatores dessa relação permanecem inexplicados.Objetivo: Avaliar a associação entre o Carcinoma Papilífero de Tireóide e a Tireoidite de Hashimoto.Material e Métodos: Foi realizada revisão integrativa de artigos que objetivavam compreender essa relação sob qualquer aspecto, fosse ele epidemiológic...

  4. Influence of thermal conditions on successful ide (Leuciscus idus L. artificial reproduction during spawning season

    Directory of Open Access Journals (Sweden)

    Dariusz Kucharczyk

    2011-10-01

    Full Text Available Two forms of ide Leuciscus idus (L. spawners: wild-coloured and ornamental: yellow-coloured were kept at three various temperature regimes shortly before spawning at optimal temperature regimes (group 1, under natural temperature conditions (group 2 and in rapidly increasing temperature (group 3. The quality and quantity of collected semen, ovulation rate and survival rate of embryos to the eyed-egg-stage were recorded. The quality of semen from group 3 (where the temperature increased over the thermal spawning optimum was the worst (46 and 51% motility of spermatozoa for the wild-coloured and yellow form, respectively. The quantity of collected semen also was the lowest in the same groups (1.1 and 1.0 cm3 kg-1 for the wild-coloured and yellow form, respectively. Increasing the temperature to 16°C also caused a decreasing percentage of ovulated females (70% and 60% of ovulation for wild-coloured and yellow form, respectively and biological quality of eggs (48.9 and 47.8% embryo survival for wild-coloured and yellow form, respectively. Fluctuations of temperature at a level of 8-14°C (group 2 did not negatively affect spawning results, except for a longer latency time (over 44 hrs. The results suggest that the temperature regime shortly before controlled reproduction of ide plays an important role influencing reproductive success.

  5. El <i>De imaginibus caelestibus de Ibn al-Ḥātim

    Directory of Open Access Journals (Sweden)

    Oliveras, Marc

    2009-06-01

    Full Text Available K. Lippincott and D. Pingree published in 1987 a first Latin edition and English translation of the 15th bilingual Arabic-Latin <i>De imaginibus caelestibus, written originally by the Andalusian Ibn al-Ḥātim in the 10th century. The paper presented here aims to complete the preceding one with an Arabic edition, Spanish translation and some interpretations on the possible sources of talismanic imagery. In this brief astromagic treatise, Ibn al-Ḥātim focuses on twenty eight talismans, related to the lunar mansions, and their magical properties.

    En 1987 K. Lippincott y D. Pingree publicaron una primera edición latina junto a una traducción inglesa del tratado bilingüe árabo-latino del s. XV <i>De imaginibus caelestibus, escrito originariamente por el andalusí Ibn al-Ḥātim en el s. X. El trabajo que se presenta aquí pretende completar al precedente con una edición del texto árabe, su traducción al español y añadir algunas interpretaciones a las posibles fuentes de la imaginería talismánica. En este breve tratado de astromagia, Ibn al-Ḥātim se dedica principalmente a describir veintiocho talismanes, relacionados con las mansiones lunares, y sus propiedades mágicas.

  6. Lesões expansivas do plexo coróide Choroid plexus mass lesions

    Directory of Open Access Journals (Sweden)

    Ernesto Lima Araújo Melo

    2003-12-01

    Full Text Available As lesões expansivas do plexo coróide constituem um grupo bastante amplo e heterogêneo de doenças e seus simuladores. Tumores, infecções, anomalias congênitas, hemorragias, cistos e fenômenos degenerativos são alguns dos exemplos de causas de lesões expansivas do plexo coróide. No presente trabalho fizemos revisão da literatura pertinente, descrevendo os achados de imagem e ilustrando-os com alguns casos do nosso serviço. Apesar de não existir na literatura descrição de sinais patognomônicos, a avaliação criteriosa e sistemática das características das lesões pode sugerir determinada etiologia.Choroid plexus mass lesions encompass a broad and heterogeneous group of diseases and their simulators. Tumors, infections, congenital anomalies, hemorrhage, cysts and degenerative diseases are some examples of mass lesions affecting the choroid plexus. In this article we review the current literature, describing the imaging findings and illustrating choroid plexus mass lesions with some cases diagnosed at our facility. Despite the inexistence of pathognomonic signs, a careful and systematic evaluation of the imaging characteristics may suggest many etiologies.

  7. Ceratose liquenóide em um cão Lichenoid keratosis in a dog

    Directory of Open Access Journals (Sweden)

    Tatiana Mello de Souza

    2009-06-01

    Full Text Available A ceratose liquenóide é uma rara dermatopatia proliferativa descrita em humanos e cães. Nos cães, a doença caracteriza-se pelo aparecimento de placas hiperceratóticas bem circunscritas nas pinas e, menos freqüentemente, nas virilhas. Este artigo descreve um caso de ceratose liquenóide em um cão macho, Dobermann, de seis anos de idade, com lesões verrucosas e multifocais na face interna das orelhas e lesões alopécicas, hiperpigmentadas, levemente elevadas e descamativas nas axilas e virilhas, ambas com evolução de aproximadamente três meses. O diagnóstico foi realizado com base na associação entre os achados clínicos e histopatológicos.Lichenoid keratosis is a rare proliferative dermatopathy reported in human beings and dogs. In dogs the disease is characterized by well circumscribed hyperkeratotic plaques distributed in the skin of pinnae and, less frequently, in the inguinal region. This report describes a case of lichenoid keratosis in a six-year-old male Dobermann dog which had multifocal verrucous lesions in the internal aspect of the pinnae and slightly scaly, overpigmented alopecic lesions in the axillae and inguinal region; both lesions had a clinical course of approximately three months. The diagnosis was based on the association of the clinical and histopathological findings.

  8. Atrofia girata de coróide e retina : relato de caso

    Directory of Open Access Journals (Sweden)

    Oyamaguchi Emerson Kenji

    2003-01-01

    Full Text Available OBJETIVO: Relatar um caso de atrofia girata de coróide e retina com confirmação por meio da bioquímica do plasma. MÉTODO: Aferiu-se a melhor acuidade visual corrigida de ambos olhos (AO em tabela de Snellen. Foram realizados biomicroscopia do segmento anterior, refração, mapeamento de retina, angiografia fluoresceínica, campo visual e dosagem da ornitina sérica (aminoacidograma. RESULTADOS: Paciente de 22 anos, sexo feminino, cor branca, apresentando alta miopia e acuidade visual (AV 20/100 em AO. À biomicroscopia do segmento anterior apresentava catarata subcapsular posterior em AO. À oftalmoscopia foram verificadas lesões atróficas da coróide e da retina bem delimitadas em meia periferia de AO. O aminoacidograma constatou elevação correspondente ao complexo da ornitina. CONCLUSÃO: Relata-se um caso típico de atrofia girata, distrofia retiniana rara associada a hiperornitinemia.

  9. Síndrome carcinóide – caso clínico

    Directory of Open Access Journals (Sweden)

    Renata Silva

    2017-03-01

    Full Text Available Os tumores carcinóides são neoplasias raras, mais frequentemente encontradas no trato gastrointestinal, responsáveis pela produção de mediadores neuroendócrinos. A síndrome carcinoide é ainda mais rara e consiste num conjunto de sintomas característicos da libertação desses mediadores na circulação sistémica. Descrevemos um caso de um doente com síndrome carcinóide como manifestação tardia de um tumor do intestino delgado com metastização hepática, alertando para a importância de incluir esta síndrome no diagnóstico diferencial com inúmeras outras patologias benignas com sintomas semelhantes. Carcinoid tumors are rare neoplasms, most commonly found in the gastrointestinal tract and responsible for the production of neuroendocrine mediators. The carcinoid syndrome is even more rare and consists of a set of symptoms typical of the release of these mediators in bloodstream. Related a report case of the carcinoid syndrome as late manifestation of the tumors of the small intestine with hepatic metastases, to draw attention to inclusion of this syndrome in the differential diagnosis with numerous benign conditions with the same symptoms.

  10. Tabela Brasileira de Composição de Alimentos (TBCA-USP): dados de flavonóides

    OpenAIRE

    Nelaine Cardoso dos Santos

    2009-01-01

    Os flavonóides são compostos bioativos presentes em alimentos de origem vegetal. Em função de suas propriedades antioxidante, anti-inflamatória e antimicrobiana podem estar associados com o efeitos cardioprotetores e anticarcinogênicos. O conteúdo de flavonóides em alimentos brasileiros vem sendo quantificado por vários pesquisadores, entretanto essas informações estão dispersas em publicações, teses e em dados internos de laboratórios. O objetivo deste trabalho foi compilar e a avaliar a qua...

  11. Physical and chemical limnology of Ides Cove near Rochester, New York, 1970-1982

    Science.gov (United States)

    Bubeck, R.C.; Staubitz, W.W.; Weidemann, A.D.; Spittal, L.P.

    1995-01-01

    Ides Cove is a small embayment on the western shore of Irondequoit Bay near Rochester, N.Y. In 1982, alum was applied to the cove to seal the bottom sediments and thereby decrease nutrient fluxes in an effort to assess the applicability of this technique to Irondequoit Bay. Published data were used to develop a baseline analysis of the chemical and physical limnology of Ides Cove prior to the alum treatment and to provide a basis for comparison and evaluation of post-treatment data. The baseline analysis also enables evaluation of trends in the nutrient status and mixing patterns in Ides Cove since the decrease of sewage inflows and use of road salt in the Irondequoit Bay and Ides Cove drainage basins during 1970-82. Data from 1970-72 and 1979-82 were used to construct partial and full-year depth profiles of several physical properties and chemical constituents of water in the cove; comparison of these profiles indicates a significant improvement in water quality between 1970 and 1982. The diversion of sewage out of the Irondequoit Creek drainage basin in the late 1970's resulted in an 80-percent decrease in total phosphate concentration and a 50- to 60-percent decrease in nitrogen (nitrate and ammonia) concentration in the cove. Indications of decreased primary productivity are associated with these lowered nutrient concentrations. Summer Secchi-disk transparency increased from 0.6 m (meters) in 1970-72 to 1.2 m in 1980-82; peak epilimnetic dissolved oxygen levels decreased from a range of 22 to 28 mg/L (milligrams per liter) to a range of 16 to 20 mg/L; and peak epilimnetic pH decreased from greater than 9.4 to between 8.8 and 9.0. The decrease in the use of road salt in the Irondequoit basin beginning in 1974 resulted in a decrease in chloride concentration and gradient (difference between the surface and bottom con- centration). The maximum annual chloride concentration in the epilimnion decreased from the 210-to-225-mg/L range in the spring of 1971-72 to the

  12. 40 CFR 89.909 - Export exemptions.

    Science.gov (United States)

    2010-07-01

    ... Enforcement Auditing Section, Manufacturers Operations Division (6405-J), Environmental Protection Agency... comply with EPA certification regulations. (d) It is a condition of any exemption for the purpose of...

  13. Exemption from regulatory control of nuclear wastes

    International Nuclear Information System (INIS)

    1992-01-01

    The guide specifies the principles and criteria for the exemption of the low-level radioactive wastes for disposal, reuse or recycle. The basic radiation protection criteria are consistent with those given in the IAEA Safety Series No. 89. The guide allows two options for exemption: unrestricted or restricted. Unrestricted exemption is possible if the waste meets fairly strict activity levels. In case of restricted exemption, the receiver and further treatment of disposal of waste must be adequately specified and the compliance with radiation protection criteria must be analyzed. Some guidance on the methods for monitoring the activity in waste is also given. (5 refs.)

  14. Linhagens diaplóides de trigo obtidas via cultura de antera

    Directory of Open Access Journals (Sweden)

    Ramos Luis Carlos da Silva

    2000-01-01

    Full Text Available Realizaram-se quatro experimentos de campo no Estado de São Paulo, tanto em condição de sequeiro como de irrigação por aspersão, empregando o delineamento experimental de blocos casualizados, visando a comparação de 20 genótipos de trigo, sendo 18 linhagens diaplóides obtidas e dois cultivares, IAC-24 e Anahuac, quanto à produção de grãos, características agronômicas, resistência à ferrugem-da-folha e outros componentes da produção. Também estudou-se a tolerância ao alumínio em soluções nutritivas em condição de laboratório. As linhagens diaplóides 11, 12, 14, 17 e 18, originárias do cruzamento IAS-63/ALDAN "S"//GLEN/3/IAC-24, de porte baixo, com resistência ao acamamento, com ciclo precoce da emergência ao florescimento e da emergência à maturação e tolerância à toxicidade de alumínio, destacaram-se quanto à produção de grãos, considerando a média dos quatro experimentos. A linhagem 8 mostrou ser fonte genética de espiga comprida; a 15, de maior número de espiguetas por espiga; o cultivar Anahuac de maior número de grãos por espiga e por espigueta, e as linhagens 10, 11, 13, 15, 16 e 18 de grãos mais pesados. Todos os genótipos foram tolerantes à toxicidade de Al3+, exceto a linhagem 5, sendo que o cultivar Anahuac exibiu elevada sensibilidade. A técnica de obtenção de linhagens diaplóides via cultura de anteras de plantas em geração F1 de cruzamentos de trigo foi eficiente originando genótipos produtivos, com características agronômicas desejáveis e com tolerância à toxicidade de alumínio, num menor período de tempo em relação ao método convencional de melhoramento genético do Instituto Agronômico.

  15. Miopatia por corpos esferóides: relato de caso Spheroid body myopathy: case report

    Directory of Open Access Journals (Sweden)

    Rosana Hermínia Scola

    2005-06-01

    Full Text Available A miopatia por corpos esferóides é doença rara, classificada no grupo das miopatias congênitas relacionadas aos distúrbios da desmina; apresenta, em geral, origem autossômica dominante e com início dos sintomas na fase adulta. Relatamos o caso de menina de sete anos, com diparesia facial, hipotrofia e hipotonia muscular generalizadas, arreflexia profunda generalizada, força muscular proximal nos membros superiores e inferiores e distal dos membros superiores grau 3 e distal nos membros inferiores grau 1. A eletromiografia de agulha evidenciou recrutamento aumentado e potenciais de unidade motora de curta duração e baixa amplitude, caracterizando um padrão miopático. A biópsia muscular revelou padrão misto para miopatia e desinervação e presença de corpos esferóides intracitoplasmáticos compatíveis com a miopatia por corpos esferóides. No presente caso, a paciente apresentou precocemente o início dos sintomas e não há relatos de casos semelhantes na família.Spheroid body myopathy is a rare illness classified in the group of the congenital myopathies as a desmin-related neuromuscular disorder, presenting dominant autosomical origin with the beginning of the symptoms in the adult phase. We report on a seven years old girl with facial paresia, generalized muscular hypotrophy and hypotony, generalized deep areflexia, proximal upper and lower limbs muscular strengh and distal upper limbs grade 3 and distal lower limbs grade 1. Needle electromyography evidenced increased conscription and potentials of motor unit of short duration and low amplitude, characterizing a myopathic standard. The muscle biopsy disclosed mixed standard to myopathy, denervation and inclusion bodies that are consistent to spheroid body myopathy. In this case, the patient presented, in advance, early beginning of the symptoms and there are no similar cases in the family.

  16. 21 CFR 1308.34 - Exempt anabolic steroid products.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exempt anabolic steroid products. 1308.34 Section... SUBSTANCES Exempt Anabolic Steroid Products § 1308.34 Exempt anabolic steroid products. The list of compounds, mixtures, or preparations that contain an anabolic steroid that have been exempted by the Administrator...

  17. 50 CFR 648.54 - State waters exemption.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false State waters exemption. 648.54 Section 648... Atlantic Sea Scallop Fishery § 648.54 State waters exemption. (a) State eligibility for exemption. (1) A state may be eligible for a state waters exemption if it has a scallop fishery and a scallop...

  18. 40 CFR 166.49 - Public notice of crisis exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Public notice of crisis exemptions... PROGRAMS EXEMPTION OF FEDERAL AND STATE AGENCIES FOR USE OF PESTICIDES UNDER EMERGENCY CONDITIONS Crisis Exemptions § 166.49 Public notice of crisis exemptions. (a) Periodic notices. At least quarterly, the...

  19. 21 CFR 501.100 - Animal food; exemptions from labeling.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Animal food; exemptions from labeling. 501.100... (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS ANIMAL FOOD LABELING Exemptions From Animal Food Labeling Requirements § 501.100 Animal food; exemptions from labeling. (a) The following foods are exempt...

  20. 28 CFR 16.84 - Exemption of Immigration Appeals System.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Immigration Appeals System... MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.84 Exemption of Immigration...) Decisions of the Board of Immigration Appeals (JUSTICE/BIA-001). This exemption applies only to the extent...

  1. 75 FR 60862 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-10-01

    ...-2006-24015; FMCA- 2008-0106; FMCSA-2008-0174] Qualification of Drivers; Exemption Renewals; Vision.... SUMMARY: FMCSA previously announced its decision to renew the exemptions from the vision requirement in... exempt individuals from the vision requirement if the exemptions granted will not compromise safety. The...

  2. 40 CFR 90.908 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false National security exemption. 90.908... Exemption of Nonroad Engines from Regulations § 90.908 National security exemption. (a)(1) Any nonroad... defense, will be considered exempt from this part for purposes of national security. No request for...

  3. 40 CFR 92.908 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false National security exemption. 92.908... Provisions § 92.908 National security exemption. A manufacturer or remanufacturer requesting a national security exemption must state the purpose for which the exemption is required and the request must be...

  4. 14 CFR 302.310 - Exemptions on the Department's initiative.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Exemptions on the Department's initiative... and Certain Other Proceedings § 302.310 Exemptions on the Department's initiative. The Department may grant exemptions on its own initiative when it finds that such exemptions are required by the...

  5. Plexo coróide hipertrofiado (demonstrado angiogràficamente e hidrocefalia

    Directory of Open Access Journals (Sweden)

    Gilberto Machado de Almeida

    1964-12-01

    Full Text Available É discutido e mesmo pôsto em dúvida por alguns autores, o papel desempenhado pelo aumento de produção do líquido cefalorraqueano (LCR, na patogênese da hidrocefalia. No caso apresentado foram encontrados os seguintes elementos que indicam ser o aumento de produção do LCR a causa da hipertensão intracraniana: 1 hipertrofia dos plexos coróides sugerida pelas angiografias e confirmada pelo ato cirúrgico e necropsia; 2 ausência de bloqueio ao trânsito do LCR; 3 grande aumento do espaço subaracnói-deo, mais evidente ao nível das cisternas, inclusive inter-hemisférica e silviana.

  6. Tratamento das fraturas do processo odontóide Treatment of odontoid fractures

    Directory of Open Access Journals (Sweden)

    Pedro Augusto Pontin

    2011-01-01

    Full Text Available OBJETIVO: Este artigo faz a avaliação retrospectiva clínica e radiológica das fraturas do odontóide de 20 pacientes atendidos no IOT-HCFMUSP, durante o período de 2004-2010. MÉTODOS: Foi realizado a estratificação destas fraturas segundo sua classificação (AO/Anderson e D'Alonzo, perfil epidemiológico, tipo de tratamento, tempo de consolidação e complicações. RESULTADOS: Observou-se maior número de casos da fratura do odontóide em pacientes do sexo masculino (4:1, com idade entre 3ª e 4ª década de vida (60%, vítimas de quedas de altura (60% e acidentes automobilísticos (25% como principais mecanismos de trauma, e 15% dos casos apresentaram-se com déficit neurológico. A fraturas do odontóide de maior prevalência foram as do tipo II (55%, seguidas pelas fraturas do tipo III (40%. Os tratamentos mais empregados nas fraturas do tipo II e III foram, respectivamente, o cirúrgico (73% e conservador (87,5%. A consolidação ocorreu em até 16 semanas para 87,5% dos casos de tratamento cirúrgico e para 54,5% dos tratados conservadoramente. Não houve casos de pseudoartrose. CONCLUSÃO: O tratamento cirúrgico das fraturas do odontóide do tipo II apresentou resultados satisfatórios em relação ao tempo consolidação e baixa incidência de complicações, bem como o tratamento conservador destinado às fraturas do tipo III.Nivel de Evidência IV, série de casos.OBJECTIVE: This article describes a clinical and radiologic retrospective analysis of odontoid fractures in20 patients accompanied byThe IOT-HCFMUSP,from 2004 to 2010. METHODS: These fractures were stratified according to their classification (AO/Anderson andD'Alonzo, epidemiologic profile, type of treatment, time to consolidation of the fracture, and complications. RESULTS: It was observed that there was a higher number of odontoid fractures in males (4:1, between the third and fourth decades of life (60%, and that the main causes of the trauma were falling from

  7. Diagnósticos de enfermagem em adultos com leucemia mielóide aguda

    OpenAIRE

    Souza, Luccas Melo de; Gorini, Maria Isabel Pinto Coelho

    2006-01-01

    Trata-se de um estudo de casos, que objetivou identificar os Diagnósticos de Enfermagem (DE) de pacientes adultos com Leucemia Mielóide Aguda, a fim de fornecer subsídios à Sistematização da Assistência de Enfermagem. Utilizaram-se as técnicas de entrevista e observação, além da aplicação do Processo de Enfermagem. Durantes os três meses da coleta de dados, outros DEs foram encontrados através de novas buscas nos prontuários dos 6 pacientes. Os 32 DEs encontrados foram agrupados conforme a Te...

