WorldWideScience

Sample records for event periods due

  1. Causes and circumstances of damage to people in Calabria (Italy) due to hydrogeological events in the period 1980-2014

    Science.gov (United States)

    Aceto, Luigi; Pasqua, A. Aurora; Petrucci, Olga

    2017-04-01

    Damaging Hydrogeological Events (DHE) can be defined as rainy periods during which landslides and floods can damage people. We investigates the effects of DHE on people in Calabria (southern Italy) ,in the period 1980-2014, using data coming from the systematic survey of regional daily newspapers. Data about "fatalities", people "injured" and people "involved" (not killed neither hurt) are stored in the database named PEOPLE, made of five sections: 1) event identification, 2) victim identification, 3) type of victim's involvement, 4) victim-event interaction, and 5) effects on victim. The outcomes highlight vulnerability factors related to gender and age: males were killed more frequently (75%) than females (25%), and fatalities were older (average age 49 years) than injured (40.1 years) and involved people (40.5 years). The average age of females killed (67.5 years), injured (43.4 years) and involved (44.6 years) were higher than the same values assessed for males, maybe indicating that younger females tend to be more cautious than coetaneous males, while older females show an intrinsic greater vulnerability. Involved people were younger than injured and fatalities, perhaps because younger people showed greater promptness to react in dangerous situations. In the study region, floods caused more fatalities (67.9%), injured (55%) and involved people (55.3%) than landslides. Fatalities and injured mainly occurred outdoor, especially along roads, and the most dangerous dynamic seems to be dragged by flood, causing the majority of fatalities. The present work is the progression of the described research, and it has been carried out by enlarging the database to a 34-year period, from 1980 to 2014. The aim is to validate the conclusions drawn for the 2000-2014 period and to investigate if and how the gender and age vulnerability factors of Calabrian people have been changing throughout the study period.

  2. Predictions of Resuspension of Highway Detention Pond Deposits in Interrain Event Periods due to Wind-Induced Currents and Waves

    DEFF Research Database (Denmark)

    Bentzen, Thomas Ruby; Larsen, Torben; Rasmussen, Michael R.

    2009-01-01

    The paper presents a numerical study of resuspension of deposits from highway detention ponds based on a previous experimental study. The resuspension process is evaluated in dry weather periods with baseflow/infiltration flow through the ponds only. The resuspension is caused by the bed-shear st...

  3. Periodic fluctuations in deep water formation due to sea ice

    Science.gov (United States)

    Saha, R.

    2012-12-01

    During the last ice age, several abrupt warming events took place, known as Dansgaard-Oeschger (D-O) events. Their effects were felt globally, although the North Atlantic experienced the largest temperature increase. The leading hypothesis to explain their occurrence postulates that the warming was caused by abrupt disruptions of the North Atlantic Current due to meltwater discharge from destabilized ice sheets (Heinrich events). However, the number of warming events outnumber the those of ice-sheet collapse. Thus, the majority of D-O events are not attributed to surface freshwater anomalies, and the underlying mechanism behind their occurrence remain unexplained. Using a simple dynamical model of sea ice and an overturning circulation, I show the existence of self-sustained relaxation oscillations in the overturning circulation. The insulating effect of sea ice is shown to paradoxically lead to a net loss of heat from the top layer of the polar ocean when sea ice retreats. Repeated heat loss results in a denser top layer and a destabilized water column, which triggers convection. The convective state pulls the system out of its preferred mode of circulation, setting up relaxation oscillations. The period of oscillations in this case is linked to the geometry of the ocean basin, if solar forcing is assumed to remain constant. If appropriate glacial freshwater forcing is applied to the model, a pattern of oscillation is produced that bears remarkable similarity to the observed fluctuations in North Atlantic climate between 50,000 and 30,000 years before present.; Comparison of NGRIP δ 18-O (proxy for near surface air temperature) between 50,000 and 30,000 years before present, showing Bond cycles (left) with the model output when forced with appropriate glacial freshwater forcing (right).

  4. Thromboembolic Events in the Perioperative Period

    NARCIS (Netherlands)

    F. van Lier (Felix)

    2011-01-01

    textabstractThe first chapter provides an overview of cardiovascular risk identification and modification in the perioperative period. In this chapter the identification of patients at risk using various risk models and biomarkers is described. Noninvasive and invasive preoperative (stress) testing

  5. [Period-tripling in Multiscale Physical and Biological Events].

    Science.gov (United States)

    Bondar, A T; Fedorov, M V; Kolombet, V A

    2015-01-01

    A recent paper by S.J. Puetz et al. (Chaos, Solitons -& Fractals, v. 62-63, p. 55, 2014) described a fundamental period-tripled model. It involves periods of different astronomical (quasars, Sun), geophysical (geomagnetic, climatic, volcanic) and some biological processes. This work contains statistics for sixteen pairs of a period-tripled sequence. These periods range from -50 years to 1.5 billion years and no signs of the timescale limitations are found. We believe that the universal scope of the fundamental period-tripled model can be used for the development of new methodology of research data analysis: the main idea is that the spectrum of the periods of the studied event should be tested for the similarity with the spectrum of fundamental period-tripling pattern (because of the fundamental nature of the period-tripled model). Using this method, in this study we complement an already described period-tripled model with periods of human memory performance ranging from one minute to one month also adding seven relevant periods/frequencies of the period-tripled model in the range of human hearing. We make a conclusion that these characteristic frequencies may form the basis for music and singing phenomena. The new methodology is particularly appropriate for being applied in medicine and engineering.

  6. Periods of Excess Energy in Extreme Weather Events

    Directory of Open Access Journals (Sweden)

    Igor G. Zurbenko

    2013-01-01

    Full Text Available The reconstruction of periodic signals that are embedded in noise is a very important task in many applications. This already difficult task is even more complex when some observations are missed or some are presented irregularly in time. Kolmogorov-Zurbenko (KZ filtration, a well-developed method, offers a solution to this problem. One section of this paper provides examples of very precise reconstructions of multiple periodic signals covered with high level noise, noise levels that make those signals invisible within the original data. The ability to reconstruct signals from noisy data is applied to the numerical reconstruction of tidal waves in atmospheric pressure. The existence of such waves was proved by well-known naturalist Chapman, but due to the high synoptic fluctuation in atmospheric pressure he was unable to numerically reproduce the waves. Reconstruction of the atmospheric tidal waves reveals a potential intensification on wind speed during hurricanes, which could increase the danger imposed by hurricanes. Due to the periodic structure of the atmospheric tidal wave, it is predictable in time and space, which is important information for the prediction of excess force in developing hurricanes.

  7. Spinal muscular atrophy due to double gene conversion event.

    Science.gov (United States)

    Maamouri, Wiéme; Hammer, Monia Benhamed; Bouhlel, Yosr; Souilem, Sihem; Khmiri, Najla; Nehdi, Houda; Hentati, Fayçal; Amouri, Rim

    2011-02-01

    Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by degeneration of the anterior horn cells of the spinal cord. The survival motor neuron (SMN) gene has been identified as an SMA-determining gene. SMN exists as two copies in 5q13, and deletions in exons 7 and 8 of the telomeric copy (SMN(T)) occur in 95% of patients, regardless of disease severity. In a minority of patients, exon 7 but not exon 8 of SMN(T) appears deleted. We now report a patient with typical features of SMA type II who carried homozygous deletions of SMN(T) exon 7 and centromeric SMN (SMN(C)) exon 8 but retained SMN(T) exon 8 and SMN(C) exon 7. Sequence analysis demonstrated that SMN(C) exon 7 was adjacent to SMN(T) exon 8 on both SMN copies, indicating a double conversion. We confirm that sequence conversion is a common event in SMA and is associated with the milder form of the disease. The severity, however, can be modified in either positive or negative direction by other factors.

  8. Sediment reallocations due to erosive rainfall events in the Three Gorges Reservoir Area, Central China

    Science.gov (United States)

    Stumpf, Felix; Goebes, Philipp; Schmidt, Karsten; Schindewolf, Marcus; Schönbrodt-Stitt, Sarah; Wadoux, Alexandre; Xiang, Wei; Scholten, Thomas

    2017-04-01

    Soil erosion by water outlines a major threat to the Three Gorges Reservoir Area in China. A detailed assessment of soil conservation measures requires a tool that spatially identifies sediment reallocations due to rainfall-runoff events in catchments. We applied EROSION 3D as a physically based soil erosion and deposition model in a small mountainous catchment. Generally, we aim to provide a methodological frame that facilitates the model parametrization in a data scarce environment and to identify sediment sources and deposits. We used digital soil mapping techniques to generate spatially distributed soil property information for parametrization. For model calibration and validation, we continuously monitored the catchment on rainfall, runoff and sediment yield for a period of 12 months. The model performed well for large events (sediment yield>1 Mg) with an averaged individual model error of 7.5%, while small events showed an average error of 36.2%. We focused on the large events to evaluate reallocation patterns. Erosion occurred in 11.1% of the study area with an average erosion rate of 49.9Mgha 1. Erosion mainly occurred on crop rotation areas with a spatial proportion of 69.2% for 'corn-rapeseed' and 69.1% for 'potato-cabbage'. Deposition occurred on 11.0%. Forested areas (9.7%), infrastructure (41.0%), cropland (corn-rapeseed: 13.6%, potatocabbage: 11.3%) and grassland (18.4%) were affected by deposition. Because the vast majority of annual sediment yields (80.3%) were associated to a few large erosive events, the modelling approach provides a useful tool to spatially assess soil erosion control and conservation measures.

  9. Mitigation of Disasters Due to Severe Climate Events: from Policy to Practice,the West African Coastal Region Experience

    Science.gov (United States)

    Ediang, Okuku

    2016-07-01

    The distributive pattern of disaster due to severe climate events over the coast of West Africa especially Nigeria was examined using yearly mean disaster due to severe climatic events for the period of 30 years (1981-2010) from the marine stations in the coastal region of Nigeria. Graphical and isohyetal analyses were used to look into the patter of severe weather events over the area considered and to see if the severe weather events is increasing or not in the coast of West Africa especially the Nigerian coast and how to mitigate ,were policy relating to severe weather events are discussed. The paper conclude that due to the nature of coast of West Africa and Nigeria in particular, it enjoys longer severe weather events season than dry during the wet season, it is common to observe periods of enhanced or suppressed convective activity to persist over the wide areas for somedays. This paper also contributes to the wealth of knowledge already existing on Indigenous people play major roles in preserving the ecosystem especially during severe weather events . This has resulted in the recent calls for the integration of indigenous knowledge systems into global knowledge system strategies. Until now, integrating local knowledge systems into severe weather events and climate change concerns is not a completely new idea. A comprehensive review of literature using electronic and non-electronic databases formed the methodology. The paper conclude also by drawing the attention that by targeting Promoting indigenous people's participation in severe weather events and climate change issues is an important initiative towards adaptation and sustainable development in Africa and around the world. It is increasingly realized that the global knowledge system has dominated research, policies and programmes that address current severe weather events and climate change's challenges,mitigation and adaptation strategies.

  10. Pulmonary Arterial Capacitance Predicts Cardiac Events in Pulmonary Hypertension Due to Left Heart Disease.

    Directory of Open Access Journals (Sweden)

    Koichi Sugimoto

    Full Text Available Although pulmonary hypertension due to left heart disease (LHD-PH accounts for the largest proportion of pulmonary hypertension, few reports on the epidemiological analysis of LHD-PH exist. Recently, pulmonary arterial capacitance (PAC has attracted attention as a possible factor of right ventricular afterload along with pulmonary vascular resistance. We therefore investigated the clinical significance of PAC in LHD-PH.The subject consisted of 252 LHD-PH patients (145 men, mean age 63.4 ± 14.7 years diagnosed by right heart catheterization. PAC was estimated by the ratio between stroke volume and pulmonary arterial pulse pressure. Patients were classified into four groups according to the PAC (1st quartile was 0.74 to 1.76 ml/mmHg, the 2nd quartile 1.77 to 2.53 ml/mmHg, the 3rd quartile 2.54 to 3.59 ml/mmHg, and the 4th quartile 3.61 to 12.14 ml/mmHg. The end-points were defined as rehospitalization due to worsening heart failure and/or cardiac death. The Cox proportional hazard regression model was used to determine what variables were associated with cardiac events.The patients in the 1st quartile had the lowest cardiac index and stroke volume index, and the highest mean pulmonary arterial pressure, mean pulmonary capillary wedge pressure, and pulmonary vascular resistance compared with the 2nd, 3rd, and 4th quartiles. Fifty-four patients experienced cardiac events during the follow-up period (median 943 days. The event-free rate of the 1st quartile was significantly lower than that of the 3rd and 4th quartiles (66.7% vs 82.5% [3rd quartile], P = 0.008; and 92.1% [4th quartile], P < 0.001. The Cox hazard analysis revealed that PAC was significantly associated with cardiac events (HR 0.556, 95% CI 0.424-0.730, P < 0.001.PAC is useful in the prediction of cardiac event risk in LHD-PH patients.

  11. An observational study of adult admissions to a medical ICU due to adverse drug events.

    Science.gov (United States)

    Jolivot, Pierre-Alain; Pichereau, Claire; Hindlet, Patrick; Hejblum, Gilles; Bigé, Naïke; Maury, Eric; Guidet, Bertrand; Fernandez, Christine

    2016-12-01

    The objectives of the study were to estimate the incidence of intensive care unit (ICU) admissions due to adverse drug events (ADEs), to assess preventability, severity and costs of the corresponding ADE and to determine the leading causes of preventable ADEs. An observational study was conducted in a medical ICU of a teaching hospital from February 2013 to February 2014. A total of 743 consecutive admissions were included, and they involved 701 different patients. The included admissions were categorized into three groups (admissions due to preventable ADE, admissions due to unpreventable ADE and the control group). Among the 743 ICU admissions included during the study period, 173 (23.3 %) were due to ADE, with 102 (13.7 %) related to preventable ADE and 71 (9.6 %) to unpreventable ADE, yielding a preventability rate of ADE of 0.59 (102/173). Admissions due to unpreventable ADE concerned patients with more comorbidities, a greater number of drugs and higher Simplified Acute Physiology Score II than admissions due to preventable ADE and the control group admissions (n = 570). Hospital mortality rates, corresponding costs and length of stay were all similar in the preventable ADE and control groups, whereas they were always significantly higher in the unpreventable ADE group. ICU mortality, length of stay and the corresponding costs were similar in the three groups. Non-compliance was the principal leading cause of preventable ADE (n = 31/102). The 102 preventable ADE-related admissions accounted for a total of 528 days of hospitalization in the ICU, requiring a mean of 1.4 ICU beds per day over the one-year period, with an associated total cost amounting to 747,651 €. ADE was a major cause of admission in the studied ICU, and in 59 % of the cases, ADEs were preventable. The reported burden of ICU admissions due to ADE advocates for further investigations to explore how the rate of such admissions could be decreased.

  12. Potential future increase in extreme one-hour precipitation events over Europe due to climate change.

    Science.gov (United States)

    Larsen, A N; Gregersen, I B; Christensen, O B; Linde, J J; Mikkelsen, P S

    2009-01-01

    In this study the potential increase of extreme precipitation in a future warmer European climate has been examined. Output from the regional climate model (RCM) HIRHAM4 covering Europe has been analysed for two periods, a control period 1961-1990 and a scenario 2071-2100, the latter following the IPCC scenario A2. The model has a resolution of about 12 km, which is unique compared with existing RCM studies that typically operate at 25-50 km scale, and make the results relevant to hydrological phenomena occurring at the spatial scale of the infrastructure designed to drain off rainfall in large urban areas. Extreme events with one- and 24-hour duration were extracted using the Partial Duration Series approach, a Generalized Pareto Distribution was fitted to the data and T-year events for return periods from 2 to 100 years were calculated for the control and scenario period in model cells across Europe. The analysis shows that there will be an increase of the intensity of extreme events generally in Europe; Scandinavia will experience the highest increase and southern Europe the lowest. A 20 year 1-hour precipitation event will for example become a 4 year event in Sweden and a 10 year event in Spain. Intensities for short durations and high return periods will increase the most, which implies that European urban drainage systems will be challenged in the future.

  13. Thyrotoxic periodic paralysis due to excessive L-thyroxine replacement in a Caucasian man.

    LENUS (Irish Health Repository)

    Hannon, M J

    2009-09-01

    Thyrotoxic periodic paralysis is a potentially fatal complication of hyperthyroidism, more common in Asian races, which is defined by a massive intracellular flux of potassium. This leads to profound hypokalaemia and muscle paralysis. Although the paralysis is temporary, it may be lethal if not diagnosed and treated rapidly, as profound hypokalaemia may induce respiratory muscle paralysis or cardiac arrest. The condition is often misdiagnosed in the west due to its comparative rarity in Caucasians; however it is now increasingly described in Caucasians and is also being seen with increasing frequency in western hospitals due to increasing immigration and population mobility. Here we describe the case of a patient with panhypopituitarism due to a craniopharyngioma, who developed thyrotoxic periodic paralysis due to excessive L-thyroxine replacement. This disorder has been described in Asian subjects but, to our knowledge, thyrotoxic periodic paralysis secondary to excessive L-thyroxine replacement has never been described in Caucasians.

  14. The prominent 1.6-year periodicity in solar motion due to the inner planets

    Directory of Open Access Journals (Sweden)

    I. Charvátová

    2007-06-01

    Full Text Available The solar motion due to the inner (terrestrial planets (Mercury, Me; Venus, V; Earth, E; Mars, Ma has been calculated (here for the years 1868–2030. The author found these basic properties of this motion: the toroidal volume in which the Sun moves has the inner radius of 101.3 km and the outer radius of 808.2 km. The solar orbit due to the inner (terrestrial planets is "heart-shaped". The orbital points which are the closest to the centre lie at the time distance of 1.6 years (584 days, on the average, and approximately coincide with the moments of the oppositions of V and E. The spectrum of periods shows the dominant period of 1.6 years (V-E and further periods of 2.13 years (E-Ma (25.6 months, QBO, 0.91 years (V-Ma, 0.8 years ((V-E/2 and 6.4 years. All the periods are above the 99% confidence level. A possible connection of this solar motion with the mid-term quasi-periodicities (MTQP, i.e. 1.5–1.7 years in solar and solar-terrestrial indices can be proposed.

  15. The Incubation Period of Primary Epstein-Barr Virus Infection: Viral Dynamics and Immunologic Events.

    Directory of Open Access Journals (Sweden)

    Samantha K Dunmire

    2015-12-01

    concert with viral genomes increasing in the blood and oral cavity, possibly due to a systemic type I interferon response. This study provides the first description of events during the incubation period of natural EBV infection in humans and definitive data upon which to formulate theories of viral control and disease pathogenesis.

  16. Periodic Impact Cratering and Extinction Events Over the Last 260 Million Years

    Science.gov (United States)

    Rampino, Michael R.; Caldeira, Ken

    2015-01-01

    The claims of periodicity in impact cratering and biological extinction events are controversial. Anewly revised record of dated impact craters has been analyzed for periodicity, and compared with the record of extinctions over the past 260 Myr. A digital circular spectral analysis of 37 crater ages (ranging in age from 15 to 254 Myr ago) yielded evidence for a significant 25.8 +/- 0.6 Myr cycle. Using the same method, we found a significant 27.0 +/- 0.7 Myr cycle in the dates of the eight recognized marine extinction events over the same period. The cycles detected in impacts and extinctions have a similar phase. The impact crater dataset shows 11 apparent peaks in the last 260 Myr, at least 5 of which correlate closely with significant extinction peaks. These results suggest that the hypothesis of periodic impacts and extinction events is still viable.

  17. A database of high-impact weather events in Greece: a descriptive impact analysis for the period 2001–2011

    Directory of Open Access Journals (Sweden)

    K. Papagiannaki

    2013-03-01

    Full Text Available This paper introduces the development of a database of high-impact weather events that occurred in Greece since 2001. The selected events are related to the occurrence of floods, flash floods, hail, snow/frost, tornados, windstorms, heat waves and lightning with adverse consequences (excluding those related to agriculture. The database includes, among others, the geographical distribution of the recorded events, relevant meteorological data, a brief description of the induced impacts and references in the press. This paper further offers an extensive analysis of the temporal and spatial distribution of high-impact weather events for the period 2001–2011, taking into account the intensity of weather conditions and the consequent impact on the society. Analysis of the monthly distribution of high-impact weather events showed that they are more frequent during October and November. More than 80 people lost their lives, half of which due to flash floods. In what concerns the spatial distribution of high-impact weather events, among the 51 prefectures of the country, Attica, Thessaloniki, Elia and Halkidiki were the most frequently affected areas, mainly by flash floods. Significant was also the share of tornados in Elia, of windstorms in Attica, of lightning and hail events in Halkidiki and of snow/frost events in Thessaloniki.

  18. Analyzing and Identifying Teens' Stressful Periods and Stressor Events From a Microblog.

    Science.gov (United States)

    Li, Qi; Xue, Yuanyuan; Zhao, Liang; Jia, Jia; Feng, Ling

    2017-09-01

    Increased health problems among adolescents caused by psychological stress have aroused worldwide attention. Long-standing stress without targeted assistance and guidance negatively impacts the healthy growth of adolescents, threatening the future development of our society. So far, research focused on detecting adolescent psychological stress revealed from each individual post on microblogs. However, beyond stressful moments, identifying teens' stressful periods and stressor events that trigger each stressful period is more desirable to understand the stress from appearance to essence. In this paper, we define the problem of identifying teens' stressful periods and stressor events from the open social media microblog. Starting from a case study of adolescents' posting behaviors during stressful school events, we build a Poisson-based probability model for the correlation between stressor events and stressful posting behaviors through a series of posts on Tencent Weibo (referred to as the microblog throughout the paper). With the model, we discover teens' maximal stressful periods and further extract details of possible stressor events that cause the stressful periods. We generalize and present the extracted stressor events in a hierarchy based on common stress dimensions and event types. Taking 122 scheduled stressful study-related events in a high school as the ground truth, we test the approach on 124 students' posts from January 1, 2012 to February 1, 2015 and obtain some promising experimental results: (stressful periods: recall 0.761, precision 0.737, and F1-measure 0.734) and (top-3 stressor events: recall 0.763, precision 0.756, and F1 -measure 0.759). The most prominent stressor events extracted are in the self-cognition domain, followed by the school life domain. This conforms to the adolescent psychological investigation result that problems in school life usually accompanied with teens' inner cognition problems. Compared with the state-of-the-art top-1

  19. Avian wildlife mortality events due to salmonellosis in the United States, 1985-2004

    Science.gov (United States)

    Hall, A.J.; Saito, E.K.

    2008-01-01

    Infection with Salmonella spp. has long been recognized in avian wildlife, although its significance in causing avian mortality, and its zoonotic risk, is not well understood. This study evaluates the role of Salmonella spp. in wild bird mortality events in the United States from 1985 through 2004. Analyses were performed to calculate the frequency of these events and the proportional mortality by species, year, month, state, and region. Salmonellosis was a significant contributor to mortality in many species of birds; particularly in passerines, for which 21.5% of all mortality events involved salmonellosis. The proportional mortality averaged a 12% annual increase over the 20-yr period, with seasonal peaks in January and April. Increased salmonellosis-related mortality in New England, Southeastern, and Mountain-Prairie states was identified. Based on the results of this study, salmonellosis can be considered an important zoonotic disease of wild birds. ?? Wildlife Disease Association 2008.

  20. [Pre-surgical period and non-work-related sickness absence due to inguinal hernia].

    Science.gov (United States)

    Ruiz-Moraga, Montserrat; Catalina-Romero, Carlos; Martínez-Muñoz, Paloma; Cobo-Santiago, María Dolores; González-López, Maite; Cabrera-Sierra, Martha; Porrero-Carro, José Luis; Calvo-Bonacho, Eva

    2014-04-01

    To analyze non-work-related sickness absence (NWR-SA) due to inguinal hernia and the factors related to its duration, paying particular attention to the pre-surgical period of NWR-SA. Prospective cohort study was conducted on 1,003 workers with an episode of NWR-SA due to an inguinal hernia, belonging to the insured population of a mutual insurance company. We assessed the duration of the NWR-SA episodes and the main demographic, occupational and clinical variables potentially related to it. Cox regression analyses were conducted to establish the predictors of NWR-SA duration. The mean duration of NWR-SA due to inguinal hernia was 68.6 days. After multivariate analysis (Cox regression), having a pre-surgical period of NWR-SA (HR = 0.35; 95%CI: 0.28-0.43), manual occupations (HR=0.68; 95%CI: 0.49-0.95), construction sector (HR=0.71; 95%CI: 0.58-0.88), direct payment methods by a Mutual Insurance Company during sick leave in self-employed workers (HR=0.58; 95%CI, 0.41-0.82), or employees (HR=0.51; 95%CI: 0.36-0.72), comorbidity (HR=0.45; 95%CI:0.34-0.59), and surgery performed under an entity other than the Public Health System or a mutual insurance company (HR=0,76; 95%CI: 0.59-0.97) were associated with longer NWR-SA. The Mutual Insurance Company always performed the surgery when a pre-surgery period of NWR-SA existed (mean duration=47 ±39.6 days); that was associated with shorter periods of post-surgical NWR-SA (P=.001). The NWR-SA due to inguinal hernia is a multifactorial phenomenon in which the pre-surgery period plays an important role. The collaboration between organizations involved in the management of NWR-SA seems to be an effective strategy for reducing its duration. Copyright © 2012 AEC. Published by Elsevier Espana. All rights reserved.

  1. An Open source GIS-based tool for economic loss estimation due to flood events

    OpenAIRE

    Sterlacchini, Simone; Zazzeri, Marco; Cappellini, Giacomo; Pastormerlo, Michele; Bonazzi, Alessandro

    2017-01-01

    Two complementary GIS-based functions are designed and implemented to assess the expected degree of loss due to the occurrence of flood events. Each function processes institutional thematic layers and allows decision makers first to quantify the physical and the economic exposure of the elements at risk in a given study region and then to assess the expected degree of economic loss in relation to the flood water depth chosen for the analysis. The functions are implemented using QGIS with GRA...

  2. Uncertainty of Intensity-Duration-Frequency (IDF) curves due to varied climate baseline periods

    Science.gov (United States)

    Fadhel, Sherien; Rico-Ramirez, Miguel Angel; Han, Dawei

    2017-04-01

    Storm water management systems depend on Intensity-Duration-Frequency (IDF) curves as a standard design tool. However, due to climate change, the extreme precipitation quantiles represented by IDF curves will be subject to alteration over time. Currently, a common approach is to adopt a single benchmark period for bias correction, which is inadequate in deriving reliable future IDF curves. This study assesses the expected changes between the IDF curves of the current climate and those of a projected future climate and the uncertainties associated with such curves. To provide future IDF curves, daily precipitation data simulated by a 1-km regional climate model were temporally bias corrected by using eight reference periods with a fixed length of 30 years and a moving window of 5 years between the cases for the period 1950-2014. Then the bias-corrected data were further disaggregated into ensemble of 5-min series by using an algorithm which combines the Nonparametric Prediction (NPRED) model and the method of fragments (MoF) framework. The algorithm uses the radar data to resample the disaggregated future rainfall fragments conditioned to the daily rainfall and temperature data. The disaggregated data were then aggregated into different durations based on concentration time. The results suggest that uncertainty in the percentage of change in the projected rainfall compared to the rainfall in the current climate varies significantly depending on which of the eight reference periods are used for the bias correction. Both the maximum projection of rainfall intensity and the maximum change in future projections are affected by using different reference periods for different frequencies and durations. Such an important issue has been largely ignored by the engineering community and this study has shown the importance of including the uncertainty of benchmarking periods in bias-correcting future climate projections.

  3. Tune shift effect due to the multipole longitudinal periodic structure in the superconducting dipole magnets

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, G.; Chen, S.

    1991-10-01

    Neglecting the curvature terms, the magnetic field and the vector potential which generate the multipole longitudinal periodic structure in a superconducting dipole magnet are found. Using this field and the standard Hamiltonian perturbation theory, the tune shifts due to this periodic pattern in the superconducting dipole magnets are estimated for the Superconducting Super Collider (SSC) machine. The results suggest that this tune shift is very small for most of the multipoles and could be ignored for the SSC. However, for the quadrupole longitudinal oscillation pattern, the tune shift relative to the amplitude of this oscillation could be of the order of 10{sup {minus}5} and may not be ignored. 12 refs., 4 figs., 3 tabs.

  4. Inhibition of quantum transport due to 'scars' of unstable periodic orbits

    Science.gov (United States)

    Jensen, R. V.; Sanders, M. M.; Saraceno, M.; Sundaram, B.

    1989-01-01

    A new quantum mechanism for the suppression of chaotic ionization of highly excited hydrogen atoms explains the appearance of anomalously stable states in the microwave ionization experiments of Koch et al. A novel phase-space representation of the perturbed wave functions reveals that the inhibition of quantum transport is due to the selective excitation of wave functions that are highly localized near unstable periodic orbits in the chaotic classical phase space. The 'scarred' wave functions provide a new basis for the quantum description of a variety of classically chaotic systems.

  5. Increased thermohaline stratification as a possible cause for an ocean anoxic event in the Cretaceous period.

    Science.gov (United States)

    Erbacher, J; Huber, B T; Norris, R D; Markey, M

    2001-01-18

    Ocean anoxic events were periods of high carbon burial that led to drawdown of atmospheric carbon dioxide, lowering of bottom-water oxygen concentrations and, in many cases, significant biological extinction. Most ocean anoxic events are thought to be caused by high productivity and export of carbon from surface waters which is then preserved in organic-rich sediments, known as black shales. But the factors that triggered some of these events remain uncertain. Here we present stable isotope data from a mid-Cretaceous ocean anoxic event that occurred 112 Myr ago, and that point to increased thermohaline stratification as the probable cause. Ocean anoxic event 1b is associated with an increase in surface-water temperatures and runoff that led to decreased bottom-water formation and elevated carbon burial in the restricted basins of the western Tethys and North Atlantic. This event is in many ways similar to that which led to the more recent Plio-Pleistocene Mediterranean sapropels, but the greater geographical extent and longer duration (approximately 46 kyr) of ocean anoxic event 1b suggest that processes leading to such ocean anoxic events in the North Atlantic and western Tethys were able to act over a much larger region, and sequester far more carbon, than any of the Quaternary sapropels.

  6. Vegetation Cover and Furrow Erosion due to Extreme Rain Events in Semiarid Environments

    Directory of Open Access Journals (Sweden)

    Belén Cárceles-Rodríguez

    2017-05-01

    Full Text Available The conservation of the soil resource in semi-arid environments is one of the major challenges of agricultural systems, particularly in the Mediterranean region. In the present study, two types of soil management were compared: minimum tillage (ML and minimum tillage with spontaneous vegetation cover (MLVE. The comparison was conducted in a rainfed almond plantation at slope (35%, under an extraordinary event in 2015 (91.3 mm and EI30 of 2,719.89 mm ha-1 h-1. In this situation in MLVE plots, the development of furrows in contrast to ML were not recorded; the total soil loss was more than 12 times lower than that recorded in the latter. This fact demonstrated the effectiveness of the vegetal cover in the protection of the agricultural soil against the erosion during extreme events. Also, for ML management, furrow erosion represented more than 60% of the total soil loss, demonstrating the dominance of this type of erosion. Finally, it should be noted that this event represents the almost total loss of soil recorded in the experimental plots during the period 2012-2015; and this consequently shows the significant impact of extreme events on erosion rates in the Mediterranean region.

  7. An Investigation of the Ionospheric Disturbances Due to the 2014 Sudden Stratospheric Warming Events Over Brazilian Sector

    Science.gov (United States)

    de Jesus, R.; Batista, I. S.; Jonah, O. F.; de Abreu, A. J.; Fagundes, P. R.; Venkatesh, K.; Denardini, C. M.

    2017-11-01

    The present study investigates the ionospheric F region response in the Brazilian sector due to sudden stratospheric warming (SSW) events of 2014. The data used for this work are obtained from GPS receivers and magnetometer measurements during day of year (DOY) 01 to 120, 2014 at different stations in the equatorial and low-latitude regions in the Brazilian sector. In addition, the data obtained from Communication/Navigation Outage Forecasting System satellites during DOY 01 to 75 of 2014 are used. The main novelty of this research is that, during the 2014 SSW events, daytime vertical total electron content (VTEC) shows a strong increase on the order of about 23% and 11% over the equatorial and low-latitude regions, respectively. We also observed that the nighttime VTEC (SSW days) is increased by 8% and 33% over equatorial and low-latitude regions, respectively. The magnetometer measurements show a strong counterelectrojet during the SSW days. The results show an amplification of the 0.5 day and 2-16 day periods in the VTEC and equatorial electrojet during the SSWs. The occurrences of ionospheric irregularities during the SSW events are around 84% and 53% in the equatorial and low-latitude regions, respectively, which is less frequent when compared with those during the pre-SSW periods.

  8. The validity of a patient-reported adverse drug event questionnaire using different recall periods

    NARCIS (Netherlands)

    de Vries, Sieta T; Haaijer-Ruskamp, Flora M; de Zeeuw, Dick; Denig, Petra

    2014-01-01

    PURPOSE: To assess the validity of a patient-reported adverse drug events (ADEs) questionnaire with a 3-month or 4-week recall period. METHODS: Patients receiving at least one oral glucose-lowering drug were asked to report potential ADEs they experienced related to any drug in a daily diary for a

  9. Long-period seismic events with strikingly regular temporal patterns on Katla volcano's south flank (Iceland)

    OpenAIRE

    Sgattoni, Giulia; Jeddi, Zeinab; Guðmundsson, Ólafur; Einarsson, Páll; Tryggvason, Ari; LUND, Björn; Lucchi, Federico

    2015-01-01

    Katla is a threatening volcano in Iceland, partly covered by the M\\'yrdalsj\\"okull ice cap. The volcano has a large caldera with several active geothermal areas. A peculiar cluster of long-period seismic events started on Katla's south flank in July 2011, during an unrest episode in the caldera that culminated in a glacier outburst. The seismic events were tightly clustered at shallow depth in the Gvendarfell area, 4 km south of the caldera, under a small glacier stream on the southern margin...

  10. To what extent can global warming events influence scaling properties of climatic fluctuations in glacial periods?

    Science.gov (United States)

    Alberti, Tommaso; Lepreti, Fabio; Vecchio, Antonio; Carbone, Vincenzo

    2017-04-01

    The Earth's climate is an extremely unstable complex system consisting of nonlinear and still rather unknown interactions among atmosphere, land surface, ice and oceans. The system is mainly driven by solar irradiance, even if internal components as volcanic eruptions and human activities affect the atmospheric composition thus acting as a driver for climate changes. Since the extreme climate variability is the result of a set of phenomena operating from daily to multi-millennial timescales, with different correlation times, a study of the scaling properties of the system can evidence non-trivial persistent structures, internal or external physical processes. Recently, the scaling properties of the paleoclimate changes have been analyzed by distinguish between interglacial and glacial climates [Shao and Ditlevsen, 2016]. The results show that the last glacial record (20-120 kyr BP) presents some elements of multifractality, while the last interglacial period (0-10 kyr BP), say the Holocene period, seems to be characterized by a mono-fractal structure. This is associated to the absence of Dansgaard-Oeschger (DO) events in the interglacial climate that could be the cause for the absence of multifractality. This hypothesis is supported by the analysis of the period between 18 and 27 kyr BP, i.e. during the Last Glacial Period, in which a single DO event have been registred. Through the Empirical Mode Decomposition (EMD) we were able to detect a timescale separation within the Last Glacial Period (20-120 kyr BP) in two main components: a high-frequency component, related to the occurrence of DO events, and a low-frequency one, associated to the cooling/warming phase switch [Alberti et al., 2014]. Here, we investigate the scaling properties of the climate fluctuations within the Last Glacial Period, where abrupt climate changes, characterized by fast increase of temperature usually called Dansgaard-Oeschger (DO) events, have been particularly pronounced. By using the

  11. Characteristics of Long-Period Events Associated With Volcanic Degassing at Popocatepetl Volcano, Mexico.

    Science.gov (United States)

    Arciniega, A.; Chouet, B.; Dawson, P.

    2004-05-01

    Emissions of gas and ash dominate volcanic eruptive activity in Popocatepetl volcano since 1994. Volcanic eruptive activity consists of construction and destruction dome phases. Ash emissions ranged from small short-lived plumes rising a few hundred meters above the crater rim, to larger plumes reaching up to 15 km above the crater. Resulting tephra falls dusted the entire summit area. Bursts of volcanic degassing accompanied by long-period (LP) seismic signals observed as isolated events, or as sequences of discrete events with overall durations and amplitudes. Some gas emissions accompanied by persistent or spasmodic tremor. There are four families of LP events identified within the frequency range between 0.5 and 5 Hz. Family-one presents low-frequency emergent onsets with higher amplitudes at higher frequencies. Family-two includes emergent onsets with modulate amplitudes simulating tremor and dominant frequencies in defined picks in the band between 1 and 3 Hz. Family-three presents LP events with impulsive onset and decaying amplitude with time, these events present a wide range of amplitudes and dominant frequencies around 2 Hz. Family-four includes LP events with monochromatic appearance with sharp picks below 3 Hz. From thousands of LP events preliminary locations based on phase picks suggest that LP seismicity occur within uppermost 1000 m below the crater floor, consistently constrain defined clusters in the east-region of the crater and in the area where the domes growth. The network used to located LP events included 15 broadband stations distributed along radial profiles on the upper flanks of Popocatepetl. We report data collected during a broadband seismic experiment carried out at Popocatepetl Volcano as part of an international cooperative program between the GeoForschungsZentr um, Potsdam, Germany, the U.S. Geological Survey and the Institute of Geophysics, UNAM, MEXICO.

  12. Long-period seismic events with strikingly regular temporal patterns on Katla volcano's south flank (Iceland)

    CERN Document Server

    Sgattoni, Giulia; Guðmundsson, Ólafur; Einarsson, Páll; Tryggvason, Ari; Lund, Björn; Lucchi, Federico

    2015-01-01

    Katla is a threatening volcano in Iceland, partly covered by the M\\'yrdalsj\\"okull ice cap. The volcano has a large caldera with several active geothermal areas. A peculiar cluster of long-period seismic events started on Katla's south flank in July 2011, during an unrest episode in the caldera that culminated in a glacier outburst. The seismic events were tightly clustered at shallow depth in the Gvendarfell area, 4 km south of the caldera, under a small glacier stream on the southern margin of M\\'yrdalsj\\"okull. No seismic events were known to have occurred in this area before. The most striking feature of this seismic cluster is its temporal pattern, characterized by regular intervals between repeating seismic events, modulated by a seasonal variation. Remarkable is also the stability of both the time and waveform features over a long time period, around 3.5 years. No comparable examples have been found in the literature. Both volcanic and glacial processes can produce similar waveforms and therefore have ...

  13. The emergence and evolution of the idea of discharge or modification of contract due to supervening events

    Directory of Open Access Journals (Sweden)

    Dudaš Atila I.

    2015-01-01

    Full Text Available In this paper the author gives an overview of the emergence and evolution of the idea of discharge or modification of contract due to supervening events, from Roman to contemporary law, with special emphasis on the evolution of the doctrine and its development as a legal institution in the European legislation or case law. The institution of changed circumstances (supervening events allows the discharge or (judicial modification of a contract in a situation when the performance of an obligation has not become impossible, but it would require unreasonable costs or the performance would be inexpedient, hence it is considered one of the most striking exceptions to the principle of pacta sunt servanda. It belongs to the group of a very few institutions in relation to which one cannot claim to have direct and clear roots in Roman law. In the works of learned lawyers one may find only sporadic traces of it. In contrast to Roman legal science, Roman philosophy was more favourable to the theory of supervening events, a fact very well proven by the works of Cicero and Seneca. In the late Middle Ages the canonists and, especially, postglossators gave the greatest contribution to the evolution of the theory of supervening events. The school of postglossators considered supervening events a general legal institution, tacitly implied in every legal statement constituting obligation. The ideas of postglossators left a great impact on further evolution of the theory. Even the designation of the institution, clausula rebus sic stantibus, generally accepted in contemporary literature, derives from them. In the period following the postglossators' time, lasting until the end of the 18th century, there is still an interest in the theory of supervening events in literature. However, under the influence of the school of natural law a somewhat restrictive approach is adopted, in the German doctrine in the first place, according to which the clausula rebus sic

  14. Sediment transport due to extreme events: The Hudson River estuary after tropical storms Irene and Lee

    Science.gov (United States)

    Ralston, David K.; Warner, John C.; Geyer, W. Rockwell; Wall, Gary R.

    2013-01-01

    Tropical Storms Irene and Lee in 2011 produced intense precipitation and flooding in the U.S. Northeast, including the Hudson River watershed. Sediment input to the Hudson River was approximately 2.7 megaton, about 5 times the long-term annual average. Rather than the common assumption that sediment is predominantly trapped in the estuary, observations and model results indicate that approximately two thirds of the new sediment remained trapped in the tidal freshwater river more than 1 month after the storms and only about one fifth of the new sediment reached the saline estuary. High sediment concentrations were observed in the estuary, but the model results suggest that this was predominantly due to remobilization of bed sediment. Spatially localized deposits of new and remobilized sediment were consistent with longer term depositional records. The results indicate that tidal rivers can intercept (at least temporarily) delivery of terrigenous sediment to the marine environment during major flow events.

  15. Ignitor Vacuum Vessel Structural Design with Dynamic Loads Due to Plasma Disruption Event

    Science.gov (United States)

    Cucchiaro, Antonio; Crescenzi, Claudio; Mazzone, Giuseppe; Pizzuto, Aldo; Ramogida, Giuseppe; Roccella, Massimo; Bianchi, Aldo; Parodi, Bruno; Linari, Mauro; Lucca, Flavio; Marin, Anna; Coppi, Bruno

    2004-11-01

    The new reference plasma disruption for IGNITOR produces a significant increase of electromagnetic (EM) loads and requires a dynamic elastic-plastic structural analysis of the vacuum vessel (VV). The EM loads due to the worst disruption event (VDE) have been calculated using the MAXFEA 2D code and it is found that the stresses and deformation that would be produced on a relatively thin chamber could be excessive. A varying thickness configuration for the VV has been adopted on the basis of a step by step optimization with the aim of minimizing the vertical displacement while complying with the allowable plastic strains. A non-linear analysis is required with a modelling of the entire (360°) VV structure. With the new thickness distribution, the VV is capable to withstand several hundred of cycles under plasma disruption conditions in compliance with the ASME III code rules.

  16. Evidence Report: Risk of Acute Radiation Syndromes Due to Solar Particle Events

    Science.gov (United States)

    Carnell, Lisa; Blattnig, Steve; Hu, Shaowen; Huff, Janice; Kim, Myung-Hee; Norman, Ryan; Patel, Zarana; Simonsen, Lisa; Wu, Honglu

    2016-01-01

    Crew health and performance may be impacted by a major solar particle event (SPE), multiple SPEs, or the cumulative effect of galactic cosmic rays (GCR) and SPEs. Beyond low-Earth orbit, the protection of the Earth's magnetosphere is no longer available, such that increased shielding and protective mechanisms are necessary in order to prevent acute radiation sickness and impacts to mission success or crew survival. While operational monitoring and shielding are expected to minimize radiation exposures, there are EVA scenarios outside of low-Earth orbit where the risk of prodromal effects, including nausea, vomiting, anorexia, and fatigue, as well as skin injury and depletion of the blood-forming organs (BFO), may occur. There is a reasonable concern that a compromised immune system due to high skin doses from a SPE or due to synergistic space flight factors (e.g., microgravity) may lead to increased risk to the BFO. The primary data available at present are derived from analyses of medical patients and persons accidentally exposed to acute, high doses of low-linear energy transfer (LET) (or terrestrial) radiation. Data more specific to the space flight environment must be compiled to quantify the magnitude of increase of this risk and to develop appropriate protection strategies. In particular, information addressing the distinct differences between solar proton exposures and terrestrial exposure scenarios, including radiation quality, dose-rate effects, and non-uniform dose distributions, is required for accurate risk estimation.

