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Sample records for exceptional diversity non-random

  1. Exceptional diversity, non-random distribution, and rapid evolution of retroelements in the B73 maize genome.

    Directory of Open Access Journals (Sweden)

    Regina S Baucom

    2009-11-01

    Full Text Available Recent comprehensive sequence analysis of the maize genome now permits detailed discovery and description of all transposable elements (TEs in this complex nuclear environment. Reiteratively optimized structural and homology criteria were used in the computer-assisted search for retroelements, TEs that transpose by reverse transcription of an RNA intermediate, with the final results verified by manual inspection. Retroelements were found to occupy the majority (>75% of the nuclear genome in maize inbred B73. Unprecedented genetic diversity was discovered in the long terminal repeat (LTR retrotransposon class of retroelements, with >400 families (>350 newly discovered contributing >31,000 intact elements. The two other classes of retroelements, SINEs (four families and LINEs (at least 30 families, were observed to contribute 1,991 and approximately 35,000 copies, respectively, or a combined approximately 1% of the B73 nuclear genome. With regard to fully intact elements, median copy numbers for all retroelement families in maize was 2 because >250 LTR retrotransposon families contained only one or two intact members that could be detected in the B73 draft sequence. The majority, perhaps all, of the investigated retroelement families exhibited non-random dispersal across the maize genome, with LINEs, SINEs, and many low-copy-number LTR retrotransposons exhibiting a bias for accumulation in gene-rich regions. In contrast, most (but not all medium- and high-copy-number LTR retrotransposons were found to preferentially accumulate in gene-poor regions like pericentromeric heterochromatin, while a few high-copy-number families exhibited the opposite bias. Regions of the genome with the highest LTR retrotransposon density contained the lowest LTR retrotransposon diversity. These results indicate that the maize genome provides a great number of different niches for the survival and procreation of a great variety of retroelements that have evolved to

  2. Exceptionally diverse morphotypes and genomes of crenarchaeal hyperthermophilic viruses

    DEFF Research Database (Denmark)

    Prangishvili, D; Garrett, R A

    2004-01-01

    and Rudiviridae. They all have double-stranded DNA genomes and infect hyperthermophilic crenarchaea of the orders Sulfolobales and Thermoproteales. Representatives of the different viral families share a few homologous ORFs (open reading frames). However, about 90% of all ORFs in the seven sequenced genomes show...... no significant matches to sequences in public databases. This suggests that these hyperthermophilic viruses have exceptional biochemical solutions for biological functions. Specific features of genome organization, as well as strategies for DNA replication, suggest that phylogenetic relationships exist between...... crenarchaeal rudiviruses and the large eukaryal DNA viruses: poxviruses, the African swine fever virus and Chlorella viruses. Sequence patterns at the ends of the linear genome of the lipothrixvirus AFV1 are reminiscent of the telomeric ends of linear eukaryal chromosomes and suggest that a primitive telomeric...

  3. Global diversity of marine isopods (except Asellota and crustacean symbionts.

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    Gary C B Poore

    Full Text Available The crustacean order Isopoda (excluding Asellota, crustacean symbionts and freshwater taxa comprise 3154 described marine species in 379 genera in 37 families according to the WoRMS catalogue. The history of taxonomic discovery over the last two centuries is reviewed. Although a well defined order with the Peracarida, their relationship to other orders is not yet resolved but systematics of the major subordinal taxa is relatively well understood. Isopods range in size from less than 1 mm to Bathynomus giganteus at 365 mm long. They inhabit all marine habitats down to 7280 m depth but with few doubtful exceptions species have restricted biogeographic and bathymetric ranges. Four feeding categories are recognised as much on the basis of anecdotal evidence as hard data: detritus feeders and browsers, carnivores, parasites, and filter feeders. Notable among these are the Cymothooidea that range from predators and scavengers to external blood-sucking micropredators and parasites. Isopods brood 10-1600 eggs depending on individual species. Strong sexual dimorphism is characteristic of several families, notably in Gnathiidae where sessile males live with a harem of females while juvenile praniza stages are ectoparasites of fish. Protandry is known in Cymothoidae and protogyny in Anthuroidea. Some Paranthuridae are neotenous. About half of all coastal, shelf and upper bathyal species have been recorded in the MEOW temperate realms, 40% in tropical regions and the remainder in polar seas. The greatest concentration of temperate species is in Australasia; more have been recorded from temperate North Pacific than the North Atlantic. Of tropical regions, the Central Indo-Pacific is home to more species any other region. Isopods are decidedly asymmetrical latitudinally with 1.35 times as many species in temperate Southern Hemisphere than the temperate North Atlantic and northern Pacific, and almost four times as many Antarctic as Arctic species. More species

  4. Exceptional diversity of Stefania (Anura, Cryptobatrachidae II: Six species from Mount Wokomung, Guyana

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    Ross D. MacCulloch

    2006-09-01

    Full Text Available Six species of Stefania were collected on Mount Wokomung, a tepui in the Pakaraima Mountains of Guyana. This unusually high diversity of Stefania is similar to that found on a neighbouring tepui, Mt. Ayanganna. The two tepuis support slightly different habitats. Conspecific Stefania from the two mountains differ somewhat in body size, toe disc size and colouration. Specimens from Mt. Wokomung are used to expand descriptions and distributions of some species.

  5. Deep sequencing reveals exceptional diversity and modes of transmission for bacterial sponge symbionts.

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    Webster, Nicole S; Taylor, Michael W; Behnam, Faris; Lücker, Sebastian; Rattei, Thomas; Whalan, Stephen; Horn, Matthias; Wagner, Michael

    2010-08-01

    Marine sponges contain complex bacterial communities of considerable ecological and biotechnological importance, with many of these organisms postulated to be specific to sponge hosts. Testing this hypothesis in light of the recent discovery of the rare microbial biosphere, we investigated three Australian sponges by massively parallel 16S rRNA gene tag pyrosequencing. Here we show bacterial diversity that is unparalleled in an invertebrate host, with more than 250,000 sponge-derived sequence tags being assigned to 23 bacterial phyla and revealing up to 2996 operational taxonomic units (95% sequence similarity) per sponge species. Of the 33 previously described 'sponge-specific' clusters that were detected in this study, 48% were found exclusively in adults and larvae - implying vertical transmission of these groups. The remaining taxa, including 'Poribacteria', were also found at very low abundance among the 135,000 tags retrieved from surrounding seawater. Thus, members of the rare seawater biosphere may serve as seed organisms for widely occurring symbiont populations in sponges and their host association might have evolved much more recently than previously thought. © 2009 Society for Applied Microbiology and Blackwell Publishing Ltd.

  6. The Late Devonian Gogo Formation Lägerstatte of Western Australia: Exceptional Early Vertebrate Preservation and Diversity

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    Long, John A.; Trinajstic, Kate

    2010-05-01

    The Gogo Formation of Western Australia preserves a unique Late Devonian (Frasnian) reef fauna. The exceptional three-dimensional preservation of macrofossils combined with unprecedented soft-tissue preservation (including muscle bundles, nerve cells, and umbilical structures) has yielded a particularly rich assemblage with almost 50 species of fishes described. The most significant discoveries have contributed to resolving placoderm phylogeny and elucidating their reproductive physiology. Specifically, these discoveries have produced data on the oldest known vertebrate embryos; the anatomy of the primitive actinopterygian neurocranium and phylogeny of the earliest actinopterygians; the histology, radiation, and plasticity of dipnoan (lungfish) dental and cranial structures; the anatomy and functional morphology of the extinct onychodonts; and the anatomy of the primitive tetrapodomorph head and pectoral fin.

  7. Educational assessment in Khyber Pakhtunkhwa Pakistan’s North-West Frontier Province: Practices, Issues, and Challenges for Educating Culturally Linguistically Diverse and Exceptional Children

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    Eirini Gouleta

    2015-11-01

    Full Text Available This article presents the case of Khyber Pakhtunkhwa (KP, Pakistan’s former North-West Frontier Province, and its provincial educational assessment policies and practices. These policies and practices affect millions of Culturally Linguistically Diverse and Exceptional (CLDE children who live in rural and remote areas, and areas afflicted by conflict and insurgency. The article raises questions about political interference, ethical conduct, and fairness in the administration and marking of the assessments. It discusses efforts for systematic administration and collection of learning assessment data, teacher professional development programs to improve assessment practices, policies which address the educational needs of the diverse students in the province, and challenges and barriers to province-wide sustainable education development. In conclusion, the author offers suggestions and recommendations for policy makers and education stakeholders towards capacity building and improvement of assessment practices for all learners while it attempts to shed light and dispel misconceptions about KP and its people.

  8. Exceptional phenomenology

    DEFF Research Database (Denmark)

    Aggerholm, Kenneth; Moltke Martiny, Kristian

    Phenomenological research is in traditional terms a matter of going 'back to the things themselves', as Husserl famously stated. But if phenomenology is to renew itself in creative ways and reveal new aspects of human experience it is of value to look for a certain kind of phenomena: exceptions. ...

  9. AMERICAN EXCEPTIONALISM

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    Oana-Andreea Pirnuta

    2017-11-01

    Full Text Available In an interconnected world where foreign relations matter not only for resources or military alliances but also for cultural relationships, it is highly important to have a better understanding of the power relations among nations. The information carries certain meanings that have important outcomes thus defining the power of a given nation. Foreign policy is the channel through which global politics is exercised. International politics is a hierarchy of power being determined by important cultural, economic as well as geographical aspects. The reasons and strategies that are used in order to reach the outcomes in global politics represent the focus of the present paper. The United States has been the leader in international politics since the early 20th century due to its vast resources and wealth as well as its cultural output. America’s interest in preserving a democratic and free world has its foundation in the beliefs and values it stands for the aim of this paper is to question whether or not there is a concrete premise for the idea of American exceptionalism.

  10. Diversity

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    Portraits In Courage Vol. VIII Portraits In Courage Vol. IX Portraits In Courage Vol. X AF Sites Social -Wide Initiative to Promote Diversity and Inclusion in the Federal Workforce Executive Order 13548 : Virtual Diversity Conference Air Force Diversity & Inclusion Air Force Diversity Graphic There is no

  11. Functional redundancy patterns reveal non-random assembly rules in a species-rich marine assemblage.

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    Nicolas Guillemot

    Full Text Available The relationship between species and the functional diversity of assemblages is fundamental in ecology because it contains key information on functional redundancy, and functionally redundant ecosystems are thought to be more resilient, resistant and stable. However, this relationship is poorly understood and undocumented for species-rich coastal marine ecosystems. Here, we used underwater visual censuses to examine the patterns of functional redundancy for one of the most diverse vertebrate assemblages, the coral reef fishes of New Caledonia, South Pacific. First, we found that the relationship between functional and species diversity displayed a non-asymptotic power-shaped curve, implying that rare functions and species mainly occur in highly diverse assemblages. Second, we showed that the distribution of species amongst possible functions was significantly different from a random distribution up to a threshold of ∼90 species/transect. Redundancy patterns for each function further revealed that some functions displayed fast rates of increase in redundancy at low species diversity, whereas others were only becoming redundant past a certain threshold. This suggested non-random assembly rules and the existence of some primordial functions that would need to be fulfilled in priority so that coral reef fish assemblages can gain a basic ecological structure. Last, we found little effect of habitat on the shape of the functional-species diversity relationship and on the redundancy of functions, although habitat is known to largely determine assemblage characteristics such as species composition, biomass, and abundance. Our study shows that low functional redundancy is characteristic of this highly diverse fish assemblage, and, therefore, that even species-rich ecosystems such as coral reefs may be vulnerable to the removal of a few keystone species.

  12. Colonic stem cell data are consistent with the immortal model of stem cell division under non-random strand segregation.

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    Walters, K

    2009-06-01

    Colonic stem cells are thought to reside towards the base of crypts of the colon, but their numbers and proliferation mechanisms are not well characterized. A defining property of stem cells is that they are able to divide asymmetrically, but it is not known whether they always divide asymmetrically (immortal model) or whether there are occasional symmetrical divisions (stochastic model). By measuring diversity of methylation patterns in colon crypt samples, a recent study found evidence in favour of the stochastic model, assuming random segregation of stem cell DNA strands during cell division. Here, the effect of preferential segregation of the template strand is considered to be consistent with the 'immortal strand hypothesis', and explore the effect on conclusions of previously published results. For a sample of crypts, it is shown how, under the immortal model, to calculate mean and variance of the number of unique methylation patterns allowing for non-random strand segregation and compare them with those observed. The calculated mean and variance are consistent with an immortal model that incorporates non-random strand segregation for a range of stem cell numbers and levels of preferential strand segregation. Allowing for preferential strand segregation considerably alters previously published conclusions relating to stem cell numbers and turnover mechanisms. Evidence in favour of the stochastic model may not be as strong as previously thought.

  13. Real-time definition of non-randomness in the distribution of genomic events.

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    Ulrich Abel

    Full Text Available Features such as mutations or structural characteristics can be non-randomly or non-uniformly distributed within a genome. So far, computer simulations were required for statistical inferences on the distribution of sequence motifs. Here, we show that these analyses are possible using an analytical, mathematical approach. For the assessment of non-randomness, our calculations only require information including genome size, number of (sampled sequence motifs and distance parameters. We have developed computer programs evaluating our analytical formulas for the real-time determination of expected values and p-values. This approach permits a flexible cluster definition that can be applied to most effectively identify non-random or non-uniform sequence motif distribution. As an example, we show the effectivity and reliability of our mathematical approach in clinical retroviral vector integration site distribution.

  14. An Approach to Distinguish between Plasticity and Non-random Distributions of Behavioral Types Along Urban Gradients in a Wild Passerine Bird

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    Philipp Sprau

    2017-08-01

    Full Text Available The impact of urbanization has been widely studied in the context of species diversity and life history evolution. Behavioral adaptation, by contrast, remains poorly understood because empirical studies rarely investigate the relative importance of two key mechanisms: plastic responses vs. non-random distributions of behavioral types. We propose here an approach that enables the simultaneous estimation of the respective roles of these distinct mechanisms. We investigated why risky behaviors are often associated with urbanization, using an urban nest box population of great tits (Parus major as a study system. We simultaneously and repeatedly quantified individual behavior (aggression and flight initiation distance as well as environmental factors characterizing level of urbanization (numbers of pedestrians, cars and cyclists. This enabled us to statistically distinguish plastic responses from patterns of non-random distributions of behavioral types. Data analyses revealed that individuals did not plastically adjust their behavior to the level of urbanization. Behavioral types were instead non-randomly distributed: bold birds occurred more frequently in areas with more cars and fewer pedestrians while shy individuals were predominantly found in areas with fewer cars and more pedestrians. These novel findings imply a major role for behavioral types in the evolutionary ecology of urban environments and call for the full integration of among- and within-individual variation in urban ecological studies.

  15. An Exceptional Memory

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    Hunter, Ian M. L.

    1977-01-01

    An account is given of the exceptional memory of the late Professor A. C. Aitken who was also a distinguished mathematician and mental calculator. Compared with Shereshevskii, another man with exceptional memory, he shows the scholar's reliance on conceptual mapping rather than the mnemonist's reliance on perceptual chaining. (Editor)

  16. MFTF exception handling system

    International Nuclear Information System (INIS)

    Nowell, D.M.; Bridgeman, G.D.

    1979-01-01

    In the design of large experimental control systems, a major concern is ensuring that operators are quickly alerted to emergency or other exceptional conditions and that they are provided with sufficient information to respond adequately. This paper describes how the MFTF exception handling system satisfies these requirements. Conceptually exceptions are divided into one of two classes. Those which affect command status by producing an abort or suspend condition and those which fall into a softer notification category of report only or operator acknowledgement requirement. Additionally, an operator may choose to accept an exception condition as operational, or turn off monitoring for sensors determined to be malfunctioning. Control panels and displays used in operator response to exceptions are described

  17. On exceptional instanton strings

    NARCIS (Netherlands)

    Del Zotto, M.; Lockhart, G.

    According to a recent classification of 6d (1, 0) theories within F-theory there are only six “pure” 6d gauge theories which have a UV superconformal fixed point. The corresponding gauge groups are SU(3), SO(8), F4, E6, E7, and E8. These exceptional models have BPS strings which are also instantons

  18. Nothing Exceptional: Against Agamben

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    Colatrella, Steven

    2011-01-01

    Giorgio Agamben's work has become widely influential as a guide to explaining the extra-constitutional powers assumed by governments under the rubric of the War on Terror. His formulations, such as Homo Sacer and State of Exception, have been extended to apply to a wide variety of experiences of repression of liberties or social control, including…

  19. Exceptionalism and globalism

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    John Cairns Jr

    2001-03-01

    Full Text Available ABSTRACT: Achieving sustainable use of the planet will require ethical judgments in both sciences and environmental politics. The purpose of this editorial is to discuss two paradigms, exceptionalism and globalism, that are important in this regard. Exceptionalism is the insistence that one set of rules or behaviors is acceptable for an individual or country but that a different set should be used for the rest of the world. For example, the disparity in per capita consumption of resources and economic status has increased dramatically in the last century, but the consumers of great amounts of resources do not feel a proportionate responsibility for addressing this issue. Globalism is defined as individual and societal willingness to diminish, postpone or forgo individual natural resource use to protect and enhance the integrity of the global ecological life support system. Increasing affluence and the still increasing human population, coupled with wide dissemination of information and an increasing awareness that humans occupy a finite planet, exacerbate this already difficult situation. Increased interest in sustainable use of the planet makes open discussion of these issues mandatory because individuals cannot function in isolation from the larger society of which they are a part. Similarly, no country can function in isolation from other countries, which collectively form an interactive mosaic. This discussion identifies some of the crucial issues related to exceptionalism and globalism, which must be addressed before sustainable use of the planet can be achieved.

  20. Correction of confounding bias in non-randomized studies by appropriate weighting.

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    Schmoor, Claudia; Gall, Christine; Stampf, Susanne; Graf, Erika

    2011-03-01

    In non-randomized studies, the assessment of a causal effect of treatment or exposure on outcome is hampered by possible confounding. Applying multiple regression models including the effects of treatment and covariates on outcome is the well-known classical approach to adjust for confounding. In recent years other approaches have been promoted. One of them is based on the propensity score and considers the effect of possible confounders on treatment as a relevant criterion for adjustment. Another proposal is based on using an instrumental variable. Here inference relies on a factor, the instrument, which affects treatment but is thought to be otherwise unrelated to outcome, so that it mimics randomization. Each of these approaches can basically be interpreted as a simple reweighting scheme, designed to address confounding. The procedures will be compared with respect to their fundamental properties, namely, which bias they aim to eliminate, which effect they aim to estimate, and which parameter is modelled. We will expand our overview of methods for analysis of non-randomized studies to methods for analysis of randomized controlled trials and show that analyses of both study types may target different effects and different parameters. The considerations will be illustrated using a breast cancer study with a so-called Comprehensive Cohort Study design, including a randomized controlled trial and a non-randomized study in the same patient population as sub-cohorts. This design offers ideal opportunities to discuss and illustrate the properties of the different approaches. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Non-random distribution of instability-associated chromosomal rearrangement breakpoints in human lymphoblastoid cells

    International Nuclear Information System (INIS)

    Moore, Stephen R.; Papworth, David; Grosovsky, Andrew J.

    2006-01-01

    Genomic instability is observed in tumors and in a large fraction of the progeny surviving irradiation. One of the best-characterized phenotypic manifestations of genomic instability is delayed chromosome aberrations. Our working hypothesis for the current study was that if genomic instability is in part attributable to cis mechanisms, we should observe a non-random distribution of chromosomes or sites involved in instability-associated rearrangements, regardless of radiation quality, dose, or trans factor expression. We report here the karyotypic examination of 296 instability-associated chromosomal rearrangement breaksites (IACRB) from 118 unstable TK6 human B lymphoblast, and isogenic derivative, clones. When we tested whether IACRB were distributed across the chromosomes based on target size, a significant non-random distribution was evident (p < 0.00001), and three IACRB hotspots (chromosomes 11, 12, and 22) and one IACRB coldspot (chromosome 2) were identified. Statistical analysis at the chromosomal band-level identified four IACRB hotspots accounting for 20% of all instability-associated breaks, two of which account for over 14% of all IACRB. Further, analysis of independent clones provided evidence within 14 individual clones of IACRB clustering at the chromosomal band level, suggesting a predisposition for further breaks after an initial break at some chromosomal bands. All of these events, independently, or when taken together, were highly unlikely to have occurred by chance (p < 0.000001). These IACRB band-level cluster hotspots were observed independent of radiation quality, dose, or cellular p53 status. The non-random distribution of instability-associated chromosomal rearrangements described here significantly differs from the distribution that was observed in a first-division post-irradiation metaphase analysis (p = 0.0004). Taken together, these results suggest that genomic instability may be in part driven by chromosomal cis mechanisms

  2. X exceptionalism in Caenorhabditis speciation.

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    Cutter, Asher D

    2017-11-13

    Speciation genetics research in diverse organisms shows the X-chromosome to be exceptional in how it contributes to "rules" of speciation. Until recently, however, the nematode phylum has been nearly silent on this issue, despite the model organism Caenorhabditis elegans having touched most other topics in biology. Studies of speciation with Caenorhabditis accelerated with the recent discovery of species pairs showing partial interfertility. The resulting genetic analyses of reproductive isolation in nematodes demonstrate key roles for the X-chromosome in hybrid male sterility and inviability, opening up new understanding of the genetic causes of Haldane's rule, Darwin's corollary to Haldane's rule, and enabling tests of the large-X effect hypothesis. Studies to date implicate improper chromatin regulation of the X-chromosome by small RNA pathways as integral to hybrid male dysfunction. Sexual transitions in reproductive mode to self-fertilizing hermaphroditism inject distinctive molecular evolutionary features into the speciation process for some species. Caenorhabditis also provides unique opportunities for analysis in a system with XO sex determination that lacks a Y-chromosome, sex chromosome-dependent sperm competition differences and mechanisms of gametic isolation, exceptional accessibility to the development process and rapid experimental evolution. As genetic analysis of reproductive isolation matures with investigation of multiple pairs of Caenorhabditis species and new species discovery, nematodes will provide a powerful complement to more established study organisms for deciphering the genetic basis of and rules to speciation. © 2017 John Wiley & Sons Ltd.

  3. Is India the Exception?

    DEFF Research Database (Denmark)

    Nielsen, Klaus; Storm, Rasmus K.

    2013-01-01

    in international sport events a similar impact of extraordinary growth rates has been almost totally absent in the case of India. Is India an exception? Several econometric studies have shown that income per capita is a significant variable explaining elite sport results such as results in the Olympic Games. From...... in the sports of the Olympic Summer Games. The findings show only a very weak correlation, if any at all. However, a detailed analysis of country evidence shows interesting trends and details. The paper concludes with tentative explanations for the findings including the contradictory country evidence....

  4. Large-area imaging reveals biologically driven non-random spatial patterns of corals at a remote reef

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    Edwards, Clinton B.; Eynaud, Yoan; Williams, Gareth J.; Pedersen, Nicole E.; Zgliczynski, Brian J.; Gleason, Arthur C. R.; Smith, Jennifer E.; Sandin, Stuart A.

    2017-12-01

    For sessile organisms such as reef-building corals, differences in the degree of dispersion of individuals across a landscape may result from important differences in life-history strategies or may reflect patterns of habitat availability. Descriptions of spatial patterns can thus be useful not only for the identification of key biological and physical mechanisms structuring an ecosystem, but also by providing the data necessary to generate and test ecological theory. Here, we used an in situ imaging technique to create large-area photomosaics of 16 plots at Palmyra Atoll, central Pacific, each covering 100 m2 of benthic habitat. We mapped the location of 44,008 coral colonies and identified each to the lowest taxonomic level possible. Using metrics of spatial dispersion, we tested for departures from spatial randomness. We also used targeted model fitting to explore candidate processes leading to differences in spatial patterns among taxa. Most taxa were clustered and the degree of clustering varied by taxon. A small number of taxa did not significantly depart from randomness and none revealed evidence of spatial uniformity. Importantly, taxa that readily fragment or tolerate stress through partial mortality were more clustered. With little exception, clustering patterns were consistent with models of fragmentation and dispersal limitation. In some taxa, dispersion was linearly related to abundance, suggesting density dependence of spatial patterning. The spatial patterns of stony corals are non-random and reflect fundamental life-history characteristics of the taxa, suggesting that the reef landscape may, in many cases, have important elements of spatial predictability.

  5. Is India the Exception?

    DEFF Research Database (Denmark)

    Nielsen, Klaus; Storm, Rasmus K.

    India is still the extreme under-achiever in international sport competitions. Whereas in China high growth rates have been accompanied by a huge improvement in its ranking in international sport events a similar impact of extraordinary growth rates is seemingly totally absent in the case of India....... Is India an exception? Several econometric studies have shown that income per capita is a significant variable explaining elite sport results such as results in the Olympic Games. From this stylized fact follows the hypothesis that 'above/below average' growth rates lead to relative improvements...... between growth in GNP per capita and growth in medal points (no. 1: five points, no. 2: three points, no.3: two points) in Olympic Summer Games. The findings show no correlation and in a few calculations a very weak correlation. Among the countries behaving in accordance with the hypothesis in the most...

  6. Non-random intrachromosomal distribution of radiation-induced chromatid aberrations in Vicia faba. [Aberration clustering

    Energy Technology Data Exchange (ETDEWEB)

    Schubert, I; Rieger, R [Akademie der Wissenschaften der DDR, Gatersleben. Zentralinst. fuer Genetik und Kulturpflanzenforschung

    1976-04-01

    A reconstructed karyotype of Vicia faba, with all chromosomes individually distinguishable, was treated with X-rays, fast neutrons, (/sup 3/H) uridine (/sup 3/HU). The distribution within metaphase chromosomes of induced chromatid aberrations was non-random for all agents used. Aberration clustering, in part agent specific, occurred in chromosome segments containing heterochromatin as defined by the presence of G bands. The pattern of aberration clustering found after treatment with /sup 3/HU did not allow the recognition of chromosome regions active in transcription during treatment. Furthermore, it was impossible to obtain unambiguous indications of the presence of AT- and GC-base clusters from the patterns of /sup 3/HT- and /sup 3/HC-induced chromatid aberrations, respectively. Possible reasons underlying these observations are discussed.

  7. Exceptional composite dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Ballesteros, Guillermo [Universite Paris Saclay, CEA, CNRS, Institut de Physique Theorique, Gif-sur-Yvette (France); Carmona, Adrian [CERN, Theoretical Physics Department, Geneva (Switzerland); Chala, Mikael [Universitat de Valencia y IFIC, Universitat de Valencia-CSIC, Departament de Fisica Teorica, Burjassot, Valencia (Spain)

    2017-07-15

    We study the dark matter phenomenology of non-minimal composite Higgs models with SO(7) broken to the exceptional group G{sub 2}. In addition to the Higgs, three pseudo-Nambu-Goldstone bosons arise, one of which is electrically neutral. A parity symmetry is enough to ensure this resonance is stable. In fact, if the breaking of the Goldstone symmetry is driven by the fermion sector, this Z{sub 2} symmetry is automatically unbroken in the electroweak phase. In this case, the relic density, as well as the expected indirect, direct and collider signals are then uniquely determined by the value of the compositeness scale, f. Current experimental bounds allow one to account for a large fraction of the dark matter of the Universe if the dark matter particle is part of an electroweak triplet. The totality of the relic abundance can be accommodated if instead this particle is a composite singlet. In both cases, the scale f and the dark matter mass are of the order of a few TeV. (orig.)

  8. New Nordic Exceptionalism

    DEFF Research Database (Denmark)

    Danbolt, Mathias

    2016-01-01

    At the 2009 Nordic Culture Forum summit in Berlin that centered on the profiling and branding of the Nordic region in a globalized world, one presenter stood out from the crowd. The lobbyist Annika Sigurdardottir delivered a speech that called for the establishment of “The United Nations of Norden...... that have been central to the debates on the branding of Nordicity over the last decades: on the one hand, the discourse of “Nordic exceptionalism,” that since the 1960s has been central to the promotion of a Nordic political, socio-economic, and internationalist “third way” model, and, on the other hand......, the discourse on the “New Nordic,” that emerged out of the New Nordic Food-movement in the early 2000s, and which has given art and culture a privileged role in the international re-fashioning of the Nordic brand. Through an analysis of Kim and Einhorn’s United Nations of Norden (UNN)-performance, the article...

  9. Non-random alkylation of DNA sequences induced in vivo by chemical mutagens

    Energy Technology Data Exchange (ETDEWEB)

    Durante, M.; Geri, C.; Bonatti, S.; Parenti, R. (Universita di Pisa (Italy))

    1989-08-01

    Previous studies of the interaction of alkylating agents on the eukaryotic genome support the idea that induction of DNA adducts is at specific genomic sites. Here we show molecular and cytological evidence that alkylation is rather specific. Mammalian cell cultures were exposed to different doses of mutagens and the DNA was analyzed by density gradient ultracentrifugation, hydroxylapatite fractionation, and by restriction enzyme analysis. Studies with the labelled mutagens N-ethyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine show that there is a non-random distribution of the adducts. The adducts are found more frequently in A-T, G-C rich satellite DNA and highly repetitive sequences. Analysis with restriction enzymes shows that both methyl and ethyl groups influence the restriction patterns of the enzymes HpaII and MspI that recognize specific endogenous DNA methylation. These data suggest, as a subsequent mechanism, a modification in the pattern of the normal endogenous methylation of 5-methylcytosine.

  10. Random and non-random mating populations: Evolutionary dynamics in meiotic drive.

    Science.gov (United States)

    Sarkar, Bijan

    2016-01-01

    Game theoretic tools are utilized to analyze a one-locus continuous selection model of sex-specific meiotic drive by considering nonequivalence of the viabilities of reciprocal heterozygotes that might be noticed at an imprinted locus. The model draws attention to the role of viability selections of different types to examine the stable nature of polymorphic equilibrium. A bridge between population genetics and evolutionary game theory has been built up by applying the concept of the Fundamental Theorem of Natural Selection. In addition to pointing out the influences of male and female segregation ratios on selection, configuration structure reveals some noted results, e.g., Hardy-Weinberg frequencies hold in replicator dynamics, occurrence of faster evolution at the maximized variance fitness, existence of mixed Evolutionarily Stable Strategy (ESS) in asymmetric games, the tending evolution to follow not only a 1:1 sex ratio but also a 1:1 different alleles ratio at particular gene locus. Through construction of replicator dynamics in the group selection framework, our selection model introduces a redefining bases of game theory to incorporate non-random mating where a mating parameter associated with population structure is dependent on the social structure. Also, the model exposes the fact that the number of polymorphic equilibria will depend on the algebraic expression of population structure. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner

    Science.gov (United States)

    Kondrashov, F. A.; Toshchakov, S. V.; Dominova, I.; Shvyreva, U. S.; Vrublevskaya, V. V.; Morenkov, O. S.; Panyukov, V. V.

    2017-01-01

    Dps is a multifunctional homododecameric protein that oxidizes Fe2+ ions accumulating them in the form of Fe2O3 within its protein cavity, interacts with DNA tightly condensing bacterial nucleoid upon starvation and performs some other functions. During the last two decades from discovery of this protein, its ferroxidase activity became rather well studied, but the mechanism of Dps interaction with DNA still remains enigmatic. The crucial role of lysine residues in the unstructured N-terminal tails led to the conventional point of view that Dps binds DNA without sequence or structural specificity. However, deletion of dps changed the profile of proteins in starved cells, SELEX screen revealed genomic regions preferentially bound in vitro and certain affinity of Dps for artificial branched molecules was detected by atomic force microscopy. Here we report a non-random distribution of Dps binding sites across the bacterial chromosome in exponentially growing cells and show their enrichment with inverted repeats prone to form secondary structures. We found that the Dps-bound regions overlap with sites occupied by other nucleoid proteins, and contain overrepresented motifs typical for their consensus sequences. Of the two types of genomic domains with extensive protein occupancy, which can be highly expressed or transcriptionally silent only those that are enriched with RNA polymerase molecules were preferentially occupied by Dps. In the dps-null mutant we, therefore, observed a differentially altered expression of several targeted genes and found suppressed transcription from the dps promoter. In most cases this can be explained by the relieved interference with Dps for nucleoid proteins exploiting sequence-specific modes of DNA binding. Thus, protecting bacterial cells from different stresses during exponential growth, Dps can modulate transcriptional integrity of the bacterial chromosome hampering RNA biosynthesis from some genes via competition with RNA polymerase

  12. Improving Sleep for Hospitalized Antepartum Patients: A Non-Randomized Controlled Pilot Study.

    Science.gov (United States)

    Lee, Kathryn A; Gay, Caryl L

    2017-12-15

    To evaluate feasibility and efficacy of a hospital-based protocol for improving sleep in high- risk antepartum patients. Sleep measures were compared during 1 week of hospitalization before and after implementing a Sleep Improvement Protocol for Antepartum Patients (SIP-AP). A non-randomized convenience sample of usual care controls was compared to a subsequent intervention sample after the protocol was implemented. Women were eligible if they spoke English, were medically stable, pregnant for at least 20 weeks, and hospitalized at least 24 hours; 25 pregnant women had sufficient data for analyses (11 controls, 14 intervention). Sleep was assessed in 3 ways: the Pittsburgh Sleep Quality Index was completed after obtaining consent to estimate sleep quality prior to hospital admission; sleep diary completed each hospital day; and General Sleep Disturbance Scale completed at 7 days or prior to hospital discharge. Symptoms that could affect sleep were assessed with the Memorial Symptom Assessment Scale. Both groups recorded similar sleep duration (7 hours) but the intervention group had fewer symptoms and significantly ( P = .015) lower sleep disturbance scores (53.1 ± 14.5) than controls (71.9 ± 18.8). Participant feedback about the intervention was positive, although adherence to components of the intervention protocol was variable. This pilot study provides evidence of the feasibility and preliminary efficacy of the SIP-AP intervention for reducing symptoms and improving sleep of antepartum patients during hospitalization. Further detailed evaluation of specific components of this protocol is warranted, and other types of hospitalized patients may benefit from unit-based modifications to this SIP-AP protocol. © 2017 American Academy of Sleep Medicine

  13. A Non-randomized Controlled Trial of EMDR on Affective Symptoms in Patients With Glioblastoma Multiforme

    Directory of Open Access Journals (Sweden)

    Monika Szpringer

    2018-05-01

    Full Text Available Glioblastoma multiforme (GBM is a highly aggressive brain cancer and its survival after diagnosis is less than 2 years. Therefore, GBM patients are especially prone to co-occurring psychological conditions such as anxiety and depressive disorders. Furthermore, aggressive medical therapies affect patients’ lives, undermining their sense of meaning and coherence. The main aim of this study was to determine the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR therapy on anxiety, depression and sense of coherence in patients with GBM. Thirty-seven GBM-diagnosed women were included in this trial and received standard medical care. Of those, 18 patients were treated during 4 months with 10–12 individual EMDR sessions (60–90 minutes each. Nineteen GBM patients were used as a non-randomized control group as they consented to psychological evaluations but not to a psychotherapeutic intervention. The groups were homogeneous in terms of gender, age, educational level and treatment, but not in anxiety and depressive levels at baseline. All patients were evaluated at baseline, after treatment (4 months and at follow-up (further 4 months by the Hospital Anxiety and Depression Scale (HADS-M and the Sense of Coherence Scale (SOC-29. Caregivers in both groups were interviewed by the Patient Caregiver Questionnaire after 4 months follow-up. Statistical analyses were conducted using ANOVA statistics, correlation and regression analysis. Results showed a statistically significant decrease in the EMDR group in anxiety, depression and anger, when compared to the experimental group. EMDR therapy also had a positive impact upon the sense of coherence level in the experimental group, whereas in the control group this declined. Finally, the caregivers reported beneficial outcomes of the EMDR therapy with less anxiety- and anger-related behaviors in patients in the experimental group compared to the control group. This study is the first to show

  14. Trends in Modern Exception Handling

    Directory of Open Access Journals (Sweden)

    Marcin Kuta

    2003-01-01

    Full Text Available Exception handling is nowadays a necessary component of error proof information systems. The paper presents overview of techniques and models of exception handling, problems connected with them and potential solutions. The aspects of implementation of propagation mechanisms and exception handling, their effect on semantics and general program efficiency are also taken into account. Presented mechanisms were adopted to modern programming languages. Considering design area, formal methods and formal verification of program properties we can notice exception handling mechanisms are weakly present what makes a field for future research.

  15. Multidisciplinary intervention reducing readmissions in medical inpatients: a prospective, non-randomized study

    Directory of Open Access Journals (Sweden)

    Torisson G

    2013-09-01

    Full Text Available Gustav Torisson,1 Lennart Minthon,1 Lars Stavenow,2 Elisabet Londos1 1Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, 2Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden Background: The purpose of this study was to examine whether a multidisciplinary intervention targeting drug-related problems, cognitive impairment, and discharge miscommunication could reduce readmissions in a general hospital population. Methods: This prospective, non-randomized intervention study was carried out at the department of general internal medicine at a tertiary university hospital. Two hundred medical inpatients living in the community and aged over 60 years were included. Ninety-nine patients received interventions and 101 received standard care. Control/intervention allocation was determined by geographic selection. Interventions consisted of a comprehensive medication review, improved discharge planning, post-discharge telephone follow-up, and liaison with the patient's general practitioner. The main outcome measures recorded were readmissions and hospital nights 12 months after discharge. Separate analyses were made for 12-month survivors and from an intention-to-treat perspective. Comparative analyses were made between groups as well as within groups over time. Results: After 12 months, survivors in the control group had 125 readmissions in total, compared with 58 in the intervention group (Mann–Whitney U test, P = 0.02. For hospital nights, the numbers were 1,228 and 492, respectively (P = 0.009. Yearly admissions had increased from the previous year in the control group from 77 to 125 (Wilcoxon signed-rank test, P = 0.002 and decreased from 75 to 58 in the intervention group (P = 0.25. From the intention-to-treat perspective, the same general pattern was observed but was not significant (1,827 versus 1,008 hospital nights, Mann–Whitney test, P = 0.054. Conclusion: A multidisciplinary approach

  16. An Exceptional Adenocarcinoma in a Girl

    Directory of Open Access Journals (Sweden)

    Bangaly Traore

    2018-01-01

    Full Text Available Anal adenocarcinoma is very rare and usually occurs in the elderly. We present a case of a 12-year-old girl with an anal margin painful tumor infiltrating the lower rectum, with perineal and vulvar permeation nodules and bilateral fixed inguinal and iliac lymph nodes. Histology showed anal adenocarcinoma with mucosecreting component and independent cells. She had no extra pelvic metastasis on CT scan. She underwent a colostomy and palliative care. This exceptional case challenges us on the diversity of forms of anal cancers that require a multidisciplinary approach. The precarious social context and the age of onset make it difficult to manage this rare cancer.

  17. Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates.

    Science.gov (United States)

    Werner, Benjamin; Sottoriva, Andrea

    2018-06-01

    The immortal strand hypothesis poses that stem cells could produce differentiated progeny while conserving the original template strand, thus avoiding accumulating somatic mutations. However, quantitating the extent of non-random DNA strand segregation in human stem cells remains difficult in vivo. Here we show that the change of the mean and variance of the mutational burden with age in healthy human tissues allows estimating strand segregation probabilities and somatic mutation rates. We analysed deep sequencing data from healthy human colon, small intestine, liver, skin and brain. We found highly effective non-random DNA strand segregation in all adult tissues (mean strand segregation probability: 0.98, standard error bounds (0.97,0.99)). In contrast, non-random strand segregation efficiency is reduced to 0.87 (0.78,0.88) in neural tissue during early development, suggesting stem cell pool expansions due to symmetric self-renewal. Healthy somatic mutation rates differed across tissue types, ranging from 3.5 × 10-9/bp/division in small intestine to 1.6 × 10-7/bp/division in skin.

  18. Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates.

    Directory of Open Access Journals (Sweden)

    Benjamin Werner

    2018-06-01

    Full Text Available The immortal strand hypothesis poses that stem cells could produce differentiated progeny while conserving the original template strand, thus avoiding accumulating somatic mutations. However, quantitating the extent of non-random DNA strand segregation in human stem cells remains difficult in vivo. Here we show that the change of the mean and variance of the mutational burden with age in healthy human tissues allows estimating strand segregation probabilities and somatic mutation rates. We analysed deep sequencing data from healthy human colon, small intestine, liver, skin and brain. We found highly effective non-random DNA strand segregation in all adult tissues (mean strand segregation probability: 0.98, standard error bounds (0.97,0.99. In contrast, non-random strand segregation efficiency is reduced to 0.87 (0.78,0.88 in neural tissue during early development, suggesting stem cell pool expansions due to symmetric self-renewal. Healthy somatic mutation rates differed across tissue types, ranging from 3.5 × 10-9/bp/division in small intestine to 1.6 × 10-7/bp/division in skin.

  19. Home based telemedicine intervention for patients with uncontrolled hypertension: - a real life - non-randomized study

    Science.gov (United States)

    2014-01-01

    Background Control of blood pressure is frequently inadequate in spite of availability of several classes of well tolerated and effective antihypertensive drugs. Several factors, including the use of suboptimal doses of drugs, inadequate or ineffective treatments and poor drug compliance may be the reason for this phenomenon. The aim of the current non- randomized study was to evaluate the effectiveness of a Home-Based Telemedicine service in patients with uncontrolled hypertension. Methods 74 patients were enrolled in a Home Based Telemedicine group and 94 patients in the Usual Care group. At baseline and at the end of the study, patients in both groups were seen in a cardiology office. Patients in Home Based Telemedicine group additionally were followed by a physician-nurse, through scheduled and unscheduled telephone appointments. These patients also received a blood pressure measuring device that could transmit the readings to a central data monitor via secure data connection. Results During the study period (80 ± 25 days), a total of 17401 blood pressure measurements were taken in the Home Based Telemedicine group corresponding to 236 ± 136 readings per patient and a mean daily measurement of 3 ± 1.7. The scheduled telephone contacts (initiated by the nurse) equaled to 5.2 ± 4.3/patient (370 in total) and the unscheduled telephone contacts (initiated by the patients) were 0.4 ± 0.9/patient (30 in total). The mean systolic blood pressure values decreased from 153 ± 19 mmHg to 130 ± 15 mmHg (p < 0.0001) at the end of the study and diastolic blood pressure values decreased from 89 ± 10 mmHg to 76 ± 11 mmHg (p < 0.0001). In the Usual Care group, the mean systolic blood pressure values decreased from 156 ± 16 mmHg to 149 ± 17 mmHg (p < 0.05) at the end of the study and diastolic blood pressure values decreased from 90 ± 8 mmHg to 86 ± 9 mmHg (p < 0.05). The changes in drug

  20. Exceptional groups from open strings

    International Nuclear Information System (INIS)

    Gaberdiel, M.R.; Zwiebach, B.

    1998-01-01

    We consider type IIB theory compactified on a two-sphere in the presence of mutually non-local 7-branes. The BPS states associated with the gauge vectors of exceptional groups are seen to arise from open strings connecting the 7-branes, and multi-pronged open strings capable of ending on more than two 7-branes. These multi-pronged strings are built from open string junctions that arise naturally when strings cross 7-branes. The different string configurations can be multiplied as traditional open strings, and are shown to generate the structure of exceptional groups. (orig.)

  1. Learned Helplessness in Exceptional Children.

    Science.gov (United States)

    Brock, Herman B.; Kowitz, Gerald T.

    The research literature on learned helplessness in exceptional children is reviewed and the authors' efforts to identify and retrain learning disabled (LD) children who have characteristics typical of learned helplessness are reported. Twenty-eight elementary aged LD children viewed as "learned helpless" were randomly assigned to one of four…

  2. 76 FR 53157 - Excepted Service

    Science.gov (United States)

    2011-08-25

    ... OFFICE OF PERSONNEL MANAGEMENT Excepted Service AGENCY: U.S. Office of Personnel Management (OPM... Administration. Office of Management. Special Assistant.... DE110117 6/22/2011 Office of the Special Assistant... Directors... Special Assistant.... EB110010 6/9/2011 GENERAL SERVICES ADMINISTRATION... Pacific Rim Region...

  3. Exceptional Responders Initial Feasibility Results

    Science.gov (United States)

    A pilot study evaluating identification of cancer patients who respond to treatment that is ineffective in at least 90 percent of patients found that it was indeed able to confirm a majority of proposed patients as exceptional responders based on clinical

  4. Exceptional and Spinorial Conformal Windows

    DEFF Research Database (Denmark)

    Mojaza, Matin; Pica, Claudio; Ryttov, Thomas

    2012-01-01

    We study the conformal window of gauge theories containing fermionic matter fields, where the gauge group is any of the exceptional groups with the fermions transforming according to the fundamental and adjoint representations and the orthogonal groups where the fermions transform according...

  5. Microstructural descriptors and cellular automata simulation of the effects of non-random nuclei location on recrystallization in two dimensions

    Directory of Open Access Journals (Sweden)

    Paulo Rangel Rios

    2006-06-01

    Full Text Available The effect of non-random nuclei location and the efficiency of microstructural descriptors in assessing such a situation are studied. Cellular automata simulation of recrystallization in two dimensions is carried out to simulate microstrutural evolution for nuclei distribution ranging from a periodic arrangement to clusters of nuclei. The simulation results are compared in detail with microstrutural descriptors normally used to follow transformation evolution. It is shown that the contiguity is particularly relevant to detect microstructural deviations from randomness. This work focuses on recrystallization but its results are applicable to any nucleation and growth transformation.

  6. Non-Random Variability in Functional Composition of Coral Reef Fish Communities along an Environmental Gradient.

    Science.gov (United States)

    Plass-Johnson, Jeremiah G; Taylor, Marc H; Husain, Aidah A A; Teichberg, Mirta C; Ferse, Sebastian C A

    2016-01-01

    Changes in the coral reef complex can affect predator-prey relationships, resource availability and niche utilisation in the associated fish community, which may be reflected in decreased stability of the functional traits present in a community. This is because particular traits may be favoured by a changing environment, or by habitat degradation. Furthermore, other traits can be selected against because degradation can relax the association between fishes and benthic habitat. We characterised six important ecological traits for fish species occurring at seven sites across a disturbed coral reef archipelago in Indonesia, where reefs have been exposed to eutrophication and destructive fishing practices for decades. Functional diversity was assessed using two complementary indices (FRic and RaoQ) and correlated to important environmental factors (live coral cover and rugosity, representing local reef health, and distance from shore, representing a cross-shelf environmental gradient). Indices were examined for both a change in their mean, as well as temporal (short-term; hours) and spatial (cross-shelf) variability, to assess whether fish-habitat association became relaxed along with habitat degradation. Furthermore, variability in individual traits was examined to identify the traits that are most affected by habitat change. Increases in the general reef health indicators, live coral cover and rugosity (correlated with distance from the mainland), were associated with decreases in the variability of functional diversity and with community-level changes in the abundance of several traits (notably home range size, maximum length, microalgae, detritus and small invertebrate feeding and reproductive turnover). A decrease in coral cover increased variability of RaoQ while rugosity and distance both inversely affected variability of FRic; however, averages for these indices did not reveal patterns associated with the environment. These results suggest that increased

  7. Discovering non-random segregation of sister chromatids: The naïve treatment of a premature discovery

    Directory of Open Access Journals (Sweden)

    Karl G. Lark

    2013-02-01

    Full Text Available The discovery of non-random chromosome segregation is discussed from the perspective of what was known in1965 and1966. The distinction between daughter, parent or grandparent strands of DNA was developed in a bacterial system and led to the discovery that multiple copies of DNA elements of bacteria are not distributed randomly with respect to the age of the template strand. Experiments with higher eukaryotic cells demonstrated that during mitosis Mendel’s laws were violated; and the initial serendipitous choice of eukaryotic cell system led to the striking example of non-random segregation of parent and grand-parent DNA template strands in primary cultures of cells derived from mouse embryos. Attempts to extrapolate these findings to established TC lines demonstrated that the property could be lost. Experiments using plant root tips demonstrated that the phenomenon exists in plants and that it was, at some level, under genetic control. Despite publication in major journals and symposia (Lark et al. (1966a; Lark (1967a; 1967b; 1969, 1969a; 1969b the potential implications of these findings were ignored for several decades. Here we explore possible reasons for the pre-maturity (Stent, 1972 of this discovery.

  8. Network meta-analysis incorporating randomized controlled trials and non-randomized comparative cohort studies for assessing the safety and effectiveness of medical treatments: challenges and opportunities

    OpenAIRE

    Cameron, Chris; Fireman, Bruce; Hutton, Brian; Clifford, Tammy; Coyle, Doug; Wells, George; Dormuth, Colin R.; Platt, Robert; Toh, Sengwee

    2015-01-01

    Network meta-analysis is increasingly used to allow comparison of multiple treatment alternatives simultaneously, some of which may not have been compared directly in primary research studies. The majority of network meta-analyses published to date have incorporated data from randomized controlled trials (RCTs) only; however, inclusion of non-randomized studies may sometimes be considered. Non-randomized studies can complement RCTs or address some of their limitations, such as short follow-up...

  9. CMS : An exceptional load for an exceptional work site

    CERN Multimedia

    2001-01-01

    Components of the CMS vacuum tank have been delivered to the detector assembly site at Cessy. The complete inner shell was delivered to CERN by special convoy while the outer shell is being assembled in situ. The convoy transporting the inner shell of the CMS vacuum tank took a week to cover the distance between Lons-le-Saunier and Point 5 at Cessy. Left: the convoy making its way down from the Col de la Faucille. With lights flashing, flanked by police outriders and with roads temporarily closed, the exceptional load that passed through the Pays de Gex on Monday 20 May was accorded the same VIP treatment as a leading state dignitary. But this time it was not the identity of the passenger but the exceptional size of the object being transported that made such arrangements necessary. A convoy of two lorries was needed to transport the load, an enormous 13-metre long, 6 metre diameter cylinder weighing 120 tonnes. It took a week to cover the 120 kilometres between Lons-le-Saunier and the assembly site for...

  10. Exceptional circles of radial potentials

    International Nuclear Information System (INIS)

    Music, M; Perry, P; Siltanen, S

    2013-01-01

    A nonlinear scattering transform is studied for the two-dimensional Schrödinger equation at zero energy with a radial potential. Explicit examples are presented, both theoretically and computationally, of potentials with nontrivial singularities in the scattering transform. The singularities arise from non-uniqueness of the complex geometric optics solutions that define the scattering transform. The values of the complex spectral parameter at which the singularities appear are called exceptional points. The singularity formation is closely related to the fact that potentials of conductivity type are ‘critical’ in the sense of Murata. (paper)

  11. Non-random temporary emigration and the robust design: Conditions for bias at the end of a time series: Section VIII

    Science.gov (United States)

    Langtimm, Catherine A.