  8. Sistema endocanabinóide e neuroprotecção no sistema nervoso central

    OpenAIRE

    Oliveira, Leandro Jorge Nunes de Carvalho

    2009-01-01

    Introdução: Neuroprotecção é a estratégia terapêutica que tenta impedir ou atrasar a perda neuronal e, portanto, a evolução de uma doença. Em contraste com as terapêuticas sintomáticas, as estratégias neuroprotectoras actuam nos mecanismos patológicos subjacentes às manifestações clínicas da doença. Os canabinóides têm emergido como moléculas promissoras em neuroproteção, com potencial clínico, por serem capazes de reduzir a excitotoxicidade, o influxo de cálcio e as lesões oxidativas. São...

  9. Fatores dentais como risco para o desenvolvimento de carcinoma epidermóide de boca

    OpenAIRE

    Abdo, Evandro Neves; Pordeus, Isabela Almeida; Gomez, Ricardo Santiago; Mesquita, Ricardo Alves

    2016-01-01

    Os autores apresentam uma revisão da literatura sobre a participação dos fatores dentais como risco para o desenvolvimento do carcinoma epidermóide de boca (CEB). O uso de próteses removíveis não tem sido correlacionado como risco. A participação de bordas irritantes de dentes e próteses removíveis não foicomprovada na literatura. Embora a má higiene bucal seja considerada como risco, a literatura considera como pouco expressiva em relação ao uso do fumo e álcool. Novos estudos são necessário...

  10. 41 CFR 128-1.8008 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Exemptions. 128-1.8008 Section 128-1.8008 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.80-Seismic Safety Program § 128-1.8008 Exemptions. The...

  11. 7 CFR 930.162 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... MICHIGAN, NEW YORK, PENNSYLVANIA, OREGON, UTAH, WASHINGTON, AND WISCONSIN Administrative Rules and Regulations § 930.162 Exemptions. (a) General. Tart cherries which are used for the purpose of new product... and/or new markets for tart cherry products. Any exemption for experimental work shall be limited in...

  12. 23 CFR 750.503 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... services offered at the same enterprise in the defined area in the interest of the traveling public that...) requested for exemption, a listing of signs to be exempted, their location, and the name of the enterprise advertised on May 5, 1976. (3) The application of the requirements and method to the defined areas...

  13. 17 CFR 39.2 - Exemption.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Exemption. 39.2 Section 39.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DERIVATIVES CLEARING ORGANIZATIONS § 39.2 Exemption. A derivatives clearing organization and the clearing of agreements, contracts and...

  14. 17 CFR 37.2 - Exemption.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Exemption. 37.2 Section 37.2 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION DERIVATIVES TRANSACTION EXECUTION FACILITIES § 37.2 Exemption. Contracts, agreements or transactions traded on a derivatives transaction...

  15. 12 CFR 563g.3 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Exemptions. 563g.3 Section 563g.3 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITIES OFFERINGS § 563g.3 Exemptions. The offering circular requirement of § 563g.2 of this part shall not apply to an issuer's offer or...

  16. 38 CFR 1.582 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... Privacy Act in accordance with exemptions (j) and (k) of 5 U.S.C. 552a. (b) Exemption of Inspector General... with authorities, constitute an unwarranted invasion of personal privacy of others, disclose the... fear of reprisal, or fear of breach of promises of anonymity and confidentiality. This could compromise...

  17. 29 CFR 570.72 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Exemptions. 570.72 Section 570.72 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR... the Employment of Children Below the Age of 16 § 570.72 Exemptions. (a) Student-learners. The findings...

  18. 22 CFR 1102.8 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... enforcement investigations or prosecutions if such disclosure could reasonably be expected to risk... FREEDOM OF INFORMATION ACT § 1102.8 Exemptions. (a) 5 U.S.C. 552(b) provides that the requirements of the... under other laws. Specifically exempted from disclosure by statute, provided that the statute— (i...

  19. 7 CFR 1230.102 - Exemption.

    Science.gov (United States)

    2010-01-01

    ... documentation to the Board and request an exemption from assessment on 100 percent organic porcine animals or... percent organic porcine animals or pork and pork products bearing this HTS classification assigned by the... for exemption. Reasons for conventional sales include lack of demand for organic products, isolated...

  20. 48 CFR 2804.506 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Exemptions. 2804.506 Section 2804.506 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General ADMINISTRATIVE MATTERS Electronic Commerce in Contracting 2804.506 Exemptions. Pursuant to FAR 4.506(b), all...

  1. 7 CFR 985.58 - Exempt oil.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Exempt oil. 985.58 Section 985.58 Agriculture... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Order Regulating Handling Volume Limitations § 985.58 Exempt oil. Oil held by a producer or handler on the effective date of this subpart shall not be...

  2. 11 CFR 1.14 - Specific exemptions.

    Science.gov (United States)

    2010-01-01

    ... to refer apparent violations of the Act to the Attorney General or other law enforcement authorities... 11 Federal Elections 1 2010-01-01 2010-01-01 false Specific exemptions. 1.14 Section 1.14 Federal Elections FEDERAL ELECTION COMMISSION PRIVACY ACT § 1.14 Specific exemptions. (a) No individual, under the...

  3. 5 CFR 1304.4606 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Exemptions. 1304.4606 Section 1304.4606 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES POST EMPLOYMENT CONFLICT OF INTEREST § 1304.4606 Exemptions. (a) General. (1) Communications made solely to furnish scientific or...

  4. Reasons Parents Exempt Children from Receiving Immunizations

    Science.gov (United States)

    Luthy, Karlen E.; Beckstrand, Renea L.; Callister, Lynn C.; Cahoon, Spencer

    2012-01-01

    School nurses are on the front lines of educational efforts to promote childhood vaccinations. However, some parents still choose to exempt their children from receiving vaccinations for personal reasons. Studying the beliefs of parents who exempt vaccinations allows health care workers, including school nurses, to better understand parental…

  5. Microangiopatia livedóide associada à síndrome do anticorpo antifosfolípide (SAF Livedoid microangiopathy associated to antiphospholipid antibody syndrome (APS

    Directory of Open Access Journals (Sweden)

    Carla Munhoz Sanches

    2005-12-01

    Full Text Available A microangiopatia livedóide é uma síndrome de hialinização segmentar crônica dos vasos da derme, de causa desconhecida, que afeta principalmente os membros inferiores. Histopatologicamente, tanto as lesões iniciais quanto as tardias são caracterizadas por infiltrado com escassas células inflamatórias, mas com importante angiogênese capilar e microtrombos, aglomerados nodulares de pequenos capilares misturados com hemácias e depósitos de hemossiderina na derme. A ausência de infiltrado perivascular suficiente ou leucocitoclasia argumenta contra vasculite, favorecendo mais um processo trombótico. A microangiopatia livedóide acomete principalmente mulheres jovens e de meia idade. Pode ser idiopática, ou estar associada a alterações na coagulação, incluindo mutação no fator V de Leiden, deficiência da proteína C, aumento na homocisteína plasmática, anormalidades na fibrinólise, ativação plaquetária e síndrome do anticorpo antifosfolípide (SAF. Nós apresentamos um caso de uma paciente com microangiopatia livedóide, associada à presença de SAF com múltiplas úlceras em membros inferiores, que só apresentou melhora clínica após a anticoagulação plena com warfarina e posterior associação com danazol. A microangiopatia livedóide pode representar uma manifestação clínica inicial de um grupo de doenças que causam vasculopatia oclusiva. Logo, todo paciente deve ser investigado para presença de anticorpo antifosfolípide ou de outra causa de trombofilia.Livedoid microangiopathy is a chronic segmental hyalinizing syndrome of dermal blood vessels, of unknown origin, that affects mainly the lower limbs. Histopathologically, both initial as well as late lesion are characterized by few inflammatory cells infiltrate, with prevalent capillary angiogenesis and microthrombi, agglomerate of small capillaries, and dermal deposits of hemosiderin. The absence of a substantial perivascular infiltrate or leukocytoclasia

  6. 45 CFR 2508.19 - What Privacy Act exemptions or control of systems of records are exempt from disclosure?

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false What Privacy Act exemptions or control of systems of records are exempt from disclosure? 2508.19 Section 2508.19 Public Welfare Regulations Relating to... ACT OF 1974 § 2508.19 What Privacy Act exemptions or control of systems of records are exempt from...

  7. Exemption values and measurements in international comparison

    International Nuclear Information System (INIS)

    Neider, R.

    1994-01-01

    Activities are developed worldwide to systematically derive exemption limits or exemption values (IAEA, ICRP, Radiation Protection Ordinance) for different applications according to uniform principles. An important step in this regard is the adoption of the new guideline of the EU Council on radiation protection. Also regarding a uniform definition of the exemption of material from nuclear installations, agreement should be reached soon in Europe. Due to different concepts of ultimate disposal of radioactive wastes, in particular low level wastes, internationally there is no prospect of a uniform regulation concerning the exemption of very low level wastes, while in Germany a corresponding recommendation has already been made by the radiation protection commission. The exemption limits valid at present are mentioned. (orig./HP) [de

  8. Carcinoma papilífero de tireóide associado à tireoidite de hashimoto: relato de caso

    Directory of Open Access Journals (Sweden)

    Inês Maria Crespo Gutierres Pardo

    2016-10-01

    Full Text Available Introdução: A tireoidite de Hashimoto é o tipo de hipotireoidismo primário adquirido de causa auto-imune mais comum em região não-carente de iodo. Já o carcinoma papilífero de tireóide é o tipo mais comum de câncer de tireóide diferenciado na infância. Embora exista controvérsia na literatura quanto à associação entre Carcinoma Papilífero de Tireoide (CPT e Tireoidite de Hashimoto (TH, vários estudos detectaram incidência aumentada deste tipo de câncer em pacientes com TH. Objetivos: relatar o caso de uma paciente pediátrica com TH que desenvolveu CPT. Metodologia: revisão de dados obtidos e analisados do prontuário médico e pesquisa bibliográfica. Relato de caso: L. P, nascida em 25/07/1999, sexo feminino, foi encaminhada ao ambulatório de endocrinologia infantil da Policlínica Municipal de Sorocaba aos 9 anos de idade, devido ao desenvolvimento precoce de características sexuais secundárias, com aparecimento de pelos pubianos e de telarca há 1 ano. Ao exame físico, constatou-se desenvolvimento puberal segundo a classificação de Tanner, M3 P3 e tireóide palpável. Através de exames laboratoriais, foi diagnosticada com tireoidite de Hashimoto. Após 2 anos de tratamento, constatou-se aumento de tireóide em USG, diagnosticado como nódulo benigno em PAAF. No entanto, após 5 anos de seguimento, foi observada a presença de nódulo maligno, identificado como carcinoma papilífero da tireóide. Paciente foi submetida à tireoidectomia total com esvaziamento paratraqueal, devido as metástases em linfonodos. Após a cirurgia a paciente evoluiu bem, sem intercorrências e sem evidências de metástases funcionantes de carcinoma diferenciado de tireóide. Conclusão: É importante que os profissionais de saúde fiquem atentos à possibilidade de associação do CPT com a TH, quando houver mudança no padrão ultrassonográfico com a presença de linfoadenopatia cervical significativa.

  9. Termoterapia transpupilar em melanoma maligno da coróide Transpupillary thermotherapy for malignant choroidal melanoma

    Directory of Open Access Journals (Sweden)

    Martha M. Motomo Chojniak

    2001-04-01

    Full Text Available Objetivo: Vários métodos vem sendo utilizados para o tratamento dos melanomas da coróide. A proposta deste trabalho preliminar é avaliar a eficácia da termoterapia transpupilar (TTT como tratamento primário de melanomas da coróide pequenos. Métodos: Foi realizado um trabalho prospectivo e não-randomizado para avaliar os aspectos clínicos, resposta do tumor, complicações e resultados visuais de pacientes portadores de melanomas da coróide pequenos (até 4,0 mm de espessura e 12 mm de diâmetro basal tratados por termoterapia transpupilar utilizando-se sucessivas aplicações de laser diodo contínuo de 810 nm. Resultados: Foram tratados 11 pacientes portadores de melanomas da coróide pequenos. O tumor era único e pigmentado em 100% dos casos. Crescimento documentado esteve presente em 5 pacientes (45,45% previamente ao tratamento e fatores de risco para crescimento ou metástase estavam presentes em todos os pacientes. O tempo de seguimento destes pacientes a partir do tratamento foi em média de 5,72 meses (3 - 8 meses. Foram utilizadas 3 sessões de laser em 5 pacientes (45,45% e 4 sessões em 6 pacientes (64,64%. As lesões apresentavam, por ocasião do diagnóstico, uma espessura média de 2,65 mm (1,85-3,86 mm, com maior diâmetro basal médio de 7,98 mm (4,2-11,33 mm. Após o tratamento, a espessura média foi de 1,83 mm (0,98-2,93 mm e o maior diâmetro basal médio foi de 6,59 mm (3,81 mm -10,67 mm. Das lesões tratadas, 100% apresentaram diminuição da altura e do máximo diâmetro basal, tendo sido a diminuição média da espessura de 0,89 mm e do máximo diâmetro basal de 1,39 mm. A acuidade visual manteve-se inalterada em 5 casos (45,45% e piorou após o tratamento em 6 casos (54,54%. Ocorreram complicações em 9 casos, tendo sido considerada complicação grave 1 caso de descolamento parcial da retina (9,09%; as outras complicações foram consideradas leves: pequenas hemorragias intra-retinianas em 7 pacientes (63

  10. Manutenção in vitro de células IDE8 em dois tipos de soro bovino In vitro maintenance of IDE8 cells using two types of bovine serum

    Directory of Open Access Journals (Sweden)

    C.V. Bastos

    2007-04-01

    Full Text Available The present study had the objective of defining the culture conditions, optimizing the maintenance and expansion of an IDE-8 cell line in Brazil, with the aim to propose its use as a model for in vitro infection and multiplication of Brazilian strains of rickettsia and other hemoparasites. The supplementation of IDE-8 cells with two distinct fetal bovine sera (a Brazilian and an imported was evaluated. Culture media were changed weekly and subcultures were carried out every 15 days. The development of cultures and subcultures was evaluated by the percentage of viability and cellular morphology. The results indicate that the imported SFB can be replaced by the Brazilian SFB one, as no significant differences (P<0.05 were seen among culture viabilities.

  11. Multicentricidade no carcinoma diferenciado da tireóide Multicentricity in the thyroid differentiated carcinoma

    Directory of Open Access Journals (Sweden)

    José Francisco Salles Chagas

    2009-02-01

    Full Text Available O tratamento cirúrgico de escolha no carcinoma diferenciado da tireóide sempre foi controverso. OBJETIVO: Analisar o acometimento tumoral do lobo contralateral da tireóide no carcinoma diferenciado, correlacionando risco e benefício com as complicações decorrentes da segunda intervenção. CASUÍSTICA E MÉTODO: Estudo retrospectivo, de 1998 a 2006, com 27 pacientes submetidos à tireoidectomia menos que total, sendo 21 lobectomias, cinco tireoidectomias subtotais e uma istmectomia. Foram analisados: gênero, idade, tipo de cirurgia, complicações, histopatológico do espécime cirúrgico e invasão do lobo contralateral. As idades variaram de 17 a 89 anos; o tipo histopatológico mais freqüente foi o carcinoma papilífero clássico (18 casos, seguido do carcinoma folicular (seis casos, do carcinoma papilífero variante folicular (dois casos e do carcinoma de células Hürthle (um caso. Vinte e um pacientes foram submetidos à totalização da tireoidectomia, 15 a 30 dias depois. RESULTADOS: A análise do lobo contralateral foi negativa para carcinoma em 16 (76,5% e positiva nos cinco restantes (23,8%. As complicações observadas foram: disfonia temporária (três casos e hipoparatireoidismo (dois casos, sendo um permanente. CONCLUSÃO: A totalização da tireoidectomia é um procedimento importante no tratamento do carcinoma bem diferenciado da tireóide pelo elevado acometimento contralateral (23,8%. A incidência de complicações é pequena.The treatment of choice for the well differentiated thyroid carcinoma has always been controversial. AIM: to analyze tumor invasion of the thyroid gland's contralateral lobe in cases of differentiated carcinoma, correlating risk/benefit with the complications of a second surgical approach. MATERIALS AND METHODS: Retrospective study, from 1998 to 2006, of 27 patients undergoing less than total thyroidectomy: lobectomy (21, subtotal thyroidectomy (5 or isthmusectomy (1. Gender, age, type of surgery

  12. Nódulos linfóides medulares Bone marrow lymphoid nodules

    Directory of Open Access Journals (Sweden)

    Silvia M. M. Magalhães

    2003-06-01

    Full Text Available A biópsia de medula óssea é parte integrante do estadiamento e seguimento de pacientes com doenças hematológicas. Nódulos linfóides são um achado comum, usualmente observados em associação com doenças inflamatórias crônicas, infecção, hemólise, síndromes mieloproliferativas e doenças auto-imunes. São, em geral, considerados reacionais. Sendo a medula óssea o sítio extranodal mais comumente envolvido nos linfomas foliculares, o diagnóstico diferencial mais importante é a infiltração medular por doença linfoproliferativa. Do ponto de vista prático, os infiltrados linfóides são, em geral, facilmente distinguíveis ao estudo histológico. Agregados reacionais são pequenos, têm bordas delimitadas, são compostos por uma população celular heterogênea e têm localização central. Nódulos malignos infiltram a medula óssea na região paratrabecular e são compostos por células clivadas. A análise imunofenotípica, utilizando um painel de anticorpos monoclonais, é capaz de definir a linhagem celular, subpopulação e estágio de diferenciação da população neoplásica, contribuindo para a confirmação do diagnóstico. Nos casos controversos, a análise molecular da proliferação linfóide pode ser útil. A monoclonalidade pode ser demonstrada pela restrição de cadeias leves ou através do rearranjo do DNA da cadeia pesada das imunoglobulinas. Idealmente, os resultados da análise molecular devem ser interpretados em conjunto com a análise morfológica e imunofenotípica. A morfologia continua sendo o padrão-ouro na avaliação da infiltração medular por linfoma folicular e as análises imunofenotípica e molecular devem ser consideradas complementares.Bone marrow trephine biopsies are an integral part of the diagnosis, staging and follow-up of patients with haematologic disorders. Lymphoid nodules are a common finding, usually reported in association with chronic inflammatory syndromes, infection

  13. Nódulo reumatóide intermetatarsal com sintomas de neuroma de Morton: diagnóstico diferencial Intermetatarsal rheumatoid node with Morton's neuroma signs: differential diagnosis

    Directory of Open Access Journals (Sweden)

    Antonio Carlos Flores dos Santos

    2004-12-01

    Full Text Available Paciente do sexo feminino, com 38 anos de idade, portadora de artrite reumatóide ( AR , com dor intermetarsal no 3º espaço, em ambos os pés, com parestesia dos 3º e 4º dedos. Operada para ressecção de massas hipoecóicas evidenciadas por ecografia. O exame anátomo-patológico definiu degeneração fibrinóide e mixóide ( nódulo reumatóide .A 38 years old female pacient, in treatment by rheumatoid arthritis (RA, with pain in the 3º intermetatarsal space and paresthesia in the 3º toe, bilateral. She was operated for resection of hipoechoicsmasses showed in echographic examination. The anatomopathologic diagnosis was fibrinoid and mixoid degeneration ( rheumatoid nodule.

  14. Carcinoma adenóide cístico: relato de caso = Adenoid cystic carcinoma: case report

    Directory of Open Access Journals (Sweden)

    Palmeiro, Mariana Reuter

    2005-01-01

    Full Text Available O carcinoma adenóide cístico é uma neoplasia maligna rara de crescimento lento, caracterizado prognóstico reservado, devido a sua agressividade e grande potencial recidivante. A lesão é mais prevalente em pacientes na faixa etária entre 50 e 70 anos, sendo incomum em jovens. O artigo relata um caso de carcinoma adenóide cístico de glândulas salivares menores localizado no palato duro em pacientes com 26 ano, do sexo masculino que foi encaminhado para tratamento no Serviço de Cirurgia de Cabeça e Pescoço

  15. THE INFLUENCE OF JOB SATISFACTION AND LEADERSHIP STYLE ON ORGANIZATIONAL CITIZENSHIP BEHAVIOR (STUDY AT PT IDE JAYA KREASINDO

    Directory of Open Access Journals (Sweden)

    Bagus Tri Pratikto

    2015-09-01

    Full Text Available The purpose of this study is : 1 To know the description of job satisfaction and the leadership style on Organizational Citizenship Behavior (Study at PT Ide Jaya Kreasindo 2 To know the effect of job satisfaction on Organizational Citizenship Behavior 3 To know the effect of the leadership style on Organizational Citizenship Behavior 4 To know the effect of job satisfaction and the leadership style on Organizational Citizenship Behavior simultaneously. Research methods using simple random sampling. Sampling technique using simple random sampling technique and of questionnaires of 77 observations from PT Ide Jaya Kreasindo’s employees using SPSS 16.0.The empirical result shows that job satisfaction and the leadership style has positive and significant effect on organizational citizenship behavior. Simultaneously test shows that job satisfaction and the leadership style effects organizational citizenship behavior.

