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Sample records for evolving giant dermatofibroma

  1. Giant Ulcerative Dermatofibroma

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    Turgut Karlidag

    2013-01-01

    Full Text Available Dermatofibroma is a slowly growing common benign cutaneous tumor characterized by hard papules and nodules. The rarely seen erosions and ulcerations may cause difficulties in the diagnosis. Dermatofibrosarcoma protuberans, which is clinically and histopathologically of malignant character, displays difficulties in the diagnosis since it has similarities with basal cell carcinoma, epidermoid carcinoma, and sarcomas. Head and neck involvement is very rare. In this study, a giant dermatofibroma case, which is histopathologically, ulcerative dermatofibroma, the biggest lesion of the head and neck region and seen rarely in the literature that has characteristics similar to dermatofibrosarcoma protuberans, has been presented.

  2. Ulcerated Giant Dermatofibroma following Routine Childhood Vaccination in a Young Boy

    Directory of Open Access Journals (Sweden)

    Michelle S.Y. Ng

    2016-08-01

    Full Text Available Introduction: The development of cutaneous neoplasms at immunization sites following vaccination is uncommon, and only few have been reported in the literature worldwide. We report an unusual case of an ulcerated giant dermatofibroma that developed as a chronic nonhealing plaque in the immunization scar of a young boy after vaccination. Case Report: A 13-month-old Chinese boy presented with an unusual skin reaction on the vaccination site at the right anterolateral thigh following a routine intramuscular injection of ‘5-in-1’ (diphtheria, tetanus, pertussis, polio and Haemophilus influenzae B vaccine at 4 months of age. The immunization site developed a slightly raised papule with a central punctum that progressively grew in size, ulcerated and showed occasional bleeding over a span of 9 months. On follow-up, the lesion showed a chronic granulomatous reaction with surrounding induration and a central scarring. The right inguinal lymph node was palpable. Ultrasound of the lesion showed only nonspecific focal skin thickening. An incisional skin biopsy with careful histopathological evaluation revealed microscopic features consistent with an ulcerated giant dermatofibroma. Conclusion: Neoplastic development in immunization scars following vaccination is a rare occurrence and, hence, makes this case a diagnostic challenge. A high index of suspicion is crucial in atypical presentations of a common skin lesion, as typified by this case. Careful history taking and clinicopathological correlation of clinical findings with gross and microscopic findings along with targeted immunohistological staining is often essential to aid early diagnosis.

  3. Hemosiderotic dermatofibroma*

    Science.gov (United States)

    Villarreal, Delky Johanna Villarreal; Luz, Aline Tanus; Buçard, Alice Mota; de Abreu, Luciana; Cuzzi, Tullia

    2017-01-01

    We report a rare clinical case of hemosiderotic dermatofibroma in a 36-year-old female patient. The main dermatoscopic finding was represented by homogeneous blue-gray pigmentation. The aim of this report is to demonstrate the rarity of the lesion and the dermatoscopic importance it assumes by sharing a blue-gray homogeneous pattern with other benign and malignant lesions. PMID:28225963

  4. Distinguishing a Rare Variant of Lipidized Dermatofibroma from Nonlipidized Dermatofibromas in a Patient with Hypothyroidism and Alopecia Areata

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    Abdulla Farah

    2017-06-01

    Full Text Available Introduction. Lipidized dermatofibromas represent rare and often underrecognized variants of dermatofibromas. Histologically, dermatofibromas are composed of fibroblast-like spindle cells, foam cells, giant cells, siderophages, lymphocytes, capillaries, collagen fibers, and hyaline dermal collagen fibers. Lipidized dermatofibromas are characterized by numerous foam cells, Touton giant cells, and hyalinized wiry collagen in the stroma. Case report. We present a case of a 31-year-old woman with a history of hypothyroidism and alopecia areata, presenting with an enlarging 8 mm, firm erythematous nodule on her upper-mid back. Biopsy examination showed a cellular proliferation of spindle cells with peripheral collagen trapping and cholesterol clefts with associated foam cells and sclerosis, staining weakly positive for Factor XIIIa and negative for CD34. The diagnosis of a benign lipidized dermatofibroma was rendered. Conclusion. Lipidized dermatofibromas are rare histologic variants of dermatofibromas, biologically indolent, and should be distinguished from other cutaneous foamy histiocytic lesions, particularly xanthomas, which may alter patient management.

  5. Multiple dermatofibromas: Dermoscopic patterns

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    Marianne Farache Camara

    2013-01-01

    Full Text Available Dermatofibromas are benign skin lesions that consist of pigmented papules or nodules. They produce the dimple sign when laterally squeezed and are usually found on the legs. These clinical features lead to the diagnosis in most cases. However, the differential diagnosis with other lesions, such as atypical nevi and melanoma can be difficult, and the dermoscopy may help the diagnosis. There are several dermoscopic patterns associated with dermatofibromas, the most common being a central white scar like patch with delicate pigment network at the periphery. This article describes the case of a patient who had eleven clinically similar dermatofibromas, with four distinct patterns when submitted to dermoscopic examination.

  6. Breast cancer, dermatofibromas and arsenic.

    Science.gov (United States)

    Dantzig, Paul I

    2009-01-01

    Dermatofibromas are common benign tumors in women, and breast cancer is the most common malignancy in women. The aim of this study is to determine if there is any relationship between the two conditions. Five patients with dermatofibromas and 10 control patients (two groups) had their skin biopsies measured for arsenic by inductively coupled mass spectrometry. Fifty randomly selected patients with breast cancer and 50 control patients were examined for the presence of dermatofibromas. The dermatofibromas were found to have an arsenic concentration of 0.171 micrograms/gram, compared with 0.06 and 0.07 micrograms/gram of the two control groups. Forty-three out of 50 patients with breast cancer had dermatofibromas and 32/50 patients with breast cancer had multiple dermatofibromas, compared to 10/50 control patients with dermatofibromas and only 1/50 with multiple dermatofibromas. Arsenic is important in the development of dermatofibromas and dermatofibromas represent a reservoir and important sign of chronic arsenic exposure. Dermatofibromas represent an important sign for women at risk for breast cancer, and arsenic may represent the cause of the majority of cases of breast cancer.

  7. Breast cancer, dermatofibromas and arsenic

    Directory of Open Access Journals (Sweden)

    Dantzig Paul

    2009-01-01

    Full Text Available Background: Dermatofibromas are common benign tumors in women, and breast cancer is the most common malignancy in women. The aim of this study is to determine if there is any relationship between the two conditions. Materials and Methods: Five patients with dermatofibromas and 10 control patients (two groups had their skin biopsies measured for arsenic by inductively coupled mass spectrometry. Fifty randomly selected patients with breast cancer and 50 control patients were examined for the presence of dermatofibromas. Results: The dermatofibromas were found to have an arsenic concentration of 0.171 micrograms/gram, compared with 0.06 and 0.07 micrograms/gram of the two control groups. Forty-three out of 50 patients with breast cancer had dermatofibromas and 32/50 patients with breast cancer had multiple dermatofibromas, compared to 10/50 control patients with dermatofibromas and only 1/50 with multiple dermatofibromas. Conclusions: Arsenic is important in the development of dermatofibromas and dermatofibromas represent a reservoir and important sign of chronic arsenic exposure. Dermatofibromas represent an important sign for women at risk for breast cancer, and arsenic may represent the cause of the majority of cases of breast cancer.

  8. BREAST CANCER, DERMATOFIBROMAS AND ARSENIC

    OpenAIRE

    Dantzig Paul

    2009-01-01

    Background: Dermatofibromas are common benign tumors in women, and breast cancer is the most common malignancy in women. The aim of this study is to determine if there is any relationship between the two conditions. Materials and Methods: Five patients with dermatofibromas and 10 control patients (two groups) had their skin biopsies measured for arsenic by inductively coupled mass spectrometry. Fifty randomly selected patients with breast cancer and 50 control patients were examined for...

  9. Dermatofibroma Arising within a Black Tattoo

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    Alejandro Lobato-Berezo

    2014-01-01

    Full Text Available Many complications have been reported over tattoos, some of which are tumours, such as dermatofibromas. It is important to establish a differential diagnosis because they can resemble other malignant lesions as dermatofibrosarcoma protuberans. We report the development of a dermatofibroma in a 21-year-old man with a tattoo painted two years ago.

  10. Clinical and histological patterns of dermatofibroma without gross skin surface change: A comparative study with conventional dermatofibroma

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    Woo Jin Lee

    2015-01-01

    Full Text Available Background : Dermatofibroma sometimes clinically presents as a nodular lesion without gross skin surface change. Clinicopathologic features of this variant of dermatofibroma have not been evaluated. Aims : To assess clinicopathologic features of dermatofibroma presenting as a subcutaneous nodule. Methods : This study reviewed the clinical and histological features of 42 cases of subcutaneous dermatofibromas and compared them with 95 cases of conventional dermatofibroma. Results : Dermatofibroma without gross skin surface change was associated with a shorter pre-diagnosis duration than conventional dermatofibroma. Increase in size during the pre-diagnosis period was significantly more frequent in the conventional type. In addition, these dermatofibromas were more likely than the conventional type to occur in the head and neck region. Although tumor depth was deeper than in the conventional type, less than half of the dermatofibromas without gross skin surface change were found histologically to be "subcutaneous" or "deep-penetrating dermatofibroma". Subcutaneous extension was more frequent in these dermatofibromas while focal stromal hyalinization and hemosiderin deposits were more common in the conventional type. Limitations: This study is a retrospective, single center design. Conclusion : The present study suggests that dermatofibroma without gross skin surface change is a variant type with distinct clinical and histological features that distinguish them from conventional dermatofibroma.

  11. Dermatofibroma aneurismático

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    José Roberto Pegas

    2010-09-01

    Full Text Available Apresenta-se caso clínico de variante rara de dermatofibroma (tipo aneurismático em paciente do sexo feminino de 72 anos de idade, cuja lesão se localizava na dobra flexural do membro superior direito, resultante de proliferação mesenquimal associada à vasos sanguíneos e hemorragia tecidual, com características histológicas próprias e bem definidas. Os objetivos desta descrição foram a raridade da lesão e a importância que ela assume, do ponto de vista histopatológico, quando comparada no diagnóstico diferencial com outros tumores benignos e malignos e a terminologia utilizada atualmente.

  12. Dermatofibroma of the face: a clinicopathologic study of 20 cases.

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    Estela, J R; Rico, M T; Pérez, A; Unamuno, B; Garcías, J; Cubells, L; Alegre, V

    2014-03-01

    Dermatofibroma is one of the most common benign skin tumors. It typically develops on the lower limbs between the third and fifth decade of life and is more common in women. Clinical diagnosis is often straightforward. Dermatofibromas are associated with a very low rate of local recurrence following excision. To describe the clinical and histologic features of dermatofibroma of the face based on our experience. Descriptive retrospective study of the clinicopathologic features of dermatofibromas of the face diagnosed at the dermatology department of Hospital General Universitario de Valencia between 1990 and 2012. Twenty cases of dermatofibroma of the face (1.11% of all dermatofibromas diagnosed) were studied. The age at onset varied widely, from 28 to 84 years. The mean age at onset was 57.15 years and the median was 54 years. There were 11 women and 9 men. Mean follow-up was 83 months and there were no local recurrences. All the tumors were confined to the papillary and reticular dermis and the storiform pattern was the most common growth pattern observed. This study of facial dermatofibromas diagnosed at our hospital over a period of 22 years suggests that the face is an uncommon site but that dermatofibromas in this location behave similarly to those occurring elsewhere on the body. Copyright © 2013 Elsevier España, S.L. and AEDV. All rights reserved.

  13. Beyond classic dermoscopic patterns of dermatofibromas: a prospective research study.

    Science.gov (United States)

    Kelati, Awatef; Aqil, Nima; Baybay, Hanane; Gallouj, Salim; Mernissi, Fatima Zahra

    2017-09-20

    The usual stereotypical dermoscopic pattern associated with dermatofibromas is a pigment network and central white patch. However, this pattern may be difficult to diagnose in some variant cases. We aimed to describe dermoscopic patterns of dermatofibroma according to its histopathological subtypes, with special emphasis on new and rare dermoscopic features. This prospective study, which was conducted between September 2015 and May 2016 in the Department of Dermatology, University Hospital Hassan II, Fez, Morocco, included 100 cases of dermatofibroma confirmed on clinical and histological grounds. Each lesion was scored for classic, previously reported, or new dermoscopic features. All our Moroccan patients had a dark skin phototype (Fitzpatrick scale types IV and V). A total of 14 morphological dermoscopic structures were distinguished, and 17 dermoscopic patterns were observed, with the most common pattern being the central white patch and peripheral pigment network (21%). New patterns observed in our study were a white ring around an ulceration (6%), a pigment network with a pigmented ring around follicular openings (2%), and a discreet peripheral network and starlike white patch (3%). A patchy network with white patches was significantly noted in atrophic dermatofibroma (p = 0.01); vascularization was described in both aneurysmal and hemosiderotic dermatofibromas (p = 0.002); and a white ring around an ulceration was noted in aneurysmal dermatofibroma (p < 0.001). We provide a description of dermoscopic patterns of dermatofibroma according to its histological subtypes in a dark skin phototype, along with a new report of a white ring around an ulceration as a significant pattern in aneurysmal dermatofibroma.

  14. Dermatofibroma in a black tattoo: report of a case*

    Science.gov (United States)

    Bittencourt, Maraya de Jesus Semblano; de Miranda, Mario Fernando Ribeiro; de Parijós, Amanda Magno; Mesquita, Letícia Brito; da Fonseca, Diana Mendes; Jambo, Diego Augusto Aiezza

    2013-01-01

    Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was performed and the histopathological evaluation was consistent with dermatofibroma. Only three cases of dermatofibroma associated with tatooing were reported in litetature. We report an additional case and review the literature regarding cutaneous reactions to tattoos. PMID:24068136

  15. Dermatofibroma in a black tattoo: report of a case.

    Science.gov (United States)

    Bittencourt, Maraya de Jesus Semblano; Miranda, Mario Fernando Ribeiro de; Parijós, Amanda Magno de; Mesquita, Letícia Brito; Fonseca, Diana Mendes da; Jambo, Diego Augusto Aiezza

    2013-01-01

    Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was performed and the histopathological evaluation was consistent with dermatofibroma. Only three cases of dermatofibroma associated with tatooing were reported in literature. We report an additional case and review the literature regarding cutaneous reactions to tattoos.

  16. Spectropolarimetry of Giant stars: Probing the influence of magnetic field on evolved stars Spectropolarimetry of Giant stars: Probing the influence of magnetic field on evolved stars

    Science.gov (United States)

    da Costa, Jefferson; Castro, Matthieu; Petit, Pascal; do Nascimento, José-Dias, Jr.

    2015-08-01

    It is know that lithium is element easily destroyed in stellar interior, the existence of lithium rich stars means a great challenge in stellar evolution. In this context our observations ravels the serendipitous discovery of an unusually high lithium abundance star. This is a K0III HD 150050, which has strong deepening on lithium line (6707.8 Å) this means lithium abundance of 2.81 0.2 dex, therefore this star belong a rare group called super Li-Rich stars. A possible source of the non-standard episodes required to produce Li-rich stars were identified in magneto-thermohaline mixing accounted by models of extra-mixing induced by magnetic buoyancy. However to better understand this is necessary more observational data. In last three decades several studies has showed that late type red giant stars presents a remarkable modifications in these outer atmosphere layers when they become late type star in HR diagram. These changes are founded through X-ray, Ultraviolet, and Chromospheric activity analyses, and then we can establish the called “Dividing lines”. We made spectropalarimetric observations with ESPaDOnS@CFHT to achieve two main objectives: analyze the influence of magnetic field in the Li-rich giant stars, and understand how works the magnetic field in late type giants and supergiants across the “dividing line”.

  17. EVOLVE

    CERN Document Server

    Deutz, André; Schütze, Oliver; Legrand, Pierrick; Tantar, Emilia; Tantar, Alexandru-Adrian

    2017-01-01

    This book comprises nine selected works on numerical and computational methods for solving multiobjective optimization, game theory, and machine learning problems. It provides extended versions of selected papers from various fields of science such as computer science, mathematics and engineering that were presented at EVOLVE 2013 held in July 2013 at Leiden University in the Netherlands. The internationally peer-reviewed papers include original work on important topics in both theory and applications, such as the role of diversity in optimization, statistical approaches to combinatorial optimization, computational game theory, and cell mapping techniques for numerical landscape exploration. Applications focus on aspects including robustness, handling multiple objectives, and complex search spaces in engineering design and computational biology.

  18. On the Shoulders of Giants: Incremental Influence Maximization in Evolving Social Networks

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    Xiaodong Liu

    2017-01-01

    Full Text Available Influence maximization problem aims to identify the most influential individuals so as to help in developing effective viral marketing strategies over social networks. Previous studies mainly focus on designing efficient algorithms or heuristics on a static social network. As a matter of fact, real-world social networks keep evolving over time and a recalculation upon the changed network inevitably leads to a long running time. In this paper, we propose an incremental approach, IncInf, which can efficiently locate the top-K influential individuals in evolving social networks based on previous information instead of calculation from scratch. In particular, IncInf quantitatively analyzes the influence spread changes of nodes by localizing the impact of topology evolution to only local regions, and a pruning strategy is further proposed to narrow the search space into nodes experiencing major increases or with high degrees. To evaluate the efficiency and effectiveness, we carried out extensive experiments on real-world dynamic social networks: Facebook, NetHEPT, and Flickr. Experimental results demonstrate that, compared with the state-of-the-art static algorithm, IncInf achieves remarkable speedup in execution time while maintaining matching performance in terms of influence spread.

  19. Have giant lobelias evolved several times independently? Life form shifts and historical biogeography of the cosmopolitan and highly diverse subfamily Lobelioideae (Campanulaceae

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    Antonelli Alexandre

    2009-01-01

    Full Text Available Abstract Background The tendency of animals and plants to independently develop similar features under similar evolutionary pressures - convergence - is a widespread phenomenon in nature. In plants, convergence has been suggested to explain the striking similarity in life form between the giant lobelioids (Campanulaceae, the bellflower family of Africa and the Hawaiian Islands. Under this assumption these plants would have developed the giant habit from herbaceous ancestors independently, in much the same way as has been suggested for the giant senecios of Africa and the silversword alliance of Hawaii. Results Phylogenetic analyses based on plastid (rbcL, trnL-F and nuclear (internal transcribed spacer [ITS] DNA sequences for 101 species in subfamily Lobelioideae demonstrate that the large lobelioids from eastern Africa the Hawaiian Islands, and also South America, French Polynesia and southeast Asia, form a strongly supported monophyletic group. Ancestral state reconstructions of life form and distribution, taking into account phylogenetic uncertainty, indicate their descent from a woody ancestor that was probably confined to Africa. Molecular dating analyses using Penalized Likelihood and Bayesian relaxed clock approaches, and combining multiple calibration points, estimate their first diversification at ~25-33 million years ago (Ma, shortly followed by several long-distance dispersal events that resulted in the current pantropical distribution. Conclusion These results confidently show that lobelioid species, commonly called 'giant', are very closely related and have not developed their giant form from herbaceous ancestors independently. This study, which includes the hitherto largest taxon sampling for subfamily Lobelioideae, highlights the need for a broad phylogenetic framework for testing assumptions about morphological development in general, and convergent evolution in particular.

  20. SPOON-FEEDING GIANT STARS TO SUPERMASSIVE BLACK HOLES: EPISODIC MASS TRANSFER FROM EVOLVING STARS AND THEIR CONTRIBUTION TO THE QUIESCENT ACTIVITY OF GALACTIC NUCLEI

    Energy Technology Data Exchange (ETDEWEB)

    MacLeod, Morgan; Ramirez-Ruiz, Enrico; Grady, Sean; Guillochon, James, E-mail: mmacleod@ucolick.org [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2013-11-10

    Stars may be tidally disrupted if, in a single orbit, they are scattered too close to a supermassive black hole (SMBH). Tidal disruption events are thought to power luminous but short-lived accretion episodes that can light up otherwise quiescent SMBHs in transient flares. Here we explore a more gradual process of tidal stripping where stars approach the tidal disruption radius by stellar evolution while in an eccentric orbit. After the onset of mass transfer, these stars episodically transfer mass to the SMBH every pericenter passage, giving rise to low-level flares that repeat on the orbital timescale. Giant stars, in particular, will exhibit a runaway response to mass loss and 'spoon-feed' material to the black hole for tens to hundreds of orbital periods. In contrast to full tidal disruption events, the duty cycle of this feeding mode is of order unity for black holes M{sub bh} ∼> 10{sup 7} M{sub ☉}. This mode of quasi-steady SMBH feeding is competitive with indirect SMBH feeding through stellar winds, and spoon-fed giant stars may play a role in determining the quiescent luminosity of local SMBHs.

  1. Giant star seismology

    Science.gov (United States)

    Hekker, S.; Christensen-Dalsgaard, J.

    2017-06-01

    The internal properties of stars in the red-giant phase undergo significant changes on relatively short timescales. Long near-uninterrupted high-precision photometric timeseries observations from dedicated space missions such as CoRoT and Kepler have provided seismic inferences of the global and internal properties of a large number of evolved stars, including red giants. These inferences are confronted with predictions from theoretical models to improve our understanding of stellar structure and evolution. Our knowledge and understanding of red giants have indeed increased tremendously using these seismic inferences, and we anticipate that more information is still hidden in the data. Unraveling this will further improve our understanding of stellar evolution. This will also have significant impact on our knowledge of the Milky Way Galaxy as well as on exo-planet host stars. The latter is important for our understanding of the formation and structure of planetary systems.

  2. Gravity modes as a way to distinguish between hydrogen- and helium-burning red giant stars

    DEFF Research Database (Denmark)

    Bedding, Timothy R.; Mosser, Benoit; Huber, Daniel

    2011-01-01

    Red giants are evolved stars that have exhausted the supply of hydrogen in their cores and instead burn hydrogen in a surrounding shell. Once a red giant is sufficiently evolved, the helium in the core also undergoes fusion. Outstanding issues in our understanding of red giants include uncertaint...

  3. Gravity modes as a way to distinguish between hydrogen- and helium-burning red giant stars

    NARCIS (Netherlands)

    Bedding, T.R.; Mosser, B.; Huber, D.; Montalbán, J.; Beck, P.; Christensen-Dalsgaard, J.; Elsworth, Y.P.; García, R.A.; Miglio, A.; Stello, D.; White, T.R.; de Ridder, J.; Hekker, S.; Aerts, C.; Barban, C.; Belkacem, K.; Broomhall, A.M.; Brown, T.M.; Buzasi, D.L.; Carrier, F.; Chaplin, W.J.; Di Mauro, M.P.; Dupret, M.-A.; Frandsen, S.; Gilliland, R.L.; Goupil, M.J.; Jenkins, J.M.; Kallinger, T.; Kawaler, S.; Kjeldsen, H.; Mathur, S.; Noels, A.; Silva Aguirre, V.; Ventura, P.

    2011-01-01

    Red giants are evolved stars that have exhausted the supply of hydrogen in their cores and instead burn hydrogen in a surrounding shell. Once a red giant is sufficiently evolved, the helium in the core also undergoes fusion. Outstanding issues in our understanding of red giants include uncertainties

  4. Maintaining evolvability.

    Science.gov (United States)

    Crow, James F

    2008-12-01

    Although molecular methods, such as QTL mapping, have revealed a number of loci with large effects, it is still likely that the bulk of quantitative variability is due to multiple factors, each with small effect. Typically, these have a large additive component. Conventional wisdom argues that selection, natural or artificial, uses up additive variance and thus depletes its supply. Over time, the variance should be reduced, and at equilibrium be near zero. This is especially expected for fitness and traits highly correlated with it. Yet, populations typically have a great deal of additive variance, and do not seem to run out of genetic variability even after many generations of directional selection. Long-term selection experiments show that populations continue to retain seemingly undiminished additive variance despite large changes in the mean value. I propose that there are several reasons for this. (i) The environment is continually changing so that what was formerly most fit no longer is. (ii) There is an input of genetic variance from mutation, and sometimes from migration. (iii) As intermediate-frequency alleles increase in frequency towards one, producing less variance (as p --> 1, p(1 - p) --> 0), others that were originally near zero become more common and increase the variance. Thus, a roughly constant variance is maintained. (iv) There is always selection for fitness and for characters closely related to it. To the extent that the trait is heritable, later generations inherit a disproportionate number of genes acting additively on the trait, thus increasing genetic variance. For these reasons a selected population retains its ability to evolve. Of course, genes with large effect are also important. Conspicuous examples are the small number of loci that changed teosinte to maize, and major phylogenetic changes in the animal kingdom. The relative importance of these along with duplications, chromosome rearrangements, horizontal transmission and polyploidy

  5. Giant Magnetoresistance

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 4. Giant Magnetoresistance - Nobel Prize in Physics 2007. Debakanta Samal P S Anil Kumar. General Article Volume 13 Issue 4 April 2008 pp 343-354. Fulltext. Click here to view fulltext PDF. Permanent link:

  6. Giant lobelias exemplify convergent evolution

    Directory of Open Access Journals (Sweden)

    Givnish Thomas J

    2010-01-01

    Full Text Available Abstract Giant lobeliads on tropical mountains in East Africa and Hawaii have highly unusual, giant-rosette growth forms that appear to be convergent on each other and on those of several independently evolved groups of Asteraceae and other families. A recent phylogenetic analysis by Antonelli, based on sequencing the widest selection of lobeliads to date, raises doubts about this paradigmatic example of convergent evolution. Here I address the kinds of evidence needed to test for convergent evolution and argue that the analysis by Antonelli fails on four points. Antonelli's analysis makes several important contributions to our understanding of lobeliad evolution and geographic spread, but his claim regarding convergence appears to be invalid. Giant lobeliads in Hawaii and Africa represent paradigmatic examples of convergent evolution.

  7. Asymmetric evolving random networks

    Science.gov (United States)

    Coulomb, S.; Bauer, M.

    2003-10-01

    We generalize the Poissonian evolving random graph model of M. Bauer and D. Bernard (2003), to deal with arbitrary degree distributions. The motivation comes from biological networks, which are well-known to exhibit non Poissonian degree distributions. A node is added at each time step and is connected to the rest of the graph by oriented edges emerging from older nodes. This leads to a statistical asymmetry between incoming and outgoing edges. The law for the number of new edges at each time step is fixed but arbitrary. Thermodynamical behavior is expected when this law has a large time limit. Although (by construction) the incoming degree distributions depend on this law, this is not the case for most qualitative features concerning the size distribution of connected components, as long as the law has a finite variance. As the variance grows above 1/4, the average being < 1/2, a giant component emerges, which connects a finite fraction of the vertices. Below this threshold, the distribution of component sizes decreases algebraically with a continuously varying exponent. The transition is of infinite order, in sharp contrast with the case of static graphs. The local-in-time profiles for the components of finite size allow to give a refined description of the system.

  8. Transforming giants.

    Science.gov (United States)

    Kanter, Rosabeth Moss

    2008-01-01

    Large corporations have long been seen as lumbering, inflexible, bureaucratic--and clueless about global developments. But recently some multinationals seem to be transforming themselves: They're engaging employees, moving quickly, and introducing innovations that show true connection with the world. Harvard Business School's Kanter ventured with a research team inside a dozen global giants--including IBM, Procter & Gamble, Omron, CEMEX, Cisco, and Banco Real--to discover what has been driving the change. After conducting more than 350 interviews on five continents, she and her colleagues came away with a strong sense that we are witnessing the dawn of a new model of corporate power: The coordination of actions and decisions on the front lines now appears to stem from widely shared values and a sturdy platform of common processes and technology, not from top-down decrees. In particular, the values that engage the passions of far-flung workforces stress openness, inclusion, and making the world a better place. Through this shift in what might be called their guidance systems, the companies have become as creative and nimble as much smaller ones, even while taking on social and environmental challenges of a scale that only large enterprises could attempt. IBM, for instance, has created a nonprofit partnership, World Community Grid, through which any organization or individual can donate unused computing power to research projects and see what is being done with the donation in real time. IBM has gained an inspiring showcase for its new technology, helped business partners connect with the company in a positive way, and offered individuals all over the globe the chance to contribute to something big.

  9. Giant Cell Arteritis

    Science.gov (United States)

    Giant cell arteritis is a disorder that causes inflammation of your arteries, usually in the scalp, neck, and arms. ... arteries, which keeps blood from flowing well. Giant cell arteritis often occurs with another disorder called polymyalgia ...

  10. Evolvable synthetic neural system

    Science.gov (United States)

    Curtis, Steven A. (Inventor)

    2009-01-01

    An evolvable synthetic neural system includes an evolvable neural interface operably coupled to at least one neural basis function. Each neural basis function includes an evolvable neural interface operably coupled to a heuristic neural system to perform high-level functions and an autonomic neural system to perform low-level functions. In some embodiments, the evolvable synthetic neural system is operably coupled to one or more evolvable synthetic neural systems in a hierarchy.

  11. Seismology of Giant Planets: General Overview and Results from the Kepler K2 Observations of Neptune

    OpenAIRE

    Gaulme Patrick

    2017-01-01

    For this invited contribution, I was asked to give an overview about the application of helio and aster-oseismic techniques to study the interior of giant planets, and to specifically present the recent observations of Neptune by Kepler K2. Seismology applied to giant planets could drastically change our understanding of their deep interiors, as it has happened with the Earth, the Sun, and many main-sequence and evolved stars. The study of giant planets' composition is important for understan...

  12. Nanodielectrics with giant permittivity

    Indian Academy of Sciences (India)

    Following the prediction, during the last couple of years we have investigated the effect of giant permittivity in one-dimensional systems of conventional metals and conjugated polymer chains. In this article, we have tried to summarize the works on giant permittivity and finally the fabrication of nanocapacitor using metal ...

  13. Theory of Giant Planets

    Science.gov (United States)

    Hubbard, W. B.; Burrows, A.; Lunine, J. I.

    Giant planet research has moved from the study of a handful of solar system objects to that of a class of bodies with dozens of known members. Since the original 1995 discovery of the first extrasolar giant planets (EGPs), the total number of known examples has increased to ~80 (circa November 2001). Current theoretical studies of giant planets emphasize predicted observable properties, such as luminosity, effective temperature, radius, external gravity field, atmospheric composition, and emergent spectra as a function of mass and age. This review focuses on the general theory of hydrogen-rich giant planets; smaller giant planets with the mass and composition of Uranus and Neptune are not covered. We discuss the status of the theory of the nonideal thermodynamics of hydrogen and hydrogen-helium mixtures under the conditions found in giant-planet interiors, and the experimental constraints on it. We provide an overview of observations of extrasolar giant planets and our own giant planets by which the theory can be validated.

  14. Einstein Observatory magnitude-limited X-ray survey of late-type giant and supergiant stars

    Science.gov (United States)

    Maggio, A.; Vaiana, G. S.; Haisch, B. M.; Stern, R. A.; Bookbinder, J.

    1990-01-01

    Results are presented of an extensive X-ray survey of 380 giant and supergiant stars of spectral types from F to M, carried out with the Einstein Observatory. It was found that the observed F giants or subgiants (slightly evolved stars with a mass M less than about 2 solar masses) are X-ray emitters at the same level of main-sequence stars of similar spectral type. The G giants show a range of emissions more than 3 orders of magnitude wide; some single G giants exist with X-ray luminosities comparable to RS CVn systems, while some nearby large G giants have upper limits on the X-ray emission below typical solar values. The K giants have an observed X-ray emission level significantly lower than F and F giants. None of the 29 M giants were detected, except for one spectroscopic binary.

  15. Evolving digital ecological networks.

    Directory of Open Access Journals (Sweden)

    Miguel A Fortuna

    Full Text Available "It is hard to realize that the living world as we know it is just one among many possibilities" [1]. Evolving digital ecological networks are webs of interacting, self-replicating, and evolving computer programs (i.e., digital organisms that experience the same major ecological interactions as biological organisms (e.g., competition, predation, parasitism, and mutualism. Despite being computational, these programs evolve quickly in an open-ended way, and starting from only one or two ancestral organisms, the formation of ecological networks can be observed in real-time by tracking interactions between the constantly evolving organism phenotypes. These phenotypes may be defined by combinations of logical computations (hereafter tasks that digital organisms perform and by expressed behaviors that have evolved. The types and outcomes of interactions between phenotypes are determined by task overlap for logic-defined phenotypes and by responses to encounters in the case of behavioral phenotypes. Biologists use these evolving networks to study active and fundamental topics within evolutionary ecology (e.g., the extent to which the architecture of multispecies networks shape coevolutionary outcomes, and the processes involved.

  16. Metaphyseal giant cell tumor

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, L.F.; Hemais, P.M.P.G.; Aymore, I.L.; Carmo, M.C.R. do; Cunha, M.E.P.R. da; Resende, C.M.C.

    Three cases of metaphyseal giant cell tumor are presented. A review of the literature is done, demostrating the lesion is rare and that there are few articles about it. Age incidence and characteristics of the tumor are discussed.

  17. Giant omphalocele: current perspectives

    National Research Council Canada - National Science Library

    Mack AJ; Rogdo B

    2016-01-01

    Alexander Josef Mack,1 Bjarte Rogdo2 1Department of Pediatric Surgery, 2Pediatric and Neonatal Intensive Care Unit, Children's Hospital of Eastern Switzerland, St Gallen, Switzerland Abstract: Giant omphalocele (GO...

  18. ON THE NATURE OF RAPIDLY ROTATING SINGLE EVOLVED STARS

    Energy Technology Data Exchange (ETDEWEB)

    Da Silva, R. Rodrigues; Canto Martins, B. L.; De Medeiros, J. R., E-mail: renan@dfte.ufrn.br [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Campus Universitário, Natal RN (Brazil)

    2015-03-01

    We present an analysis of the nature of the rapidly rotating, apparently single giant based on rotational and radial velocity measurements carried out by the CORAVEL spectrometers. From the analyzed sample, composed of 2010 spectroscopic, apparently single, evolved stars of luminosity classes IV, III, II, and Ib with spectral types G and K, we classified 30 stars that presented unusual, moderate to rapid rotation. This work reports, for the first time, the presence of these abnormal rotators among subgiant, bright giant, and Ib supergiant stars. To date, this class of stars was reported only among giant stars of luminosity class III. Most of these abnormal rotators present an IRAS infrared excess, which, in principle, can be related to dust around these stars.

  19. Giant peritoneal loose bodies

    Directory of Open Access Journals (Sweden)

    Chris van Zyl

    2015-03-01

    Full Text Available Giant peritoneal loose bodies are rare lesions, originating from auto-amputated appendices epiploicae. They may cause urinary or gastrointestinal obstruction and, should the radiologist not be familiar with the entity, can potentially be confused with malignant or parasitic lesions.Familiarity with their characteristic computed tomographic features is essential to prevent unnecessary surgery in the asymptomatic patient. We present a case of a 70-year-old man diagnosed with two giant peritoneal loose bodies.

  20. Preequilibrium escape widths of giant resonances

    Science.gov (United States)

    Roos, M. O.; Dias, H.; Rodriguez, O.; Teruya, N.; Hussein, M. S.

    2002-08-01

    In this work we present a calculation of the 2p-2h preequilibrium escape width of giant resonances for the nuclei 40Ca, 90Zr, and 208Pb. The problem studied here involves an excited nucleus in the 1p-1h configuration, evolving to the 2p-2h configuration with the 1p in the continuum. The theoretical approach used for our calculations is based on the statistical multistep compound theory of Feshbach, Kerman, and Koonin (FKK) and on the particle-hole state densities given by Obložinský. Our calculations show that although different state densities supply a similar result for the damping width, the escape width is strongly dependent on the nuclei, on the binding energy of the emitted nucleon, and the excitation energy of the giant resonance.

  1. Multinucleated giant cells.

    Science.gov (United States)

    Anderson, J M

    2000-01-01

    Recent studies directed toward developing a better understanding of the molecular and cellular biology basis of monocyte-derived multinucleated giant cell formation, function, and biologic activity are presented. In addition, HIV-1-infected T-lymphocyte syncytia and the significance of adhesion molecule/ligand interactions in the formation of these syncytia are described. Interleukin-4 or interleukin-13 induction of monocyte-macrophage fusion provides a model for foreign body giant cell formation. On the other hand, interferon-gamma induction of monocyte-macrophage fusion provides a model for Langhans' giant cell formation. Variations in monocyte-macrophage adhesion and fusion to form foreign body giant cells are provided by substrates with different surface chemistries. Recent advances in osteoclast biology have identified the role of tumor necrosis factor-alpha in regulating osteoclast bone resorption and receptor-ligand interactions and signal pathways for osteoclast activation. Although foreign body giant cells, Langhans' giant cells, and osteoclasts are derived from monocytes or monocyte progenitor cells, the ways in which they are formed, whether induced by cytokines, receptors, or biologic activity, are markedly different.

  2. A catalog of rotational and radial velocities for evolved stars. V. Southern stars

    OpenAIRE

    {De Medeiros} J.~R.; {Alves} S.; {Udry} S.; {Andersen} J.; {Nordström}} B.; {Mayor} M.

    2014-01-01

    Rotational and radial velocities have been measured for 1589 evolved stars of spectral types F, G and K and luminosity classes IV, III, II and Ib, based on observations carried out with the CORAVEL spectrometers. The precision in radial velocity is better than 0.30 km/s per observation, whereas rotational velocity uncertainties are typically 1.0 km/s for subgiants and giants and 2.0 km/s for class II giants and Ib supergiants.

  3. Mentoring: An Evolving Relationship.

    Science.gov (United States)

    Block, Michelle; Florczak, Kristine L

    2017-04-01

    The column concerns itself with mentoring as an evolving relationship between mentor and mentee. The collegiate mentoring model, the transformational transcendence model, and the humanbecoming mentoring model are considered in light of a dialogue with mentors at a Midwest university and conclusions are drawn.

  4. Measurably evolving populations

    DEFF Research Database (Denmark)

    Drummond, Alexei James; Pybus, Oliver George; Rambaut, Andrew

    2003-01-01

    processes through time. Populations for which such studies are possible � measurably evolving populations (MEPs) � are characterized by sufficiently long or numerous sampled sequences and a fast mutation rate relative to the available range of sequence sampling times. The impact of sequences sampled through...... understanding of evolutionary processes in diverse organisms, from viruses to vertebrates....

  5. Rapidly rotating red giants

    Science.gov (United States)

    Gehan, Charlotte; Mosser, Benoît; Michel, Eric

    2017-10-01

    Stellar oscillations give seismic information on the internal properties of stars. Red giants are targets of interest since they present mixed modes, wich behave as pressure modes in the convective envelope and as gravity modes in the radiative core. Mixed modes thus directly probe red giant cores, and allow in particular the study of their mean core rotation. The high-quality data obtained by CoRoT and Kepler satellites represent an unprecedented perspective to obtain thousands of measurements of red giant core rotation, in order to improve our understanding of stellar physics in deep stellar interiors. We developed an automated method to obtain such core rotation measurements and validated it for stars on the red giant branch. In this work, we particularly focus on the specific application of this method to red giants having a rapid core rotation. They show complex spectra where it is tricky to disentangle rotational splittings from mixed-mode period spacings. We demonstrate that the method based on the identification of mode crossings is precise and efficient. The determination of the mean core rotation directly derives from the precise measurement of the asymptotic period spacing ΔΠ1 and of the frequency at which the crossing of the rotational components is observed.

  6. Giant inguinoscrotal hernia repair.

    Science.gov (United States)

    Prochotsky, A; Dolak, S; Minarovjech, V; Medzo, I; Hutan, M; Mifkovic, A

    2017-01-01

    Giant inguinoscrotal hernia is defined as an inguinal hernia extending below the midpoint of inner thigh in standing position. The authors describe giant inguinoscrotal hernia and small umbilical hernia with 12 years history of this uncommon disease. After preoperative evaluation, US and CT examination he was operated on. It was very difficult to return the hernia sac contents back to the abdomen and additional infraumbilical incision was needed. Hernioplasty suo modo without mesh was done. Patient recovered uneventfully. In the discussion the authors present the newer classification of giant inguinal hernia, the current treatment options and known serious complications of surgery. Finally, it indicates that good treatment results can only be achieved by close cooperation of concerned professionals in the treatment and intensive intraoperative and postoperative patient monitoring (Fig. 9, Ref. 31).

  7. Congenital giant melanocytic nevi

    Directory of Open Access Journals (Sweden)

    Shahla Khan

    2009-07-01

    Full Text Available Nevi are common skin tumors caused by abnormal overgrowth of cells from the epidermal and dermal layers of the skin. Most nevi are benign, but some pre-cancerous nevi must be monitored or removed. The giant congenital nevus is greater than 10 cm in size, pigmented and often hairy. Between 4% and 6% of these lesions will develop into a malignant melanoma. Since approximately 50% of the melanoma develop by the age of two, and 80% by the age of seven, early removal is recommended. The objective of this paper is to present a unique case of giant nevi and their surgical management.

  8. EVOLVE 2014 International Conference

    CERN Document Server

    Tantar, Emilia; Sun, Jian-Qiao; Zhang, Wei; Ding, Qian; Schütze, Oliver; Emmerich, Michael; Legrand, Pierrick; Moral, Pierre; Coello, Carlos

    2014-01-01

    This volume encloses research articles that were presented at the EVOLVE 2014 International Conference in Beijing, China, July 1–4, 2014.The book gathers contributions that emerged from the conference tracks, ranging from probability to set oriented numerics and evolutionary computation; all complemented by the bridging purpose of the conference, e.g. Complex Networks and Landscape Analysis, or by the more application oriented perspective. The novelty of the volume, when considering the EVOLVE series, comes from targeting also the practitioner’s view. This is supported by the Machine Learning Applied to Networks and Practical Aspects of Evolutionary Algorithms tracks, providing surveys on new application areas, as in the networking area and useful insights in the development of evolutionary techniques, from a practitioner’s perspective. Complementary to these directions, the conference tracks supporting the volume, follow on the individual advancements of the subareas constituting the scope of the confe...

  9. Evolvable Neural Software System

    Science.gov (United States)

    Curtis, Steven A.

    2009-01-01

    The Evolvable Neural Software System (ENSS) is composed of sets of Neural Basis Functions (NBFs), which can be totally autonomously created and removed according to the changing needs and requirements of the software system. The resulting structure is both hierarchical and self-similar in that a given set of NBFs may have a ruler NBF, which in turn communicates with other sets of NBFs. These sets of NBFs may function as nodes to a ruler node, which are also NBF constructs. In this manner, the synthetic neural system can exhibit the complexity, three-dimensional connectivity, and adaptability of biological neural systems. An added advantage of ENSS over a natural neural system is its ability to modify its core genetic code in response to environmental changes as reflected in needs and requirements. The neural system is fully adaptive and evolvable and is trainable before release. It continues to rewire itself while on the job. The NBF is a unique, bilevel intelligence neural system composed of a higher-level heuristic neural system (HNS) and a lower-level, autonomic neural system (ANS). Taken together, the HNS and the ANS give each NBF the complete capabilities of a biological neural system to match sensory inputs to actions. Another feature of the NBF is the Evolvable Neural Interface (ENI), which links the HNS and ANS. The ENI solves the interface problem between these two systems by actively adapting and evolving from a primitive initial state (a Neural Thread) to a complicated, operational ENI and successfully adapting to a training sequence of sensory input. This simulates the adaptation of a biological neural system in a developmental phase. Within the greater multi-NBF and multi-node ENSS, self-similar ENI s provide the basis for inter-NBF and inter-node connectivity.

  10. Social waves in giant honeybees repel hornets.

    Directory of Open Access Journals (Sweden)

    Gerald Kastberger

    Full Text Available Giant honeybees (Apis dorsata nest in the open and have evolved a plethora of defence behaviors. Against predatory wasps, including hornets, they display highly coordinated Mexican wave-like cascades termed 'shimmering'. Shimmering starts at distinct spots on the nest surface and then spreads across the nest within a split second whereby hundreds of individual bees flip their abdomens upwards. However, so far it is not known whether prey and predator interact and if shimmering has anti-predatory significance. This article reports on the complex spatial and temporal patterns of interaction between Giant honeybee and hornet exemplified in 450 filmed episodes of two A. dorsata colonies and hornets (Vespa sp.. Detailed frame-by-frame analysis showed that shimmering elicits an avoidance response from the hornets showing a strong temporal correlation with the time course of shimmering. In turn, the strength and the rate of the bees' shimmering are modulated by the hornets' flight speed and proximity. The findings suggest that shimmering creates a 'shelter zone' of around 50 cm that prevents predatory wasps from foraging bees directly from the nest surface. Thus shimmering appears to be a key defence strategy that supports the Giant honeybees' open-nesting life-style.

  11. Social Waves in Giant Honeybees Repel Hornets

    Science.gov (United States)

    Kastberger, Gerald; Schmelzer, Evelyn; Kranner, Ilse

    2008-01-01

    Giant honeybees (Apis dorsata) nest in the open and have evolved a plethora of defence behaviors. Against predatory wasps, including hornets, they display highly coordinated Mexican wave-like cascades termed ‘shimmering’. Shimmering starts at distinct spots on the nest surface and then spreads across the nest within a split second whereby hundreds of individual bees flip their abdomens upwards. However, so far it is not known whether prey and predator interact and if shimmering has anti-predatory significance. This article reports on the complex spatial and temporal patterns of interaction between Giant honeybee and hornet exemplified in 450 filmed episodes of two A. dorsata colonies and hornets (Vespa sp.). Detailed frame-by-frame analysis showed that shimmering elicits an avoidance response from the hornets showing a strong temporal correlation with the time course of shimmering. In turn, the strength and the rate of the bees' shimmering are modulated by the hornets' flight speed and proximity. The findings suggest that shimmering creates a ‘shelter zone’ of around 50 cm that prevents predatory wasps from foraging bees directly from the nest surface. Thus shimmering appears to be a key defence strategy that supports the Giant honeybees' open-nesting life-style. PMID:18781205

  12. Clinical and Histologic Features of 26 Canine Peripheral Giant Cell Granulomas (Formerly Giant Cell Epulis)

    National Research Council Canada - National Science Library

    Desoutter, A. V; Goldschmidt, M. H; Sánchez, M. D

    2012-01-01

    ... (formerly giant cell epulis) are reported. Two main histologic categories were evident: (1) “classic” peripheral giant cell granuloma, characterized by variable numbers of multinucleated giant cells...

  13. Juvenile giant fibroadenoma

    Directory of Open Access Journals (Sweden)

    Vipul Yagnik

    2011-07-01

    Full Text Available Fibroadenomas are benign solid tumor associated with aberration of normal lobular development. Juvenile giant fibroadenoma is usually single and >5 cm in size /or >500 gms in weight. Important differential diagnoses are: phyllodes tumor and juvenile gigantomastia. Simple excision is the treatment of choice.

  14. from the Giant Panda

    African Journals Online (AJOL)

    STORAGESEVER

    2009-06-03

    Jun 3, 2009 ... RPS28 is a component of the 40S small ribosomal subunit encoded by RPS28 gene, which is specific to eukaryotes. The cDNA and the genomic sequence of RPS28 were cloned successfully from the Giant. Panda using RT-PCR technology and Touchdown-PCR, respectively. Both sequences were ...

  15. Giant peritoneal loose bodies

    African Journals Online (AJOL)

    2015-03-27

    Mar 27, 2015 ... Giant peritoneal loose bodies are rare lesions, originating from auto-amputated appendices epiploicae. They may cause urinary or gastrointestinal obstruction and, should the radiologist not be familiar with the entity, can potentially be confused with malignant or parasitic lesions. Familiarity with their ...

  16. Graphenes – Aromatic Giants

    Indian Academy of Sciences (India)

    Graphenes – Aromatic Giants. (benzene) rings. Until recently it was believed [5] that their chemical investigations are limited to compounds with not more than 15 rings. The reason for this is based on the fact that large. PAHs are practically insoluble in water or organic solvents, which makes their purification and chemical ...

  17. Graphenes–Aromatic Giants

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 13; Issue 8. Graphenes – Aromatic Giants. Ivan Gutman Boris Furtula. General Article Volume 13 Issue 8 August 2008 pp 730-737. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/013/08/0730-0737 ...

  18. Graphenes–Aromatic Giants

    Indian Academy of Sciences (India)

    Graphenes - Aromatic Giants. Ivan Gutman Boris Furtula. Volume 16 Issue 12 December 2011 pp 1238-1245. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/016/12/1238-1245. Keywords. Graphenes; polycyclic aromatic hydrocarbons; polyphenyls; condensed benzenes.

  19. Regolith Evolved Gas Analyzer

    Science.gov (United States)

    Hoffman, John H.; Hedgecock, Jud; Nienaber, Terry; Cooper, Bonnie; Allen, Carlton; Ming, Doug

    2000-01-01

    The Regolith Evolved Gas Analyzer (REGA) is a high-temperature furnace and mass spectrometer instrument for determining the mineralogical composition and reactivity of soil samples. REGA provides key mineralogical and reactivity data that is needed to understand the soil chemistry of an asteroid, which then aids in determining in-situ which materials should be selected for return to earth. REGA is capable of conducting a number of direct soil measurements that are unique to this instrument. These experimental measurements include: (1) Mass spectrum analysis of evolved gases from soil samples as they are heated from ambient temperature to 900 C; and (2) Identification of liberated chemicals, e.g., water, oxygen, sulfur, chlorine, and fluorine. REGA would be placed on the surface of a near earth asteroid. It is an autonomous instrument that is controlled from earth but does the analysis of regolith materials automatically. The REGA instrument consists of four primary components: (1) a flight-proven mass spectrometer, (2) a high-temperature furnace, (3) a soil handling system, and (4) a microcontroller. An external arm containing a scoop or drill gathers regolith samples. A sample is placed in the inlet orifice where the finest-grained particles are sifted into a metering volume and subsequently moved into a crucible. A movable arm then places the crucible in the furnace. The furnace is closed, thereby sealing the inner volume to collect the evolved gases for analysis. Owing to the very low g forces on an asteroid compared to Mars or the moon, the sample must be moved from inlet to crucible by mechanical means rather than by gravity. As the soil sample is heated through a programmed pattern, the gases evolved at each temperature are passed through a transfer tube to the mass spectrometer for analysis and identification. Return data from the instrument will lead to new insights and discoveries including: (1) Identification of the molecular masses of all of the gases

  20. A giant planet around the massive giant star HD 13189

    Science.gov (United States)

    Hatzes, A. P.; Guenther, E. W.; Endl, M.; Cochran, W. D.; Döllinger, M. P.; Bedalov, A.

    2005-07-01

    Most extrasolar planet discoveries using radial velocity measurements have been for solar-like G-stars. In order to understand better the role stellar mass for the formation of planets we must learn more about the frequency of planetary companions around both high- and low-mass stars. Radial velocity searches for planets around high mass main-sequence stars are difficult due to the paucity of lines and often rapid rotation of these early-type stars. On the other hand, evolved stars that have moved off the main sequence offer us the possibility of searching for planets around higher mass stars by means of precise radial velocity measurements. Here we present radial velocity measurements for the star HD 13189 using measurements taken at the Thüringer Landessternwarte Tautenburg, the Harlan J. Smith Telescope at McDonald Observatory, and the Hobby-Eberly Telescope. We classify the spectral type of this star as K2 with luminosity class II. The radial velocity measurements show long-period variations with a period of 472 days and an amplitude of 173 m s-1. The Ca II S-index is consistent with an inactive star and this shows no variations with the radial velocity period. We also investigated possible changes in the line shapes by measuring spectral line bisectors. These show no variations with the radial velocity period. We interpret the 472-day period as being caused by a sub-stellar companion. Based on the estimated absolute magnitude and a comparison to evolutionary tracks we estimate the mass of the progenitor star between 2 and 7 M_⊙ which results in a projected mass of the companion of m sin i = 8 20 M_J. HD 13189 may be the most massive star known to possess an extrasolar planet. This suggests that the formation of giant planets can also occur around early-type stars. HD 13189 also shows significant short term radial velocity variability on time scales of days that is most likely due to stellar oscillations. This behavior is typical for K giant stars.

  1. Sulfur and zinc abundances of red giant stars†

    Science.gov (United States)

    Takeda, Yoichi; Omiya, Masashi; Harakawa, Hiroki; Sato, Bun'ei

    2016-10-01

    Sulfur and zinc are chemically volatile elements, which play significant roles as depletion-free tracers in studying galactic chemical evolution. However, regarding red giants having evolved off the main sequence, reliable abundance determinations of S and Zn seem to be difficult, despite the several studies that have been reported so far. Given this situation, we tried to establish the abundances of these elements for an extensive sample of 239 field GK giants ( - 0.8 ≲ [Fe/H] ≲ +0.2), by applying the spectrum-fitting technique to S I 8694-5, S I 6757, and Zn I 6362 lines and by taking into account the non-LTE effect. Besides, similar abundance analysis was done for 160 FGK dwarfs to be used for comparison. The non-LTE corrections for the S and Zn abundances derived from these lines turned out to be ≲ 0.1(-0.2) dex for most cases and not very significant. It revealed that the S I 6757 feature is more reliable as an abundance indicator than S I 8694-5 for the case of red giants, because the latter suffers blending of unidentified lines. The finally resulting [S/Fe]-[Fe/H] and [Zn/Fe]-[Fe/H] relations for GK giants were confirmed to be in good agreement with those for FGK dwarfs, indicating that S and Zn abundances of red giants are reliably determinable from the S I 6757 and Zn I 6362 lines. Accordingly, not only main-sequence stars but also evolved red giant stars are usable for tracing the chemical evolution history of S and Zn in the regime of disk metallicity by using these lines.

  2. Photospheric Diagnostics of Core Helium Burning in Giant Stars

    Science.gov (United States)

    Hawkins, Keith; Ting, Yuan-Sen; Walter-Rix, Hans

    2018-01-01

    Core helium burning primary red clump (RC) stars are evolved red giant stars that are excellent standard candles. As such, these stars are routinely used to map the Milky Way or determine the distance to other galaxies, among other things. However, distinguishing RC stars from their less evolved precursors, namely red giant branch (RGB) stars, is still a difficult challenge and has been deemed the domain of asteroseismology. In this paper, we use a sample of 1676 RGB and RC stars that have both single epoch infrared spectra from the APOGEE survey and asteroseismic parameters and classification to show that the spectra alone can be used to (1) predict asteroseismic parameters with precision high enough to (2) distinguish core helium burning RC from other giant stars with less than 2% contamination. This will not only allow for a clean selection of a large number of standard candles across our own and other galaxies from spectroscopic surveys, but also will remove one of the primary roadblocks for stellar evolution studies of mixing and mass loss in red giant stars.

  3. Giant Otters in Peru

    OpenAIRE

    Schenk C.; Staib E.

    1992-01-01

    We are in the second year of fieldwork surveying for Giant Otters in the southeastern rainforest of Peru, in three areas with differing levels of legal protection. While there is some illegal hunting still happening outside the protected areas, the main threat to the otters is badly-conducted tourism. Well-organised tourism can be a promising argument for establishing protected areas like national parks.

  4. Intraoral giant condyloma acuminatum

    Directory of Open Access Journals (Sweden)

    Gupta R

    2001-09-01

    Full Text Available A case of intraoral giant condyloma acuminatum is reported in a 50- year- old Indian. He did not respond to topical application of podophyllin 20% but responded partially to electric cauterisation. Surgical excision was done to get rid of the warty growh completely. Since there were no skin or genital lesions and no history of marital or extramarital sexual contact the lesion was probably acquired from environmental sources. Nonsexual transmission should be considered especially when the lesions are extragenital.

  5. Giant prolactinomas in women

    DEFF Research Database (Denmark)

    Delgrange, Etienne; Raverot, Gerald; Bex, Marie

    2014-01-01

    OBJECTIVE: To characterise distinctive clinical features of giant prolactinomas in women. DESIGN: A multicentre, retrospective case series and literature review. METHODS: We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg/l and id......OBJECTIVE: To characterise distinctive clinical features of giant prolactinomas in women. DESIGN: A multicentre, retrospective case series and literature review. METHODS: We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg....../l and identified 19 similar cases from the literature; a gender-based comparison of the frequency and age distribution was obtained from a literature review. RESULTS: The initial PubMed search using the term 'giant prolactinomas' identified 125 patients (13 women) responding to the inclusion criteria. The female......:male ratio was 1:9. Another six female patients were found by extending the literature search, while our own series added 15 patients. The median age at diagnosis was 44 years in women compared with 35 years in men (P

  6. A simple model to describe intrinsic stellar noise for exoplanet detection around red giants

    DEFF Research Database (Denmark)

    North, Thomas S. H.; Chaplin, William J.; Gilliland, Ronald L.

    2017-01-01

    In spite of the huge advances in exoplanet research provided by the NASA Kepler Mission, there remain only a small number of transit detections around evolved stars. Here, we present a reformulation of the noise properties of red-giant stars, where the intrinsic stellar granulation and the stellar...... of stellar noise for these missions. As an application of our noise model, we explore the minimum detectable planet radii for red giant stars, and find that Neptune-sized planets should be detectable around low-luminosity red giant branch stars....

  7. Fat: an evolving issue

    Directory of Open Access Journals (Sweden)

    John R. Speakman

    2012-09-01

    Work on obesity is evolving, and obesity is a consequence of our evolutionary history. In the space of 50 years, we have become an obese species. The reasons why can be addressed at a number of different levels. These include separating between whether the primary cause lies on the food intake or energy expenditure side of the energy balance equation, and determining how genetic and environmental effects contribute to weight variation between individuals. Opinion on whether increased food intake or decreased energy expenditure drives the obesity epidemic is still divided, but recent evidence favours the idea that food intake, rather than altered expenditure, is most important. There is more of a consensus that genetics explains most (probably around 65% of weight variation between individuals. Recent advances in genome-wide association studies have identified many polymorphisms that are linked to obesity, yet much of the genetic variance remains unexplained. Finding the causes of this unexplained variation will be an impetus of genetic and epigenetic research on obesity over the next decade. Many environmental factors – including gut microbiota, stress and endocrine disruptors – have been linked to the risk of developing obesity. A better understanding of gene-by-environment interactions will also be key to understanding obesity in the years to come.

  8. Evolving Concepts of Asthma

    Science.gov (United States)

    Ray, Anuradha; Wenzel, Sally E.