    2008-01-01

    Deviations from model assumptions in the application of capture–recapture models to real life situations can introduce unknown bias. Understanding the type and magnitude of bias under these conditions is important to interpreting model results. In a robust design analysis of long-term photo-documented sighting histories of the endangered Florida manatee, I found high survival rates, high rates of non-random temporary emigration, significant time-dependence, and a diversity of factors affecting temporary emigration that made it difficult to model emigration in any meaningful fashion. Examination of the time-dependent survival estimates indicated a suspicious drop in survival rates near the end of the time series that persisted when the original capture histories were truncated and reanalyzed under a shorter time frame. Given the wide swings in manatee emigration estimates from year to year, a likely source of bias in survival was the convention to resolve confounding of the last survival probability in a time-dependent model with the last emigration probabilities by setting the last unmeasurable emigration probability equal to the previous year’s probability when the equality was actually false. Results of a series of simulations demonstrated that if the unmeasurable temporary emigration probabilities in the last time period were not accurately modeled, an estimation model with significant annual variation in survival probabilities and emigration probabilities produced bias in survival estimates at the end of the study or time series being explored. Furthermore, the bias propagated back in time beyond the last two time periods and the number of years affected varied positively with survival and emigration probabilities. Truncating the data to a shorter time frame and reanalyzing demonstrated that with additional years of data surviving temporary emigrants eventually return and are detected, thus in subsequent analysis unbiased estimates are eventually realized.

  12. Sucralfate gel as a radioprotector against radiation induced dermatitis in a hypo-fractionated schedule: a non-randomized study.

    Science.gov (United States)

    Kouloulias, V; Asimakopoulos, C; Tolia, M; Filippou, G; Platoni, K; Dilvoi, M; Beli, I; Georgakopoulos, J; Patatoukas, G; Kelekis, N

    2013-04-01

    External beam radiotherapy with high doses provokes many acute skin reactions, such as erythema and moist desquamation. Many topical preparations are used in radiation oncology departments in the skin care. Sucralfate humid gel, a colloidal physical form of the anti-ulcer drug sucralfate, promotes epithelial regeneration and activates cell proliferation. Based on this knowledge, we performed a non-randomized clinical trial to evaluate the efficacy of topical sucralfate gel in 30 breast cancer patients receiving postoperative accelerated hypofractionated photon beam therapy. The comparison was performed with 30 patients as historical controls. The acute reaction of the skin was significantly lower in the group receiving the sucralfate gel (p<0.05, Mann Whitney test), while 90% of the patients had no evidence of radiation induced skin toxicity. There was no sucralfate gel related toxicity reported by any patient in this study. More patients in a randomized way are needed for more definite results.

  13. The physics of exceptional points

    International Nuclear Information System (INIS)

    Heiss, W D

    2012-01-01

    A short résumé is given about the nature of exceptional points (EPs) followed by discussions about their ubiquitous occurrence in a great variety of physical problems. EPs feature in classical as well as in quantum mechanical problems. They are associated with symmetry breaking for PT-symmetric Hamiltonians, where a great number of experiments has been performed, in particular in optics, and to an increasing extent in atomic and molecular physics. EPs are involved in quantum phase transition and quantum chaos; they produce dramatic effects in multichannel scattering, specific time dependence and more. In nuclear physics, they are associated with instabilities and continuum problems. Being spectral singularities they also affect approximation schemes. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Quantum physics with non-Hermitian operators’. (paper)

  14. 42 CFR 423.578 - Exceptions process.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Exceptions process. 423.578 Section 423.578 Public..., Redeterminations, and Reconsiderations § 423.578 Exceptions process. (a) Requests for exceptions to a plan's tiered... sponsor may design its exception process so that very high cost or unique drugs are not eligible for a...

  15. Tree phylogenetic diversity promotes host-parasitoid interactions.

    Science.gov (United States)

    Staab, Michael; Bruelheide, Helge; Durka, Walter; Michalski, Stefan; Purschke, Oliver; Zhu, Chao-Dong; Klein, Alexandra-Maria

    2016-07-13

    Evidence from grassland experiments suggests that a plant community's phylogenetic diversity (PD) is a strong predictor of ecosystem processes, even stronger than species richness per se This has, however, never been extended to species-rich forests and host-parasitoid interactions. We used cavity-nesting Hymenoptera and their parasitoids collected in a subtropical forest as a model system to test whether hosts, parasitoids, and their interactions are influenced by tree PD and a comprehensive set of environmental variables, including tree species richness. Parasitism rate and parasitoid abundance were positively correlated with tree PD. All variables describing parasitoids decreased with elevation, and were, except parasitism rate, dependent on host abundance. Quantitative descriptors of host-parasitoid networks were independent of the environment. Our study indicates that host-parasitoid interactions in species-rich forests are related to the PD of the tree community, which influences parasitism rates through parasitoid abundance. We show that effects of tree community PD are much stronger than effects of tree species richness, can cascade to high trophic levels, and promote trophic interactions. As during habitat modification phylogenetic information is usually lost non-randomly, even species-rich habitats may not be able to continuously provide the ecosystem process parasitism if the evolutionarily most distinct plant lineages vanish. © 2016 The Author(s).

  16. Diversity Measures

    Directory of Open Access Journals (Sweden)

    MSc. Mentor Ademaj

    2012-06-01

    Full Text Available Diversity measures are a type of non-criminal measures foreseen in the Chapter IV of the Code of Juvenile Justice, which may be imposed on juvenile perpetrators of criminal acts. These measures can be applied in cases of minor offenses, for which is foreseen the criminal sanction with a fine or imprisonment up to three years or for criminal offenses committed by negligence for which is foreseen the sentence up to five years of imprisonment, except those cases that result in death. With the imposition of these measures is intended to prevent criminal proceedings against juveniles whenever is possible, rehabilitation and reintegration of juvenile in his/her community and the prevention of recidivist behaviour. Competent authority to impose them is the public prosecutor, the juvenile judge and juvenile court. And they are executed by the Kosovo Correctional Service.

  17. Randomly and Non-Randomly Missing Renal Function Data in the Strong Heart Study: A Comparison of Imputation Methods.

    Directory of Open Access Journals (Sweden)

    Nawar Shara

    Full Text Available Kidney and cardiovascular disease are widespread among populations with high prevalence of diabetes, such as American Indians participating in the Strong Heart Study (SHS. Studying these conditions simultaneously in longitudinal studies is challenging, because the morbidity and mortality associated with these diseases result in missing data, and these data are likely not missing at random. When such data are merely excluded, study findings may be compromised. In this article, a subset of 2264 participants with complete renal function data from Strong Heart Exams 1 (1989-1991, 2 (1993-1995, and 3 (1998-1999 was used to examine the performance of five methods used to impute missing data: listwise deletion, mean of serial measures, adjacent value, multiple imputation, and pattern-mixture. Three missing at random models and one non-missing at random model were used to compare the performance of the imputation techniques on randomly and non-randomly missing data. The pattern-mixture method was found to perform best for imputing renal function data that were not missing at random. Determining whether data are missing at random or not can help in choosing the imputation method that will provide the most accurate results.

  18. Does balneotherapy with low radon concentration in water influence the endocrine system? A controlled non-randomized pilot study.

    Science.gov (United States)

    Nagy, Katalin; Berhés, István; Kovács, Tibor; Kávási, Norbert; Somlai, János; Bender, Tamás

    2009-08-01

    Radon bath is a well-established modality of balneotherapy for the management of degenerative musculoskeletal disorders. The present study was conducted to ascertain whether baths of relatively low (80 Bq/l) radon concentration have any influence on the functioning of the endocrine system. In the study, a non-randomized pilot study, 27 patients with degenerative musculoskeletal disorders received 30-min radon baths (of 31-32 degrees C temperature and 80 Bq/l average radon concentration) daily, for 15 days. Twenty-five patients with matching pathologies were subjected to balneotherapy according to the same protocol, using thermal water with negligible radon content (6 Bq/l). Serum thyroid stimulating hormone, prolactin, cortisol, adrenocorticotropic hormone, and dehydroepiandrosterone levels were measured before and after a balneotherapy course of 15 sessions. Comparison of the accumulated data using the Wilcoxon test did not reveal any significant difference between pre- and post-treatment values or between the two patient groups. It is noted that while the beneficial effects of balneotherapy with radon-containing water on degenerative disorders is widely known, only few data have been published in the literature on its effect on endocrine functions. The present study failed to demonstrate any substantial effect of thermal water with relatively low radon content on the functioning of the endocrine system.

  19. Aneuploidy in immortalized human mesenchymal stem cells with non-random loss of chromosome 13 in culture.

    Science.gov (United States)

    Takeuchi, Masao; Takeuchi, Kikuko; Ozawa, Yutaka; Kohara, Akihiro; Mizusawa, Hiroshi

    2009-01-01

    Aneuploidy (an abnormal number of chromosomes) is commonly observed in most human cancer cells, highlighting the need to examine chromosomal instability in tumorigenesis. Previously, the immortalized human mesenchymal stem cell line UE6E7T-3 was shown to undergo a preferential loss of one copy of chromosome 13 after prolonged culture. Here, the loss of chromosome 13 was found to be caused by chromosome missegregation during mitosis, which involved unequal segregation, exclusion of the misaligned chromosome 13 on the metaphase plate, and trapping of chromosome 13 in the midbody region, as observed by fluorescence in situ hybridization. Near-diploid aneuploidy, not tetraploidy, was the direct result. The loss of chromosome 13 was non-random, and was detected by analysis of microsatellites and single nucleotide polymorphism-based loss of heterozygosity (LOH). Of the five microsatellite loci on chromosome 13, four loci showed microsatellite instability at an early stage in culture, and LOH was apparent at a late stage in culture. These results suggest that the microsatellite mutations cause changes in centromere integrity provoking loss of this chromosome in the UE6E7T-3 cell line. Thus, these results support the use of this cell line as a useful model for understanding the mechanism of aneuploid formation in cell cultures.

  20. Treatment of age-related subfoveal neovascular membranes by teletherapy. Results of a non-randomized study

    Energy Technology Data Exchange (ETDEWEB)

    Subasi, M.; Akmansu, M.; Or, M. [Gazi Univ., Ankara (Turkey). Medical Faculty

    1999-03-01

    This investigation was designed to determine whether low-dose radiation to the macular region could influence the natural course of age-related subfoveal neovascularization. Thirty-one patients with subfoveal membranes due to age-related macular degeneration (ARMD) were treated with 12 Gy of 6 MV X-rays, and 72 patients who were untreated served as a control group. Both groups were followed-up. At six months of follow-up visual acuity was maintained in 54.8% and improved 25.8% of patients treated by radiotherapy. In the control group, visual acuity showed deterioration in 55.5%. There was a significant difference between the treated and untreated groups (p<0.01). Significant neovascular membrane regression or stabilization was recorded in 61.3% of treated patients at six months post-radiation, whereas the membranes in all. 72 control patients showed progressive enlargement. This non-randomized study suggested that low doses of radiation may be an alternative treatment for ARMD without an immediate drop in visual acuity or significant radiation morbidity. (author)

  1. Diversity, discrimination, and performance

    OpenAIRE

    Leonard, Jonathan S.; Levine, David I.

    2003-01-01

    Employee diversity may affect business performance both as a result of customer discrimination and as a result of how members of a group work with each other in teams. We test for both channels with data from more than 800 retail stores employing over 70,000 individuals matched to Census data on the demographics of the community. We find little payoff to matching employee demographics to those of potential customers except when the customers do not speak English. Although age diversity doe...

  2. 7 CFR 3565.13 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... Agency official may request and the Administrator or designee may make an exception to any requirement or... program objectives, and provided that such an exception is not inconsistent with any applicable law or...

  3. 7 CFR 4280.104 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... Efficiency Improvements Program § 4280.104 Exception authority. The Administrator may, on a case-by-case basis, make an exception to any requirement or provision of this subpart that is not inconsistent with...

  4. 7 CFR 4274.381 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... Program (IRP) § 4274.381 Exception authority. The Administrator may, in individual cases, grant an exception to any requirement or provision of this subpart which is not inconsistent with any applicable law...

  5. 8 CFR 258.2 - Exceptions.

    Science.gov (United States)

    2010-01-01

    ... longshore work at any United States port under the exceptions provided for in paragraphs (a)(2), (b), or (c... hazardous dry bulk cargo. (i) All tankers qualify for the hazardous cargo exception, including parcel tankers, except for a tanker that has been gas-freed to transport non-hazardous dry bulk commodities. (ii...

  6. 45 CFR 148.220 - Excepted benefits.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Excepted benefits. 148.220 Section 148.220 Public... FOR THE INDIVIDUAL HEALTH INSURANCE MARKET Preemption; Excepted Benefits § 148.220 Excepted benefits... provision of the benefits described in paragraphs (a) and (b) of this section (or any combination of the...

  7. [Can venous iron and tranexamic acid reduce the transfusion need? Report on a non randomized, case control study].

    Science.gov (United States)

    Essola, L; Kouégnigan Rérambiah, L; Obame, R; Issembè, H; Sima Zué, A

    2017-06-01

    To evaluate if the association of injectable iron and tranexamic acid allows a significant saving in transfusion, in cases of myomectomies and hysterectomies. This is a prospective, non randomized study done over 8 months (from January 2013 to August 2013). Were included, patients undergoing hysterectomy or myomectomy who had a hemoglobin level greater than or equal to 8g/dl and less than 12g/dl. Two groups were compared: group A consisting of patients for whom a pack red cells was ordered and the group B which patients received intravenous iron preoperatively and tranexamic acid perioperatively. The level of hemoglobin, pre- and postoperative, the average number of blood units per patient and estimated blood loss was compared. The transfusion economy was evaluated. During this period, 87 patients with a mean age of 40±9 years (range: 23 and 70years) were included according to our criteria: 44 patients in group A and 43 patients in group B. Initial mean hemoglobin in both groups was 9.1±0.7g/dl. In group B, after iron administration, the mean hemoglobin was 11.3±0.7g/dl. The average number of red blood cells received intraoperative patient in group A was 1.54±0.51. The estimated blood loss was significant greater (P=0.0002) in group A (571.6±237.1ml) than in group B (213.7±131.7ml). No transfusion was performed in group B. The association intravenous iron and tranexamic acid resulted in the reduction of transfusion requirements in our setting. It could be integrated in the strategy for sparing blood transfusion in scheduled surgery with hemorrhagic risks. Copyright © 2017. Published by Elsevier SAS.

  8. A school intervention for mental health literacy in adolescents: effects of a non-randomized cluster controlled trial

    Science.gov (United States)

    2013-01-01

    Background “Mental health for everyone” is a school program for mental health literacy and prevention aimed at secondary schools (13–15 yrs). The main aim was to investigate whether mental health literacy, could be improved by a 3-days universal education programme by: a) improving naming of symptom profiles of mental disorder, b) reducing prejudiced beliefs, and c) improving knowledge about where to seek help for mental health problems. A secondary aim was to investigate whether adolescent sex and age influenced the above mentioned variables. A third aim was to investigate whether prejudiced beliefs influenced knowledge about available help. Method This non-randomized cluster controlled trial included 1070 adolescents (53.9% boys, M age14 yrs) from three schools in a Norwegian town. One school (n = 520) received the intervention, and two schools (n = 550) formed the control group. Pre-test and follow-up were three months apart. Linear mixed models and generalized estimating equations models were employed for analysis. Results Mental health literacy improved contingent on the intervention, and there was a shift towards suggesting primary health care as a place to seek help. Those with more prejudiced beleifs did not suggest places to seek help for mental health problems. Generally, girls and older adolescents recognized symptom profiles better and had lower levels of prejudiced beliefs. Conclusions A low cost general school program may improve mental health literacy in adolescents. Gender specific programs and attention to the age and maturity of the students should be considered when mental health literacy programmes are designed and tried out. Prejudice should be addressed before imparting information about mental health issues. PMID:24053381

  9. Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes.

    Directory of Open Access Journals (Sweden)

    Kaitlin M Stimpson

    2010-08-01

    Full Text Available Genome rearrangement often produces chromosomes with two centromeres (dicentrics that are inherently unstable because of bridge formation and breakage during cell division. However, mammalian dicentrics, and particularly those in humans, can be quite stable, usually because one centromere is functionally silenced. Molecular mechanisms of centromere inactivation are poorly understood since there are few systems to experimentally create dicentric human chromosomes. Here, we describe a human cell culture model that enriches for de novo dicentrics. We demonstrate that transient disruption of human telomere structure non-randomly produces dicentric fusions involving acrocentric chromosomes. The induced dicentrics vary in structure near fusion breakpoints and like naturally-occurring dicentrics, exhibit various inter-centromeric distances. Many functional dicentrics persist for months after formation. Even those with distantly spaced centromeres remain functionally dicentric for 20 cell generations. Other dicentrics within the population reflect centromere inactivation. In some cases, centromere inactivation occurs by an apparently epigenetic mechanism. In other dicentrics, the size of the alpha-satellite DNA array associated with CENP-A is reduced compared to the same array before dicentric formation. Extra-chromosomal fragments that contained CENP-A often appear in the same cells as dicentrics. Some of these fragments are derived from the same alpha-satellite DNA array as inactivated centromeres. Our results indicate that dicentric human chromosomes undergo alternative fates after formation. Many retain two active centromeres and are stable through multiple cell divisions. Others undergo centromere inactivation. This event occurs within a broad temporal window and can involve deletion of chromatin that marks the locus as a site for CENP-A maintenance/replenishment.

  10. High-resolution characterization of sequence signatures due to non-random cleavage of cell-free DNA.

    Science.gov (United States)

    Chandrananda, Dineika; Thorne, Natalie P; Bahlo, Melanie

    2015-06-17

    High-throughput sequencing of cell-free DNA fragments found in human plasma has been used to non-invasively detect fetal aneuploidy, monitor organ transplants and investigate tumor DNA. However, many biological properties of this extracellular genetic material remain unknown. Research that further characterizes circulating DNA could substantially increase its diagnostic value by allowing the application of more sophisticated bioinformatics tools that lead to an improved signal to noise ratio in the sequencing data. In this study, we investigate various features of cell-free DNA in plasma using deep-sequencing data from two pregnant women (>70X, >50X) and compare them with matched cellular DNA. We utilize a descriptive approach to examine how the biological cleavage of cell-free DNA affects different sequence signatures such as fragment lengths, sequence motifs at fragment ends and the distribution of cleavage sites along the genome. We show that the size distributions of these cell-free DNA molecules are dependent on their autosomal and mitochondrial origin as well as the genomic location within chromosomes. DNA mapping to particular microsatellites and alpha repeat elements display unique size signatures. We show how cell-free fragments occur in clusters along the genome, localizing to nucleosomal arrays and are preferentially cleaved at linker regions by correlating the mapping locations of these fragments with ENCODE annotation of chromatin organization. Our work further demonstrates that cell-free autosomal DNA cleavage is sequence dependent. The region spanning up to 10 positions on either side of the DNA cleavage site show a consistent pattern of preference for specific nucleotides. This sequence motif is present in cleavage sites localized to nucleosomal cores and linker regions but is absent in nucleosome-free mitochondrial DNA. These background signals in cell-free DNA sequencing data stem from the non-random biological cleavage of these fragments. This

  11. Overweight and obesity in Slovak high school students and body composition indicators: a non-randomized cross-sectional study

    Directory of Open Access Journals (Sweden)

    Bibiana Vadasova

    2016-08-01

    Full Text Available Abstract Background Physical development can be considered as an indicator of the overall health status of the youth population. Currently, it appears that the increasing trend of the prevalence of obesity among children and youths has stopped in a number of countries worldwide. Studies point to the fact that adolescence is a critical period for the development of obesity. Body mass index (BMI seems to be an orientation parameter in the assessment of prevalence of obesity which is not sufficient for more accurate identification of at risk individuals. The purpose of this study was to evaluate association between BMI percentile zones as health-risk for being overweight and obese and body composition indicators in high-school students from the Prešov (Slovakia region. Methods A non-randomized cross-sectional study in high school students from the Prešov (Slovakia region was conducted. The research sample consisted of 1014 participants (boys n = 466, girls n = 549. Body composition was measured using direct segmental multi-frequency bioelectrical impedance analysis (DSM-BIA. To examine the association between obesity and selected body composition indicators, Kruskal-Wallis ANOVA and Eta2 were used. The relationship between selected body composition indicators and percentile BMI zones was determined using the Kendall tau correlation. Results In groups with different BMI percentile zones (normal weight, overweight, obese, ANOVA showed significant differences for girls and boys (p ˂.05 with high effect size (η2 ˂.26 in body weight, body fat mass index, body fat percentage, fat free mass index, fat-free mass percentage, visceral fat area, waist-to-hip ratio, waist circumference, protein mass and mineral mass. The highest degree of correlation among boys was between BMI values indicating overweight and obesity and fat free mass index and waist circumference, respectively (τ = .71, τ = .70, respectively. In girls, the highest

  12. Effectiveness of a 'Global Postural Reeducation' program for persistent Low Back Pain: a non-randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Violante Francesco S

    2010-12-01

    Full Text Available Abstract Background The aim of this non-randomized controlled trial was to evaluate the effectiveness of a Global Postural Reeducation (GPR program as compared to a Stabilization Exercise (SE program in subjects with persistent low back pain (LBP at short- and mid-term follow-up (ie. 3 and 6 months. Methods According to inclusion and exclusion criteria, 100 patients with a primary complaint of persistent LBP were enrolled in the study: 50 were allocated to the GPR group and 50 to the SE group. Primary outcome measures were Roland and Morris Disability Questionnaire (RMDQ and Oswestry Disability Index (ODI. Secondary outcome measures were lumbar Visual Analogue Scale (VAS and Fingertip-to-floor test (FFT. Data were collected at baseline and at 3/6 months by health care professionals unaware of the study. An intention to treat approach was used to analyze participants according to the group to which they were originally assigned. Results Of the 100 patients initially included in the study, 78 patients completed the study: 42 in the GPR group and 36 in the SE group. At baseline, the two groups did not differ significantly with respect to gender, age, BMI and outcome measures. Comparing the differences between groups at short- and mid-term follow-up, the GPR group revealed a significant reduction (from baseline in all outcome measures with respect to the SE group. The ordered logistic regression model showed an increased likelihood of definitive improvement (reduction from baseline of at least 30% in RMDQ and VAS scores for the GPR group compared to the SE group (OR 3.9, 95% CI 2.7 to 5.7. Conclusions Our findings suggest that a GPR intervention in subjects with persistent LBP induces a greater improvement on pain and disability as compared to a SE program. These results must be confirmed by further studies with higher methodological standards, including randomization, larger sample size, longer follow-up and subgrouping of the LBP subjects. Trial

  13. Improvement of functional constipation with kiwifruit intake in a Mediterranean patient population: An open, non-randomized pilot study

    Directory of Open Access Journals (Sweden)

    Oriol Cunillera

    2015-07-01

    Full Text Available Introduction: Kiwifruit consumption has shown to improve functional constipation in healthy elderly population, according to studies in New Zealand and China. The aim of this study was to evaluate the effect of kiwifruit intake on functional constipation in a Mediterranean patient population characterized by its distinctive nutritional habits.Material and Methods: An open, non-controlled and non-randomized longitudinal study was conducted in 46 patients with constipation (Rome III criteria. Patients monitored for five weeks: weeks 1 and 2 no kiwifruit and weeks 3-5 three kiwifruit per day (Green kiwifruit, Actinidia deliciosa var Hayward. Bristol Scale, volume of stools, and ease of defecation was self- reported daily. The evolution of the categorical variables was tested using the Bhapkar test; functional data methodology was used for continuous variables, and Generalized Estimating Equation (GEE models were adjusted.Results: The percentage of patients with ≥3 stools per week increased from 82.61% (95% CI: 69–91.2 at week 1 to 97.78% (95% CI: 87.4–99.9 at week 2 of kiwifruit intake, with 76.09% (95% CI: 61.9–86.2 responding during the first week. The reporting of stable ideal stools increased from 17.39% (95% CI: 8.8–31 at week 2 to 33.33% (95% CI: 21.3–48 at week 5. According to GEE models, the number of depositions increased significantly (p-values<0.001 in 0.398 daily units at week 1 the first week of intake, up to 0.593 daily units at week 5; significant improvements on facility in evacuation and volume of evacuation were found from the firstweek of intake (all p-values<0.001.Conclusions: The intake of three kiwifruits per day significantly improves the quality of evacuation (number of depositions, volume, consistency and ease in a Mediterranean patient population suffering from functional constipation.

  14. Run charts revisited: a simulation study of run chart rules for detection of non-random variation in health care processes.

    Science.gov (United States)

    Anhøj, Jacob; Olesen, Anne Vingaard

    2014-01-01

    A run chart is a line graph of a measure plotted over time with the median as a horizontal line. The main purpose of the run chart is to identify process improvement or degradation, which may be detected by statistical tests for non-random patterns in the data sequence. We studied the sensitivity to shifts and linear drifts in simulated processes using the shift, crossings and trend rules for detecting non-random variation in run charts. The shift and crossings rules are effective in detecting shifts and drifts in process centre over time while keeping the false signal rate constant around 5% and independent of the number of data points in the chart. The trend rule is virtually useless for detection of linear drift over time, the purpose it was intended for.

  15. Design and Baseline Findings of a Multi-site Non-randomized Evaluation of the Effect of a Health Programme on Microfinance Clients in India

    OpenAIRE

    Saha, Somen

    2013-01-01

    Microfinance is the provision of financial services for the poor. Health program through microfinance has the potential to address several access barriers to health. We report the design and baseline findings of a multi-site non-randomized evaluation of the effect of a health program on the members of two microfinance organizations from Karnataka and Gujarat states of India. Villages identified for roll-out of health services with microfinance were pair-matched with microfinance only villages...

  16. 48 CFR 39.204 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY Electronic and Information Technology 39.204 Exceptions. The... standards to the maximum extent practicable; (b) Is for a national security system; (c) Is acquired by a... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Exceptions. 39.204 Section...

  17. 7 CFR 774.24 - Exception.

    Science.gov (United States)

    2010-01-01

    ... SPECIAL PROGRAMS EMERGENCY LOAN FOR SEED PRODUCERS PROGRAM § 774.24 Exception. The Agency may grant an exception to any of the requirements of this section, if the proposed change is in the best financial interest of the Government and not inconsistent with the authorizing statute or other applicable law. ...

  18. 7 CFR 773.23 - Exception.

    Science.gov (United States)

    2010-01-01

    ... SPECIAL PROGRAMS SPECIAL APPLE LOAN PROGRAM § 773.23 Exception. The Agency may grant an exception to the security requirements of this section, if the proposed change is in the best financial interest of the Government and not inconsistent with the authorizing statute or other applicable law. ...

  19. 22 CFR 126.3 - Exceptions.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Exceptions. 126.3 Section 126.3 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS GENERAL POLICIES AND PROVISIONS... of the United States Government, the Director, Office of Defense Trade Controls may make an exception...

  20. 24 CFR 51.105 - Exceptions.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Exceptions. 51.105 Section 51.105... ENVIRONMENTAL CRITERIA AND STANDARDS Noise Abatement and Control § 51.105 Exceptions. (a) Flexibility for non... acceptability standard of 65 decibels, the Acceptable Zone may be shifted to Ldn 70 on a case-by-case basis if...

  1. 44 CFR 17.625 - Exception provision.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Exception provision. 17.625 Section 17.625 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY GENERAL GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) § 17.625 Exception...

  2. Educating Exceptional Children: Current Issue for Educators

    Science.gov (United States)

    Specht, Jacqueline

    2004-01-01

    The Oxford dictionary defines exceptionality as "forming an exception; very unusual; outstandingly good." A thesaurus provides the following synonyms: outstanding, excellent, brilliant, antonym of ordinary. In education and psychology textbooks and journals, however, it is often defined in ways that focus on limitations, with synonyms…

  3. 48 CFR 1325.103 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... FOREIGN ACQUISITION Buy American Act-Supplies 1325.103 Exceptions. (a) The designee authorized to make a... has an agreement with a foreign government providing a blanket exception to the Buy America Act is set... documentation supporting a determination that nonavailabilty of an article is likely to affect future...

  4. 29 CFR 1905.28 - Exceptions.

    Science.gov (United States)

    2010-07-01

    ... OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 Hearings § 1905.28 Exceptions. Within 20 days after service of a... 29 Labor 5 2010-07-01 2010-07-01 false Exceptions. 1905.28 Section 1905.28 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR RULES OF...

  5. 48 CFR 1503.602 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... BUSINESS PRACTICES AND PERSONAL CONFLICTS OF INTEREST Contracts with Government Employees or Organizations... Resources Management may authorize an exception, in writing, to the policy in FAR 3.601 and 1503.601 for the... shall consult with the Designated Agency Ethics Official before authorizing any exceptions. [60 FR 38505...

  6. 48 CFR 9.304 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Exceptions. 9.304 Section... CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval is not required in contracts for— (a) Research or development; (b) Products requiring qualification...

  7. Non-random mating and convergence over time for alcohol consumption, smoking, and exercise: the Nord-Trøndelag Health Study.

    Science.gov (United States)

    Ask, Helga; Rognmo, Kamilla; Torvik, Fartein Ask; Røysamb, Espen; Tambs, Kristian

    2012-05-01

    Spouses tend to have similar lifestyles. We explored the degree to which spouse similarity in alcohol use, smoking, and physical exercise is caused by non-random mating or convergence. We used data collected for the Nord-Trøndelag Health Study from 1984 to 1986 and prospective registry information about when and with whom people entered marriage/cohabitation between 1970 and 2000. Our sample included 19,599 married/cohabitating couples and 1,551 future couples that were to marry/cohabitate in the 14-16 years following data collection. All couples were grouped according to the duration between data collection and entering into marriage/cohabitation. Age-adjusted polychoric spouse correlations were used as the dependent variables in non-linear segmented regression analysis; the independent variable was time. The results indicate that spouse concordance in lifestyle is due to both non-random mating and convergence. Non-random mating appeared to be strongest for smoking. Convergence in alcohol use and smoking was evident during the period prior to marriage/cohabitation, whereas convergence in exercise was evident throughout life. Reduced spouse similarity in smoking with relationship duration may reflect secular trends.

  8. The Relationship between Faculty's Pedagogical Content Knowledge and Students' Knowledge about Diversity in Online Courses

    Science.gov (United States)

    Chaudhery, Mitali

    2012-01-01

    The purpose of this proposed study will be to examine the relationship between faculty's pedagogical content knowledge and the design of online curriculum to teach students about diversity in a higher education environment. One hundred twenty-seven faculty teaching online courses at a Midwestern state will be selected on non-random sampling to…

  9. 48 CFR 225.103 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... covered by the World Trade Organization Government Procurement Agreement, the Under Secretary of Defense...) In order not to impair integration of the military and commercial industrial base. (B) Except as...

  10. 7 CFR 1780.25 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... authority. The Administrator may, in individual cases, make an exception to any requirement or provision of this part which is not inconsistent with the authorizing statute or other applicable law and is...

  11. 7 CFR 1779.17 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... Administrator may, in individual cases, make an exception to any requirement or provision of this part which is not inconsistent with the authorizing statute or other applicable law and is determined to be in the...

  12. 7 CFR 4279.15 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... authority. The Administrator may, in individual cases, grant an exception to any requirement or provision of this subpart which is not inconsistent with any applicable law provided, the Administrator determines...

  13. 7 CFR 1775.68 - Exception authority.

    Science.gov (United States)

    2010-01-01

    ... authority. The Administrator may, in individual cases, make an exception to any requirement or provision of this part which is not inconsistent with the authorizing statute or other applicable law and is...

  14. 40 CFR 262.55 - Exception reports.

    Science.gov (United States)

    2010-07-01

    ...) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE Exports of Hazardous Waste § 262.55 Exception reports... Protection Agency, 1200 Pennsylvania Avenue, NW., Washington, DC 20460, if any of the following occurs: ...

  15. 48 CFR 825.202 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... PROGRAMS FOREIGN ACQUISITION Buy American Act-Construction Materials 825.202 Exceptions. (a) When a... HCA believes that the non-availability of an article is likely to affect future acquisitions, include...

  16. From Ethical Exceptionalism to Ethical Exceptions: The Rule and exception Model and the Changing Meaning of Ethics In German Bioregulation.

    Science.gov (United States)

    Braun, Kathrin

    2017-12-01

    Germany is an interesting case with respect to the governance of reprogenetics. It has a strong profile in the technosciences and high aims regarding the global bioeconomy, yet her regulation of human genetics, reproductive medicine and embryo research has for a long time been rather restrictive. German biopolitical exceptionalism has often been explained by reference to Catholicism and the legacy of the Nazi past. The Germans, so goes the common story, have learnt the lessons of history and translated them into unconditional respect for human dignity, which in turn translates into unconditional protection of human life, including the human embryo, and the firm repudiation of any eugenic distinction between 'life worth to live' and 'life not worth to live'. This, however, is not the whole story. Alongside deontological strictness we find another strand of governing body politics and reprogenetics in Germany, the rule-and-exception model, running from the mid-1970s abortion law via the 2002 Stem Cell Act to the 2011 regulation of pre-implantation genetic diagnosis. In contrast to the former, that strongly draws on Kant and his concept of human dignity, the latter bears resemblances to Carl Schmitt's concept of state of exception. The article will show that the rule-and-exception model builds the exception into the rule and transforms the meaning and mandate of ethics, namely from safeguarding ethical standards to deciding about the exception. Given that the exception has now tended to become the rule, the question is whether the lessons of history will govern German reprogenetics for much longer. © 2016 John Wiley & Sons Ltd.

  17. Adapting American Policymaking to Overcome American Exceptionalism

    Science.gov (United States)

    2015-04-13

    discomfort at President Bush’s rallying good against evil speeches and the words of the NSS. The President’s us versus them foreign policies...of global leadership, and of concern for the well being of the global community. Classically, American exceptionalism refers to the uniquely free ...longer that force for good, but a force for its own good. Exceptionalism once meant a nation free from tyrannical rule and offering of bountiful

  18. 28 CFR 73.2 - Exceptions.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Exceptions. 73.2 Section 73.2 Judicial... GOVERNMENTS § 73.2 Exceptions. (a) The exemption provided in 18 U.S.C. 951(d)(4) for a “legal commercial...-89, 54 FR 46608, Nov. 6, 1989, as amended by Order No. 3018-2008, 73 FR 73182, Dec. 2, 2008] ...

  19. Diversity management

    OpenAIRE

    Knákalová, Lucie

    2009-01-01

    The key topic of the work is diversity management, i.e. management of em-ployees" diversity within organization. Opening part of the work identifies the position of diversity within society and related phenomena such as stereotypes, biases and various forms of discrimination. Then the work discusses the role of diversity management in organizations, its principles and basic areas of focus. Attention is paid to certain social groups that the diversity management concept should especially deal ...

  20. Statistical tests to compare motif count exceptionalities

    Directory of Open Access Journals (Sweden)

    Vandewalle Vincent

    2007-03-01

    Full Text Available Abstract Background Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs are identified and represent candidate functional motifs. The present work addresses the related question of comparing the exceptionality of one motif in two different sequences. Just comparing the motif count p-values in each sequence is indeed not sufficient to decide if this motif is significantly more exceptional in one sequence compared to the other one. A statistical test is required. Results We develop and analyze two statistical tests, an exact binomial one and an asymptotic likelihood ratio test, to decide whether the exceptionality of a given motif is equivalent or significantly different in two sequences of interest. For that purpose, motif occurrences are modeled by Poisson processes, with a special care for overlapping motifs. Both tests can take the sequence compositions into account. As an illustration, we compare the octamer exceptionalities in the Escherichia coli K-12 backbone versus variable strain-specific loops. Conclusion The exact binomial test is particularly adapted for small counts. For large counts, we advise to use the likelihood ratio test which is asymptotic but strongly correlated with the exact binomial test and very simple to use.

  1. Growth-induced strong pinning sites in laser ablated YBa2Cu3O7-δ films with a non-random distribution

    International Nuclear Information System (INIS)

    Huijbregtse, J.M.; Klaassen, F.C.; Geest, R.C.F. van der; Dam, B.; Griessen, R.

    1999-01-01

    Recently, the authors showed that natural linear defects are the origin of the high critical currents in laser ablated YGBa 2 Cu 3 O 7-δ films. Combining wet-chemical etching and Atomic Force Microscopy, they find that these dislocations are created by island coalescence during growth. Consequently, the defect density can be reproducibly varied by manipulating the density of growth islands, which in turn depends on the substrate temperature. Interestingly, the radial defect distribution function approaches zero at small distances, indicating short range order. Therefore, they are now able to study vortex matter in films with a tailored non-random distribution of natural strong pinning sites

  2. Post-exceptionalism in public policy

    DEFF Research Database (Denmark)

    Daugbjerg, Carsten; Feindt, Peter H.

    2017-01-01

    Framing the special issue on the transformation of Food and Agricultural Policy, this article introduces the concept of post-exceptionalism in public policies. The analysis of change in agri-food policy serves as a generative example to conceptualize current transformations in sectoral policy...... arrangements in democratic welfare states. Often these arrangements have been characterized by an exceptionalist ideational framework that legitimizes a sector’s special treatment through compartmentalized, exclusive and producer-centered policies and politics. In times of internationalization of policy......-making, increasing interlinkage of policy areas and trends towards self-regulation, liberalization and performance-based policies, policy exceptionalism is under pressure to either transform or give way to (neo-)liberal policy arrangements. Post-exceptionalism denotes a partial transformation of exceptionalist ideas...

  3. Amendments to excepted benefits. Final rules.

    Science.gov (United States)

    2014-10-01

    This document contains final regulations that amend the regulations regarding excepted benefits under the Employee Retirement Income Security Act of 1974, the Internal Revenue Code (the Code), and the Public Health Service Act. Excepted benefits are generally exempt from the health reform requirements that were added to those laws by the Health Insurance Portability and Accountability Act and the Patient Protection and Affordable Care Act. In addition, eligibility for excepted benefits does not preclude an individual from eligibility for a premium tax credit under section 36B of the Code if an individual chooses to enroll in coverage under a Qualified Health Plan through an Affordable Insurance Exchange. These regulations finalize some but not all of the proposed rules with minor modifications; additional guidance on limited wraparound coverage is forthcoming.

  4. Diversity Index

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — This map service summarizes racial and ethnic diversity in the United States in 2012.The Diversity Index shows the likelihood that two persons chosen at random from...

  5. Managing Diversity.

    Science.gov (United States)

    Geber, Beverly

    1990-01-01

    Demographic trends imply that organizations must learn to manage a diverse work force. Ways to change organizational systems, structures, and practices to eliminate subtle barriers are awareness training, attitude change, and valuing diversity. (SK)

  6. Session-based Choreography with Exceptions

    DEFF Research Database (Denmark)

    Carbone, Marco

    2009-01-01

    Choreography has recently emerged as a pragmatic and concise way of describing communication-based systems such as web services and financial protocols. Recent studies have investigated the transition from the design stage of a system to its implementation providing an automatic way of mapping...... a choreograhy into executable code. In this work, we focus on an extension of choreography with a communication-based (interactional) exception mechanism by giving its formal semantics. In particular, we discuss through some examples how interactional exceptions at choreography level can be implemented into end...

  7. A geometric formulation of exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Bosque, Pascal du [Arnold Sommerfeld Center for Theoretical Physics,Department für Physik, Ludwig-Maximilians-Universität München,Theresienstraße 37, 80333 München (Germany); Max-Planck-Institut für Physik, Werner-Heisenberg-Institut, Föhringer Ring 6, 80805 München (Germany); Hassler, Falk [Department of Physics and Astronomy, University of North Carolina, Phillips Hall, CB #3255, 120 E. Cameron Ave., Chapel Hill, NC 27599-3255 (United States); City University of New York, The Graduate Center, 365 Fifth Avenue, New York, NY 10016 (United States); Department of Physics, Columbia University, Pupin Hall, 550 West 120th St., New York, NY 10027 (United States); Lüst, Dieter [Arnold Sommerfeld Center for Theoretical Physics,Department für Physik, Ludwig-Maximilians-Universität München,Theresienstraße 37, 80333 München (Germany); Max-Planck-Institut für Physik, Werner-Heisenberg-Institut, Föhringer Ring 6, 80805 München (Germany); Malek, Emanuel [Arnold Sommerfeld Center for Theoretical Physics,Department für Physik, Ludwig-Maximilians-Universität München,Theresienstraße 37, 80333 München (Germany)

    2017-03-01

    We formulate the full bosonic SL(5) exceptional field theory in a coordinate-invariant manner. Thereby we interpret the 10-dimensional extended space as a manifold with SL(5)×ℝ{sup +}-structure. We show that the algebra of generalised diffeomorphisms closes subject to a set of closure constraints which are reminiscent of the quadratic and linear constraints of maximal seven-dimensional gauged supergravities, as well as the section condition. We construct an action for the full bosonic SL(5) exceptional field theory, even when the SL(5)×ℝ{sup +}-structure is not locally flat.

  8. Rethinking Diversity.

    Science.gov (United States)

    1996

    These three papers were presented at a symposium on rethinking diversity in human resource development (HRD) moderated by Neal Chalofsky at the 1996 conference of the Academy of Human Resource Development. "Diversity: A Double-Edged Sword" (Sally F. Angus) presents the notion of work force diversity through two differing perspectives in order to…

  9. 29 CFR 1921.14 - Exceptions.

    Science.gov (United States)

    2010-07-01

    ... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) RULES OF PRACTICE IN ENFORCEMENT PROCEEDINGS UNDER SECTION 41 OF THE LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT Decision and Order § 1921.14 Exceptions. Within 20 days after the date of the decision of the...

  10. A Priceless Playground for Exceptional Children.

    Science.gov (United States)

    Adkins, Patricia G.

    Described are 20 pieces of therapeutic playground equipment constructed by volunteers and fathers of children in the Early Learning Center for Exceptional Children (El Paso, Texas). It is noted that discarded and readily available materials (such as old tires) were used, and that no commercial playground equipment was purchased. Information on the…

  11. 15 CFR 1180.7 - Exceptions.

    Science.gov (United States)

    2010-01-01

    ... Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) TECHNOLOGY... INFORMATION TO THE NATIONAL TECHNICAL INFORMATION SERVICE § 1180.7 Exceptions. (a) An agency shall not be...) The product is an agency generated article that is published in a privately produced journal; or (5...

  12. Exceptional polynomials and SUSY quantum mechanics

    Indian Academy of Sciences (India)

    Abstract. We show that for the quantum mechanical problem which admit classical Laguerre/. Jacobi polynomials as solutions for the Schrödinger equations (SE), will also admit exceptional. Laguerre/Jacobi polynomials as solutions having the same eigenvalues but with the ground state missing after a modification of the ...

  13. 48 CFR 725.403 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... Section 725.403 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Trade Agreements 725.403 Exceptions. FAR 25.4 establishes procedures for purchases under the Trade Agreements Act of 1979 (including GATT's Agreement on Government Procurement) and...

  14. 26 CFR 1.306-2 - Exception.

    Science.gov (United States)

    2010-04-01

    ... is the avoidance of Federal income tax. [T.D. 6500, 25 FR 11607, Nov. 26, 1960, as amended by T.D... Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Recipients § 1.306-2 Exception. (a) If a shareholder terminates his entire stock...

  15. 48 CFR 825.103 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... article is likely to affect future acquisitions, include a recommendation that a copy of the determination... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Exceptions. 825.103 Section 825.103 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SOCIOECONOMIC...

  16. 48 CFR 225.7003-3 - Exceptions.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Exceptions. 225.7003-3 Section 225.7003-3 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... the recommendation of the Strategic Materials Protection Board pursuant to 10 U.S.C. 187, determines...

  17. Working with Navajo Parents of Exceptional Children.

    Science.gov (United States)

    Jones, Doris; And Others

    Undergraduate students at Northern Arizona University interviewed and surveyed 20 staff members at Kayenta Unified School District (KUSD) on the Navajo Reservation and 14 parents of exceptional Navajo children enrolled in KUSD. Both groups were asked to identify challenges affecting the working relationship between parents and school on a rural…

  18. 31 CFR 211.3 - Exceptions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Exceptions. 211.3 Section 211.3 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE DELIVERY OF CHECKS AND WARRANTS TO ADDRESSES OUTSIDE THE...

  19. Voices from the Classroom: Exceptional Teachers Speak.

    Science.gov (United States)

    Maeroff, Gene I., Ed.

    The opinions and experiences reflected in this report are those of exceptional teachers chosen in a national competition, "Thanks to Teachers," sponsored by Apple Computer, Inc., the National Foundation for the Improvement of Education, the National Alliance of Business, and Group W Television. The report is divided into four sections: (1) the…

  20. Lifestyle factors of people with exceptional longevity.

    Science.gov (United States)

    Rajpathak, Swapnil N; Liu, Yingheng; Ben-David, Orit; Reddy, Saritha; Atzmon, Gil; Crandall, Jill; Barzilai, Nir

    2011-08-01

    To assess lifestyle factors including physical activity, smoking, alcohol consumption, and dietary habits in men and women with exceptional longevity. Retrospective cohort study. A cohort of community-dwelling Ashkenazi Jewish individuals with exceptional longevity defined as survival and living independently at age 95 and older. Four hundred seventy-seven individuals (mean 97.3 ± 2.8, range 95-109; 74.6% women) and a subset of participants of the National Health and Nutrition Examination Survey (NHANES) I (n = 3,164) representing the same birth cohort as a comparison group. A trained interviewer administrated study questionnaires to collect information on lifestyle factors and collected data on anthropometry. People with exceptional longevity had similar mean body mass index (men, 25.4 ± 2.8 kg/m² vs 25.6 ± 4.0 kg/m² , P=.63; women, 25.0 ± 3.5 kg/m² vs 24.9 ± 5.4 kg/m² ; P = .90) and a similar proportion of daily alcohol consumption (men, 23.9 vs 22.4, P = .77; women, 12.1 vs 11.3, P = .80), of regular physical activity (men: 43.1 vs 57.2; P = .07; women: 47.0 vs 44.1, P = .76), and of a low-calorie diet (men: 20.8 vs 21.1, P=.32; women: 27.3 vs 27.1, P=.14) as the NHANES I population. People with exceptional longevity are not distinct in terms of lifestyle factors from the general population, suggesting that people with exceptional longevity may interact with environmental factors differently than others. This requires further investigation. © 2011, Copyright the Authors. Journal compilation © 2011, The American Geriatrics Society.

  1. Cognitive function in families with exceptional survival

    DEFF Research Database (Denmark)

    Barral, Sandra; Cosentino, Stephanie; Costa, Rosann

    2012-01-01

    members in the offspring generation demonstrate significantly better performance on multiple tasks requiring attention, working memory, and semantic processing when compared with individuals without a family history of exceptional survival, suggesting that cognitive performance may serve as an important......The authors investigated whether cognitive function may be used as an endophenotype for longevity by assessing the cognitive performance of a family-based cohort consisting of 1380 individuals from 283 families recruited for exceptional survival in field centers in Boston, New York, Pittsburgh......, and Denmark. Cognitive performance was assessed in the combined offspring of the Long Life Family Study (LLFS) probands and their LLFS siblings as compared with their spouses' cognitive performance. Our results indicate that the combined offspring of the LLFS probands and their siblings achieve significantly...

  2. Global Trade issues and Cultural Exception

    Directory of Open Access Journals (Sweden)

    Vanessa MARSON

    2012-01-01

    Full Text Available Cultural exception has always been a key element in the French political and cultural field. It isbased on the principle that culture is not like any other merchandise because it goes beyond thecommercial. During the negotiations of the Uruguay Round (1986-1994 the United States offeredto liberalize cultural goods and services. Due to the sensitive nature of the cultural industries, theEuropean Union led by France refused to make an offer of liberalization on these fields. Afterheated debates between the United States and the European Union, cultural exception has finallybecome a global issue since 2005. On 20 October, the UNESCO convention on cultural diversitywas voted by 148 countries to two (The United States and Israel to legally and globally recognizethe specific nature of cultural goods and services in the liberalization process.

  3. Identity, Diversity and Diversity Management

    DEFF Research Database (Denmark)

    Holck, Lotte; Muhr, Sara Louise; Villeseche, Florence

    2016-01-01

    – The work can encourage policy makers, diversity and HR managers to question their own practices and assumptions leading to more theoretical informed diversity management practices. Originality/value – The theoretical connections between identity and diversity literature have so far not been reviewed......The purpose of this paper is to examine the relationship between the identity and diversity literatures and discuss how a better understanding of the theoretical connections between the two informs both diversity research and diversity management practices. Design/methodology/approach – Literature...... and limitations – is crucial for successful diversity management research and practice. Research limitations/implications – The authors argue for a better understanding of differences, overlaps and limits of different identity perspectives, and for a stronger engagement with practice. Practical implications...

  4. Exceptional Complex Chromosomal Rearrangements in Three Generations

    Directory of Open Access Journals (Sweden)

    Hannie Kartapradja

    2015-01-01

    Full Text Available We report an exceptional complex chromosomal rearrangement (CCR found in three individuals in a family that involves 4 chromosomes with 5 breakpoints. The CCR was ascertained in a phenotypically abnormal newborn with additional chromosomal material on the short arm of chromosome 4. Maternal karyotyping indicated that the mother carried an apparently balanced CCR involving chromosomes 4, 6, 11, and 18. Maternal transmission of the derivative chromosome 4 resulted in partial trisomy for chromosomes 6q and 18q and a partial monosomy of chromosome 4p in the proband. Further family studies found that the maternal grandmother carried the same apparently balanced CCR as the proband’s mother, which was confirmed using the whole chromosome painting (WCP FISH. High resolution whole genome microarray analysis of DNA from the proband’s mother found no evidence for copy number imbalance in the vicinity of the CCR translocation breakpoints, or elsewhere in the genome, providing evidence that the mother’s and grandmother’s CCRs were balanced at a molecular level. This structural rearrangement can be categorized as an exceptional CCR due to its complexity and is a rare example of an exceptional CCR being transmitted in balanced and/or unbalanced form across three generations.