  16. Concomitância da tireoidite de Hashimoto e o carcinoma diferenciado da tireóide

    Directory of Open Access Journals (Sweden)

    Alexandre Roberti

    Full Text Available OBJETIVO: Avaliar a associação da tireoidite auto-imune e o carcinoma diferenciado da tireóide na Santa Casa de Misericórdia de Goiânia-Goiás. MÉTODO: De 1395 tireoidectomias realizadas de 1994 a 2003, foram selecionadas 120 carcinomas diferenciados (27 foliculares e 93 papilíferos. Foram avaliadas as variáveis clínicas (idade e sexo com apresentação de freqüências e de sumários de medidas-resumo na descrição estatística. Para aferir a associação de tireoidite auto-imune e carcinoma diferenciado da tireóide em função dos achados histopatológicos, utilizou-se tabelas de contingência e análise pelo teste não paramétrico do quiquadrado de Pearson. Em todos os testes estatísticos foi adotado um nível de significância de 5% (p<0,05. RESULTADOS: 11,1% dos carcinomas foliculares e 18,3% dos carcinomas papilíferos estão associados à tireoidite auto-imune. Existe uma relação de freqüências quatro vezes maior da tireoidite auto-imune com o carcinoma diferenciado da tireóide em comparação com outras doenças tireoideanas (16,7% X 3,6%. CONCLUSÕES: Tais resultados permitem inferir que a associação entre a tireoidite auto-imune e o carcinoma diferenciado da tireóide é mais que casual, exigindo uma observação clínico-laboratorial cuidadosa nos portadores da doença auto-imune.

  17. Associação entre sintomas de insônia e artrite reumatóide em idosos

    Directory of Open Access Journals (Sweden)

    Denise Cuoghi de Carvalho Verissimo Freitas

    2013-08-01

    Full Text Available Esse estudo objetivou avaliar sintomas de insônia em idosos residentes na comunidade e sua associação com a artrite reumatóide. Estudo descritivo, de corte transversal, recorte do projeto multicêntrico Fragilidade em Idosos Brasileiros . Foram avaliados 689 idosos (68,9% mulheres, média de idade 72,2 anos utilizando-se questionário sociodemográfico e sobre condições clínicas, questões sobre sintomas de insônia (Perfil de Saúde de Nottingham e teste de rastreio para alterações cognitivas (Mini-exame do Estado Mental. Utilizou-se análise descritiva e análise de regressão logística múltipla, com nível de significância de 5%. A associação entre sintomas de insônia e artrite reumatóide manteve-se significativa na análise multivariada; outros fatores associados foram avaliação subjetiva da saúde muito ruim, não ser aposentado e apresentar depressão. Os profissionais da área da saúde devem investigar cuidadosamente a qualidade do sono noturno dos idosos acometidos por artrite reumatóide, dada sua elevada prevalência nessa população.

  18. ANALISIS PENYEBAB KEGAGALAN MENDIRIKAN USAHA BARU PADA PARA LULUSAN PROGRAM WIRAUSAHA BARU JAWA BARAT KELAS IDE BISNIS

    Directory of Open Access Journals (Sweden)

    Rida Srihadiastuti

    2018-03-01

    Full Text Available Wirausaha Baru Jawa Barat Program (WUB Jabar Program which organized by Badiklatkop Bandung, is an entrepreneurship training in 3 choices of business field, those are food-beverage, convection, and salon. Participants are divided into Ide Bisnis class, Start-up class, or Growth class. Ide Bisnis Class is for participants who do not have a business, or already have a business but not yet reached the age of 1 year. Through a survey of 237 Ide Bisnis class graduates, there were 21 people who failed in establishing their new business after participated in the program. This research aims to determine the factors that caused failure. The qualitative descriptive method used in this research. Data collection techniques with an observation of program WUB Jabar, and interviews with 7 graduates who experienced business failure, also to 5 graduates whose business is still continuing. Data analysis techniques with Miles and Huberman models. The results of this research explained that the main factor causing graduates’ new business failure is the barrier on capital because barriers on capital causing barriers on other factors. And capital factor is also the most difficult barrier to be solved by the graduates who do not experience the business failure

  19. Choroid plexus carcinoma in a cow Carcinoma de plexo coróide em um bovino

    Directory of Open Access Journals (Sweden)

    Fabiano José Ferreira de Sant'Ana

    2009-10-01

    Full Text Available A red, firm 3.5x3.0x3.0cm mass was found within the right lateral ventricle, compressing the hippocampus and thalamus of the brain of a 4-year-old cow. The pituitary was enlarged and firm. Histologically, both the brain and pituitary masses consisted of moderately pleomorphic epithelial cells arranged as rosettes or sheets supported by a delicate fibrovascular stroma. Based on anatomical localization, histopathological and immunohistochemical findings, a diagnosis of choroid plexus carcinoma with pituitary metastasis was made.Um massa vermelha e firme de 3,5x3,0x3,0cm foi observada no ventrículo lateral, comprimindo o hipocampo e tálamo do cérebro de uma vaca de quatro anos de idade. A pituitária estava aumentada de volume e firme. Histologicamente, tanto a massa do cérebro, quanto da pituitária, consistiam de células epiteliais moderadamente pleomórficas, arranjadas em rosetas ou cordões e apoiadas em um delicado estroma fibrovascular. Com base na localização anatômica e nos achados histopatológicos e imuno-histoquímicos, foi realizado um diagnóstico de carcinoma de plexo coróide com metástase para a pituitária.

  20. Exclusion, exemption, clearance European Union approach

    International Nuclear Information System (INIS)

    Janssens, A.

    1997-01-01

    The presentation overviews the following issues: Euratom Basic Safety Standards; administrative requirements; radiation protection of the population. Scope of the Standards: natural radiation sources; exclusion. Exemption; Clearance; Import of radioactive scrap metal

  1. 12 CFR 22.4 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... State-owned property covered under a policy of self-insurance satisfactory to the Director of FEMA, who publishes and periodically revises the list of States falling within this exemption; or (b) Property...

  2. 32 CFR 701.113 - PA exemptions.

    Science.gov (United States)

    2010-07-01

    ... defense or foreign policy. Note: All DOD systems of records that contain classified information... source would be held in confidence. (f) Detailed analysis of PA exemptions. A detailed analysis of each...

  3. 25 CFR 515.12 - Specific exemptions.

    Science.gov (United States)

    2010-04-01

    ... employment in an Indian gaming operation, the applicable exemption may be waived by the Commission. (c... inquiry, constitute an unwarranted invasion of privacy, reveal a sensitive investigative technique, or...

  4. 10 CFR 1004.10 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... by other statutes; confidential, commercial, and financial information; and matters involving....) are covered by this exemption; (4) Trade secrets and commercial or financial information obtained from... lawful national security intelligence investigation, information furnished by a confidential source, (v...

  5. 22 CFR 503.8 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... documents even after the litigation is closed. (f) Exemption six—Clearly unwarranted invasion of personal... privacy by a requester being able to “piece together items” or “read between the lines” information that...

  6. 18 CFR 401.112 - Exempt information.

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Public Access to Records and Information § 401.112 Exempt... unwarranted invasion of personal privacy, (4) disclose the identity of a confidential source, (5) disclose...

  7. 50 CFR 17.7 - Raptor exemption.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 2 2010-10-01 2010-10-01 false Raptor exemption. 17.7 Section 17.7....7 Raptor exemption. (a) The prohibitions found in §§ 17.21 and 17.31 do not apply to any raptor [a... permittee's possession on November 10, 1978, or as the progeny of such a raptor. (b) This section does not...

  8. Principles for the exemption of radiation sources and practices from regulatory control

    International Nuclear Information System (INIS)

    1988-01-01

    Radiation sources, including equipment and installations, which emit ionizing radiations, are potentially harmful to health and their use should therefore be regulated. Some types of radiation source, however, do not need to be subject to regulatory control, because they present such a low hazard that it would be a needless waste of time and effort to exercise control by a regulatory process and they can therefore be exempted from it. An Advisory Group Meeting was convened in Vienna in March 1988 sponsored jointly by the IAEA and NEA. This Safety Guide is the result of that meeting and represents a first international consensus on the subject of exemption principles. This document is issued as an IAEA Safety Guide since it recommends a procedure which might be followed in implementing the Basic Safety Standards (BSS) for Radiation Protection. Its purpose is to recommend a policy on exemptions from the BSS system of notification, registration and licensing. 15 refs

  9. Efeito de baixas doses de irradiação nos carotenóides majoritários em cenouras prontas para o consumo Effect of low doses of irradiation on the carotenoids in read-to-eat carrots

    Directory of Open Access Journals (Sweden)

    Keila S. Cople Lima

    2004-06-01

    Full Text Available O presente estudo teve como objetivo avaliar o efeito das baixas doses da radiação gama na concentração de carotenóides totais, alfa e beta-caroteno em cenouras minimamente processadas, durante a vida-útil. As cenouras são as principais fontes de carotenóides provitamínicos A (alfa e beta-caroteno de origem vegetal. De acordo com a Pesquisa de Orçamento Familiar (POF realizada na região Sudeste do Brasil, no grupo de raízes e tubérculos a cenoura é amplamente consumida. A estabilidade dos carotenóides varia grandemente durante o processamento e o armazenamento, dependendo de sua estrutura, temperatura, oxigênio, luz, umidade, atividade de água e presença de ácidos e metais antioxidantes e pró-oxidantes. As cenouras minimamente processadas neste experimento foram manualmente descascadas, lavadas, cortadas mecanicamente, acondicionadas em embalagens com atmosferas modificadas de 5% O2 / 10% CO2 e 21% O2 (ar sintético, tratadas com radiação ionizante gama, fonte de césio, nas doses de 0,25, 0,50, 0,75 e 1,00kGy, e armazenadas a 5°C durante 24 dias. Os carotenóides totais foram quantificados por espectrofotometria a 449nm. Para a determinação de alfa e beta-caroteno utilizou-se cromatografia líquida de alta eficiência (CLAE. Os diferentes tratamentos e o grupo controle foram, também, avaliados através das análises de cor e voláteis, por cromatografia gasosa/espectrometria de massas associada à microextração em fase sólida (CG-EM/MEFS, para estudar as perdas dos carotenóides durante o processamento.This study aims was to evaluate the effect of low doses of gamma radiation on the total carotenoids, alpha and beta-carotene content in minimally processed carrots, during the shelflife. Carrots are the mains vegetable source of carotenoids provitamin A (alpha and beta-carotene. According to the Family Budget Survey (FBS carried out in the Brazilian Southeast, within the roots and tubers group, carrots are widely

  10. 75 FR 40736 - Acetic Acid; Exemption from the Requirement of a Tolerance

    Science.gov (United States)

    2010-07-14

    ... an exemption from the requirement of a tolerance for residues of acetic acid, also known as vinegar... a maximum permissible level for residues of acetic acid, also known as vinegar. DATES: This... humans. It is also naturally produced during the fermentation process in a wide range of foods. In plants...

  11. 77 FR 23756 - Grant of Individual Exemption Involving Renaissance Technologies, LLC (Renaissance, or the...

    Science.gov (United States)

    2012-04-20

    ... process of employee turnover. As a result, according to the Applicant, the definition of ``Participant... size or educational characteristics of its employee group, as a result of the normal employee turnover... DEPARTMENT OF LABOR Employee Benefits Security Administration [Prohibited Transaction Exemption...

  12. 75 FR 80549 - FirstEnergy Nuclear Operating Company, Davis-Besse Nuclear Power Station; Exemption

    Science.gov (United States)

    2010-12-22

    ... process for determination of RT PTS , the reference temperature RT NDT , evaluated for the end of license...]F (the weld wire heat-specific chemical composition, via the methodology of RG 1.99, Revision 2... requirements. Based on the above, no new accident precursors are created by allowing an exemption to use an...

  13. 78 FR 24303 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-24

    ... exemption applications, FMCSA exempts Christopher R. Anderson (MN), Brent T. Applebury (MO), Joseph A.... Torklidson (WI), Terry R. Washa (NE), Alfred J. Williams (VA), Scott B. Wood (ND), and James L. Zore (IN...

  14. 41 CFR 109-39.107 - Limited exemptions.

    Science.gov (United States)

    2010-07-01

    ..., AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 109-39.107 Limited exemptions. The Director, Office of... exemptions from the fleet management system. ...

  15. 77 FR 3037 - Proposed Exemptions From Certain Prohibited Transaction Restrictions

    Science.gov (United States)

    2012-01-20

    ... Vol. 77 Friday, No. 13 January 20, 2012 Part II Department of Labor Employee Benefits Security... Employee Benefits Security Administration Proposed Exemptions From Certain Prohibited Transaction Restrictions AGENCY: Employee Benefits Security Administration, Labor. ACTION: Notice of Proposed Exemptions...

  16. 40 CFR 147.502 - Aquifer exemptions. [Reserved

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Aquifer exemptions. [Reserved] 147.502... (CONTINUED) STATE, TRIBAL, AND EPA-ADMINISTERED UNDERGROUND INJECTION CONTROL PROGRAMS Florida § 147.502 Aquifer exemptions. [Reserved] ...

  17. 77 FR 5873 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-06

    ...-2011-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The... diabetes exemption applications from fifteen individuals and requested comments from the public (76 FR...

  18. Cancer Treatment Measures – PPS-Exempt Cancer Hospital

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Prospective Payment System (PPS)-Exempt Cancer Hospital Quality Reporting (PCHQR) Program currently uses three cancer specific measures. The resulting PPS-Exempt...

  19. 77 FR 70530 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-11-26

    ...-0348] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice of applications for exemption from the diabetes... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  20. 77 FR 65931 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-31

    ...-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of applications from 12 individuals for exemption from the prohibition against persons with insulin-treated diabetes...

  1. THE PROBLEMS OF USING EXEMPTION ACTIVITY VALUES FOR REGULATING THE MANAGEMENT OF SEALED RADIONUCLIDE SOURCES OF GAMMA-RADIATION

    Directory of Open Access Journals (Sweden)

    A. N. Barkovsky

    2017-01-01

    Full Text Available The article focuses on the procedure for exemption of the sealed and unsealed radionuclide sources of gamma radiation from regulatory control. The contradictory nature of the existing set of exemption criteria has been noted, leading, in some cases, to paradoxical situations. It is shown that the exempt activity values determined in NRB-99/2009 and in the international basic safety standards of the IAEA are significantly overestimated (in comparison with the activity values of a point source creating the ambient dose equivalent rate of 1 μSv / h at a distance of 0.1 m for a number of the most widely used gamma-emitting radionuclides, including 22Na, 54Mn, 75Se, 152Eu and 154Eu. It is proposed to revise the current values of exempt activity, bringing them in line with the dose rate criterion for the exempt of sealed radionuclide sources of gamma radiation, and to present them with one significant digit. The corrected values of exempt activity for  seven selected radionuclides are proposed for further use in the process of revision of the national radiation safety standards.

  2. Doença de Krabbe (Leucodistrofia de células globóides

    Directory of Open Access Journals (Sweden)

    Alexandre Alencar

    1972-01-01

    Full Text Available Apresentação de um caso de "doença de KRABBE" (leucodistrofia de células globóides. Tratava-se de uma criança do sexo feminino, com 3 anos de idade. Iniciaram-se seus padecimentos com a idade de 2 anos e meio, com apatia, irritabilidade e dificuldade progressiva no falar. Ao dar entrada no hospital apresentava-se tetraplégica, com "genun recurvatum". Membros inferiores em extensão, Amaurose. Reflexos profundos exaltados. Morte após alguns mese, em caquexia. O exame anátomo-patológico mostrou desmielinização completa da substância branca cerebral, com conservação das fibras subcorticais ditas "em U". Dilatação uniforme e global do sistema ventricular. Atrofia cortical. Microscopicamente constatou-se a presença de grupos celulares especiais, constituídos por células arredondadas, volumosas, muitas vezes polinucleadas, formando grupos esparsos ou concnetradas nos espaços perivasculares. Presença no citoplasma destas células de granulações P.A.S. positivas, insolúveis nos solventes de gorduras e coráveis pelos Sudans IV e B. Esta substância P.A.S. positiva foi também encontrada nos interstícios do tecido, nos espaços perivasculares (dentro e fora de histiocitos e no interior de vasos sanguíneos. A história familiar da paciente revelou a existência de um irmão, falecido com quadro semelhante, aproximadamente na mesma idade. Quatro outros irmãos, falecidos de causas várias, também crianças, possivelmente não eram normais.

  3. 5 CFR 1631.17 - Deletion of exempted information.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Deletion of exempted information. 1631.17... Deletion of exempted information. Where requested records contain matters which are exempted under 5 U.S.C... disclosed by the Board with deletions. To each such record, the Board shall attach a written justification...

  4. 7 CFR 301.85-2b - Exempted articles. 1

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Exempted articles. 1 301.85-2b Section 301.85-2b... § 301.85-2b Exempted articles. 1 1 The articles hereby exempted remain subject to applicable restrictions under other quarantines and other provisions of this subpart. (a) The following articles are...

  5. 18 CFR 4.105 - Action on exemption applications.

    Science.gov (United States)

    2010-04-01

    ... DETERMINATION OF PROJECT COSTS Exemption of Small Hydroelectric Power Projects of 5 Megawatts or Less § 4.105... exemption of a small hydroelectric power project from provisions of Part I of the Act other than the... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Action on exemption...

  6. 22 CFR 505.13 - General exemptions (Subsection (j)).

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true General exemptions (Subsection (j)). 505.13... exemptions (Subsection (j)). (a) General exemptions are available for systems of records which are maintained by the Central Intelligence Agency (Subsection (j)(1)), or maintained by an agency which performs as...

  7. 41 CFR 101-39.106 - Unlimited exemptions.

    Science.gov (United States)

    2010-07-01

    ...-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 101-39.106 Unlimited exemptions. Unlimited exemptions from inclusion in the fleet... below. Unlimited exemptions do not preclude agencies from requesting fleet management services, if...

  8. 9 CFR 590.660 - Inspection of exempted plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Inspection of exempted plants. 590.660... Products Plants § 590.660 Inspection of exempted plants. Duly authorized representatives of the Administrator shall make such periodic inspections of exempted plants and records thereof as the Administrator...

  9. 29 CFR 2580.412-30 - Conditions of exemption.

    Science.gov (United States)

    2010-07-01

    ... BONDING RULES Exemptions Savings and Loan Associations Subject to Federal Regulation § 2580.412-30 Conditions of exemption. This exemption applies only to those savings and loan associations (including building and loan associations, cooperative banks and homestead associations) subject to regulation and...

  10. 28 CFR 16.79 - Exemption of Pardon Attorney System.

    Science.gov (United States)

    2010-07-01

    ... System (JUSTICE/OPA-001) is to enable the Justice Department to prepare reports and recommendations to... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Pardon Attorney System. 16... OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.79 Exemption of Pardon...

  11. 32 CFR 811.5 - Customers exempt from fees.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Customers exempt from fees. 811.5 Section 811.5..., DISSEMINATION, AND SALE OF VISUAL INFORMATION MATERIALS § 811.5 Customers exempt from fees. Title III of the 1968 Intergovernmental Cooperation Act (42 U.S.C. 4201, 4231, and 4233) exempts some customers from...

  12. 76 FR 20076 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2011-04-11

    ... in favor of granting a Federal vision exemption to James H. Corby, Thomas E. Moore, and John F... 23 exemption applications, FMCSA exempts, Jody L. Baker, Gary W. Balcom, Jimmie L. Blue, Ronald Cook, James H. Corby, Bobby D. Cox, Wesley M. Creamer, Gerald S. Dennis, Cleveland E. Edwards, Thomas...

  13. 75 FR 1449 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-01-11

    ...-2009-0289] Qualification of Drivers; Exemption Applications; Diabetes AGENCY: Federal Motor Carrier... decision to exempt forty-one individuals from its rule prohibiting persons with insulin-treated diabetes... notice of receipt of Federal diabetes exemption applications from forty-one individuals and requested...

  14. 78 FR 65031 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-2013-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 19 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 19 individuals and requested comments from the...

  15. 78 FR 76398 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0188] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 29 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 29 individuals and requested comments from the...

  16. 78 FR 7855 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-02-04

    ...-2012-0349] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 12 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 12 individuals and requested comments from the...

  17. 78 FR 60014 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-30

    ...-2013-0020] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 16 individuals from its rule prohibiting persons with insulin-treated diabetes... of Federal diabetes exemption applications from 16 individuals and requested comments from the public...

  18. 78 FR 50140 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-16

    ...-2013-0019] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 24 individuals from its rule prohibiting persons with insulin-treated diabetes... of Federal diabetes exemption applications from 24 individuals and requested comments from the public...

  19. 78 FR 76397 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0187] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 16 individuals from its rule prohibiting persons with insulin-treated diabetes... receipt of Federal diabetes exemption applications from 16 individuals and requested comments from the...

  20. 75 FR 1453 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-01-11

    ...; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety Administration (FMCSA), DOT. ACTION: Notice... the vision requirement in the Federal Motor Carrier Safety Regulations for 23 individuals. FMCSA has statutory authority to exempt individuals from the vision requirement if the exemptions granted will not...

  1. 7 CFR 205.101 - Exemptions and exclusions from certification.

    Science.gov (United States)

    2010-01-01

    ... is exempt from certification under subpart E of this part and from submitting an organic system plan... 7 Agriculture 3 2010-01-01 2010-01-01 false Exemptions and exclusions from certification. 205.101...) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Applicability § 205.101 Exemptions and...

  2. 40 CFR 1042.635 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false National security exemption. 1042.635... Compliance Provisions § 1042.635 National security exemption. The standards and requirements of this part and... government responsible for national defense. (b) Manufacturers may request a national security exemption for...