    2015-01-01

    Our understanding of asthma has evolved over time from a singular disease to a complex of various phenotypes, with varied natural histories, physiologies, and responses to treatment. Early therapies treated most patients with asthma similarly, with bronchodilators and corticosteroids, but these therapies had varying degrees of success. Similarly, despite initial studies that identified an underlying type 2 inflammation in the airways of patients with asthma, biologic therapies targeted toward these type 2 pathways were unsuccessful in all patients. These observations led to increased interest in phenotyping asthma. Clinical approaches, both biased and later unbiased/statistical approaches to large asthma patient cohorts, identified a variety of patient characteristics, but they also consistently identified the importance of age of onset of disease and the presence of eosinophils in determining clinically relevant phenotypes. These paralleled molecular approaches to phenotyping that developed an understanding that not all patients share a type 2 inflammatory pattern. Using biomarkers to select patients with type 2 inflammation, repeated trials of biologics directed toward type 2 cytokine pathways saw newfound success, confirming the importance of phenotyping in asthma. Further research is needed to clarify additional clinical and molecular phenotypes, validate predictive biomarkers, and identify new areas for possible interventions. PMID:26161792

  9. Evolving endoscopic surgery.

    Science.gov (United States)

    Sakai, Paulo; Faintuch, Joel

    2014-06-01

    Since the days of Albukasim in medieval Spain, natural orifices have been regarded not only as a rather repugnant source of bodily odors, fluids and excreta, but also as a convenient invitation to explore and treat the inner passages of the organism. However, surgical ingenuity needed to be matched by appropriate tools and devices. Lack of technologically advanced instrumentation was a strong deterrent during almost a millennium until recent decades when a quantum jump materialized. Endoscopic surgery is currently a vibrant and growing subspecialty, which successfully handles millions of patients every year. Additional opportunities lie ahead which might benefit millions more, however, requiring even more sophisticated apparatuses, particularly in the field of robotics, artificial intelligence, and tissue repair (surgical suturing). This is a particularly exciting and worthwhile challenge, namely of larger and safer endoscopic interventions, followed by seamless and scarless recovery. In synthesis, the future is widely open for those who use together intelligence and creativity to develop new prototypes, new accessories and new techniques. Yet there are many challenges in the path of endoscopic surgery. In this new era of robotic endoscopy, one will likely need a virtual simulator to train and assess the performance of younger doctors. More evidence will be essential in multiple evolving fields, particularly to elucidate whether more ambitious and complex pathways, such as intrathoracic and intraperitoneal surgery via natural orifice transluminal endoscopic surgery (NOTES), are superior or not to conventional techniques. © 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.

  10. Evolving a photosynthetic organelle

    Directory of Open Access Journals (Sweden)

    Nakayama Takuro

    2012-04-01

    Full Text Available Abstract The evolution of plastids from cyanobacteria is believed to represent a singularity in the history of life. The enigmatic amoeba Paulinella and its 'recently' acquired photosynthetic inclusions provide a fascinating system through which to gain fresh insight into how endosymbionts become organelles. The plastids, or chloroplasts, of algae and plants evolved from cyanobacteria by endosymbiosis. This landmark event conferred on eukaryotes the benefits of photosynthesis - the conversion of solar energy into chemical energy - and in so doing had a huge impact on the course of evolution and the climate of Earth 1. From the present state of plastids, however, it is difficult to trace the evolutionary steps involved in this momentous development, because all modern-day plastids have fully integrated into their hosts. Paulinella chromatophora is a unicellular eukaryote that bears photosynthetic entities called chromatophores that are derived from cyanobacteria and has thus received much attention as a possible example of an organism in the early stages of organellogenesis. Recent studies have unlocked the genomic secrets of its chromatophore 23 and provided concrete evidence that the Paulinella chromatophore is a bona fide photosynthetic organelle 4. The question is how Paulinella can help us to understand the process by which an endosymbiont is converted into an organelle.

  11. Cytogenetic and molecular genetic analyses of giant cell glioblastoma multiforme reveal distinct profiles in giant cell and non-giant cell subpopulations.

    Science.gov (United States)

    Martinez, Ramon; Roggendorf, Wolfgang; Baretton, Gustavo; Klein, Rüdiger; Toedt, Grisha; Lichter, Peter; Schackert, Gabriele; Joos, Stefan

    2007-05-01

    We have comparatively analyzed mechanisms associated with chromosomal and microsatellite instability in giant cell glioblastoma multiforme (gcGBM) and classic GBM. This included microsatellite instability (MSI), loss of expression of four major mismatch repair (MMR) proteins, aberrations of five chromosomes, EGFR copy number, and TP53 mutations. MSI was more frequent among gcGBM (30 vs. 7.8%, P = 0.054). TP53 mutations were more commonly observed in gcGBM (83.3%), whereas EGFR was amplified in just one gcGBM (8.3%). By tumor cell phenotype-specific cytogenetic analysis of gcGBM, increased chromosome copy numbers were identified in 72-84% of giant cells but in only 4-14% of nongiant cells; in classic GBM, intermediate frequencies were noted (11-49%). Chromosome 10 deletions were found in nongiant cells of all gcGBM cases but in only approximately 45% of the cell population in classic GBM. The present study shows a distinct pattern of cytogenetic alterations in nongiant and giant cell phenotypes in gcGBM and suggests that multinuclear giant cells evolve from nongiant tumor cells at an early tumor stage. Furthermore, the data point to differences in the profile of chromosomal and microsatellite instability in gcGBM and classic GBM that might underscore the distinct pathological features of both tumor subtypes.

  12. Giant scalp arteriovenous malformation.

    Science.gov (United States)

    Worm, Paulo Valdeci; Ruschel, Leonardo Gilmone; Roxo, Marcelo Rosa; Camelo, Rafael

    2016-12-01

    Arteriovenous malformations (AVMs) of the scalp are rare lesions. The clinical picture presents with complaints of increased scalp, scalp disfigurement, pain and neurological symptoms. Its origin can be congenital or traumatic. We present a case of giant scalp AVMs and its management, followed by a brief literature review on the subject. The diagnosis of scalp AVMs is based on physical examination and confirmed by internal and external carotid angiography or computed tomographic angiography (CTA). Surgical excision is especially effective in scalp AVMs, and is the most frequently used treatment modality.

  13. A Giant Urethral Calculus.

    Science.gov (United States)

    Sigdel, G; Agarwal, A; Keshaw, B W

    2014-01-01

    Urethral calculi are rare forms of urolithiasis. Majority of the calculi are migratory from urinary bladder or upper urinary tract. Primary urethral calculi usually occur in presence of urethral stricture or diverticulum. In this article we report a case of a giant posterior urethral calculus measuring 7x3x2 cm in a 47 years old male. Patient presented with acute retention of urine which was preceded by burning micturition and dribbling of urine for one week. The calculus was pushed in to the bladder through the cystoscope and was removed by suprapubic cystolithotomy.

  14. GIANT PROSTHETIC VALVE THROMBUS

    Directory of Open Access Journals (Sweden)

    Prashanth Kumar

    2015-04-01

    Full Text Available Mechanical prosthetic valves are predisposed to bleeding, thrombosis & thromboembolic complications. Overall incidence of thromboembolic complications is 1% per year who are on oral anticoagulants, whereas bleeding complications incidence is 0.5% to 6.6% per year. 1, 2 Minimization of Scylla of thromboembolic & Charybdis of bleeding complication needs a balancing act of optimal antithrombotic therapy. We are reporting a case of middle aged male patient with prosthetic mitral valve presenting in heart failure. Patient had discontinued anticoagulants, as he had subdural hematoma in the past. He presented to our institute with a giant prosthetic valve thrombus.

  15. Giant paraganglioma in

    Directory of Open Access Journals (Sweden)

    Alka Gupta

    2017-07-01

    Full Text Available Paraganglioma is a rare neuroendocrine catecholamine producing tumour in childhood which arises outside the adrenal medulla. We present a 12 year old girl with giant paraganglioma with severe hypertension and end organ damage. Diagnosis was confirmed with 24 h urinary Vanillymandelic Acid (VMA and CT scan. Preoperative blood pressure was controlled with intravenous nitroprusside, and oral prazosin, amlodepine, labetalol and metoprolol. General anaesthesia with epidural analgesia was given. Intra operative blood pressure rise was managed with infusion of nitriglycerine (NTG, esmolol, nitroprusside and propofol.

  16. Giant renal oncocytoma.

    Science.gov (United States)

    Stojanović, Nebojsa; Ignjatovic, Ivan; Kostov, Milos; Mijović, Zaklina; Zivković, Sladjana; Kosević, Branko

    2013-01-01

    Renal onkocytoma is a distinctive benign tumor derived from epithelial cells of the distal renal tubules. These tumors are often clinically asymptomatic, diagnosed accidentally and difficult to distinguish from renal cell carcinoma. We presented a giant renal onkocytoma in a man aged 64, without any signs or symptoms of the urogenital system disorder. The preoperative diagnosis described the tumor mass of the right kidney, size 16 x 14 cm, and indicated a malignant tumor of kidney. The patient underwent radical nephrectomy. The tumor was encapsulated at the intersection with the characteristic central hyaline scar. Microscopically, it was built of uniform polygonal cells with abundant eosinophilic cytoplasm. Immunohystochemiclly, tumor cells were immunoreactive to CK AE1/AE3 and CD 117, but showed negative immunoreactivity to CK 7, RCC marker and Vimentin. Giant renal oncocytomas are rare tumors with benign clinical course. As a rule, they are discovered by accident. Clinical differentiation from malignant tumors of the kidney is not possible. They are treated surgically, mainly by radical nephrectomy. A definitive diagnosis is made only by histopathological examination of tumors using immunohistochemical marker panels.

  17. Giant renal oncocytoma

    Directory of Open Access Journals (Sweden)

    Stojanović Nebojša

    2013-01-01

    Full Text Available Background. Renal onkocytoma is a distinctive benign tumor derived from epithelial cells of the distal renal tubules. These tumors are often clinically asymptomatic, diagnosed accidentally and difficult to distinguish from renal cell carcinoma. Case report. We presented a giant renal onkocytoma in a man aged 64, without any signs or symptoms of the urogenital system disorder. The preoperative diagnosis described the tumor mass of the right kidney, size 16 x 14 cm, and indicated a malignant tumor of kidney. The patient underwent radical nephrectomy. The tumor was encapsulated at the intersection with the characteristic central hyaline scar. Microscopically, it was built of uniform polygonal cells with abundant eosinophilic cytoplasm. Immunohystochemiclly, tumor cells were immunoreactive to CK AE1/AE3 and CD 117, but showed negative immunoreactivity to CK 7, RCC marker and Vimentin. Conclusion. Giant renal oncocytomas are rare tumors with benign clinical course. As a rule, they are discovered by accident. Clinical differentiation from malignant tumors of the kidney is not possible. They are treated surgically, mainly by radical nephrectomy. A definitive diagnosis is made only by histopathological examination of tumors using immunohistochemical marker panels.

  18. Giant omphalocele: current perspectives

    Directory of Open Access Journals (Sweden)

    Mack AJ

    2016-07-01

    Full Text Available Alexander Josef Mack,1 Bjarte Rogdo2 1Department of Pediatric Surgery, 2Pediatric and Neonatal Intensive Care Unit, Children’s Hospital of Eastern Switzerland, St Gallen, Switzerland Abstract: Giant omphalocele (GO is a congenital ventral abdominal wall defect characterized by a large opening with herniated abdominal organs, including liver, loss of abdominal cavity volume, and other associated congenital anomalies. Treatment of patients with GO represents a major challenge for involved caregivers. Despite significant improvements in neonatal intensive and surgical care over the last decades, the condition is still associated with high mortality rates and a high risk of severe morbidity in survivors. The principles of the earliest attempts to treat GO surgically and conservatively are still easily recognized in the main approaches used today. In this review, we discuss the more recent developments in the treatment of GO, including perioperative management and associated morbidities of the condition. Keywords: giant omphalocele, abdominal wall closure, staged repair, delayed repair 

  19. Allometry indicates giant eyes of giant squid are not exceptional.

    Science.gov (United States)

    Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Gamarra, Ashlee R; Lee, Johanna J; Wainwright, Peter C

    2013-02-18

    The eyes of giant and colossal squid are among the largest eyes in the history of life. It was recently proposed that sperm whale predation is the main driver of eye size evolution in giant squid, on the basis of an optical model that suggested optimal performance in detecting large luminous visual targets such as whales in the deep sea. However, it is poorly understood how the eye size of giant and colossal squid compares to that of other aquatic organisms when scaling effects are considered. We performed a large-scale comparative study that included 87 squid species and 237 species of acanthomorph fish. While squid have larger eyes than most acanthomorphs, a comparison of relative eye size among squid suggests that giant and colossal squid do not have unusually large eyes. After revising constants used in a previous model we found that large eyes perform equally well in detecting point targets and large luminous targets in the deep sea. The eyes of giant and colossal squid do not appear exceptionally large when allometric effects are considered. It is probable that the giant eyes of giant squid result from a phylogenetically conserved developmental pattern manifested in very large animals. Whatever the cause of large eyes, they appear to have several advantages for vision in the reduced light of the deep mesopelagic zone.

  20. RE-INFLATED WARM JUPITERS AROUND RED GIANTS

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, Eric D. [Institute for Astronomy, Royal Observatory Edinburgh, University of Edinburgh, Blackford Hill, Edinburgh (United Kingdom); Fortney, Jonathan J. [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States)

    2016-02-10

    Since the discovery of the first transiting hot Jupiters, models have sought to explain the anomalously large radii of highly irradiated gas giants. We now know that the size of hot Jupiter radius anomalies scales strongly with a planet's level of irradiation and numerous models like tidal heating, ohmic dissipation, and thermal tides have since been developed to help explain these inflated radii. In general, however, these models can be grouped into two broad categories: models that directly inflate planetary radii by depositing a fraction of the incident irradiation into the interior and models that simply slow a planet's radiative cooling, allowing it to retain more heat from formation and thereby delay contraction. Here we present a new test to distinguish between these two classes of models. Gas giants orbiting at moderate orbital periods around post-main-sequence stars will experience enormous increases to their irradiation as their host stars move up the sub-giant and red-giant branches. If hot Jupiter inflation works by depositing irradiation into the planet's deep interiors then planetary radii should increase in response to the increased irradiation. This means that otherwise non-inflated gas giants at moderate orbital periods of >10 days can re-inflate as their host stars evolve. Here we explore the circumstances that can lead to the creation of these “re-inflated” gas giants and examine how the existence or absence of such planets can be used to place unique constraints on the physics of the hot Jupiter inflation mechanism. Finally, we explore the prospects for detecting this potentially important undiscovered population of planets.

  1. Natural selection promotes antigenic evolvability

    NARCIS (Netherlands)

    Graves, C.J.; Ros, V.I.D.; Stevenson, B.; Sniegowski, P.D.; Brisson, D.

    2013-01-01

    The hypothesis that evolvability - the capacity to evolve by natural selection - is itself the object of natural selection is highly intriguing but remains controversial due in large part to a paucity of direct experimental evidence. The antigenic variation mechanisms of microbial pathogens provide

  2. Disgust: Evolved function and structure

    NARCIS (Netherlands)

    Tybur, J.M.; Lieberman, D.; Kurzban, R.; DeScioli, P.

    2013-01-01

    Interest in and research on disgust has surged over the past few decades. The field, however, still lacks a coherent theoretical framework for understanding the evolved function or functions of disgust. Here we present such a framework, emphasizing 2 levels of analysis: that of evolved function and

  3. Orbital Decay in Binaries with Evolved Stars

    Science.gov (United States)

    Sun, Meng; Arras, Phil; Weinberg, Nevin N.; Troup, Nicholas; Majewski, Steven R.

    2018-01-01

    Two mechanisms are often invoked to explain tidal friction in binary systems. The ``dynamical tide” is the resonant excitation of internal gravity waves by the tide, and their subsequent damping by nonlinear fluid processes or thermal diffusion. The ``equilibrium tide” refers to non-resonant excitation of fluid motion in the star’s convection zone, with damping by interaction with the turbulent eddies. There have been numerous studies of these processes in main sequence stars, but less so on the subgiant and red giant branches. Motivated by the newly discovered close binary systems in the Apache Point Observatory Galactic Evolution Experiment (APOGEE-1), we have performed calculations of both the dynamical and equilibrium tide processes for stars over a range of mass as the star’s cease core hydrogen burning and evolve to shell burning. Even for stars which had a radiative core on the main sequence, the dynamical tide may have very large amplitude in the newly radiative core in post-main sequence, giving rise to wave breaking. The resulting large dynamical tide dissipation rate is compared to the equilibrium tide, and the range of secondary masses and orbital periods over which rapid orbital decay may occur will be discussed, as well as applications to close APOGEE binaries.

  4. On to the Ice Giants

    Science.gov (United States)

    Reh, Kim; Hofstdater, Mark; Simon, Amy; Elliott, John

    2017-04-01

    Voyager 2 mission flew by Uranus in 1986 and Neptune in 1989 resulting in stunning remote observations not previously accessible from the ground. There have been no follow-up space flight missions to examine ice giants and, as a result there are significant gaps in our understanding of planetary formation and evolution. This gap not only affects our understanding of our own solar system but also our understanding of exoplanets; the majority of planets discovered around other stars are thought to be ice giants. Ice Giants are likely to be far more abundant in our galaxy than previously thought. The U.S. 2011 Planetary Science Decadal Survey committee recognized the importance of Uranus and Neptune, and prioritized the exploration of the Ice Giants. Following from this, NASA and ESA have recently completed a study of candidate missions to Uranus and Neptune, the so-called ice giant planets. The intent was to examine what could be accomplished within the budget realities of the predictable future. This "Pre-Decadal Study," focused on opportunities for missions launching in the 2020's and early 2030's. This paper presents results from the Ice Giants study (science, architectures and technologies) and concludes that compelling and affordable missions to the Ice Giants are within our reach.

  5. Evolving virtual creatures and catapults.

    Science.gov (United States)

    Chaumont, Nicolas; Egli, Richard; Adami, Christoph

    2007-01-01

    We present a system that can evolve the morphology and the controller of virtual walking and block-throwing creatures (catapults) using a genetic algorithm. The system is based on Sims' work, implemented as a flexible platform with an off-the-shelf dynamics engine. Experiments aimed at evolving Sims-type walkers resulted in the emergence of various realistic gaits while using fairly simple objective functions. Due to the flexibility of the system, drastically different morphologies and functions evolved with only minor modifications to the system and objective function. For example, various throwing techniques evolved when selecting for catapults that propel a block as far as possible. Among the strategies and morphologies evolved, we find the drop-kick strategy, as well as the systematic invention of the principle behind the wheel, when allowing mutations to the projectile.

  6. Preoperative progressive pneumoperitoneum for giant inguinal hernias

    OpenAIRE

    Piskin, Turgut; Aydin, Cemalettin; Barut, Bora; Dirican, Abuzer; Kayaalp, Cuneyt

    2010-01-01

    Reduction of giant hernia contents into the abdominal cavity may cause intraoperative and postoperative problems such as abdominal compartment syndrome. Preoperative progressive pneumoperitoneum expands the abdominal cavity, increases the patient?s tolerability to operation, and can diminish intraoperative and postoperative complications. Preoperative progressive pneumoperitoneum is recommended for giant ventral hernias, but rarely for giant inguinal hernias. We present two giant inguinal her...

  7. No surviving evolved companions of the progenitor of SN 1006.

    Science.gov (United States)

    González Hernández, Jonay I; Ruiz-Lapuente, Pilar; Tabernero, Hugo M; Montes, David; Canal, Ramon; Méndez, Javier; Bedin, Luigi R

    2012-09-27

    Type Ia supernovae are thought to occur when a white dwarf made of carbon and oxygen accretes sufficient mass to trigger a thermonuclear explosion. The accretion could be slow, from an unevolved (main-sequence) or evolved (subgiant or giant) star (the single-degenerate channel), or rapid, as the primary star breaks up a smaller orbiting white dwarf (the double-degenerate channel). A companion star will survive the explosion only in the single-degenerate channel. Both channels might contribute to the production of type Ia supernovae, but the relative proportions of their contributions remain a fundamental puzzle in astronomy. Previous searches for remnant companions have revealed one possible case for SN 1572 (refs 8, 9), although that has been questioned. More recently, observations have restricted surviving companions to be small, main-sequence stars, ruling out giant companions but still allowing the single-degenerate channel. Here we report the results of a search for surviving companions of the progenitor of SN 1006 (ref. 14). None of the stars within 4 arc minutes of the apparent site of the explosion is associated with the supernova remnant, and we can firmly exclude all giant and subgiant stars from being companions of the progenitor. In combination with previous results, our findings indicate that fewer than 20 per cent of type Ia supernovae occur through the single-degenerate channel.

  8. Surface Compositions of Red Giant Stars in Globular Clusters

    Science.gov (United States)

    Cheng, Eric; Lau, Marie; Smith, Graeme; Chen, Brian

    2018-01-01

    Globular clusters (GCs) are excellent “laboratories” to study the formation and evolution of our galaxy. In order to understand, more specifically, the chemical compositions and stellar evolution of the stars in GCs, we ask whether or not deep internal mixing occurs in red giants or if in fact the compositions come from the primordial interstellar medium or previous generations of stars. It has been discovered that as a star evolves up the red giant branch, the surface carbon abundance decreases, which is evidence of deep internal mixing. We questioned whether these processes also affect O or Na abundance as a star evolves. We collected measurement data of red giants from GCs out of academic journals and sorted the data into catalogs. Then, we plotted the catalogs into figures, comparing surface O and Na each with stellar luminosity. Statistical tests were ran to quantify the amount of correlation between the variables. Out of 27 GCs, we concluded that eight show a positive correlation between Na and luminosity, and two show a negative correlation between O and luminosity. Properties of GCs were compared to determine if chemical distribution in stars depends on GCs as the self-enrichment scenario suggests. We created histograms of sodium distribution to test for bimodality to examine if there are separate trends in each GC. In six GCs, two different sequences of red giants appear for Na versus luminosity, suggesting evidence that the depth of mixing may differ among each red giant in a GC. This study has provided new evidence that the changing chemical abundances on the surfaces of red giants can be due to stellar evolutionary effects and deep internal mixing, which may not necessarily depend on the GC and may differ in depth among each red giant. Through this study, we learn more about stellar evolution which will eventually help us understand the origins of our universe. Most of this work was carried out by high school students working under the auspices of

  9. Recurrent giant juvenile fibroadenoma

    Directory of Open Access Journals (Sweden)

    Kathryn S. King

    2017-11-01

    Full Text Available Breast masses in children, though rare, present a difficult clinical challenge as they can represent a wide variety of entities from benign fibroadenomas to phyllodes tumors. Rapidly growing or recurrent masses can be particularly concerning to patients, families and physicians alike. Clinical examination and conventional imaging modalities are not efficacious in distinguishing between different tumor types and surgical excision is often recommended for both final diagnosis and for treatment of large or rapidly growing masses. While surgical excision can result in significant long-term deformity of the breast there are some surgical techniques that can be used to limit deformity and/or aid in future reconstruction. Here we present a case of recurrent giant juvenile fibroadenoma with a review of the clinical presentation, diagnostic tools and treatment options.

  10. Giant Congenital Melanocytic Nevus

    DEFF Research Database (Denmark)

    Rasmussen, Bo Sonnich; Henriksen, Trine Foged; Kølle, Stig-Frederik Trojahn

    2015-01-01

    % versus 44% required unplanned additional surgery, respectively. Complications were noted in 25% and 67% of the patients, respectively. Cosmetic result was satisfying in 76% of patients without difference between the groups. No malignant transformation was found during a mean follow-up of 11 years......Giant congenital melanocytic nevi (GCMN) occur in 1:20,000 livebirths and are associated with increased risk of malignant transformation. The treatment of GCMN from 1981 to 2010 in a tertiary referral center was reviewed evaluating the modalities used, cosmetic results, associated complications......, and malignant transformation. Of 35 patients, 25 underwent surgery. Curettage was most frequently used (64%) followed by excision and tissue expansion (20%). Six percent of the patients treated with curettage, and 78% of the patients who received excision surgery required more than 1 planned procedure, and 25...

  11. Giant Planet Formation and Migration

    Science.gov (United States)

    Paardekooper, Sijme-Jan; Johansen, Anders

    2018-02-01

    Planets form in circumstellar discs around young stars. Starting with sub-micron sized dust particles, giant planet formation is all about growing 14 orders of magnitude in size. It has become increasingly clear over the past decades that during all stages of giant planet formation, the building blocks are extremely mobile and can change their semimajor axis by substantial amounts. In this chapter, we aim to give a basic overview of the physical processes thought to govern giant planet formation and migration, and to highlight possible links to water delivery.

  12. Giant Hedge-Hogs: Spikes on Giant Gravitons

    Energy Technology Data Exchange (ETDEWEB)

    Sadri, D

    2004-01-28

    We consider giant gravitons on the maximally supersymmetric plane-wave background of type IIB string theory. Fixing the light-cone gauge, we work out the low energy effective light-cone Hamiltonian of the three-sphere giant graviton. At first order, this is a U(1) gauge theory on R x S{sup 3}. We place sources in this effective gauge theory. Although non-vanishing net electric charge configurations are disallowed by Gauss' law, electric dipoles can be formed. From the string theory point of view these dipoles can be understood as open strings piercing the three-sphere, generalizing the usual BIons to the giant gravitons, BIGGons. Our results can be used to give a two dimensional (worldsheet) description of giant gravitons, similar to Polchinski's description for the usual D-branes, in agreement with the discussions of hep-th/0204196.

  13. Giant viruses: The difficult breaking of multiple epistemological barriers.

    Science.gov (United States)

    Claverie, Jean-Michel; Abergel, Chantal

    2016-10-01

    The discovery of the first "giant virus", Mimivirus, in 2003 could solely have been that of an exceptional freak, a blind alley of evolution as occasionally encountered in biology, albeit without conceptual significance. On the contrary, once broken this epistemological barrier, additional unrelated families of giant viruses such as the Pandoraviruses, the Pithoviruses and most recently Mollivirus, were quickly unraveled, suggesting that an entire chapter of microbiology had been ignored since Pasteur and Ivanovski. In this article, we examine to what extent the giant viruses challenge previous definitions of viruses, the diversity of forms they could take, and how they might have evolved from extinct ancestral cellular lineages. Inspired by the epistemology of Gaston Bachelard, we will also suggest the reasons for which giant viruses laid hidden in plain sight for more than a century. Finally, we propose a new definition for "viruses" that paradoxically emphasize the fact that they do not encode a single universally shared macromolecule or biochemical function. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. [Giant cell glioblastoma. Case report].

    Science.gov (United States)

    Alvarez-Betancourt, Leonardo; López-Ortega, Salvador; Caldera-Duarte, Agustín

    2004-01-01

    Glioblastomas (World Health Organization, (WHO), grade IV) are the most frequent and malignant neoplasms of the human nervous system. Giant cells glioblastomas, a subtype of these, account for less than 1% of all brain toumors and up to 5% of glioblastomas. We present the case of a female who was diagnosed and treated for a right intra and paraventricular giant cell glioblastoma. We enfatize the importance of histological features of this toumor related to its prognosis.

  15. When did oxygenic photosynthesis evolve?

    National Research Council Canada - National Science Library

    Roger Buick

    2008-01-01

    ...2.4 Ga ago, but when the photosynthetic oxygen production began is debatable. However, geological and geochemical evidence from older sedimentary rocks indicates that oxygenic photosynthesis evolved well before this oxygenation event...

  16. Marshal: Maintaining Evolving Models Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SIFT proposes to design and develop the Marshal system, a mixed-initiative tool for maintaining task models over the course of evolving missions. Marshal-enabled...

  17. Natural selection promotes antigenic evolvability.

    Science.gov (United States)

    Graves, Christopher J; Ros, Vera I D; Stevenson, Brian; Sniegowski, Paul D; Brisson, Dustin

    2013-01-01

    The hypothesis that evolvability - the capacity to evolve by natural selection - is itself the object of natural selection is highly intriguing but remains controversial due in large part to a paucity of direct experimental evidence. The antigenic variation mechanisms of microbial pathogens provide an experimentally tractable system to test whether natural selection has favored mechanisms that increase evolvability. Many antigenic variation systems consist of paralogous unexpressed 'cassettes' that recombine into an expression site to rapidly alter the expressed protein. Importantly, the magnitude of antigenic change is a function of the genetic diversity among the unexpressed cassettes. Thus, evidence that selection favors among-cassette diversity is direct evidence that natural selection promotes antigenic evolvability. We used the Lyme disease bacterium, Borrelia burgdorferi, as a model to test the prediction that natural selection favors amino acid diversity among unexpressed vls cassettes and thereby promotes evolvability in a primary surface antigen, VlsE. The hypothesis that diversity among vls cassettes is favored by natural selection was supported in each B. burgdorferi strain analyzed using both classical (dN/dS ratios) and Bayesian population genetic analyses of genetic sequence data. This hypothesis was also supported by the conservation of highly mutable tandem-repeat structures across B. burgdorferi strains despite a near complete absence of sequence conservation. Diversification among vls cassettes due to natural selection and mutable repeat structures promotes long-term antigenic evolvability of VlsE. These findings provide a direct demonstration that molecular mechanisms that enhance evolvability of surface antigens are an evolutionary adaptation. The molecular evolutionary processes identified here can serve as a model for the evolution of antigenic evolvability in many pathogens which utilize similar strategies to establish chronic infections.

  18. Natural selection promotes antigenic evolvability.

    Directory of Open Access Journals (Sweden)

    Christopher J Graves

    Full Text Available The hypothesis that evolvability - the capacity to evolve by natural selection - is itself the object of natural selection is highly intriguing but remains controversial due in large part to a paucity of direct experimental evidence. The antigenic variation mechanisms of microbial pathogens provide an experimentally tractable system to test whether natural selection has favored mechanisms that increase evolvability. Many antigenic variation systems consist of paralogous unexpressed 'cassettes' that recombine into an expression site to rapidly alter the expressed protein. Importantly, the magnitude of antigenic change is a function of the genetic diversity among the unexpressed cassettes. Thus, evidence that selection favors among-cassette diversity is direct evidence that natural selection promotes antigenic evolvability. We used the Lyme disease bacterium, Borrelia burgdorferi, as a model to test the prediction that natural selection favors amino acid diversity among unexpressed vls cassettes and thereby promotes evolvability in a primary surface antigen, VlsE. The hypothesis that diversity among vls cassettes is favored by natural selection was supported in each B. burgdorferi strain analyzed using both classical (dN/dS ratios and Bayesian population genetic analyses of genetic sequence data. This hypothesis was also supported by the conservation of highly mutable tandem-repeat structures across B. burgdorferi strains despite a near complete absence of sequence conservation. Diversification among vls cassettes due to natural selection and mutable repeat structures promotes long-term antigenic evolvability of VlsE. These findings provide a direct demonstration that molecular mechanisms that enhance evolvability of surface antigens are an evolutionary adaptation. The molecular evolutionary processes identified here can serve as a model for the evolution of antigenic evolvability in many pathogens which utilize similar strategies to establish

  19. Bringing Low the Giants

    CERN Multimedia

    2001-01-01

    Their work goes on unseen, because they a hundred metres beneath your feet. But while the race against the clock to build the LHC has begun on the surface, teams underground are feverishly engaged to dismantle LEP and its experiments. Four months after the start of dismantling, the technical coordinators of the different experiments discuss the progress of work. Little men attack the giant ALEPH. The barrel and its two endcaps have been removed to the end of the cavern and stripped of their cables. The breaking up of the detector can now begin. At ALEPH, counting rooms removed all in one go Jean-Paul Fabre, technical coordinator at ALEPH:'After making safe the structure, the first step was to remove the wiring and cables. Some 210 cubic metres were brought out. Then the counting rooms all round the detector were taken out. They were brought up from the cavern all in one go, up through the shaft, which is 10 metres wide and 150 metres deep. They made it with 15 centimetres to spare. They have been emptied of...

  20. Giant high occipital encephalocele

    Directory of Open Access Journals (Sweden)

    Agrawal Amit

    2016-03-01

    Full Text Available Encephaloceles are rare embryological mesenchymal developmental anomalies resulting from inappropriate ossification in skull through with herniation of intracranial contents of the sac. Encephaloceles are classified based on location of the osseous defect and contents of sac. Convexity encephalocele with osseous defect in occipital bone is called occipital encephalocele. Giant occipital encephaloceles can be sometimes larger than the size of baby skull itself and they pose a great surgical challenge. Occipital encephaloceles (OE are further classified as high OE when defect is only in occipital bone above the foramen magnum, low OE when involving occipital bone and foramen magnum and occipito-cervical when there involvement of occipital bone, foramen magnum and posterior upper neural arches. Chiari III malformation can be associated with high or low occipital encephaloceles. Pre-operatively, it is essential to know the size of the sac, contents of the sac, relation to the adjacent structures, presence or absence of venous sinuses/vascular structures and osseous defect size. Sometimes it becomes imperative to perform both CT and MRI for the necessary information. Volume rendered CT images can depict the relation of osseous defect to foramen magnum and provide information about upper neural arches which is necessary in classifying these lesions.

  1. Recurrent renal giant leiomyosarcoma.

    Science.gov (United States)

    Öziş, Salih Erpulat; Gülpınar, Kamil; Şahlı, Zafer; Konak, Baha Burak; Keskin, Mete; Özdemir, Süleyman; Ataoğlu, Ömür

    2016-01-01

    Primary renal leiomyosarcomas are rare, aggressive tumors. They constitute 1-2% of adult malignant renal tumors. Although leiomyosarcomas are the most common histological type (50-60%) of renal sarcomas, information on renal leiomyosarcoma is limited. Local or systemic recurrences are common. The radiological appearance of renal leiomyosarcomas is not specific, therefore renal leiomyosarcoma cannot be distinguished from renal cell carcinoma by imaging methods in all patients. A 74-year-old female patient presented to our clinic complaining of a palpable mass on the right side of her abdomen in November 2012. The abdominal magnetic resonance imaging revealed a mass, 25 × 24 × 23 cm in size. Her past medical history revealed that she has undergone right radical nephrectomy in 2007, due to a 11 × 12 × 13 cm renal mass that was then reported as renal cell carcinoma on abdominal magnetic resonance imaging, but the pathological diagnosis was low-grade renal leiomyosarcoma. The most recent follow-up of the patient was in 2011, with no signs of local recurrence or distant metastases within this four-year period. The patient underwent laparotomy on November 2012, and a 35 cm retroperitoneal mass was excised. The pathological examination of the mass was reported as high-grade leiomyosarcoma. The formation of this giant retroperitoneal mass in 1 year can be explained by the transformation of the lesion's pathology from low-grade to a high-grade tumor.

  2. Giant ovarian cyst

    Directory of Open Access Journals (Sweden)

    V. M. Santos

    2015-09-01

    Full Text Available We read the exceedingly rare case study recently described by Hota et al. about giant ovarian cyst in term pregnancy1. The patient was a 25-year-old woman undergoing therapy for hypothyroidism, with history of three previous deliveries (P1L1A1. USG of abdomen and pelvis was normal with respect to gestational age in the second trimester, and ovarian cyst was not seen. However, the USG of control done on the third trimester revealed a left ovarian cyst (21x18 cm, with normal obstetric features. The weight of removed cyst of 29x20 cm was 4.9 kg, and the histopathology diagnosis was ovarian mucinous cystadenoma1. The authors emphasized the rarity of concomitat pregnancy and ovarian cyst, and 15% of these mucinous cysts are malignant1. Huge ovarian cysts are more often benign, and less frequently they are diagnosed in association with normal pregnancies1. Major concerns in this setting should be the early diagnosis, close follow-up of the cyst growing, and appropriate intervention1. Interestingly, in the case herein commented the ovarian cyst was not detected by USG in the first two trimesters of pregnancy. 

  3. A rare case of giant cutaneous leiomyosarcoma: A case report

    Directory of Open Access Journals (Sweden)

    Mehdi Iskandarli

    2015-09-01

    Full Text Available Leiomyosarcoma (LMS commonly evolving from smooth muscles of visceral organs like uterus, gastrointestinal system and has a worse prognosis due to its metastatic potential. LMS derived from smooth muscles of the skin, named superficial LMS, usually indolent and has a better prognosis. Especially LMS derived from pilar muscles usually restricted to the dermis and rarely metastasise. However, LMS developed from smooth muscles of subcutis, behaves more agressively and metastasing more oftenly. Here we report a case, in which patient consequently amputated and received chemotherapy due to giant superficial LMS on lower extremity which invaded underlying tissues like bone, tendons and joint and metastasized to the lung.

  4. Rotation of Giant Stars

    Science.gov (United States)

    Kissin, Yevgeni; Thompson, Christopher

    2015-07-01

    The internal rotation of post-main sequence stars is investigated, in response to the convective pumping of angular momentum toward the stellar core, combined with a tight magnetic coupling between core and envelope. The spin evolution is calculated using model stars of initial mass 1, 1.5, and 5 {M}⊙ , taking into account mass loss on the giant branches. We also include the deposition of orbital angular momentum from a sub-stellar companion, as influenced by tidal drag along with the excitation of orbital eccentricity by a fluctuating gravitational quadrupole moment. A range of angular velocity profiles {{Ω }}(r) is considered in the envelope, extending from solid rotation to constant specific angular momentum. We focus on the backreaction of the Coriolis force, and the threshold for dynamo action in the inner envelope. Quantitative agreement with measurements of core rotation in subgiants and post-He core flash stars by Kepler is obtained with a two-layer angular velocity profile: uniform specific angular momentum where the Coriolis parameter {Co}\\equiv {{Ω }}{τ }{con}≲ 1 (here {τ }{con} is the convective time), and {{Ω }}(r)\\propto {r}-1 where {Co}≳ 1. The inner profile is interpreted in terms of a balance between the Coriolis force and angular pressure gradients driven by radially extended convective plumes. Inward angular momentum pumping reduces the surface rotation of subgiants, and the need for a rejuvenated magnetic wind torque. The co-evolution of internal magnetic fields and rotation is considered in Kissin & Thompson, along with the breaking of the rotational coupling between core and envelope due to heavy mass loss.

  5. Giant Magellan Telescope: overview

    Science.gov (United States)

    Johns, Matt; McCarthy, Patrick; Raybould, Keith; Bouchez, Antonin; Farahani, Arash; Filgueira, Jose; Jacoby, George; Shectman, Steve; Sheehan, Michael

    2012-09-01

    The Giant Magellan Telescope (GMT) is a 25-meter optical/infrared extremely large telescope that is being built by an international consortium of universities and research institutions. It will be located at the Las Campanas Observatory, Chile. The GMT primary mirror consists of seven 8.4-m borosilicate honeycomb mirror segments made at the Steward Observatory Mirror Lab (SOML). Six identical off-axis segments and one on-axis segment are arranged on a single nearly-paraboloidal parent surface having an overall focal ratio of f/0.7. The fabrication, testing and verification procedures required to produce the closely-matched off-axis mirror segments were developed during the production of the first mirror. Production of the second and third off-axis segments is underway. GMT incorporates a seven-segment Gregorian adaptive secondary to implement three modes of adaptive-optics operation: natural-guide star AO, laser-tomography AO, and ground-layer AO. A wide-field corrector/ADC is available for use in seeing-limited mode over a 20-arcmin diameter field of view. Up to seven instruments can be mounted simultaneously on the telescope in a large Gregorian Instrument Rotator. Conceptual design studies were completed for six AO and seeing-limited instruments, plus a multi-object fiber feed, and a roadmap for phased deployment of the GMT instrument suite is being developed. The partner institutions have made firm commitments for approximately 45% of the funds required to build the telescope. Project Office efforts are currently focused on advancing the telescope and enclosure design in preparation for subsystem- and system-level preliminary design reviews which are scheduled to be completed in the first half of 2013.

  6. Leonardo Da Vinci’s giant crossbow

    CERN Document Server

    Landrus, Matt

    2010-01-01

    Leonardo's Giant Crossbow is one of his least understood drawings. This fascinating book offers the first in-depth account of its likely purpose and its highly resolved design. It presents original research and new discoveries about the giant crossbow.

  7. Imaging of giant pituitary adenomas

    Energy Technology Data Exchange (ETDEWEB)

    Majos, C.; Coll, S.; Aguilera, C.; Pons, L.C. [Bellvitge Univ., Barcelona (Spain). Inst. de Diagnostice per la Imatge; Acebes, J.J. [Department of Neurosurgery, Ciutat Sanitaria i Universitaria de Bellvitge, L`Hospitalet de Llobregat, Barcelona (Spain)

    1998-10-01

    We present five proven giant pituitary adenomas studied by CT and MRI, and review the clinical and imaging findings. Our aim was to examine the radiologic appearances and to search for criteria useful in distinguishing these tumors from other sellar and suprasellar tumours, mainly craniopharyngioma. The main differences from small adenomas were high prevalence of macrocysts, a more invasive behaviour and a clinical picture dominated by mass effect rather than endocrine disturbance. Factors supporting the diagnosis of pituitary adenoma in a giant intra- and suprasellar mass include: infrasellar extension, absence of calcification and presence of low-signal cysts on T1-weighted images. (orig.) (orig.) With 4 figs., 2 tabs., 9 refs.

  8. Awakening a sleeping coal giant

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, B.

    2007-08-15

    Botswana, a southern African country that in the 1980s could not economically land a tonne of coal at the closest export terminal and even today mines no more than 1 million tpa, is to increase production to beyond 30 million tpa. A first ever coal conference in Gaborone called it the awakening of a coal giant. The alarm call for the coal giant is the realisation that without more generating capacity than its power utility Eskom can itself build in time, South Africa will in four to five years face a severe shortage of power. 1 ref., 5 figs., 2 tabs.

  9. Cabergoline Treatment in Invasive Giant Prolactinoma

    OpenAIRE

    Sadeem Alsubaie; Almalki, Mussa H

    2014-01-01

    Patients with invasive giant prolactinoma suffer from a constellation of symptoms including headache, blurred vision, lethargy, and sexual dysfunction. Cabergoline, a potent dopamine agonist, is a known medication prescribed for the treatment of invasive giant prolactinoma. Here, we report a case of invasive giant prolactinoma in a 52-year-old Saudi male with dramatic response to cabergoline treatment clinically, biochemically, and radiologically.

  10. Nursery of Giants

    Science.gov (United States)

    2004-01-01

    Hidden behind a shroud of dust in the constellation Cygnus is a stellar nursery called DR21, which is giving birth to some of the most massive stars in our galaxy. Visible light images reveal no trace of this interstellar cauldron because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion). New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud. This image is a large-scale mosaic assembled from individual photographs obtained with the InfraRed Array Camera (IRAC) aboard Spitzer. The image covers an area about two times that of a full moon. The mosaic is a composite of images obtained at mid-infrared wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange) and 8 microns (red). The brightest infrared cloud near the top center corresponds to DR21, which presumably contains a cluster of newly forming stars at a distance of 10,000 light-years. Protruding out from DR21 toward the bottom left of the image is a gaseous outflow (green), containing both carbon monoxide and molecular hydrogen. Data from the Spitzer spectrograph, which breaks light into its constituent individual wavelengths, indicate the presence of hot steam formed as the outflow heats the surrounding molecular gas. Outflows are physical signatures of processes that create supersonic beams, or jets, of gas. They are usually accompanied by discs of material around the new star, which likely contain the materials from which future planetary systems are formed. Additional newborn stars, depicted in green, can be seen surrounding the DR21 region

  11. Charting the Giants

    Science.gov (United States)

    2004-06-01

    zero expansion asymptotically after an infinite time and has a flat geometry). All three observational tests by means of supernovae (green), the cosmic microwave background (blue) and galaxy clusters converge at a Universe around Ωm ~ 0.3 and ΩΛ ~ 0.7. The dark red region for the galaxy cluster determination corresponds to 95% certainty (2-sigma statistical deviation) when assuming good knowledge of all other cosmological parameters, and the light red region assumes a minimum knowledge. For the supernovae and WMAP results, the inner and outer regions corespond to 68% (1-sigma) and 95% certainty, respectively. References: Schuecker et al. 2003, A&A, 398, 867 (REFLEX); Tonry et al. 2003, ApJ, 594, 1 (supernovae); Riess et al. 2004, ApJ, 607, 665 (supernovae) Galaxy clusters are far from being evenly distributed in the Universe. Instead, they tend to conglomerate into even larger structures, "super-clusters". Thus, from stars which gather in galaxies, galaxies which congregate in clusters and clusters tying together in super-clusters, the Universe shows structuring on all scales, from the smallest to the largest ones. This is a relict of the very early (formation) epoch of the Universe, the so-called "inflationary" period. At that time, only a minuscule fraction of one second after the Big Bang, the tiny density fluctuations were amplified and over the eons, they gave birth to the much larger structures. Because of the link between the first fluctuations and the giant structures now observed, the unique REFLEX catalogue - the largest of its kind - allows astronomers to put considerable constraints on the content of the Universe, and in particular on the amount of dark matter that is believed to pervade it. Rather interestingly, these constraints are totally independent from all other methods so far used to assert the existence of dark matter, such as the study of very distant supernovae (see e.g. ESO PR 21/98) or the analysis of the Cosmic Microwave background (e

  12. Giant lipomas of the hand

    Directory of Open Access Journals (Sweden)

    Gokce Yildiran

    2015-04-01

    Conclusion: Giant lipomas of the hand are very rare and may cause compressions and other complications. Thus, they require a careful preoperative evaluation in order to make a proper differential diagnosis. [Hand Microsurg 2015; 4(1.000: 8-11

  13. Unusual Giant Prostatic Urethral Calculus

    African Journals Online (AJOL)

    2010-06-29

    Jun 29, 2010 ... associated with benign prostatic hyperplasia, and prostatic cancer.[1] Primary prostatic urethral calculi are ... Giant vesico-prostatic urethral calculus is uncommon. Urethral stones rarely form primarily in the urethra, ... Prostatic calculi associated with hypertrophy of the gland. Group III. Prostatic calculi that ...

  14. Michigan has a sleeping giant

    CERN Multimedia

    Brock, Raymond; Nichols, Sue

    2007-01-01

    "That giant is 750 miles of fiber optic cable that lassoes its three biggest research universities and Van Andel Institute to the future. Its mission: to uncover the nature of the Big Bang by connecton U.S. physicists to their huge experiment ATLAS in Geneva.." (4 pages)

  15. A Giant or a Dwarf?

    DEFF Research Database (Denmark)

    Schmid, Herman

    2005-01-01

    EU may appear to be a giant when it can act on behalf of a united Europe, but usually it is hampered by conflicting member state interests. The EU economic and administrative resources for foreign and trade policy are quite small (on level with one of its major member states) and the hopes in man...

  16. The Evolving Resource Metadata Infrastructure

    Science.gov (United States)

    Biemesderfer, Chris

    The search and discovery mechanisms that will facilitate and simplify systematic research on the Internet depend on systematic classifications of resources, as well as on standardized access to such metadata. The principles and technologies that will make this possible are evolving in the work of the Internet Engineering Task Force and the digital library initiatives, among others. The desired outcome is a set of standards, tools, and practices that permits both cataloging and retrieval to be comprehensive and efficient.

  17. Giant hydronephrosis mimicking progressive malignancy

    Directory of Open Access Journals (Sweden)

    Heidenreich Axel

    2003-10-01

    Full Text Available Abstract Background Cases of giant hydronephroses are rare and usually contain no more than 1–2 litres of fluid in the collecting system. We report a remarkable case of giant hydronephrosis mimicking a progressive malignant abdominal tumour. Case presentation A 78-year-old cachectic woman presented with an enormous abdominal tumour, which, according to the patient, had slowly increased in diameter. Medical history was unremarkable except for a hysterectomy >30 years before. A CT scan revealed a giant cystic tumour filling almost the entire abdominal cavity. It was analysed by two independent radiologists who suspected a tumour originating from the right kidney and additionally a cystic ovarian neoplasm. Subsequently, a diagnostic and therapeutic laparotomy was performed: the tumour presented as a cystic, 35 × 30 × 25 cm expansive structure adhesive to adjacent organs without definite signs of invasive growth. The right renal hilar vessels could finally be identified at its basis. After extirpation another tumourous structure emerged in the pelvis originating from the genital organs and was also resected. The histopathological examination revealed a >15 kg hydronephrotic right kidney, lacking hardly any residual renal cortex parenchyma. The second specimen was identified as an ovary with regressive changes and a large partially calcified cyst. There was no evidence of malignant growth. Conclusion Although both clinical symptoms and the enormous size of the tumour indicated malignant growth, it turned out to be a giant hydronephrosis. Presumably, a chronic obstruction of the distal ureter had caused this extraordinary hydronephrosis. As demonstrated in our case, an accurate diagnosis of giant hydronephrosis remains challenging due to the atrophy of the renal parenchyma associated with chronic obstruction. Therefore, any abdominal cystic mass even in the absence of other evident pathologies should include the differential diagnosis of a

  18. Ranking in evolving complex networks

    Science.gov (United States)

    Liao, Hao; Mariani, Manuel Sebastian; Medo, Matúš; Zhang, Yi-Cheng; Zhou, Ming-Yang

    2017-05-01

    Complex networks have emerged as a simple yet powerful framework to represent and analyze a wide range of complex systems. The problem of ranking the nodes and the edges in complex networks is critical for a broad range of real-world problems because it affects how we access online information and products, how success and talent are evaluated in human activities, and how scarce resources are allocated by companies and policymakers, among others. This calls for a deep understanding of how existing ranking algorithms perform, and which are their possible biases that may impair their effectiveness. Many popular ranking algorithms (such as Google's PageRank) are static in nature and, as a consequence, they exhibit important shortcomings when applied to real networks that rapidly evolve in time. At the same time, recent advances in the understanding and modeling of evolving networks have enabled the development of a wide and diverse range of ranking algorithms that take the temporal dimension into account. The aim of this review is to survey the existing ranking algorithms, both static and time-aware, and their applications to evolving networks. We emphasize both the impact of network evolution on well-established static algorithms and the benefits from including the temporal dimension for tasks such as prediction of network traffic, prediction of future links, and identification of significant nodes.

  19. Giant osteoma of the ethmoidal sinus

    Directory of Open Access Journals (Sweden)

    Marambaia, Otavio

    2009-06-01

    Full Text Available Introduction: The osteomas are osseous lesions with slow and asymptomatic growth that most of the times is a finding in radiological exams requested for other reason. It's the most common benign neoplasm of the paranasal sinuses. The osteomas are located mainly in the frontal sinus (57% to 80%, followed by the ethmoidal sinuses (20%, maxillary sinuses and rarely in the sphenoid sinus. It has a discreet predominance in the male sex 1.5 and its incidence is higher in the 3rd and 4th decades of life. The treatment is surgical no matter the size. Objective: To describe a case of giant osteoma of the ethmoidal sinus including a brief literature review. Case Report: JDA, male, 33 years old, presented with a right constant nasal obstruction for 01 year. Upon exam, he presented with facial asymmetry with lateralization of the right ocular globe. The computed tomography of the paranasal sinuses showed a lesion with density of soft parts occupying partially the right nasal cavity, ethmoid sinus and right maxillary. The patient was submitted to surgery with full exeresis of the lesion. The anatomopathological exam confirmed osteoma. The patient evolved without evidences of the lesion recurrence. Final Comments: The osteomas in the ethmoidal sinus, irrespectively of the size and due to the risk of complications, must be operated.

  20. Numerical aspects of giant impact simulations

    Science.gov (United States)

    Reinhardt, Christian; Stadel, Joachim

    2017-06-01

    In this paper, we present solutions to three short comings of smoothed particles hydrodynamics (SPH) encountered in previous work when applying it to giant impacts. First we introduce a novel method to obtain accurate SPH representations of a planet's equilibrium initial conditions based on equal area tessellations of the sphere. This allows one to imprint an arbitrary density and internal energy profile with very low noise which substantially reduces computation because these models require no relaxation prior to use. As a consequence one can significantly increase the resolution and more flexibly change the initial bodies to explore larger parts of the impact parameter space in simulations. The second issue addressed is the proper treatment of the matter/vacuum boundary at a planet's surface with a modified SPH density estimator that properly calculates the density stabilizing the models and avoiding an artificially low-density atmosphere prior to impact. Further we present a novel SPH scheme that simultaneously conserves both energy and entropy for an arbitrary equation of state. This prevents loss of entropy during the simulation and further assures that the material does not evolve into unphysical states. Application of these modifications to impact simulations for different resolutions up to 6.4 × 106 particles show a general agreement with prior result. However, we observe resolution-dependent differences in the evolution and composition of post-collision ejecta. This strongly suggests that the use of more sophisticated equations of state also demands a large number of particles in such simulations.

  1. The evolvability of programmable hardware

    Science.gov (United States)

    Raman, Karthik; Wagner, Andreas

    2011-01-01

    In biological systems, individual phenotypes are typically adopted by multiple genotypes. Examples include protein structure phenotypes, where each structure can be adopted by a myriad individual amino acid sequence genotypes. These genotypes form vast connected ‘neutral networks’ in genotype space. The size of such neutral networks endows biological systems not only with robustness to genetic change, but also with the ability to evolve a vast number of novel phenotypes that occur near any one neutral network. Whether technological systems can be designed to have similar properties is poorly understood. Here we ask this question for a class of programmable electronic circuits that compute digital logic functions. The functional flexibility of such circuits is important in many applications, including applications of evolutionary principles to circuit design. The functions they compute are at the heart of all digital computation. We explore a vast space of 1045 logic circuits (‘genotypes’) and 1019 logic functions (‘phenotypes’). We demonstrate that circuits that compute the same logic function are connected in large neutral networks that span circuit space. Their robustness or fault-tolerance varies very widely. The vicinity of each neutral network contains circuits with a broad range of novel functions. Two circuits computing different functions can usually be converted into one another via few changes in their architecture. These observations show that properties important for the evolvability of biological systems exist in a commercially important class of electronic circuitry. They also point to generic ways to generate fault-tolerant, adaptable and evolvable electronic circuitry. PMID:20534598

  2. The 'E' factor -- evolving endodontics.

    Science.gov (United States)

    Hunter, M J

    2013-03-01

    Endodontics is a constantly developing field, with new instruments, preparation techniques and sealants competing with trusted and traditional approaches to tooth restoration. Thus general dental practitioners must question and understand the significance of these developments before adopting new practices. In view of this, the aim of this article, and the associated presentation at the 2013 British Dental Conference & Exhibition, is to provide an overview of endodontic methods and constantly evolving best practice. The presentation will review current preparation techniques, comparing rotary versus reciprocation, and question current trends in restoration of the endodontically treated tooth.

  3. Timescales of Quartz Crystallization and the Longevity of the Bishop Giant Magma Body

    Science.gov (United States)

    Gualda, Guilherme A. R.; Pamukcu, Ayla S.; Ghiorso, Mark S.; Anderson, Alfred T.; Sutton, Stephen R.; Rivers, Mark L.

    2012-01-01

    Supereruptions violently transfer huge amounts (100 s–1000 s km3) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted ∼760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain the timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies. PMID:22666359

  4. Timescales of Quartz Crystallization and the Longevity of the Bishop Giant Magma Body

    Energy Technology Data Exchange (ETDEWEB)

    Gualda, Guilherme A.R.; Pamukcu, Ayla S.; Ghiorso, Mark S.; Anderson, Jr. , Alfred T.; Sutton, Stephen R.; Rivers, Mark L. (OFM Res.); (Vanderbilt); (UC)

    2013-04-08

    Supereruptions violently transfer huge amounts (100 s-1000 s km{sup 3}) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted {approx}760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain the timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of <10,000 years, more typically within 500-3,000 years before eruption. We conclude that large-volume, crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies.

  5. Timescales of quartz crystallization and the longevity of the Bishop giant magma body.

    Science.gov (United States)

    Gualda, Guilherme A R; Pamukcu, Ayla S; Ghiorso, Mark S; Anderson, Alfred T; Sutton, Stephen R; Rivers, Mark L

    2012-01-01

    Supereruptions violently transfer huge amounts (100 s-1000 s km(3)) of magma to the surface in a matter of days and testify to the existence of giant pools of magma at depth. The longevity of these giant magma bodies is of significant scientific and societal interest. Radiometric data on whole rocks, glasses, feldspar and zircon crystals have been used to suggest that the Bishop Tuff giant magma body, which erupted ~760,000 years ago and created the Long Valley caldera (California), was long-lived (>100,000 years) and evolved rather slowly. In this work, we present four lines of evidence to constrain the timescales of crystallization of the Bishop magma body: (1) quartz residence times based on diffusional relaxation of Ti profiles, (2) quartz residence times based on the kinetics of faceting of melt inclusions, (3) quartz and feldspar crystallization times derived using quartz+feldspar crystal size distributions, and (4) timescales of cooling and crystallization based on thermodynamic and heat flow modeling. All of our estimates suggest quartz crystallization on timescales of <10,000 years, more typically within 500-3,000 years before eruption. We conclude that large-volume, crystal-poor magma bodies are ephemeral features that, once established, evolve on millennial timescales. We also suggest that zircon crystals, rather than recording the timescales of crystallization of a large pool of crystal-poor magma, record the extended periods of time necessary for maturation of the crust and establishment of these giant magma bodies.

  6. Giant condyloma acuminatum of vulva

    Directory of Open Access Journals (Sweden)

    S. M. Ramiz Ahmed

    2017-09-01

    Full Text Available In this paper, A 23 year old married woman who was diagnosed as a case of giant condyloma acuminatum of vulva measuring about 15 x 8 x 3 cm, irregular surface with multiple projections, oval in shape, firm to hard in consistency, mildly tender, exophytic, cauliflower like growth involving the whole vulva (lower part of mons pubis, labia, vestibule, clitoris, around vaginal opening. Another multiple small lesions were present at perineal region but there was no inguinal lymphadenopathy. She underwent a combined electro cauterization and cryotherapy for small to moderate size multiple primary and recurrent warty lesions and wide surgical excision with fasciocutaneous advancement flaps procedure for a giant lesions in the vulva. Excisional biopsies were performed to detect potential malignancy but malignancy was not found histologically. The patient was advised to first follow-up 1 month after operation when multiple small warty lesions were developed and treated and the subsequent follow-ups for 3 months.