  5. Exceptional points in open quantum systems

    International Nuclear Information System (INIS)

    Mueller, Markus; Rotter, Ingrid

    2008-01-01

    Open quantum systems are embedded in the continuum of scattering wavefunctions and are naturally described by non-Hermitian Hamilton operators. In the complex energy plane, exceptional points appear at which two (or more) eigenvalues of the Hamilton operator coalesce. Although they are a countable set of single points in the complex energy plane and therefore of measure zero, they determine decisively the dynamics of open quantum systems. A powerful method for the description of open quantum systems is the Feshbach projection operator formalism. It is used in the present paper as a basic tool for the study of exceptional points and of the role they play for the dynamics of open quantum systems. Among others, the topological structure of the exceptional points, the rigidity of the phases of the eigenfunctions in their vicinity, the enhancement of observable values due to the reduced phase rigidity and the appearance of phase transitions are considered. The results are compared with existing experimental data on microwave cavities. In the last section, some questions being still unsolved, are considered

  6. Probability calculus of fractional order and fractional Taylor's series application to Fokker-Planck equation and information of non-random functions

    International Nuclear Information System (INIS)

    Jumarie, Guy

    2009-01-01

    A probability distribution of fractional (or fractal) order is defined by the measure μ{dx} = p(x)(dx) α , 0 α (D x α h α )f(x) provided by the modified Riemann Liouville definition, one can expand a probability calculus parallel to the standard one. A Fourier's transform of fractional order using the Mittag-Leffler function is introduced, together with its inversion formula; and it provides a suitable generalization of the characteristic function of fractal random variables. It appears that the state moments of fractional order are more especially relevant. The main properties of this fractional probability calculus are outlined, it is shown that it provides a sound approach to Fokker-Planck equation which are fractional in both space and time, and it provides new results in the information theory of non-random functions.

  7. Urinary Diversion

    Science.gov (United States)

    ... only exceptions may be contact sports such as football or karate. Patients whose jobs include strenuous physical ... Process Research Training & Career Development Funded Grants & Grant History Research Resources Research at NIDDK Technology Advancement & Transfer ...

  8. Exceptional Points and Dynamical Phase Transitions

    Directory of Open Access Journals (Sweden)

    I. Rotter

    2010-01-01

    Full Text Available In the framework of non-Hermitian quantum physics, the relation between exceptional points,dynamical phase transitions and the counter intuitive behavior of quantum systems at high level density is considered. The theoretical results obtained for open quantum systems and proven experimentally some years ago on a microwave cavity, may explain environmentally induce deffects (including dynamical phase transitions, which have been observed in various experimental studies. They also agree(qualitatively with the experimental results reported recently in PT symmetric optical lattices.

  9. Exceptional Drought and Unconventional Energy Production

    Directory of Open Access Journals (Sweden)

    Reid B. Stevens

    2018-04-01

    Full Text Available The hydraulic fracturing boom in Texas required massive water flows. Beginning in the summer of 2011, water became scarce as a prolonged heat wave and subsequent severe drought spread across the state. Oil and gas producers working in drought areas needed to purchase expensive local water or transport water from a non-drought county far from the drill site. In response to decreased water availability in drought areas, these producers completed fewer wells and completed wells that used less water. This decrease in well-level water use had a measurable effect on the amount of oil and gas produced by wells completed during exceptional conditions.

  10. Generalized IIB supergravity from exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Baguet, Arnaud; Magro, Marc; Samtleben, Henning [Laboratoire de Physique, Université Claude Bernard Lyon 1, Ens de Lyon, CNRS,F-69342 Lyon (France)

    2017-03-20

    The background underlying the η-deformed AdS{sub 5}×S{sup 5} sigma-model is known to satisfy a generalization of the IIB supergravity equations. Their solutions are related by T-duality to solutions of type IIA supergravity with non-isometric linear dilaton. We show how the generalized IIB supergravity equations can be naturally obtained from exceptional field theory. Within this manifestly duality covariant formulation of maximal supergravity, the generalized IIB supergravity equations emerge upon imposing on the fields a simple Scherk-Schwarz ansatz which respects the section constraint.

  11. Quartic trace identity for exceptional Lie algebras

    International Nuclear Information System (INIS)

    Okubo, S.

    1979-01-01

    Let X be a representation matrix of generic element x of a simple Lie algebra in generic irreducible representation ]lambda] of the Lie algebra. Then, for all exceptional Lie algebras as well as A 1 and A 2 , we can prove the validity of a quartic trace identity Tr(X 4 ) =K (lambda)[Tr(X 2 )] 2 , where the constant K (lambda) depends only upon the irreducible representation ]lambda], and its explicit form is calculated. Some applications of second and fourth order indices have also been discussed

  12. Diversity Management

    DEFF Research Database (Denmark)

    Ravazzani, Silvia

    2018-01-01

    This entry provides an overview of diversity management which, in the context of organizations, consists in the strategic process of harnessing the potential of all employees to create an inclusive environment and, at the same time, contribute to meeting organizational goals. The entry first...... describes the complex construct of diversity that has been variously conceptualized in the literature, embracing multiple social and informational diversity dimensions such as gender, age, culture, values, and workstyle. This is followed by illustration of the historical development of diversity-management...... discourse and practice, and possible overarching approaches guiding organizations. It goes on to elucidate elements linked to the implementation of diversity management: positive and negative outcomes, most spread practices including communication, and contingency factors shaping the understanding...

  13. Exceptional quantum geometry and particle physics

    Directory of Open Access Journals (Sweden)

    Michel Dubois-Violette

    2016-11-01

    Full Text Available Based on an interpretation of the quark–lepton symmetry in terms of the unimodularity of the color group SU(3 and on the existence of 3 generations, we develop an argumentation suggesting that the “finite quantum space” corresponding to the exceptional real Jordan algebra of dimension 27 (the Euclidean Albert algebra is relevant for the description of internal spaces in the theory of particles. In particular, the triality which corresponds to the 3 off-diagonal octonionic elements of the exceptional algebra is associated to the 3 generations of the Standard Model while the representation of the octonions as a complex 4-dimensional space C⊕C3 is associated to the quark–lepton symmetry (one complex for the lepton and 3 for the corresponding quark. More generally it is suggested that the replacement of the algebra of real functions on spacetime by the algebra of functions on spacetime with values in a finite-dimensional Euclidean Jordan algebra which plays the role of “the algebra of real functions” on the corresponding almost classical quantum spacetime is relevant in particle physics. This leads us to study the theory of Jordan modules and to develop the differential calculus over Jordan algebras (i.e. to introduce the appropriate notion of differential forms. We formulate the corresponding definition of connections on Jordan modules.

  14. Exceptional confinement in G(2) gauge theory

    International Nuclear Information System (INIS)

    Holland, K.; Minkowski, P.; Pepe, M.; Wiese, U.-J.

    2003-01-01

    We study theories with the exceptional gauge group G(2). The 14 adjoint 'gluons' of a G(2) gauge theory transform as {3}, {3-bar} and {8} under the subgroup SU(3), and hence have the color quantum numbers of ordinary quarks, anti-quarks and gluons in QCD. Since G(2) has a trivial center, a 'quark' in the {7} representation of G(2) can be screened by 'gluons'. As a result, in G(2) Yang-Mills theory the string between a pair of static 'quarks' can break. In G(2) QCD there is a hybrid consisting of one 'quark' and three 'gluons'. In supersymmetric G(2) Yang-Mills theory with a {14} Majorana 'gluino' the chiral symmetry is Z(4) χ . Chiral symmetry breaking gives rise to distinct confined phases separated by confined-confined domain walls. A scalar Higgs field in the {7} representation breaks G(2) to SU(3) and allows us to interpolate between theories with exceptional and ordinary confinement. We also present strong coupling lattice calculations that reveal basic features of G(2) confinement. Just as in QCD, where dynamical quarks break the Z(3) symmetry explicitly, G(2) gauge theories confine even without a center. However, there is not necessarily a deconfinement phase transition at finite temperature

  15. Is There Muslim Exceptionalism in Democracy Research?

    DEFF Research Database (Denmark)

    Hariri, Jacob Gerner

    to and between the 16th and 18th centuries are relatively less democratic today. The negative effect of early statehood on current levels of democracy is mediated by European colonization and settlement: Europeans were less likely to colonize and settle in territories with more developed state institutions......, also, to alternative theories of the causes and correlates of democracy. This paper presents evidence against the notion of Muslim exceptionalism in democracy research. Thus, outside the European continent, territories that were governed earlier and more consistently by state organizations up...... and were therefore less likely to bring nascent legalistic and representative institutions to these territories. When we remove the autocratic legacy of early statehood and the influence of European settlement, there is nothing signicantly negative about the degree of democracy in Muslim-majority countries....

  16. Transporting "exceptional cargo" on the CERN sites

    CERN Multimedia

    EN Department

    2012-01-01

    When the Transport Service is managing "exceptional cargo", the driver and the escort are often in charge of an operation involving equipment worth many hundred thousand francs. Equipment that may well be irreplaceable for a facility or an experiment.   The members of the Transport Service who carry out these tasks are very professional and are – needless to say – highly concentrated on the job. They count on your understanding and support in the traffic on site. Their convoys are – for good reasons – moving slowly. Kindly do not overtake, do not cut in in front of them and do not drive too closely. Respect the escort and do not position yourself between the truck and the escort vehicles. The EN department counts on your courtesy on the road.  

  17. Unidirectional reflectionless light propagation at exceptional points

    Directory of Open Access Journals (Sweden)

    Huang Yin

    2017-05-01

    Full Text Available In this paper, we provide a comprehensive review of unidirectional reflectionless light propagation in photonic devices at exceptional points (EPs. EPs, which are branch point singularities of the spectrum, associated with the coalescence of both eigenvalues and corresponding eigenstates, lead to interesting phenomena, such as level repulsion and crossing, bifurcation, chaos, and phase transitions in open quantum systems described by non-Hermitian Hamiltonians. Recently, it was shown that judiciously designed photonic synthetic matters could mimic the complex non-Hermitian Hamiltonians in quantum mechanics and realize unidirectional reflection at optical EPs. Unidirectional reflectionlessness is of great interest for optical invisibility. Achieving unidirectional reflectionless light propagation could also be potentially important for developing optical devices, such as optical network analyzers. Here, we discuss unidirectional reflectionlessness at EPs in both parity-time (PT-symmetric and non-PT-symmetric optical systems. We also provide an outlook on possible future directions in this field.

  18. Leibniz algebroids, twistings and exceptional generalized geometry

    Science.gov (United States)

    Baraglia, D.

    2012-05-01

    We investigate a class of Leibniz algebroids which are invariant under diffeomorphisms and symmetries involving collections of closed forms. Under appropriate assumptions we arrive at a classification which in particular gives a construction starting from graded Lie algebras. In this case the Leibniz bracket is a derived bracket and there are higher derived brackets resulting in an L∞-structure. The algebroids can be twisted by a non-abelian cohomology class and we prove that the twisting class is described by a Maurer-Cartan equation. For compact manifolds we construct a Kuranishi moduli space of this equation which is shown to be affine algebraic. We explain how these results are related to exceptional generalized geometry.

  19. Chamaedorea: diverse species in diverse habitats

    Directory of Open Access Journals (Sweden)

    1992-01-01

    Full Text Available DIVERSES ESPÈCES DANS DIVERS HABITATS. Des espèces extraordinairement diverses se trouvant dans des habitats également divers caractérisent Chamaedorea, un genre qui compte environ 90 espèces dioïques limitées aux sous-bois des forêts néo-tropicales constamment dans la pluie et les nuages du Mexique à la Bolivie et à l’Équateur. Une vaste gamme de formes biologiques, de tiges, de feuilles, d’inflorescences, de fleurs, et de fruits reflète la diversité des espèces. Bien que le genre soit plus riche en espèces dans les forêts denses et humides situées entre 800-1,500 mètres d’altitude, quelques espèces exceptionnelles se trouvent dans des forêts moins denses et/ou occasionnellement sèches, sur des substances dures ou dans d’autres habitats inhabituels. DIVERSAS ESPECIES EN DIVERSOS HÁBITATS. Especies notablemente diversas presentes en habitats igualmente diversos caracterizan a Chamaedorea, un genero de aproximadamente 90 especies dioicas limitadas al sotobosque de los bosques lluviosos y nubosos neotropicales desde Mexico hasta Bolivia y Ecuador. Una amplia gama de formas biológicas, tallos, hojas, inflorescencias, flores, y frutos refleja la diversidad de las especies. Aunque el género es más rico en especies en los bosques densos y húmedos de 800-1,500 metros de altura, unas pocas especies excepcionales ocurren en bosques abiertos o ocasionalmente secos, en substrato severo o en otros habitats extraordinarios. Remarkably diverse species occurring in equally diverse habitats characterize Chamaedorea, a genus of about 90, dioecious species restricted to the understory of neotropical rain and cloud forests from Mexico to Bolivia and Ecuador. A vast array of habits, stems, leaves, inflorescences, flowers, and fruits reflect the diversity of species. Although the genus is most species-rich in dense, moist or wet, diverse forests from 800-1,500 meters elevation, a few exceptional species occur in open and/or seasonally

  20. Understanding Diversity

    NARCIS (Netherlands)

    D.L. van Knippenberg (Daan)

    2007-01-01

    textabstractDaan van Knippenberg is Professor of Organizational Behavior at RSM Erasmus University, Erasmus University Rotterdam, The Netherlands. His research interests include work group performance, especially work group diversity and group decision making, leadership, in particular the roles of

  1. [Exceptional etiology of acute renal: Burkitt's lymphoma].

    Science.gov (United States)

    Dial, Cherif; Doh, Kwame; Thiam, Ibou; Faye, Mariam; Woto-Gaye, Gisèle

    2018-02-05

    Burkitt's lymphoma (BL) is an exceptional cause of acute renal failure (ARF). The origin of the tumor clone may be lymphoid follicles secondary to renal Epstein-Barr virus (EBV) infection. With the presentation of this clinical case, the pathogenesis, diagnostic criteria and evolution of this extremely rare affection will be discussed. A 4-year-old patient with a recent history of acute osteomyelitis of the right thigh presented an ARF without indications of post-infectious glomerulonephritis. Ultrasound showed enlarged kidneys without dilation of the excretory cavities. Diffuse interstitial infiltration of atypical lymphoid cells of medium size were noted upon renal biopsy. The tumor cells expressed antibodies against CD20, CD10, Bcl6, and Ki67 but not against Bcl2 or CD3. The search for an EBV infection was positive. A few days after diagnosis, the evolution was spontaneously fatal. BL of the kidney is a rare condition that accounts for less than 1 % of kidney tumors, associated almost invariably with EBV infection. The diagnosis is confirmed histologically by renal biopsy and the criteria of Malbrain affirms the primitive character of the lymphoma. BL of the kidney is a diagnostic and therapeutic emergency and may be fatal. Copyright © 2018 Société francophone de néphrologie, dialyse et transplantation. Published by Elsevier Masson SAS. All rights reserved.

  2. Exactly marginal deformations from exceptional generalised geometry

    Energy Technology Data Exchange (ETDEWEB)

    Ashmore, Anthony [Merton College, University of Oxford,Merton Street, Oxford, OX1 4JD (United Kingdom); Mathematical Institute, University of Oxford,Andrew Wiles Building, Woodstock Road, Oxford, OX2 6GG (United Kingdom); Gabella, Maxime [Institute for Advanced Study,Einstein Drive, Princeton, NJ 08540 (United States); Graña, Mariana [Institut de Physique Théorique, CEA/Saclay,91191 Gif-sur-Yvette (France); Petrini, Michela [Sorbonne Université, UPMC Paris 05, UMR 7589, LPTHE,75005 Paris (France); Waldram, Daniel [Department of Physics, Imperial College London,Prince Consort Road, London, SW7 2AZ (United Kingdom)

    2017-01-27

    We apply exceptional generalised geometry to the study of exactly marginal deformations of N=1 SCFTs that are dual to generic AdS{sub 5} flux backgrounds in type IIB or eleven-dimensional supergravity. In the gauge theory, marginal deformations are parametrised by the space of chiral primary operators of conformal dimension three, while exactly marginal deformations correspond to quotienting this space by the complexified global symmetry group. We show how the supergravity analysis gives a geometric interpretation of the gauge theory results. The marginal deformations arise from deformations of generalised structures that solve moment maps for the generalised diffeomorphism group and have the correct charge under the generalised Reeb vector, generating the R-symmetry. If this is the only symmetry of the background, all marginal deformations are exactly marginal. If the background possesses extra isometries, there are obstructions that come from fixed points of the moment maps. The exactly marginal deformations are then given by a further quotient by these extra isometries. Our analysis holds for any N=2 AdS{sub 5} flux background. Focussing on the particular case of type IIB Sasaki-Einstein backgrounds we recover the result that marginal deformations correspond to perturbing the solution by three-form flux at first order. In various explicit examples, we show that our expression for the three-form flux matches those in the literature and the obstruction conditions match the one-loop beta functions of the dual SCFT.

  3. Stem cell policy exceptionalism: proceed with caution.

    Science.gov (United States)

    Lomax, Geoffrey P; Peckman, Steven R

    2012-06-01

    The term "stem cell exceptionalism" has been used to characterize the policy response to controversies surrounding human embryonic stem cell research. For example, governments and funding agencies have adopted policies governing the derivation and use of human embryonic stem cell lines. These policies have effectively served to fill gaps in existing guidelines and regulations and signal that scientists are committed to a responsible framework for the conduct of research involving human embryos. Recent publications discuss whether ethical and policy issues associated with induced pluripotent cells (iPSCs) from non-embryonic sources create a need for further policy intervention. We suggest many of the issues identified by commentators may be addressed through the application of established policy frameworks governing the use of tissue, human stem cells, and research participation by human research subjects. To the extent, iPSC research intersects with hESC research (e.g. the creation of human gametes and/or embryos), the policy framework governing hESC appears sufficiently robust at this time.

  4. Exceptionally elevated triglyceride in severe lipemia retinalis

    Directory of Open Access Journals (Sweden)

    Yin HY

    2016-10-01

    Full Text Available Han Y Yin,1–3 Roberto Warman,2,4 Edward H Suh,2 Anny MS Cheng2,3 1Wayne State University, School of Medicine, Detroit, MI, 2Department of Ophthalmology, Florida International University, Herbert Wertheim College of Medicine, 3Ocular Surface Center, Miami, 4Division of Pediatric Ophthalmology, Nicklaus Children’s Hospital, Miami, FL, USA Purpose: To report a case of successful treatment for severe lipemia retinalis with extreme severe hypertriglyceridemia (sHTG.Design: Observational case report.Observations: A 6-week-old infant with severe lipemia retinalis manifested diffuse creamy retinal vessels complicated with vulvar xanthomas. Extreme sHTG with 185-folds of the normal level was reported. Chromosome microarray and lipid gene sequencing confirmed a homozygous lipoprotein lipase gene coding mutation.Results: Under strict adherence to a high medium-chain triglycerides formula and discontinuation of breast milk, the lipemia retinalis and vulval lesions resolved along with a stable plasma lipid level throughout the follow-up period of 6 months.Conclusion: Strict adherence to a low-fat diet without breast milk appears to be effective in treating infants with severe lipemia retinalis associated with exceptionally high triglycerides. Keywords: hypertriglyceride, infant, lipemia retinalis, lipoprotein lipase gene

  5. An open-label, non-randomized comparison of venlafaxine and gabapentin as monotherapy or adjuvant therapy in the management of neuropathic pain in patients with peripheral neuropathy

    Directory of Open Access Journals (Sweden)

    William Eardley

    2010-04-01

    Full Text Available William Eardley, Cory TothDepartment of Clinical Neurosciences and the University of Calgary, Calgary, AB, CanadaAbstract: Although many therapies are used in the management of neuropathic pain (NeP due to polyneuropathy (PN, few comparison studies exist. We performed a prospective, non-randomized, unblended, efficacy comparison of the serotonin-norepinephrine reuptake inhibitor venlafaxine, as either monotherapy or adjuvant therapy, with a first-line medication for NeP, gabapentin, in patients with PN-related NeP. VAS pain scores were assessed after 3 and 6 months in intervention groups and in a cohort of patients receiving no pharmacotherapy. In a total of 223 patients, we analyzed pain quantity and quality (visual analogue scale [VAS] score, Brief Pain Inventory [BPI], quality of life and health status measures [EuroQol 5 Domains, EQ-5D], Medical Outcomes Sleep Study Scale [MOSSS], Hospital Anxiety and Depression Scale [HADS] and Short Form 36 Health Survey [SF-36] after 6 months of therapy. Significant improvements in VAS pain scores occurred for all treatment groups after 6 months. Improvements in aspects of daily life and anxiety were identified in all treatment groups. Our data suggest that monotherapy or adjuvant therapy with venlafaxine is comparable to gabapentin for NeP management. We advocate for head-to-head, randomized, double-blinded studies of current NeP therapies.Keywords: peripheral neuropathy, neuropathic pain, pharmacotherapy, venlafaxine, gabapentin

  6. Validation of the k-filtering technique for a signal composed of random-phase plane waves and non-random coherent structures

    Directory of Open Access Journals (Sweden)

    O. W. Roberts

    2014-12-01

    Full Text Available Recent observations of astrophysical magnetic fields have shown the presence of fluctuations being wave-like (propagating in the plasma frame and those described as being structure-like (advected by the plasma bulk velocity. Typically with single-spacecraft missions it is impossible to differentiate between these two fluctuations, due to the inherent spatio-temporal ambiguity associated with a single point measurement. However missions such as Cluster which contain multiple spacecraft have allowed for temporal and spatial changes to be resolved, using techniques such as k filtering. While this technique does not assume Taylor's hypothesis it requires both weak stationarity of the time series and that the fluctuations can be described by a superposition of plane waves with random phases. In this paper we test whether the method can cope with a synthetic signal which is composed of a combination of non-random-phase coherent structures with a mean radius d and a mean separation λ, as well as plane waves with random phase.

  7. Estimating the treatment effect from non-randomized studies: The example of reduced intensity conditioning allogeneic stem cell transplantation in hematological diseases

    Directory of Open Access Journals (Sweden)

    Resche-Rigon Matthieu

    2012-08-01

    Full Text Available Abstract Background In some clinical situations, for which RCT are rare or impossible, the majority of the evidence comes from observational studies, but standard estimations could be biased because they ignore covariates that confound treatment decisions and outcomes. Methods Three observational studies were conducted to assess the benefit of Allo-SCT in hematological malignancies of multiple myeloma, follicular lymphoma and Hodgkin’s disease. Two statistical analyses were performed: the propensity score (PS matching approach and the inverse probability weighting (IPW approach. Results Based on PS-matched samples, a survival benefit in MM patients treated by Allo-SCT, as compared to similar non-allo treated patients, was observed with an HR of death at 0.35 (95%CI: 0.14-0.88. Similar results were observed in HD, 0.23 (0.07-0.80 but not in FL, 1.28 (0.43-3.77. Estimated benefits of Allo-SCT for the original population using IPW were erased in HR for death at 0.72 (0.37-1.39 for MM patients, 0.60 (0.19-1.89 for HD patients, and 2.02 (0.88-4.66 for FL patients. Conclusion Differences in estimated benefits rely on whether the underlying population to which they apply is an ideal randomized experimental population (PS or the original population (IPW. These useful methods should be employed when assessing the effects of innovative treatment in non-randomized experiments.

  8. Laparoscopic Complete Mesocolic Excision versus Open Complete Mesocolic Excision for Transverse Colon Cancer: Long-Term Survival Results of a Prospective Single Centre Non-Randomized Study.

    Science.gov (United States)

    Storli, Kristian Eeg; Eide, Geir Egil

    2016-01-01

    Laparoscopic complete mesocolic excision (CME) used in the treatment of transverse colon cancer has been questioned on the basis of the technical challenges. The aim of this study was to evaluate the medium- and long-term clinical and survival outcomes after laparoscopic and open CME for transverse colon cancer and to compare the 2 approaches. This study was a retrospective non-randomized study of patients with prospectively registered data on open and laparoscopic CME for transverse colon cancer tumour-node-metastasis stages I-III operated on between 2007 and 2014. This was a single-centre study in a community teaching hospital. A total of 56 patients with transverse colon cancer were included, excluding those with tumours in the colonic flexures. The outcome aims were 4-year time to recurrence (TTR) and cancer-specific survival (CSS). Morbidity was also measured. The 4-year TTR was 93.9% in the laparoscopic group and 91.3% in the open group (p = 0.71). The 4-year CSS was 97.0% in the laparoscopic group and 91.3% in the open group (p = 0.42). This was a prospective single-institution study with a small sample size. Results of the study suggest that the laparoscopic CME approach might be the preferred approach for transverse colon cancer, especially regarding its benefits in terms of short-term morbidity, length of stay and oncological outcome. © 2016 S. Karger AG, Basel.

  9. Exceptional gauge groups and quantum theory

    International Nuclear Information System (INIS)

    Horwitz, L.P.; Biedenharn, L.C.

    1979-01-01

    It is shown that a Hilbert space over the real Clifford algebra C 7 provides a mathematical framework, consistent with the structure of the usual quantum mechanical formalism, for models for the unification of weak, electromagnetic and strong interactions utilizing the exceptional Lie groups. In particular, in case no further structure is assumed beyond that of C 7 , the group of automorphisms leaving invariant a minimal subspace acts, in the ideal generated by that subspace, as G 2 , and the subgroup of this group leaving one generating element (e 7 ) fixed acts, in this ideal, as the color gauge group SU(3). A generalized phase algebra AcontainsC 7 is defined by the requirement that quantum mechanical states can be consistently constructed for a theory in which the smallest linear manifolds are closed over the subalgebra C(1,e 7 ) (isomorphic to the complex field) of C 7 . Eight solutions are found for the generalized phase algebra, corresponding (up to an overall sign), in effect, to the use of +- e 7 as imaginary unit in each of four superselection sectors. Operators linear over these alternative forms of imanary unit provide distinct types of ''lepton--quark'' and ''quark--quark'' transitions. The subgroup in A which leaves expectation values of operators linear over A invariant is its unitary subgroup U(4), and is a realization (explicitly constructed) of the U(4) invariance of the complex scalar product. An embedding of the algebraic Hilbert space into the complex space defined over C(1,e 7 ) is shown to lead to a decomposition into ''lepton and ''quark'' superselection subspaces. The color SU(3) subgroup of G 2 coincides with the SU(3) subgroup of the generalized phase U(4) which leaves the ''lepton'' space invariant. The problem of constructing tensor products is studied, and some remarks are made on observability and the role of nonassociativity

  10. A Year of Exceptional Achievements FY 2008

    International Nuclear Information System (INIS)

    Devore, L.; Chrzanowski, P.

    2008-01-01

    2008 highlights: (1) Stockpile Stewardship and Complex Transformation - LLNL achieved scientific breakthroughs that explain some of the key 'unknowns' in nuclear weapons performance and are critical to developing the predictive science needed to ensure the safety, reliability, and security of the U.S. nuclear deterrent without nuclear testing. In addition, the National Ignition Facility (NIF) passed 99 percent completion, an LLNL supercomputer simulation won the 2007 Gordon Bell Prize, and a significant fraction of our inventory of special nuclear material was shipped to other sites in support of complex transformation. (2) National and Global Security - Laboratory researchers delivered insights, technologies, and operational capabilities that are helping to ensure national security and global stability. Of particular note, they developed advanced detection instruments that provide increased speed, accuracy, specificity, and resolution for identifying and characterizing biological, chemical, nuclear, and high-explosive threats. (3) Exceptional Science and Technology - The Laboratory continued its tradition of scientific excellence and technical innovation. LLNL scientists made significant contributions to Nobel Prize-winning work on climate change. LLNL also received three R and D 100 awards and six Nanotech 50 awards, and dozens of Laboratory scientists and engineers were recognized with professional awards. These honors provide valuable confirmation that peers and outside experts recognize the quality of our staff and our work. (4) Enhanced Business and Operations - A major thrust under LLNS is to make the Laboratory more efficient and cost competitive. We achieved roughly $75 million in cost savings for support activities through organizational changes, consolidation of services, improved governance structures and work processes, technology upgrades, and systems shared with Los Alamos National Laboratory. We realized nonlabor cost savings of $23 million. Severe

  11. A Year of Exceptional Achievements FY 2008

    Energy Technology Data Exchange (ETDEWEB)

    devore, L; Chrzanowski, P

    2008-11-06

    2008 highlights: (1) Stockpile Stewardship and Complex Transformation - LLNL achieved scientific breakthroughs that explain some of the key 'unknowns' in nuclear weapons performance and are critical to developing the predictive science needed to ensure the safety, reliability, and security of the U.S. nuclear deterrent without nuclear testing. In addition, the National Ignition Facility (NIF) passed 99 percent completion, an LLNL supercomputer simulation won the 2007 Gordon Bell Prize, and a significant fraction of our inventory of special nuclear material was shipped to other sites in support of complex transformation. (2) National and Global Security - Laboratory researchers delivered insights, technologies, and operational capabilities that are helping to ensure national security and global stability. Of particular note, they developed advanced detection instruments that provide increased speed, accuracy, specificity, and resolution for identifying and characterizing biological, chemical, nuclear, and high-explosive threats. (3) Exceptional Science and Technology - The Laboratory continued its tradition of scientific excellence and technical innovation. LLNL scientists made significant contributions to Nobel Prize-winning work on climate change. LLNL also received three R&D 100 awards and six Nanotech 50 awards, and dozens of Laboratory scientists and engineers were recognized with professional awards. These honors provide valuable confirmation that peers and outside experts recognize the quality of our staff and our work. (4) Enhanced Business and Operations - A major thrust under LLNS is to make the Laboratory more efficient and cost competitive. We achieved roughly $75 million in cost savings for support activities through organizational changes, consolidation of services, improved governance structures and work processes, technology upgrades, and systems shared with Los Alamos National Laboratory. We realized nonlabor cost savings of $23 million

  12. Taxonomic and chemical assessment of exceptionally abundant rock mine biofilm

    Directory of Open Access Journals (Sweden)

    Karolina Tomczyk-Żak

    2017-08-01

    Full Text Available Background An exceptionally thick biofilm covers walls of ancient gold and arsenic Złoty Stok mine (Poland in the apparent absence of organic sources of energy. Methods and Results We have characterized this microbial community using culture-dependent and independent methods. We sequenced amplicons of the 16S rRNA gene obtained using generic primers and additional primers targeted at Archaea and Actinobacteria separately. Also, we have cultured numerous isolates from the biofilm on different media under aerobic and anaerobic conditions. We discovered very high biodiversity, and no single taxonomic group was dominant. The majority of almost 4,000 OTUs were classified above genus level indicating presence of novel species. Elemental analysis, performed using SEM-EDS and X-ray, of biofilm samples showed that carbon, sulphur and oxygen were not evenly distributed in the biofilm and that their presence is highly correlated. However, the distribution of arsenic and iron was more flat, and numerous intrusions of elemental silver and platinum were noted, indicating that microorganisms play a key role in releasing these elements from the rock. Conclusions Altogether, the picture obtained throughout this study shows a very rich, complex and interdependent system of rock biofilm. The chemical heterogeneity of biofilm is a likely explanation as to why this oligotrophic environment is capable of supporting such high microbial diversity.

  13. Gender Diversities

    DEFF Research Database (Denmark)

    Agustin, Lise Rolandsen; Siim, Birte

    2014-01-01

    by non-citizen/citizen and redistribution/recognition divisions. Employing intersectionality as the methodological approach to gender diversities, the article shows how gender and ethnicity are articulated in the policy-making process which led to the adoption of EY 201, the activities undertaken during...

  14. Generational diversity.

    Science.gov (United States)

    Kramer, Linda W

    2010-01-01

    Generational diversity has proven challenges for nurse leaders, and generational values may influence ideas about work and career planning. This article discusses generational gaps, influencing factors and support, and the various generational groups present in today's workplace as well as the consequences of need addressing these issues. The article ends with a discussion of possible solutions.

  15. PLANT DIVERSITY

    Science.gov (United States)

    Habitat change statistics and species-area curves were used to estimate the effects of alternative future scenarios for agriculture on plant diversity in Iowa farmlands. Study areas were two watersheds in central Iowa of about 50 and 90 square kilometers, respectively. Future s...

  16. Une Exception Francaise: Les Grandes Ecoles (A French Exception: The Great Schools).

    Science.gov (United States)

    Kimmel, Alain

    1996-01-01

    Examines the role of exceptional schools in France that have produced famous personages such as Charles de Gaulle and Jean-Paul Sartre. The schools reviewed include L'Ecole Nationale d'Administration, L'Ecole Polytechnique, L'Ecole Normale Superieure, L'Ecole des Hautes Etudes Commerciales, Saint-Cyr, and L'Institut d'Etudes Politiques de Paris.…

  17. Evaluation of an educational "toolbox" for improving nursing staff competence and psychosocial work environment in elderly care: results of a prospective, non-randomized controlled intervention.

    Science.gov (United States)

    Arnetz, J E; Hasson, H

    2007-07-01

    Lack of professional development opportunities among nursing staff is a major concern in elderly care and has been associated with work dissatisfaction and staff turnover. There is a lack of prospective, controlled studies evaluating the effects of educational interventions on nursing competence and work satisfaction. The aim of this study was to evaluate the possible effects of an educational "toolbox" intervention on nursing staff ratings of their competence, psychosocial work environment and overall work satisfaction. The study was a prospective, non-randomized, controlled intervention. Nursing staff in two municipal elderly care organizations in western Sweden. In an initial questionnaire survey, nursing staff in the intervention municipality described several areas in which they felt a need for competence development. Measurement instruments and educational materials for improving staff knowledge and work practices were then collated by researchers and managers in a "toolbox." Nursing staff ratings of their competence and work were measured pre and post-intervention by questionnaire. Staff ratings in the intervention municipality were compared to staff ratings in the reference municipality, where no toolbox was introduced. Nursing staff ratings of their competence and psychosocial work environment, including overall work satisfaction, improved significantly over time in the intervention municipality, compared to the reference group. Both competence and work environment ratings were largely unchanged among reference municipality staff. Multivariate analysis revealed a significant interaction effect between municipalities over time for nursing staff ratings of participation, leadership, performance feedback and skills' development. Staff ratings for these four scales improved significantly in the intervention municipality as compared to the reference municipality. Compared to a reference municipality, nursing staff ratings of their competence and the

  18. Lifetime health effects and medical costs of integrated stroke services - a non-randomized controlled cluster-trial based life table approach

    Directory of Open Access Journals (Sweden)

    Dirks Maaike

    2010-11-01

    Full Text Available Abstract Background Economic evaluation of stroke services indicates that such services may lead to improved quality of life at affordable cost. The present study assesses lifetime health impact and cost consequences of stroke in an integrated service setting. Methods The EDISSE study is a prospective non-randomized controlled cluster trial that compared stroke services (n = 151 patients to usual care (n = 187 patients. Health status and cost trial-data were entered in multi-dimensional stroke life-tables. The tables distinguish four levels of disability which are defined by the modified Rankin scale. Quality-of-life scores (EuroQoL-5D, transition and survival probabilities are based on concurrent Dutch follow-up studies. Outcomes are quality-adjusted life years lived and lifetime medical cost by disability category. An economic analysis compares outcomes from a successful stroke service to usual care, by bootstrapping individual costs and effects data from patients in each arm. Results Lifetime costs and QALYs after stroke depend on age-of-onset of first-ever stroke. Lifetime QALYs after stroke are 2.42 (90% CI - 0.49 - 2.75 for male patients in usual care and 2.75 (-0.61; 6.26 for females. Lifetime costs for men in the usual care setting are €39,335 (15,951; 79,837 and €42,944 (14,081; 95,944 for women. A comparison with the stroke service results in an ICER of €11,685 saved per QALY gained (€14,211 and €7,745 for men and women respectively. This stroke service is with 90% certainty cost-effective. Conclusions Our analysis shows the potential of large health benefits and cost savings of stroke services, taking a lifetime perspective, also in other European settings.

  19. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR and its effects on blood NAD+ levels in healthy volunteers.

    Directory of Open Access Journals (Sweden)

    Sophia E Airhart

    Full Text Available The co-primary objectives of this study were to determine the human pharmacokinetics (PK of oral NR and the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+ levels.Though mitochondrial dysfunction plays a critical role in the development and progression of heart failure, no mitochondria-targeted therapies have been translated into clinical practice. Recent murine studies have reported associations between imbalances in the NADH/NAD+ ratio with mitochondrial dysfunction in multiple tissues, including myocardium. Moreover, an NAD+ precursor, nicotinamide mononucleotide, improved cardiac function, while another NAD+ precursor, nicotinamide riboside (NR, improved mitochondrial function in muscle, liver and brown adipose. Thus, PK studies of NR in humans is critical for future clinical trials.In this non-randomized, open-label PK study of 8 healthy volunteers, 250 mg NR was orally administered on Days 1 and 2, then uptitrated to peak dose of 1000 mg twice daily on Days 7 and 8. On the morning of Day 9, subjects completed a 24-hour PK study after receiving 1000 mg NR at t = 0. Whole-blood levels of NR, clinical blood chemistry, and NAD+ levels were analyzed.Oral NR was well tolerated with no adverse events. Significant increases comparing baseline to mean concentrations at steady state (Cave,ss were observed for both NR (p = 0.03 and NAD+ (p = 0.001; the latter increased by 100%. Absolute changes from baseline to Day 9 in NR and NAD+ levels correlated highly (R2 = 0.72, p = 0.008.Because NR increases circulating NAD+ in humans, NR may have potential as a therapy in patients with mitochondrial dysfunction due to genetic and/or acquired diseases.

  20. A prospective, non-randomized phase II trial of Trastuzumab and Capecitabine in patients with HER2 expressing metastasized pancreatic cancer

    Directory of Open Access Journals (Sweden)

    Endlicher Esther

    2009-01-01

    Full Text Available Abstract Background Pancreatic cancer is the fourth most common cause of cancer related death in Western countries. Advantages in surgical techniques, radiation and chemotherapy had almost no impact on the long term survival of affected patients. Therefore, the need for better treatment strategies is urgent. HER2, a receptor tyrosine kinase of the EGFR family, involved in signal transduction pathways leading to cell growth and differentiation is overexpressed in a number of cancers, including breast and pancreatic cancer. While in breast cancer HER2 has already been successfully used as a treatment target, there are only limited data evaluating the effects of inhibiting HER2 tyrosine kinases in patients with pancreatic cancer. Methods Here we report the design of a prospective, non-randomized multi-centered Phase II clinical study evaluating the effects of the Fluoropyrimidine-carbamate Capecitabine (Xeloda ® and the monoclonal anti-HER2 antibody Trastuzumab (Herceptin® in patients with non-resectable, HER2 overexpressing pancreatic cancer. Patients eligible for the study will receive Trastuzumab infusions on day 1, 8 and 15 concomitant to the oral intake of Capecitabine from day 1 to day 14 of each three week cylce. Cycles will be repeated until tumor progression. A total of 37 patients will be enrolled with an interim analysis after 23 patients. Discussion Primary end point of the study is to determine the progression free survival after 12 weeks of bimodal treatment with the chemotherapeutic agent Capecitabine and the anti-HER2 antibody Trastuzumab. Secondary end points include patient's survival, toxicity analysis, quality of life, the correlation of HER2 overexpression and clinical response to Trastuzumab treatment and, finally, the correlation of CA19-9 plasma levels and progression free intervals.

  1. Effectiveness of a peer-led HIV prevention intervention in secondary schools in Rwanda: results from a non-randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Michielsen Kristien

    2012-09-01

    Full Text Available Abstract Background While the HIV epidemic is levelling off in sub-Saharan Africa, it remains at an unacceptably high level. Young people aged 15-24 years remain particularly vulnerable, resulting in a regional HIV prevalence of 1.4% in young men and 3.3% in young women. This study assesses the effectiveness of a peer-led HIV prevention intervention in secondary schools in Rwanda on young people’s sexual behavior, HIV knowledge and attitudes. Methods In a non-randomized longitudinal controlled trial, fourteen schools were selected in two neighboring districts in Rwanda Bugesera (intervention and Rwamagana (control. Students (n = 1950 in eight intervention and six control schools participated in three surveys (baseline, six and twelve months in the intervention. Analysis was done using linear and logistic regression using generalized estimation equations adjusted for propensity score. Results The overall retention rate was 72%. Time trends in sexual risk behavior (being sexually active, sex in last six months, condom use at last sex were not significantly different in students from intervention and control schools, nor was the intervention associated with increased knowledge, perceived severity or perceived susceptibility. It did significantly reduce reported stigma. Conclusions Analyzing this and other interventions, we identified several reasons for the observed limited effectiveness of peer education: 1 intervention activities (spreading information are not tuned to objectives (changing behavior; 2 young people prefer receiving HIV information from other sources than peers; 3 outcome indicators are not adequate and the context of the relationship in which sex occurs and the context in which sex occurs is ignored. Effectiveness of peer education may increase through integration in holistic interventions and redefining peer educators’ role as focal points for sensitization and referral to experts and services. Finally, we argue that a

  2. An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.

    Science.gov (United States)

    Airhart, Sophia E; Shireman, Laura M; Risler, Linda J; Anderson, Gail D; Nagana Gowda, G A; Raftery, Daniel; Tian, Rong; Shen, Danny D; O'Brien, Kevin D

    2017-01-01

    The co-primary objectives of this study were to determine the human pharmacokinetics (PK) of oral NR and the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+) levels. Though mitochondrial dysfunction plays a critical role in the development and progression of heart failure, no mitochondria-targeted therapies have been translated into clinical practice. Recent murine studies have reported associations between imbalances in the NADH/NAD+ ratio with mitochondrial dysfunction in multiple tissues, including myocardium. Moreover, an NAD+ precursor, nicotinamide mononucleotide, improved cardiac function, while another NAD+ precursor, nicotinamide riboside (NR), improved mitochondrial function in muscle, liver and brown adipose. Thus, PK studies of NR in humans is critical for future clinical trials. In this non-randomized, open-label PK study of 8 healthy volunteers, 250 mg NR was orally administered on Days 1 and 2, then uptitrated to peak dose of 1000 mg twice daily on Days 7 and 8. On the morning of Day 9, subjects completed a 24-hour PK study after receiving 1000 mg NR at t = 0. Whole-blood levels of NR, clinical blood chemistry, and NAD+ levels were analyzed. Oral NR was well tolerated with no adverse events. Significant increases comparing baseline to mean concentrations at steady state (Cave,ss) were observed for both NR (p = 0.03) and NAD+ (p = 0.001); the latter increased by 100%. Absolute changes from baseline to Day 9 in NR and NAD+ levels correlated highly (R2 = 0.72, p = 0.008). Because NR increases circulating NAD+ in humans, NR may have potential as a therapy in patients with mitochondrial dysfunction due to genetic and/or acquired diseases.

  3. Increasing capacity to deliver diabetes self-management education: results of the DESMOND lay educator non-randomized controlled equivalence trial.

    Science.gov (United States)

    Carey, M E; Mandalia, P K; Daly, H; Gray, L J; Hale, R; Martin Stacey, L; Taub, N; Skinner, T C; Stone, M; Heller, S; Khunti, K; Davies, M J

    2014-11-01

    To develop and test a format of delivery of diabetes self-management education by paired professional and lay educators. We conducted an equivalence trial with non-randomized participant allocation to a Diabetes Education and Self Management for Ongoing and Newly Diagnosed Type 2 diabetes (DESMOND) course, delivered in the standard format by two trained healthcare professional educators (to the control group) or by one trained lay educator and one professional educator (to the intervention group). A total of 260 people with Type 2 diabetes diagnosed within the previous 12 months were referred for self-management education as part of routine care and attended either a control or intervention format DESMOND course. The primary outcome measure was change in illness coherence score (derived from the Diabetes Illness Perception Questionnaire-Revised) between baseline and 4 months after attending education sessions. Secondary outcome measures included change in HbA1c level. The trial was conducted in four primary care organizations across England and Scotland. The 95% CI for the between-group difference in positive change in coherence scores was within the pre-set limits of equivalence (difference = 0.22, 95% CI 1.07 to 1.52). Equivalent changes related to secondary outcome measures were also observed, including equivalent reductions in HbA1c levels. Diabetes education delivered jointly by a trained lay person and a healthcare professional educator with the same educator role can provide equivalent patient benefits. This could provide a method that increases capacity, maintains quality and is cost-effective, while increasing access to self-management education. © 2014 The Authors. Diabetic Medicine © 2014 Diabetes UK.

  4. Effect of cognitive behavioral group therapy for recovery of self-esteem on community-living individuals with mental illness: Non-randomized controlled trial.

    Science.gov (United States)

    Kunikata, Hiroko; Yoshinaga, Naoki; Nakajima, Kazuo

    2016-10-01

    The aim of this study was to examine over a 12-month post-intervention period whether the participation of community-living individuals with mental illness in cognitive behavioral group therapy for recovery of self-esteem (CBGTRS) resulted in improved outcomes. This was a non-randomized controlled trial. The participants were persons with mental illness who resided in communities in the Chugoku region of Japan. In total, 41 were assigned to an experimental group (CBGTRS intervention, 12 group sessions), and 21 to a control group. Outcome indices (self-esteem, moods, cognition, subjective well-being, psychiatric symptoms) were measured for the experimental group prior to intervention (T0), immediately post-intervention (T1), and at 3 (T2) and 12 (T3) months post-intervention. The control group was measured at the same intervals. For the experimental group, self-esteem scores at T1, T2, and T3 were significantly higher than at T0. Moods and cognition scores remained significantly low until T2. Scores for Inadequate Mental Mastery in the subjective well-being index had not decreased by T3. Confidence in Coping remained significantly high until T2. Psychiatric symptoms scores at T0, T1, T2, and T3 were significantly lower than at T0. The means and standard errors for self-esteem and Inadequate Mental Mastery increased until T3, and those for Tension-Anxiety, Depression-Dejection, and Confusion decreased until T2. From within-group trends and between-group differences in self-esteem, we conclude that CBGTRS may have a relatively long-term effect on self-esteem recovery. T2 is the turning point for moods and cognition; thus, follow-up is needed 3 months following the initial program. © 2016 The Authors. Psychiatry and Clinical Neurosciences © 2016 Japanese Society of Psychiatry and Neurology.

  5. Two-stage revision surgery with preformed spacers and cementless implants for septic hip arthritis: a prospective, non-randomized cohort study

    Directory of Open Access Journals (Sweden)

    Logoluso Nicola

    2011-05-01

    Full Text Available Abstract Background Outcome data on two-stage revision surgery for deep infection after septic hip arthritis are limited and inconsistent. This study presents the medium-term results of a new, standardized two-stage arthroplasty with preformed hip spacers and cementless implants in a consecutive series of adult patients with septic arthritis of the hip treated according to a same protocol. Methods Nineteen patients (20 hips were enrolled in this prospective, non-randomized cohort study between 2000 and 2008. The first stage comprised femoral head resection, debridement, and insertion of a preformed, commercially available, antibiotic-loaded cement hip spacer. After eradication of infection, a cementless total hip arthroplasty was implanted in the second stage. Patients were assessed for infection recurrence, pain (visual analog scale [VAS] and hip joint function (Harris Hip score. Results The mean time between first diagnosis of infection and revision surgery was 5.8 ± 9.0 months; the average duration of follow up was 56.6 (range, 24 - 104 months; all 20 hips were successfully converted to prosthesis an average 22 ± 5.1 weeks after spacer implantation. Reinfection after total hip joint replacement occurred in 1 patient. The mean VAS pain score improved from 48 (range, 35 - 84 pre-operatively to 18 (range, 0 - 38 prior to spacer removal and to 8 (range, 0 - 15 at the last follow-up assessment after prosthesis implantation. The average Harris Hip score improved from 27.5 before surgery to 61.8 between the two stages to 92.3 at the final follow-up assessment. Conclusions Satisfactory outcomes can be obtained with two-stage revision hip arthroplasty using preformed spacers and cementless implants for prosthetic hip joint infections of various etiologies.

  6. "No admittance except on business" 

    Directory of Open Access Journals (Sweden)

    Mathilde Bourrier

    2011-04-01

     sociologie embarquée », soit s’en dégager radicalement.“No admittance except on business”. Issues in negotiating entry into organisationsThis article has a history. The first reason for wanting to write it was linked to the development in 2007 of a master course in sociology on the conditions associated with being able to enter organisations. To my great surprise, and in spite of my efforts during the preparation of the course, I found few texts which discussed real entry conditions. This article reflects then this disappointment. The second reason concerns repeated observations of the hardening conditions in relation with studies undertaken within organisations, whether in France or the United States. Reports I have received confirm my observations that the field of high risk organisations has become particularly more and more difficult for young researchers or doctoral students to freely organize their work. Paradoxically, whilst more efforts are undertaken so that sociologists (amongst others have access to risk industries, researchers are confronted with conditions that are often rigid and hardly generous. As for the issues themselves that are studied, they are very aligned with the industrials’ own managerial questions. Ethnographic studies by immersion are abandoned in favour of action-research, in form de theses obliged, at the end of the day, to make propositions for improvements and recommendations about management tools. I have a feeling that what is happening in high-risk organisations is also the case for the sociology of organisations in general. In the first part of this article, I propose a partial revue of the way that the sociology of organisations has treated the question of entering into organisations. I will reflect on why there are so few works devoted to this question and on what the consequences may well be for the field itself. Secondly, I will examine the possibilities offered today as well as the efforts to make in order to, either, resolutely

  7. 45 CFR 670.5 - Exception in extraordinary circumstances.

    Science.gov (United States)

    2010-10-01

    ... involving the safety of human life or of ships, aircraft, or equipment or facilities of high value, or the... FOUNDATION CONSERVATION OF ANTARCTIC ANIMALS AND PLANTS Prohibited Acts, Exceptions § 670.5 Exception in...

  8. Detecting and explaining business exceptions for risk assessment

    NARCIS (Netherlands)

    Liu, L.; Daniëls, H.A.M.; Hofman, W.; Hammoudi, S.; Maciaszek, L.; Cordeiro, J.; Dietz, J.

    2013-01-01

    Systematic risk analysis can be based on causal analysis of business exceptions. In this paper we describe the concepts of automatic analysis for the exceptional patterns which are hidden in a large set of business data. These exceptions are interesting to be investigated further for their causes

  9. Execution Constraint Verification of Exception Handling on UML Sequence Diagrams

    NARCIS (Netherlands)

    Ciraci, S.; Sözer, Hasan; Aksit, Mehmet; Havinga, W.K.

    2011-01-01

    Exception handling alters the control flow of the program. As such, errors introduced in exception handling code may influence the overall program in undesired ways. To detect such errors early and thereby decrease the programming costs, it is worthwhile to consider exception handling at design

  10. Diverse Multilateralism

    DEFF Research Database (Denmark)

    Wuthnow, Joel; Li, Xin; Qi, Lingling

    2012-01-01

    This article addresses Chinas multilateral diplomacy by identifying four distinct strategies: watching, engaging, circumventing, and shaping. The typology builds on two literatures: power transition theory, and the more recent “assertiveness” discourse in the West. Drawing from a range of cases...... in both the economic and security domains, the article argues that China’s multilateralism is diverse, and that it cannot be un-problematically characterized as either status-quo or revisionist in nature. However, the general trend appears to be towards engagement, but with an assertive tact as China...