  3. 40 CFR 91.1008 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false National security exemption. 91.1008... Engines § 91.1008 National security exemption. (a)(1) Any marine SI engine, otherwise subject to this part... for purposes of national security. No request for exemption is necessary. (2) Manufacturers may...

  4. 40 CFR 94.908 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false National security exemption. 94.908... § 94.908 National security exemption. (a)(1) Any marine engine, otherwise subject to this part, that is... regulations in this subpart for reasons of national security. No request for this exemption is necessary. (2...

  5. 40 CFR 89.908 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false National security exemption. 89.908... Provisions § 89.908 National security exemption. (a)(1) Any nonroad engine, otherwise subject to this part... regulations for purposes of national security. No request for exemption is necessary. (2) Manufacturers may...

  6. 28 CFR 16.76 - Exemption of Justice Management Division.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Exemption of Justice Management Division. 16.76 Section 16.76 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Exemption of Records Systems Under the Privacy Act § 16.76 Exemption of Justice...

  7. 48 CFR 252.229-7002 - Customs exemptions (Germany).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Customs exemptions... of Provisions And Clauses 252.229-7002 Customs exemptions (Germany). As prescribed in 229.402-70(b), use the following clause: Customs Exemptions (Germany) (JUN 1997) Imported products required for the...

  8. 26 CFR 1.501(a)-1 - Exemption from taxation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Exemption from taxation. 1.501(a)-1 Section 1.501(a)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exempt Organizations § 1.501(a)-1 Exemption from taxation. (a) In...

  9. 48 CFR 252.229-7005 - Tax exemptions (Spain).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Tax exemptions (Spain... of Provisions And Clauses 252.229-7005 Tax exemptions (Spain). As prescribed in 229.402-70(e), use the following clause: Tax Exemptions (Spain) (JUN 1997) (a) The Contractor represents that the...

  10. 14 CFR 399.21 - Charter exemptions (except military).

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Charter exemptions (except military). 399.21 Section 399.21 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION... Authority § 399.21 Charter exemptions (except military). In deciding applications for exemptions from...

  11. 17 CFR 247.776 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in a company's securities... AND EXCHANGE COMMISSION (CONTINUED) REGULATION R-EXEMPTIONS AND DEFINITIONS RELATED TO THE EXCEPTIONS...

  12. 17 CFR 247.775 - Exemption from the definition of “broker” for banks effecting certain excepted or exempted...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption from the definition of âbrokerâ for banks effecting certain excepted or exempted transactions in investment company... (CONTINUED) REGULATION R-EXEMPTIONS AND DEFINITIONS RELATED TO THE EXCEPTIONS FOR BANKS FROM THE DEFINITION...

  13. HAMBATAN SEMANTIK DAN BUDAYA DALAM PROSES TRANSFER IDE OLEH MAHASISWA JURUSAN NON BAHASA INGGRIS DALAM PENULISAN PARAGRAF

    Directory of Open Access Journals (Sweden)

    Doddy Rusmono

    2016-05-01

    Full Text Available Abstrak. Proses transfer ide dalam bentuk tulisan yang dilakukan oleh mahasiswa jurusan ilmu perpustakaan dan informasi sebagai mahasiswa jurusan non Bahasa Inggris (SNED yang mempelajari Bahasa Inggris sebagai bahasa asing (EFL perlu diinvestigasi. Ketidakmampuan untuk menjembatani kesenjangan antara ide dalam bahasa ibu (Bahasa Inggris dengan ide dalam bahasa pembaca (Bahasa Inggris menghambat pemahaman pembaca, khususnya pembaca yang merupakan penutur asli Bahasa Inggris. Paragraf yang ditulis oleh mahasiswa SNED sebagai pembelajar Bahasa Inggris tidak dapat dipahami karena hambatan linguistik dan budaya. Sejumlah kecil mahasiswa yang membuat tulisan Bahasa Inggris dalam ujian tengah semester memperlihatkan gambaran ketidaktepatan dalam hal menyusun kalimat sehingga Bahasa Inggris mereka pada tingkatan tertentu terdengar seperti Bahasa Indonesia. Dalam hal ini kemampuan mereka untuk menggunakan Bahasa Inggris seperti layaknya bahasa Indonesia terbukti sangat rendah sehingga seorang penutur asli Bahasa Inggris yang mencoba untuk memahami ide mereka bisa salah memahaminya. Seorang pembelajar Bahasa Inggris harus memiliki kosakata yang cukup banyak dan setidaknya mengetahui aturan gramatikal seperti formulasi 9BP+3CC (Cd,Cx,Cdx dan PoS misalnya, untuk melengkapi pemahaman sebelum benar-benar dapat mengekspresikan ide dalam tulisan Bahasa Inggris yang dapat dipahami. Selain itu, pengetahuan mahasiswa tentang budaya penutur Bahasa Inggris memainkan peranan yang sangat penting untuk menghasilkan tulisan yang bagus, sebagaimana yang diungkapkan oleh seorang ahli bahasa bahwa seringkali seorang pembelajar bahasa mengetahui aturan tata bahasa tetapi tidak memiliki pengetahuan yang cukup tentang budaya penutur asli. Mahasiswa mengalami kesulitan dalam mengkomunikasikan idenya dikarenakan ekspresi suatu ide terikat oleh budaya yang merupakan entitas independen. Budaya penutur asli mempengaruhi dan membentuk perasaan, sikap, dan respons terhadap

  14. O ideário taylorista, a gestão da subjetividade e o poder pastoral Taylorist ideology, subjectivity management, and pastoral power

    Directory of Open Access Journals (Sweden)

    Bruno Eduardo Procopiuk Walter

    2013-03-01

    Full Text Available Este ensaio tem por objetivo analisar o ideário taylorista concernente à relação entre operários e gestores a partir da categoria do poder pastoral, proposta por Michel Foucault. Se o poder disciplinar incide sobre o corpo, o poder pastoral incide sobre a alma do indivíduo, implicando - por meio de técnicas confessionais - a direção de consciência. No âmbito do taylorismo, pode-se concluir, tal poder se manifesta, mas não com um sentido parhesiastico, revelando no taylorismo um processo de configuração de verdades a respeito do sujeito operário, ou trabalhador, que o coloca em condição de objeto da gestão nas relações estabelecidas entre a gestão e o operário.This essay aims to analyze the Taylorist ideology concerning the relation between laborers and managers through the pastoral power category, proposed by Michel Foucault. If the disciplinary power is focused on the body, the pastoral power is focused on the individual's soul, implying - through confessional techniques - the direction of consciousness. Under Taylorism, one may conclude, such power manifests itself, but not in a parrhesiastic sense, revealing in Taylorism a truth configuration process with regard to the working subject, or laborer, which puts him in a condition of management object in the relations established between management and laborer.

  15. IDeF-X ECLAIRs: A CMOS ASIC for the Readout of CdTe and CdZnTe Detectors for High Resolution Spectroscopy

    International Nuclear Information System (INIS)

    Gevin, O.; Baron, P.; Coppolani, X.; Delagnes, E.; Lugiez, F.; Daly, F.; Limousin, O.; Meuris, A.; Pinsard, F.; Renaud, D.

    2009-01-01

    The very last member of the IDeF-X ASIC family is presented: IDeF-X ECLAIRs is a 32-channel front end ASIC designed for the readout of Cadmium Telluride (CdTe) and Cadmium Zinc Telluride (CdZnTe) Detectors. Thanks to its noise performance (Equivalent Noise Charge floor of 33 e - rms) and to its radiation hardened design (Single Event Latch-up Linear Energy Transfer threshold of 56 MeV.cm 2 .mg -1 ), the chip is well suited for soft X-rays energy discrimination and high energy resolution, 'space proof', hard X-ray spectroscopy. We measured an energy low threshold of less than 4 keV with a 10 pF input capacitor and a minimal reachable sensitivity of the Equivalent Noise Charge (ENC) to input capacitance of less than 7e - /pF obtained with a 6 μs peak time. IDeF-X ECLAIRs will be used for the readout of 6400 CdTe Schottky mono-pixel detectors of the 2D coded mask imaging telescope ECLAIRs aboard the SVOM satellite. IDeF-X ECLAIRs (or IDeF-X V2) has also been designed for the readout of a pixelated CdTe detector in the miniature spectro-imager prototype Caliste 256 that is currently foreseen for the high energy detector module of the Simbol-X mission. (authors)

  16. IDeF-X ECLAIRs: A CMOS ASIC for the Readout of CdTe and CdZnTe Detectors for High Resolution Spectroscopy

    Science.gov (United States)

    Gevin, Olivier; Baron, Pascal; Coppolani, Xavier; Daly, FranÇois; Delagnes, Eric; Limousin, Olivier; Lugiez, Francis; Meuris, Aline; Pinsard, FrÉdÉric; Renaud, Diana

    2009-08-01

    The very last member of the IDeF-X ASIC family is presented: IDeF-X ECLAIRs is a 32-channel front end ASIC designed for the readout of Cadmium Telluride (CdTe) and Cadmium Zinc Telluride (CdZnTe) Detectors. Thanks to its noise performance (Equivalent Noise Charge floor of 33 e- rms) and to its radiation hardened design (Single Event Latchup Linear Energy Transfer threshold of 56 MeV.cm2.mg-1), the chip is well suited for soft X-rays energy discrimination and high energy resolution, ldquospace proof,rdquo hard X-ray spectroscopy. We measured an energy low threshold of less than 4 keV with a 10 pF input capacitor and a minimal reachable sensitivity of the Equivalent Noise Charge (ENC) to input capacitance of less than 7 e-/pF obtained with a 6 mus peak time. IDeF-X ECLAIRs will be used for the readout of 6400 CdTe Schottky monopixel detectors of the 2D coded mask imaging telescope ECLAIRs aboard the SVOM satellite. IDeF-X ECLAIRs (or IDeF-X V2) has also been designed for the readout of a pixelated CdTe detector in the miniature spectro-imager prototype Caliste 256 that is currently foreseen for the high energy detector module of the Simbol-X mission.

  17. Carcinoma de tireóide em crianças e adolescentes - revisão de seis casos

    Directory of Open Access Journals (Sweden)

    Daniela V. M. Szeliga

    2001-02-01

    Full Text Available Objetivo: O carcinoma de tireóide é raro em crianças, e existem aspectos controversos sobre seu manejo. Este estudo foi realizado para avaliar aspectos diagnósticos e de seguimento destes pacientes. Métodos: Foi revisada retrospectivamente a evolução clínica de seis pacientes com carcinoma de tireóide, seguidos em Unidade de Endocrinologia Pediátrica nos últimos 17 anos. Resultados: Foram encontrados seis pacientes com carcinoma de tireóide, todos do sexo feminino, com idade de 4,5 a 12 anos. Nódulo tireoidiano esteve presente na avaliação inicial em todos os casos. A ultra-sonografia e cintilografia com 131I mostraram nódulo sólido e hipocaptante em quatro pacientes. Histologicamente, quatro eram carcinomas papilíferos, e dois foliculares. Todos foram submetidos à tireoidectomia total, sendo que quatro necessitaram também dose terapêutica de 131I devido a metástases e/ou resíduo tireoidiano. Conclusão: Nossos achados confirmaram a impressão clínica de que crianças e adolescentes com carcinoma tireoidiano têm um bom prognóstico, sem haver registro de óbito neste seguimento de até 17 anos. Estes dados estão de acordo com a literatura, que mostra baixa mortalidade nestes casos.

  18. Proximal-type epithelioid sarcoma - Case report Sarcoma epitelióide tipo proximal - Relato de caso

    Directory of Open Access Journals (Sweden)

    Luciana Mendes dos Santos

    2013-06-01

    Full Text Available Epithelioid sarcoma, first described by Enzinger in 1970, is a rare soft-tissue sarcoma typically presenting as a subcutaneous or deep dermal mass in distal portions of the extremities of adolescents and young adults. In 1997, Guillou et al. described a different type of epithelioid sarcoma, called proximal-type epithelioid sarcoma, which is found mostly in the pelvic and perineal regions and genital tracts of young to middle-aged adults. It is characterized by a proliferation of epithelioid-like cells with rhabdoid features and the absence of a granuloma-like pattern. In this paper we present a case of proximal-type epithelioid sarcoma with an aggressive clinical course, including distant metastasis and death nine months after diagnosis.O sarcoma epitelióide, primeiramente descrito por Enzinger, em 1970, é uma neoplasia de partes moles que ocorre principalmente nas extremidades distais de adolescentes e adultos jovens. Em 1997, Guillou e cols. descreveram um tipo diferente de sarcoma epitelióide, que afetava frequentemente a região pélvica, períneo e áreas genitais de pacientes de média idade, com exame histológico caracterizado pela proliferação de células com aspecto epitelióide. Neste trabalho, descreve-se caso de paciente que apresentava há três meses duas lesões na região glútea, cujo exame histológico confirmou diagnóstico de sarcoma epitelioide do tipo proximal, já com presença de metástases pulmonares e cerebrais e que foi a óbito nove meses após o diagnóstico.

  19. Carcinoma diferenciado da tireóide: a validade da complementação da tireoidectomia

    Directory of Open Access Journals (Sweden)

    José Luís Braga de Aquino

    Full Text Available OBJETIVO: Analisar a invasão tumoral do lobo contralateral da glândula tireóide no carcinoma diferenciado, correlacionando o risco/benefício com as complicações decorrentes de uma segunda intervenção. MÉTODO: De outubro/93 a dezembro/96 foram operados 20 pacientes com carcinomas diferenciados da glândula tireóide. Os parâmetros analisados foram sexo, idade, tipo de operação, tipo de complicações, histopatológico da peça cirúrgica e invasão do lobo contralateral. Eram dois pacientes do sexo masculino (10% e 18 do feminino (90%; as idades variaram de 17 a 89 anos; o tipo histológico mais freqüente foi o carcinoma papilífero (13 casos, seguido do folicular (seis casos e carcinoma de células de Hürthle (um caso. Como primeiro procedimento cirúrgico houve 11 lobectomias + istmectomias, quatro lobectomias subtotais e uma istmectomia. Cinco pacientes não realizaram a totalização (um por fibrose, três por perda de seguimento e um por ser microcarcinoma. RESULTADOS: Na análise do lobo contralateral realizada em 15 pacientes, 11 resultaram negativas e outras quatro positivas (26,6%. As complicações apresentadas foram rouquidão (dois casos revertidos com tratamento fonoterápico, hipoparatireoidismo (dois casos, um transitório e um permanente. CONCLUSÃO: A totalização da tireoidectomia é um procedimento importante no tratamento do tumor maligno da tireóide pela alta porcentagem de metástase contralateral (26,6%. Além disso, é um procedimento com mortalidade nula e pequena incidência de complicações.

  20. Expressão antigênica em carcinomas do plexo coróide humano: relato de dois casos

    Directory of Open Access Journals (Sweden)

    M. C. Almeida

    1990-09-01

    Full Text Available Neoplasias provenientes do epitélio de revestimento do plexo coróide são inco-muns, tendo sido descritos 6 padrões morfológicos. O padrão anaplásico, também denominado carcinoma do plexo coróide, é o de menor freqüência e pode dar metastases fora do SNC. A distinção histológica desses tumores, particularmente da variedade anaplásica, com outras neoplasias primárias e metastáticas no SNC pode ser difícil. O uso de técnicas imunocitoquimicas em parafina tem-se mostrado útil no esclarecimento das linhagens tumorais. Os papilomas do plexo coróide têm, no entanto, sido objeto de controvérsia, por sua complexa expressão antigênica. Usando a técnica de imunoperoxidase (sistema avidina-biotina-peroxidase pesquisaram-se, em dois casos da variedade anaplásica, os seguintes marcadores: proteína glial fibrilar ácida (GFAP com anticorpo monoclonal e policlonal; ceratinas de 40-50kDa, ceratinas de 60-70kDa (callus ceratina, enolase neuronal específica (NSE e proteína S-100, com anticorpos monoclonais. Os dois tumores mostraram positividade para NSE, proteína S-100 e ceratina de 40-50kDa; uma das duas neoplasias mostrou diferenciação glial, revelando positividade para GFAP tanto com anticorpo monoclonal quanto policlonal.

  1. Larvas de Geometridae (Lepidoptera) e seus parasitóides, associadas a Erythroxylum microphyllum St.- Hilaire (Erythroxylaceae)

    OpenAIRE

    Marconato,Gláucia; Dias,Manoel Martins; Penteado-Dias,Angélica Maria

    2008-01-01

    O trabalho foi realizado em área de cerrado, em São Carlos, São Paulo, Brasil. Foram realizadas amostragens quinzenais de junho/1999 a junho/2000, por meio de guarda-chuva-entomológico. Foram registradas 22 espécies de Geometridae pertencentes a 14 gêneros; quanto aos parasitóides, 11 gêneros de Hymenoptera e dois de Diptera, Tachinidae. A ocorrência de Cyclomia mopsaria (Geometridae) foi de 83%. Outros Geometridae registrados foram: Glena unipennaria, G. bipennaria, G. demissaria, G. brachia...

  2. O sistema endocanabinóide: novo paradigma no tratamento da síndrome metabólica

    OpenAIRE

    Godoy-Matos, Amélio F. de; Guedes, Erika Paniago; Souza, Luciana Lopes de; Valério, Cynthia Melissa

    2006-01-01

    O balanço energético é um dos mais importantes mecanismos de homeostase e de sobrevivência das espécies. O sistema endocanabinóide é um novo e importante componente entre estes mecanismos. Os seus receptores e agonistas endógenos se expressam no sistema nervoso central (SNC) e perifericamente, em vários sítios, estabelecendo uma rede de comunicação periferiaSNC. Um aspecto marcante é a sua expressão no tecido adiposo, onde regula a lipogênese e aumenta a expressão de genes influentes no metab...

  3. Armadilhas da Nova Era: natureza e maternidade no ideário da humanização do parto

    Directory of Open Access Journals (Sweden)

    Tornquist Carmen Susana

    2002-01-01

    Full Text Available RESUMO Este artigo trata de caracterizar brevemente o Movimento pela Humanização do Parto e do Nascimento no Brasil, o qual tem buscado promover modificações na assistência ao parto e ao nascimento, sobretudo no âmbito da saúde coletiva. Busca também refletir sobre as noções de Natureza e Maternidade, centrais no ideário do Movimento, bem como os limites de uma noção de empoderamento das mulheres nesse contexto.

  4. 19 CFR 148.55 - Exemption for articles bearing American trademark.

    Science.gov (United States)

    2010-04-01

    ... registered with the U.S. Patent and Trademark Office and recorded with Customs. The exemption may be applied... 19 Customs Duties 2 2010-04-01 2010-04-01 false Exemption for articles bearing American trademark... § 148.55 Exemption for articles bearing American trademark. (a) Application of exemption. An exemption...

  5. Aplicação de formulação do fungo predador de nematóides Monacrosporium thaumasium (Drechsler, 1937 no controle de nematóides de bovinos

    Directory of Open Access Journals (Sweden)

    Alves P.H.

    2003-01-01

    Full Text Available A viabilidade de uma formulação do fungo Monacrosporium thaumasium (Drechsler, 1937 foi avaliada no controle biológico de nematóides parasitos gastrintestinais de bovinos. Dois grupos de sete bezerras cada, mestiças Holandês ´ Zebu, de quatro a seis meses de idade, foram colocados em pastagens de Cynodon dactilon. No grupo A, cada animal recebeu 20g de pellets (formulação granulada de M. thaumasium via oral, duas vezes por semana, durante quatro meses, com início na estação chuvosa (outubro, 2001. No grupo B (controle, as bezerras não receberam nenhum tratamento. As contagens de ovos por grama de fezes (OPG e das larvas infectantes encontradas na pastagem do grupo B foram significativamente maiores (P<0,05 do que as do grupo A e a diferença entre o OPG dos animais dos grupos A e B, no final do experimento, foi de 88,8%. O gênero Cooperia foi o mais prevalente em ambas as pastagens. Conclui-se que a aplicação de pellets de M. thaumasium na dosagem e periodicidade de aplicação usadas foi eficiente no controle de nematóides parasitos gastrintestinais de bovinos.

  6. Esteróides anabolizantes no esporte Anabolic steroids in sports

    Directory of Open Access Journals (Sweden)

    Paulo Rodrigo Pedroso da Silva

    2002-12-01

    Full Text Available Os hormônios esteróides anabólicos androgênicos (EAA compreendem a testosterona e seus derivados. Eles são produzidos nos testículos e no córtex adrenal, e promovem as características sexuais secundárias associadas à masculinidade. Na medicina, os EAA são utilizados geralmente no tratamento de sarcopenias, do hipogonadismo, do câncer de mama e da osteoporose. Nos esportes, são utilizados para o aumento da força física e da massa muscular; entretanto, os efeitos sobre o desempenho atlético permanecem, ainda, controversos. Os EAA podem causar diversos efeitos colaterais, como psicopatologias, câncer de próstata, doença coronariana e esterilidade. Estudos epidemiológicos apontam a problemática acerca do uso de EAA, nos esportes; todavia, no Brasil não existem publicações substanciais sobre esse tema. Esta revisão analisa esse assunto, procurando despertar a curiosidade e o interesse dos leitores para a produção científica de novos trabalhos relacionados ao tema.Anabolic androgenic steroids (AAS are hormones that include or are derivatives of testosterone. They are produced in the testicles and in the adrenal cortex. AAS promote development of sexual characteristics associated with the male sex. They are applied as a general rule in the treatment of sarcopenia, hypogonadism, breast cancer, and osteoporosis. In relation to sports, they are used to increase strength and muscle mass. Their effects on athletics performance are still controversial. AAS can cause several side-effects, such as mental disease, prostate cancer, coronary disease, and sterility. There are no epidemiologic studies regarding the use of AAS in Brazil . This review intends to deal with this matter widely and aims at stimulating curiosity and interest in order to provide new publications about this issue.