  7. Idiopathic giant right atrial aneurysm

    Science.gov (United States)

    Uppu, Santosh C; Sachdeva, Ritu; Imamura, Michiaki

    2013-01-01

    A 2-year-old boy with an incidental finding of massive cardiomegaly on a chest X-ray was diagnosed with a giant right atrial aneurysm upon further investigation with echocardiography. The patient underwent successful surgical reduction of the right atrium and closure of the patent foramen ovale to prevent thromboembolic complications and to lower the risk of atrial arrhythmias. The resected atrium had paper-thin walls and pathological features of interstitial fibrosis with endocardial thickening. PMID:23626440

  8. Formation of Extrasolar Giant Planets by Core Nucleated Accretion

    Science.gov (United States)

    Bodenheimer, Peter

    into account the energy deposited by accreted solids. The opacity of dust grains is computed in a new and self- consistent fashion that accounts for variations of the size distribution of grains due to coagulation and settling in the envelope. All these effects combined will provide more accurate estimates of the time scales for the accumulation of an envelope and the onset of runaway gas accretion. (3) A 3-D high-resolution, hydrodynamics code will provide gas accretion rates during runaway gas growth, when a giant planet rapidly grows in mass, acquiring most of its gas content. During this phase, tidal interactions with the protoplanetary disk are no longer negligible and, in fact, they will limit the gas accretion rate onto the planet. (4) 3-D calculations will also provide density distributions of torques that will be used to model planetary migration under a range of protoplanetary disk conditions. (5) A non-gray atmosphere code coupled with a planetary evolution code will be used to model the isolation phase of a giant planet, when the planet evolves at a constant mass by cooling and contracting. These calculations will allow us to predict observables of young giant planets that will aid in the interpretation of directly imaged planetary-mass objects and permit more conservative uncertainties to be assigned to the masses of young planetary candidates. Significance to NASA interests: The research will contribute to NASA's goals of understanding how planetary systems form and evolve.

  9. KEPLER RAPIDLY ROTATING GIANT STARS

    Energy Technology Data Exchange (ETDEWEB)

    Costa, A. D.; Martins, B. L. Canto; Bravo, J. P.; Paz-Chinchón, F.; Chagas, M. L. das; Leão, I. C.; Oliveira, G. Pereira de; Silva, R. Rodrigues da; Roque, S.; Oliveira, L. L. A. de; Silva, D. Freire da; De Medeiros, J. R., E-mail: renan@dfte.ufrn.br [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Campus Universitário, Natal RN (Brazil)

    2015-07-10

    Rapidly rotating giant stars are relatively rare and may represent important stages of stellar evolution, resulting from stellar coalescence of close binary systems or accretion of substellar companions by their hosting stars. In the present Letter, we report 17 giant stars observed in the scope of the Kepler space mission exhibiting rapid rotation behavior. For the first time, the abnormal rotational behavior for this puzzling family of stars is revealed by direct measurements of rotation, namely from photometric rotation period, exhibiting a very short rotation period with values ranging from 13 to 55 days. This finding points to remarkable surface rotation rates, up to 18 times the rotation of the Sun. These giants are combined with six others recently listed in the literature for mid-infrared (IR) diagnostics based on Wide-field Infrared Survey Explorer information, from which a trend for an IR excess is revealed for at least one-half of the stars, but at a level far lower than the dust excess emission shown by planet-bearing main-sequence stars.

  10. Determination of the spectroscopic stellar parameters for 257 field giant stars

    OpenAIRE

    Alves, S.; Benamati, L.; Santos, N. C.; Adibekyan, V. Zh.; Sousa, S. G.; Israelian, G.; De Medeiros, J. R.; Lovis, C.; Udry, S.

    2015-01-01

    The study of stellar parameters of planet-hosting stars, such as metallicity and chemical abundances, help us to understand the theory of planet formation and stellar evolution. Here, we present a catalogue of accurate stellar atmospheric parameters and iron abundances for a sample of 257 K and G field evolved stars that are being surveyed for planets using precise radial--velocity measurements as part of the CORALIE programme to search for planets around giants. The analysis was done using a...

  11. The Stability of the Giant Clam Holobiont over Time and during Bleaching Stress

    KAUST Repository

    Pappas, Melissa

    2017-12-01

    The stability of marine photosymbiotic holobionts has major implications for the future of coral reef communities. This study aims to describe the stability of the Red Sea giant clam holobiont over the duration of one year and during induced bleaching stress under laboratory thermal manipulations. Tridacnid clams of the species Tridacna maxima were sampled at three reef locations near the central Saudi coast of the Red Sea. Associated Symbiodinium of Red Sea giant clams have previously been described to be part of only Clade A, which suggests a strong specificity in the clam-algal partnership, but specific types and potential shifting of types within this clade have not been examined for giant clams. The results from this study confirm that tridacnid symbiont types shift over time and the change between three A1 types suggests a biological and functional significance of two undescribed A1 Symbiodinium types. Experimental bleaching shows that Red Sea giant clams, although exposed to rather hot temperatures naturally, will bleach at 34°C after two weeks, and severely bleached clams likely will not recover. During bleaching, Symbiodinium types shift as well, and shift more drastically than seasonal shifts during the year. This shifting may be an evolved characteristic of the giant clam to aid in surviving major changes in the environment. However, more research is needed to determine if these holobionts are capable of keeping up with the global forecast of warming in reef environments.

  12. The bamboo-eating giant panda harbors a carnivore-like gut microbiota, with excessive seasonal variations.

    Science.gov (United States)

    Xue, Zhengsheng; Zhang, Wenping; Wang, Linghua; Hou, Rong; Zhang, Menghui; Fei, Lisong; Zhang, Xiaojun; Huang, He; Bridgewater, Laura C; Jiang, Yi; Jiang, Chenglin; Zhao, Liping; Pang, Xiaoyan; Zhang, Zhihe

    2015-05-19

    The giant panda evolved from omnivorous bears. It lives on a bamboo-dominated diet at present, but it still retains a typical carnivorous digestive system and is genetically deficient in cellulose-digesting enzymes. To find out whether this endangered mammalian species, like other herbivores, has successfully developed a gut microbiota adapted to its fiber-rich diet, we conducted a 16S rRNA gene-based large-scale structural profiling of the giant panda fecal microbiota. Forty-five captive individuals were sampled in spring, summer, and late autumn within 1 year. Significant intraindividual variations in the diversity and structure of gut microbiota across seasons were observed in this population, which were even greater than the variations between individuals. Compared with published data sets involving 124 gut microbiota profiles from 54 mammalian species, these giant pandas, together with 9 captive and 7 wild individuals investigated previously, showed extremely low gut microbiota diversity and an overall structure that diverged from those of nonpanda herbivores but converged with those of carnivorous and omnivorous bears. The giant panda did not harbor putative cellulose-degrading phylotypes such as Ruminococcaceae and Bacteroides bacteria that are typically enriched in other herbivores, but instead, its microbiota was dominated by Escherichia/Shigella and Streptococcus bacteria. Members of the class Clostridia were common and abundant in the giant panda gut microbiota, but most of the members present were absent in other herbivores and were not phylogenetically related with known cellulolytic lineages. Therefore, the giant panda appears not to have evolved a gut microbiota compatible with its newly adopted diet, which may adversely influence the coevolutionary fitness of this herbivore. The giant panda, an endangered mammalian species endemic to western China, is well known for its unique bamboo diet. Unlike other herbivores that have successfully evolved

  13. Giant Cell Arteritis - Who to Refer to?

    Science.gov (United States)

    Lim, L T; Ah-Kee, E Y; Strang, A; Ferguson, A

    2015-06-29

    Giant cell arteritis is a systemic immune-mediated vasculitis affecting the medium and large arteries. Typical symptoms include new headache, jaw claudication, tender temporal artery, polymyalgia rheumatica, fever and anorexia. Visual loss resulting from giant cell arteritis is an ophthalmic emergency and requires immediate assessment and referral to the ophthalmologist for prompt treatment with steroids. This article provides a systematic approach to the diagnosis and management of giant cell arteritis.

  14. Solitary ulcerated congenital giant juvenile xanthogranuloma

    Directory of Open Access Journals (Sweden)

    Su Yuen Ng

    2015-01-01

    Full Text Available A 3-month-old female patient with a giant ulcerated nodule over the back since birth was diagnosed as congenital giant juvenile xanthogranuloma (JXG based on clinical and histopathological examination. Congenital giant JXG with ulceration at birth is a rare presentation of JXG and commonly misdiagnosed. This case emphasizes the importance of being aware of the myriad presentations of JXG in order to make a correct diagnosis and avoid unnecessary investigations or treatment.

  15. Primordial evolvability: Impasses and challenges.

    Science.gov (United States)

    Vasas, Vera; Fernando, Chrisantha; Szilágyi, András; Zachár, István; Santos, Mauro; Szathmáry, Eörs

    2015-09-21

    While it is generally agreed that some kind of replicating non-living compounds were the precursors of life, there is much debate over their possible chemical nature. Metabolism-first approaches propose that mutually catalytic sets of simple organic molecules could be capable of self-replication and rudimentary chemical evolution. In particular, the graded autocatalysis replication domain (GARD) model, depicting assemblies of amphiphilic molecules, has received considerable interest. The system propagates compositional information across generations and is suggested to be a target of natural selection. However, evolutionary simulations indicate that the system lacks selectability (i.e. selection has negligible effect on the equilibrium concentrations). We elaborate on the lessons learnt from the example of the GARD model and, more widely, on the issue of evolvability, and discuss the implications for similar metabolism-first scenarios. We found that simple incorporation-type chemistry based on non-covalent bonds, as assumed in GARD, is unlikely to result in alternative autocatalytic cycles when catalytic interactions are randomly distributed. An even more serious problem stems from the lognormal distribution of catalytic factors, causing inherent kinetic instability of such loops, due to the dominance of efficiently catalyzed components that fail to return catalytic aid. Accordingly, the dynamics of the GARD model is dominated by strongly catalytic, but not auto-catalytic, molecules. Without effective autocatalysis, stable hereditary propagation is not possible. Many repetitions and different scaling of the model come to no rescue. Despite all attempts to show the contrary, the GARD model is not evolvable, in contrast to reflexively autocatalytic networks, complemented by rare uncatalyzed reactions and compartmentation. The latter networks, resting on the creation and breakage of chemical bonds, can generate novel ('mutant') autocatalytic loops from a given set of

  16. Peripartum hysterectomy: an evolving picture.

    LENUS (Irish Health Repository)

    Turner, Michael J

    2012-02-01

    Peripartum hysterectomy (PH) is one of the obstetric catastrophes. Evidence is emerging that the role of PH in modern obstetrics is evolving. Improving management of postpartum hemorrhage and newer surgical techniques should decrease PH for uterine atony. Rising levels of repeat elective cesarean deliveries should decrease PH following uterine scar rupture in labor. Increasing cesarean rates, however, have led to an increase in the number of PHs for morbidly adherent placenta. In the case of uterine atony or rupture where PH is required, a subtotal PH is often sufficient. In the case of pathological placental localization involving the cervix, however, a total hysterectomy is required. Furthermore, the involvement of other pelvic structures may prospectively make the diagnosis difficult and the surgery challenging. If resources permit, PH for pathological placental localization merits a multidisciplinary approach. Despite advances in clinical practice, it is likely that peripartum hysterectomy will be more challenging for obstetricians in the future.

  17. Extreme evolved solar systems (EESS)

    Science.gov (United States)

    Gaensicke, Boris

    2017-08-01

    In just 20 years, we went from not knowing if the solar system is a fluke of Nature to realising that it is totally normal for stars to have planets. More remarkably, it is now clear that planet formation is a robust process, as rich multi-planet systems are found around stars more massive and less massive than the Sun. More recently, planetary systems have been identified in increasingly complex architectures, including circumbinary planets, wide binaries with planets orbiting one or both stellar components, and planets in triple stellar systems.We have also learned that many planetary systems will survive the evolution of their host stars into the white dwarf phase. Small bodies are scattered by unseen planets into the gravitational field of the white dwarfs, tidally disrupt, form dust discs, and eventually accrete onto the white dwarf, where they can be spectroscopically detected. HST/COS has played a critical role in the study these evolved planetary systems, demonstrating that overall the bulk composition of the debris is rocky and resembles in composition the inner the solar system, including evidence for water-rich planetesimals. Past observations of planetary systems at white dwarfs have focused on single stars with main-sequence progenitors of 1.5 to 2.5Msun. Here we propose to take the study of evolved planetary systems into the extremes of parameter ranges to answer questions such as: * How efficient is planet formation around 4-10Msun stars? * What are the metallicities of the progenitors of debris-accreting white dwarfs?* What is the fate of circumbinary planets?* Can star-planet interactions generate magnetic fields in the white dwarf host?

  18. Multiple Giant Coronary Artery Aneurysms

    Science.gov (United States)

    Usuku, Hiroki; Kojima, Sunao; Kuyama, Naoto; Hanatani, Shinsuke; Araki, Satoshi; Tsujita, Kenichi; Tsunoda, Ryusuke; Fukui, Toshihiro; Hokimoto, Seiji

    2017-01-01

    A 74-year-old man was admitted to our hospital with chest pain and dyspnea associated with ST elevation in leads II, III and aVF. An echocardiogram showed an enlarged mass lesion measuring nearly 80 mm. Coronary angiography showed two giant coronary artery aneurysms (CAAs) in the right coronary artery (RCA). CAAs were also seen in the left main trunk and left anterior descending artery. Computed tomography showed the CAA in the RCA was ruptured into the right atrium. We therefore diagnosed this patient with multiple CAAs, myocardial infarction and coronary artery rupture. He underwent successful surgical excision and coronary bypass surgery. PMID:28768966

  19. Rare Giant Prevertebral Thoracic Myelomeningocele.

    Science.gov (United States)

    Choi, Bryan D; Fehnel, Katie P; Butler, William E

    2018-01-01

    Here we report a 72-year-old man who presented with complaint of sudden-onset weakness and impaired sensation in the left lower extremity. Radiographic evaluation revealed a congenital malformation with multiple formation defects including a giant thoracic prevertebral myelomeningocele. Following microsurgical detethering of the spinal cord, the patient recovered ambulation with assist. While thoracic myelomeningoceles are themselves rare, in this case the patient presented at a late age and responded well to conservative management. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Giant Rhinolith: A Case Report

    Directory of Open Access Journals (Sweden)

    Ji-Chang Hsiao

    2005-12-01

    Full Text Available A rhinolith is a stone that forms in the nose. It occurs as a result of the solidification of mucus and nasal debris by mineral salts, calcium, magnesium phosphate and carbonate. It can be seen on radiographs as a radiopaque object in the nasal fossa and may be confused with several pathologic entities that will call for more invasive surgical procedures. We present the first case of a giant rhinolith, possibly arising from aspergillosis, and discuss its clinical and radiologic features.

  1. Giant magneto-resistance devices

    CERN Document Server

    Hirota, Eiichi; Inomata, Koichiro

    2002-01-01

    This book deals with the application of giant magneto-resistance (GMR) effects to electronic devices. It will appeal to engineers and graduate students in the fields of electronic devices and materials. The main subjects are magnetic sensors with high resolution and magnetic read heads with high sensitivity, required for hard-disk drives with recording densities of several gigabytes. Another important subject is novel magnetic random-access memories (MRAM) with non-volatile non-destructive and radiation-resistant characteristics. Other topics include future GMR devices based on bipolar spin transistors, spin field-effect transistors (FETs) and double-tunnel junctions.

  2. Giant viruses, giant chimeras: The multiple evolutionary histories of Mimivirus genes

    Directory of Open Access Journals (Sweden)

    Brochier-Armanet Céline

    2008-01-01

    Full Text Available Abstract Background Although capable to evolve, viruses are generally considered non-living entities because they are acellular and devoid of metabolism. However, the recent publication of the genome sequence of the Mimivirus, a giant virus that parasitises amoebas, strengthened the idea that viruses should be included in the tree of life. In fact, the first phylogenetic analyses of a few Mimivirus genes that are also present in cellular lineages suggested that it could define an independent branch in the tree of life in addition to the three domains, Bacteria, Archaea and Eucarya. Results We tested this hypothesis by carrying out detailed phylogenetic analyses for all the conserved Mimivirus genes that have homologues in cellular organisms. We found no evidence supporting Mimivirus as a new branch in the tree of life. On the contrary, our phylogenetic trees strongly suggest that Mimivirus acquired most of these genes by horizontal gene transfer (HGT either from its amoebal hosts or from bacteria that parasitise the same hosts. The detection of HGT events involving different eukaryotic donors suggests that the spectrum of hosts of Mimivirus may be larger than currently known. Conclusion The large number of genes acquired by Mimivirus from eukaryotic and bacterial sources suggests that HGT has been an important process in the evolution of its genome and the adaptation to parasitism.

  3. CERN internal communication is evolving

    CERN Multimedia

    2016-01-01

    CERN news will now be regularly updated on the CERN People page (see here).      Dear readers, All over the world, communication is becoming increasingly instantaneous, with news published in real time on websites and social networks. In order to keep pace with these changes, CERN's internal communication is evolving too. From now on, you will be informed of what’s happening at CERN more often via the “CERN people” page, which will frequently be updated with news. The Bulletin is following this trend too: twice a month, we will compile the most important articles published on the CERN site, with a brand-new layout. You will receive an e-mail every two weeks as soon as this new form of the Bulletin is available. If you have interesting news or stories to share, tell us about them through the form at: https://communications.web.cern.ch/got-story-cern-website​. You can also find out about news from CERN in real time...

  4. Totally thrombosed giant anterior communicating artery aneurysm

    Directory of Open Access Journals (Sweden)

    V R Roopesh Kumar

    2015-01-01

    Full Text Available Giant anterior communicating artery aneurysmsarerare. Apatient presented with visual dysfunction, gait ataxia and urinary incontinence. MRI showed a giant suprasellar mass.At surgery, the lesion was identified as being an aneurysm arising from the anterior communicating artery.The difficulty in preoperative diagnosis and relevant literature are reviewed.

  5. Surgical treatment for giant incisional hernia

    DEFF Research Database (Denmark)

    Eriksson, A; Rosenberg, J; Bisgaard, T

    2014-01-01

    INTRODUCTION: Repair for giant incisional hernias is a challenge due to unacceptable high morbidity and recurrence rates. Several surgical techniques are available, but all are poorly documented. This systematic review was undertaken to evaluate the existing literature on repair for giant...... procedure and severely lack evidence-based research from high-quality, large-scaled randomised studies....

  6. Giant pubertal prolactinoma: Complete resolution following short ...

    African Journals Online (AJOL)

    ... in micro‑ and macro‑adenomas unless an urgent treatment is necessary. First line treatment is always medical with dopamine agonists. In this report, we presented a patient with pubertal arrest and giant prolactinoma that disappeared in a short time with cabergoline treatment. Keywords: Cabergoline, giant prolactinoma, ...

  7. growing African giant rats Cricetomys gambianus

    African Journals Online (AJOL)

    Thermoregulation and evaporative water loss in growing African giant rats Cricetomys gambianus. M.H. Knight. Mammal Research Institute, University of Pretoria, Pretoria. With an increase in mass, weaned giant rat pups. Cricetomys gambianus, showed a corresponding decline in mass specific metabolism, conductance ...

  8. Scenarios of giant planet formation and evolution and their impact on the formation of habitable terrestrial planets.

    Science.gov (United States)

    Morbidelli, Alessandro

    2014-04-28

    In our Solar System, there is a clear divide between the terrestrial and giant planets. These two categories of planets formed and evolved separately, almost in isolation from each other. This was possible because Jupiter avoided migrating into the inner Solar System, most probably due to the presence of Saturn, and never acquired a large-eccentricity orbit, even during the phase of orbital instability that the giant planets most likely experienced. Thus, the Earth formed on a time scale of several tens of millions of years, by collision of Moon- to Mars-mass planetary embryos, in a gas-free and volatile-depleted environment. We do not expect, however, that this clear cleavage between the giant and terrestrial planets is generic. In many extrasolar planetary systems discovered to date, the giant planets migrated into the vicinity of the parent star and/or acquired eccentric orbits. In this way, the evolution and destiny of the giant and terrestrial planets become intimately linked. This paper discusses several evolutionary patterns for the giant planets, with an emphasis on the consequences for the formation and survival of habitable terrestrial planets. The conclusion is that we should not expect Earth-like planets to be typical in terms of physical and orbital properties and accretion history. Most habitable worlds are probably different, exotic worlds.

  9. RADIO EMISSION FROM RED-GIANT HOT JUPITERS

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, Yuka [Earth-Life Science Institute, Tokyo Institute of Technology, Tokyo, 152-8550 (Japan); Spiegel, David S. [Analytics and Algorithms, Stitch Fix, San Francisco, CA 94103 (United States); Mroczkowski, Tony [Naval Research Laboratory, 4555 Overlook Ave SW, Washington, DC 20375 (United States); Nordhaus, Jason [Department of Science and Mathematics, National Technical Institute for the Deaf, Rochester Institute of Technology, Rochester, NY 14623 (United States); Zimmerman, Neil T. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Parsons, Aaron R. [Astronomy Department, University of California, Berkeley, CA (United States); Mirbabayi, Mehrdad [Astrophysics Department, Institute for Advanced Study, Princeton, NJ 08540 (United States); Madhusudhan, Nikku, E-mail: yuka.fujii@elsi.jp [Astronomy Department, University of Cambridge (United Kingdom)

    2016-04-01

    When planet-hosting stars evolve off the main sequence and go through the red-giant branch, the stars become orders of magnitudes more luminous and, at the same time, lose mass at much higher rates than their main-sequence counterparts. Accordingly, if planetary companions exist around these stars at orbital distances of a few au, they will be heated up to the level of canonical hot Jupiters and also be subjected to a dense stellar wind. Given that magnetized planets interacting with stellar winds emit radio waves, such “Red-Giant Hot Jupiters” (RGHJs) may also be candidate radio emitters. We estimate the spectral auroral radio intensity of RGHJs based on the empirical relation with the stellar wind as well as a proposed scaling for planetary magnetic fields. RGHJs might be intrinsically as bright as or brighter than canonical hot Jupiters and about 100 times brighter than equivalent objects around main-sequence stars. We examine the capabilities of low-frequency radio observatories to detect this emission and find that the signal from an RGHJ may be detectable at distances up to a few hundred parsecs with the Square Kilometer Array.

  10. Giant subtidal stromatolites forming in normal salinity waters

    Science.gov (United States)

    Dill, R.F.; Shinn, E.A.; Jones, A.T.; Kelly, K.; Steinen, R.P.

    1986-01-01

    We report here the discovery of giant lithified subtidal columnar stromatolites (>2 m high) growing in 7-8 m of clear oceanic water in current-swept channels between the Exuma Islands on the eastern Bahama Bank. They grow by trapping ooid and pelletal carbonate sand and synsedimentary precipitation of carbonate cement within a field of giant megaripples. The discovery is important to geologists and biologists because similar organo-sedimentary structures built by a combination of cementation and the trapping of sediment by microbes were the dominant fossil types during the Precambrian. Stromatolites are thought to have been responsible for the production of free oxygen and thus the evolution of animal life1,2. Until the discovery of small lithified subtidal columnar stromatolites in the Bahamas3, the only subtidal marine examples known to be living while undergoing lithification were in the hypersaline waters of Hamelin Pool at Shark Bay, Western Australia4-7. Shark Bay stromatolites range from intertidal to the shallow subtidal with the larger columns reaching 1 m in height. The Shark Bay stromatolites have strongly influenced geological interpretation; by analogy, many ancient stromatolites have been considered to have grown in intertidal and/or hypersaline conditions8, although hypersalinity was not a necessity for growth during the Precambrian because grazing metazoan life had not then evolved. ?? 1986 Nature Publishing Group.

  11. Radio Emission from Red-Giant Hot Jupiters

    Science.gov (United States)

    Fujii, Yuka; Spiegel, David S.; Mroczkowski, Tony; Nordhaus, Jason; Zimmerman, Neil T.; Parsons, Aaron R.; Mirbabayi, Mehrdad; Madhusudhan, Nikku

    2016-01-01

    When planet-hosting stars evolve off the main sequence and go through the red-giant branch, the stars become orders of magnitudes more luminous and, at the same time, lose mass at much higher rates than their main sequence counterparts. Accordingly, if planetary companions exist around these stars at orbital distances of a few au, they will be heated up to the level of canonical hot Jupiters and also be subjected to a dense stellar wind. Given that magnetized planets interacting with stellar winds emit radio waves, such "Red-Giant Hot Jupiters" (RGHJs) may also be candidate radio emitters. We estimate the spectral auroral radio intensity of RGHJs based on the empirical relation with the stellar wind as well as a proposed scaling for planetary magnetic fields. RGHJs might be intrinsically as bright as or brighter than canonical hot Jupiters and about 100 times brighter than equivalent objects around main-sequence stars. We examine the capabilities of low-frequency radio observatories to detect this emission and find that the signal from an RGHJ may be detectable at distances up to a few hundred parsecs with the Square Kilometer Array.

  12. [Giant ameloblastoma of the mandible].

    Science.gov (United States)

    Catherine, Z; Isaac, S; Cotton, F; Roch, J; Rousset, M; Bouletreau, P; Breton, P

    2013-04-01

    Giant ameloblastomas are more common in developing countries. They raise a serious problem of management. We present the case of one of the largest ameloblastoma ever reported. A 48-year-old Congolese female patient was referred for mandibular swelling having begun 23 years before and now inducing severe functional disorders. A cephalic CT scan revealed a multicystic mass, 30×18×10cm in size, with a typical "soap bubble" presentation, and with thinned and inflated cortical bone. The treatment was sub-total segmental mandibulectomy with immediate reconstruction using a fibular free flap, modeled on the sampling site by four ostectomies. The pathological examination confirmed the diagnosis of a benign follicular and plexiform ameloblastoma. The excess of soft tissue was treated with a right commissuroplasty on the 15th postoperative day. There was no complication. Radical treatment followed by immediate reconstruction using a free flap is the treatment of choice for giant mandibular ameloblastomas, when considering immediate functional and esthetic benefits. This is a prime concern for patients with a difficult access to health care and for whom long-term follow-up is not feasible. Copyright © 2013. Published by Elsevier Masson SAS.

  13. [Giant aneurysm of fast development].

    Science.gov (United States)

    Castilla, J M; Martín-Velasco, V; Rodríguez-Salazar, A

    2002-06-01

    The percentage of aneurysms measuring more than 2'5 cm in diameter ranges from 3 to 13%, and occur more commonly in females. They come to clinical attention later than nongiant aneurysms, but 20% of them appear in patients 20 years of age or younger. Its natural history is incompletely understood. We present the case of a 24-year-old female admitted following a generalized seizure with postictal dysphasia and right hemiparesis caused by a subarachnoid hemorrhage due to a ruptured giant aneurysm located in the left temporal fossa, who died few hours later because of rebleeding. This patient had been followed during the last seven years at our unit because of untreated frontal osteomas, without evidence of any intracranial lesion in the computerized axial tomography (CT). Some months before her death, she had suffered a left micotic otitis, and she was studied because of the reappearance of her left cephalalgia without neurological deficit. This case is another evidence of quick appearance of a giant aneurysm, "silent" until the fatal outcome.

  14. On the observational characteristics of lithium-enhanced giant stars in comparison with normal red giants†

    Science.gov (United States)

    Takeda, Yoichi; Tajitsu, Akito

    2017-08-01

    While lithium is generally deficient in the atmosphere of evolved giant stars because of the efficient mixing-induced dilution, a small fraction of red giants show unusually strong Li lines indicative of conspicuous abundance excess. With the aim of shedding light on the origin of these peculiar stars, we carried out a spectroscopic study on the observational characteristics of 20 selected bright giants already known to be Li-rich from past studies, in comparison with the reference sample of a large number of normal late G-early K giants. Special attention was paid to clarifying any difference between the two samples from a comprehensive point of view (i.e., with respect to stellar parameters, rotation, activity, kinematic properties, 6Li/7Li ratio, and the abundances of Li, Be, C, O, Na, S, and Zn). Our sample stars are roughly divided into a “bump/clump group” and a “luminous group” according to their positions on the HR diagram. Regarding the former group [1.5 ≲ log (L/L⊙) ≲ 2 and M ∼ 1.5-3 M⊙], Li-enriched giants and normal giants appear practically similar in almost all respects except for Li, suggesting that surface Li enhancement in this group may be a transient episode which normal giants undergo at certain evolutionary stages in their lifetime. Meanwhile, those Li-rich giants belonging to the latter group [log (L/L⊙) ∼ 3 and M ∼ 3-5 M⊙] appear more anomalous in the sense that they tend to show higher rotation as well as higher activity, and that their elemental abundances (especially those derived from high-excitation lines) are apt to show apparent overabundances, though this might be due to a spurious effect reflecting the difficulty of abundance derivation in stars of higher rotation and activity. Our analysis confirmed considerable Be deficiency as well as absence of 6Li as the general characteristics of Li-rich giants under study, which implies that engulfment of planets is rather unlikely for the origin of Li-enrichment.

  15. The evolution of giant flightless birds and novel phylogenetic relationships for extinct fowl (Aves, Galloanseres)

    Science.gov (United States)

    Worthy, Trevor H.; Degrange, Federico J.; Handley, Warren D.; Lee, Michael S. Y.

    2017-10-01

    The extinct dromornithids, gastornithids and phorusrhacids are among the most spectacular birds to have ever lived, with some giants exceeding 500 kg. The affinities and evolution of these and other related extinct birds remain contentious, with previous phylogenetic analyses being affected by widespread convergence and limited taxon sampling. We address these problems using both parsimony and tip-dated Bayesian approaches on an expansive taxon set that includes all key extinct flightless and flighted (e.g. Vegavis and lithornithids) forms, an extensive array of extant fowl (Galloanseres), representative Neoaves and palaeognaths. The Paleogene volant Lithornithidae are recovered as stem palaeognaths in the Bayesian analyses. The Galloanseres comprise four clades inferred to have diverged in the Late Cretaceous on Gondwana. In addition to Anseriformes and Galliformes, we recognize a robust new clade (Gastornithiformes) for the giant flightless Dromornithidae (Australia) and Gastornithidae (Eurasia, North America). This clade exhibits parallels to ratite palaeognaths in that flight presumably was lost and giant size attained multiple times. A fourth clade is represented by the Cretaceous Vegavis (Antarctica), which was strongly excluded from Anseriformes; thus, a crucial molecular calibration point needs to be reconsidered. The presbyornithids Wilaru (Australia) and Presbyornis (Northern Hemisphere) are robustly found to be the sister group to Anatoidea (Anseranatidae + Anatidae), a relatively more basal position than hitherto recognized. South America's largest bird, Brontornis, is not a galloansere, but a member of Neoaves related to Cariamiformes; therefore, giant Galloanseres remain unknown from this continent. Trait analyses showed that while gigantism and flightlessness evolved repeatedly in groups, diet is constrained by phylogeny: all giant Galloanseres and palaeognaths are herbivores or mainly herbivorous, and giant neoavians are zoophagous or omnivorous.

  16. SYNOVIAL GIANT CELL TUMOR OF THE KNEE.

    Science.gov (United States)

    Abdalla, Rene Jorge; Cohen, Moisés; Nóbrega, Jezimar; Forgas, Andrea

    2009-01-01

    Synovial giant cell tumor is a benign neoplasm, rarely reported in the form of malignant metastasis. Synovial giant cell tumor most frequently occurs on the hand, and, most uncommon, on the ankle and knee. In the present study, the authors describe a rare case of synovial giant cell tumor on the knee as well as the treatment approach. Arthroscopy has been shown, in this case, to be the optimal method for treating this kind of lesion, once it allowed a less aggressive approach, while providing good visualization of all compartments of knee joint and full tumor resection.

  17. GIANT CONGENITAL NEVUS – CASE REPORT

    Directory of Open Access Journals (Sweden)

    Danijela Popovic

    2006-01-01

    Full Text Available Congenital nevomelanocitic nevi (CN are benign melanocitic proliferations present at birth. The incidence of giant CN is 0,002% in the newborns. The paper presents the case of a 20-year old female with giant CN on the skin of the right hand. Dermoscopy is very useful in differential diagnosis of pigmented skin lesions. Dermoscopic characteristics of CN are the presence of uniform globules - the "pebble stone" pattern. Giant CN overtaking more than 5% of the skin has an increased risk of malignant melanoma. Possible therapy modalities for CN are: excision with grafts, dermabrasion, curettage and laser. Periodical check-ups are necessary.

  18. Giant Congenital Melanocytic Naevi: review of literature

    Directory of Open Access Journals (Sweden)

    A. Marchesi

    2012-04-01

    Full Text Available giant congenital pigmented naevi is a great reconstructive challenge for the pediatric and plastic surgeons. due to the increased risk of malignant transformation in such lesions, many procedures have been used to remove giant congenital naevi like dermoabrasion, laser treatment or surgical excision combined with reconstruction through skin expansion or skin grafting; among these, only a complete excision can offer an efficacious treatment. in our centre we use the “tissue expansion” technique in order to achieve a sufficient quantity of normal skin to perform a both staged and radical excision of these giant lesions.

  19. Direct Imaging of Giant Exoplanets

    Science.gov (United States)

    Tamura, Motohide

    Since the first detection of exoplanets around a Sun-like star 51 Peg in 1995, their detection and characterization are mainly led by indirect methods such as radial velocity and transit methods. However, recent progresses of observational techniques have finally enabled the direct imaging observations of giant planets of solar-system-scale orbit (with their semi-major axes less than about 50 AU) around A-type stars (e.g., Marois et al. 2008, 2010) and G-type stars (e.g., Kuzuhara et al. 2013). Direct imaging is useful to obtain the physical and atmospheric parameters of exoplanets. In fact not only colors but also a medium-resolution spectroscopy of such planets has been successfully obtained for their atmospheric characterization (Barman et al. 2013). Their masses are typically a few to ~10 Jupiter masses and they orbit at a Saturn- to-Pluto distance. Therefore, like hot-Jupiters and super-Earths they are unlike any solar-system planets, and called wide-orbit giant planets. A recent large search for planets and disk on the Subaru 8.2-m telescope (SEEDS project) has detected a 3-5 Jupiter-masses planet around a Sun-like star GJ 504 (Kuzuhara et al. 2013). It is the coolest planetary companion so far directly imaged and its near-infrared color is “bluer” than that of other directly imaged planets. In this contribution, I will review the recent progresses on direct imaging of exoplanets, highlight the results of the SEEDS project, and discuss the future developments.

  20. Analysis of the cytochrome c oxidase subunit II (COX2) gene in giant panda, Ailuropoda melanoleuca.

    Science.gov (United States)

    Ling, S S; Zhu, Y; Lan, D; Li, D S; Pang, H Z; Wang, Y; Li, D Y; Wei, R P; Zhang, H M; Wang, C D; Hu, Y D

    2017-01-23

    The giant panda, Ailuropoda melanoleuca (Ursidae), has a unique bamboo-based diet; however, this low-energy intake has been sufficient to maintain the metabolic processes of this species since the fourth ice age. As mitochondria are the main sites for energy metabolism in animals, the protein-coding genes involved in mitochondrial respiratory chains, particularly cytochrome c oxidase subunit II (COX2), which is the rate-limiting enzyme in electron transfer, could play an important role in giant panda metabolism. Therefore, the present study aimed to isolate, sequence, and analyze the COX2 DNA from individuals kept at the Giant Panda Protection and Research Center, China, and compare these sequences with those of the other Ursidae family members. Multiple sequence alignment showed that the COX2 gene had three point mutations that defined three haplotypes, with 60% of the sequences corresponding to haplotype I. The neutrality tests revealed that the COX2 gene was conserved throughout evolution, and the maximum likelihood phylogenetic analysis, using homologous sequences from other Ursidae species, showed clustering of the COX2 sequences of giant pandas, suggesting that this gene evolved differently in them.

  1. Morphological aspects of giant cells in giant cell arteritis: an electron-microscopic and immunocytochemical study.

    Science.gov (United States)

    Nordborg, E; Bengtsson, B A; Petursdottir, V; Nordborg, C

    1997-01-01

    To compare the morphology of foreign body and Langhans giant cells in the two different inflammatory phases of giant cell arteritis (GCA). Electron microscopy was performed on 6 positive temporal arterial biopsies. Light microscopy and immunocytochemistry for macrophage-associated antigen (KP1) and alpha-smooth muscle actin (alpha-SMA) were performed on 16 positive biopsies. A focal granulomatous reaction with foreign body giant cells was found only in association with the internal elastic membrane (IEM) in atrophic arterial segments, which often displayed calcification of the IEM. Diffuse invasion of lymphocytes and monocytes/macrophages affected non-atrophic as well as atrophic arterial segments. Within such segments Langhans giant cells were found in all layers of the wall. Electron microscopy of biopsies displaying the focal foreign body reaction revealed that large cells devoid of lysosomes but with cytoplasmic densities, tightly packed cytoplasmic filaments and numerous micropinocytotic vesicles formed clusters close to calcified parts of the internal elastic membrane. Furthermore, foreign body giant cells were surrounded by large cells devoid of lysosomes. Lysosomes tended to concentrate in central parts of the foreign body giant cells. In the diffusely inflamed arteries, the Langhans giant cells were surrounded by mononuclear cells rich in lysosomes. The lysosomes in the Langhans giant cells were more evenly distributed than in foreign body giant cells. Immunocytochemistry of biopsies displaying the focal granulomatous reaction revealed an uneven, often central immunoreactivity for the macrophage marker (KP1) in the foreign body giant cells, and immunostaining for alpha-smooth muscle antigen (alpha-SMA) showed their poor delineation from the surrounding vascular smooth muscle cells. The Langhans giant cells in the diffusely inflamed arteries displayed a strong even cytoplasmic immunoreactivity for KP1 and a distinct delineation from the smooth muscle cells

  2. DNA evolved to minimize frameshift mutations

    OpenAIRE

    Agoni, Valentina

    2013-01-01

    Point mutations can surely be dangerous but what is worst than to lose the reading frame?! Does DNA evolved a strategy to try to limit frameshift mutations?! Here we investigate if DNA sequences effectively evolved a system to minimize frameshift mutations analyzing the transcripts of proteins with high molecular weights.

  3. The evolved slowly pulsating B star 18 Peg

    Directory of Open Access Journals (Sweden)

    Irrgang Andreas

    2017-01-01

    Full Text Available The predicted width of the upper main sequence in stellar evolution models depends on the empirical calibration of the convective overshooting parameter. Despite decades of discussions, its precise value is still unknown and further observational constraints are required to gauge it. Irrgang et al. ([1] showed that the B3 III giant 18 Peg is one of the most evolved members of the class of slowly pulsating B (SPB stars and, thus, bears tremendous potential to derive a tight lower limit for the width of the upper main sequence. In addition, 18 Peg turns out to be part of a single-lined spectroscopic binary system with an eccentric, more than 6-year orbit. The orbital solution, in combination with the absence of additional signatures of the secondary component in the spectroscopic data and the spectral energy distribution, lead to the conclusion that all the observations of 18 Peg are fully compatible with the assumption that the secondary component is either a main-sequence star with a mass of 1-4 M⊙ or a neutron star.

  4. Are Langhans giant cells precursors of foreign-body giant cells?

    Science.gov (United States)

    van der Rhee, H J; Hillebrands, W; Daems, W T

    1978-01-01

    Granulomas were induced in rats by subcutaneous implantation of pieces of Melinex plastic into the dorsum. The pieces of Melinex were removed at intervals varying from 16 h to 14 days, and the adherent cells were studied morphologically and quantitatively. Giant cell formation started about 32 h after implantation. The first giant cells to appear were of the Langhans type. Two days after implantation, most of the giant cells are still Langhans-type cells. A few giant cells of the foreign-body type and transition forms between the Langhans and foreign-body types are also present. From the third day on, the foreign-body type gradually becomes predominant. Independent of the duration of implantation, giant cells with 3, 4, or 5 nuclei are virtually without exception of the Langhans type. The higher the number of nuclei between 6 and 30, the more cells are of the foreign-body type. Giant cells with 30 or more nuclei are all foreign-body type. The findings are discussed in the light of current knowledge concerning giant cell formation. It is concluded that under the present experimental conditions, Langhans-type giant cells are the precursors of foreign-body-type giant cells.

  5. Giant Plagioclase Basalts, eruption rate versus time

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 111; Issue 4. Giant Plagioclase Basalts, eruption rate versus time: Response to Sheth's comments and some additional thoughts. Gautam Sen. Volume 111 Issue 4 December 2002 pp 487-488 ...

  6. Genetics Home Reference: giant congenital melanocytic nevus

    Science.gov (United States)

    ... Encyclopedia: Giant Congenital Nevus Nevus Outreach: Treatment Options Primary Care Dermatology Society General Information from MedlinePlus (5 links) Diagnostic Tests Drug Therapy Genetic Counseling Palliative Care Surgery and Rehabilitation Related Information How are ...

  7. Tests of the Giant Impact Hypothesis

    Science.gov (United States)

    Jones, J. H.

    1998-01-01

    The giant impact hypothesis has gained popularity as a means of explaining a volatile-depleted Moon that still has a chemical affinity to the Earth. As Taylor's Axiom decrees, the best models of lunar origin are testable, but this is difficult with the giant impact model. The energy associated with the impact would be sufficient to totally melt and partially vaporize the Earth. And this means that there should he no geological vestige of Barber times. Accordingly, it is important to devise tests that may be used to evaluate the giant impact hypothesis. Three such tests are discussed here. None of these is supportive of the giant impact model, but neither do they disprove it.

  8. Prenatally-detected giant lymphatic malformation.

    Science.gov (United States)

    Sværdborg, Mille; Keller, Johnny; Schrøder, Henrik; Petersen, Olav B; Stausbøl-Grøn, Brian; Engberg Damsgaard, Tine

    2011-12-01

    We present a case of a giant lymphatic malformation of the chest and abdominal wall that was diagnosed in the third trimester of pregnancy. It was treated by one stage excision with good functional and cosmetic outcomes.

  9. AFSC/ABL: Female Giant Grenadier maturity

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Giant grenadiers Albatrossia pectoralis are caught as bycatch in deep-sea commercial fisheries in relatively large numbers. The population appears to be stable,...

  10. Vibrationally excited water emission at 658 GHz from evolved stars

    Science.gov (United States)

    Baudry, A.; Humphreys, E. M. L.; Herpin, F.; Torstensson, K.; Vlemmings, W. H. T.; Richards, A. M. S.; Gray, M. D.; De Breuck, C.; Olberg, M.

    2018-01-01

    Context. Several rotational transitions of ortho- and para-water have been identified toward evolved stars in the ground vibrational state as well as in the first excited state of the bending mode (v2 = 1 in (0, 1, 0) state). In the latter vibrational state of water, the 658 GHz J = 11,0-10,1 rotational transition is often strong and seems to be widespread in late-type stars. Aims: Our main goals are to better characterize the nature of the 658 GHz emission, compare the velocity extent of the 658 GHz emission with SiO maser emission to help locate the water layers and, more generally, investigate the physical conditions prevailing in the excited water layers of evolved stars. Another goal is to identify new 658 GHz emission sources and contribute in showing that this emission is widespread in evolved stars. Methods: We have used the J = 11,0-10,1 rotational transition of water in the (0, 1, 0) vibrational state nearly 2400 K above the ground-state to trace some of the physical conditions of evolved stars. Eleven evolved stars were extracted from our mini-catalog of existing and potential 658 GHz sources for observations with the Atacama Pathfinder EXperiment (APEX) telescope equipped with the SEPIA Band 9 receiver. The 13CO J = 6-5 line at 661 GHz was placed in the same receiver sideband for simultaneous observation with the 658 GHz line of water. We have compared the ratio of these two lines to the same ratio derived from HIFI earlier observations to check for potential time variability in the 658 GHz line. We have compared the 658 GHz line properties with our H2O radiative transfer models in stars and we have compared the velocity ranges of the 658 GHz and SiO J = 2-1, v = 1 maser lines. Results: Eleven stars have been extracted from our catalog of known or potential 658 GHz evolved stars. All of them show 658 GHz emission with a peak flux density in the range ≈50-70 Jy (RU Hya and RT Eri) to ≈2000-3000 Jy (VY CMa and W Hya). Five Asymptotic Giant Branch (AGB

  11. Hepatic Giant Cell Arteritis and Polymyalgia Rheumatica

    OpenAIRE

    Duerksen, Donald R; Jewell, Laurence D.; Bain, Vincent G

    1994-01-01

    Polymyalgia rheumatica (PMR) is a clinical syndrome of the elderly characterized by malaise, proximal muscle aching and stiffness, low grade fever, elevated erythrocyte sedimentation rare and the frequent association with temporal giant cell arteritis. The authors describe a case of PMR associated with hepatic giant cell arteritis. This lesion has been described in two other clinical reports. The distribution of the arteritis may be patchy; in this report, diagnosis was made with a wedge biop...

  12. Large-Spin Expansions of Giant Magnons

    OpenAIRE

    Linardopoulos, Georgios

    2015-01-01

    This is a talk delivered at the Workshop on Quantum Fields and Strings of the 2014 Corfu Summer Institute. We discuss how giant magnons emerge in the context of the AdS5/CFT4 correspondence as the gravity duals of N = 4 super Yang-Mills magnon excitations. Then we present a new analytic expression for the dispersion relation of classical finite-size giant magnons with Lambert's W-function.

  13. Granuloma with langhans giant cells: An overview

    OpenAIRE

    Kumar, S Nalin; Prasad, T Srinivasa; Narayan, P Anantha; Muruganandhan, J

    2013-01-01

    Granuloma formation with multinucleated giant cells is seen in numerous diseases. A granuloma is a focus of chronic inflammation consisting of a microscopic aggregation of macrophages surrounded by a collar of lymphocytes and plasma cells. In this article, we present a case of granuloma formation with multiple Langhans giant cells along with an overview of the differential diagnoses, which include mycobacterium diseases, other bacterial infections, fungal infections, protozoal infections, and...

  14. Granuloma with langhans giant cells: An overview.

    Science.gov (United States)

    Kumar, S Nalin; Prasad, T Srinivasa; Narayan, P Anantha; Muruganandhan, J

    2013-09-01

    Granuloma formation with multinucleated giant cells is seen in numerous diseases. A granuloma is a focus of chronic inflammation consisting of a microscopic aggregation of macrophages surrounded by a collar of lymphocytes and plasma cells. In this article, we present a case of granuloma formation with multiple Langhans giant cells along with an overview of the differential diagnoses, which include mycobacterium diseases, other bacterial infections, fungal infections, protozoal infections, and other granulomatous diseases.

  15. BD+48 740-Li OVERABUNDANT GIANT STAR WITH A PLANET: A CASE OF RECENT ENGULFMENT?

    Energy Technology Data Exchange (ETDEWEB)

    Adamow, M.; Niedzielski, A.; Nowak, G. [Torun Centre for Astronomy, Nicolaus Copernicus University, Gagarina 11, 87-100 Torun (Poland); Villaver, E. [Departamento de Fisica Teorica, Universidad Autonoma de Madrid, Cantoblanco 28049 Madrid (Spain); Wolszczan, A. [Department of Astronomy and Astrophysics, Pennsylvania State University, 525 Davey Laboratory, University Park, PA 16802 (United States)

    2012-07-20

    We report the discovery of a unique object, BD+48 740, a lithium overabundant giant with A(Li) = 2.33 {+-} 0.04 (where A(Li) = log n{sub Li}/n{sub H} + 12), that exhibits radial velocity (RV) variations consistent with a 1.6 M{sub J} companion in a highly eccentric, e = 0.67 {+-} 0.17, and extended, a 1.89 AU (P = 771 days), orbit. The high eccentricity of the planet is uncommon among planetary systems orbiting evolved stars and so is the high lithium abundance in a giant star. The ingestion by the star of a putative second planet in the system originally in a closer orbit could possibly allow for a single explanation to these two exceptional facts. If the planet candidate is confirmed by future RV observations, it might represent the first example of the remnant of a multiple planetary system recently affected by stellar evolution.

  16. Giant cell ependymoma: a case report.

    Science.gov (United States)

    Adamek, Dariusz; Dec, Malgorzata; Sobol, Grazyna; Urbanowicz, Barbara; Jaworski, Marian

    2008-02-01

    Ependymomas account for 3-9% of all neuroepithelial tumors. A peculiar variant of ependymoma known as "giant cell ependymoma" ("GCE") is especially rarely reported, it may pose some difficulties for the diagnosing neuropathologist. Here we present a case of a giant cell ependymoma occuring in a 17-year-old patient with the history of 2-year recurrent headaches and a 1-month history of vision impairment. CT scanning demonstrated a mass in the left occipital lobe, arising from the occipital horn of the lateral ventricle. Histological, immunohistochemical and electron microscopic findings were consistent with high-grade ependymoma. Especially striking was the presence of bizzare pleomorphic giant cells which predominated in the tumor tissue. As a result the diagnosis of GCE was established. This type of neoplasm necessitates, at least in theory, differentiation with anaplastic oligodendroglioma, clear cell ependymoma, pleomorphic xanthoastrocytoma, giant cell glioblastoma, and subependymal giant cell astrocytoma. To date giant cell ependymomas (GCEs) were reported in seven cases in the literature. To the best of our knowledge this is the 8th case in the literature. In spite of apparently "worrisome" histology GCE seems to be a neoplasm with a relatively good prognosis.

  17. Mining the HST Treasury: The ASTRAL Reference Spectra for Evolved M Stars

    Science.gov (United States)

    Carpenter, K. G.; Ayres, T.; Harper, G.; Kober, G.; Wahlgren, G. M.

    2012-01-01

    The "Advanced Spectral Library (ASTRAL) Project: Cool Stars" (PI = T. Ayres) is an HST Cycle 18 Treasury Program designed to collect a definitive set of representative, high-resolution (R greater than 100,000) and high signal/noise (S/N greater than 100) UV spectra of eight F-M evolved cool stars. These extremely high-quality STIS UV echelle spectra are available from the HST archive and through the University of Colorado (http://casa.colorado.edu/ayres/ASTRAL/) portal and will enable investigations of a broad range of problems -- stellar, interstellar. and beyond -- for many years. In this current paper, we concentrate on producing a roadrnap to the very rich spectra of the two evolved M stars in the sample, the M3.4 giant Gamma Crucis (GaCrux) and the M2Iab supergiant Alpha Orionis (Betelgeuse) and illustrate the huge increase in coverage and quality that these spectra provide over that previously available from IUE and earlier HST observations. These roadmaps will facilitate the study of the spectra, outer atmospheres, and winds of not only these stars. but also numerous other cool, low-gravity stars and make a very interesting comparison to the already-available atlases of the K2III giant Arcturus.

  18. The Giant Planet Satellite Exospheres

    Science.gov (United States)

    McGrath, M. A.

    2014-12-01

    Exospheres are relatively common in the outer solar system among the moons of the gas giant planets. They span the range from very tenuous, surface-bounded exospheres (e.g., Rhea, Dione) to quite robust exospheres with exobase above the surface (e.g., Io, Triton), and include many intermediate cases (e.g., Europa, Ganymede, Enceladus). The exospheres of these moons exhibit an interesting variety of sources, from surface sputtering, to frost sublimation, to active plumes, and also well illustrate another common characteristic of the outer planet satellite exospheres, namely, that the primary species often exists both as a gas in atmosphere, and a condensate (frost or ice) on the surface. As described by Yelle et al. (1995) for Triton, "The interchange of matter between gas and solid phases on these bodies has profound effects on the physical state of the surface and the structure of the atmosphere." A brief overview of the exospheres of the outer planet satellites will be presented, including an inter-comparison of these satellites exospheres with each other, and with the exospheres of the Moon and Mercury.

  19. A giant thunderstorm on Saturn.

    Science.gov (United States)

    Fischer, G; Kurth, W S; Gurnett, D A; Zarka, P; Dyudina, U A; Ingersoll, A P; Ewald, S P; Porco, C C; Wesley, A; Go, C; Delcroix, M

    2011-07-06

    Lightning discharges in Saturn's atmosphere emit radio waves with intensities about 10,000 times stronger than those of their terrestrial counterparts. These radio waves are the characteristic features of lightning from thunderstorms on Saturn, which last for days to months. Convective storms about 2,000 kilometres in size have been observed in recent years at planetocentric latitude 35° south (corresponding to a planetographic latitude of 41° south). Here we report observations of a giant thunderstorm at planetocentric latitude 35° north that reached a latitudinal extension of 10,000 kilometres-comparable in size to a 'Great White Spot'-about three weeks after it started in early December 2010. The visible plume consists of high-altitude clouds that overshoot the outermost ammonia cloud layer owing to strong vertical convection, as is typical for thunderstorms. The flash rates of this storm are about an order of magnitude higher than previous ones, and peak rates larger than ten per second were recorded. This main storm developed an elongated eastward tail with additional but weaker storm cells that wrapped around the whole planet by February 2011. Unlike storms on Earth, the total power of this storm is comparable to Saturn's total emitted power. The appearance of such storms in the northern hemisphere could be related to the change of seasons, given that Saturn experienced vernal equinox in August 2009. ©2011 Macmillan Publishers Limited. All rights reserved

  20. Giant hepatocellular adenoma; case report

    Energy Technology Data Exchange (ETDEWEB)

    Pitella, F.A.; Coutinho, A.M.N.; Coura Filho, G.B.; Costa, P.L.A.; Ono, C.R.; Watanabe, T.; Sapienza, M.T.; Hironaka, F.; Cerri, G.G.; Buchpiguel, C.A. [Universidade de Sao Paulo (FM/USP), SP (Brazil). Inst. de Radiologia. Servico de Medicina Nuclear

    2008-07-01

    Full text: Introduction: Hepatocellular adenoma is a benign hepatic tumor identified mainly in women during fertility age, with estimated incidence of 4/1000 inhabitants. It is usually unique, well circumscribed, with or without a capsule, size varying from 1 to 30 cm, with possible central areas of necrosis and hemorrhage. Case Report: A 37-year-old female patient presenting with no comorbities, use of hormonal birth control pills for 18 years, a condition of reduction in the consistency of feces, increase in number of daily defecations, abdominal cramps, and a stuffed sensation after meals for two years. A palpable abdominal mass extending from the right hypochondriac to the right iliac fossa was noticed four months ago. A computerized tomography (CT) showed an extensive hepatic mass on the right which was considered, within the diagnostic hypotheses, hepatic adenomatosis, without ruling out secondary lesions. A hepatic scintillography with {sup 99m}Tc-DISIDA showed an extensive exophytic area from segment V to the right iliac fossa with arterialized blood flow and hepatocytic activity, as well as a hepatic nodule in segment VII with hepatocytic activity consistent with the hepatic adenomas hypothesis. The biopsy confirmed the hepatic adenoma diagnosis and the patient was submitted to a partial hepatectomy and cholecystectomy with good clinical evolution. Conclusion: Nuclear Medicine may supplement the assessment of hepatic nodules, including giant masses, thus suggesting new hypotheses and direction to therapeutic conduct. (author)

  1. Endoscopically removed giant submucosal lipoma

    Directory of Open Access Journals (Sweden)

    Jovanović Ivan

    2007-01-01

    Full Text Available Background. Although uncommon, giant submucosal colon lipomas merit attention as they are often presented with dramatic clinical features such as bleeding, acute bowel obstruction, perforation and sometimes may be mistaken for malignancy. There is a great debate in the literature as to how to treat them. Case report. A patient, 67-year old, was admitted to the Clinic due to a constipation over the last several months, increasing abdominal pain mainly localized in the left lower quadrant accompanied by nausea, vomiting and abdominal distension. Physical examination was unremarkable and the results of the detailed laboratory tests and carcinoembryonic antigen remained within normal limits. Colonoscopy revealed a large 10 cm long, and 4 to 5 cm in diameter, mobile lesion in his sigmoid colon. Conventional endoscopic ultrasound revealed 5 cm hyperechoic lesion of the colonic wall. Twenty MHz mini-probe examination showed that lesion was limited to the submucosa. Since polyp appeared too large for a single transaction, it was removed piecemeal. Once the largest portion of the polyp has been resected, it was relatively easy to place the opened snare loop around portions of the residual polyp. Endoscopic resection was carried out safely without complications. Histological examination revealed the common typical histological features of lipoma elsewhere. The patient remained stable and eventually discharged home. Four weeks later he suffered no recurrent symptoms. Conclusion. Colonic lipomas can be endoscopically removed safely eliminating unnecessary surgery.

  2. WSC-07: Evolving the Web Services Challenge

    NARCIS (Netherlands)

    Blake, M. Brian; Cheung, William K.W.; Jaeger, Michael C.; Wombacher, Andreas

    Service-oriented architecture (SOA) is an evolving architectural paradigm where businesses can expose their capabilities as modular, network-accessible software services. By decomposing capabilities into modular services, organizations can share their offerings at multiple levels of granularity

  3. Satcom access in the evolved packet core

    NARCIS (Netherlands)

    Cano, M.D.; Norp, A.H.J.; Popova, M.P.

    2012-01-01

    Satellite communications (Satcom) networks are increasingly integrating with terrestrial communications networks, namely Next Generation Networks (NGN). In the area of NGN the Evolved Packet Core (EPC) is a new network architecture that can support multiple access technologies. When Satcom is

  4. Acquisition: Acquisition of the Evolved SEASPARROW Missile

    National Research Council Canada - National Science Library

    2002-01-01

    .... The Evolved SEASPARROW Missile, a Navy Acquisition Category II program, is an improved version of the RIM-7P SEASPARROW missile that will intercept high-speed maneuvering, anti-ship cruise missiles...

  5. Surface-effect corrections for oscillation frequencies of evolved stars

    Science.gov (United States)

    Ball, W. H.; Gizon, L.

    2017-04-01

    Context. Accurate modelling of solar-like oscillators requires that modelled mode frequencies are corrected for the systematic shift caused by improper modelling of the near-surface layers, known as the surface effect. Several parametrizations of the surface effect are now available but they have not yet been systematically compared with observations of stars showing modes with mixed g- and p-mode character. Aims: We investigate how much additional uncertainty is introduced to stellar model parameters by our uncertainty about the functional form of the surface effect. At the same time, we test whether any of the parametrizations is significantly better or worse at modelling observed subgiants and low-luminosity red giants. Methods: We model six stars observed by Kepler that show clear mixed modes. We fix the input physics of the stellar models and vary the choice of surface correction between five parametrizations. Results: Models using a solar-calibrated power law correction consistently fit the observations more poorly than the other four corrections. Models with the remaining four corrections generally fit the observations about equally well, with the combined surface correction by Ball & Gizon perhaps being marginally superior. The fits broadly agree on the model parameters within about the 2σ uncertainties, with discrepancies between the modified Lorentzian and free power law corrections occasionally exceeding the 3σ level. Relative to the best-fitting values, the total uncertainties on the masses, radii and ages of the stars are all less than 2, 1 and 6 per cent, respectively. Conclusions: A solar-calibrated power law, as formulated by Kjeldsen et al., appears unsuitable for use with more evolved solar-like oscillators. Among the remaining surface corrections, the uncertainty in the model parameters introduced by the surface effects is about twice as large as the uncertainty in the individual fits for these six stars. Though the fits are thus somewhat less

  6. Cyberspace Operations: Influence Upon Evolving War Theory

    Science.gov (United States)

    2011-03-18

    St ra te gy R es ea rc h Pr oj ec t CYBERSPACE OPERATIONS: INFLUENCE UPON EVOLVING WAR THEORY BY COLONEL KRISTIN BAKER United States...DATES COVERED (From - To) 4. TITLE AND SUBTITLE Cyberspace Operations: Influence Upon Evolving War Theory 5a. CONTRACT NUMBER... Leadership 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S

  7. Evolving effective incremental SAT solvers with GP

    OpenAIRE

    Bader, Mohamed; Poli, R.