  17. Changes of circulatory and nervous diseases mortality patterns during periods of exceptional solar events

    Science.gov (United States)

    Podolska, Katerina

    2017-04-01

    The paper contains a statistical analysis of exceptional solar events and daily numbers of deaths from diseases from ICD-10 group VI. Diseases of the nervous system, group IX. Diseases of the circulatory system, and overall daily numbers of deaths in the Czech Republic. It is demonstrated that neurological diseases exhibit greater instability during the period of rising and falling solar activity. Specifically, we study the daily number of deaths separately for both sexes at the age groups under 39 and 40+ during the Solar Cycles No. 23 and No. 24. We focus mainly on exceptional solar events such as a "Bastille Day event" on July 14, 2000 (class X5), "Halloween solar storm" on October 28, 2003 (class X17), and events on January 7, 1997, April 2, 2000 (class X20), or September 7, 2005 (class X15). Special attention is given to "St. Patrick's Day storm" on March 17, 2015, the strongest geomagnetic storm of the Solar Cycle No. 24 that occurred following a coronal mass ejection (CME). We investigate changes in daily numbers of deaths during 1 month before and 1 month after these exceptional solar events. We take specific storm dynamics of geophysical parameters into consideration, and we also apply the results of risky characteristics of expositions by ionospheric and geomagnetic parameters. It is verified that, for diseases of the nervous system, women are generally more sensitive than men. On the contrary, this differences between men and women are not found for diseases of the circulatory system. Our findings suggest that the impact of hazardous space weather conditions on human health depends on the specific course and strength of individual solar storm.

  18. From theoretical fixed return period events to real flooding impacts: a new approach to set flooding scenarios, thresholds and alerts

    Science.gov (United States)

    Parravicini, Paola; Cislaghi, Matteo; Condemi, Leonardo

    2017-04-01

    ARPA Lombardia is the Environmental Protection Agency of Lombardy, a wide region in the North of Italy. ARPA is in charge of river monitoring either for Civil Protection or water balance purposes. It cooperates with the Civil Protection Agency of Lombardy (RL-PC) in flood forecasting and early warning. The early warning system is based on rainfall and discharge thresholds: when a threshold exceeding is expected, RL-PC disseminates an alert from yellow to red. The conventional threshold evaluation is based on events at a fixed return period. Anyway, the impacts of events with the same return period may be different along the river course due to the specific characteristics of the affected areas. A new approach is introduced. It defines different scenarios, corresponding to different flood impacts. A discharge threshold is then associated to each scenario and the return period of the scenario is computed backwards. Flood scenarios are defined in accordance with National Civil Protection guidelines, which describe the expected flood impact and associate a colour to the scenario from green (no relevant effects) to red (major floods). A range of discharges is associated with each scenario since they cause the same flood impact; the threshold is set as the discharge corresponding to the transition between two scenarios. A wide range of event-based information is used to estimate the thresholds. As first guess, the thresholds are estimated starting from hydraulic model outputs and the people or infrastructures flooded according to the simulations. Eventually the model estimates are validated with real event knowledge: local Civil Protection Emergency Plans usually contain very detailed local impact description at known river levels or discharges, RL-PC collects flooding information notified by the population, newspapers often report flood events on web, data from the river monitoring network provide evaluation of actually happened levels and discharges. The methodology

  19. Automatic localization of backscattering events due to particulate in urban areas

    Science.gov (United States)

    Gaudio, P.; Gelfusa, M.; Malizia, Andrea; Parracino, Stefano; Richetta, M.; Murari, A.; Vega, J.

    2014-10-01

    Particulate matter (PM), emitted by vehicles in urban traffic, can greatly affect environment air quality and have direct implications on both human health and infrastructure integrity. The consequences for society are relevant and can impact also on national health. Limits and thresholds of pollutants emitted by vehicles are typically regulated by government agencies. In the last few years, the interest in PM emissions has grown substantially due to both air quality issues and global warming. Lidar-Dial techniques are widely recognized as a costeffective alternative to monitor large regions of the atmosphere. To maximize the effectiveness of the measurements and to guarantee reliable, automatic monitoring of large areas, new data analysis techniques are required. In this paper, an original tool, the Universal Multi-Event Locator (UMEL), is applied to the problem of automatically indentifying the time location of peaks in Lidar measurements for the detection of particulate matter emitted by anthropogenic sources like vehicles. The method developed is based on Support Vector Regression and presents various advantages with respect to more traditional techniques. In particular, UMEL is based on the morphological properties of the signals and therefore the method is insensitive to the details of the noise present in the detection system. The approach is also fully general, purely software and can therefore be applied to a large variety of problems without any additional cost. The potential of the proposed technique is exemplified with the help of data acquired during an experimental campaign in the field in Rome.

  20. Characterizing the exceptional 2014 drought event in São Paulo by drought period length

    Science.gov (United States)

    Zou, Yong; Macau, Elbert E. N.; Sampaio, Gilvan; Ramos, Antônio M. T.; Kurths, Jürgen

    2017-09-01

    In the last decade, the southeast region of Brazil has been suffering severe water shortages. Here, we propose to compute the expected drought period length to characterize the drought events in the region of São Paulo. We report the unique properties of the exceptional drought event during the austral summer 2014 by showing the differences and similarities to the very dry season in 2001 and the mild dry seasons in 2006 and 2015. Furthermore, we investigate the correlations of the abnormal precipitation deficit with the ocean and atmospheric patterns. In comparison to other drought events, we validate the hypothetical mechanism that underlies the exceptional drought 2014: (1) The existence of an anomalous high pressure center in the area acts as a blocking mechanism that prevents moisture transport from the Amazon and passage of cold front systems from south Brazil. This blocking high has been observed in all dry seasons considered, with much larger magnitude in 2014. (2) The much faster increasing trend of the anomalous sea surface temperature acts as a strong feedback which intensified the extreme climate conditions. The unprecedented increasing trend of the SST in 2014 was not observed in other climate variables representing a high pressure center. Therefore, we conclude that the exceptional drought 2014 was enhanced by the feedback mechanism of anomalous warming of SST in the South Atlantic Oceans, which was resulted from the anomalous high pressure.

  1. Stressful events, social support and coping strategies of primiparous women during the postpartum period: a qualitative study.

    Science.gov (United States)

    Razurel, C; Bruchon-Schweitzer, M; Dupanloup, A; Irion, O; Epiney, M

    2011-04-01

    to identify problems and events perceived as stressful by primiparous mothers during the postpartum period, and to explore the social support and coping strategies they used to face these situations. a qualitative study. Data were collected via semi-structured interviews and analysed using a content-analysis method. Geneva University Hospitals, Geneva, Switzerland from October 2006 to March 2007. 60 women interviewed six weeks after the birth at term of their first child. during the early postpartum period, interaction with caregivers was an important source of perceived stress. Upon returning home, the partner was considered as the primary source of social support, but the first need expressed was for material support. Breast feeding was perceived negatively by the new mothers, and this may be due to the difference between the actual problems encountered and the idealised expectations conveyed by prenatal information. Educational information dispensed by medical staff during the prenatal period was not put into practice during the postpartum period. Mothers expressed the need to be accompanied and counselled when problems arose and regretted the lack of long-term postpartum support. both the prenatal education and postpartum social support seem to mismatch women's needs and expectations. Concerted efforts are required by health professionals at the maternity unit and in the community to provide mothers with more adequate postpartum assistance. Copyright © 2009 Elsevier Ltd. All rights reserved.

  2. 77 FR 63225 - Extension of Statutory Period for Compensation for Certain Disabilities Due to Undiagnosed...

    Science.gov (United States)

    2012-10-16

    ... areas during the Gulf War era are afflicted with Gulf War Syndrome and prone to adverse effects and..., testing for possible effects on offspring, and the need for VA to examine Gulf War veterans before VA... Gulf War. This amendment is necessary to extend the period during which disabilities associated with...

  3. An assessment of radiation damage in space-based germanium detectors due to solar proton events

    NARCIS (Netherlands)

    Owens, Alan; Brandenburg, S.; Buis, E. -J.; Kliewiet, H.; Kraft, S.; Ostendorf, R. W.; Peacock, A.; Quarati, F.; Quirin, P.

    2007-01-01

    Radiation effects caused by solar proton events will be a common problem for many types of sensors on missions to the inner solar system because of the long cruise phases coupled with the inverse square scaling of solar particle events. As part of a study in support of the BepiColombo mission to

  4. Length-scale effect due to periodic variation of geometrically necessary dislocation densities

    DEFF Research Database (Denmark)

    Oztop, M. S.; Niordson, Christian Frithiof; Kysar, J. W.

    2013-01-01

    of high spatial resolution diffraction methods in a scanning electron microscope give a much more quantitative understanding of plastic deformation at small length scales. Specifically, geometrically necessary dislocation densities (GND) can now be measured and provide detailed information about...... of the saturation value of dislocation densities in these cell walls and dislocation structures. In this study, a strain gradient plasticity framework is extended by incorporating the physical quantities obtained from experimental observations: the quasi-periodicity and the saturation value of GND densities...

  5. Perioperative period in cardiac transplantation from donors with brain death due to methanol poisoning

    Directory of Open Access Journals (Sweden)

    V. N. Poptsov

    2017-01-01

    Full Text Available The successful use of donor hearts from people died of methanol poisoning helps reducing the deficit of donor organs for patients requiring urgent cardiac transplantation [3]. We present our experience of successful cardiac transplantations from 2 donors who died due to methanol poisoning. Given the possibility of performing a cardiac transplant from this group of donors a protocol has been developed at the V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs of the Ministry of Healthcare of the Russian Federation which includes clinical, laboratory and instrumental criteria for the selection of heart donor and recipient. The possibility of delayed onset myocardial contractile dysfunction due to methanol poisoning means that a longer conditioningperiod is vital as well as compulsory clinical, laboratory and expert chocardiographic examinations of the potential donor heart.

  6. The source of infrasound associated with long-period events at mount St. Helens

    Science.gov (United States)

    Matoza, R.S.; Garces, M.A.; Chouet, B.A.; D'Auria, L.; Hedlin, M.A.H.; De Groot-Hedlin, C.; Waite, G.P.

    2009-01-01

    During the early stages of the 2004-2008 Mount St. Helens eruption, the source process that produced a sustained sequence of repetitive long-period (LP) seismic events also produced impulsive broadband infrasonic signals in the atmosphere. To assess whether the signals could be generated simply by seismic-acoustic coupling from the shallow LP events, we perform finite difference simulation of the seismo-acoustic wavefield using a single numerical scheme for the elastic ground and atmosphere. The effects of topography, velocity structure, wind, and source configuration are considered. The simulations show that a shallow source buried in a homogeneous elastic solid produces a complex wave train in the atmosphere consisting of P/SV and Rayleigh wave energy converted locally along the propagation path, and acoustic energy originating from , the source epicenter. Although the horizontal acoustic velocity of the latter is consistent with our data, the modeled amplitude ratios of pressure to vertical seismic velocity are too low in comparison with observations, and the characteristic differences in seismic and acoustic waveforms and spectra cannot be reproduced from a common point source. The observations therefore require a more complex source process in which the infrasonic signals are a record of only the broadband pressure excitation mechanism of the seismic LP events. The observations and numerical results can be explained by a model involving the repeated rapid pressure loss from a hydrothermal crack by venting into a shallow layer of loosely consolidated, highly permeable material. Heating by magmatic activity causes pressure to rise, periodically reaching the pressure threshold for rupture of the "valve" sealing the crack. Sudden opening of the valve generates the broadband infrasonic signal and simultaneously triggers the collapse of the crack, initiating resonance of the remaining fluid. Subtle waveform and amplitude variability of the infrasonic signals as

  7. Log-periodic oscillations due to discrete effects in complex networks

    Science.gov (United States)

    Sienkiewicz, Julian; Fronczak, Piotr; Hołyst, Janusz A.

    2007-06-01

    We show how discretization affects two major characteristics in complex networks: internode distances (measured as the shortest number of edges between network sites) and average path length, and as a result there are log-periodic oscillations of the above quantities. The effect occurs both in numerical network models as well as in such real systems as coauthorship, language, food, and public transport networks. Analytical description of these oscillations fits well numerical simulations. We consider a simple case of the network optimization problem, arguing that discrete effects can lead to a nontrivial solution.

  8. Extreme dissipation event due to plume collision in a turbulent convection cell

    CERN Document Server

    Schumacher, Joerg

    2016-01-01

    An extreme dissipation event in the bulk of a closed three-dimensional turbulent convection cell is found to be correlated with a strong reduction of the large-scale circulation flow in the system that happens at the same time as a plume emission event from the bottom plate. The reduction in the large-scale circulation opens the possibility for a nearly frontal collision of down- and upwelling plumes and the generation of a high-amplitude thermal dissipation layer in the bulk. This collision is locally connected to a subsequent high-amplitude energy dissipation event in the form of a strong shear layer. Our analysis illustrates the impact of transitions in the large-scale structures on extreme events at the smallest scales of the turbulence, a direct link that is observed in a flow with boundary layers. We also show that detection of extreme dissipation events which determine the far-tail statistics of the dissipation fields in the bulk requires long-time integrations of the equations of motion over at least ...

  9. Sudden motor and sensorial loss due to retroperitoneal hematoma during postoperative periods: a case report

    Directory of Open Access Journals (Sweden)

    Pelin Şen

    Full Text Available Abstract A 68 year-old male patient was hospitalized for radical prostatectomy. He had no abnormal medical history including neurological deficit before the operation. Prior to general anesthesia, an epidural catheter was inserted in the L3-4 interspace for intraoperative and postoperative analgesia. After surgery for nine hours, he developed confusion and flaccid paralysis of bilateral lower extremities occurred. No pathology was detected from cranial computed tomography and diffusion magnetic resonance imaging no pathology was detected. His thoracic/lumbar magnetic resonance imaging. Intraabdominal pressure was shown to be 25 mmHg, and abdominal ultrasonography revealed progression in the inflammation/edema/hematoma in the perirenal region. The Bromage score was back to 1 in the right foot on the 24th hour and in the left foot on the 26th hour. Paraplegia developed in patients after epidural infusion might be caused by potentiated local anesthetic effect due to retroperitoneal hematoma and/or elevated intra-abdominal pressure.

  10. Lower-Extremity Weakness in a Teenager Due to Thyrotoxic Periodic Paralysis.

    Science.gov (United States)

    Thornton, Matthew D

    2017-04-01

    Thyrotoxic hypokalemic paralysis is the hallmark of thyrotoxic periodic paralysis (TPP). TPP is a potentially deadly complication of hyperthyroidism that occurs because of rapid and dramatic intracellular shift of potassium. This transference results in severe hypokalemia and clinically manifests itself as muscle weakness or paralysis. This condition predominantly affects males of Asian descent, and its presentation can range from mild to severe, as seen in our case. We present the case of a 15-year-old Asian-American male who presented to a tertiary-care pediatric emergency department complaining of generalized weakness and flaccid paralysis of his lower extremities. The differential for such a complaint is extremely broad, and the symptoms can result from etiologies arising from the cerebral cortex, the spinal cord, peripheral nerves, the neuromuscular junction, or even the muscles themselves. Our patient was found to have an extremely low serum potassium concentration, as well as an electrocardiogram that revealed a prolonged QT interval and right bundle branch block. The etiology of these abnormalities and the patient's symptoms was found to be undiagnosed and uncontrolled hyperthyroidism from Grave's disease, which resulted in this dramatic presentation of thyrotoxic hypokalemic paralysis. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: This entity is common in Asia but still somewhat rare in the United States and other Western countries. Our case illustrates that careful history taking and a focused diagnostic evaluation, in conjunction with having an awareness of this disease, can help expedite diagnosis and management, as well as avoid unnecessary and potential harmful testing in the emergency department setting. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Time off work due to scaphoid fractures and other carpal injuries in the Netherlands in the period 1990 to 1993

    NARCIS (Netherlands)

    Mink van der Molen, AB; Groothoff, JW; Visser, GJP; Robinson, PH; Eisma, WH

    This study assessed the epidemiology, treatment, disability and time off work due to carpal injuries in the Netherlands in the period from 1990 to 1993. Most injuries were scaphoid fractures and carpal instabilities were rare, The time off work was considerable (mean, 155 days; median, 105 days;

  12. Safety Evaluation for IHTS Integrity due to the Steam Generator Sodium-Water Reaction Event in the PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Sang-Jun; Lee, Kwi Lim; Ha, Kwi-Seok; Lee, Seung Won; Jeong, Taekyeong [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    In this paper, the integrity of the IHTS and SG by the SWR event are evaluated using the SWAAMII code. A sodium has a chemical characteristics to rigorously react the water or steam and produce the high pressure waves and high temperature reaction heat. It has an excellent characteristics as a reactor coolant. But, there is an event to be considered in the sodium cooled fast reactor design. The Sodium-Water Reaction (SWR) event can be occurred by the water or steam leaks due to the break of the steam generator tubes. The propagated high pressure waves threathen the structural integrity of the affected Intermediate Heat Transport System (IHTS) and steam generator. If the IHTS pipes are failed, the sodium of the IHTS can be released to the containment building. To the peak pressure point of view, it is performed to evaluate the integrity of the major components due to the SWR event in the SG. The generated peak pressures due to the five SG tubes simultaneous break event are within the range of the design pressure for the SG, IHX and IHTS including the related pipes.

  13. Sediment transport due to windthrow event in the Tatra Mountains, Poland

    Science.gov (United States)

    Strzyżowski, Dariusz; Fidelus-Orzechowska, Joanna

    2017-04-01

    Mountain areas are frequently affected by strong wind events which cause damage in forest stands by snapping or uprooting of trees. Uprooting contributes to sediment transport by displacement of soil material attached to a root system of a tree. The aim of the study was to investigate geomorphic effects of tree uprooting and to calculate sediment flux by windthrow for the area of Tatra National Park. Research was conducted within the Tatra Mountains, in the Tatra National Park. Windthrow event occurred on 25 December 2013. The field work was conducted from September to November 2015 within 7 research polygons with the total area of 0.97 ha. Type of the damage (uprooted, partly uprooted, snapped), dimensions of a root plate, slope inclination, aspect, angle of tree fall, and tree diameter were determined for every damaged tree. Also, basing on GIS analysis, area of the windthrow and directions of fallen trunks for the whole area of Tatra National Park were determined. In total 252 damaged trees were investigated. 66% of them were uprooted, 25% were snapped, and 9% were partly uprooted. Slope inclination, aspect, and tree diameter did not influence type of the damage significantly. Mean volume of a root plate is 2.7 m3, and the amount of uplifted material is 378.4 m3 ha-1. Totally within the Tatra National Park area 297.9 ha of the forest were affected. 77% of the tree trunks were fallen in downslope direction. Sediment flux by windthrow event in 2013, for the forested part of the Tatra National Park is at the order of magnitude of 10-4 m3 m-1.

  14. Venous thromboembolism and subsequent hospitalisation due to acute arterial cardiovascular events: a 20-year cohort study

    DEFF Research Database (Denmark)

    Sørensen, Henrik Toft; Horvath-Puho, Erzsebet; Pedersen, Lars

    2007-01-01

    of myocardial infarction and stroke in 25,199 patients with deep venous thrombosis, 16,925 patients with pulmonary embolism, and 163,566 population controls. FINDINGS: For patients with deep venous thrombosis, the relative risks varied from 1.60 for myocardial infarction (95% CI 1.35-1.91) to 2.19 (1.......85-2.60) for stroke in the first year after the thrombotic event. For patients with pulmonary embolism, the relative risks in that year were 2.60 (2.14-3.14) for myocardial infarction and 2.93 (2.34-3.66) for stroke. The relative risks were also raised, though less markedly, during the subsequent 20 years of follow......-up, with 20-40% increases in risk for arterial cardiovascular events. Relative risks were similar for those with provoked and unprovoked deep venous thrombosis and pulmonary embolism. INTERPRETATION: Patients with venous thromboembolism have a substantially increased long-term risk of subsequent arterial...

  15. Skeletal-related events due to bone metastases from differentiated thyroid cancer.

    Science.gov (United States)

    Farooki, Azeez; Leung, Vivien; Tala, Hernan; Tuttle, R Michael

    2012-07-01

    In oncology, the clinical impact of metastatic bone disease is conveyed via a composite end point termed skeletal-related events (SRE), which encompasses spinal cord compression, pathological fracture, a need for external beam radiation or surgery to bone, and hypercalcemia of malignancy. An appreciation for the high incidence of SRE in other advanced cancers involving the bone has led to the approval of potent antiresorptive agents because they delay the time to the first SRE and decrease the incidence of SRE. The risk and rate of SRE after diagnosis of bone metastasis have not been described in thyroid cancer; antiresorptive agents are not routinely used. This was a retrospective review of 245 differentiated thyroid cancer patients with bone metastases identified as part of routine clinical care at Memorial Sloan-Kettering Cancer Center between 1960 and 2011. The occurrence of SRE was recorded from the initial diagnosis of bone metastasis until final follow-up or death. Seventy-eight percent of patients (192 of 245) either presented with or developed at least one SRE after the diagnosis of metastatic bone disease. The median time from identification of bone metastasis to first SRE was 5 months (excluding the 97 patients in whom first SRE occurred at the time of the bone metastasis diagnosis). Of the patients who sustained an initial SRE, 65% (120 of 192) went on to sustain a second SRE at a median of 10.7 months after the first event. SRE were frequently multiple; 39% (74 of 192) sustained three or more discrete SRE. Thyroid cancer bone metastases identified as part of routine clinical follow-up frequently cause significant and recurrent morbidity. The incidence of SRE and median time to first SRE in metastatic thyroid cancer to bone are similar to those reported in other solid tumors. Prospective clinical trials to assess the efficacy of antiresorptive agents in this population are needed.

  16. A general approach for temperature modulated thermogravimetry: Extension to non-periodical and event-controlled modulation

    Energy Technology Data Exchange (ETDEWEB)

    Schawe, J.E.K., E-mail: juergen.schawe@mt.com

    2014-10-10

    Highlights: • The temperature modulated TGA technique is expanded to non-periodic modulation functions. • The use of a stochastic modulation function is tested. • The concept of the new technique, the event controlled temperature modulated TGA is introduced. • The event control adapted the intensity of the modulation function and the characteristic modulation time. The result is an optimized modulation. - Abstract: Sinusoidal temperature modulated thermogravimetric analysis (TMTGA) has been proposed to get kinetic data on reactions that were investigated by TGA 45 years ago by Flynn and later by Blaine and Hahn. Because of general uncertainties of this technique, we developed a generalized approach for TMTGA using any modulation function, i.e., periodic as well as non-periodic. As a consequence of an error discussion of a TMDSC experiment, we present a new concept of the event controlled modulation function.

  17. Quasi-Periodicities in the Anomalous Emission Events in Pulsars B1859+07 and B0919+06

    OpenAIRE

    Wahl, Haley M.; Orfeo, Daniel J.; Rankin, Joanna M.; Weisberg, Joel M.

    2016-01-01

    A quasi-periodicity has been identified in the strange emission shifts in pulsar B1859+07 and possibly B0919+06. These events, first investigated by Rankin, Rodriguez & Wright in 2006, originally appeared disordered or random, but further mapping as well as Fourier analysis has revealed that they occur on a fairly regular basis of approximately 150 rotation periods in B1859+07 and perhaps some 700 in B0919+06. The events-which we now refer to as "swooshes"-are not the result of any known type...

  18. Determining Storm Surge Return Periods: The Use of Evidence of Historic Events

    DEFF Research Database (Denmark)

    Madsen, Kristine S.; Sørensen, Carlo Sass; Schmith, Torben

    Storm surges are a major concern for many coastal communities, and rising levels of surges is a key concern in relation to climate change. The sea level of a statistical 100-year or 1000-year storm surge event and similar statistical measures are used for spatial planning and emergency preparedness....... These statistics are very sensitive to the assessments of past events, and to future sea level change. The probability of a major storm surge from the Baltic Sea hitting the Copenhagen metropolitan area is officially determined by the Danish Coastal Authority based on tide gauge records. We have a long history...... for tide gauge measurements, with 120 years of data available for the calculations. However, the oldest of these tide gauge stations was set up after a major storm surge in 1872, and no events of similar severity have occurred since. Including the evidence of the historic events from the 18th century...

  19. Analysis of the long and short-period terms due the nonsphericity of the central body: applications for Mercury

    Science.gov (United States)

    Carvalho, J. P. S.

    2017-10-01

    In this work, we present an approach taking into account the single-averaged equations and unaveraged equations to investigate the dynamics of artificial satellites on the effect due to the non-spherical shape of the planet Mercury. An analysis considering the long-period terms and another taking into account the short-period terms is presented. The numerical integrations of the equations developed are performed using the Maple software. We consider the numerical values of the most updated spherical harmonic coefficients in the literature. Emphasis is given to analyze the effect of the C22 term in the dynamics of the spacecraft. We show that the two techniques are in agreement (average or not average). We found orbits that librates around an equilibrium point with small variation of the orbital elements, in particular the eccentricity and argument of the pericenter. We also note that the C22 term contributes to reduce the growth of the orbital eccentricity.

  20. Venous thromboembolism in pregnancy and the puerperal period: a study of 1210 events

    DEFF Research Database (Denmark)

    Virkus, Rie Adser; Løkkegaard, Ellen Cl; Lidegaard, Ojvind

    2013-01-01

    The aim of this study was to describe venous thromboembolism (VTE) in pregnancy and the puerperal period and to validate diagnoses of VTE.......The aim of this study was to describe venous thromboembolism (VTE) in pregnancy and the puerperal period and to validate diagnoses of VTE....

  1. On the Mass and Luminosity Functions of Tidal Disruption Flares: Rate Suppression due to Black Hole Event Horizons

    Science.gov (United States)

    van Velzen, S.

    2018-01-01

    The tidal disruption of a star by a massive black hole is expected to yield a luminous flare of thermal emission. About two dozen of these stellar tidal disruption flares (TDFs) may have been detected in optical transient surveys. However, explaining the observed properties of these events within the tidal disruption paradigm is not yet possible. This theoretical ambiguity has led some authors to suggest that optical TDFs are due to a different process, such as a nuclear supernova or accretion disk instabilities. Here we present a test of a fundamental prediction of the tidal disruption event scenario: a suppression of the flare rate due to the direct capture of stars by the black hole. Using a recently compiled sample of candidate TDFs with black hole mass measurements, plus a careful treatment of selection effects in this flux-limited sample, we confirm that the dearth of observed TDFs from high-mass black holes is statistically significant. All the TDF impostor models we consider fail to explain the observed mass function; the only scenario that fits the data is a suppression of the rate due to direct captures. We find that this suppression can explain the low volumetric rate of the luminous TDF candidate ASASSN-15lh, thus supporting the hypothesis that this flare belongs to the TDF family. Our work is the first to present the optical TDF luminosity function. A steep power law is required to explain the observed rest-frame g-band luminosity, {dN}/{{dL}}g\\propto {L}g-2.5. The mean event rate of the flares in our sample is ≈ 1× {10}-4 galaxy‑1 yr‑1, consistent with the theoretically expected tidal disruption rate.

  2. Broadband wide-angle absorption enhancement due to mode conversion in cold unmagnetized plasmas with periodic density variations

    CERN Document Server

    Yu, Dae Jung

    2016-01-01

    We study theoretically the mode conversion and the associated resonant absorption of p-polarized electromagnetic waves into longitudinal plasma oscillations in cold, unmagnetized and stratified plasmas with periodic spatial density variations. We consider sinusoidal density configurations for which the frequency band where mode conversion occurs is well included within a transmission band of the one-dimensional plasma photonic crystal. We calculate the mode conversion coefficient, which measures the fraction of the electromagnetic wave energy absorbed into the plasma, and the spatial distribution of the magnetic field intensity for various values of the wave frequency and the incident angle using the invariant imbedding theory of mode conversion. We find that the absorption is greatly enhanced over a wide range of frequency and incident angle due to the interplay between the mode conversion and the photonic band structure. The enhancement occurs because for frequencies within a transmission band, the wave ref...

  3. Estimating Finite Source Effects in Microlensing Events due to Free-Floating Planets with the Euclid Survey

    Directory of Open Access Journals (Sweden)

    Lindita Hamolli

    2015-01-01

    Full Text Available In recent years free-floating planets (FFPs have drawn a great interest among astrophysicists. Gravitational microlensing is a unique and exclusive method for their investigation which may allow obtaining precious information about their mass and spatial distribution. The planned Euclid space-based observatory will be able to detect a substantial number of microlensing events caused by FFPs towards the Galactic bulge. Making use of a synthetic population algorithm, we investigate the possibility of detecting finite source effects in simulated microlensing events due to FFPs. We find a significant efficiency for finite source effect detection that turns out to be between 20% and 40% for a FFP power law mass function index in the range [0.9, 1.6]. For many of such events it will also be possible to measure the angular Einstein radius and therefore constrain the lens physical parameters. These kinds of observations will also offer a unique possibility to investigate the photosphere and atmosphere of Galactic bulge stars.

  4. Busy period analysis, rare events and transient behavior in fluid flow models

    Directory of Open Access Journals (Sweden)

    Søren Asmussen

    1994-01-01

    Full Text Available We consider a process {(Jt,Vt}t≥0 on E×[0,∞, such that {Jt} is a Markov process with finite state space E, and {Vt} has a linear drift ri on intervals where Jt=i and reflection at 0. Such a process arises as a fluid flow model of current interest in telecommunications engineering for the purpose of modeling ATM technology. We compute the mean of the busy period and related first passage times, show that the probability of buffer overflow within a busy cycle is approximately exponential, and give conditioned limit theorems for the busy cycle with implications for quick simulation. Further, various inequalities and approximations for transient behavior are given. Also explicit expressions for the Laplace transform of the busy period are found. Mathematically, the key tool is first passage probabilities and exponential change of measure for Markov additive processes.

  5. A periodic spatio-spectral filter for event-related potentials.

    Science.gov (United States)

    Ghaderi, Foad; Kim, Su Kyoung; Kirchner, Elsa Andrea

    2016-12-01

    With respect to single trial detection of event-related potentials (ERPs), spatial and spectral filters are two of the most commonly used pre-processing techniques for signal enhancement. Spatial filters reduce the dimensionality of the data while suppressing the noise contribution and spectral filters attenuate frequency components that most likely belong to noise subspace. However, the frequency spectrum of ERPs overlap with that of the ongoing electroencephalogram (EEG) and different types of artifacts. Therefore, proper selection of the spectral filter cutoffs is not a trivial task. In this research work, we developed a supervised method to estimate the spatial and finite impulse response (FIR) spectral filters, simultaneously. We evaluated the performance of the method on offline single trial classification of ERPs in datasets recorded during an oddball paradigm. The proposed spatio-spectral filter improved the overall single-trial classification performance by almost 9% on average compared with the case that no spatial filters were used. We also analyzed the effects of different spectral filter lengths and the number of retained channels after spatial filtering. Copyright © 2016. Published by Elsevier Ltd.

  6. Estimation of Seismic Loss for a Portfolio of Buildings under Bidirectional Horizontal Ground Motions due to a Scenario Cascadia Event

    Directory of Open Access Journals (Sweden)

    Taojun Liu

    2017-10-01

    Full Text Available Earthquake ground motions induced by a scenario event are spatially (partially correlated and (partially coherent. Simulated ground motion records can be used to carry out nonlinear inelastic time history analysis for a portfolio of buildings to estimate the seismic loss, which is advantageous as there is no need to develop and apply empirical ground motion prediction equations and the ductility demand rules, or to search the scenario-compatible recorded records at selected sites that may not exist. Further, if the structures being considered are sensitive to the orientation of the excitation, multiple-component ground motion records are needed. For the simulation of such ground motion records, previous studies have shown that correlation and coherency between any pair of ground motion components need to be incorporated. In this study, the seismic loss of a portfolio of hypothetical buildings in downtown Vancouver under bidirectional horizontal ground motions due to a scenario Cascadia event is estimated by using simulated bidirectional ground motion records that include realistic correlation and coherency characteristics. The hysteretic behaviors of the buildings are described by bidirectional Bouc–Wen model. The results show that the use of unidirectional ground motions and single-degree-of-freedom system structural model may underestimate the aggregated seismic loss.

  7. [Hospital admission due to adverse drug events (ADE): an analysis of German routine hospital data of 2006].

    Science.gov (United States)

    Amann, C; Hasford, J; Stausberg, J

    2012-10-01

    In developed countries 1-5% of all hospital admissions are due to adverse drug events (ADE). An ADE is defined as an injury resulting from medical intervention related to a drug. The established reporting systems and study designs only capture selective data. The objective of the current analysis was to evaluate the rate, distribution and correlations of ADE related admissions by using German routine data. ADEs were identified by an array of 502 specified codes of the ICD-10-GM. The evaluation included only verified codes and was carried out by remote queries of the German DRG-Statistics 2006. Hospital admission due to an ADE was identified via the primary diagnosis. Of all hospital admissions 0.92% were revealed to be certainly caused by an adverse drug event. The average age between affected and non-affected was nearly identical for women 53.48 vs. 53.67 years, for men it was reduced by 4 years (48.38 years). The average hospital stay was lower for cases with an ADE, being reduced by 1.3 days for women (6.26 days vs. 7.55 days) and 1.5 days for men (5.91 days vs. 7.42 days). While mortality with an odds ratio (OR) of 0.59 (95% CI 0.57-0.62) was lower in ADE cases, the rate of emergency admissions due to ADE was increased, the OR being 3.10 (95% CI 3.07-3.13). The wards with excess rates of ADE cases were internal medicine, paediatrics, dermatology, intensive care and neurology. Younger age, reduced hospital stay and lower mortality of ADE cases are contrary to findings in the relevant literature. The DRG-Statistics also comprise populations which often are excluded in established study designs, in particular, children and cases due to medication errors, overdose, poisoning and allergic reactions. As these cases respond easily to prevention and are of significant interest to pharmacovigilance, the use of routine data is valuable for more intense research of ADE. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Quasi-periodic slow slip events in the afterslip area of the 1996 Hyuga-nada earthquakes, Japan

    Science.gov (United States)

    Yarai, Hiroshi; Ozawa, Shinzaburo

    2013-05-01

    The time evolution of afterslip on a plate boundary experiencing interplate earthquakes is expected to show logarithmic decay. The global positioning system network in Japan has been monitoring transient deformation since the occurrence of two large interplate earthquakes with moment magnitudes of 6.8 and 6.7 in the Hyuga-nada area, southwest Japan, in 1996. The spatial and temporal evolution of aseismic interplate slip based on crustal deformation data indicates that afterslip followed the two earthquakes and gradually declined to background rates by around 2004 with total moment magnitude of 7.3. However, quasi-periodic slow slip events suddenly began within the afterslip area in 2005 with approximately one year duration and two-year recurrence interval. The moment magnitudes of the three slow slip events since January 2005 range from 6.7 to 6.8. This differs greatly from the expected behavior of logarithmic decay over time. Both velocity-strengthening and velocity-weakening rate-and-state modes have been implicated as the cause of afterslip, whose location is complementary to the main shock area of velocity-weakening, while a slow slip event occurs in the velocity-weakening area with different frictional properties from those of an afterslip area. In light of the seemingly different frictional properties, the coexistence of afterslip and slow slip events in the same area would provide additional information about precisely how the plate interface is behaving. The monitoring of these slow slip events should give the clues to understanding the coexistence of long-term afterslip and slow slip events and the increasing risk of earthquakes in neighboring areas.

  9. The incidence of cardiovascular events after hospitalization due to CAP and their association with different inflammatory markers.

    Science.gov (United States)

    Rajas, Olga; Ortega-Gómez, Mara; Galván Román, José María; Curbelo, José; Fernández Jiménez, Guillermo; Vega Piris, Lorena; Rodríguez Salvanes, Francisco; Arnalich, Belén; Luquero Bueno, Sergio; Díaz López, Ana; de la Fuente, Hortensia; Suárez, Carmen; Ancochea, Julio; Aspa, Javier

    2014-12-12

    Late prognosis of Community-Acquired Pneumonia (CAP) patients is related to cardiovascular events. Persistence of inflammation-related markers, defined by high circulatory levels of interleukin 6 and 10 (IL-6/IL-10), is associated with a higher post-event mortality rate for CAP patients. However, association between these markers and other components of the immune response, and the risk of cardiovascular events, has not been adequately explored. The main objectives of this study are: 1) to quantify the incidence of cardiovascular disease, in the year post-dating their hospital admittance due to CAP and, 2) to describe the distribution patterns of a wide spectrum of inflammatory markers upon admittance to and release from hospital, and to determine their relationship with the incidence of cardiovascular disease. A cohort prospective study. All patients diagnosed and hospitalized with CAP will be candidates for inclusion. The study will take place in the Universitary Hospital La Princesa, Spain, during two years. Two samples of blood will be taken from each patient: the first upon admittance and the second one prior to release, in order to analyse various immune agents. The main determinants are: pro-adrenomedullin, copeptin, IL-1, IL-6, TNF-α, IL-17, IFN-γ, IL-10 and TGF-β, E-Selectin, ICAM-1, VCAM-1 and subpopulations of peripheral T lymphocytes (T regulator, Th1 and Th17), together with other clinical and analytical variables. Follow up will start at admittance and finish a year after discharge, registering incidence of death and cardiovascular events. The main objective is to establish the predictive power of different inflammatory markers in the prognosis of CAP, in the short and long term, and their relationship with cardiovascular disease. The level of some inflammatory markers (IL-6/IL-10) has been proposed as a means to differentiate the degree of severity of CAP, but their association with cardiovascular risk is not well established. In this study we aim

  10. Analysis of C3 suggests three periods of positive selection events and different evolutionary patterns between fish and mammals.

    Directory of Open Access Journals (Sweden)

    Fanxing Meng

    Full Text Available BACKGROUND: The third complement component (C3 is a central protein of the complement system conserved from fish to mammals. It also showed distinct characteristics in different animal groups. Striking features of the fish complement system were unveiled, including prominent levels of extrahepatic expression and isotypic diversity of the complement components. The evidences of the involvement of complement system in the enhancement of B and T cell responses found in mammals indicated that the complement system also serves as a bridge between the innate and adaptive responses. For the reasons mentioned above, it is interesting to explore the evolutionary process of C3 genes and to investigate whether the huge differences between aquatic and terrestrial environments affected the C3 evolution between fish and mammals. METHODOLOGY/PRINCIPAL FINDINGS: Analysis revealed that these two groups of animals had experienced different evolution patterns. The mammalian C3 genes were under purifying selection pressure while the positive selection pressure was detected in fish C3 genes. Three periods of positive selection events of C3 genes were also detected. Two happened on the ancestral lineages to all vertebrates and mammals, respectively, one happened on early period of fish evolutionary history. CONCLUSIONS/SIGNIFICANCE: Three periods of positive selection events had happened on C3 genes during history and the fish and mammals C3 genes experience different evolutionary patterns for their distinct living environments.

  11. Adverse events from spinal manipulation in the pregnant and postpartum periods: a critical review of the literature

    Directory of Open Access Journals (Sweden)

    Stuber Kent

    2012-03-01

    Full Text Available Abstract Background The safety of spinal manipulation during pregnancy and the postpartum periods has been a matter of debate among manual therapists. Spinal manipulative therapy during these periods is a commonly performed intervention as musculoskeletal pain is common in these patients. To date there has not been an evaluation of the literature on this topic exclusively. Methods A literature search was conducted on PubMed, CINAHL and the Index to Chiropractic Literature along with reference searching for articles published in English and French in the peer-reviewed literature that documented adverse effects of spinal manipulation during either pregnancy or postpartum. Case reports, case series, and any other clinical study designs were deemed acceptable for inclusion, as were systematic reviews. The appropriate Scottish Intercollegiate Guidelines Network (SIGN tools were used to rate included articles for quality when applicable. Results Five articles identifying adverse events in seven subjects following spinal manipulation were included in this review, along with two systematic reviews. The articles were published between 1978 and 2009. Two articles describing adverse effects from spinal manipulation on two postpartum patients were included, while the remaining three articles on five patients with adverse effects following spinal manipulation were on pregnant patients. Injury severity ranged from minor injury such as increasing pain after treatment that resolved within a few days to more severe injuries including fracture, stroke, and epidural hematoma. SIGN scores of the prospective observational cohort study and systematic reviews indicated acceptable quality. Conclusions There are only a few reported cases of adverse events following spinal manipulation during pregnancy and the postpartum period identified in the literature. While improved reporting of such events is required in the future, it may be that such injuries are relatively rare.

  12. The risk of river pollution due to washout from contaminated floodplain water bodies during periods of high magnitude floods

    Science.gov (United States)

    Lyubimova, T.; Lepikhin, A.; Parshakova, Ya.; Tiunov, A.

    2016-03-01

    The risk of river pollution due to washout (removal of pollutants) from contaminated floodplain water bodies (floodplain lakes and quarries whose origin is related to the large-scale mining of nonmetallic building materials in the floodplain zone) during high magnitude flood periods is analyzed using a combination of one-, two- and three-dimensional hydrodynamic modeling and in situ measurements. The modeling performed for the floodplain water bodies contaminated by N compounds shows that during large magnitude floods washout occurs. The washout process consists of two stages: an initial rapid stage lasting about two hours during which the upper (3-4 m thick) layer is washed out, followed by a second stage when the concentration of NH4-N in the floodplain water body remains nearly constant. The maximum contaminant concentration in the river in the vicinity of a water intake for drinking water located 21 km downstream is attained about 9 h from the beginning of the flood; concentration of NH4-N can reach values several times larger than acceptable concentration guidelines. The initial primary peak in contaminant concentration at the water intake is followed by a slight decrease in contaminant concentration; a second peak related to the contaminant transport through the inundated floodplain subsequently occurs, after which the concentration slowly decreases, reaching acceptable values after 30-40 h. Contaminated floodplain water bodies located near drinking water supply systems are not significant sources of contamination during small and moderate floods, but during high magnitude floods, they can become sources of water pollution. Operational measures that can decrease potential health risks are discussed.

  13. Can the periodic spectral modulations observed in 236 Sloan Sky Survey stars be due to dark matter effects?

    Science.gov (United States)

    Tamburini, Fabrizio; Licata, Ignazio

    2017-09-01

    The search for dark matter (DM) is one of the most active and challenging areas of current research. Possible DM candidates are ultralight fields such as axions and weak interacting massive particles (WIMPs). Axions piled up in the center of stars are supposed to generate matter/DM configurations with oscillating geometries at a very rapid frequency, which is a multiple of the axion mass m B (Brito et al (2015); Brito et al (2016)). Borra and Trottier (2016) recently found peculiar ultrafast periodic spectral modulations in 236 main sequence stars in the sample of 2.5 million spectra of galactic halo stars of the Sloan Digital Sky Survey (˜1% of main sequence stars in the F-K spectral range) that were interpreted as optical signals from extraterrestrial civilizations, suggesting them as possible candidates for the search for extraterrestrial intelligence (SETI) program. We argue, instead, that this could be the first indirect evidence of bosonic axion-like DM fields inside main sequence stars, with a stable radiative nucleus, where a stable DM core can be hosted. These oscillations were not observed in earlier stellar spectral classes probably because of the impossibility of starting a stable oscillatory regime due to the presence of chaotic motions in their convective nuclei. The axion mass values, (50< {m}B< 2.4× {10}3) μ {eV}, obtained from the frequency range observed by Borra and Trottier, (0.6070< f< 0.6077) THz, agree with the recent theoretical results from high-temperature lattice quantum chromodynamics (Borsanyi et al (2016); Borsanyi et al (2016b)).

  14. Events

    Directory of Open Access Journals (Sweden)

    Igor V. Karyakin

    2016-02-01

    Full Text Available The 9th ARRCN Symposium 2015 was held during 21st–25th October 2015 at the Novotel Hotel, Chumphon, Thailand, one of the most favored travel destinations in Asia. The 10th ARRCN Symposium 2017 will be held during October 2017 in the Davao, Philippines. International Symposium on the Montagu's Harrier (Circus pygargus «The Montagu's Harrier in Europe. Status. Threats. Protection», organized by the environmental organization «Landesbund für Vogelschutz in Bayern e.V.» (LBV was held on November 20-22, 2015 in Germany. The location of this event was the city of Wurzburg in Bavaria.

  15. Lifelong arrhythmic risk stratification in arrhythmogenic right ventricular cardiomyopathy: distribution of events and impact of periodical reassessment.