  11. Doing Diversity

    DEFF Research Database (Denmark)

    Just, Sine Nørholm; Christiansen, Tanja Juul

    2012-01-01

    Questions of agency in text–audience relations are less studied than other aspects of rhetorical agency. We suggest conceptualizing and analyzing the relationship between texts and audiences from the perspective of performativity, as it has been developed by Judith Butler. Thus, we argue that texts...... invite audiences to take up subject positions, understood as combinations of identity and agency. Danish diversity management rhetoric functions as an illustrative example; in analyzing this type of rhetoric we show how subjects are called into restrained positions of similarity/difference and thereby...

  12. A psycho-educational HIV/STI prevention intervention for internally displaced women in Leogane, Haiti: results from a non-randomized cohort pilot study.

    Science.gov (United States)

    Logie, Carmen H; Daniel, CarolAnn; Newman, Peter A; Weaver, James; Loutfy, Mona R

    2014-01-01

    Little evidence exists regarding efficacious HIV and sexually transmitted infections (STI) prevention interventions with internally displaced populations. Internally displaced women are at elevated risk for HIV/STI due to limited access to health services, heightened poverty and social network breakdown. The FASY (Famn an Aksyon Pou Sante' Yo) (Women Taking Action For Their Health) study examined the effectiveness of a peer health worker (PHW) delivered psycho-educational HIV/STI pilot study with internally displaced women in Leogane, Haiti. This was a non-randomized cohort pilot study. Participants completed a computer-assisted pre-test programmed on Android tablet PCs followed by an HIV/STI educational video-based session and a 6-week psycho-educational group program of weekly meetings. Participants completed a post-test upon completion of group sessions. The primary outcome was HIV knowledge; our pre-specified index of clinically significant change was an effect size of 0.30. Secondary outcomes included: STI knowledge, condom use, social support, resilient coping, depression and relationship control. We used mixed-effects regression to calculate mean outcome pre-post score change. This study was registered (clinicaltrials.gov, NCT01492829). Between January 1-April 30, 2012 we assigned 200 participants to the study. The majority of participants (n = 176, 88%) completed the study and were followed up at 8 weeks, finishing April 30, 2012. Adjusted for socio-demographic characteristics, HIV knowledge (β = 4.81; 95% CI 4.36-5.26), STI knowledge (β = 0.84; 95% CI 0.70-0.99), condom use (AOR = 4.05, 95% CI 1.86-8.83), and depression (β = -0.63, 95% CI -0.88--0.39) scores showed statistically significant change post-intervention (pHaiti. Pilot studies are an important approach to understand feasibility and scientific impacts of HIV prevention strategies in disaster contexts. Study results may inform HIV prevention interventions among internally displaced women in

  13. TP53 status and taxane-platinum versus platinum-based therapy in ovarian cancer patients: A non-randomized retrospective study

    Directory of Open Access Journals (Sweden)

    Markowska Janina

    2008-01-01

    Full Text Available Abstract Background Taxane-platinum therapy (TP has replaced platinum-based therapy (PC or PAC, DNA damaging chemotherapy in the postoperative treatment of ovarian cancer patients; however, it is not always effective. TP53 protein plays a differential role in response to DNA-damaging agents and taxanes. We sought to define profiles of patients who benefit the most from TP and also of those who can be treated with PC. Methods We compared the effectiveness of PC/PAC (n = 253 and TP (n = 199 with respect to tumor TP53 accumulation in ovarian cancer patients with FIGO stage IIB-IV disease; this was a non-randomized retrospective study. Immunohistochemical analysis was performed on 452 archival tumors; univariate and multivariate analysis by the Cox's and logistic regression models was performed in all patients and in subgroups with [TP53(+] and without TP53 accumulation [TP53(-]. Results The advantage of taxane-platinum therapy over platinum-based therapy was seen in the TP53(+, and not in the TP53(- group. In the TP53(+ group taxane-platinum therapy enhanced the probability of complete remission (p = .018, platinum sensitivity (p = .014, platinum highly sensitive response (p = .038 and longer survival (OS, p = .008. Poor tumor differentiation diminished the advantage from taxane-platinum therapy in the TP53(+ group. In the TP53(- group PC/PAC was at least equally efficient as taxane-platinum therapy and it enhanced the chance of platinum highly sensitive response (p = .010. However, in the TP53(- group taxane-platinum therapy possibly diminished the risk of death in patients over 53 yrs (p = .077. Among factors that positively interacted with taxane-platinum therapy in some analyses were endometrioid and clear cell type, FIGO III stage, bulky residual tumor, more advanced age of patient and moderate tumor differentiation. Conclusion Our results suggest that taxane-platinum therapy is particularly justified in patients with TP53(+ tumors or older

  14. Evaluation of an advanced pressure ulcer management protocol followed by trained wound, ostomy, and continence nurses: a non-randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Kaitani T

    2015-02-01

    Full Text Available Toshiko Kaitani,1 Gojiro Nakagami,2 Junko Sugama,3 Masahiro Tachi,4 Yutaka Matsuyama,5 Yoshiki Miyachi,6 Takashi Nagase,2 Yukie Takemura,7 Hiromi Sanada2 1School of Nursing, Sapporo City University, Hokkaido, Japan; 2Department of Gerontological Nursing/Wound Care Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; 3Department of Clinical Nursing, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan; 4Department of Plastic Surgery, Tohoku University Graduate School of Medicine, Miyagi, Japan; 5Department of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; 6Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; 7Department of Nursing, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan Aims and objectives: We investigated the effectiveness and safety of an advanced pressure ulcer (PU management protocol comprising 1 ultrasonography to assess the deep tissue, 2 use of a non-contact thermometer to detect critical colonization, 3 conservative sharp debridement, 4 dressing selection, 5 negative pressure wound therapy, and 6 vibration therapy in comparison with those of a conventional approach. Each protocol was followed by trained wound, ostomy, and continence nurses (WOCNs. Background: At present, there is no systematic PU management protocol for nurses that includes appropriate assessment and intervention techniques for deep tissue injury and critical colonization. In Japan, there is no such protocol that the nurses can follow without a physician’s orders. Design and methods: This was a prospective non-randomized controlled trial. Over a 3-week period, we evaluated the effectiveness of an advanced protocol by comparing the PU severity and healing on the basis of the DESIGN-R scale and presence of patients' discomfort. We recruited ten WOCNs to follow

  15. A psycho-educational HIV/STI prevention intervention for internally displaced women in Leogane, Haiti: results from a non-randomized cohort pilot study.

    Directory of Open Access Journals (Sweden)

    Carmen H Logie

    Full Text Available Little evidence exists regarding efficacious HIV and sexually transmitted infections (STI prevention interventions with internally displaced populations. Internally displaced women are at elevated risk for HIV/STI due to limited access to health services, heightened poverty and social network breakdown. The FASY (Famn an Aksyon Pou Sante' Yo (Women Taking Action For Their Health study examined the effectiveness of a peer health worker (PHW delivered psycho-educational HIV/STI pilot study with internally displaced women in Leogane, Haiti.This was a non-randomized cohort pilot study. Participants completed a computer-assisted pre-test programmed on Android tablet PCs followed by an HIV/STI educational video-based session and a 6-week psycho-educational group program of weekly meetings. Participants completed a post-test upon completion of group sessions. The primary outcome was HIV knowledge; our pre-specified index of clinically significant change was an effect size of 0.30. Secondary outcomes included: STI knowledge, condom use, social support, resilient coping, depression and relationship control. We used mixed-effects regression to calculate mean outcome pre-post score change. This study was registered (clinicaltrials.gov, NCT01492829.Between January 1-April 30, 2012 we assigned 200 participants to the study. The majority of participants (n = 176, 88% completed the study and were followed up at 8 weeks, finishing April 30, 2012. Adjusted for socio-demographic characteristics, HIV knowledge (β = 4.81; 95% CI 4.36-5.26, STI knowledge (β = 0.84; 95% CI 0.70-0.99, condom use (AOR = 4.05, 95% CI 1.86-8.83, and depression (β = -0.63, 95% CI -0.88--0.39 scores showed statistically significant change post-intervention (p<0.05.This pilot study evaluated a PHW psycho-educational HIV/STI prevention intervention among internally displaced women in post-earthquake Haiti. Pilot studies are an important approach to understand feasibility and scientific

  16. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Science.gov (United States)

    2010-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... the Federal Power Act, at which non-Federal hydroelectric development is permissible; or (2) An...

  17. Exposing diversity

    DEFF Research Database (Denmark)

    Nørtoft, Kamilla; Nordentoft, Helle Merete

    professionals´ meetings with patients and relatives. In the paper we draw data from focus group discussions with interdisciplinary groups of health care professionals working in the area of care for older people. The video narratives used to initiate discussions are developed through ethnographic fieldwork...... in the homes of older people and in pedagogical institutions targeting older people. In the paper we look at the potentials and challenges in working with ethnographic video narratives as a pedagogical tool. Our findings indicate that the use of video narratives has the potential to expose the diversity...... focus on their own professional discipline and its tasks 2) stimulates collaborative learning when they discuss their different interpretations of the ethnographic video narratives and achieve a deeper understanding of each other’s work and their clients’ lifeworlds, which might lead to a better...

  18. Exceptions to the Stark law: practical considerations for surgeons.

    Science.gov (United States)

    Satiani, Bhagwan

    2006-03-01

    The purpose of this study was to provide an understanding of the applicable legislative exceptions to prohibitions under the Stark law, which governs common legitimate business relationships in surgical practice. Stark I and II prohibits all referrals (and claims) for the provision of designated health services for federal reimbursement if a physician or immediate family member has any financial relationship with the entity. Regardless of intent (unlike the antikickback statute), any financial relationship is illegal unless specifically excepted by statute. These exceptions are relevant to ownership, compensation arrangements, or both. The most important ones relevant to surgeons are as follows: physician service exception (services rendered in an intragroup referral); in-office ancillary services exception (office-based vascular laboratory); the whole hospital exception (ownership interest in a hospital or department); lease exception (conditions that must be met for a lease not to be considered illegal); bona fide employment exception (important to academic medical centers); personal services arrangement exception (vascular laboratory medical directorship); physician incentive plans exception (if volume or value of referrals are an issue); hospital-affiliated group practice exception (physician services billed by a hospital); recruitment arrangement exception (inducements by hospitals to relocate); items/services exception (transcription services purchased from a hospital); fair market value exception (covers services provided to health care entities); indirect compensation arrangements (dealings between a hospital and entity owned by physicians); and academic medical centers exception (new phase II rules broaden the definition of academic medical centers and ease the requirement that practice plans be tax-exempt organizations, among other changes. Although expert legal advice is required for navigation through the maze of Stark laws, it is incumbent on surgeons

  19. Is the alpha-beta ratio of prostate cancer really low? A prospective, non-randomized trial comparing standard and hyperfractionated conformal radiation therapy

    International Nuclear Information System (INIS)

    Valdagni, Riccardo; Italia, Corrado; Montanaro, Paolo; Lanceni, Angelo; Lattuada, Paola; Magnani, Tiziana; Fiorino, Claudio; Nahum, Alan

    2005-01-01

    Background and purpose: The objectives of the current study were to compare genito-urinary (GU) and gastro-intestinal (GI) toxicities as well as biochemical control (bRFS) in prostate cancer, utilizing conventional (2.0 Gy daily) (STD) or hyperfractionated (HFX) conformal irradiation (CRT). HFX (1.2 Gy BID) was chosen as a radiobiological method to try to reduce long term sequelae without compromising local control. Patients and methods: Three-hundred-and-seventy consecutive patients (pts) entered this prospective, non-randomized trial in the period January 1993-January 2003; 209 were treated with STD and 161 with HFX CRT. All were evaluable for acute toxicity analysis, 179 (STD) and 151 pts (HFX) being evaluable for late sequelae and bRFS analyses. Pt characteristics were not statistically different in the two groups. CRT consisted of a 4-field technique for prostate and/or pelvic nodes and a 5-field boost with rectal shielding. Median doses were 74 and 79.2 Gy for STD and HFX patients respectively, the latter dose being isoeffective for tumour control assuming α/β=10 (EQD 2 =73.9 Gy). Median follow-up was 29.4 months (25.2 mos for STD; 37.7 mos for HFX; P<0.01). The two regimens were compared in terms of acute and late GU and GI toxicities and 5-year bRFS by univariate and multivariate analyses. Results: Acute grade≥2 GU toxicity was higher in the STD group (48.6% versus 37.3% in HFX, P=0.03), while no significant difference was found for acute GI toxicity. Late grade≥2 GU and GI toxicities were lower in the HFX group (5-year actuarial rate: GU: 10.1% versus 20.3%, P=0.05; GI: 6.0% versus 10.6%, P=0.18). Five-year bRFS were 70% (±13.8%, 95% CI) and 82.6% (±7.2%) for STD and HFX, respectively (P=0.44); a trend favouring HFX was found in the subgroup of pts who did not receive hormonal therapy (5-year bRFS: 85.9%±12.4% versus 63.9%±23.8%, P=0.15). Multivariate analysis revealed only risk groups and age statistically related to bRFS but not fractionation

  20. Survey of serum concentrations of dioxins, furans, and coplanar polychlorinated biphenyls in a small non-random sample of U.S. residents

    Energy Technology Data Exchange (ETDEWEB)

    Grassman, J. [Brooklyn Coll. CUNY, Health and Nutrition Sciences, Brooklyn, New York, NY (United States); Patterson, D.G. Jr.; Needham, L.L. [National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA (United States); Spencer, D.L.; Masten, S.A. [Environmental Toxicology Program, National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States)

    2004-09-15

    This cross sectional assessment of serum dioxin concentrations was conducted as part of a larger study to examine the relationship between dioxin exposure and gene expression in peripheral blood mononuclear cells. Recent reports indicate that environmental levels of dioxins have declined since the mid-1980's. Except for the recent National Health and Nutrition Examination Survey (NHANES), there has been little systematic surveillance of serum dioxins levels in the US general population. Here, we report the serum concentrations of 22 congeners of dioxins and dioxin-like compounds and their relationship with age, sex, smoking, and meat consumption.

  1. Teaching Diversity

    Directory of Open Access Journals (Sweden)

    Kay Young McChesney

    2015-10-01

    Full Text Available This article is targeted to faculty teaching race and ethnicity, racism, diversity, and multicultural courses. Many students equate race with skin color. The premise of this article is that to teach students about the social construction of race, teachers must first know enough science to teach students that race is not biological. This article examines the biology of race by showing how advances in DNA sequencing led to genetics research that supports arguments that race is not biological. DNA comparisons show that all human populations living today are one species that came from Africa. The article explains the migration of humans out of Africa about 60,000 years ago and how they populated Australia, then Asia, Europe, and the Americas. The article shows how recent research maps the timing of the migration and admixture of specific population groups into Europe and India. The article shows how a mutation in one nucleotide can result in a trait like blue eyes, or Hemoglobin S (which confers resistance to malaria, which can be subject to evolution through natural selection. DNA comparisons show how natural selection shaped the genetics of human skin color to adapt to less UV light in the northern latitudes of Europe and Asia. The article shows that there is no relation between skin color or other “racial” characteristics and complex traits like intelligence. The science in this article will help teachers explain that as race is not biological, race is socially constructed and culturally enacted.

  2. 28 CFR 66.6 - Additions and exceptions.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Additions and exceptions. 66.6 Section 66.6 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) UNIFORM ADMINISTRATIVE REQUIREMENTS FOR... additional administrative requirements except in codified regulations published in the Federal Register. (b...

  3. 49 CFR 173.3 - Packaging and exceptions.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Packaging and exceptions. 173.3 Section 173.3... SHIPMENTS AND PACKAGINGS General § 173.3 Packaging and exceptions. (a) The packaging of hazardous materials.... standard packaging must be open to inspection by a representative of the Department. (b) The regulations...

  4. Designing Inclusive Learning for Twice Exceptional Students in Minecraft

    Science.gov (United States)

    O'Sullivan, Muireann; Robb, Nigel; Howell, Stephen; Marshall, Kevin; Goodman, Lizbeth

    2017-01-01

    Twice exceptional learners are intellectually or creatively gifted yet also experience one or more learning difficulties. These students face a unique set of challenges in educational settings. Recommended strategies for accommodating twice exceptional learners focus on--among other things--(1) providing freedom and variety, so that students can…

  5. Cultural Considerations for Twice-Exceptional Children from Asian Families

    Science.gov (United States)

    Park, Soeun

    2015-01-01

    Since the term twice-exceptional has been entered to the field of gifted education, many studies have investigated the population of students who possess both giftedness and disabilities. It has been shown that there are some challenges to recognizing twice-exceptional children due to current screening and identification process. For this reason,…

  6. Parents vs. Theorists: Dealing with the Exceptionally Gifted.

    Science.gov (United States)

    Tolan, Stephanie S.

    1992-01-01

    This paper explores the fundamental rift between parents raising exceptionally gifted children and theorists who dismiss this population as "statistically insignificant." The role of intelligence tests in identifying the highly unusual mind is examined. The paper concludes that exceptionally gifted children are suffering intellectual…

  7. 21 CFR 1302.03 - Symbol required; exceptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Symbol required; exceptions. 1302.03 Section 1302... REQUIREMENTS FOR CONTROLLED SUBSTANCES § 1302.03 Symbol required; exceptions. (a) Each commercial container of... § 1308.31 of this chapter) shall have printed on the label the symbol designating the schedule in which...

  8. 75 FR 23288 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2010-05-03

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... Exceptional Children (Advisory Board) will hold its next meeting in Old Town, Maine. The purpose of the... Indian children with disabilities. DATES: The Advisory Board will meet on Monday, May 17, 2010, from 8:30...

  9. 77 FR 16062 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2012-03-19

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... Individuals with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  10. 77 FR 28897 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... Individuals with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  11. 76 FR 17965 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2011-03-31

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... Individuals with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  12. 77 FR 70807 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2012-11-27

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  13. 78 FR 42105 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2013-07-15

    ....97C22214.001] Advisory Board for Exceptional Children AGENCY: Bureau of Indian Affairs, Interior. ACTION... for Exceptional Children (Advisory Board) will hold its next meeting in Albuquerque, New Mexico. The... (IDEA) for Indian children with disabilities. DATES: The Advisory Board will meet on Thursday, July 18...

  14. 75 FR 82410 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2010-12-30

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... Individuals with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  15. 76 FR 40929 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2011-07-12

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  16. 77 FR 47873 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2012-08-10

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  17. 75 FR 53334 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2010-08-31

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of meeting; correction. SUMMARY: The Bureau of Indian... Advisory Board for Exceptional Children (Advisory Board) will hold its next meeting in Washington, DC. The...

  18. 75 FR 50780 - Advisory Board for Exceptional Children

    Science.gov (United States)

    2010-08-17

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Advisory Board for Exceptional Children AGENCY... (BIE) is announcing that the Advisory Board for Exceptional Children (Advisory Board) will hold its... with Disabilities Education Act of 2004 (IDEA) for Indian children with disabilities. DATES: The...

  19. 29 CFR 1606.3 - The national security exception.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false The national security exception. 1606.3 Section 1606.3... DISCRIMINATION BECAUSE OF NATIONAL ORIGIN § 1606.3 The national security exception. It is not an unlawful employment practice to deny employment opportunities to any individual who does not fulfill the national...

  20. 14 CFR 399.21 - Charter exemptions (except military).

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Charter exemptions (except military). 399.21 Section 399.21 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION... Authority § 399.21 Charter exemptions (except military). In deciding applications for exemptions from...

  1. 16 CFR 1101.42 - Imminent hazard exception.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Imminent hazard exception. 1101.42 Section 1101.42 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS... court. Once the exception applies, information may be disclosed to the public while the proceeding is...

  2. The Return of the Cultural Exception and its Impact on International Agreements

    Directory of Open Access Journals (Sweden)

    Marlen Bartsch

    2014-07-01

    Full Text Available This essay examines the influence of the French concept of the “cultural exception” on European media policy and international agreements. After briefly reviewing the historical background of the cultural exception in France, the essay describes how demands for the cultural exception and those for diversity affect inter-/transnational agreements within the European Union and around the world. Special focus is placed on the current secret EU/US Transatlantic Trade and Investment Partnership Agreement (TTIP negotiations that nearly failed because of France’s insistence that media and culture be exempted. The author argues that the concept of the “cultural exception” has been revived in recent years. However, due to the dual character of media (which is both a cultural and economic good, and the lack of a global media policy, the culture and trade debate will continue.

  3. Managing the financial cost of exception to contracting standards

    DEFF Research Database (Denmark)

    Henschel, Rene Franz

    2008-01-01

    In managing financial cost of exception to contracting standards, the first step is to put up an intelligent contract standards exception monitoring system The next step is to maintain tailor-made, fair and transparent contracting standards The third step is to eliminate unnecessary information...... and repetitiveness in contracting standards The fourth step is to enable your organization and the customers or suppliers to handle the necessary exceptions themselves Finally you should consider the use of independent contracting standards and elimination of your own standards as a tool in managing the cost...

  4. Does staff diversity imply openness to diversity?

    DEFF Research Database (Denmark)

    Lauring, Jakob; Selmer, Jan

    2013-01-01

    Purpose – Post-secondary educational organizations are currently some of the most diverse settings to be found. However, few educational studies have dealt with staff diversity and hardly any has looked outside the USA. The purpose of this paper is to present a study of members of international...... university departments in Denmark. The authors set out to investigate the relationship between different types of staff diversity and openness to diversity in terms of linguistic, visible, value, and informational heterogeneity. Design/methodology/approach – This study uses responses from 489 staff members......, was unrelated or negatively associated with positive diversity attitudes. Originality/value – Few studies deal with the role of staff diversity and no prior studies the authors know of have examined the link between diversity types and openness to diversity....

  5. Potential use of the non-random distribution of N2 and N2O mole masses in the atmosphere as a tool for tracing atmospheric mixing and isotope fractionation processes

    International Nuclear Information System (INIS)

    Well, R.; Langel, R.; Reineking, A.

    2002-01-01

    The variation in the natural abundance of 15 N in atmospheric gas species is often used to determine the mixing of trace gases from different sources. With conventional budget calculations one unknown quantity can be determined if the remaining quantities are known. From 15 N tracer studies in soils with highly enriched 15 N-nitrate a procedure is known to calculate the mixing of atmospheric and soil derived N 2 based on the measurement of the 30/28 and 29/28 ratios in gas samples collected from soil covers. Because of the non-random distribution of the mole masses 30 N 2 , 29 N 2 and 28 N 2 in the mixing gas it is possible to calculate two quantities simultaneously, i.e. the mixing ratio of atmospheric and soil derived N 2 , and the isotopic signature of the soil derived N 2 . Routine standard measurements of laboratory air had suggested a non-random distribution of N 2 -mole masses. The objective of this study was to investigate and explain the existence of non-random distributions of 15 N 15 N, 14 N 15 N and 14 N 14 N in N 2 and N 2 O in environmental samples. The calculation of theoretical isotope data resulting from hypothetical mixing of two sources differing in 15 N natural abundance demonstrated, that the deviation from an ideal random distribution of mole masses is not detectable with the current precision of mass spectrometry. 15 N-analysis of N 2 or N 2 O was conducted with randomised and non-randomised replicate samples of different origin. 15 N abundance as calculated from 29/28 ratios were generally higher in randomised samples. The differences between the treatments ranged between 0.05 and 0.17 δper mille 15 N. It was concluded that the observed randomisation effect is probably caused by 15 N 15 N fractionation during environmental processes. (author)

  6. 32 CFR 644.86 - Exceptions and reservations.

    Science.gov (United States)

    2010-07-01

    ... roads, public highways, public utilities, railroads and pipelines,” and “to the reservations, exceptions... or District Engineer, such as requirement to install the pipeline underground and at a specified...

  7. Vulnerability of historical masonry buildings under exceptional actions

    OpenAIRE

    Florio, Gilda

    2010-01-01

    The topic of this thesis is the vulnerability assessment of historical masonry buildings under exceptional actions. In order to develop the study, the structural performance of masonry aggregates and isolated monumental buildings under extreme loading condition have been investigated.

  8. Vendors: Gifts Are the Exception to the Rule.

    Science.gov (United States)

    Natale, Jo Anna

    1992-01-01

    Informal interviews with several people working in different industries reveal that, without exception, the vendors say companies do not routinely offer school officials gifts and entertainment to sway purchasing decisions, but that it does happen. (MLF)

  9. 15 CFR 732.4 - Steps regarding License Exceptions.

    Science.gov (United States)

    2010-01-01

    ... General Prohibition Six (Embargo), consult part 746 of the EAR for applicable License Exceptions. (b... export or reexport is subject to General Prohibition Six (Embargo) for embargoed destinations, License...

  10. 49 CFR 89.7 - Exceptions to delegated authority.

    Science.gov (United States)

    2010-10-01

    ... not apply to any claim: (a) As to which there is an indication of (1) fraud; (2) the presentation of a... the claim; (b) Based on tax statutes; or (c) Arising from an exception made by the General Accounting...

  11. Framing charitable donations as exceptional expenses increases giving.

    Science.gov (United States)

    Sussman, Abigail B; Sharma, Eesha; Alter, Adam L

    2015-06-01

    Many articles have examined the psychological drivers of charitable giving, but little is known about how people mentally budget for charitable gifts. The present research aims to address this gap by investigating how perceptions of donations as exceptional (uncommon and infrequent) rather than ordinary (common and frequent) expenses might affect budgeting for and giving to charity. We provide the first demonstration that exceptional framing of an identical item can directly influence mental budgeting processes, and yield societal benefits. In 5 lab and field experiments, exceptional framing increased charitable behavior, and diminished the extent to which people considered the effect of the donation on their budgets. The current work extends our understanding of mental accounting and budgeting for charitable gifts, and demonstrates practical techniques that enable fundraisers to enhance the perceived exceptionality of donations. (c) 2015 APA, all rights reserved).

  12. Stark laws and fair market value exceptions: an introduction.

    Science.gov (United States)

    Siebrasse, Paul B

    2007-01-01

    This article will focus on one aspect of complexity in modern healthcare, namely the implications of Stark laws and other fraud and abuse provisions, including anti-kickback statutes and HIPAA. Also, this article explores the prevalence of fair market value as an exception in the Stark laws and discusses the meanings of those exceptions. Finally, the article explores basic approaches to assessing fair market value, including cost, income, and marketing approaches.

  13. Making operations on standard-library containers strongly exception safe

    DEFF Research Database (Denmark)

    Katajainen, Jyrki

    2007-01-01

    -library containers to provide the strong guarantee of exception safety, instead of the default guarantee, without violating the stringent performance requirements specified in the C++ standard. In particular, we show that every strongly exception-safe operation on dynamic arrays and ordered dictionaries is only...... a constant factor slower than the corresponding default-guarantee operation. In terms of the amount of space, the overhead introduced is linear in the number of elements stored....

  14. THE EXCEPTION OF UNCONSTITUTIONALITY RAISED BEFORE AN INTERNATIONAL ARBITRAL TRIBUNAL

    OpenAIRE

    Eugen HURUBÃ; Luminita GABURA

    2014-01-01

    The main aim of the paper work is to determine whether the Constitutional Court of Romania could be notified by international tribunals in relation to cases tried under Romanian law. On 5 March 2013 the Constitutional Court of Romania decided, for the first time, on a case concerning an exception of unconstitutionality raised before an international tribunal of commercial arbitration. The exception of unconstitutionality of a Government Emergency Ordinance was raised in an arbitration case pe...

  15. Diversity: A Philosophical Perspective

    Directory of Open Access Journals (Sweden)

    Sahotra Sarkar

    2010-01-01

    Full Text Available In recent years, diversity, whether it be ecological, biological, cultural, or linguistic diversity, has emerged as a major cultural value. This paper analyzes whether a single concept of diversity can underwrite discussions of diversity in different disciplines. More importantly, it analyzes the normative justification for the endorsement of diversity as a goal in all contexts. It concludes that no more than a relatively trivial concept of diversity as richness is common to all contexts. Moreover, there is no universal justification for the endorsement of diversity. Arguments to justify the protection of diversity must be tailored to individual contexts.

  16. Obama’s Dual Discourse on American Exceptionalism

    Directory of Open Access Journals (Sweden)

    Hrnjaz Miloš

    2015-08-01

    Full Text Available This paper analyses the highly contested concept of American exceptionalism, as described in the speeches of Barak Obama. The authors of the paper use discourse analysis to show that Obama is using the idea of American exceptionalism on two levels: US foreign policy and the US stance towards international law. Our conclusion is that Obama uses an implicit dual discourse in both these fields. Obama favours active US foreign policy, based on soft power instruments and multilateralism. He insists that American exceptionalism does not mean that the US can exempt itself from the norms of international law, however, he does not think the US should always have a very active foreign policy. He makes room for unilateral acting and the use of hard power instruments in foreign policy. He allows for the use of force even if is not in accordance with the norms of international law, when US national interests are threatened.

  17. Exceptional points enhance sensing in an optical microcavity

    Science.gov (United States)

    Chen, Weijian; Kaya Özdemir, Şahin; Zhao, Guangming; Wiersig, Jan; Yang, Lan

    2017-08-01

    Sensors play an important part in many aspects of daily life such as infrared sensors in home security systems, particle sensors for environmental monitoring and motion sensors in mobile phones. High-quality optical microcavities are prime candidates for sensing applications because of their ability to enhance light-matter interactions in a very confined volume. Examples of such devices include mechanical transducers, magnetometers, single-particle absorption spectrometers, and microcavity sensors for sizing single particles and detecting nanometre-scale objects such as single nanoparticles and atomic ions. Traditionally, a very small perturbation near an optical microcavity introduces either a change in the linewidth or a frequency shift or splitting of a resonance that is proportional to the strength of the perturbation. Here we demonstrate an alternative sensing scheme, by which the sensitivity of microcavities can be enhanced when operated at non-Hermitian spectral degeneracies known as exceptional points. In our experiments, we use two nanoscale scatterers to tune a whispering-gallery-mode micro-toroid cavity, in which light propagates along a concave surface by continuous total internal reflection, in a precise and controlled manner to exceptional points. A target nanoscale object that subsequently enters the evanescent field of the cavity perturbs the system from its exceptional point, leading to frequency splitting. Owing to the complex-square-root topology near an exceptional point, this frequency splitting scales as the square root of the perturbation strength and is therefore larger (for sufficiently small perturbations) than the splitting observed in traditional non-exceptional-point sensing schemes. Our demonstration of exceptional-point-enhanced sensitivity paves the way for sensors with unprecedented sensitivity.

  18. Managing Workplace Diversity

    OpenAIRE

    Harold Andrew Patrick; Vincent Raj Kumar

    2012-01-01

    Diversity management is a process intended to create and maintain a positive work environment where the similarities and differences of individuals are valued. The literature on diversity management has mostly emphasized on organization culture; its impact on diversity openness; human resource management practices; institutional environments and organizational contexts to diversity-related pressures, expectations, requ...

  19. Confinement in F4 Exceptional Gauge Group Using Domain Structures

    Science.gov (United States)

    Rafibakhsh, Shahnoosh; Shahlaei, Amir

    2017-03-01

    We calculate the potential between static quarks in the fundamental representation of the F4 exceptional gauge group using domain structures of the thick center vortex model. As non-trivial center elements are absent, the asymptotic string tension is lost while an intermediate linear potential is observed. SU(2) is a subgroup of F4. Investigating the decomposition of the 26 dimensional representation of F4 to the SU(2) representations, might explain what accounts for the intermediate linear potential, in the exceptional groups with no center element.

  20. Low diversity in the mitogenome of sperm whales revealed by next-generation sequencing

    Science.gov (United States)

    Alana Alexander; Debbie Steel; Beth Slikas; Kendra Hoekzema; Colm Carraher; Matthew Parks; Richard Cronn; C. Scott Baker

    2012-01-01

    Large population sizes and global distributions generally associate with high mitochondrial DNA control region (CR) diversity. The sperm whale (Physeter macrocephalus) is an exception, showing low CR diversity relative to other cetaceans; however, diversity levels throughout the remainder of the sperm whale mitogenome are unknown. We sequenced 20...

  1. Speaking from Otherness: A New Perspective on U.S. Diversity and Suggestions to Educational Equality

    Science.gov (United States)

    Li, Nan

    2005-01-01

    For a Chinese educator residing in the United States, one distinctive characteristic of American culture is diversity. The United States is a nation comprised of diversity in race, ethnicity, religion, socioeconomic (SES) status, exceptionality, gender, age, and language. Diversity, on one hand, distinguishes the United States and contributes to…

  2. 7 CFR 305.17 - Authorized treatments; exceptions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Authorized treatments; exceptions. 305.17 Section 305.17 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH..., Libya, Malta, Macedonia, Morocco, Sardinia, Serbia and Montenegro, Slovenia, Spain, Syria, Tunisia, and...

  3. 27 CFR 28.295 - Exception for export of beer.

    Science.gov (United States)

    2010-04-01

    ... beer. 28.295 Section 28.295 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Alternate Procedures § 28.295 Exception for export of beer. The provisions of this subpart do not apply in the case of beer when the exporter or claimant obtains proof of exportation other than certification...

  4. The Acceptance of Exceptionality: A Three Dimensional Model.

    Science.gov (United States)

    Martin, Larry L.; Nivens, Maryruth K.

    A model extrapolates from E. Kubler-Ross' conception of the stages of grief to apply to parent and family reactions when an exceptionality is identified. A chart lists possible parent feelings and reactions, possible school reactions to the parent in grief, and the child's reactions during each of five stages: denial, rage and anger, bargaining,…

  5. 15 CFR 700.80 - Adjustments or exceptions.

    Science.gov (United States)

    2010-01-01

    ...) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS... exceptions. (a) A person may submit a request to the Office of Strategic Industries and Economic Security, U... interim relief is granted in writing by the Office of Strategic Industries and Economic Security. (d) A...

  6. 26 CFR 31.3221-4 - Exception from supplemental tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 15 2010-04-01 2010-04-01 false Exception from supplemental tax. 31.3221-4...) EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE EMPLOYMENT TAXES AND COLLECTION OF INCOME TAX AT SOURCE Railroad Retirement Tax Act (Chapter 22, Internal Revenue Code of 1954) Tax on Employers § 31.3221...

  7. 24 CFR 203.41 - Free assumability; exceptions.

    Science.gov (United States)

    2010-04-01

    ... otherwise provided in the HOME Investment Partnerships (HOME) and the Homeownership and Opportunity for... limitations applicable in the jurisdiction. (3) Except as otherwise required by the HOME and HOPE programs... that the holder of the right of entry for condition broken also executes the mortgage, and that the...

  8. 26 CFR 301.7701(b)-2 - Closer connection exception.

    Science.gov (United States)

    2010-04-01

    ...) Duration and nature of tax home. The tax home maintained by the alien individual must be in existence for... exception. (a) In general. An alien individual who meets the substantial presence test may nevertheless be considered a nonresident alien for the current year if the following conditions are satisfied— (1) The...

  9. Brazil's Exception to the World-Class University Movement

    Science.gov (United States)

    Alperin, Juan Pablo

    2013-01-01

    The continued importance of university rankings has only served to fuel the growth of the "world-class" university movement. There is a growing impression that, in a globalised and interconnected world, no country can do without a world-class university. No country, that is, except Brazil. While Brazil has the resources necessary to…

  10. Feeling Abnormal: Simulation of Deviancy in Abnormal and Exceptionality Courses.

    Science.gov (United States)

    Fernald, Charles D.

    1980-01-01

    Describes activity in which student in abnormal psychology and psychology of exceptional children classes personally experience being judged abnormal. The experience allows the students to remember relevant research, become sensitized to the feelings of individuals classified as deviant, and use caution in classifying individuals as abnormal.…

  11. Non-Trade Concerns in Interpreting General Exception Clauses of ...

    African Journals Online (AJOL)

    eliasn

    Primarily, the objective of the measure must fall within the scope of any of the ... Balancing the Toothless Tiger and the Undermining Mole”, Journal of ..... listed in the exception clauses, there is a significant risk for abuse if they are left.

  12. 76 FR 70975 - Petition Requesting Exception From Lead Content Limits

    Science.gov (United States)

    2011-11-16

    ... information provided, to http://www.regulations.gov . Do not submit confidential business information, trade... of divisions: Scale Models and Dyersville Die Cast (``petitioner''), submitted a petition requesting an exception from the lead content limit of 100 ppm under section 101(b) of the CPSIA for its die...

  13. Control of exceptional points in photonic crystal slabs

    DEFF Research Database (Denmark)

    Kaminski, Piotr Marek; Taghizadeh, Alireza; Breinbjerg, Olav

    2017-01-01

    Various ways of controlling the extent of the ring of exceptional points in photonic crystal slabs are investigated. The extent of the ring in photonic crystal slabs is found to vary with the thickness of the slab. This enables recovery of Dirac cones in open, non-Hermitian systems, such as a pho...

  14. Computer Use and Behavior Problems in Twice-Exceptional Students

    Science.gov (United States)

    Alloway, Tracy Packiam; Elsworth, Miquela; Miley, Neal; Seckinger, Sean

    2016-01-01

    This pilot study investigated how engagement with computer games and TV exposure may affect behaviors of gifted students. We also compared behavioral and cognitive profiles of twice-exceptional students and children with Attention Deficit/Hyperactivity Disorder (ADHD). Gifted students were divided into those with behavioral problems and those…

  15. 19 CFR 134.33 - J-List exceptions.

    Science.gov (United States)

    2010-04-01

    ... planed, tongued and grooved T.D.s 49750; 50366(6). Flowers, artificial, except bunches. Flowers, cut... dimensions, shape or form. Monuments. Nails, spikes, and staples. Natural products, such as vegetables...) T.D. 49750. Skins, fur, dressed or dyed. Skins, raw fur. Sponges. Springs, watch. Stamps, postage...

  16. An exceptional collision tumor: gastric calcified stromal tumor and ...

    African Journals Online (AJOL)

    The authors report an exceptional case of collision tumor comprised of a gastric calcified stromal tumor and a pancreatic adenocarcinoma. The pancreatic tumor was detected fortuitously on the histological exam of resection specimen. Key words: Collision tumor, stromal tumor, adenocarcinoma ...

  17. Generalized Fano lineshapes reveal exceptional points in photonic molecules

    NARCIS (Netherlands)

    Caselli, N.; Intonti, F.; La China, Federico; Biccari, F.; Riboli, F.; Gerardino, A.; Li, L.; Linfield, E.H.; Pagliano, F.; Fiore, A.; Gurioli, M.

    2018-01-01

    The optical behavior of coupled systems, in which the breaking of parity and time-reversal symmetry occurs, is drawing increasing attention to address the physics of the exceptional point singularity, i.e., when the real and imaginary parts of the normal-mode eigenfrequencies coincide. At this

  18. Exceptional Lie groups, E-infinity theory and Higgs Boson

    International Nuclear Information System (INIS)

    El-Okaby, Ayman A.

    2008-01-01

    In this paper we study the correlation between El-Naschie's exceptional Lie groups hierarchies and his transfinite E-infinity space-time theory. Subsequently this correlation is used to calculate the number of elementary particles in the standard model, mass of the Higgs Bosons and some coupling constants

  19. An Exception Handling Service for Software Agent Ensembles

    National Research Council Canada - National Science Library

    Klein, Mark

    2004-01-01

    ... (I) the creation of better contingent contracts between agents (both human and software- based) as well as (2) exception-handling agents that monitor MAS for problem symptoms, diagnose the underlying problems, and intervene as appropriate to avoid or resolve these problems.

  20. Leading Change: How Boards and Presidents Build Exceptional Academic Institutions

    Science.gov (United States)

    MacTaggart, Terrence

    2011-01-01

    In a time of transformation in higher education, "Leading Change: How Boards and Presidents Build Exceptional Institutions" fills a significant void in leadership literature and focuses on the changing level of board engagement. This book examines 18 institutions, across the spectrum of higher education, at which the board played a…

  1. 26 CFR 1.1245-4 - Exceptions and limitations.

    Science.gov (United States)

    2010-04-01

    ... of the property in the hands of the son is $110,000. (b) Exception for transfers at death—(1) General... property which, upon Smith's death, is inherited by his son. Since the property is described in section..., and after B's death to distribute the property to C. If the basis of the property to the fiduciary and...

  2. 46 CFR 520.13 - Exemptions and exceptions.

    Science.gov (United States)

    2010-10-01

    ... AUTOMATED TARIFFS § 520.13 Exemptions and exceptions. (a) General. Exemptions from the requirements of this... for the purpose of sale. (ii) British Columbia and Puget Sound Ports; rail cars—(A) Through rates. Transportation by water of cargo moving in rail cars between British Columbia, Canada and United States ports on...

  3. Multiply Degenerate Exceptional Points and Quantum Phase Transitions

    Czech Academy of Sciences Publication Activity Database

    Borisov, D.; Růžička, František; Znojil, Miloslav

    2015-01-01

    Roč. 54, č. 12 (2015), s. 4293-4305 ISSN 0020-7748 Institutional support: RVO:61389005 Keywords : quantum mechanics * Cryptohermitian observbles * spectra and pseudospectra * real exceptional points * phase transitions Subject RIV: BE - Theoretical Physics Impact factor: 1.041, year: 2015

  4. 26 CFR 1.461-5 - Recurring item exception.

    Science.gov (United States)

    2010-04-01

    ... general. Except as otherwise provided in paragraph (c) of this section, a taxpayer using an accrual method... method of accounting for one or more types of recurring items incurred by the taxpayer. In the case of... basis in the future. (4) Materiality requirement. For purposes of this paragraph (b): (i) In determining...

  5. 38 CFR 4.86 - Exceptional patterns of hearing impairment.

    Science.gov (United States)

    2010-07-01

    ... hearing impairment. 4.86 Section 4.86 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE FOR RATING DISABILITIES Disability Ratings Impairment of Auditory Acuity § 4.86 Exceptional patterns of hearing impairment. (a) When the puretone threshold at each of the four specified...

  6. 31 CFR 206.5 - Collection and deposit procedure exceptions.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Collection and deposit procedure exceptions. 206.5 Section 206.5 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL...

  7. Technology and Media for Exceptional Learners: Looking Ahead

    Science.gov (United States)

    Lance, Wayne D.

    1977-01-01

    The author points out the need for greater application of technology in educational programs for exceptional children and suggests ways in which new developments (such as computer applications, video, sensory compensation devices, and communication satellite technology) can be used to implement some of the requirements of Public Law 94-142. (IM)

  8. Morphological diversity in tenrecs (Afrosoricida, Tenrecidae: comparing tenrec skull diversity to their closest relatives

    Directory of Open Access Journals (Sweden)

    Sive Finlay

    2015-04-01

    Full Text Available It is important to quantify patterns of morphological diversity to enhance our understanding of variation in ecological and evolutionary traits. Here, we present a quantitative analysis of morphological diversity in a family of small mammals, the tenrecs (Afrosoricida, Tenrecidae. Tenrecs are often cited as an example of an exceptionally morphologically diverse group. However, this assumption has not been tested quantitatively. We use geometric morphometric analyses of skull shape to test whether tenrecs are more morphologically diverse than their closest relatives, the golden moles (Afrosoricida, Chrysochloridae. Tenrecs occupy a wider range of ecological niches than golden moles so we predict that they will be more morphologically diverse. Contrary to our expectations, we find that tenrec skulls are only more morphologically diverse than golden moles when measured in lateral view. Furthermore, similarities among the species-rich Microgale tenrec genus appear to mask higher morphological diversity in the rest of the family. These results reveal new insights into the morphological diversity of tenrecs and highlight the importance of using quantitative methods to test qualitative assumptions about patterns of morphological diversity.

  9. Capturing the Diversity in Lexical Diversity

    Science.gov (United States)

    Jarvis, Scott

    2013-01-01

    The range, variety, or diversity of words found in learners' language use is believed to reflect the complexity of their vocabulary knowledge as well as the level of their language proficiency. Many indices of lexical diversity have been proposed, most of which involve statistical relationships between types and tokens, and which ultimately…

  10. CERN Diversity Newsletter - March 2016

    CERN Document Server

    Kaltenhauser, Kristin; CERN. Geneva. HR Department

    2016-01-01

    Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter

  11. CERN Diversity Newsletter - April 2017

    CERN Document Server

    AUTHOR|(CDS)2069427; Koutava, Ioanna; CERN. Geneva. HR Department

    2017-01-01

    The CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter

  12. CERN Diversity Newsletter - November 2015

    CERN Document Server

    Kaltenhauser, Kristin; CERN. Geneva. HR Department

    2015-01-01

    Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter

  13. CERN Diversity Newsletter - September 2016

    CERN Document Server

    Guinot, Genevieve

    2016-01-01

    Quarterly CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter

  14. What Is Nigeria? Unsettling the Myth of Exceptionalism

    Directory of Open Access Journals (Sweden)

    Aghogho Akpome

    2015-01-01

    Full Text Available This article explores perceptions and representations of Nigeria and Nigerians in the popular global imaginary. It analyses selected popular media narratives in order to foreground contradictions and paradoxes in the ways in which the country and people of Nigeria are discursively constructed. By doing so, it interrogates stereotypes of corruption and criminality as well as myths of exceptionalism about Nigeria and Nigerians originating from both within and outside the country. The analysis reveals that the generalised portrayal of Nigeria and Nigerians as exceptional social subjects is characterised by contradictions and inaccuracies in dominant representational practices and cannot be justified by the verifiable empirical information available on the country and its people.

  15. The Dilemma of Democracy: Collusion and the State of Exception

    Directory of Open Access Journals (Sweden)

    Mark McGovern

    2011-12-01

    Full Text Available In what sense might the authoritarian practices and suspension of legal norms as means to combat the supposed threat of “terrorism,” within and by contemporary western democratic states, be understood as a problem of and not for democracy? That question lies at the heart of this article. It will be explored through the theoretical frame offered in the work of Giorgio Agamben on the state of exception and the example of British state collusion in non-state violence in the North of Ireland. The North of Ireland provides a particularly illuminating case study to explore how the state of exception—the suspension of law and of legal norms and the exercise of arbitrary decision—has increasingly become a paradigm of contemporary governance. In so doing it brings into question not only the traditional conceptualization of the “democratic dilemma” of liberal democratic states “confronting terrorism” but also challenge dominant paradigms of transitional justice that generally fail to problematize the liberal democratic order. After outlining Agamben’s understanding of the state of exception the article will chart the development of “exceptional measures” and the creation of a permanent state of emergency in the North, before critically exploring the role of collusion as an aspect of counter-insurgency during the recent conflict. The paper will argue that the normalization of exceptional measures, combined with the need to delimit the explicitness of constitutional provision for the same, provided a context for the emergence of collusion as a paradigm case for the increasing replication of colonial practices into the core activity of the contemporary democratic state.

  16. Baroque Poetics and the Logic of Hispanic Exceptionalism

    OpenAIRE

    Young, Allen

    2012-01-01

    Baroque Poetics and the Logic of Hispanic Exceptionalismby Allen YoungIn this dissertation I study the how the baroque is used to understand aesthetic modernity in twentieth-century Spain and Latin America. My argument is that the baroque, in contemporary Hispanic and Latin American studies, functions as a myth of cultural exceptionalism, letting critics recast avant-garde and postmodern innovation as fidelity to a timeless essence or identity. That is, by viewing much contemporary Spanish-la...

  17. Environmental Licensing: an Instrument of Command and Control by Exception?

    OpenAIRE

    Sleman Chams, Juliette; Gestión Ambiental de la Corporación Autónoma Regional del Atlántico-CRA, autoridad ambiental del Departamento del Atlántico,; Velásquez Muñoz, Carlos Javier; Universidad del Norte (Barranquilla)

    2016-01-01

    This article analyzes the situation of the most important instrument of command and control existing in the Colombian environmental legislation: the environmental license. Since its first formal regulation, on behalf of Decree 1753 of August 3, 1994, has received several modifications which, apparently, have made, in spite of its importance, in an instrument of command and control by exception. The article revises on the scope of each of the modifications and the justifications put forward by...

  18. Families of superintegrable Hamiltonians constructed from exceptional polynomials

    International Nuclear Information System (INIS)

    Post, Sarah; Tsujimoto, Satoshi; Vinet, Luc

    2012-01-01

    We introduce a family of exactly-solvable two-dimensional Hamiltonians whose wave functions are given in terms of Laguerre and exceptional Jacobi polynomials. The Hamiltonians contain purely quantum terms which vanish in the classical limit leaving only a previously known family of superintegrable systems. Additional, higher-order integrals of motion are constructed from ladder operators for the considered orthogonal polynomials proving the quantum system to be superintegrable. (paper)

  19. Democracy, justice and state of exception: past present

    Directory of Open Access Journals (Sweden)

    Tásso Araújo Brito

    2017-06-01

    Full Text Available Violence against portions of society, disbelief in democratic institutions and agents of the state who inflict torture against those who are in their custody are elements that corrode the Brazilian democracy. Between the past of the military-civilian dictatorship and the current moment we realize how practices that have been considered exceptions have become rules that affect the life of many Brazilian citizens. The present paper investigates these political experiences to ask which democracy have we been living in.

  20. An exceptional case of bilateral gestational gigantomastia with ...

    African Journals Online (AJOL)

    Histological analysis revealed a fibroadenoma. Her prolactin level after caesarean delivery was found particularly high. A significant decrease in breast size was achieved with bromocriptine treatment in conjunction with a bilateral lumpectomy. This case report highlights the diversity of gigantomastia and emphasizes the ...

  1. Managing Workplace Diversity

    Directory of Open Access Journals (Sweden)

    Harold Andrew Patrick

    2012-04-01

    Full Text Available Diversity management is a process intended to create and maintain a positive work environment where the similarities and differences of individuals are valued. The literature on diversity management has mostly emphasized on organization culture; its impact on diversity openness; human resource management practices; institutional environments and organizational contexts to diversity-related pressures, expectations, requirements, and incentives; perceived practices and organizational outcomes related to managing employee diversity; and several other issues. The current study examines the potential barriers to workplace diversity and suggests strategies to enhance workplace diversity and inclusiveness. It is based on a survey of 300 IT employees. The study concludes that successfully managing diversity can lead to more committed, better satisfied, better performing employees and potentially better financial performance for an organization.