    2008-01-01

    Hyper-Heuristics could simply be defined as heuristics to choose other heuristics, and it is a way of combining existing heuristics to generate new ones. In a Hyper-Heuristic framework, the framework is used for evolving effective incremental (Inc*) solvers for SAT. We test the evolved heuristics (IncHH) against other known local search heuristics on a variety of benchmark SAT problems.

  8. On the origin of 'dividing lines' for late-type giants and supergiants

    Science.gov (United States)

    Rosner, R.; Musielak, Z. E.; Cattaneo, F.; Moore, R. L.; Suess, S. T.

    1995-03-01

    We show how a change in the nature of the stellar dyanmo can lead to a transition in the topological character of stellar magnetic fields of evolved stars, from being mainly closed on the blueward side of the giant tracks in the Hertzsprung-Russell (H-R) diagram to being mainly open on their redward side. If such a topological transition occurs, then these stars naturally segregate into two classes: those having hot coronae on the blueward side, and those having massive cool winds on the redward side, thus leading naturally to the so-called dividing lines.

  9. On the origin of 'dividing lines' for late-type giants and supergiants

    Science.gov (United States)

    Rosner, R.; Musielak, Z. E.; Cattaneo, F.; Moore, R. L.; Suess, S. T.

    1995-01-01

    We show how a change in the nature of the stellar dyanmo can lead to a transition in the topological character of stellar magnetic fields of evolved stars, from being mainly closed on the blueward side of the giant tracks in the Hertzsprung-Russell (H-R) diagram to being mainly open on their redward side. If such a topological transition occurs, then these stars naturally segregate into two classes: those having hot coronae on the blueward side, and those having massive cool winds on the redward side, thus leading naturally to the so-called dividing lines.

  10. Genetic profile of the giant cell glioblastoma.

    Science.gov (United States)

    Peraud, A; Watanabe, K; Schwechheimer, K; Yonekawa, Y; Kleihues, P; Ohgaki, H

    1999-02-01

    Giant cell glioblastoma is a rare glioblastoma variant characterized by the presence of large, bizarre, multinucleated giant cells. This glioblastoma subtype develops clinically de novo after a short clinical history and contains a high frequency of p53 mutations. In this study, we screened a series of 18 giant cell glioblastomas for additional genetic alterations. PCR-SSCP followed by DNA sequencing revealed PTEN mutations in 5 of 15 tumors (33%). Of these, two mutations were located in exon 5, two mutations in exon 6, and one mutation each in exons 1 and 9. Four mutations were point mutations and two mutations were deletions. One neoplasm contained two PTEN mutations (exons 5 and 6). None of the giant cell glioblastomas showed a homozygous deletion of PTEN orp16, or amplification of MDM2. Immunohistochemically, MDM2 overexpression was either not observed or detected in only a minor fraction of tumor cells. Differential PCR revealed EGFR amplification in only one of 17 tumors (6%). These results indicate that giant cell glioblastomas occupy a hybrid position, sharing with primary (de novo) glioblastomas a short clinical history, the absence of a less malignant precursor lesion and a 30% frequency of PTEN mutations. With secondary glioblastomas that develop through progression from low-grade astrocytomas, they have in common a younger patient age at manifestation and a high frequency (>70%) of p53 mutations.

  11. Asteroseismology of Red Giants and Galactic Archaeology

    Science.gov (United States)

    Hekker, Saskia

    From the oscillations in red-giant stars measured in time-series data it is possible to derive more accurate stellar parameters (e.g., mass, radius and age) as can be done using only single-epoch spectroscopy or photometry. These stellar parameters combined with chemical composition and the position, distance and velocity of the stars play an important role in studying the formation and evolution of the Milky Way. In this chapter we discuss some key physical phenomena that are at play in (red-giant) stars as well as some important phases in red-giant evolution. Subsequently, oscillation characteristics that are of importance for the determination of stellar parameters (as indicated above) of red-giant stars are introduced followed by a description of the main components of the Milky Way. Finally, the role red giants can play in creating a detailed observational picture of the Milky Way and deciphering the formation and evolution of the Milky Way is discussed.

  12. A GIANT SAMPLE OF GIANT PULSES FROM THE CRAB PULSAR

    Energy Technology Data Exchange (ETDEWEB)

    Mickaliger, M. B.; McLaughlin, M. A.; Lorimer, D. R.; Palliyaguru, N. [Department of Physics, West Virginia University, Morgantown, WV 26506 (United States); Langston, G. I. [National Radio Astronomy Observatory, Green Bank, WV 24944 (United States); Bilous, A. V. [Department of Astronomy, University of Virginia, P.O. Box 400325, Charlottesville, VA 22904 (United States); Kondratiev, V. I. [Netherlands Institute for Radio Astronomy (ASTRON), Postbus 2, 7990 AA Dwingeloo (Netherlands); Lyutikov, M. [Department of Physics, Purdue University, 525 Northwestern Avenue, West Lafayette, IN 47907-2036 (United States); Ransom, S. M. [National Radio Astronomy Observatory, Charlottesville, VA 22903 (United States)

    2012-11-20

    We observed the Crab pulsar with the 43 m telescope in Green Bank, WV over a timespan of 15 months. In total we obtained 100 hr of data at 1.2 GHz and seven hours at 330 MHz, resulting in a sample of about 95,000 giant pulses (GPs). This is the largest sample, to date, of GPs from the Crab pulsar taken with the same telescope and backend and analyzed as one data set. We calculated power-law fits to amplitude distributions for main pulse (MP) and interpulse (IP) GPs, resulting in indices in the range of 2.1-3.1 for MP GPs at 1.2 GHz and in the range of 2.5-3.0 and 2.4-3.1 for MP and IP GPs at 330 MHz. We also correlated the GPs at 1.2 GHz with GPs from the Robert C. Byrd Green Bank Telescope (GBT), which were obtained simultaneously at a higher frequency (8.9 GHz) over a span of 26 hr. In total, 7933 GPs from the 43 m telescope at 1.2 GHz and 39,900 GPs from the GBT were recorded during these contemporaneous observations. At 1.2 GHz, 236 (3%) MP GPs and 23 (5%) IP GPs were detected at 8.9 GHz, both with zero chance probability. Another 15 (4%) low-frequency IP GPs were detected within one spin period of high-frequency IP GPs, with a chance probability of 9%. This indicates that the emission processes at high and low radio frequencies are related, despite significant pulse profile shape differences. The 43 m GPs were also correlated with Fermi {gamma}-ray photons to see if increased pair production in the magnetosphere is the mechanism responsible for GP emission. A total of 92,022 GPs and 393 {gamma}-ray photons were used in this correlation analysis. No significant correlations were found between GPs and {gamma}-ray photons. This indicates that increased pair production in the magnetosphere is likely not the dominant cause of GPs. Possible methods of GP production may be increased coherence of synchrotron emission or changes in beaming direction.

  13. Evolvability Search: Directly Selecting for Evolvability in order to Study and Produce It

    DEFF Research Database (Denmark)

    Mengistu, Henok; Lehman, Joel Anthony; Clune, Jeff

    2016-01-01

    One hallmark of natural organisms is their significant evolvability, i.e.,their increased potential for further evolution. However, reproducing such evolvability in artificial evolution remains a challenge, which both reduces the performance of evolutionary algorithms and inhibits the study...... of evolvable digital phenotypes. Although some types of selection in evolutionary computation indirectly encourage evolvability, one unexplored possibility is to directly select for evolvability. To do so, we estimate an individual's future potential for diversity by calculating the behavioral diversity of its...... immediate offspring, and select organisms with increased offspring variation. While the technique is computationally expensive, we hypothesized that direct selection would better encourage evolvability than indirect methods. Experiments in two evolutionary robotics domains confirm this hypothesis: in both...

  14. Giant bladder lithiasis: case report and bibliographic review.

    Science.gov (United States)

    Gallego Vilar, Daniel; Beltran Persiva, José; Pérez Mestre, Mateo; Povo Martin, Iván José; Miralles Aguado, Jaume; Garau Perelló, Carmen; De Francia, Jose Antonio

    2011-05-01

    Urinary lithiasis is a very frequent urological disease but bladder lithiasis is very uncommon.Patients usually refer voiding symptoms and hematuria. The diagnosis is made after imaging tests. We report a clinical case describing a giant bladder stone and perform a bibliographic review. A 43 year old man with the diagnosis of giant bladder stone (more than 10 cm diameter). We searched Medline using the terms: giant bladder stone, giant bladder lithiasis, bladder lithiasis, giant bladder lithiasis. We made the diagnosis of giant bladder stone after a simple kidney, ureter and bladder (KUB) X Ray. The treatment for this patient was a cystolithotomy. We found more than 230 reports at Medline and chose the most referred ones and the last 10 years reports. Giant bladder lithiasis is a very rare pathology. The gold standard for diagnosis is cystoscopy but sometimes with a KUB Xray or an ultrasound is enough. Because of its size, cistolitotomy is the correct treatment for giant bladder stone.

  15. Compositional constraints on giant planet formation

    Science.gov (United States)

    Owen, Tobias; Encrenaz, Therese

    2006-10-01

    Using Ockham's razor as a guide, we have tried to find the simplest model for the formation of giant planets that can explain current observations of atmospheric composition. While this "top-down" approach is far from sufficient to define such models, it establishes a set of boundary conditions whose satisfaction is necessary. Using Jupiter as the prototype, we find that a simple model for giant planet formation that begins with a solar nebula of uniform composition and relies on accretion of low temperature icy planetesimals plus collapse of surrounding solar nebula gas supplies that satisfaction. We compare the resulting predictions of elemental abundances and isotope ratios in the atmospheres of the other giants with those from contrasting models and suggest some key measurements to make further progress.

  16. On the shape of giant soap bubbles.

    Science.gov (United States)

    Cohen, Caroline; Darbois Texier, Baptiste; Reyssat, Etienne; Snoeijer, Jacco H; Quéré, David; Clanet, Christophe

    2017-03-07

    We study the effect of gravity on giant soap bubbles and show that it becomes dominant above the critical size [Formula: see text], where [Formula: see text] is the mean thickness of the soap film and [Formula: see text] is the capillary length ([Formula: see text] stands for vapor-liquid surface tension, and [Formula: see text] stands for the liquid density). We first show experimentally that large soap bubbles do not retain a spherical shape but flatten when increasing their size. A theoretical model is then developed to account for this effect, predicting the shape based on mechanical equilibrium. In stark contrast to liquid drops, we show that there is no mechanical limit of the height of giant bubble shapes. In practice, the physicochemical constraints imposed by surfactant molecules limit the access to this large asymptotic domain. However, by an exact analogy, it is shown how the giant bubble shapes can be realized by large inflatable structures.

  17. Hepatic Giant Cell Arteritis and Polymyalgia Rheumatica

    Directory of Open Access Journals (Sweden)

    Donald R Duerksen

    1994-01-01

    Full Text Available Polymyalgia rheumatica (PMR is a clinical syndrome of the elderly characterized by malaise, proximal muscle aching and stiffness, low grade fever, elevated erythrocyte sedimentation rare and the frequent association with temporal giant cell arteritis. The authors describe a case of PMR associated with hepatic giant cell arteritis. This lesion has been described in two other clinical reports. The distribution of the arteritis may be patchy; in this report, diagnosis was made with a wedge biopsy performed after an initial nonspecific percutaneous liver biopsy. The authors review the spectrum of liver involvement in PMR and giant cell arteritis. Hepatic abnormalities respond to systemic corticosteroids, and patients with hepatic arteritis have a good prognosis.

  18. Enhanced recovery after giant ventral hernia repair

    DEFF Research Database (Denmark)

    Jensen, K K; Brøndum, T L; Harling, H.

    2016-01-01

    PURPOSE: Giant ventral hernia repair is associated with a high risk of postoperative morbidity and prolonged length of stay (LOS). Enhanced recovery (ERAS) measures have proved to lead to decreased morbidity and LOS after various surgical procedures, but never after giant hernia repair. The current...... study prospectively examined the results of implementation of an ERAS pathway including high-dose preoperative glucocorticoid, and compared the outcome with patients previously treated according to standard care (SC). METHODS: Consecutive patients who underwent giant ventral hernia repair were included...... was 0.92. There were no differences when comparing readmission (5 vs. 2, P = 0.394), postoperative complications (7 vs. 4, P = 0. 458), or reoperation (5 vs. 1, P = 0.172) in ERAS versus controls. CONCLUSIONS: The current study suggests that an ERAS pathway including preoperative high...

  19. Giant fibroepithelial polyp of the ureter.

    Science.gov (United States)

    Gupta, Mayank; Roy, Sanjeet; Wann, Cornerstone; Eapen, Anu

    2017-04-07

    Giant fibroepithelial polyp is a rare cause of ureteric/ureteropelvic junction (UPJ) obstruction. We report a rare case of giant fibroepithelial polyp in a 32-year-old woman involving the whole length of the ureter, reaching up to the UPJ which was clinically and radiologically considered to be urothelial carcinoma. Frozen section showed a polypoid lesion lined by urothelium with no evidence of dysplasia or malignancy. Subsequently, nephroureterectomy was done as there was marked renal hydronephrosis and it was impossible to separate the polyp from the wall of the ureter. Histopathological examination and immunohistochemistry confirmed the diagnosis of giant fibroepithelial polyp, ruling out malignancy. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  20. Evolved atmospheric entry corridor with safety factor

    Science.gov (United States)

    Liang, Zixuan; Ren, Zhang; Li, Qingdong

    2018-02-01

    Atmospheric entry corridors are established in previous research based on the equilibrium glide condition which assumes the flight-path angle to be zero. To get a better understanding of the highly constrained entry flight, an evolved entry corridor that considers the exact flight-path angle is developed in this study. Firstly, the conventional corridor in the altitude vs. velocity plane is extended into a three-dimensional one in the space of altitude, velocity, and flight-path angle. The three-dimensional corridor is generated by a series of constraint boxes. Then, based on a simple mapping method, an evolved two-dimensional entry corridor with safety factor is obtained. The safety factor is defined to describe the flexibility of the flight-path angle for a state within the corridor. Finally, the evolved entry corridor is simulated for the Space Shuttle and the Common Aero Vehicle (CAV) to demonstrate the effectiveness of the corridor generation approach. Compared with the conventional corridor, the evolved corridor is much wider and provides additional information. Therefore, the evolved corridor would benefit more to the entry trajectory design and analysis.

  1. Histological Structure of Gills of Giant Mudskipper (Periophthalmodon schlosseri)

    OpenAIRE

    Yudistira, Danang Bagus; Nurliani, Anni; Santoso, Heri Budi

    2012-01-01

    Giant mudskipper (Periophthalmodon schlosseri) is one of gobiidae members that does air-breathing and lives on intertidal zone with mangrove habitat. The ability of giant mudskipper to adapt with water to land environment is due to its gill histological structure. The objective of the present study was to observe the structure of giant mudskipper’s gill and to identify sort of cells and its distributions descriptively. The gills of three adult giant mudskippers were taken and processed to his...

  2. LITHIUM-RICH GIANTS IN GLOBULAR CLUSTERS

    Energy Technology Data Exchange (ETDEWEB)

    Kirby, Evan N.; Cohen, Judith G. [California Institute of Technology, 1200 E. California Boulevard, MC 249-17, Pasadena, CA 91125 (United States); Guhathakurta, Puragra [UCO/Lick Observatory and Department of Astronomy and Astrophysics, University of California, 1156 High Street, Santa Cruz, CA 95064 (United States); Zhang, Andrew J. [The Harker School, 500 Saratoga Avenue, San Jose, CA 95129 (United States); Hong, Jerry [Palo Alto High School, 50 Embarcadero Road, Palo Alto, CA, 94301 (United States); Guo, Michelle [Stanford University, 450 Serra Mall, Stanford, CA 94305 (United States); Guo, Rachel [Irvington High School, 41800 Blacow Road, Fremont, CA 94538 (United States); Cunha, Katia [Observatório Nacional, São Cristóvão Rio de Janeiro (Brazil)

    2016-03-10

    Although red giants deplete lithium on their surfaces, some giants are Li-rich. Intermediate-mass asymptotic giant branch (AGB) stars can generate Li through the Cameron–Fowler conveyor, but the existence of Li-rich, low-mass red giant branch (RGB) stars is puzzling. Globular clusters are the best sites to examine this phenomenon because it is straightforward to determine membership in the cluster and to identify the evolutionary state of each star. In 72 hours of Keck/DEIMOS exposures in 25 clusters, we found four Li-rich RGB and two Li-rich AGB stars. There were 1696 RGB and 125 AGB stars with measurements or upper limits consistent with normal abundances of Li. Hence, the frequency of Li-richness in globular clusters is (0.2 ± 0.1)% for the RGB, (1.6 ± 1.1)% for the AGB, and (0.3 ± 0.1)% for all giants. Because the Li-rich RGB stars are on the lower RGB, Li self-generation mechanisms proposed to occur at the luminosity function bump or He core flash cannot explain these four lower RGB stars. We propose the following origin for Li enrichment: (1) All luminous giants experience a brief phase of Li enrichment at the He core flash. (2) All post-RGB stars with binary companions on the lower RGB will engage in mass transfer. This scenario predicts that 0.1% of lower RGB stars will appear Li-rich due to mass transfer from a recently Li-enhanced companion. This frequency is at the lower end of our confidence interval.

  3. Exploring the Ice Giants with JWST

    Science.gov (United States)

    Orton, Glenn S.; Fletcher, Leigh; Hammel, Heidi B.; Melin, Henrik; Guerlet, Sandrine; Greathouse, Thomas K.; Irwin, Patrick GJ

    2017-06-01

    The Ice Giants Uranus and Neptune are among the least-explored environments in our Solar System, having been visited only once, by Voyager 2 in 1986 and 1989, respectively. Their bulk properties and composition, intermediate between the hydrogen-rich gas giants and the smaller terrestrial worlds, make them representative of a planetary class that may be commonplace in other planetary systems. Furthermore, their small angular diameter, low atmospheric temperatures, and dynamic and ever-changing atmospheres make them tantalising infrared targets for JWST. This presentation will reveal the scientific rationale and requirements for a long-term program of JWST spectroscopic mapping of these two worlds. Specifically, the MIRI instrument can be used to determine the 3-dimensional temperature structure to understand (i) seasonal atmospheric circulation from the equator to the poles, (ii) the relation between temperatures, visible atmospheric banding and storm phenomena; and (iii) to discover the unknown circulations and wave phenomena shaping their middle atmospheres. JWST spectra will also allow us to search for and map chemical species produced from photochemistry (e.g., hydrocarbons derived from methane photolysis), from vertical mixing (e.g., disequilibrium species), and from external sources (e.g., HCN and oxygen compounds delivered by comets, ring rain and interplanetary dust). Furthermore, near-infrared imaging and spectroscopy with NIRCAM and NIRSpec will provide detailed characterisations of ice-giant cloud and haze formation and their evolution with time, as well as revealing how auroral processes (observed via H3+ emission) influence the middle atmosphere. JWST will not only enable intercomparison of these atmospheric processes on two very different worlds (Uranus with its extreme tilt and sluggish mixing; Neptune with its powerful internal heat source), but also mature our understanding of how ice giant phenomena compare to both gas giant and terrestrial

  4. Lineage-specific evolution of bitter taste receptor genes in the giant and red pandas implies dietary adaptation.

    Science.gov (United States)

    Shan, Lei; Wu, Qi; Wang, Le; Zhang, Lei; Wei, Fuwen

    2017-11-23

    Bitter taste receptor genes (TAS2Rs) mediate bitterness perception in mammals. It is believed that these genes evolved in response to species-specific diets. The giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens styani) in the order Carnivora are specialized herbivores with an almost exclusive bamboo diet (>90% bamboo). Because bamboo is full of bitter tasting compounds, we hypothesized that adaptive evolution have occurred at TAS2R genes in giant and red pandas throughout the course of their dietary shift. Here, we characterized 195 TAS2Rs in nine Carnivora species and examined selective pressures on these genes. We found that both pandas harbour more putative functional TAS2Rs than other carnivores, and pseudogenized TAS2Rs in the giant panda are different from the red panda. The purifying selection on TAS2R1, TAS2R9 and TAS2R38 in the giant panda, and TAS2R62 in the red panda, has been strengthened throughout the course of adaptation to bamboo diet, while selective constraint on TAS2R4 and TAS2R38 in the red panda is relaxed. Remarkably, a few positively selected sites has been lineage-specifically detected on TAS2R42 in the giant panda. These results suggest an adaptive response in both pandas to a dietary shift from carnivory to herbivory, and TAS2Rs evolved independently in the two pandas. Our findings provide new insights into the molecular basis of mammalian sensory evolution and the process of adaptation to new ecological niches. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  5. Probing giant magnetoresistance with THz spectroscopy

    DEFF Research Database (Denmark)

    Jin, Zuanming; Tkach, Alexander; Casper, Frederick

    2014-01-01

    We observe a giant magnetoresistance effect in CoFe/Cu-based multistack using THz time-domain spectroscopy. The magnetic field-dependent dc conductivity, electron scattering time, as well as spin-asymmetry parameter of the structure are successfully determined. © 2014 OSA.......We observe a giant magnetoresistance effect in CoFe/Cu-based multistack using THz time-domain spectroscopy. The magnetic field-dependent dc conductivity, electron scattering time, as well as spin-asymmetry parameter of the structure are successfully determined. © 2014 OSA....

  6. Sum rules and giant resonances in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Lipparini, E.; Stringari, S.

    1989-04-01

    The formalism of sum rules is developed and employed to investigate various giant resonances in nuclei. Particular emphasis is given to the role of surface effects which are shown to play a crucial role in the propagation of isoscalar as well as isovector collective modes. Sum rules for non-Hermitian operators, in particular for charge exchange reactions, are derived using the formalism of the dynamic polarizability. Several sum rules for investigating magnetic excitations, the structure of the transition density and the role of the nuclear deformation and of temperature on giant resonances are also presented and discussed.

  7. Neglected Giant Scalp Basal Cell Carcinoma

    Directory of Open Access Journals (Sweden)

    Anne Kristine Larsen, MD

    2014-03-01

    Full Text Available Summary: Rarely, basal cell carcinoma grows to a giant size, invading the underlying deep tissue and complicating the treatment and reconstruction modalities. A giant basal cell carcinoma on the scalp is in some cases treated with a combination of surgery and radiation therapy, resulting in local control, a satisfactory long-term cosmetic and functional result. We present a case with a neglected basal cell scalp carcinoma, treated with wide excision and postoperative radiotherapy, reconstructed with a free latissimus dorsi flap. The cosmetic result is acceptable and there is no sign of recurrence 1 year postoperatively.

  8. Neglected giant scalp Basal cell carcinoma

    DEFF Research Database (Denmark)

    Larsen, Anne Kristine; El-Charnoubi, Waseem-Asim Ghulam; Gehl, Julie

    2014-01-01

    SUMMARY: Rarely, basal cell carcinoma grows to a giant size, invading the underlying deep tissue and complicating the treatment and reconstruction modalities. A giant basal cell carcinoma on the scalp is in some cases treated with a combination of surgery and radiation therapy, resulting in local...... control, a satisfactory long-term cosmetic and functional result. We present a case with a neglected basal cell scalp carcinoma, treated with wide excision and postoperative radiotherapy, reconstructed with a free latissimus dorsi flap. The cosmetic result is acceptable and there is no sign of recurrence...

  9. Kepler Asteroseismology of Red-giant Stars

    DEFF Research Database (Denmark)

    Christensen-Dalsgaard, J.

    2012-01-01

    The Kepler mission, launched in March 2009, has revolutionized asteroseismology, providing detailed observations of thousands of stars. This has allowed in-depth analyses of stars ranging from compact hot subdwarfs to red giants, and including the detection of solar-like oscillations in hundreds...... of stars on or near the main sequence. Here I mainly consider solar-like oscillations in red giants, where Kepler observations are yielding results of a perhaps unexpected richness. In addition to giving a brief overview of the observational and numerical results for these stars, I present a simple...

  10. The interior structure of the giant planets

    Science.gov (United States)

    Zharkov, V. N.

    1991-12-01

    An overview of the principal ideas and data pertaining to the construction of models of the interior structure of Jupiter, Saturn, Uranus, and Neptune is presented. Topics discussed include: the concept of Jupiter and Saturn as planets with hydrogenic crusts; the theory of the figure of rotating planets in hydrostatic equilibrium; a gas-liquid dynamic model of the giant planets; analysis of observational data; abundances of elements and groups of cosmochemical substances; equations of state; and the role of Jupiter in the formation of the earth and the giant planets.

  11. Photon decay of giant multipole resonances

    Energy Technology Data Exchange (ETDEWEB)

    Bertrand, F.E.; Beene, J.R.

    1990-01-01

    A brief review of the excitation of giant multipole resonances via Coulomb excitation is given which emphasizes the very large cross sections that can be realized through this reaction for both isoscalar and isovector resonances. Discussion and results where available, are provided for the measurement of the photon decay of one and two phonon giant resonances. It is pointed out throughout the presentation that the use of E1 photons as a tag'' provides a means to observe weakly excited resonances that cannot be observed in the shingles spectra. 26 refs., 16 figs., 1 tab.

  12. Giant Condyloma Acuminatum: A Surgical Riddle

    Directory of Open Access Journals (Sweden)

    Shukla

    2016-08-01

    Full Text Available Giant condyloma acuminatum (GCA commonly known as Buschke-Lowenstein tumor (BLT is a rare sexually transmitted disease, which is always preceded by condyloma accuminata and linked to human papillomavirus (HPV. Most commonly affected sites are male and female genitalia, anal and perianal regions. Giant condyloma acuminatum is well-known as slow growing but locally destructive with a high rate of recurrence and increased frequency of malignant transformation. Surgical management is considered to be the best among all the options.

  13. Interactively Evolving Compositional Sound Synthesis Networks

    DEFF Research Database (Denmark)

    Jónsson, Björn Þór; Hoover, Amy K.; Risi, Sebastian

    2015-01-01

    While the success of electronic music often relies on the uniqueness and quality of selected timbres, many musicians struggle with complicated and expensive equipment and techniques to create their desired sounds. Instead, this paper presents a technique for producing novel timbres that are evolved......, CPPNs can theoretically compute any function and can build on those present in traditional synthesizers (e.g. square, sawtooth, triangle, and sine waves functions) to produce completely novel timbres. Evolved with NeuroEvolution of Augmenting Topologies (NEAT), the aim of this paper is to explore...... the space of potential sounds that can be generated through such compositional sound synthesis networks (CSSNs). To study the effect of evolution on subjective appreciation, participants in a listener study ranked evolved timbres by personal preference, resulting in preferences skewed toward the first...

  14. Quantifying evolvability in small biological networks

    Energy Technology Data Exchange (ETDEWEB)

    Nemenman, Ilya [Los Alamos National Laboratory; Mugler, Andrew [COLUMBIA UNIV; Ziv, Etay [COLUMBIA UNIV; Wiggins, Chris H [COLUMBIA UNIV

    2008-01-01

    The authors introduce a quantitative measure of the capacity of a small biological network to evolve. The measure is applied to a stochastic description of the experimental setup of Guet et al. (Science 2002, 296, pp. 1466), treating chemical inducers as functional inputs to biochemical networks and the expression of a reporter gene as the functional output. The authors take an information-theoretic approach, allowing the system to set parameters that optimise signal processing ability, thus enumerating each network's highest-fidelity functions. All networks studied are highly evolvable by the measure, meaning that change in function has little dependence on change in parameters. Moreover, each network's functions are connected by paths in the parameter space along which information is not significantly lowered, meaning a network may continuously change its functionality without completely losing it along the way. This property further underscores the evolvability of the networks.

  15. Giant Panda habitat selection in the Foping Nature Reserve, China

    NARCIS (Netherlands)

    Liu, X.; Toxopeus, A.G.; Skidmore, A.K.; Shao, X.; Dang, D.; Wang, T.; Prins, H.H.T.

    2005-01-01

    Little is known about habitat selection of the giant panda (Ailuropoda melanoleuca), especially about the relationship between giant panda presence and bamboo and tree structures. We presented data on giant panda habitat use and selection in Foping Nature Reserve (NR), China. We used 1,066

  16. Observing giant panda habitat and forage abundance from space

    NARCIS (Netherlands)

    Wang, T.

    2009-01-01

    Giant pandas are obligate bamboo grazers. The bamboos favoured by giant pandas are typical forest understorey plants. Therefore, the availability and abundance of understorey bamboo is a key factor in determining the quantity and quality of giant panda food resources. However, there is little or

  17. Giant-cell lesions of the facial bones

    Energy Technology Data Exchange (ETDEWEB)

    Som, P.M.; Lawson, W.; Cohen, B.A.

    1983-04-01

    Giant-cell lesions of the paranasal sinuses, including the giant-cell reparative granuloma, the brown tumor of hyperparathyroidism, the true giant-cell tumor, cherubism, and the aneurysmal bone cyst, are uncommon entities. Plain radiographic and computed-tomographic studies of these lesions are described and the differential diagnosis is discussed.

  18. Giant urinary bladder calculus: Case report | Otieno | East African ...

    African Journals Online (AJOL)

    A vertical calculus weighing more than 100 g is categorised as a giant urinary bladder stone. Giant urinary bladder stones are very rare and very few cases have been reported in English literature and only one case from Africa. This is a case report of a patient with a giant urinary bladder calculus presenting as a rectal ...

  19. Patient with Benign Prostatic Hypertrophy and Two Giant Stones in ...

    African Journals Online (AJOL)

    Giant urinary bladder stones are very rare; very few cases have been reported in English literature and only one case from Africa. Multiple giant bladder stones are extremely rare; no single case report has been found documenting this occasion. This report presents a patient of benign prostatic hypertrophy with two giant ...

  20. Staged Closure of Giant Omphalocele using Synthetic Mesh

    OpenAIRE

    Lalit Parida; Kamalesh Pal; Hussah Al Buainain; Hossam Elshafei

    2014-01-01

    Giant omphalocele is difficult to manage and is associated with a poor outcome. A male newborn presented to our hospital with a giant omphalocele. We performed a staged closure of giant omphalocele using synthetic mesh to construct a silo and then mesh abdominoplasty in the neonatal period that led to a successful outcome within a reasonable period of hospital stay.

  1. Evolution of evolvability in gene regulatory networks.

    Directory of Open Access Journals (Sweden)

    Anton Crombach

    Full Text Available Gene regulatory networks are perhaps the most important organizational level in the cell where signals from the cell state and the outside environment are integrated in terms of activation and inhibition of genes. For the last decade, the study of such networks has been fueled by large-scale experiments and renewed attention from the theoretical field. Different models have been proposed to, for instance, investigate expression dynamics, explain the network topology we observe in bacteria and yeast, and for the analysis of evolvability and robustness of such networks. Yet how these gene regulatory networks evolve and become evolvable remains an open question. An individual-oriented evolutionary model is used to shed light on this matter. Each individual has a genome from which its gene regulatory network is derived. Mutations, such as gene duplications and deletions, alter the genome, while the resulting network determines the gene expression pattern and hence fitness. With this protocol we let a population of individuals evolve under Darwinian selection in an environment that changes through time. Our work demonstrates that long-term evolution of complex gene regulatory networks in a changing environment can lead to a striking increase in the efficiency of generating beneficial mutations. We show that the population evolves towards genotype-phenotype mappings that allow for an orchestrated network-wide change in the gene expression pattern, requiring only a few specific gene indels. The genes involved are hubs of the networks, or directly influencing the hubs. Moreover, throughout the evolutionary trajectory the networks maintain their mutational robustness. In other words, evolution in an alternating environment leads to a network that is sensitive to a small class of beneficial mutations, while the majority of mutations remain neutral: an example of evolution of evolvability.

  2. How the first biopolymers could have evolved.

    Science.gov (United States)

    Abkevich, V I; Gutin, A M; Shakhnovich, E I

    1996-01-01

    In this work, we discuss a possible origin of the first biopolymers with stable unique structures. We suggest that at the prebiotic stage of evolution, long organic polymers had to be compact to avoid hydrolysis and had to be soluble and thus must not be exceedingly hydrophobic. We present an algorithm that generates such sequences for model proteins. The evolved sequences turn out to have a stable unique structure, into which they quickly fold. This result illustrates the idea that the unique three-dimensional native structures of first biopolymers could have evolved as a side effect of nonspecific physicochemical factors acting at the prebiotic stage of evolution. PMID:8570645

  3. Evolving Intelligent Systems Methodology and Applications

    CERN Document Server

    Angelov, Plamen; Kasabov, Nik

    2010-01-01

    From theory to techniques, the first all-in-one resource for EIS. There is a clear demand in advanced process industries, defense, and Internet and communication (VoIP) applications for intelligent yet adaptive/evolving systems. Evolving Intelligent Systems is the first self- contained volume that covers this newly established concept in its entirety, from a systematic methodology to case studies to industrial applications. Featuring chapters written by leading world experts, it addresses the progress, trends, and major achievements in this emerging research field, with a strong emphasis on th

  4. Empirically Calibrated Asteroseismic Masses and Radii for Red Giants in the Kepler Fields

    Science.gov (United States)

    Pinsonneault, Marc; Elsworth, Yvonne; Silva Aguirre, Victor; Chaplin, William J.; Garcia, Rafael A.; Hekker, Saskia; Holtzman, Jon; Huber, Daniel; Johnson, Jennifer; Kallinger, Thomas; Mosser, Benoit; Mathur, Savita; Serenelli, Aldo; Shetrone, Matthew; Stello, Dennis; Tayar, Jamie; Zinn, Joel; APOGEE Team, KASC Team, APOKASC Team

    2018-01-01

    We report on the joint asteroseismic and spectroscopic properties of a sample of 6048 evolved stars in the fields originally observed by the Kepler satellite. We use APOGEE spectroscopic data taken from Data Release 13 of the Sloan Digital Sky Survey, combined with asteroseismic data analyzed by members of the Kepler Asteroseismic Science Consortium. With high statistical significance, the different pipelines do not have relative zero points that are the same as the solar values, and red clump stars do not have the same empirical relative zero points as red giants. We employ theoretically motivated corrections to the scaling relation for the large frequency spacing, and adjust the zero point of the frequency of maximum power scaling relation to be consistent with masses and radii for members of star clusters. The scatter in calibrator masses is consistent with our error estimation. Systematic and random mass errors are explicitly separated and identified. The measurement scatter, and random uncertainties, are three times larger for red giants where one or more technique failed to return a value than for targets where all five methods could do so, and this is a substantial fraction of the sample (20% of red giants and 25% of red clump stars). Overall trends and future prospects are discussed.

  5. The effect of close-in giant planets' evolution on tidal-induced migration of exomoons

    Science.gov (United States)

    Alvarado-Montes, J. A.; Zuluaga, Jorge I.; Sucerquia, Mario

    2017-11-01

    Hypothetical exomoons around close-in giant planets may migrate inwards and/or outwards in virtue of the interplay of the star, planet and moon tidal interactions. These processes could be responsible for the disruption of lunar systems, the collision of moons with planets or could provide a mechanism for the formation of exorings. Several models have been developed to determine the fate of exomoons when subjected to the tidal effects of their host planets. None of them has taken into account the key role that planetary evolution could play in this process. In this paper, we put together numerical models of exomoon's tidal-induced orbital evolution, results of planetary evolution and interior structure models to study the final fate of exomoons around evolving close-in gas giants. We have found that planetary evolution significantly affects not only the time-scale of exomoon migration but also its final fate. Thus, if any change in planetary radius, internal mass distribution and rotation occurs in time-scales lower or comparable to orbital evolution, exomoon may only migrate outwards and prevent tidal disruption or a collision with the planet. If exomoons are discovered in the future around close-in giant planets, our results may contribute to constrain planetary evolution and internal structure models.

  6. An outburst powered by the merging of two stars inside the envelope of a giant

    Science.gov (United States)

    Hillel, Shlomi; Schreier, Ron; Soker, Noam

    2017-11-01

    We conduct 3D hydrodynamical simulations of energy deposition into the envelope of a red giant star as a result of the merger of two close main sequence stars or brown dwarfs, and show that the outcome is a highly non-spherical outflow. Such a violent interaction of a triple stellar system can explain the formation of `messy', I.e. lacking any kind of symmetry, planetary nebulae and similar nebulae around evolved stars. We do not simulate the merging process, but simply assume that after the tight binary system enters the envelope of the giant star the interaction with the envelope causes the two components, stars or brown dwarfs, to merge and liberate gravitational energy. We deposit the energy over a time period of about 9 h, which is about 1 per cent of the the orbital period of the merger product around the centre of the giant star. The ejection of the fast hot gas and its collision with previously ejected mass are very likely to lead to a transient event, I.e. an intermediate luminosity optical transient.

  7. Preface: evolving rotifers, evolving science: Proceedings of the XIV International Rotifer Symposium

    Czech Academy of Sciences Publication Activity Database

    Devetter, Miloslav; Fontaneto, D.; Jersabek, Ch.D.; Welch, D.B.M.; May, L.; Walsh, E.J.

    2017-01-01

    Roč. 796, č. 1 (2017), s. 1-6 ISSN 0018-8158 Institutional support: RVO:60077344 Keywords : evolving rotifers * 14th International Rotifer Symposium * evolving science Subject RIV: EG - Zoology OBOR OECD: Zoology Impact factor: 2.056, year: 2016

  8. Thermal and Evolved-Gas Analyzer Illustration

    Science.gov (United States)

    2008-01-01

    This is a computer-aided drawing of the Thermal and Evolved-Gas Analyzer, or TEGA, on NASA's Phoenix Mars Lander. The Phoenix Mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development is by Lockheed Martin Space Systems, Denver.

  9. Apollo 16 Evolved Lithology Sodic Ferrogabbro

    Science.gov (United States)

    Zeigler, Ryan; Jolliff, B. L.; Korotev, R. L.

    2014-01-01

    Evolved lunar igneous lithologies, often referred to as the alkali suite, are a minor but important component of the lunar crust. These evolved samples are incompatible-element rich samples, and are, not surprisingly, most common in the Apollo sites in (or near) the incompatible-element rich region of the Moon known as the Procellarum KREEP Terrane (PKT). The most commonly occurring lithologies are granites (A12, A14, A15, A17), monzogabbro (A14, A15), alkali anorthosites (A12, A14), and KREEP basalts (A15, A17). The Feldspathic Highlands Terrane is not entirely devoid of evolved lithologies, and rare clasts of alkali gabbronorite and sodic ferrogabbro (SFG) have been identified in Apollo 16 station 11 breccias 67915 and 67016. Curiously, nearly all pristine evolved lithologies have been found as small clasts or soil particles, exceptions being KREEP basalts 15382/6 and granitic sample 12013 (which is itself a breccia). Here we reexamine the petrography and geochemistry of two SFG-like particles found in a survey of Apollo 16 2-4 mm particles from the Cayley Plains 62283,7-15 and 62243,10-3 (hereafter 7-15 and 10-3 respectively). We will compare these to previously reported SFG samples, including recent analyses on the type specimen of SFG from lunar breccia 67915.

  10. (RPS16) from the Giant Panda

    African Journals Online (AJOL)

    USER

    2010-04-12

    Apr 12, 2010 ... Eukaryotic ribosomes are intricate structures containing three to four rRNAs and 70 to 80 distinct ... sequence of the RPS16 from DNA from the skeleton muscle of the Giant Panda and then analyzed the sequence characteristics of the protein encoded by the cDNA and compared it with those of human and ...

  11. Nitrogen depletion in field red giants

    DEFF Research Database (Denmark)

    Masseron, T.; Lagarde, N.; Miglio, A.

    2017-01-01

    , the behaviour of nitrogen data along the evolution confirms the existence of non-canonical extramixing on the red giant branch (RGB) for all low-mass stars in the field. But more surprisingly, the data indicate that nitrogen has been depleted between the RGB tip and the red clump. This may suggest that some...

  12. Giant omental lipoblastoma and CD56 expression

    Directory of Open Access Journals (Sweden)

    Go Miyano

    2013-01-01

    Full Text Available We report a case of giant omental lipoblastoma in a 13-month-old boy, which was treated successfully by total excision. Tumor cells were positive for S100, CD34 and CD56. This is the first report of lipoblastoma expressing CD56, a fact that could be used to differentiate lipoblastoma from liposarcoma.

  13. THE GIANT TORTOISE POPULATION OF ALDABRA (CRYPTODIRA ...

    African Journals Online (AJOL)

    Crude estimates of mortality and reproductive rates are also given. INTRODUCTION. Until the advent of man, giant tortoise populations existed on many islands of the western. Indian Ocean, including the Seychelles and Mauritius. They also occurred on the Galapagos. Archipelago in the Pacific. As a result of man's activity ...

  14. Giant viruses of amoebas: an update

    Directory of Open Access Journals (Sweden)

    Sarah eAherfi

    2016-03-01

    Full Text Available During the 12 past years, five new or putative virus families encompassing several members, namely Mimiviridae, Marseilleviridae, pandoraviruses, faustoviruses, and virophages were described. In addition, Pithovirus sibericum and Mollivirus sibericum represent type strains of putative new giant virus families. All these viruses were isolated using amoebal coculture methods. These giant viruses were linked by phylogenomic analyses to other large DNA viruses. They were then proposed to be classified in a new viral order, the Megavirales, on the basis of their common origin, as shown by a set of ancestral genes encoding key viral functions, a common virion architecture, and shared major biological features including replication inside cytoplasmic factories. Megavirales is increasingly demonstrated to stand in the tree of life aside Bacteria, Archaea and Eukarya, and the megavirus ancestor is suspected to be as ancient as cellular ancestors. In addition, giant amoebal viruses are visible under a light microscope and display many phenotypic and genomic features not found in other viruses, while they share other characteristics with parasitic microbes. Moreoever, these organisms appear to be common inhabitants of our biosphere, and mimiviruses and marseilleviruses were isolated from human samples and associated to diseases. In the present review, we describe the main features and recent findings on these giant amoebal viruses and virophages.

  15. Star cluster disruption by giant molecular clouds

    NARCIS (Netherlands)

    Gieles, M.; Portegies Zwart, S.F.; BAumgardt, H.; Athanassoula, E.; Lamers, H.J.G.L.M.; Sipior, M.; Leenaarts, J.

    2006-01-01

    We investigate encounters between giant molecular clouds (GMCs) and star clusters. We propose a single expression for the energy gain of a cluster due to an encounter with a GMC, valid for all encounter distances and GMC properties. This relation is verified with N-body simulations of cluster–GMC

  16. Inside view of a giant proton pump

    NARCIS (Netherlands)

    Brandt, U.

    2013-01-01

    Inner workings: The X-ray crystal structure of the entire bacterial complex I at 3.3 A resolution offers fascinating insights into a giant 536 kDa molecular machine. The respiratory chain complex seems to employ unique mechanisms of energetic coupling that are entirely different from those found in

  17. (RPL37A) from the giant panda

    African Journals Online (AJOL)

    use

    2011-12-05

    Dec 5, 2011 ... successfully from giant panda using reverse transcription- polymerase chain reaction (RT-PCR) and touch-down PCR technology, ... The RPL37A gene could be readily expressed in Escherichia coli because it was fused with the .... molecules were transformed into E. coli competent cells (JM109), and then ...

  18. Giant Molluscum Contagiosum In Acute Lymphoblastic Leukaemia

    Directory of Open Access Journals (Sweden)

    Venkatesan Sivaraman

    2001-01-01

    Full Text Available A 14 year old female with acute lymphoblastic leukaemia had a tumoral lesion over the face of 3 months duration. Excision biopsy of the lesion confirmed it to be molluscum contagiosum. Giant molluscum contagiosum attaining polypoidal character as seen in our patient is an uncommon presentation and hence being reported for its rarity.

  19. Tuberculosis Detection by Giant African Pouched Rats

    Science.gov (United States)

    Poling, Alan; Weetjens, Bart; Cox, Christophe; Beyene, Negussie; Durgin, Amy; Mahoney, Amanda

    2011-01-01

    In recent years, operant discrimination training procedures have been used to teach giant African pouched rats to detect tuberculosis (TB) in human sputum samples. This article summarizes how the rats are trained and used operationally, as well as their performance in studies published to date. Available data suggest that pouched rats, which can…

  20. Reading on the Shoulders of Giants

    Science.gov (United States)

    Ben-Chaim, Michael; Riendeau, Michael

    2012-01-01

    Reflecting on his successful scientific career, Isaac Newton highlighted his intellectual debt to his predecessors. "If I have seen further," he wrote, "it was "only" by standing on the shoulders of giants." The authors have chosen the title of their article as a token of recognition of their debt to the teachings of…

  1. Antiproliferative heparin (glycosaminoglycans) isolated from giant ...

    African Journals Online (AJOL)

    Heparin was isolated from two bivalve mollusks, Tridacna maxima (giant clam) and Perna viridis (green mussel). The isolated heparin was quantified in crude as well as purified samples and they were estimated as 2.72 and 2.2 g/kg (in crude) and 260 and 248 mg/g (in purified samples) in T. maxima and P. viridis, ...

  2. Southern Africa - a giant natural photochemical reactor

    CSIR Research Space (South Africa)

    Diab, RD

    2006-04-01

    Full Text Available The analogy of a ‘giant natural photochemical reactor’ is extended in this paper to the central and southern African tropics, where tropospheric ozone enhancement occurs over a vast geographical area from the Congo to South Africa, and over a long...

  3. Polymyalgia rheumatica and giant cell arteritis.

    Science.gov (United States)

    Unwin, Brian; Williams, Cynthia M; Gilliland, William

    2006-11-01

    Polymyalgia rheumatica and giant cell arteritis are common, closely related vasculitic conditions that almost exclusively occur in patients older than 50 years. They may be manifestations of the same underlying disease and often coexist. Patients with polymyalgia rheumatica usually present with acute onset of stiffness and pain in the shoulder and pelvic musculature, which may be accompanied by fever, malaise, and weight loss. If untreated, polymyalgia rheumatica may result in significant disability. Giant cell arteritis may manifest as visual loss or diplopia, abnormalities of the temporal artery such as tenderness or decreased pulsation, jaw claudication, and new-onset headaches. Erythrocyte sedimentation rate and temporal artery biopsy help make the diagnosis. Giant cell arteritis requires urgent diagnosis because without treatment it may lead to irreversible blindness. Patients with either condition also may have nonspecific symptoms. Corticosteroids are the mainstay of therapy for both conditions, with higher doses required for treatment of giant cell arteritis. Duration of corticosteroid therapy can be five years or longer before complete clinical remission is achieved. Monitoring for corticosteroid-associated side effects such as osteoporosis and diabetes, as well as for relapses and flare-ups, is key to chronic management. The prognosis for either condition, if treated, is good.

  4. Giant mucinous cystadenoma: Case report | Nwobodo | Nigerian ...

    African Journals Online (AJOL)

    Nigerian Journal of Clinical Practice. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 13, No 2 (2010) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Giant mucinous cystadenoma: Case report.

  5. The giant paratesticular tumor in elderly

    Directory of Open Access Journals (Sweden)

    Parag S Bhirud

    2014-01-01

    Full Text Available Paratesticular tumor is an extremely rare. We present a case of paratesticular tumor in an elderly person of 84-year-old, which was presented as very large localized intrascrotal mass. This required subsequently orchidectomy. Histopathology confirmed the diagnosis as serous cystadenoma. Such a giant paratesticular mass, which was localized, has not been described previously.

  6. Massive Spontaneous Hemothorax, Giant Intrathoracic Meningocele ...

    African Journals Online (AJOL)

    Massive Spontaneous Hemothorax, Giant Intrathoracic. Meningocele, and Kyphoscoliosis in Neurofibromatosis Type 1. Ayodeji Salman Yusuf, Ashok Pillai1, Sajesh K. Menon1, Dilip Panikar1. INTRODUCTION. Neurofibromatosis type 1 (NF‑1) is an autosomal dominant disease with an incidence ranging from. 1 in 2500 to ...

  7. Polarization Spectra of Extrasolar Giant Planets

    NARCIS (Netherlands)

    Stam, D.M.

    2004-01-01

    We present simulated spectra of the flux and degree of polarization of starlight that is reflected by extrasolar giant planets (EGPs). In particular the polarization depends strongly on the structure of the planetary atmosphere, and appears to be a valuable tool for the characterization of EGPs.

  8. Giant cell arteritis: diagnosis and treatment.

    Science.gov (United States)

    Calvo Romero, J M

    2015-01-01

    Giant cell arteritis is the most common primary systemic vasculitis in adults. The condition is granulomatous arteritis of large and medium vessels, which occurs almost exclusively in patients aged 50 years or more. This article reviews the diagnosis and treatment of the disease. Copyright © 2015. Published by Elsevier España, S.L.U.

  9. Giant complex odontoma of the maxillary antrum

    African Journals Online (AJOL)

    1983-04-30

    Apr 30, 1983 ... Giant complex odontoma of the maxillary antrum. A case report. DIANNE B. MENDELSOHN, Y. HERTZANU, R. B. J. GLASS, G. KASSNER,. M. ALTINI. Summary ... completely filled the maxillary antrum, resulting in elevation of the orbit and .... out cortical bone, resulting in facial asymmetry. Radiographically ...

  10. Giant Presternal Dermoid Cyst: An Adult Case

    African Journals Online (AJOL)

    The ANNALS of AFRICAN SURGERY | www.sskenya.org/journal. The ANNALS of AFRICAN SURGERY. July 2014 Volume 11 Issue 2. 47. CASE REPORT. Giant Presternal Dermoid Cyst: An Adult. Case. Lakranbi M1, Tazi N1, Sekal M2, Amarti A2, M.Smahi M1. 1. Department Of Thoracic Surgery, University Hospital, Fes, ...

  11. Giant Cystic Retroperitoneal Lymphangioma in an Adult

    Directory of Open Access Journals (Sweden)

    Mary Mathew

    2013-06-01

    Full Text Available Lymphangiomas are uncommon benign neoplasms resulting from malformation of the lymphatic vessels. These lesions usually manifest in young individuals. Retroperitoneal lymphangiomas are very rare and may mimic various benign and malignant tumours. We report a rare case of giant retroperitoneal lymphangioma in a 51 year old male. [J Interdiscipl Histopathol 2013; 1(3.000: 172-174

  12. Arthroplasty for tenosynovial giant cell tumors

    NARCIS (Netherlands)

    Verspoor, F.G.; Hannink, G.; Scholte, A.; Geest, I.C. van der; Schreuder, H.W.

    2016-01-01

    Background and purpose - Tenosynovial giant cell tumors (t-GCTs) can behave aggressively locally and affect joint function and quality of life. The role of arthroplasty in the treatment of t-GCT is uncertain. We report the results of arthroplasty in t-GCT patients. Patients and methods - t-GCT

  13. [Giant paraovarian cyst in childhood - Case report].

    Science.gov (United States)

    Torres, Janina P; Íñiguez, Rodrigo D

    2015-01-01

    Paraovarian cysts are very uncommon in children To present a case of giant paraovarian cyst case in a child and its management using a modified laparoscopic-assisted technique A 13-year-old patient with a 15 day-history of intermittent abdominal pain, located in the left hemiabdomen and associated with progressive increase in abdominal volume. Diagnostic imaging was inconclusive, describing a giant cystic formation that filled up the abdomen, but without specifying its origin. Laboratory tests and tumor markers were within normal range. Video-assisted transumbilical cystectomy, a modified laparoscopic procedure with diagnostic and therapeutic intent, was performed with a successful outcome. The histological study reported giant paraovarian cyst. Cytology results were negative for tumor cells. The patient remained asymptomatic during the postoperative follow-up. The video-assisted transumbilical cystectomy is a safe procedure and an excellent diagnostic and therapeutic alternative for the treatment of giant paraovarian cysts. Copyright © 2015. Publicado por Elsevier España, S.L.U.

  14. Robust giant magnetoresistive effect type multilayer sensor

    NARCIS (Netherlands)

    Lenssen, K.M.H.; Kuiper, A.E.T.; Roozeboom, F.

    2002-01-01

    A robust Giant Magneto Resistive effect type multilayer sensor comprising a free and a pinned ferromagnetic layer, which can withstand high temperatures and strong magnetic fields as required in automotive applications. The GMR multi-layer has an asymmetric magneto-resistive curve and enables

  15. Giant pubertal prolactinoma: Complete resolution following short ...

    African Journals Online (AJOL)

    2016-04-06

    Apr 6, 2016 ... 23.9 kg/m2, axillary‑pubic hair growth was at tanner stage. 1, right and left testis volume of 8 mL, and penis size was. 6.5 cm. In laboratory examinations, hyperprolactinemia. (>200 ng/mL), hypogonadotropic hypogonadism,. Giant pubertal prolactinoma: Complete resolution following short term carbegoline ...

  16. Giant Retroperitoneal Lipoma in an Infant

    African Journals Online (AJOL)

    2010-06-29

    Jun 29, 2010 ... 33. Giant Retroperitoneal Lipoma in an Infant. A. M. Mohammad, A. A. Yakubu. INTRODUCTION. Lipomas are the most common soft tissue tumors that are encountered in clinical practice. Lipoma of the abdominal cavity, a benign neoplasm of mature fat cells usually presents as an asymptomatic abdominal.

  17. The Giant Radio Array for Neutrino Detection

    DEFF Research Database (Denmark)

    Martineau-Huynh, Olivier; Bustamante, Mauricio; Carvalho, Washington

    2017-01-01

    The Giant Radio Array for Neutrino Detection (GRAND) is a planned array of ~200 000 radio antennas deployed over ~200 000 km2 in a mountainous site. It aims primarly at detecting high-energy neutrinos via the observation of extensive air showers induced by the decay in the atmosphere of taus...

  18. The operation of giant incisional hernia

    DEFF Research Database (Denmark)

    Eriksson, Axelina; Krag, Christen; Jørgensen, Lars Nannestad

    2014-01-01

    Incisional hernia is a common complication to laparotomy impacting negatively on quality of life, risk of emergency surgery and cosmesis. The operation of giant incisional hernia (cross diameter of hernia defect > 20 cm) is a high risk procedure and the surgical techniques are not based on high...

  19. Floret-like multinucleated giant cells in neurofibroma

    Directory of Open Access Journals (Sweden)

    Golka Dariusz

    2007-12-01

    Full Text Available Abstract This short report discusses a case of neurofibroma containing floret-like multinucleated giant cells. This being the second such case in the literature. Floret-like multinucleated giant cells have been reported in gynaecomastia and neurofibroma in neurofibromatosis type 1. These cells have been reported in uncommon soft tissue tumours including pleomorphic lipoma, giant cell collagenoma, giant cell fibroblastoma and giant cell angiofibroma. We recommend these cells to be interpreted carefully keeping in mind the rare malignant change in neurofibromas. Immunohistochemistry would help in defining the nature of such cells.

  20. A Jupiter-mass planet around the K0 giant HD 208897

    Science.gov (United States)

    Yılmaz, M.; Sato, B.; Bikmaev, I.; Selam, S. O.; Izumiura, H.; Keskin, V.; Kambe, E.; Melnikov, S. S.; Galeev, A.; Özavcı, İ.; Irtuganov, E. N.; Zhuchkov, R. Ya.

    2017-11-01

    For over 10 years, we have carried out a precise radial velocity (RV) survey to find substellar companions around evolved G, K-type stars to extend our knowledge of planet formation and evolution. We performed high precision RV measurements for the giant star HD 208897 using an iodine (I2) absorption cell. The measurements were made at TÜBİTAK National Observatory (TUG; RTT150) and Okayama Astrophysical Observatory (OAO). For the origin of the periodic variation seen in the RV data of the star, we adopted a Keplerian motion caused by an unseen companion. We found that the star hosts a planet with a minimum mass of m2sini = 1.40 MJ, which is relatively low compared to those of known planets orbiting evolved intermediate-mass stars. The planet is in a nearly circular orbit with a period of P = 353 days at about 1 AU distance from the host star. The star is metal rich and located at the early phase of ascent along the red giant branch. The photometric observations of the star at Ankara University Kreiken Observatory (AUKR) and the Hipparcos photometry show no sign of variation with periods associated with the RV variation. Neither bisector velocity analysis nor analysis of the Ca II and Hα lines shows any correlation with the RV measurements. This work was supported by The Scientific and Technological Research Council of Turkey (TÜBİTAK), the project number of 114F099.

  1. CD34 expression in glioblastoma and giant cell glioblastoma.

    Science.gov (United States)

    Galloway, M

    2010-01-01

    This study aimed to determine whether CD34 is expressed in glioblastomas and giant cell glioblastomas, as this information may be of value when attempting to differentiate between giant cell glioblastomas and other relevant differential diagnoses such as pleomorphic xanthoastrocytomas with anaplastic features and anaplastic gangliogliomas. 11 giant cell glioblastomas and 16 non-giant cell glioblastomas were assessed with immunocytochemical staining for CD34. Standard immunocytochemical techniques were used, to reflect the staining patterns likely to be seen in routine diagnostic practice. Positive staining refers to staining of neoplastic cells. 73% of giant cell glioblastomas showed some degree of staining for CD34, and 55% showed strong widespread staining. 56% of non-giant cell glioblastomas showed some degree of CD34 staining, and 25% showed strong widespread staining. Both giant cell and non-giant cell glioblastomas frequently show CD34 expression by neoplastic cells, which may in some cases be strong and diffuse. Strong widespread staining of neoplastic cells for CD34 was more frequent in giant cell than non-giant cell glioblastomas, however this difference was not statistically significant. CD34 staining in isolation is unlikely to be of assistance in differentiating between giant cell glioblastoma and pleomorphic xanthoastrocytomas with anaplastic features or anaplastic gangliogliomas.