    Science.gov (United States)

    Cappelletto, Chiara; Stolfo, Davide; De Luca, Antonio; Pinamonti, Bruno; Barbati, Giulia; Pivetta, Alberto; Gobbo, Marco; Brun, Francesca; Merlo, Marco; Sinagra, Gianfranco

    2017-06-13

    The arrhythmic risk stratification of arrhythmogenic right ventricular cardiomyopathy (ARVC) remains controversial. We evaluated the long-term distribution of life-threatening arrhythmic events assessing the impact of periodical risk reassessment. Ninety-eight ARVC patients with no previous major ventricular arrhythmias were retrospectively analysed. Patients were assessed at baseline, at 22 [inter-quartile range (IQR) 16-26], 49 (IQR 41-55) and 97 months (IQR 90-108). The primary endpoint was a composite of sudden cardiac death, ventricular fibrillation, sustained ventricular tachycardia or appropriate implanted cardioverter-defibrillator intervention. During a median follow-up of 91 months (IQR 34-222) 28 patients (29%) experienced the composite endpoint. The median time for the primary event was 35 months (IQR 18-86 months), and 39% of events occurred beyond 49 months of follow-up. History of syncope (HR 4.034; 95% CI, 1.488 to 10.932; P-value = 0.006), non-sustained ventricular tachycardia (NSVT; HR 3.534; 95% CI 1.265-9.877; P-value = 0.016), premature ventricular contractions (PVC) >1000/24h (HR 2.761; 95% CI 1.120-6.807; P-value = 0.027), and right ventricular fractional area change (RVFAC; HR 0.945; 95% CI 0.906-0.985; P-value = 0.008) were found as independent predictors at baseline multivariate analysis. Nevertheless, when the prognostic impact of each variable was reassessed overtime only NSVT (HR 3.282; 95% CI, 1.122 to 9.598, P-value = 0.023) and RVFAC (HR 0.351, 95% CI, 0.157 to 0.780; P-value = 0.010) remained independent predictors throughout the whole follow-up. In our cohort of ARVC patients only NSVT and RVFAC maintained their independent prognostic impact in predicting arrhythmic events during the long-term follow-up. Periodical re-assessment of risk in these patients is strongly recommended.

  16. Characterization And State-Of-The-Art Modeling Of Extreme Precipitation Events Over Africa During The Historical Period

    Science.gov (United States)

    Gibba, P.; Sylla, M. B.

    2015-12-01

    The ability of the state-of-the-art climate models to reproduce the mean spatial characteristics of extreme precipitation indices over Africa is evaluated. The ensembles of eight precipitation-based indices as defined by ETCCDI were extracted from seventeen CMIP5 GCMs and twelve CORDEX RCMs simulations based on absolute and percentile (95th) thresholds and computed from the 1975 to 2004 historical period. Daily precipitation indices calculated from GPCP and TRMM satellite-derived observation datasets during the period 1997 to 2012 and 1998 to 2011 respectively were also employed in this study for model validation. Results of spatial representation of the frequency of extreme precipitation events (R1mm, CDD, CWD and R95p) highlight a generally good consistency between the two observations. Equally, in the regional analysis some similarities exist in their median and interquartile (25th and 75th percentile) spread especially for CDD, CWD and R95p for most regions. In the associated intensities (SDII, RX5day, R95 and R95ptot), results indicate large spatial differences between the two observational datasets, with finer resolution TRMM generating higher rainfall intensities than the coarser resolution GPCP. TRMM has also demonstrated higher median and interquartile range as compared to GPCP. The CORDEX RCMs and CMIP5 GCMs simulations have estimated more number of extreme precipitation events, while underestimated the intensities. The differences between the models and observations can be as large as the typical model interquartile spread of the ensembles for some indices (R1mm, CWD, SDII and R95) in some regions. Meanwhile, CORDEX estimations are generally closer to the observations than CMIP5 in reproducing the frequency of extreme rainfall indices. For the estimation of rainfall intensities, CORDEX simulations are in most cases more consistence with TRMM observations whilst the CMIP5 GCMs simulations are closer to GPCP observations.

  17. Short period airglow temperature and emission rate oscillations in the high Arctic MLT region during stratospheric warming events

    Science.gov (United States)

    Lederman, J. I.

    2015-12-01

    The airglow is a photochemical glow in the upper atmosphere that occurs in thin layers corresponding to different chemical processes. The O2 Atmospheric airglow layer exists at about 94 km altitude and the hydroxyl layer at about 87 km. The intensity of the light gives information about the concentration of atomic oxygen there, while the shape of the spectrum gives accurate values of the temperature. In this investigation, these are measured above Eureka in the Canadian Arctic (80N, 86W) using an instrument called SATI (Spectral Airglow Temperature Imager). The optical data are employed to characterize short period oscillations in rotational temperatures and integral emission rates of OH (6,2) Meinel and O2 (0,1) Atm. bands during a stratospheric warming event from January 2015. In this presentation, SATI observations coupled with wind radiosonde data at Eureka and the ECMWF model are used to compare the January 2015 warming with the major stratospheric warming event of January 2009, thereby providing a window into high frequency atmospheric wave dynamics at play between altitudes of 20 km - 100 km.

  18. Analysis of core damage frequency due to external events at the DOE (Department of Energy) N-Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lambright, J.A.; Bohn, M.P.; Daniel, S.L. (Sandia National Labs., Albuquerque, NM (USA)); Baxter, J.T. (Westinghouse Hanford Co., Richland, WA (USA)); Johnson, J.J.; Ravindra, M.K.; Hashimoto, P.O.; Mraz, M.J.; Tong, W.H.; Conoscente, J.P. (EQE, Inc., San Francisco, CA (USA)); Brosseau, D.A. (ERCE, Inc., Albuquerque, NM (USA))

    1990-11-01

    A complete external events probabilistic risk assessment has been performed for the N-Reactor power plant, making full use of all insights gained during the past ten years' developments in risk assessment methodologies. A detailed screening analysis was performed which showed that all external events had negligible contribution to core damage frequency except fires, seismic events, and external flooding. A limited scope analysis of the external flooding risk indicated that it is not a major risk contributor. Detailed analyses of the fire and seismic risks resulted in total (mean) core damage frequencies of 1.96E-5 and 4.60E-05 per reactor year, respectively. Detailed uncertainty analyses were performed for both fire and seismic risks. These results show that the core damage frequency profile for these events is comparable to that found for existing commercial power plants if proposed fixes are completed as part of the restart program. 108 refs., 85 figs., 80 tabs.

  19. Range expansion of the Bluetongue vector, Culicoides imicola, in continental France likely due to rare wind-transport events.

    Science.gov (United States)

    Jacquet, Stéphanie; Huber, Karine; Pagès, Nonito; Talavera, Sandra; Burgin, Laura E; Carpenter, Simon; Sanders, Christopher; Dicko, Ahmadou H; Djerbal, Mouloud; Goffredo, Maria; Lhor, Youssef; Lucientes, Javier; Miranda-Chueca, Miguel A; Pereira Da Fonseca, Isabel; Ramilo, David W; Setier-Rio, Marie-Laure; Bouyer, Jérémy; Chevillon, Christine; Balenghien, Thomas; Guis, Hélène; Garros, Claire

    2016-06-06

    The role of the northward expansion of Culicoides imicola Kieffer in recent and unprecedented outbreaks of Culicoides-borne arboviruses in southern Europe has been a significant point of contention. We combined entomological surveys, movement simulations of air-borne particles, and population genetics to reconstruct the chain of events that led to a newly colonized French area nestled at the northern foot of the Pyrenees. Simulating the movement of air-borne particles evidenced frequent wind-transport events allowing, within at most 36 hours, the immigration of midges from north-eastern Spain and Balearic Islands, and, as rare events, their immigration from Corsica. Completing the puzzle, population genetic analyses discriminated Corsica as the origin of the new population and identified two successive colonization events within west-Mediterranean basin. Our findings are of considerable importance when trying to understand the invasion of new territories by expanding species.

  20. Mortality due to acute myocardial infarction in China from 1987 to 2014: Secular trends and age-period-cohort effects.

    Science.gov (United States)

    Chang, Jie; Liu, Xin; Sun, Yang

    2017-01-15

    In contrast with most developed countries, mortality from acute myocardial infarction (AMI) continues to rise in China. We examined secular trends and age, period, and cohort effects in mortality from AMI in China from 1987 to 2014. Data on deaths from AMI between 1987 and 2014 were obtained from the Chinese Health Statistics Annual Report (1987-2001) and the Chinese Health Statistics Yearbook (2003-2015). We then conducted an age-period-cohort analysis using the intrinsic estimator approach. There was an upward trend in AMI mortality in both urban and rural populations that accelerated from 2004 onwards. AMI mortality increased 5.6-fold from 1987 to 2014. The net age effect on AMI mortality increased exponentially. AMI mortality risk in the 80-84years of age bracket was 220.15 and 190.70 times higher than in the 15-19years of age bracket in urban and rural populations, respectively. There was a V-shaped trend in the net period effect between 1999 and 2009. Meanwhile, although there was a global reduction in the cohort effect in urban and rural AMI mortality, we found a modest increase among urban populations born between 1975 and 1989 and rural populations born between 1990 and 1999. The changes in exposure to lifestyle-related risk factors and triggers such as air pollution have contributed to the increase in AMI mortality in China over recent decades. The sharp increase in AMI mortality since 2004 is primarily attributable to population aging and the rise in AMI deaths among younger generations. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Bringing Order to Life Events: Memory for the Temporal Order of Autobiographical Events over an Extended Period in School-Aged Children and Adults

    Science.gov (United States)

    Pathman, Thanujeni; Doydum, Ayzit; Bauer, Patricia J.

    2013-01-01

    Remembering temporal information associated with personal past events is critical. Yet little is known about the development of temporal order memory for naturally occurring events. In the current research, 8- to 10-year-old children and adults took photographs daily for 4 weeks. Later, they participated in a primacy/recency task (were shown 2 of…

  2. Log-periodic oscillations and noise-free stochastic multiresonance due to self-similarity of fractals

    CERN Document Server

    Krawiecki, A; Matyjaskiewicz, S; Holyst, J A

    2003-01-01

    The origin of log-periodic oscillations around the power-law trend of the escape probability from a precritical attractor and of the noise-free stochastic multiresonance, found in numerical simulations in chaotic systems close to crises is discussed. It is shown that multiple maxima of the spectral power amplification vs. the control parameter result from a fractal structure of a precritical attractor colliding with a possibly fractal basin of attraction at the crisis point. Qualitative explanation of the multiresonance, based on a concept of fractal self-similarity, or discrete-scale invariance, is given and compared with numerical results and analytic theory using a simple geometric models of the colliding fractal sets.

  3. Lattice Wind Description and Characterization of Mexico City Local Wind Events in the 2001–2006 Period

    Directory of Open Access Journals (Sweden)

    Alejandro Salcido

    2015-07-01

    Full Text Available Urban transformation and expansion in Mexico City continuously affect its urban morphology, and therefore the modes of wind circulation inside it and their occurrence probabilities. Knowledge on these topics is an important issue for urban planning and for other urban studies, such as air quality assessment. In this paper, using a lattice wind model at a meso-β scale, we develop a simple description and characterization of Mexico City local wind events that occurred during the period 2001–2006, including an estimation of the occurrence probabilities. This region was modeled as a 2D lattice domain of identical cells, and wind conditions in each cell were described by four wind attributes: the horizontal velocity components, divergence, and vorticity. Models of one and four cells were applied to wind data furnished by the meteorological network of the city. Results include the following: Early morning: low intensity winds (75% from N, NW, W and SW (75%, convergent (93%, with a slight predominance of cyclonic vorticity (54%. Morning and early afternoon: winds from N, NE and E (72% with speeds from 0.5 to 3.5 m/s, slight prevailing of convergent winds (51%, and slight predominance of cyclonic vorticity (57%. Late afternoon and night: winds blowing from N, NW, and S (63% with speeds from 1.5 to 3.5 m/s (66%, convergent (90%, and cyclonic (72%.

  4. [Analysis of disability due to ocular complications of diabetes in Tashkent over a ten-year period].

    Science.gov (United States)

    Dzhamalova, Sh A; Iskandarova, Sh T; Nabiev, A M

    2016-01-01

    to study peculiarities of primary and recurrent disability due to ocular complications of diabetes in Tashkent over the years 2003-2012 and to assess the impact of risk factors on the effectiveness of laser photocoagulation of the retina. A total of 347 disability examination reports of diabetic patients with ocular complications were copied and 48 case histories of patients with type II diabetes who underwent laser photocoagulation of the retina - retrospectively analyzed. Stabilization of visual function was used as the effectiveness criterion. The rate of new cases of disability over the studied decade averaged 0.55 per 100,000 population per year, while that of recurrent disability was 1.8 times higher - 0.97. The overall rate of disability was not high - 1.53; at that, severe disability (i.e. grade I and II) prevailed. Both recurrent and primary disability groups were made up by middle-aged patients and those in their retirement age; however, in the recurrent disability group the number of young disabled people was 4.5 times higher than in the primary disability group. Studies of the effectiveness of laser photocoagulation of the retina in relation to the compensation of diabetes and blood pressure level showed that unstable general condition was associated with not only significant deterioration of visual function, but also complications, including severe. The rate of disability due to ocular complications of diabetes is generally not high, however, grades I and II disabilities that require greater social support has been found to prevail in both groups. Most of disabled people are middle-aged (working-age population), which also causes economic damage. In cases of decompensated diabetes and unstable blood pressure, the effectiveness of laser photocoagulation of the retina is reduced.

  5. [Hearing loss due to leisure time noise is on the rise. The ear also needs a rest period].

    Science.gov (United States)

    Eggemann, C; Koester, M; Zorowka, P

    2002-12-05

    Noise during leisure time is increasingly leading to temporary and permanent hearing loss, with most victims being adolescents and young adults. Particularly harmful is permanent exposure to noise, since the highly sensitive ear is not designed to tolerate it. On average, youngsters aged between 14 and 20 years spend 3 hours and more listening to music. In discos, concerts in particular, as well as listening to music via headphones, sound levels of 100 dB are regularly reached and exceeded, and levels of 90 dB are already considered to represent a definite risk. Noise is, however, experienced as offensive and painful at levels of about 120-140 dB, and this leads to the danger of its harmful effects being underestimated. Treatment of hearing loss depends on whether it is acute or chronic and comprises infusion therapy, stress reduction, acoustic rest or interposed periods free of noise and, where indicated the fitting of a suitable hearing aid. In view of the immense significance of hearing impairment for the economy, public health, and society at large, its prevention--not only by protective, but also preventive, measures--warrants greater attention.

  6. Adverse Events Due to Chiropractic and Other Manual Therapies for Infants and Children: A Review of the Literature.

    Science.gov (United States)

    Todd, Angela J; Carroll, Matthew T; Robinson, Anske; Mitchell, Eleanor K L

    2015-01-01

    The purpose of this study was to review the literature for cases of adverse events in infants and children treated by chiropractors or other manual therapists, identifying treatment type and if a preexisting pathology was present. English language, peer-reviewed journals and non-peer-reviewed case reports discussing adverse events (ranging from minor to serious) were systematically searched from inception of the relevant searchable bibliographic databases through March 2014. Articles not referring to infants or children were excluded. Thirty-one articles met the selection criteria. A total of 12 articles reporting 15 serious adverse events were found. Three deaths occurred under the care of various providers (1 physical therapist, 1 unknown practitioner, and 1 craniosacral therapist) and 12 serious injuries were reported (7 chiropractors/doctors of chiropractic, 1 medical practitioner, 1 osteopath, 2 physical therapists, and 1 unknown practitioner). High-velocity, extension, and rotational spinal manipulation was reported in most cases, with 1 case involving forcibly applied craniosacral dural tension and another involving use of an adjusting instrument. Underlying preexisting pathology was identified in a majority of the cases. Published cases of serious adverse events in infants and children receiving chiropractic, osteopathic, physiotherapy, or manual medical therapy are rare. The 3 deaths that have been reported were associated with various manual therapists; however, no deaths associated with chiropractic care were found in the literature to date. Because underlying preexisting pathology was associated in a majority of reported cases, performing a thorough history and examination to exclude anatomical or neurologic anomalies before applying any manual therapy may further reduce adverse events across all manual therapy professions. Copyright © 2015 National University of Health Sciences. Published by Elsevier Inc. All rights reserved.

  7. Number Needed to Treat to Harm for Discontinuation Due to Adverse Events in the Treatment of Bipolar Depression, Major Depressive Disorder, and Generalized Anxiety Disorder With Atypical Antipsychotics

    Science.gov (United States)

    Gao, Keming; Kemp, David E.; Fein, Elizabeth; Wang, Zuowei; Fang, Yiru; Ganocy, Stephen J.; Calabrese, Joseph R.

    2012-01-01

    Objective To estimate the number needed to treat to harm (NNTH) for discontinuation due to adverse events with atypical antipsychotics relative to placebo during the treatment of bipolar depression, major depressive disorder (MDD), and generalized anxiety disorder (GAD). Data Sources English-language literature published and cited in MEDLINE from January 1966 to May 2009 was searched with the terms antipsychotic, atypical antipsychotic, generic and brand names of atypical antipsychotics, safety, tolerability, discontinuation due to adverse events, somnolence, sedation, weight gain, akathisia, or extrapyramidal side effect; and bipolar depression, major depressive disorder, or generalized anxiety disorder, and randomized, placebo-controlled clinical trial. This search was augmented with a manual search. Study Selection Studies with a cumulative sample of ≥ 100 patients were included. Data Extraction The NNTHs for discontinuation due to adverse events, somnolence, sedation, ≥ 7% weight gain, and akathisia relative to placebo were estimated with 95% confidence intervals to reflect the magnitude of variance. Data Synthesis Five studies in bipolar depression, 10 studies in MDD, and 4 studies in GAD were identified. Aripiprazole and olanzapine have been studied in bipolar depression and refractory MDD. Only quetiapine extended release (quetiapine-XR) has been studied in 3 psychiatric conditions with different fixed dosing schedules. For aripiprazole, the mean NNTH for discontinuation due to adverse events was 14 in bipolar depression, but was not significantly different from placebo in MDD. For olanzapine, the mean NNTHs were 24 in bipolar depression and 9 in MDD. The risk for discontinuation due to adverse events during quetiapine-XR treatment appeared to be associated with dose. For quetiapine-XR 300 mg/d, the NNTHs for discontinuation due to adverse events were 9 for bipolar depression, 8 for refractory MDD, 9 for MDD, and 5 for GAD. Conclusions At the same dose

  8. Number needed to treat to harm for discontinuation due to adverse events in the treatment of bipolar depression, major depressive disorder, and generalized anxiety disorder with atypical antipsychotics.

    Science.gov (United States)

    Gao, Keming; Kemp, David E; Fein, Elizabeth; Wang, Zuowei; Fang, Yiru; Ganocy, Stephen J; Calabrese, Joseph R

    2011-08-01

    To estimate the number needed to treat to harm (NNTH) for discontinuation due to adverse events with atypical antipsychotics relative to placebo during the treatment of bipolar depression, major depressive disorder (MDD), and generalized anxiety disorder (GAD). English-language literature published and cited in MEDLINE from January 1966 to May 2009 was searched with the terms antipsychotic, atypical antipsychotic, generic and brand names of atypical antipsychotics, safety, tolerability, discontinuation due to adverse events, somnolence, sedation, weight gain, akathisia, or extrapyramidal side effect; and bipolar depression, major depressive disorder, or generalized anxiety disorder; and randomized, placebo-controlled clinical trial. This search was augmented with a manual search. Studies with a cumulative sample of ≥ 100 patients were included. The NNTHs for discontinuation due to adverse events, somnolence, sedation, ≥ 7% weight gain, and akathisia relative to placebo were estimated with 95% confidence intervals to reflect the magnitude of variance. Five studies in bipolar depression, 10 studies in MDD, and 4 studies in GAD were identified. Aripiprazole and olanzapine have been studied in bipolar depression and refractory MDD. Only quetiapine extended release (quetiapine-XR) has been studied in 3 psychiatric conditions with different fixed dosing schedules. For aripiprazole, the mean NNTH for discontinuation due to adverse events was 14 in bipolar depression, but was not significantly different from placebo in MDD. For olanzapine, the mean NNTHs were 24 in bipolar depression and 9 in MDD. The risk for discontinuation due to adverse events during quetiapine-XR treatment appeared to be associated with dose. For quetiapine-XR 300 mg/d, the NNTHs for discontinuation due to adverse events were 9 for bipolar depression, 8 for refractory MDD, 9 for MDD, and 5 for GAD. At the same dose of quetiapine-XR, patients with GAD appeared to have a lower tolerability than

  9. Events at blood collection area due to nonconforming blood bags and plateletpheresis kits: need for timely corrective and preventive actions.

    Science.gov (United States)

    Verma, Anupam; Sachan, Deepti; Elhence, Priti; Pandey, Hem; Dubey, Anju

    2012-07-01

    Good blood banking practice requires that every effort should be made to detect any deviation or defect in blood bank products and to identify any potential risk to blood donor or recipient(s). We report the findings of an exercise that provide an insight into why feedback from the user side is crucial. Various events involving blood bags and plateletpheresis kits and the corresponding appropriate actions instituted for remedial measures were recorded. These scattered events were recorded for 6 months following the use of a new batch of improved blood bags with add-on features. Several events related to plateletpheresis kits from three different manufacturers were also recorded for 1 year. The affected blood bags were utilized with no untoward incident. The complaint was closed following satisfactory response from the blood bag manufacturing company that acted in a timely manner in addressing the root causes of the problems. However, corrective and preventive actions (CAPA) could not be implemented for plateletpheresis kits. The rate of undesirable events was higher with plateletpheresis kits as compared with whole blood bags (1.75% vs. 0.06%). As defects or deviations that trigger the need for CAPA can stem from numerous sources, it is important to clearly identify and document the problems and level of risk so that appropriate investigations can be instituted and remedial actions can be taken in a timely manner. This study demonstrates the usefulness of a quality initiative to collate and analyze blood product faults in conjunction with blood product manufacturers. © 2012 American Association of Blood Banks.

  10. The impact of the lookback period and definition of confirmatory events on the identification of incident cancer cases in administrative data.

    Science.gov (United States)

    Czwikla, Jonas; Jobski, Kathrin; Schink, Tania

    2017-08-14

    This cohort study examined the impact of the lengths of lookback and confirmation periods as well as the definition of confirmatory events on the number of incident cancer cases identified and age-standardized cumulative incidences (ACI) estimated in administrative data using German cancer registry data as a benchmark. ACI per 100,000 insured persons for breast, prostate and colorectal cancer were estimated using BARMER Statutory Health Insurance claims data. Incident cancer cases were defined as having an in- or outpatient diagnosis in 2013, no diagnosis in a lookback period of 1 year and a second diagnosis (or death) in a confirmation period of 1 quarter. We varied lookback periods from 1 to 7 years, confirmation periods from 1 to 4 quarters as well as the definition of confirmatory events and compared ACI estimates to cancer registry data. ACI were higher for breast (138.7) and prostate (103.6) but lower for colorectal cancer (42.1) when compared to cancer registries (119.3, 98.0 and 45.5, respectively). Extending the lookback period to 7 years reduced ACI to 129.0, 95.1 and 38.3. An extended confirmation period of 4 quarters increased ACI to 151.3, 114.9 and 46.8. Including breast and colorectal surgeries as a confirmatory event reduced ACI to 114.9 and 37.1, respectively. The choice of lookback and confirmation periods and the definition of confirmatory events have considerable impact on the number of incident cancer cases identified and ACI estimated. Researchers need to be aware of potential misclassification when identifying incident cancer cases in administrative data. Further validation studies as well as studies using administrative data to estimate cancer incidences should consider several choices of the lookback and confirmation periods and the definition of confirmatory events to show how these parameters impact the validity and robustness of their results.

  11. DUE AvalRS: Remote Sensing Derive Avalanche Inventory Data for Decision Support and Hind-Cast After Avalanche Events

    Science.gov (United States)

    Frauenfelder, Regula; Kronholm, Kalle; Solberg, Rune; Larsen, Siri Oyen; Salberg, Arnt-Borre; Larsen, Jan Otto; Bjordal, Heidi

    2010-12-01

    Each year, snow avalanches hit populated areas and parts of the transport network in the Norwegian mountain regions, leading to loss of lives and the damaging of buildings and infrastructure. We present the results of a feasibility study on the operation of a service providing the National Public Roads Administration (NPRA) with hind-cast avalanche inventory data on a local-to-regional scale during the course of the winter season, and as soon as possible after major avalanche events. We have explored the use of imagery from high-resolution and very-high-resolution space-borne satellites applying manual mapping and automated image segmentation.

  12. Multi-Model Simulations of Aerosol and Ozone Radiative Forcing Due to Anthropogenic Emission Changes During the Period 1990-2015

    Science.gov (United States)

    Myhre, Gunnar; Aas, Wenche; Ribu, Cherian; Collins, William; Faluvegi, Gregory S.; Flanner, Mark; Forster, Piers; Hodnebrog, Oivind; Klimont, Zbigniew; Lund, Marianne T.

    2017-01-01

    Over the past few decades, the geographical distribution of emissions of substances that alter the atmospheric energy balance has changed due to economic growth and air pollution regulations. Here, we show the resulting changes to aerosol and ozone abundances and their radiative forcing using recently updated emission data for the period 1990-2015, as simulated by seven global atmospheric composition models. The models broadly reproduce large-scale changes in surface aerosol and ozone based on observations (e.g. 1 to 3 percent per year in aerosols over the USA and Europe). The global mean radiative forcing due to ozone and aerosol changes over the 1990-2015 period increased by 0.17 plus or minus 0.08 watts per square meter, with approximately one-third due to ozone. This increase is more strongly positive than that reported in IPCC AR5 (Intergovernmental Panel on Climate Change Fifth Assessment Report). The main reasons for the increased positive radiative forcing of aerosols over this period are the substantial reduction of global mean SO2 emissions, which is stronger in the new emission inventory compared to that used in the IPCC analysis, and higher black carbon emissions.

  13. Multi-model simulations of aerosol and ozone radiative forcing due to anthropogenic emission changes during the period 1990-2015

    Science.gov (United States)

    Myhre, Gunnar; Aas, Wenche; Cherian, Ribu; Collins, William; Faluvegi, Greg; Flanner, Mark; Forster, Piers; Hodnebrog, Øivind; Klimont, Zbigniew; Lund, Marianne T.; Mülmenstädt, Johannes; Myhre, Cathrine Lund; Olivié, Dirk; Prather, Michael; Quaas, Johannes; Samset, Bjørn H.; Schnell, Jordan L.; Schulz, Michael; Shindell, Drew; Skeie, Ragnhild B.; Takemura, Toshihiko; Tsyro, Svetlana

    2017-02-01

    Over the past few decades, the geographical distribution of emissions of substances that alter the atmospheric energy balance has changed due to economic growth and air pollution regulations. Here, we show the resulting changes to aerosol and ozone abundances and their radiative forcing using recently updated emission data for the period 1990-2015, as simulated by seven global atmospheric composition models. The models broadly reproduce large-scale changes in surface aerosol and ozone based on observations (e.g. -1 to -3 % yr-1 in aerosols over the USA and Europe). The global mean radiative forcing due to ozone and aerosol changes over the 1990-2015 period increased by +0.17 ± 0.08 W m-2, with approximately one-third due to ozone. This increase is more strongly positive than that reported in IPCC AR5. The main reasons for the increased positive radiative forcing of aerosols over this period are the substantial reduction of global mean SO2 emissions, which is stronger in the new emission inventory compared to that used in the IPCC analysis, and higher black carbon emissions.

  14. Multi-model simulations of aerosol and ozone radiative forcing due to anthropogenic emission changes during the period 1990-2015

    Science.gov (United States)

    Myhre, Gunnar

    2017-04-01

    Over the past decades, the geographical distribution of emissions of substances that alter the atmospheric energy balance has changed due to economic growth and pollution regulations. Here, we show the resulting changes to aerosol and ozone abundances and their radiative forcing, using recently updated emission data for the period 1990-2015, as simulated by seven global atmospheric composition models. The models broadly reproduce large-scale changes in surface aerosol and ozone based on observations (e.g., -1 to -3%/yr in aerosols over the US and Europe). The global mean radiative forcing due to ozone and aerosols changes over the 1990-2015 period increased by +0.17 ±0.08 Wm-2, with approximately 1/3 due to ozone. This increase is more strongly positive than reported in IPCC AR5. The main reasons for the increased positive radiative forcing of aerosols over this period are the substantial reduction of global mean SO2 emissions, which is stronger in the new emission inventory compared to the IPCC, and higher black carbon emissions.

  15. Can the 62 Day X-ray Period of ULX M82 X-1 Be Due to a Precessing Accretion Disk?

    Science.gov (United States)

    Pasham, Dheeraj R.; Strohmayer, Tod E.

    2013-01-01

    We have analyzed all the archival RXTE/PCA monitoring observations of the ultraluminous X-ray source (ULX) M82 X-1 in order to study the properties of its previously discovered 62 day X-ray period (Kaaret & Feng 2007). Based on the high coherence of the modulation it has been argued that the observed period is the orbital period of the binary. Utilizing a much longer data set than in previous studies we find: (1) The phase-resolved X-ray (3-15 keV) energy spectra - modeled with a thermal accretion disk and a power-law corona - suggest that the accretion disk's contribution to the total flux is responsible for the overall periodic modulation while the power-law flux remains approximately constant with phase. (2) Suggestive evidence for a sudden phase shift-of approximately 0.3 in phase (20 days)-between the first and the second halves of the light curve separated by roughly 1000 days. If confirmed, the implied timescale to change the period is approx. = 10 yrs, which is exceptionally fast for an orbital phenomenon. These independent pieces of evidence are consistent with the 62 day period being due to a precessing accretion disk, similar to the so-called super-orbital periods observed in systems like Her X-1, LMC X-4, and SS433. However, the timing evidence for a change in the period needs to be confirmed with additional observations. This should be possible with further monitoring of M82 with instruments such as the X-ray telescope (XRT) on board Swift.

  16. Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study.

    Directory of Open Access Journals (Sweden)

    Xiao Jin

    Full Text Available To investigate response inhibition after total sleep deprivation (TSD and the restorative effects of one night of recovery sleep (RS.Fourteen healthy male participants performed a visual Go/NoGo task, and electroencephalogram recordings were conducted at five time points: (1 baseline, (2 after 12 h of TSD, (3 after 24 h of TSD, (4 after 36 h of TSD, and (5 following 8 h of RS. The dynamic changes in response inhibition during TSD and after 8 h of RS were investigated by examining the NoGo-N2 and NoGo-P3 event-related potential components.Compared with baseline, NoGo-P3 amplitudes were decreased, while the NoGo-N2 latency increased along with the awake time prolonged. NoGo anteriorization, which was minimized after 24 h of TSD, progressively decreased with increasing TSD. After 8 h of RS, recoveries of both the NoGo-P3 amplitude and NoGo-N2 latency in the prefrontal cortex were observed compared with the values after 36 h of TSD.TSD induced a dose-dependent functional decline in the response inhibition of NoGo-N2 and NoGo-P3 on prefrontal cortex activation, and 8 h of RS resulted in recovery or maintenance of the response inhibition. However, it was not restored to baseline levels.Participants were chosen male college students only, thus the findings cannot be generalized to older people and women. Additionally, the sample size was small, and, thus, speculations on the meaning of the results of this study should be cautious. The EEG continuous recording should be employed to monitor the decline of alertness following TSD.

  17. Recovery Sleep Reverses Impaired Response Inhibition due to Sleep Restriction: Evidence from a Visual Event Related Potentials Study.

    Science.gov (United States)

    Jin, Xiao; Ye, Enmao; Qi, Jianlin; Wang, Lubin; Lei, Yu; Chen, Pinhong; Mi, Guiyun; Zou, Feng; Shao, Yongcong; Yang, Zheng

    2015-01-01

    To investigate response inhibition after total sleep deprivation (TSD) and the restorative effects of one night of recovery sleep (RS). Fourteen healthy male participants performed a visual Go/NoGo task, and electroencephalogram recordings were conducted at five time points: (1) baseline, (2) after 12 h of TSD, (3) after 24 h of TSD, (4) after 36 h of TSD, and (5) following 8 h of RS. The dynamic changes in response inhibition during TSD and after 8 h of RS were investigated by examining the NoGo-N2 and NoGo-P3 event-related potential components. Compared with baseline, NoGo-P3 amplitudes were decreased, while the NoGo-N2 latency increased along with the awake time prolonged. NoGo anteriorization, which was minimized after 24 h of TSD, progressively decreased with increasing TSD. After 8 h of RS, recoveries of both the NoGo-P3 amplitude and NoGo-N2 latency in the prefrontal cortex were observed compared with the values after 36 h of TSD. TSD induced a dose-dependent functional decline in the response inhibition of NoGo-N2 and NoGo-P3 on prefrontal cortex activation, and 8 h of RS resulted in recovery or maintenance of the response inhibition. However, it was not restored to baseline levels. Participants were chosen male college students only, thus the findings cannot be generalized to older people and women. Additionally, the sample size was small, and, thus, speculations on the meaning of the results of this study should be cautious. The EEG continuous recording should be employed to monitor the decline of alertness following TSD.

  18. Surface Deformation Due to the May 27, 1995 Sakhalin Earthquake and Related Events Measured by JERS-1 SAR Interferometry

    Science.gov (United States)

    Fielding, E. J.; Fujiwara, Satoshi; Hensley, S.; Rosen, P. A.; Tobita, Mikio; Shimada, Masanobu

    1996-01-01

    A large (M&subw;=7.0) earthquake on May 27, 1995 completely destroyed the town of Neftegorsk in the northern part of Sakhalin Island and caused more than 2000 human deaths. The shallow, right-lateral, strick-slip earthquake resulted in extensive surface ruptures and up to 7 m of horizontal displacement as reported by field workers. The sourthern part of the mainshock epicenter zone was imaged by the JERS-1 SAR (synthetic aperature radar) one month (April 28) before and two weeks after (June 11) the mainshock. Despite drastically changed surface conditions in the 44 days between the two images, due primarily to spring thaw, we obtained reasonably good interferometric correlation with the L-band (24 cm) SAR pair. The interoferogram records the distribution of deformation reflecting displacement during both the mainshock and aftershocks. The ability to map the deformation pattern can aid the assessment and mitigation of damage.

  19. ICUD-0147 Extreme event statistics of urban pluvial floods – Return period assessment and rainfall variability impacts

    DEFF Research Database (Denmark)

    Tuyls, Damian Murla; Nielsen, Rasmus; Thorndahl, Søren Liedtke

    2017-01-01

    A return period assessment of urban flood has been performed and its adhered impact of rainfall variability studied over a urban drainage catchment area in Aalborg, Denmark. Recorded rainfall from 7 rain gauges has been used, located in a range of 7.5Km and for a period varying form 18-37 years....... Return period of rainfall and flood at catchment and local scale has been estimated, its derived ambiguities analysed and the variability of rain gauge based rainfall investigated regarding to flood estimation results. Results show a clear contrast between rainfall and flood return period estimates...

  20. Event-Related Potentials (ERPs) in Second Language Research: A Brief Introduction to the Technique, a Selected Review, and an Invitation to Reconsider Critical Periods in L2

    Science.gov (United States)

    Steinhauer, Karsten

    2014-01-01

    This article provides a selective overview of recent event-related brain potential (ERP) studies in L2 morpho-syntax, demonstrating that the ERP evidence supporting the critical period hypothesis (CPH) may be less compelling than previously thought. The article starts with a general introduction to ERP methodology and language-related ERP profiles…

  1. Probability assessment for the incidence of extreme events due to the climatic change. Focus Germany; Berechnung der Wahrscheinlichkeiten fuer das Eintreten von Extremereignissen durch Klimaaenderungen. Schwerpunkt Deutschland

    Energy Technology Data Exchange (ETDEWEB)

    Jonas, Martin; Staeger, Tim; Schoenwiese, Christian-Dietrich [Frankfurt Univ. (Germany). Inst. fuer Atmosphaere und Umwelt, Arbeitsgruppe Klimaforschung

    2005-08-15

    The study on the probability of occurrence of extreme weather events in Germany is based on compiled data covering ground-level temperature, precipitation and wind during the time period 1901 to 2000. The data processing approach is based on two methodologies: a time-gliding extreme value analysis and a structure-oriented time-series analysis. The results show a significant increase of very hot months and at the same time a decrease of extreme cold months within the 20th century. In the time period after 1951 the probability of very high daily maximum temperatures increased for all seasons. Concerning the precipitation the increase of extreme values and higher variabilities are observed for the winter period. The results concerning the wind are not so clear. Summarizing the extreme behavior of temperature and precipitation has shown strong variations during the last century.

  2. Effect of plasma density on diffusion rates due to wave particle interactions with chorus and plasmaspheric hiss: extreme event analysis

    Directory of Open Access Journals (Sweden)

    A. Sicard-Piet

    2014-08-01

    Full Text Available Wave particle interactions play an important role in controlling the dynamics of the radiation belts. The purpose of this study is to estimate how variations in the plasma density can affect diffusion rates resulting from interactions between chorus waves and plasmaspheric hiss with energetic particles and the resulting evolution of the energetic electron population. We perform a statistical analysis of the electron density derived from the plasma wave experiment on the CRRES satellite for two magnetic local time sectors corresponding to near midnight and near noon. We present the cumulative probability distribution of the electron plasma density for three levels of magnetic activity as measured by Kp. The largest densities are seen near L* = 2.5 while the smallest occur near L* = 6. The broadest distribution, corresponding to the greatest variability, occurs near L* = 4. We calculate diffusion coefficients for plasmaspheric hiss and whistler mode chorus for extreme values of the electron density and estimate the effects on the radiation belts using the Salammbô model. At L* = 4 and L* = 6, in the low density case, using the density from the 5th percentile of the cumulative distribution function, electron energy diffusion by chorus waves is strongest at 2 MeV and increases the flux by up to 3 orders of magnitude over a period of 24 h. In contrast, in the high density case, using the density from the 95th percentile, there is little acceleration at energies above 800 keV at L* = 6, and virtually no acceleration at L* = 4. In this case the strongest energy diffusion occurs at lower energies around 400 keV where the flux at L* = 6 increases 3 orders of magnitude.

  3. Effect of plasma density on diffusion rates due to wave particle interactions with chorus and plasmaspheric hiss: extreme event analysis

    Science.gov (United States)

    Sicard-Piet, A.; Boscher, D.; Horne, R. B.; Meredith, N. P.; Maget, V.

    2014-08-01

    Wave particle interactions play an important role in controlling the dynamics of the radiation belts. The purpose of this study is to estimate how variations in the plasma density can affect diffusion rates resulting from interactions between chorus waves and plasmaspheric hiss with energetic particles and the resulting evolution of the energetic electron population. We perform a statistical analysis of the electron density derived from the plasma wave experiment on the CRRES satellite for two magnetic local time sectors corresponding to near midnight and near noon. We present the cumulative probability distribution of the electron plasma density for three levels of magnetic activity as measured by Kp. The largest densities are seen near L* = 2.5 while the smallest occur near L* = 6. The broadest distribution, corresponding to the greatest variability, occurs near L* = 4. We calculate diffusion coefficients for plasmaspheric hiss and whistler mode chorus for extreme values of the electron density and estimate the effects on the radiation belts using the Salammbô model. At L* = 4 and L* = 6, in the low density case, using the density from the 5th percentile of the cumulative distribution function, electron energy diffusion by chorus waves is strongest at 2 MeV and increases the flux by up to 3 orders of magnitude over a period of 24 h. In contrast, in the high density case, using the density from the 95th percentile, there is little acceleration at energies above 800 keV at L* = 6, and virtually no acceleration at L* = 4. In this case the strongest energy diffusion occurs at lower energies around 400 keV where the flux at L* = 6 increases 3 orders of magnitude.

  4. [Health damage assessment due to PM2.5 exposure during haze pollution events in Beijing-Tianjin-Hebei region in January 2013].

    Science.gov (United States)

    Zhang, Yan-shen; Ma, Guo-xia; Yu, Fang; Cao, Dong

    2013-09-10

    To assess the human health damage due to particulate matter ≤ 2.5 µm (PM2.5) exposure during the haze pollution events in 12 cities of Beijing-Tianjin-Hebei region in January 2013. The data were collected for urban population, ambient air quality, baseline mortality rate and emergency visits in Beijing, Tianjin, Shijiazhuang, Baoding, Chengde, Handan, Langfang, Hengshui, Qinhuangdao, Tangshan, Xingtai and Zhangjiakou. Then the exposure-response relationship was constructed between short-term PM2.5 exposure and mortality and emergency room visits with meta-analysis. Thus the excess deaths and emergency room visits due to PM2.5 exposure were estimated during the haze pollution events using city-specific exposure population, PM2.5 daily concentration and exposure-response coefficients. Three serious PM2.5 pollution events occurred on January 12, January 19 and January 27 in Beijing-Tianjin-Hebei region respectively. From January 10 to January 31, the 24 h mean concentrations of PM2.5 in Beijing, Tianjin, Shijiazhuang, Tangshan, Qinhuangdao, Handan, Xingtai, Baoding, Zhangjiakou, Chengde, Langfang, Hengshui were 705, 411, 675, 506, 255, 598, 698, 667, 231, 178, 718 and 405 µg/m(3). Xingtai, Shijiazhuang, Handan, Baoding, Langfang and Beijing were the more polluted areas. And there were 17 days (77.3%), 13 days (59.1%), 12 days (54.5%), 11 days (50.0%), 10 days (45.5%) and 8 days (36.4%) of Air Quality Index reaching the serious level respectively. The short-term PM2.5 exposure caused 2725 excess death including 846 excess deaths duo to respiratory disease and 1878 excess deaths due to circulatory disease in Beijing-Tianjin-Hebei region from January 10 to January 31. The haze pollution events led to serious public health damage. And it is imperative to take actions of controlling PM2.5 pollution.

  5. Evaluation of the Expression Profile of Extrapyramidal Symptoms Due to Antipsychotics by Data Mining of Japanese Adverse Drug Event Report (JADER) Database.

    Science.gov (United States)

    Kose, Eiji; Uno, Kana; Hayashi, Hiroyuki

    2017-01-01

     Typical antipsychotics are easily expressed as adverse events such as extrapyramidal symptom (EPS). On the other hand, incidence of adverse events due to atypical antipsychotics is low. Therefore, currently, atypical antipsychotics are widely used to treat schizophrenia. However, it has been reported that there is no difference in the frequency of EPS in atypical and typical antipsychotics. This study aimed to evaluate the expression profile of EPS in atypical and typical antipsychotics treatment using the Japanese Adverse Drug Event Report (JADER) database. We analyzed reports of EPS in the JADER database and calculated the reporting odds ratio (ROR) of antipsychotics potentially associated with EPS. We applied the Weibull shape parameter to time-to-event data in the JADER database. Consequently, there was little information to distinguish between the ROR of atypical and typical antipsychotics. A significant difference related to the time of onset of EPS in both antipsychotics was not recognized. However, when comparing each drug, Paliperidone, Perospirone, Blonanserin, and Aripiprazole were relatively developed as EPS in the early stage. On the other hand, Risperidone, Clozapine, Olanzapine, and Quetiapine were developed as EPS not only at an early stage but also after long-term use. In addition, this finding was suggested from the result of the cumulative incidence of EPS in each drug and of the time-to-onset analysis using Weibull distribution. These findings may contribute to future clinical practice because we revealed the expression profile of EPS in treatment with atypical and typical antipsychotics.

  6. Apparent Life-Threatening Events in Neonatal Period: Clinical Manifestations and Diagnostic Challenges in a Pediatric Referral Center

    OpenAIRE

    Kadivar, Maliheh; Yaghmaie, Bahareh; Allahverdi, Bahar; Shahbaznejad, Leila; Razi, Nosrat; Mosayebi, Ziba

    2013-01-01

    Objective Apparent Life-Threatening Events (ALTEs) is an episode that is frightening to the observer and is characterized by some combination of apnea, color change, altered muscle tone, choking, and gagging. This study was designed to evaluate and follow up neonates who presented with clinical manifestation of an ALTE in a year. Methods In this prospective observational study, all of the neonates with episode of ALTE who were admitted to the Children's Medical Center (CMC) in Tehran, from Ju...