  2. Teaching Culturally Diverse Students.

    Science.gov (United States)

    Correa, Vivian; Tulbert, Beth

    1991-01-01

    Characteristics of culturally diverse students are discussed in terms of language, culture, and socioeconomic factors. Meeting the educational needs of culturally diverse students can involve interactive teaming of professionals; parent involvement; and providing appropriate services, assessment, curriculum, and instruction. (JDD)

  3. Half-maximal supersymmetry from exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Malek, Emanuel [Arnold Sommerfeld Center for Theoretical Physics, Department fuer Physik, Ludwig-Maximilians-Universitaet Muenchen (Germany)

    2017-10-15

    We study D ≥ 4-dimensional half-maximal flux backgrounds using exceptional field theory. We define the relevant generalised structures and also find the integrability conditions which give warped half-maximal Minkowski{sub D} and AdS{sub D} vacua. We then show how to obtain consistent truncations of type II / 11-dimensional SUGRA which break half the supersymmetry. Such truncations can be defined on backgrounds admitting exceptional generalised SO(d - 1 - N) structures, where d = 11 - D, and N is the number of vector multiplets obtained in the lower-dimensional theory. Our procedure yields the most general embedding tensors satisfying the linear constraint of half-maximal gauged SUGRA. We use this to prove that all D ≥ 4 half-maximal warped AdS{sub D} and Minkowski{sub D} vacua of type II / 11-dimensional SUGRA admit a consistent truncation keeping only the gravitational supermultiplet. We also show to obtain heterotic double field theory from exceptional field theory and comment on the M-theory / heterotic duality. In five dimensions, we find a new SO(5, N) double field theory with a (6 + N)-dimensional extended space. Its section condition has one solution corresponding to 10-dimensional N = 1 supergravity and another yielding six-dimensional N = (2, 0) SUGRA. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. Intersectionality, Diversity and Gender

    DEFF Research Database (Denmark)

    Agustin, Lise Rolandsen; Siim, Birte

    2016-01-01

    In the discourses of Danish politicians on ethno-national diversity and integration, the notion of diversity is gendered, especially the articulation of the ‘working woman’ and her labor market participation. Equality, diversity and gender are, thus, intertwined in political, discursive construct...

  5. Leadership and Diversity

    Science.gov (United States)

    Coleman, Marianne

    2012-01-01

    As part of the special edition recognizing the 40th anniversary of "Educational Management Administration & Leadership" this article reviews the coverage of leadership and diversity issues in the journal. The majority of articles concerning diversity have focused on gender, with attention turning to the wider concept of diversity since the year…

  6. Diversity cognition and climates

    NARCIS (Netherlands)

    van Knippenberg, D.; Homan, A.C.; van Ginkel, W.; Roberson, Q.M.

    2013-01-01

    Demographic diversity at work can yield performance benefits but also invite psychological disengagement and be a source of interpersonal tension. In managing this double-edged sword of demographic diversity, the role of diversity cognition (beliefs, attitudes) and climates seems particularly

  7. Take action: influence diversity.

    Science.gov (United States)

    Gomez, Norma J

    2013-01-01

    Increased diversity brings strength to nursing and ANNA. Being a more diverse association will require all of us working together. There is an old proverb that says: "one hand cannot cover the sky; it takes many hands." ANNA needs every one of its members to be a part of the diversity initiative.

  8. Flexible Ferroelectric Sensors with Ultrahigh Pressure Sensitivity and Linear Response over Exceptionally Broad Pressure Range.

    Science.gov (United States)

    Lee, Youngoh; Park, Jonghwa; Cho, Soowon; Shin, Young-Eun; Lee, Hochan; Kim, Jinyoung; Myoung, Jinyoung; Cho, Seungse; Kang, Saewon; Baig, Chunggi; Ko, Hyunhyub

    2018-04-24

    Flexible pressure sensors with a high sensitivity over a broad linear range can simplify wearable sensing systems without additional signal processing for the linear output, enabling device miniaturization and low power consumption. Here, we demonstrate a flexible ferroelectric sensor with ultrahigh pressure sensitivity and linear response over an exceptionally broad pressure range based on the material and structural design of ferroelectric composites with a multilayer interlocked microdome geometry. Due to the stress concentration between interlocked microdome arrays and increased contact area in the multilayer design, the flexible ferroelectric sensors could perceive static/dynamic pressure with high sensitivity (47.7 kPa -1 , 1.3 Pa minimum detection). In addition, efficient stress distribution between stacked multilayers enables linear sensing over exceptionally broad pressure range (0.0013-353 kPa) with fast response time (20 ms) and high reliability over 5000 repetitive cycles even at an extremely high pressure of 272 kPa. Our sensor can be used to monitor diverse stimuli from a low to a high pressure range including weak gas flow, acoustic sound, wrist pulse pressure, respiration, and foot pressure with a single device.

  9. Language and Identities: The Exceptional Normality of Italy

    Directory of Open Access Journals (Sweden)

    John J. Kinder

    2008-10-01

    Full Text Available Language issues loom large in current debates on Italian identity/identities, indigenous minorities in Italy and, of course, immigration. While the context of language debates in early 21st century Italy presents new realities and challenges, the fundamental issues are the same as those originally defined by the first European language planner, Dante, and reworked by successive theorists. The debates turn on exclusions and inclusions, on levels of multiple identities, on understandings of otherness. It is no accident that language is at once as a provocation for debates on identity and a metaphor of those debates, for the tensions that run through the debates lie at the heart of language itself. All cultures have a narrative that explains diversity among languages and cultures, either as the result of a mistake or as divine punishment. The Biblical accounts of Creation, Babel and Pentecost provide the framework for European understandings of language diversity. These accounts capture the paradoxical nature of human language, which characterizes us a species and is a tool for building unity between persons and groups, but is, by its nature, always and inevitably an expression of diversity, in time and space. These contradictions are being played out in current language debates as emigration, return migration, internal migration and immigration elicit new constructions of ‘Italianness’, the literary canon and the social weight of the different varieties of language present on Italian soil and in Italian communities abroad.

  10. Linking Diversity and Differentiation

    Directory of Open Access Journals (Sweden)

    Hans-Rolf Gregorius

    2010-03-01

    Full Text Available Generally speaking, the term differentiation refers to differences between collections for the distribution of specified traits of their members, while diversity deals with (effective numbers of trait states (types. Counting numbers of types implies discrete traits such as alleles and genotypes in population genetics or species and taxa in ecology. Comparisons between the concepts of differentiation and diversity therefore primarily refer to discrete traits. Diversity is related to differentiation through the idea that the total diversity of a subdivided collection should be composed of the diversity within the subcollections and a complement called “diversity between subcollections”. The idea goes back to the perception that the mixing of differentiated collections increases diversity. Several existing concepts of “diversity between subcollections” are based on this idea. Among them, β-diversity and fixation (inadvertently called differentiation are the most prominent in ecology and in population genetics, respectively. The pertaining measures are shown to quantify the effect of differentiation in terms of diversity components, though from a dual perspective: the classical perspective of differentiation between collections for their type compositions, and the reverse perspective of differentiation between types for their collection affiliations. A series of measures of diversity-oriented differentiation is presented that consider this dual perspective at two levels of diversity partitioning: the overall type or subcollection diversity and the joint type-subcollection diversity. It turns out that, in contrast with common notions, the measures of fixation (such as FST or GST refer to the perspective of type rather than subcollection differentiation. This unexpected observation strongly suggests that the popular interpretations of fixation measures must be reconsidered.

  11. Scandinavian exceptionalism in anti-doping within sport

    DEFF Research Database (Denmark)

    Tangen, Jan Ove; Møller, Verner

    2017-01-01

    Why are Scandinavian countries so committed to the cause of antidoping? In this paper, we propose that the Scandinavian mentality, formed by paternalistic welfare models, is a useful framework for understanding anti-doping. We focus on anti-doping policy and work in Norway and Denmark. We start w......: the Norwegian self-image and its impact on politics, and Danish amateurism and corrupt idealism. We conclude that Nordic antidoping is pursued with rigour and determination, and suggest this is rooted in the Nordic countries’ exceptional social-welfare ideology and strong paternalism....

  12. Alaska exceptionality hypothesis: Is Alaska wilderness really different?

    Science.gov (United States)

    Gregory Brown

    2002-01-01

    The common idiom of Alaska as “The Last Frontier” suggests that the relative remoteness and unsettled character of Alaska create a unique Alaskan identity, one that is both a “frontier” and the “last” of its kind. The frontier idiom portrays the place and people of Alaska as exceptional or different from the places and people who reside in the Lower Forty- Eight States...

  13. Cigar Lake, an original method for an exceptional deposit

    International Nuclear Information System (INIS)

    Caleix, C.

    1997-01-01

    In 1976, the discovery of the high grade Deposit at Cluff Lake in the north of the province of Saskatchewan (Canada) opened new prospects in uranium deposits, which in turn quickly led to the discovery of exceptional deposits both in terms of grade (up 10 % in metal uranium) and tonnage (150, 000 tons of metal per deposit and more). Among these deposits are Key Lake, Cigar Lake, Midwest, MacClean, and more recently, Mac Arthur. These discoveries as well as future ones make the north of Saskatchewan the world's greatest and most interesting uranium-producing province. (authors)

  14. Finding Exception For Association Rules Via SQL Queries

    Directory of Open Access Journals (Sweden)

    Luminita DUMITRIU

    2000-12-01

    Full Text Available Finding association rules is mainly based on generating larger and larger frequent set candidates, starting from frequent attributes in the database. The frequent sets can be organised as a part of a lattice of concepts according to the Formal Concept Analysis approach. Since the lattice construction is database contents-dependent, the pseudo-intents (see Formal Concept Analysis are avoided. Association rules between concept intents (closed sets A=>B are partial implication rules, meaning that there is some data supporting A and (not B; fully explaining the data requires finding exceptions for the association rules. The approach applies to Oracle databases, via SQL queries.

  15. Break-glass handling exceptional situations in access control

    CERN Document Server

    Petritsch, Helmut

    2014-01-01

    Helmut Petritsch describes the first holistic approach to Break-Glass which covers the whole life-cycle: from access control modeling (pre-access), to logging the security-relevant system state during Break-Glass accesses (at-access), and the automated analysis of Break-Glass accesses (post-access). Break-Glass allows users to override security restrictions in exceptional situations. While several Break-Glass models specific to given access control models have already been discussed in research (e.g., extending RBAC with Break-Glass), the author introduces a generic Break-Glass model. The pres

  16. Construction of codimension 1 immersions of spacetime: the exceptional case

    International Nuclear Information System (INIS)

    Edelen, Dominic G B

    2005-01-01

    The Frobenius theorem was used in Edelen (2003 Class. Quantum Grav. 20 3661) to obtain a general body of results for the immersion of spacetime in flat spaces of higher dimension. This addendum completes those results for the exceptional case of immersions of codimension 1 where the Frobenius theorem need not be applied. Local actions of the Poincare groups SO(2, 3)--T(5) or SO(1, 4) -- T(5) are used to obtain immersions of spacetime of codimension 1 that involve six arbitrary functions of the four immersion parameters and an arbitrary constant. Explicit calculations are given for several cases. (addendum)

  17. Bringing Anomie Back In: Exceptional Events and Excess Suicide

    Directory of Open Access Journals (Sweden)

    Mark Anthony Hoffman

    2015-04-01

    Full Text Available In this article we show that imitation is not the mechanism behind the observed increase in suicides subsequent to highly publicized celebrity suicides. Instead, we show that most celebrity suicides are exceptional events and because of that have similar effects on the daily suicide rate as other exciting events. This finding suggests that Durkheim was right in rejecting the Tardean hypothesis that imitation is an operative mechanism and provides substantial support for the competing hypothesis that disruptive and/or exciting events (whether favorable or unfavorable induce anomie and with it suicide.

  18. Exceptional Ground Accelerations and Velocities Caused by Earthquakes

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, John

    2008-01-17

    This project aims to understand the characteristics of the free-field strong-motion records that have yielded the 100 largest peak accelerations and the 100 largest peak velocities recorded to date. The peak is defined as the maximum magnitude of the acceleration or velocity vector during the strong shaking. This compilation includes 35 records with peak acceleration greater than gravity, and 41 records with peak velocities greater than 100 cm/s. The results represent an estimated 150,000 instrument-years of strong-motion recordings. The mean horizontal acceleration or velocity, as used for the NGA ground motion models, is typically 0.76 times the magnitude of this vector peak. Accelerations in the top 100 come from earthquakes as small as magnitude 5, while velocities in the top 100 all come from earthquakes with magnitude 6 or larger. Records are dominated by crustal earthquakes with thrust, oblique-thrust, or strike-slip mechanisms. Normal faulting mechanisms in crustal earthquakes constitute under 5% of the records in the databases searched, and an even smaller percentage of the exceptional records. All NEHRP site categories have contributed exceptional records, in proportions similar to the extent that they are represented in the larger database.

  19. Architecting Fault Tolerance with Exception Handling: Verification and Validation

    Institute of Scientific and Technical Information of China (English)

    Patrick H. S. Brito; Rogério de Lemos; Cecília M. F. Rubira; Eliane Martins

    2009-01-01

    When building dependable systems by integrating untrusted software components that were not originally designed to interact with each other, it is likely the occurrence of architectural mismatches related to assumptions in their failure behaviour. These mismatches, if not prevented during system design, have to be tolerated during runtime. This paper presents an architectural abstraction based on exception handling for structuring fault-tolerant software systems.This abstraction comprises several components and connectors that promote an existing untrusted software element into an idealised fault-tolerant architectural element. Moreover, it is considered in the context of a rigorous software development approach based on formal methods for representing the structure and behaviour of the software architecture. The proposed approach relies on a formal specification and verification for analysing exception propagation, and verifying important dependability properties, such as deadlock freedom, and scenarios of architectural reconfiguration. The formal models are automatically generated using model transformation from UML diagrams: component diagram representing the system structure, and sequence diagrams representing the system behaviour. Finally, the formal models are also used for generating unit and integration test cases that are used for assessing the correctness of the source code. The feasibility of the proposed architectural approach was evaluated on an embedded critical case study.

  20. 2000 GUIDELINES FOR ADVANCEMENT AND EXCEPTIONAL PERFORMANCE AWARDS

    CERN Document Server

    2000-01-01

    1. GeneralAs indicated in last year's guidelines, studies on CERN's career structures are continuing in the context of the work of the Tripartite Forum on Employment Conditions (TREF) and should be completed during this year's 5-Yearly Remuneration Review for the application of any changes in 2001. In the meantime, the 2000 annual advancement exercise will be conducted on similar basic lines to those of previous years, i.e. within the procedures of the Administrative Circular N° 26 (Rev. 2), thus promoting the aspect of individual merit in advancement.The present guidelines continue to aim at the best possible degree of flexibility of application for each division within the present Staff Rules and Regulations in order to take full account of both the different levels of individual performance and also the different staff profiles.All advancement must be justified on the grounds of correctly judged merit: exceptional advancement (i.e. second step or entering the exceptional advancement grade) for par...

  1. Exceptional points and quantum correlations in precise measurements

    International Nuclear Information System (INIS)

    Thilagam, A

    2012-01-01

    We examine the physical manifestations of exceptional points and passage times in a two-level system which is subjected to quantum measurements and which admits a non-Hermitian description. Using an effective Hamiltonian acting in the two-dimensional space spanned by the evolving initial and final states, the effects of highly precise quantum measurements in which the monitoring device interferes significantly with the evolution dynamics of the monitored two-level system is analyzed. The dynamics of a multipartite system consisting of the two-level system, a source of external potential and the measurement device is examined using correlation measures such as entanglement and non-classical quantum correlations. Results show that the quantum correlations between the monitored (monitoring) systems is considerably decreased (increased) as the measurement precision nears the exceptional point, at which the passage time is half of the measurement duration. The results indicate that the underlying mechanism by which the non-classical correlations of quantum systems are transferred from one subsystem to another may be better revealed via use of geometric approaches. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Quantum physics with non-Hermitian operators’. (paper)

  2. Confrontation Between Judicial Activism and State of Exception

    Directory of Open Access Journals (Sweden)

    Alexandre Pedro Moura D’Almeida

    2017-01-01

    Full Text Available The judiciary has excelled in the international and national scene, reaching role of great importance, thus creating opposition to the legislative and executive powers. The center of gravity of the sovereign power of the state moves toward the judiciary, that happens to have a more active role and controlling of the others powers, but also appears as a great defender of social and fundamental rights causes, seeking to make an effective constitution. Its great public notoriety has attracted great distrust of various sectors of society, especially by the two powers that have an increasing interference. Arises, therefore, a speech that the judiciary would be reversing into a big and uncontrollable power, increasing the suspicion that now it would be living in a real dictatorship of the judiciary through judicial activism. There is a growing concern with the expansion of activism and the role of the judiciary. The purpose of this work is to conceptualize and approach the judicial activism and the state of exception to search and reveal if there is any similarity, to then draw up a possible answer to the concern of forming a dictatorship of the judiciary. The state of exception is one of the rule of law paradoxes, while activism is a political manifestation of the judiciary. The similarity between the institutes appears as appalling in a dynamic expansion of political power of a state institution exercising judicial function, putting in check who would be the sovereign in a rule of law and democratic state.

  3. Exceptionally high levels of recombination across the honey bee genome.

    Science.gov (United States)

    Beye, Martin; Gattermeier, Irene; Hasselmann, Martin; Gempe, Tanja; Schioett, Morten; Baines, John F; Schlipalius, David; Mougel, Florence; Emore, Christine; Rueppell, Olav; Sirviö, Anu; Guzmán-Novoa, Ernesto; Hunt, Greg; Solignac, Michel; Page, Robert E

    2006-11-01

    The first draft of the honey bee genome sequence and improved genetic maps are utilized to analyze a genome displaying 10 times higher levels of recombination (19 cM/Mb) than previously analyzed genomes of higher eukaryotes. The exceptionally high recombination rate is distributed genome-wide, but varies by two orders of magnitude. Analysis of chromosome, sequence, and gene parameters with respect to recombination showed that local recombination rate is associated with distance to the telomere, GC content, and the number of simple repeats as described for low-recombining genomes. Recombination rate does not decrease with chromosome size. On average 5.7 recombination events per chromosome pair per meiosis are found in the honey bee genome. This contrasts with a wide range of taxa that have a uniform recombination frequency of about 1.6 per chromosome pair. The excess of recombination activity does not support a mechanistic role of recombination in stabilizing pairs of homologous chromosome during chromosome pairing. Recombination rate is associated with gene size, suggesting that introns are larger in regions of low recombination and may improve the efficacy of selection in these regions. Very few transposons and no retrotransposons are present in the high-recombining genome. We propose evolutionary explanations for the exceptionally high genome-wide recombination rate.

  4. Consistent Kaluza-Klein truncations via exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Hohm, Olaf [Center for Theoretical Physics, Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Samtleben, Henning [Université de Lyon, Laboratoire de Physique, UMR 5672, CNRS,École Normale Supérieure de Lyon, 46, allée d’Italie, F-69364 Lyon cedex 07 (France)

    2015-01-26

    We present the generalized Scherk-Schwarz reduction ansatz for the full supersymmetric exceptional field theory in terms of group valued twist matrices subject to consistency equations. With this ansatz the field equations precisely reduce to those of lower-dimensional gauged supergravity parametrized by an embedding tensor. We explicitly construct a family of twist matrices as solutions of the consistency equations. They induce gauged supergravities with gauge groups SO(p,q) and CSO(p,q,r). Geometrically, they describe compactifications on internal spaces given by spheres and (warped) hyperboloides H{sup p,q}, thus extending the applicability of generalized Scherk-Schwarz reductions beyond homogeneous spaces. Together with the dictionary that relates exceptional field theory to D=11 and IIB supergravity, respectively, the construction defines an entire new family of consistent truncations of the original theories. These include not only compactifications on spheres of different dimensions (such as AdS{sub 5}×S{sup 5}), but also various hyperboloid compactifications giving rise to a higher-dimensional embedding of supergravities with non-compact and non-semisimple gauge groups.

  5. TRANSPORT CONTRACT - EXCEPTION TO THE RELATIVITY EFFECTS OF LEGAL DOCUMENT

    Directory of Open Access Journals (Sweden)

    Adriana Elena Belu

    2016-11-01

    Full Text Available The parts to the contract are the shipper freight and the carrier. But the beneficiary of the contract is the conignee, although he doesn’t take part to the signing of the contract, he is (if he is adhering to the contract acquirer of rights and obligations which result from the contract of carriage. The contract of carriage is considered an exception to the principle of relativity effects of the legal act and it is considered by some authors in the literature as a stipulation for another with certain features. Stipulation for another is the contract whereby one part (stipulate provide that the other side (promisor to give, to do or not to do something for the benefit of a third person (beneficiary who do not participate, and he doesn’t take part to the conclusion of the contract. It is considered the only real exception of the principle of relativity. Called contract for another's benefit, stipulation for another creates for the beneficiary third-part right, directly and immediately created in his benefit since the conclusion of the contract between the promisor and the stipulate. The right is created from the time of signing the contract, in the patrimony of beneficiary, regardless of beneficiary’s accepting or waivering this right.

  6. Characterizing interactions in online social networks during exceptional events

    Science.gov (United States)

    Omodei, Elisa; De Domenico, Manlio; Arenas, Alex

    2015-08-01

    Nowadays, millions of people interact on a daily basis on online social media like Facebook and Twitter, where they share and discuss information about a wide variety of topics. In this paper, we focus on a specific online social network, Twitter, and we analyze multiple datasets each one consisting of individuals' online activity before, during and after an exceptional event in terms of volume of the communications registered. We consider important events that occurred in different arenas that range from policy to culture or science. For each dataset, the users' online activities are modeled by a multilayer network in which each layer conveys a different kind of interaction, specifically: retweeting, mentioning and replying. This representation allows us to unveil that these distinct types of interaction produce networks with different statistical properties, in particular concerning the degree distribution and the clustering structure. These results suggests that models of online activity cannot discard the information carried by this multilayer representation of the system, and should account for the different processes generated by the different kinds of interactions. Secondly, our analysis unveils the presence of statistical regularities among the different events, suggesting that the non-trivial topological patterns that we observe may represent universal features of the social dynamics on online social networks during exceptional events.

  7. Diversity as Polyphony

    DEFF Research Database (Denmark)

    Trittin, Hannah; Schoeneborn, Dennis

    2017-01-01

    of organizational members in terms of individual-bound criteria (e.g., gender, age, or ethnicity). By drawing on Bakhtin's notion of polyphony as well as the 'communicative constitution of organizations' (CCO) perspective, we suggest reconsidering diversity as the plurality of 'voices' which can be understood......In this paper, we propose reconceptualizing diversity management from a communication-centered perspective. We base our proposal on the observation that the literature on diversity management, both in the instrumental and critical traditions, is primarily concerned with fostering the diversity...... as the range of individual opinions and societal discourses that get expressed and can find resonance in organizational settings. We contribute to the literature on diversity management by moving away from a focus on individual-bound and inalterable criteria of diversity and toward a reconceptualization...

  8. Exemption, exception and other criteria for transport criticality safety

    International Nuclear Information System (INIS)

    Mennerdahl, D.

    2004-01-01

    Many strange concepts, requirements and specifications related to criticality safety are present in the Regulations. Some earlier problems have been corrected but, going back to 1961 and the first edition of the Regulations, it seems as many changes have been to the worse. Fissile material was defined correctly as a material that could consist of or contain fissile nuclides. Materials consisting of pure fissile nuclides don't exist but are important in package designs. 238 Pu was included as a fissile nuclide only as an emergency, because there was no alternative, but this caused some people to think that all nuclides supporting criticality are fissile. Neutron interaction between different (non-identical) packages had to be evaluated, making the transport index or allowable number of packages a credible safety control. That is not true anymore. The 15 gram exception limit for fissile nuclides was combined with a transport mode limit, similar to but more restrictive than the current consignment limit. The confinement system was introduced to help with formulation of a single requirement for safety of the containment system but is becoming something very different. Controls before the first use of a packaging have become controls of the first use of a package, supporting multiple shipments of the same package. The lack of exemption limits for fissile material essentially makes all radioactive materials fissile (all radioactive material contains some fissile atoms). Radioactive material seems to be defined without consideration of the criticality hazard of the material. LSA materials are defined with consideration of criticality, but only relates to quantities in fissile exceptions when other properties can be equally or more important. In July 2004, a number of proposals to IAEA have been submitted by Sweden to improve and expand the criticality safety control of the Regulations. Essential is the introduction of the fissionable nuclide and material concepts in

  9. Exemption, exception and other criteria for transport criticality safety

    Energy Technology Data Exchange (ETDEWEB)

    Mennerdahl, D. [E Mennerdahl Systems, Taeby (Sweden)

    2004-07-01

    Many strange concepts, requirements and specifications related to criticality safety are present in the Regulations. Some earlier problems have been corrected but, going back to 1961 and the first edition of the Regulations, it seems as many changes have been to the worse. Fissile material was defined correctly as a material that could consist of or contain fissile nuclides. Materials consisting of pure fissile nuclides don't exist but are important in package designs. {sup 238}Pu was included as a fissile nuclide only as an emergency, because there was no alternative, but this caused some people to think that all nuclides supporting criticality are fissile. Neutron interaction between different (non-identical) packages had to be evaluated, making the transport index or allowable number of packages a credible safety control. That is not true anymore. The 15 gram exception limit for fissile nuclides was combined with a transport mode limit, similar to but more restrictive than the current consignment limit. The confinement system was introduced to help with formulation of a single requirement for safety of the containment system but is becoming something very different. Controls before the first use of a packaging have become controls of the first use of a package, supporting multiple shipments of the same package. The lack of exemption limits for fissile material essentially makes all radioactive materials fissile (all radioactive material contains some fissile atoms). Radioactive material seems to be defined without consideration of the criticality hazard of the material. LSA materials are defined with consideration of criticality, but only relates to quantities in fissile exceptions when other properties can be equally or more important. In July 2004, a number of proposals to IAEA have been submitted by Sweden to improve and expand the criticality safety control of the Regulations. Essential is the introduction of the fissionable nuclide and material

  10. Diversity does not travel!

    DEFF Research Database (Denmark)

    Lund, Rebecca; Meriläinen, Susan; Tienari, Janne

    2013-01-01

    In this chapter we offer insights into the social construction of diversity in Finnish organizations and society. In Finnish organizations, gender is highlighted while other markers of diversity are blotted out. 'Non-Finns' become subject to cultural assimilation. The US-based concept of Diversit...... Management becomes adopted and adapted in particular ways. Standardized concepts of diversity and its management do not travel, rather they become translated locally. In organizational practice, globalization is slow and laborious....

  11. Diversity in marketing practice

    OpenAIRE

    Torres, Ann Marie

    2009-01-01

    Theory development in marketing has received periodic debate. In the spirit of reappraisal, this thesis endeavours to explain the nature of diversity in marketing practice found among firms and the manner in which marketing practice is related to organisational performance. The specific research goals are to explore: the nature of diversity in marketing practice, as linked to strategic archetypes; whether there is evidence of order in the diversity of marketing practice that can be linked to ...

  12. Petroleum-influenced beach sediments of the campeche bank, Mexico: Diversity and bacterial community structure assessment

    Energy Technology Data Exchange (ETDEWEB)

    Rosano-Hernandez, M. C.; Ramirez-Saad, H.; Fernandez-Linares, L.; Xoconostle, B.

    2009-07-01

    In Mexican, either spilled or seeped out petroleum impacts nearly 300 km of the beach between Dos Bocas (Tabasco State) to Champoton town (Campeche State), where between 9 to exceptionally 9 to exceptionally 300 tonnes of oil as tar balls have been measured. This study was focused to explore, for the first time, the bacterial diversity and community structure ({alpha}-diversity)- in a kilometric scale on petroleum influenced sediments of 100 km of sandy beach. (Author)

  13. Petroleum-influenced beach sediments of the campeche bank, Mexico: Diversity and bacterial community structure assessment

    International Nuclear Information System (INIS)

    Rosano-Hernandez, M. C.; Ramirez-Saad, H.; Fernandez-Linares, L.; Xoconostle, B.

    2009-01-01

    In Mexican, either spilled or seeped out petroleum impacts nearly 300 km of the beach between Dos Bocas (Tabasco State) to Champoton town (Campeche State), where between 9 to exceptionally 9 to exceptionally 300 tonnes of oil as tar balls have been measured. This study was focused to explore, for the first time, the bacterial diversity and community structure (α-diversity)- in a kilometric scale on petroleum influenced sediments of 100 km of sandy beach. (Author)

  14. Bacillus subtilis genome diversity.

    Science.gov (United States)

    Earl, Ashlee M; Losick, Richard; Kolter, Roberto

    2007-02-01

    Microarray-based comparative genomic hybridization (M-CGH) is a powerful method for rapidly identifying regions of genome diversity among closely related organisms. We used M-CGH to examine the genome diversity of 17 strains belonging to the nonpathogenic species Bacillus subtilis. Our M-CGH results indicate that there is considerable genetic heterogeneity among members of this species; nearly one-third of Bsu168-specific genes exhibited variability, as measured by the microarray hybridization intensities. The variable loci include those encoding proteins involved in antibiotic production, cell wall synthesis, sporulation, and germination. The diversity in these genes may reflect this organism's ability to survive in diverse natural settings.

  15. River Diversions and Shoaling

    National Research Council Canada - National Science Library

    Letter, Jr., Joseph V; Pinkard, Jr., C. F; Raphelt, Nolan K

    2008-01-01

    This Coastal and Hydraulics Engineering Technical Note describes the current knowledge of the potential impacts of river diversions on channel morphology, especially induced sedimentation in the river channel...

  16. Superior optical nonlinearity of an exceptional fluorescent stilbene dye

    Energy Technology Data Exchange (ETDEWEB)

    He, Tingchao [College of Physics Science and Technology, Shenzhen University, Shenzhen 518060 (China); Division of Physics and Applied Physics, Centre for Disruptive Photonic Technologies (CDPT), School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore); Sreejith, Sivaramapanicker; Zhao, Yanli [Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore); Gao, Yang; Grimsdale, Andrew C. [School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore 639798 (Singapore); Lin, Xiaodong, E-mail: linxd@szu.edu.cn, E-mail: hdsun@ntu.edu.sg [College of Physics Science and Technology, Shenzhen University, Shenzhen 518060 (China); Sun, Handong, E-mail: linxd@szu.edu.cn, E-mail: hdsun@ntu.edu.sg [Division of Physics and Applied Physics, Centre for Disruptive Photonic Technologies (CDPT), School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 (Singapore)

    2015-03-16

    Strong multiphoton absorption and harmonic generation in organic fluorescent chromophores are, respectively, significant in many fields of research. However, most of fluorescent chromophores fall short of the full potential due to the absence of the combination of such different nonlinear upconversion behaviors. Here, we demonstrate that an exceptional fluorescent stilbene dye could exhibit efficient two- and three-photon absorption under the excitation of femtosecond pulses in solution phase. Benefiting from its biocompatibility and strong excited state absorption behavior, in vitro two-photon bioimaging and superior optical limiting have been exploited, respectively. Simultaneously, the chromophore could generate efficient three-photon excited fluorescence and third-harmonic generation (THG) when dispersed into PMMA film, circumventing the limitations of classical fluorescent chromophores. Such chromophore may find application in the production of coherent light sources of higher photon energy. Moreover, the combination of three-photon excited fluorescence and THG can be used in tandem to provide complementary information in biomedical studies.

  17. Exceptional memory performance in the Long Life Family Study

    DEFF Research Database (Denmark)

    Barral, Sandra; Cosentino, Stephanie; Costa, Rosann

    2013-01-01

    Research to understand variability at the highest end of the cognitive performance distribution has been scarce. Our aim was to define a cognitive endophenotype based on exceptional episodic memory (EM) performance and to investigate familial aggregation of EM in families from the Long Life Family...... Study (LLFS). Using a sample of 1911 nondemented offspring of long-lived probands, we created a quantitative phenotype, EM (memory z ≥ 1.5), and classified LLFS families as EM and non-EM families based on the number of EM offspring. We then assessed differences in memory performance between LLFS...... = 1.4 × 10(-4)). We demonstrated that there is a familial correlation of the EM endophenotype, suggesting that genetic variants might influence memory performance in long-lived families....

  18. Election and Exceptions – The Danish Fine Count

    DEFF Research Database (Denmark)

    Vadgård, Anne Kathrine Pihl

    In this paper I explore the role of the Danish election law in the conduct of elections. Based on 9 months of ethnographic fieldwork in an election office in a Danish municipality, I focus on the conflicting relation between the legal framework and deviating election practices. I argue that handl......In this paper I explore the role of the Danish election law in the conduct of elections. Based on 9 months of ethnographic fieldwork in an election office in a Danish municipality, I focus on the conflicting relation between the legal framework and deviating election practices. I argue...... that handling of such election practices requires thoughtful and vigorous bureaucratic work. Thus the election law may be said to act as a navigational tool throughout the complex bureaucratic practices of planning an election. Yet exceptions to the law inevitably occur on Election Day, requiring bending...

  19. EXCEPTIONAL POINTS IN OPEN AND PT-SYMMETRIC SYSTEMS

    Directory of Open Access Journals (Sweden)

    Hichem Eleuch

    2014-04-01

    Full Text Available Exceptional points (EPs determine the dynamics of open quantum systems and cause also PT symmetry breaking in PT symmetric systems. From a mathematical point of view, this is caused by the fact that the phases of the wavefunctions (eigenfunctions of a non-Hermitian Hamiltonian relative to one another are not rigid when an EP is approached. The system is therefore able to align with the environment to which it is coupled and, consequently, rigorous changes of the system properties may occur. We compare analytically as well as numerically the eigenvalues and eigenfunctions of a 2 × 2 matrix that is characteristic either of open quantum systems at high level density or of PT symmetric optical lattices. In both cases, the results show clearly the influence of the environment on the system in the neighborhood of EPs. Although the systems are very different from one another, the eigenvalues and eigenfunctions indicate the same characteristic features.

  20. General theory of spontaneous emission near exceptional points.

    Science.gov (United States)

    Pick, Adi; Zhen, Bo; Miller, Owen D; Hsu, Chia W; Hernandez, Felipe; Rodriguez, Alejandro W; Soljačić, Marin; Johnson, Steven G

    2017-05-29

    We present a general theory of spontaneous emission at exceptional points (EPs)-exotic degeneracies in non-Hermitian systems. Our theory extends beyond spontaneous emission to any light-matter interaction described by the local density of states (e.g., absorption, thermal emission, and nonlinear frequency conversion). Whereas traditional spontaneous-emission theories imply infinite enhancement factors at EPs, we derive finite bounds on the enhancement, proving maximum enhancement of 4 in passive systems with second-order EPs and significantly larger enhancements (exceeding 400×) in gain-aided and higher-order EP systems. In contrast to non-degenerate resonances, which are typically associated with Lorentzian emission curves in systems with low losses, EPs are associated with non-Lorentzian lineshapes, leading to enhancements that scale nonlinearly with the resonance quality factor. Our theory can be applied to dispersive media, with proper normalization of the resonant modes.

  1. The savant syndrome: intellectual impairment and exceptional skill.

    Science.gov (United States)

    Miller, L K

    1999-01-01

    Occasionally, people with developmental disability display skills at a level inconsistent with their general intellectual functioning, so-called "savant" behavior. Studies of savant behavior are reviewed to determine their relevance to notions about the importance of general intellective functions in the development of exceptional skill. It is concluded that (a) the skill exhibited by savants shares many characteristics with that in people without disability, (b) the skill is usually accompanied by normative levels of performance on at least some subtests of standardized measures of cognitive achievement, and (c) it is unclear whether savants have distinctive cognitive strengths or motivational dispositions, though their relative prevalence among people with certain kinds of disability suggests predisposing constraints. The author proposes that these skills typically reflect highly elaborated preconceptual representational systems.

  2. Observation of the exceptional point in cavity magnon-polaritons.

    Science.gov (United States)

    Zhang, Dengke; Luo, Xiao-Qing; Wang, Yi-Pu; Li, Tie-Fu; You, J Q

    2017-11-08

    Magnon-polaritons are hybrid light-matter quasiparticles originating from the strong coupling between magnons and photons. They have emerged as a potential candidate for implementing quantum transducers and memories. Owing to the dampings of both photons and magnons, the polaritons have limited lifetimes. However, stationary magnon-polariton states can be reached by a dynamical balance between pumping and losses, so the intrinsically nonequilibrium system may be described by a non-Hermitian Hamiltonian. Here we design a tunable cavity quantum electrodynamics system with a small ferromagnetic sphere in a microwave cavity and engineer the dissipations of photons and magnons to create cavity magnon-polaritons which have non-Hermitian spectral degeneracies. By tuning the magnon-photon coupling strength, we observe the polaritonic coherent perfect absorption and demonstrate the phase transition at the exceptional point. Our experiment offers a novel macroscopic quantum platform to explore the non-Hermitian physics of the cavity magnon-polaritons.

  3. EXCEPTIONALLY RARE VARIANTS OF THE URINARY SYSTEM ANOMALIES - ROENTGEN PRESENTATION

    Directory of Open Access Journals (Sweden)

    Rade R. Babić

    2002-07-01

    Full Text Available The results of the radiological study of the urinary system anomalies are presented on the material consisting of 8,568 urographies done from 1990 to 2001 at the Institute for Radiology, Niš. The paper shows exceptionally rare anomalies of the urinary system: a horse-shoe shaped kidney with pyelocaliceal systems in its arms and isthmus, heterolateral ectopia of the kidney with fusion, abdominal-medial ectopia of the kidney with ventral malrotation and cup hyperplasia, hypoplastic cup, triple pyeolcaliceal system, M. Lenarduzzi and blind-ending of the Y-shaped urethra. The author concludes that, for the sake of performing every day professional work, it is necessary to possess detailed knowledge of the rarest urinary system anomalies.

  4. Reduced prevalence of cognitive impairment in families with exceptional longevity

    DEFF Research Database (Denmark)

    Cosentino, Stephanie; Schupf, Nicole; Christensen, Kaare

    2013-01-01

    with exceptional longevity are protected against cognitive impairment consistent with Alzheimer disease. DESIGN Cross-sectional analysis. SETTING Multisite study in New York, Massachusetts, Pennsylvania, and Denmark. PARTICIPANTS A total of 1870 individuals (1510 family members and 360 spouse controls) recruited...... through the Long Life Family Study. MAIN OUTCOME AND MEASURE Prevalence of cognitive impairment based on a diagnostic algorithm validated using the National Alzheimer's Coordinating Center data set. RESULTS The cognitive algorithm classified 546 individuals (38.5%) as having cognitive impairment...... consistent with Alzheimer disease. Long Life Family Study probands had a slightly but not statistically significant reduced risk of cognitive impairment compared with spouse controls (121 of 232 for probands vs 45 of 103 for spouse controls; odds ratio = 0.7; 95% CI, 0.4-1.4), whereas Long Life Family Study...

  5. The exceptional ethics of the investigator-subject relationship.

    Science.gov (United States)

    Sachs, Benjamin

    2010-02-01

    This article concerns the validity of six canonical rules that institutional review boards use to constrain the behavior of investigators. These rules require investigators to design their studies in a scientifically valid way, not pay their subjects to take risks, minimize risks to their subjects, secure for their subjects access to effective interventions post-trial, not pay their subjects too much and allow their subjects to withdraw from the study unconditionally. Enforcement of these rules is problematic because there are other relationships that seem to be like the investigator-subject relationship in all ethically relevant respects, such as the employer-employee and volunteer organizer-volunteer relationships, to which we would not dream of applying these same rules. Applying these rules in one context but not the others is a violation of ethical consistency I label "exceptionalism." We should conclude that it is time to reexamine the validity of the six rules.

  6. Determinants of Household Savings in Turkey Except for Income

    Directory of Open Access Journals (Sweden)

    Mehmet ŞENGÜR

    2016-01-01

    Full Text Available Household has an extremely important place in the division of income for the economies. It plays a decisive role in personal consumption, investment, and savings. This study aims to identify the determinants of household savings except for income. In this study, "Household Budget Survey" conducted by Turkish Statistical Institute for the years 2002-2013 is used. Survey data has been analyzed by logistic regression models. The results of the study show that house ownership, having an extra house, having annual disposable income of over 10.000 ₺, education level also have a positive effect on household savings. On the other hand, the number of family members, car ownership, temporary or seasonal employment, and living in rural areas affect household savings in a negative way.

  7. Exceptional preservation of Miocene pollen: plasmolysis captured in salt?

    Energy Technology Data Exchange (ETDEWEB)

    Durska, W.

    2016-07-01

    Exceptionally well-preserved Miocene pollen from the Bochnia salt mine of southern Poland is reported herein. The halite deposits within the salt mine belonging to Late Badenian (Miocene) marine evaporites originated in the Paratethys. Rounded and angular structures are present inside pollen grains. On the basis of the similarity with plasmolyzed pollen grains of modern plants, these structures are considered to represent cytoplasms plasmolyzed in the condensed brine prior to fossilization. Two forms of plasmolyzed cytoplasms (concave and convex) can be observed in modern pollen. Both are distinguished in the investigated fossil material. In porate and colporate grains the shape of the plasmolyzed cellular content is concave while in inaperturate it is convex. The plasmolysis form depends on the type of apertures and pollen shape. The percentage of pollen with fossilized cytoplasms within individual taxa is a valuable environmental indicator, as it depends on the proximity of the pollen-producing plant assemblages to the depositional setting. (Author)

  8. A Short-Range Distance Sensor with Exceptional Linearity

    Science.gov (United States)

    Simmons, Steven; Youngquist, Robert

    2013-01-01

    A sensor has been demonstrated that can measure distance over a total range of about 300 microns to an accuracy of about 0.1 nm (resolution of about 0.01 nm). This represents an exceptionally large dynamic range of operation - over 1,000,000. The sensor is optical in nature, and requires the attachment of a mirror to the object whose distance is being measured. This work resulted from actively developing a white light interferometric system to be used to measure the depths of defects in the Space Shuttle Orbiter windows. The concept was then applied to measuring distance. The concept later expanded to include spectrometer calibration. In summary, broadband (i.e., white) light is launched into a Michelson interferometer, one mirror of which is fixed and one of which is attached to the object whose distance is to be measured. The light emerging from the interferometer has traveled one of two distances: either the distance to the fixed mirror and back, or the distance to the moving mirror and back. These two light beams mix and produce an interference pattern where some wavelengths interfere constructively and some destructively. Sending this light into a spectrometer allows this interference pattern to be analyzed, yielding the net distance difference between the two paths. The unique feature of this distance sensor is its ability to measure accurately distance over a dynamic range of more than one million, the ratio of its range (about 300 microns) to its accuracy (about 0.1 nanometer). Such a large linear operating range is rare and arises here because both amplitude and phase-matching algorithms contribute to the performance. The sensor is limited by the need to attach a mirror of some kind to the object being tracked, and by the fairly small total range, but the exceptional dynamic range should make it of interest.

  9. Phase diagrams of exceptional and supersymmetric lattice gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Wellegehausen, Bjoern-Hendrik

    2012-07-10

    In this work different strongly-coupled gauge theories with and without fundamental matter have been studied on the lattice with an emphasis on the confinement problem and the QCD phase diagram at nonvanishing net baryon density as well as on possible supersymmetric extensions of the standard model of particle physics. In gauge theories with a non-trivial centre symmetry, as for instance SU(3)-Yang-Mills theory, confinement is intimately related to the centre of the gauge group, and the Polyakov loop serves as an order parameter for confinement. In QCD, this centre symmetry is explicitly broken by quarks in the fundamental representation of the gauge group. But still quarks and gluons are confined in mesons, baryons and glueballs at low temperatures and small densities, suggesting that centre symmetry is not responsible for the phenomenon of confinement. Therefore it is interesting to study pure gauge theories without centre symmetry. In this work this has been done by replacing the gauge group SU(3) of the strong interaction with the exceptional Lie group G{sub 2}, that has a trivial centre. To investigate G{sub 2} gauge theory on the lattice, a new and highly efficient update algorithm has been developed, based on a local HMC algorithm. Employing this algorithm, the proposed and already investigated first order phase transition from a confined to a deconfined phase has been confirmed, showing that indeed a first order phase transition without symmetry breaking or an order parameter is possible. In this context, also the deconfinement phase transition of the exceptional Lie groups F4 and E6 in three spacetime dimensions has been studied. It has been shown that both theories also possess a first order phase transition.

  10. Phase diagrams of exceptional and supersymmetric lattice gauge theories

    International Nuclear Information System (INIS)

    Wellegehausen, Bjoern-Hendrik

    2012-01-01

    In this work different strongly-coupled gauge theories with and without fundamental matter have been studied on the lattice with an emphasis on the confinement problem and the QCD phase diagram at nonvanishing net baryon density as well as on possible supersymmetric extensions of the standard model of particle physics. In gauge theories with a non-trivial centre symmetry, as for instance SU(3)-Yang-Mills theory, confinement is intimately related to the centre of the gauge group, and the Polyakov loop serves as an order parameter for confinement. In QCD, this centre symmetry is explicitly broken by quarks in the fundamental representation of the gauge group. But still quarks and gluons are confined in mesons, baryons and glueballs at low temperatures and small densities, suggesting that centre symmetry is not responsible for the phenomenon of confinement. Therefore it is interesting to study pure gauge theories without centre symmetry. In this work this has been done by replacing the gauge group SU(3) of the strong interaction with the exceptional Lie group G 2 , that has a trivial centre. To investigate G 2 gauge theory on the lattice, a new and highly efficient update algorithm has been developed, based on a local HMC algorithm. Employing this algorithm, the proposed and already investigated first order phase transition from a confined to a deconfined phase has been confirmed, showing that indeed a first order phase transition without symmetry breaking or an order parameter is possible. In this context, also the deconfinement phase transition of the exceptional Lie groups F4 and E6 in three spacetime dimensions has been studied. It has been shown that both theories also possess a first order phase transition.

  11. The Bangladesh paradox: exceptional health achievement despite economic poverty.

    Science.gov (United States)

    Chowdhury, A Mushtaque R; Bhuiya, Abbas; Chowdhury, Mahbub Elahi; Rasheed, Sabrina; Hussain, Zakir; Chen, Lincoln C

    2013-11-23

    Bangladesh, the eighth most populous country in the world with about 153 million people, has recently been applauded as an exceptional health performer. In the first paper in this Series, we present evidence to show that Bangladesh has achieved substantial health advances, but the country's success cannot be captured simplistically because health in Bangladesh has the paradox of steep and sustained reductions in birth rate and mortality alongside continued burdens of morbidity. Exceptional performance might be attributed to a pluralistic health system that has many stakeholders pursuing women-centred, gender-equity-oriented, highly focused health programmes in family planning, immunisation, oral rehydration therapy, maternal and child health, tuberculosis, vitamin A supplementation, and other activities, through the work of widely deployed community health workers reaching all households. Government and non-governmental organisations have pioneered many innovations that have been scaled up nationally. However, these remarkable achievements in equity and coverage are counterbalanced by the persistence of child and maternal malnutrition and the low use of maternity-related services. The Bangladesh paradox shows the net outcome of successful direct health action in both positive and negative social determinants of health--ie, positives such as women's empowerment, widespread education, and mitigation of the effect of natural disasters; and negatives such as low gross domestic product, pervasive poverty, and the persistence of income inequality. Bangladesh offers lessons such as how gender equity can improve health outcomes, how health innovations can be scaled up, and how direct health interventions can partly overcome socioeconomic constraints. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. The interplay of diversity training and diversity beliefs on team creativity in nationality diverse teams

    NARCIS (Netherlands)

    Homan, A.C.; Buengeler, C.; Eckhoff, R.A.; van Ginkel, W.P.; Voelpel, S.C.

    2015-01-01

    Attaining value from nationality diversity requires active diversity management, which organizations often employ in the form of diversity training programs. Interestingly, however, the previously reported effects of diversity training are often weak and, sometimes, even negative. This situation

  13. Complex Systems Analysis of Cell Cycling Models in Carcinogenesis:II. Cell Genome and Interactome, Neoplastic Non-random Transformation Models in Topoi with Lukasiewicz-Logic and MV Algebras

    CERN Document Server

    Baianu, I C

    2004-01-01

    Quantitative Biology, abstract q-bio.OT/0406045 From: I.C. Baianu Dr. [view email] Date (v1): Thu, 24 Jun 2004 02:45:13 GMT (164kb) Date (revised v2): Fri, 2 Jul 2004 00:58:06 GMT (160kb) Complex Systems Analysis of Cell Cycling Models in Carcinogenesis: II. Authors: I.C. Baianu Comments: 23 pages, 1 Figure Report-no: CC04 Subj-class: Other Carcinogenesis is a complex process that involves dynamically inter-connected modular sub-networks that evolve under the influence of micro-environmentally induced perturbations, in non-random, pseudo-Markov chain processes. An appropriate n-stage model of carcinogenesis involves therefore n-valued Logic treatments of nonlinear dynamic transformations of complex functional genomes and cell interactomes. Lukasiewicz Algebraic Logic models of genetic networks and signaling pathways in cells are formulated in terms of nonlinear dynamic systems with n-state components that allow for the generalization of previous, Boolean or "fuzzy", logic models of genetic activities in vivo....

  14. Evaluation of physical activity interventions in children via the reach, efficacy/effectiveness, adoption, implementation, and maintenance (RE-AIM) framework: A systematic review of randomized and non-randomized trials.

    Science.gov (United States)

    McGoey, Tara; Root, Zach; Bruner, Mark W; Law, Barbi

    2016-01-01

    Existing reviews of physical activity (PA) interventions designed to increase PA behavior exclusively in children (ages 5 to 11years) focus primarily on the efficacy (e.g., internal validity) of the interventions without addressing the applicability of the results in terms of generalizability and translatability (e.g., external validity). This review used the RE-AIM (Reach, Efficacy/Effectiveness, Adoption, Implementation, Maintenance) framework to measure the degree to which randomized and non-randomized PA interventions in children report on internal and external validity factors. A systematic search for controlled interventions conducted within the past 12years identified 78 studies that met the inclusion criteria. Based on the RE-AIM criteria, most of the studies focused on elements of internal validity (e.g., sample size, intervention location and efficacy/effectiveness) with minimal reporting of external validity indicators (e.g., representativeness of participants, start-up costs, protocol fidelity and sustainability). Results of this RE-AIM review emphasize the need for future PA interventions in children to report on real-world challenges and limitations, and to highlight considerations for translating evidence-based results into health promotion practice. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Impact of a Multifaceted and Clinically Integrated Training Program in Evidence-Based Practice on Knowledge, Skills, Beliefs and Behaviour among Clinical Instructors in Physiotherapy: A Non-Randomized Controlled Study.