  2. Giant hepatic regenerative nodules in Alagille syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Rapp, Jordan B. [Lewis Katz School of Medicine at Temple University, Department of Radiology, Temple University Hospital, Philadelphia, PA (United States); Bellah, Richard D.; Anupindi, Sudha A. [The Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States); University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA (United States); Maya, Carolina [The Children' s Hospital of Philadelphia, Department of Radiology, Philadelphia, PA (United States); Pawel, Bruce R. [University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA (United States); The Children' s Hospital of Philadelphia, Department of Pathology and Laboratory Medicine, Philadelphia, PA (United States)

    2017-02-15

    Children with Alagille syndrome undergo surveillance radiologic examinations as they are at risk for developing cirrhosis and hepatocellular carcinoma. There is limited literature on the imaging of liver masses in Alagille syndrome. We report the ultrasound (US) and magnetic resonance imaging (MRI) appearances of incidental benign giant hepatic regenerative nodules in this population. To describe the imaging findings of giant regenerative nodules in patients with Alagille syndrome. A retrospective search of the hospital database was performed to find all cases of hepatic masses in patients with Alagille syndrome during a 10-year period. Imaging, clinical charts, laboratory data and available pathology were reviewed and analyzed and summarized for each patient. Twenty of 45 patients with confirmed Alagille syndrome had imaging studies. Of those, we identified six with giant focal liver masses. All six patients had large central hepatic masses that were remarkably similar on US and MRI, in addition to having features of cirrhosis. In each case, the mass was located in hepatic segment VIII and imaging showed the mass splaying the main portal venous branches at the hepatic hilum, as well as smaller portal and hepatic venous branches coursing through them. On MRI, signal intensity of the mass was isointense to liver on T1-weighted sequences in four of six patients, but hyperintense on T1 in two of six patients. In all six cases, the mass was hypointense on T2- weighted sequences. The mass post-contrast was isointense to adjacent liver in all phases in five the cases. Five out of six patients had pathological correlation demonstrating preserved ductal architecture confirming the final diagnosis of a regenerative nodule. Giant hepatic regenerative nodules with characteristic US and MR features can occur in patients with Alagille syndrome with underlying cirrhosis. Recognizing these lesions as benign giant hepatic regenerative nodules should, thereby, mitigate any need for

  3. Modeling Impacts of Climate Change on Giant Panda Habitat

    Directory of Open Access Journals (Sweden)

    Melissa Songer

    2012-01-01

    Full Text Available Giant pandas (Ailuropoda melanoleuca are one of the most widely recognized endangered species globally. Habitat loss and fragmentation are the main threats, and climate change could significantly impact giant panda survival. We integrated giant panda habitat information with general climate models (GCMs to predict future geographic distribution and fragmentation of giant panda habitat. Results support a major general prediction of climate change—a shift of habitats towards higher elevation and higher latitudes. Our models predict climate change could reduce giant panda habitat by nearly 60% over 70 years. New areas may become suitable outside the current geographic range but much of these areas is far from the current giant panda range and only 15% fall within the current protected area system. Long-term survival of giant pandas will require the creation of new protected areas that are likely to support suitable habitat even if the climate changes.

  4. Mars’ Growth Stunted by an Early Giant Planet Instability

    Science.gov (United States)

    Clement, Matthew; Kaib, Nathan A.; Raymond, Sean N.; Walsh, Kevin J.

    2017-10-01

    Many dynamical aspects of the solar system can be explained by the outer planets experiencing a period of orbital instability. Though often correlated with a perceived delayed spike in the lunar cratering record known as the Late Heavy Bombardment (LHB), recent work suggests that this event may have occurred during the epoch of terrestrial planet formation. Though current simulations of terrestrial accretion can reproduce many observed qualities of the solar system, replicating the small mass of Mars requires modification to standard planet formation models. Here we use direct numerical simulations to show that an early instability in the outer solar system regularly yields properly sized Mars analogues. In 80% of simulations, we produce a Mars of the appropriate mass. Our most successful outcomes occur when the terrestrial planets evolve 10 million years (Myr), and accrete several Mars sized embryos in the Mars forming region before the instability takes place. Mars is left behind as a stranded embryo, while the remainder of these bodies are either ejected from the system or scattered towards the inner solar system where they deliver water to Earth. An early giant planet instability can thus replicate both the inner and outer solar system in a single model.

  5. Differential population studies using asteroseismology: Solar-like oscillating giants in CoRoT fields LRc01 and LRa01

    Directory of Open Access Journals (Sweden)

    Casagrande L.

    2013-03-01

    Full Text Available Solar-like oscillating giants observed by the space-borne satellites CoRoT and Kepler can be used as key tracers of stellar populations in the Milky Way. When combined with additional photometric/spectroscopic constraints, the pulsation spectra of solar-like oscillating giant stars not only reveal their radii, and hence distances, but also provide well-constrained estimates of their masses, which can be used as proxies for the ages of these evolved stars. In this contribution we provide supplementary material to the comparison we presented in Miglio et al. (2013 between populations of giants observed by CoRoT in the fields designated LRc01 and LRa01.

  6. Cannibals in the thick disk: the young α-rich stars as evolved blue stragglers

    Science.gov (United States)

    Jofré, P.; Jorissen, A.; Van Eck, S.; Izzard, R. G.; Masseron, T.; Hawkins, K.; Gilmore, G.; Paladini, C.; Escorza, A.; Blanco-Cuaresma, S.; Manick, R.

    2016-10-01

    Spectro-seismic measurements of red giants enabled the recent discovery of stars in the thick disk that are more massive than 1.4 M⊙. While it has been claimed that most of these stars are younger than the rest of the typical thick disk stars, we show evidence that they might be products of mass transfer in binary evolution, notably evolved blue stragglers. We took new measurements of the radial velocities in a sample of 26 stars from APOKASC, including 13 "young" stars and 13 "old" stars with similar stellar parameters but with masses below 1.2 M⊙ and found that more of the young starsappear to be in binary systems with respect to the old stars.Furthermore, we show that the young stars do not follow the expected trend of [C/H] ratios versus mass for individual stars. However, with a population synthesis of low-mass stars including binary evolution and mass transfer, we can reproduce the observed [C/N] ratios versus mass. Our study shows how asteroseismology of solar-type red giants provides us with a unique opportunity to study the evolution of field blue stragglers after they have left the main-sequence.

  7. The evolved slowly pulsating B star 18 Peg: A testbed for upper main sequence stellar evolution

    Science.gov (United States)

    Irrgang, A.; De Cat, P.; Tkachenko, A.; Deshpande, A.; Moehler, S.; Mugrauer, M.; Janousch, D.

    2017-09-01

    The bright B3 III giant star 18 Peg turns out to be a slowly pulsating B star in a long period binary with a main-sequence star or a neutron star as companion. Given that it is one of the most evolved members of this class of massive pulsating stars, an accurate determination of the location of 18 Peg in the Hertzsprung-Russell (H-R) diagram would provide a lower limit on the width of the upper main sequence and hence would reveal information about the efficiency of the convective overshooting. We explain why long-term space-based observations are needed and how BRITE could play a crucial role in the gathering of the mandatory ingredients to test the models of the upper main sequence evolution.

  8. Ultrabass Sounds of the Giant Star xi Hya

    Science.gov (United States)

    2002-05-01

    times larger. The new observations demonstrate that xi Hya oscillates with several periods of around 3 hours. xi Hya is now approaching the end of its life - it is about to expand its outer envelope and to become a "red giant star" . It is quite different from stars like the Sun, which are only halfway through their active life. xi Hya is considerably more massive than any other star in which solar-like oscillations have so far been detected. This observational feat allows to study for the first time with seismic techniques the interior of such a highly evolved star. It paves the way for similar studies of different types of stars. A new chapter of stellar astrophysics is now opening as asteroseismology establishes itself as an ingenious method that is able to revolutionise our detailed understanding of stellar interiors and the overall evolution of stars . PR Photo 13a/02 : Oscillation frequencies in the Giant Star xi Hya PR Photo 13b/02 : Non-radial oscillations of xi Hya (computer graphics) PR Audio Clip 01/02 : Listen to the sound of xi Hya (RealMedia and MP3) The difficult art of asteroseismology Helioseismology (seismology of the Sun) is based on measurements of the changing radial velocity of the solar upper atmospheric layers (the "surface") by means of the well-known Doppler effect, as this surface moves up and down during acoustic oscillations. The corresponding amplitudes are very small, with velocities of up to 15 - 20 cm/sec, and the typical period is around 5 minutes. Therefore the phenomenon was first known as the "five-minute oscillations". Intensity measurements have also been tried, but the noise level is larger than for velocity data due to the presence of "granulation" (moving cells of hot gas) on the solar surface. In the case of larger and brighter stars like the giant stars, the corresponding amplitudes and periods increase. For instance, theoretical predictions for the giant star xi Hya have indicated that velocity amplitudes of about 7 m/sec and

  9. Evolving wormhole geometries within nonlinear electrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Arellano, Aaron V B [Facultad de Ciencias, Universidad Autonoma del Estado de Mexico, El Cerrillo, Piedras Blancas, CP 50200, Toluca (Mexico); Lobo, Francisco S N [Centro de Astronomia e Astrofisica da Universidade de Lisboa, Campo Grande, Ed C8 1749-016 Lisbon (Portugal)

    2006-10-21

    In this work, we explore the possibility of evolving (2 + 1) and (3 + 1)-dimensional wormhole spacetimes, conformally related to the respective static geometries, within the context of nonlinear electrodynamics. For (3 + 1)-dimensional spacetime, it is found that the Einstein field equation imposes a contracting wormhole solution and the obedience of the weak energy condition. Nevertheless, in the presence of an electric field, the latter presents a singularity at the throat; however, for a pure magnetic field the solution is regular. For (2 + 1)-dimensional case, it is also found that the physical fields are singular at the throat. Thus, taking into account the principle of finiteness, which states that a satisfactory theory should avoid physical quantities becoming infinite, one may rule out evolving (3 + 1)-dimensional wormhole solutions, in the presence of an electric field, and (2 + 1)-dimensional case coupled to nonlinear electrodynamics.

  10. Continual Learning through Evolvable Neural Turing Machines

    DEFF Research Database (Denmark)

    Lüders, Benno; Schläger, Mikkel; Risi, Sebastian

    2016-01-01

    Continual learning, i.e. the ability to sequentially learn tasks without catastrophic forgetting of previously learned ones, is an important open challenge in machine learning. In this paper we take a step in this direction by showing that the recently proposed Evolving Neural Turing Machine (ENT......) approach is able to perform one-shot learning in a reinforcement learning task without catastrophic forgetting of previously stored associations.......Continual learning, i.e. the ability to sequentially learn tasks without catastrophic forgetting of previously learned ones, is an important open challenge in machine learning. In this paper we take a step in this direction by showing that the recently proposed Evolving Neural Turing Machine (ENTM...

  11. Designing Garments to Evolve Over Time

    DEFF Research Database (Denmark)

    Riisberg, Vibeke; Grose, Lynda

    2017-01-01

    This paper proposes a REDO of the current fashion paradigm by investigating how garments might be designed to evolve over time. The purpose is to discuss ways of expanding the traditional role of the designer to include temporal dimensions of creating, producing and using clothes and to suggest a...... to a REDO of design education, to further research and the future fashion and textile industry.......This paper proposes a REDO of the current fashion paradigm by investigating how garments might be designed to evolve over time. The purpose is to discuss ways of expanding the traditional role of the designer to include temporal dimensions of creating, producing and using clothes and to suggest...... a range of potential fashion futures that decouple from declining resources. In the first part literature on 'Past and Present' historical and current aspects of sustainability in fashion and textiles are presented. In the second part, three exploratory case studies are described: Two projects by students...

  12. The Rise of a Giant

    Science.gov (United States)

    2006-12-01

    European astronomy has received a tremendous boost with the decision from ESO's governing body to proceed with detailed studies for the European Extremely Large Telescope. This study, with a budget of 57 million euro, will make it possible to start, in three years time, the construction of an optical/infrared telescope with a diameter around 40m that will revolutionise ground-based astronomy. The chosen design is based on a revolutionary concept specially developed for a telescope of this size. "The decision by the ESO Council to go ahead with the design study for an European Extremely Large Telescope is a very exciting one for European astronomy,", said Richard Wade, President of the ESO Council. "Today is a great day because the ESO Council has authorised us to go forward with the final design of the next flagship telescope of ESO,", says Catherine Cesarsky, ESO's Director General. ESO PR Photo 46/06 ESO PR Photo 46/06 The European Extremely Large Telescope (Artist's Impression) Since the end of last year, ESO has been working together with its user community of European astronomers and astrophysicists to define the new giant telescope needed by the middle of the next decade [1]. More than one hundred astronomers from all European countries have been involved throughout 2006, helping the ESO Project Offices to produce a novel concept, in which performance, cost, schedule and risk were carefully evaluated. This fast pace has also been possible thanks to early conceptual studies in Europe (such as the ESO OWL and the EURO-50 studies) and research and development done in collaboration with a large number of European institutes and high-tech industries to develop critical enabling technologies within the framework of the EU FP6 programme and with significant contributions from all partners. Provisionally dubbed E-ELT for the European Extremely Large Telescope, ESO's innovative concept was presented in detail two weeks ago to more than 250 European astronomers at a

  13. Antibody therapeutics - the evolving patent landscape.

    Science.gov (United States)

    Petering, Jenny; McManamny, Patrick; Honeyman, Jane

    2011-09-01

    The antibody patent landscape has evolved dramatically over the past 30 years, particularly in areas of technology relating to antibody modification to reduce immunogenicity in humans or improve antibody function. In some cases antibody techniques that were developed in the 1980s are still the subject of patent protection in the United States or Canada. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. The evolving epidemiology of inflammatory bowel disease.

    LENUS (Irish Health Repository)

    Shanahan, Fergus

    2009-07-01

    Epidemiologic studies in inflammatory bowel disease (IBD) include assessments of disease burden and evolving patterns of disease presentation. Although it is hoped that sound epidemiologic studies provide aetiological clues, traditional risk factor-based epidemiology has provided limited insights into either Crohn\\'s disease or ulcerative colitis etiopathogenesis. In this update, we will summarize how the changing epidemiology of IBD associated with modernization can be reconciled with current concepts of disease mechanisms and will discuss studies of clinically significant comorbidity in IBD.

  15. Directional Communication in Evolved Multiagent Teams

    Science.gov (United States)

    2013-06-10

    networks. Artificial Life, 15(2):185– 212, 2009. [23] K. O. Stanley and R. Miikkulainen. Evolving neural networks through augmenting topologies ...paper. 2.2 Neuroevolution of Augmenting Topologies The HyperNEAT approach is itself an extension of the original NEAT (Neu- roevolution of Augmenting ...Gauci and K. O. Stanley. Autonomous evolution of topographic regu- larities in artificial neural networks. Neural Computation, 22(7):1860–1898, 2010

  16. The Evolving Leadership Path of Visual Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Kluse, Michael; Peurrung, Anthony J.; Gracio, Deborah K.

    2012-01-02

    This is a requested book chapter for an internationally authored book on visual analytics and related fields, coordianted by a UK university and to be published by Springer in 2012. This chapter is an overview of the leadship strategies that PNNL's Jim Thomas and other stakeholders used to establish visual analytics as a field, and how those strategies may evolve in the future.

  17. Raeder paratrigeminal neuralgia evolving to hemicrania continua.

    Science.gov (United States)

    Porzukowiak, Tina Renae

    2015-04-01

    Raeder paratrigeminal neuralgia is most commonly characterized as deep, boring, nonpulsatile, severe, unilateral facial and head pain in the distribution of the V1 area combined with ipsilateral oculosympathetic palsy and autonomic symptoms. Raeder paratrigeminal neuralgia evolving into hemicrania continua, a rare primary, chronic headache syndrome characterized by unilateral pain and response to indomethacin, has rarely been documented. The purpose of this case report is to contribute to the medical literature a single case of Raeder paratrigeminal neuralgia presenting as multiple cranial nerve palsies that evolved into hemicrania continua that was successfully treated with onabotulinumtoxinA. A 52-year-old white woman presented to the emergency department with the complaint of severe, aching, constant eye pain radiating to the V1 area for 1 week with associated ptosis and photophobia of the left eye. Ocular examination revealed involvement of cranial nerves II, III, V, and VI. Additional symptoms included ipsilateral lacrimation, eyelid edema, and rhinorrhea. Extensive medical work-up showed normal results. Raeder paratrigeminal neuralgia was diagnosed with multiple cranial nerve involvement; the headache component became chronic with periodic exacerbations of autonomic symptoms evolving to a diagnosis of hemicrania continua. The patient was intolerant to traditional indomethacin treatment, and the headache was successfully treated with onabotulinumtoxinA injections. Recognition of ipsilateral signs such as miosis, ptosis, hydrosis, eyelid edema, hyperemia, rhinorrhea, or nasal congestion is useful in the differential diagnosis of painful ophthalmoplegia, particularly in the diagnosis of Raeder paratrigeminal neuralgia and hemicrania continua. This case study illustrates a rare presentation of Raeder paratrigeminal neuralgia evolving into hemicrania continua presenting as a painful ophthalmoplegia with multiple cranial nerve involvement. The example supports the

  18. Evolvability of Amyloidogenic Proteins in Human Brain

    Science.gov (United States)

    Hashimoto, Makoto; Ho, Gilbert; Sugama, Shuei; Takamatsu, Yoshiki; Shimizu, Yuka; Takenouchi, Takato; Waragai, Masaaki; Masliah, Eliezer

    2018-01-01

     Currently, the physiological roles of amyloidogenic proteins (APs) in human brain, such as amyloid-β and α-synuclein, are elusive. Given that many APs arose by gene duplication and have been resistant against the pressures of natural selection, APs may be associated with some functions that are advantageous for survival of offspring. Nonetheless, evolvability is the sole physiological quality of APs that has been characterized in microorganisms such as yeast. Since yeast and human brain may share similar strategies in coping with diverse range of critical environmental stresses, the objective of this paper was to discuss the potential role of evolvability of APs in aging-associated neurodegenerative disorders, including Alzheimer’s disease and Parkinson’s disease. Given the heterogeneity of APs in terms of structure and cytotoxicity, it is argued that APs might be involved in preconditioning against diverse stresses in human brain. It is further speculated that these stress-related APs, most likely protofibrillar forms, might be transmitted to offspring via the germline, conferring preconditioning against forthcoming stresses. Thus, APs might represent a vehicle for the inheritance of the acquired characteristics against environmental stresses. Curiously, such a characteristic of APs is reminiscent of Charles Darwin’s ‘gemmules’, imagined molecules of heritability described in his pangenesis theory. We propose that evolvability might be a physiological function of APs during the reproductive stage and neurodegenerative diseases could be a by-product effect manifested later in aging. Collectively, our evolvability hypothesis may play a complementary role in the pathophysiology of APs with the conventional amyloid cascade hypothesis. PMID:29439348

  19. High-order evolving surface finite element method for parabolic problems on evolving surfaces

    OpenAIRE

    Kovács, Balázs

    2016-01-01

    High-order spatial discretisations and full discretisations of parabolic partial differential equations on evolving surfaces are studied. We prove convergence of the high-order evolving surface finite element method, by showing high-order versions of geometric approximation errors and perturbation error estimates and by the careful error analysis of a modified Ritz map. Furthermore, convergence of full discretisations using backward difference formulae and implicit Runge-Kutta methods are als...

  20. On the asymptotic acoustic-mode phase in red giant stars and its dependence on evolutionary state

    DEFF Research Database (Denmark)

    Christensen-Dalsgaard, Jørgen; Silva Aguirre, Victor; Elsworth, Yvonne

    2014-01-01

    their determination of the asymptotic phase of radial oscillations in evolved stars and the evolutionary state, separating ascending-branch red giants from helium-burning stars in the ‘red clump’. Here, we provide a detailed analysis of this relation, which is found to derive from differences between these two...... classes of stars in the thermodynamic state of the convective envelope. There is potential for distinguishing red giants and clump stars based on the phase determined from observations that are too short to allow distinction based on determination of the period spacing for mixed modes. The analysis...... of the phase may also point to a better understanding of the potential for using the helium-ionization-induced acoustic glitch to determine the helium abundance in the envelopes of these stars....

  1. Cranial vault metastasis of giant cell tumor.

    Science.gov (United States)

    Notarianni, Christina; Abreo, Fluerette; Nanda, Anil

    2008-08-01

    Giant cell tumors are benign bony tumors involving the epiphysis of long bones. Here, we present a case of giant cell tumor involving the parietal bone that had metastasized from the sacrum. A 36-year-old healthy woman presented to neurosurgery clinic in April 2005 reporting a "bump" over the left parietal area that had been increasing in size over the past 6 months. The lesion was nontender, and the patient had no other associated neurological symptoms. As we have presented here, cranial vault metastases can occur and should be considered in a differential diagnosis of bony lesions found in this location. These distant metastases, although relatively uncommon, must be managed aggressively. Newer radiation treatments seem to be a promising favorable adjunct to wide local resection and should be investigated further for these tumors.

  2. Viral metagenomics: are we missing the giants?

    Science.gov (United States)

    Halary, S; Temmam, S; Raoult, D; Desnues, C

    2016-06-01

    Amoeba-infecting giant viruses are recently discovered viruses that have been isolated from diverse environments all around the world. In parallel to isolation efforts, metagenomics confirmed their worldwide distribution from a broad range of environmental and host-associated samples, including humans, depicting them as a major component of eukaryotic viruses in nature and a possible resident of the human/animal virome whose role is still unclear. Nevertheless, metagenomics data about amoeba-infecting giant viruses still remain scarce, mainly because of methodological limitations. Efforts should be pursued both at the metagenomic sample preparation level and on in silico analyses to better understand their roles in the environment and in human/animal health and disease. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Multicentric giant cell tumor around the knee

    Directory of Open Access Journals (Sweden)

    Salgia Anil

    2007-01-01

    Full Text Available A case of multicentric giant cell tumor with synchronous occurrence in all three bones around the knee is reported here in view of its rarity. A 33-year-old average built male reported with complaints of severe pain, gradually increasing swelling around the right knee. A 3 x 2 cm swelling was present on the lateral aspect of the distal end of the right femur and a 3 x 3 cm swelling on the proximal part of the right tibia. Plain X-ray of right knee showed subarticular eccentrically located expansile lytic lesion in the lateral tibia condyle, lateral condyle of femur and patella. Fine needle aspiration cytology and subsequent histology ascertained the diagnosis of giant cell tumor of the bone. The patient was treated successfully with curettage, bone grafting and methyl methacrylate cementing (Sandwich technique.

  4. [Giant scrotal lymphedema caused by Milroy's disease].

    Science.gov (United States)

    Gueglio, G; Quijada, Edin; Salas, H; Daels, P; Tejerizo, J; Chernobilsky, V; Giúdice, C; Damia, O

    2003-10-01

    To report a new case of giant scrotal lymphedema due to Milroy's disease, its treatment and outcome. A 27-year-old man with generalized congenital lymphedema presented with a giant scrotal mass which interfered with his daily activities and physiological necessities. Physical examination showed a scrotal mass 40 x 40 cm in size and a normal penis. CT scan showed a homogeneous mass, thickened vaginal tunica, and bilateral hydrocele. A surgical procedure was performed including mass resection (5.6 kg), and bilateral hydrocelectomy. Skin defect was covered with skin grafts. Several therapeutic alternatives have been suggested for Milroy's disease with genital involvement. Nevertheless, when complications are as severe as in the present case, the only valid therapy is surgery.

  5. Giant peripheral osteoma of the mandible

    Directory of Open Access Journals (Sweden)

    Sushil Kachewar

    2012-01-01

    Full Text Available Osseous expansion of any body part is an unwelcome guest and deep are its impacts when it is located on the face. The bigger the lesion, the more bitter is the psycho-social trauma to the affected individual. This article describes the case of a 50 year old female who presented with painless swelling of the right submandibular region manifesting as a dreadful cosmetic disfigurement. The mass had been progressing slowly for the last 15 years. Imaging showed a giant peripheral osteoma of 10.8 cm involving buccal and lingual surface of the body, ramus, angle and inferior border of the right side of mandible. To the best of our knowledge, a giant peripheral osteoma of mandible having size more than 10 cm has never been reported earlier.

  6. Thermal escape from extrasolar giant planets.

    Science.gov (United States)

    Koskinen, Tommi T; Lavvas, Panayotis; Harris, Matthew J; Yelle, Roger V

    2014-04-28

    The detection of hot atomic hydrogen and heavy atoms and ions at high altitudes around close-in extrasolar giant planets (EGPs) such as HD209458b implies that these planets have hot and rapidly escaping atmospheres that extend to several planetary radii. These characteristics, however, cannot be generalized to all close-in EGPs. The thermal escape mechanism and mass loss rate from EGPs depend on a complex interplay between photochemistry and radiative transfer driven by the stellar UV radiation. In this study, we explore how these processes change under different levels of irradiation on giant planets with different characteristics. We confirm that there are two distinct regimes of thermal escape from EGPs, and that the transition between these regimes is relatively sharp. Our results have implications for thermal mass loss rates from different EGPs that we discuss in the context of currently known planets and the detectability of their upper atmospheres.

  7. Organ Sparing Surgery for a Giant Liposarcoma

    Directory of Open Access Journals (Sweden)

    Huseyin Ozgur Aytac

    2015-03-01

    Full Text Available Liposarcomas those are malignant soft tissue tumors often occur in large sizes in the retroperitoneum and abdomen due to their silent clinic. Excision with negative margins is the gold standard of treatment. A case operated on for a giant intraabdominal liposarcoma is being reported. A giant soft tissue tumor filling the whole abdomen was determined in the computed tomography scan. Core biopsy was obtained and demonstrated a well-differentiated liposarcoma. A 15 kg of mass 44x30x14 cm in size was excised en-bloc. Pathological examination of this tumor showed a well-differentiated liposarcoma with mixoid parts. No recurrence was observed in two years of follow-up despite any adjuvant therapy. This is to be one of the largest retroperitoneal sarcomas in the literature. [Cukurova Med J 2015; 40(Suppl 1: 136-141

  8. Atypical presentations of retroperitoneal giant schwannomas

    Directory of Open Access Journals (Sweden)

    Cetin Dincel

    2011-04-01

    Full Text Available Schwannomas are usually benign rare tumors that originating from Schwann cells of peripheral nerve sheaths. Presentation is generally varied and changed in a non-specific range from abdominal mass, flank pain to incidental findings. Herein we report 2 cases of retroperitoneal giant schwannomas with different clinical presentations, of whom one presented with vague abdominal pain, palpable abdominal mass for 4 years, swelling and bilateral hydronephrosis that caused by giant abdominal mass; the other one presented with right flank pain, rectal hemorrhage and lower extremities edema. Two patients were treated by complete surgical excision of masses. The histological and immunohistochemical diagnosis was reported as benign schwannoma. Both of patients are doing well and had no recurrence in 9 years and 28 months follow-up, respectively.

  9. Peripheral giant cell granuloma: a case report

    OpenAIRE

    Kota, Kasim; Kodanda, Ram; Jaisekharan, V P

    2015-01-01

    Peripheral giant cell granuloma (PGCG) is a non neoplastic reactive lesion of the gingiva, originating from the periosteum or periodontal membrane following local irritation or chronic trauma. PGCG manifests as a red-purple growth located in the gingiva or edentulous alveolar margins. The lesion can develop at any age, shows a slight female predilection. Usually, they cause one or the other problem in eruption or alignment of teeth, but may also present without disturbing the normal occlusion...

  10. Population genetic structure of Aldabra giant tortoises

    OpenAIRE

    Balmer, Oliver; Ciofi, Claudio; Galbraith, David A.; Swingland, Ian R.; Zug, George R.,; Caccone, Adalgisa

    2011-01-01

    Evolution of population structure on islands is the result of physical processes linked to volcanism, orogenic events, changes in sea level, as well as habitat variation. We assessed patterns of genetic structure in the giant tortoise of the Aldabra atoll, where previous ecological studies suggested population subdivisions as a result of landscape discontinuity due to unsuitable habitat and island separation. Analysis of mitochondrial DNA (mtDNA) control region sequences and allelic variation...

  11. On the shape of giant soap bubbles

    NARCIS (Netherlands)

    Cohen, C.; Darbois Texier, B.; Reyssat, E.; Snoeijer, Jacobus Hendrikus; Quere, D.; Clanet, Christophe

    2017-01-01

    We study the effect of gravity on giant soap bubbles and show that it becomes dominant above the critical size ℓ=a2/e0ℓ=a2/e0, where e0e0 is the mean thickness of the soap film and a=γb/ρg−√a=γb/ρg is the capillary length ( γbγb stands for vapor–liquid surface tension, and ρρ stands for the liquid

  12. Giant osteoblastoma of temporal bone: case report

    Directory of Open Access Journals (Sweden)

    FIGUEIREDO EBERVAL GADELHA

    1998-01-01

    Full Text Available Benign osteoblastoma is an uncommon bone tumor accounting for approximately 1% of all bone tumors. There are only 35 cases of skull osteoblastoma reported in the literature. We describe the case of a 23 year old male with a giant osteoblastoma of temporal bone submitted to a total removal of the tumor after an effective embolization of all external carotid branches. The authors discuss diagnostic and management aspects of this uncommon skull tumor.

  13. Giant Leiomyosarcoma of the Urinary Bladder.

    Science.gov (United States)

    Ribeiro, José G A; Klojda, Carlos A B; Araújo, Claudio P De; Pires, Lucas A S; Babinski, Marcio A

    2016-05-01

    The bladder leiomyosarcoma is a rare and agressive mesenchymal tumour, and adult women of reproductive age have a higher incidence of developing the bladder leiomyosarcoma. The pathophysiology of the disease is not certain, and its main symptoms are hematuria, dysuria and abdominal pain. There are not a considerable amount of cases described in the literature. We report a case of a giant leiomyosarcoma of the urinary bladder in a 31-year-old woman.

  14. Extraction of the coefficient of giant magnetoresistance

    Energy Technology Data Exchange (ETDEWEB)

    Idzerda, Y.U. (Naval Research Laboratory, Washington, DC 20375 (United States)); Chen, C. (AT T Bell Laboratories, 600 Mountain Avenue, Murray Hill, New Jersey 07974 (United States)); Cheng, S. (Naval Surface Warfare Center, Silver Spring, Maryland 20910 (United States)); Vavra, W.; Prinz, G.A. (Naval Research Laboratory, Washington, DC 20375 (United States)); Meigs, G.; Lin, H. (AT T Bell Laboratories, 600 Mountain Avenue, Murray Hill, New Jersey 07974 (United States)); Ho, G.H. (Department of Physics, University of Pennsylvania, Philadelphia, Pennsylvania 19104 (United States))

    1994-06-20

    Element specific magnetic hysteresis (ESMH) loops have been used in conjunction with measured magnetoresistance curves to extract the coefficient of giant magnetoresistance (GMR), which is the maximum achievable value of the GMR independent of magnetic domain effects and incomplete moment alignment effects, for sputtered Fe/Cu/Co sandwiches on silicon substrates. Using the ESMH loops to calculate GMR curves, comparison with the measured GMR curves shows that the magnetization reversal process is best described by multidomain Ising behavior.

  15. Giant tonsillolith ? a rare cause of dysphagia

    OpenAIRE

    Dykes, M.; Izzat, S; Pothula, V

    2012-01-01

    Tonsilloliths are calcified concretions that originate within the palatal tonsil crypts. Moreover, development of these concretions into giant tonsilloliths is exceptionally uncommon. We present a 17-year-old female with a two-year history of increasing dysphagia, persistent oral cavity swelling and speech alteration. Clinical examination of the oral cavity revealed a large solid left tonsil with no obvious neck masses. Computer tomography demonstrated a well-defined, large calcified left ton...

  16. Giant basal cell carcinoma Carcinoma basocelular gigante

    Directory of Open Access Journals (Sweden)

    Nilton Nasser

    2012-06-01

    Full Text Available The basal cell carcinoma is the most common skin cancer but the giant vegetating basal cell carcinoma reaches less than 0.5 % of all basal cell carcinoma types. The Giant BCC, defined as a lesion with more than 5 cm at its largest diameter, is a rare form of BCC and commonly occurs on the trunk. This patient, male, 42 years old presents a Giant Basal Cell Carcinoma which reaches 180 cm2 on the right shoulder and was negligent in looking for treatment. Surgical treatment was performed and no signs of dissemination or local recurrence have been detected after follow up of five years.O carcinoma basocelular é o tipo mais comum de câncer de pele, mas o carcinoma basocelular gigante vegetante não atinge 0,5% de todos os tipos de carcinomas basocelulares. O Carcinoma Basocelular Gigante, definido como lesão maior que 5 cm no maior diâmetro, é uma forma rara de carcinoma basocelular e comumente ocorre no tronco. Este paciente apresenta um Carcinoma Basocelular Gigante com 180cm² no ombro direito e foi negligente em procurar tratamento. Foi realizado tratamento cirúrgico e nenhum sinal de disseminação ou recorrência local foi detectada após 5 anos.

  17. Giant Orbital Melanoma in a Heroin Abuser

    Directory of Open Access Journals (Sweden)

    Alena Furdova

    2017-04-01

    Full Text Available Purpose: The aim of this report was to report a heroin abuser with nondiagnosed giant uveal melanoma infiltrating the orbit and prolapsing through the face. Methods: We conducted a case report of the patient with giant melanoma. Results: In March 2013, a 39-year-old male with bleeding from the right side of his face was taken to the Emergency Center of the University Hospital Bratislava by ambulance. The heroin abusing, homeless male who had never been treated before reported a 2-year history of a prolapsed, dark colored mass from his eye. Acute computed tomography confirmed a solid mass 20 × 20 cm prolapsing from the orbit. The patient rejected primary care, accepted only 1 transfusion and left the hospital. Two months later, he was admitted to the hospital due to anemia after many collapses. Liver metastasis was present. Surgical palliative therapy was not possible due to his general status. The patient started fractionated external radiotherapy with 8.0 Gy Co60. Histopathological examination of the biopsy specimen showed malignant melanoma of the epitheloid type G2–3. The patient died in December 2013. Conclusion: Extraorbital formation of a melanoma mass may progress to a giant volume, and without treatment, led to metastases in the liver and to death after 9 months in our patient with anemia.

  18. Lipidized giant-cell glioblastoma of cerebellum.

    Science.gov (United States)

    Queiroz, L S; Faria, A V; Zanardi, V A; Netto, J R Menezes

    2005-01-01

    Glioblastoma multiforme is recognized rarely in the cerebellum. We describe a peculiar case with lipid accumulation in giant tumor cells, possibly the second example so far reported in this unusual location. A 46-year-old man with a 5-month history of headache, vomiting, dizziness and instability of gait, was found to have on magnetic resonance imaging an expanding mass situated deep in the left cerebellar hemisphere. The lesion was hypointense in T 1- and hyperintense in T2-weighted images, had poorly defined borders, peripheral edema and annular foci of contrast enhancement. Eight months after subtotal removal and radiotherapy, control MRI showed tumor recurrence with aggressive features. The patient was alive 15 months after operation but follow-up was eventually lost. Histologically, the tumor showed marked pleomorphism, with many giant cells characterized by finely vacuolated cytoplasm strongly suggestive of lipid accumulation. There were few, sometimes atypical mitotic figures and foci of endothelial proliferation. The tumor cells were strongly positive for GFAP, vimentin and S100 protein, all of which stressed the foamy appearance of the giant cells. About 15% of nuclei were positive for Ki-67. We considered the case to be a so-called lipidized glioblastoma, first recognized as a subtype by Kepes and Rubinstein [1981]. Differential diagnosis with anaplastic pleomorphic xanthoastrocytoma is discussed.

  19. A Vision for Ice Giant Exploration

    Science.gov (United States)

    Hofstadter, M.; Simon, A.; Atreya, S.; Banfield, D.; Fortney, J.; Hayes, A.; Hedman, M.; Hospodarsky, G.; Mandt, K.; Masters, A.; hide

    2017-01-01

    From Voyager to a Vision for 2050: NASA and ESA have just completed a study of candidate missionsto Uranus and Neptune, the so-called ice giant planets. It is a Pre-Decadal Survey Study, meant to inform the next Planetary Science Decadal Survey about opportunities for missions launching in the 2020's and early 2030's. There have been no space flight missions to the ice giants since the Voyager 2 flybys of Uranus in 1986 and Neptune in 1989. This paper presents some conclusions of that study (hereafter referred to as The Study), and how the results feed into a vision for where planetary science can be in 2050. Reaching that vision will require investments in technology andground-based science in the 2020's, flight during the 2030's along with continued technological development of both ground- and space-based capabilities, and data analysis and additional flights in the 2040's. We first discuss why exploring the ice giants is important. We then summarize the science objectives identified by The Study, and our vision of the science goals for 2050. We then review some of the technologies needed to make this vision a reality.

  20. Pulsating Aurora in Eveningside Giant Auroral Undulations

    Science.gov (United States)

    Ahrns, M. J.; Hampton, D. L.

    2016-12-01

    Giant auroral undulation events are characterized by large, periodic wavelike auroral structures occurring in at the boundary of the diffuse electron aurora and the subauroral zone. Previous papers regarding giant undulations (e.g. Lui et. al. 1982) were limited to satellite overpasses which provided only a snapshot of the event. We present high temporal and spatial resolution allsky camera imagery of several events. This imagery reveals pulsating aurora to be associated with giant undulations. This pulsating aurora is unusual in that it is in the evening sector, occurring within a very well-defined area, and is not closely associated with substorm activity. The data also yields undulation amplitude, phase speed, and wavelength, which is presented along with radar measurements of the ionospheric plasma drift for several events. Preliminary results suggest the undulations appear at areas of strong shear flow near the auroral/subauroral boundary, and give a dispersion relationship by comparing the wavelength and phase speed for various events. Lui, A. T. Y., C. I. Meng, and S. Ismail (1982), Large amplitude undulations on the equatorward boundary of the diffuse aurora, J. Geophys. Res., 87, 2385-2400.

  1. Giant Cell Tumor of Bone - an Overview

    Directory of Open Access Journals (Sweden)

    Anshul Sobti

    2016-01-01

    Full Text Available Giant Cell tumors (GCT are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be associated with a substantial disturbance of the local bony architecture that can be particularly troublesome in peri-articular locations. Its histogenesis remains unclear. It is characterized by a proliferation of mononuclear stromal cells and the presence of many multi- nucleated giant cells with homogenous distribution. There is no widely held consensus regarding the ideal treatment method selection. There are advocates of varying surgical techniques ranging from intra-lesional curettage to wide resection. As most giant cell tumors are benign and are located near a joint in young adults, several authors favor an intralesional approach that preserves anatomy of bone in lieu of resection. Although GCT is classified as a benign lesion, few patients develop progressive lung metastases with poor outcomes. Treatment is mainly surgical. Options of chemotherapy and radiotherapy are reserved for selected cases. Recent advances in the understanding of pathogenesis are essential to develop new treatments for this locally destructive primary bone tumor.

  2. Rare cause of odynophagia: Giant esophageal ulcer.

    Science.gov (United States)

    Veroux, Massimiliano; Aprile, Giuseppe; Amore, Francesca F; Corona, Daniela; Giaquinta, Alessia; Veroux, Pierfrancesco

    2016-04-14

    Gastrointestinal complications are a frequent cause of morbidity after transplantation and may affect up to 40% of kidney transplant recipients. Here we report a rare case of idiopathic giant esophageal ulcer in a kidney transplant recipient. A 37-year-old female presented with a one-week history of odynophagia and weight loss. Upon admission, the patient presented cold sores, and a quantitative cytomegalovirus polymerase chain reaction was positive (10(5) copies/mL). An upper endoscopy demonstrated the presence of a giant ulcer. Serological test and tissue biopsies were unable to demonstrate an infectious origin of the ulcer. Immunosuppression was reduced and everolimus was introduced. An empirical i.v. therapy with acyclovir was started, resulting in a dramatic improvement in symptoms and complete healing of the ulcer. Only two cases of idiopathic giant esophageal ulcer in kidney transplant recipients have been reported in the literature; in both cases, steroid therapy was successful without recurrence of symptoms or endoscopic findings. However, this report suggests that correction of immune imbalance is mandatory to treat such a rare complication.

  3. Evolvability Is an Evolved Ability: The Coding Concept as the Arch-Unit of Natural Selection.

    Science.gov (United States)

    Janković, Srdja; Ćirković, Milan M

    2016-03-01

    Physical processes that characterize living matter are qualitatively distinct in that they involve encoding and transfer of specific types of information. Such information plays an active part in the control of events that are ultimately linked to the capacity of the system to persist and multiply. This algorithmicity of life is a key prerequisite for its Darwinian evolution, driven by natural selection acting upon stochastically arising variations of the encoded information. The concept of evolvability attempts to define the total capacity of a system to evolve new encoded traits under appropriate conditions, i.e., the accessible section of total morphological space. Since this is dependent on previously evolved regulatory networks that govern information flow in the system, evolvability itself may be regarded as an evolved ability. The way information is physically written, read and modified in living cells (the "coding concept") has not changed substantially during the whole history of the Earth's biosphere. This biosphere, be it alone or one of many, is, accordingly, itself a product of natural selection, since the overall evolvability conferred by its coding concept (nucleic acids as information carriers with the "rulebook of meanings" provided by codons, as well as all the subsystems that regulate various conditional information-reading modes) certainly played a key role in enabling this biosphere to survive up to the present, through alterations of planetary conditions, including at least five catastrophic events linked to major mass extinctions. We submit that, whatever the actual prebiotic physical and chemical processes may have been on our home planet, or may, in principle, occur at some time and place in the Universe, a particular coding concept, with its respective potential to give rise to a biosphere, or class of biospheres, of a certain evolvability, may itself be regarded as a unit (indeed the arch-unit) of natural selection.

  4. Thermohaline mixing in evolved low-mass stars

    OpenAIRE

    Cantiello, M.; Langer, N.

    2010-01-01

    Thermohaline mixing has recently been proposed to occur in low-mass red giants, with large consequence for the chemical yields of low-mass stars. We investigate the role of thermohaline mixing during the evolution of stars between 1Msun and 3Msun, in comparison to other mixing processes acting in these stars. We use a stellar evolution code which includes rotational mixing, internal magnetic fields and thermohaline mixing. We confirm that during the red giant stage, thermohaline mixing has th...

  5. YKL-40 in giant cells and macrophages from patients with giant cell arteritis

    DEFF Research Database (Denmark)

    Johansen, J S; Baslund, B; Garbarsch, C

    1999-01-01

    OBJECTIVE: YKL-40, a mammalian member of the family 18 glycosyl hydrolases, is secreted by activated macrophages at a late stage of differentiation. Macrophages are present in inflammation of the arterial wall and are thought to participate in the pathogenesis of giant cell arteritis (GCA). The aim...... of this study was to evaluate whether macrophages and giant cells of patients with GCA produce YKL-40, and whether serum YKL-40 concentrations are elevated in these patients. METHODS: Serum YKL-40 was determined by radioimmunoassay in 19 patients with GCA and 8 patients with polymyalgia rheumatica (PMR) who...... was found in CD68+ giant cells and mononuclear cells located in the media. Macrophages located in the adventitia and intima were negative for YKL-40. At the time of diagnosis, patients with GCA had an increased median serum level of YKL-40 (256 microg/liter; P

  6. Survivability is more fundamental than evolvability.

    Directory of Open Access Journals (Sweden)

    Michael E Palmer

    Full Text Available For a lineage to survive over long time periods, it must sometimes change. This has given rise to the term evolvability, meaning the tendency to produce adaptive variation. One lineage may be superior to another in terms of its current standing variation, or it may tend to produce more adaptive variation. However, evolutionary outcomes depend on more than standing variation and produced adaptive variation: deleterious variation also matters. Evolvability, as most commonly interpreted, is not predictive of evolutionary outcomes. Here, we define a predictive measure of the evolutionary success of a lineage that we call the k-survivability, defined as the probability that the lineage avoids extinction for k generations. We estimate the k-survivability using multiple experimental replicates. Because we measure evolutionary outcomes, the initial standing variation, the full spectrum of generated variation, and the heritability of that variation are all incorporated. Survivability also accounts for the decreased joint likelihood of extinction of sub-lineages when they 1 disperse in space, or 2 diversify in lifestyle. We illustrate measurement of survivability with in silico models, and suggest that it may also be measured in vivo using multiple longitudinal replicates. The k-survivability is a metric that enables the quantitative study of, for example, the evolution of 1 mutation rates, 2 dispersal mechanisms, 3 the genotype-phenotype map, and 4 sexual reproduction, in temporally and spatially fluctuating environments. Although these disparate phenomena evolve by well-understood microevolutionary rules, they are also subject to the macroevolutionary constraint of long-term survivability.

  7. Present weather and climate: evolving conditions

    Science.gov (United States)

    Hoerling, Martin P; Dettinger, Michael; Wolter, Klaus; Lukas, Jeff; Eischeid, Jon K.; Nemani, Rama; Liebmann, Brant; Kunkel, Kenneth E.

    2013-01-01

    This chapter assesses weather and climate variability and trends in the Southwest, using observed climate and paleoclimate records. It analyzes the last 100 years of climate variability in comparison to the last 1,000 years, and links the important features of evolving climate conditions to river flow variability in four of the region’s major drainage basins. The chapter closes with an assessment of the monitoring and scientific research needed to increase confidence in understanding when climate episodes, events, and phenomena are attributable to human-caused climate change.

  8. f( R) gravity solutions for evolving wormholes

    Science.gov (United States)

    Bhattacharya, Subhra; Chakraborty, Subenoy

    2017-08-01

    The scalar-tensor f( R) theory of gravity is considered in the framework of a simple inhomogeneous space-time model. In this research we use the reconstruction technique to look for possible evolving wormhole solutions within viable f( R) gravity formalism. These f( R) models are then constrained so that they are consistent with existing experimental data. Energy conditions related to the matter threading the wormhole are analyzed graphically and are in general found to obey the null energy conditions (NEC) in regions around the throat, while in the limit f(R)=R, NEC can be violated at large in regions around the throat.

  9. Information theory, evolutionary innovations and evolvability.

    Science.gov (United States)

    Wagner, Andreas

    2017-12-05

    How difficult is it to 'discover' an evolutionary adaptation or innovation? I here suggest that information theory, in combination with high-throughput DNA sequencing, can help answer this question by quantifying a new phenotype's information content. I apply this framework to compute the phenotypic information associated with novel gene regulation and with the ability to use novel carbon sources. The framework can also help quantify how DNA duplications affect evolvability, estimate the complexity of phenotypes and clarify the meaning of 'progress' in Darwinian evolution.This article is part of the themed issue 'Process and pattern in innovations from cells to societies'. © 2017 The Author(s).

  10. Evolving Random Forest for Preference Learning

    DEFF Research Database (Denmark)

    Abou-Zleikha, Mohamed; Shaker, Noor

    2015-01-01

    This paper introduces a novel approach for pairwise preference learning through a combination of an evolutionary method and random forest. Grammatical evolution is used to describe the structure of the trees in the Random Forest (RF) and to handle the process of evolution. Evolved random forests ...... obtained for predicting pairwise self-reports of users for the three emotional states engagement, frustration and challenge show very promising results that are comparable and in some cases superior to those obtained from state-of-the-art methods....

  11. Three cases giant panda attack on human at Beijing Zoo.

    Science.gov (United States)

    Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo

    2014-01-01

    Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda's potentially dangerous behavior.

  12. Three cases giant panda attack on human at Beijing Zoo

    OpenAIRE

    Zhang, Peixun; Wang, Tianbing; Xiong, Jian; Xue, Feng; Xu, Hailin; Chen, Jianhai; Zhang, Dianying; Fu, Zhongguo; Jiang, Baoguo

    2014-01-01

    Panda is regarded as Chinese national treasure. Most people always thought they were cute and just ate bamboo and had never imagined a panda could be vicious. Giant panda attacks on human are rare. There, we present three cases of giant panda attacks on humans at the Panda House at Beijing Zoo from September 2006 to June 2009 to warn people of the giant panda’s potentially dangerous behavior.

  13. Giant arachnoid granulation in a patient with benign intracranial hypertension

    Energy Technology Data Exchange (ETDEWEB)

    Kiroglu, Yilmaz; Yaqci, Baki; Cirak, Bayram; Karabulut, Nevzat [Pamukkale University, Department of Radiology, School of Medicine, Denizli (Turkey)

    2008-10-15

    We report magnetic resonance (MR), computed tomography (CT) and angiographic imaging of an unusual giant arachnoid granulation in the superior sagittal sinus in a man with headache and vertigo. Intrasinus pressure measurements revealed a significant pressure gradient across the lesion. MR imaging is useful to identify giant arachnoid granulation and dural sinus thrombosis, whereas dural sinus pressure measurement in certain cases of giant arachnoid granulations can be used to evaluate the lesion as the cause of the patient's symptoms. (orig.)

  14. Transcatheter Arterial Embolization Alone for Giant Hepatic Hemangioma

    OpenAIRE

    Jun-Hui Sun; Chun-Hui Nie; Yue-Lin Zhang; Guan-Hui Zhou; Jing Ai; Tan-Yang Zhou; Tong-Yin Zhu; Ai-Bin Zhang; Wei-Lin Wang; Shu-Sen Zheng

    2015-01-01

    Giant hepatic hemangioma is a benign liver condition that may be treated using surgery. We studied the digital subtraction angiographic (DSA) characteristics of giant hepatic hemangioma, and the effectiveness of transcatheter arterial embolization (TAE) alone for its treatment. This was a retrospective study of 27 patients diagnosed with giant hepatic hemangioma and treated with TAE alone (using lipiodol mixed with pingyangmycin) at the Division of Hepatobiliary and Pancreatic Surgery, First ...

  15. Observing giant panda habitat and forage abundance from space

    OpenAIRE

    Wang, T.

    2009-01-01

    Giant pandas are obligate bamboo grazers. The bamboos favoured by giant pandas are typical forest understorey plants. Therefore, the availability and abundance of understorey bamboo is a key factor in determining the quantity and quality of giant panda food resources. However, there is little or no information about the spatial distribution or abundance of bamboo underneath the forest canopy, due to the limitations of traditional ground survey and remote sensing classification techniques. In ...

  16. Cystoperitoneal shunt for a giant intrathoracic meningocele under local anesthesia.

    Science.gov (United States)

    Tanaka, Kazumi; Shimizu, Kimihiro; Kakegawa, Seiichi; Oshima, Kiyohiro; Takeyoshi, Izumi

    2011-01-01

    Giant intrathoracic meningoceles are extremely rare, and the standard treatment for giant intrathoracic meningoceles remains controversial. We present the case of a patient with giant intrathoracic meningoceles associated with neurofibromatosis type I. Our patient had poor respiratory function because of the giant intrathoracic meningocele, so we performed a cystoperitoneal shunt under local anesthesia. We describe our cystoperitoneal shunt technique using an adjustable-pressure valve. This simple, minimally invasive treatment is a valuable alternative treatment option in patients at high operative risk, especially those with low respiratory function. Copyright © 2011 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

  17. Cytoskeletal control of nuclear arrangement in Langhans multinucleate giant cells.

    Science.gov (United States)

    Rigby, P J; Papadimitriou, J M

    1984-05-01

    Examination of the role of the cytoskeleton in macrophage polykarya (multinucleate giant cells) has established that microfilaments and microtubules are interrelated and contractile cytoskeletal components with opposing actions; when critically maintained at equilibrium, they are responsible for maintenance of the highly organized cellular architecture characteristic of Langhans type syncytia. Disruption of the function of these structures by in vitro incubation with cytochalasin B and/or colchicine can result in reversion to a cytoarchitecture which is more typical of the 'foreign body' multinucleate giant cell. These observations strongly reinforce previous suggestions that Langhans multinucleate giant cells are special, more highly organized forms than are 'foreign body' multinucleate giant cells.

  18. Two cases of giant pyogenic granuloma of scalp

    Directory of Open Access Journals (Sweden)

    B Satish Chandra

    2013-01-01

    Full Text Available Pyogenic granuloma is a benign vascular tumor of unknown etiology, though multiple factors play a role in its onset, e.g., trauma, chronic irritation, drugs etc., It is commonly seen in children and adolescents. Giant pyogenic granuloma is its atypical variant. We are presenting two cases of giant pyogenic granuloma, one, in a 28-year-old adult, presenting as a giant fluffy swelling of scalp and the other in a 11-year-old child, presenting as a giant ulcerated globular swelling of the scalp.

  19. Netgram: Visualizing Communities in Evolving Networks.

    Directory of Open Access Journals (Sweden)

    Raghvendra Mall

    Full Text Available Real-world complex networks are dynamic in nature and change over time. The change is usually observed in the interactions within the network over time. Complex networks exhibit community like structures. A key feature of the dynamics of complex networks is the evolution of communities over time. Several methods have been proposed to detect and track the evolution of these groups over time. However, there is no generic tool which visualizes all the aspects of group evolution in dynamic networks including birth, death, splitting, merging, expansion, shrinkage and continuation of groups. In this paper, we propose Netgram: a tool for visualizing evolution of communities in time-evolving graphs. Netgram maintains evolution of communities over 2 consecutive time-stamps in tables which are used to create a query database using the sql outer-join operation. It uses a line-based visualization technique which adheres to certain design principles and aesthetic guidelines. Netgram uses a greedy solution to order the initial community information provided by the evolutionary clustering technique such that we have fewer line cross-overs in the visualization. This makes it easier to track the progress of individual communities in time evolving graphs. Netgram is a generic toolkit which can be used with any evolutionary community detection algorithm as illustrated in our experiments. We use Netgram for visualization of topic evolution in the NIPS conference over a period of 11 years and observe the emergence and merging of several disciplines in the field of information processing systems.

  20. Evolving MEMS Resonator Designs for Fabrication

    Science.gov (United States)

    Hornby, Gregory S.; Kraus, William F.; Lohn, Jason D.

    2008-01-01

    Because of their small size and high reliability, microelectromechanical (MEMS) devices have the potential to revolution many areas of engineering. As with conventionally-sized engineering design, there is likely to be a demand for the automated design of MEMS devices. This paper describes our current status as we progress toward our ultimate goal of using an evolutionary algorithm and a generative representation to produce designs of a MEMS device and successfully demonstrate its transfer to an actual chip. To produce designs that are likely to transfer to reality, we present two ways to modify evaluation of designs. The first is to add location noise, differences between the actual dimensions of the design and the design blueprint, which is a technique we have used for our work in evolving antennas and robots. The second method is to add prestress to model the warping that occurs during the extreme heat of fabrication. In future we expect to fabricate and test some MEMS resonators that are evolved in this way.

  1. Netgram: Visualizing Communities in Evolving Networks

    Science.gov (United States)

    Mall, Raghvendra; Langone, Rocco; Suykens, Johan A. K.

    2015-01-01

    Real-world complex networks are dynamic in nature and change over time. The change is usually observed in the interactions within the network over time. Complex networks exhibit community like structures. A key feature of the dynamics of complex networks is the evolution of communities over time. Several methods have been proposed to detect and track the evolution of these groups over time. However, there is no generic tool which visualizes all the aspects of group evolution in dynamic networks including birth, death, splitting, merging, expansion, shrinkage and continuation of groups. In this paper, we propose Netgram: a tool for visualizing evolution of communities in time-evolving graphs. Netgram maintains evolution of communities over 2 consecutive time-stamps in tables which are used to create a query database using the sql outer-join operation. It uses a line-based visualization technique which adheres to certain design principles and aesthetic guidelines. Netgram uses a greedy solution to order the initial community information provided by the evolutionary clustering technique such that we have fewer line cross-overs in the visualization. This makes it easier to track the progress of individual communities in time evolving graphs. Netgram is a generic toolkit which can be used with any evolutionary community detection algorithm as illustrated in our experiments. We use Netgram for visualization of topic evolution in the NIPS conference over a period of 11 years and observe the emergence and merging of several disciplines in the field of information processing systems. PMID:26356538

  2. BOOK REVIEW: OPENING SCIENCE, THE EVOLVING GUIDE ...

    Science.gov (United States)

    The way we get our funding, collaborate, do our research, and get the word out has evolved over hundreds of years but we can imagine a more open science world, largely facilitated by the internet. The movement towards this more open way of doing and presenting science is coming, and it is not taking hundreds of years. If you are interested in these trends, and would like to find out more about where this is all headed and what it means to you, consider downloding Opening Science, edited by Sönke Bartling and Sascha Friesike, subtitled The Evolving Guide on How the Internet is Changing Research, Collaboration, and Scholarly Publishing. In 26 chapters by various authors from a range of disciplines the book explores the developing world of open science, starting from the first scientific revolution and bringing us to the next scientific revolution, sometimes referred to as “Science 2.0”. Some of the articles deal with the impact of the changing landscape of how science is done, looking at the impact of open science on Academia, or journal publishing, or medical research. Many of the articles look at the uses, pitfalls, and impact of specific tools, like microblogging (think Twitter), social networking, and reference management. There is lots of discussion and definition of terms you might use or misuse like “altmetrics” and “impact factor”. Science will probably never be completely open, and Twitter will probably never replace the journal article,

  3. Seismology of Giant Planets: General Overview and Results from the Kepler K2 Observations of Neptune

    Directory of Open Access Journals (Sweden)

    Gaulme Patrick

    2017-01-01

    Full Text Available For this invited contribution, I was asked to give an overview about the application of helio and aster-oseismic techniques to study the interior of giant planets, and to specifically present the recent observations of Neptune by Kepler K2. Seismology applied to giant planets could drastically change our understanding of their deep interiors, as it has happened with the Earth, the Sun, and many main-sequence and evolved stars. The study of giant planets' composition is important for understanding both the mechanisms enabling their formation and the origins of planetary systems, in particular our own. Unfortunately, its determination is complicated by the fact that their interior is thought not to be homogeneous, so that spectroscopic determinations of atmospheric abundances are probably not representative of the planet as a whole. Instead, the determination of their composition and structure must rely on indirect measurements and interior models. Giant planets are mostly fluid and convective, which makes their seismology much closer to that of solar-like stars than that of terrestrial planets. Hence, helioseismology techniques naturally transfer to giant planets. In addition, two alternative methods can be used: photometry of the solar light reflected by planetary atmospheres, and ring seismology in the specific case of Saturn. The current decade has been promising thanks to the detection of Jupiter's acoustic oscillations with the ground-based imaging-spectrometer SYMPA and indirect detection of Saturn's f-modes in its rings by the NASA Cassini orbiter. This has motivated new projects of ground-based and space-borne instruments that are under development. The K2 observations represented the first opportunity to search for planetary oscillations with visible photometry. Despite the excellent quality of K2 data, the noise level of the power spectrum of the light curve was not low enough to detect Neptune's oscillations. The main results from the

  4. Seismology of Giant Planets: General Overview and Results from the Kepler K2 Observations of Neptune

    Science.gov (United States)

    Gaulme, Patrick

    2017-10-01

    For this invited contribution, I was asked to give an overview about the application of helio and aster-oseismic techniques to study the interior of giant planets, and to specifically present the recent observations of Neptune by Kepler K2. Seismology applied to giant planets could drastically change our understanding of their deep interiors, as it has happened with the Earth, the Sun, and many main-sequence and evolved stars. The study of giant planets' composition is important for understanding both the mechanisms enabling their formation and the origins of planetary systems, in particular our own. Unfortunately, its determination is complicated by the fact that their interior is thought not to be homogeneous, so that spectroscopic determinations of atmospheric abundances are probably not representative of the planet as a whole. Instead, the determination of their composition and structure must rely on indirect measurements and interior models. Giant planets are mostly fluid and convective, which makes their seismology much closer to that of solar-like stars than that of terrestrial planets. Hence, helioseismology techniques naturally transfer to giant planets. In addition, two alternative methods can be used: photometry of the solar light reflected by planetary atmospheres, and ring seismology in the specific case of Saturn. The current decade has been promising thanks to the detection of Jupiter's acoustic oscillations with the ground-based imaging-spectrometer SYMPA and indirect detection of Saturn's f-modes in its rings by the NASA Cassini orbiter. This has motivated new projects of ground-based and space-borne instruments that are under development. The K2 observations represented the first opportunity to search for planetary oscillations with visible photometry. Despite the excellent quality of K2 data, the noise level of the power spectrum of the light curve was not low enough to detect Neptune's oscillations. The main results from the K2 observations are

  5. The evolving universe and the origin of life the search for our cosmic roots

    CERN Document Server

    Teerikorpi, Pekka; Lehto, Harry; Chernin, Arthur; Byrd, Gene; Lehto, K

    2008-01-01

    Sir Isaac Newton famously said, regarding his discoveries, "If I have seen further it is by standing upon the shoulders of giants." The Evolving Universe and the Origin of Life describes, complete with fascinating biographical details of the thinkers involved, the ascent to the metaphorical shoulders accomplished by the greatest minds in history. For the first time, a single book can take the reader on a journey through the history of the universe as interpreted by the expanding body of knowledge of humankind. From subatomic particles to the protein chains that form life, and expanding in scale to the entire universe, this book covers the science that explains how we came to be. The Evolving Universe and the Origin of Life contains a great breadth of knowledge, from astronomy to physics, from chemistry to biology. It includes over 350 figures that enhance the comprehension of concepts both basic and advanced, and is a non-technical, easy-to-read text at an introductory college level that is ideal for anyone i...