  7. Notes on a homogeneous reactor project; Idees sur un projet de reacteur homogene

    Energy Technology Data Exchange (ETDEWEB)

    Benveniste, J; Bernot, J; Eidelman, D; Grenon, M; Portes, L; Raspaud, G; Tachon, J; Vendryes, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires; Berthod, L; Cohen de Lara, G; Delachanal, M; Fontanet, P; Halbronn, G [Societe Grenobloise d' Etudes et d' Applications Hydrauliques, 38 (France)

    1958-07-01

    An attempt has been made to develop certain ideas concerning homogeneous reactors. The project under consideration is based on the simultaneous use of a suspension of uranium dispersed in heavy or light water and of boiling in the reactor for heat extraction. However, the studies of suspensions and of boiling are relatively independent and can also be developed for reactors of different types using one or the other. Our aim is a minimum investment in fissile material; for this we propose to extract the steam directly from the core and to make use of a cyclone to accelerate this extraction; a cyclone-type circulation creating a field of increasing tangential velocities of the fluid towards the axis causes the droplets of vapour to accelerate towards the axial vortex in which they are collected; the steam output is then evacuated to the external heat utilisation system, for example an exchanger of the condenser-boiler type. The input speed of water into the reactor being one of the important parameters in the running of the pile, a spiral supply input chamber is used, allowing this speed to be regulated in amount and direction. (author)Fren. [French] Nous nous sommes attaches a developper certaines idees relatives aux piles homogenes. Le projet que nous etudions est base sur l'emploi simultane d'une suspension contenant de l'uranium disperse dans l'eau legere ou lourde et de l'ebullition dans le reacteur pour l'extraction de chaleur. Neanmoins, les etudes de suspensions et d'ebullition sont relativement independantes et peuvent egalement etre developpees pour des reacteurs de type different utilisant l'une ou l'autre. Le but que nous cherchons a atteindre est un investissement minimum en matiere fissile; pour cela, nous proposons d'extraire directement la vapeur dans le coeur et de recourir a un dispositif cyclone pour accelerer cette extraction; une circulation type cyclone creant un champ de vitesses tangentielles du fluide croissantes veraxe a pour effet d

  8. International survey of seat belt use exemptions.

    Science.gov (United States)

    Weiss, H; Sirin, H; Levine, J A; Sauber, E

    2006-08-01

    Substantial evidence of seatbelt efficacy has been shown by several studies, and it is widely recommended that motor vehicle occupants use properly fitted seat belts. However, some (but a heretofore unknown number of) countries with national seat belt laws permit various exemptions which may lower use rates. The aim of this study was to survey the variety of exemptions to national seat belt laws. This investigation relied on identifying respondents from national traffic safety agencies, other governmental and non-governmental organizations, Internet searches, personal contacts, and other sources. Questionnaires were deployed through a web based survey supplemented by email and postal versions. Responses were received from 30 countries of which 28 (93.7%) had a national seat belt law. About two thirds (63.7%) of the 28 national laws applied to both front and back seat passengers. The leading exemption types included vehicles made before a certain year (n = 13), antique vehicles (n = 12), military vehicles (n = 11), buses (n = 9), and emergency vehicles (n = 8). Most responding countries reported one or more specific categories of individuals as exempt including those with medical exemptions (n = 20), taxi drivers (n = 11), police (n = 9), emergency medical personnel (n = 8), physically disabled people (n = 6), and pregnant women (n = 6). Out of 26 responses to the question regarding current level of enforcement, 42.3% felt enforcement was "very good or good" and 57.7% characterized it as "fair or poor". This study represents one of the largest international traffic law surveys reported. Most national seatbelt laws offer perilous exemptions to a broad array of vehicle types and road user groups. These findings, coupled with concern over the level of enforcement in the majority of countries surveyed, suggest that international road safety efforts have a long way to go to improve coverage and enforcement of national seat belt laws.

  9. Genomic population structure of freshwater-resident and anadromous ide (Leuciscus idus) in north-western Europe

    DEFF Research Database (Denmark)

    Skovrind, Mikkel; Olsen, Morten Tange; Garrett Vieira, Filipe Jorge

    2016-01-01

    to become increasingly affected by changes in salinity is the ide (Leuciscus idus). The ide is a stenohaline freshwater fish that primarily inhabits rivers, with frequent anadromous behavior when sea salinity does not exceed 15%. Unlike most other anadromous Baltic Sea fish species, the ide has yet......Climate change experts largely agree that future climate change and associated rises in oceanic water levels over the upcoming decades, will affect marine salinity levels. The subsequent effects on fish communities in estuarine ecosystems however, are less clear. One species that is likely...... to be subjected to large-scale stocking programs, and thus provides an excellent opportunity for studying the natural population structure across the current salinity gradient in the Danish Belts. To explore this, we used Genotyping-by-Sequencing to determine genomic population structure of both freshwater...

  10. Carotenóides de bactérias halófilas : produção, caracterização e atividade antioxidante

    OpenAIRE

    Viviane Santos Miranda

    2010-01-01

    Resumo: O interesse pelos carotenóides tem aumentado consideravelmente nos últimos anos pela evidência dos seus já conhecidos benefícios à saúde humana, devido às suas propriedades antioxidantes, anticarcinogênicas e imunomodulatórias. As principais fontes industriais de carotenóides são a síntese química e a extração a partir de plantas e microalgas, porém são poucos os carotenóides cuja produção seja economicamente viável. Considerando que os microrganismos extremófilos são importantes font...

  11. Impacto de inseticidas sobre parasitóides da traça-das-crucíferas em repolho, no Distrito Federal

    Directory of Open Access Journals (Sweden)

    Castelo Branco Marina

    2001-01-01

    Full Text Available Este trabalho teve como objetivo identificar os parasitóides da Plutella xylostella(L. presentes em áreas de cultivo do Distrito Federal, tratadas ou não com inseticidas, onde larvas do inseto foram coletadas. Foram identificados quatro parasitóides: Apantelessp. (Braconidae, Oomyzus sokolowiskii (Kurdjumov (Eulophidae, Diadegmasp. (Ichneumonidae e Actiasp. (Tachinidae. Onível de parasitismo nas áreas não tratadas com inseticidas variou de 5% a 94%, enquanto em áreas tratadas variou de 11% a 87%. A maior parte das larvas de traça-das-crucíferas foram encontradas nas cabeças de repolho ou na parte inferior das folhas da saia das plantas. Esta distribuição de larvas sobre as plantas deve permitir que estas escapem do contato com o inseticida, e, conseqüentemente, os parasitóides podem sobreviver nas plantas tratadas.

  12. Predicting Exemptions and Hardship in CISG Context

    DEFF Research Database (Denmark)

    Lookofsky, Joseph

    2016-01-01

    In this contribution to the Liber Amicorum Festschrift in honor of Peter Møgelvang-Hansen, the author revisits and casts new light on force majeure and liability exemptions under the 1980 UN Convention on Contracts for the International Sale of Goods, including recent developments in CISG Article...... 79 theory and practice, as well as the advent of a highly controversial conundrum: how to handle ‘hardship’ in the liability-exemptions context? By way of introduction to this particular CISG topic area, the author sketches the larger Sales Convention picture and its relationship to domestic law...

  13. Stakeholder engagement for comparative effectiveness research in cancer care: experience of the DEcIDE Cancer Consortium.

    Science.gov (United States)

    Greenberg, Caprice C; Wind, Jennifer K; Chang, George J; Chen, Ronald C; Schrag, Deborah

    2013-03-01

    Stakeholder input is a critical component of comparative effectiveness research. To ensure that the research activities of the Developing Evidence to Inform Decisions about Effectiveness (DEcIDE) Network, supported by the Agency for Healthcare Research and Quality, translate into the greatest impact for everyday practice and policy-making in cancer, we were tasked with soliciting stakeholder input regarding priority areas in cancer-related comparative effectiveness research for the DEcIDE Cancer Consortium. Given the increasing emphasis on stakeholder engagement in research, many investigators are facing a similar task, yet there is limited literature to guide such efforts, particularly in cancer care. To help fill this gap, we present our approach to operationalizing stakeholder engagement and discuss it in the context of other recent developments in the area. We describe challenges encountered in convening stakeholders from multiple vantage points to prioritize topics and strategies used to mitigate these barriers. We offer several recommendations regarding how to best solicit stakeholder input to inform comparative effectiveness research in cancer care. These recommendations can inform other initiatives currently facing the challenges of engaging stakeholders in priority setting for cancer.

  14. Study of different 3-aminopropyl triethoxysilane (APTES) concentration on TiO2 particles based IDE for cervical cancer detection

    Science.gov (United States)

    Raqeema, S.; Hashim, U.; Azizah, N.; Nadzirah, Sh.; Arshad, M. K. Md; Ruslinda, A. R.; Gopinath, Subash C. B.

    2017-03-01

    HPV that also called Human Papillomaviruses is the major cause of the cervical cancer. HPV 16 and HPV 18 are the two types of HPV are the most HPV-associated cancers and responsible as a high-risk HPV. Cervical cancer taken about 70 percent of all cases due HPV infections. Cervical malignancy for the most part development on a lady's cervix and its was developed slowly as cancer disease. TiO2 particles give better performance and low cost of the biosensor. The used of 3-aminopropyl triethoxysilane (APTES) will be more efficient for DNA nanochip. APTES used as absorption reaction to immobilize organic biomolecules on the inorganic surface. Besides, APTES give better functionalization of the adsorption mechanism on IDE. The surface functionalized for immobilizing the DNA, which is the combination of the DNA probe and the HPV target produce high sensitivity andfast detection of the IDE. The Current-Voltage (IV) characteristic proved the sensitivity of the DNA nanochip increase as the concentration varied from 0% concentration to 24% of APTES concentration.

  15. A inércia estrutural da base produtiva brasileira: o IDE e a transferência internacional de tecnologia

    Directory of Open Access Journals (Sweden)

    TULIO CHIARINI

    2016-06-01

    Full Text Available RESUMO O que pode explicar o fato de ter havido uma entrada maciça de IDE no Brasil e ter-se mantido uma inercial estrutural na base produtiva nacional? Existe uma série de fatos macroeconômicos que podem ajudar a explicar essa inércia, como a baixa taxa de investimento e a falta de ordenação dos preços-chave da economia (como taxas de juros e taxa de câmbio, mas a proposição aqui feita é que existe um problema microeconômico estrutural relevante: falta de aptidão tecnológica das empresas industriais brasileiras. Para analisar tal proposição parte-se da separação entre os tipos de IDE (greenfield, fusão e aquisição e 'em carteira' e os tipos de canais de transferência de tecnologia (horizontal e vertical. A partir de elementos empíricos e históricos constrói-se o argumento de que a falta de aptidão tecnológica é elemento-chave no entendimento da perda de dinamismo da indústria nacional.

  16. REAÇÃO DA PINHA (Annona squamosa L. A TRÊS ESPÉCIES DE FITONEMATÓIDES

    Directory of Open Access Journals (Sweden)

    A.R. Monteiro

    1996-05-01

    Full Text Available Em ensaio conduzido em vasos, a céu aberto, estudou-se a reação de Annona squamosa em relação a três nematóides fitoparasitos. As plantas foram inoculadas com 10.000 exemplares de Radopholus similis, Rotylenchulus reniformis ou Meloidogyne exigua por recipiente. Avaliaram-se, após três meses da inoculação, a altura das plantas, o peso fresco do sistema radicular e o número de nematóides nas raízes e no solo. O estudo revelou que a Annona squamosa comportou-se como resistente a Rotylenchulus reniformis e a Meloidogyne exigua, e intolerante a Radopholus similis.The host reaction of custard apple (Annona squamosa to three species of nematodes was studied. The plants were inoculated with 10,000 specimens per plant of Radopholus similis, Rotylenchulus reniformis or Meloidogyne exigua. Nematode population and plant growth parameters were evaluated three months later. The results showed that custard apple was resistent to Rotylenchulus reniformis and Meloidogyne exigua but intolerant to Radopholus similis.

  17. Expressão do colágeno I em carcinomas epidermóides da cavidade oral

    Directory of Open Access Journals (Sweden)

    Martins Gabriela Botelho

    2003-01-01

    Full Text Available A matriz extracelular no carcinoma epidermóide da cavidade oral sofre modificações qualitativas e quantitativas durante a sua progressão. Estas alterações parecem possibilitar os processos de invasão e metástase que caracterizam as neoplasias malignas e são mais evidentes na interface tumor-hospedeiro. No nosso estudo, 23 biópsias incisionais de carcinomas epidermóides de diversas localizações da cavidade oral foram classificadas segundo o sistema de graduação histológica preconizado por Anneroth et al.¹ (1987. Foram utilizadas as colorações pela H. E. e a do tipo picrosirius, específica para colágeno. A expressão imuno-histoquímica do colágeno tipo I foi analisada em lesões com diferentes escores histológicos de malignidade. Pôde-se concluir que o colágeno apresenta diferentes padrões morfológicos, histoquímicos e imuno-histoquímicos em lesões com altos e baixos escores de malignidade.

  18. Expressão dos marcadores tumorais CD-34 e CASPASE-3 no carcinoma epidermóide de esôfago

    OpenAIRE

    Ferreira,Valério Alves; Czeczko,Nicolau Gregori; Ribas-Filho,Jurandir Marcondes; Malafaia,Osvaldo; Ribas,Carmen Austrália Paredes Marcondes; Gomes,Claudia Stein; Cunha,Regina Maria da; Cuenca,Ronaldo M.

    2009-01-01

    OBJETIVO: Analisar citofotometricamente a expressão do marcador de densidade microvascular CD-34 e de apoptose caspase-3 no carcinoma epidermóide de esôfago, e correlacionar os marcadores entre si. MÉTODOS: Análise imunoistoquímica de 29 peças cirúrgicas de carcinomas epidermóides de esôfago, baseada nos índices de marcagem dos anticorpos CD-34 e caspase-3, utilizando-se sistema de citofotometria computadorizada. Comparou-se a expressão quantitativa destes marcadores, a relação entre eles, a ...

  19. Em busca de determinantes estruturais no reconhecimento e ligação de amilóide: β-2 microglobulina como caso de estudo

    OpenAIRE

    Fernandes, Pedro Miguel Pinto

    2016-01-01

    O desenvolvimento de novas e melhores sondas moleculares para o diagnóstico precoce de doenças amilóides como Alzheimer, Parkinson e diabetes tipo II é essencial para o estabelecimento de estratégias terapêuticas adequadas. A β-2 microglobulina (β2m) é uma proteína associada ao complexo Major de Histocompatibilidade de classe I. Nos doentes que realizam tratamentos prolongados de hemodiálise, a β2m pode agregar e formar fibras amilóides que se depositam nos rins e nas articulaç...

  20. Presença de auto-anticorpos não-tireóide-específicos no soro de pacientes com hipotireoidismo auto-imune

    OpenAIRE

    Soares Débora Vieira; Vanderborght Bart O. M.; Vaisman Mário

    2003-01-01

    Auto-anticorpos contra componentes não-específicos da tireóide foram encontrados no soro de pacientes com doença auto-imune da tireóide. Neste estudo avaliamos a presença de auto-anticorpos antinucleares (ANA), antimúsculo liso (anti-ML) e antimitocôndria (anti-Mc) no soro de pacientes com hipotireoidismo auto-imune (HA), comparando-os a controles saudáveis. Estudamos 70 pacientes com hipotireoidismo auto-imune (tireoidite de Hashimoto ou tireoidite atrófica ) e 70 controles saudáveis (sem di...

  1. Public service quality improvements: a case for exemption from IRB review of public administration research.

    Science.gov (United States)

    Jordan, Sara R

    2014-01-01

    Should the exemption from Institutional Review Board (IRB) evaluations currently in place for quality improvements research be extended to public administration research that addresses questions of improving the quality of public service delivery? As a means to both reduce the level of disdain held by a group of social science researchers for IRBs and to reduce the cost of review for minimal risk studies, I argue here that much of the current public administration research should also be exempted from normal processes of review by IRBs on the basis of their similarity to Quality Improvements (QI) research, a category of studies already granted exemption. This argument dovetails provisions currently in place for studies of public service and public benefit, but reframes these exemptions in the language of "quality improvements," which may be a more comfortable language for IRBs concerned to demonstrate compliance for review of all fields. To expedite this argument into the practices of IRBs, I included a checklist that researchers could use to self-identify their studies as QI, not research as such.

  2. Polymer Exemption for New Chemicals under the Toxic Substances Control Act (TSCA)

    Science.gov (United States)

    EPA has established an exemption for certain polymers to encourage manufacturers to make safer polymers. To learn more about this exemption, eligibility, and it's requirements, read this overview of the exemption.

  3. 12 CFR 26.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false General exemption. 26.6 Section 26.6 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY MANAGEMENT OFFICIAL INTERLOCKS § 26.6... minority group, or women; (3) Is a depository institution that has been chartered for less than two years...

  4. 12 CFR 711.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false General exemption. 711.6 Section 711.6 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS MANAGEMENT... are members of a minority group or women; (3) Is a depository institution that has been chartered for...

  5. 12 CFR 348.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false General exemption. 348.6 Section 348.6 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY... minority group, or women; (3) Is a depository institution that has been chartered for less than two years...

  6. 12 CFR 563f.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false General exemption. 563f.6 Section 563f.6 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY MANAGEMENT OFFICIAL INTERLOCKS... controlled or managed by persons who are members of a minority group, or women; (3) Is a depository...

  7. 12 CFR 212.6 - General exemption.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false General exemption. 212.6 Section 212.6 Banks and Banking FEDERAL RESERVE SYSTEM BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM MANAGEMENT... women; (3) Is a depository institution that has been chartered for less than two years; or (4) Is deemed...

  8. 32 CFR 312.12 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... classified in the interest of national defense or foreign policy. This specific exemption rule, claimed by... subsection (c)(3) because the release of accounting of disclosure would inform a subject that he or she is...) because the nature of the criminal and/or civil investigative function creates unique problems in...

  9. 49 CFR 605.11 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ...) That private school bus operators in the urban area are unable to provide adequate transportation, at a... 49 Transportation 7 2010-10-01 2010-10-01 false Exemptions. 605.11 Section 605.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION, DEPARTMENT OF...

  10. 49 CFR 1007.12 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ... Government under an express promise that the identity of the source would be held in confidence, or, prior to the effective date of this section, under an implied promise that the identity of the source would be... suitability, eligibility, or qualifications for employment with or contracts with the Board are exempt from...

  11. 31 CFR 595.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM SANCTIONS REGULATIONS Prohibitions § 595.206 Exempt transactions. (a) Personal communications. The prohibitions contained in this part do not apply to any postal, telegraphic, telephonic, or other personal communication, which does not involve the...

  12. 32 CFR 291.8 - Exemptions.

    Science.gov (United States)

    2010-07-01

    .... This exemption has two profiles, high b2 and low b2. (i) Records qualifying under high b2 are those... under the low b2 profile are those that are trivial and housekeeping in nature for which there is no... provided in confidence by private employers in connection with locality wage surveys that are used to fix...

  13. 12 CFR 760.4 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Exemptions. 760.4 Section 760.4 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS LOANS IN AREAS HAVING... apply with respect to: (a) Any State-owned property covered under a policy of self-insurance...

  14. 44 CFR 6.86 - General exemptions.

    Science.gov (United States)

    2010-10-01

    ... Management Agency, to exercise the right to promulgate rules to exempt such systems in accordance with the... suspects or as subjects of a criminal investigation; this would compromise the ability of the Federal... criminal investigations and to detect or identify violators of laws administered by the Federal Emergency...

  15. 8 CFR 313.3 - Statutory exemptions.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Statutory exemptions. 313.3 Section 313.3 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY NATIONALITY REGULATIONS MEMBERSHIP IN THE... education will qualify as an essential of living only if the applicant can establish the existence of...

  16. 29 CFR 570.126 - Parental exemption.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Parental exemption. 570.126 Section 570.126 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS CHILD LABOR REGULATIONS, ORDERS AND STATEMENTS OF INTERPRETATION General Statements of Interpretation of the Child Labor...

  17. 40 CFR 2.105 - Exemption categories.

    Science.gov (United States)

    2010-07-01

    ... the mandatory disclosure requirements of 5 U.S.C. 552(a): (1)(i) Specifically authorized under... enforcement investigations or prosecutions if such disclosure could reasonably be expected to risk... for Disclosure of Records Under the Freedom of Information Act § 2.105 Exemption categories. (a) The...

  18. 19 CFR 103.12 - Exemptions.

    Science.gov (United States)

    2010-04-01

    ... AVAILABILITY OF INFORMATION Production of Documents/Disclosure of Information Under the FOIA § 103.12 Exemptions. Pursuant to 5 U.S.C. 552(b), the disclosure requirements of 5 U.S.C. 552(a) are not applicable to... if such disclosure could reasonably be expected to risk circumvention of the law; or (6) Could...