    Science.gov (United States)

    Olsen, Nina Rydland; Bradley, Peter; Espehaug, Birgitte; Nortvedt, Monica Wammen; Lygren, Hildegunn; Frisk, Bente; Bjordal, Jan Magnus

    2015-01-01

    Physiotherapists practicing at clinical placement sites assigned the role as clinical instructors (CIs), are responsible for supervising physiotherapy students. For CIs to role model evidence-based practice (EBP) they need EBP competence. The aim of this study was to assess the short and long term impact of a six-month multifaceted and clinically integrated training program in EBP on the knowledge, skills, beliefs and behaviour of CIs supervising physiotherapy students. We invited 37 CIs to participate in this non-randomized controlled study. Three self-administered questionnaires were used pre- and post-intervention, and at six-month follow-up: 1) The Adapted Fresno test (AFT), 2) the EBP Belief Scale and 3) the EBP Implementation Scale. The analysis approach was linear regression modeling using Generalized Estimating Equations. In total, 29 CIs agreed to participate in the study: 14 were invited to participate in the intervention group and 15 were invited to participate in the control group. One in the intervention group and five in the control group were lost to follow-up. At follow-up, the group difference was statistically significant for the AFT (mean difference = 37, 95% CI (15.9 -58.1), p students.

  16. EFFICACY AND SAFETY OF INHALED NITRIC OXIDE USE IN PATIENTS WITH PULMONARY HYPERTENSION AND CHRONIC HEART FAILURE III-IV FUNCTIONAL CLASS, SURVIVED LEFT VENTRICULAR MYOCARDIAL INFARCTION: RESULTS OF NON-RANDOMIZED COMAPARIVE STUDY

    Directory of Open Access Journals (Sweden)

    P. N. Pavlenko

    2011-01-01

    Full Text Available Aim – assessment of the influence of inhaled nitric oxide (NO on the course of pulmonary hypertension (PH in patients with chronic heartfailure (CHF III–IV functional class (FC, myocardial infarction (MI.Materials and methods. Results of comparative non-randomized study that included 45 patients (26 men and 19 women aged 51 to 98 years with PH III–IV functional class, left ventricular myocardial infarction. In the study, patients underwent physical examination and Doppler echocardiography, and assessed FC LH (carried out with six-minute walking test, to determine the degree of dyspnea by Borg.Results. Symptoms of CHF and PH regressed in both groups of patients against the background of the therapy. Conclusion. It is established that the use of inhaled NO is a safe therapy and helps to reduce mean pulmonary arterial pressure (PAPmean in patients with PH and CHF III–IV FC, myocardial infarction. The method of inhaled NO is simple and easy to use.

  17. EFFICACY AND SAFETY OF INHALED NITRIC OXIDE USE IN PATIENTS WITH PULMONARY HYPERTENSION AND CHRONIC HEART FAILURE III-IV FUNCTIONAL CLASS, SURVIVED LEFT VENTRICULAR MYOCARDIAL INFARCTION: RESULTS OF NON-RANDOMIZED COMAPARIVE STUDY

    Directory of Open Access Journals (Sweden)

    P. N. Pavlenko

    2014-07-01

    Full Text Available Aim – assessment of the influence of inhaled nitric oxide (NO on the course of pulmonary hypertension (PH in patients with chronic heartfailure (CHF III–IV functional class (FC, myocardial infarction (MI.Materials and methods. Results of comparative non-randomized study that included 45 patients (26 men and 19 women aged 51 to 98 years with PH III–IV functional class, left ventricular myocardial infarction. In the study, patients underwent physical examination and Doppler echocardiography, and assessed FC LH (carried out with six-minute walking test, to determine the degree of dyspnea by Borg.Results. Symptoms of CHF and PH regressed in both groups of patients against the background of the therapy. Conclusion. It is established that the use of inhaled NO is a safe therapy and helps to reduce mean pulmonary arterial pressure (PAPmean in patients with PH and CHF III–IV FC, myocardial infarction. The method of inhaled NO is simple and easy to use.

  18. RANDOMNESS of Numbers DEFINITION(QUERY:WHAT? V HOW?) ONLY Via MAXWELL-BOLTZMANN CLASSICAL-Statistics(MBCS) Hot-Plasma VS. Digits-Clumping Log-Law NON-Randomness Inversion ONLY BOSE-EINSTEIN QUANTUM-Statistics(BEQS) .

    Science.gov (United States)

    Siegel, Z.; Siegel, Edward Carl-Ludwig

    2011-03-01

    RANDOMNESS of Numbers cognitive-semantics DEFINITION VIA Cognition QUERY: WHAT???, NOT HOW?) VS. computer-``science" mindLESS number-crunching (Harrel-Sipser-...) algorithmics Goldreich "PSEUDO-randomness"[Not.AMS(02)] mea-culpa is ONLY via MAXWELL-BOLTZMANN CLASSICAL-STATISTICS(NOT FDQS!!!) "hot-plasma" REPULSION VERSUS Newcomb(1881)-Weyl(1914;1916)-Benford(1938) "NeWBe" logarithmic-law digit-CLUMPING/ CLUSTERING NON-Randomness simple Siegel[AMS Joint.Mtg.(02)-Abs. # 973-60-124] algebraic-inversion to THE QUANTUM and ONLY BEQS preferentially SEQUENTIALLY lower-DIGITS CLUMPING/CLUSTERING with d = 0 BEC, is ONLY VIA Siegel-Baez FUZZYICS=CATEGORYICS (SON OF TRIZ)/"Category-Semantics"(C-S), latter intersection/union of Lawvere(1964)-Siegel(1964)] category-theory (matrix: MORPHISMS V FUNCTORS) "+" cognitive-semantics'' (matrix: ANTONYMS V SYNONYMS) yields Siegel-Baez FUZZYICS=CATEGORYICS/C-S tabular list-format matrix truth-table analytics: MBCS RANDOMNESS TRUTH/EMET!!!

  19. Relationship of nocturnal concentrations of melatonin, gamma-aminobutyric acid and total antioxidants in peripheral blood with insomnia after stroke: study protocol for a prospective non-randomized controlled trial

    Institute of Scientific and Technical Information of China (English)

    Wei Zhang; Fang Li; Tong Zhang

    2017-01-01

    Melatonin and gamma-aminobutyric acid (GABA) have been shown to regulate sleep. The nocturnal concentrations of melatonin, GABA and total antioxidants may relate to insomnia in stroke patients. In this prospective single-center non-randomized controlled clinical trial performed in the China Rehabilitation Research Center, we analyzed the relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke. Patients during rehabilitation of stroke were recruited and assigned to the insomnia group or non-insomnia group. Simultaneously, persons without stroke or insomnia served as normal controls. Each group contained 25 cases. The primary outcome was nocturnal concentrations of melatonin, GABA and total antioxidants in peripheral blood. The secondary outcomes were Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, Fatigue Severity Scale, Morningness-Eveningness Questionnaire (Chinese version), and National Institute of Health Stroke Scale. The relationship of nocturnal concentrations of melatonin, GABA and total antioxidants with insomnia after stroke was analyzed and showed that they were lower in the insomnia group than in the non-insomnia group. The severity of stroke was higher in the insomnia group than in the non-insomnia group. Correlation analysis demonstrated that the nocturnal concentrations of melatonin and GABA were associated with insomnia after stroke. This trial was regis-tered at ClinicalTrials.gov, identifier: NCT03202121.

  20. The study protocol for a non-randomized controlled clinical trial using a genotype-guided strategy in a dataset of patients who undergone percutaneous coronary intervention with stent

    Directory of Open Access Journals (Sweden)

    Cristina Lucía Dávila-Fajardo

    2017-02-01

    Full Text Available This article contains data related to the research article entitled “Results of genotype–guided antiplatelet therapy in patients undergone percutaneous coronary intervention with stent” (J. Sánchez-Ramos, C.L. Dávila-Fajardo, P. Toledo Frías, X. Díaz Villamarín, L.J. Martínez-González, S. Martínez Huertas, F. Burillo Gómez, J. Caballero Borrego, A. Bautista Pavés, M.C. Marín Guzmán, J.A. Ramirez Hernández, C. Correa Vilches, J. Cabeza Barrera, 2016 (1. This data article reports, for the first time, about the non-randomized clinical trial protocol that check if CYP2C19/ABCB1 genotype–guided strategy in which the choice of antiplatelet therapy is based on the genetic test, reduces the rates of cardiovascular events and bleeding compared to a non-tailored strategy in patients undergone percutaneous coronary intervention (PCI with stent. The data included in this article are: design and setting of the study, study population, inclusion and exclusion criteria, definition of the intervention, objectives, variables (baseline characteristics and during the follow-up, study procedures, collection and treatment of the biological sample, genotyping, withdrawal criteria, sample size, statistic analysis, ethical aspects, information sheet and consent form. The authors confirm that this study has been registered in Eudra CT (Eudra CT: 2016-001294-33.

  1. Molecular and functional diversity in Capsicum landraces of ...

    African Journals Online (AJOL)

    shrawan

    2013-09-25

    Sep 25, 2013 ... of diversity in the local germplasm was much needed to recognize the genetic .... reducing sugar and multiplying with a conversion factor (0.95). The absorbance for ..... Except SPG-3 which was outlier with 54% intra-cluster ...

  2. Consumers control diversity and functioning of a natural marine ecosystem.

    Directory of Open Access Journals (Sweden)

    Andrew H Altieri

    Full Text Available BACKGROUND: Our understanding of the functional consequences of changes in biodiversity has been hampered by several limitations of previous work, including limited attention to trophic interactions, a focus on species richness rather than evenness, and the use of artificially assembled communities. METHODOLOGY AND PRINCIPAL FINDINGS: In this study, we manipulated the density of an herbivorous snail in natural tide pools and allowed seaweed communities to assemble in an ecologically relevant and non-random manner. Seaweed species evenness and biomass-specific primary productivity (mg O(2 h(-1 g(-1 were higher in tide pools with snails because snails preferentially consumed an otherwise dominant seaweed species that can reduce biomass-specific productivity rates of algal assemblages. Although snails reduced overall seaweed biomass in tide pools, they did not affect gross primary productivity at the scale of tide pools (mg O(2 h(-1 pool(-1 or mg O(2 h(-1 m(-2 because of the enhanced biomass-specific productivity associated with grazer-mediated increases in algal evenness. SIGNIFICANCE: Our results suggest that increased attention to trophic interactions, diversity measures other than richness, and particularly the effects of consumers on evenness and primary productivity, will improve our understanding of the relationship between diversity and ecosystem functioning and allow more effective links between experimental results and real-world changes in biodiversity.

  3. Ecological partitioning and diversity in tropical planktonic foraminifera

    Directory of Open Access Journals (Sweden)

    Seears Heidi A

    2012-04-01

    Full Text Available Abstract Background Ecological processes are increasingly being viewed as an important mode of diversification in the marine environment, where the high dispersal potential of pelagic organisms, and a lack of absolute barriers to gene flow may limit the occurrence of allopatric speciation through vicariance. Here we focus on the potential role of ecological partitioning in the diversification of a widely distributed group of marine protists, the planktonic foraminifera. Sampling was conducted in the tropical Arabian Sea, during the southwest (summer monsoon, when pronounced environmental conditions result in a strong disparity in temperature, salinity and productivity between distinct northern and southern water masses. Results We uncovered extensive genetic diversity within the Arabian Sea planktonic foraminifera, identifying 13 morphospecies, represented by 20 distinct SSU rRNA genetic types. Several morphospecies/genetic types displayed non-random biogeographical distributions, partitioning between the northern and southern water masses, giving a strong indication of independent ecological adaptations. Conclusions We propose sea-surface primary productivity as the main factor driving the geographical segregation of Arabian Sea planktonic foraminifera, during the SW monsoon, with variations in symbiotic associations possibly playing a role in the specific ecological adaptations observed. Our findings suggest that ecological partitioning could be contributing to the high levels of 'cryptic' genetic diversity observed within the planktonic foraminifera, and support the view that ecological processes may play a key role in the diversification of marine pelagic organisms.

  4. Diversity in Leadership

    Science.gov (United States)

    Beer, Janet

    2015-01-01

    This paper presents a lecture given at the 17th Annual Lecture of the Association of University Administrators (AUA). The subject of the lecture is equality and diversity in higher education (HE) leadership, or possibly the absence of equality and diversity. The author focuses on what can be done to ensure that capable women enter HE leadership…

  5. Diversity in the Workplace.

    Science.gov (United States)

    1996

    This document contains three papers presented at a symposium on diversity in the workplace moderated by Sandra Johnson at the 1996 conference of the Academy of Human Resource Development (AHRD). "Diversity and Development: An Assessment of Equal Opportunities and the Role of HRD in the Police Service" (Rashmi Biswas, Penny Dick) examines…

  6. Diversity at Work.

    Science.gov (United States)

    Sabo, Sandra R.

    2000-01-01

    Diversity in the workplace goes beyond racial, ethnic, and cultural backgrounds. It extends to those with disabilities of all types and older workers. Students must be able to acknowledge and appreciate peoples' differences and educators must integrate diversity into the classroom. (JOW)

  7. Global Diversity and Leadership.

    Science.gov (United States)

    Ruiz, Art

    2003-01-01

    Argues that global diversity has become a business imperative in today's business climate. Global diversity is of core importance even for companies that are considered domestic. Suggests community colleges need help in understanding their customer base and their shifting values in order to meet their needs and win customer loyalty. (NB)

  8. Species diversity modulates predation

    NARCIS (Netherlands)

    Kratina, P.; Vos, M.; Anholt, B.R.

    2007-01-01

    Predation occurs in a context defined by both prey and non-prey species. At present it is largely unknown how species diversity in general, and species that are not included in a predator's diet in particular, modify predator–prey interactions.Therefore we studied how both the density and diversity

  9. The marine diversity spectrum

    DEFF Research Database (Denmark)

    Reuman, Daniel C.; Gislason, Henrik; Barnes, Carolyn

    2014-01-01

    of taxonomy (all the species in a region regardless of clade) are much less studied but are equally important and will illuminate a different set of ecological and evolutionary processes. We develop and test a mechanistic model of how diversity varies with body mass in marine ecosystems. The model predicts...... the form of the diversity spectrum', which quantifies the distribution of species' asymptotic body masses, is a species analogue of the classic size spectrum of individuals, and which we have found to be a new and widely applicable description of diversity patterns. The marine diversity spectrum...... is predicted to be approximately linear across an asymptotic mass range spanning seven orders of magnitude. Slope -0 center dot 5 is predicted for the global marine diversity spectrum for all combined pelagic zones of continental shelf seas, and slopes for large regions are predicted to lie between -0 center...

  10. Putting Diversity to Work

    DEFF Research Database (Denmark)

    Holck, Lotte

    2016-01-01

    Purpose: The purpose of this article is to critically explore why a diversity agenda in favor of equal opportunities failed despite apparent organizational support and commitment to diversity. Design/methodology/approach: Drawing on data from a municipal center, this study inquires into how...... organizational dynamics of power and hierarchy influence change efforts to alter practices of inequality. The study is positioned within critical diversity research and structured around an analysis of the researcher’s fieldwork experiences. Findings: The analysis examines into why change efforts failed despite...... organizational approval of a diversity agenda, open-mindedness towards change and legitimacy in regard to diversity. Paradoxically, change efforts designed to alter the status quo were, in practice, derailed and circumvented through power dynamics reproducing organizational inequality. Research limitations...

  11. Managing Protean Diversity

    DEFF Research Database (Denmark)

    Marfelt, Mikkel Mouritz; Muhr, Sara Louise

    2016-01-01

    Recently, global workforce diversity and its management have received criticism for not paying attention to the contextual influence stemming from socially constructed dialectics of power and politics. These contextual dynamics, however, tend to be viewed as external to the organization....... In this article, we follow the call for critically investigating the contexts influencing diversity management by analyzing the development of a global human resource management project initiated to promote a culturally diverse workforce. We find that despite good intentions, as well as support from the top...... management, the project dissolves through micropolitics and power dynamics. We contribute to the critical literature on workforce diversity by identifying how organizational contextual dynamics influence the way the concept of workforce diversity is constructed and understood at work. Based on these findings...

  12. "Try to Understand Us":Aboriginal Elders’ Views on Exceptionality

    Directory of Open Access Journals (Sweden)

    Ron Phillips

    2010-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} This article provides an analysis of the views of four Elders at the “A Window to Seeing the World Differently, National Symposium on Aboriginal Special Education” that was held in October 2005 at First Nations University of Canada in Regina.  The symposium was an opportunity to provide educators, students, parents, and community members with information on Aboriginal views on special education.  Concern had been expressed over the high numbers of Aboriginal students being identified as “special needs” attending schools on reserves throughout Canada.  There was also concern over difficulties with the current special education system, e.g., funding, assessment, and service issues.  It was believed that the Aboriginal worldview of students with special needs as having special gifts from the Creator was not integrated into the curriculum or into teaching practices.  The article concludes with suggestions for educators on how to address exceptionalities in Aboriginal communities. Keywords: Aboriginal education, Elders, exceptionality, special education, Aboriginal special   education.

  13. Diverse crowds using diverse methods improves the scientific dialectic.

    Science.gov (United States)

    Motyl, Matt; Iyer, Ravi

    2015-01-01

    In science, diversity is vital to the development of new knowledge. We agree with Duarte et al. that we need more political diversity in social psychology, but contend that we need more religious diversity and methodological diversity as well. If some diversity is good, more is better (especially in science).

  14. Beyond the Diversity Crisis Model: Decentralized Diversity Planning and Implementation

    Science.gov (United States)

    Williams, Damon A.

    2008-01-01

    This article critiques the diversity crises model of diversity planning in higher education and presents a decentralized diversity planning model. The model is based on interviews with the nation's leading diversity officers, a review of the literature and the authors own experiences leading diversity change initiatives in higher education. The…

  15. Gambling and gambling policy in Norway--an exceptional case.

    Science.gov (United States)

    Rossow, Ingeborg; Bang Hansen, Marianne

    2016-04-01

    The aim of this paper is to provide an overview of the development and current status of gambling and gambling policy in Norway. An overview of the research literature and official documents and websites. Gambling on electronic gaming machines (EGMs) increased dramatically in the 1990s in response to technological development and liberalization of gambling policy. Restrictions on availability of EGM gambling occurred from 2006 to 2009 and included a ban on note acceptors, a temporary ban on EGMs and re-introduction of fewer and less aggressive machines under a state monopoly. The restrictions led to significant decreases in total gambling turnover, and several studies suggest that they led to fewer gambling and gambling problems. Various factors may explain why the restrictions were politically feasible. These include media coverage of gambling concerns and economic compensation for revenue losses under the monopoly. In an international context of deregulation of gambling markets, the Norwegian policy restrictions on gambling availability have represented an exceptional case and provide a rare opportunity to explore the outcomes of such regulations. Overall, studies suggest that the policy restrictions have led to reductions in gambling expenditures and problem gambling. © 2015 Society for the Study of Addiction.

  16. Security risks in nuclear waste management: Exceptionalism, opaqueness and vulnerability.

    Science.gov (United States)

    Vander Beken, Tom; Dorn, Nicholas; Van Daele, Stijn

    2010-01-01

    This paper analyses some potential security risks, concerning terrorism or more mundane forms of crime, such as fraud, in management of nuclear waste using a PEST scan (of political, economic, social and technical issues) and some insights of criminologists on crime prevention. Nuclear waste arises as spent fuel from ongoing energy generation or other nuclear operations, operational contamination or emissions, and decommissioning of obsolescent facilities. In international and EU political contexts, nuclear waste management is a sensitive issue, regulated specifically as part of the nuclear industry as well as in terms of hazardous waste policies. The industry involves state, commercial and mixed public-private bodies. The social and cultural dimensions--risk, uncertainty, and future generations--resonate more deeply here than in any other aspect of waste management. The paper argues that certain tendencies in regulation of the industry, claimed to be justified on security grounds, are decreasing transparency and veracity of reporting, opening up invisible spaces for management frauds, and in doing allowing a culture of impunity in which more serious criminal or terrorist risks could arise. What is needed is analysis of this 'exceptional' industry in terms of the normal cannons of risk assessment - a task that this paper begins. Copyright 2009 Elsevier Ltd. All rights reserved.

  17. Exceptionally High Electric Double Layer Capacitances of Oligomeric Ionic Liquids.

    Science.gov (United States)

    Matsumoto, Michio; Shimizu, Sunao; Sotoike, Rina; Watanabe, Masayoshi; Iwasa, Yoshihiro; Itoh, Yoshimitsu; Aida, Takuzo

    2017-11-15

    Electric double layer (EDL) capacitors are promising as next-generation energy accumulators if their capacitances and operation voltages are both high. However, only few electrolytes can simultaneously fulfill these two requisites. Here we report that an oligomeric ionic liquid such as IL4 TFSI with four imidazolium ion units in its structure provides a wide electrochemical window of ∼5.0 V, similar to monomeric ionic liquids. Furthermore, electrochemical impedance measurements using Au working electrodes demonstrated that IL4 TFSI exhibits an exceptionally high EDL capacitance of ∼66 μF/cm 2 , which is ∼6 times as high as those of monomeric ionic liquids so far reported. We also found that an EDL-based field effect transistor (FET) using IL4 TFSI as a gate dielectric material and SrTiO 3 as a channel material displays a very sharp transfer curve with an enhanced carrier accumulation capability of ∼64 μF/cm 2 , as determined by Hall-effect measurements.

  18. Hektor - an exceptional D-type family among Jovian Trojans

    Science.gov (United States)

    Rozehnal, J.; Brož, M.; Nesvorný, D.; Durda, D. D.; Walsh, K.; Richardson, D. C.; Asphaug, E.

    2016-11-01

    In this work, we analyse Jovian Trojans in the space of suitable resonant elements and we identify clusters of possible collisional origin by two independent methods: the hierarchical clustering and a so-called randombox. Compared to our previous work, we study a twice larger sample. Apart from Eurybates, Ennomos and 1996 RJ families, we have found three more clusters - namely families around asteroids (20961) Arkesilaos, (624) Hektor in the L4 libration zone and (247341) 2001 UV209 in L5. The families fulfill our stringent criteria, I.e. a high statistical significance, an albedo homogeneity and a steeper size-frequency distribution than that of background. In order to understand their nature, we simulate their long term collisional evolution with the Boulder code and dynamical evolution using a modified SWIFT integrator. Within the framework of our evolutionary model, we were able to constrain the age of the Hektor family to be either 1-4 Gyr or, less likely, 0.1-2.5 Gyr, depending on initial impact geometry. Since (624) Hektor itself seems to be a bilobed-shape body with a satellite, I.e. an exceptional object, we address its association with the D-type family and we demonstrate that the moon and family could be created during a single impact event. We simulated the cratering event using a smoothed particle hydrodynamics. This is also the first case of a family associated with a D-type parent body.

  19. Exceptional know how? Possible pitfalls of routinising genetic services.

    Science.gov (United States)

    Schmitz, Dagmar

    2010-09-01

    Genetic testing practices are increasingly advancing clinical medicine. This process of 'routinisation of genetics' has been conceived as a medical and ethical problem mainly because of the assumption that non-geneticists might lack the necessary skills to provide these services. In particular, the relevant theoretical knowledge in clinical genetics is viewed as insufficient in general practitioners and physicians from other specialities. Empirical findings seem to indicate significant variations not only in theoretical but also in practical knowledge between geneticists and non-geneticists. Several fields of practical knowledge-regarding for example the focus of clinical action, the relevance of therapeutic action or the normative framework-can be identified that are or could be areas of conflict when the routinisation of genetic services proceeds. From an ethical point of view, these variations in know how and background are especially relevant whenever the respective genetic service is concerned with medical information of exceptional normative quality, such as, for example, in prenatal genetic screening and diagnosis of untreatable conditions. Here, the clinically acquired practical knowledge of the non-geneticist could be particularly misleading insofar as there is no relation to therapy and-in a narrow sense-no clinical utility to be assessed. Non-geneticists need a chance to acquire the relevant theoretical and practical knowledge in order to understand and fulfil their own duties in the respective situations in a way that secures the important rights at stake of their patients and clients.

  20. Petro-Canada 2002 annual report : profitability and exceptional growth

    International Nuclear Information System (INIS)

    2003-01-01

    Financial information from Petro-Canada was presented and a review of their 2002 operations was made available for the benefit of shareholders. Petro-Canada is focused on 5 core businesses: Terra Nova east coast oil, oil sands development at MacKay River, North American natural gas exploration in the foothills, operations in North Africa, and the petroleum downstream sector. Highlights of 2002 for each of these core business areas were presented. In general, the report states that 2002 was an exceptional year with an operating performance that combined with favourable commodity prices to produce excellent financial results. The most significant event in 2002 was the acquisition and integration of the upstream businesses of Veba Oil and Gas, creating a new core international business for Petro-Canada. This report summarized the company's energy resource activities and presented an operations review as well as consolidated financial statements, and common share information including the accounts of Petro-Canada and its subsidiaries and the company's proportionate share of assets, liabilities, revenues, expenses and cash flows of joint ventures. Revenue and expenditure statements were summarized by source. tabs., figs

  1. Allometry indicates giant eyes of giant squid are not exceptional.

    Science.gov (United States)

    Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Gamarra, Ashlee R; Lee, Johanna J; Wainwright, Peter C

    2013-02-18

    The eyes of giant and colossal squid are among the largest eyes in the history of life. It was recently proposed that sperm whale predation is the main driver of eye size evolution in giant squid, on the basis of an optical model that suggested optimal performance in detecting large luminous visual targets such as whales in the deep sea. However, it is poorly understood how the eye size of giant and colossal squid compares to that of other aquatic organisms when scaling effects are considered. We performed a large-scale comparative study that included 87 squid species and 237 species of acanthomorph fish. While squid have larger eyes than most acanthomorphs, a comparison of relative eye size among squid suggests that giant and colossal squid do not have unusually large eyes. After revising constants used in a previous model we found that large eyes perform equally well in detecting point targets and large luminous targets in the deep sea. The eyes of giant and colossal squid do not appear exceptionally large when allometric effects are considered. It is probable that the giant eyes of giant squid result from a phylogenetically conserved developmental pattern manifested in very large animals. Whatever the cause of large eyes, they appear to have several advantages for vision in the reduced light of the deep mesopelagic zone.

  2. Arthropod diversity in a tropical forest

    DEFF Research Database (Denmark)

    Basset, Yves; Cizek, Lukas; Cuénoud, Philippe

    2012-01-01

    breadth of arthropod taxa from the soil to the forest canopy in the San Lorenzo forest, Panama. We collected 6144 arthropod species from 0.48 hectare and extrapolated total species richness to larger areas on the basis of competing models. The whole 6000-hectare forest reserve most likely sustains 25......,000 arthropod species. Notably, just 1 hectare of rainforest yields >60% of the arthropod biodiversity held in the wider landscape. Models based on plant diversity fitted the accumulated species richness of both herbivore and nonherbivore taxa exceptionally well. This lends credence to global estimates...

  3. A 4-year non-randomized comparative phase-IV study of early rheumatoid arthritis: integrative anthroposophic medicine for patients with preference against DMARDs versus conventional therapy including DMARDs for patients without preference

    Directory of Open Access Journals (Sweden)

    Hamre HJ

    2018-03-01

    Full Text Available Harald J Hamre,1 Van N Pham,2 Christian Kern,3 Rolf Rau,4 Jörn Klasen,3 Ute Schendel,5 Lars Gerlach,6 Attyla Drabik,2 Ludger Simon6,† 1Institute for Applied Epistemology and Medical Methodology at the Witten/Herdecke University, Freiburg, Germany; 2Institute of Statistics in Medicine, Universitätsklinikum Düsseldorf, Düsseldorf, Germany; 3Department of Integrative Medicine, Asklepios Westklinikum, Hamburg, Germany; 4Department of Rheumatology, Evangelisches Fachkrankenhaus Ratingen, Ratingen, Germany; 5Department of Rheumatology, m&i-Fachklinik Bad Pyrmont, Bad Pyrmont, Germany; 6Department of Internal Medicine and Gastroenterology, Filderklinik, Filderstadt, Germany †Dr Ludger Simon passed away on June 10, 2016 Background: While disease-modifying antirheumatic drugs (DMARDs are a mainstay of therapy for rheumatoid arthritis (RA, some patients with early RA refuse DMARDs. In anthroposophic medicine (AM, a treatment strategy for early RA without DMARDs has been developed. Preliminary data suggest that RA symptoms and inflammatory markers can be reduced under AM, without DMARDs. Patients and methods: Two hundred and fifty-one self-selected patients aged 16–70 years, starting treatment for RA of <3 years duration, without prior DMARD therapy, participated in a prospective, non-randomized, comparative Phase IV study. C-patients were treated in clinics offering conventional therapy including DMARDs, while A-patients had chosen treatment in anthroposophic clinics, without DMARDs. Both groups received corticosteroids and nonsteroidal anti-inflammatory drugs (NSAIDs. Primary outcomes were intensity of RA symptoms measured by self-rating on visual analog scales, C-reactive protein, radiological progression, study withdrawals, serious adverse events (SAE, and adverse drug reactions in months 0–48. Results: The groups were similar in most baseline characteristics, while A-patients had longer disease duration (mean 15.1 vs 10.8 months, p<0

  4. How diversity gets lost

    DEFF Research Database (Denmark)

    Oudshoorn, Nelly; Neven, Louis; Stienstra, M.

    2016-01-01

    This article adopts an intersectional approach to investigate how age, gender, and diversity are represented, silenced, or prioritized in design. Based on a comparative study of design practices of information and communication technologies (ICTs) for young girls and older people, this article...... describes differences and similarities in the ways in which designers tried to cope with diversity. Ultimately diversity was neglected, and the developers relied on hegemonic views of gender and age, constructed older people and young girls as an “other,” and consequently their input was neglected...

  5. Arthropod diversity in a tropical forest.

    Science.gov (United States)

    Basset, Yves; Cizek, Lukas; Cuénoud, Philippe; Didham, Raphael K; Guilhaumon, François; Missa, Olivier; Novotny, Vojtech; Ødegaard, Frode; Roslin, Tomas; Schmidl, Jürgen; Tishechkin, Alexey K; Winchester, Neville N; Roubik, David W; Aberlenc, Henri-Pierre; Bail, Johannes; Barrios, Héctor; Bridle, Jon R; Castaño-Meneses, Gabriela; Corbara, Bruno; Curletti, Gianfranco; Duarte da Rocha, Wesley; De Bakker, Domir; Delabie, Jacques H C; Dejean, Alain; Fagan, Laura L; Floren, Andreas; Kitching, Roger L; Medianero, Enrique; Miller, Scott E; Gama de Oliveira, Evandro; Orivel, Jérôme; Pollet, Marc; Rapp, Mathieu; Ribeiro, Sérvio P; Roisin, Yves; Schmidt, Jesper B; Sørensen, Line; Leponce, Maurice

    2012-12-14

    Most eukaryotic organisms are arthropods. Yet, their diversity in rich terrestrial ecosystems is still unknown. Here we produce tangible estimates of the total species richness of arthropods in a tropical rainforest. Using a comprehensive range of structured protocols, we sampled the phylogenetic breadth of arthropod taxa from the soil to the forest canopy in the San Lorenzo forest, Panama. We collected 6144 arthropod species from 0.48 hectare and extrapolated total species richness to larger areas on the basis of competing models. The whole 6000-hectare forest reserve most likely sustains 25,000 arthropod species. Notably, just 1 hectare of rainforest yields >60% of the arthropod biodiversity held in the wider landscape. Models based on plant diversity fitted the accumulated species richness of both herbivore and nonherbivore taxa exceptionally well. This lends credence to global estimates of arthropod biodiversity developed from plant models.

  6. Mindfulness Training for Health Profession Students-The Effect of Mindfulness Training on Psychological Well-Being, Learning and Clinical Performance of Health Professional Students: A Systematic Review of Randomized and Non-randomized Controlled Trials.

    Science.gov (United States)

    McConville, Janet; McAleer, Rachael; Hahne, Andrew

    High levels of stress have been identified in medical students and increasingly in other health profession student population groups. As stress can affect psychological well-being and interfere with learning and clinical performance, there is a clear argument for universities to include health professional student well-being as an outcome in core curriculum. Mindfulness training is a potential construct to manage stress and enhance academic success. The aims of this systematic review were to assess the effectiveness of mindfulness training in medical and other health professional student population groups and to compare the effectiveness of the different mindfulness-based programs. A literature search was completed using The Cochrane library, Medline, Cinahl, Embase, Psychinfo, and ERIC (proquest) electronic databases from inception to June 2016. Randomized and non-randomized controlled trials were included. Of the potential 5355 articles, 19 met the inclusion criteria. Studies focused on medical (n = 10), nursing (n = 4), social work (n = 1), psychology (n = 1), and medical plus other health (n = 3) students. Interventions were based on mindfulness. The 19 studies included 1815 participants. Meta-analysis was performed evaluating the effect of mindfulness training on mindfulness, anxiety, depression, stress, mood, self-efficacy, and empathy. The effect of mindfulness on academic performance was discussed. Mindfulness-based interventions decrease stress, anxiety, and depression and improve mindfulness, mood, self-efficacy, and empathy in health profession students. Due to the range of presentation options, mindfulness training can be relatively easily adapted and integrated into health professional training programs. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Impact of a Multifaceted and Clinically Integrated Training Program in Evidence-Based Practice on Knowledge, Skills, Beliefs and Behaviour among Clinical Instructors in Physiotherapy: A Non-Randomized Controlled Study.

    Directory of Open Access Journals (Sweden)

    Nina Rydland Olsen

    Full Text Available Physiotherapists practicing at clinical placement sites assigned the role as clinical instructors (CIs, are responsible for supervising physiotherapy students. For CIs to role model evidence-based practice (EBP they need EBP competence. The aim of this study was to assess the short and long term impact of a six-month multifaceted and clinically integrated training program in EBP on the knowledge, skills, beliefs and behaviour of CIs supervising physiotherapy students.We invited 37 CIs to participate in this non-randomized controlled study. Three self-administered questionnaires were used pre- and post-intervention, and at six-month follow-up: 1 The Adapted Fresno test (AFT, 2 the EBP Belief Scale and 3 the EBP Implementation Scale. The analysis approach was linear regression modeling using Generalized Estimating Equations.In total, 29 CIs agreed to participate in the study: 14 were invited to participate in the intervention group and 15 were invited to participate in the control group. One in the intervention group and five in the control group were lost to follow-up. At follow-up, the group difference was statistically significant for the AFT (mean difference = 37, 95% CI (15.9 -58.1, p < 0.001 and the EBP Beliefs scale (mean difference = 8.1, 95% CI (3.1 -13.2, p = 0.002, but not for the EBP Implementation scale (mean difference = 1.8. 95% CI (-4.5-8.1, p = 0.574. Comparing measurements over time, we found a statistically significant increase in mean scores related to all outcome measures for the intervention group only.A multifaceted and clinically integrated training program in EBP was successful in improving EBP knowledge, skills and beliefs among CIs. Future studies need to ensure long-term EBP behaviour change, in addition to assessing CIs' abilities to apply EBP knowledge and skills when supervising students.

  8. Immunogenicity and safety of an adjuvanted herpes zoster subunit candidate vaccine in adults ≥ 50 years of age with a prior history of herpes zoster: A phase III, non-randomized, open-label clinical trial.

    Science.gov (United States)

    Godeaux, Olivier; Kovac, Martina; Shu, Daniel; Grupping, Katrijn; Campora, Laura; Douha, Martine; Heineman, Thomas C; Lal, Himal

    2017-05-04

    This phase III, non-randomized, open-label, multi-center study (NCT01827839) evaluated the immunogenicity and safety of an adjuvanted recombinant subunit herpes zoster (HZ) vaccine (HZ/su) in adults aged ≥ 50 y with prior physician-documented history of HZ. Participants (stratified by age: 50-59, 60-69 and ≥ 70 y) received 2 doses of HZ/su 2 months apart and were followed-up for another 12 months. Anti-glycoprotein E (gE) antibodies were measured by enzyme-linked immunosorbent assay before vaccination and 1 month after the second dose (Month 3). Solicited local and general adverse events (AEs) were recorded for 7 d and unsolicited AEs for 30 d after each vaccination. Serious AEs were recorded until study end. The primary immunogenicity objective was met if the lower limit of the 95% confidence interval (CI) of the vaccine response rate (VRR), defined as a 4-fold increase in anti-gE over baseline, at Month 3 was ≥ 60%. 96 participants (32/age group) were enrolled. The primary immunogenicity objective was met, as the VRR at Month 3 was 90.2% (95% CI: 81.7-95.7). Geometric mean anti-gE antibody concentrations at Month 3 were similar across age groups. 77.9% and 71.6% of participants reported local and general solicited AEs, respectively. The most frequent solicited AEs were pain at injection site, fatigue, headache, myalgia and shivering. The HZ/su vaccine was immunogenic in adults aged ≥ 50 y with a physician-documented history of HZ, and no safety concerns were identified.

  9. A non-randomized study in consecutive patients with postcholecystectomy refractory biliary leaks who were managed endoscopically with the use of multiple plastic stents or fully covered self-expandable metal stents (with videos).

    Science.gov (United States)

    Canena, Jorge; Liberato, Manuel; Meireles, Liliane; Marques, Inês; Romão, Carlos; Coutinho, António Pereira; Neves, Beatriz Costa; Veiga, Pedro Mota

    2015-07-01

    Endoscopic management of postcholecystectomy biliary leaks is widely accepted as the treatment of choice. However, refractory biliary leaks after a combination of biliary sphincterotomy and the placement of a large-bore (10F) plastic stent can occur, and the optimal rescue endotherapy for this situation is unclear. To compare the clinical effectiveness of the use of a fully covered self-expandable metal stent (FCSEMS) with the placement of multiple plastic stents (MPS) for the treatment of postcholecystectomy refractory biliary leaks. Prospective study. Two tertiary-care referral academic centers and one general district hospital. Forty consecutive patients with refractory biliary leaks who underwent endoscopic management. Temporary placement of MPS (n = 20) or FCSEMSs (n = 20). Clinical outcomes of endotherapy as well as the technical success, adverse events, need for reinterventions, and prognostic factors for clinical success. Endotherapy was possible in all patients. After endotherapy, closure of the leak was accomplished in 13 patients (65%) who received MPS and in 20 patients (100%) who received FCSEMSs (P = .004). The Kaplan-Meier (log-rank) leak-free survival analysis showed a statistically significant difference between the 2 patient populations (χ(2) [1] = 8.30; P stents (P = .024), a plastic stent diameter <20F (P = .006), and a high-grade biliary leak (P = .015) were shown to be significant predictors of treatment failure with MPS. The 7 patients in whom placement of MPS failed were retreated with FCSEMSs, resulting in closure of the leaks in all cases. Non-randomized design. In our series, the results of the temporary placement of FCSEMSs for postcholecystectomy refractory biliary leaks were superior to those from the use of MPS. A randomized study is needed to confirm our results before further recommendations. Copyright © 2015 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

  10. CERN Diversity Newsletter - July 2015

    CERN Document Server

    Kaltenhauser, Kristin; CERN. Geneva. HR Department

    2015-01-01

    The first official edition of the CERN Diversity Newsletter, informing on recent and ongoing diversity activities, and interesting reads, videos and other links related to diversity. Subscribe here: https://diversity.web.cern.ch/2015/07/subscribe-diversity-newsletter

  11. Exceptional deliveries: home births as ethical anomalies in American obstetrics.

    Science.gov (United States)

    Wendland, Claire L

    2013-01-01

    Interest in home birth appears to be growing among American women, and most obstetricians can expect to encounter patients who are considering home birth. In 2011, the American College of Obstetricians and Gynecologists (ACOG) issued an opinion statement intended to guide obstetricians in responding to such patients. In this article, I examine the ACOG statement in light of the historical and contemporary clinical realities surrounding home birth in the United States, an examination guided in part by my own experiences as an obstetrician in home-birth-friendly and home-birth-unfriendly medical milieus. Comparison with other guidelines indicates that ACOG treats home birth as an ethical exception: comparable evidence leads to strikingly different recommendations in the case of home birth and the case of trial of labor following a prior cesarean; and ACOG treats other controversial issues that involve similar ethical questions quite differently. By casting the provision of information as not just the primary but the sole ethical responsibility of the obstetrician, ACOG statement obviates obstetricians' responsibilities to provide appropriate clinical care and to make the safest possible clinical environment for those mothers who choose home birth and for their newborns. What, on its face, seems to be a statement of respect for women's autonomy, implicitly authorizes behaviors that unethically restrain truly autonomous choices. Obstetricians need not attend home births, I argue. Our ethical duties do, however, oblige us (1) to refer clients to skilled clinicians who will attend home birth, (2) to continue respectful antenatal care for those women choosing home birth, (3) to provide appropriate consultation to home birth attendants, and (4) to ensure that transfers of care are smooth and nonpunitive.

  12. Surface chemical modification for exceptional wear life of MEMS materials

    Directory of Open Access Journals (Sweden)

    R. Arvind Singh

    2011-12-01

    Full Text Available Micro-Electro-Mechanical-Systems (MEMS are built at micro/nano-scales. At these scales, the interfacial forces are extremely strong. These forces adversely affect the smooth operation and cause wear resulting in the drastic reduction in wear life (useful operating lifetime of actuator-based devices. In this paper, we present a surface chemical modification method that reduces friction and significantly extends the wear life of the two most popular MEMS structural materials namely, silicon and SU-8 polymer. The method includes surface chemical treatment using ethanolamine-sodium phosphate buffer, followed by coating of perfluoropolyether (PFPE nanolubricant on (i silicon coated with SU-8 thin films (500 nm and (ii MEMS process treated SU-8 thick films (50 μm. After the surface chemical modification, it was observed that the steady-state coefficient of friction of the materials reduced by 4 to 5 times and simultaneously their wear durability increased by more than three orders of magnitude (> 1000 times. The significant reduction in the friction coefficients is due to the lubrication effect of PFPE nanolubricant, while the exceptional increase in their wear life is attributed to the bonding between the -OH functional group of ethanolamine treated SU-8 thin/thick films and the -OH functional group of PFPE. The surface chemical modification method acts as a common route to enhance the performance of both silicon and SU-8 polymer. It is time-effective (process time ≤ 11 min, cost-effective and can be readily integrated into MEMS fabrication/assembly processes. It can also work for any kind of structural material from which the miniaturized devices are/can be made.

  13. Scintigraphic and radiologic aspects of two exceptional tumors at knee

    International Nuclear Information System (INIS)

    Lescout, J.M.; Bussy, E.; Tourrette, J.H.; Dussau, J.P.; Gadea, J.; Camelli, M.

    1997-01-01

    We present two cases of rare vascular tumors of knee which in the frame of the pre-surgery extension examination were successfully explored by the Osseous Scintigraphy (OS) and Magnetic Resonance Imagery (MRI). The first case was a young girl 17 years old accusing since two years a mechanical pain in the left knee, without radiographic or biologic anomalies. Early profile incidence of OS indicates an articular hyperemia of geometrical shape which later disappeared totally, what evoked the absence of osteoblastic activity of a hyper-vascularized lesion. The MRI showed the existence of an extraosseous tumor in the retro-patellar loge. The histologic analysis led to the diagnosis of synovial hemangioma, a rare benign tumor which benefited by a complete extirpation followed by rapid remission of walking. The second case was a male 53 years old which presented a painful right sub-patellar tumefaction with a major osteolysis of 1/3 upper tibia, by standard radiography. The OS in two phases indicated a unique hyper-vascularized very active osseous affliction. The MRI has confirmed the well circumscribed afflicted zone of the tibia's proximal metaphysis and showed an invasion of the soft parts. The pathologist concluded on a epithelial hemangioma-endothelioma, a vascular tumor of intermediate malignity which benefited by an extirpation with osseous graft showing no negative evolution after one year. In the vast frame of the skeletal tumors these exceptional vascular peri-articular afflictions allow illustrating the complementarity of OS and MRI which give to the surgery all the information useful for their extension on their more or less vascularized character and on their osteoblastic component

  14. Spatial scale and β-diversity of terrestrial vertebrates in Mexico

    OpenAIRE

    Ochoa-Ochoa, Leticia M.; Munguía, Mariana; Lira-Noriega, Andrés; Sánchez-Cordero, Víctor; Flores-Villela, Oscar; Navarro-Sigüenza, Adolfo; Rodríguez, Pilar

    2014-01-01

    Patterns of diversity are scale dependent and beta-diversity is not the exception. Mexico is megadiverse due to its high beta diversity, but little is known if it is scale-dependent and/or taxonomic-dependent. We explored these questions based on the self-similarity hypothesis of beta-diversity across spatial scales. Using geographic distribution ranges of 2 513 species, we compared the beta-diversity patterns of 4 groups of terrestrial vertebrates, across 7 spatial scales (from ~10 km² to 16...

  15. Evaluating human genetic diversity

    National Research Council Canada - National Science Library

    This book assesses the scientific value and merit of research on human genetic differences--including a collection of DNA samples that represents the whole of human genetic diversity--and the ethical...

  16. Managing biological diversity

    Science.gov (United States)

    Samson, Fred B.; Knopf, Fritz L.

    1993-01-01

    Biological diversity is the variety of life and accompanying ecological processes (Off. Technol. Assess. 1987, Wilcove and Samson 1987, Keystone 1991). Conservation of biological diversity is a major environmental issue (Wilson 1988, Counc. Environ. Quality 1991). The health and future of the earth's ecological systems (Lubchenco et al. 1991), global climate change (Botkin 1990), and an ever-increasing rate in loss of species, communities, and ecological systems (Myers 1990) are among issues drawing biological diversity to the mainstream of conservation worldwide (Int. Union Conserv. Nat. and Nat. Resour. [IUCN] et al. 1991). The legal mandate for conserving biological diversity is now in place (Carlson 1988, Doremus 1991). More than 19 federal laws govern the use of biological resources in the United States (Rein 1991). The proposed National Biological Diversity Conservation and Environmental Research Act (H.R. 585 and S.58) notes the need for a national biological diversity policy, would create a national center for biological diversity research, and recommends a federal interagency strategy for ecosystem conservation. There are, however, hard choices ahead for the conservation of biological diversity, and biologists are grappling with how to set priorities in research and management (Roberts 1988). We sense disillusion among field biologists and managers relative to how to operationally approach the seemingly overwhelming charge of conserving biological diversity. Biologists also need to respond to critics like Hunt (1991) who suggest a tree farm has more biological diversity than an equal area of old-growth forest. At present, science has played only a minor role in the conservation of biological diversity (Weston 1992) with no unified approach available to evaluate strategies and programs that address the quality and quantity of biological diversity (Murphy 1990, Erwin 1992). Although actions to conserve biological diversity need to be clearly defined by

  17. Evaluating human genetic diversity

    National Research Council Canada - National Science Library

    ... into human evolution and origins and serving as a springboard for important medical research. It also addresses issues of confidentiality and individual privacy for participants in genetic diversity research studies.

  18. Life: Complexity and Diversity

    Indian Academy of Sciences (India)

    tinual increase in the diversity of life over evolutionary time. Ways of ... Centre for Ecological. Scienc'es .... plants evolved flowers to attract pollinators and reward them with .... with the evolving complexity of their interactions in communi- ties.

  19. Convergent evolution in aquatic tetrapods: insights from an exceptional fossil mosasaur.

    Directory of Open Access Journals (Sweden)

    Johan Lindgren

    Full Text Available Mosasaurs (family Mosasauridae are a diverse group of secondarily aquatic lizards that radiated into marine environments during the Late Cretaceous (98-65 million years ago. For the most part, they have been considered to be simple anguilliform swimmers--i.e., their propulsive force was generated by means of lateral undulations incorporating the greater part of the body--with unremarkable, dorsoventrally narrow tails and long, lizard-like bodies. Convergence with the specialized fusiform body shape and inferred carangiform locomotory style (in which only a portion of the posterior body participates in the thrust-producing flexure of ichthyosaurs and metriorhynchid crocodyliform reptiles, along with cetaceans, has so far only been recognized in Plotosaurus, the most highly derived member of the Mosasauridae. Here we report on an exceptionally complete specimen (LACM 128319 of the moderately derived genus Platecarpus that preserves soft tissues and anatomical details (e.g., large portions of integument, a partial body outline, putative skin color markings, a downturned tail, branching bronchial tubes, and probable visceral traces to an extent that has never been seen previously in any mosasaur. Our study demonstrates that a streamlined body plan and crescent-shaped caudal fin were already well established in Platecarpus, a taxon that preceded Plotosaurus by 20 million years. These new data expand our understanding of convergent evolution among marine reptiles, and provide insights into their evolution's tempo and mode.

  20. An exceptional role for flowering plant physiology in the expansion of tropical rainforests and biodiversity.

    Science.gov (United States)

    Boyce, C Kevin; Lee, Jung-Eun

    2010-11-22

    Movement of water from soil to atmosphere by plant transpiration can feed precipitation, but is limited by the hydraulic capacities of plants, which have not been uniform through time. The flowering plants that dominate modern vegetation possess transpiration capacities that are dramatically higher than any other plants, living or extinct. Transpiration operates at the level of the leaf, however, and how the impact of this physiological revolution scales up to the landscape and larger environment remains unclear. Here, climate modelling demonstrates that angiosperms help ensure aseasonally high levels of precipitation in the modern tropics. Most strikingly, replacement of angiosperm with non-angiosperm vegetation would result in a hotter, drier and more seasonal Amazon basin, decreasing the overall area of ever-wet rainforest by 80 per cent. Thus, flowering plant ecological dominance has strongly altered climate and the global hydrological cycle. Because tropical biodiversity is closely tied to precipitation and rainforest area, angiosperm climate modification may have promoted diversification of the angiosperms themselves, as well as radiations of diverse vertebrate and invertebrate animal lineages and of epiphytic plants. Their exceptional potential for environmental modification may have contributed to divergent responses to similar climates and global perturbations, like mass extinctions, before and after angiosperm evolution.

  1. Consequences of black exceptionalism? Interracial unions with blacks, depressive symptoms, and relationship satisfaction.