  7. Retrospective evaluation of all recorded horse race starts in Switzerland during a four year period focusing on discipline-specific risk factors for clinical events.

    Science.gov (United States)

    Schweizer, C; Ramseyer, A; Gerber, V; Christen, G; Burger, D; Wohlfender, F D

    2016-11-01

    Racetrack injuries are of welfare concern and the prevention of injuries is an important goal in many racing jurisdictions. Over the years this has led to more detailed recording of clinical events on racecourses. However, risk factor analyses of clinical events at race meetings have not been previously reported for Switzerland. To identify discipline-specific factors that influence the occurrence of clinical events during race meetings with the ultimate aim of improving the monitoring and safety of racetracks in Switzerland and optimising racehorse welfare. Retrospective study of horse race data collected by the Swiss horse racing association. All race starts (n = 17,670, including 6198 flat, 1257 obstacle and 10,215 trot race starts) recorded over a period of 4 years (2009-2012) were analysed in multivariable mixed effect logistic regression models including horse and racecourse related data. The models were designed to identify discipline-specific factors influencing the occurrence of clinical events on racecourses in Switzerland. Factors influencing the risk of clinical events during races were different for each discipline. The risk of a clinical event in trot racing was lower for racing on a Porphyre sand track than on grass tracks. Horses whose driver was also their trainer had an approximately 2-fold higher risk for clinical events. In obstacle races, longer distances (2401-3300 m and 3301-5400 m, respectively) had a protective effect compared with racing over shorter distances. In flat racing, 5 racecourses reported significantly fewer clinical events. In all 3 disciplines, finishing 8th place or later was associated with clinical events. Changes in management that aim to improve the safety and welfare of racehorses, such as racetrack adaptations, need to be individualised for each discipline. © 2015 EVJ Ltd.

  8. Effect of Severity of Esophageal Acidification on Sleep vs Wake Periods in Infants Presenting with Brief Resolved Unexplained Events.

    Science.gov (United States)

    Sankaran, Janani; Qureshi, Aslam H; Woodley, Frederick; Splaingard, Mark; Jadcherla, Sudarshan R

    2016-12-01

    To describe the pattern of gastroesophageal reflux (GER) events in wake and sleep states with increasing acid reflux index (ARI) in neonates and to test the hypothesis that GER-related symptoms are frequent in ARI >7% in wake state. Infants underwent 24-hour pH-impedance studies with 6-hour concurrent video-polysomnography studies. Data were stratified based on the 24-hour ARI (% duration that esophageal pH is 7% (abnormal). GER frequency, clearance mechanisms, and symptoms were distinguished during wake state and sleep state. Total wake and sleep duration was similar (P ≥ .2) in all ARI groups. Acidic events were frequent with increasing ARI in wake state vs sleep state (P ≤ .03). The symptom index increased with increasing ARI (P ≤ .02) in both wake state and sleep state. Acid clearance time increased with increasing ARI in wake state (P ≤ .02). In ARI > 7% vs ARI ≤ 7%, frequency of acidic GER events was higher (P ≤ .02) in wake state and sleep state; proximal migration of acid (P = .03) and acid clearance time were higher in wake state (P = .0005) only. Symptom index was higher in ARI >7% vs ARI ≤ 7% in wake state (P 7%) is associated with increased reflux-associated symptoms in wake state. Sleep state appears to be protective regardless of ARI, likely because of greater chemosensory thresholds. Attention to posture and movements during wake state can be helpful. Scrutiny for non-GER etiologies should occur for infants presenting with life-threatening symptoms. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. 2013 Immune Risk Standing Review Panel Evidence Review for: The Risk of Crew Adverse Health Event Due to Altered Immune Response

    Science.gov (United States)

    Steinberg, Susan

    2014-01-01

    The 2013 Immune Risk Standing Review Panel (from here on referred to as the SRP) met for a site visit in Houston, TX on February 3-4, 2014. The SRP reviewed the new Evidence Report for the Risk of Crew Adverse Health Event Due to Altered Immune Response (from here on referred to as the 2013 Immune Evidence Report), as well as the Research Plan for this Risk that is in the current version of the Human Research Program’s (HRP) Integrated Research Plan (IRP).

  10. An attempt to estimate the economic value of the loss of human life due to landslide and flood events in Italy

    Science.gov (United States)

    Salvati, Paola; Bianchi, Cinzia; Hussin, Haydar; Guzzetti, Fausto

    2013-04-01

    Landslide and flood events in Italy cause wide and severe damage to buildings and infrastructure, and are frequently involved in the loss of human life. The cost estimates of past natural disasters generally refer to the amount of public money used for the restoration of the direct damage, and most commonly do not account for all disaster impacts. Other cost components, including indirect losses, are difficult to quantify and, among these, the cost of human lives. The value of specific human life can be identified with the value of a statistical life (VLS), defined as the value that an individual places on a marginal change in their likelihood of death This is different from the value of an actual life. Based on information of fatal car accidents in Italy, we evaluate the cost that society suffers for the loss of life due to landslide and flood events. Using a catalogue of fatal landslide and flood events, for which information about gender and age of the fatalities is known, we determine the cost that society suffers for the loss of their life. For the purpose, we calculate the economic value in terms of the total income that the working-age population involved in the fatal events would have earned over the course of their life. For the computation, we use the pro-capita income calculated as the ratio between the GDP and the population value in Italy for each year, since 1980. Problems occur for children and retired people that we decided not to include in our estimates.

  11. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods

    Science.gov (United States)

    Edwards, Christopher L.; Malinowski, Josie E.; McGee, Shauna L.; Bennett, Paul D.; Ruby, Perrine M.; Blagrove, Mark T.

    2015-01-01

    There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on rapid eye movement (REM) sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, one male) reported and considered a recent home dream in a dream discussion group that following the “Appreciating dreams” method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (seven females, two males) reported and considered a recent home dream in a group that followed the “Listening to the dreamer” method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation (GDI) scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method Exploration-Insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and non-REM dream reports, hypothesizing greater

  12. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods

    Directory of Open Access Journals (Sweden)

    Christopher Lloyd Edwards

    2015-06-01

    Full Text Available There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on Rapid Eye Movement sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, 1 male reported and considered a recent home dream in a dream discussion group that following the ‘Appreciating dreams’ method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (7 females, 2 males reported and considered a recent home dream in a group that followed the ‘Listening to the dreamer’ method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method exploration-insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and NREM dream reports, hypothesizing greater

  13. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods.

    Science.gov (United States)

    Edwards, Christopher L; Malinowski, Josie E; McGee, Shauna L; Bennett, Paul D; Ruby, Perrine M; Blagrove, Mark T

    2015-01-01

    There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on rapid eye movement (REM) sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, one male) reported and considered a recent home dream in a dream discussion group that following the "Appreciating dreams" method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (seven females, two males) reported and considered a recent home dream in a group that followed the "Listening to the dreamer" method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation (GDI) scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method Exploration-Insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and non-REM dream reports, hypothesizing greater insight

  14. Novel analysis of sleep patterns in rats separates periods of vigilance cycling from long-duration wake events.

    Science.gov (United States)

    Simasko, Steven M; Mukherjee, Sanjib

    2009-01-23

    Rats are polyphasic sleepers. However, a formal definition of when one sleep episode ends and another begins has not been put forth. In the present study we examine the distribution of wake episode durations and based on this distribution conclude there are multiple components of wake. If the wake episode exceeds 300 s the wake episode is assigned to long-duration wake (LDW), if the episode is less than 300 s it is assigned to brief wake (BW). Further support for this separation was found in close analysis of the EEG power spectrum in BW versus LDW. We then used LDW episodes to separate one sleep episode from another. We term the sleep episodes vigilance cycling (VC) because the rat is cycling between the vigilance states of BW, slow-wave sleep (SWS), and rapid-eye movement sleep (REMS). We find that the characteristics of VC are different in the light period versus the dark period. We further find that as VC episodes progress, SWS pressure lessens, but the amount of time spent in REMS increases. These findings suggest that VC episodes are regulated and meaningful to the sleep behavior of rats. The use of the concepts of LDW and VC provides additional insights into the description of sleep patterns in rats that may be important in the development of a complete description of sleep behavior in this animal.

  15. Probability Estimates of Solar Particle Event Doses During a Period of Low Sunspot Number for Thinly-Shielded Spacecraft and Short Duration Missions

    Science.gov (United States)

    Atwell, William; Tylka, Allan J.; Dietrich, William; Rojdev, Kristina; Matzkind, Courtney

    2016-01-01

    In an earlier paper (Atwell, et al., 2015), we investigated solar particle event (SPE) radiation exposures (absorbed dose) to small, thinly-shielded spacecraft during a period when the sunspot number (SSN) was less than 30. These SPEs contain Ground Level Events (GLE), sub-GLEs, and sub-sub-GLEs (Tylka and Dietrich, 2009, Tylka and Dietrich, 2008, and Atwell, et al., 2008). GLEs are extremely energetic solar particle events having proton energies extending into the several GeV range and producing secondary particles in the atmosphere, mostly neutrons, observed with ground station neutron monitors. Sub-GLE events are less energetic, extending into the several hundred MeV range, but do not produce secondary atmospheric particles. Sub-sub GLEs are even less energetic with an observable increase in protons at energies greater than 30 MeV, but no observable proton flux above 300 MeV. In this paper, we consider those SPEs that occurred during 1973-2010 when the SSN was greater than 30 but less than 50. In addition, we provide probability estimates of absorbed dose based on mission duration with a 95% confidence level (CL). We also discuss the implications of these data and provide some recommendations that may be useful to spacecraft designers of these smaller spacecraft.

  16. Associations between recreational runners' anti-inflammatory drug use, coping strategies, and time loss due to injury and illness during preparations for a marathon event.

    Science.gov (United States)

    Tillander, Bo; Gauffin, Håkan; Dahlström, Örjan; Timpka, Toomas

    2018-01-04

    Due to the dominance of overuse injuries among runners, knowledge of how use of non-steroidal anti-inflammatory drugs (NSAIDs) and behavioural factors contribute to injury events is important. The aim of this study was to explore recreational marathon runners' strategies for coping with injury and illness, including use of drugs for control of pain and inflammation, and to investigate whether these strategies were associated with the 1-year prevalence of time-loss injury and illness. An online questionnaire was used for data collection in this cross-sectional study. The population consisted of runners who had registered for a marathon (n=341). Strategies used to understand and manage perceptions of injury and illness were measured with the Brief COPE instrument and the use of NSAIDs was investigated. Complete survey data were provided by 161 runners (47%). 42% reported NSAID use. A notable injury in the past year was reported by 43%, and 19% reported having had a time-loss illness episode. Runners who reported NSAID use in the past year reported significantly fewer time-loss injuries (p=0.003). Time loss due to illness only showed a negative correlation with using emotional support for coping (p=0.010) and a positive correlation with self-blame (p=0.039). Runners stating NSAID use reported fewer time-loss running injuries than non-NSAID users. Time loss due to illness showed different correlates with NSAID use and coping strategies than time loss due to injury, i.e. no association with drug use, less use of emotional support for coping and more use of self-blame.

  17. Delineation of Ehlers-Danlos syndrome phenotype due to the c.934C>T, p.(Arg312Cys) mutation in COL1A1: Report on a three-generation family without cardiovascular events, and literature review.

    Science.gov (United States)

    Colombi, Marina; Dordoni, Chiara; Venturini, Marina; Zanca, Arianna; Calzavara-Pinton, Piergiacomo; Ritelli, Marco

    2017-02-01

    Classical Ehlers-Danlos syndrome (cEDS) is a rare connective tissue disorder primarily characterized by hyperextensible skin, defective wound healing, abnormal scars, easy bruising, and generalized joint hypermobility; arterial dissections are rarely observed. Mutations in COL5A1 and COL5A2 encoding type V collagen account for more than 90% of the patients so far characterized. In addition, cEDS phenotype was reported in a small number of patients carrying the c.934C>T mutation in COL1A1 that results in an uncommon substitution of a non-glycine residue in one Gly-Xaa-Yaa repeat of the pro-α1(I)-chain p.(Arg312Cys), which leads to disturbed collagen fibrillogenesis due to delayed removal of the type I procollagen N-propeptide. This specific mutation has been associated with propensity to arterial rupture in early adulthood; indeed, in literature the individuals harboring this mutation are also referred to as "(classic) vascular-like" EDS patients. Herein, we describe a three-generation cEDS family with six adults carrying the p.(Arg312Cys) substitution, which show a variable and prevalent cutaneous involvement without any major vascular event. These data, together with those available in literature, suggest that vascular events are not a diagnostic handle to differentiate patients with the p.(Arg312Cys) COL1A1 mutation from those with COL5A1 and COL5A2 defects, and highlight that during the diagnostic process the presence of at least the p.(Arg312Cys) substitution in COL1A1 should be investigated in cEDS patients without type V collagen mutations. Nevertheless, for these patients, as well as for those affected with cEDS, a periodical vascular surveillance should be carried out together with cardiovascular risk factors monitoring. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  18. Assessing and modeling sediment mobility in estuarine and coastal settings due to extreme climate events from natural short-lived isotope distribution

    Science.gov (United States)

    Ghaleb, Bassam; Hillaire-Marcel, Claude; Ruiz Fernandez, Ana-Carolina; Sanchez Cabeza, Joan-Albert

    2016-04-01

    provide simple models governing these processes under relatively high sedimentation rates, i.e., when Ra-diffusion from the sediment towards the water column may be neglected. In sites characterized by extreme sedimentologival events, 228Th/232Th profiles depict departures from this model, thus bearing information on the timing and processes involved. Examples from the Saguenay Fjord (Canada) illustrate the case of fast-deposited layers due to floods, whereas examples from estuaries and coastal areas of Sinaloa show evidence for re-suspension and/or erosion events linked notably to storminess and/or land use changes. In the first case, the fast accumulation of flood layers has sealed most of the early 20th-century contamination, whereas in the second case, erosion and re-suspension events led to either some removal of sediments contaminated by heavy metals, or their secondary release into the environment.

  19. Events occurring during the previous lactation, the dry period, and peripartum as risk factors for early lactation mastitis in cows receiving 2 different intramammary dry cow therapies.

    Science.gov (United States)

    Pinedo, P J; Fleming, C; Risco, C A

    2012-12-01

    The objective of this study was to investigate the association between mastitis events occurring during the previous lactation, the dry period, and the peripartum period on the incidence of early lactation mastitis in cows receiving ceftiofur hydrochloride or penicillin dihydrostreptomycin as intramammary dry cow antibiotic therapy. Cows (n=402) from 2 large dairy farms in Central Florida were enrolled in the study at the time of dry-off processing and were randomly assigned to 1 of 2 dry cow therapies: ceftiofur hydrochloride or penicillin dihydrostreptomycin. Composite milk samples were collected at dry-off and after calving for bacteriological examination and somatic cell count. Peripartal health disorders were monitored during the first 30 d of lactation and included calving difficulty, metritis, ketosis, and left displaced abomasum. Milk production and individual somatic cell scores (SCS) were recorded monthly by the Dairy Herd Improvement Association. The main outcome variables were the risk of clinical mastitis during the first 30 and 60 d of lactation, and the risk of subclinical mastitis at the first 2 monthly Dairy Herd Improvement Association tests after calving (up to 70 d in milk). Additionally, the SCS and the presence of mastitis pathogens in milk at dry-off and at calving were analyzed. Explanatory variables consisted of events occurring during the previous lactation, at dry-off and during the dry period, at calving, and within the first 30 d after calving. Multiple events occurring during the previous lactation had a significant effect on the incidence of mastitis in the subsequent lactation. These events included low milk yield, intermediate lactation length, clinical mastitis, and lactation SCS average. Similarly, intramammary infections with environmental bacteria at dry-off increased the chances of clinical mastitis the first month after calving. Dry-off therapy had a significant effect on mastitis incidence; cows treated with ceftiofur

  20. Attendance at cultural events, reading books or periodicals, and making music or singing in a choir as determinants for survival: Swedish interview survey of living conditions.

    Science.gov (United States)

    Bygren, L. O.; Konlaan, B. B.; Johansson, S. E.

    1996-01-01

    OBJECTIVES: To investigate the possible influence of attendance at cultural events, reading books or periodicals, making music or singing in a choir as determinants for survival. DESIGN: A simple random sample was drawn of 15,198 individuals aged 16-74 years. Of these, 85% (12,982) were interviewed by trained non-medical interviewers between 1982 and 1983 about cultural activities. They were followed up with respect to survival until 31 December 1991. SETTING: Swedish interview survey of living conditions comprising a random sample of the adult Swedish population. SUBJECTS: 12,675 people interviewed between 1982 and 1983. MAIN OUTCOME MEASURES: Survival of subjects after controlling for eight confounding variables: age, sex, education level, income, long term disease, social network, smoking, and physical exercise. RESULTS: 6,301 men and 6,374 women were followed up; 533 men and 314 women died during this period. The control variables influenced survival in the expected directions except for social network for men; a significant negative effective was found when the analysis was made separately for men and women. We found an influence on mortality when the eight control variables were controlled for in people who rarely attended events compared with those attending most often, the relative risk being 1.57 (95% confidence interval 1.18 to 2.09). CONCLUSION: Attendance at cultural events may have a positive influence on survival. Long term follow up of large samples with confounders that are well controlled for and with the cultural stimulation more highly specified should be used to try to falsify the hypothesis before experiments start. PMID:8990990

  1. Animal evolution and atmospheric pO2: is there a link between gradual animal adaptation to terrain elevation due to Ural orogeny and survival of subsequent hypoxic periods?

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    Kurbel, Sven

    2014-10-22

    Considering evolution of terrestrial animals as something happening only on flat continental plains seems wrong. Many mountains have arisen and disappeared over the geologic time scale, so in all periods some areas of high altitude existed, with reduced oxygen pressure (pO2) and increased aridity. During orogeny, animal species of the raising terrain can slowly adapt to reduced oxygen levels.This review proposes that animal evolution was often driven by atmospheric oxygen availability. Transitions of insect ancestors and amphibians out of water are here interpreted as events forced by the lack of oxygen in shallow and warm water during Devonian. Hyperoxia during early Carboniferous allowed giant insects to be predators of lowlands, forcing small amphibians to move to higher terrains, unsuitable to large insects due to reduced pO2. In arid mountainous habitats, ascended animals evolved in early reptiles with more efficient lungs and improved circulation. Animals with alveolar lungs became the mammalian ancestors, while those with respiratory duct lungs developed in archosaurs. In this interpretation, limb precursors of wings and pneumatised bones might have been adaptations for moving on steep slopes.Ural mountains have risen to an estimated height of 3000 m between 318 and 251 Mya. The earliest archosaurs have been found on the European Ural side, estimated 275 Myr old. It is proposed that Ural orogeny slowly elevated several highland habitats within the modern Ural region to heights above 2500 m. Since this process took near 60 Myr, animals in these habitats fully to adapted to hypoxia.The protracted P-Tr hypoxic extinction event killed many aquatic and terrestrial animals. Devastated lowland areas were repopulated by mammaliaformes that came down from mountainous areas. Archosaurs were better adapted to very low pO2, so they were forced to descend to the sea level later when the lack of oxygen became severe. During the Triassic period, when the relative content

  2. Source mechanism of small long-period events at Mount St. Helens in July 2005 using template matching, phase-weighted stacking, and full-waveform inversion

    Science.gov (United States)

    Matoza, Robin S.; Chouet, Bernard A.; Dawson, Phillip B.; Shearer, Peter M.; Haney, Matthew M.; Waite, Gregory P.; Moran, Seth C.; Mikesell, T. Dylan

    2015-09-01

    Long-period (LP, 0.5-5 Hz) seismicity, observed at volcanoes worldwide, is a recognized signature of unrest and eruption. Cyclic LP "drumbeating" was the characteristic seismicity accompanying the sustained dome-building phase of the 2004-2008 eruption of Mount St. Helens (MSH), WA. However, together with the LP drumbeating was a near-continuous, randomly occurring series of tiny LP seismic events (LP "subevents"), which may hold important additional information on the mechanism of seismogenesis at restless volcanoes. We employ template matching, phase-weighted stacking, and full-waveform inversion to image the source mechanism of one multiplet of these LP subevents at MSH in July 2005. The signal-to-noise ratios of the individual events are too low to produce reliable waveform inversion results, but the events are repetitive and can be stacked. We apply network-based template matching to 8 days of continuous velocity waveform data from 29 June to 7 July 2005 using a master event to detect 822 network triggers. We stack waveforms for 359 high-quality triggers at each station and component, using a combination of linear and phase-weighted stacking to produce clean stacks for use in waveform inversion. The derived source mechanism points to the volumetric oscillation (˜10 m3) of a subhorizontal crack located at shallow depth (˜30 m) in an area to the south of Crater Glacier in the southern portion of the breached MSH crater. A possible excitation mechanism is the sudden condensation of metastable steam from a shallow pressurized hydrothermal system as it encounters cool meteoric water in the outer parts of the edifice, perhaps supplied from snow melt.

  3. Source mechanism of small long-period events at Mount St. Helens in July 2005 using template matching, phase-weighted stacking, and full-waveform inversion

    Science.gov (United States)

    Matoza, Robin S.; Chouet, Bernard A.; Dawson, Phillip B.; Shearer, Peter M.; Haney, Matthew M.; Waite, Gregory P.; Moran, Seth C.; Mikesell, T. Dylan

    2015-01-01

    Long-period (LP, 0.5-5 Hz) seismicity, observed at volcanoes worldwide, is a recognized signature of unrest and eruption. Cyclic LP “drumbeating” was the characteristic seismicity accompanying the sustained dome-building phase of the 2004–2008 eruption of Mount St. Helens (MSH), WA. However, together with the LP drumbeating was a near-continuous, randomly occurring series of tiny LP seismic events (LP “subevents”), which may hold important additional information on the mechanism of seismogenesis at restless volcanoes. We employ template matching, phase-weighted stacking, and full-waveform inversion to image the source mechanism of one multiplet of these LP subevents at MSH in July 2005. The signal-to-noise ratios of the individual events are too low to produce reliable waveform-inversion results, but the events are repetitive and can be stacked. We apply network-based template matching to 8 days of continuous velocity waveform data from 29 June to 7 July 2005 using a master event to detect 822 network triggers. We stack waveforms for 359 high-quality triggers at each station and component, using a combination of linear and phase-weighted stacking to produce clean stacks for use in waveform inversion. The derived source mechanism pointsto the volumetric oscillation (~10 m3) of a subhorizontal crack located at shallow depth (~30 m) in an area to the south of Crater Glacier in the southern portion of the breached MSH crater. A possible excitation mechanism is the sudden condensation of metastable steam from a shallow pressurized hydrothermal system as it encounters cool meteoric water in the outer parts of the edifice, perhaps supplied from snow melt.

  4. Muscle Weakness and Fibrosis Due to Cell Autonomous and Non-cell Autonomous Events in Collagen VI Deficient Congenital Muscular Dystrophy

    Directory of Open Access Journals (Sweden)

    Satoru Noguchi

    2017-02-01

    Full Text Available Congenital muscular dystrophies with collagen VI deficiency are inherited muscle disorders with a broad spectrum of clinical presentation and are caused by mutations in one of COL6A1–3 genes. Muscle pathology is characterized by fiber size variation and increased interstitial fibrosis and adipogenesis. In this study, we define critical events that contribute to muscle weakness and fibrosis in a mouse model with collagen VI deficiency. The Col6a1GT/GT mice develop non-progressive weakness from younger age, accompanied by stunted muscle growth due to reduced IGF-1 signaling activity. In addition, the Col6a1GT/GT mice have high numbers of interstitial skeletal muscle mesenchymal progenitor cells, which dramatically increase with repeated myofiber necrosis/regeneration. Our results suggest that impaired neonatal muscle growth and the activation of the mesenchymal cells in skeletal muscles contribute to the pathology of collagen VI deficient muscular dystrophy, and more importantly, provide the insights on the therapeutic strategies for collagen VI deficiency.

  5. Muscle Weakness and Fibrosis Due to Cell Autonomous and Non-cell Autonomous Events in Collagen VI Deficient Congenital Muscular Dystrophy.

    Science.gov (United States)

    Noguchi, Satoru; Ogawa, Megumu; Malicdan, May Christine; Nonaka, Ikuya; Nishino, Ichizo

    2017-02-01

    Congenital muscular dystrophies with collagen VI deficiency are inherited muscle disorders with a broad spectrum of clinical presentation and are caused by mutations in one of COL6A1-3 genes. Muscle pathology is characterized by fiber size variation and increased interstitial fibrosis and adipogenesis. In this study, we define critical events that contribute to muscle weakness and fibrosis in a mouse model with collagen VI deficiency. The Col6a1GT/GT mice develop non-progressive weakness from younger age, accompanied by stunted muscle growth due to reduced IGF-1 signaling activity. In addition, the Col6a1GT/GT mice have high numbers of interstitial skeletal muscle mesenchymal progenitor cells, which dramatically increase with repeated myofiber necrosis/regeneration. Our results suggest that impaired neonatal muscle growth and the activation of the mesenchymal cells in skeletal muscles contribute to the pathology of collagen VI deficient muscular dystrophy, and more importantly, provide the insights on the therapeutic strategies for collagen VI deficiency. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  6. Evolutionary History of the Live-Bearing Endemic Allotoca diazi Species Complex (Actinopterygii, Goodeinae: Evidence of Founder Effect Events in the Mexican Pre-Hispanic Period.

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    Diushi Keri Corona-Santiago

    Full Text Available The evolutionary history of Mexican ichthyofauna has been strongly linked to natural events, and the impact of pre-Hispanic cultures is little known. The live-bearing fish species Allotoca diazi, Allotoca meeki and Allotoca catarinae occur in areas of biological, cultural and economic importance in central Mexico: Pátzcuaro basin, Zirahuén basin, and the Cupatitzio River, respectively. The species are closely related genetically and morphologically, and hypotheses have attempted to explain their systematics and biogeography. Mitochondrial DNA and microsatellite markers were used to investigate the evolutionary history of the complex. The species complex shows minimal genetic differentiation. The separation of A. diazi and A. meeki was dated to 400-7000 years ago, explained by geological and climate events. A bottleneck and reduction of genetic diversity in Allotoca diazi was detected, attributed to recent climate fluctuations and anthropogenic activity. The isolation of A. catarinae occurred ~1900 years ago. No geological events are documented in the area during this period, but the date is contemporary with P'urhépecha culture settlements. This founder effect represents the first evidence of fish species translocation by a pre-Hispanic culture of Mexico. The response of the complex to climate fluctuation, geological changes and human activity in the past and the future according to the ecological niches predictions indicates areas of vulnerability and important information for conservation. The new genetic information showed that the Allotoca diazi complex consist of two genetic groups with an incomplete lineage sorting pattern: Pátzcuaro and Zirahuén lakes, and an introduced population in the Cupatitzio River.

  7. 2013 Immune Risk Standing Review Panel Research Plan Review for: The Risk of Crew Adverse Health Event Due to Altered Immune Response

    Science.gov (United States)

    Steinberg, Susan

    2014-01-01

    The 2013 Immune Risk Standing Review Panel (from here on referred to as the SRP) participated in a meeting with representatives from the Human Research Program (HRP) Human Health Countermeasures (HHC) Element and HRP management on February 3-4, 2014 in Houston, TX to review the updated Research Plan for the Risk of Crew Adverse Health Event Due to Altered Immune Response in the HRP Integrated Research Plan. The SRP is impressed with the work the immune discipline has done since the 2012 SRP review and agrees with the new wording of the Gaps, no longer questions, now statements. The SRP also likes the addition of adding targets for closing the Gaps, but it is not clear how they got to some of the interim stages (interval percentages). A major concern that the SRP has mentioned since the initial 2009 SRP meeting is that there is still not enough emphasis on the interdisciplinary aspect of the immune risk associated with other risks (i.e., nutrition, radiation, etc.). The SRP recommends that a "translational SRP" or advisory group be developed that is composed of members from all of the HRP SRPs. The SRP also thinks that the immune discipline should consider a more systems biology approach. Lastly, the SRP is concerned that the risks observed in research from low Earth orbit (LEO) missions may not accurately reflect all the risks of longer duration flight beyond LEO. Also, there does not seem to be a concern for immune responses that may occur when someone is in space longer than six months, for example, a Mars mission would take three years. The absence of disease in past and current flight scenarios does not mean the risk may not be there in future flight settings.

  8. Potential cost saving of Epoetin alfa in elective hip or knee surgery due to reduction in blood transfusions and their side effects: a discrete-event simulation model.

    Directory of Open Access Journals (Sweden)

    Jörg Tomeczkowski

    Full Text Available OBJECTIVES: Transfusion of allogeneic blood is still common in orthopedic surgery. This analysis evaluates from the perspective of a German hospital the potential cost savings of Epoetin alfa (EPO compared to predonated autologous blood transfusions or to a nobloodconservationstrategy (allogeneic blood transfusion strategyduring elective hip and knee replacement surgery. METHODS: Individual patients (N = 50,000 were simulated based on data from controlled trials, the German DRG institute (InEK and various publications and entered into a stochastic model (Monte-Carlo of three treatment arms: EPO, preoperative autologous donation and nobloodconservationstrategy. All three strategies lead to a different risk for an allogeneic blood transfusion. The model focused on the costs and events of the three different procedures. The costs were obtained from clinical trial databases, the German DRG system, patient records and medical publications: transfusion (allogeneic red blood cells: €320/unit and autologous red blood cells: €250/unit, pneumonia treatment (€5,000, and length of stay (€300/day. Probabilistic sensitivity analyses were performed to determine which factors had an influence on the model's clinical and cost outcomes. RESULTS: At acquisition costs of €200/40,000 IU EPO is cost saving compared to autologous blood donation, and cost-effective compared to a nobloodconservationstrategy. The results were most sensitive to the cost of EPO, blood units and hospital days. CONCLUSIONS: EPO might become an attractive blood conservation strategy for anemic patients at reasonable costs due to the reduction in allogeneic blood transfusions, in the modeled incidence of transfusion-associated pneumonia andthe prolongedlength of stay.

  9. Oceanic anoxic events of the Cretaceous period and their role in the formation of source rocks in the basins of continental margins

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    A.I. Konyukhov

    2017-09-01

    Full Text Available The Cretaceous period was marked not only by the dominance of warm climate, vast transgressions of the sea and widespread occurrence of carbonate deposits, but also by the formation of the richest petroleum formations, which are associated with the generation of a huge amount of hydrocarbons in the largest oil and gas basins of modern continental margins. Both early and late Cretaceous epochs were marked by several oceanic anoxic events (OAE of global and regional scale, accompanied by the accumulation of sediments enriched in organic matter, and by significant shifts in the ratios of stable isotopes C, O, and Sr. Various aspects of these events are considered in a huge number of articles published in recent years in major scientific publications. Unfortunately, their role in the formation of oil reservoirs has remained outside the scope of scientific analysis. Meanwhile Cretaceous OAE’s had led to the spreading of black shale and other sediments with high content of organic matter on the floor of Tethys ocean, central part of Atlantic and on the seamounts in the Pacific ocean. Among them only OAE 1a (Selli and OAE 2 (Bonarelli are known as more large anoxic events. The first occurred in the middle of Aptian time, the second near the Cenomanian-Turonian boundary (CTB. The analysis of the spreading of source rocks in the largest oil-and-gas bearing basins on the continental margins at that time – the Persian Gulf, Maracaibo, Middle and Upper Magdalena river, Putumayo and other basins – showed that episodes of OAE’s had not always found a reflection in the succession of major source rock’s formations. In the Persian Gulf a list of source rocks includes Hanifa, Garau, Gadvan, Kazhdumi, Ahmadi member and Gurpi formations of Cretaceous age. Thus it is certain that OAE’s were only separate parts of more complex history of accumulation of black shale and carbonate deposits with high content of total organic carbon on the continental margins

  10. Men's and women's experiences of violence and traumatic events in rural Cote d'Ivoire before, during and after a period of armed conflict.

    Science.gov (United States)

    Hossain, Mazeda; Zimmerman, Cathy; Kiss, Ligia; Kone, Drissa; Bakayoko-Topolska, Monika; Manan, David K A; Lehmann, Heidi; Watts, Charlotte

    2014-02-25

    We assessed men's and women's experiences of gender based violence and other traumatic events in Côte d'Ivoire, a West African conflict-affected setting, before, during and after a period of active armed conflict (2000-2007). Cross-sectional, household survey. 12 rural communities directly impacted by the Crisis in Côte d'Ivoire, spanning regions controlled by government forces, rebels and UN peacekeepers in 2008. 2678 men and women aged 15-49 years. Violence exposures measured since age 15. Questions included intimate partner physical and sexual violence; physical and sexual violence by others (including combatants) and exposure to traumatic events before, during and after the Crisis period (2000-2007). Physical and/or sexual violence since age 15 was reported by 57.1% women and 40.2% men (p=0.01); 29.9% women and 12.3% men reported exposure to any violence in the past year. Nearly 1 in 10 women (9.9%) and 5.9% men (p=0.03) were forced to have sex by a non-partner since age 15, and 14.8% women and 3.3% men (p=0.00) reported their first sexual experience was forced. Combatants were rarely reported as sexual violence perpetrators (0.3% women). After the Crisis, intimate partner physical violence was the most frequently reported form of violence and highest among women (20.9% women, 9.9% men, p=0.00). Fearing for their life was reported by men and women before, during and after the Crisis. Sexual violence in conflict remains a critical international policy concern. However, men and women experience different types of violence before, during and after conflict. In many conflict settings, other forms of violence, including intimate partner violence, may be more widespread than conflict-related sexual violence. Alongside service provision for rape survivors, our findings underscore the need for postconflict reconstruction efforts to invest in programmes to prevent and respond to intimate partner violence and trauma.

  11. Lateralized delay period activity marks the focus of spatial attention in working memory: evidence from somatosensory event-related brain potentials.

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    Katus, Tobias; Eimer, Martin

    2015-04-29

    The short-term retention of sensory information in working memory (WM) is known to be associated with a sustained enhancement of neural activity. What remains controversial is whether this neural trace indicates the sustained storage of information or the allocation of attention. To evaluate the storage and attention accounts, we examined sustained tactile contralateral delay activity (tCDA component) of the event-related potential. The tCDA manifests over somatosensory cortex contralateral to task-relevant tactile information during stimulus retention. Two tactile sample sets (S1, S2) were presented sequentially, separated by 1.5 s. Each set comprised two stimuli, one per hand. Human participants memorized the location of one task-relevant stimulus per sample set and judged whether one of these locations was stimulated again at memory test. The two relevant pulses were unpredictably located on the same hand (stay trials) or on different hands (shift trials). Initially, tCDA components emerged contralateral to the relevant S1 pulse. Sequential loading of WM enhanced the tCDA after S2 was presented on stay trials. On shift trials, the tCDA's polarity reversed after S2 presentation, resulting in delay activity that was now contralateral to the task-relevant S2 pulse. The disappearance of a lateralized neural trace for the relevant S1 pulse did not impair memory accuracy for this stimulus on shift trials. These results contradict the storage account and suggest that delay period activity indicates the sustained engagement of an attention-based rehearsal mechanism. In conclusion, somatosensory delay period activity marks the current focus of attention in tactile WM. Copyright © 2015 the authors 0270-6474/15/356689-07$15.00/0.

  12. Changes in groundwater reserves and radiocarbon and chloride content due to a wet period intercalated in an arid climate sequence in a large unconfined aquifer

    Science.gov (United States)

    Custodio, E.; Jódar, J.; Herrera, C.; Custodio-Ayala, J.; Medina, A.

    2018-01-01

    The concentration of atmospheric tracers in groundwater samples collected from springs and deep wells is, in most cases, the result of a mixture of waters with a wide range of residence times in the ground. Such is the case of an unconfined aquifer recharged over all its surface area. Concentrations greatly differ from the homogeneous residence time case. Data interpretation relies on knowledge of the groundwater flow pattern. To study relatively large systems, the conservative ion chloride and the decaying radiocarbon (14C) are considered. Radiocarbon (14C) activity in groundwater, after correction to discount the non-biogenic contribution, is often taken as an indication of water age, while chloride can be used to quantify recharge. In both cases, the observed tracer content in groundwater is an average value over a wide range which is related to water renewal time in the ground. This is shown considering an unconfined aquifer recharged all over its area under arid conditions, in which a period of greater recharge happened some millennia ago. The mathematical solution is given. As the solution cannot be made general, to show and discuss the changes in water reserve and in chloride and radiocarbon concentration (apparent ages), two scenarios are worked out, which are loosely related to current conditions in Northern Chile. It is shown that tracer concentration and the estimated water age are not directly related to the time since recharge took place. The existence of a previous wetter-than-present period has an important and lasting effect on current aquifer water reserves and chloride concentration, although the effect on radiocarbon activity is less pronounced. Chloride concentrations are smaller than in current recharge and apparent 14C ages do not coincide with the timing, duration and characteristics of the wet period, except in the case in which recharge before and after the wet period is negligible and dead aquifer reserves are non-significant. The use of

  13. CD70 Deficiency due to a Novel Mutation in a Patient with Severe Chronic EBV Infection Presenting As a Periodic Fever

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    Roberta Caorsi

    2018-01-01

    Full Text Available Primary immunodeficiencies with selective susceptibility to EBV infection are rare conditions associated with severe lymphoproliferation. We followed a patient, son of consanguineous parents, referred to our center for recurrent periodic episodes of fever associated with tonsillitis and adenitis started after an infectious mononucleosis and responsive to oral steroid. An initial diagnosis of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome was done. In the following months, recurrent respiratory infections and episodes of keratitis were also observed, together with a progressive reduction of immunoglobulin levels and an increase of CD20+ cells. Cell sorting and EBV PCR showed 25,000 copies for 100,000 leukocytes with predominant infection of B lymphocytes. Lymph node’s biopsy revealed reactive lymphadenopathy with paracortical involvement consistent with a chronic EBV infection. Molecular analysis of XIAP, SHA2D1A, ITK, and CD27 genes did not detect any pathogenic mutation. The patients underwent repeated courses of anti-CD20 therapy with only a partial control of the disease, followed by stem cell transplantation with a complete normalization of clinical and immunological features. Whole exome sequencing of the trio was performed. Among the variants identified, a novel loss of function homozygous c.163-2A>G mutation of the CD70 gene, affecting the exon 2 AG-acceptor splice site, fit the expected recessive model of inheritance. Indeed, deficiency of both CD27, and, more recently, of its ligand CD70, has been reported as a cause of EBV-driven lymphoproliferation and hypogammaglobulinemia. Cell surface analysis of patient-derived PHA-T cell blasts and EBV-transformed lymphoblastoid cell lines confirmed absence of CD70 expression. In conclusion, we describe a case of severe chronic EBV infection caused by a novel mutation of CD70 presenting with recurrent periodic fever.

  14. TCP J05074264+2447555 as a bright microlensing event due to a binary system with very low mass ratio component: hint for a new planetary system?

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    Nucita, A. A.; Licchelli, D.; De Paolis, F.; Ingrosso, G.; Strafella, F.

    2017-11-01

    The transient event labeled as TCP J05074264+2447555 (RA 05h07m42.64s, DEC +24°47'55.5" (J2000.0)) was first discovered by Kojima on UT 2017-10-25.688 in the Taurus region and suddenly recognized as something peculiar.

  15. [Dermatophytosis due to Trichophyton rubrum. Ten-year period (1996-2006) data collection in a Dermatology Department in Mexico City].

    Science.gov (United States)

    Hernández-Salazar, Amparo; Carbajal-Pruneda, Patricia; Fernández Martínez, Ramón; Arenas, Roberto

    2007-06-01

    Dermatophytosis is the most common mycosis in the world up to 80% caused by Trichophyton rubrum. The aim of the present study was to describe the clinical characteristics of the dermatophytosis caused by T. rubrum in a dermatological outpatient clinic during a ten years period, from 1996 to 2005. We collected the data from patients with a dermatophytosis from which we have isolated T. rubrum. A total of 776 patients with dermatophytosis caused by T. rubrum were found. A slight predominance of female patients (56.2%) was observed. The most commonly affected age group was those in the third to the fifth decade of life, and house working women (33.5%) were predominant. Onychomycosis was found in 63% of the cases, tinea pedis in 22.7%, tinea corporis in 5.2% and tinea cruris in 2.8%. In onychomycosis, the first toe nail was the most commonly affected (58.9%) and the dystrophic type was seen in 50.7% of them.

  16. Macrobenthic community changes due to dystrophic events and freshwater inflow: Changes in space and time in a Mediterranean lagoon (Gialova lagoon, SW Greece)

    Science.gov (United States)

    Chatzigeorgiou, Georgios; Reizopoulou, Sophia; Maidanou, Maria; Naletaki, Maria; Orneraki, Eleni; Apostolaki, Eugenia; Arvanitidis, Christos

    2011-07-01

    This paper considers the hypothesis that changes in community structure through the control of the larvae maintenance and of the biological traits of the species mostly contribute to the spatio-temporal community pattern. This is supported by the results of the study, the changes to the macrobenthic community pattern deriving from two sampling periods in Gialova lagoon (SW Greece), carried out on a seasonal basis for two yearly periods: 1994-95 and 1998-99. Cognetti's hypothesis that populations of the tolerant species occupying coastal marine habitats may belong to different species is another alternative hypothesis still to be tested. The importance of alternative management plans aiming at the amelioration of the hydrodynamic conditions of the lagoons and supported by continuous scientific monitoring is highlighted. Two canals bringing fresh water were opened at the beginning of the second sampling period, an intervention among others, suggested by the management plan proposed after the end of the first sampling period. The results show considerable variations in the values of the key environmental variables, for instance long periods with negative Redox potential values, decreased salinity and increased concentrations of the particulate organic matter and of the nutrients. The variables were correlated with the spatio-temporal community pattern, characterized during the second sampling period by: (i) greater dissimilarities among stations/seasons; (ii) disruption of the periodic trend observed on the seasonal scale; (iii) larger relative dissimilarities among the patterns stemming from the macrobenthos and the most abundant groups (polychaetes, molluscs, crustaceans); (iv) significant decrease in abundance or even the disappearance of several marine origin species, along with increased abundance in a few brackish-water species. All of the above changes in the community pattern are considered as early warning signals leading towards degradation, which has not

  17. Oral administration of Chinese herbal medicine during gestation period for preventing hemolytic disease of the newborn due to ABO incompatibility: A systematic review of randomized controlled trials.

    Science.gov (United States)

    Cao, Huijuan; Wu, Ruohan; Han, Mei; Caldwell, Patrina Ha Yuen; Liu, Jian-Ping

    2017-01-01

    About 85.3% of hemolytic disease of the newborn (HDN) is caused by maternal-fetal ABO blood group incompatibility. However, there is currently no recommended "best" therapy for ABO incompatibility during pregnancy. To systematically assess the safety and effectiveness of oral Chinese herbal medicine (CHM) for preventing HDN due to ABO incompatibility. The protocol of this review was registered on the PROSPERO website (No. CRD42016038637).Six databases were searched from inception to April 2016. Randomized controlled trials (RCTs) of CHM for maternal-fetal ABO incompatibility were included. The primary outcome was incidence of HDN. The Cochrane risk of bias tool was used to assess the methodological quality of included trials. Risk ratios (RR) and mean differences with 95% confidence interval were used as effect measures. Meta-analyses using Revman 5.3 software were conducted if there were sufficient trials without obvious clinical or statistical heterogeneity available. Totally 28 RCTs involving3413 women were included in the review. The majority of the trials had unclear or high risk of bias. Our study found that the rate of HDN and the incidence of neonatal jaundice might be 70% lower in the herbal medicine group compared with the usual care group (RR from 0.25 to 0.30).After treatment with herbal medicine, women were twice as likely to have antibody titers lower than 1:64 compared with women who received usual care(RR from 2.15 to 3.14) and the umbilical cord blood bilirubin level in the herbal medicine group was 4umol/L lower than in those receiving usual care. There was no difference in Apgar scores or birthweights between the two groups. This review found very low-quality evidence that CHM prevented HDN caused by maternal-fetal ABO incompatibility. No firm conclusions can be drawn regarding the effectiveness or safety of CHM for this condition.