  19. 49 CFR 580.17 - Exemptions.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF TRANSPORTATION (CONTINUED) ODOMETER DISCLOSURE REQUIREMENTS § 580.17 Exemptions... Rating, as defined in § 571.3 of this title, of more than 16,000 pounds; (2) A vehicle that is not self... (a) of this section need not notify the lessee of any of these vehicles of the disclosure...

  20. Allegheny County Clean Indoor Air Act Exemptions

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — List and location of all the businesses and social clubs who have received an exemption from the Pennsylvania Clean Indoor Air Act. “The Clean Indoor Air Act, Act...

  1. 10 CFR 170.11 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... unreviewed safety issue; (ii) In response to an NRC request from the Associate Office Director level or above... NRC's review and approval of these documents. This exemption does not apply to a topical report... of the type of document that does not meet the fee waiver criteria is a topical report submitted for...

  2. 31 CFR 588.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 588.206 Section 588.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  3. 31 CFR 560.210 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 560.210 Section 560.210 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... services to market, produce or co-produce, create or assist in the creation of information and...

  4. 31 CFR 545.208 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 545.208 Section 545.208 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  5. 31 CFR 542.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 542.206 Section 542.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  6. 31 CFR 587.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 587.206 Section 587.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF...-produce, create, or assist in the creation of information or informational materials; and, with respect to...

  7. 31 CFR 539.204 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 539.204 Section 539.204 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... of services to market, produce or co-produce, create, or assist in the creation of information or...

  8. 31 CFR 586.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 586.206 Section 586.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... or assist in the creation of information and informational materials, and payment of royalties to...

  9. 31 CFR 536.205 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 536.205 Section 536.205 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... creation of information and informational materials, and payment of royalties to a specially designated...

  10. 31 CFR 537.210 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 537.210 Section 537.210 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  11. 31 CFR 538.212 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 538.212 Section 538.212 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... services to market, produce or co-produce, create or assist in the creation of information and...

  12. 31 CFR 548.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 548.206 Section 548.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  13. 31 CFR 544.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 544.206 Section 544.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF...-produce, create, or assist in the creation of information or informational materials; and, with respect to...

  14. 31 CFR 541.206 - Exempt transactions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Exempt transactions. 541.206 Section 541.206 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... assist in the creation of information or informational materials; and, with respect to information or...

  15. 12 CFR 791.12 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... criteria for withholding or refers to particular types of matters to be withheld; (4) Disclose trade... which would be likely to (i)(A) lead to significant speculation in currencies, securities, or... balance the public interest in observing the deliberations of an exemptible matter and the agency need for...

  16. 7 CFR 1218.53 - Exemption procedures.

    Science.gov (United States)

    2010-01-01

    ... exemption is claimed. (c) A producer who operates under an approved National Organic Program (NOP) (7 CFR part 205) system plan; produces only products that are eligible to be labeled as 100 percent organic... organic farm or organic handling operation certificate provided by a USDA-accredited certifying agent as...

  17. 7 CFR 1209.252 - Exemption procedures.

    Science.gov (United States)

    2010-01-01

    ... in section 2103 of the Organic Foods Production Act of 1990 (7 U.S.C. 6502), a signed certification.... (2) To apply for an exemption for organic mushrooms: (i) An eligible mushroom producer shall submit a...) The request shall include the following: The producer's name and address, a copy of the organic farm...

  18. 40 CFR 82.65 - Temporary exemptions.

    Science.gov (United States)

    2010-07-01

    ...) PROTECTION OF STRATOSPHERIC OZONE Ban on Nonessential Products Containing Class I Substances and Ban on Nonessential Products Containing or Manufactured With Class II Substances § 82.65 Temporary exemptions. (a) Any... January 1, 1996. (e) Any person selling or distributing, or offering to sell or distribute, any product...

  19. 15 CFR 4.34 - Specific exemptions.

    Science.gov (United States)

    2010-01-01

    ...—COMMERCE/DEPT-14; and (ii) The foregoing are exempted from 5 U.S.C. 552a (c)(3), (d), (e)(1), (e)(4)(G), (H... Censuses—COMMERCE/ CENSUS-5; (E) Population Census Personal Service Records for 1900 and All Subsequent... Midshipman Personnel Files—COMMERCE/MA-18; (D) USMMA Non-Appropriated fund Employees—COMMERCE/MA-19; (E...

  20. 40 CFR 147.2908 - Aquifer exemptions.

    Science.gov (United States)

    2010-07-01

    ... portion that meets the definition of a USDW may be exempted by EPA from USDW status if the following... will not in the future serve as a source of drinking water because: (i) It is hydrocarbon producing, or... to contain hydrocarbons that are expected to be commercially producible (based on historical...

  1. 12 CFR 226.3 - Exempt transactions.

    Science.gov (United States)

    2010-01-01

    ... personal property used or expected to be used as the principal dwelling of the consumer; or (2) A private... convenience of the user, the revised text is set forth as follows: § 226.3 Exempt transactions. This... the consumer, in which the amount financed exceeds $25,000 or in which there is an express written...

  2. 32 CFR 292.6 - FOIA exemptions.

    Science.gov (United States)

    2010-07-01

    ... INFORMATION ACT PROGRAM DEFENSE INTELLIGENCE AGENCY (DIA) FREEDOM OF INFORMATION ACT § 292.6 FOIA exemptions... footnote 1 to § 292.3(a)(3). 5 Forward requests to: Defense Intelligence Agency, ATTN: DSP-1A (FOIA... containing trade secrets or commercial or financial information that the DIA receives from a person or...

  3. 29 CFR 553.216 - Other exemptions.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Other exemptions. 553.216 Section 553.216 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS APPLICATION OF THE FAIR LABOR STANDARDS ACT TO EMPLOYEES OF STATE AND LOCAL GOVERNMENTS Fire Protection and Law...

  4. 38 CFR 49.29 - Conditional exemptions.

    Science.gov (United States)

    2010-07-01

    ...) UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 49...-administered, non-entitlement grant programs from certain OMB grants management requirements. The exemptions...

  5. 41 CFR 60-1.5 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... society, or if the curriculum of such school, college, university, or other educational institution or... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Exemptions. 60-1.5 Section 60-1.5 Public Contracts and Property Management Other Provisions Relating to Public Contracts...

  6. 48 CFR 9904.402-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.402-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.402-62 Exemption. None for this Standard. ...

  7. 48 CFR 9904.407-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.407-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.407-62 Exemption. None for this Standard. ...

  8. 48 CFR 9904.404-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.404-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.404-62 Exemption. None for this Standard. ...

  9. 48 CFR 9904.406-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.406-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.406-62 Exemption. None for this Standard. ...

  10. 48 CFR 9904.401-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.401-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-62 Exemption. None for this Standard. ...

  11. 48 CFR 9904.409-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.409-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.409-62 Exemption. This Standard shall not apply where compensation...

  12. 48 CFR 9904.405-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.405-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.405-62 Exemption. None for this Standard. ...

  13. 48 CFR 9904.408-62 - Exemption.

    Science.gov (United States)

    2010-10-01

    ... Section 9904.408-62 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.408-62 Exemption. This Standard shall not apply to contracts and...

  14. 40 CFR 372.38 - Exemptions.

    Science.gov (United States)

    2010-07-01

    ... the facility such as in a facility operated cafeteria, store, or infirmary. (4) Use of products... facility is operated. This exemption applies to owners of facilities such as industrial parks, all or part... such as industrial parks. If two or more persons, who do not have any common corporate or business...

  15. 29 CFR 780.329 - Exempt work.

    Science.gov (United States)

    2010-07-01

    ... That Is Exempted From the Minimum Wage and Overtime Pay Requirements Under Section 13(a)(6) Statutory... of agricultural labor performed by individuals not so engaged, he is required to pay the minimum wage... Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR STATEMENTS OF GENERAL POLICY OR...

  16. 21 CFR 1002.50 - Special exemptions.

    Science.gov (United States)

    2010-04-01

    ... and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... exemptions. (a) Manufacturers of electronic products may submit to the Director a request, together with... following criteria: (1) The products cannot emit electronic product radiation in sufficient intensity or of...

  17. 29 CFR 1602.36 - Schools exemption.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Schools exemption. 1602.36 Section 1602.36 Labor... REQUIREMENTS UNDER TITLE VII, THE ADA AND GINA State and Local Government Information Report § 1602.36 Schools... to State or local educational institutions or to school districts or school systems or any other...

  18. 9 CFR 130.49 - Exemptions.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Exemptions. 130.49 Section 130.49 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE USER... services, including, but not limited to, tests and diagnostic reagents specified in §§ 130.14 through 130...

  19. 40 CFR 92.905 - Testing exemption.

    Science.gov (United States)

    2010-07-01

    ....905 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Exclusion and Exemption Provisions § 92... fundamentally new emission control technology related either to an alternative fuel or an aftertreatment device...

  20. Complications of Lumbar Artificial Disc Replacement Compared to Fusion: Results From the Prospective, Randomized, Multicenter US Food and Drug Administration Investigational Device Exemption Study of the Charité Artificial Disc

    Science.gov (United States)

    Majd, Mohammed E.; Isaza, Jorge E.; Blumenthal, Scott L.; McAfee, Paul C.; Guyer, Richard D.; Hochschuler, Stephen H.; Geisler, Fred H.; Garcia, Rolando; Regan, John J.

    2007-01-01

    Background Previous reports of lumbar total disc replacement (TDR) have described significant complications. The US Food and Drug Administration (FDA) investigational device exemption (IDE) study of the Charité artificial disc represents the first level I data comparison of TDR to fusion. Methods In the prospective, randomized, multicenter IDE study, patients were randomized in a 2:1 ratio, with 205 patients in the Charité group and 99 patients in the control group (anterior lumbar interbody fusion [ALIF] with BAK cages). Inclusion criteria included confirmed single-level degenerative disc disease at L4-5 or L5-S1 and failure of nonoperative treatment for at least 6 months. Complications were reported throughout the study. Results The rate of approach-related complications was 9.8% in the investigational group and 10.1% in the control group. The rate of major neurological complications was similar between the 2 groups (investigational = 4.4%, control = 4.0%). There was a higher rate of superficial wound infection in the investigational group but no deep wound infections in either group. Pseudarthrosis occurred in 9.1% of control group patients. The rate of subsidence in the investigational group was 3.4%. The reoperation rate was 5.4% in the investigational group and 9.1% in the control group. Conclusions The incidence of perioperative and postoperative complications for lumbar TDR was similar to that of ALIF. Vigilance is necessary with respect to patient indications, training, and correct surgical technique to maintain TDR complications at the levels experienced in the IDE study. PMID:25802575

  1. Estudo cariométrico dos poliplóides de Coffea

    Directory of Open Access Journals (Sweden)

    Giorgio Schreiber

    1946-01-01

    Full Text Available Foi estudado o volume nuclear de uma série de plantas de café com 22-44-66-88 cromossômios: C. congensis, C. arabica var. monosperma, C. arabica var. typica e C. arabica var. bullata e pelo método estatístico cariométrico. Das curvas de frequência (que não são "normais", foi calculado o valor normal (modo para cada número de cromossômios. Com êstes valores modais e os respectivos números de cromossômios foi calculada a equação de regressão, o êrro de estimação e o coeficiente de correlação. A correlação é perfeita, sendo, porém, a espécie C. congensis discordante dos demais elementos da série por ter um valor volumétrico correspondente a 33 cromossômios apesar dos 22 encontrados nas metáfases somáticas. Êste resultado é apontado para ulteriores investigações citogenéticas sôbre esta espécie. O resultado geral destas pesquisas mostra a perfeita correlação entre o número de genomas haplóides e o volume nuclear ; deve ser considerado, porém, válido somente no confronto entre núcleos que se encontram na mesma fase do ciclo de crescimento interfásico.Caryometric researches on Coffea polyploids. General discussion of the problem and preliminary results. A series of polyploid plant of Coffea with 22, 44, 66, and 88 chromosomes (C. congensis, C. arabica var. monosperma, C. arabica var. typica, C. arabica var. bullata have been studied with caryometric statistical method. The chromosome numbers have been plotted again,st the modal value of the frequency curves of nuclear volume and the regression equation, standard error of estimation and correlation coefficent have been calculated. The correlation results perfect between the chromosome number and the nuclear volume for all the elements of the polyploid series of Coffea arabica. Coffea congensis, althought with 22 chromosomes, has a nuclear volume exactly correspondent to that of C. arabica with 33 chromosomes. This fact is appointed for further

  2. Molecular basis of Acute Myelogenous Leukemia As bases moleculares da leucemia mielóide aguda

    Directory of Open Access Journals (Sweden)

    Eduardo M. Rego

    2002-01-01

    Full Text Available Acute Myelogenous Leukemia (AML is frequently associated with recurring chromosomal translocations, which lead to the fusion of two genes encoding transcription factors. As the moieties of these fusion proteins retain part of the functional domains of the wild-type proteins, they may interfere directly or indirectly with the transcriptional regulation of the leukemic cell, conferring survival advantage. The majority of the transcription factors commonly involved in recurring chromosomal translocations may be grouped in one of the following families: core binding factor (CBF, retinoic acid receptor alpha (RARalpha, homeobox (HOX family, and mixed lineage leukemia (MLL. In vivo analysis of the molecular basis of leukemogenesis through the generation of transgenic mouse models revealed that a common theme is the recruitment of transcriptional co-activators and co-repressors by these fusion proteins. However, the expression of the fusion protein is not sufficient to induce full blown leukemia, as evidenced in part by the long latencies required for disease development in the transgenic models of leukemia, and therefore, second mutagenic events may contribute to AML pathogenesis.A leucemia mielóide aguda (LMA está freqüentemente associada a translocações cromossômicas recorrentes. Em muitos casos, os genes presentes nos pontos de quebra cromossômica são conhecidos e, quase todos codificam para fatores de transcrição. O gene híbrido, resultante da justaposição de exons de genes distintos, codifica para proteínas de fusão. Como estas retêm a maior parte dos domínios funcionais das proteínas selvagens, elas interferem direta ou indiretamente com regulação da transcrição gênica, conferindo vantagem à sobrevivência das células leucêmicas. A maioria dos fatores de transcrição afetados pelas translocações cromossômicas associadas a LMA pode ser agrupada numa das seguintes famílias: dos core binding factors (CBF, do receptor

  3. C cells in the thyroid of pinealectomized rats Células C em tireóides de ratos pinealectomisados

    Directory of Open Access Journals (Sweden)

    Marcus Aurelho de Lima

    2003-01-01

    Full Text Available PURPOSE: To study quantitatively C cells in the thyroids of non-isogenic rats to determine the possible effects of pinealectomy on the number of these cells, and consequently on the synthesis and secretion of calcitonin. METHODS: Twenty male rats of an outbred strain (200-300 g were used in the present study. One group of 10 animals was pinealectomized 50 days prior to sacrifice. Thyroid tissue was stained for calcitonin (Dako Corporation at a 1:1500 dilution. The number of C cells observed was expressed as number of cells/cm². Data were analyzed statistically by Mann-Whitney test. RESULTS: The number of C cells in pinealectomized and normal animals ranged from 489 to 2084 per cm² and 227 to 1584 per cm², respectively, a difference that was statistically significant (P OBJETIVO: Estudar quantitativamente células C de tireóides em ratos não isogênicos para determinar os possíveis efeitos da pinealectomia no número destas células e conseqüentemente na síntese e secreção de calcitonina. MÉTODO: Vinte ratos machos com peso de 200 a 300g foram utilizados no presente estudo. Um grupo de 10 animais foi pinealectomizado 50 dias antes do sacrifício. Os cortes de tireóide foram corados com calcitonina (DAKO Corporation a diluição de 1:1500. O número de células C observado é expresso como número de células/cm². Os dados foram analisados pela análise de variância (ANOVA e teste Mann-Whitney. RESULTADOS: O número de células C em animais pinealectomizados e normais variou de 489 a 2084 células/cm² e 227 a 1584 células/cm², respectivamente. CONCLUSÕES: Estes resultados mostraram diferenças consistentes (p<0,05 no número de células C após a pinealectomia quando comparada aos controles. Nós acreditamos que a pinealectomia aumenta o número de células C nas tireóides dos ratos.

  4. Ukrainische Musik. Idee und Geschichte einer musikalischen Nationalbewegung in ihrem europäischen Kontext, Lipsko, 7.-9. května 2006

    Czech Academy of Sciences Publication Activity Database

    Bajgarová, Jitka

    2006-01-01

    Roč. 43, č. 2 (2006), s. 215-216 ISSN 0018-7003. [Ukrainische Musik . Idee und Geschichte einer musik alischen Nationalbewegung in ihrem europäischen Kontext. Lipsko, 07052006-09052006] Institutional research plan: CEZ:AV0Z90580513 Keywords : Ukrainian music culture * European context Subject RIV: AL - Art, Architecture, Cultural Heritage

  5. Análise da pluviosidade e do efeito de borda sobre os teores de flavonóides em Bauhinia cheilantha (Bong. Steud., Fabaceae

    Directory of Open Access Journals (Sweden)

    Tadeu J. da S. Peixoto Sobrinho

    Full Text Available Este estudo avaliou a influência do efeito de borda e da pluviosidade sobre a produção de flavonóides em indivíduos de Bauhinia cheilantha (Bong. Steud., Fabaceae, em uma área de caatinga no estado de Pernambuco, Nordeste do Brasil. Foi utilizada metodologia analítica por complexação com cloreto de alumínio para quantificar a concentração de flavonóides contidos nos extratos foliares de B. cheilantha, por meio de espectrofotometria no visível. De forma geral, o efeito de borda afeta a produção de flavonóides, entretanto, não foi possível correlacionar a produção de flavonóides e a pluviosidade, demonstrando que a espécie avaliada utiliza outra estratégia como resposta às pressões ambientais.

  6. A análise do nível superficial da narrativa do filme "BLADE RUNNER: O CAÇADOR DE ANDRÓIDES de Ridley Scott"

    Directory of Open Access Journals (Sweden)

    Anna Maria Balogh

    1985-05-01

    Full Text Available No trabalho que apresentamos aqui, pretendemos testar a aplicabilidade do modelo de análise narrativa proposto pelo Groupe d'Entrevernes ("Analyse Semiotique des Textes" a um objeto fílmico específico: "BLADE RUNNER: 0 CAÇADOR DE ANDRÓIDES".

  7. La tradizione nella scienza il progresso scientifico come equilibrio dialettico tra idee innovatrici e tradizione in una raccolta di saggi inediti

    CERN Document Server

    Heisenberg, Werner

    1982-01-01

    In questa raccolta di saggi (inediti per l'Italia), da lui stesso selezionati poco prima della morte, Heisenberg analizza da varie angolazioni i rapporti tra progresso scientifico e tradizione : la storia della scienza è soprattutto una storia di idee, e da un giusto equilibrio dialettico tra i nuovi concetti e la tradizione, che costituisce la base ideale per discuterli, scaturisce il progress scientifico.

  8. Tagasipöördumine ja taktika : mängu idee 1960. aastate eesti kultuuris ja happening "Mannekeeni matmine" / Anu Allas

    Index Scriptorium Estoniae

    Allas, Anu, 1977-

    2008-01-01

    Analüüsitakse ideed mängust kui loomingumeetodist ja sotsiaalse surutise leevendajast 1960. aastate eesti kultuuris, keskendudes korraldatud häppeningidele, mille loomisel on toetutud Tartu nn. teatriuuenduse meetoditele ja mille aluseks on Roger Caillois' kultuurilooline mänguteooria. Pikemalt Leonhard Lapini, Andres Toltsi ja Ando Keskküla korraldatud rituaalsest etteastest "Mannekeeni matmine" Kablis

  9. Tratamento cirúrgico das fraturas do odontóide tipo II com parafuso anterior: análise de 15 casos

    Directory of Open Access Journals (Sweden)

    Dantas Fernando Luiz Rolemberg

    2002-01-01

    Full Text Available Apresentamos estudo retrospectivo dos resultados de 15 pacientes consecutivos, com fratura do odontóide tipo II P (fratura com traço oblíquo e deslocamento posterior e II N (fratura com traço horizontal na base do odontóide, segundo a classificação de Roy-Camille , que foram submetidos a fixação anterior direta do odontóide com parafuso. A série é composta por 13 homens e 2 mulheres, com idade variando entre 14 a 74 anos e período de acompanhamento de 6 a 36 meses (média 20 meses. Tivemos apenas uma complicação relacionada com a técnica cirúrgica: um parafuso mal posicionado necessitando de uma reoperação para ser reposicionado. Não houve óbito. Não houve saída nem quebra de parafuso. Obteve-se 94% de fusão óssea. Propomos que seja utilizada a classificação de Roy-Camille na seleção dos casos cirúrgicos de fraturas do odontóide, pois ela fornece uma abordagem cirúrgica específica para cada tipo de fratura.

  10. Exclusion, exemption and clearance in the mining and minerals industry - A review of the concepts from a South African perspective

    International Nuclear Information System (INIS)

    Selby, J.H.

    1997-01-01

    The risks from mining and processing of ores is reviewed on a generic basis with particular reference to some of the confusions which can arise due to lack of consistency or common logic in the use of exclusion, exemption and clearance. The difference in exclusion and exemption are challenged by comparing doses received in high background radiation areas and the doses received from a mining practice. The common principle of risk to the human species is not applied consistently. The differences between IAEA recommendations and local regulatory conditions are compared, and the use of exemption levels as clearance levels is considered. A case study on management of mine tailings is presented with special focus on the use of clearance levels. In all areas of review the interpretation of regulation is subject to confusion resulting from inconsistencies which can distort free market economics. (author)

  11. Tax-exempt bank loans still an option for providers.

    Science.gov (United States)

    Ostlund, Grant; Cheney, John E

    2011-07-01

    In evaluating the potential for tax-exempt bank financing, healthcare organizations should carefully consider: Pricing. Loan structure. Security requirements (such as financial covenants and default remedies).