    Science.gov (United States)

    Kroeger, Rhiannon A; Williams, Kristi

    2011-01-01

    Using data from Wave 4 (2008) of the National Longitudinal Study of Adolescent Health (N = 7,466), we examine potential consequences of black exceptionalism in the context of interracial relationships among nonblack respondents. While increasing racial diversity and climbing rates of interracial unions have fostered the notion that racial boundaries within the United States are fading, our results add to the accumulating evidence that racial/ethnic boundaries persist in U.S. society. Results suggest that among non-Black respondents there is more stigma and disapproval attached to relationships with Blacks than there are to relationships with members of other racial/ethnic groups. Specifically, our results indicate that nonblack individuals with black partners have significantly more depressive symptoms and less relationship satisfaction than their counterparts with nonblack partners, regardless of respondent race and whether the nonblack partner is the same versus a different race from the respondent. Further, the relationship between partner race and depressive symptoms is partially and significantly mediated by relationship satisfaction.

  2. Leadership in diversity.

    Science.gov (United States)

    Hunt, P L

    1994-12-01

    As principal change agents, healthcare leaders are well positioned to integrate diversity into their institutions' organizational structure. Thus healthcare leaders must be competent in handling diversity issues. Diversity refers to any characteristic that helps shape a person's attitudes, behaviors, perspective, and interpretation of what is "normal." In the healthcare ministry, diversity encompasses the cultural differences that can be found across functions or among organizations when they merge or partner. Managers and supervisors will have to be familiar with the nuances of diversity if they are to be effective. Those managers who are not adept at incorporating diversity into human resource management may incorrectly evaluate subordinates' capabilities and provide inappropriate training or supervision. As a result, some employees may be underutilized. Others may resist needed direction, overlook instructions, or hide problems such as a language barrier. If executives, marketers, and strategic planners are to develop relevant healthcare services that take into account the needs of their constituencies, they will need to determine how different groups understand and access healthcare. Healthcare leaders who know how to uncover cultural dynamics and challenge cultural assumptions will go far in enabling their staff and managers to confront personal attitudes about community residents. Ultimately, quality of service delivery will be improved.

  3. Diversity of T cell epitopes in Plasmodium falciparum circumsporozoite protein likely due to protein-protein interactions.

    Directory of Open Access Journals (Sweden)

    Nagesh R Aragam

    Full Text Available Circumsporozoite protein (CS is a leading vaccine antigen for falciparum malaria, but is highly polymorphic in natural parasite populations. The factors driving this diversity are unclear, but non-random assortment of the T cell epitopes TH2 and TH3 has been observed in a Kenyan parasite population. The recent publication of the crystal structure of the variable C terminal region of the protein allows the assessment of the impact of diversity on protein structure and T cell epitope assortment. Using data from the Gambia (55 isolates and Malawi (235 isolates, we evaluated the patterns of diversity within and between epitopes in these two distantly-separated populations. Only non-synonymous mutations were observed with the vast majority in both populations at similar frequencies suggesting strong selection on this region. A non-random pattern of T cell epitope assortment was seen in Malawi and in the Gambia, but structural analysis indicates no intramolecular spatial interactions. Using the information from these parasite populations, structural analysis reveals that polymorphic amino acids within TH2 and TH3 colocalize to one side of the protein, surround, but do not involve, the hydrophobic pocket in CS, and predominately involve charge switches. In addition, free energy analysis suggests residues forming and behind the novel pocket within CS are tightly constrained and well conserved in all alleles. In addition, free energy analysis shows polymorphic residues tend to be populated by energetically unfavorable amino acids. In combination, these findings suggest the diversity of T cell epitopes in CS may be primarily an evolutionary response to intermolecular interactions at the surface of the protein potentially counteracting antibody-mediated immune recognition or evolving host receptor diversity.

  4. Does Labor Diversity Promote Entrepreneurship?

    DEFF Research Database (Denmark)

    Marino, Marianna; Parrotta, Pierpaolo; Pozzoli, Dario

    We find evidence that workforce educational diversity promotes entrepreneurial behavior of employees as well as the formation of new firms, whereas diversity in demographics hinders transitions to selfemployment. Ethnic diversity favors entrepreneurship in financial and business services....

  5. Is surgical workforce diversity increasing?

    Science.gov (United States)

    Andriole, Dorothy A; Jeffe, Donna B; Schechtman, Kenneth B

    2007-03-01

    We sought to determine the extent to which recent increases in levels of gender and racial diversity in the overall resident-physician workforce were evident among core-surgical specialty resident workforces. Chi-square tests for trend assessed the importance of changes from 1996 to 2004 in proportions of women and African Americans in the surgery-resident workforce. Surgery-resident trends were compared with overall resident workforce trends using two-tailed t-tests to compare regression slopes that quantified rates of change over time. Chi-square tests assessed differences between proportions of women and African Americans in the current overall board-certified workforce and their proportions in the surgery board-certified workforce. From 1996 to 2004, proportions of women increased in all seven surgical specialties studied. Compared with the overall trend toward increasing proportions of women in the resident workforce, the trend in one surgical specialty was larger (obstetrics/gynecology, p 0.05), and two were smaller (each p 0.05). Proportions of African Americans decreased in three specialties (each p workforce, except obstetrics/gynecology, remained lower than in the overall board-certified workforce (each p workforces have persisted since 1996 and will likely perpetuate ongoing surgery board-certified workforce disparities.

  6. Divergence Measures as Diversity Indices

    OpenAIRE

    Abou-Moustafa, Karim T.

    2014-01-01

    Entropy measures of probability distributions are widely used measures in ecology, biology, genetics, and in other fields, to quantify species diversity of a community. Unfortunately, entropy-based diversity indices, or diversity indices for short, suffer from three problems. First, when computing the diversity for samples withdrawn from communities with different structures, diversity indices can easily yield non-comparable and hard to interpret results. Second, diversity indices impose weig...

  7. 42 CFR 137.22 - May the Secretary consider uncorrected significant and material audit exceptions identified...

    Science.gov (United States)

    2010-10-01

    ... and material audit exceptions identified regarding centralized financial and administrative functions... Tribes for Participation in Self-Governance Planning Phase § 137.22 May the Secretary consider uncorrected significant and material audit exceptions identified regarding centralized financial and...

  8. Human impacts on genetic diversity in forest ecosystems

    Energy Technology Data Exchange (ETDEWEB)

    Ledig, F T [Inst. of Forest Genetics, Southwest Forest and Range Experiment Station, USDA Forest Service, Berkeley (US)

    1992-01-01

    Humans have converted forest to agricultural and urban uses, exploited species, fragmented wildlands, changed the demographic structure of forests, altered habitat, degraded the environment with atmospheric and soil pollutants, introduced exotic pests and competitors, and domesticated favored species. None of these activities is new; perhaps with the exception of atmospheric pollution, they date back to prehistory. All have impacted genetic diversity by their influence on the evolutionary processes of extinction, selection, drift, gene flow, and mutation, sometimes increasing diversity, as int he case of domestication, but often reducing it. Even in the absence of changes in diversity, mating systems were altered, changing the genetic structure of populations. Demographic changes influenced selection by increasing the incidence of disease. Introduction of exotic diseases, insects, mammalian herbivores, and competing vegetation has had the best-documented effects on genetic diversity, reducing both species diversity and intraspecific diversity. Deforestation has operated on a vast scale to reduce diversity by direct elimination of locally-adapted populations. Atmospheric pollution and global warming will be a major threat in the near future, particularly because forests are fragmented and migration is impeded. Past impacts can be estimated with reference to expert knowledge, but hard data are often laching. Baselines are needed to quantify future impacts and provide an early warning of problems. Genetic inventories of indicator species can provide the baselines against which to measure changes in diversity. (author) (44 refs.).

  9. Teaching for Diversity: Addressing Diversity Issues in Responsive ESL Instruction

    Science.gov (United States)

    Fu, Jing

    2013-01-01

    Student diversity has become a typical phenomenon in American public schools. The impact of increasing diversity on literacy instruction is unchallenged. Teachers reinforce this message by often citing ESL student diversity as a barrier for literacy teaching. In order to better understand the complexity of diversity issues, I explored two ESL…

  10. NASFAA Diversity and Inclusion: Recommendations of the Professional Diversity Caucus

    Science.gov (United States)

    National Association of Student Financial Aid Administrators, 2015

    2015-01-01

    NASFAA's Diversity and Inclusion Report emphasizes the importance of diversity and inclusivity to NASFAA. Included in this report is a diversity statement developed by NASFAA's Professional Diversity Caucus, and approved by NASFAA's Board in March of 2015. The Caucus convened in the summer of 2014 to better understand issues related to diversity…

  11. Effectiveness of the “What’s Up!” Intervention to Reduce Stigma and Psychometric Properties of the Youth Program Questionnaire (YPQ: Results from a Cluster Non-randomized Controlled Trial Conducted in Catalan High Schools

    Directory of Open Access Journals (Sweden)

    Laura Andrés-Rodríguez

    2017-09-01

    Full Text Available Mental disorders are highly prevalent in the general population, and people who experience them are frequently stigmatized. Stigma has a very negative impact on social, academic/professional, and personal life. Considering the high rates of mental disorders among children and adolescents (13.4% and how critical this age is in the formation of nuclear beliefs, many campaigns to combat stigma have been developed in the last decade, with mixed results. The OBERTAMENT initiative has produced various anti-stigma campaigns in Catalonia (Spain. In the present study, the main objective was to report on the effectiveness of the OBERTAMENT “What’s up!” intervention, a curricular intervention including education and social contact conducted by the teachers in the classroom with teenagers aged between 14 and 18. Prior to this, we examined the psychometric properties of the Youth Program Questionnaire (YPQ, our main outcome measure, in terms of dimensionality, reliability, and validity. A cluster non-randomized controlled trial was conducted to assess this intervention, which was tested in nine high schools situated in the Barcelona region. A convenience sample of 261 students formed the intervention group and 132 the control group (52% women, mean age = 14, SD = 0.47. The assignment to study conditions was conducted by Departament d’Ensenyament (Department of Education, Generalitat de Catalunya (Catalan Government. Participants were evaluated at baseline, post-intervention, and 9-month follow-up. The main outcome measure of this study was the YPQ. The Reported and Intended Behavior Scale (RIBS was used as secondary outcome measure. The statistical analysis indicated that the YPQ possesses a two-factor structure (stereotypical attitudes and intended behavior and sound psychometric properties. The multilevel mixed-effects models revealed statistically significant interactions for both study measures and post hoc intragroup analyses revealed a

  12. Diversity of Poissonian populations.

    Science.gov (United States)

    Eliazar, Iddo I; Sokolov, Igor M

    2010-01-01

    Populations represented by collections of points scattered randomly on the real line are ubiquitous in science and engineering. The statistical modeling of such populations leads naturally to Poissonian populations-Poisson processes on the real line with a distinguished maximal point. Poissonian populations are infinite objects underlying key issues in statistical physics, probability theory, and random fractals. Due to their infiniteness, measuring the diversity of Poissonian populations depends on the lower-bound cut-off applied. This research characterizes the classes of Poissonian populations whose diversities are invariant with respect to the cut-off level applied and establishes an elemental connection between these classes and extreme-value theory. The measures of diversity considered are variance and dispersion, Simpson's index and inverse participation ratio, Shannon's entropy and Rényi's entropy, and Gini's index.

  13. Diversity and leadership.

    Science.gov (United States)

    Chin, Jean Lau; Sanchez-Hucles, Janis

    2007-09-01

    Comments on the six articles contained in the special issue of the American Psychologist (January 2007) devoted to leadership, written by W. Bennis; S. J. Zaccaro; V. H. Vroom and A. G. Yago; B. J. Avolio; R. J. Sternberg; and R. J. Hackman and R. Wageman. The current authors express concern that the special issue failed to include attention to issues of diversity and intersecting identities as they pertain to leadership. A Special Issue Part II on Diversity and Leadership is being proposed to (a) advance new models of leadership, (b) expand on existing leadership theories, and (c) incorporate diversity and multiple identities in the formulation of more inclusive leadership research and theory. The goal of this special issue will be to revise our theories of leadership and our understanding of effective leadership to include gender, racial/ethnic minority status, sexual orientation, and disability status.

  14. An Algorithmic Diversity Diet?

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk; Schmidt, Jan-Hinrik

    2016-01-01

    With the growing influence of personalized algorithmic recommender systems on the exposure of media content to users, the relevance of discussing the diversity of recommendations increases, particularly as far as public service media (PSM) is concerned. An imagined implementation of a diversity...... diet system however triggers not only the classic discussion of the reach – distinctiveness balance for PSM, but also shows that ‘diversity’ is understood very differently in algorithmic recommender system communities than it is editorially and politically in the context of PSM. The design...... of a diversity diet system generates questions not just about editorial power, personal freedom and techno-paternalism, but also about the embedded politics of recommender systems as well as the human skills affiliated with PSM editorial work and the nature of PSM content....

  15. Diverse by Default

    DEFF Research Database (Denmark)

    Holck, Lotte

    arguments that arise from migrants’ paradoxical situation. To improve their situation, the article discusses whether alternative conceptualization of talents, ‘high potentials’, and making the ambitions of diverse employees more prominent in strategic human resource management can be a relavant strategy......: Employing highlyskilled, career-minded migrants in low-skilled postions, migrants are simultaneously casted as a disposable, replicable and temporary resource, the ‘ideal worker’, AND as a ‘high potential’ for first line management. This extended business case of diversity draws on multifaceted business......This paper contributes to theoretical debates around migrant workers at the workplace, labour market inequality and the business case of diversity. Building on stories of overqualified migrant stuck in low-rank jobs due to their migration, this paper explores how migrant workers are simultaneous...

  16. 7 CFR 52.1850 - Sizes of raisins with seeds-except layer or cluster.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Sizes of raisins with seeds-except layer or cluster... Raisins 1 Type III-Raisins with Seeds § 52.1850 Sizes of raisins with seeds—except layer or cluster. The sizes of Raisins with Seeds—except for Layer or Cluster Raisins with Seeds, are not incorporated in the...

  17. 26 CFR 1.79-2 - Exceptions to the rule of inclusion.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Exceptions to the rule of inclusion. 1.79-2... Exceptions to the rule of inclusion. (a) In general. (1) Section 79(b) provides exceptions for the cost of... he continued in employment) to retire without disability and without the consent of his employer and...

  18. 49 CFR 173.159a - Exceptions for non-spillable batteries.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Exceptions for non-spillable batteries. 173.159a... Class 1 and Class 7 § 173.159a Exceptions for non-spillable batteries. (a) Exceptions for hazardous...-spillable batteries offered for transportation or transported in accordance with this section are subject to...

  19. Danish Exceptionalism: Explaining the Unique Increase in Social Trust over the Past 30 Years

    DEFF Research Database (Denmark)

    Sønderskov, Kim Mannemar; Dinesen, Peter Thisted

    Given the positive societal consequences of social trust and the exceptional high levels of trust found in the Nordic countries there is a growing interest in the background for Nordic trust exceptionalism. Reflecting the debate about the roots of trust, the question is whether this exceptionalism...

  20. Fungal biogeography. Global diversity and geography of soil fungi.

    Science.gov (United States)

    Tedersoo, Leho; Bahram, Mohammad; Põlme, Sergei; Kõljalg, Urmas; Yorou, Nourou S; Wijesundera, Ravi; Villarreal Ruiz, Luis; Vasco-Palacios, Aída M; Thu, Pham Quang; Suija, Ave; Smith, Matthew E; Sharp, Cathy; Saluveer, Erki; Saitta, Alessandro; Rosas, Miguel; Riit, Taavi; Ratkowsky, David; Pritsch, Karin; Põldmaa, Kadri; Piepenbring, Meike; Phosri, Cherdchai; Peterson, Marko; Parts, Kaarin; Pärtel, Kadri; Otsing, Eveli; Nouhra, Eduardo; Njouonkou, André L; Nilsson, R Henrik; Morgado, Luis N; Mayor, Jordan; May, Tom W; Majuakim, Luiza; Lodge, D Jean; Lee, Su See; Larsson, Karl-Henrik; Kohout, Petr; Hosaka, Kentaro; Hiiesalu, Indrek; Henkel, Terry W; Harend, Helery; Guo, Liang-dong; Greslebin, Alina; Grelet, Gwen; Geml, Jozsef; Gates, Genevieve; Dunstan, William; Dunk, Chris; Drenkhan, Rein; Dearnaley, John; De Kesel, André; Dang, Tan; Chen, Xin; Buegger, Franz; Brearley, Francis Q; Bonito, Gregory; Anslan, Sten; Abell, Sandra; Abarenkov, Kessy

    2014-11-28

    Fungi play major roles in ecosystem processes, but the determinants of fungal diversity and biogeographic patterns remain poorly understood. Using DNA metabarcoding data from hundreds of globally distributed soil samples, we demonstrate that fungal richness is decoupled from plant diversity. The plant-to-fungus richness ratio declines exponentially toward the poles. Climatic factors, followed by edaphic and spatial variables, constitute the best predictors of fungal richness and community composition at the global scale. Fungi show similar latitudinal diversity gradients to other organisms, with several notable exceptions. These findings advance our understanding of global fungal diversity patterns and permit integration of fungi into a general macroecological framework. Copyright © 2014, American Association for the Advancement of Science.

  1. Diversity as strategy.

    Science.gov (United States)

    Thomas, David A

    2004-09-01

    IBM's turnaround in the last decade is an impressive and well-documented business story. But behind that success is a less told people story, which explains how the corporation dramatically altered its already diverse composition and created millions of dollars in new business. By the time Lou Gerstner took the helm in 1993, IBM had a long history of progressive management when it came to civil rights and equal-opportunity employment. But Gerstner felt IBM wasn't taking full advantage of a diverse market for talent, nor was it maximizing the potential of its diverse customer and employee base. So in 1995, he launched a diversity task force initiative to uncover and understand differences among people within the organization and find ways to appeal to an even broader set of employees and customers. Gerstner established a task force for each of eight constituencies: Asians; blacks; the gay, lesbian, bisexual, transgendered community; Hispanics; white men; Native Americans; people with disabilities; and women. He asked the task forces to research four questions: What does your constituency need to feel welcome and valued at IBM? What can the corporation do, in partnership with your group, to maximize your constituency's productivity? What can the corporation do to influence your constituency's buying decisions so that IBM is seen as a preferred solution provider? And with which external organizations should IBM form relationships to better understand the needs of your constituency? The answers to these questions became the basis for IBM's diversity strategy. Thomas stresses that four factors are key to implementing any major change initiative: strong support from company leaders, an employee base that is fully engaged with the initiative, management practices that are integrated and aligned with the effort, and a strong and well-articulated business case for action. All four elements have helped IBM make diversity a key corporate strategy tied to real growth.

  2. Diversity and Difference Research

    DEFF Research Database (Denmark)

    Risberg, Annette; Pilhofer, Katharina

    2018-01-01

    In the paper, we reflect on power aspects of categories, and the implications of using pre-established categories in diversity and difference research. With inspiration from intersectionality we discuss how categories and categorization can contribute to continue patterns of inequality and discri......In the paper, we reflect on power aspects of categories, and the implications of using pre-established categories in diversity and difference research. With inspiration from intersectionality we discuss how categories and categorization can contribute to continue patterns of inequality...

  3. Media Pluralism and Diversity

    DEFF Research Database (Denmark)

    In the western world, a diverse and pluralistic media landscape is deemed essential for democracy. But how universal is media pluralism as a concept underpinning media policies? To what extent do normative approaches, regulatory dimensions and monitoring systems differ throughout the world......? Adopting a truly global, theoretical and multidisciplinary perspective, Media Pluralism and Diversity advances our understanding of media pluralism across the globe. It compares metrics developed in different parts of the world to assess levels of, or threats to, media pluralism. It identifies common...

  4. Authoritarian Disbeliefs in Diversity.

    Science.gov (United States)

    Asbrock, Frank; Kauff, Mathias

    2015-01-01

    Ethnic diversity poses a threat to authoritarians, as it indicates non-conformism to group norms and poses a threat to group conformity. According to authoritarian dynamic theory, threats elicit authoritarian reactions in people with authoritarian predispositions. In the present article we tested a mediation model derived from authoritarian dynamic theory in a sample of 171 students. As expected, authoritarian predisposition negatively predicted diversity beliefs. This effect was fully mediated by an authoritarian manifestation, that is, authoritarian aggression. The two other components of right-wing authoritarianism, authoritarian submission and conventionalism, did not mediate the effect. Results confirm contemporary research on authoritarianism and the differentiation of authoritarian predispositions and its manifestations.

  5. Evolution of Anolis lizard dewlap diversity.

    Directory of Open Access Journals (Sweden)

    Kirsten E Nicholson

    Full Text Available BACKGROUND: The dewlaps of Anolis lizards provide a classic example of a complex signaling system whose function and evolution is poorly understood. Dewlaps are flaps of skin beneath the chin that are extended and combined with head and body movements for visual signals and displays. They exhibit extensive morphological variation and are one of two cladistic features uniting anoles, yet little is known regarding their function and evolution. We quantified the diversity of anole dewlaps, investigated whether dewlap morphology was informative regarding phylogenetic relationships, and tested two separate hypotheses: (A similar Anolis habitat specialists possess similar dewlap configurations (Ecomorph Convergence hypothesis, and (B sympatric species differ in their dewlap morphologies to a greater extent than expected by chance (Species Recognition hypothesis. METHODOLOGY/PRINCIPAL FINDINGS: We found that dewlap configurations (sizes, patterns and colors exhibit substantial diversity, but that most are easily categorized into six patterns that incorporate one to three of 13 recognizable colors. Dewlap morphology is not phylogenetically informative and, like other features of anoles, exhibits convergence in configurations. We found no support for the Ecomorph Convergence hypothesis; species using the same structural habitat were no more similar in dewlap configuration than expected by chance. With one exception, all sympatric species in four communities differ in dewlap configuration. However, this provides only weak support for the Species Recognition hypothesis because, due to the great diversity in dewlap configurations observed across each island, few cases of sympatric species with identical dewlaps would be expected to co-occur by chance alone. CONCLUSIONS/SIGNIFICANCE: Despite previous thought, most dewlaps exhibit easily characterizable patterns and colorations. Nevertheless, dewlap variation is extensive and explanations for the origin and

  6. The interplay of diversity training and diversity beliefs on team creativity in nationality diverse teams.

    Science.gov (United States)

    Homan, Astrid C; Buengeler, Claudia; Eckhoff, Robert A; van Ginkel, Wendy P; Voelpel, Sven C

    2015-09-01

    Attaining value from nationality diversity requires active diversity management, which organizations often employ in the form of diversity training programs. Interestingly, however, the previously reported effects of diversity training are often weak and, sometimes, even negative. This situation calls for research on the conditions under which diversity training helps or harms teams. We propose that diversity training can increase team creativity, but only for teams with less positive pretraining diversity beliefs (i.e., teams with a greater need for such training) and that are sufficiently diverse in nationality. Comparing the creativity of teams that attended nationality diversity training versus control training, we found that for teams with less positive diversity beliefs, diversity training increased creative performance when the team's nationality diversity was high, but undermined creativity when the team's nationality diversity was low. Diversity training had less impact on teams with more positive diversity beliefs, and training effects were not contingent upon these teams' diversity. Speaking to the underlying process, we showed that these interactive effects were driven by the experienced team efficacy of the team members. We discuss theoretical and practical implications for nationality diversity management. (c) 2015 APA, all rights reserved).

  7. The diversity of Indian Ocean Heterotardigrada

    Directory of Open Access Journals (Sweden)

    Roberto SANDULLI

    2007-09-01

    Full Text Available Information about Indian Ocean tardigrades is quite scarce and in most cases refers to species in coastal coralline sediment and occasionally in abyssal mud. The present data concern species found in the intertidal sand of Coco and La Digue Islands in the Seychelles, previously unsampled for tardigrades, as well as species in subtidal sediment found at depths ranging between 1 and 60 m off the shores of the Maldive Atolls. These sediments are all very similar and consist of heterogeneous coralline sand, moderately or scarcely sorted. Sixteen species (three new to science were found in the Seychelles, belonging to Renaudarctidae, Stygarctidae, Halechiniscidae, Batillipedidae and Echiniscoididae. Diversity and evenness data are also interesting, with maximum values of H' = 2.59 and of J = 0.97. In the Maldives 25 species were found (two new to science belonging to Neostygarctidae, Stygarctidae, Halechiniscidae and Batillipedidae. Such a number of species, despite the low percentage of tardigrade fauna (only 0.6% of the total meiofauna, contributes to the high values of both diversity and evenness, with H' ranging between 1.5 and 2.6 and J between 0.6 and 1. The Indian Ocean tardigrade fauna currently numbers 31 species of Arthrotardigrada and 2 species of Echiniscoidida. In the present study, Arthrotardigrada are the most abundant and all the families are present except Neoarctidae. Halechiniscidae is present with all the sub-families (except Euclavartinae, thus contributing to the high diversity values. Furthermore, 18 species, representing more than 50% of the total marine tardigrade fauna, are new records for the Indian Ocean, including five species new to science.

  8. Increasing diversity in radiologic technology.

    Science.gov (United States)

    Carwile, Laura

    2003-01-01

    Diversity is increasingly important in the radiologic technology workplace. For significant changes to occur in work force diversity, educators must first recruit and retain students from a wide variety of backgrounds. This article examines personality, race and gender as factors affecting career choice and how educators can use these factors to increase diversity in their programs. An overview of the ASRT's efforts to improve diversity within the profession is presented, along with suggestions for developing effective recruitment and retention plans to increase diversity.

  9. Meeting diversity in ergonomics

    NARCIS (Netherlands)

    Pikaar, R.N.; Koningsveld, E.A.P.; Settels, P.J.M.

    2007-01-01

    Key Features: Offers the conceptual tools for creating more adaptable ergonomic designs to meet the needs of diverse human populations, Unlock the strategic business value found in ergonomically safe and comfortable products, Learn from in-depth case studies how ergonomic intervention was

  10. Diversity Networking Reception

    Science.gov (United States)

    2014-03-01

    Join us at the APS Diversity Reception to relax, network with colleagues, and learn about programs and initiatives for women, underrepresented minorities, and LGBT physicists. You'll have a great time meeting friends in a supportive environment and making connections.

  11. The value of diversity

    International Nuclear Information System (INIS)

    Jones, P.M.S.

    1994-01-01

    Although the adoption of a range of fuels employing different technologies incurs extra cost, diversity can provide a measure of security against supply disruption, fuel price escalation and environmental regulatory changes. Attempts to set a value to diversity in the United Kingdom are reviewed. Most of these have explored the economic impact of different mixes of fuels and/or technologies against a series of postulated fuel price and energy demand scenarios. They depend on the reliability of the cost and technical performance inputs, and subjective judgements about future price and demand developments; these factors undermine confidence in quantitative outputs of such methods. The novel approach of Stirling is presented. This seeks to derive an optimum plant/fuel mix using generation costs for a wide range of options and a marginal value for incremental changes in diversity, based on a specified diversity index. Stirling's approach could be argued to support the maintenance or expansion of the existing nuclear component of United Kingdom power supplies and an increase in the contribution from renewables. However, problems within the method which is still under development limits the weight that can be attached to its findings at present. Given the closely comparable financial costs, a reasonable balance at this time would seem to consist of the available level of low cost renewables and roughly equal tranches of gas, nuclear and coal. A smaller coal-fired component would be appropriate if environmental costs are taken into account. (19 references). (UK)

  12. Diversity of Journalisms

    NARCIS (Netherlands)

    Ramon Salavaria (ed.)

    2011-01-01

    These Proceedings gather the research works presented to the Conference “Diversity of Journalisms: Shaping Complex Media Landscapes”, held in Pamplona (Spain), the 4th and 5th of July, 2011. This event was co-organised by ECREA Journalism Studies Section and the School of Communication of the

  13. What Is Diversity Pedagogy?

    Science.gov (United States)

    Sheets, Rosa Hernandez

    2009-01-01

    Diversity Pedagogy Theory (DPT) is a set of principles that point out the natural and inseparable connection between culture and cognition. In other words, to be effective as a teacher, he/she must understand and acknowledge the critical role culture plays in the teaching-learning process. DPT maintains that culturally inclusive teachers (a)…

  14. Composition: Unity - Diversity series

    DEFF Research Database (Denmark)

    Bergstrøm-Nielsen, Carl

    2015-01-01

    Unity-Diversity series are open compositions to be realised by improvising musicians. See more about my composition practise in the entry "Composition - General Introduction". This work is licensed under a Creative Commons "by-nc" License. You may for non-commercial purposes use and distribute it...

  15. Measuring Cultural Diversity

    DEFF Research Database (Denmark)

    Patsiurko, Natalka; Campbell, John L.; Hall, John A.

    2012-01-01

    Many claim that national economic success depends upon cultural homogeneity. We collect new time-series data and develop new measures of ethnic, linguistic and religious fractionalization for the OECD countries. We show that cultural diversity may vary by type across countries and over short peri...

  16. Human diversity in images

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    A photo contest is being jointly organized by the CERN Equal Opportunities team and the CERN Photo Club. All you need to do is submit a photo or quotation. The contest is open to everyone.   Diversity at CERN You don’t need to be a photographer or to have sophisticated photographic equipment to capture CERN’s diversity of working styles, gender, age, ethnic, origin and physical ability. Its many facets are all around you! The emphasis of the initiative is on capturing this diversity in an image using creativity, intuition and cultural empathy. You can also contribute with a quotation (whether or not you specify who said it is optional) telling the organizers what strikes you about diversity at CERN. The photo entries and a collection of the quotations will be displayed in an exhibition to be held in May in the Main Building, as well as on the CERN Photo Club website. The best photos will be awarded prizes. So over to you: dig deep inside human nature, explore individual tal...

  17. Strength in diversity

    CERN Multimedia

    2012-01-01

    Diversity has always been science’s big secret, yet it’s a secret we’ve always been keen to share. CERN was founded on the basis of bringing a diverse mix of people together to pursue common aims, and it’s one of the things that’s driven this Organization’s success over the decades.   Now, we are launching a new diversity programme aimed at strengthening our tradition of inclusiveness. This programme is being launched with a range of key goals in mind for the 2012-2014 timeframe. We’ll be striving to achieve a fair gender balance across all professional categories, and to provide strong gender role models across the Organization. We’ll be improving our career development processes to allow people to progress through both technical and managerial pathways, and we’ll be re-launching workshops that bring people from diverse professions and generations together to share their experience on key aspects of lif...

  18. Religious diversity and pluralism

    DEFF Research Database (Denmark)

    Ahlin, Lars; Borup, Jørn; Fibiger, Marianne Qvortrup

    2012-01-01

    . Religious diversity has grown in Denmark with the arrival of new immigrant groups and with new forms and interpretations of traditional religious and spiritual traditions. More importantly, the relations and interactions between religious groups -- the hallmarks of religious pluralism -- are still incipient...

  19. Diversity without representation

    CSIR Research Space (South Africa)

    Scholes, RJ

    2006-07-01

    Full Text Available Since the 1992 United Nations ‘Earth Summit’ conference in Rio de Janeiro, Brazil, biodiversity has received increasing attention from scientists, governments and the public worldwide. There is growing recognition that the diversity of life on Earth...

  20. Narrating Peoplehood amidst Diversity

    DEFF Research Database (Denmark)

    Böss, Michael

    In Narrating Peoplehood amidst Diversity, 16 internationally renowned scholars reflect on the nature and history of peoplehood and discuss how narratives inform national identities, public culture and academic historiography. The book is a timely contribution to the ongoing debate on belonging...

  1. The Diverse Generation.

    Science.gov (United States)

    Howe, Neil; Strauss, Bill

    1993-01-01

    In this era of multiculturalism, young people find diversity so heavily emphasized that they may wonder whether centrifugal group loyalties may tear the nation apart. Most people born between 1961 and 1981 believe that they handle racial problems better than their elders did. (SLD)

  2. Meeting diversity in ergonomics

    NARCIS (Netherlands)

    Looze, M.P. de; Pikaar, R.

    2006-01-01

    The plenary lectures from the 16th World Congress on Ergonomics, Maastricht, July 10-14, 2006, have been documented in this special issue. Its theme was ‘Meeting Diversity'. The contributions, ranging from scientific papers to technical notes or short statements, cover different aspects of the

  3. Managing Diverse Stakeholders

    OpenAIRE

    Pipkin, Erin; Porter, Sean; Clark, Rickie

    2017-01-01

    For every public project, there is a diverse group of stakeholders who need and want information. During this session we outline important stakeholders, how and when to involve them in the planning process, and how targeted messaging might be the key to your project’s success. We also discuss how to identify and manage stakeholders who oppose your project.

  4. Life: Complexity and Diversity

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 1; Issue 4. Life : Complexity and Diversity Growing Larger. Madhav Gadgil. Series Article Volume 1 Issue 4 April 1996 pp 15-22. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/001/04/0015-0022 ...

  5. Education and Diversity

    Science.gov (United States)

    Banks, James A.; Cookson, Peter; Gay, Geneva; Hawley, Willis D.; Irvine, Jacqueline Jordan; Nieto, Sonia; Schofield, Janet Ward; Stephan, Walter G.

    2005-01-01

    What do we know about education and diversity, and how do we know it? This two-part question guided the work of the Multicultural Education Consensus Panel, which included the eight scholars named above. The panel's work was sponsored by the Center for Multicultural Education at the University of Washington and the Common Destiny Alliance at the…

  6. How Symbiosis Creates Diversity

    Science.gov (United States)

    Lord, Joshua

    2010-01-01

    Diversity in habitats on Earth is astounding--whether on land or in the sea--and this is in part due to symbiosis. The lesson described in this article helps students understand how symbiosis affects different organisms through a fun and engaging game where they match hosts and symbionts based on their respective needs. This 45-minute lesson is…

  7. Large-Scale Spatio-Temporal Patterns of Mediterranean Cephalopod Diversity.

    Directory of Open Access Journals (Sweden)

    Stefanie Keller

    Full Text Available Species diversity is widely recognized as an important trait of ecosystems' functioning and resilience. Understanding the causes of diversity patterns and their interaction with the environmental conditions is essential in order to effectively assess and preserve existing diversity. While diversity patterns of most recurrent groups such as fish are commonly studied, other important taxa such as cephalopods have received less attention. In this work we present spatio-temporal trends of cephalopod diversity across the entire Mediterranean Sea during the last 19 years, analysing data from the annual bottom trawl survey MEDITS conducted by 5 different Mediterranean countries using standardized gears and sampling protocols. The influence of local and regional environmental variability in different Mediterranean regions is analysed applying generalized additive models, using species richness and the Shannon Wiener index as diversity descriptors. While the western basin showed a high diversity, our analyses do not support a steady eastward decrease of diversity as proposed in some previous studies. Instead, high Shannon diversity was also found in the Adriatic and Aegean Seas, and high species richness in the eastern Ionian Sea. Overall diversity did not show any consistent trend over the last two decades. Except in the Adriatic Sea, diversity showed a hump-shaped trend with depth in all regions, being highest between 200-400 m depth. Our results indicate that high Chlorophyll a concentrations and warmer temperatures seem to enhance species diversity, and the influence of these parameters is stronger for richness than for Shannon diversity.

  8. Evaluating the Effectiveness of an Antimicrobial Stewardship Program on Reducing the Incidence Rate of Healthcare-Associated Clostridium difficile Infection: A Non-Randomized, Stepped Wedge, Single-Site, Observational Study.

    Science.gov (United States)

    DiDiodato, Giulio; McArthur, Leslie

    2016-01-01

    The incidence rate of healthcare-associated Clostridium difficile infection (HA-CDI) is estimated at 1 in 100 patients. Antibiotic exposure is the most consistently reported risk factor for HA-CDI. Strategies to reduce the risk of HA-CDI have focused on reducing antibiotic utilization. Prospective audit and feedback is a commonly used antimicrobial stewardship intervention (ASi). The impact of this ASi on risk of HA-CDI is equivocal. This study examines the effectiveness of a prospective audit and feedback ASi on reducing the risk of HA-CDI. Single-site, 339 bed community-hospital in Barrie, Ontario, Canada. Primary outcome is HA-CDI incidence rate. Daily prospective and audit ASi is the exposure variable. ASi implemented across 6 wards in a non-randomized, stepped wedge design. Criteria for ASi; any intravenous antibiotic use for ≥ 48 hrs, any oral fluoroquinolone or oral second generation cephalosporin use for ≥ 48 hrs, or any antimicrobial use for ≥ 5 days. HA-CDI cases and model covariates were aggregated by ward, year and month starting September 2008 and ending February 2016. Multi-level mixed effect negative binomial regression analysis was used to model the primary outcome, with intercept and slope coefficients for ward-level random effects estimated. Other covariates tested for inclusion in the final model were derived from previously published risk factors. Deviance residuals were used to assess the model's goodness-of-fit. The dataset included 486 observation periods, of which 350 were control periods and 136 were intervention periods. After accounting for all other model covariates, the estimated overall ASi incidence rate ratio (IRR) was 0.48 (95% 0.30, 0.79). The ASi effect was independent of antimicrobial utilization. The ASi did not seem to reduce the risk of Clostridium difficile infection on the surgery wards (IRR 0.87, 95% CI 0.45, 1.69) compared to the medicine wards (IRR 0.42, 95% CI 0.28, 0.63). The ward-level burden of Clostridium

  9. Evaluating the Effectiveness of an Antimicrobial Stewardship Program on Reducing the Incidence Rate of Healthcare-Associated Clostridium difficile Infection: A Non-Randomized, Stepped Wedge, Single-Site, Observational Study.

    Directory of Open Access Journals (Sweden)

    Giulio DiDiodato

    Full Text Available The incidence rate of healthcare-associated Clostridium difficile infection (HA-CDI is estimated at 1 in 100 patients. Antibiotic exposure is the most consistently reported risk factor for HA-CDI. Strategies to reduce the risk of HA-CDI have focused on reducing antibiotic utilization. Prospective audit and feedback is a commonly used antimicrobial stewardship intervention (ASi. The impact of this ASi on risk of HA-CDI is equivocal. This study examines the effectiveness of a prospective audit and feedback ASi on reducing the risk of HA-CDI.Single-site, 339 bed community-hospital in Barrie, Ontario, Canada. Primary outcome is HA-CDI incidence rate. Daily prospective and audit ASi is the exposure variable. ASi implemented across 6 wards in a non-randomized, stepped wedge design. Criteria for ASi; any intravenous antibiotic use for ≥ 48 hrs, any oral fluoroquinolone or oral second generation cephalosporin use for ≥ 48 hrs, or any antimicrobial use for ≥ 5 days. HA-CDI cases and model covariates were aggregated by ward, year and month starting September 2008 and ending February 2016. Multi-level mixed effect negative binomial regression analysis was used to model the primary outcome, with intercept and slope coefficients for ward-level random effects estimated. Other covariates tested for inclusion in the final model were derived from previously published risk factors. Deviance residuals were used to assess the model's goodness-of-fit.The dataset included 486 observation periods, of which 350 were control periods and 136 were intervention periods. After accounting for all other model covariates, the estimated overall ASi incidence rate ratio (IRR was 0.48 (95% 0.30, 0.79. The ASi effect was independent of antimicrobial utilization. The ASi did not seem to reduce the risk of Clostridium difficile infection on the surgery wards (IRR 0.87, 95% CI 0.45, 1.69 compared to the medicine wards (IRR 0.42, 95% CI 0.28, 0.63. The ward-level burden of

  10. Valuing gender diversity in teams

    DEFF Research Database (Denmark)

    Lauring, Jakob; Villeseche, Florence

    2015-01-01

    Team gender diversity has been much debated in many different contexts – not least since the search for a main effect of diversity on performance was launched. However, results have so far been inconclusive, and a number of scholars suggest that more attention should be directed at contextual...... factors which could influence the effect of gender diversity on team performance. In this study, we explore the effect of positive diversity attitudes and assess the degree of gender diversity where such group attitudes have greater impact. This is done by using a sample of 1085 leaders of academic...... research teams. Findings show that positive diversity attitude in the form of group openness to diversity is strongly associated with team performance. We also find a moderating effect of gender diversity meaning that the effect of openness to diversity is stronger when gender groups are more balanced...

  11. Equal opportunities in diversity

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    Promoting equal opportunities at CERN and advising the Director-General on all related matters is the task of the Equal Opportunities Officer, Doris Chromek-Burckhart, and Tim Smith, chair of the Equal Opportunities Advisory Panel. Changes are being introduced: in future, the focus of their work will be broadened to cover all aspects of diversity promotion.   The term "equal opportunities" has always been broader in scope than the equal treatment of men and women but this is what it has traditionally been confined to in practice. "We wanted to change how people see our mission", explains Doris Chromek-Burckhart. The word "diversity" has much wider connotations than "equal opportunities" and makes it clearer that we are also dealing with differences in nationality, religion, age, culture and physical ability”. Getting away from the old clichés is vital to ensuring equal treatment for everyone. The diversit...

  12. Desired Diversity and Symptomatic Anxiety

    DEFF Research Database (Denmark)

    Friis Christensen, Jannick; Muhr, Sara Louise

    2018-01-01

    of diversity that, however, constantly change due to the empty form of diversity. Anxiety manifests itself in the obsession of unobtainable idealised forms of diversity as well as in the uncertainty associated with the traumatic experience of always falling short of what is desired in an object...... – the experience of failed diversity. Conclusively, we discuss the productive potential of the power of lack. The impossibility of diversity is what, at once, conditions the possibility of diversity. We therefore suggest that the symptomatic anxiety provoked by the lack should be enjoyed in order to engage...

  13. International diversity management

    DEFF Research Database (Denmark)

    Lauring, Jakob

    2013-01-01

    challenges in balancing between global integration and local responsiveness. The aim of this paper is to illustrate some of the central problems that multinational corporations need to deal with when transferring diversity management practices from headquarters to local subsidiaries. This is illustrated...... by the results of an ethnographic field study on Danish expatriates in a Saudi subsidiary. Implications of the findings are discussed in detail....

  14. Diversity and Cooperation

    OpenAIRE

    Bruner, Justin Pearce

    2014-01-01

    The present dissertation is an exploration of the effect of diversity on social contract formation and the evolution of cooperation. This work stems from the pioneering efforts of economist Arthur Robson, who first explored the role of costless pre-game communication in strategic interactions. When communication is permitted, individuals playing a game can condition their behavior on the signal received from their counterpart. For my purposes, I interpret these signals as racial markers or cu...

  15. Diverse Image Annotation

    KAUST Repository

    Wu, Baoyuan

    2017-11-09

    In this work we study the task of image annotation, of which the goal is to describe an image using a few tags. Instead of predicting the full list of tags, here we target for providing a short list of tags under a limited number (e.g., 3), to cover as much information as possible of the image. The tags in such a short list should be representative and diverse. It means they are required to be not only corresponding to the contents of the image, but also be different to each other. To this end, we treat the image annotation as a subset selection problem based on the conditional determinantal point process (DPP) model, which formulates the representation and diversity jointly. We further explore the semantic hierarchy and synonyms among the candidate tags, and require that two tags in a semantic hierarchy or in a pair of synonyms should not be selected simultaneously. This requirement is then embedded into the sampling algorithm according to the learned conditional DPP model. Besides, we find that traditional metrics for image annotation (e.g., precision, recall and F1 score) only consider the representation, but ignore the diversity. Thus we propose new metrics to evaluate the quality of the selected subset (i.e., the tag list), based on the semantic hierarchy and synonyms. Human study through Amazon Mechanical Turk verifies that the proposed metrics are more close to the humans judgment than traditional metrics. Experiments on two benchmark datasets show that the proposed method can produce more representative and diverse tags, compared with existing image annotation methods.

  16. Diverse Image Annotation

    KAUST Repository

    Wu, Baoyuan; Jia, Fan; Liu, Wei; Ghanem, Bernard

    2017-01-01

    In this work we study the task of image annotation, of which the goal is to describe an image using a few tags. Instead of predicting the full list of tags, here we target for providing a short list of tags under a limited number (e.g., 3), to cover as much information as possible of the image. The tags in such a short list should be representative and diverse. It means they are required to be not only corresponding to the contents of the image, but also be different to each other. To this end, we treat the image annotation as a subset selection problem based on the conditional determinantal point process (DPP) model, which formulates the representation and diversity jointly. We further explore the semantic hierarchy and synonyms among the candidate tags, and require that two tags in a semantic hierarchy or in a pair of synonyms should not be selected simultaneously. This requirement is then embedded into the sampling algorithm according to the learned conditional DPP model. Besides, we find that traditional metrics for image annotation (e.g., precision, recall and F1 score) only consider the representation, but ignore the diversity. Thus we propose new metrics to evaluate the quality of the selected subset (i.e., the tag list), based on the semantic hierarchy and synonyms. Human study through Amazon Mechanical Turk verifies that the proposed metrics are more close to the humans judgment than traditional metrics. Experiments on two benchmark datasets show that the proposed method can produce more representative and diverse tags, compared with existing image annotation methods.

  17. Diversity: The Business Case?

    Science.gov (United States)

    Jones, B.

    2013-12-01

    Understanding perceptions and managing expectations are learnable skills that do not necessarily come with project funding. Finding life balance as one moves through a STEM career path poses unique challenges that require a certain skill set that is not always intuitive. Some of those challenges include: selecting grad or post doc positions; balancing work and family commitments; and dealing with employer/advisor perceptions and expectations. As in nature, the STEM enterprise requires multiple perspectives to flourish (necessity of peer review), and in a changing environment (e.g., budget, generations, technology, etc.), embracing diversity in thought and application may help drive the evolution of STEM in the U.S. Many Agencies and organizations have ';workforce development' programs that focus on preparing the next generation of scientists and engineers at the graduate and undergraduate level that focus on preparing students in the diverse disciplines that are unique to those Agency and organizational missions. While financial support certainly is critical to assist students in Science Technology Engineering and Mathematics (STEM) and other fields, professional development is just as important to equip students with a balanced arsenal of tactics to be successful professionals in the STEM workforce of today. Success in these efforts requires an honest look at the issue of inequality in the STEM ecosystem... meaning, what initiatives have been successful in addressing the imbalance in sources of thought and application, therefore promoting the importance of diversity.

  18. Celebrating diversity at CERN

    CERN Multimedia

    2014-01-01

    With international women’s day coming up on 8 March, along with the recent appointment of a new Diversity Programme Leader, it seems timely to take a look at how far we’ve come over recent years in promoting gender equality at CERN. In short, the news is good, but we still have some way to travel.   CERN does not have a policy of positive discrimination, but rather one of presenting a level playing field. We work to ensure, for example, that the diversity of candidates presented for interview reflects the diversity of applicants. It’s an approach that is having the desired effect. Overall, the percentage of female staff members has risen from 17% to 20% over the last decade, with parity being achieved among professional administrators and significant advances being made among research and applied physicists, engineers and technicians. At recruitment, our approach is working: we’re managing to attract growing numbers of women. This brings us to the phen...

  19. An Exploitability Analysis Technique for Binary Vulnerability Based on Automatic Exception Suppression

    Directory of Open Access Journals (Sweden)

    Zhiyuan Jiang

    2018-01-01

    Full Text Available To quickly verify and fix vulnerabilities, it is necessary to judge the exploitability of the massive crash generated by the automated vulnerability mining tool. While the current manual analysis of the crash process is inefficient and time-consuming, the existing automated tools can only handle execute exceptions and some write exceptions but cannot handle common read exceptions. To address this problem, we propose a method of determining the exploitability based on the exception type suppression. This method enables the program to continue to execute until an exploitable exception is triggered. The method performs a symbolic replay of the crash sample, constructing and reusing data gadget, to bypass the complex exception, thereby improving the efficiency and accuracy of vulnerability exploitability analysis. The testing of typical CGC/RHG binary software shows that this method can automatically convert a crash that cannot be judged by existing analysis tools into a different crash type and judge the exploitability successfully.

  20. Equilibrium Bird Species Diversity in Atlantic Islands.

    Science.gov (United States)

    Valente, Luis; Illera, Juan Carlos; Havenstein, Katja; Pallien, Tamara; Etienne, Rampal S; Tiedemann, Ralph

    2017-06-05

    Half a century ago, MacArthur and Wilson proposed that the number of species on islands tends toward a dynamic equilibrium diversity around which species richness fluctuates [1]. The current prevailing view in island biogeography accepts the fundamentals of MacArthur and Wilson's theory [2] but questions whether their prediction of equilibrium can be fulfilled over evolutionary timescales, given the unpredictable and ever-changing nature of island geological and biotic features [3-7]. Here we conduct a complete molecular phylogenetic survey of the terrestrial bird species from four oceanic archipelagos that make up the diverse Macaronesian bioregion-the Azores, the Canary Islands, Cape Verde, and Madeira [8, 9]. We estimate the times at which birds colonized and speciated in the four archipelagos, including many previously unsampled endemic and non-endemic taxa and their closest continental relatives. We develop and fit a new multi-archipelago dynamic stochastic model to these data, explicitly incorporating information from 91 taxa, both extant and extinct. Remarkably, we find that all four archipelagos have independently achieved and maintained a dynamic equilibrium over millions of years. Biogeographical rates are homogeneous across archipelagos, except for the Canary Islands, which exhibit higher speciation and colonization. Our finding that the avian communities of the four Macaronesian archipelagos display an equilibrium diversity pattern indicates that a diversity plateau may be rapidly achieved on islands where rates of in situ radiation are low and extinction is high. This study reveals that equilibrium processes may be more prevalent than recently proposed, supporting MacArthur and Wilson's 50-year-old theory. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Managing a culturally diverse workforce : Diversity perspectives in organizations

    NARCIS (Netherlands)

    Podsiadlowski, Astrid; Gröschke, Daniela; Kogler, Marina; Springer, Cornelia; van der Zee, Karen

    The authors conducted two studies to analyze why and how organizations approach and manage cultural diversity in the Austrian workplace and to identify organizations' diversity perspectives. In Study 1, 29 interviews revealed insights into organizational approaches to diversity and how these

  2. Contrasting diversity patterns of crenarchaeal, bacterial and fungal soil communities in an alpine landscape.

    Directory of Open Access Journals (Sweden)

    Lucie Zinger

    2011-05-01

    Full Text Available The advent of molecular techniques in microbial ecology has aroused interest in gaining an understanding about the spatial distribution of regional pools of soil microbes and the main drivers responsible of these spatial patterns. Here, we assessed the distribution of crenarcheal, bacterial and fungal communities in an alpine landscape displaying high turnover in plant species over short distances. Our aim is to determine the relative contribution of plant species composition, environmental conditions, and geographic isolation on microbial community distribution.Eleven types of habitats that best represent the landscape heterogeneity were investigated. Crenarchaeal, bacterial and fungal communities were described by means of Single Strand Conformation Polymorphism. Relationships between microbial beta diversity patterns were examined by using Bray-Curtis dissimilarities and Principal Coordinate Analyses. Distance-based redundancy analyses and variation partitioning were used to estimate the relative contributions of different drivers on microbial beta diversity. Microbial communities tended to be habitat-specific and did not display significant spatial autocorrelation. Microbial beta diversity correlated with soil pH. Fungal beta-diversity was mainly related to soil organic matter. Though the effect of plant species composition was significant for all microbial groups, it was much stronger for Fungi. In contrast, geographic distances did not have any effect on microbial beta diversity.Microbial communities exhibit non-random spatial patterns of diversity in alpine landscapes. Crenarcheal, bacterial and fungal community turnover is high and associated with plant species composition through different set of soil variables, but is not caused by geographical isolation.