  18. Change of Rainfall-runoff event hysteresis in suspended sediments due to surface decontamination in the area affected by the Fukushima Daiichi nuclear power plant accident

    Science.gov (United States)

    Onda, Y.; Yoshimura, K.; Taniguchi, K.; Kubo, T.; Smith, H.; Brake, W.; Kuramoto, T.; Sato, T.

    2016-12-01

    The Fukushima Daiichi Nuclear Power Plant (FDNPP) on March 2011 accident released massive amounts of radiocesium into the terrestrial environment such as Cs-137 and Cs-134. Where deposition density of Cs-137 exceeds loughly 500 kBq/m2, evacuation has been ordered, and the cropland and paddy field have become grassland in the summer of 2011.A large scale government funded research program has been started (Saito and Onda, 2015) to monitor the amount of radiocesium wash off from the catchments started June, 2011 (Yamashiki et al 2013) starting initial 6 sites in the Abukuma river watershed in the nested structure. Two stations were installed on the main river channel (Iwanuma; 5313 km2 and Fushiguro; 3645 km2), and the more highly-contaminated Kuchibuto sub-basin (Mizusakai; 7.5km2, Kuchibuto Upstream; 21.4 km2, Kuchibuto middle stream; 63 km2, Kuchibuto downstream; 135 km2) was selected for detailed monitoring. The sites are increased to 30 sites (Yoshimura et al., 2015) to cover the most of the area within 80 km from the FDNPP in 2013.Continuous measurements of flow and turbidity (for estimating suspended sediment concentration) were made at each monitoring station. Turbidity meters (Analyte turbidity meter, MacVan 3000-NTU) calibrated with bottom sediment of the Horai reservoir upstream the Abukuma river, and water level gauges (RuggedTROLL100) . During our monitoring of topsoil up to 5 cm and replaced with lower part of the soil taken nearby in the two upstream catchments (Kuchibuto upstream, Mizusakai ) mainly in 2014 to 2015.The change of rainfall-runoff event hysteresis in suspended sediments before and after the decontamination was significant. From 2011 to 2013. Most of the response of suspended sediment occurs before the rainfall peak. However, after 2014, the response occurs after the runoff events, and suspended sediment concentration has been increased especially in the stations where decontamination area ratio are high.

  19. Case report of a near medical event in stereotactic radiotherapy due to improper units of measure from a treatment planning system.

    Science.gov (United States)

    Gladstone, D J; Li, S; Jarvis, L A; Hartford, A C

    2011-07-01

    The authors hereby notify the Radiation Oncology community of a potentially lethal error due to improper implementation of linear units of measure in a treatment planning system. The authors report an incident in which a patient was nearly mistreated during a stereotactic radiotherapy procedure due to inappropriate reporting of stereotactic coordinates by the radiation therapy treatment planning system in units of centimeter rather than in millimeter. The authors suggest a method to detect such errors during treatment planning so they are caught and corrected prior to the patient positioning for treatment on the treatment machine. Using pretreatment imaging, the authors found that stereotactic coordinates are reported with improper linear units by a treatment planning system. The authors have implemented a redundant, independent method of stereotactic coordinate calculation. Implementation of a double check of stereotactic coordinates via redundant, independent calculation is simple and accurate. Use of this technique will avoid any future error in stereotactic treatment coordinates due to improper linear units, transcription, or other similar errors. The authors recommend an independent double check of stereotactic treatment coordinates during the treatment planning process in order to avoid potential mistreatment of patients.

  20. Disease burden evaluation of fall-related events in the elderly due to hypoglycemia and other diabetic complications: a clinical review

    Directory of Open Access Journals (Sweden)

    Malabu UH

    2014-08-01

    Full Text Available Usman H Malabu,1 Venkat N Vangaveti,1 Richard Lee Kennedy2 1School of Medicine and Dentistry, James Cook University, QLD, Australia; 2Department of Medicine, Deakin University, VIC, Australia Abstract: A hypoglycemia-induced fall is common in older persons with diabetes. The etiology of falls in this population is usually multifactorial, and includes microvascular and macrovascular complications and age-related comorbidities, with hypoglycemia being one of the major precipitating causes. In this review, we systematically searched the literature that was available up to March 31, 2014 from MEDLINE/PubMed, Embase, and Google Scholar using the following terms: hypoglycemia; insulin; diabetic complications; and falls in elderly. Hypoglycemia, defined as blood glucose <4.0 mmol/L (70 mg/dL requiring external assistance, occurs in one-third of elderly diabetics on glucose-lowering therapies. It represents a major barrier to the treatment of diabetes, particularly in the elderly population. Patients who experience hypoglycemia are at a high risk for adverse outcomes, including falls leading to bone fracture, seizures, cognitive dysfunction, and prolonged hospital stays. An increase in mortality has been observed in patients who experience any one of these events. Paradoxically, rational insulin therapy, dosed according to a patient's clinical status and the results of home blood glucose monitoring, so as to achieve and maintain recommended glycemic goals, can be an effective method for the prevention of hypoglycemia and falls in the elderly. Contingencies, such as clinician-directed hypoglycemia treatment protocols that guide the immediate treatment of hypoglycemia, help to limit both the duration and severity of the event. Older diabetic patients with or without underlying renal insufficiency or other severe illnesses represent groups that are at high risk for hypoglycemia-induced falls and, therefore, require lower insulin dosages. In this review

  1. Review the number of accidents in Tehran over a two-year period and prediction of the number of events based on a time-series model

    Science.gov (United States)

    Teymuri, Ghulam Heidar; Sadeghian, Marzieh; Kangavari, Mehdi; Asghari, Mehdi; Madrese, Elham; Abbasinia, Marzieh; Ahmadnezhad, Iman; Gholizadeh, Yavar

    2013-01-01

    Background: One of the significant dangers that threaten people’s lives is the increased risk of accidents. Annually, more than 1.3 million people die around the world as a result of accidents, and it has been estimated that approximately 300 deaths occur daily due to traffic accidents in the world with more than 50% of that number being people who were not even passengers in the cars. The aim of this study was to examine traffic accidents in Tehran and forecast the number of future accidents using a time-series model. Methods: The study was a cross-sectional study that was conducted in 2011. The sample population was all traffic accidents that caused death and physical injuries in Tehran in 2010 and 2011, as registered in the Tehran Emergency ward. The present study used Minitab 15 software to provide a description of accidents in Tehran for the specified time period as well as those that occurred during April 2012. Results: The results indicated that the average number of daily traffic accidents in Tehran in 2010 was 187 with a standard deviation of 83.6. In 2011, there was an average of 180 daily traffic accidents with a standard deviation of 39.5. One-way analysis of variance indicated that the average number of accidents in the city was different for different months of the year (P < 0.05). Most of the accidents occurred in March, July, August, and September. Thus, more accidents occurred in the summer than in the other seasons. The number of accidents was predicted based on an auto-regressive, moving average (ARMA) for April 2012. The number of accidents displayed a seasonal trend. The prediction of the number of accidents in the city during April of 2012 indicated that a total of 4,459 accidents would occur with mean of 149 accidents per day during these three months. Conclusion: The number of accidents in Tehran displayed a seasonal trend, and the number of accidents was different for different seasons of the year. PMID:26120405

  2. Projecting policy-relevant metrics for high summertime ozone pollution events over the eastern United States due to climate and emission changes during the 21st century

    Science.gov (United States)

    Rieder, Harald E.; Fiore, Arlene M.; Horowitz, Larry W.; Naik, Vaishali

    2015-01-01

    Over the eastern United States (EUS), nitrogen oxides (NOx) emission controls have led to improved air quality over the past two decades, but concerns have been raised that climate warming may offset some of these gains. Here we analyze the effect of changing emissions and climate, in isolation and combination, on EUS summertime surface ozone (O3) over the recent past and the 21st century in an ensemble of simulations performed with the Geophysical Fluid Dynamics Laboratory CM3 chemistry-climate model. The simulated summertime EUS O3 is biased high but captures the structure of observed changes in regional O3 distributions following NOx emission reductions. We introduce a statistical bias correction, which allows derivation of policy-relevant statistics by assuming a stationary mean state bias in the model, but accurate simulation of changes at each quantile of the distribution. We contrast two different 21st century scenarios: (i) representative concentration pathway (RCP) 4.5 and (ii) simulations with well-mixed greenhouse gases (WMGG) following RCP4.5 but with emissions of air pollutants and precursors held fixed at 2005 levels (RCP4.5_WMGG). We find under RCP4.5 no exceedance of maximum daily 8 hour average ozone above 75 ppb by mid-21st century, reflecting the U.S. NOx emissions reductions projected in RCP4.5, while more than half of the EUS exceeds this level by the end of the 21st century under RCP4.5_WMGG. Further, we find a simple relationship between the changes in estimated 1 year return levels and regional NOx emission changes, implying that our results can be generalized to estimate changes in the frequency of EUS pollution events under different regional NOx emission scenarios.

  3. Age-period-cohort effects in the incidence of hip fractures: political and economic events are coincident with changes in risk.

    Science.gov (United States)

    Alves, S Maria; Castiglione, D; Oliveira, C Maria; de Sousa, B; Pina, M Fátima

    2014-02-01

    An age-period cohort model was fitted to analyse time effects on hip fracture incidence rates by sex (Portugal, 2000-2008). Rates increased exponentially with age (age effect). Incidence rates decreased after 2004 for women and were random for men (period effect). New but comprehensive fluctuations in risk were coincident with major political/economic changes (cohort effect). Healthcare improvements have allowed prevention but have also increased life expectancy, resulting in more people being at risk. Our aim was to analyse the separate effects of age, period and cohort on incidence rates by sex in Portugal, 2000-2008. From the National Hospital Discharge Register, we selected admissions (aged ≥ 49 years) with hip fractures (ICD9-CM, codes 820.x) caused by low/moderate trauma (falls from standing height or less), readmissions and bone cancer cases. We calculated person-years at risk using population data from Statistics Portugal. To identify period and cohort effects for all ages, we used an age-period-cohort model (1-year intervals) followed by generalised additive models with a negative binomial distribution of the observed incidence rates of hip fractures. There were 77,083 hospital admissions (77.4 % women). Incidence rates increased exponentially with age for both sexes (age effect). Incidence rates fell after 2004 for women and were random for men (period effect). There was a general cohort effect similar in both sexes; risk of hip fracture altered from an increasing trend for those born before 1930 to a decreasing trend following that year. Risk alterations (not statistically significant) coincident with major political and economic change in the history of Portugal were observed around birth cohorts 1920 (stable-increasing), 1940 (decreasing-increasing) and 1950 (increasing-decreasing only among women). Hip fracture risk was higher for those born during major economically/politically unstable periods. Although bone quality reflects lifetime exposure

  4. The language used in describing autobiographical memories prompted by life period visually presented verbal cues, event-specific visually presented verbal cues and short musical clips of popular music.

    Science.gov (United States)

    Zator, Krysten; Katz, Albert N

    2017-07-01

    Here, we examined linguistic differences in the reports of memories produced by three cueing methods. Two groups of young adults were cued visually either by words representing events or popular cultural phenomena that took place when they were 5, 10, or 16 years of age, or by words referencing a general lifetime period word cue directing them to that period in their life. A third group heard 30-second long musical clips of songs popular during the same three time periods. In each condition, participants typed a specific event memory evoked by the cue and these typed memories were subjected to analysis by the Linguistic Inquiry and Word Count (LIWC) program. Differences in the reports produced indicated that listening to music evoked memories embodied in motor-perceptual systems more so than memories evoked by our word-cueing conditions. Additionally, relative to music cues, lifetime period word cues produced memories with reliably more uses of personal pronouns, past tense terms, and negative emotions. The findings provide evidence for the embodiment of autobiographical memories, and how those differ when the cues emphasise different aspects of the encoded events.

  5. SENTINEL EVENTS

    Directory of Open Access Journals (Sweden)

    Andrej Robida

    2004-09-01

    Full Text Available Background. The Objective of the article is a two year statistics on sentinel events in hospitals. Results of a survey on sentinel events and the attitude of hospital leaders and staff are also included. Some recommendations regarding patient safety and the handling of sentinel events are given.Methods. In March 2002 the Ministry of Health introduce a voluntary reporting system on sentinel events in Slovenian hospitals. Sentinel events were analyzed according to the place the event, its content, and root causes. To show results of the first year, a conference for hospital directors and medical directors was organized. A survey was conducted among the participants with the purpose of gathering information about their view on sentinel events. One hundred questionnaires were distributed.Results. Sentinel events. There were 14 reports of sentinel events in the first year and 7 in the second. In 4 cases reports were received only after written reminders were sent to the responsible persons, in one case no reports were obtained. There were 14 deaths, 5 of these were in-hospital suicides, 6 were due to an adverse event, 3 were unexplained. Events not leading to death were a suicide attempt, a wrong side surgery, a paraplegia after spinal anaesthesia, a fall with a femoral neck fracture, a damage of the spleen in the event of pleural space drainage, inadvertent embolization with absolute alcohol into a femoral artery and a physical attack on a physician by a patient. Analysis of root causes of sentinel events showed that in most cases processes were inadequate.Survey. One quarter of those surveyed did not know about the sentinel events reporting system. 16% were having actual problems when reporting events and 47% beleived that there was an attempt to blame individuals. Obstacles in reporting events openly were fear of consequences, moral shame, fear of public disclosure of names of participants in the event and exposure in mass media. The majority of

  6. Economic and history timeline of the consecutive events of the progressive development of the national economic education at western Ukrainian territory in a period of the early XIX – XX centuries: educational institutionalization of economic systems

    Directory of Open Access Journals (Sweden)

    Holubka Mykhailo

    2016-06-01

    Full Text Available In scientific work, the economic and historical chronology of events of the consistent progressive development of national economic education in Western Ukraine in the early XIX and XX centuries is reviewed. The research is structured within the economic and historical chronology, and attention is paid to Western Ukrainian intelligentsia in terms of their influence on the further successful development of economic education in the western region in a designated period.

  7. Projected changes of rainfall event characteristics for the Czech Republic

    Directory of Open Access Journals (Sweden)

    Svoboda Vojtěch

    2016-12-01

    Full Text Available Projected changes of warm season (May–September rainfall events in an ensemble of 30 regional climate model (RCM simulations are assessed for the Czech Republic. Individual rainfall events are identified using the concept of minimum inter-event time and only heavy events are considered. The changes of rainfall event characteristics are evaluated between the control (1981–2000 and two scenario (2020–2049 and 2070–2099 periods. Despite a consistent decrease in the number of heavy rainfall events, there is a large uncertainty in projected changes in seasonal precipitation total due to heavy events. Most considered characteristics (rainfall event depth, mean rainfall rate, maximum 60-min rainfall intensity and indicators of rainfall event erosivity are projected to increase and larger increases appear for more extreme values. Only rainfall event duration slightly decreases in the more distant scenario period according to the RCM simulations. As a consequence, the number of less extreme heavy rainfall events as well as the number of long events decreases in majority of the RCM simulations. Changes in most event characteristics (and especially in characteristics related to the rainfall intensity depend on changes in radiative forcing and temperature for the future periods. Only changes in the number of events and seasonal total due to heavy events depend significantly on altitude.

  8. Environmental Conditions in a Carpathian Deep Sea Basin During the Period Preceding Oceanic Anoxic Event 2 - A Case Study from the Skole Nappe

    Directory of Open Access Journals (Sweden)

    Bąk Krzysztof

    2015-01-01

    Full Text Available Hemipelagic green clayey shales and thin muddy turbidites accumulated in a deep sea environment below the CCD in the Skole Basin, a part of the Outer Carpathian realm, during the Middle Cenomanian. The hemipelagites contain numerous radiolarians, associated with deep-water agglutinated foraminifera. These sediments accumulated under mesotrophic conditions with limited oxygen concentration. Short-term periodic anoxia also occurred during that time. Muddy turbidity currents caused deposition of siliciclastic and biogenic material, including calcareous foramini-fers and numerous sponge spicules. The preservation and diversity of the spicules suggests that they originate from disarticulation of moderately diversified sponge assemblages, which lived predominantly in the neritic-bathyal zone. Analyses of radiolarian ecological groups and pellets reflect the water column properties during the sedimentation of green shales. At that time, surface and also intermediate waters were oxygenated enough and sufficiently rich in nutri-ents to enable plankton production. Numerous, uncompacted pellets with nearly pristine radiolarian skeletons inside show that pelletization was the main factor of radiolarian flux into the deep basin floor. Partly dissolved skeletons indicate that waters in the Skole Basin were undersaturated in relation to silica content. Oxygen content might have been depleted in the deeper part of the water column causing periodic anoxic conditions which prevent rapid bacterial degra-dation of the pellets during their fall to the sea floor.

  9. Early life disease programming during the preconception and prenatal period: making the link between stressful life events and type-1 diabetes.

    Directory of Open Access Journals (Sweden)

    Jasveer Virk

    Full Text Available BACKGROUND: To assess the risk of developing Type-1 diabetes among children who were exposed to maternal bereavement during the prenatal or 1-year preconception period. METHODS: We identified N = 1,548,746 singleton births born in Denmark between January 1(st 1979 through December 31(st 2004, and their next of kin. Altogether, 39,857 children were exposed to bereavement during their prenatal life. The main outcome of interest was hospitalization for type-1 diabetes (ICD 8: 249; ICD 10: E10. RESULTS: We found the strongest association for type-1 diabetes among children exposed to traumatic father or sibling deaths (aIRR: 2.03, 1.22-3.38; the association was mainly seen for girls (aIRR: 2.91, 1.61-5.26. CONCLUSIONS: We found evidence to suggest that female fetuses exposed to severe prenatal stress are at increased risk for developing type-1 diabetes.

  10. Comparative study of adverse events after yellow fever vaccination between elderly and non-elderly travellers: questionnaire survey in Japan over a 1-year period.

    Science.gov (United States)

    Tanizaki, Ryutaro; Ujiie, Mugen; Hori, Narumi; Kanagawa, Shuzo; Kutsuna, Satoshi; Takeshita, Nozomi; Hayakawa, Kayoko; Kato, Yasuyuki; Ohmagari, Norio

    2016-03-01

    A live attenuated yellow fever (YF) vaccination is required of all travellers visiting countries where YF virus is endemic. Although the risk of serious adverse events (AEs) after YF vaccination is known to be greater in elderly people than in younger people, information about other AEs among elderly travellers is lacking. A prospective observational questionnaire study was conducted to investigate the occurrence of AEs after YF vaccination in travellers who attended a designated YF vaccination centre in Tokyo, Japan, from 1 November 2011 to 31 October 2012. A questionnaire enquiring about any AEs experienced in the 2 weeks following YF vaccination was distributed to all vaccinees enrolled in this study, and responses were collected subsequently by mail or phone. For child vaccinees, their parents were allowed to respond in their stead. Of the 1298 vaccinees who received the YF vaccine, 1044 (80.4%) were enrolled in the present study and 666 (63.8%) responded to the questionnaire. Of these 666 respondents, 370 (55.6%) reported AEs, of which 258 (38.7%) were systemic and 230 (34.5%) were local. No severe AEs associated with YF vaccination were reported. Elderly vaccinees (aged ≥60 years) reported fewer total AEs than those aged yellow vaccination reported among elderly vaccinees than among non-elderly vaccinees. These results could provide supplementary information for judging the adaptation of vaccination in elderly travellers. © International Society of Travel Medicine, 2016. All rights reserved. Published by Oxford University Press. For permissions, please e-mail: journals.permissions@oup.com.

  11. A due

    DEFF Research Database (Denmark)

    to acknowledge the excellence of these two scholars by a double Festschrift, "A due". Both have been working at the Music Department of the University of Copenhagen and have collaborated with The Royal Library on various projects. This publication contains contributions from 44 colleagues, who thus - in topics...

  12. Comparative evaluation of copeptin and NT-proBNP in patients with severe acute decompensated heart failure, and prediction of adverse events in a 90-day follow-up period: A prospective clinical observation trial.

    Science.gov (United States)

    Jia, Jun; Chang, Guang-Lei; Qin, Shu; Chen, Jia; He, Wen-Yan; Lu, Kai; Li, Yong; Zhang, Dong-Ying

    2017-04-01

    The present study compared the prognostic value of a marker, the C-terminal section of the arginine vasopressin prohormone (copeptin), with N-terminal B-type natriuretic peptide (NT-proBNP) in patients with severe acute decompensated heart failure. A prospective, observational cohort study was conducted in a tertiary care hospital and enrolled 129 patients with severe acute decompensated heart failure. Clinicians were blinded to investigational markers except NT-proBNP, and the study participants were followed up for 90 days. The end-point was a composite of cardiovascular death or re-hospitalization due to decompensated heart failure. Of the 129 patients enrolled, 47 reached the end-point and 82 were in a stable condition during follow-up. Receiver operating characteristic curve analysis revealed that the areas under curve for the prediction of adverse events within 90 days were similar for copeptin [0.602±0.052; 95% confidence interval (CI), 0.499-0.705], NT-proBNP (0.659±0.048; 95% CI, 0.565-0.753) and their combination (0.670±0.050; 95% CI, 0.573-0.767). Kaplan-Meier survival analysis showed that the predictive value of NT-proBNP regarding the probability of survival was superior compared with that of copeptin (log-rank test for trend, P=0.001 vs. 0.040). Furthermore, multivariate Cox proportional-hazards regression analysis revealed that increased NT-proBNP and copeptin plasma concentrations were significant independent predictors of adverse events. The present study provided evidence that copeptin has similar predictive properties compared with NT-proBNP regarding adverse events within 90-days in patients with severe acute decompensated heart failure, but that copeptin may not provide superior 90-day prediction compared to NT-proBNP.

  13. Growth hormone deficiency due to sports-related head trauma is associated with impaired cognitive performance in amateur boxers and kickboxers as revealed by P300 auditory event-related potentials.

    Science.gov (United States)

    Tanriverdi, Fatih; Suer, Cem; Yapislar, Hande; Kocyigit, Ismail; Selcuklu, Ahmet; Unluhizarci, Kursad; Casanueva, Felipe F; Kelestimur, Fahrettin

    2013-05-01

    It has been recently reported that boxing and kickboxing may cause pituitary dysfunction, GH deficiency in particular. The strong link between poor cognitive performance and GH deficiency due to causes other than head trauma and the improvement of cognitive function after GH replacement therapy have been previously shown. P300 auditory event-related potential (ERP) measure is widely used to evaluate cognitive performance. In this study, we investigated the relation between the GH-IGF-I axis and cognitive performance in boxers and kickboxers. Forty-one actively competing or retired male boxers (n: 27) and kickboxers (n: 14) with a mean age of 29·04 ± 9·30 year and 14 age- and education-matched healthy male controls were included in the study. For neuropsychological tests, the mini-mental state examination (MMSE) and Quality of Life Assessment of GH Deficiency in Adults (QoL-AGHDA) questionnaires were administered. Moreover, cognitive performance was evaluated according to P300 ERPs. Nine of 41 (21·9%) athletes had GH deficiency. P300 amplitudes were lower at all electrode sites in the GH-deficient group than in controls, and the differences were statistically significant at Fz and Oz electrode sites (P P300 amplitudes were lower at all electrode sites in the GH-deficient group; these differences were statistically significant at Fz, Pz and Cz electrode sites (P P300 latencies, and there were significant positive correlations between IGF-I levels vs P300 amplitudes (P relation between the P300 ERPs and the GH-IGF-I axis in boxers and kickboxers. © 2012 Blackwell Publishing Ltd.

  14. Burstiness parameter for finite event sequences

    CERN Document Server

    Kim, Eun-Kyeong

    2016-01-01

    Characterizing inhomogeneous temporal patterns in natural and social phenomena is important to understand underlying mechanisms behind such complex systems, hence even to predict and control them. Temporal inhomogeneities in event sequences have been described in terms of bursts that are rapidly occurring events in short time periods alternating with long inactive periods. The bursts can be quantified by a simple measure, called burstiness parameter, which was introduced by Goh and Barab\\'asi [EPL \\textbf{81}, 48002 (2008)]. The burstiness parameter has been widely used due to its simplicity, which however turns out to be strongly biased when the number of events in the time series is not large enough. As the finite size effects on burstiness parameter have been largely ignored, we analytically investigate the finite size effects of the burstiness parameter. Then we suggest an alternative definition of burstiness parameter that is unbiased and yet simple. Using our alternative burstiness parameter, one can di...

  15. Historiske perioder

    DEFF Research Database (Denmark)

    2017-01-01

    For at forstå fortiden og fortællingerne om den, må vi skabe en form for orden og systematik. Her spiller inddelingen af fortiden i historiske perioder en afgørende rolle – og historiske perioder er da også et kompetencemål efter 6. klasse. Videoen diskuterer forskellige principper...... for periodisering. Kronologi og sammenhænge hænger naturligt sammen med historiske perioder. Videoen handler også om forståelser og brug af synkrone og diakrone sammenhænge i faget....

  16. Event studies in Turkey

    Directory of Open Access Journals (Sweden)

    Ulkem Basdas

    2014-09-01

    Full Text Available The primary goal of this paper is to review the event studies conducted for Turkey to in order to identify the common components in their designs. This paper contributes to the existing literature by reviewing all event studies for Turkey for the first time, but more importantly; this review leads to the upcoming event studies on Turkey by highlighting main components of a proper design. Based on the review of 75 studies, it is observed that event studies generally choose BIST-100 (formerly, ISE-100 market index and market adjusted returns with the parametric tests. In general, the studies prefer to rely on one type of model to calculate abnormal returns without discussing the selection of the underlying model. Especially for the event studies focusing on the impact of political events or macroeconomic announcements in Turkey, there is a risk of clustering due to the application of same event date for all observations.

  17. Event based surveillance of Middle East Respiratory Syndrome Coronavirus (MERS- CoV) in Bangladesh among pilgrims and travelers from the Middle East: An update for the period 2013–2016

    Science.gov (United States)

    Parveen, Rezina; Sultana, Sharmin; Alam, Ahmed Nawsher; Akram, Arifa; Rahman, Mahmudur

    2018-01-01

    Introduction Every year around 150,000 pilgrims from Bangladesh perform Umrah and Hajj. Emergence and continuous reporting of MERS-CoV infection in Saudi Arabia emphasize the need for surveillance of MERS-CoV in returning pilgrims or travelers from the Middle East and capacity building of health care providers for disease containment. The Institute of Epidemiology, Disease Control & Research (IEDCR) under the Bangladesh Ministry of Health and Family welfare (MoHFW), is responsible for MERS-CoV screening of pilgrims/ travelers returning from the Middle East with respiratory illness as part of its outbreak investigation and surveillance activities. Methods Bangladeshi travelers/pilgrims who returned from the Middle East and presented with fever and respiratory symptoms were studied over the period from October 2013 to June 2016. Patients with respiratory symptoms that fulfilled the WHO MERS-CoV case algorithm were tested for MERS-CoV and other respiratory tract viruses. Beside surveillance, case recognition training was conducted at multiple levels of health care facilities across the country in support of early detection and containment of the disease. Results Eighty one suspected cases tested by real time PCR resulted in zero detection of MERS-CoV infection. Viral etiology detected in 29.6% of the cases was predominantly influenza A (H1N1 and H3N2), and influenza B infection (22%). Peak testing occurred mostly following the annual Hajj season. Conclusions Respiratory tract infections in travelers/pilgrims returning to Bangladesh from the Middle East are mainly due to influenza A and influenza B. Though MERS-CoV was not detected in the 81 patients tested, continuous screening and surveillance are essential for early detection of MERS-CoV infection and other respiratory pathogens to prevent transmissions in hospital settings and within communities. Awareness building among healthcare providers will help identify suspected cases. PMID:29337997

  18. Event based surveillance of Middle East Respiratory Syndrome Coronavirus (MERS- CoV) in Bangladesh among pilgrims and travelers from the Middle East: An update for the period 2013-2016.

    Science.gov (United States)

    Muraduzzaman, A K M; Khan, Manjur Hossain; Parveen, Rezina; Sultana, Sharmin; Alam, Ahmed Nawsher; Akram, Arifa; Rahman, Mahmudur; Shirin, Tahmina

    2018-01-01

    Every year around 150,000 pilgrims from Bangladesh perform Umrah and Hajj. Emergence and continuous reporting of MERS-CoV infection in Saudi Arabia emphasize the need for surveillance of MERS-CoV in returning pilgrims or travelers from the Middle East and capacity building of health care providers for disease containment. The Institute of Epidemiology, Disease Control & Research (IEDCR) under the Bangladesh Ministry of Health and Family welfare (MoHFW), is responsible for MERS-CoV screening of pilgrims/ travelers returning from the Middle East with respiratory illness as part of its outbreak investigation and surveillance activities. Bangladeshi travelers/pilgrims who returned from the Middle East and presented with fever and respiratory symptoms were studied over the period from October 2013 to June 2016. Patients with respiratory symptoms that fulfilled the WHO MERS-CoV case algorithm were tested for MERS-CoV and other respiratory tract viruses. Beside surveillance, case recognition training was conducted at multiple levels of health care facilities across the country in support of early detection and containment of the disease. Eighty one suspected cases tested by real time PCR resulted in zero detection of MERS-CoV infection. Viral etiology detected in 29.6% of the cases was predominantly influenza A (H1N1 and H3N2), and influenza B infection (22%). Peak testing occurred mostly following the annual Hajj season. Respiratory tract infections in travelers/pilgrims returning to Bangladesh from the Middle East are mainly due to influenza A and influenza B. Though MERS-CoV was not detected in the 81 patients tested, continuous screening and surveillance are essential for early detection of MERS-CoV infection and other respiratory pathogens to prevent transmissions in hospital settings and within communities. Awareness building among healthcare providers will help identify suspected cases.

  19. Artificial intelligence based event detection in wireless sensor networks

    OpenAIRE

    Bahrepour, M.

    2013-01-01

    Wireless sensor networks (WSNs) are composed of large number of small, inexpensive devices, called sensor nodes, which are equipped with sensing, processing, and communication capabilities. While traditional applications of wireless sensor networks focused on periodic monitoring, the focus of more recent applications is on fast and reliable identification of out-of-ordinary situations and events. This new functionality of wireless sensor networks is known as event detection. Due to the fact t...

  20. The drone as an additional risk factor due to conditions not provided for in radiological safety at major events; O drone como fator adicional de risco decorrente de condicoes nao previstas na seguranca radiologica em grandes eventos

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Gilberto de Jesus

    2015-07-01

    Major international events are potential targets of terrorist actions, seeking instant publicity that events of this magnitude provide, with the intention of causing terror and disseminate its power to a large number of people worldwide. In this context, the critical analysis of additional risk factor linked to procedures and protocols adopted on radiation safety is important. The possibility of unforeseen situations of risk, especially those resulting from the current global technological development, is a fact. Radioactive material can be used in this type of terrorism in a wide range of devices and illicit trafficking of this material is a reality that worries the International Atomic Energy Agency. In the current technological development scenario of the world, the potential occurrence of terrorist acts using drones combined with radioactive material dispersal devices, is real. The recent history of drones incidents presents cases where, despite not having been necessarily terrorist motivation, their circumstances and characteristics favor the occurrence of malicious acts. This paper proposes to alert the need of updating the current security protocols, considering the potential association of this technology with radioactive dispersal devices. (author)

  1. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    are dynamic and we present a modeling approach that can be used to model such dynamics. We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can......The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... be characterized by their occurrence times and the participating books and borrowers. When we characterize events as information objects we focus on concepts like information structures. When viewed as change agents events are phenomena that trigger change. For example, when borrow event occurs books are moved...

  2. PERIODIC BEHAVIORS

    NARCIS (Netherlands)

    Napp, Diego; Put, Marius van der; Shankar, Shiva

    2010-01-01

    This paper studies behaviors that are defined on a torus, or equivalently, behaviors defined in spaces of periodic functions, and establishes their basic properties analogous to classical results of Malgrange, Palamodov, Oberst et al. for behaviors on R(n). These properties-in particular the

  3. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... are dynamic and we present a modeling approach that can be used to model such dynamics.We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can...

  4. Extreme Energy Events Monitoring report

    CERN Document Server

    Baimukhamedova, Nigina

    2015-01-01

    Following paper reflects the progress I made on Summer Student Program within Extreme Energy Events Monitor project I was working on. During 8 week period I managed to build a simple detector system that is capable of triggering events similar to explosions (sudden change in sound levels) and measuring approximate location of the event. Source codes are available upon request and settings described further.

  5. Linkage of health and aged care service events: comparing linkage and event selection methods

    Directory of Open Access Journals (Sweden)

    Rosman Diana

    2008-07-01

    Full Text Available Abstract Background Data linkage is a technique that has long been used to connect information across several disparate data sources – most commonly for medical and population health research. Often the purpose is to connect data for individuals over extended time periods or across different service settings, and so person-based linkage using detailed personal information is preferred. Linkage which aims to link connected events, on the other hand, requires information about the time and place of the event as well as the person or persons involved in that event in order to make high quality linkages. This paper describes the detailed process of event linkage and compares directly an event-based linkage method for identifying transition events between two care sectors in Australia with a well-established high quality longitudinal person-based linkage which facilitates identification of event data for individuals. Methods Direct comparisons are made between transition events identified using an event-based linkage and an existing person-based linkage for people moving from hospital into aged care in Western Australia. Several aspects of event-based linkage are examined: refinement of the strategy to reduce false positives, causes of false positives and false negatives, quality of the linked event dataset, and utility of the linked event dataset for transition analysis. Results Over 97% of the event-based links were among those selected using the person-based linkage and over 90% of the latter were identified by the event-based method, with the remainder missed mostly due to differences in reported event date or residential region. Consequently the two linked datasets were sufficiently similar to give very similar results for analyses, but the actual volume of movement from hospital to RAC was underestimated by about 10% by the event-based method. Conclusion This project has allowed a 'preferred event' event-based linkage strategy to be selected

  6. Forecast of icing events at a wind farm in Sweden

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik

    2014-01-01

    This paper introduces a method for identifying icing events using a physical icing model, driven by atmospheric data from the Weather Research and Forecasting (WRF) model, and applies it to a wind park in Sweden. Observed wind park icing events were identified by deviation from an idealized power...... was found to be very important for forecasting the correct icing period. One concern with the iceBlade approach was the relatively high false alarm rates at the end of icing events due to the ice not being removed rapidly enough. © 2014 American Meteorological Society....

  7. Events and Effects

    DEFF Research Database (Denmark)

    Rytter, Mikkel

    2010-01-01

    Analyzing the period of ‘intensive transnationalism’ among Pakistani migrants in Denmark precipitated by the 2005 earthquake in Kashmir, this article explores the relationship between events and effects on a global scale. One significant initiative after the disaster was the founding of an ad hoc...

  8. Distinguishing high surf from volcanic long-period earthquakes

    Science.gov (United States)

    Lyons, John; Haney, Matt; Fee, David; Paskievitch, John F.

    2014-01-01

    Repeating long-period (LP) earthquakes are observed at active volcanoes worldwide and are typically attributed to unsteady pressure fluctuations associated with fluid migration through the volcanic plumbing system. Nonvolcanic sources of LP signals include ice movement and glacial outburst floods, and the waveform characteristics and frequency content of these events often make them difficult to distinguish from volcanic LP events. We analyze seismic and infrasound data from an LP swarm recorded at Pagan volcano on 12–14 October 2013 and compare the results to ocean wave data from a nearby buoy. We demonstrate that although the events show strong similarity to volcanic LP signals, the events are not volcanic but due to intense surf generated by a passing typhoon. Seismo-acoustic methods allow for rapid distinction of volcanic LP signals from those generated by large surf and other sources, a critical task for volcano monitoring.

  9. 78 FR 54571 - Special Local Regulation for Marine Event Hampton Bay Days Festival, Hampton River; Hampton, VA

    Science.gov (United States)

    2013-09-05

    ... cover the time frame specified for the event was not discovered until July 30, 2013. Because this was approximately 38 days before the event, it is impracticable to provide a full comment period due to lack of time... Department of Homeland Security Management Directive 023-01 and Commandant Instruction M16475.lD, which guide...

  10. Topography's event

    DEFF Research Database (Denmark)

    Munck Petersen, Rikke

    measure is not there alone since you measure it in something both visual, physical and shaped by views and ideas of society; something thought and abstract. Such knowledge point out the need for being able to measure other factors that visual and physical. Metrical and proportional view of the world seems...... - to stimulate and elaborate the event of conception and topological thinking....

  11. Topography's event

    DEFF Research Database (Denmark)

    Munck Petersen, Rikke

    The aim of the paper is first to discuss how horizon and scale can be understood, secondly how they differ and what they might have in common? If topography can be seen as a way of working with these relations experiences, creations and latencies? Thirdly if diagrams and diagrammatology can bring...... - to stimulate and elaborate the event of conception and topological thinking....

  12. Aquatic chemistry of flood events

    Science.gov (United States)

    Klavins, Maris; Rodinov, Valery

    2015-04-01

    During flood events a major discharge of water and dissolved substances happens. However flood waters very much differs from water composition during low-water events. Aquatic chemistry of flood waters also is of importance at the calculation of loadings as well as they might have major impact on water quality in receiving water bodies (lakes, coastal waters and seas). Further flood regime of rivers is subjected to changes due to climate change and growing impact of human activities. The aim of this study is to analyse water chemical composition changes during flood events in respect to low water periods, character of high-water events and characteristics of the corresponding basin. Within this study, the concentrations of major dissolved substances in the major rivers of Latvia have been studied using monitoring data as well as field studies during high water/ low water events. As territories of studies flows of substances in river basins/subbasins with different land-use character and different anthropogenic impacts has been studied to calculate export values depending on the land-use character. Impact of relations between dissolved substances and relations in respect to budgets has been calculated. The dynamics of DOC, nutrient and major dissolved substance flows depending on landuse pattern and soil properties in Latvia has been described, including emissions by industrial and agricultural production. In these changes evidently climate change signals can be identified. The water chemistry of a large number of rivers during flood events has been determined and the possible impact of water chemical composition on DOC and nutrient flows has been evaluated. Long-term changes (1977-2013) of concentrations of dissolved substances do not follow linear trends but rather show oscillating patterns, indicating impact of natural factors, e.g. changing hydrological and climatic conditions. There is a positive correlation between content of inert dissolved substances and

  13. A very unusual precipitation event associated with the 2015 floods in Jakarta: an analysis of the meteorological factors

    Directory of Open Access Journals (Sweden)

    Siswanto

    2017-06-01

    Full Text Available “The 2–days precipitation event over Jakarta in February 2015 was very unusual, the highest in the 135–year long historical records with a return period more than 60 years in the current climate. An intensified monsoon with an unusual northerly winds leading to this event is described. The 2015 event has become about 2.2 times more likely due to the trend towards more extreme precipitation.”

  14. Forecasting Turbine Icing Events

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik

    2012-01-01

    In this study, we present a method for forecasting icing events. The method is validated at two European wind farms in with known icing events. The icing model used was developed using current ice accretion methods, and newly developed ablation algorithms. The model is driven by inputs from the WRF...... mesoscale model, allowing for both climatological estimates of icing and short term icing forecasts. The current model was able to detect periods of icing reasonably well at the warmer site. However at the cold climate site, the model was not able to remove ice quickly enough leading to large ice...... accumulations, which have not been seen in observations. In addition to the model evaluation we were able to investigate the potential occurrence of ice induced power loss at two wind parks in Europe using observed data. We found that the potential loss during an icing event is large even when the turbine...

  15. Forecasting Turbine Icing Events

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik

    In this study, we present a method for forecasting icing events. The method is validated at two European wind farms in with known icing events. The icing model used was developed using current ice accretion methods, and newly developed ablation algorithms. The model is driven by inputs from the WRF...... mesoscale model, allowing for both climatological estimates of icing and short term icing forecasts. The current model was able to detect periods of icing reasonably well at the warmer site. However at the cold climate site, the model was not able to remove ice quickly enough leading to large ice...... accumulations, which have not been seen in observations. In addition to the model evaluation we were able to investigate the potential occurrence of ice induced power loss at two wind parks in Europe using observed data. We found that the potential loss during an icing event is large even when the turbine...

  16. Effect of dronedarone on cardiovascular events in atrial fibrillation

    DEFF Research Database (Denmark)

    Hohnloser, Stefan H; Crijns, Harry J G M; van Eickels, Martin

    2009-01-01

    BACKGROUND: Dronedarone is a new antiarrhythmic drug that is being developed for the treatment of patients with atrial fibrillation. METHODS: We conducted a multicenter trial to evaluate the use of dronedarone in 4628 patients with atrial fibrillation who had additional risk factors for death....... Patients were randomly assigned to receive dronedarone, 400 mg twice a day, or placebo. The primary outcome was the first hospitalization due to cardiovascular events or death. Secondary outcomes were death from any cause, death from cardiovascular causes, and hospitalization due to cardiovascular events....... RESULTS: The mean follow-up period was 21+/-5 months, with the study drug discontinued prematurely in 696 of the 2301 patients (30.2%) receiving dronedarone and in 716 of the 2327 patients (30.8%) receiving placebo, mostly because of adverse events. The primary outcome occurred in 734 patients (31...

  17. Event Index - a LHCb Event Search System

    CERN Document Server

    INSPIRE-00392208; Kazeev, Nikita; Redkin, Artem

    2015-12-23

    LHC experiments generate up to $10^{12}$ events per year. This paper describes Event Index - an event search system. Event Index's primary function is quickly selecting subsets of events from a combination of conditions, such as the estimated decay channel or stripping lines output. Event Index is essentially Apache Lucene optimized for read-only indexes distributed over independent shards on independent nodes.

  18. Predictors of recurrent events in patients with cryptogenic stroke and patent foramen ovale within the CLOSURE I (Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale) trial.

    Science.gov (United States)

    Elmariah, Sammy; Furlan, Anthony J; Reisman, Mark; Burke, David; Vardi, Moshe; Wimmer, Neil J; Ling, Shuqiong; Chen, Xiaohua; Kent, David M; Massaro, Joseph; Mauri, Laura

    2014-08-01

    This study sought to identify predictors of recurrent ischemic neurologic events within the CLOSURE I (Evaluation of the STARFlex Septal Closure System in Patients With a Stroke and/or Transient Ischemic Attack Due to Presumed Paradoxical Embolism Through a Patent Foramen Ovale) trial. The CLOSURE I trial found that transcatheter patent foramen ovale (PFO) closure using the STARFlex device was not superior to medical therapy in patients with cryptogenic stroke or transient ischemic attack (TIA) and PFO. The CLOSURE I trial is a multicenter, randomized trial of transcatheter PFO closure compared with medical therapy in patients who presented with cryptogenic stroke or TIA and had a PFO. We identified clinical predictors of recurrent ischemic stroke or TIA during 2 years of follow-up using Cox proportional hazards regression within the pooled intention-to-treat cohort. In 909 patients, the incidence of recurrent events was 5.7% with 25 patients suffering a recurrent stroke and 30 a TIA. Patients who had a recurrent event had higher body mass index (30.2 ± 6.2 vs. 28.3 ± 5.8%; p = 0.03) and more frequently had diabetes (19.2% vs. 7.1%; p = 0.0016), hypertension (46.2% vs. 30.1%; p = 0.015), and ischemic heart disease (3.8% vs. 0.9%; p = 0.05). Diabetes (hazard ratio [HR]: 3.39; 95% confidence interval [CI]: 1.69 to 6.84; p = 0.0007), index TIA (HR vs. stroke: 2.13; 95% CI: 1.20 to 3.80; p = 0.01), and the detection of atrial fibrillation after study enrollment (HR: 4.85; 95% CI: 2.05 to 11.47; p = 0.0003) independently predicted recurrent ischemic neurologic events. Recurrent neurologic events were more frequent in subjects with RoPE (Risk of Paradoxical Embolism) score ≤5 than those with >5 (14.5% vs. 4.2%; p Patent Foramen Ovale (PFO) [CLOSURE I]; NCT00201461). Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  19. Period Variations of RT Persei

    OpenAIRE

    Chun-Hwey Kim

    1995-01-01

    RT Per has been known as a close binary of which the orbital period has unpredictably varied so far. Although there are no agreements with the working mechanism for the changes of the period, two interpretations have been suggested and waiting for to be tested: 1)light-time effects due to the unseen 3rd and 4th bodies (Panchatsaram 1981), 2)Abrupt period-change due to internal variations of the system(e.q. mass transfer or mass loss) superimposing to the light-times effect by a 3rd body (Frie...