  12. 77 FR 10607 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-02-22

    ...-2011-0367] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce. The...). [[Page 10608

  13. L'evoluzione della fisica sviluppo delle idee dai concetti iniziali alla relatività e ai quanti

    CERN Document Server

    Einstein, Albert

    1965-01-01

    Pubblicato in inglese alla vigilia della Seconda guerra mondiale e subito proposto in traduzione, L’evoluzione della fisica dovette aspettare la fine del conflitto per vedere la sua pubblicazione in Italia. Da allora (1948) questo testo non ha più smesso di rappresentare un punto di riferimento obbligato per il concetto stesso di divulgazione scientifica e per la fisica in particolare. Scritto dai protagonisti assoluti della rivoluzione della fisica relativistica e quantistica, ma destinato a un pubblico di non specialisti, il libro che avete tra le mani è il testo fondativo della moderna divulgazione delle idee, la pietra di paragone di ogni altro libro di fisica, che permette di intuire la straordinaria importanza e il valore rivoluzionario della svolta della fisica del Novecento.

  14. Diplóides (AA de bananeira submetidos ao estresse salino Banana diploids (AA submitted to salt stress

    Directory of Open Access Journals (Sweden)

    Eline Waked Ferreira Gomes

    2004-06-01

    Full Text Available No Nordeste do Brasil a salinização dos solos é um dos fatores limitantes na produção de bananeira. Estudos quanto à tolerância à salinidade em diplóides de bananeira são importantes para programas de melhoramento genético. Esse trabalho objetivou avaliar os efeitos da salinidade utilizando variáveis químicas e de crescimento, e quantificar, mediante padrões isoenzimáticos, a diversidade genética entre seis genótipos diplóides (AA, associando-os à tolerância à salinidade. As plantas foram tratadas durante 21 dias com 0, 50 e 100 mM de NaCl, num delineamento experimental inteiramente casualizado. Os diplóides Lidi e Calcuttá apresentaram maiores reduções na área foliar e fortes sintomas de toxidez associados aos maiores acúmulos de Na+ e Cl- no limbo. Os genótipos Borneo e SNº/2 apresentaram discretos sintomas de toxidez e, como o genótipo M-53, demonstraram habilidade de evitar a translocação excessiva de Na+ e Cl- para as folhas preservando o aparelho fotossintético. Nos diplóides SNº/2 e M-53 foi detectada uma banda específica (Po-6 do sistema peroxidase, sob condições de estresse salino. Associando as características isoenzimáticas com as de crescimento, sintomatologia, análise mineral e grau de similaridade genética entre os genótipos, os dendrogramas construídos separam os genótipos mais tolerantes (SNº/2 e M-53 dos mais sensíveis (Lidi e Calcuttá.In the Northeast Region of Brazil, salinization in soils is one of the limiting factors for banana production. Studies regarding tolerance and salt sensitivity in banana diploids are important for genetic breeding programs. This work aimed to evaluate salt stress effects measuring growth and chemicals parameters and to quantify the genetic diversity among six diploids (AA genotypes using isozymic standards relating to salt tolerance. The plants were treated during 21 days under 0, 50 and 100 mM of NaCl in a completely randomized design. The diploids

  15. O ideário taylorista, a gestão da subjetividade e o poder pastoral

    Directory of Open Access Journals (Sweden)

    Bruno Eduardo Procopiuk Walter

    Full Text Available Este ensaio tem por objetivo analisar o ideário taylorista concernente à relação entre operários e gestores a partir da categoria do poder pastoral, proposta por Michel Foucault. Se o poder disciplinar incide sobre o corpo, o poder pastoral incide sobre a alma do indivíduo, implicando - por meio de técnicas confessionais - a direção de consciência. No âmbito do taylorismo, pode-se concluir, tal poder se manifesta, mas não com um sentido parhesiastico, revelando no taylorismo um processo de configuração de verdades a respeito do sujeito operário, ou trabalhador, que o coloca em condição de objeto da gestão nas relações estabelecidas entre a gestão e o operário.

  16. Observação de anemia hemolítica auto-imune em artrite reumatóide

    OpenAIRE

    Souza,Ricardo A. S.; Souza,Henrique F. S.; Rangel,Leandro V.; Nogueira,Luciana V. A.; Santiago,Mittermayer B.

    2003-01-01

    Artrite reumatóide é uma doença difusa do tecido conjuntivo que se caracteriza pelo acometimento articular e sistêmico. Disfunções hematológicas como anemia ocorrem em até 65% dos pacientes, sendo a anemia das doenças crônicas a forma mais comum. A anemia hemolítica auto-imune pode estar associada à difusa do tecido conjuntivo, sendo classicamente associada ao lúpus eritematoso sistêmico e fazendo parte dos seus critérios de classificação. A presença de anemia hemolítica auto-imune em artrite...

  17. Concomitância da tireoidite de Hashimoto e o carcinoma diferenciado da tireóide

    OpenAIRE

    Roberti, Alexandre; Andrade Sobrinho, Josias de; Denardin, Odilon Victor Porto; Rapoport, Abrão

    2006-01-01

    OBJETIVO: Avaliar a associação da tireoidite auto-imune e o carcinoma diferenciado da tireóide na Santa Casa de Misericórdia de Goiânia-Goiás. MÉTODO: De 1395 tireoidectomias realizadas de 1994 a 2003, foram selecionadas 120 carcinomas diferenciados (27 foliculares e 93 papilíferos). Foram avaliadas as variáveis clínicas (idade e sexo) com apresentação de freqüências e de sumários de medidas-resumo na descrição estatística. Para aferir a associação de tireoidite auto-imune e carcinoma diferen...

  18. Acesso endoscópico transepto-interforniceal para cistos colóides: relato de caso

    Directory of Open Access Journals (Sweden)

    VIALOGO JOSUÉ GUIMARÃES GRANHA

    2000-01-01

    Full Text Available A abordagem endoscópica de cistos colóides ainda é matéria controversa. As opções de tratamento são variadas: observação com exames seriados, tratamento da hidrocefalia, aspiração por estereotaxia, microcirurgia e endoscopia. O autor relata o caso de um paciente com cisto colóide do terceiro ventrículo, localizado em posição retroforaminal, no teto diencefálico, dissecando os dois fornices projetando-se supero-posteriormente em direção ao assoalho do ventrículo lateral, por dentro do cavum do septo pelúcido. A lesão foi alcançada com neuroendoscópio rígido, através de um orifício de trépano pré-coronal situado a 2,5 cm da linha média (ponto de Kocher. Seguindo por via transventricular, a lâmina direita do septo pelúcido foi aberta, posterior à veia septal. A lesão, muito endurecida, situada entre os dois fórnices, foi parcialmente ressecada através da via endoscópica transventricular transepto-interforniceal. Realizamos também septostomia e terceiro ventriculostomia endoscópicas neste paciente. Os diferentes tipos de procedimentos cirúrgicos das patologias situadas no terceiro ventrículo são discutidos com ênfase no papel da endoscopia.

  19. APLICAÇÃO DA FONOFORESE NO TRATAMENTO DO FIBRO EDEMA GELÓIDE NA REGIÃO ABDOMINAL

    Directory of Open Access Journals (Sweden)

    Ohanna Daher de Paula FELIPE

    2015-12-01

    Full Text Available O objetivo desta pesquisa foi analisar os efeitos do ultrassom terapêutico de 3MHz associado a fonoforese na redução do fibro edema gelóide na região abdominal. Para tal realizou-se uma pesquisa experimental do tipo estudo de caso. O estudo foi realizado com uma paciente do sexo feminino, de30anos, com quadro de FEG graus 1 e 2 na região abdominal. Foram utilizados uma ficha de avaliação específica para fibro edema gelóide e registro fotográfico. A paciente foi submetida a 20 sessões de tratamento, realizando 3 vezes por semana, com duração de 24 minutos de ultrassom. O protocolo do US utilizado neste estudo foi frequência de 3 MHz, com intensidade de 0,6 w/cm², modo contínuo, associado a fonoforese com uma substância de acoplamento, em forma de gel, composto por arnica, algas marinhas, centella asiática, castanha da índia, cavalhinha, hera, erva mate, laranja amarga, chá verde, gengibre e L-carnitina, fabricado pela Buonavita cosméticos. Ao final do tratamento foi possível observar melhora no quadro de FEG, melhora no aspecto da pele e satisfação da paciente com os resultados. Com isso, conclui-se que o ultrassom associado à fonoforese pode ser benéfico no tratamento do FEG, provando ser um recurso eficaz na diminuição do aspecto do mesmo.

  20. Opióides no manejo da dor - uso correto ou subestimado? Dados de um hospital universitário

    Directory of Open Access Journals (Sweden)

    Daudt A.W.

    1998-01-01

    Full Text Available OBJETIVO: O uso de opióides, principalmente no tratamento da dor intensa aguda (pacientes no pós-operatório e da dor crônica em pacientes oncológicos, tem sido subestimado na prática clínica em geral. Este trabalho tem o objetivo de verificar o perfil de prescrição de opióides (meperidina e morfina no Hospital de Clínicas de Porto Alegre (HCPA, RS. MATERIAIS E MÉTODOS: Análise da conduta das equipes médicas, pela revisão de 1.107 prescrições, relativas a 445 pacientes internados no HCPA, entre 20 de maio e 20 de julho de 1993. Os parâmetros básicos de análise, para conduta, incluíam: padrão de uso, a dose do fármaco, intervalo entre doses e analgésicos simultâneos. DISCUSSÃO E RESULTADOS: Foram encontradas apenas 6,5% de prescrições consideradas adequadas em relação aos parâmetros dose, intervalo e padrão, analisados conjuntamente. O padrão se necessário foi responsável por 74% do total de prescrições. CONCLUSÕES: Os resultados obtidos durante a realização do trabalho permitem-nos concluir que não há um manejo adequado da dor, tanto aguda como crônica, nos pacientes internados no HCPA.

  1. O papel da imunofluorescência direta na fisiopatologia e no diagnóstico diferencial da estomatite aftóide recorrente The role of immunoflorescence in the physiopathology and differential diagnosis of recurrent aphthous stomatitis

    Directory of Open Access Journals (Sweden)

    Niels Salles Willo Wilhelmsen

    2008-06-01

    Full Text Available A estomatite aftóide recorrente é doença caracterizada por aparecimento periódico de aftas na mucosa oral, cuja etiologia e fisiopatologia não estão bem explicadas. Estudos recentes com imunofluorescência direta mostram resultados controversos. Alguns revelam que o distúrbio básico está relacionado à imunidade humoral, enquanto outros apontam alterações da imunidade celular. Formas atípicas de estomatite aftóide podem fazer diagnóstico diferencial com doenças vésico-bolhosas como pênfigo vulgar. OBJETIVO: Verificar a presença de imunecomplexos na mucosa de pacientes com estomatite aftóide e utilidade do método no diagnóstico diferencial com dermatopatias bolhosas. CASUÍSTICA E MÉTODO: 23 pacientes portadores de estomatite aftóide, de modo prospectivo, foram incluídos no estudo. Todos foram submetidos à biópsia de mucosa sob anestesia local para retirada de dois fragmentos. Um deles foi enviado para exame histológico e, outro, para ser realizada a imunofluorescência direta. RESULTADOS: As 23 amostras no exame histológico revelaram processo inflamatório inespecífico ulcerado. As amostras enviadas para imunofluorescência resultaram negativas e apenas uma revelou presença de complemento em membrana basal. CONCLUSÃO: Baseado em nossos resultados, concluímos que pacientes portadores de EAR não apresentam depósitos de imunecomplexos na mucosa da cavidade bucal e a imunofluorescência é útil no diagnóstico diferencial entre a doença e dermatopatias bolhosas.Recurrent aphthous stomatitis (RAS is a disease characterized by the periodic appearance of aphthous lesions on the oral mucosa, of which etiology and physiopathology are not well explained. Recent studies with direct immunofluorescence show controversial results. Some reveal that the basic disorder is associated with humoral immunity, while others point to changes in cellular immunity. Atypical forms of aphthous stomatitis may have its differential

  2. Leucemia linfóide aguda: uma doença curável Acute lymphoblastic leukemia: a curable disease

    Directory of Open Access Journals (Sweden)

    Francisco Pedrosa

    2002-04-01

    Full Text Available RESUMO: Leucemia linfóide Aguda (LLA, é o tipo mais comum de câncer infantil, constituindo cerca de um terço de todas as neoplasias malignas da criança. A incidência de LLA em crianças nos Estados Unidos é aproximadamente de 3,4 casos por 100.000 crianças menores de 15 anos de idade. Até a metade do século passado, as leucemias eram consideras universalmene, uma doença fatal. O desenvolvimento de combinações terapêuticas, utilizando diversas drogas citotóxicas com ou sem transplante de medula óssea, tem aumentado o percentual de cura da criança portadora de Leucemia linfóide Aguda em mais de 80%. Anualmente cerca de 1.500 crianças com LLA, nos Estados Unidos, estão sendo curadas. Contudo, dos 75.000 novos casos de LLA, que são diagnosticados anualmente em todo o mundo, cerca de 60.000 (80% não têm acesso a essas modernas formas de tratamento e são, portanto excluídos desse processo de cura. O desafio de tornar a LLA uma doença curável começa a ser vencido com o relato de taxas de sobrevida maior que 50% para crianças tratadas em países com recursos limitados. Em El salvador, Bonilla, conseguiu aumentar a taxa de sobrevida de crianças com LLA de 5% para 50%. No Recife, Pernambuco, Brasil, Pedrosa evoluiu de uma taxa de 29% nos anos 80, para 75% na era atual.ABSTRACT: Acute lymphoblastic leukemia (ALL is the most common type of cancer in children, accoun-ting for one third of all malignant neoplasias affecting them. ALL incidences in children in the United States are of approximately 3,4 cases per 100.000 children under fifteen years old. Up to the middle of last century leukemia was universally considered a fatal di-sease. The development of therapeutic combinations through the use of various cytotoxic drugs with or without bone marrow transplantation has increased cure percentages of children with ALL in over 80%. Annually around 1.500 children with ALL in the Uni-ted States are being cured. Nevertheless, of the

  3. Mecanismos de ação dos corticosteróides na polipose rinossinusal Mechanism of action of glucocorticoids in nasal polyposis

    Directory of Open Access Journals (Sweden)

    Atílio Maximino Fernandes

    2008-04-01

    Full Text Available Os glicocorticóides (GC são drogas de escolha no tratamento clínico da polipose nasossinusal conforme recomendação da literatura. Entretanto, seus mecanismos de ação nas regressões dos sintomas clínicos e dos pólipos não são totalmente compreendidos. Sabe-se que a administração tópica e ou sistêmica dos glicocorticóides leva a variações na expressão de citocinas, quimiocinas e linfocinas, além das alterações celulares. Assim, os GC suprimem a expressão de citocinas pró-inflamatórias, de quimiocinas, de moléculas de adesão, além de estimular a transcrição de citocinas antiinflamatórias. Citocinas pró-fibróticas como a IL-11, fator básico de crescimento do fibroblasto (b-FGF e fator de crescimento endotelial vascular (VEGF, relacionados com o crescimento do pólipo, também são suprimidos pela ação do GC. Tal ação depende fundamentalmente da interação com os seus receptores (GR, pois alguns indivíduos apresentam algum grau de resistência celular ao seu efeito, que parece estar relacionada com a presença da isoforma b do GR. Genes envolvidos nas fases de produção de imunoglobulinas, apresentação e processamento do antígeno também sofrem ação dos GC de forma variada. OBJETIVOS: Fazer uma revisão da literatura sobre os mecanismos de ação do GC na PNS. CONCLUSÃO: A compreensão desses mecanismos implicará no desenvolvimento de drogas mais eficazes na sua terapêutica.Glucocorticoids (GC are the drugs of choice for the clinical treatment of nasal polyposis, according to the medical literature. Its mechanism of action in the regression of clinical symptoms and polyps, however, is not fully understood. The topical and/or systemic use of glucocorticoids lead to variable expression of cytokines, chemokines and lymphokines, as well as changes in cells. It is known that GC suppresses the expression of pro-inflammatory cytokines, chemokines and adhesion molecules such as ICAM-1 and E-selectin; GC also

  4. Diversidade e aspectos ecológicos de fungos gasteróides (Basidiomycota) em quatros áreas de Mata Atlântica no Estado de Pernambuco, Brasil

    OpenAIRE

    Trierveliler Pereira, Larissa

    2011-01-01

    Os fungos gasteróides são caracterizados principalmente pelo basidioma angiocárpico e liberação passiva dos basidiosporos. Até o momento, 232 espécies de fungos gasteróides estão registradas para o Brasil, sendo que o conhecimento do grupo vem aumentando desde o início do século XXI. Com o objetivo de conhecer melhor estes organismos no Brasil, a diversidade e aspectos ecológicos de fungos gasteróides foram investigados em quatro remanescentes de Mata Atlântica no estado de Per...

  5. L’impact des (IDE) sur la croissance économique dans les pays : [Maroc-Algérie-Tunisie] entre la période 1990-2009 (Etude comparative & Modélisation économétrique)

    OpenAIRE

    Khalfallah, Saddek

    2014-01-01

    Le premier chapitre, passe rapidement en revue les définitions et les principaux concepts relatifs à l’investissement direct étranger. Le deuxième chapitre présente, l’évolution des (IDE), et la croissance économique dans les pays [M/A/T], depuis les années 1990 jusqu’à 2009. Le chapitre trois teste avec robustesse les effets des (IDE) sur la croissance èconomique, nous envisageons la un modèle structurel, construit pour apprécier les effets des (IDE) sur le transfert de compétenc...

  6. 18 CFR 4.106 - Standard terms and conditions of case-specific exemption from licensing.

    Science.gov (United States)

    2010-04-01

    ... LICENSES, PERMITS, EXEMPTIONS, AND DETERMINATION OF PROJECT COSTS Exemption of Small Hydroelectric Power... licensing. Any case-specific exemption from licensing granted for a small hydroelectric power project is... falsehoods were made by or on behalf of the applicant. (h) Article 8. Any exempted small hydroelectric power...

  7. 40 CFR 180.1263 - Tetrahydrofurfuryl alcohol; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... FOOD Exemptions From Tolerances § 180.1263 Tetrahydrofurfuryl alcohol; exemption from the requirement of a tolerance. Tetrahydrofurfuryl alcohol (THFA, CAS Reg. No. 97-99-4) is exempt from the... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Tetrahydrofurfuryl alcohol; exemption...

  8. 75 FR 15642 - Schedules of Controlled Substances: Exempted Prescription Product; River Edge Pharmaceutical...

    Science.gov (United States)

    2010-03-30

    ... 1117-AB28 Schedules of Controlled Substances: Exempted Prescription Product; River Edge Pharmaceutical... new applications for exemption. DEA has received one new application for exemption for River Edge... application for exemption pursuant to the provisions of 21 CFR 1308.32 for: River Edge Pharmaceutical's...

  9. 40 CFR 180.1290 - Pasteuria usgae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pasteuria usgae; exemption from the... Exemptions From Tolerances § 180.1290 Pasteuria usgae; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of Pasteuria usgae in or on all...

  10. 40 CFR 180.1135 - Pasteuria penetrans; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pasteuria penetrans; exemption from... FOOD Exemptions From Tolerances § 180.1135 Pasteuria penetrans; exemption from the requirement of a tolerance. The biological nematicide Pasteuria penetrans is exempted from the requirement of a tolerance in...

  11. 40 CFR 180.1232 - Lime-sulfur; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lime-sulfur; exemption from the... Exemptions From Tolerances § 180.1232 Lime-sulfur; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of lime-sulfur. [70 FR 33363, June...

  12. 40 CFR 180.1145 - Pseudomonas syringae; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pseudomonas syringae; exemption from... FOOD Exemptions From Tolerances § 180.1145 Pseudomonas syringae; exemption from the requirement of a tolerance. Pseudomonas syringae is exempted from the requirement of a tolerance on all raw agricultural...

  13. 40 CFR 180.1111 - Bacillus subtilis GB03; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus subtilis GB03; exemption from... FOOD Exemptions From Tolerances § 180.1111 Bacillus subtilis GB03; exemption from the requirement of a tolerance. The biofungicide Bacillus subtilis GB03 is exempted from the requirement of a tolerance in or on...

  14. 40 CFR 180.1054 - Calcium hypochlorite; exemptions from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Calcium hypochlorite; exemptions from... FOOD Exemptions From Tolerances § 180.1054 Calcium hypochlorite; exemptions from the requirement of a tolerance. (a) Calcium hypochlorite is exempted from the requirement of a tolerance when used preharvest or...

  15. 40 CFR 180.1040 - Ethylene glycol; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Ethylene glycol; exemption from the... Exemptions From Tolerances § 180.1040 Ethylene glycol; exemption from the requirement of a tolerance. Ethylene glycol as a component of pesticide formulations is exempt from the requirement of a tolerance when...