  6. Intraplate mafic magmatism, degasification, and deposition of mercury: the giant Almadén mercury deposit (Spain) revisited

    OpenAIRE

    Lillo Ramos, Francisco Javier; Higueras Higueras, Pablo Leon; Morata Cespedes, Diego; Oyarzun Muñoz, Roberto

    2013-01-01

    The giant Almadén mercury deposit (Spain) is hosted by the Lower Silurian Criadero Quartzite; in turn this ore-bearing rock unit is cross-cut by the so-called Frailesca unit, a diatreme body of basaltic composition. The geochemical characteristics of the Silurian to Devonian Almadén District volcanic units indicate that these rocks originated from an enriched, evolving mantle source that ultimately yielded basanites?nephelinites to yolites, through olivine-basalts, pyroxene-basalts, trachybas...

  7. Evolvability as a Quality Attribute of Software Architectures

    NARCIS (Netherlands)

    Ciraci, S.; van den Broek, P.M.; Duchien, Laurence; D'Hondt, Maja; Mens, Tom

    We review the definition of evolvability as it appears on the literature. In particular, the concept of software evolvability is compared with other system quality attributes, such as adaptability, maintainability and modifiability.

  8. Measuring Precise Radii of Giants Orbiting Giants to Distinguish Between Planet Evolution Models

    Science.gov (United States)

    Grunblatt, Samuel; Huber, Daniel; Lopez, Eric; Gaidos, Eric; Livingston, John

    2017-10-01

    Despite more than twenty years since the initial discovery of highly irradiated gas giant planets, the mechanism for planet inflation remains unknown. However, proposed planet inflation mechanisms can now be separated into two general classes: those which allow for post-main sequence planet inflation by direct irradiation from the host star, and those which only allow for slowed cooling of the planet over its lifetime. The recent discovery of two inflated warm Jupiters orbiting red giant stars with the NASA K2 Mission allows distinction between these two classes, but uncertainty in the planet radius blurs this distinction. Observing transits of these planets with the Spitzer Space Telescope would reduce stellar variability and thus planet radius uncertainties by approximately 50% relative to K2, allowing distinction between the two planet inflation model classes at a 3-sigma level. We propose to observe one transit of both known warm Jupiters orbiting red giant stars, K2-97b and EPIC228754001.01, to distinguish between planet model inflation classes and measure the planetary heating efficiency to 3-sigma precision. These systems are benchmarks for the upcoming NASA TESS Mission, which is predicted to discover an order of magnitude more red giant planet systems after launching next year.

  9. Tracking correlated, simultaneously evolving target populations, II

    Science.gov (United States)

    Mahler, Ronald

    2017-05-01

    This paper is the sixth in a series aimed at weakening the independence assumptions that are typically presumed in multitarget tracking. Earlier papers investigated Bayes …lters that propagate the correlations between two evolving multitarget systems. Last year at this conference we attempted to derive PHD …lter-type approximations that account for both spatial correlation and cardinality correlation (i.e., correlation between the target numbers of the two systems). Unfortunately, this approach required heuristic models of both clutter and target appearance in order to incorporate both spatial and cardinality correlation. This paper describes a fully rigorous approach- provided, however, that spatial correlation between the two populations is ignored and only their cardinality correlations are taken into account. We derive the time-update and measurement-update equations for a CPHD …lter describing the evolution of such correlated multitarget populations.

  10. Resiliently evolving supply-demand networks.

    Science.gov (United States)

    Rubido, Nicolás; Grebogi, Celso; Baptista, Murilo S

    2014-01-01

    The ability to design a transport network such that commodities are brought from suppliers to consumers in a steady, optimal, and stable way is of great importance for distribution systems nowadays. In this work, by using the circuit laws of Kirchhoff and Ohm, we provide the exact capacities of the edges that an optimal supply-demand network should have to operate stably under perturbations, i.e., without overloading. The perturbations we consider are the evolution of the connecting topology, the decentralization of hub sources or sinks, and the intermittence of supplier and consumer characteristics. We analyze these conditions and the impact of our results, both on the current United Kingdom power-grid structure and on numerically generated evolving archetypal network topologies.

  11. A local-world evolving hypernetwork model

    Science.gov (United States)

    Yang, Guang-Yong; Liu, Jian-Guo

    2014-01-01

    Complex hypernetworks are ubiquitous in the real system. It is very important to investigate the evolution mechanisms. In this paper, we present a local-world evolving hypernetwork model by taking into account the hyperedge growth and local-world hyperedge preferential attachment mechanisms. At each time step, a newly added hyperedge encircles a new coming node and a number of nodes from a randomly selected local world. The number of the selected nodes from the local world obeys the uniform distribution and its mean value is m. The analytical and simulation results show that the hyperdegree approximately obeys the power-law form and the exponent of hyperdegree distribution is γ = 2 + 1/m. Furthermore, we numerically investigate the node degree, hyperedge degree, clustering coefficient, as well as the average distance, and find that the hypernetwork model shares the scale-free and small-world properties, which shed some light for deeply understanding the evolution mechanism of the real systems.

  12. The Evolving Theory of Evolutionary Radiations.

    Science.gov (United States)

    Simões, M; Breitkreuz, L; Alvarado, M; Baca, S; Cooper, J C; Heins, L; Herzog, K; Lieberman, B S

    2016-01-01

    Evolutionary radiations have intrigued biologists for more than 100 years, and our understanding of the patterns and processes associated with these radiations continues to grow and evolve. Recently it has been recognized that there are many different types of evolutionary radiation beyond the well-studied adaptive radiations. We focus here on multifarious types of evolutionary radiations, paying special attention to the abiotic factors that might trigger diversification in clades. We integrate concepts such as exaptation, species selection, coevolution, and the turnover-pulse hypothesis (TPH) into the theoretical framework of evolutionary radiations. We also discuss other phenomena that are related to, but distinct from, evolutionary radiations that have relevance for evolutionary biology. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Epidemic spreading on evolving signed networks

    CERN Document Server

    Saeedian, M; Jafari, G R; Kertesz, J

    2016-01-01

    Most studies of disease spreading consider the underlying social network as obtained without the contagion, though epidemic influences peoples willingness to contact others: A friendly contact may be turned to unfriendly to avoid infection. We study the susceptible-infected (SI) disease spreading model on signed networks, in which each edge is associated with a positive or negative sign representing the friendly or unfriendly relation between its end nodes. In a signed network, according to Heiders theory, edge signs evolve such that finally a state of structural balance is achieved, corresponding to no frustration in physics terms. However, the danger of infection affects the evolution of its edge signs. To describe the coupled problem of the sign evolution and disease spreading, we generalize the notion of structural balance by taking into account the state of the nodes. We introduce an energy function and carry out Monte-Carlo simulations on complete networks to test the energy landscape, where we find loc...

  14. Finch: A System for Evolving Java (Bytecode)

    Science.gov (United States)

    Orlov, Michael; Sipper, Moshe

    The established approach in genetic programming (GP) involves the definition of functions and terminals appropriate to the problem at hand, after which evolution of expressions using these definitions takes place. We have recently developed a system, dubbed FINCH (Fertile Darwinian Bytecode Harvester), to evolutionarily improve actual, extant software, which was not intentionally written for the purpose of serving as a GP representation in particular, nor for evolution in general. This is in contrast to existing work that uses restricted subsets of the Java bytecode instruction set as a representation language for individuals in genetic programming. The ability to evolve Java programs will hopefully lead to a valuable new tool in the software engineer's toolkit.

  15. The Chemical Composition Contrast between M3 and M13 Revisited: New Abundances for 28 Giant Stars in M3

    Science.gov (United States)

    Sneden, Christopher; Kraft, Robert P.; Guhathakurta, Puragra; Peterson, Ruth C.; Fulbright, Jon P.

    2004-04-01

    abundant isotopes of Mg. This points to a scenario in which these abundance ratios arose in the ejected material of 3-6 Msolar cluster stars, material that was then used to form the atmospheres of the presently evolving low-mass cluster stars. It also suggests that the low oxygen abundance seen among the most evolved M13 giants arose in hot bottom O-to-N processing in these same intermediate-mass cluster stars. Thus, mixing is required by the dependence of some abundance ratios on luminosity, but an earlier nucleosynthesis process in a hotter environment than giants or main-sequence stars is required by the variations previously seen in stars near the main sequence. The nature and the site of the earlier process is constrained but not pinpointed by the observed Mg isotopic ratio. Based on data obtained at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration. The Observatory was made possible by the generous financial support of the W. M. Keck Foundation. The authors wish to recognize and acknowledge the very significant cultural role and reverence that the summit of Mauna Kea has always had within the indigenous Hawaiian community. We are most fortunate to have the opportunity to conduct observations from this mountain.

  16. Exact and approximate calculation of giant resonances

    Energy Technology Data Exchange (ETDEWEB)

    Vertse, T. [Magyar Tudomanyos Akademia, Debrecen (Hungary). Atommag Kutato Intezete; Liotta, R.J. [Royal Inst. of Tech., Stockholm (Sweden); Maglione, E. [Padua Univ. (Italy). Ist. di Fisica

    1995-02-13

    Energies, sum rules and partial decay widths of giant resonances in {sup 208}Pb are calculated solving exactly the continuum RPA equations corresponding to a central Woods-Saxon potential. For comparison an approximate treatment of those quantities in terms of pole expansions of the Green function (Berggren and Mittag-Leffler) is also performed. It is found that the approximated results agree well with the exact ones. Comparison with experimental data is made and a search for physically meaningful resonances is carried out. ((orig.))

  17. Giant cell tumour of talar body.

    Directory of Open Access Journals (Sweden)

    Bapat M

    2000-04-01

    Full Text Available Giant cell tumour (osteoclastoma of talar bone is a rare entity and is seen more commonly in the third decade of life. We report this disease entity in a 17-years-old girl. The patient presented with painful swelling of the left ankle with an osteolytic lesion in the talus on conventional radiographs. Intralesional curettage and autologous bone grafting was performed following which patient′s pain and swelling disappeared. Complete range of movement at the ankle joint was regained with minimal restriction at the subtalar joint. There is no evidence of relapse at six months follow up.

  18. Giant fibroepithelial polyp of the vulva

    Directory of Open Access Journals (Sweden)

    Selma Korkmaz

    2014-12-01

    Full Text Available Fibroepithelial polyps are among common benign skin lesions. They are usually small and skin-colored lesions and are located frequently in the axilla and neck. They are rarely seen in the vulva. There is a small number of cases that reach the giant sizes in this area in the literature. A 20-year-old female patient presented with a pedunculated mass measuring 25 cm in diameter, localized to the right labium majus. The lesion was excised and the histopathological diagnosis was fibroepithelial polyp. We present this case because of it is the largest reported fibroepithelial polyp of the vulva in the literature.

  19. Lyme carditis mimicking giant cell arteritis

    Directory of Open Access Journals (Sweden)

    Krati Chauhan

    2015-10-01

    Full Text Available Presenting an interesting case of a patient who complained of myalgias, fatigue, headache, jaw claudication and scalp tenderness. Patient’s physical examination was unremarkable. Laboratory findings showed elevated erythrocyte sedimentation rate and C-reactive protein, bilateral temporal artery biopsy results were negative and first degree atrioventricular block was seen on electrocardiogram. Serology for Borrelia burgdorferi was positive; patient was diagnosed with Lyme carditis and treated with doxycycline. Lyme is a tick-borne, multi-system disease and occasionally its presentation may mimic giant cell arteritis. On follow-up there was complete resolution of symptoms and electrocardiogram findings.

  20. Giant Submandibular Calculus Eroding Oral Cavity Mucosa.

    Science.gov (United States)

    Lim, Eng Haw; Nadarajah, Sanjeevan; Mohamad, Irfan

    2017-09-01

    Sialolithiasis is the formation of calculi or sialoliths in the salivary gland. It is the most common benign condition of the salivary gland. Sialolithiasis can occur in all salivary glands. The submandibular gland is most commonly affected followed by the parotid gland. Calculi commonly measure less than 10 mm. Calculi of more than 15 mm are termed giant salivary gland calculi and are infrequently reported in the literature. Here, we report a case of unusually large submandibular gland calculus of 5 cm in greatest dimension which caused erosion of the oral cavity.

  1. New Observations of the Giant's Churches

    Science.gov (United States)

    Ridderstad, Marianna

    2015-05-01

    Orientations of the axes and gates of 49 Giant's Churches (GCs) were examined. Orientations to both solar and lunar events were discovered. The results especially suggest the importance of full moon events. Comparison between the orientations of the southern and the northern GCs did not reveal great differences. The majority of the GCs are situated on the eastern or southern sides of their ridges, and most of them enclose or are surrounded by cairns. Based on parallels to other North European Neolithic cultures, it is proposed that the GCs went through several phases of construction, the last phase being probably related to ritual activities.

  2. Giant Malignant Pheochromocytoma with Palpable Rib Metastases

    Directory of Open Access Journals (Sweden)

    Esat Korgali

    2014-01-01

    Full Text Available Pheochromocytoma is a rare and usually benign neuroendocrine neoplasm. Only 10% of all these tumors are malignant and there are no definitive histological or cytological criteria of malignancy. Single malignancy criteria are the presence of advanced locoregional disease or metastases. We report a case, with a giant retroperitoneal tumor having multiple metastases including palpable rib metastases, who was diagnosed as a malignant pheochromocytoma. The patient was treated with surgery. The literature was reviewed to evaluate tumor features and current diagnostic and therapeutic approaches for patients with metastatic or potentially malignant pheochromocytoma.

  3. Wood of Giant Sequoia: properties and unique characteristics

    Science.gov (United States)

    Douglas D. Piirto

    1986-01-01

    Wood properties of giant sequoia (Sequoia gigantea [Lindl.] Decne.) were compared with those for other coniferous tree species. Wood properties such as specific gravity, various mechanical properties, extractive content, and decay resistance of young-growth giant sequoia are comparable to or more favorable than those of coast redwood (...

  4. Chemical Analysis of Asymptotic Giant Branch Stars in M62

    NARCIS (Netherlands)

    Lapenna, E.; Mucciarelli, A.; Ferraro, F. R.; Origlia, L.; Lanzoni, B.; Massari, D.; Dalessandro, E.

    2015-01-01

    We have collected UVES-FLAMES high-resolution spectra for a sample of 6 asymptotic giant branch (AGB) and 13 red giant branch (RGB) stars in the Galactic globular cluster (GC) M62 (NGC 6266). Here we present the detailed abundance analysis of iron, titanium, and light elements (O, Na, Mg, and Al).

  5. Giant bladder diverticulum : A rare cause of bladder outlet ...

    African Journals Online (AJOL)

    Giant bladder diverticula are rare causes of bladder outlet obstruction in children and have rarely been reported. In this paper, we present three children with giant bladder diverticula who presented with bladder outlet obstruction within a year. Micturating cystourethrogram is important for investigating bladder outlet ...

  6. Growth, Age Determination and Longevity in the Giant African Snail ...

    African Journals Online (AJOL)

    Growth, Age Determination and Longevity in the Giant African Snail Archachatina marginata (Swainson) ... The implication of this studies for snail culture is that, in semi-intensive systems with minimal input, giant snails can be kept up to 11/2 years for them to reach competitive market sizes. Key Words: Archachatina ...

  7. Giant Anal Condyloma Acuminatum in Childhood: A Case Report ...

    African Journals Online (AJOL)

    The authors report a case of anal giant condyloma acuminatum present for 10 years in a 14 year old. The giant tumor was responsible for difficulty in the sitting and difficulty with defecation. Surgical excision was a little limited in order to conserve the anal sphincter. Cauterization with diathermy was done on the remaining ...

  8. Differential substrate affinity between two giant clam species ...

    African Journals Online (AJOL)

    Giant clams have been mostly reported in the South Paci c and Indian Ocean. The aim of this study was to com- pare the substrate a nity between two species of giant clams, Tridacna maxima and T. squamosa. Field surveys were carried out in April and May 2016 within the reef areas of three geographically di erent sites ...

  9. surgical management of aggressive synchronous jaw central giant ...

    African Journals Online (AJOL)

    2012-08-08

    Aug 8, 2012 ... include the aneurysmal bone cyst, giant cell tumor, hyperparathyroidism and cherubism (3, 10). Their relationship to each other, however, is ill-defined. Histologically all of the giant cell lesions appear identical and usually cannot be distinguished on light microscopy alone (3,10). This perhaps highlights the ...

  10. Giant cell reparative granuloma of the hallux following enchondroma ...

    African Journals Online (AJOL)

    Giant cell reparative granuloma (GCRG) is a rare, benign intra osseous lytic lesion occurring especially in gnathis bone but also seen in feet and hands. It has similar clinical and radiological presentations than giant cell tumor, chondroblastoma, aneurysmal bone cyst, and hyperparathyroidism brown tumors but with specific ...

  11. Management of Giant Cell Tumour: A Nigerian Experience | Eyesan ...

    African Journals Online (AJOL)

    Giant cell tumours (GCT) are the commonest bone tumours worldwide. It is rarely malignant but when it does it progresses to fibrosarcoma with high mortality. Otherwise it causes poor cosmesis, disability and pathological fractures. A total of 19 cases of histologically established Giant cell tumour of the bone were reviewed ...

  12. Vernal keratoconjunctivitis with giant papillae on the inferior tarsal conjunctiva.

    Science.gov (United States)

    Asada, Yosuke; Ebihara, Nobuyuki; Funaki, Toshinari; Yokoi, Norihiko; Murakami, Akira; Matsuda, Akira

    2014-01-01

    In vernal keratoconjunctivitis (VKC), giant papillae are commonly observed on the superior tarsal conjunctiva. We found 3 cases of giant papillae on the inferior tarsal conjunctiva, and diagnosed them as being VKC based on their clinical and histopathological features. Three patients with inferior tarsal giant papillae were studied. In 2 patients, the giant papillae were resected for therapeutic purposes. Immunohistochemical analysis was carried out by indirect immunofluorescent staining using anti-CD3, anti-CD20, anti-CD35 antibodies. In all 3 patients, giant papilla formation was observed on the inferior lid margin. Clusters of CD20 B lymphocytes with CD35 follicular dendritic cells, and CD3 marginal zone T lymphocytes, common features of lymphoid neogenesis, were observed. In 2 patients, typical giant papillary formation was also observed on the superior tarsal conjunctiva. In all the patients, topical dexamethasone and tacrolimus treatments were found to be effective. The giant papillae of VKC can occur not only on the superior tarsal conjunctiva but also on the inferior tarsal conjunctiva. The possibility of the presence of giant papillae on the inferior tarsal conjunctiva should be considered in the clinical examination of patients with VKC.

  13. The potential significance of binovular follicles and binucleate giant ...

    Indian Academy of Sciences (India)

    No pregnancy was achieved after transfer of an embryo from a binovular follicle. Binucleate giant oocytes have been observed sporadically but a few reports suggest an incidence of up to 0.3% of all gametes retrieved. Extensive studies performed by two independent centres demonstrated that giant oocytes are diploid at ...

  14. Giant lipoma of the right gluteal region | Adebayo | Journal of ...

    African Journals Online (AJOL)

    Lipomas are the most common benign mesenchymal tumors and can arise in any location where fat is found. They could present as a tiny swelling or as an enormous mass in a body region. When they are more than 10 cm in their widest dimension or greater than 1 kg in weight, they are called giant lipomas. Giant lipomas ...

  15. Giant fibroadenoma presenting like fungating breast cancer in a ...

    African Journals Online (AJOL)

    Background: Giant fibroadenoma of the breast is a rare benign breast tumour which seldom grows to a giant size, it is even rarer for this benign tumour to grow rapidly, ulcerate spontaneously and present like a fungating breast tumour in a way mimicking breast cancer. Case presentation: This is a presentation of a 14 year ...

  16. CASE REPORT: A GIANT URINARY BLADDER STONE IN A ...

    African Journals Online (AJOL)

    A vesical calculus weighing more than 100g is categorized as a giant urinary bladder stone. Male preponderance for urinary bladder calculi is well known. A rare case of a giant urinary bladder calculus weighing 1200g and occurring in a female patient is reported. The stone was removed by open vesicolithotomy.

  17. Giant Osteoma of the Frontoethmoidal Sinus: A Case Report | Shehu ...

    African Journals Online (AJOL)

    Giant or large osteomas of the skull are uncommon. This is a report of a 14-year old girl presenting with a giant osteoma of the frontoethmoidal sinus. The osteoma was completely excised at limited craniectomy. There has been no recurrence at 2 years of follow up. (Nig J Surg Res 2001; 3: 188 – 190) KEY WORDS: Skull ...

  18. detection by polymerase chain reaction (PCR) in Chinese giant ...

    African Journals Online (AJOL)

    A disease in farmed Chinese giant salamander (Andrias davidianus) was a common event, being an economically important threat for Chinese farms. Based on the clinical signs, epizootiology and pathogens belonging to the genus, Ranavirus was suspected as the possible etiology. Although in a cultured Chinese giant ...

  19. Outcomes of conservative treatment of giant omphaloceles with ...

    African Journals Online (AJOL)

    Background: The surgical management of giant omphalocele is a surgical challenge with high mortality and morbidity in our country due to the absence of neonatal resuscitation. This study evaluates conservative management of giant omphalocele with dissodic 2% aqueous eosin. Materials and Methods: In the period from ...

  20. Surgical treatment of giant haemangioma of the liver

    NARCIS (Netherlands)

    Brouwers, MAM; Peeters, PMJG; de Jong, KP; Haagsma, EB; Klompmaker, IJ; Bijleveld, CMA; Zwaveling, JH; Slooff, MJH

    Background The treatment of giant symptomatic haemangioma of the liver is still controversial. This retrospective study reviewed the results of surgical treatment. Methods Twenty-eight patients with symptomatic giant haemangioma of the liver were treated by liver resection (n = 24) or liver

  1. Unusual giant prostatic urethral calculus | Bello | Journal of Surgical ...

    African Journals Online (AJOL)

    Giant vesico-prostatic urethral calculus is uncommon. Urethral stones rarely form primarily in the urethra, and they are usually associated with urethral strictures, posterior urethral valve or diverticula. We report a case of a 32-year-old man with giant vesico-prostatic (collar-stud) urethral stone presenting with sepsis and ...

  2. Giant Calculus In The Mouth Of Partially Edentulous Woman, (Case ...

    African Journals Online (AJOL)

    Objective: This case report is to create awareness of the presence of giant calculus in the mouth, the possible causes and its prevention. Report: This describes the oral condition of a partially edentulous woman with a giant calculus in the mouth. It highlights the effect of such an enormous calculus in the oral cavity.

  3. BOOK REVIEW: Dancing with the Giants: China, India, and the ...

    African Journals Online (AJOL)

    BOOK REVIEW: Dancing with the Giants: China, India, and the Global Economy. ... Economic and Policy Review ... The emergence of China and India as the two fastest growing giants on the global economic stage denotes the need for other developing countries to improve their investment climates and invest heavily on ...

  4. Nutritional evaluation of the giant grassropper (Zonocerus variegatus)

    African Journals Online (AJOL)

    The biological value of giant grasshopper protein (Zonocerus variegatus) was evaluated by comparing the weight gained, food efficiency ratio (FER), protein efficiency ratio (PER) of rats fed standard laboratory chow with that of rats fed giant grasshopper, Soyabean(Glycine max) and crayfish. The effect of high fibre content ...

  5. Pathogenicity of Trypanosoma brucei in African giant rats ...

    African Journals Online (AJOL)

    Pathogenicity of Trypanosoma brucei in African giant rats ( Cricetomys gambianus , Water House) ... The course of trypanosomosis was investigated over a period of two weeks in six African giant rats (Cricetomys gambianus) experimentally infected with Trypanosoma brucei. Six other rats served as uninfected control.

  6. EG And: Providing the Missing Link Required for Modelling Red Giant Mass-loss

    Science.gov (United States)

    Espey, Brian

    2009-07-01

    For the majority of red giant stars the basic mass-loss processes at work are unknown. Indeed, for stars of spectral types between K0 III and M5-M6 III, much remains unknown about the regions above the visible photosphere and the transportation of the processed material outwards to the ISM. Eclipsing symbiotic binary systems, consisting of an evolved giant in orbit with a white dwarf, provide an opportunity to take advantage of the finite size of the hot component to probe different levels of the chromosphere and wind acceleration region in absorption. This provides spatially resolved thermal, ionisation and dynamic information on the wind which can then be compared against predictions of hydrodynamical stellar atmosphere codes. The symbiotic binary EG And can be considered as a rosetta stone for understanding the winds of these objects. The system is ideal on a number of counts for utilising the ultraviolet eclipse of the white dwarf {WD} component to probe, layer-by-layer, the thermal and dynamic conditions at the very base of the wind and chromosphere of the RG. This information is vital for constraining, testing and calibrating the new generation of cool giant wind+chromosphere models and is not possible to obtain for isolated RGs. This team has studied the UV eclipses of this system in depth and detail, however in order to definitively constrain the wind acceleration profile and identify the location of the temperature rise just above the photosphere we require 4 STIS E140M observations of EG And at specific orbital phases. We are also requesting a E230M observation of an isolated spectral standard, corresponding to the RG inthe binary, which will help place the EG And results into the context of the general RG population from analysis of the MgII wind diagnostic lines.

  7. Pulsations of intermediate-mass stars on the asymptotic giant branch

    Science.gov (United States)

    Fadeyev, Yu. A.

    2017-09-01

    Evolutionary tracks from the zero age main sequence to the asymptotic giant branch were computed for stars with initial masses 2 M ⊙ ≤ M ZAMS ≤ 5 M ⊙ and metallicity Z = 0.02. Some models of evolutionary sequences were used as initial conditions for equations of radiation hydrodynamics and turbulent convection describing radial stellar pulsations. The early asymptotic giant branch stars are shown to pulsate in the fundamental mode with periods 30 day ≲ Π ≲ 400day. The rate of period change gradually increases as the star evolves but is too small to be detected (Π˙/Π < 10-5 yr-1). Pulsation properties of thermally pulsing AGB stars are investigated on time intervals comprising 17 thermal pulses for evolutionary sequences with initial masses M ZAMS = 2 M ⊙ and 3 M ⊙ and 6 thermal pulses for M ZAMS = 4 M ⊙ and 5 M ⊙. Stars with initial masses M ZAMS ≤ 3 M ⊙ pulsate either in the fundamental mode or in the first overtone, whereas more massive red giants ( M ZAMS ≥ 4 M ⊙) pulsate in the fundamental mode with periods Π ≲ 103 day. Most rapid pulsation period change with rate -0.02 yr-1 ≲ Π˙/Π ≲ -0.01 yr-1 occurs during decrease of the surface luminosity after the maximum of the luminosity in the helium shell source. The rate of subsequent increase of the period is Π˙/Π ≲ 5 × 10-3 yr-1.

  8. Metastatic giant basal cell carcinoma: a case report.

    Science.gov (United States)

    Bellahammou, Khadija; Lakhdissi, Asmaa; Akkar, Othman; Rais, Fadoua; Naoual, Benhmidou; Elghissassi, Ibrahim; M'rabti, Hind; Errihani, Hassan

    2016-01-01

    Basal cell carcinoma is the most common skin cancer, characterised by a slow growing behavior, metastasis are extremely rare, and it occurs in less than 0, 1% of all cases. Giant basal cell carcinoma is a rare form of basal cell carcinoma, more aggressive and defined as a tumor measuring more than 5 cm at its largest diameter. Only 1% of all basal cell carcinoma develops to a giant basal cell carcinoma, resulting of patient's negligence. Giant basal cell carcinoma is associated with higher potential of metastasis and even death, compared to ordinary basal cell carcinoma. We report a case of giant basal cell carcinoma metastaticin lung occurring in a 79 years old male patient, with a fatal evolution after one course of systemic chemotherapy. Giant basal cell carcinoma is a very rare entity, early detection of these tumors could prevent metastasis occurrence and improve the prognosis of this malignancy.

  9. Reactor vibration reduction based on giant magnetostrictive materials

    Directory of Open Access Journals (Sweden)

    Yan Rongge

    2017-05-01

    Full Text Available The vibration of reactors not only produces noise pollution, but also affects the safe operation of reactors. Giant magnetostrictive materials can generate huge expansion and shrinkage deformation in a magnetic field. With the principle of mutual offset between the giant magnetostrictive force produced by the giant magnetostrictive material and the original vibration force of the reactor, the vibration of the reactor can be reduced. In this paper, magnetization and magnetostriction characteristics in silicon steel and the giant magnetostrictive material are measured, respectively. According to the presented magneto-mechanical coupling model including the electromagnetic force and the magnetostrictive force, reactor vibration is calculated. By comparing the vibration of the reactor with different inserted materials in the air gaps between the reactor cores, the vibration reduction effectiveness of the giant magnetostrictive material is validated.

  10. Giant Planets Can Act as Stabilizing Agents on Debris Disks

    Energy Technology Data Exchange (ETDEWEB)

    Muñoz-Gutiérrez, M. A.; Pichardo, B.; Peimbert, A., E-mail: mmunoz.astro@gmail.com [Instituto de Astronomía, Universidad Nacional Autónoma de México, Apdo. postal 70-264 Ciudad Universitaria, México (Mexico)

    2017-07-01

    We have explored the evolution of a cold debris disk under the gravitational influence of dwarf-planet-sized objects (DPs), both in the presence and absence of an interior giant planet. Through detailed long-term numerical simulations, we demonstrate that when the giant planet is not present, DPs can stir the eccentricities and inclinations of disk particles, in linear proportion to the total mass of the DPs; on the other hand, when the giant planet is included in the simulations, the stirring is approximately proportional to the mass squared. This creates two regimes: below a disk mass threshold (defined by the total mass of DPs), the giant planet acts as a stabilizing agent of the orbits of cometary nuclei, diminishing the effect of the scatterers; above the threshold, the giant contributes to the dispersion of the particles.

  11. Reactor vibration reduction based on giant magnetostrictive materials

    Science.gov (United States)

    Rongge, Yan; Weiying, Liu; Yuechao, Wu; Menghua, Duan; Xiaohong, Zhang; Lihua, Zhu; Ling, Weng; Ying, Sun

    2017-05-01

    The vibration of reactors not only produces noise pollution, but also affects the safe operation of reactors. Giant magnetostrictive materials can generate huge expansion and shrinkage deformation in a magnetic field. With the principle of mutual offset between the giant magnetostrictive force produced by the giant magnetostrictive material and the original vibration force of the reactor, the vibration of the reactor can be reduced. In this paper, magnetization and magnetostriction characteristics in silicon steel and the giant magnetostrictive material are measured, respectively. According to the presented magneto-mechanical coupling model including the electromagnetic force and the magnetostrictive force, reactor vibration is calculated. By comparing the vibration of the reactor with different inserted materials in the air gaps between the reactor cores, the vibration reduction effectiveness of the giant magnetostrictive material is validated.

  12. Giant magnons of string theory in the lambda background

    Science.gov (United States)

    Appadu, Calan; Hollowood, Timothy J.; Miramontes, J. Luis; Price, Dafydd; Schmidtt, David M.

    2017-07-01

    The analogues of giant magnon configurations are studied on the string world sheet in the lambda background. This is a discrete deformation of the AdS5× S 5 background that preserves the integrability of the world sheet theory. Giant magnon solutions are generated using the dressing method and their dispersion relation is found. This reduces to the usual dyonic giant magnon dispersion relation in the appropriate limit and becomes relativistic in another limit where the lambda model becomes the generalized sine-Gordon theory of the Pohlmeyer reduction. The scattering of giant magnons is then shown in the semi-classical limit to be described by the quantum S-matrix that is a quantum group deformation of the conventional giant magnon S-matrix. It is further shown that in the small g limit, a sector of the S-matrix is related to the XXZ spin chain whose spectrum matches the spectrum of magnon bound states.

  13. A giant internal carotid artery aneurysm: case report

    Directory of Open Access Journals (Sweden)

    Dilcan Kotan

    2013-12-01

    Full Text Available Aneurysms greater than 2.5 cm in diameter are classified as giant aneurysms and represent 5-8% of all intracranial aneurysms. Giant intracranial aneurysms demonstrates the clinical course with symptoms related to subarachnoid haemorrhage, mass effect, thromboembolism and seizures. Not only because of their large sizes, but also because of their usually wide and calcified aneurysm neck, existing thrombus within and its proximity to cranial nerves; giant aneurysms causes serious surgical difficulties. Giant aneurysms of the anterior intracranial circulation are rare, slowly progressive vascular abnormalities, often presenting with neuro-ophthalmological symptoms before they rupture. Herein, a case of 77-year-old woman with a giant aneurysm originated from intracavernous segment of internal carotid artery detected in magnetic resonance angiography who presented symptoms due to affected multiple cranial nerves related to mass effect.

  14. Extinction implications of a chenopod browse diet for a giant Pleistocene kangaroo.

    Science.gov (United States)

    Prideaux, Gavin J; Ayliffe, Linda K; DeSantis, Larisa R G; Schubert, Blaine W; Murray, Peter F; Gagan, Michael K; Cerling, Thure E

    2009-07-14

    Kangaroos are the world's most diverse group of herbivorous marsupials. Following late-Miocene intensification of aridity and seasonality, they radiated across Australia, becoming the continent's ecological equivalents of the artiodactyl ungulates elsewhere. Their diversity peaked during the Pleistocene, but by approximately 45,000 years ago, 90% of larger kangaroos were extinct, along with a range of other giant species. Resolving whether climate change or human arrival was the principal extinction cause remains highly contentious. Here we combine craniodental morphology, stable-isotopic, and dental microwear data to reveal that the largest-ever kangaroo, Procoptodon goliah, was a chenopod browse specialist, which may have had a preference for Atriplex (saltbushes), one of a few dicots using the C(4) photosynthetic pathway. Furthermore, oxygen isotope signatures of P. goliah tooth enamel show that it drank more in low-rainfall areas than its grazing contemporaries, similar to modern saltbush feeders. Saltbushes and chenopod shrublands in general are poorly flammable, so landscape burning by humans is unlikely to have caused a reduction in fodder driving the species to extinction. Aridity is discounted as a primary cause because P. goliah evolved in response to increased aridity and disappeared during an interval wetter than many it survived earlier. Hunting by humans, who were also bound to water, may have been a more decisive factor in the extinction of this giant marsupial.

  15. Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas.

    Science.gov (United States)

    Hu, Yibo; Wu, Qi; Ma, Shuai; Ma, Tianxiao; Shan, Lei; Wang, Xiao; Nie, Yonggang; Ning, Zemin; Yan, Li; Xiu, Yunfang; Wei, Fuwen

    2017-01-31

    Phenotypic convergence between distantly related taxa often mirrors adaptation to similar selective pressures and may be driven by genetic convergence. The giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) belong to different families in the order Carnivora, but both have evolved a specialized bamboo diet and adaptive pseudothumb, representing a classic model of convergent evolution. However, the genetic bases of these morphological and physiological convergences remain unknown. Through de novo sequencing the red panda genome and improving the giant panda genome assembly with added data, we identified genomic signatures of convergent evolution. Limb development genes DYNC2H1 and PCNT have undergone adaptive convergence and may be important candidate genes for pseudothumb development. As evolutionary responses to a bamboo diet, adaptive convergence has occurred in genes involved in the digestion and utilization of bamboo nutrients such as essential amino acids, fatty acids, and vitamins. Similarly, the umami taste receptor gene TAS1R1 has been pseudogenized in both pandas. These findings offer insights into genetic convergence mechanisms underlying phenotypic convergence and adaptation to a specialized bamboo diet.

  16. Collagen Sequence Analysis of the Extinct Giant Ground Sloths Lestodon and Megatherium

    Science.gov (United States)

    Buckley, Michael; Fariña, Richard A.; Lawless, Craig; Tambusso, P. Sebastián; Varela, Luciano; Carlini, Alfredo A.; Powell, Jaime E.; Martinez, Jorge G.

    2015-01-01

    For over 200 years, fossils of bizarre extinct creatures have been described from the Americas that have ranged from giant ground sloths to the ‘native’ South American ungulates, groups of mammals that evolved in relative isolation on South America. Ground sloths belong to the South American xenarthrans, a group with modern although morphologically and ecologically very different representatives (anteaters, armadillos and sloths), which has been proposed to be one of the four main eutherian clades. Recently, proteomics analyses of bone collagen have recently been used to yield a molecular phylogeny for a range of mammals including the unusual ‘Malagasy aardvark’ shown to be most closely related to the afrotherian tenrecs, and the south American ungulates supporting their morphological association with condylarths. However, proteomics results generate partial sequence information that could impact upon the phylogenetic placement that has not been appropriately tested. For comparison, this paper examines the phylogenetic potential of proteomics-based sequencing through the analysis of collagen extracted from two extinct giant ground sloths, Lestodon and Megatherium. The ground sloths were placed as sister taxa to extant sloths, but with a closer relationship between Lestodon and the extant sloths than the basal Megatherium. These results highlight that proteomics methods could yield plausible phylogenies that share similarities with other methods, but have the potential to be more useful in fossils beyond the limits of ancient DNA survival. PMID:26540101

  17. How can periodic orbits puzzle out the coexistence of terrestrial planets with giant eccentric ones?

    Science.gov (United States)

    Antoniadou, K. I.; Libert, A.-S.

    2017-09-01

    Hitherto unprecedented detections of exoplanets have been triggered by missions and ground based telescopes. The quest of ``exo-Earths'' has become intriguing and the long-term stability of planetary orbits is a crucial factor for the biosphere to evolve. Planets in mean-motion resonances (MMRs) prompt the investigation of the dynamics in the framework of the three-body problem, where the families of stable periodic orbits constitute the backbone of stability domains in phase space. In this talk, we address the question of the possible coexistence of terrestrial planets with a giant companion on circular or eccentric orbit and explore the extent of the stability regions, when both the eccentricity of the outer giant planet and the semi-major axis of the inner terrestrial one vary, i.e. we investigate both non-resonant and resonant configurations. The families of periodic orbits in the restricted three-body problem are computed for the 3/2, 2/1, 5/2, 3/1, 4/1 and 5/1 MMRs. We then construct maps of dynamical stability (DS-maps) to identify the boundaries of the stability domains where such a coexistence is allowed. Guided by the periodic orbits, we delve into regular motion in phase space and propose the essential values of the orbital elements, in order for such configurations to survive long time spans and hence, for observations to be complemented or revised.

  18. The Pan-Pacific Planet Search. VII. The Most Eccentric Planet Orbiting a Giant Star

    Science.gov (United States)

    Wittenmyer, Robert A.; Jones, M. I.; Horner, Jonathan; Kane, Stephen R.; Marshall, J. P.; Mustill, A. J.; Jenkins, J. S.; Pena Rojas, P. A.; Zhao, Jinglin; Villaver, Eva; Butler, R. P.; Clark, Jake

    2017-12-01

    Radial velocity observations from three instruments reveal the presence of a 4 M Jup planet candidate orbiting the K giant HD 76920. HD 76920b has an orbital eccentricity of 0.856 ± 0.009, making it the most eccentric planet known to orbit an evolved star. There is no indication that HD 76920 has an unseen binary companion, suggesting a scattering event rather than Kozai oscillations as a probable culprit for the observed eccentricity. The candidate planet currently approaches to about four stellar radii from its host star, and is predicted to be engulfed on a ∼100 Myr timescale due to the combined effects of stellar evolution and tidal interactions.

  19. Carbon-rich dust from the asymptotic giant branch to planetary nebulae

    Science.gov (United States)

    Sloan, G. C.

    2017-12-01

    As carbon stars evolve from the asymptotic giant branch to planetary nebulae, the spectrum from the dust around them changes from a mixture dominated by amorphous carbon to one dominated by polycyclic aromatic hydrocarbons (PAHs). Along the way, many other components appear, including SiC and MgS, aliphatic hydrocarbons, the still unidentified 21 μm emission feature, and fullerenes. The evidence from infrared spectral surveys suggests that the dust can form with layered structures, that aliphatics can co-exist with the PAHs in post-AGB objects, and that the appearance of the 21 μm feature is associated with aliphatics. Many uncertainties remain. Perhaps the most important is the composition of the amorphous carbon that dominates dust on the AGB, because different compositions can change the total dust output from carbon stars by nearly an order of magnitude.

  20. Predecessors of the giant 1960 Chile earthquake

    Science.gov (United States)

    Cisternas, M.; Atwater, B.F.; Torrejon, F.; Sawai, Y.; Machuca, G.; Lagos, M.; Eipert, A.; Youlton, C.; Salgado, I.; Kamataki, T.; Shishikura, M.; Rajendran, C.P.; Malik, J.K.; Rizal, Y.; Husni, M.

    2005-01-01

    It is commonly thought that the longer the time since last earthquake, the larger the next earthquake's slip will be. But this logical predictor of earthquake size, unsuccessful for large earthquakes on a strike-slip fault, fails also with the giant 1960 Chile earthquake of magnitude 9.5 (ref. 3). Although the time since the preceding earthquake spanned 123 years (refs 4, 5), the estimated slip in 1960, which occurred on a fault between the Nazca and South American tectonic plates, equalled 250-350 years' worth of the plate motion. Thus the average interval between such giant earthquakes on this fault should span several centuries. Here we present evidence that such long intervals were indeed typical of the last two millennia. We use buried soils and sand layers as records of tectonic subsidence and tsunami inundation at an estuary midway along the 1960 rupture. In these records, the 1960 earthquake ended a recurrence interval that had begun almost four centuries before, with an earthquake documented by Spanish conquistadors in 1575. Two later earthquakes, in 1737 and 1837, produced little if any subsidence or tsunami at the estuary and they therefore probably left the fault partly loaded with accumulated plate motion that the 1960 earthquake then expended. ?? 2005 Nature Publishing Group.

  1. The Fuzziness of Giant Planets’ Cores

    Science.gov (United States)

    Helled, Ravit; Stevenson, David

    2017-05-01

    Giant planets are thought to have cores in their deep interiors, and the division into a heavy-element core and hydrogen-helium envelope is applied in both formation and structure models. We show that the primordial internal structure depends on the planetary growth rate, in particular, the ratio of heavy elements accretion to gas accretion. For a wide range of likely conditions, this ratio is in one-to-one correspondence with the resulting post-accretion profile of heavy elements within the planet. This flux ratio depends sensitively on the assumed solid-surface density in the surrounding nebula. We suggest that giant planets’ cores might not be distinct from the envelope and includes some hydrogen and helium, and the deep interior can have a gradual heavy-element structure. Accordingly, Jupiter’s core may not be well defined. Accurate measurements of Jupiter’s gravitational field by Juno could put constraints on Jupiter’s core mass. However, as we suggest here, the definition of Jupiter’s core is complex, and the core’s physical properties (mass, density) depend on the actual definition of the core and on the planet’s growth history.

  2. The Fuzziness of Giant Planets’ Cores

    Energy Technology Data Exchange (ETDEWEB)

    Helled, Ravit [Institute for Computational Science, University of Zurich, Zurich (Switzerland); Stevenson, David [Division of Geological and Planetary Sciences, Caltech, Pasadena, CA (United States)

    2017-05-01

    Giant planets are thought to have cores in their deep interiors, and the division into a heavy-element core and hydrogen–helium envelope is applied in both formation and structure models. We show that the primordial internal structure depends on the planetary growth rate, in particular, the ratio of heavy elements accretion to gas accretion. For a wide range of likely conditions, this ratio is in one-to-one correspondence with the resulting post-accretion profile of heavy elements within the planet. This flux ratio depends sensitively on the assumed solid-surface density in the surrounding nebula. We suggest that giant planets’ cores might not be distinct from the envelope and includes some hydrogen and helium, and the deep interior can have a gradual heavy-element structure. Accordingly, Jupiter’s core may not be well defined. Accurate measurements of Jupiter’s gravitational field by Juno could put constraints on Jupiter’s core mass. However, as we suggest here, the definition of Jupiter’s core is complex, and the core’s physical properties (mass, density) depend on the actual definition of the core and on the planet’s growth history.

  3. Predecessors of the giant 1960 Chile earthquake

    Science.gov (United States)

    Cisternas, Marco; Atwater, Brian F.; Torrejón, Fernando; Sawai, Yuki; Machuca, Gonzalo; Lagos, Marcelo; Eipert, Annaliese; Youlton, Cristián; Salgado, Ignacio; Kamataki, Takanobu; Shishikura, Masanobu; Rajendran, C. P.; Malik, Javed K.; Rizal, Yan; Husni, Muhammad

    2005-09-01

    It is commonly thought that the longer the time since last earthquake, the larger the next earthquake's slip will be. But this logical predictor of earthquake size, unsuccessful for large earthquakes on a strike-slip fault, fails also with the giant 1960 Chile earthquake of magnitude 9.5 (ref. 3). Although the time since the preceding earthquake spanned 123years (refs 4, 5), the estimated slip in 1960, which occurred on a fault between the Nazca and South American tectonic plates, equalled 250-350years' worth of the plate motion. Thus the average interval between such giant earthquakes on this fault should span several centuries. Here we present evidence that such long intervals were indeed typical of the last two millennia. We use buried soils and sand layers as records of tectonic subsidence and tsunami inundation at an estuary midway along the 1960 rupture. In these records, the 1960 earthquake ended a recurrence interval that had begun almost four centuries before, with an earthquake documented by Spanish conquistadors in 1575. Two later earthquakes, in 1737 and 1837, produced little if any subsidence or tsunami at the estuary and they therefore probably left the fault partly loaded with accumulated plate motion that the 1960 earthquake then expended.

  4. Literature review of giant gartersnake (Thamnophis gigas) biology and conservation

    Science.gov (United States)

    Halstead, Brian J.; Wylie, Glenn D.; Casazza, Michael L.

    2015-08-03

    This report reviews the available literature on giant gartersnakes (Thamnophis gigas) to compile existing information on this species and identify knowledge gaps that, if addressed, would help to inform conservation efforts for giant gartersnakes.  Giant gartersnakes comprise a species of semi-aquatic snake precinctive to wetlands in the Central Valley of California.  The diversion of surface water and conversion of wetlands to agricultural and other land uses resulted in the loss of more than 90 percent of natural giant gartersnake habitats.  Because of this habitat loss, giant gartersnakes are now listed by the United States and California Endangered Species Acts as Threatened.  Most extant populations occur in the rice-growing regions of the Sacramento Valley, which comprises the northern portion of the giant gartersnake’s former range.  The huge demand for water in California for agriculture, industry, recreation, and other human consumption, combined with periodic severe drought, places remaining giant gartersnake habitats at increased risk of degradation and loss.  This literature review summarizes the available information on giant gartersnake distribution, habitat relations, behavior, demography, and other aspects of its biology relevant to conservation.  This information is then compiled into a graphical conceptual model that indicates the importance of different aspects of giant gartersnake biology for maintaining positive population growth, and identifies those areas for which important information relevant for conservation is lacking.  Directing research efforts toward these aspects of giant gartersnake ecology will likely result in improvements to conserving this unique species while meeting the high demands for water in California.

  5. The evolving energy budget of accretionary wedges

    Science.gov (United States)

    McBeck, Jessica; Cooke, Michele; Maillot, Bertrand; Souloumiac, Pauline

    2017-04-01

    The energy budget of evolving accretionary systems reveals how deformational processes partition energy as faults slip, topography uplifts, and layer-parallel shortening produces distributed off-fault deformation. The energy budget provides a quantitative framework for evaluating the energetic contribution or consumption of diverse deformation mechanisms. We investigate energy partitioning in evolving accretionary prisms by synthesizing data from physical sand accretion experiments and numerical accretion simulations. We incorporate incremental strain fields and cumulative force measurements from two suites of experiments to design numerical simulations that represent accretionary wedges with stronger and weaker detachment faults. One suite of the physical experiments includes a basal glass bead layer and the other does not. Two physical experiments within each suite implement different boundary conditions (stable base versus moving base configuration). Synthesizing observations from the differing base configurations reduces the influence of sidewall friction because the force vector produced by sidewall friction points in opposite directions depending on whether the base is fixed or moving. With the numerical simulations, we calculate the energy budget at two stages of accretion: at the maximum force preceding the development of the first thrust pair, and at the minimum force following the development of the pair. To identify the appropriate combination of material and fault properties to apply in the simulations, we systematically vary the Young's modulus and the fault static and dynamic friction coefficients in numerical accretion simulations, and identify the set of parameters that minimizes the misfit between the normal force measured on the physical backwall and the numerically simulated force. Following this derivation of the appropriate material and fault properties, we calculate the components of the work budget in the numerical simulations and in the

  6. Enormous Li Enhancement Preceding Red Giant Phases in Low-mass Stars in the Milky Way Halo

    Science.gov (United States)

    Li, Haining; Aoki, Wako; Matsuno, Tadafumi; Bharat Kumar, Yerra; Shi, Jianrong; Suda, Takuma; Zhao, Gang

    2018-01-01

    Li abundances in the bulk of low-mass metal-poor stars are well reproduced by stellar evolution models adopting a constant initial abundance. However, a small number of stars have exceptionally high Li abundances, for which no convincing models have been established. We report on the discovery of 12 very metal-poor stars that have large excesses of Li, including an object having more than 100 times higher Li abundance than the values found in usual objects, which is the largest excess in metal-poor stars known to date. The sample is distributed over a wide range of evolutionary stages, including five unevolved stars, showing no clear abundance anomaly in other elements. The results indicate the existence of an efficient process to enrich Li in a small fraction of low-mass stars at the main-sequence or subgiant phase. The wide distribution of Li-rich stars along the red giant branch could be explained by the dilution of surface Li by mixing that occurs when the stars evolve into red giants. Our study narrows down the problem to be solved in order to understand the origins of Li excess found in low-mass stars, suggesting the presence of an unknown process that affects the surface abundances preceding red giant phases. This work is based on data collected at the Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

  7. The World is Spinning: Constraining the Origin of Supermassive Gas Giant Planets at Wide Separations Using Planetary Spin

    Science.gov (United States)

    Bryan, Marta; Knutson, Heather; Batygin, Konstantin; Benneke, Björn; Bowler, Brendan

    2017-01-01

    Planetary spin can inform our understanding of planet accretion histories, which determine final masses and atmospheric compositions, as well as the formation of moons and rings. At present, the physics behind how gas giant planets spin up is still very poorly understood. We know that when giant planets form, they accrete material and angular momentum via a circumplanetary disk, causing the planet to spin up. In order to prevent planet spins from reaching break-up velocity, some mechanism must regulate these spins. However, there is currently no well-formulated picture for how planet spins evolve. This is in part due to the fact that there are very few measurements of giant planet spin rates currently available. Outside the solar system, to date there has only been one published spin measurement of a directly imaged planet, beta Pic b. We use Keck/NIRSPEC to measure spin rates for a sample of bound and free-floating directly imaged planetary mass objects, providing a first look at the distribution of spin rates for these objects.

  8. Eye retraction in the giant guitarfish, Rhynchobatus djiddensis (Elasmobranchii: Batoidea): a novel mechanism for eye protection in batoid fishes.

    Science.gov (United States)

    Tomita, Taketeru; Murakumo, Kiyomi; Miyamoto, Kei; Sato, Keiichi; Oka, Shin-ichiro; Kamisako, Haruka; Toda, Minoru

    2016-02-01

    Eye retraction behavior has evolved independently in some vertebrate linages such as mudskippers (fish), frogs and salamanders (amphibians), and cetaceans (mammals). In this paper, we report the eye retraction behavior of the giant guitarfish (Rhynchobatus djiddensis) for the first time, and discuss its mechanism and function. The eye retraction distance was nearly the same as the diameter of the eyeball itself, indicating that eye retraction in the giant guitarfish is probably one of the largest among vertebrates. Eye retraction is achieved by unique arrangement of the eye muscle: one of the anterior eye muscles (the obliquus inferior) is directed ventrally from the eyeball and attaches to the ventral surface of the neurocranium. Due to such muscle arrangement, the obliquus inferior can pull the eyeball ventrally. This mechanism was also confirmed by electrical stimulation of the obliquus inferior. The eye retraction ability of the giant guitarfish likely represents a novel eye protection behavior of elasmobranch fishes. Copyright © 2015 Elsevier GmbH. All rights reserved.

  9. Giant viruses coexisted with the cellular ancestors and represent a distinct supergroup along with superkingdoms Archaea, Bacteria and Eukarya

    Directory of Open Access Journals (Sweden)

    Nasir Arshan

    2012-08-01

    Full Text Available Abstract Background The discovery of giant viruses with genome and physical size comparable to cellular organisms, remnants of protein translation machinery and virus-specific parasites (virophages have raised intriguing questions about their origin. Evidence advocates for their inclusion into global phylogenomic studies and their consideration as a distinct and ancient form of life. Results Here we reconstruct phylogenies describing the evolution of proteomes and protein domain structures of cellular organisms and double-stranded DNA viruses with medium-to-very-large proteomes (giant viruses. Trees of proteomes define viruses as a ‘fourth supergroup’ along with superkingdoms Archaea, Bacteria, and Eukarya. Trees of domains indicate they have evolved via massive and primordial reductive evolutionary processes. The distribution of domain structures suggests giant viruses harbor a significant number of protein domains including those with no cellular representation. The genomic and structural diversity embedded in the viral proteomes is comparable to the cellular proteomes of organisms with parasitic lifestyles. Since viral domains are widespread among cellular species, we propose that viruses mediate gene transfer between cells and crucially enhance biodiversity. Conclusions Results call for a change in the way viruses are perceived. They likely represent a distinct form of life that either predated or coexisted with the last universal common ancestor (LUCA and constitute a very crucial part of our planet’s biosphere.

  10. On the Critical Role of Divergent Selection in Evolvability

    Directory of Open Access Journals (Sweden)

    Joel Lehman

    2016-08-01

    Full Text Available An ambitious goal in evolutionary robotics is to evolve increasingly complex robotic behaviors with minimal human design effort. Reaching this goal requires evolutionary algorithms that can unlock from genetic encodings their latent potential for evolvability. One issue clouding this goal is conceptual confusion about evolvability, which often obscures the aspects of evolvability that are important or desirable. The danger from such confusion is that it may establish unrealistic goals for evolvability that prove unproductive in practice. An important issue separate from conceptual confusion is the common misalignment between selection and evolvability in evolutionary robotics. While more expressive encodings can represent higher-level adaptations (e.g. sexual reproduction or developmental systems that increase long-term evolutionary potential (i.e. evolvability, realizing such potential requires gradients of fitness and evolvability to align. In other words, selection is often a critical factor limiting increasing evolvability. Thus, drawing from a series of recent papers, this article seeks to both (1 clarify and focus the ways in which the term evolvability is used within artificial evolution, and (2 argue for the importance of one type of selection, i.e. divergent selection, for enabling evolvability. The main argument is that there is a fundamental connection between divergent selection and evolvability (on both the individual and population level that does not hold for typical goal-oriented selection. The conclusion is that selection pressure plays a critical role in realizing the potential for evolvability, and that divergent selection in particular provides a principled mechanism for encouraging evolvability in artificial evolution.