  20. Events diary

    Science.gov (United States)

    2000-01-01

    as Imperial College, the Royal Albert Hall, the Royal College of Art, the Natural History and Science Museums and the Royal Geographical Society. Under the heading `Shaping the future together' BA2000 will explore science, engineering and technology in their wider cultural context. Further information about this event on 6 - 12 September may be obtained from Sandra Koura, BA2000 Festival Manager, British Association for the Advancement of Science, 23 Savile Row, London W1X 2NB (tel: 0171 973 3075, e-mail: sandra.koura@britassoc.org.uk ). Details of the creating SPARKS events may be obtained from creating.sparks@britassoc.org.uk or from the website www.britassoc.org.uk . Other events 3 - 7 July, Porto Alegre, Brazil VII Interamerican conference on physics education: The preparation of physicists and physics teachers in contemporary society. Info: IACPE7@if.ufrgs.br or cabbat1.cnea.gov.ar/iacpe/iacpei.htm 27 August - 1 September, Barcelona, Spain GIREP conference: Physics teacher education beyond 2000. Info: www.blues.uab.es/phyteb/index.html

  1. "Ictal" lateralized periodic discharges.

    Science.gov (United States)

    Sen-Gupta, Indranil; Schuele, Stephan U; Macken, Micheal P; Kwasny, Mary J; Gerard, Elizabeth E

    2014-07-01

    adjusted). When defined by the presence of a time-locked clinical correlate, ILPDs appear to be strongly associated with a central EEG localization. This is likely due to cortical irritability in central head regions having greater propensity to manifest with positive, clinically apparent, and time-locked symptoms. Thus, dichotomization of ILPDs and NILPDs on this basis principally reflects differences in underlying anatomical locations of the periodic discharges rather than providing a clinically salient categorization. Copyright © 2014 Elsevier Inc. All rights reserved.

  2. Determining Optimal Machine Replacement Events with Periodic Inspection Intervals

    Science.gov (United States)

    2013-03-01

    Steven M. Cox. “Stochastic Models for Degradation- Based Reliability”, IIE Transactions , 37:533–542, 2005. [8] Kharoufeh, Jeffrey P., Daniel E...Kharoufeh, Jeffrey P., Christopher J. Solo, and M. Yasin Ulukus. “Semi-Markov Models for Degredation-Based Reliability”, IIE Transactions , 42:599–612...Prognostic Degradation Models for Computing and Updating Residual Life Distributions in Time-Varying Environments”, IEEE Transactions on

  3. Perfluoroctano líquido como tamponante vitreorretiniano de curta duração no pós-operatório de portadores de descolamento de retina por ruptura gigante Perfluoroctane liquid as a short-term vitreous-retinal tamponade in the postoperative period in patients with retinal detachment due to giant tears

    Directory of Open Access Journals (Sweden)

    Marcelo Carvalho Ventura

    2007-06-01

    Full Text Available OBJETIVOS: Relatar os resultados de vitrectomia via pars plana com utilização de perfluocarbono líquido (Perfluoroctano-Ophtalmos®, como tamponante vítreo-retiniano de curta duração, no pós-operatório de portadores de descolamento de retina, por ruptura gigante. MÉTODOS: Estudaram-se dez desses pacientes. Todos os casos eram complicados por vitreorretinopatia proliferativa grau B ou pior com rupturas que variavam em extensão de 90º a 210º. O perfluorocarbono líquido foi introduzido, por via pars plana, com o volume necessário para ultrapassar o limite posterior da ruptura, permanecendo no pós-operatório por cinco dias, estando os pacientes em decúbito dorsal. Após esse período submetiam-se a segunda intervenção para troca do perfluorocarbono líquido para gás ou óleo de silicone. RESULTADOS: Após período de acompanhamento médio de 16,2 ± 12,4 meses (2 a 43 meses, 80% das retinas estavam aplicadas, sendo necessária a repetição desta técnica em 1 caso (10% caso e em 2 casos (20% não houve reaplicação da retina por vitreorretinopatia avançada. Houve melhora da acuidade visual em 5 casos (50%. CONCLUSÃO: Observaram-se bons resultados quanto à aplicação da retina (80% e melhora da acuidade visual (50% quando do uso do perfluorocarbono líquido como tamponante vitreorretiniano de curta duração no pós-operatório de cirurgias de descolamento de retina por rupturas gigantes.PURPOSE: To report pars plana vitrectomy results of intravitreous use of liquid perfluorocarbon as a short-term postoperative tamponade in retinal detachment due to giant tears in a series of patients. METHODS: Ten of those patients, all of them complicated by proliferative vitreoretinopathy grade B or worse, with tear extension varying from 90º to 210º were studied. Perfluorocarbon liquid was injected via pars plana until the posterior tear limit, remaining in the postoperative period during five days, with the patients in supine position

  4. Absent menstrual periods - primary

    Science.gov (United States)

    Primary amenorrhea; No periods - primary; Absent periods - primary; Absent menses - primary; Absence of periods - primary ... nutrition Tumors In many cases, the cause of primary amenorrhea is not known.

  5. Electron–Ion Intensity Dropouts in Gradual Solar Energetic Particle Events during Solar Cycle 23

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Lun C., E-mail: ltan@umd.edu [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States)

    2017-09-01

    Since the field-line mixing model of Giacalone et al. suggests that ion dropouts cannot happen in the “gradual” solar energetic particle (SEP) event because of the large size of the particle source region in the event, the observational evidence of ion dropouts in the gradual SEP event should challenge the model. We have searched for the presence of ion dropouts in the gradual SEP event during solar cycle 23. From 10 SEP events the synchronized occurrence of ion and electron dropouts is identified in 12 periods. Our main observational facts, including the mean width of electron–ion dropout periods being consistent with the solar wind correlation scale, during the dropout period the dominance of the slab turbulence component and the enhanced turbulence power parallel to the mean magnetic field, and the ion gyroradius dependence of the edge steepness in dropout periods, are all in support of the solar wind turbulence origin of dropout events. Also, our observation indicates that a wide longitude distribution of SEP events could be due to the increase of slab turbulence fraction with the increased longitude distance from the flare-associated active region.

  6. CRITICAL EVENTS IN CONSTRUCTION PROCESS

    DEFF Research Database (Denmark)

    Jørgensen, Kirsten; Rasmussen, Grane Mikael Gregaard

    2009-01-01

    the building process and includes all participants in the construction project. A general result from the analysis was that critical events that occurred when the site was not using Lean Construction evolved much longer than critical events that occurred in the period when Lean Construction was used. Another......Function failures, defects and poor communication are major problems in the construction industry. These failures and defects are caused by a row of critical events in the construction process. The purpose of this paper is to define “critical events” in the construction process and to investigate...

  7. Evolution of periodicity in periodical cicadas.

    Science.gov (United States)

    Ito, Hiromu; Kakishima, Satoshi; Uehara, Takashi; Morita, Satoru; Koyama, Takuya; Sota, Teiji; Cooley, John R; Yoshimura, Jin

    2015-09-14

    Periodical cicadas (Magicicada spp.) in the USA are famous for their unique prime-numbered life cycles of 13 and 17 years and their nearly perfectly synchronized mass emergences. Because almost all known species of cicada are non-periodical, periodicity is assumed to be a derived state. A leading hypothesis for the evolution of periodicity in Magicicada implicates the decline in average temperature during glacial periods. During the evolution of periodicity, the determinant of maturation in ancestral cicadas is hypothesized to have switched from size dependence to time (period) dependence. The selection for the prime-numbered cycles should have taken place only after the fixation of periodicity. Here, we build an individual-based model of cicadas under conditions of climatic cooling to explore the fixation of periodicity. In our model, under cold environments, extremely long juvenile stages lead to extremely low adult densities, limiting mating opportunities and favouring the evolution of synchronized emergence. Our results indicate that these changes, which were triggered by glacial cooling, could have led to the fixation of periodicity in the non-periodical ancestors.

  8. Event dependent sampling of recurrent events

    DEFF Research Database (Denmark)

    Kvist, Tine Kajsa; Andersen, Per Kragh; Angst, Jules

    2010-01-01

    The effect of event-dependent sampling of processes consisting of recurrent events is investigated when analyzing whether the risk of recurrence increases with event count. We study the situation where processes are selected for study if an event occurs in a certain selection interval. Motivation...

  9. Future Events

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2010-04-01

    ://www.amc.edu/Academic/CME/ Upcoming_ Events.html QCLG-meeting 2011 26 November 2011, 29 November 2011 Brussels, Belgium URL: http://www.enfsi.eu/page.php?uid=2 ENFSI Joint Meeting 01 December 2011, 02 December 2011 The Hague (NFI, The Netherlands URL: http://www.enfsi.eu/page.php?uid=2 Bloodstain Pattern Recognition - Basic course 05 December 2011, 09 December 2011 The Hague, The Netherlands URL: http://www.enfsi.eu/page.php?uid= Expert Witness Intensive Training Course - 2 Day December 8th to 9th 2011 United Kingdom /London URL: http://www.healthcareconferencesuk.co.uk/ expert_witness 6th USA Pacific Medical & Legal Conference December 13th to 20th 2011 New York /USA URL: http://www.conferences21 .com/index.php? menu=home 12th Annual Multispecialty Conference on Medical Negligence & Risk Management in Medicine, Surgery, Emergency Medicine, Radiology & Family Medicine January 5th to 8th 2012 Costa Rica / URL http://www.bumc.bu.edu/cme/educational-opportunities/live-meetings/oblawl2/ 16th Annual Europe Pacific Medical & Legal Conference January 8th to 15th 2012 Italy /Cortina D’Ampezzo URL: http://www.conferences21.com/index.php? menu = home 3rd International Workshop on Medical Image Analysis and Description for Diagnosis Systems(MIAD 2012 1- 4 February 2012 Vilamoura, Algarve, Portugal URL: http://www.biostec.org/MIAD.asp 3rd International Conference on Current Trends in Forensic Sciences, Forensic Medicine & Toxicology February 3rd to 5th 2012 India /Jaipur URL: http://www.iamleconf.in/home 3rd International Conference on Legal Medicine, Medical Negligence & Litigation in Medical Practice February 3rd to 5th 2012 India /Jaipur URL http://www.iamleconf.in/ 12th Annual Pan Europe Pacific Medical & Legal Conference February 5th to 12th 2012 France /Paris URL: http://www.conferences21.com/index.php? menu=home American College of Legal Medicine 2012 Annual Conference February 23rd to 26th 2012 Louisiana /New Orleans USA URL: http://www.aclm.org/

  10. Event Index - an LHCb Event Search System

    CERN Document Server

    Ustyuzhanin, Andrey

    2015-01-01

    During LHC Run 1, the LHCb experiment recorded around 1011 collision events. This paper describes Event Index | an event search system. Its primary function is to quickly select subsets of events from a combination of conditions, such as the estimated decay channel or number of hits in a subdetector. Event Index is essentially Apache Lucene [1] optimized for read-only indexes distributed over independent shards on independent nodes.

  11. Vaccine Adverse Events

    Science.gov (United States)

    ... Biologics Evaluation & Research Vaccine Adverse Events Vaccine Adverse Events Share Tweet Linkedin Pin it More sharing options ... the primary immunization series in infants Report Adverse Event Report a Vaccine Adverse Event Contact FDA (800) ...

  12. Gastrointestinal events with clopidogrel

    DEFF Research Database (Denmark)

    Grove, Erik Lerkevang; Würtz, Morten; Schwarz, Peter

    2013-01-01

    Clopidogrel prevents cardiovascular events, but has been linked with adverse gastrointestinal (GI) complications, particularly bleeding events.......Clopidogrel prevents cardiovascular events, but has been linked with adverse gastrointestinal (GI) complications, particularly bleeding events....

  13. A highly specific test for periodicity

    Energy Technology Data Exchange (ETDEWEB)

    Ansmann, Gerrit, E-mail: gansmann@uni-bonn.de [Department of Epileptology, University of Bonn, Sigmund-Freud-Straße 25, 53105 Bonn (Germany); Helmholtz Institute for Radiation and Nuclear Physics, University of Bonn, Nussallee 14–16, 53115 Bonn (Germany); Interdisciplinary Center for Complex Systems, University of Bonn, Brühler Straße 7, 53175 Bonn (Germany)

    2015-11-15

    We present a method that allows to distinguish between nearly periodic and strictly periodic time series. To this purpose, we employ a conservative criterion for periodicity, namely, that the time series can be interpolated by a periodic function whose local extrema are also present in the time series. Our method is intended for the analysis of time series generated by deterministic time-continuous dynamical systems, where it can help telling periodic dynamics from chaotic or transient ones. We empirically investigate our method's performance and compare it to an approach based on marker events (or Poincaré sections). We demonstrate that our method is capable of detecting small deviations from periodicity and outperforms the marker-event-based approach in typical situations. Our method requires no adjustment of parameters to the individual time series, yields the period length with a precision that exceeds the sampling rate, and its runtime grows asymptotically linear with the length of the time series.

  14. Creating Special Events

    Science.gov (United States)

    deLisle, Lee

    2009-01-01

    "Creating Special Events" is organized as a systematic approach to festivals and events for students who seek a career in event management. This book looks at the evolution and history of festivals and events and proceeds to the nuts and bolts of event management. The book presents event management as the means of planning, organizing, directing,…

  15. The ISC Seismic Event Bibliography

    Science.gov (United States)

    Di Giacomo, Domenico; Storchak, Dmitry

    2015-04-01

    The International Seismological Centre (ISC) is a not-for-profit organization operating in the UK for the last 50 years and producing the ISC Bulletin - the definitive worldwide summary of seismic events, both natural and anthropogenic - starting from the beginning of 20th century. Often researchers need to gather information related to specific seismic events for various reasons. To facilitate such task, in 2012 we set up a new database linking earthquakes and other seismic events in the ISC Bulletin to bibliographic records of scientific articles (mostly peer-reviewed journals) that describe those events. Such association allows users of the ISC Event Bibliography (www.isc.ac.uk/event_bibliography/index.php) to run searches for publications via a map-based web interface and, optionally, selecting scientific publications related to either specific events or events in the area of interest. Some of the greatest earthquakes were described in several hundreds of articles published over a period of few years. The journals included in our database are not limited to seismology but bring together a variety of fields in geosciences (e.g., engineering seismology, geodesy and remote sensing, tectonophysics, monitoring research, tsunami, geology, geochemistry, hydrogeology, atmospheric sciences, etc.) making this service useful in multidisciplinary studies. Usually papers dealing with large data set are not included (e.g., papers describing a seismic catalogue). Currently the ISC Event Bibliography includes over 17,000 individual publications from about 500 titles related to over 14,000 events that occurred in last 100+ years. The bibliographic records in the Event Bibliography start in the 1950s, and it is updated as new publications become available.

  16. Urticaria due to antihistamines

    National Research Council Canada - National Science Library

    Sánchez Morillas, L; Rojas Pérez-Ezquerra, P; Reaño Martos, M; Sanz, M L; Laguna Martínez, J J

    2011-01-01

    .... We report a patient with urticaria due to ingestion of ebastine and fexofenadine. Skin prick tests, patch tests, and basophil activation tests with the implicated drugs and antihistamines from other families were negative...

  17. Towards cross-lingual alerting for bursty epidemic events

    Directory of Open Access Journals (Sweden)

    Collier Nigel

    2011-10-01

    Full Text Available Abstract Background Online news reports are increasingly becoming a source for event-based early warning systems that detect natural disasters. Harnessing the massive volume of information available from multilingual newswire presents as many challanges as opportunities due to the patterns of reporting complex spatio-temporal events. Results In this article we study the problem of utilising correlated event reports across languages. We track the evolution of 16 disease outbreaks using 5 temporal aberration detection algorithms on text-mined events classified according to disease and outbreak country. Using ProMED reports as a silver standard, comparative analysis of news data for 13 languages over a 129 day trial period showed improved sensitivity, F1 and timeliness across most models using cross-lingual events. We report a detailed case study analysis for Cholera in Angola 2010 which highlights the challenges faced in correlating news events with the silver standard. Conclusions The results show that automated health surveillance using multilingual text mining has the potential to turn low value news into high value alerts if informed choices are used to govern the selection of models and data sources. An implementation of the C2 alerting algorithm using multilingual news is available at the BioCaster portal http://born.nii.ac.jp/?page=globalroundup.

  18. MGR External Events Hazards Analysis

    Energy Technology Data Exchange (ETDEWEB)

    L. Booth

    1999-11-06

    The purpose and objective of this analysis is to apply an external events Hazards Analysis (HA) to the License Application Design Selection Enhanced Design Alternative 11 [(LADS EDA II design (Reference 8.32))]. The output of the HA is called a Hazards List (HL). This analysis supersedes the external hazards portion of Rev. 00 of the PHA (Reference 8.1). The PHA for internal events will also be updated to the LADS EDA II design but under a separate analysis. Like the PHA methodology, the HA methodology provides a systematic method to identify potential hazards during the 100-year Monitored Geologic Repository (MGR) operating period updated to reflect the EDA II design. The resulting events on the HL are candidates that may have potential radiological consequences as determined during Design Basis Events (DBEs) analyses. Therefore, the HL that results from this analysis will undergo further screening and analysis based on the criteria that apply during the performance of DBE analyses.

  19. Data on mortality from external causes and events of undetermined intent, Parana State, Brazil, 1979 to 2005

    OpenAIRE

    de Lozada, EMK; Mathias, TAD; de Andrade, SM; AIDAR, T.

    2009-01-01

    This study analyzed the quality of data from the Mortality Information System (SIM) for deaths due to external causes in the State of Parana, Brazil, 1979 to 2005, focusing on events of undetermined intent. Deaths were grouped in motor vehicle accidents, homicides, suicides, and events of undetermined intent, and proportional mortality and relative annual variation of rates over the three-year period were analyzed. Motor vehicle accidents (more than 30% of the total) were the most frequent ca...

  20. Adolescents' Evaluation of Cyberbullying Events

    Science.gov (United States)

    Gomez-Garibello, Carlos; Shariff, Shaheen; McConnell, Megan; Talwar, Victoria

    2012-01-01

    Educators and other professionals working with adolescents have grown increasingly concerned about how technology affects social relationships given the amount of time that is spent engaging in online activities. Cyberbullying has sparked the interest of many researchers due to the tragic events reported in the media, relating to the online…

  1. Periodicity of extinction: A 1988 update

    Science.gov (United States)

    Sepkowski, J. John, Jr.

    1988-01-01

    The hypothesis that events of mass extinction recur periodically at approximately 26 my intervals is an empirical claim based on analysis of data from the fossil record. The hypothesis has become closely linked with catastrophism because several events in the periodic series are associated with evidence of extraterrestrial impacts, and terrestrial forcing mechanisms with long, periodic recurrences are not easily conceived. Astronomical mechanisms that have been hypothesized include undetected solar companions and solar oscillation about the galactic plane, which induce comet showers and result in impacts on Earth at regular intervals. Because these mechanisms are speculative, they have been the subject of considerable controversy, as has the hypothesis of periodicity of extinction. In response to criticisms and uncertainties, a data base was developed on times of extinction of marine animal genera. A time series is given and analyzed with 49 sample points for the per-genus extinction rate from the Late Permian to the Recent. An unexpected pattern in the data is the uniformity of magnitude of many of the periodic extinction events. Observations suggest that the sequence of extinction events might be the result of two sets of mechanisms: a periodic forcing that normally induces only moderate amounts of extinction, and independent incidents or catastrophes that, when coincident with the periodic forcing, amplify its signal and produce major-mass extinctions.

  2. Monitoring of Drought Events in Gorontalo Regency

    Science.gov (United States)

    Koem, S.; Rusiyah

    2017-12-01

    Gorontalo Regency is a region vulnerable to drought. Drought is one of meteorological disaster because it tends to bring negative impact on various sectors. This study used rainfall data from 1981 to 2016 (35 years). The research employed Standardized Precipitation Index (SPI) to monitor and calculate the level of drought from the duration, intensity, and frequency in different time scales. The SPI value was calculated using the DrinC and ArcGIS software is used to create drought spatial distribution maps. The mean intensity of drought simultaneously followed the drought magnitude in Bilato station. The peak of drought in SPI-3 occurs in 1982, 2009 and 2016. In 1982, about 76.5% of the stations showed that the peak of drought events for SPI-3 in October to December. Moreover, 94% of the stations reveals that the peak of drought events for SPI-6 occur in July to December 1982. This shows that drought in 1982 was more severe than other years in the last three decades. Linear trends of drought for the period of 1981 to 2016 in most stations show an increasing trend, hence, it can be concluded that Gorontalo Regency experienced an increase in the wet period. Changes in time-scale caused the tendency for a high number of dry period frequencies. Drought spatial distribution could be used to determine the priority plans in finding the solutions due to droughts that occur in drought-vulnerable areas. Drought analysis using SPI could contribute to the decision-making in the future as an effort to minimize the impact of drought.

  3. National Special Security Events

    National Research Council Canada - National Science Library

    Reese, Shawn

    2007-01-01

    ...) as National Special Security Events (NSSE) Beginning in September 1998 through February 2007, there have been 27 events designated as NSSEs Some of these events have included presidential inaugurations, presidential nominating conventions...

  4. [People with stomas - issues and responses in critical periods].

    Science.gov (United States)

    Aoki, Kazue; Ishiguro, Miho

    2014-01-01

    People with stomas who have either been cured of cancer or are living with cancer have achieved good interrelationships among the three issues of"establishing self-care","dealing with stoma complications", and"accepting stomas", and they are maintaining stable physical and mental states.However, self-care may become difficult due to stoma complications and adverse events caused by chemotherapy and radiation therapy in the cancer treatment period, and in advanced phases of cancer serious stoma complications may occur due to deterioration of general condition and advancing cancer. Therefore, there is a risk that those stable physical and mental states will collapse.In order to deal with this critical state, in the cancer treatment period, stoma skin care is used for handling skin problems around the stoma, and for adverse events such as hand-and-foot syndrome, braces that are easy to operate are chosen from among various types of stoma braces in order to cover impediments.During advanced phases of cancer, care is conducted with the main priority placed on physical stability in order to ensure that the three major complications of stoma varicose veins, stoma prolapse, and parastomal hernia do not worsen and significantly affect general condition and daily life.Stoma outpatient treatment that provides lifelong support for such issues, and the existence of skin- and excretion-care certified nurses who provided highly specialized selfcare support, are extremely important for cancer survivors with stomas.

  5. Death due to asthma

    Directory of Open Access Journals (Sweden)

    Albert L. Sheffer

    1996-01-01

    Full Text Available The prevalence and fatality rate of asthma have increased worldwide. Underdiagnosis and undertreatment of asthma are central to the occurrence of fatal asthma. Atopy is the principal risk factor associated with asthma. However, consideration of the epidemiologic, physiologic, pharmacologic, pathologic and clinical parameters of asthma assessment may provide valuable insight into death due to asthma. Psychologic and socioeconomic factors may further aggravate the asthma status. Ethnic minorities are at increased risk of asthma. The perception of dyspnea may be blunted in asthma sufferers. Slow-onset fatal asthma may be associated with submucosal eosinophilic, whereas sudden-onset may be associated with submucosal neutrophilia. Fatal asthma occurs in patients abusing regular |32-agonist therapy. Peak flow assessment often provides insight into asthma deterioration prior to signs of respiratory distress. Markers of risk of death due to asthma further identify the fatality-prone asthma patient.

  6. Period Variations of RT Persei

    Directory of Open Access Journals (Sweden)

    Chun-Hwey Kim

    1995-12-01

    Full Text Available RT Per has been known as a close binary of which the orbital period has unpredictably varied so far. Although there are no agreements with the working mechanism for the changes of the period, two interpretations have been suggested and waiting for to be tested: 1light-time effects due to the unseen 3rd and 4th bodies (Panchatsaram 1981, 2Abrupt period-change due to internal variations of the system(e.q. mass transfer or mass loss superimposing to the light-times effect by a 3rd body (Frieboes-Conde & Herczeg 1973. In the point of view that the former interprepation models could predict the behavior of the changes of the orbital period theoretically, we checked whether the recent observed times of minimum lights follow the predictions by the first model or not. We confirmed that the observed times of minimum lights have followed the variations calculated by the light-times effects due to 3rd and 4th bodies suggested by Panchatsaram. In this paper a total of 626 times of minimum lights were reanalyzed in terms of the light-time effects by the 3rd and 4th bodies. We concluded that the eclipsing pair in SV Cam system moves in an elliptic orbit about center of mass of the triple system with a period of about 42.y2, while the mass center of the triplet is in light-time orbit about the center of mass of the quadruple system with a period of 120y. The mean masses deduced for the 3rd and 4th bodies were 0.89m⨀ and 0.82m⨀, respectively.

  7. Death due to asthma

    OpenAIRE

    Sheffer, Albert L.

    1996-01-01

    The prevalence and fatality rate of asthma have increased worldwide. Underdiagnosis and undertreatment of asthma are central to the occurrence of fatal asthma. Atopy is the principal risk factor associated with asthma. However, consideration of the epidemiologic, physiologic, pharmacologic, pathologic and clinical parameters of asthma assessment may provide valuable insight into death due to asthma. Psychologic and socioeconomic factors may further aggravate the asthma status. Ethnic minoriti...

  8. Human due diligence.

    Science.gov (United States)

    Harding, David; Rouse, Ted

    2007-04-01

    Most companies do a thorough job of financial due diligence when they acquire other companies. But all too often, deal makers simply ignore or underestimate the significance of people issues in mergers and acquisitions. The consequences are severe. Most obviously, there's a high degree of talent loss after a deal's announcement. To make matters worse, differences in decision-making styles lead to infighting; integration stalls; and productivity declines. The good news is that human due diligence can help companies avoid these problems. Done early enough, it helps acquirers decide whether to embrace or kill a deal and determine the price they are willing to pay. It also lays the groundwork for smooth integration. When acquirers have done their homework, they can uncover capability gaps, points of friction, and differences in decision making. Even more important, they can make the critical "people" decisions-who stays, who goes, who runs the combined business, what to do with the rank and file-at the time the deal is announced or shortly thereafter. Making such decisions within the first 30 days is critical to the success of a deal. Hostile situations clearly make things more difficult, but companies can and must still do a certain amount of human due diligence to reduce the inevitable fallout from the acquisition process and smooth the integration. This article details the steps involved in conducting human due diligence. The approach is structured around answering five basic questions: Who is the cultural acquirer? What kind of organization do you want? Will the two cultures mesh? Who are the people you most want to retain? And how will rank-and-file employees react to the deal? Unless an acquiring company has answered these questions to its satisfaction, the acquisition it is making will be very likely to end badly.

  9. [Onychomycoses due to molds].

    Science.gov (United States)

    Chabasse, D; Pihet, M

    2014-12-01

    Onychomycoses represent about 30% of superficial mycosis that are encountered in Dermatology consults. Fungi such as dermatophytes, which are mainly found on the feet nails, cause nearly 50% of these onychopathies. Yeasts are predominantly present on hands, whereas non-dermatophytic moulds are very seldom involved in both foot and hand nails infections. According to literature, these moulds are responsible for 2 to 17% of onychomycoses. Nevertheless, we have to differentiate between onychomycoses due to pseudodermatophytes such as Neoscytalidium (ex-Scytalidium) and Onychocola canadensis, which present a high affinity for keratin, and onychomycoses due to filamentous fungi such as Aspergillus, Fusarium, Scopulariopsis, Acremonium... These saprophytic moulds are indeed most of the time considered as colonizers rather than real pathogens agents. Mycology and histopathology laboratories play an important role. They allow to identify the species that is involved in nail infection, but also to confirm parasitism by the fungus in the infected nails. Indeed, before attributing any pathogenic role to non-dermatophytic moulds, it is essential to precisely evaluate their pathogenicity through samples and accurate mycological and/or histological analysis. The treatment of onychomycoses due to non-dermatophytic moulds is difficult, as there is today no consensus. The choice of an antifungal agent will first depend on the species that is involved in the infection, but also on the severity of nail lesions and on the patient himself. In most cases, the onychomycosis will be cured with chemical or mechanical removing of the infected tissues, followed by a local antifungal treatment. In some cases, a systemic therapy will be discussed. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  10. A statistical framework for conditional extreme event attribution

    Science.gov (United States)

    Yiou, Pascal; Jézéquel, Aglaé; Naveau, Philippe; Otto, Frederike E. L.; Vautard, Robert; Vrac, Mathieu

    2017-04-01

    The goal of the attribution of individual events is to estimate whether and to what extent the probability of an extreme climate event evolves when external conditions (e.g., due to anthropogenic forcings) change. Many types of climate extremes are linked to the variability of the large-scale atmospheric circulation. It is hence essential to decipher the roles of atmospheric variability and increasing mean temperature in the change of probabilities of extremes. It is also crucial to define a background state (or counterfactual) to which recent observations are compared. In this paper we present a statistical framework to determine the dynamical (linked to the atmospheric circulation) and thermodynamical (linked to slow forcings) contributions to the probability of extreme climate events. We illustrate this methodology on a record precipitation event that hit southern United Kingdom in January 2014. We compare possibilities for the creation of two states (or worlds) in which probability change is determined. These two worlds are defined in a large ensemble of atmospheric model simulations (Weather@Home factual and counterfactual simulations) and separate periods (new: 1951-2014, and old: 1900-1950) in reanalyses and observations. We discuss how the atmospheric circulation conditioning can affect the interpretation of extreme event attribution. We eventually show the qualitative coherence of results between the choice of worlds (factual/counterfactual vs. new/old).

  11. Severe accidents due to windsurfing in the Aegean Sea.

    Science.gov (United States)

    Kalogeromitros, A; Tsangaris, H; Bilalis, D; Karabinis, A

    2002-06-01

    Windsurfing is a popular sport and has recently become an Olympic event. As an open-air water activity that requires the participant to be in perfect physical condition, windsurfers may be prone to accidents when certain basic rules or procedures are violated. The current study monitored severe injuries due to windsurfing over a period of 12 months in the Aegean Sea in Greece. Our study revealed 22 cases of severe accidents due to windsurfing, with a wide range of injuries including head injuries, spinal cord injuries, and severe fractures of the extremities. Prolonged hospitalization, severe disability and two deaths occurred as consequences of these accidents. The study examined the characteristics of these patients and the possible risk factors and conditions associated with the accidents. We also focused on the most common types of injuries and reviewed the mechanisms that may provoke them. Water sports and particularly windsurfing represent a major challenge for the emergency medical system, especially in the Aegean Sea. Hundreds of islands, kilometres of isolated coasts, millions of tourists, an extended summer period and rapidly changing weather create conditions that constantly test the efficacy of the emergency services. The development of an appropriate infrastructure and maximum control of the risk factors causing these accidents could reduce the morbidity and mortality that, unfortunately but rather predictably, accompany this popular summer activity.

  12. Christmas: an event driven by our hormones?

    Science.gov (United States)

    Ludwig, M

    2011-12-01

    No other event in the Christian calendar has such a deep impact on our behaviour as the annual event called Christmas. Christmas is not just 'Christmas Day'; indeed, it is a long developmental rhythm with a period of almost exactly 365 days. Here, I describe the neuronal and hormonal changes and their effects on our behaviour during the preparation and the execution of the event(1) . © 2011 The Author. Journal of Neuroendocrinology © 2011 Blackwell Publishing Ltd.

  13. Tracking transient events through geosynchronous orbit

    DEFF Research Database (Denmark)

    Korotova, G.I.; Sibeck, D.G.; Moretto, T.

    1999-01-01

    Impulsive events in high-latitude dayside ground magnetograms provide evidence for one or more modes of unsteady solar wind-magnetosphere interaction. We use geosynchronous magnetic field and energetic electron observations to demonstrate that the events correspond to abrupt global variations...... during periods of orthospiral, duskward, and northward interplanetary magnetic field orientation. Event properties are consistent with an interpretation in terms of widespread solar wind pressure fronts striking the bow shock and magnetopause....

  14. [Childhood periodic syndromes].

    Science.gov (United States)

    Cuvellier, J-C; Lépine, A

    2010-01-01

    This review focuses on the so-called "periodic syndromes of childhood that are precursors to migraine", as included in the Second Edition of the International Classification of Headache Disorders. Three periodic syndromes of childhood are included in the Second Edition of the International Classification of Headache Disorders: abdominal migraine, cyclic vomiting syndrome and benign paroxysmal vertigo, and a fourth, benign paroxysmal torticollis is presented in the Appendix. The key clinical features of this group of disorders are the episodic pattern and intervals of complete health. Episodes of benign paroxysmal torticollis begin between 2 and 8 months of age. Attacks are characterized by an abnormal inclination and/or rotation of the head to one side, due to cervical dystonia. They usually resolve by 5 years. Benign paroxysmal vertigo presents as sudden attacks of vertigo, accompanied by inability to stand without support, and lasting seconds to minutes. Age at onset is between 2 and 4 years, and the symptoms disappear by the age of 5. Cyclic vomiting syndrome is characterized in young infants and children by repeated stereotyped episodes of pernicious vomiting, at times to the point of dehydration, and impacting quality of life. Mean age of onset is 5 years. Abdominal migraine remains a controversial issue and presents in childhood with repeated stereotyped episodes of unexplained abdominal pain, nausea and vomiting occurring in the absence of headache. Mean age of onset is 7 years. Both cyclic vomiting syndrome and abdominal migraine are noted for the absence of pathognomonic clinical features but also for the large number of other conditions to be considered in their differential diagnoses. Diagnostic criteria, such as those of the Second Edition of the International Classification of Headache Disorders and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, have made diagnostic approach and management easier. Their diagnosis

  15. Visual quasi-periodicity

    NARCIS (Netherlands)

    Pogalin, E.; Smeulders, A.W.M.; Thean, A.H.C.

    2008-01-01

    Periodicity is at the core of the recognition of many actions. This paper takes the following steps to detect and measure periodicity. 1) We establish a conceptual framework of classifying periodicity in 10 essential cases, the most important of which are flashing (of a traffic light), pulsing (of

  16. TECHNOLOGY OF EDUCATIONAL EVENTS DESIGNING

    Directory of Open Access Journals (Sweden)

    N. V. Volkova

    2017-01-01

    Full Text Available The aim of the article is to prove and disclose the essence of the author’s technology of educational events designing.Methodology and methods of research. Methodological basis of work is humanitarian approach. The method of pedagogical modeling was used for the model development of educational events influence on pedagogical activity formation. The content analysis of texts descriptions, case-study method, expert estimations of event projects were applied as the main methods of efficiency confirmation of the technology of educational events design.Results and scientific novelty. The characteristics of an educational event are emphasized by means of an empirical way: opening (what a person opens for himself; generation (a result of a personal action; and participation in creation of something "new" (new communications, relations and experience. The structure of technology of educational events design including work with concepts (an educational event, substantial and procedural components is presented. The technology of educational events designing is considered as the process of the well-grounded choice of designing technologies, mutual activity, pedagogical communication, components of educational activity: contents, methods, means, and organizational forms depending on educational aims due to age-specific peculiarities of participants of the educational event. The main conditions providing successful use of the technology are the involvement into joint cognitive activity of all its participants and importance of the events for each of them that qualitatively change the nature of a cognitive process and generate real transformations of the reality.Practical significance. The author’s experience in teaching testifies to introduction of the module «Technology of Design of Educational Events» into the basic educational subject-module «Design Competence of the Teacher» (degree program «Pedagogical Education», considering this module as

  17. Credit where due.

    Science.gov (United States)

    Friedman, Steven G

    2016-08-01

    The history of medicine is filled with stories of tireless researchers who failed to get credit for their hard work. Examples of this include Rosalind Franklin, who helped to elucidate the structure of DNA; Frederick Banting, who helped to discover insulin; and Jay McLean, who discovered heparin. The founding of the field of vascular surgery provides one of the most vivid examples of uncredited work. Even though Alexis Carrel was an unpaid, untitled assistant in Charles Guthrie's laboratory, it was Carrel alone who received a Nobel Prize for their work. In an attempt to give credit where due, the reasons for this injustice are described. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  18. Historically defined autobiographical periods

    DEFF Research Database (Denmark)

    Brown, Norman R.; Hansen, Tia G. B.; Lee, Peter J.

    2012-01-01

    over time and theoretical implications are discussed, notably by introducing a new approach to autobiographical memory, Transition Theory, which assumes that autobiographical memory is organized by transitional events that can be selfinitiated or externally imposed - historically defined...

  19. Periodic self-lensing from accreting massive black hole binaries

    Science.gov (United States)

    D'Orazio, Daniel J.; Di Stefano, Rosanne

    2018-03-01

    Nearly 150 massive black hole binary (MBHB) candidates at sub-pc orbital separations have been reported in recent literature. Nevertheless, the definitive detection of even a single such object remains elusive. If at least one of the black holes is accreting, the light emitted from its accretion disc will be lensed by the other black hole for binary orbital inclinations near to the line of sight. This binary self-lensing could provide a unique signature of compact MBHB systems. We show that, for MBHBs with masses in the range 106-1010 M⊙ and with orbital periods less than ˜10 yr, strong lensing events should occur in one to 10s of per cent of MBHB systems that are monitored for an entire orbit. Lensing events will last from days for the less massive, shorter period MBHBs to a year for the most massive ˜10 year orbital period MBHBs. At small inclinations of the binary orbit to the line of sight, lensing must occur and will be accompanied by periodicity due to the relativistic Doppler boost. Flares at the same phase as the otherwise average flux of the Doppler modulation would be a smoking gun signature of self-lensing and can be used to constrain binary parameters. For MBHBs with separation ≳100 Schwarzschild radii, we show that finite-sized source effects could serve as a probe of MBH accretion disc structure. Finally, we stress that our lensing probability estimate implies that ˜10 of the known MBHB candidates identified through quasar periodicity should exhibit strong lensing flares.

  20. Rain-on-snow events over North America based on two Canadian regional climate models

    Science.gov (United States)

    Il Jeong, Dae; Sushama, Laxmi

    2018-01-01

    This study evaluates projected changes to rain-on-snow (ROS) characteristics (i.e., frequency, rainfall amount, and runoff) for the future 2041-2070 period with respect to the current 1976-2005 period over North America using six simulations, based on two Canadian RCMs, driven by two driving GCMs for RCP4.5 and 8.5 emission pathways. Prior to assessing projected changes, the two RCMs are evaluated by comparing ERA-Interim driven RCM simulations with available observations, and results indicate that both models reproduce reasonably well the observed spatial patterns of ROS event frequency and other related features. Analysis of current and future simulations suggest general increases in ROS characteristics during the November-March period for most regions of Canada and for northwestern US for the future period, due to an increase in the rainfall frequency with warmer air temperatures in future. Future ROS runoff is often projected to increase more than future ROS rainfall amounts, particularly for northeastern North America, during snowmelt months, as ROS events usually accelerate snowmelt. The simulations show that ROS event is a primary flood generating mechanism over most of Canada and north-western and -central US for the January-May period for the current period and this is projected to continue in the future period. More focused analysis over selected basins shows decreases in future spring runoff due to decreases in both snow cover and ROS runoff. The above results highlight the need to take into consideration ROS events in water resources management adaptation strategies for future climate.

  1. Episodes, events, and models

    Directory of Open Access Journals (Sweden)

    Sangeet eKhemlani

    2015-10-01

    Full Text Available We describe a novel computational theory of how individuals segment perceptual information into representations of events. The theory is inspired by recent findings in the cognitive science and cognitive neuroscience of event segmentation. In line with recent theories, it holds that online event segmentation is automatic, and that event segmentation yields mental simulations of events. But it posits two novel principles as well: first, discrete episodic markers track perceptual and conceptual changes, and can be retrieved to construct event models. Second, the process of retrieving and reconstructing those episodic markers is constrained and prioritized. We describe a computational implementation of the theory, as well as a robotic extension of the theory that demonstrates the processes of online event segmentation and event model construction. The theory is the first unified computational account of event segmentation and temporal inference. We conclude by demonstrating now neuroimaging data can constrain and inspire the construction of process-level theories of human reasoning.

  2. [Keratitis due to Acanthamoeba].

    Science.gov (United States)

    Pérez-Irezábal, Julio; Martínez, Inés; Isasa, Patricia; Barrón, Jorge

    2006-10-01

    Free-living amebae appertaining to the genus Acanthamoeba, Naegleria and Balamuthia are the most prevalent protozoa found in the environment. These amebae have a cosmopolitan distribution in soil, air and water, providing multiple opportunities for contacts with humans and animals, although they only occasionally cause disease. Acanthamoeba spp. are the causative agent of granulomatous amebic encephalitis, a rare and often fatal disease of the central nervous system, and amebic keratitis, a painful disease of the eyes. Keratitis usually follows a chronic course due to the delay in diagnosis and subsequent treatment. The clear increase in Acanthamoeba keratitis in the last 20 years is related to the use and deficient maintenance of contact lenses, and to swimming while wearing them. The expected incidence is one case per 30,000 contact lens wearers per year, with 88% of cases occurring in persons wearing hydrogel lenses. This review presents information on the morphology, life-cycle and epidemiology of Acanthamoeba, as well as on diagnostic procedures (culture), appropriate antimicrobial therapy, and prevention measures.

  3. Second Period Access Report

    DEFF Research Database (Denmark)

    Maisondieu, Christophe; Giebhardt, Jochen; Tetu, Amelie

    The work described in this publication has received support from the European Community - Research Infrastructure Action under the FP7 “Capacities” Specific Programme through grant agreement number 262552, MaRINET. Project Periodic Report. 2nd Period: October 2012 – March 2014 inclusive.......The work described in this publication has received support from the European Community - Research Infrastructure Action under the FP7 “Capacities” Specific Programme through grant agreement number 262552, MaRINET. Project Periodic Report. 2nd Period: October 2012 – March 2014 inclusive....

  4. Painful menstrual periods

    Science.gov (United States)

    Menstruation - painful; Dysmenorrhea; Periods - painful; Cramps - menstrual; Menstrual cramps ... a few days during each menstrual cycle. Painful menstruation is the leading cause of lost time from ...

  5. Contrasting sulfur isotope records during the Late Devonian punctata and Upper Kellwasser events

    Science.gov (United States)

    Sim, M.; Ono, S.; Hurtgen, M. T.

    2013-12-01

    The Late Devonian was a period of intense biological and environmental changes, including terrestrial afforestation, a series of asteroid impacts, and active orogeny due to the accretion of continental blocks. High amplitude positive carbon isotope excursions, the punctata and Kellwasser events, reflect major perturbations in the global carbon cycle during this period, which have been attributed to increased continental weathering and subsequent ocean eutrophication. Despite the comparable carbon isotope anomalies, however, a global biological crisis has been reported only for the Kellwasser events, while very low extinction intensity characterizes the punctata Event. We will present sulfur isotope records of carbonate associated sulfate (CAS) and pyrite from Frasnian-Famennian sections in the Great Basin, USA, and evaluate the role of sulfur during the punctata and Upper Kellwasser events. A positive sulfur isotope shift in both CAS and pyrite accompanies the onset of the punctata Event, but with a larger extent in the latter. As a result, the sulfur isotope offset between CAS and pyrite (Δ34SCAS-py) plummeted to less than 10‰. In the middle of the punctata Event, a sharp negative δ34SCAS excursion occurred just after the Alamo Impact, leading to the negative Δ34SCAS-py values. Unlike the rapid oscillations of δ34Spy and δ34SCAS during the punctata Event, the Upper Kellwasser was a period of stability, except for a brief drop of δ34SCAS before the event. Paired sulfur isotope data, aided by a simple box model, suggests that geochemical cycle of sulfur might be responsible for the contrasting biological responses to these two events. Superheavy pyrite and high stratigraphic variability of δ34Spy and δ34SCAS demonstrate a relatively small oceanic sulfate pool during the punctata Event, and the Alamo Impact likely triggered to the rapid oxidation of microbially-produced sulfide. The expansion of sulfidic bottom water thus may have been impeded, thereby

  6. The Living Periodic Table

    Science.gov (United States)

    Nahlik, Mary Schrodt

    2005-01-01

    To help make the abstract world of chemistry more concrete eighth-grade students, the author has them create a living periodic table that can be displayed in the classroom or hallway. This display includes information about the elements arranged in the traditional periodic table format, but also includes visual real-world representations of the…

  7. On some periodicity effects

    DEFF Research Database (Denmark)

    Sorokin, Sergey V.