  16. 40 CFR 180.1273 - Beauveria bassiana HF23; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Beauveria bassiana HF23; exemption... FOOD Exemptions From Tolerances § 180.1273 Beauveria bassiana HF23; exemption from the requirement of a tolerance. Residues of Beauveria bassiana HF23 are exempt from the requirement of a tolerance on all food...

  17. 40 CFR 180.1160 - Jojoba oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Jojoba oil; exemption from the... Exemptions From Tolerances § 180.1160 Jojoba oil; exemption from the requirement of a tolerance. The insecticide and spray tank adjuvant jojoba oil is exempted from the requirement of a tolerance in or on all...

  18. 40 CFR 180.1187 - L-glutamic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false L-glutamic acid; exemption from the... Exemptions From Tolerances § 180.1187 L-glutamic acid; exemption from the requirement of a tolerance. L-glutamic acid is exempt from the requirement of a tolerance on all food commodities when used in accordance...

  19. 40 CFR 180.1119 - Azadirachtin; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Azadirachtin; exemption from the... Exemptions From Tolerances § 180.1119 Azadirachtin; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for the biochemical azadirachtin, which is...

  20. 40 CFR 180.1241 - Eucalyptus oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Eucalyptus oil; exemption from the... Exemptions From Tolerances § 180.1241 Eucalyptus oil; exemption from the requirement of a tolerance. Time-limited exemptions from the requirement of a tolerance are established for residues of eucalyptus oil on...

  1. 40 CFR 180.1271 - Eucalyptus oil; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Eucalyptus oil; exemption from the... Exemptions From Tolerances § 180.1271 Eucalyptus oil; exemption from the requirement of a tolerance. An exemption from the requirement of tolerance is established for residues of eucalyptus oil in or on honey...

  2. 40 CFR 180.1262 - Sorbitol octanoate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sorbitol octanoate; exemption from the... Exemptions From Tolerances § 180.1262 Sorbitol octanoate; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of sorbitol octanoate in or on all...

  3. 40 CFR 180.1090 - Lactic acid; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Lactic acid; exemption from the... Exemptions From Tolerances § 180.1090 Lactic acid; exemption from the requirement of a tolerance. Lactic acid (2-hydroxypropanoic acid) is exempted from the requirement of a tolerance when used as a plant growth...

  4. 76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Science.gov (United States)

    2011-09-09

    .... Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 6649-008. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  5. 76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Science.gov (United States)

    2011-09-20

    .... Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 6649-008. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  6. 77 FR 73653 - Milburnie Hydro Inc.; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Science.gov (United States)

    2012-12-11

    ... Inc.; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 7910-006. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  7. 76 FR 37880 - Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA)

    Science.gov (United States)

    2011-06-28

    ...-28043] Hours of Service (HOS) of Drivers; Granting of Exemption; American Pyrotechnics Association (APA... exemption from the American Pyrotechnics Association (APA) on behalf of 9 member motor carriers seeking... such exemption'' (49 U.S.C. 31315(b)(1)). The initial APA application for waiver or exemption relief...

  8. 40 CFR 180.1234 - Sodium carbonate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Sodium carbonate; exemption from the... Exemptions From Tolerances § 180.1234 Sodium carbonate; exemption from the requirement of a tolerance. An exemption from the requirement of a tolerance is established for residues of sodium carbonate. [70 FR 33363...

  9. 17 CFR 250.4 - Exemption of certain brokers, dealers and underwriters.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Exemption of certain brokers... and General Exemptions § 250.4 Exemption of certain brokers, dealers and underwriters. (a) General exemption. Subject to the provision of § 250.6, any broker, dealer or underwriter, as defined in paragraph...

  10. 40 CFR 180.1189 - Methyl salicylate; exemption from the requirement of a tolerance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Methyl salicylate; exemption from the... Exemptions From Tolerances § 180.1189 Methyl salicylate; exemption from the requirement of a tolerance. The biochemical pesticide methyl salicylate is exempt from the requirement of a tolerance for residues in or on...

  11. 17 CFR 230.238 - Exemption for standardized options.

    Science.gov (United States)

    2010-04-01

    ... options. 230.238 Section 230.238 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... Exemption for standardized options. (a) Exemption. Except as expressly provided in paragraphs (b) and (c) of this section, the Act does not apply to any standardized option, as that term is defined by section 240...

  12. 22 CFR 123.16 - Exemptions of general applicability.

    Science.gov (United States)

    2010-04-01

    ... United States, by accredited U.S. institutions of higher learning of articles fabricated only for... FOR THE EXPORT OF DEFENSE ARTICLES § 123.16 Exemptions of general applicability. (a) The following exemptions apply to exports of unclassified defense articles for which no approval is needed from the...

  13. 5 CFR 2502.18 - Deletion of exempted information.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Deletion of exempted information. 2502.18... Charges for Search and Reproduction § 2502.18 Deletion of exempted information. Where requested records... the remainder of the records, they shall be disclosed by the Office with deletions. To each such...

  14. 29 CFR 1610.20 - Deletion of exempted matters.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Deletion of exempted matters. 1610.20 Section 1610.20 Labor... Production or Disclosure Under 5 U.S.C. 552 § 1610.20 Deletion of exempted matters. Where requested records... the remainder of the records, they shall be disclosed by the Commission with deletions. To each such...

  15. 19 CFR 148.46 - Sale of exempted articles.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Sale of exempted articles. 148.46 Section 148.46... exempted articles. (a) Sale resulting in forfeiture. The following articles or their value (to be recovered... paragraph (b) of this section is followed: (1) Any jewelry or similar articles of personal adornment having...

  16. 18 CFR 4.102 - Surrender of exemption.

    Science.gov (United States)

    2010-04-01

    ... OF PROJECT COSTS Exemption of Small Hydroelectric Power Projects of 5 Megawatts or Less § 4.102... hydroelectric power project must file a petition with the Commission. (b)(1) If construction has begun, prior to... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Surrender of exemption...

  17. 19 CFR 148.53 - Exemption for tools of trade.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Exemption for tools of trade. 148.53 Section 148.53 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... tools of trade. (a) Exemption. Professional books, implements, instruments, or tools of trade...

  18. 78 FR 62935 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-10-22

    ..., his optometrist noted, ``Mr. Smith, despite having a prosthetic left eye, has fully functional vision...-0166] Qualification of Drivers; Exemption Applications; Vision AGENCY: Federal Motor Carrier Safety... announces receipt of applications from 26 individuals for exemption from the vision requirement in the...

  19. 76 FR 737 - Tobacco Products, Exemptions From Substantial Equivalence Requirements

    Science.gov (United States)

    2011-01-06

    ... exemptions would be requested for an unknown number of the remaining products. Although in theory the maximum... place, only 50 exemption requests will be submitted per year. This may increase over time as learning..., and social science occupations ($30.91), architecture and engineering occupations ($40.93), and legal...

  20. 41 CFR 109-39.106 - Unlimited exemptions.

    Science.gov (United States)

    2010-07-01

    ..., AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 109-39.106 Unlimited exemptions. The Director, Office of... determination that an unlimited exemption from inclusion of a motor vehicle in a fleet management system is...

  1. 24 CFR 1710.10 - Single-family residence exemption.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Single-family residence exemption... Requirements § 1710.10 Single-family residence exemption. (a) General. The sale of a lot which meets the...) Lot dimensions. (ii) Plat approval and recordation. (iii) Roads and access. (iv) Drainage. (v...

  2. 75 FR 44049 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-07-27

    .... Koegel, Nicholas J. Niemerg, Dereck J. Oliveira, Paul J. O'Neil, Jr., Worden T. Price, Frankie R. Ramey... the twenty-five exemption applications, FMCSA exempts, Calvin R. Adams, Michael R. Amstutz, Clinton R. Carlson, II, Brandon L. Cheek, Michael J. Drake, Richard A. Dufton, Jr., Kenneth Dunn, Robert J. Dyxin...

  3. 48 CFR 1329.203-70 - DOC Federal tax exemption.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOC Federal tax exemption... CONTRACTING REQUIREMENTS TAXES Federal Excise Taxes 1329.203-70 DOC Federal tax exemption. (a) The Office of... enabling DOC and its contractors to purchase spirits (e.g., specially denatured spirits) tax-free for non...

  4. 75 FR 80106 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-12-21

    ... training facilities requirements given the school's use of online training material, as well as the ground...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition...

  5. 75 FR 20881 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-04-21

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  6. 76 FR 33807 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-06-09

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  7. 76 FR 39976 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-07-07

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATE: Comments on this petition must...

  8. 75 FR 60859 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-10-01

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  9. 77 FR 35103 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-06-12

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  10. 78 FR 17746 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-03-22

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  11. 78 FR 53185 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-08-28

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  12. 77 FR 36333 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-06-18

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  13. 75 FR 19672 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-04-15

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... summary is intended to affect the legal status of the petition or its final disposition. DATES: Comments...

  14. 78 FR 46673 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-08-01

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  15. 78 FR 57676 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-09-19

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  16. 75 FR 60164 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-09-29

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  17. 76 FR 65772 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-10-24

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  18. 78 FR 53186 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-08-28

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATE: Comments on this petition must...

  19. 76 FR 16653 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-03-24

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  20. 78 FR 56768 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-09-13

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  1. 75 FR 26839 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-05-12

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  2. 77 FR 2120 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-01-13

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  3. 78 FR 73918 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-12-09

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... summary is intended to affect the legal status of the petition or its final disposition. [[Page 73919...

  4. 78 FR 13745 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-02-28

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  5. 78 FR 13746 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-02-28

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... summary is intended to affect the legal status of the petition or its final disposition. DATES: Comments...

  6. 77 FR 58210 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-09-19

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  7. 76 FR 39975 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-07-07

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... summary is intended to affect the legal status of the petition or its final disposition. DATES: Comments...

  8. 78 FR 46672 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-08-01

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  9. 75 FR 10016 - Petition for Exemption; Summary of Petitions Received

    Science.gov (United States)

    2010-03-04

    ...] Petition for Exemption; Summary of Petitions Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of two petitions seeking relief from specified requirements of 14 CFR. The purpose of this notice is to improve the...

  10. 75 FR 65396 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-10-22

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  11. 77 FR 71865 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-12-04

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  12. 78 FR 73919 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-12-09

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  13. 78 FR 34139 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-06-06

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  14. 78 FR 978 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-01-07

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  15. 77 FR 50760 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-08-22

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  16. 76 FR 2746 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-01-14

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  17. 76 FR 14744 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-03-17

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... summary is intended to affect the legal status of the petition or its final disposition. DATES: Comments...

  18. 75 FR 21388 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-04-23

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petitions or their final disposition. DATES: Comments on these petitions must...

  19. 78 FR 36294 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-06-17

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  20. 76 FR 51119 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-08-17

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  1. 76 FR 9852 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-02-22

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  2. 75 FR 80107 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-12-21

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  3. 78 FR 979 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-01-07

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  4. 75 FR 21389 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-04-23

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petitions or their final disposition. DATES: Comments on these petitions must...

  5. 77 FR 71864 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-12-04

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATE: Comments on this petition must...

  6. 78 FR 66098 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-11-04

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  7. 75 FR 21387 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-04-23

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  8. 76 FR 24560 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-05-02

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  9. 75 FR 10016 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-03-04

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATE: Comments on this petition must...

  10. 78 FR 53818 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-08-30

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  11. 77 FR 5087 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-02-01

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  12. 75 FR 51525 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-08-20

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petitions or their final disposition. DATES: Comments on these petitions must...

  13. 78 FR 35353 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-06-12

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  14. 77 FR 44309 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-07-27

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  15. 77 FR 31064 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2012-05-24

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  16. 75 FR 26843 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2010-05-12

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of any petition or its final disposition. DATES: Comments on petitions received must...

  17. 78 FR 66986 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-11-07

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  18. 78 FR 39824 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-07-02

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... information in the summary is intended to affect the legal status of the petition or its final disposition...

  19. 78 FR 24290 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-04-24

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  20. 78 FR 66099 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-11-04

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  1. 78 FR 39825 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-07-02

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  2. 76 FR 20806 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2011-04-13

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  3. 78 FR 21701 - Petition for Exemption; Summary of Petition Received

    Science.gov (United States)

    2013-04-11

    ...] Petition for Exemption; Summary of Petition Received AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of petition for exemption received. SUMMARY: This notice contains a summary of a petition... the legal status of the petition or its final disposition. DATES: Comments on this petition must...

  4. 26 CFR 49.4253-3 - Exemption for certain organizations.

    Science.gov (United States)

    2010-04-01

    ... taxes imposed by section 4251 do not apply to amounts paid for services furnished to an international... (International Organization, etc.) funds; and that the charges are exempt from tax under section 4253(c) of the...) MISCELLANEOUS EXCISE TAXES FACILITIES AND SERVICES EXCISE TAXES Communications § 49.4253-3 Exemption for certain...

  5. 21 CFR 1309.26 - Exemption of law enforcement officials.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exemption of law enforcement officials. 1309.26 Section 1309.26 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Requirements for Registration § 1309.26 Exemption of law enforcement...

  6. 21 CFR 1301.24 - Exemption of law enforcement officials.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Exemption of law enforcement officials. 1301.24 Section 1301.24 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE REGISTRATION OF MANUFACTURERS, DISTRIBUTORS, AND DISPENSERS OF CONTROLLED SUBSTANCES Exceptions to Registration and Fees § 1301.24 Exemption of law enforcement...

  7. 48 CFR 22.604-2 - Regulatory exemptions.

    Science.gov (United States)

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.604-2 Regulatory exemptions. (a) Contracts for the following acquisitions are fully exempt from the... contractor where the stipulations of the Act were not included in the defaulted contract. (4) Newspapers...

  8. 48 CFR 22.604-1 - Statutory exemptions.

    Science.gov (United States)

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS APPLICATION OF LABOR LAWS TO GOVERNMENT ACQUISITIONS Walsh-Healey Public Contracts Act 22.604-1 Statutory exemptions. Contracts for acquisition of the following supplies are exempt from the Act: (a) Any item in those situations where the contracting officer is authorized by the express...

  9. 7 CFR 1207.514 - Exemption for organic potatoes.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption for organic potatoes. 1207.514 Section 1207... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Rules and Regulations Assessments § 1207.514 Exemption for organic potatoes. (a...

  10. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ...-0190] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... individuals listed in this notice have recently requested such an exemption from the diabetes prohibition in...

  11. 78 FR 65754 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-11-01

    ...-2013-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 23 individuals and requested...

  12. 78 FR 76400 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-17

    ...-2013-0189] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 15 individuals and requested...

  13. 78 FR 77784 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-24

    ...-2013-0184] [4910-EX-P] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY...-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate commerce... a notice of receipt of Federal diabetes exemption applications from 26 individuals and requested...

  14. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ...-0186] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... individuals listed in this notice have recently requested such an exemption from the diabetes prohibition in...

  15. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ...-0184] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs... such an exemption from the diabetes prohibition in 49 CFR 391.41(b)(3), which applies to drivers of...

  16. 78 FR 1926 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ...-2012-0347] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor... its decision to exempt 12 individuals from its rule prohibiting persons with insulin-treated diabetes....pdf . Background On October 31, 2012, FMCSA published a notice of receipt of Federal diabetes...

  17. 78 FR 1919 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-01-09

    ...-0339] Qualification of Drivers; Exemption Applications; Vision AGENCY: Federal Motor Carrier Safety... announces receipt of applications from 14 individuals for exemption from the vision requirement in the Federal Motor Carrier Safety Regulations. They are unable to meet the vision requirement in one eye for...

  18. 7 CFR 1219.202 - Exemption for organic Hass avocados.

    Science.gov (United States)

    2010-01-01

    ... defined in the Organic Act, a signed certification that the applicant meets all of the requirements... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption for organic Hass avocados. 1219.202 Section... AVOCADO PROMOTION, RESEARCH, AND INFORMATION Rules and Regulations § 1219.202 Exemption for organic Hass...

  19. 40 CFR 205.5-2 - National security exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false National security exemptions. 205.5-2... PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS General Provisions § 205.5-2 National security... a national security exemption is required. (c) For purposes of section 11(d) of the Act, any...

  20. 10 CFR 871.1 - National security exemption.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false National security exemption. 871.1 Section 871.1 Energy DEPARTMENT OF ENERGY AIR TRANSPORTATION OF PLUTONIUM § 871.1 National security exemption. (a) The following DOE air shipments of plutonium are considered as being made for the purposes of national security...

  1. 40 CFR 211.110-2 - National security exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false National security exemptions. 211.110... ABATEMENT PROGRAMS PRODUCT NOISE LABELING General Provisions § 211.110-2 National security exemptions. (a) A new product which is produced to conform with specifications developed by national security agency...

  2. 40 CFR 85.1708 - National security exemption.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 18 2010-07-01 2010-07-01 false National security exemption. 85.1708... Vehicle Engines § 85.1708 National security exemption. A manufacturer requesting a national security... agency of the Federal Government charged with responsibility for national defense. [39 FR 32611, Sept. 10...

  3. 40 CFR 204.5-2 - National security exemptions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false National security exemptions. 204.5-2... PROGRAMS NOISE EMISSION STANDARDS FOR CONSTRUCTION EQUIPMENT General Provisions § 204.5-2 National security... for a national security exemption is required. (c) For purposes of section 11(d) of the Act, any...

  4. 46 CFR 520.13 - Exemptions and exceptions.

    Science.gov (United States)

    2010-10-01

    ... AUTOMATED TARIFFS § 520.13 Exemptions and exceptions. (a) General. Exemptions from the requirements of this... for the purpose of sale. (ii) British Columbia and Puget Sound Ports; rail cars—(A) Through rates. Transportation by water of cargo moving in rail cars between British Columbia, Canada and United States ports on...

  5. 78 FR 19537 - SHINE Medical Technologies, Inc.; Exemption

    Science.gov (United States)

    2013-04-01

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0053] SHINE Medical Technologies, Inc.; Exemption AGENCY... Technologies, Inc. (SHINE) intends to submit an application to construct a medical isotope production facility... grants SHINE Medical Technologies, Inc. an exemption from the requirement of 10 CFR 2.101(a)(5) limiting...

  6. 45 CFR 5.68 - Exemption seven: Law enforcement.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exemption seven: Law enforcement. 5.68 Section 5... INFORMATION REGULATIONS Reasons for Withholding Some Records § 5.68 Exemption seven: Law enforcement. We are not required to disclose information or records that the government has compiled for law enforcement...

  7. 27 CFR 45.46 - Tax-exempt label.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Tax-exempt label. 45.46..., WITHOUT PAYMENT OF TAX, FOR USE OF THE UNITED STATES Packaging Requirements § 45.46 Tax-exempt label... Be Sold.” adequately imprinted on the package or on a label securely affixed thereto. (72 Stat. 1422...

  8. 78 FR 50486 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0182] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  9. 76 FR 79756 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-12-22

    ...-0326] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM...).\\1\\ The revision must provide for individual assessment of drivers with diabetes mellitus, and be...

  10. 77 FR 48587 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-14

    ...-0217] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  11. 77 FR 59447 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ...-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the...

  12. 78 FR 50482 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ...-0183] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  13. 77 FR 18302 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-27

    ...-0043] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... for individual assessment of drivers with diabetes mellitus, and be consistent with the criteria...

  14. 77 FR 17111 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-23

    ...-0042] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... revision must provide for individual assessment of drivers with diabetes mellitus, and be consistent with...

  15. 7 CFR 1210.516 - Exemption for organic watermelons.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Exemption for organic watermelons. 1210.516 Section... SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Rules and Regulations Assessments § 1210.516 Exemption for organic watermelons...

  16. 41 CFR 109-38.204-1 - Unlimited exemptions.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Unlimited exemptions... Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT REGULATIONS AVIATION, TRANSPORTATION... § 109-38.204-1 Unlimited exemptions. (a)-(f) [Reserved] (g) The Director, Office of Administrative...

  17. 10 CFR 871.2 - Public health and safety exemption.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Public health and safety exemption. 871.2 Section 871.2 Energy DEPARTMENT OF ENERGY AIR TRANSPORTATION OF PLUTONIUM § 871.2 Public health and safety exemption... property damage, or other significant threat to the public health and safety. [42 FR 48332, Sept. 23, 1977...

  18. New tax law hobbles tax-exempt hospitals.

    Science.gov (United States)

    Goldblatt, S J

    1982-03-01

    The Economic Recovery Tax Act of 1981 left tax-exempt hospitals at a significant disadvantage in the competition for capital. Although the new law's accelerated depreciation schedules and liberalized investment tax credits contain some marginal benefits for tax-exempt hospitals, these benefits are probably more than offset by the impact of the law on charitable giving.

  19. 49 CFR 1182.9 - Notices of exemption.

    Science.gov (United States)

    2010-10-01

    ... abuse of market power; and an exemption is in the public interest. See 49 U.S.C. 13541(a). (b) To... 49 Transportation 8 2010-10-01 2010-10-01 false Notices of exemption. 1182.9 Section 1182.9... OF TRANSPORTATION RULES OF PRACTICE PURCHASE, MERGER, AND CONTROL OF MOTOR PASSENGER CARRIERS § 1182...

  20. 41 CFR 51-9.102-1 - Specific exemptions.

    Science.gov (United States)

    2010-07-01

    ...-General Policy § 51-9.102-1 Specific exemptions. Systems of records maintained by the Committee which have... part. An individual shall have access to all exempted records containing information about him under procedures outlined in Subpart 51-9.3 of this part. Upon request, an individual shall receive an accounting...