  11. How does cognition evolve? Phylogenetic comparative psychology

    Science.gov (United States)

    Matthews, Luke J.; Hare, Brian A.; Nunn, Charles L.; Anderson, Rindy C.; Aureli, Filippo; Brannon, Elizabeth M.; Call, Josep; Drea, Christine M.; Emery, Nathan J.; Haun, Daniel B. M.; Herrmann, Esther; Jacobs, Lucia F.; Platt, Michael L.; Rosati, Alexandra G.; Sandel, Aaron A.; Schroepfer, Kara K.; Seed, Amanda M.; Tan, Jingzhi; van Schaik, Carel P.; Wobber, Victoria

    2014-01-01

    Now more than ever animal studies have the potential to test hypotheses regarding how cognition evolves. Comparative psychologists have developed new techniques to probe the cognitive mechanisms underlying animal behavior, and they have become increasingly skillful at adapting methodologies to test multiple species. Meanwhile, evolutionary biologists have generated quantitative approaches to investigate the phylogenetic distribution and function of phenotypic traits, including cognition. In particular, phylogenetic methods can quantitatively (1) test whether specific cognitive abilities are correlated with life history (e.g., lifespan), morphology (e.g., brain size), or socio-ecological variables (e.g., social system), (2) measure how strongly phylogenetic relatedness predicts the distribution of cognitive skills across species, and (3) estimate the ancestral state of a given cognitive trait using measures of cognitive performance from extant species. Phylogenetic methods can also be used to guide the selection of species comparisons that offer the strongest tests of a priori predictions of cognitive evolutionary hypotheses (i.e., phylogenetic targeting). Here, we explain how an integration of comparative psychology and evolutionary biology will answer a host of questions regarding the phylogenetic distribution and history of cognitive traits, as well as the evolutionary processes that drove their evolution. PMID:21927850

  12. Approximating centrality in evolving graphs: toward sublinearity

    Science.gov (United States)

    Priest, Benjamin W.; Cybenko, George

    2017-05-01

    The identification of important nodes is a ubiquitous problem in the analysis of social networks. Centrality indices (such as degree centrality, closeness centrality, betweenness centrality, PageRank, and others) are used across many domains to accomplish this task. However, the computation of such indices is expensive on large graphs. Moreover, evolving graphs are becoming increasingly important in many applications. It is therefore desirable to develop on-line algorithms that can approximate centrality measures using memory sublinear in the size of the graph. We discuss the challenges facing the semi-streaming computation of many centrality indices. In particular, we apply recent advances in the streaming and sketching literature to provide a preliminary streaming approximation algorithm for degree centrality utilizing CountSketch and a multi-pass semi-streaming approximation algorithm for closeness centrality leveraging a spanner obtained through iteratively sketching the vertex-edge adjacency matrix. We also discuss possible ways forward for approximating betweenness centrality, as well as spectral measures of centrality. We provide a preliminary result using sketched low-rank approximations to approximate the output of the HITS algorithm.

  13. How does cognition evolve? Phylogenetic comparative psychology.

    Science.gov (United States)

    MacLean, Evan L; Matthews, Luke J; Hare, Brian A; Nunn, Charles L; Anderson, Rindy C; Aureli, Filippo; Brannon, Elizabeth M; Call, Josep; Drea, Christine M; Emery, Nathan J; Haun, Daniel B M; Herrmann, Esther; Jacobs, Lucia F; Platt, Michael L; Rosati, Alexandra G; Sandel, Aaron A; Schroepfer, Kara K; Seed, Amanda M; Tan, Jingzhi; van Schaik, Carel P; Wobber, Victoria

    2012-03-01

    Now more than ever animal studies have the potential to test hypotheses regarding how cognition evolves. Comparative psychologists have developed new techniques to probe the cognitive mechanisms underlying animal behavior, and they have become increasingly skillful at adapting methodologies to test multiple species. Meanwhile, evolutionary biologists have generated quantitative approaches to investigate the phylogenetic distribution and function of phenotypic traits, including cognition. In particular, phylogenetic methods can quantitatively (1) test whether specific cognitive abilities are correlated with life history (e.g., lifespan), morphology (e.g., brain size), or socio-ecological variables (e.g., social system), (2) measure how strongly phylogenetic relatedness predicts the distribution of cognitive skills across species, and (3) estimate the ancestral state of a given cognitive trait using measures of cognitive performance from extant species. Phylogenetic methods can also be used to guide the selection of species comparisons that offer the strongest tests of a priori predictions of cognitive evolutionary hypotheses (i.e., phylogenetic targeting). Here, we explain how an integration of comparative psychology and evolutionary biology will answer a host of questions regarding the phylogenetic distribution and history of cognitive traits, as well as the evolutionary processes that drove their evolution.

  14. On the Discovery of Evolving Truth.

    Science.gov (United States)

    Li, Yaliang; Li, Qi; Gao, Jing; Su, Lu; Zhao, Bo; Fan, Wei; Han, Jiawei

    2015-08-01

    In the era of big data, information regarding the same objects can be collected from increasingly more sources. Unfortunately, there usually exist conflicts among the information coming from different sources. To tackle this challenge, truth discovery, i.e., to integrate multi-source noisy information by estimating the reliability of each source, has emerged as a hot topic. In many real world applications, however, the information may come sequentially, and as a consequence, the truth of objects as well as the reliability of sources may be dynamically evolving. Existing truth discovery methods, unfortunately, cannot handle such scenarios. To address this problem, we investigate the temporal relations among both object truths and source reliability, and propose an incremental truth discovery framework that can dynamically update object truths and source weights upon the arrival of new data. Theoretical analysis is provided to show that the proposed method is guaranteed to converge at a fast rate. The experiments on three real world applications and a set of synthetic data demonstrate the advantages of the proposed method over state-of-the-art truth discovery methods.

  15. Sexual regret: evidence for evolved sex differences.

    Science.gov (United States)

    Galperin, Andrew; Haselton, Martie G; Frederick, David A; Poore, Joshua; von Hippel, William; Buss, David M; Gonzaga, Gian C

    2013-10-01

    Regret and anticipated regret enhance decision quality by helping people avoid making and repeating mistakes. Some of people's most intense regrets concern sexual decisions. We hypothesized evolved sex differences in women's and men's experiences of sexual regret. Because of women's higher obligatory costs of reproduction throughout evolutionary history, we hypothesized that sexual actions, particularly those involving casual sex, would be regretted more intensely by women than by men. In contrast, because missed sexual opportunities historically carried higher reproductive fitness costs for men than for women, we hypothesized that poorly chosen sexual inactions would be regretted more by men than by women. Across three studies (Ns = 200, 395, and 24,230), we tested these hypotheses using free responses, written scenarios, detailed checklists, and Internet sampling to achieve participant diversity, including diversity in sexual orientation. Across all data sources, results supported predicted psychological sex differences and these differences were localized in casual sex contexts. These findings are consistent with the notion that the psychology of sexual regret was shaped by recurrent sex differences in selection pressures operating over deep time.

  16. Extracting evolving pathologies via spectral clustering.

    Science.gov (United States)

    Bernardis, Elena; Pohl, Kilian M; Davatzikos, Christos

    2013-01-01

    A bottleneck in the analysis of longitudinal MR scans with white matter brain lesions is the temporally consistent segmentation of the pathology. We identify pathologies in 3D+t(ime) within a spectral graph clustering framework. Our clustering approach simultaneously segments and tracks the evolving lesions by identifying characteristic image patterns at each time-point and voxel correspondences across time-points. For each 3D image, our method constructs a graph where weights between nodes capture the likeliness of two voxels belonging to the same region. Based on these weights, we then establish rough correspondences between graph nodes at different time-points along estimated pathology evolution directions. We combine the graphs by aligning the weights to a reference time-point, thus integrating temporal information across the 3D images, and formulate the 3D+t segmentation problem as a binary partitioning of this graph. The resulting segmentation is very robust to local intensity fluctuations and yields better results than segmentations generated for each time-point.

  17. Functional Topology of Evolving Urban Drainage Networks

    Science.gov (United States)

    Yang, Soohyun; Paik, Kyungrock; McGrath, Gavan S.; Urich, Christian; Krueger, Elisabeth; Kumar, Praveen; Rao, P. Suresh C.

    2017-11-01

    We investigated the scaling and topology of engineered urban drainage networks (UDNs) in two cities, and further examined UDN evolution over decades. UDN scaling was analyzed using two power law scaling characteristics widely employed for river networks: (1) Hack's law of length (L)-area (A) [L∝Ah] and (2) exceedance probability distribution of upstream contributing area (δ) [P>(A≥δ>)˜aδ-ɛ]. For the smallest UDNs ((A≥δ>) plots for river networks are abruptly truncated, those for UDNs display exponential tempering [P>(A≥δ>)=aδ-ɛexp⁡>(-cδ>)]. The tempering parameter c decreases as the UDNs grow, implying that the distribution evolves in time to resemble those for river networks. However, the power law exponent ɛ for large UDNs tends to be greater than the range reported for river networks. Differences in generative processes and engineering design constraints contribute to observed differences in the evolution of UDNs and river networks, including subnet heterogeneity and nonrandom branching.

  18. The Evolving Classification of Pulmonary Hypertension.

    Science.gov (United States)

    Foshat, Michelle; Boroumand, Nahal

    2017-05-01

    - An explosion of information on pulmonary hypertension has occurred during the past few decades. The perception of this disease has shifted from purely clinical to incorporate new knowledge of the underlying pathology. This transfer has occurred in light of advancements in pathophysiology, histology, and molecular medical diagnostics. - To update readers about the evolving understanding of the etiology and pathogenesis of pulmonary hypertension and to demonstrate how pathology has shaped the current classification. - Information presented at the 5 World Symposia on pulmonary hypertension held since 1973, with the last meeting occurring in 2013, was used in this review. - Pulmonary hypertension represents a heterogeneous group of disorders that are differentiated based on differences in clinical, hemodynamic, and histopathologic features. Early concepts of pulmonary hypertension were largely influenced by pharmacotherapy, hemodynamic function, and clinical presentation of the disease. The initial nomenclature for pulmonary hypertension segregated the clinical classifications from pathologic subtypes. Major restructuring of this disease classification occurred between the first and second symposia, which was the first to unite clinical and pathologic information in the categorization scheme. Additional changes were introduced in subsequent meetings, particularly between the third and fourth World Symposia meetings, when additional pathophysiologic information was gained. Discoveries in molecular diagnostics significantly progressed the understanding of idiopathic pulmonary arterial hypertension. Continued advancements in imaging modalities, mechanistic pathogenicity, and molecular biomarkers will enable physicians to define pulmonary hypertension phenotypes based on the pathobiology and allow for treatment customization.

  19. Evolving application of biomimetic nanostructured hydroxyapatite

    Directory of Open Access Journals (Sweden)

    Norberto Roveri

    2010-11-01

    Full Text Available Norberto Roveri, Michele IafiscoLaboratory of Environmental and Biological Structural Chemistry (LEBSC, Dipartimento di Chimica ‘G. Ciamician’, Alma Mater Studiorum, Università di Bologna, Bologna, ItalyAbstract: By mimicking Nature, we can design and synthesize inorganic smart materials that are reactive to biological tissues. These smart materials can be utilized to design innovative third-generation biomaterials, which are able to not only optimize their interaction with biological tissues and environment, but also mimic biogenic materials in their functionalities. The biomedical applications involve increasing the biomimetic levels from chemical composition, structural organization, morphology, mechanical behavior, nanostructure, and bulk and surface chemical–physical properties until the surface becomes bioreactive and stimulates cellular materials. The chemical–physical characteristics of biogenic hydroxyapatites from bone and tooth have been described, in order to point out the elective sides, which are important to reproduce the design of a new biomimetic synthetic hydroxyapatite. This review outlines the evolving applications of biomimetic synthetic calcium phosphates, details the main characteristics of bone and tooth, where the calcium phosphates are present, and discusses the chemical–physical characteristics of biomimetic calcium phosphates, methods of synthesizing them, and some of their biomedical applications.Keywords: hydroxyapatite, nanocrystals, biomimetism, biomaterials, drug delivery, remineralization

  20. Evolving application of biomimetic nanostructured hydroxyapatite.

    Science.gov (United States)

    Roveri, Norberto; Iafisco, Michele

    2010-11-09

    By mimicking Nature, we can design and synthesize inorganic smart materials that are reactive to biological tissues. These smart materials can be utilized to design innovative third-generation biomaterials, which are able to not only optimize their interaction with biological tissues and environment, but also mimic biogenic materials in their functionalities. The biomedical applications involve increasing the biomimetic levels from chemical composition, structural organization, morphology, mechanical behavior, nanostructure, and bulk and surface chemical-physical properties until the surface becomes bioreactive and stimulates cellular materials. The chemical-physical characteristics of biogenic hydroxyapatites from bone and tooth have been described, in order to point out the elective sides, which are important to reproduce the design of a new biomimetic synthetic hydroxyapatite. This review outlines the evolving applications of biomimetic synthetic calcium phosphates, details the main characteristics of bone and tooth, where the calcium phosphates are present, and discusses the chemical-physical characteristics of biomimetic calcium phosphates, methods of synthesizing them, and some of their biomedical applications.

  1. Epidemic spreading on evolving signed networks

    Science.gov (United States)

    Saeedian, M.; Azimi-Tafreshi, N.; Jafari, G. R.; Kertesz, J.

    2017-02-01

    Most studies of disease spreading consider the underlying social network as obtained without the contagion, though epidemic influences people's willingness to contact others: A "friendly" contact may be turned to "unfriendly" to avoid infection. We study the susceptible-infected disease-spreading model on signed networks, in which each edge is associated with a positive or negative sign representing the friendly or unfriendly relation between its end nodes. In a signed network, according to Heider's theory, edge signs evolve such that finally a state of structural balance is achieved, corresponding to no frustration in physics terms. However, the danger of infection affects the evolution of its edge signs. To describe the coupled problem of the sign evolution and disease spreading, we generalize the notion of structural balance by taking into account the state of the nodes. We introduce an energy function and carry out Monte Carlo simulations on complete networks to test the energy landscape, where we find local minima corresponding to the so-called jammed states. We study the effect of the ratio of initial friendly to unfriendly connections on the propagation of disease. The steady state can be balanced or a jammed state such that a coexistence occurs between susceptible and infected nodes in the system.

  2. UKAEA'S evolving contract philosophy

    Energy Technology Data Exchange (ETDEWEB)

    Nicol, R. D. [UK Atomic Energy Authority, UKAEA, Harwell, Oxfordshire (United Kingdom)

    2003-07-01

    The United Kingdom Atomic Energy Authority (UKAEA) has gone through fundamental change over the last ten years. At the heart of this change has been UKAEA's relationship with the contracting and supply market. This paper describes the way in which UKAEA actively developed the market to support the decommissioning programme, and how the approach to contracting has evolved as external pressures and demands have changed. UKAEA's pro-active approach to industry has greatly assisted the development of a healthy, competitive market for services supporting decommissioning in the UK. There have been difficult changes and many challenges along the way, and some retrenchment was necessary to meet regulatory requirements. Nevertheless, UKAEA has sustained a high level of competition - now measured in terms of competed spend as a proportion of competable spend - with annual out-turns consistently over 80%. The prime responsibility for market development will pass to the new Nuclear Decommissioning Authority (NDA) in 2005, as the owner, on behalf of the Government, of the UK's civil nuclear liabilities. The preparatory work for the NDA indicates that the principles established by UKAEA will be carried forward. (author)

  3. An evolving model of online bipartite networks

    Science.gov (United States)

    Zhang, Chu-Xu; Zhang, Zi-Ke; Liu, Chuang

    2013-12-01

    Understanding the structure and evolution of online bipartite networks is a significant task since they play a crucial role in various e-commerce services nowadays. Recently, various attempts have been tried to propose different models, resulting in either power-law or exponential degree distributions. However, many empirical results show that the user degree distribution actually follows a shifted power-law distribution, the so-called Mandelbrot’s law, which cannot be fully described by previous models. In this paper, we propose an evolving model, considering two different user behaviors: random and preferential attachment. Extensive empirical results on two real bipartite networks, Delicious and CiteULike, show that the theoretical model can well characterize the structure of real networks for both user and object degree distributions. In addition, we introduce a structural parameter p, to demonstrate that the hybrid user behavior leads to the shifted power-law degree distribution, and the region of power-law tail will increase with the increment of p. The proposed model might shed some lights in understanding the underlying laws governing the structure of real online bipartite networks.

  4. Cyanogen in NGC 1851 Red Giant Branch and Asymptotic Giant Branch Stars: Quadrimodal Distributions

    DEFF Research Database (Denmark)

    Campbell, S. W.; Yong, D.; Wylie-de Boer, E. C.

    2012-01-01

    The Galactic globular cluster NGC 1851 has raised much interest since Hubble Space Telescope photometry revealed that it hosts a double subgiant branch. Here we report on our homogeneous study into the cyanogen (CN) band strengths in the red giant branch (RGB) population (17 stars) and asymptotic...... giant branch (AGB) population (21 stars) using AAOmega/2dF spectra with R ~ 3000. We discover that NGC 1851 hosts a quadrimodal distribution of CN band strengths in its RGB and AGB populations. This result supports the merger formation scenario proposed for this cluster, such that the CN quadrimodality...... found that the four CN peaks may be paired—the two CN-weaker populations being associated with low Ba and the two CN-stronger populations with high Ba. If true, then s-process abundances would be a good diagnostic for disentangling the two original clusters in the merger scenario. More observations...

  5. Role of nature reserves in giant panda protection.

    Science.gov (United States)

    Kang, Dongwei; Li, Junqing

    2017-11-28

    Giant panda (Ailuropoda melanoleuca) is a flagship species in nature conservation of the world; to protect this species, 67 nature reserves have been established in China. To evaluate the protection effect of giant panda nature reserves, we analyzed the variation of giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province based on the national survey data released by State Forestry Administration and Sichuan Forestry Department. Results showed that from the third national survey to the fourth, giant panda number and habitat area of 23 giant panda nature reserves of Sichuan province failed to realize the significant increase. Furthermore, we found that the total population growth rate of 23 nature reserves in the last 12 years was lower than those of the province total of Sichuan and the national total of China, and the total habitat area of the 23 nature reserves was decreasing in the last 12 years, but the province total and national total were all increasing. We propose that giant panda protection should pay more attention to how to improve the protective effects of nature reserves.

  6. Globally intertwined evolutionary history of giant barrel sponges

    Science.gov (United States)

    Swierts, Thomas; Peijnenburg, Katja T. C. A.; de Leeuw, Christiaan A.; Breeuwer, Johannes A. J.; Cleary, Daniel F. R.; de Voogd, Nicole J.

    2017-09-01

    Three species of giant barrel sponge are currently recognized in two distinct geographic regions, the tropical Atlantic and the Indo-Pacific. In this study, we used molecular techniques to study populations of giant barrel sponges across the globe and assessed whether the genetic structure of these populations agreed with current taxonomic consensus or, in contrast, whether there was evidence of cryptic species. Using molecular data, we assessed whether giant barrel sponges in each oceanic realm represented separate monophyletic lineages. Giant barrel sponges from 17 coral reef systems across the globe were sequenced for mitochondrial (partial CO1 and ATP6 genes) and nuclear (ATPsβ intron) DNA markers. In total, we obtained 395 combined sequences of the mitochondrial CO1 and ATP6 markers, which resulted in 17 different haplotypes. We compared a phylogenetic tree constructed from 285 alleles of the nuclear intron ATPsβ to the 17 mitochondrial haplotypes. Congruent patterns between mitochondrial and nuclear gene trees of giant barrel sponges provided evidence for the existence of multiple reproductively isolated species, particularly where they occurred in sympatry. The species complexes in the tropical Atlantic and the Indo-Pacific, however, do not form separate monophyletic lineages. This rules out the scenario that one species of giant barrel sponge developed into separate species complexes following geographic separation and instead suggests that multiple species of giant barrel sponges already existed prior to the physical separation of the Indo-Pacific and tropical Atlantic.

  7. Quantum mechanics in an evolving Hilbert space

    Science.gov (United States)

    Artacho, Emilio; O'Regan, David D.

    2017-03-01

    Many basis sets for electronic structure calculations evolve with varying external parameters, such as moving atoms in dynamic simulations, giving rise to extra derivative terms in the dynamical equations. Here we revisit these derivatives in the context of differential geometry, thereby obtaining a more transparent formalization, and a geometrical perspective for better understanding the resulting equations. The effect of the evolution of the basis set within the spanned Hilbert space separates explicitly from the effect of the turning of the space itself when moving in parameter space, as the tangent space turns when moving in a curved space. New insights are obtained using familiar concepts in that context such as the Riemann curvature. The differential geometry is not strictly that for curved spaces as in general relativity, a more adequate mathematical framework being provided by fiber bundles. The language used here, however, will be restricted to tensors and basic quantum mechanics. The local gauge implied by a smoothly varying basis set readily connects with Berry's formalism for geometric phases. Generalized expressions for the Berry connection and curvature are obtained for a parameter-dependent occupied Hilbert space spanned by nonorthogonal Wannier functions. The formalism is applicable to basis sets made of atomic-like orbitals and also more adaptative moving basis functions (such as in methods using Wannier functions as intermediate or support bases), but should also apply to other situations in which nonorthogonal functions or related projectors should arise. The formalism is applied to the time-dependent quantum evolution of electrons for moving atoms. The geometric insights provided here allow us to propose new finite-difference time integrators, and also better understand those already proposed.

  8. The evolving role of tiotropium in asthma

    Directory of Open Access Journals (Sweden)

    McIvor ER

    2017-08-01

    Full Text Available Emma R McIvor,1 R Andrew McIvor2 1Queen’s University, Belfast, UK; 2Department of Medicine, McMaster University, Firestone Institute for Respiratory Health, Hamilton, Ontario, Canada Abstract: Tiotropium is a long-acting muscarinic antagonist (LAMA that exerts its bronchodilatory effect by blocking endogenous acetylcholine receptors in the airways. Its safety and efficacy are well established for the treatment of COPD, and it is now being recognized for its role in improving lung function and control in asthma. This review discusses the evolving role of tiotropium delivered by the Respimat® in patients across the range of asthma severities and ages, and provides an overview of safety and efficacy data. Tiotropium is the only LAMA currently approved for the treatment of asthma, and evidence from a large-scale clinical trial program, including several Phase III studies in adults, has demonstrated that tiotropium improves lung function and asthma control, with a safety profile comparable with that of placebo. Clinical trials in adolescent patients (aged 12–17 years have also shown improvements in lung function and trends toward improved asthma control. Of note, the efficacy and safety profiles are consistent regardless of baseline characteristics and phenotype. Given the large and growing body of evidence, it is likely that as clinical experience with tiotropium increases, this treatment may possibly emerge as the key choice for add-on therapy to inhaled corticosteroids/long-acting β2-agonists, and in patients who do not tolerate long-acting bronchodilators or other medications, in the future. Keywords: tiotropium, anticholinergics, asthma, efficacy

  9. Emergent spacetime in stochastically evolving dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Afshordi, Niayesh [Perimeter Institute for Theoretical Physics, 31 Caroline St. N., Waterloo, ON, N2L 2Y5 (Canada); Department of Physics and Astronomy, University of Waterloo, Waterloo, ON, N2L 3G1 (Canada); HEPCOS, Department of Physics, SUNY at Buffalo, Buffalo, NY 14260-1500 (United States); Stojkovic, Dejan, E-mail: ds77@buffalo.edu [Perimeter Institute for Theoretical Physics, 31 Caroline St. N., Waterloo, ON, N2L 2Y5 (Canada); HEPCOS, Department of Physics, SUNY at Buffalo, Buffalo, NY 14260-1500 (United States)

    2014-12-12

    Changing the dimensionality of the space–time at the smallest and largest distances has manifold theoretical advantages. If the space is lower dimensional in the high energy regime, then there are no ultraviolet divergencies in field theories, it is possible to quantize gravity, and the theory of matter plus gravity is free of divergencies or renormalizable. If the space is higher dimensional at cosmological scales, then some cosmological problems (including the cosmological constant problem) can be attacked from a completely new perspective. In this paper, we construct an explicit model of “evolving dimensions” in which the dimensions open up as the temperature of the universe drops. We adopt the string theory framework in which the dimensions are fields that live on the string worldsheet, and add temperature dependent mass terms for them. At the Big Bang, all the dimensions are very heavy and are not excited. As the universe cools down, dimensions open up one by one. Thus, the dimensionality of the space we live in depends on the energy or temperature that we are probing. In particular, we provide a kinematic Brandenberger–Vafa argument for how a discrete causal set, and eventually a continuum (3+1)-dim spacetime along with Einstein gravity emerges in the Infrared from the worldsheet action. The (3+1)-dim Planck mass and the string scale become directly related, without any compactification. Amongst other predictions, we argue that LHC might be blind to new physics even if it comes at the TeV scale. In contrast, cosmic ray experiments, especially those that can register the very beginning of the shower, and collisions with high multiplicity and density of particles, might be sensitive to the dimensional cross-over.

  10. Emergent spacetime in stochastically evolving dimensions

    Science.gov (United States)

    Afshordi, Niayesh; Stojkovic, Dejan

    2014-12-01

    Changing the dimensionality of the space-time at the smallest and largest distances has manifold theoretical advantages. If the space is lower dimensional in the high energy regime, then there are no ultraviolet divergencies in field theories, it is possible to quantize gravity, and the theory of matter plus gravity is free of divergencies or renormalizable. If the space is higher dimensional at cosmological scales, then some cosmological problems (including the cosmological constant problem) can be attacked from a completely new perspective. In this paper, we construct an explicit model of ;evolving dimensions; in which the dimensions open up as the temperature of the universe drops. We adopt the string theory framework in which the dimensions are fields that live on the string worldsheet, and add temperature dependent mass terms for them. At the Big Bang, all the dimensions are very heavy and are not excited. As the universe cools down, dimensions open up one by one. Thus, the dimensionality of the space we live in depends on the energy or temperature that we are probing. In particular, we provide a kinematic Brandenberger-Vafa argument for how a discrete causal set, and eventually a continuum (3 + 1)-dim spacetime along with Einstein gravity emerges in the Infrared from the worldsheet action. The (3 + 1)-dim Planck mass and the string scale become directly related, without any compactification. Amongst other predictions, we argue that LHC might be blind to new physics even if it comes at the TeV scale. In contrast, cosmic ray experiments, especially those that can register the very beginning of the shower, and collisions with high multiplicity and density of particles, might be sensitive to the dimensional cross-over.

  11. Emergent spacetime in stochastically evolving dimensions

    Directory of Open Access Journals (Sweden)

    Niayesh Afshordi

    2014-12-01

    Full Text Available Changing the dimensionality of the space–time at the smallest and largest distances has manifold theoretical advantages. If the space is lower dimensional in the high energy regime, then there are no ultraviolet divergencies in field theories, it is possible to quantize gravity, and the theory of matter plus gravity is free of divergencies or renormalizable. If the space is higher dimensional at cosmological scales, then some cosmological problems (including the cosmological constant problem can be attacked from a completely new perspective. In this paper, we construct an explicit model of “evolving dimensions” in which the dimensions open up as the temperature of the universe drops. We adopt the string theory framework in which the dimensions are fields that live on the string worldsheet, and add temperature dependent mass terms for them. At the Big Bang, all the dimensions are very heavy and are not excited. As the universe cools down, dimensions open up one by one. Thus, the dimensionality of the space we live in depends on the energy or temperature that we are probing. In particular, we provide a kinematic Brandenberger–Vafa argument for how a discrete causal set, and eventually a continuum (3+1-dim spacetime along with Einstein gravity emerges in the Infrared from the worldsheet action. The (3+1-dim Planck mass and the string scale become directly related, without any compactification. Amongst other predictions, we argue that LHC might be blind to new physics even if it comes at the TeV scale. In contrast, cosmic ray experiments, especially those that can register the very beginning of the shower, and collisions with high multiplicity and density of particles, might be sensitive to the dimensional cross-over.

  12. Evolvable Cryogenics (ECRYO) Pressure Transducer Calibration Test

    Science.gov (United States)

    Diaz, Carlos E., Jr.

    2015-01-01

    This paper provides a summary of the findings of recent activities conducted by Marshall Space Flight Center's (MSFC) In-Space Propulsion Branch and MSFC's Metrology and Calibration Lab to assess the performance of current "state of the art" pressure transducers for use in long duration storage and transfer of cryogenic propellants. A brief historical narrative in this paper describes the Evolvable Cryogenics program and the relevance of these activities to the program. This paper also provides a review of three separate test activities performed throughout this effort, including: (1) the calibration of several pressure transducer designs in a liquid nitrogen cryogenic environmental chamber, (2) the calibration of a pressure transducer in a liquid helium Dewar, and (3) the calibration of several pressure transducers at temperatures ranging from 20 to 70 degrees Kelvin (K) using a "cryostat" environmental chamber. These three separate test activities allowed for study of the sensors along a temperature range from 4 to 300 K. The combined data shows that both the slope and intercept of the sensor's calibration curve vary as a function of temperature. This homogeneous function is contrary to the linearly decreasing relationship assumed at the start of this investigation. Consequently, the data demonstrates the need for lookup tables to change the slope and intercept used by any data acquisition system. This ultimately would allow for more accurate pressure measurements at the desired temperature range. This paper concludes with a review of a request for information (RFI) survey conducted amongst different suppliers to determine the availability of current "state of the art" flight-qualified pressure transducers. The survey identifies requirements that are most difficult for the suppliers to meet, most notably the capability to validate the sensor's performance at temperatures below 70 K.

  13. Giant migrating contractions during defecation in the dog colon.

    Science.gov (United States)

    Karaus, M; Sarna, S K

    1987-04-01

    The colonic motor correlates of defecation were studied in 5 conscious dogs. A set of six strain-gauge transducers were implanted on the colon of each dog. An implanted cannula gave access to the terminal ileum. During a total control recording period of 230 h we observed 12 large-amplitude contractions that occurred spontaneously in the proximal colon and migrated caudad. We called them giant migrating contractions. The mean amplitude of these contractions was 2.8 times larger than the mean peak amplitude of phasic contractions during colonic motor complexes. The following stimuli were applied to induce defecation: 2 mg/kg guanethidine (i.v.), 30 micrograms/kg neostigmine (i.v.), 1-4 ml/kg castor oil (p.o.), 200 ml of 25% glucose (into ileum), and rectal distention by a balloon (120 ml). In 85% of experiments with guanethidine, neostigmine, glucose, and castor oil, giant migrating contractions occurred before defecation. The giant migrating contractions migrated over the entire colon or a part of its length. The migration velocity varied from 0.2 to 3.2 cm/s (mean +/- SE, 0.82 +/- 0.1 cm/s). In 11% of the experiments, giant contractions occurred almost simultaneously at different recording sites at the time of defecation. In 4% of the experiments giant contractions occurred only at a single site. Balloon expulsion was only rarely accompanied by giant contractions in the colon, and then occurred only at a distal site and did not migrate. We conclude that the colon has spontaneous but infrequent large-amplitude caudad-migrating contractions. These contractions may be the motor equivalent of mass movements. Defecation is usually preceded by colonic giant migrating contractions. The giant migrating contractions may provide a major force for defecation and be partially responsible for the evacuation of the colon during defecation. However, evacuation of contents such as a balloon seems to be possible without giant migrating contractions.

  14. From K giants to G dwarfs: stellar lifetime effects on metallicity distributions derived from red giants

    Science.gov (United States)

    Manning, Ellen M.; Cole, Andrew A.

    2017-11-01

    We examine the biases inherent to chemical abundance distributions when targets are selected from the red giant branch (RGB), using simulated giant branches created from isochrones. We find that even when stars are chosen from the entire colour range of RGB stars and over a broad range of magnitudes, the relative numbers of stars of different ages and metallicities, integrated over all stellar types, are not accurately represented in the giant branch sample. The result is that metallicity distribution functions derived from RGB star samples require a correction before they can be fitted by chemical evolution models. We derive simple correction factors for over- and under-represented populations for the limiting cases of single-age populations with a broad range of metallicities and of continuous star formation at constant metallicity; an important general conclusion is that intermediate-age populations (≈1-4 Gyr) are over-represented in RGB samples. We apply our models to the case of the Large Magellanic Cloud bar and show that the observed metallicity distribution underestimates the true number of metal-poor stars by more than 25 per cent; as a result, the inferred importance of gas flows in chemical evolution models could potentially be overestimated. The age- and metallicity-dependences of RGB lifetimes require careful modelling if they are not to lead to spurious conclusions about the chemical enrichment history of galaxies.

  15. Spectrum of giant cells and its significance on FNAC in breast lesions

    OpenAIRE

    S Dayal; M Mathur; V Gupta

    2017-01-01

    Fine needle aspiration of breast is being performed from last several years. It is not uncommon to find giant cell on FNAC of breast smears .Giant cells arises from monocyte / macrophage lineage which are capable of fusion to form multinucleated giant cell. The common giant cell seen in breast on fna smears are foreign body , Langhan’s type , stromal giant cells , tumor giant cells and osteoclastic giant cell . It arises in benign as well as malignant lesions of the breast. Hence, their recog...

  16. Combinatorics of giant hexagonal bilayer hemoglobins.

    Science.gov (United States)

    Hanin, L G; Vinogradov, S N

    2000-01-01

    The paper discusses combinatorial and probabilistic models allowing to characterize various aspects of spacial symmetry and structural heterogeneity of the giant hexagonal bilayer hemoglobins (HBL Hb). Linker-dodecamer configurations of HBL are described for two and four linker types (occurring in the two most studied HBL Hb of Arenicola and Lumbricus, respectively), and the most probable configurations are found. It is shown that, for HBL with marked dodecamers, the number of 'normal-marked' pairs of dodecamers in homological position follows a binomial distribution. The group of symmetries of the dodecamer substructure of HBL is identified with the dihedral group D6. Under natural symmetry assumptions, the total dipole moment of the dodecamer substructure of HBL is shown to be zero. Biological implications of the mathematical findings are discussed.

  17. Laparoscopic extirpation of giant adrenal ganglioneuroma

    Directory of Open Access Journals (Sweden)

    George P Abraham

    2014-01-01

    Full Text Available Laparoscopic adrenalectomy is the standard of care for management of adrenal neoplasms. However, large sized adrenal lesions are considered as relative contraindication for laparoscopic extirpation. We report laparoscopic excision of giant ganglioneuroma of adrenal gland in a 33-year-old female patient. Patient was presented with left loin pain of 2 months duration. Computed tomography (CT scan was suggestive of non-enhancing left suprarenal mass measuring 17 × 10 cm. Preoperative endocrine evaluation ruled out functional adrenal tumor. Patient underwent transperitoneal excision of suprarenal mass. The lesion could be completely extirpated laparoscopically. Duration of surgery was 250 minutes. Estimated blood loss was 230 milliliters. Specimen was extracted through pfannenstiel incision. No significant intraoperative or postoperative happenings were recorded. Microscopic features were suggestive of ganglioneuroma of adrenal gland.

  18. Giant vacuum forces via transmission lines.

    Science.gov (United States)

    Shahmoon, Ephraim; Mazets, Igor; Kurizki, Gershon

    2014-07-22

    Quantum electromagnetic fluctuations induce forces between neutral particles, known as the van der Waals and Casimir interactions. These fundamental forces, mediated by virtual photons from the vacuum, play an important role in basic physics and chemistry and in emerging technologies involving, e.g., microelectromechanical systems or quantum information processing. Here we show that these interactions can be enhanced by many orders of magnitude upon changing the character of the mediating vacuum modes. By considering two polarizable particles in the vicinity of any standard electric transmission line, along which photons can propagate in one dimension, we find a much stronger and longer-range interaction than in free space. This enhancement may have profound implications on many-particle and bulk systems and impact the quantum technologies mentioned above. The predicted giant vacuum force is estimated to be measurable in a coplanar waveguide line.

  19. Giant aneurysmal bone cyst of the mandible.

    Science.gov (United States)

    Hebbale, Manjula; Munde, Anita; Maria, Anisha; Gawande, Pushkar; Halli, Rajshekhar

    2011-03-01

    The aneurysmal bone cyst is a type of pseudocysts of the jaw. It is a nonneoplastic lesion of the bone, characterized by replacement with fibro-osseous tissue containing blood-filled sinusoidal or cavernous spaces. The lesion remains a relatively uncommon finding in the facial bones, and the cause and pathogenesis are yet to be elucidated. Aneurysmal bone cyst was first described as a distinct clinical and pathologic entity by Jaffe and Lichtenstein in 1942. Aneurysmal bone cyst comprises 1.5% of all nonodontogenic cysts of the jaws and 1.9% of all aneurysmal bone cysts of skeleton. A rare case of giant aneurysmal bone cyst of mandible in a 10-year-old child is presented, which was managed by surgical curettage with a long-term follow-up.

  20. Giant radicular cyst of the maxilla.

    Science.gov (United States)

    Deshmukh, Jeevanand; Shrivastava, Ratika; Bharath, Kashetty Panchakshari; Mallikarjuna, Rachappa

    2014-05-02

    Radicular cysts are inflammatory odontogenic cysts of tooth bearing areas of the jaws. Most of these lesions involve the apex of offending tooth and appear as well-defined radiolucencies. Owing to its clinical characteristics similar to other more commonly occurring lesions in the oral cavity, differential diagnosis should include dentigerous cyst, ameloblastoma, odontogenic keratocyst, periapical cementoma and Pindborg tumour. The present case report documents a massive radicular cyst crossing the midline of the palate. Based on clinical, radiographical and histopathological findings, the present case was diagnosed as an infected radicular cyst. The clinical characteristics of this cyst could be considered as an interesting and unusual due to its giant nature. The lesion was surgically enucleated along with the extraction of the associated tooth; preservation of all other teeth and vital structures, without any postoperative complications and satisfactory healing, was achieved.

  1. Giant Tarsal Keratinous Cyst Mimicking Chalazion

    Directory of Open Access Journals (Sweden)

    Melis Palamar Onay

    2013-04-01

    Full Text Available Reports on keratinous cysts involving the tarsal plate are very rare. Herein, we present a 69-year-old male patient with a giant tarsal keratinous cyst of the right upper eyelid who was misdiagnosed as chalazion of the eyelid. Interventional case report with cytopathologic correlation. Due to recurrence after the surgery for presumed chalazion, the patient was referred to our clinic for tumor evaluation. In the second surgery, which was performed in our clinic, the lesion was found to have a fine capsule and was totally excised. Histopathologic examination revealed keratinous cyst of the tarsal plate. Keratinous cyst must be considered in the differential diagnosis of tarsal plate lesions, as the curettage of the keratinous cyst might result in multiple recurrences. (Turk J Ophthalmol 2013; 43: 138-9

  2. Giant biliary cystadenoma: a case report.

    Science.gov (United States)

    Cecka, F; Ferko, A; Subrt, Z; Jon, B

    2011-01-01

    Biliary cystadenoma is a very rare benign cystic tumour of the liver. Fewer than 150 cases have been described in the literature so far. The authors present a case of a 29-year-old female with a giant intrahepatic biliary cystadenoma who presented with abdominal pain and obstructive jaundice. The patient was treated with left hepatectomy and now 12 months after the surgery she is in good condition with no signs of recurrence of the disease. Clinical presentation of biliary cystadenoma is not specific. Diagnosis is based on imaging methods, mainly ultrasound and CT scan. However, it is often misdiagnosed. For treatment, radical resection is advocated because a biliary cystadenoma is considered to be a premalignant lesion. The prognosis of biliary cystadenoma after complete resection is excellent. Nevertheless, there is a risk of recurrence or malignant transformation after incomplete resection.

  3. The magnetodiscs and aurorae of giant planets

    CERN Document Server

    Achilleos, Nicholas; Arridge, Chris; Badman, Sarah; Delamere, Peter; Grodent, Denis; Kivelson, Margaret; Louarn, Philippe

    2016-01-01

    Readers will find grouped together here the most recent observations, current theoretical models and present understanding of the coupled atmosphere, magnetosphere and solar wind system. The book begins with a general discussion of mass, energy and momentum transport in magnetodiscs. The physics of partially ionized plasmas of the giant planet magnetodiscs is of general interest throughout the field of space physics, heliophysics and astrophysical plasmas; therefore, understanding the basic physical processes associated with magnetodiscs has universal applications. The second chapter characterizes the solar wind interaction and auroral responses to solar wind driven dynamics. The third chapter describes the role of magnetic reconnection and the effects on plasma transport. Finally, the last chapter characterizes the spectral and spatial properties of auroral emissions, distinguishing between solar wind drivers and internal driving mechanisms. The in-depth reviews provide an excellent reference for future re...

  4. Giant lupus vulgaris: A rare presentation.

    Science.gov (United States)

    Sacchidanand, S; Sharavana, S; Mallikarjun, M; Nataraja, H V

    2012-01-01

    Cutaneous tuberculosis continues to be an important public health problem even with the availability of highly effective anti-tuberculous drugs. It constitutes 0.1% of all cases of extrapulmonary tuberculosis. Lupus vulgaris is the most common form of cutaneous tuberculosis that occurs in previously sensitized individuals with a moderate degree of immunity against tubercle bacilli. The different types of lupus vulgaris include plaque, ulcerative, vegetative, papular and nodular, and tumor forms. A 40-year-old man presented with large multiple plaques over right upper limb, right side of chest and back, and right lower limb for the past 30 years. Histopathology showed numerous noncaseating granulomas with Langhan's type of giant cells. The Mantoux test showed strong positivity and there was excellent response to anti-tuberculous treatment. This case is being reported because of its extreme chronicity of 30 years duration, unusually large size and multiplicity of lesions.

  5. Giant thermal Hall effect in multiferroics

    Science.gov (United States)

    Ideue, T.; Kurumaji, T.; Ishiwata, S.; Tokura, Y.

    2017-08-01

    Multiferroics, in which dielectric and magnetic orders coexist and couple with each other, attract renewed interest for their cross-correlated phenomena, offering a fundamental platform for novel functionalities. Elementary excitations in such systems are strongly affected by the lattice-spin interaction, as exemplified by the electromagnons and the magneto-thermal transport. Here we report an unprecedented coupling between magnetism and phonons in multiferroics, namely, the giant thermal Hall effect. The thermal transport of insulating polar magnets (ZnxFe1-x)2Mo3O8 is dominated by phonons, yet extremely sensitive to the magnetic structure. In particular, large thermal Hall conductivities are observed in the ferrimagnetic phase, indicating unconventional lattice-spin interactions and a new mechanism for the Hall effect in insulators. Our results show that the thermal Hall effect in multiferroic materials can be an effective probe for strong lattice-spin interactions and provide a new tool for magnetic control of thermal currents.

  6. Characterizing Cool Giant Planets in Reflected Light

    Science.gov (United States)

    Marley, Mark

    2016-01-01

    While the James Webb Space Telescope will detect and characterize extrasolar planets by transit and direct imaging, a new generation of telescopes will be required to detect and characterize extrasolar planets by reflected light imaging. NASA's WFIRST space telescope, now in development, will image dozens of cool giant planets at optical wavelengths and will obtain spectra for several of the best and brightest targets. This mission will pave the way for the detection and characterization of terrestrial planets by the planned LUVOIR or HabEx space telescopes. In my presentation I will discuss the challenges that arise in the interpretation of direct imaging data and present the results of our group's effort to develop methods for maximizing the science yield from these planned missions.

  7. Structured surfaces for a giant liquid slip.

    Science.gov (United States)

    Lee, Choongyeop; Choi, Chang-Hwan; Kim, Chang-Jin Cj

    2008-08-08

    We study experimentally how two key geometric parameters (pitch and gas fraction) of textured hydrophobic surfaces affect liquid slip. The two are independently controlled on precisely fabricated microstructures of posts and grates, and the slip length of water on each sample is measured using a rheometer system. The slip length increases linearly with the pitch but dramatically with the gas fraction above 90%, the latter trend being more pronounced on posts than on grates. Once the surfaces are designed for very large slips (>20 microm), however, further increase is not obtained in regular practice because the meniscus loses its stability. By developing near-perfect samples that delay the transition from a dewetted (Cassie) to a wetted (Wenzel) state until near the theoretical limit, we achieve giant slip lengths, as large as 185 microm.

  8. Giant Photogalvanic Effect in Noncentrosymmetric Plasmonic Nanoparticles

    Directory of Open Access Journals (Sweden)

    Sergei V. Zhukovsky

    2014-09-01

    Full Text Available Photoelectric properties of noncentrosymmetric, similarly oriented metallic nanoparticles embedded in a homogeneous semiconductor matrix are theoretically studied. Because of the asymmetric shape of the nanoparticle boundary, photoelectron emission acquires a preferred direction, resulting in a photocurrent flow in that direction when nanoparticles are uniformly illuminated by a homogeneous plane wave. This effect is a direct analogy of the photogalvanic (or bulk photovoltaic effect known to exist in media with noncentrosymmetric crystal structure, such as doped lithium niobate or bismuth ferrite, but is several orders of magnitude stronger. Termed the giant plasmonic photogalvanic effect, the reported phenomenon is valuable for characterizing photoemission and photoconductive properties of plasmonic nanostructures and can find many uses for photodetection and photovoltaic applications.

  9. Giant Photogalvanic Effect in Noncentrosymmetric Plasmonic Nanoparticles

    DEFF Research Database (Denmark)

    Zhukovsky, Sergei; Babicheva, Viktoriia; Evlyukhin, Andrey B.

    2014-01-01

    Photoelectric properties of noncentrosymmetric, similarly oriented metallic nanoparticles embedded in a homogeneous semiconductor matrix are theoretically studied. Because of the asymmetric shape of the nanoparticle boundary, photoelectron emission acquires a preferred direction, resulting...... in a photocurrent flow in that direction when nanoparticles are uniformly illuminated by a homogeneous plane wave. This effect is a direct analogy of the photogalvanic (or bulk photovoltaic) effect known to exist in media with noncentrosymmetric crystal structure, such as doped lithium niobate or bismuth ferrite......, but is several orders of magnitude stronger. Termed the giant plasmonic photogalvanic effect, the reported phenomenon is valuable for characterizing photoemission and photoconductive properties of plasmonic nanostructures and can find many uses for photodetection and photovoltaic applications....

  10. Giant magnetoresistance An ab-initio description

    CERN Document Server

    Binder, J

    2000-01-01

    A new theoretical concept to study the microscopic origin of Giant Magnetoresistance (GMR) from first principles is presented. The method is based on ab-initio electronic structure calculations within the spin density functional theory using a Screened KORRINGA-KOHNROSTOKER method. Scattering at impurity atoms in the multilayers is described by means of a GREEN's-function method. The scattering potentials are calculated self-consistently. The transport properties are treated quasi-classically solving the BOLTZMANN equation including the electronic structure of the layered system and the anisotropic scattering. The solution of the BOLTZMANN equation is performed iteratively taking into account both scattering out and scattering in terms (vertex corrections). The method is applied to Co/Cu and Fe/Cr multilayers. Trends of scattering cross sections, residual resistivities and GMR ratios are discussed for various transition metal impurities at different positions in the Co/Cu or Fe/Cr multilayers. Furthermore the...

  11. Giant cell tumor of dorsal vertebral body

    Directory of Open Access Journals (Sweden)

    Rakesh Redhu

    2012-01-01

    Full Text Available A 30-year-old female patient presented with complaints of backache, weakness in both lower limbs and bladder/bowel dysfunction. Imaging showed an osteolytic lesion at tenth dorsal (D10 vertebra with anterior compression on the spinal cord. Complete intralesional tumor excision with reconstruction was carried out using the anterolateral extrapleural approach. Histopathological examination was suggestive of giant cell tumor (GCT. Because of complete intralesional tumor excision and fear of post-radiation osteonecrosis of bone used for delayed bony union, a conservative approach was used, and radiation therapy was not given. After one year of follow-up patient is doing well without any recurrence of the tumor and is ambulant with support. GCT of dorsal vertebral body is an uncommon entity and total en bloc excision is difficult. Therefore, the treatment strategy is not well-defined. We discuss in brief about incidence, presentation and various treatment modalities available for spinal GCT.

  12. Variable Red Giants--The MACHO View

    Energy Technology Data Exchange (ETDEWEB)

    Keller, S C; Cook, K H

    2003-01-03

    The authors present a study of the MACHO red variable population in the Large Magellanic Cloud. This study reveals six period-luminosity relations among the red variable population. Only two of these were known prior to MACHO. The results are consistent with Mira pulsation in the fundamental mode. A sequence comprising 26% of the red variable population can not be explained by pulsation. They propose a dust {kappa}-mechanism in the circumstellar environment is responsible for the long period variation of these objects. The luminosity function of the variables shows a sharp edge at the tip of the red giant branch (TRGB). This is the first clear indication of a population of variable stars within the immediate vicinity of the TRGB. The results indicate this population amounts to 8% of the RGB population near the TRGB.

  13. Giant esophageal epiphrenic diverticulum: presentation and treatment.

    Science.gov (United States)

    Santos, Marcelo Protásio Dos; Akerman, Denise; Santos, Caio Pasquali Dias Dos; Santos, Paulo Vicente Dos; Radtke, Marcos Claudio; Beraldo, Fernando Bray; Gonçalves, José Eduardo

    2017-09-21

    Epiphrenic diverticulum is a rare disease associated with esophageal motor disorders that is usually asymptomatic and has a well-established surgical indication. We report a case of giant epiphrenic diverticulum in a 59-year-old symptomatic woman who was diagnosed after underwent complementary exams. Because of her symptoms, the surgical treatment was chosen, and esophageal diverticulectomy was performed along with laparoscopic cardiomyotomy and anterior partial fundoplication. RESUMO O divertículo epifrênico é uma patologia rara associada a distúrbios motores esofágicos e, frequentemente, assintomática, tendo indicações cirúrgicas bem estabelecidas. Relatamos um caso de divertículo epifrênico gigante em paciente de 59 anos, sexo feminino, sintomática, diagnosticada por exames complementares. Devido à sintomatologia, optou-se por tratamento cirúrgico, sendo realizada a diverticulectomia esofágica com cardiomiotomia e fundoplicatura parcial anterior laparoscópica.

  14. A Giant Hemangioma of the Tongue

    Directory of Open Access Journals (Sweden)

    Babak Saedi

    2011-01-01

    Full Text Available Introduction: Vascular abnormalities are relatively uncommon lesions, but head and neck is a common region for vascular malformation which is classified as benign tumors. In this paper, the authors report a rare presentation of vascular malformation in the tongue and its managements. Case Report: An 18 months 2 old child presented with a giant mass of tongue which caused functional and aesthetic problem. The rapid growth pattern of cavernous hemangioma was refractory to corticosteroid. The lesion was excised without any complication. Since the mass was so huge that not only filled entire oral cavity but was protruding outside, airway management was a great challenge for anesthesia plan and at the same time surgical technique was difficult to select. Conclusion: Despite different recommended modalities in managing hemangiomas of the tongue, in cases of huge malformations, surgery could be the mainstay treatment and provided that critical care measures are taken in to account, could be performed very safely.

  15. Giant and thrombosed left ventricular aneurysm.

    Science.gov (United States)

    de Agustin, Jose Alberto; de Diego, Jose Juan Gomez; Marcos-Alberca, Pedro; Rodrigo, Jose Luis; Almeria, Carlos; Mahia, Patricia; Luaces, Maria; Garcia-Fernandez, Miguel Angel; Macaya, Carlos; de Isla, Leopoldo Perez

    2015-07-26

    Left ventricular aneurysms are a frequent complication of acute extensive myocardial infarction and are most commonly located at the ventricular apex. A timely diagnosis is vital due to the serious complications that can occur, including heart failure, thromboembolism, or tachyarrhythmias. We report the case of a 78-year-old male with history of previous anterior myocardial infarction and currently under evaluation by chronic heart failure. Transthoracic echocardiogram revealed a huge thrombosed and calcified anteroapical left ventricular aneurysm. Coronary angiography demonstrated that the left anterior descending artery was chronically occluded, and revealed a big and spherical mass with calcified borders in the left hemithorax. Left ventriculogram confirmed that this spherical mass was a giant calcified left ventricular aneurysm, causing very severe left ventricular systolic dysfunction. The patient underwent cardioverter-defibrillator implantation for primary prevention.

  16. Giant cell tumour of extensor tendon sheath: Preventing recurrence

    Directory of Open Access Journals (Sweden)

    S S Shirol

    2012-01-01

    Full Text Available Giant Cell Tumour of tendon sheath is relatively rare tumour with an overall incidence of around 1 in 50,000 individuals. Marginal excision of giant cell tumour of the tendon sheath is the treatment of choice. It is also the commonest hand lesion to recur after excision. The incidence of local recurrence is high, ranging from 9-44%. Here we present a case report of a giant cell tumour of extensor tendon sheath in hand which was successfully treated with special emphasis on ways of prevention of recurrence.

  17. Spin isovector giant resonances in (n,p) reactions

    Energy Technology Data Exchange (ETDEWEB)

    Spicer, B.M.

    1997-12-31

    The present status of the study of spin-flip isovector giant resonances, using the (n,p) charge exchange reaction, is reviewed. After a brief history of the discovery of these giant resonances, a critical appraisal of the interpretation of the data in terms of giant resonances is given, along with some of the theoretical advances that impact on the interpretation of these data. A sampling of the results obtained for typical targets is given, followed by the interpretation of these results. A brief statement is made concerning the way forward in experimental technique for nuclear structure research using charge exchange reactions. 54 refs., 18 figs.

  18. An unusual cause of acute pulmonary embolism: giant hepatic hemangioma

    Directory of Open Access Journals (Sweden)

    Hatice Duygu Hatice Duygu Bas

    2016-06-01

    Full Text Available Hemangiomas are the most common benign hepatic tumors and are usually asymptomatic. Lesions measuring more than 4 cm in diameter are known as “giant hemangiomas” and may cause various symptoms or complications depending on the size, the location, and the degree of compression of adjacent structures. Pulmonary embolism is a very rare complication of giant hepatic hemangiomas. In this case report, we describe a patient with acute pulmonary emboli, which presumably originated from laminar thrombi in the inferior vena cava caused by compression by giant hepatic hemangiomas.

  19. Giant scrotal lymphedema of unclear etiology: a case report

    Directory of Open Access Journals (Sweden)

    Rahman Ganiyu A

    2009-05-01

    Full Text Available Abstract Introduction Scrotal lymphedema is common in the tropics and subtropics. The giant variants can cause a lot of physical disability and psychological disturbances. Case presentation We present a 25-year-old Nigerian male with giant scrotal lymphedema with severe debilitating symptoms, immobility and emotional disturbance. He benefited from a modified Charles' procedure and reconstruction of the penile shaft using a split-thickness skin graft. Conclusion Giant scrotal lymphedema related to poverty, ignorance and neglect, is amenable to surgery. Surgery provides a cosmetically acceptable and functionally satisfying outcome.

  20. Emergency endovascular coiling of a ruptured giant splenic artery aneurysm

    Directory of Open Access Journals (Sweden)

    Erika Wernheden, MD

    2017-12-01

    Full Text Available Splenic artery aneurysms (SAAs are the third most common abdominal aneurysm. Endovascular treatment of SAAs is preferred, and coiling is the most commonly used technique. Ruptured giant (>5 cm SAAs are usually treated with open surgery including splenectomy. We present a rare case of a ruptured 15-cm giant SAA in an 84-year-old woman treated successfully with emergency endovascular coiling. To our knowledge, this is one of the few reports of emergency endovascular treatment for ruptured giant SAA.

  1. Giant Rings in the Cosmic Microwave Background Sky

    Science.gov (United States)

    Kovetz, Ely D.; Ben-David, Assaf; Itzhaki, Nissan

    2010-11-01

    We find a unique direction in the cosmic microwave background sky around which giant rings have an anomalous mean temperature profile. This direction is in very close alignment with the afore measured anomalously large bulk flow direction. Using Monte Carlo simulations, we estimate the significance of the giant rings at the 3σ level and the alignment with the bulk flow at 2.5σ. We argue that a cosmic defect seeded by a pre-inflationary particle could explain the giant rings, the large bulk flow, and their alignment.

  2. Varicella zoster virus and giant cell arteritis.

    Science.gov (United States)

    Gilden, Don; Nagel, Maria A

    2016-06-01

    Giant cell arteritis (GCA) is a serious disease and the most common cause of vasculitis in the elderly. Here, studies describing the recent discovery of varicella zoster virus (VZV) in the temporal arteries of patients with GCA are reviewed. GCA is characterized by severe headache/head pain and scalp tenderness. Many patients also have a history of vision loss, jaw claudication, polymyalgia rheumatica, fever, night sweats, weight loss, and fatigue. The erythrocyte sedimentation rate and C-reactive protein are usually elevated. Diagnosis is confirmed by temporal artery biopsy, which reveals vessel wall damage and inflammation, with multinucleated giant cells and/or epithelioid macrophages. Skip lesions are common. Importantly, temporal artery biopsies are pathologically negative in many clinically suspect cases. The present review highlights recent virological findings in temporal arteries from patients with pathologically verified GCA and in temporal arteries from patients who manifest clinical and laboratory features of GCA but whose temporal artery biopsies are pathologically negative for GCA. Virological analysis revealed that VZV is present in most GCA-positive and GCA-negative temporal artery biopsies, particularly in skip areas that correlate with adjacent GCA disease. The presence of VZV in GCA-positive and GCA-negative temporal arteries reflects the possible role of VZV in triggering the immunopathology of GCA and indicates that both groups of patients should be treated with antivirals in addition to corticosteroids. Whether oral antiviral agents and steroids are as effective as intravenous acyclovir and steroids, and the dosage and duration of treatment, remain to be determined.

  3. A giant planet around HD95086 ?

    Science.gov (United States)

    Rameau, Julien; Chauvin, Gaël; Lagrange, Anne-Marie; Meshkat, Tiffany; Boccaletti, Anthony; Quanz, Sascha P.; Bonnefoy, Mickaël; Bailey, Vanessa; Kenworthy, Matthew; Currie, Thayne; Girard, Julien H.; Delorme, Philippe; Desidera, Silvano; Dumas, Christophe; Mordasini, Christoph; Klahr, Hubert; Bonavita, Mariangela

    2013-07-01

    Understanding planetary systems formation and evolution has become one of the challenges in as- tronomy, since the discovery of the first exoplanet around the solar-type star 51 Peg in the 90's. While more than 800 planets (mostly giants) closer than a few AU have been identified with radial velocity and transit techniques, very few have been imaged and definitely confirmed around stars, at separations below a hundred of astronomical units. Direct imaging detection of exoplanet is indeed a major frontier in planetary astrophysics. It surveys a region of semi-major axes (> 5 AU) that is almost inaccessible to other methods. Moreover, the planets imaged so far orbit young stars; indeed the young planets are still hot and the planet-star contrasts are compatible with the detection limits currently achievable, in contrast with similar planets in older systems. Noticeably, the stars are of early-types, and surrounded by debris disks, i.e. disks populated at least by small grains with lifetimes so short that they must be permanently produced, probably by destruction (evaporation, collisions) of larger solid bodies. Consequently, every single discovery has a tremendous impact on the understanding of the formation, the dynamical evolution, and the physics of giant planets. In this context, I will present our recent discovery of one faint companion to a nearby, dusty, and young A-type star (at 56 AU projected separation). Background contaminants are rejected with high confidence level based on both astrometry and photometry with three dataset at more than a year-time-laps and two different wavelength regimes. From the system age (10 to 17 Myr) and from model-dependent luminosity estimates, we derive mass of 4 to 5 Jupiter mass. This planet is therefore the one with the lowest mass ever imaged around a star. Given its orbital and physical properties, I will discuss the implication on its atmosphere with respect to other imaged companions but also on its formation.