  3. 7 CFR 52.1852 - Grades of raisins with seeds-except layer or cluster.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Grades of raisins with seeds-except layer or cluster... Raisins 1 Type III-Raisins with Seeds § 52.1852 Grades of raisins with seeds—except layer or cluster. (a...—Allowances for Defects in Raisins With Seeds—Except Layer or Cluster Defects U.S. Grade A U.S. Grade B U.S...

  4. Danish Exceptionalism: Explaining the Unique Increase in Social Trust over the Past 30 Years

    DEFF Research Database (Denmark)

    Sønderskov, Kim Mannemar; Dinesen, Peter Thisted

    2014-01-01

    Given the positive societal consequences of social trust and the exceptional high levels of trust found in the Nordic countries, there is a growing interest in the background for Nordic trust exceptionalism. Reflecting the debate about the roots of trust, the question is whether this exceptionalism...... has been a permanent feature of these societies, i.e., an enduring cultural trait, or primarily been shaped by more contemporary experiential forces. This article examines the roots of the present Nordic trust exceptionalism by means of analysing the development of trust in Denmark over the past three...

  5. Invertebrate diversity in southern California

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This shapefile displays mean invertebrate diversity within 5 minute grid cells. The Shannon Index of diversity was calculated from Southern California Coastal Water...

  6. Board diversity in family firms

    OpenAIRE

    Menozzi, Anna; Fraquelli, Giovanni; Novara, Jolanda de

    2015-01-01

    The paper deals with diversity as a key factor to improve the board of directors’ decision process in family firms. The empirical literature about board diversity points at the positive impact of diversity on board functioning and firm performance. The paper uses a statistical diversity index to capture the heterogeneity of board of directors and put it in relation with firm performance, as measured by firm profitability. The empirical analysis is based on a newly collected panel of 327 famil...

  7. Discovering Diversity in Marketing Practice

    OpenAIRE

    Murray, John; O'Driscoll, Aidan; Torres, Ann

    2002-01-01

    Marketing practice varies among firms. However, the prescriptive literature emphasises a universal view of practice, a “one-size-fits-all” view. This paper addresses the issue of explaining diversity in competitive space and over time. Diversity in competitive space reflects the existence of different routes to high performance. Diversity over time reflects some combination of change in the individual firm and change in a population of firms. In the former case, diversity is shaped by organis...

  8. Diversity beyond the Golden Rule.

    Science.gov (United States)

    Carnevale, Anthony P.; Stone, Susan C.

    1994-01-01

    Diversity implies differences in people based on their identifications with various groups and is also a process of acknowledging differences through action. Those organizations that have welcomed diversity are more productive and have a competitive advantage. Diversity training can be awareness based (cognitive) or skill based (behavioral). (JOW)

  9. Diversity in the Workplace. Symposium.

    Science.gov (United States)

    2002

    Three papers comprise this symposium on diversity in the workplace. "Factors That Assist and Barriers That Hinder the Success of Diversity Initiatives in Multinational Corporations" (Rose Mary Wentling) reports that factors that assisted in the success were classified under diversity department, human, and work environment; barriers were…

  10. Diversity - Essential quality for agronomy

    Science.gov (United States)

    Diversity is an essential quality for success in agronomy because agronomy touches everyone, everywhere in some way, and food production is crucial for every society around the world. Consider, for example, our membership, which is diverse in almost every way imaginable. This diversity brings differ...

  11. Estonian exceptionalism

    Index Scriptorium Estoniae

    2011-01-01

    Ulatuslikud kärped ja liitumine eurotsooniga toovad Eestist häid majandusuudiseid: töötus langeb, majandus kasvab, eksport tõuseb, eelarve on plussis, reitinguagentuur Fitch krediidireiting tõusis tasemele A+

  12. Permitted Exceptions

    DEFF Research Database (Denmark)

    Wagner, Anne Margrethe

    This PhD thesis examines the phenomenon of temporary use in a contemporary Northern European planning context. The background for the study is the increasing interest in initiating temporary use projects within urban redevelopment by public authorities, such as municipalities, related sub...

  13. Exceptional indices

    Science.gov (United States)

    Gaiotto, Davide; Razamat, Shlomo S.

    2012-05-01

    Recently a prescription to compute the superconformal index for all theories of class S was proposed. In this paper we discuss some of the physical information which can be extracted from this index. We derive a simple criterion for the given theory of class S to have a decoupled free component and for it to have enhanced flavor symmetry. Furthermore, we establish a criterion for the "good", the "bad", and the "ugly" trichotomy of the theories. After interpreting the prescription to compute the index with non-maximal flavor symmetry as a residue calculus we address the computation of the index of the bad theories. In particular we suggest explicit expressions for the superconformal index of higher rank theories with E n flavor symmetry, i.e. for the Hilbert series of the multi- instanton moduli space of E n .

  14. Exceptional Colloquium

    CERN Multimedia

    DG Unit

    2010-01-01

    16 September 2010 10:00 - Bldg. 222/R-001 Digital scholarship and the changing nature of scientific publication by R.d Holliman & E. Scanlon / Open University, UK Digital media have extended the number of channels that scientists (and other academics) use to communicate and share information. Digital technologies have the potential to make all stages of the research process more visible in the public sphere, and to audiences that have, on occasion, opportunities for interaction and engagement. But digital technologies also are introducing novel demands on researchers, requiring skills and competencies on the part of scientists that are encapsulated by the concept of digital scholarship. In this presentation we explore this developing context via a case study: the publication of emails from the Climatic Research Unit at the University of East Anglia (also known as ‘climategate’). The findings of three reviews of ‘climategate’ will be discussed in terms of their i...

  15. Event detection and exception handling strategies in the ASDEX Upgrade discharge control system

    International Nuclear Information System (INIS)

    Treutterer, W.; Neu, G.; Rapson, C.; Raupp, G.; Zasche, D.; Zehetbauer, T.

    2013-01-01

    Highlights: •Event detection and exception handling is integrated in control system architecture. •Pulse control with local exception handling and pulse supervision with central exception handling are strictly separated. •Local exception handling limits the effect of an exception to a minimal part of the controlled system. •Central Exception Handling solves problems requiring coordinated action of multiple control components. -- Abstract: Thermonuclear plasmas are governed by nonlinear characteristics: plasma operation can be classified into scenarios with pronounced features like L and H-mode, ELMs or MHD activity. Transitions between them may be treated as events. Similarly, technical systems are also subject to events such as failure of measurement sensors, actuator saturation or violation of machine and plant operation limits. Such situations often are handled with a mixture of pulse abortion and iteratively improved pulse schedule reference programming. In case of protection-relevant events, however, the complexity of even a medium-sized device as ASDEX Upgrade requires a sophisticated and coordinated shutdown procedure rather than a simple stop of the pulse. The detection of events and their intelligent handling by the control system has been shown to be valuable also in terms of saving experiment time and cost. This paper outlines how ASDEX Upgrade's discharge control system (DCS) detects events and handles exceptions in two stages: locally and centrally. The goal of local exception handling is to limit the effect of an unexpected or asynchronous event to a minimal part of the controlled system. Thus, local exception handling facilitates robustness to failures but keeps the decision structures lean. A central state machine deals with exceptions requiring coordinated action of multiple control components. DCS implements the state machine by means of pulse schedule segments containing pre-programmed waveforms to define discharge goal and control

  16. Event detection and exception handling strategies in the ASDEX Upgrade discharge control system

    Energy Technology Data Exchange (ETDEWEB)

    Treutterer, W., E-mail: Wolfgang.Treutterer@ipp.mpg.de; Neu, G.; Rapson, C.; Raupp, G.; Zasche, D.; Zehetbauer, T.

    2013-10-15

    Highlights: •Event detection and exception handling is integrated in control system architecture. •Pulse control with local exception handling and pulse supervision with central exception handling are strictly separated. •Local exception handling limits the effect of an exception to a minimal part of the controlled system. •Central Exception Handling solves problems requiring coordinated action of multiple control components. -- Abstract: Thermonuclear plasmas are governed by nonlinear characteristics: plasma operation can be classified into scenarios with pronounced features like L and H-mode, ELMs or MHD activity. Transitions between them may be treated as events. Similarly, technical systems are also subject to events such as failure of measurement sensors, actuator saturation or violation of machine and plant operation limits. Such situations often are handled with a mixture of pulse abortion and iteratively improved pulse schedule reference programming. In case of protection-relevant events, however, the complexity of even a medium-sized device as ASDEX Upgrade requires a sophisticated and coordinated shutdown procedure rather than a simple stop of the pulse. The detection of events and their intelligent handling by the control system has been shown to be valuable also in terms of saving experiment time and cost. This paper outlines how ASDEX Upgrade's discharge control system (DCS) detects events and handles exceptions in two stages: locally and centrally. The goal of local exception handling is to limit the effect of an unexpected or asynchronous event to a minimal part of the controlled system. Thus, local exception handling facilitates robustness to failures but keeps the decision structures lean. A central state machine deals with exceptions requiring coordinated action of multiple control components. DCS implements the state machine by means of pulse schedule segments containing pre-programmed waveforms to define discharge goal and control

  17. Probe-diverse ptychography

    Energy Technology Data Exchange (ETDEWEB)

    Peterson, I., E-mail: isaac.russellpeterson@rmit.edu.au [ARC Centre of Excellence for Coherent X-ray Science, the University of Melbourne, School of Physics, Victoria 3010 (Australia); Harder, R. [Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439 (United States); Robinson, I.K. [Research Complex at Harwell, Didcot, Oxfordshire OX11 0DE (United Kingdom); London Centre for Nanotechnology, University College London, London WC1H 0AH (United Kingdom)

    2016-12-15

    We propose an extension of ptychography where the target sample is scanned separately through several probes with distinct amplitude and phase profiles and a diffraction image is recorded for each probe and each sample translation. The resulting probe-diverse dataset is used to iteratively retrieve high-resolution images of the sample and all probes simultaneously. The method is shown to yield significant improvement in the reconstructed sample image compared to the image obtained using the standard single-probe ptychographic phase-retrieval scheme.

  18. Absorptive Capacity and Diversity

    DEFF Research Database (Denmark)

    Kristinsson, Kári

    overlooked area of research. Although research based on Cohen and Levinthal‘s work has made considerable impact, there is scarcity of research on certain fundamental points argued by Cohen and Levinthal. Among these is the importance of employee diversity as well as the type and nature of interaction between...... design we verify that this relationship is not only a correlation but rather a causal relationship. Fourth, as innovation is in its essence a combination of different knowledge, the pattern and type of communication between individuals, firms and institutions, is an important part of explaining...... innovative behaviour....

  19. Diversity in cancer care

    DEFF Research Database (Denmark)

    Nyholm, Nanna; Halvorsen, Ida; Mygind, Anna

    2018-01-01

    BACKGROUND: The burden of breast cancer is a key challenge for women's health globally. Rehabilitation needs and strategies for living with long-term consequences of breast cancer and its treatment cannot be isolated from the social contexts of patients, including relationships with relatives...... and healthcare professionals. AIM: This study explores how healthcare professionals' categorisations engage with breast cancer patients' social identities in encounters about rehabilitation before hospital discharge. METHOD: We conducted a multiperspective case-based qualitative study at a Danish department...... for a greater focus on improving encounters between breast cancer patients and healthcare professionals to ensure that rehabilitation needs are accommodated for among diverse patient groups....

  20. 41 CFR 60-30.19 - Objections; exceptions; offer of proof.

    Science.gov (United States)

    2010-07-01

    ... exceptions to the Administrative Law Judge's recommendations and conclusions. (c) Offer of proof. An offer of...; offer of proof. 60-30.19 Section 60-30.19 Public Contracts and Property Management Other Provisions... EXECUTIVE ORDER 11246 Hearings and Related Matters § 60-30.19 Objections; exceptions; offer of proof. (a...

  1. 48 CFR 227.7009-3 - Additional clauses-contracts except running royalty contracts.

    Science.gov (United States)

    2010-10-01

    ...-contracts except running royalty contracts. 227.7009-3 Section 227.7009-3 Federal Acquisition Regulations...—contracts except running royalty contracts. The following clauses are examples for use in patent release and settlement agreements, and license agreements not providing for payment by the Government of a running...

  2. 49 CFR 173.420 - Uranium hexafluoride (fissile, fissile excepted and non-fissile).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Uranium hexafluoride (fissile, fissile excepted....420 Uranium hexafluoride (fissile, fissile excepted and non-fissile). (a) In addition to any other... non-fissile uranium hexafluoride must be offered for transportation as follows: (1) Before initial...

  3. Between Law and the Exception: The UN 1267 Ombudsperson as a Hybrid Model of Legal Expertise

    NARCIS (Netherlands)

    Sullivan, G.; de Goede, M.

    2013-01-01

    Security measures taken in the name of the ‘war on terror’ have frequently been understood to operate through a domain of exception, defined as an extra-legal space of intervention where normal rules of juridical protection and due process are suspended. Yet whilst most analyses of the exception are

  4. 13 CFR 107.1000 - Licensees without Leverage-exceptions to the regulations.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Licensees without Leverage-exceptions to the regulations. 107.1000 Section 107.1000 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Non-leveraged Licensees-Exceptions to Regulations § 107.1000...

  5. 76 FR 67363 - Extending Religious and Family Member FICA and FUTA Exceptions to Disregarded Entities

    Science.gov (United States)

    2011-11-01

    ... unless the requisite family relationship exists between the employee and each of the partners comprising... the exceptions from employment that apply because of the existence of a family relationship between...(c). The inability of these entities to benefit from the exceptions for family employees and members...

  6. Investigating the Factors of Resiliency among Exceptional Youth Living in Rural Underserved Communities

    Science.gov (United States)

    Curtin, Kevin A.; Schweitzer, Ashley; Tuxbury, Kristen; D'Aoust, Janelle A.

    2016-01-01

    Resilience is an important social justice concept that has important implications for educators working with exceptional youth in rural underserved communities who may suffer from the consequences associated with economic hardships. This multi-school qualitative study examined resilience among exceptional youth living in rural poverty through the…

  7. 22 CFR 210.515 - Are there any provisions for exceptions to those actions?

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Are there any provisions for exceptions to those actions? 210.515 Section 210.515 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT... or designee determines that such a waiver would be in the public interest. This exception authority...

  8. Public Policy Exceptions in European Private Law : A New Research Project

    NARCIS (Netherlands)

    Colombi Ciacchi, Aurelia

    2014-01-01

    Public policy exceptions arguably exist in all fields of private and commerciallaw, not only in private international law but also in substantive law. In substantive private law, the term 'public policy exception' could be used to indicate general illegality rules that make an act of private

  9. 46 CFR 111.103-1 - Power ventilation systems except machinery space ventilation systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Power ventilation systems except machinery space ventilation systems. 111.103-1 Section 111.103-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... Power ventilation systems except machinery space ventilation systems. Each power ventilation system must...

  10. 36 CFR 51.42 - Are there exceptions to this compensable interest prohibition?

    Science.gov (United States)

    2010-07-01

    ... compensable interest prohibition? 51.42 Section 51.42 Parks, Forests, and Public Property NATIONAL PARK... exceptions to this compensable interest prohibition? Two exceptions to this compensable interest prohibition... owned in fee simple by a concessioner or owned in fee simple by a concessioner's predecessor before the...

  11. 16 CFR Appendix G5 to Part 305 - Boilers-Gas (Except Steam)

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Boilers-Gas (Except Steam) G5 Appendix G5 to Part 305 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULE... Appendix G5 to Part 305—Boilers—Gas (Except Steam) Manufacturer's rated heating capacities (Btu's/hr...

  12. 16 CFR 313.15 - Other exceptions to notice and opt out requirements.

    Science.gov (United States)

    2010-01-01

    ... consumer. (2) A consumer may revoke consent by subsequently exercising the right to opt out of future... ACTS OF CONGRESS PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 313.15 Other exceptions to... at the direction of the consumer, provided that the consumer has not revoked the consent or direction...

  13. 12 CFR 573.15 - Other exceptions to notice and opt out requirements.

    Science.gov (United States)

    2010-01-01

    ... consumer. (2) A consumer may revoke consent by subsequently exercising the right to opt out of future... PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 573.15 Other exceptions to notice and opt out... consumer, provided that the consumer has not revoked the consent or direction; (2)(i) To protect the...

  14. 12 CFR 332.15 - Other exceptions to notice and opt out requirements.

    Science.gov (United States)

    2010-01-01

    ... insurance to the consumer. (2) A consumer may revoke consent by subsequently exercising the right to opt out... STATEMENTS OF GENERAL POLICY PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 332.15 Other exceptions... consent or at the direction of the consumer, provided that the consumer has not revoked the consent or...

  15. 12 CFR 716.15 - Other exceptions to notice and opt out requirements.

    Science.gov (United States)

    2010-01-01

    ... insurance to the consumer. (2) A consumer may revoke consent by subsequently exercising the right to opt out... AFFECTING CREDIT UNIONS PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 716.15 Other exceptions to... notice to consumers in § 716.4(a)(2), the opt out in §§ 716.7 and 716.10 and service providers and joint...

  16. 39 CFR 959.24 - Exceptions to initial decision or tentative decision.

    Science.gov (United States)

    2010-07-01

    ... failed to file an answer, may appeal to the Judicial Officer by filing exceptions in a brief on appeal... in a proceeding presided over by the Judicial Officer, except one who has failed to file an answer... matter in the order indicated: (1) A subject index of the matters presented, with page references; a...

  17. 7 CFR 4290.835 - Exceptions to minimum term of Financing.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Exceptions to minimum term of Financing. 4290.835... (âRBICâ) PROGRAM Financing of Enterprises by RBICs Structuring Rbic Financing of Eligible Enterprises-Types of Financings § 4290.835 Exceptions to minimum term of Financing. You may make a Financing with a...

  18. Future School Counselors' Perceptions of Twice-Exceptionality: An Exploratory Study

    Science.gov (United States)

    Leggett, Debra; Shea, Irene; Leggett, Joanna

    2011-01-01

    An exploratory survey was given to school counselors-in-training to gather preliminary information about their perceptions regarding students with twice-exceptionalities, their professional roles concerning service provision, and the roles of other helpers in assisting twice-exceptional students in the school setting. Thirty-seven participants…

  19. 38 CFR 14.504 - Domestic relations questions, authority and exceptions.

    Science.gov (United States)

    2010-07-01

    ... questions, authority and exceptions. 14.504 Section 14.504 Pensions, Bonuses, and Veterans' Relief... relations questions, authority and exceptions. (a) Regional Counsels have the same authority with respect to... reasonably available facilities, and forward two copies thereof directly to the General Counsel for review...

  20. 12 CFR 717.21 - Affiliate marketing opt-out and exceptions.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Affiliate marketing opt-out and exceptions. 717.21 Section 717.21 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.21 Affiliate marketing opt-out and exceptions. (a...

  1. 5 CFR 316.702 - Excepted positions brought into the competitive service.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Excepted positions brought into the competitive service. 316.702 Section 316.702 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL... provisions of § 316.402. (d) An employee who was serving under an excepted appointment with a definite time...

  2. 46 CFR 53.01-10 - Service restrictions and exceptions (replaces HG-101).

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Service restrictions and exceptions (replaces HG-101... ENGINEERING HEATING BOILERS General Requirements § 53.01-10 Service restrictions and exceptions (replaces HG... lieu of the requirements in HG-101 of section IV of the ASME Boiler and Pressure Vessel Code...

  3. 17 CFR 248.13 - Exception to opt out requirements for service providers and joint marketing.

    Science.gov (United States)

    2010-04-01

    ... include marketing of your own products or services or marketing of financial products or services offered... requirements for service providers and joint marketing. 248.13 Section 248.13 Commodity and Securities... Consumer Financial Information and Safeguarding Personal Information Exceptions § 248.13 Exception to opt...

  4. 12 CFR 716.13 - Exception to opt out requirements for service providers and joint marketing.

    Science.gov (United States)

    2010-01-01

    ... section may include marketing of your own products or services or marketing of financial products or... providers and joint marketing. 716.13 Section 716.13 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS PRIVACY OF CONSUMER FINANCIAL INFORMATION Exceptions § 716.13 Exception to...

  5. Unveiling Exception Handling Bug Hazards in Android Based on GitHub and Google Code Issues

    NARCIS (Netherlands)

    Coelho, R.; Almeida, L.; Gousios, G.; Van Deursen, A.

    2015-01-01

    This paper reports on a study mining the exception stack traces included in 159,048 issues reported on Android projects hosted in GitHub (482 projects) and Google Code (157 projects). The goal of this study is to investigate whether stack trace information can reveal bug hazards related to exception

  6. The Advocacy Experiences of Parents of Elementary Age, Twice-Exceptional Children

    Science.gov (United States)

    Besnoy, Kevin D.; Swoszowski, Nicole C.; Newman, Jane L.; Floyd, Amanda; Jones, Parrish; Byrne, Caitlin

    2015-01-01

    For many parents, successfully advocating for their twice-exceptional child can be intimidating and overwhelming. Using grounded theory, we conducted a study with parents (n = 8) of elementary age, twice-exceptional children to learn about their advocacy experiences. Findings revealed that parents simultaneously advocated for their child's…

  7. Why HIV/AIDS should be treated as exceptional: arguments from ...

    African Journals Online (AJOL)

    African Journal of AIDS Research ... The idea that HIV and AIDS gets too much attention and funding emerged in 2008 with a call to end 'AIDS exceptionalism.' This article outlines a short history of AIDS exceptionalism — the idea that HIV and AIDS require a response above and beyond 'normal' health interventions and is ...

  8. 77 FR 17456 - Buy American Exception Under the American Recovery and Reinvestment Act of 2009

    Science.gov (United States)

    2012-03-26

    ...-2138-01] Buy American Exception Under the American Recovery and Reinvestment Act of 2009 AGENCY... exception to the Buy American Provisions of the American Recovery and Reinvestment Act of 2009 (ARRA or... future years on electricity. The contract specifications required that all exterior photovoltaic...

  9. 16 CFR 680.21 - Affiliate marketing opt-out and exceptions.

    Science.gov (United States)

    2010-01-01

    ... marketing purposes to a consumer with whom you have a pre-existing business relationship; (2) To facilitate... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Affiliate marketing opt-out and exceptions... AFFILIATE MARKETING § 680.21 Affiliate marketing opt-out and exceptions. (a) Initial notice and opt-out...

  10. 12 CFR 571.21 - Affiliate marketing opt-out and exceptions.

    Science.gov (United States)

    2010-01-01

    ... solicitation for marketing purposes to a consumer with whom you have a pre-existing business relationship; (2... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Affiliate marketing opt-out and exceptions. 571... CREDIT REPORTING Affiliate Marketing § 571.21 Affiliate marketing opt-out and exceptions. (a) Initial...

  11. The heritability of aptitude and exceptional talent across different domains in adolescents and young adults

    NARCIS (Netherlands)

    Vinkhuyzen, A.A.E.; van der Sluis, S.; Posthuma, D.; Boomsma, D.I.

    2009-01-01

    The origin of individual differences in aptitude, defined as a domain-specific skill within the normal ability range, and talent, defined as a domain specific skill of exceptional quality, is under debate. The nature of the variation in aptitudes and exceptional talents across different domains was

  12. Practical exercises in diversity

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    On 4 July, the Bulletin took part in an interactive workshop in the framework of the CERN Diversity programme. And it was time very well spent. Read on…   Discussion on the theme "unconscious bias". The participants begin to gather in the Pump Room (Building 2016) around 1.30 p.m. With name-tags stuck to our chests, we take our places at Table 7, which we now realise we selected for ourselves at random. Some people have already arrived, and after some tentative, courteous introductions, the atmosphere at the “sevens table” begins to warm up. A few minutes later, the workshop begins. Alan Richter, CEO of HR consultancy firm QED Consulting is the Master of Ceremonies. First exercise, “the circle”, or how to prove that diversity starts right under your nose. Skiers to the left, non-skiers to the right. The overwhelming majority are skiers. How do the non-skiers feel about finding themselves in the minority? Uncomfortable? Exc...

  13. Tapping into yeast diversity.

    Science.gov (United States)

    Fay, Justin C

    2012-11-01

    Domesticated organisms demonstrate our capacity to influence wild species but also provide us with the opportunity to understand rapid evolution in the context of substantially altered environments and novel selective pressures. Recent advances in genetics and genomics have brought unprecedented insights into the domestication of many organisms and have opened new avenues for further improvements to be made. Yet, our ability to engineer biological systems is not without limits; genetic manipulation is often quite difficult. The budding yeast, Saccharomyces cerevisiae, is not only one of the most powerful model organisms, but is also the premier producer of fermented foods and beverages around the globe. As a model system, it entertains a hefty workforce dedicated to deciphering its genome and the function it encodes at a rich mechanistic level. As a producer, it is used to make leavened bread, and dozens of different alcoholic beverages, such as beer and wine. Yet, applying the awesome power of yeast genetics to understanding its origins and evolution requires some knowledge of its wild ancestors and the environments from which they were derived. A number of surprisingly diverse lineages of S. cerevisiae from both primeval and secondary forests in China have been discovered by Wang and his colleagues. These lineages substantially expand our knowledge of wild yeast diversity and will be a boon to elucidating the ecology, evolution and domestication of this academic and industrial workhorse.

  14. Extraordinary Genetic Diversity in a Wood Decay Mushroom.

    Science.gov (United States)

    Baranova, Maria A; Logacheva, Maria D; Penin, Aleksey A; Seplyarskiy, Vladimir B; Safonova, Yana Y; Naumenko, Sergey A; Klepikova, Anna V; Gerasimov, Evgeny S; Bazykin, Georgii A; James, Timothy Y; Kondrashov, Alexey S

    2015-10-01

    Populations of different species vary in the amounts of genetic diversity they possess. Nucleotide diversity π, the fraction of nucleotides that are different between two randomly chosen genotypes, has been known to range in eukaryotes between 0.0001 in Lynx lynx and 0.16 in Caenorhabditis brenneri. Here, we report the results of a comparative analysis of 24 haploid genotypes (12 from the United States and 12 from European Russia) of a split-gill fungus Schizophyllum commune. The diversity at synonymous sites is 0.20 in the American population of S. commune and 0.13 in the Russian population. This exceptionally high level of nucleotide diversity also leads to extreme amino acid diversity of protein-coding genes. Using whole-genome resequencing of 2 parental and 17 offspring haploid genotypes, we estimate that the mutation rate in S. commune is high, at 2.0 × 10(-8) (95% CI: 1.1 × 10(-8) to 4.1 × 10(-8)) per nucleotide per generation. Therefore, the high diversity of S. commune is primarily determined by its elevated mutation rate, although high effective population size likely also plays a role. Small genome size, ease of cultivation and completion of the life cycle in the laboratory, free-living haploid life stages and exceptionally high variability of S. commune make it a promising model organism for population, quantitative, and evolutionary genetics. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  15. Healthcare leadership's diversity paradox.

    Science.gov (United States)

    Silver, Reginald

    2017-02-06

    Purpose The purpose of this research study was to obtain healthcare executives' perspectives on diversity in executive healthcare leadership. The study focused on identifying perspectives about diversity and its potential impact on the access of healthcare services by people of color. The study also identified perspectives about factors that influence the attainment of executive healthcare roles by people of color. Design/methodology/approach A convenience sample of healthcare executives was obtained. The executives identified themselves as belonging to one of two subgroups, White healthcare executives or executives of color. Participants were interviewed telephonically in a semi-structured format. The interviews were transcribed and entered into a qualitative software application. The data were codified and important themes were identified. Findings The majority of the study participants perceive that diversity of the executive healthcare leadership team is important. There were differences in perspective among the subgroups as it relates to solutions to improve access to healthcare by people of color. There were also differences in perspective among the subgroups, as it relates to explaining the underrepresentation of people of color in executive healthcare leadership roles. Research limitations/implications This research effort benefited from the subject matter expertise of 24 healthcare executives from two states. Expansion of the number of survey participants and broadening the geographical spread of where participants were located may have yielded more convergence and/or more divergence in perspectives about key topics. Practical implications The findings from this research study serve to add to the existing body of literature on diversity in executive healthcare leadership. The findings expand on the importance of key elements in contemporary literature such as diversity, cultural competency and perspectives about the need for representation of people of

  16. Exceptional structures in mathematics and physics and the role of the octonions

    International Nuclear Information System (INIS)

    Toppan, Francesco

    2003-12-01

    There is a growing interest in the logical possibility that exceptional mathematical structures (exceptional Lie and super Lie algebras, the exceptional Jordan algebra, etc.) could be linked to an ultimate 'exceptional' formulation for a Theory Of Everything (TOE). The maximal division algebra of the octonions can be held as the mathematical responsible for the existence of the exceptional structures mentioned above. In this context it is quite motivating to systematically investigate the properties of octonionic spinors and the octonionic realizations of supersymmetry. In particular the M-algebra can be consistently defined for two structures only, a real structure, leading to the standard M-algebra, and an octonionic structure. The octonionic version of the M-algebra admits striking properties induced by octonionic p-forms identities. (author)

  17. Exceptional structures in mathematics and physics and the role of the octonions

    Energy Technology Data Exchange (ETDEWEB)

    Toppan, Francesco

    2003-12-15

    There is a growing interest in the logical possibility that exceptional mathematical structures (exceptional Lie and super Lie algebras, the exceptional Jordan algebra, etc.) could be linked to an ultimate 'exceptional' formulation for a Theory Of Everything (TOE). The maximal division algebra of the octonions can be held as the mathematical responsible for the existence of the exceptional structures mentioned above. In this context it is quite motivating to systematically investigate the properties of octonionic spinors and the octonionic realizations of supersymmetry. In particular the M-algebra can be consistently defined for two structures only, a real structure, leading to the standard M-algebra, and an octonionic structure. The octonionic version of the M-algebra admits striking properties induced by octonionic p-forms identities. (author)

  18. Three Justifications for Effectively Teaching Exceptional Babies to Third Grade with Respect to Their Characteristics, an Effective Curricula, and an Exceptional-Research Data Base

    Science.gov (United States)

    Jaramillo, James Anthony Montrose

    2013-01-01

    Both Pre-K and K-3rd grade exceptional or talented children/students not only want but need more of an "accommodative" ambiance where their senses are given novel multiple-intelligences data so that they can continue to intellectually grow with respect to Piaget, Erickson, and Vygotsky's developmental schemes. Thus, to do this requires us to…

  19. Trust in Diverse Teams

    DEFF Research Database (Denmark)

    Clausen, Lisbeth

    , maintaining team cohesiveness in multicultural teams to collaborate effectively presents a number of challenges. The present study employs the concept of trust to explore influences on team collaboration in high performing teams. The study is based on observation of teams in seven multinational corporations...... and interviews with managers from the US, Europe, China and Japan. The study presents a conceptual framework - a ‘trust buffer’ – which enables analysis and exemplification of the dynamics and challenges of teams as drivers of change. Each team has strategically important tasks, unique capacities and deal...... with change in particular ways: Each team is analyzed in relation to its global (HQ) mandate, local (national) stakeholders and organizational context. It is found that communication energy, resources and team mandate underscore the sense of trust in high performing teams. Diversity is understood...

  20. Prices and species diversity

    DEFF Research Database (Denmark)

    Sauer, Johannes

    of biodiversity and the appropriate incorporation in stochastic fron-tier models to achieve more realistic measures of production efficiency. We use the empirical example of tobacco production drawing from as well as affecting species diversity in the surrounding forests. We apply a shadow profit distance......In recent decades a significant amount of literature has been produced concerned with establishing a link between production efficiency and environmental efficiency with respect to quantitative modelling. This has been mainly addressed by focusing on the incorporation of undesirable outputs...... or the incorporation of environmentally det-rimental inputs. However, while the debate with respect to linear programming based DEA modelling is already at an advanced stage the corresponding one with respect to stochastic frontier modelling still needs considerable efforts. This contribution fo-cuses on the case...

  1. Tourism and diversity

    Directory of Open Access Journals (Sweden)

    Zsuzsanna Bacsi

    2017-10-01

    Full Text Available Cultural attractions are often linked to unique features of the host population, and are often related to a national minority or a segment of the population that preserved their traditions. Ethnically or religiously varied countries may often have such unique attractions, that seem exotic and appealing to tourists. Multiculturality is often an attraction for tourism, offering generally an authentic experience for visitors of different backgrounds. Besides, an ethnically or linguistically varied population can also provide a linguisticaly more skilful labour force, that is more sensitive to the needs of visitors coming from different cultures, and thus create a more comfortable environment for them. The issue of multicultural societies has recently become a sensitive issue, due to global mass migration. There is a belief that ethnic or cultural fractionalisation would necessarily bring about difficulties of understanding and cooperation, leading to lower economic performance, less stable economic and social processes and, ultimately a slowdown of economic output. The resulting conflicts, difficulties may frighten away tourists and lead to the vulnerability of the tourism sector in very heterogeneous countries. On the other hand, ethnic fractionalisation and the resulting cultural diversity can be welcome as valuable resources as the varied pool of knowledge, traditions, skills, customs, that can enhance innovative ideas and creativity. In the present paper evidence is looked for the relationship between ethnic, linguistic and religious diversity and tourism performance in a cross-country statistical analysis of 155 countries of the world. Statistical analysis of 155 countries show, that although there is a tendency of lower tourism performance with greated fractionalisation of the society, the most popular and successful tourism destinations are often multicultural and multiethnic societies.

  2. Environmental barcoding reveals massive dinoflagellate diversity in marine environments.

    Directory of Open Access Journals (Sweden)

    Rowena F Stern

    2010-11-01

    Full Text Available Dinoflagellates are an ecologically important group of protists with important functions as primary producers, coral symbionts and in toxic red tides. Although widely studied, the natural diversity of dinoflagellates is not well known. DNA barcoding has been utilized successfully for many protist groups. We used this approach to systematically sample known "species", as a reference to measure the natural diversity in three marine environments.In this study, we assembled a large cytochrome c oxidase 1 (COI barcode database from 8 public algal culture collections plus 3 private collections worldwide resulting in 336 individual barcodes linked to specific cultures. We demonstrate that COI can identify to the species level in 15 dinoflagellate genera, generally in agreement with existing species names. Exceptions were found in species belonging to genera that were generally already known to be taxonomically challenging, such as Alexandrium or Symbiodinium. Using this barcode database as a baseline for cultured dinoflagellate diversity, we investigated the natural diversity in three diverse marine environments (Northeast Pacific, Northwest Atlantic, and Caribbean, including an evaluation of single-cell barcoding to identify uncultivated groups. From all three environments, the great majority of barcodes were not represented by any known cultured dinoflagellate, and we also observed an explosion in the diversity of genera that previously contained a modest number of known species, belonging to Kareniaceae. In total, 91.5% of non-identical environmental barcodes represent distinct species, but only 51 out of 603 unique environmental barcodes could be linked to cultured species using a conservative cut-off based on distances between cultured species.COI barcoding was successful in identifying species from 70% of cultured genera. When applied to environmental samples, it revealed a massive amount of natural diversity in dinoflagellates. This highlights

  3. Center variation in the use of nonstandardized model for end-stage liver disease exception points.

    Science.gov (United States)

    Goldberg, David S; Makar, George; Bittermann, Therese; French, Benjamin

    2013-12-01

    The Model for End-Stage Liver Disease (MELD) score is an imperfect prognosticator of waitlist dropout, so transplant centers may apply for exception points to increase a waitlist candidate's priority on the waitlist. Exception applications are categorized as recognized exceptional diagnoses (REDs; eg, hepatocellular carcinoma) and non-REDs (eg, cholangitis). Although prior work has demonstrated regional variation in the use of exceptions, no work has examined the between-center variability. We analyzed all new waitlist candidates from February 27, 2002 to June 3, 2011 to explore variations in the use of non-REDs, for which no strict exception criteria exist. There were 58,641 new waitlist candidates, and 4356 (7.4%) applied for a non-RED exception. The number of applications increased steadily over time, as did the approval rates for such applications: from variation to ensure the appropriate and equitable use of non-RED exceptions. © 2013 American Association for the Study of Liver Diseases.

  4. Fingerprints of exceptional points in the survival probability of resonances in atomic spectra

    International Nuclear Information System (INIS)

    Cartarius, Holger; Moiseyev, Nimrod

    2011-01-01

    The unique time signature of the survival probability exactly at the exceptional point parameters is studied here for the hydrogen atom in strong static magnetic and electric fields. We show that indeed the survival probability S(t)=| | 2 decays exactly as |1-at| 2 e -Γ EP t/(ℎ/2π) , where Γ EP is associated with the decay rate at the exceptional point and a is a complex constant depending solely on the initial wave packet that populates exclusively the two almost degenerate states of the non-Hermitian Hamiltonian. This may open the possibility for a first experimental detection of exceptional points in a quantum system.

  5. Fingerprints of exceptional points in the survival probability of resonances in atomic spectra

    Science.gov (United States)

    Cartarius, Holger; Moiseyev, Nimrod

    2011-07-01

    The unique time signature of the survival probability exactly at the exceptional point parameters is studied here for the hydrogen atom in strong static magnetic and electric fields. We show that indeed the survival probability S(t)=||2 decays exactly as |1-at|2e-ΓEPt/ℏ, where ΓEP is associated with the decay rate at the exceptional point and a is a complex constant depending solely on the initial wave packet that populates exclusively the two almost degenerate states of the non-Hermitian Hamiltonian. This may open the possibility for a first experimental detection of exceptional points in a quantum system.

  6. Power-law scaling of extreme dynamics near higher-order exceptional points

    Science.gov (United States)

    Zhong, Q.; Christodoulides, D. N.; Khajavikhan, M.; Makris, K. G.; El-Ganainy, R.

    2018-02-01

    We investigate the extreme dynamics of non-Hermitian systems near higher-order exceptional points in photonic networks constructed using the bosonic algebra method. We show that strong power oscillations for certain initial conditions can occur as a result of the peculiar eigenspace geometry and its dimensionality collapse near these singularities. By using complementary numerical and analytical approaches, we show that, in the parity-time (PT ) phase near exceptional points, the logarithm of the maximum optical power amplification scales linearly with the order of the exceptional point. We focus in our discussion on photonic systems, but we note that our results apply to other physical systems as well.

  7. Pair of Exceptional Points in a Microdisk Cavity under an Extremely Weak Deformation

    Science.gov (United States)

    Yi, Chang-Hwan; Kullig, Julius; Wiersig, Jan

    2018-03-01

    One of the interesting features of open quantum and wave systems is the non-Hermitian degeneracy called an exceptional point, where not only energy levels but also the corresponding eigenstates coalesce. We demonstrate that such a degeneracy can appear in optical microdisk cavities by deforming the boundary extremely weakly. This surprising finding is explained by a semiclassical theory of dynamical tunneling. It is shown that the exceptional points come in nearly degenerated pairs, originating from the different symmetry classes of modes. A spatially local chirality of modes at the exceptional point is related to vortex structures of the Poynting vector.

  8. From Diversity Management to Diversimilation

    DEFF Research Database (Denmark)

    Holck, Lotte; Muhr, Sara Louise

    “Diversimilation” as a corporate response to diversity By PhD fellow Lotte Holck, Copenhagen Business School (IOA) Abstract Across the North Atlantic organizations struggle to harvest the perceived ’ fruits’ of diversity of enhanced organizational learning and requisite variety enriching task...... performance in response to globalized markets and customers – but by means of different approaches to organizing diversity (Klarsfeld 2012, Embrick 2011, Banting 2010, Holvino & Kamp 2009, Matten & Moon 2008, Risberg & Søderberg 2008, Campbell 2007, Boxenbaum 2007). The argument of this paper...... is that this is partly due to the history of diversity and maturity of the diversity agenda, where especially the US confrontation with and acknowledgement of a colonial past has made way for a more "advanced" approach valuing diversity, while in a Danish context - through distancing itself from having an explicit...

  9. Ethnic Diversity and Social Trust

    DEFF Research Database (Denmark)

    Dinesen, Peter Thisted; Sønderskov, Kim Mannemar

    2015-01-01

    We argue that residential exposure to ethnic diversity reduces social trust. Previous within-country analyses of the relationship between contextual ethnic diversity and trust have been conducted at higher levels of aggregation, thus ignoring substantial variation in actual exposure to ethnic......, whereas the effect vanishes in larger contextual units. This supports the conjecture that interethnic exposure underlies the negative relationship between ethnic diversity in residential contexts and social trust....... diversity. In contrast, we analyze how ethnic diversity of the immediate micro-context—where interethnic exposure is inevitable—affects trust. We do this using Danish survey data linked with register-based data, which enables us to obtain precise measures of the ethnic diversity of each individual...

  10. Cultural Diversity and Team Performance

    DEFF Research Database (Denmark)

    Hoogendoorn, Sander; Van Praag, Mirjam

    One of the most salient and relevant dimensions of team heterogeneity is cultural background. We measure the impact of cultural diversity on the performance of business teams using a field experiment. Companies are set up by teams of undergraduate students in business studies in realistic though...... similar circumstances. We vary the cultural composition of otherwise randomly composed teams in a multi-cultural student population. Our data indicate that a moderate level of cultural diversity has no effect on team performance in terms of business outcomes (sales, profits and profits per share). However......, if at least the majority of team members is culturally diverse then more cultural diversity seems to affect the performance of teams positively. Our data suggest that this might be related to the more diverse pool of relevant knowledge facilitating (mutual) learning within culturally diverse teams....

  11. Diversity in the dermatology workforce.

    Science.gov (United States)

    Hinojosa, Jorge A; Pandya, Amit G

    2016-12-01

    The United States is becoming increasingly diverse, and minorities are projected to represent the majority of our population in the near future. Unfortunately, health disparities still exist for these groups, and inequalities have also become evident in the field of dermatology. There is currently a lack of diversity within the dermatology workforce. Potential solutions to these health care disparities include increasing cultural competence for all physicians and improving diversity in the dermatology workforce. ©2016 Frontline Medical Communications.

  12. Leadership Competencies for Managing Diversity

    OpenAIRE

    Jan Visagie; Herman Linde; Werner Havenga

    2011-01-01

    The new understanding of diversity involves more than increasing the number of different identity groups on the payroll. An important proposal is that the experience of diversity in an organisation results from pervasive styles of management. This article dealt with the specific paradigms of diversitymanagement and leadership style theory used to address the research problem in the empirical study, namely ‘Is diversity management experience related to leadership styles or competencies?’ The m...

  13. Diversity Management in the Workplace

    Directory of Open Access Journals (Sweden)

    Hana Urbancová

    2016-01-01

    Full Text Available Diversity is a phenomenon which is increasingly manifesting itself in the globalized society; therefore, it is observable in various areas of human activity, and thus also in the labour market and work teams. Age, sex, ethnicity and nationality, creed or disabilities are among the parameters of diversity. The aim of the article is to identify and evaluate the implementation of Diversity Management in workplaces, whilst bearing in mind researched factors of diversity. The results were gained by conducting a primary survey by questionnaire in organizations (n = 315. The results showed that a total of 41.9% of selected organizations operating in the Czech Republic implement Diversity Management. The largest part of organizations operate in the tertiary sector (69.7%. The survey results show the situation concerning Diversity Management in the selected organizations and support the oppinion that Diversity Management is a current global matter and its concerns all organizations. The research parameters influenced the application of Diversity Management in organizations (Cramer’s V is from 0.176 to 0.430. One of the recommendations for organizations is that they devote more attention to this phenomenon, as qualified human resources is on the decline and adequate attention will once again need to be devoted to groups of potential workers who have hitherto been overlooked. Diversity Management represents a new opportunity for organizations to build the employer’s good brand and attract knowledge workers.

  14. Diversity-Guided Evolutionary Algorithms

    DEFF Research Database (Denmark)

    Ursem, Rasmus Kjær

    2002-01-01

    Population diversity is undoubtably a key issue in the performance of evolutionary algorithms. A common hypothesis is that high diversity is important to avoid premature convergence and to escape local optima. Various diversity measures have been used to analyze algorithms, but so far few...... algorithms have used a measure to guide the search. The diversity-guided evolutionary algorithm (DGEA) uses the wellknown distance-to-average-point measure to alternate between phases of exploration (mutation) and phases of exploitation (recombination and selection). The DGEA showed remarkable results...

  15. WATER DIVERSION MODEL

    International Nuclear Information System (INIS)

    J.B. Case

    1999-01-01

    The distribution of seepage in the proposed repository will be highly variable due in part to variations in the spatial distribution of percolations. The performance of the drip shield and the backfill system may divert the water flux around the waste packages to the invert. Diversion will occur along the drift surface, within the backfill, at the drip shield, and at the Waste Package (WP) surface, even after the drip shield and WP have been breached by corrosion. The purpose and objective of this Analysis and Modeling Report (AMR) are to develop a conceptual model and constitutive properties for bounding the volume and rate of seepage water that flows around the drip shield (CRWMS MandO 1999c). This analysis model is to be compatible with the selected repository conceptual design (Wilkins and Heath, 1999) and will be used to evaluate the performance of the Engineered Barrier System (EBS), and to provide input to the EBS Water Distribution and Removal Model. This model supports the Engineered Barrier System (EBS) postclosure performance assessment for the Site Recommendation (SR). This document characterizes the hydrological constitutive properties of the backfill and invert materials (Section 6.2) and a third material that represents a mixture of the two. These include the Overton Sand which is selected as a backfill (Section 5.2), crushed tuff which is selected as the invert (Section 5.1), and a combined material (Sections 5.9 and 5.10) which has retention and hydraulic conductivity properties intermediate to the selected materials for the backfill and the invert. The properties include the grain size distribution, the dry bulk density and porosity, the moisture retention, the intrinsic permeability, the relative permeability, and the material thermal properties. The van Genuchten relationships with curve fit parameters are used to define the basic retention relationship of moisture potential to volumetric moisture content, and the basic relationship of

  16. WATER DIVERSION MODEL

    Energy Technology Data Exchange (ETDEWEB)

    J.B. Case

    1999-12-21

    The distribution of seepage in the proposed repository will be highly variable due in part to variations in the spatial distribution of percolations. The performance of the drip shield and the backfill system may divert the water flux around the waste packages to the invert. Diversion will occur along the drift surface, within the backfill, at the drip shield, and at the Waste Package (WP) surface, even after the drip shield and WP have been breached by corrosion. The purpose and objective of this Analysis and Modeling Report (AMR) are to develop a conceptual model and constitutive properties for bounding the volume and rate of seepage water that flows around the drip shield (CRWMS M&O 1999c). This analysis model is to be compatible with the selected repository conceptual design (Wilkins and Heath, 1999) and will be used to evaluate the performance of the Engineered Barrier System (EBS), and to provide input to the EBS Water Distribution and Removal Model. This model supports the Engineered Barrier System (EBS) postclosure performance assessment for the Site Recommendation (SR). This document characterizes the hydrological constitutive properties of the backfill and invert materials (Section 6.2) and a third material that represents a mixture of the two. These include the Overton Sand which is selected as a backfill (Section 5.2), crushed tuff which is selected as the invert (Section 5.1), and a combined material (Sections 5.9 and 5.10) which has retention and hydraulic conductivity properties intermediate to the selected materials for the backfill and the invert. The properties include the grain size distribution, the dry bulk density and porosity, the moisture retention, the intrinsic permeability, the relative permeability, and the material thermal properties. The van Genuchten relationships with curve fit parameters are used to define the basic retention relationship of moisture potential to volumetric moisture content, and the basic relationship of unsaturated

  17. [Effect of Debriefing Based on the Clinical Judgment Model on Simulation Based Learning Outcomes of End-of-Life Care for Nursing Students: A Non-Randomized Controlled Trial].

    Science.gov (United States)

    Jeong, Kyung In; Choi, Ja Yun

    2017-12-01

    This study was conducted to identify effects of debriefing based on the clinical judgment model for nursing students on their knowledge, skill performance, clinical judgment, self-confidence and learner satisfaction during simulation based end-of-life care (ELC) education. Simulation based ELC education was developed in six steps as follows: selection of learning subjects and objects, development of learning tools, a trial run of simulation-based education, students' skill training, and evaluators' training. Forty-eight senior nursing students (25 in the experimental group and 23 in the control group) participated in the simulation-based ELC education using a high-fidelity simulator. Debriefing based on the clinical judgment was compared with the usual debriefing. ANCOVA showed that there were differences in knowledge (F=4.81, p=.034), skill performance (F=68.33, psatisfaction (t=-0.38, p=.704) between the experimental and control groups. This study found that debriefing based on the clinical judgement model is effective for supporting nursing students for reflecting on clinical judgment and improving their diverse competencies in complex clinical settings such as ELC. © 2017 Korean Society of Nursing Science

  18. The Exceptional Lie symmetry groups hierarchy and the expected number of Higgs bosons

    International Nuclear Information System (INIS)

    El Naschie, M.S.

    2008-01-01

    New insights into the structure of various exceptional Lie symmetry groups hierarchies are utilized to shed light on various problems pertinent to the standard model of high energy physics and the Higgs

  19. Military Personnel: Medical, Family Support, and Educational Services Are Available for Exceptional Family Members

    National Research Council Canada - National Science Library

    Crosse, Marcia

    2007-01-01

    The Department of Defense's (DOD) Exceptional Family Member Program (EFMP) is a mandatory enrollment program for active duty servicemembers who have family members with special medical needs. The Ronald W...

  20. SUBSTANTIAL EXCEPTIONS AND (DELIMITATIONS OF THE POWERS OF THE JUDGES ON CIVIL PROCEDURAL LAW

    Directory of Open Access Journals (Sweden)

    Igor Raatz

    2017-08-01

    Full Text Available This essay aims to unveil the role of the substantial exceptions on delimiting the powers of the judges on civil procedural law, especially regarding the ex officio judicial activity. This way, under a phenomenological method and based on a vision of guarantee of rights on procedural law, the article offers a brief explanation of the question concerning the content of the object under litigation and its role of (delimiting the powers of the judges. The work hypothesis is the addition of the substantial exceptions among the content of the object under litigation, along with the claim itself and the cause of action. The results lie on the premise that, by the substantial exceptions, the defendant extends the object under litigation – which is formed dynamically on civil procedure. The conclusion points towards the idea that the substantial exceptions act in a way of limiting the ex officio judicial activity on civil procedural law