    2015-01-01

    The talk is concerned with the modelling of wave propagation in and vibration of periodic elastic structures. Although analysis of wave-guide properties of infinite periodic structures is a well establish research subject, some issues have not yet been fully addressed in the literature. The aim...... of the talk is to illustrate these issues in simple examples and to discuss possible applications and generalisations. First, the eigenfrequency spectra of finite periodic structures are compared with the location of stop-bands for their infinite counterparts for a hierarchy of four mathematical models....... In each case, special attention is paid to eigenfrequencies and eigenmodes of a single periodicity cell with appropriate boundary conditions. The influence of the amount of periodicity cells in a finite compound structure on its eigenfrequency spectrum is analyzed. Several features common...

  8. Periods and Nori motives

    CERN Document Server

    Huber, Annette

    2017-01-01

    This book casts the theory of periods of algebraic varieties in the natural setting of Madhav Nori’s abelian category of mixed motives. It develops Nori’s approach to mixed motives from scratch, thereby filling an important gap in the literature, and then explains the connection of mixed motives to periods, including a detailed account of the theory of period numbers in the sense of Kontsevich-Zagier and their structural properties. Period numbers are central to number theory and algebraic geometry, and also play an important role in other fields such as mathematical physics. There are long-standing conjectures about their transcendence properties, best understood in the language of cohomology of algebraic varieties or, more generally, motives. Readers of this book will discover that Nori’s unconditional construction of an abelian category of motives (over fields embeddable into the complex numbers) is particularly well suited for this purpose. Notably, Kontsevich's formal period algebra represents a to...

  9. Dunkerque-Falklands: Due eventi storico-politici attraverso l'analisi linguistica dei discorsi di Winston Churchill e Margaret Thatcher (Dunkirk-Falklands: Two Historical-Political Events through the Linguistic Analysis of the Speeches of Winston Churchill and Margaret Thatcher).

    Science.gov (United States)

    Arcaini, Giovanna

    1988-01-01

    The political speech is a unique kind of document that reflects the socio-historic climate of its time. Two historical events (Dunkirk and the Falkland Islands Crisis) and a principal protagonist from each are discussed, and the speeches of these two individuals are analyzed in order to find similarities and differences, and to find their basic…

  10. Co-design Events

    DEFF Research Database (Denmark)

    Brandt, Eva; Eriksen, Mette Agger

    2010-01-01

    One powerful co-design event is worth a thousand hours of individual work! Driving Innovation as a series of co-design events helps mobilize and involve all stakeholders to explore present everyday practices and to sketch new possible futures. But what makes a co-design event powerful? And why...... are series of events better than a sequence of deliverables and milestones in keeping innovation on track?...

  11. Event Modelling in CMS

    CERN Document Server

    Gunnellini, Paolo

    2017-01-01

    Latest tests of double parton scattering, underlying event tunes, minimum bias, and diffraction made by comparing CMS Run I and Run II data to the state-of-the-art theoretical predictions interfaced with up-to-date parton shower codes are presented. Studies to derive and to test the new CMS event tune obtained through jet kinematics in top quark pair events and global event variables are described.

  12. Conferences and Events

    International Development Research Centre (IDRC) Digital Library (Canada)

    André Lavoie

    2016-06-14

    Jun 14, 2016 ... Events include business meetings; corporate, branch or divisional management meetings; employee ... are responsible for demonstrating the highest standard of ethical conduct as outlined in the IDRC ... All other events such as social events, the Government of Canada Workplace Charitable. Campaign ...

  13. Traumatic events and children

    Science.gov (United States)

    ... for in your child and how to take care of your child after a traumatic event. Get professional help if your child is not recovering. Kinds of Traumatic Events Your child could experience a one-time traumatic event or a repeated trauma that happens over and over again. Examples of ...

  14. Poisoning due to pyrethroids.

    Science.gov (United States)

    Bradberry, Sally M; Cage, Sarah A; Proudfoot, Alex T; Vale, J Allister

    2005-01-01

    current') ensues which, if it is sufficiently large and/or long, lowers the action potential threshold and causes repetitive firing; this may be the mechanism causing paraesthesiae. At high pyrethroid concentrations, the sodium tail current may be sufficiently great to prevent further action potential generation and 'conduction block' ensues. Only low pyrethroid concentrations are necessary to modify sensory neurone function. Type II pyrethroids also decrease chloride currents through voltage-dependent chloride channels and this action probably contributes the most to the features of poisoning with type II pyrethroids. At relatively high concentrations, pyrethroids can also act on GABA-gated chloride channels, which may be responsible for the seizures seen with severe type II poisoning. Despite their extensive world-wide use, there are relatively few reports of human pyrethroid poisoning. Less than ten deaths have been reported from ingestion or following occupational exposure. Occupationally, the main route of pyrethroid absorption is through the skin. Inhalation is much less important but increases when pyrethroids are used in confined spaces. The main adverse effect of dermal exposure is paraesthesiae, presumably due to hyperactivity of cutaneous sensory nerve fibres. The face is affected most commonly and the paraesthesiae are exacerbated by sensory stimulation such as heat, sunlight, scratching, sweating or the application of water. Pyrethroid ingestion gives rise within minutes to a sore throat, nausea, vomiting and abdominal pain. There may be mouth ulceration, increased secretions and/or dysphagia. Systemic effects occur 4-48 hours after exposure. Dizziness, headache and fatigue are common, and palpitations, chest tightness and blurred vision less frequent. Coma and convulsions are the principal life-threatening features. Most patients recover within 6 days, although there were seven fatalities among 573 cases in one series and one among 48 cases in another

  15. Inguinal hernias associated with a single strenuous event.

    Science.gov (United States)

    Williamson, J S; Jones, H G; Radwan, R R; Rasheed, A

    2016-10-01

    There is debate regarding the role of physical activity and, in particular, a single strenuous event (SSE) in the development of inguinal hernia. This study aims to identify the incidence and associated features of hernias perceived to be due to a single strenuous event and to compare their features with published guidelines. All consecutive patients surgically treated for primary inguinal hernia at a single NHS trust between April 2010 and April 2011 were identified and contacted to participate in a questionnaire. Clinical details from operative records and case notes were compared with patients' responses to identify features of their presentation attributable to a single strenuous event according to previously published guidelines. Three hundred and thirty five eligible patients were contacted with a response rate of 292 (87 %). 41/292 (14 %) of patients reported an SSE associated with the onset of their hernia. Only 2 of 41 (5 %) patients reporting a hernia associated with SSE met published criteria for association of the hernia with SSE, and this represented less than 1 % of all patients treated for inguinal hernia at a single centre in a 1-year period. The relationship between physical activity and development of inguinal hernia is under debate; however, we find that inguinal hernia that can be attributed to SSE is a rare event, despite the fact that many patients present with acute symptoms. Updated guidelines for the assessment of 'cause' in industrial claims for the association of hernia with workplace activity are required.

  16. Mean-periodic functions

    Directory of Open Access Journals (Sweden)

    Carlos A. Berenstein

    1980-01-01

    Full Text Available We show that any mean-periodic function f can be represented in terms of exponential-polynomial solutions of the same convolution equation f satisfies, i.e., u∗f=0(μ∈E′(ℝn. This extends to n-variables the work of L. Schwartz on mean-periodicity and also extends L. Ehrenpreis' work on partial differential equations with constant coefficients to arbitrary convolutors. We also answer a number of open questions about mean-periodic functions of one variable. The basic ingredient is our work on interpolation by entire functions in one and several complex variables.

  17. 20 CFR 408.714 - When are reports due?

    Science.gov (United States)

    2010-04-01

    ... Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Reporting Requirements § 408.714 When are reports due? (a) A reportable event happens. You should report to us as soon as an event listed in § 408.708 happens. (b) We request a report. We may request a report...

  18. The Periodic Table CD.

    Science.gov (United States)

    Banks, Alton J.; Holmes, Jon L.

    1995-01-01

    Describes the characteristics of the digitized version of The Periodic Table Videodisc. Provides details about the organization of information and access to the data via Macintosh and Windows computers. (DDR)

  19. Setting the Periodic Table.

    Science.gov (United States)

    Saturnelli, Annette

    1985-01-01

    Examines problems resulting from different forms of the periodic table, indicating that New York State schools use a form reflecting the International Union of Pure and Applied Chemistry's 1984 recommendations. Other formats used and reasons for standardization are discussed. (DH)

  20. Flood basalts and extinction events

    Science.gov (United States)

    Stothers, Richard B.

    1993-01-01

    The largest known effusive eruptions during the Cenozoic and Mesozoic Eras, the voluminous flood basalts, have long been suspected as being associated with major extinctions of biotic species. Despite the possible errors attached to the dates in both time series of events, the significance level of the suspected correlation is found here to be 1 percent to 4 percent. Statistically, extinctions lag eruptions by a mean time interval that is indistinguishable from zero, being much less than the average residual derived from the correlation analysis. Oceanic flood basalts, however, must have had a different biological impact, which is still uncertain owing to the small number of known examples and differing physical factors. Although not all continental flood basalts can have produced major extinction events, the noncorrelating eruptions may have led to smaller marine extinction events that terminated at least some of the less catastrophically ending geologic stages. Consequently, the 26 Myr quasi-periodicity seen in major marine extinctions may be only a sampling effect, rather than a manifestation of underlying periodicity.

  1. Modelling the interaction between flooding events and economic growth

    Directory of Open Access Journals (Sweden)

    J. Grames

    2015-06-01

    Full Text Available Socio-hydrology describes the interaction between the socio-economy and water. Recent models analyze the interplay of community risk-coping culture, flooding damage and economic growth (Di Baldassarre et al., 2013; Viglione et al., 2014. These models descriptively explain the feedbacks between socio-economic development and natural disasters like floods. Contrary to these descriptive models, our approach develops an optimization model, where the intertemporal decision of an economic agent interacts with the hydrological system. In order to build this first economic growth model describing the interaction between the consumption and investment decisions of an economic agent and the occurrence of flooding events, we transform an existing descriptive stochastic model into an optimal deterministic model. The intermediate step is to formulate and simulate a descriptive deterministic model. We develop a periodic water function to approximate the former discrete stochastic time series of rainfall events. Due to the non-autonomous exogenous periodic rainfall function the long-term path of consumption and investment will be periodic.

  2. Pulmonary Complications due to Esophagectomy.

    Science.gov (United States)

    Shirinzadeh, Abulfazl; Talebi, Yashar

    2011-01-01

    Esophageal carcinoma is the scourge of human beings. Pulmonary complications in patients who have undergone operation are common (20-30% of cases) and there are no suitable tools and ways to predict these complications. During a period of 10 years, from March 1998 to February 2007, 200 patients (150 male and 50 female) underwent Esophagectomy due to esophageal carcinoma in thoracic surgery ward retrospectively. Complications include the length of hospitalization, mechanical ventilation, morbidity and mortality. Patients' risk factors include age, preoperative chemo-radiotherapy, stage of the disease and preoperative spirometry condition. WE GROUPED OUR PATIENTS INTO THREE CATEGORIES: Normal (FEV1 ≥ 80% predicted), mildly impaired (FEV1 65% to 79% predicted), more severely impaired (FEV1 atelectasia in 160 patients (80%). 24 patients needed chest-tube insertion. 20 patients (10%) developed ARDS. 14 patients (7%) developed chylothorax. 20 patients (10%) of patients died during their postoperative hospital stay. 30 patients (15%) required mechanical ventilation for greater than 48 hours. We reviewed a number of preoperative clinical variables to determine whether they contributed to postoperative pulmonary complications as well as other outcomes. In general, age, impaired pulmonary function especially in those patients with FEV1 less than 65% predicted was associated with prolonged hospital length of stay (LOS). In fact pulmonary complications rate after Esophagectomy are high and there was associated mortality and morbidity.

  3. ECOLOGIC DRIVERS AND POPULATION IMPACTS OF AVIAN TRICHOMONOSIS MORTALITY EVENTS IN BAND-TAILED PIGEONS (PATAGIOENAS FASCIATA) IN CALIFORNIA, USA.

    Science.gov (United States)

    Rogers, Krysta H; Girard, Yvette A; Koenig, Walter D; Johnson, Christine K

    2016-07-01

    :   Avian trichomonosis, a disease typically caused by the protozoan parasite Trichomonas gallinae , is a well recognized cause of death in many avian species. In California, US, trichomonosis has caused periodic epidemics in Pacific Coast Band-tailed Pigeons ( Patagioenas fasciata monilis). We summarize reported mortality events and investigate ecologic drivers and population impacts associated with epidemic mortality due to trichomonosis in Band-tailed Pigeons. Between 1945 and 2014, 59 mortality events involving Band-tailed Pigeons were reported in California with the number of reported events increasing over time. Estimated mortality for these events was variable, ranging between 10 and 10,000 pigeons. Events were most-frequently reported in Monterey (19%; 11/59) and San Luis Obispo (8%; 5/59) counties. Events often started in January (32%; 9/28) and February (50%; 14/28) and lasted 5-68 d. Impacts of mortality events on pigeon populations were indicated by Breeding Bird Survey and Christmas Bird Count abundance indices, which showed a decline in outbreak years compared to nonoutbreak years. Environmental conditions most associated with outbreak years included higher average temperatures between January and March, the period most associated with mortality events, and lower average precipitation in December just prior to mortality events. In Monterey County, events tended to occur in winters following higher acorn production of coast live oaks ( Quercus agrifolia ) in the fall. Weather and food abundance could be related to increased transmission or enhanced viability of Trichomonas spp. Although estimated mortality due to avian trichomonosis was highly variable across years, cumulative losses were substantial and likely to have a negative impact on population size.

  4. Extreme events in Faraday waves

    Science.gov (United States)

    Punzmann, Horst; Shats, Michael; Xia, Hua

    2014-05-01

    Observations of extreme wave events in the ocean are rare due to their low statistical probability. In the laboratory however, the evolution of extreme wave events can be studied in great detail with high spatial and temporal resolution. The reported surface wave experiments in the short wavelength gravity-capillary range aim to contribute to the understanding of some of the underlying mechanisms for rogue wave generation. In this talk, we report on extreme wave events in parametrically excited Faraday waves. Faraday waves appear if a fluid is accelerated (normal to the fluid surface) above a critical threshold. A variety of novel tools have been deployed to characterize the 2D surface elevation. The results presented show spatio-temporal and statistical data on the surface wave conditions leading up to extreme wave events. The peak in wave amplitude during such an event is shown to exceed six times the standard deviation of the average wave field with significantly increased statistical probability compared to the background wave field [1]. The experiments also show that parametrically excited waves can be viewed as assembles of oscillons [2] (or oscillating solitons) where modulation instability seems to play a crucial role in their formation. More detailed studies on the oscillon dynamics reveal that the onset of an increased probability of extreme wave events correlates with the increase in the oscillons mobility and merger [3]. Reference: 1. Xia H., Maimbourg T., Punzmann H., and Shats M., Oscillon dynamics and rogue wave generation in Faraday surface ripples, Physical Review Letters 109, 114502 (2012) 2. Shats M., Xia H., and Punzmann H., Parametrically excited water surface ripples as ensembles of oscillons, Physical Review Letters 108, 034502 (2012) 3. Shats M., Punzmann H., Xia H., Capillary rogue waves, Physical Review Letters, 104, 104503 (2010)

  5. Periodicity in magmatic systems

    Science.gov (United States)

    Caricchi, Luca

    2016-04-01

    Magmatic systems show periodicity in productivity, magma chemistry and dynamics of volcanic eruptions. The timescales over which such parameters change are highly variable and ranges between several tens of millions of years down to few hundredths of thousands years. While magmatic activity appears modulated at various frequencies, the lifetime of single volcanic systems, the duration of emplacement of single plutons, or the timespan over which a given volcanic region is active, appear to last for distinct but characteristic periods of time. Hundredths of thousands of years is a typical number for the range of zircon crystallisation ages in the products of large eruptions or for the lifetime of single plutons, while activity in volcanic regions or the duration of emplacement of crustal batholiths appears to last up to about 10 Ma. Several mechanisms such as variable magma productivity in the mantle, delamination, thermal and mechanical maturation of the crust have been proposed to modulate magmatic activity. All these processes indeed contribute to modulate the periodicity of magmatic activity, but because certain timescales are recurrent, some fundamental processes must play a fundamental role in regulating the "tempo" of magmatism. Are transitions of behaviour finally the product of major changes in mantle dynamics or is the crust the plays the pivotal role in modulating periodic variations observed in magmatic systems? In this contribution I will provide an overview of existing data on periodicity of magmatic systems and use thermal modelling to show that periodic variations of magma chemistry and the physical properties of magmas are an inexorable consequence of the evolution of the thermal budget of magmatic systems. I hope to trigger discussion and collaborations between experts of geodynamics and magmatism to establish relationships between periodicity, mantle and crustal processes.

  6. Analysis of rockburst and rockfall accidents in relation to class of stope support, regional support, energy of seismic events and mining layout

    CSIR Research Space (South Africa)

    Cichowicz, A

    1994-01-01

    Full Text Available This report discusses the assessment of safety risk and the analysis of Falls Of Ground (FOG) in mines due to seismic events and mining layout during the period of 1991-1992 on a single mine. The multivariate analysis was used to obtain a...

  7. Soundscapes, events, resistance

    Directory of Open Access Journals (Sweden)

    Andrea Mubi Brighenti

    2008-12-01

    Full Text Available Put it bluntly, a soundscape is the sonic counterpart, or component, of landscape. From such minimal assumption, some interesting consequences follow: just as landscape is far from being a simple stage-set upon which events take place, soundscape, too, is itself evental, i.e., it consists of events. Not only because its nature, far from being acoustics is always ‘psychoacoustics’, as Murray Schafer (1977/1994 first argued. Processes of environmental perception are of course there.

  8. Sustainability of a constructed wetland faced with a depredation event.

    Science.gov (United States)

    Maine, M A; Hadad, H R; Sánchez, G C; Mufarrege, M M; Di Luca, G A; Caffaratti, S E; Pedro, M C

    2013-10-15

    A free water surface constructed wetland (CW) designed for effluent treatment was dominated by the emergent macrophyte Typha domingensis reaching a cover of roughly 80% for 5 years. Highly efficient metal and nutrient removal was reported during this period. In June 2009, a population of approximately 30 capybaras (Hydrochoerus hydrochaeris) caused the complete depredation of the aerial parts of macrophytes. However, plant roots and rhizomes were not damaged. After depredation stopped, T. domingensis showed a luxuriant growth, reaching a cover of 60% in 30 days. The objective of this work was to evaluate the sustainability of the CW subjected to an extreme event. Removal efficiency of the system was compared during normal operation, during the depredation event and over the subsequent recovery period. The CW efficiently retained contaminants during all the periods studied. However, the best efficiencies were registered during the normal operation period. There were no significant differences between the performances of the CW over the last two periods, except for BOD. The mean removal percentages during normal operation/depredation event/recovery period, were: 84.9/73.2/74.7% Cr; 66.7/48.0/51.2% Ni; 97.2/91.0/89.4% Fe; 50.0/46.8/49.5% Zn; 81.0/84.0/80.4% NO3(-); 98.4/93.4/84.1% NO2(-); 73.9/28.2/53.2% BOD and 75.4/40.9/44.6% COD. SRP and TP presented low removal efficiencies. Despite the anoxic conditions, contaminants were not released from sediment, accumulating in fractions that proved to be stable faced with changes in the operating conditions of the CW. T. domingensis showed an excellent growth response, consequently the period without aerial parts lasted a few months and the CW could recover its normal operation. Plants continued retaining contaminants in their roots and the sediment increased its retention capacity, balancing the operating capacity of the system. This was probably due to the fact that the CW had reached its maturity, with a complete root

  9. EventThread: Visual Summarization and Stage Analysis of Event Sequence Data.

    Science.gov (United States)

    Guo, Shunan; Xu, Ke; Zhao, Rongwen; Gotz, David; Zha, Hongyuan; Cao, Nan

    2018-01-01

    Event sequence data such as electronic health records, a person's academic records, or car service records, are ordered series of events which have occurred over a period of time. Analyzing collections of event sequences can reveal common or semantically important sequential patterns. For example, event sequence analysis might reveal frequently used care plans for treating a disease, typical publishing patterns of professors, and the patterns of service that result in a well-maintained car. It is challenging, however, to visually explore large numbers of event sequences, or sequences with large numbers of event types. Existing methods focus on extracting explicitly matching patterns of events using statistical analysis to create stages of event progression over time. However, these methods fail to capture latent clusters of similar but not identical evolutions of event sequences. In this paper, we introduce a novel visualization system named EventThread which clusters event sequences into threads based on tensor analysis and visualizes the latent stage categories and evolution patterns by interactively grouping the threads by similarity into time-specific clusters. We demonstrate the effectiveness of EventThread through usage scenarios in three different application domains and via interviews with an expert user.

  10. Innovation, creative ideas to attend the challenges of the Central Laguna Verde for the period 2011-2015 due to new 100% of power; Innovacion, ideas creativas para atender los retos y desafios del periodo de la Central Laguna Verde en 2011-2015 por el nuevo 100% de potencia

    Energy Technology Data Exchange (ETDEWEB)

    Rivera C, A., E-mail: arr99999@cfe.gob.mx [Comision Federal de Electricidad, Central Nucleoelectrica Laguna Verde, Carretera Cardel-Nautla Km 42.5, Veracruz (Mexico)

    2011-11-15

    For the nuclear power plant of Laguna Verde (CLV) is an opportunity to present to the nuclear community in Mexico the improvement areas and challenges for the period 2011-2015, now that has been concluded the phase of starting tests of the CLV modernization, with an increment of power of 20% that represents a new generation of electrical power of 815 M We per hour in the 2 Units, with these new challenges the strategic planning 2011 at 2015 take relevance to give guide to the innovation, with new ideas of improvement to the processes, human resources and leadership, with the purpose of maintaining reliable all the equipment s and process systems by means of the use of strengths, opportunities, vulnerabilities and threats analysis, in order to make strategies that aid to generate competitive advantages for the production of electric power in Mexico, using privileged information that contain the database of the improvement systems, like are the programs of corrective action, of human acting, of external operational experience, of auto-evaluation and of benchmarking that is the referential comparison with other similar power stations. At present, in the general management of operation exist the training by coaching to grow in the formation of the half commands and line supervisors, reinforcing the wanted behaviors, the abilities of the technicians, and the orientation in deficient performances in the search of the operational excellence. (Author)

  11. Event-by-event fluctuations of mean transverse momentum in Au·Au ...

    Indian Academy of Sciences (India)

    Event-by-event fluctuations are considered to be one of the important tools to identify quark gluon plasma (QGP) phase transition. A first-order phase transition may lead to large fluctuations in energy density due to the formation of QGP droplets [1,2]. Second-order phase transitions may lead to divergence in the specific ...

  12. Adverse events associated with acupuncture: three multicentre randomized controlled trials of 1968 cases in China

    Directory of Open Access Journals (Sweden)

    Zheng Hui

    2011-03-01

    Full Text Available Abstract Background In order to evaluate the safety of acupuncture in China objectively, we investigated the adverse events associated with acupuncture based on three multicentre randomized controlled trials (RCTs to assess the safety of acupuncture, identifying the common types of acupuncture adverse events, and analysing the related risk factors for their occurrence. Methods This observational study included patients who received acupuncture from three multicentre RCTs respectively for migraine, functional dyspepsia and Bell's palsy. The 1968 patients and their acupuncturists documented adverse events associated with acupuncture after treatment. We collected data about adverse events due to acupuncture treatment from their case report forms. We analysed the incidence and details of the adverse effects, and studied the risk factors for acupuncture adverse events with non-conditional logistic regression analysis. Results Among the 1968 patients, 74 patients (3.76% suffered at least one adverse event throughout the treatment period. We did not observe the occurrence of serious adverse events. 73 patients with adverse events recovered within 2 weeks through effective treatment such as physiotherapy or self-treatment. A total of 3 patients withdrew because of adverse events. There were 9 types of adverse events related to acupuncture, including subcutaneous haematoma, bleeding, skin bruising and needle site pain. Subcutaneous haematoma and haemorrhage in the needling points were the most common adverse events. Age and gender were related to the occurrence of acupuncture adverse events. The older the patients were, the higher the risk of adverse events was. In addition, male patients had slightly higher risk of an adverse event than female patients. Conclusions Acupuncture is a safe therapy with low risk of adverse events in clinical practice. The risk factors for adverse events (AEs were related to the patients' gender and age and the local

  13. Periodic Table of Students.

    Science.gov (United States)

    Johnson, Mike

    1998-01-01

    Presents an exercise in which an eighth-grade science teacher decorated the classroom with a periodic table of students. Student photographs were arranged according to similarities into vertical columns. Students were each assigned an atomic number according to their placement in the table. The table is then used to teach students about…

  14. Hereditary periodic fever syndromes

    NARCIS (Netherlands)

    McDermott, MF; Frenkel, J

    Hereditary periodic fever syndromes are defined by recurrent attacks of generalised inflammation for which no infectious or auto-immune cause can be identified. For most of these disorders, the molecular basis has recently been elucidated. This has opened the prospect of novel therapeutic

  15. Sawtooth Period Scaling

    CERN Document Server

    Connor, J W; Hastie, R J; Zocco, A

    2012-01-01

    We discuss the role of neoclassical resistivity and local magnetic shear in the prediction of the sawtooth period in tokamaks. When collisional detrapping of electrons is considered the value of the safety factor on axis, $q(t,0)$, evolves on a new time scale, $\\tau_{*}=\\tau_{\\eta}\

  16. Features, Events, and Processes: Disruptive Events

    Energy Technology Data Exchange (ETDEWEB)

    J. King

    2004-03-31

    The primary purpose of this analysis is to evaluate seismic- and igneous-related features, events, and processes (FEPs). These FEPs represent areas of natural system processes that have the potential to produce disruptive events (DE) that could impact repository performance and are related to the geologic processes of tectonism, structural deformation, seismicity, and igneous activity. Collectively, they are referred to as the DE FEPs. This evaluation determines which of the DE FEPs are excluded from modeling used to support the total system performance assessment for license application (TSPA-LA). The evaluation is based on the data and results presented in supporting analysis reports, model reports, technical information, or corroborative documents that are cited in the individual FEP discussions in Section 6.2 of this analysis report.

  17. Un periodico come strumento per il giusto riconoscimento e la necessaria visibilità alle vittime / Un périodique comme instrument de reconnaissance due et de visibilité nécessaire aux victimes / A periodical as an instrument for the right recognition and the appropriate visibility to crime victims

    Directory of Open Access Journals (Sweden)

    Sette Raffaella

    2012-08-01

    Full Text Available The article retraces the history of Criminology, Victimology and Security Journal (Rivista di Criminologia, Vittimologia e Sicurezza, making an overview of the topics addressed in the publications.The author considers that this periodical could represent a piece of the big mosaic of the diffusion of the criminological culture where criminologists, victimologists, forensic doctors, psychiatrists, jurists, actors of the social control system, but also sociologists, psychologists, pedagogists and security experts find a space in order to think critically about crime and its various aspects taking different perspectives into consideration. It is clear that the only aim is to promote the development of this discipline.L’article retrace l’histoire de la Revue de Criminologie, Victimologie et Sécurité (Rivista di Criminologia, Vittimologia e Sicurezza, par un regard panoramique sur les sujets abordés dans les publications. L’auteur estime que cette revue peut représenter une tesselle de la grande mosaïque de la diffusion de la culture criminologique où des criminologues, des victimologues, des médecins légistes, des psychiatres, des juristes, des acteurs du système du contrôle social, mais aussi des sociologues, des psychologues, des pédagogues et des professionnels de la sécurité, trouvent un espace pour réfléchir de façon critique sur le phénomène criminel et ses diverses composantes en prenant en compte différentes perspectives, dans le seul but de promouvoir le développement de cette discipline.

  18. 75 FR 20294 - Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events...

    Science.gov (United States)

    2010-04-19

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events in the Fifth Coast Guard District AGENCY: Coast Guard, DHS... period of special local regulations for recurring marine events in the Fifth Coast Guard District. These...

  19. 76 FR 36308 - Special Local Regulation for Marine Events; Temporary Change of dates for Recurring Marine Events...

    Science.gov (United States)

    2011-06-22

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation for Marine Events; Temporary Change of dates for Recurring Marine Events in the Fifth Coast Guard District; Mill Creek, Hampton, VA... the enforcement period of one special local regulation for recurring marine events in the Fifth Coast...

  20. 76 FR 55558 - Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events...

    Science.gov (United States)

    2011-09-08

    ... SECURITY Coast Guard 33 CFR Part 100 RIN 1625-AA08 Special Local Regulation for Marine Events; Temporary Change of Dates for Recurring Marine Events in the Fifth Coast Guard District, John H. Kerr Reservoir... temporarily change the enforcement period of special local regulations for one recurring marine event in the...

  1. Features, Events, and Processes: Disruptive Events

    Energy Technology Data Exchange (ETDEWEB)

    P. Sanchez

    2004-11-08

    The purpose of this analysis report is to evaluate and document the inclusion or exclusion of the disruptive events features, events, and processes (FEPs) with respect to modeling used to support the total system performance assessment for license application (TSPA-LA). A screening decision, either ''Included'' or ''Excluded,'' is given for each FEP, along with the technical basis for screening decisions. This information is required by the U.S. Nuclear Regulatory Commission (NRC) at 10 CFR 63.114 (d), (e), and (f) [DIRS 156605]. The FEPs addressed in this report deal with both seismic and igneous disruptive events, such as fault displacements through the repository and an igneous intrusion into the repository. For included FEPs, this analysis summarizes the implementation of the FEP in TSPA-LA (i.e., how the FEP is included). For excluded FEPs, this analysis provides the technical basis for exclusion from TSPA-LA (i.e., why the FEP is excluded). Previous versions of this report were developed to support the total system performance assessments (TSPA) for various prior repository designs. This revision addresses the repository design for the license application (LA).

  2. Life Events and Personality Trait Change.

    Science.gov (United States)

    Bleidorn, Wiebke; Hopwood, Christopher J; Lucas, Richard E

    2018-02-01

    Theory and research have emphasized the impact of life events on personality trait change. In this article, we review prospective research on personality trait change in response to nine major life events in the broader domains of love and work. We expected to find that life events lead to personality trait change to the extent that they have a lasting influence on individuals' thoughts, feelings, and behavior. Moreover, we predicted that love-related life events such as marriage or parenthood would be more strongly related to changes in traits that emphasize affective content, whereas work-related life events would be more likely to lead to change in traits that reflect behavioral or cognitive content. The current state of research provided some evidence that life events can lead to changes in personality traits and that different life events may be differently related to specific trait domains. A more general conclusion emerging from this review is that the evidence for the nature, shape, and timing of personality trait change in response to life events is still preliminary. We discuss the implications of the results for theory and research and provide directions for future studies on life events and personality trait change. © 2016 Wiley Periodicals, Inc.

  3. Committed Sport Event Volunteers

    Science.gov (United States)

    Han, Keunsu; Quarterman, Jerome; Strigas, Ethan; Ha, Jaehyun; Lee, Seungbum

    2013-01-01

    The purpose of this study was to investigate the relationships among selected demographic characteristics (income, education and age), motivation and commitment of volunteers at a sporting event. Three-hundred and five questionnaires were collected from volunteers in a marathon event and analyzed using structural equation modeling (SEM). Based on…

  4. The ATLAS Event Builder

    CERN Document Server

    Vandelli, W; Battaglia, A; Beck, H P; Blair, R; Bogaerts, A; Bosman, M; Ciobotaru, M; Cranfield, R; Crone, G; Dawson, J; Dobinson, Robert W; Dobson, M; Dos Anjos, A; Drake, G; Ermoline, Y; Ferrari, R; Ferrer, M L; Francis, D; Gadomski, S; Gameiro, S; Gorini, B; Green, B; Haberichter, W; Haberli, C; Hauser, R; Hinkelbein, C; Hughes-Jones, R; Joos, M; Kieft, G; Klous, S; Korcyl, K; Kordas, K; Kugel, A; Leahu, L; Lehmann, G; Martin, B; Mapelli, L; Meessen, C; Meirosu, C; Misiejuk, A; Mornacchi, G; Müller, M; Nagasaka, Y; Negri, A; Pasqualucci, E; Pauly, T; Petersen, J; Pope, B; Schlereth, J L; Spiwoks, R; Stancu, S; Strong, J; Sushkov, S; Szymocha, T; Tremblet, L; Ünel, G; Vermeulen, J; Werner, P; Wheeler-Ellis, S; Wickens, F; Wiedenmann, W; Yu, M; Yasu, Y; Zhang, J; Zobernig, H; 2007 IEEE Nuclear Science Symposium and Medical Imaging Conference

    2008-01-01

    Event data from proton-proton collisions at the LHC will be selected by the ATLAS experiment in a three-level trigger system, which, at its first two trigger levels (LVL1+LVL2), reduces the initial bunch crossing rate of 40~MHz to $sim$3~kHz. At this rate, the Event Builder collects the data from the readout system PCs (ROSs) and provides fully assembled events to the Event Filter (EF). The EF is the third trigger level and its aim is to achieve a further rate reduction to $sim$200~Hz on the permanent storage. The Event Builder is based on a farm of O(100) PCs, interconnected via a Gigabit Ethernet to O(150) ROSs. These PCs run Linux and multi-threaded software applications implemented in C++. All the ROSs, and substantial fractions of the Event Builder and Event Filter PCs have been installed and commissioned. We report on performance tests on this initial system, which is capable of going beyond the required data rates and bandwidths for Event Building for the ATLAS experiment.

  5. The Agency of Event

    DEFF Research Database (Denmark)

    Nicholas, Paul; Tamke, Martin; Riiber, Jacob

    2014-01-01

    This paper explores the notion of agency within event-based models. We present an event-based modeling approach that links interdependent generative, analytic and decision making sub-models within a system of exchange. Two case study projects demonstrate the underlying modeling concepts and metho...

  6. Practices Surrounding Event Photos

    NARCIS (Netherlands)

    Vyas, Dhaval; Nijholt, Antinus; van der Veer, Gerrit C.; Kotzé, P.; Marsden, G.; Lindgaard, G.; Wesson, J.; Winckler, M.

    Sharing photos through mobile devices has a great potential for creating shared experiences of social events between co-located as well as remote participants. In order to design novel event sharing tools, we need to develop indepth understanding of current practices surrounding these so called

  7. Conferences and Events

    International Development Research Centre (IDRC) Digital Library (Canada)

    André Lavoie

    2016-01-18

    Jan 18, 2016 ... Evening meal events for Governors, held in connection with Board meetings, must not cost more per person than 2.625 times the applicable meal allowance. The Chair of the Board must authorize any exception to the provision of this paragraph. Overnight stays related to events (other than conferences and ...

  8. Caregiver anxiety due to interstage feeding concerns.

    Science.gov (United States)

    Stewart, Jamie; Dempster, Robert; Allen, Robin; Miller-Tate, Holly; Dickson, Gabrielle; Fichtner, Samantha; Principe, Alex J; Fonseca, Rachel; Nicholson, Lisa; Cua, Clifford L

    2015-01-01

    Improved weight gain during the interstage (IS) period has been shown to improve overall outcomes in patients with single ventricle physiology (SVP). This emphasis on nutrition may have untoward effects, such as increasing anxiety/stress levels in caregivers, who are already known to be at risk for increased anxiety/stress levels. The goal of this study was to evaluate anxiety/stress levels of caregivers as it pertains to feeding during the IS period and to determine if certain characteristics were associated with higher anxiety/stress scores. Caregivers of children with SVP who completed the IS period, defined as the time between the first and second cardiac surgeries, were recruited. Baseline demographics were obtained. Anxiety/stress levels were measured via eight questions using a 0- to 10-point scale. Correlations were performed between demographic variables and anxiety/stress level scores. Fifty-six surveys were completed (39 males, 27 females) on 43 children. Fourteen children required tube feeds during the IS period. There were significant correlations between anxiety/stress scores and caregiver's gender, caregiver's age, caregiver's level of education, percent of time a caregiver spent feeding the child, if caregivers were taking medications for anxiety, and if the child was seen in the emergency room during the IS period. There were no correlation of anxiety/stress scores with caregiver's race, child's underlying cardiac diagnosis, age of child, route of feeding during the IS period, birth order of the child or number of children in the family, relationship status, or distance from the hospital. In general, caregivers of children with SVP experience anxiety/stress during the IS period specifically due to feeding concerns. Certain intrinsic and extrinsic characteristics were associated with higher anxiety/stress levels. Future studies are needed to determine how to minimize anxiety/stress levels during this stressful time period. © 2015 Wiley Periodicals

  9. Satellite Anomalies Due to Environment

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These events range from minor operational problems to permanent spacecraft failures. Australia, Canada, Germany, India, Japan, United Kingdom, and the United States...

  10. Propagation of short-period gravity waves at high-latitudes during the MaCWAVE winter campaign

    Science.gov (United States)

    Nielsen, K.; Taylor, M. J.; Pautet, P.-D.; Fritts, D. C.; Mitchell, N.; Beldon, C.; Williams, B. P.; Singer, W.; Schmidlin, F. J.; Goldberg, R. A.

    2006-07-01

    As part of the MaCWAVE (Mountain and Convective Waves Ascending Vertically) winter campaign an all-sky monochromatic CCD imager has been used to investigate the properties of short-period mesospheric gravity waves at high northern latitudes. Sequential measurements of several nightglow emissions were made from Esrange, Sweden, during a limited period from 27-31 January 2003. Coincident wind measurements over the altitude range (~80-100 km) using two meteor radar systems located at Esrange and Andenes have been used to perform a novel investigation of the intrinsic properties of five distinct wave events observed during this period. Additional lidar and MSIS model temperature data have been used to investigate their nature (i.e. freely propagating or ducted). Four of these extensive wave events were found to be freely propagating with potential source regions to the north of Scandinavia. No evidence was found for strong orographic forcing by short-period waves in the airglow emission layers. The fifth event was most unusual exhibiting an extensive, but much smaller and variable wavelength pattern that appeared to be embedded in the background wind field. Coincident wind measurements indicated the presence of a strong shear suggesting this event was probably due to a large-scale Kelvin-Helmholtz instability.

  11. Propagation of short-period gravity waves at high-latitudes during the MaCWAVE winter campaign

    Directory of Open Access Journals (Sweden)

    K. Nielsen

    2006-07-01

    Full Text Available As part of the MaCWAVE (Mountain and Convective Waves Ascending Vertically winter campaign an all-sky monochromatic CCD imager has been used to investigate the properties of short-period mesospheric gravity waves at high northern latitudes. Sequential measurements of several nightglow emissions were made from Esrange, Sweden, during a limited period from 27–31 January 2003. Coincident wind measurements over the altitude range (~80–100 km using two meteor radar systems located at Esrange and Andenes have been used to perform a novel investigation of the intrinsic properties of five distinct wave events observed during this period. Additional lidar and MSIS model temperature data have been used to investigate their nature (i.e. freely propagating or ducted. Four of these extensive wave events were found to be freely propagating with potential source regions to the north of Scandinavia. No evidence was found for strong orographic forcing by short-period waves in the airglow emission layers. The fifth event was most unusual exhibiting an extensive, but much smaller and variable wavelength pattern that appeared to be embedded in the background wind field. Coincident wind measurements indicated the presence of a strong shear suggesting this event was probably due to a large-scale Kelvin-Helmholtz instability.

  12. Extreme and superextreme events in a loss-modulated CO2 laser: Nonlinear resonance route and precursors

    Science.gov (United States)

    Bonatto, Cristian; Endler, Antonio

    2017-07-01

    We investigate the occurrence of extreme and rare events, i.e., giant and rare light pulses, in a periodically modulated CO2 laser model. Due to nonlinear resonant processes, we show a scenario of interaction between chaotic bands of different orders, which may lead to the formation of extreme and rare events. We identify a crisis line in the modulation parameter space, and we show that, when the modulation amplitude increases, remaining in the vicinity of the crisis, some statistical properties of the laser pulses, such as the average and dispersion of amplitudes, do not change much, whereas the amplitude of extreme events grows enormously, giving rise to extreme events with much larger deviations than usually reported, with a significant probability of occurrence, i.e., with a long-tailed non-Gaussian distribution. We identify recurrent regular patterns, i.e., precursors, that anticipate the emergence of extreme and rare events, and we associate these regular patterns with unstable periodic orbits embedded in a chaotic attractor. We show that the precursors may or may not lead to the emergence of extreme events. Thus, we compute the probability of success or failure (false alarm) in the prediction of the extreme events, once a precursor is identified in the deterministic time series. We show that this probability depends on the accuracy with which the precursor is identified in the laser intensity time series.

  13. Analysis of geohazards events along Swiss roads from autumn 2011 to present

    Science.gov (United States)

    Voumard, Jérémie; Jaboyedoff, Michel; Derron, Marc-Henri

    2014-05-01

    In Switzerland, roads and railways are threatened throughout the year by several natural hazards. Some of these events reach transport infrastructure many time per year leading to the closing of transportation corridors, loss of access, deviation travels and sometimes infrastructures damages and loss of human lives (3 fatalities during the period considered). The aim of this inventory of events is to investigate the number of natural events affecting roads and railways in Switzerland since autumn 2011 until now. Natural hazards affecting roads and railway can be classified in five categories: rockfalls, landslides, debris flows, snow avalanches and floods. They potentially cause several important direct damages on transportation infrastructure (roads, railway), vehicles (slightly or very damaged) or human life (slightly or seriously injured person, death). These direct damages can be easily evaluated from press articles or from Swiss police press releases. Indirect damages such as deviation cost are not taken into account in this work. During the two a half last years, about 50 events affecting the Swiss roads and Swiss railways infrastructures were inventoried. The proportion of events due to rockfalls is 45%, to landslides 25%, to debris flows 15%, to snow avalanches 10% and to floods 5%. During this period, three fatalities and two persons were injured while 23 vehicles (car, trains and coach) and 24 roads and railways were damaged. We can see that floods occur mainly on the Swiss Plateau whereas rockfalls, debris flow, snow avalanches and landslides are mostly located in the Alpine area. Most of events occur on secondary mountain roads and railways. The events are well distributed on the whole Alpine area except for the Gotthard hotspot, where an important European North-South motorway (hit in 2003 with two fatalities) and railway (hit three times in 2012 with one fatalities) are more frequently affected. According to the observed events in border regions of

  14. Forbush Decrease events in Lunar Radiation Environment observed by the LRO/CRaTER

    Science.gov (United States)

    Sohn, J.; Oh, S.; Yi, Y.; Kim, E.; Lee, J.; Spence, H. E.

    2012-12-01

    The Lunar Reconnaissance Orbiter (LRO) launched on June 16, 2009 has six experiments including of the Cosmic Ray Telescope for the Effects of Radiation (CRaTER) onboard. The CRaTER instrument characterizes the radiation environment to be experienced by humans during future lunar missions. The CRaTER instrument measures the effects of ionizing energy loss in matter specifically in silicon solid-state detectors due to penetrating solar energetic protons (SEP) and galactic cosmic rays (GCR) after interactions with tissue-equivalent plastic (TEP), a synthetic analog of human tissue. The CRaTER instrument houses a compact and highly precise microdosimeter. It measures dose rates below one micro-Rad/sec in lunar radiation environment. Forbush decrease (FD) event is the sudden decrease of galactic cosmic ray (GCR) flux. The FD event is considered to be caused by exclusion of GCR due to intense interplanetary magnetic field (IMF) structures of interplanetary shock (IP) sheath region and/or the interplanetary coronal mass ejection (CME) following the IP shocks as a shock driver. We use the data of cosmic ray flux and dose rates observed by the CRaTER instrument. We also use the CME list of STEREO SECCHI inner, outer coronagraph and the IMF (Interplanetary CME) data of the ACE/MAG instrument. We examine the origins and the characteristics of the FD-like events in lunar radiation environment. We also compare these events with the FD events on the Earth. We find that whenever the FD events are recorded at ground Neutron Monitor stations, the FD-like events also occur on the lunar environments. The flux variation amplitude of FD-like events on the Moon is approximately two times larger than that of FD events on the Earth. We compare time profiles of GCR flux with of the dose rate of FD-like events in the lunar environment. We figure out that the distinct FD-like events correspond to dose rate events in the CRaTER on lunar environment during the event period.