  4. Thermohaline mixing in evolved low-mass stars

    NARCIS (Netherlands)

    Cantiello, M.|info:eu-repo/dai/nl/304840866; Langer, N.|info:eu-repo/dai/nl/304829498

    2010-01-01

    Context. Thermohaline mixing has recently been proposed to occur in low-mass red giants, with large consequence for the chemical yields of low-mass stars. Aims. We investigate the role of thermohaline mixing during the evolution of stars between 1 M and 3 M , in comparison with other mixing

  5. Orthogonally Evolved AI to Improve Difficulty Adjustment in Video Games

    DEFF Research Database (Denmark)

    Hintze, Arend; Olson, Randal; Lehman, Joel Anthony

    2016-01-01

    (i.e. agents subject to fewer generations of evolution) make for easier opponents, while highly-evolved agents are more challenging to overcome. In this publication we test a new approach for difficulty adjustment in games: orthogonally evolved AI, where the player receives support from collaborating...... opponents. Furthermore, human interaction can modulate (and be informed by) the performance and behavior of collaborating agents. In this way, orthogonally evolved AI both facilitates smoother difficulty adjustment and enables new game experiences....

  6. Peripheral and Central Giant Cell Lesions in Children: Institutional Experience at Subharti Dental College and Hospital

    OpenAIRE

    Chandna, Preetika; Srivastava, Nikhil; Bansal, Vishal; Wadhwan, Vijay; Dubey, Prajesh

    2017-01-01

    Introduction: Giant cell lesions (GCG) are a group of varied lesions that contain a multitude of multinucleated, osteoclast like giant cells within connective tissue stroma. These include giant cell granulomas which may be central (CGCG), if they lie within the jaw bone, or, peripheral (PGCG) if they lie within the soft tissue. Giant cell granulomas comprised 9.29% of all oral lesions. This case series comprises of 5 giant cell lesions in children between the ages of 4 to 12 years. Materials ...

  7. Evolving R Coronae Borealis Stars with MESA

    Science.gov (United States)

    Clayton, Geoffrey C.; Lauer, Amber; Chatzopoulos, Emmanouil; Frank, Juhan

    2018-01-01

    being a WD. Solving the mystery of how the RCB stars evolve will lead to a better understanding of other important types of stellar merger events such as Type Ia SNe.

  8. Giant Urinary Bladder and Bilateral Giant Hydronephrosis due to Bladder Neck Obstruction: One Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Mohammed Fadl Tazi

    2012-01-01

    Full Text Available Bilateral hydronephrosis secondary to urinary obstruction leads to a buildup of back pressure in the urinary tract and may lead to impairment of renal function. Cases of giant hydronephrosis are rare and usually contain no more than 1-2 litres of fluid in the collecting system. Here, we report a rarely seen case with giant urinary bladder and bilateral giant hydronephrosis due to bladder neck obstruction which contains 4000 mL fluid in the collecting system of the kidney mimicking an ascites in an adult male.

  9. Remarks on thermodynamics and holography of moving giant gravitons

    Science.gov (United States)

    Youm, Donam

    2001-09-01

    In my previous work [Phys. Rev. D 63, 085010 (2001)], I showed that the brane universe on the giant graviton moving in the near-horizon background of the dilatonic D(6-p)-brane is described by mirage cosmology. We study the thermodynamic properties of the moving giant graviton by applying the thermodynamics of cosmology and the recently proposed holographic principles of cosmology. We find that the Fischler-Susskind holographic bound is satisfied by the closed brane universe on the moving giant graviton with p>3. The Bekenstein and the Hubble entropy bounds and the recently proposed Verlinde holographic principle applied to the brane universe on the giant graviton are also studied.

  10. Using giant African pouched rats to detect tuberculosis in human ...

    African Journals Online (AJOL)

    Using giant African pouched rats to detect tuberculosis in human sputum samples: 2010 findings. AM Mahoney, BJ Weetjens, C Cox, N Beyene, G Mgode, M Jubitana, D Kuipers, R Kazwala, GS Mfinanga, A Durgin, A Poling ...

  11. Bilateral giant inguinoscrotal Hernia: psychosocial issues and a new ...

    African Journals Online (AJOL)

    EB

    100.00%). All the patients (100.00%) had ... improved access to free surgical health care services particularly in rural African communities. Keywords: Bilateral giant inguinoscrotal hernia, classification, quality of life. African Health Sciences ...

  12. Length-weight relationship of Giant Oyster, Crassostrea gyphoides (Schlotheim)

    Digital Repository Service at National Institute of Oceanography (India)

    Chatterji, A.; Ansari, Z.A.; Ingole, B.S.; Parulekar, A.H.

    Relationship between shell length and total weight, shell weight and meat weight of giant oyster, Crassostrea gryphoides revealed that the growth of these parameters is very fast and significant. It indicates the suitability of the species concerned...

  13. Theories of the origin and evolution of the giant planets

    Science.gov (United States)

    Pollack, J. B.; Bodenheimer, P.

    1989-01-01

    Following the accretion of solids and gases in the solar nebula, the giant planets contracted to their present sizes over the age of the solar system. It is presently hypothesized that this contraction was rapid, but not hydrodynamic; at a later stage, a nebular disk out of which the regular satellites formed may have been spun out of the outer envelope of the contracting giant planets due to a combination of total angular momentum conservation and the outward transfer of specific angular momentum in the envelope. If these hypotheses are true, the composition of the irregular satellites directly reflects the composition of planetesimals from which the giant planets formed, while the composition of the regular satellites is indicative of the composition of the less volatile components of the outer envelopes of the giant planets.

  14. Parasitic Infections of the African Giant Rat ( Cricetomys Gambianus ...

    African Journals Online (AJOL)

    Cricetomys gambianus) was undertaken using standard parasitological methods. Of the 100 wild giant rats captured, 22(43.14%) males and 16(32.65%) females harboured gastrointestinal parasites. Similarly, 14(31.11%) juveniles and ...

  15. Springer--Germany's Most Remorselessly Criticized Publishing Giants.

    Science.gov (United States)

    Hollstein, Milton

    1982-01-01

    Argues that the success of West Germany's publishing giant, Axel Springer Verlag, can be attributed to the technical excellence of its products and to the fact that these products reflect the mainstream of German thought. (FL)

  16. Metastatic giant basal cell carcinoma: a case report | Khadija | Pan ...

    African Journals Online (AJOL)

    ... characterised by a slow growing behavior, metastasis are extremely rare, and it ... develops to a giant basal cell carcinoma,resulting ofpatient's negligence. ... cell carcinoma metastaticin lung occurringin a 79 years old male patient, with a ...

  17. Evidence of cellulose metabolism by the giant panda gut microbiome

    National Research Council Canada - National Science Library

    Lifeng Zhu; Qi Wu; Jiayin Dai; Shanning Zhang; Fuwen Wei

    2011-01-01

    The giant panda genome codes for all necessary enzymes associated with a carnivorous digestive system but lacks genes for enzymes needed to digest cellulose, the principal component of their bamboo diet...

  18. Giant pandas can discriminate the emotions of human facial pictures

    National Research Council Canada - National Science Library

    Youxu Li; Qiang Dai; Rong Hou; Zhihe Zhang; Peng Chen; Rui Xue; Feifei Feng; Chao Chen; Jiabin Liu; Xiaodong Gu; Zejun Zhang; Dunwu Qi

    2017-01-01

    Previous studies have shown that giant pandas (Ailuropoda melanoleuca) can discriminate face-like shapes, but little is known about their cognitive ability with respect to the emotional expressions of humans...

  19. Histogenesis of the development of Langhans' giant cells.

    Science.gov (United States)

    Zółtowska, A

    1986-01-01

    Microscopic analysis of the development of Langhans' giant cells in lymph nodes of hyperimmunized animals was performed. It seems that they originate from the primitive mesenchymal cells, arranged along the blood vessels especially along the capillaries.

  20. Population dynamics and potential yield of three species of giant ...

    African Journals Online (AJOL)

    Population dynamics and potential yield of three species of giant winkles in the Western Cape, South Africa. ... African Journal of Marine Science ... Because previous studies on the harvesting potential of T. sarmaticus off the Western Cape ...

  1. ON THE SURVIVAL OF BROWN DWARFS AND PLANETS ENGULFED BY THEIR GIANT HOST STAR

    Energy Technology Data Exchange (ETDEWEB)

    Passy, Jean-Claude; Mac Low, Mordecai-Mark [Department of Astrophysics, American Museum of Natural History, New York, NY (United States); De Marco, Orsola [Department of Physics and Astronomy, Macquarie University, Sydney, NSW (Australia)

    2012-11-10

    The recent discovery of two Earth-mass planets in close orbits around an evolved star has raised questions as to whether substellar companions can survive encounters with their host stars. We consider whether these companions could have been stripped of significant amounts of mass during the phase when they orbited through the dense inner envelopes of the giant. We apply the criterion derived by Murray et al. for disruption of gravitationally bound objects by ram pressure to determine whether mass loss may have played a role in the histories of these and other recently discovered low-mass companions to evolved stars. We find that the brown dwarf and Jovian-mass objects circling WD 0137-349, SDSS J08205+0008, and HIP 13044 are most unlikely to have lost significant mass during the common envelope phase. However, the Earth-mass planets found around KIC 05807616 could well be the remnants of one or two Jovian-mass planets that lost extensive mass during the common envelope phase.

  2. Chlorine Isotope Ratios in M Giants and S Stars

    Science.gov (United States)

    Maas, Zachary; Pilachowski, C. A.

    2018-01-01

    Chlorine is an odd-Z, light element that has been poorly studied in stars. Recently, the first stellar abundance measurements of the isotopologue 35Cl were made and the 35Cl/37Cl ratio was derived in RZ Ari (Maas et al. 2016). Additional abundance measurements are necessary to understand the Galactic chemical evolution and complex nucleosynthesis of Cl. The Cl isotope ratio in particular is important in distinguishing contributions from different nucleosynthesis sites to the surface abundances of stars. For example, current nucloesynthesis models predict that both isotopes of Cl are produced primarily during core collapse supernovae (CCSNe) with the energy and progenitor mass impacting the isotopic ratio of the ejected material. In addition to CCSNe, 37Cl is formed by the s-process both in massive stars and in AGB stars, and 35Cl may be produced from neutrino spallation. Understanding the formation of the Cl isotopes is also important to studies of the interstellar medium (ISM). A range of Cl isotope ratios mainly between 2 - 3.5 have been measured in star forming regions, in the circumstellar envelopes of evolved stars, and in proto-stellar cores using Cl bearing molecules. Additional measurements of the Cl isotope ratio in nearby stars will test nucleosynthesis models and allow comparisons with the range of isotope ratios observed in the ISM.We build on the results of Maas et al. (2016) by measuring the Cl isotope ratio in six M giants and four S stars using R~50,000 resolution spectra from Phoenix on Gemini South. We find no significant difference between the average Cl isotope ratios in the M stars and S stars and our measurements are consistent with the range of values seen in the ISM. We also find the average Cl ratio to be larger than the predicted isotope ratio of 1.8 for the solar neighborhood. Finally, two S stars, GG Pup and WY Pyx, show anomalously strong HCl features with equivalent widths ~3-5 times larger than the HCl features of other stars of

  3. Giant Renal Cyst Mimicking Ascites on Abdominal Ultrasonography

    Directory of Open Access Journals (Sweden)

    Martin Borovec

    2009-01-01

    Full Text Available An article describes diagnostic difficulties in patient with giant renal cyst, erroneously diagnosed as ascites on ultrasonographic examination. Patient was initially suspected to have disseminated intraabdominal malignancy. Abdominal paracentesis of supposed ascites was performed. The diagnosis of giant renal cyst was finally made by CT and patient was treated surgically. The limitations of ultrasonographic examination are pointed out are and a brief review of similar cases is given.

  4. Osteoclastic giant cell tumor of the pancreas: an immunohistochemical study

    DEFF Research Database (Denmark)

    Dizon, M A; Multhaupt, H A; Paskin, D L

    1996-01-01

    A case of an osteoclastic giant cell tumor of the pancreas is presented. Immunohistochemical studies were performed, which showed keratin (CAM, AE1) and epithelial membrane antigen positivity in the tumor cells. The findings support an epithelial origin for this tumor.......A case of an osteoclastic giant cell tumor of the pancreas is presented. Immunohistochemical studies were performed, which showed keratin (CAM, AE1) and epithelial membrane antigen positivity in the tumor cells. The findings support an epithelial origin for this tumor....

  5. Cerebellar giant cell glioblastoma multiforme in an adult

    OpenAIRE

    Sudhansu Sekhar Mishra; Sanjay Kumar Behera; Manmath Kumar Dhir; Satya Bhusan Senapati

    2014-01-01

    Cerebellar glioblastoma multiforme (GBM) is a rare tumor that accounts for only 1% of all cases of GBM and its giant cell variant is even much rarely encountered in adults. A case of cerebellar giant cell GBM managed at our institution reporting its clinical presentation, radiological and histological findings, and treatment instituted is described. In conjunction, a literature review, including particular issues, clinical data, advances in imaging studies, pathological characteristics, treat...

  6. Frequency of Giant Cell Lesions in Oral Biopsies

    Directory of Open Access Journals (Sweden)

    H. Mohajerani

    2009-12-01

    Full Text Available Objective: Oral lesions are among the important reasons for seeking dental care. Being frequently encountered, giant cell lesions form an important group of oral lesions. The epidemiologic data on these lesions, however, is scarce in Iran. The present study investigatedepidemiological and demographic characteristics of giant cell lesions in oral biopsies done in one of the largest oral pathology departments in Iran.Materials and Methods: This descriptive survey studied the existing biopsy records of 2265 patients referred to the Department of Oral Pathology in Shahid Beheshti Dental School from 1991 to 2002. Records with final diagnosis of giant cell lesion were identified.Data on type of lesion, distribution of lesions, the involved jaw, and patients' gender and age was extracted from these records.Results: In total, 144 giant cell lesions were identified. These lesions comprised peripheral giant cell granuloma (59.5%, central giant cell granuloma (36.6%, cherubism (2.5%,and aneurysmal bone cyst (1.4%. Most of the cases had been occurred among women(54.9%, in their second and third decades of life (49.4%. The anterior region of the mandible was the most common location of these lesions (26.2%. In approximately half of the cases, the first clinical diagnosis was similar to the histopathologic diagnosis.Conclusion: The giant cell lesions were more common in women and in the anterior region of the mandible. More commonly, they occurred in the second and third decades of life unilaterally. This study elucidates the epidemiologic data of giant cell lesions in Iranand the results can be helpful for dental scholars in various fields.

  7. Giant Cell Arteritis and Polymyalgia Rheumatica: 2016 Update

    OpenAIRE

    Gideon Nesher; Breuer, Gabriel S.

    2016-01-01

    Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are both more common among people of North European decent than among Mediterranean people. Women are 2–3 times more commonly affected. Giant cell arteritis and PMR are extremely rare before age 50 years. Polymyalgia rheumatica may be “isolated” or associated with GCA. There is increased expression of inflammatory cytokines in temporal arteries of PMR patients, without overt histological evidence of arteritis. One-third of “isolated”...

  8. Progress in thin films of giant magnetostrictive alloys

    Science.gov (United States)

    Uchida, Hirohisa; Matsumura, Yoshihito; Uchida, Haruhisa; Kaneko, Hideo

    2002-02-01

    This paper reviews recent progress in the study of thin films of giant magnetostrictive RFe 2 (R: rare earths) compounds with the C15 Laves phase. Results of magnetostrictive property of the compound films formed by vacuum flash evaporation, ion plating, electron beam evaporation, ion beam sputter, and DC-magnetron sputter are described. Magnetostrictive property of a new giant magnetostrictive Fe-Pd alloy film is compared with those of the RFe 2 films.

  9. Controllability of giant connected components in a directed network

    Science.gov (United States)

    Liu, Xueming; Pan, Linqiang; Stanley, H. Eugene; Gao, Jianxi

    2017-04-01

    When controlling a complex networked system it is not feasible to control the full network because many networks, including biological, technological, and social systems, are massive in size and complexity. But neither is it necessary to control the full network. In complex networks, the giant connected components provide the essential information about the entire system. How to control these giant connected components of a network remains an open question. We derive the mathematical expression of the degree distributions for four types of giant connected components and develop an analytic tool for studying the controllability of these giant connected components. We find that for both Erdős-Rényi (ER) networks and scale-free (SF) networks with p fraction of remaining nodes, the minimum driver node density to control the giant component first increases and then decreases as p increases from zero to one, showing a peak at a critical point p =pm . We find that, for ER networks, the peak value of the driver node density remains the same regardless of its average degree and that it is determined by pm . In addition, we find that for SF networks the minimum driver node densities needed to control the giant components of networks decrease as the degree distribution exponents increase. Comparing the controllability of the giant components of ER networks and SF networks, we find that when the fraction of remaining nodes p is low, the giant in-connected, out-connected, and strong-connected components in ER networks have lower controllability than those in SF networks.

  10. Giant coronary artery aneurysms complicating Kawasaki disease in Mexican children.

    Science.gov (United States)

    Garrido-García, Luis M; Morán-Villaseñor, Edna; Yamazaki-Nakashimada, Marco A; Cravioto, Patricia; Galván, Fernando

    2018-03-01

    One of the most important complications of Kawasaki disease is the development of giant coronary aneurysms. Risk factors for their development are still not clear. A retrospective analysis was conducted at the National Institute of Paediatrics in Mexico City, Mexico. It included all patients with a diagnosis of acute Kawasaki disease between August, 1995 and August, 2015. Clinical and laboratory findings, as well as echocardiographic measurements, were recorded. Patients with giant coronary aneurysms (z-score⩾10) were compared with the rest of the patients. A value of pKawasaki disease. Of them, 34 developed giant coronary aneurysms during the acute stage of the disease. In the multivariate analysis, patients younger than 1 year, those with a higher duration of illness at the time of diagnosis, and those who received additional intravenous immunoglobulin showed a significantly higher frequency of giant coronary aneurysms. One of the main factors associated with the development of giant coronary aneurysms was the delay in the diagnosis of Kawasaki disease. This finding highlights the importance of maintaining a high suspicion of the disease, which would enable an early diagnosis and prompt treatment and decrease the risk for developing giant coronary aneurysms.

  11. Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma.

    Science.gov (United States)

    Oh, Ji Eun; Ohta, Takashi; Nonoguchi, Naosuke; Satomi, Kaishi; Capper, David; Pierscianek, Daniela; Sure, Ulrich; Vital, Anne; Paulus, Werner; Mittelbronn, Michel; Antonelli, Manila; Kleihues, Paul; Giangaspero, Felice; Ohgaki, Hiroko

    2016-07-01

    The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma. IDH mutations are the genetic hallmark of secondary glioblastomas. Gliosarcomas and giant cell glioblastomas are rare histological glioblastoma variants, which usually develop rapidly. We determined the genetic patterns of 36 gliosarcomas and 19 giant cell glioblastomas. IDH1 and IDH2 mutations were absent in all 36 gliosarcomas and in 18 of 19 giant cell glioblastomas analyzed, indicating that they are histological variants of primary glioblastoma. Furthermore, LOH 10q (88%) and TERT promoter mutations (83%) were frequent in gliosarcomas. Copy number profiling using the 450k methylome array in 5 gliosarcomas revealed CDKN2A homozygous deletion (3 cases), trisomy chromosome 7 (2 cases), and monosomy chromosome 10 (2 cases). Giant cell glioblastomas had LOH 10q in 50% and LOH 19q in 42% of cases. ATRX loss was detected immunohistochemically in 19% of giant cell glioblastomas, but absent in 17 gliosarcomas. These and previous results suggest that gliosarcomas are a variant of, and genetically similar to, primary glioblastomas, except for a lack of EGFR amplification, while giant cell glioblastoma occupies a hybrid position between primary and secondary glioblastomas. © 2015 International Society of Neuropathology.

  12. Resting site use of giant pandas in Wanglang Nature Reserve.

    Science.gov (United States)

    Kang, Dongwei; Wang, Xiaorong; Li, Junqing

    2017-10-23

    Little is known about the resting sites used by the giant panda (Ailuropoda melanoleuca), which restricts our understanding of their resting habits and limits conservation efforts. To enhance our understanding of resting site requirements and factors affecting the resting time of giant pandas, we investigated the characteristics of resting sites in the Wanglang Nature Reserve, Sichuan Province, China. The results indicated that the resting sites of giant pandas were characterised by a mean slope of 21°, mean nearest tree size of 53.75 cm, mean nearest shrub size of 2.82 cm, and mean nearest bamboo number of 56. We found that the resting sites were closer to bamboo than to trees and shrubs, suggesting that the resting site use of giant pandas is closely related to the presence of bamboo. Considering that giant pandas typically rest near a large-sized tree, protection of large trees in the forests is of considerable importance for the conservation of this species. Furthermore, slope was found to be an important factor affecting the resting time of giant pandas, as they tended to rest for a relatively longer time in sites with a smaller degree of slope.

  13. Loops and autonomy promote evolvability of ecosystem networks.

    Science.gov (United States)

    Luo, Jianxi

    2014-09-29

    The structure of ecological networks, in particular food webs, determines their ability to evolve further, i.e. evolvability. The knowledge about how food web evolvability is determined by the structures of diverse ecological networks can guide human interventions purposefully to either promote or limit evolvability of ecosystems. However, the focus of prior food web studies was on stability and robustness; little is known regarding the impact of ecological network structures on their evolvability. To correlate ecosystem structure and evolvability, we adopt the NK model originally from evolutionary biology to generate and assess the ruggedness of fitness landscapes of a wide spectrum of model food webs with gradual variation in the amount of feeding loops and link density. The variation in network structures is controlled by linkage rewiring. Our results show that more feeding loops and lower trophic link density, i.e. higher autonomy of species, of food webs increase the potential for the ecosystem to generate heritable variations with improved fitness. Our findings allow the prediction of the evolvability of actual food webs according to their network structures, and provide guidance to enhancing or controlling the evolvability of specific ecosystems.

  14. Protein structural modularity and robustness are associated with evolvability.

    Science.gov (United States)

    Rorick, Mary M; Wagner, Günter P

    2011-01-01

    Theory suggests that biological modularity and robustness allow for maintenance of fitness under mutational change, and when this change is adaptive, for evolvability. Empirical demonstrations that these traits promote evolvability in nature remain scant however. This is in part because modularity, robustness, and evolvability are difficult to define and measure in real biological systems. Here, we address whether structural modularity and/or robustness confer evolvability at the level of proteins by looking for associations between indices of protein structural modularity, structural robustness, and evolvability. We propose a novel index for protein structural modularity: the number of regular secondary structure elements (helices and strands) divided by the number of residues in the structure. We index protein evolvability as the proportion of sites with evidence of being under positive selection multiplied by the average rate of adaptive evolution at these sites, and we measure this as an average over a phylogeny of 25 mammalian species. We use contact density as an index of protein designability, and thus, structural robustness. We find that protein evolvability is positively associated with structural modularity as well as structural robustness and that the effect of structural modularity on evolvability is independent of the structural robustness index. We interpret these associations to be the result of reduced constraints on amino acid substitutions in highly modular and robust protein structures, which results in faster adaptation through natural selection.

  15. Adaptation of Escherichia coli to glucose promotes evolvability in lactose.

    Science.gov (United States)

    Phillips, Kelly N; Castillo, Gerardo; Wünsche, Andrea; Cooper, Tim F

    2016-02-01

    The selective history of a population can influence its subsequent evolution, an effect known as historical contingency. We previously observed that five of six replicate populations that were evolved in a glucose-limited environment for 2000 generations, then switched to lactose for 1000 generations, had higher fitness increases in lactose than populations started directly from the ancestor. To test if selection in glucose systematically increased lactose evolvability, we started 12 replay populations--six from a population subsample and six from a single randomly selected clone--from each of the six glucose-evolved founder populations. These replay populations and 18 ancestral populations were evolved for 1000 generations in a lactose-limited environment. We found that replay populations were initially slightly less fit in lactose than the ancestor, but were more evolvable, in that they increased in fitness at a faster rate and to higher levels. This result indicates that evolution in the glucose environment resulted in genetic changes that increased the potential of genotypes to adapt to lactose. Genome sequencing identified four genes--iclR, nadR, spoT, and rbs--that were mutated in most glucose-evolved clones and are candidates for mediating increased evolvability. Our results demonstrate that short-term selective costs during selection in one environment can lead to changes in evolvability that confer longer term benefits. © 2016 The Author(s). Evolution © 2016 The Society for the Study of Evolution.

  16. Giant Parotid Pleomorphic Adenoma Involving Parapharyngeal Space

    Directory of Open Access Journals (Sweden)

    Sukri Rahman

    2013-09-01

    Full Text Available AbstrakLatar belakang: Pleomorfik adenoma parotis merupakan tumor jinak kelenjar liur yang paling sering ditemukan, namun pleomorfik adenoma parotis yang sangat besar sehingga melibatkan ruang parafaring (RPF sangat jarang. Diagnosis ini sulit ditegakkan karena gejala klinisnya tidak khas. Penatalaksanaanya harus hati-hati mengingat banyak struktur vital yang beresiko mengalami trauma. Tujuan: Bagaimana menegakkan diagnosis dan penatalaksanaan pleomorfik adenoma parotis yang melibatkan RPF. Kasus: Seorang pasien perempuan 27 tahun ditegakkan diagnosis pleomorfik adenoma parotis kanan dengan melibatkan RPF. Terdapat pembengkakan pada leher yang bersifat asimtomatis dan gejala pendorongan faring dan laring yang menyebabkan disfonia, disfagia, dan defisit saraf kranial IX,X,XII. Penatalaksanaan: Pasien telah dilakukan operasi parotidektomi pendekatan transervikal–transparotid dengan preservasi arteri karotis eksterna dan saraf fasialis. Kesimpulan: Biopsi Aspirasi Jarum Halus (BAJAH dan radiologi merupakan pemeriksaan yang penting untuk menegakkan diagnosis. Penatalaksanaan pleomorfik adenoma parotis yang melibatkan RPF adalah bedah ekstirpasi komplit dengan beberapa pendekatan. .Kata kunci: tumor jinak kelenjar liur, pleomorfik adenoma, ruang parafaringAbstractBackground: Parotid pleomorphic adenoma is the most common benign salivary gland tumor, while giant parotid pleomorphic adenoma involving the parapharyngeal space (PPS is rare. It was difficult to diagnose because the clinical presentation of this tumor can be subtle. The management must be performed carefully due to anatomy relation to complex vital structure lead to traumatic injury highrisk. Purposes: How to make diagnosis and management parotid pleomorphic adenoma involving PPS. Case: A female 27 years old with diagnosis was giant parotid pleomorphic adenoma involving PPS. There was asymptomatic swelling of the neck and presence of pushing the pharynx and larynx medially causes

  17. NASA's Space Launch System: An Evolving Capability for Exploration An Evolving Capability for Exploration

    Science.gov (United States)

    Creech, Stephen D.; Crumbly, Christopher M.; Robinson, Kimerly F.

    2016-01-01

    A foundational capability for international human deep-space exploration, NASA's Space Launch System (SLS) vehicle represents a new spaceflight infrastructure asset, creating opportunities for mission profiles and space systems that cannot currently be executed. While the primary purpose of SLS, which is making rapid progress towards initial launch readiness in two years, will be to support NASA's Journey to Mars, discussions are already well underway regarding other potential utilization of the vehicle's unique capabilities. In its initial Block 1 configuration, capable of launching 70 metric tons (t) to low Earth orbit (LEO), SLS is capable of propelling the Orion crew vehicle to cislunar space, while also delivering small CubeSat-class spacecraft to deep-space destinations. With the addition of a more powerful upper stage, the Block 1B configuration of SLS will be able to deliver 105 t to LEO and enable more ambitious human missions into the proving ground of space. This configuration offers opportunities for launching co-manifested payloads with the Orion crew vehicle, and a class of secondary payloads, larger than today's CubeSats. Further upgrades to the vehicle, including advanced boosters, will evolve its performance to 130 t in its Block 2 configuration. Both Block 1B and Block 2 also offer the capability to carry 8.4- or 10-m payload fairings, larger than any contemporary launch vehicle. With unmatched mass-lift capability, payload volume, and C3, SLS not only enables spacecraft or mission designs currently impossible with contemporary EELVs, it also offers enhancing benefits, such as reduced risk, operational costs and/or complexity, shorter transit time to destination or launching large systems either monolithically or in fewer components. This paper will discuss both the performance and capabilities of Space Launch System as it evolves, and the current state of SLS utilization planning.

  18. Habitat Use and Selection by Giant Pandas.

    Directory of Open Access Journals (Sweden)

    Vanessa Hull

    Full Text Available Animals make choices about where to spend their time in complex and dynamic landscapes, choices that reveal information about their biology that in turn can be used to guide their conservation. Using GPS collars, we conducted a novel individual-based analysis of habitat use and selection by the elusive and endangered giant pandas (Ailuropoda melanoleuca. We constructed spatial autoregressive resource utilization functions (RUF to model the relationship between the pandas' utilization distributions and various habitat characteristics over a continuous space across seasons. Results reveal several new insights, including use of a broader range of habitat characteristics than previously understood for the species, particularly steep slopes and non-forest areas. We also used compositional analysis to analyze habitat selection (use with respect to availability of habitat types at two selection levels. Pandas selected against low terrain position and against the highest clumped forest at the at-home range level, but no significant factors were identified at the within-home range level. Our results have implications for modeling and managing the habitat of this endangered species by illustrating how individual pandas relate to habitat and make choices that differ from assumptions made in broad scale models. Our study also highlights the value of using a spatial autoregressive RUF approach on animal species for which a complete picture of individual-level habitat use and selection across space is otherwise lacking.

  19. Giant landslide deposits in northwest Argentina

    Energy Technology Data Exchange (ETDEWEB)

    Fauque, L.; Strecker, M.R.; Bloom, A.L.

    1985-01-01

    Giant Quaternary landslide deposits occur along mountain fronts in the structural transition zone between the high-angle reverse-fault-bounded Sierras Pampeanas and the low-angle thrust belt of the Sierras Subandinas. There are two modes of occurrence: (1) chaotic masses without distinct geometry, and (2) masses with distinct lobate geometry similar to glacial moraines. Type (1) deposits occur where the moving rock mass followed a narrow valley and blocked the drainage. Many of these caused subsequent formation of lakes and changed the sedimentation processes on pediments at the mountain fronts. In type (2) deposits, lateral and frontal ridges are up to 10 m higher than the interior parts; in some places pressure ridges within the lobes are well preserved. Type (2) deposits show reverse grading and were deposited on relatively smooth pediments or alluvial fans. The lobate geometry strongly suggests that type (2) deposits are a product of flowage and are debris stream or sturzstrom deposits (sense of Heim, 1932 and Hsu, 1975). All investigated deposits occur in areas of demonstrated Quaternary faulting and are interpreted as the result of tectonic movements, although structural inhomogeneities in the source area may have been a significant factor for some of the landslides. No datable materials have yet been found associated with the deposits.

  20. Giant comets and mass extinctions of life

    Science.gov (United States)

    Napier, W. M.

    2015-03-01

    I find evidence for clustering in age of well-dated impact craters over the last 500 Myr. At least nine impact episodes are identified, with durations whose upper limits are set by the dating accuracy of the craters. Their amplitudes and frequency are inconsistent with an origin in asteroid breakups or Oort cloud disturbances, but are consistent with the arrival and disintegration in near-Earth orbits of rare, giant comets, mainly in transit from the Centaur population into the Jupiter family and Encke regions. About 1 in 10 Centaurs in Chiron-like orbits enter Earth-crossing epochs, usually repeatedly, each such epoch being generally of a few thousand years' duration. On time-scales of geological interest, debris from their breakup may increase the mass of the near-Earth interplanetary environment by two or three orders of magnitude, yielding repeated episodes of bombardment and stratospheric dusting. I find a strong correlation between these bombardment episodes and major biostratigraphic and geological boundaries, and propose that episodes of extinction are most effectively driven by prolonged encounters with meteoroid streams during bombardment episodes. Possible mechanisms are discussed.

  1. Giant omphaloceles: surgical management and perinatal outcomes.

    Science.gov (United States)

    Akinkuotu, Adesola C; Sheikh, Fariha; Olutoye, Oluyinka O; Lee, Timothy C; Fernandes, Cariciolo J; Welty, Stephen E; Ayres, Nancy A; Cass, Darrell L

    2015-10-01

    The purpose of this study was to describe the current management and outcomes of infants with omphalocele. The medical records of all patients treated for omphalocele at a large children's hospital from January, 2003-February, 2014 were reviewed. Patients were classified as having an isolated omphalocele or omphalocele with minor or major associated anomalies. Prenatal data collected included fetal magnetic resonance imaging-based observed-to-expected total fetal lung volumes. Giant omphalocele (GO) was defined as >50% of liver in the omphalocele sac. Of 95 patients, 59 presented prenatally and had comprehensive fetal center evaluation. Of 82 live-born infants, 21 had chromosomal and 25 had major associated anomalies. No live-born baby with an isolated defect (n = 19) died, whereas mortality was 41% and 17% for those with major and minor anomalies, respectively (P = 0.006). Infants with major anomalies had significantly longer median length of intubation (36 versus 0 versus 0 d; P = 0.04) and hospital stay (157 versus 28.5 versus 18 d; P studies comparing delayed to early closure are needed to determine the optimal timing of repair. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Giant right groin lipoma mimicking inguinal hernia.

    Science.gov (United States)

    Gerych, Igor; Ivankiv, Taras; Ogurtsov, Oleksii; Kalynovych, Nazar

    2015-01-01

    Groin lipoma is a rare condition. Such localization may lead to erroneous interpretation of inguinal hernia diagnosis. In case of incorrect diagnosis, there is clinically high risk for development of intraoperative complications. The medical history of 70-year old female patient P., who has been hospitalized at Surgical Department No.1 of Danylo Halytsky Lviv National Medical University (Surgical Department of Lviv Regional Clinical Hospital), was processed retrospectively. Medical case history totals approximately 20 years. Examination in the right groin revealed a tumor falling to the right labia lip: soft, elastic, moderately painful, passive and active reduction into the abdominal cavity was impossible, and the "cough impulse" symptom was negative. CT correctly diagnosed giant right groin lipoma, which was intraoperatively confirmed. Lipoma in the groin may be treated as inguinal hernia. Thus, for the accurate verification of correct diagnosis, it is necessary to perform a follow-up examination involving computer tomography (CT) and nuclear magnetic resonance imaging (NMRI). Copyright © 2015. Published by Elsevier Ltd.

  3. Giant cell arteritis (cranial arteritis, polymyalgia rheumatica).

    Science.gov (United States)

    Mumenthaler, M

    1978-08-25

    Giant cell arteritis, which is probably due to disturbed immune mechanisms, has a spectrum of clinical symptoms in elderly people. In nearly all cases such general signs as loss of appetite, loss of weight and fever are present. The sedimentation rate is almost without exception about 100 mm in the first hour. The two most frequent and typical clinical syndromes are polymyalgia rheumatica and cranial arteritis. The polymyalgia rheumatica is characterized by periarticular pain which is mostly symmetrical and accentuated in the shoulder girdle. Increasingly severe temporal headache and ocular distrubances are found with cranial arteritis in more than 50% of cases. A combination of both diseases is frequent. Other arterial branches are rarely involved. The course of the disease is over a period of 1 1/2 to 2 years. Treatment with corticosteroids is indicated mainly because of the severe ocular complications with blindness. It should begin immediately, be intensive and last over a long period. Regular followup is necessary over several years in order to avoid relapses.

  4. Giant Galaxy Messier 87 finally sized up

    Science.gov (United States)

    2009-05-01

    Using ESO's Very Large Telescope, astronomers have succeeded in measuring the size of giant galaxy Messier 87 and were surprised to find that its outer parts have been stripped away by still unknown effects. The galaxy also appears to be on a collision course with another giant galaxy in this very dynamic cluster. ESO PR Photo 19a/09 The Intercluster Light ESO PR Photo 19b/09 Intergalactic Planetary Nebulae ESO PR Photo 19c/09 The Virgo Cluster The new observations reveal that Messier 87's halo of stars has been cut short, with a diameter of about a million light-years, significantly smaller than expected, despite being about three times the extent of the halo surrounding our Milky Way [1]. Beyond this zone only few intergalactic stars are seen. "This is an unexpected result," says co-author Ortwin Gerhard. "Numerical models predict that the halo around Messier 87 should be several times larger than our observations have revealed. Clearly, something must have cut the halo off early on." The team used FLAMES, the super-efficient spectrograph at ESO's Very Large Telescope at the Paranal Observatory in Chile, to make ultra-precise measurements of a host of planetary nebulae in the outskirts of Messier 87 and in the intergalactic space within the Virgo Cluster of galaxies, to which Messier 87 belongs. FLAMES can simultaneously take spectra many sources, spread over an area of the sky about the size of the Moon. The new result is quite an achievement. The observed light from a planetary nebula in the Virgo Cluster is as faint as that from a 30-Watt light bulb at a distance of about 6 million kilometres (about 15 times the Earth-Moon distance). Furthermore, planetary nebulae are thinly spread through the cluster, so even FLAMES's wide field of view could only capture a few tens of nebulae at a time. "It is a little bit like looking for a needle in a haystack, but in the dark", says team member Magda Arnaboldi. "The FLAMES spectrograph on the VLT was the best instrument

  5. The Giant Magellan Telescope adaptive optics program

    Science.gov (United States)

    Bouchez, Antonin H.; Acton, D. Scott; Agapito, Guido; Arcidiacono, Carmelo; Bennet, Francis; Biliotti, Valdemaro; Bonaglia, Marco; Briguglio, Runa; Brusa-Zappellini, Guido; Busoni, Lorenzo; Carbonaro, Luca; Codona, Johanan L.; Conan, Rodolphe; Connors, Thomas; Durney, Oliver; Espeland, Brady; Esposito, Simone; Fini, Luca; Gardhouse, Rusty; Gauron, Thomas M.; Hart, Michael; Hinz, Philip M.; Kanneganti, Srikrishna; Kibblewhite, Edward J.; Knox, Russell P.; McLeod, Brian A.; McMahon, Thomas; Montoya, Manny; Norton, Timothy J.; Ordway, Mark P.; d'Orgeville, Celine; Parcell, Simon; Piatrou, Piotr K.; Pinna, Enrico; Price, Ian; Puglisi, Alfio; Quiros-Pacheco, Fernando; Riccardi, Armando; Roll, John B.; Trancho, Gelys; Uhlendorf, Kristina; Vaitheeswaran, Vidhya; van Dam, Marcos A.; Weaver, David; Xompero, Marco

    2012-07-01

    The Giant Magellan Telescope adaptive optics system will be an integral part of the telescope, providing laser guide star generation, wavefront sensing, and wavefront correction to most of the currently envisioned instruments. The system will provide three observing modes: Natural Guidestar AO (NGSAO), Laser Tomography AO (LTAO), and Ground Layer AO (GLAO). Every AO observing mode will use the telescope’s segmented adaptive secondary mirror to deliver a corrected beam directly to the instruments. High-order wavefront sensing for the NGSAO and LTAO modes is provided by a set of wavefront sensors replicated for each instrument and fed by visible light reflected off the cryostat window. An infrared natural guidestar wavefront sensor with open-loop AO correction is also required to sense tip-tilt, focus, segment piston, and dynamic calibration errors in the LTAO mode. GLAO mode wavefront sensing is provided by laser guidestars over a ~5 arcminute field of view, and natural guidestars over wider fields. A laser guidestar facility will project 120 W of 589 nm laser light in 6 beacons from the periphery of the primary mirror. An off-axis phasing camera and primary and secondary mirror metrology systems will ensure that the telescope optics remain phased. We describe the system requirements, overall architecture, and innovative solutions found to the challenges presented by high-order AO on a segmented extremely large telescope. Further details may be found in specific papers on each of the observing modes and major subsystems.

  6. A strategy for treatment of giant omphalocele.

    Science.gov (United States)

    Sönmez, Kaan; Onal, Esra; Karabulut, Ramazan; Turan, Ozden; Türkyilmaz, Zafer; Hirfanoğlu, Ibrahim; Kapisiz, Alparslan; Başaklar, Abdullah C

    2010-08-01

    The management of giant omphalocele (GO) presents a major challenge to pediatric surgeons. Current treatment modalities may result in wound infection, fascial separation, and abdominal domain loss. We report a GO infant who required a delayed closure and was managed using sterile incision drape and polypropylene mesh. A 3080 g full-term female infant was born with a GO. The skin was dissected from the fascia circumferentially without opening the amniotic sac and the peritoneum. Subsequently, two polypropylene meshes of 10 x 10 cm in diameter were sutured to each other. Inner surface of the mesh silo was covered with sterile incision drape. This texture was sutured to the fascial margin. Then, the skin was sutured to the mesh and the silo was closed from the side and above. On the 4th day the reduction was started using thick sutures without anesthesia. This procedure was repeated on every 3rd day. When it came closer to the skin margins, constriction was performed using right angle clamps, each time placed 2 cm proximally to the previous sutures in a circular manner. Silo was removed easily and the skin, subcutaneous layers, and fascia were then approximated on the 42nd day. The postoperative course was uneventful and the infant was well with left inguinal hernia repaired in the 3rd month. The method we used can be performed at bedside and without the application of anesthesia, but should be tried on more patients to determine its effect.

  7. Giant Tunneling Magnetoresistance (TMR) in Graphene Patches

    Science.gov (United States)

    Agapito, Luis; Kioussis, Nicholas

    2010-03-01

    Graphene-based field effect devices based on graphene flakes and nanoislands have attracted a great deal of attention due to their unique physical properties and potential for nanoelectronic applications. The emergence of magnetism[1,2] in nanometer graphene patches terminated by zigzag edges along with the low intrinsic spin-orbit interaction opens a new research venue for spintronics, such as tunneling magnetoresistance, spin filter, and quantum computing. We have employed density functional theory and the nonequilibrium Green's functions approach to study the charge and spin transport in tunnel junctions comprising of one and two zigzag-terminated graphene triangular flakes connected to reconstructed zigzag-terminated graphene ribbons. We will present results of (1) the interplay between gate voltage and its incidence on the selection of the filtered spin channel and (2) the effect of the relative orientation of the magnetizations of the two graphene nanoflakes on the transport of the tunnel junctions. The calculations demonstrate the possibility of engineering such graphene patches as magnetic tunneling junctions that exhibit giant TMR. [1] J. Fernandez-Rossier et al., Physical Review Letters 99 (2007). [2] W. L. Wang et al., Nano Letters 8, 241 (2008).

  8. The Giant Radio Array for Neutrino Detection

    Directory of Open Access Journals (Sweden)

    Martineau-Huynh Olivier

    2017-01-01

    Full Text Available The Giant Radio Array for Neutrino Detection (GRAND is a planned array of ~ 2·105 radio antennas deployed over ~ 200 000 km2 in a mountainous site. It aims primarly at detecting high-energy neutrinos via the observation of extensive air showers induced by the decay in the atmosphere of taus produced by the interaction of cosmic neutrinos under the Earth surface. GRAND aims at reaching a neutrino sensitivity of 5 · 10−11 E−2 GeV−1 cm−2 s−1 sr−1 above 3 · 1016 eV. This ensures the detection of cosmogenic neutrinos in the most pessimistic source models, and ~50 events per year are expected for the standard models. The instrument will also detect UHECRs and possibly FRBs. Here we show how our preliminary design should enable us to reach our sensitivity goals, and discuss the steps to be taken to achieve GRAND, while the compelling science case for GRAND is discussed in more details in [1].

  9. Self-Evolvable Systems Machine Learning in Social Media

    CERN Document Server

    Iordache, Octavian

    2012-01-01

    This monograph presents key method to successfully manage the growing  complexity of systems  where conventional engineering and scientific methodologies and technologies based on learning and adaptability come to their limits and new ways are nowadays required. The transition from adaptable to evolvable and finally to self-evolvable systems is highlighted, self-properties such as self-organization, self-configuration, and self-repairing are introduced and challenges and limitations of the self-evolvable engineering systems are evaluated.

  10. Diffuse-type giant cell tumor of the subcutaneous thigh

    Energy Technology Data Exchange (ETDEWEB)

    Sanghvi, D.A. [KEM Hospital, Department of Radiology, Parel, Mumbai (India); Purandare, N.C. [Tata Memorial Hospital, Bio Imaging Unit, Parel, Mumbai (India); Jambhekar, N.A.; Agarwal, A. [Tata Memorial Hospital, Department of Pathology, Parel, Mumbai (India); Agarwal, M.G. [Tata Memorial Hospital, Bone and Soft Tissue Unit, Parel, Mumbai (India)

    2007-04-15

    Diffuse-type giant cell tumor is an extra-articular form of pigmented villonodular synovitis. The localized form of this lesion (tenosynovial giant cell tumor) is frequent, representing the most common subset arising from the synovium of a joint, bursa or tendon sheath, with 85% of cases occurring in the fingers. The less frequent diffuse-type giant cell tumors are commonly located in the periarticular soft tissues, but on rare occasions these lesions can be purely intramuscular or subcutaneous We report the case of a 26-year-old female with diffuse-type giant cell tumor of the subcutaneous thigh, remote from a joint, bursa or tendon sheath. A review of the literature did not reveal any similar description of a diffuse-type giant cell tumor completely within the subcutaneous thigh, remote from a joint, bursa or tendon sheath. These lesions were initially regarded as inflammatory or reactive processes, but since the identification of clonal abnormalities in these patients, and in view of their capacity for autonomous growth, they are now widely considered to represent benign neoplasms. (orig.)

  11. The Lushan earthquake and the giant panda: impacts and conservation.

    Science.gov (United States)

    Zhang, Zejun; Yuan, Shibin; Qi, Dunwu; Zhang, Mingchun

    2014-06-01

    Earthquakes not only result in a great loss of human life and property, but also have profound effects on the Earth's biodiversity. The Lushan earthquake occurred on 20 Apr 2013, with a magnitude of 7.0 and an intensity of 9.0 degrees. A distance of 17.0 km from its epicenter to the nearest distribution site of giant pandas recorded in the Third National Survey was determined. Making use of research on the Wenchuan earthquake (with a magnitude of 8.0), which occurred approximately 5 years ago, we briefly analyze the impacts of the Lushan earthquake on giant pandas and their habitat. An earthquake may interrupt ongoing behaviors of giant pandas and may also cause injury or death. In addition, an earthquake can damage conservation facilities for pandas, and result in further habitat fragmentation and degradation. However, from a historical point of view, the impacts of human activities on giant pandas and their habitat may, in fact, far outweigh those of natural disasters such as earthquakes. Measures taken to promote habitat restoration and conservation network reconstruction in earthquake-affected areas should be based on requirements of giant pandas, not those of humans. © 2013 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

  12. Null-wave giant gravitons from thermal spinning brane probes

    Science.gov (United States)

    Armas, Jay; Obers, Niels A.; Pedersen, Andreas Vigand

    2013-10-01

    We construct and analyze thermal spinning giant gravitons in type II/M-theory based on spherically wrapped black branes, using the method of thermal probe branes originating from the blackfold approach. These solutions generalize in different directions recent work in which the case of thermal (non-spinning) D3-brane giant gravitons was considered, and reveal a rich phase structure with various new properties. First of all, we extend the construction to M-theory, by constructing thermal giant graviton solutions using spherically wrapped M2- and M5-branes. More importantly, we switch on new quantum numbers, namely internal spins on the sphere, which are not present in the usual extremal limit for which the brane world volume stress tensor is Lorentz invariant. We examine the effect of this new type of excitation and in particular analyze the physical quantities in various regimes, including that of small temperatures as well as low/high spin. As a byproduct we find new stationary dipole-charged black hole solutions in AdS m × S n backgrounds of type II/M-theory. We finally show, via a double scaling extremal limit, that our spinning thermal giant graviton solutions lead to a novel null-wave zero-temperature giant graviton solution with a BPS spectrum, which does not have an analogue in terms of the conventional weakly coupled world volume theory.

  13. Observationally Constraining Gas Giant Composition via Their Host Star Abundances

    Science.gov (United States)

    Teske, Johanna; Thorngren, Daniel; Fortney, Jonathan

    2018-01-01

    While the photospheric abundances of the Sun match many rock-forming elemental abundances in the Earth to within 10 mol%, as well as in Mars, the Moon, and meteorites, the Solar System giant planets are of distinctly non-stellar composition — Jupiter's bulk metallicity (inferred from its bulk density, measured from spacecraft data) is ∼ x5-10 solar, and Saturn is ∼ x10-20 solar. This knowledge has led to dramatic advances in understanding models of core accretion, which now match the heavy element enrichment of each of the Solar System's giant planets. However, we have thus far lacked similar data for exoplanets to use as a check for formation and composition models over a much larger parameter space. Here we present a study of the host stars of a sample of cool transiting gas giants with measured bulk metal fractions (as in Thorngren et al. 2016) to better constrain the relation Zplanet/Zstar — giant exoplanet metal enrichment relative to the host star. We add a new dimension of chemical variation, measuring C, O, Mg, Si, Ni, and well as Fe (on which previous Zplanet/Zstar calculations were based). Our analysis provides the best constraints to date on giant exoplanet interior composition and how this relates to formation environment, and make testable predictions for JWST observations of exoplanet atmospheres.

  14. The pathogenesis of giant cell arteritis: morphological aspects.

    Science.gov (United States)

    Nordborg, C; Nordborg, E; Petursdottir, V

    2000-01-01

    The light-microscopic, electron-microscopic and immunocytochemical characteristics of giant cell arteritis (GCA) have been investigated in a number of studies on temporal arteries. Arterial atrophy and calcification of the internal elastic membrane appear to be prerequisites for the evolution of the inflammatory process. Foreign body giant cells form close to calcifications, apparently without connection with other inflammatory cells and probably by the fusion of modified vascular smooth muscle cells. The foreign body giant cells attack the calcifications. Lymphocytes accumulate around them and may be found in pockets in their cell surface. This focal reaction is found in atrophic, calcified arterial segments in a minority of inflamed temporal artery biopsies. More commonly seen is a diffuse mononuclear attack of the vessel wall in atrophic as well as non-atrophic segments which leads to severe arterial dilatation. Langhans giant cells form by the fusion of macrophages in the diffuse inflammatory infiltrate. The fact that the diffusely inflamed arteries are markedly widened compared to the focally inflamed vessels suggests that the inflammatory process starts as a focal foreign body giant cell reaction directed at calcifications which in turn initiates a more diffuse and widespread inflammation.

  15. Radiological features of childhood giant cavernous malformations

    Energy Technology Data Exchange (ETDEWEB)

    Ozgen, Burce; Senocak, Efsun; Oguz, Kader K. [Hacettepe University, Department of Radiology, Faculty of Medicine, Ankara (Turkey); Soylemezoglu, Figen [Hacettepe University, Department of Pathology, School of Medicine, Ankara (Turkey); Akalan, Nejat [Hacettepe University, Department of Neurosurgery, School of Medicine, Ankara (Turkey)

    2011-04-15

    Giant cavernous malformations (GCM) are very large, low-flow vascular malformations, which usually have atypical imaging features and are commonly misdiagnosed preoperatively as neoplasms or vascular malformations. These lesions have mostly been reported in children. As cavernomas show different features in children compared to adults, we evaluated the imaging features of pediatric GCMs in order to help in the preoperative diagnosis of these malformations. Brain MR studies of nine children (mean age of 4 years; 8 months-9 years) with biopsy-proven GCM were retrospectively evaluated. We defined GCMs as cavernomas of {>=}4 cm. Lesions were evaluated regarding their size, location, signal characteristics, general appearance (uni/multilocular) as well as regarding the presence of mass effect, edema, and fluid-fluid levels and were classified according to the Mottolese classification of pediatric cavernomas. Lesion locations were parietal (n = 5), frontal (n = 2), temporal, and intraventricular. Seven lesions were in the periventricular region (with five in the periatrial region). Six patients had T1 hyperintense multilobulated lesions with ''bubbles of blood'' appearance and three patients had heterogeneous lesions with reticular core. All lesions had mass effect, edema (marked in four cases), and peripheral hemosiderin rim. Fluid-fluid levels were also common (n = 7). Most of our lesions (six of nine) were classified as type IIIA, two as type IIIC, and one as type IA. In children, a GCM should be considered in case of very large hemorrhagic intra-axial mass with ''bubbles of blood'' multicystic appearance, surrounding hemosiderin ring, fluid-fluid levels, and accompanying edema-mass effect, especially in the periatrial location. (orig.)

  16. A New Survey for Giant Arcs

    Energy Technology Data Exchange (ETDEWEB)

    Hennawi, Joseph F.; Gladders, Michael D.; Oguri, Masamune; Dalal, Neal; Koester, Benjamin; Natarajan, Priyamvada; Strauss, Michael A.; Inada, Naohisa; Kayo, Issha; Lin,; Lampeitl, Hubert; Annis, James; Bahcall, Neta A.; Schneider, Donald P.

    2006-11-15

    We report on the first results of an imaging survey to detect strong gravitational lensing targeting the richest clusters selected from the photometric data of the Sloan Digital Sky Survey (SDSS) with follow-up deep imaging observations from the Wisconsin Indiana Yale NOAO (WIYN) 3.5m telescope and the University of Hawaii 88-inch telescope (UH88). The clusters are selected from an area of 8000 deg{sup 2} using the Red Cluster Sequence technique and span the redshift range 0.1 {approx}< z {approx}< 0.6, corresponding to a comoving cosmological volume of {approx} 2Gpc{sup 3}. Our imaging survey thus targets a volume more than an order of magnitude larger than any previous search. A total of 240 clusters were imaged of which 141 had sub-arcsecond image quality. Our survey has uncovered 16 new lensing clusters with definite giant arcs, an additional 12 systems for which the lensing interpretation is very likely, and 9 possible lenses which contain shorter arclets or candidate arcs which are less certain and will require further observations to confirm their lensing origin. The number of new cluster lenses detected in this survey is likely > 30. Among these new systems are several of the most dramatic examples of strong gravitational lensing ever discovered with multiple bright arcs at large angular separation. These will likely become 'poster-child' gravitational lenses similar to Abell 1689 and CL0024+1654. The new lenses discovered in this survey will enable future systematic studies of the statistics of strong lensing and its implications for cosmology and our structure formation paradigm.

  17. Adapting Morphology to Multiple Tasks in Evolved Virtual Creatures

    DEFF Research Database (Denmark)

    Lessin, Dan; Fussell, Don; Miikkulainen, Risto

    2014-01-01

    The ESP method for evolving virtual creatures (Lessin et al., 2013) consisted of an encapsulation mechanism to preserve learned skills, a human-designed syllabus to build higherlevel skills by combining lower-level skills systematically, and a pandemonium mechanism to resolve conflicts between...... encapsulated skills in a single creature’s brain. Previous work with ESP showed that it is possible to evolve much more complex behavior than before, even when fundamental morphology (i.e., skeletal segments and joints) was evolved only for the first skill. This paper introduces a more general form of ESP...... in which full morphological development can continue beyond the first skill, allowing creatures to adapt their morphology to multiple tasks. This extension increases the variety and quality of evolved creature results significantly, while maintaining the original ESP system’s ability to incrementally...

  18. Orthogonally Evolved AI to Improve Difficulty Adjustment in Video Games

    DEFF Research Database (Denmark)

    Hintze, Arend; Olson, Randal; Lehman, Joel Anthony

    2016-01-01

    (i.e. agents subject to fewer generations of evolution) make for easier opponents, while highly-evolved agents are more challenging to overcome. In this publication we test a new approach for difficulty adjustment in games: orthogonally evolved AI, where the player receives support from collaborating...... agents that are co-evolved with opponent agents (where collaborators and opponents have orthogonal incentives). The advantage is that game difficulty can be adjusted more granularly by manipulating two independent axes: by having more or less adept collaborators, and by having more or less adept...... opponents. Furthermore, human interaction can modulate (and be informed by) the performance and behavior of collaborating agents. In this way, orthogonally evolved AI both facilitates smoother difficulty adjustment and enables new game experiences....

  19. Evolving the Evolving: Territory, Place and Rewilding in the California Delta

    Directory of Open Access Journals (Sweden)

    Brett Milligan

    2017-10-01

    Full Text Available Current planning and legislation in California’s Sacramento-San Joaquin Delta call for the large-scale ecological restoration of aquatic and terrestrial habitats. These ecological mandates have emerged in response to the region’s infrastructural transformation and the Delta’s predominant use as the central logistical hub in the state’s vast water conveyance network. Restoration is an attempt to recover what was externalized by the logic and abstractions of this logistical infrastructure. However, based on findings from our research, which examined how people are using restored and naturalized landscapes in the Delta and how these landscapes are currently planned for, we argue that as mitigatory response, restoration planning continues some of the same spatial abstractions and inequities by failing to account for the Delta as an urbanized, cultural and unique place. In interpreting how these conditions have come to be, we give attention to a pluralistic landscape approach and a coevolutionary reading of planning, policy, science and landscapes to discuss the conservation challenges presented by “Delta as an Evolving Place”. We suggest that for rewilding efforts to be successful in the Delta, a range of proactive, opportunistic, grounded and participatory tactics will be required to shift towards a more socio-ecological approach.

  20. (N+1)-dimensional Lorentzian evolving wormholes supported by polytropic matter

    Energy Technology Data Exchange (ETDEWEB)

    Cataldo, Mauricio [Universidad del Bio-Bio, Departamento de Fisica, Facultad de Ciencias, Concepcion (Chile); Arostica, Fernanda; Bahamonde, Sebastian [Universidad de Concepcion, Departamento de Fisica, Concepcion (Chile)

    2013-08-15

    In this paper we study (N+1)-dimensional evolving wormholes supported by energy satisfying a polytropic equation of state. The considered evolving wormhole models are described by a constant redshift function and generalizes the standard flat Friedmann-Robertson-Walker spacetime. The polytropic equation of state allows us to consider in (3+1)-dimensions generalizations of the phantom energy and the generalized Chaplygin gas sources. (orig.)