  15. 40 CFR 51.930 - Mitigation of Exceptional Events.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Mitigation of Exceptional Events. 51... Mitigation of Exceptional Events. (a) A State requesting to exclude air quality data due to exceptional events must take appropriate and reasonable actions to protect public health from exceedances or...

  16. Extreme events in time-delayed nonlinear optics.

    Science.gov (United States)

    Dal Bosco, Andreas Karsaklian; Wolfersberger, Delphine; Sciamanna, Marc

    2013-03-01

    We report experimentally on extreme events in the pulsating dynamics of an optical time-delayed system, i.e., a diode laser subject to a phase-conjugate feedback. We study the effect of the feedback strength on extreme events' properties. We show a transition to non-Gaussian statistics of the pulse intensity and an increased number of extreme events as the mirror reflectivity increases. The extreme event pulse is anticipated and followed by smaller pulses with time-delay periodicity.

  17. Stability of Periodic Locomotion in Potential Flow

    CERN Document Server

    Jing, Fangxu

    2013-01-01

    Most aquatic vertebrates swim by lateral flapping of their bodies and caudal fins. While much effort has been devoted to understanding the flapping kinematics and its influence on the swimming efficiency, little is known about the stability (or lack of) of periodic swimming. In this paper, we examine the stability of periodic locomotion due to sideways flapping in unbounded potential flow. It is believed that stability limits maneuverability and body designs/flapping motions that are adapted for stable swimming are not suitable for high maneuverability and vice versa. Here, we consider a simplified model where the swimmer is a planar elliptic body undergoing prescribed periodic heaving and pitching. We show that periodic locomotion can be achieved due to the resulting hydrodynamic forces, and its value depends on several parameters including the aspect ratio of the body, the amplitudes and phases of the prescribed flapping. We obtain closed-form solutions for the locomotion and efficiency for small flapping a...

  18. Temperature distribution of a simplified rotor due to a uniform heat source

    Science.gov (United States)

    Welzenbach, Sarah; Fischer, Tim; Meier, Felix; Werner, Ewald; kyzy, Sonun Ulan; Munz, Oliver

    2017-11-01

    In gas turbines, high combustion efficiency as well as operational safety are required. Thus, labyrinth seal systems with honeycomb liners are commonly used. In the case of rubbing events in the seal system, the components can be damaged due to cyclic thermal and mechanical loads. Temperature differences occurring at labyrinth seal fins during rubbing events can be determined by considering a single heat source acting periodically on the surface of a rotating cylinder. Existing literature analysing the temperature distribution on rotating cylindrical bodies due to a stationary heat source is reviewed. The temperature distribution on the circumference of a simplified labyrinth seal fin is calculated using an available and easy to implement analytical approach. A finite element model of the simplified labyrinth seal fin is created and the numerical results are compared to the analytical results. The temperature distributions calculated by the analytical and the numerical approaches coincide for low sliding velocities, while there are discrepancies of the calculated maximum temperatures for higher sliding velocities. The use of the analytical approach allows the conservative estimation of the maximum temperatures arising in labyrinth seal fins during rubbing events. At the same time, high calculation costs can be avoided.

  19. Faraday rotation effect in periodic graphene structure

    Science.gov (United States)

    Liu, Daqing; Zhang, Shengli; Ma, Ning; Li, Xinghua

    2012-07-01

    We report the magneto-optical (MO) rotation effect in a periodic graphene-sheet structure. Due to the masslessness of carriers in graphene, the magnetic response is very sensitive and the magneto-optical rotation effect is therefore significant. We predict that the Verdet constant of the periodic graphene-sheet structure is roughly 10-100 times that of rare-earth-doped magneto-optical glass in the infrared region.

  20. Faraday rotation effect in periodic graphene structure

    OpenAIRE

    Liu, Daqing; Zhang, Shengli; Ma, Ning; Li, Xinghua

    2012-01-01

    We report the magneto-optical rotation effect in a periodic graphene-sheet structure. Due to the masslessness of carriers in graphene, the magnetic response is very sensitive and the magneto-optical rotation effect is therefore significant. We predict that the Verdet constant of the periodic graphene-sheet structure is roughly 10-100 times that of rare-earth-doped magneto-optical glass in the infrared region.

  1. Special Features In Turbulent Mixing. Comparison between Periodic and Non Periodic Case

    Directory of Open Access Journals (Sweden)

    Mihai Costescu

    2006-12-01

    Full Text Available After hundreds of years of stability study, the problems of flow kinematics are far from complete solving. A modern theory appears in this field: the mixing theory. Its mathematical methods and techniques developed the significant relation between turbulence and chaos. The turbulence is an important feature of dynamic systems with few freedom degrees, the so-called far from equilibrium systems. These are widespread between the models of excitable media.Studying a mixing for a flow implies the analysis of successive stretching and folding phenomena for its particles, the influence of parameters and initial conditions. In the previous works, the study of the 3D non-periodic models exhibited a quite complicated behavior, involving some significant events - the so-called rare events. The variation of parameters had a great influence on the length and surface deformations. The 2D (periodic case is simpler, but significant events can also issue for irrational values of the length and surface versors, as was the situation in 3D case.The comparison between 2D and 3D case revealed interesting properties; therefore a modified 2D (periodic model is tested. The numerical simulations were realized in MapleVI, for searching special mathematical events. Continuing this work both from analytical and numeric standpoint would relieve useful properties for the turbulent mixing. A proximal target is to test some special functions for the periodic model, and to study the behavior of the structures realized by the model.

  2. Boosting Event Building Performance using Infiniband FDR for CMS Upgrade

    CERN Document Server

    Bawej, Tomasz Adrian; Branson, James; Chaze, Olivier; Cittolin, Sergio; Darlea, Georgiana Lavinia; Deldicque, Christian; Dobson, Marc; Dupont, Aymeric; Erhan, Samim; Forrest, Andrew Kevin; Gigi, Dominique; Glege, Frank; Gomez Ceballos, Guillelmo; Gomez-Reino Garrido, Robert; Hegeman, Jeroen Guido; Holzner, Andre Georg; Masetti, Lorenzo; Meijers, Franciscus; Meschi, Emilio; Mommsen, Remigius; Morovic, Srecko; Nunez Barranco Fernandez, Carlos; Vivian O'Dell; Orsini, Luciano; Paus, Christoph Maria Ernst; Petrucci, Andrea; Pieri, Marco; Racz, Attila; Sakulin, Hannes; Schwick, Christoph; Stieger, Benjamin Bastian; Sumorok, Konstanty; Veverka, Jan; Zejdl, Petr

    2014-01-01

    As part of the CMS upgrade during CERN long shutdown period (LS1), the CMS data acquisition system is incorporating Infiniband FDR technology to boost event building performance for operation from 2015 onwards. Infiniband promises to provide substantial increase in data transmission speeds compared to the older 1GE network used during the 2009-2013 LHC run. Several options exist to end user developers when choosing a foundation for software upgrades, including the uDAPL (DAT Collaborative) and Infiniband verbs libraries (OFED). Due to advances in technology, the CMS data acquisition system will be able to achieve the required throughput of 100 kHz with increased event sizes while downsizing the number of nodes by using a combination of 10GE, 40GE and 56 GB Infiniband FDR. This paper presents the analysis and results of a comparison between GE and Infiniband solutions as well as a look at how they integrate into an event building architecture, while preserving the scalability, efficiency and deterministic late...

  3. Periodic Mesoporous Organosilica Nanorice

    Directory of Open Access Journals (Sweden)

    Mohanty Paritosh

    2008-01-01

    Full Text Available Abstract A periodic mesoporous organosilica (PMO with nanorice morphology was successfully synthesized by a template assisted sol–gel method using a chain-type precursor. The PMO is composed of D and T sites in the ratio 1:2. The obtained mesoporous nanorice has a surface area of 753 m2 g−1, one-dimensional channels, and a narrow pore size distribution centered at 4.3 nm. The nanorice particles have a length of ca. 600 nm and width of ca. 200 nm.

  4. The postanesthetic period. Complications.

    Science.gov (United States)

    Malamed, S F

    1987-01-01

    Postanesthetic complications can occur even in the best of circumstances. Proper preparation of the staff, aggressive monitoring of the recovering patient, and early recognition and management of the complications are essential if the outcome is to be successful. In reviewing postanesthetic complications, two factors are present in the overwhelming majority of situations--hypoxia and hypercarbia--often the direct result of inadequate monitoring during the postanesthetic period. The anesthetic procedure is not over once the anesthetic agents are discontinued. The skillful anesthetist is aware of the possibilities of postoperative complications and prevents problems by employing enhanced monitoring techniques during the recovery phase.

  5. Periods of Hecke characters

    CERN Document Server

    Schappacher, Norbert

    1988-01-01

    The starting point of this Lecture Notes volume is Deligne's theorem about absolute Hodge cycles on abelian varieties. Its applications to the theory of motives with complex multiplication are systematically reviewed. In particular, algebraic relations between values of the gamma function, the so-called formula of Chowla and Selberg and its generalization and Shimura's monomial relations among periods of CM abelian varieties are all presented in a unified way, namely as the analytic reflections of arithmetic identities beetween Hecke characters, with gamma values corresponding to Jacobi sums. The last chapter contains a special case in which Deligne's theorem does not apply.

  6. Shallow repeating seismic events under an alpine glacier at Mount Rainier, Washington, USA

    Science.gov (United States)

    Thelen, Weston A.; Allstadt, Kate E.; De Angelis, Silvio; Malone, Stephen D.; Moran, Seth C.; Vidale, John

    2013-01-01

    We observed several swarms of repeating low-frequency (1–5 Hz) seismic events during a 3 week period in May–June 2010, near the summit of Mount Rainier, Washington, USA, that likely were a result of stick–slip motion at the base of alpine glaciers. The dominant set of repeating events ('multiplets') featured >4000 individual events and did not exhibit daytime variations in recurrence interval or amplitude. Volcanoes and glaciers around the world are known to produce seismic signals with great variability in both frequency content and size. The low-frequency character and periodic recurrence of the Mount Rainier multiplets mimic long-period seismicity often seen at volcanoes, particularly during periods of unrest. However, their near-surface location, lack of common spectral peaks across the recording network, rapid attenuation of amplitudes with distance, and temporal correlation with weather systems all indicate that ice-related source mechanisms are the most likely explanation. We interpret the low-frequency character of these multiplets to be the result of trapping of seismic energy under glacial ice as it propagates through the highly heterogeneous and attenuating volcanic material. The Mount Rainier multiplet sequences underscore the difficulties in differentiating low-frequency signals due to glacial processes from those caused by volcanic processes on glacier-clad volcanoes.

  7. Orthokeratology vs. spectacles: adverse events and discontinuations.

    Science.gov (United States)

    Santodomingo-Rubido, Jacinto; Villa-Collar, César; Gilmartin, Bernard; Gutiérrez-Ortega, Ramón

    2012-08-01

    To assess the relative clinical success of orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) in children in terms of incidences of adverse events and discontinuations over a 2-year period. Sixty-one subjects 6 to 12 years of age with myopia of - 0.75 to - 4.00DS and astigmatism ≤1.00DC were prospectively allocated OK or SV correction. Subjects were followed at 6-month intervals and advised to report to the clinic immediately should adverse events occur. Adverse events were categorized into serious, significant, and non-significant. Discontinuation was defined as cessation of lens wear for the remainder of the study. Thirty-one children were corrected with OK and 30 with SV. A higher incidence of adverse events was found with OK compared with SV (p < 0.001). Nine OK subjects experienced 16 adverse events (7 significant and 9 non-significant). No adverse events were found in the SV group. Most adverse events were found between 6 and 12 months of lens wear, with 11 solely attributable to OK wear. Significantly more discontinuations were found with SV in comparison with OK (p < 0.05). The relatively low incidence of adverse events and discontinuations with OK is conducive for the correction of myopia in children with OK contact lenses.

  8. RAS Initiative - Events

    Science.gov (United States)

    The NCI RAS Initiative has organized multiple events with outside experts to discuss how the latest scientific and technological breakthroughs can be applied to discover vulnerabilities in RAS-driven cancers.

  9. News and Events

    Science.gov (United States)

    The latest news from the Office of Cancer Nanotechnology Research and the Alliance, as well as upcoming and past events attended by the Office of Cancer Nanotechnology Research staff, and relevant upcoming scientific meetings.

  10. "Universe" event at AIMS

    Science.gov (United States)

    2008-06-01

    Report of event of 11 May 2008 held at the African Institute of Mathematical Sciences (Muizenberg, Cape), with speakers Michael Griffin (Administrator of NASA), Stephen Hawking (Cambridge), David Gross (Kavli Institute, Santa Barbara) and George Smoot (Berkeley).

  11. Analysis of extreme events

    CSIR Research Space (South Africa)

    Khuluse, S

    2009-04-01

    Full Text Available ) determination of the distribution of the damage and (iii) preparation of products that enable prediction of future risk events. The methodology provided by extreme value theory can also be a powerful tool in risk analysis...

  12. Event visualization in ATLAS

    Science.gov (United States)

    Bianchi, R. M.; Boudreau, J.; Konstantinidis, N.; Martyniuk, A. C.; Moyse, E.; Thomas, J.; Waugh, B. M.; Yallup, D. P.; ATLAS Collaboration

    2017-10-01

    At the beginning, HEP experiments made use of photographical images both to record and store experimental data and to illustrate their findings. Then the experiments evolved and needed to find ways to visualize their data. With the availability of computer graphics, software packages to display event data and the detector geometry started to be developed. Here, an overview of the usage of event display tools in HEP is presented. Then the case of the ATLAS experiment is considered in more detail and two widely used event display packages are presented, Atlantis and VP1, focusing on the software technologies they employ, as well as their strengths, differences and their usage in the experiment: from physics analysis to detector development, and from online monitoring to outreach and communication. Towards the end, the other ATLAS visualization tools will be briefly presented as well. Future development plans and improvements in the ATLAS event display packages will also be discussed.

  13. Event visualization in ATLAS

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00211497; The ATLAS collaboration; Boudreau, Joseph; Konstantinidis, Nikolaos; Martyniuk, Alex; Moyse, Edward; Thomas, Juergen; Waugh, Ben; Yallup, David

    2017-01-01

    At the beginning, HEP experiments made use of photographical images both to record and store experimental data and to illustrate their findings. Then the experiments evolved and needed to find ways to visualize their data. With the availability of computer graphics, software packages to display event data and the detector geometry started to be developed. Here, an overview of the usage of event display tools in HEP is presented. Then the case of the ATLAS experiment is considered in more detail and two widely used event display packages are presented, Atlantis and VP1, focusing on the software technologies they employ, as well as their strengths, differences and their usage in the experiment: from physics analysis to detector development, and from online monitoring to outreach and communication. Towards the end, the other ATLAS visualization tools will be briefly presented as well. Future development plans and improvements in the ATLAS event display packages will also be discussed.

  14. CCG - News & Events

    Science.gov (United States)

    NCI's Center for Cancer Genomics (CCG) has been widely recognized for its research efforts to facilitiate advances in cancer genomic research and improve patient outcomes. Find the latest news about and events featuring CCG.

  15. Discrete Event Simulation

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 18; Issue 1. Discrete Event Simulation. Matthew Jacob ... Keywords. Simulation; modelling; computer programming. Author Affiliations. Matthew Jacob1. Department of Computer Science and Automation, Indian Institute of Science, Bangalore 560 012.

  16. Gargamelle: neutral current event

    CERN Multimedia

    1973-01-01

    This event shows real tracks of particles from the 1200 litre Gargamelle bubble chamber that ran on the PS from 1970 to 1976 and on the SPS from 1976 to 1979. In this image a neutrino passes close to a nucleon and reemerges as a neutrino. Such events are called neutral curent, as they are mediated by the Z0 boson which has no electric charge.

  17. QCD (&) event generators

    Energy Technology Data Exchange (ETDEWEB)

    Skands, Peter Z.; /Fermilab

    2005-07-01

    Recent developments in QCD phenomenology have spurred on several improved approaches to Monte Carlo event generation, relative to the post-LEP state of the art. In this brief review, the emphasis is placed on approaches for (1) consistently merging fixed-order matrix element calculations with parton shower descriptions of QCD radiation, (2) improving the parton shower algorithms themselves, and (3) improving the description of the underlying event in hadron collisions.

  18. Seismic event classification system

    Science.gov (United States)

    Dowla, Farid U.; Jarpe, Stephen P.; Maurer, William

    1994-01-01

    In the computer interpretation of seismic data, the critical first step is to identify the general class of an unknown event. For example, the classification might be: teleseismic, regional, local, vehicular, or noise. Self-organizing neural networks (SONNs) can be used for classifying such events. Both Kohonen and Adaptive Resonance Theory (ART) SONNs are useful for this purpose. Given the detection of a seismic event and the corresponding signal, computation is made of: the time-frequency distribution, its binary representation, and finally a shift-invariant representation, which is the magnitude of the two-dimensional Fourier transform (2-D FFT) of the binary time-frequency distribution. This pre-processed input is fed into the SONNs. These neural networks are able to group events that look similar. The ART SONN has an advantage in classifying the event because the types of cluster groups do not need to be pre-defined. The results from the SONNs together with an expert seismologist's classification are then used to derive event classification probabilities.

  19. Predictors of post-event rumination related to social anxiety.

    Science.gov (United States)

    Kocovski, Nancy L; Rector, Neil A

    2007-01-01

    Post-event processing is the cognitive rumination that follows social events in cognitive models of social anxiety. The aim of this study was to examine factors that may predict the extent to which individuals engage in post-event processing. Anxious rumination, social anxiety, anxiety sensitivity and post-event processing related to a recent anxiety-provoking social event were assessed in a college student sample (n = 439). Social anxiety and anxious rumination, but not anxiety sensitivity, significantly predicted the extent to which the participants engaged in post-event processing related to an anxiety-provoking social event. Factors that appear to impact on the post-event period include the nature of the social situation and the ethnicity of the participant. It appears that both general rumination over anxious symptoms, and specific rumination related to social events are relevant for cognitive models of social anxiety.

  20. Simulation of land use evolution by discrete events method: Application to “la chaîne des puys” from XV to XVIII Century

    Directory of Open Access Journals (Sweden)

    Y. Michelin

    1998-01-01

    Full Text Available By using a discrete event method, simulation of land use evolution has been applied to a landscape model of “la ChaÎne des Puys” (French Massif Central during along period (XV–XVIII centuries. The indications concerning the evolution of land use are in conformity with the observation of actual situations but the dynamic changes are faster than in actual facts. In spite of limitations due to necessary simplifications, it is now established that the discrete event method is efficient to simulate land use evolution during a long period. The model is immediately able to describe actual dynamics and to show sensitive variables with their critical values. Although oversimplified, it shows how far factors such as level of crops production and taxation can influence land use and landscape changes with a more or less lengthy period. In the future, the model should be bettered by introducing other determined and/or stochastic events.

  1. Hypokalemic periodic paralysis: Three rare secondary causes

    Directory of Open Access Journals (Sweden)

    Prasanna Eswaradass Venkatesan

    2015-01-01

    Full Text Available Periodic paralysis is a rare neuromuscular disorder, related to a defect in muscle ion channels, characterized by episodes of painless muscle weakness, which may be precipitated by heavy exercise, fasting, or high-carbohydrate meals. Hypokalemic periodic paralysis may be familial (primary or secondary. Here, we report three cases of secondary causes of hypokalemic periodic paralysis. On evaluation, case 1 had distal renal tubular acidosis (RTA due to Sjogren′s syndrome, case 2 had drug induced proximal RTA (Fanconi′s syndrome and case 3 had thyrotoxicosis. Clinician must be aware of causes of secondary PP as recognition and diagnosis can completely prevent further attacks of periodic paralysis. Each of the above case is rare, but completely treatable if diagnosed. Low dose steroids with bicarbonate replacement in case 1, stopping tenofovir in case 2 and carbimazole therapy in case 3 prevented further attacks of periodic paralysis and cardiopulmonary complications.

  2. Extreme Events: The Indian Experience

    Science.gov (United States)

    Murty, K. S.

    2008-05-01

    The geographical situation of India is such that it experiences varied types of climate in different parts of the country and invariably the natural events, extreme and normal, would affect such areas that are prone to them. Cyclones hit the eastern coast, while floods affect mostly northern India, while earthquakes hit any part of the country, particuarly when itbecame evident after the 1967 earthquake of Koyna that the peninsular part toois prone to seismic events. The National Commission on Floods estimated that nearly 40 millionn hectares of land is prone to flooding, which could rise to60 million soon. The cropped area thus affected annually is about 10 millionhectares. On an average 1500 lives are lost during floods annually, while the damage to property could run into billions of dollars. The total loss on account of floods damage to crops is estimated at about Rs 53,000 crores(crore= 100 lakhs), during the period 1953-1998. The other extreme natural event is drought which affects large parts of the country, except the northeast. Both floods and droughts can hit different parts of the country during the same period. The 2001 earthquake that hit Gujarat is perhaps the severest and studies on that event are still in progress. The 2004 tsunami which hit large parts of southeast Asia did not spare India. Its southern coast was battered and many lives were lost. In fact some geogrphic landmarks were lost, while some of the cities have suffered a shift in their position. It was estimated that about 1.2 billion dollars were required ro meet the rehabilitation and relief measures. The seismic zone map of India thus had to be revised more often than before. Apart from these, extreme rainfall has also caused floods in urban areas as in Mumbai in 2005, but this was mostly because of lack of proper drainage system and the existing system proved ineffective. Human hand in such cases is evident. There are systems working to forecast floods, cyclones, and droughts, though

  3. Statistical analysis of solar proton events

    Directory of Open Access Journals (Sweden)

    V. Kurt

    2004-06-01

    Full Text Available A new catalogue of 253 solar proton events (SPEs with energy >10MeV and peak intensity >10 protons/cm2.s.sr (pfu at the Earth's orbit for three complete 11-year solar cycles (1970-2002 is given. A statistical analysis of this data set of SPEs and their associated flares that occurred during this time period is presented. It is outlined that 231 of these proton events are flare related and only 22 of them are not associated with Ha flares. It is also noteworthy that 42 of these events are registered as Ground Level Enhancements (GLEs in neutron monitors. The longitudinal distribution of the associated flares shows that a great number of these events are connected with west flares. This analysis enables one to understand the long-term dependence of the SPEs and the related flare characteristics on the solar cycle which are useful for space weather prediction.

  4. EERE Showcase Event (Solar Decathlon 2015)

    Energy Technology Data Exchange (ETDEWEB)

    Tolles, Eric [Orange County Great Park Corporation, Irvine, CA (United States)

    2016-04-15

    The goal of the Orange County Great Park Corporation (Great Park) is to successfully host the U.S. Department of Energy Solar Decathlon 2015. In furtherance of that goal, tasks to be performed within the current reporting period include the following: Task 1.0 Arrange Site Team Visits for January 2015 The Great Park arranged appropriate meeting space for the site team visits over a three-day period, January 8, 2015 through January 10, 2015. Instead of a meeting in Hanger 244, the DOE requested a different meeting space. The working team met in the Operations offices on January 8th. The student teams were welcomed at the City of Irvine’s Lakeview Senior Center on January 9th, and came back on January 10th for breakout sessions. Task 2.0 Outreach Activities The following outreach activities related to the U.S. Department of Energy Solar Decathlon 2015 occurred during and prior to the event: • Promoted the return of the Solar Decathlon 2015 on the City’s website. (cityofirvine.org) • Promoted the return of the Solar Decathlon 2015 through the City’s and Great Park’s social media channels, including Facebook and Twitter. (facebook.com/cityofirvine, facebook.com/orangecountygreatpark, twitter.com/City_of_Irvine, twitter.com/ocgreatpark) • Promoted the return of the Solar Decathlon 2015 and student visit through a City Council Announcement. • Worked to set-up meetings between the U.S. Department of Energy team and potential donors/key stakeholders in Irvine. • Began ICTV filming and coverage of the Solar Decathlon 2015 teams. This includes student team interviews, interview with Richard King and b-roll footage. • Facilitated an interview with Sarah Farrar and the Orange County Register during the recent student visit in January • Information in May was provided to Irvine Unified School District and Tustin Unified School District promoting the three Education Days that the DOE will host during the event. More DOE information is due in August, which

  5. Increasing erosion risk due to the climate change in a small forested catchment of Sopron Hills

    Science.gov (United States)

    Csáfordi, Péter; Gálos, Borbála; Kalicz, Péter; Gribovszki, Zoltán

    2013-04-01

    According to the climate predictions, hydro-meteorological conditions expected to change in the future, leading to the alteration of erosion dynamics. Based on regional climate projections, climatic extremes may become more frequent for the end of the 21st century. Intensive rainfall events may increase soil loss on the sloping areas resulting in potentially significant on-site and off-site ecological and economical damages as well. The aim of our study was to determine the erosion impact of single rainfall events in a selected hydrologic year (2008-2009) for a 0.6 km2 forested catchment in the Sopron Hills using the erosion model EROSION-3D. Furthermore the probability of intense and erosive rainfall events has been analyzed for the time period 2071-2100, applying the regional climate model REMO (developed at the Max Planck Institute for Meteorology, Hamburg). Those rainfall events, where maximal 1-hour precipitation exceeded the 90th percentile value (6 mm), have been classified as intensive rainfall events. The erosion-accumulation maps based on the EROSION-3D model demonstrate well, that higher 1-hour precipitation may cause higher rate of soil loss if every other influencing factor are fixed (e.g. land cover, relief and runoff conditions) and the extension of erosion threatened area increases. Simulation results of the regional climate model REMO show no significant change of the yearly precipitation sum for the time period 2071-2100 compared to the reference period 1961-1990, but this tendency can differ on seasonal scale. The largest changes are expected for summer, both for the precipitation means and extremes. For the end of the 21st century summer precipitation sum is projected to decrease by 18 %. The frequency of hourly precipitation sums exceeding 0.1 mm can decrease by up to 30 %. The 95th percentile value may be higher, which refer to the increase of the rainfall intensity. The projected change of the temporal distribution of precipitation, the

  6. The prominent 1.6-year periodicity in solar motion due to the inner planets

    Czech Academy of Sciences Publication Activity Database

    Charvátová, Ivanka

    2007-01-01

    Roč. 25, č. 5 (2007), s. 1227-1232 ISSN 0992-7689 R&D Projects: GA AV ČR(CZ) IAA300120608 Institutional research plan: CEZ:AV0Z30120515 Keywords : solar-planetary relationships * solar physics * celestial mechanis Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 1.427, year: 2007

  7. On the formation of elliptic stones due to periodic water waves

    Science.gov (United States)

    Winzer, Klaus

    2013-11-01

    On the beaches of the oceans may be found amongst many stones with irregular shapes also stones that are nearly perfect ellipsoids. In this work, two grinding processes in the surf for stones of ellipsoidal shape are described mathematically on the basis of simple physical models. The first process is the abrasion of material perpendicular to the shortest axis of the stone sliding on the sand of the beach. The model explains the experimental fact that oblong stones with small b/ a-ratios as a rule are slim stones with a small c/ a-ratio. The second process is connected with a rolling motion around the axis of the largest moment of inertia, which leads to an effective grinding on a surface strip perpendicular to the ab-plane. The corresponding calculation yields a criterion for the form stability of the ellipsoid. The obtained result is virtually identical with the experimentally observed maximum of the error distribution function for the b/ a-ratio.

  8. 76 FR 81834 - Extension of Statutory Period for Compensation for Certain Disabilities Due to Undiagnosed...

    Science.gov (United States)

    2011-12-29

    ... unexplained chronic multi-symptom illness (such as chronic fatigue syndrome, fibromyalgia, and irritable bowel syndrome) that is defined by a cluster of signs and symptoms; or (c) any diagnosed illness that the...

  9. Special event planning for the emergency manager.

    Science.gov (United States)

    Gaynor, Peter T

    2009-11-01

    In the domain of emergency management and homeland security there is a lack of a formal planning process at the local level when it comes to special event planning. The unique nature of special event planning demands an understanding of the planning process for both traditional and non-traditional planning partners. This understanding will make certain that local governments apply due diligence when planning for the safety of the public. This paper offers a practical roadmap for planning at the local level. It will address those 'special events' that are beyond routine local events but not of a sufficient scale to be granted National Special Security Event status. Due to the infrequency of 'special events' in most communities, it is imperative that deliberate planning takes place. Upon conclusion, the reader will be able to construct a planning process tailored to the needs of their community, guide both traditional and non-traditional planning partners through the planning process, determine priorities, explore alternatives, plan for contingencies, conduct a confirmation brief, facilitate operations and assemble an after-action report and improvement plan.

  10. Event dependent sampling of recurrent events

    DEFF Research Database (Denmark)

    Kvist, Tine Kajsa; Andersen, Per Kragh; Angst, Jules

    2010-01-01

    retrospective and prospective disease course histories are used. We examine two methods to correct for the selection depending on which data are used in the analysis. In the first case, the conditional distribution of the process given the pre-selection history is determined. In the second case, an inverse......-probability-of-selection weighting scheme is suggested. The ability of the methods to correct for the bias due to selection is investigated with simulations. Furthermore, the methods are applied to affective disease data from a register-based study (Kessing et al. Br J Psychiatry 185:372-377, 2004a) and from a long-term clinical...

  11. First Indico Virtual Event

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    The first Indico virtual event will take place on February 4th 15:00 and will focus on two main topics The release of Indico v1.2 The migration of the OO Indico backend database (ZODB) to a more standard DBMS It will be fully virtual using the CERN Vidyo service and will foster discussions between developers and administrators of Indico servers worldwide. Connections to the virtual room will be open, but attendees are encouraged to register to the event, in order to be informed of any changes in the organisation if any. If you would like to add a topic of discussion or propose yourself a contribution, please let us know at indico-team@cern.ch. Connection to Vidyo Vidyo connection details are available here CERN Vidyo service documentation can be found here First-time users are encouraged to try the service before connecting to the real event

  12. Discrete-Event Simulation

    Directory of Open Access Journals (Sweden)

    Prateek Sharma

    2015-04-01

    Full Text Available Abstract Simulation can be regarded as the emulation of the behavior of a real-world system over an interval of time. The process of simulation relies upon the generation of the history of a system and then analyzing that history to predict the outcome and improve the working of real systems. Simulations can be of various kinds but the topic of interest here is one of the most important kind of simulation which is Discrete-Event Simulation which models the system as a discrete sequence of events in time. So this paper aims at introducing about Discrete-Event Simulation and analyzing how it is beneficial to the real world systems.

  13. Anomalous Kolar events revisited: Dark matter?

    Indian Academy of Sciences (India)

    2014-03-06

    Mar 6, 2014 ... due to the decays of dark matter particles of mass in the range of 5–10 GeV, is pointed out. Keywords. Dark matter; Kolar ... possibility that these events may be caused by the decay of dark matter particles and make some remarks ..... [16] Particle Data Group: J Beringer et al, Phys. Rev. D 86, 010001 (2012).

  14. Period Variations for the Cepheid VZ Cyg

    Science.gov (United States)

    Sirorattanakul, Krittanon; Engle, Scott; Pepper, Joshua; Wells, Mark; Laney, Clifton D.; Rodriguez, Joseph E.; Stassun, Keivan G.

    2017-12-01

    The Cepheid Period-Luminosity law is a key rung on the extragalactic distance ladder. However, numerous Cepheids are known to undergo period variations. Monitoring, refining, and understanding these period variations allows us to better determine the parameters of the Cepheids themselves and of the instability strip in which they reside, and to test models of stellar evolution. VZ Cyg, a classical Cepheid pulsating at ˜4.864 days, has been observed for over 100 years. Combining data from literature observations, the Kilodegree Extremely Little Telescope (KELT) transit survey, and new targeted observations with the Robotically Controlled Telescope (RCT) at Kitt Peak, we find a period change rate of dP/dt = -0.0642 ± 0.0018 s yr-1. However, when only the recent observations are examined, we find a much higher period change rate of dP/dt = -0.0923 ± 0.0110 s yr-1. This higher rate could be due to an apparent long-term (P ≈ 26.5 years) cyclic period variation. The possible interpretations of this single Cepheid’s complex period variations underscore both the need to regularly monitor pulsating variables and the important benefits that photometric surveys such as KELT can have on the field. Further monitoring of this interesting example of Cepheid variability is recommended to confirm and better understand the possible cyclic period variations. Further, Cepheid timing analyses are necessary to fully understand their current behaviors and parameters, as well as their evolutionary histories.

  15. Genetic stratigraphy of key demographic events in Arabia.

    Science.gov (United States)

    Fernandes, Verónica; Triska, Petr; Pereira, Joana B; Alshamali, Farida; Rito, Teresa; Machado, Alison; Fajkošová, Zuzana; Cavadas, Bruno; Černý, Viktor; Soares, Pedro; Richards, Martin B; Pereira, Luísa

    2015-01-01

    At the crossroads between Africa and Eurasia, Arabia is necessarily a melting pot, its peoples enriched by successive gene flow over the generations. Estimating the timing and impact of these multiple migrations are important steps in reconstructing the key demographic events in the human history. However, current methods based on genome-wide information identify admixture events inefficiently, tending to estimate only the more recent ages, as here in the case of admixture events across the Red Sea (~8-37 generations for African input into Arabia, and 30-90 generations for "back-to-Africa" migrations). An mtDNA-based founder analysis, corroborated by detailed analysis of the whole-mtDNA genome, affords an alternative means by which to identify, date and quantify multiple migration events at greater time depths, across the full range of modern human history, albeit for the maternal line of descent only. In Arabia, this approach enables us to infer several major pulses of dispersal between the Near East and Arabia, most likely via the Gulf corridor. Although some relict lineages survive in Arabia from the time of the out-of-Africa dispersal, 60 ka, the major episodes in the peopling of the Peninsula took place from north to south in the Late Glacial and, to a lesser extent, the immediate post-glacial/Neolithic. Exchanges across the Red Sea were mainly due to the Arab slave trade and maritime dominance (from ~2.5 ka to very recent times), but had already begun by the early Holocene, fuelled by the establishment of maritime networks since ~8 ka. The main "back-to-Africa" migrations, again undetected by genome-wide dating analyses, occurred in the Late Glacial period for introductions into eastern Africa, whilst the Neolithic was more significant for migrations towards North Africa.

  16. Events Marketing Model of Dubai Shopping Festival

    Directory of Open Access Journals (Sweden)

    K. Prakash Vel

    2014-12-01

    Full Text Available Cities and places have become major destinations through taking the extra mile of creativity and offering a well-researched package of offerings through systematically planned events. One such leading example in the list of successful festivals that have earned a global reputation due to its uniqueness and creative event offerings is the Dubai Shopping Festival (DSF in the United Arab Emirates. This paper is a case study based description of the internal and external drivers involved in planning and implementing a global event successfully and has captured the various drivers through a structured framework. The analysis serves as a good addition to the existing literature on ‘Events Marketing’. 

  17. Aspirin and the risk of cardiovascular events in atherosclerosis patients with and without prior ischemic events.

    Science.gov (United States)

    Bavry, Anthony A; Elgendy, Islam Y; Elbez, Yedid; Mahmoud, Ahmed N; Sorbets, Emmanuel; Steg, Philippe Gabriel; Bhatt, Deepak L

    2017-09-01

    The benefit of aspirin among patients with stable atherosclerosis without a prior ischemic event is not well defined. Aspirin would be of benefit in outpatients with atherosclerosis with prior ischemic events, but not in those without ischemic events. Subjects from the Reduction of Atherothrombosis for Continued Health registry were divided according to prior ischemic event (n =21 724) vs stable atherosclerosis, but no prior ischemic event (n = 11 872). Analyses were propensity score matched. Aspirin use was updated at each clinic visit and considered as a time-varying covariate. The primary outcome was the first occurrence of cardiovascular death, myocardial infarction, or stroke. In the group with a prior ischemic event, aspirin use was associated with a marginally lower risk of the primary outcome at a median of 41 months (hazard ratio [HR]: 0.81, 95% confidence interval [CI]: 0.65-1.01, P = 0.06). In the group without a prior ischemic event, aspirin use was not associated with a lower risk of the primary outcome at a median of 36 months (HR: 1.03, 95% CI: 0.73-1.45, P = 0.86). In this observational analysis of outpatients with stable atherosclerosis, aspirin was marginally beneficial among patients with a prior ischemic event; however, there was no apparent benefit among those with no prior ischemic event. © 2017 Wiley Periodicals, Inc.

  18. Lunar Phases and Emergency Department Visits for Renal Colic Due to Ureteral Calculus.

    Directory of Open Access Journals (Sweden)

    Andy W Yang

    Full Text Available Urolithiasis affects an estimated 5% of the population and the lifetime risk of passing a stone in the urinary tract is estimated to be 8-10%. Urinary calculus formation is highly variable and while certain risk factors such as age, gender, seasonality, anatomic abnormality, and metabolic diseases have been identified, not much is known regarding the association of environmental factors such as lunar phases on renal colic. We conducted a retrospective study to test the hypothesis that full moon phase is an environmental factor associated for increased emergency department (ED visits for renal colic due to ureteral calculus.We analyzed 559 renal colic diagnoses by the ED at the University of Nebraska Medical Center in a 24-month period and compared them with corresponding lunar phases as well as supermoon events. The lunar phases were defined as full moon ± two days, new moon ± two days, and the days in-between as normal days according to the lunar calendar. Supermoon event dates were obtained from NASA.90 cases (16.1% were diagnosed during full moon phase, 89 cases (15.9% were diagnosed during new moon phase, and 380 cases (68.0% were diagnosed during normal days. The incidence of renal colic showed no statistically significant association with lunar phases or supermoon events.In this retrospective longitudinal study with adequate power, neither full moon phase nor supermoon event exhibited an association with increased renal colic diagnoses due to ureteral calculus by the ED at the University of Nebraska Medical Center.

  19. Conferences and Events

    International Development Research Centre (IDRC) Digital Library (Canada)

    André Lavoie

    2017-06-28

    Jun 28, 2017 ... Training events that relate to ensuring that employees are qualified to perform their assigned duties – for instance, acquiring or maintaining professional accreditations of recognized professional bodies as required by the employees to practice their profession; and membership to such professional bodies;.

  20. The ATLAS event filter

    CERN Document Server

    Beck, H P; Boissat, C; Davis, R; Duval, P Y; Etienne, F; Fede, E; Francis, D; Green, P; Hemmer, F; Jones, R; MacKinnon, J; Mapelli, Livio P; Meessen, C; Mommsen, R K; Mornacchi, Giuseppe; Nacasch, R; Negri, A; Pinfold, James L; Polesello, G; Qian, Z; Rafflin, C; Scannicchio, D A; Stanescu, C; Touchard, F; Vercesi, V

    1999-01-01

    An overview of the studies for the ATLAS Event Filter is given. The architecture and the high level design of the DAQ-1 prototype is presented. The current status if the prototypes is briefly given. Finally, future plans and milestones are given. (11 refs).

  1. Print Centre Event 2

    OpenAIRE

    Hadbavny, Michelle

    2012-01-01

    During Institutions by Artists, Fillip was pleased to present a series of free, parallel events in the lobby of SFU Woodward’s that investigated the material culture produced by the institutional practices of artists. The Print Centre featured talks, launches, and screenings by conference presenters and attendees. Presented in collaboration with a temporary book store hosted by Motto Books (Berlin).

  2. Print Centre Event 3

    OpenAIRE

    Hadbavny, Michelle

    2012-01-01

    During Institutions by Artists, Fillip was pleased to present a series of free, parallel events in the lobby of SFU Woodward’s that investigated the material culture produced by the institutional practices of artists. The Print Centre featured talks, launches, and screenings by conference presenters and attendees. Presented in collaboration with a temporary book store hosted by Motto Books (Berlin).

  3. Language As Social Event.

    Science.gov (United States)

    Harste, Jerome C.

    A taxonomy developed for the study of the growth and development of written language from the perspective of social event was tested with a group of 68 children, aged three to six years. The subjects were presented with a wide variety of environmental print messages (road signs, toys, fast food signs, and household products) and were questioned…

  4. Business Event Notification Service (BENS)

    Data.gov (United States)

    Department of Veterans Affairs — BENS provides a notification of pre-defined business events to applications, portals, and automated business processes. Such events are defined in the Event Catalog,...

  5. Event-Based Activity Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2004-01-01

    We present and discuss a modeling approach that supports event-based modeling of information and activity in information systems. Interacting human actors and IT-actors may carry out such activity. We use events to create meaningful relations between information structures and the related...... activities inside and outside an IT-system. We use event-activity diagrams to model activity. Such diagrams support the modeling of activity flow, object flow, shared events, triggering events, and interrupting events....

  6. Concurrent hypokalemic periodic paralysis and bipolar disorder

    Directory of Open Access Journals (Sweden)

    Chia-Lin Lin

    2015-01-01

    Full Text Available Primary periodic paralysis is a rare autosomal dominant disorder of ion-channel dysfunction, manifested by episodic flaccid paresis secondary to abnormal sarcolemma excitability. Membrane destabilization involving Na, K-ATPase has been hypothesized to be a biological etiology of the bipolar disorder (BD and the mechanisms underlying lithium therapy have been linked to it. To date, there has been only one reported case of BD comorbid with periodic paralysis. Herein, we reported another case of concurrent bipolar mania and hypokalemic periodic paralysis (HPP, one special form of periodic paralysis. Consistent with the previous case, our patient responded well to lithium treatment for both bipolar mania and HPP. This might provide some support to the hypothesis that the therapeutic effects of lithium in both BD and HPP could be due to the correction of the underlying common pathophysiology.

  7. Agriculture: Natural Events and Disasters

    Science.gov (United States)

    Natural Events and DiasastersInformation on Natural Events and Disasters. Every year natural disasters, such as hurricanes, floods, fires, earthquakes, and tornadoes, challenge agricultural production.

  8. Hydrodynamic modelling of extreme flood events in the Kashmir valley in India

    Science.gov (United States)

    Jain, Manoj; Parvaze, Sabah

    2017-04-01

    Floods are one of the most predominant, costly and deadly hazards of all natural vulnerabilities. Every year, floods exert a heavy toll on human life and property in many parts of the world. The prediction of river stages and discharge during flood extremes plays a vital role in planning structural and non-structural measures of flood management. The predictions are also valuable to prepare the flood inundation maps and river floodplain zoning. In the Kashmir Valley, floods occur mainly and very often in the Jhelum Basin mostly due to extreme precipitation events and rugged mountainous topography of the basin. These floods cause extreme damage to life and property in the valley from time to time. Excessive rainfall, particularly in higher sub-catchments causes the snow to melt resulting in excessive runoff downhill to the streams causing floods in the Kashmir Valley where Srinagar city is located. However, very few hydrological studies have been undertaken for the Jhelum Basin mainly due to non-availability of hydrological data due to very complex mountainous terrain. Therefore, the present study has been conducted to model the extreme flood events in the Jhelum Basin in Kashmir Valley. An integrated NAM and MIKE 11 HD model has been setup for Jhelum basin up to Ram Munshi Bagh gauging site and then four most extreme historical flood events in the time series has been analyzed separately including the most recent and most extreme flood event of 2014. In September 2014, the Kashmir Valley witnessed the most severe flood in the past 60 years due to catastrophic rainfall from 1st to 6th September wherein the valley received unprecedented rainfall of more than 650 mm in just 3 days breaking record of many decades. The MIKE 11 HD and NAM model has been calibrated using 21 years (1985-2005) data and validated using 9 years (2006-2014) data. The efficiency indices of the model for calibration and validation period is 0.749 and 0.792 respectively. The model simulated

  9. Antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus

    Energy Technology Data Exchange (ETDEWEB)

    Subramanian, Subramanian; Sharma, Raju; Gamanagatti, Shivanand [All India Institute of Medical Sciences, Department of Radiodiagnosis, New Delhi (India); Agarwala, Sandeep [All India Institute of Medical Sciences, Department of Pediatric Surgery, New Delhi (India); Gupta, Prerna; Kumar, Sunesh [All India Institute of Medical Sciences, Department of Obstetrics and Gynaecology, New Delhi (India)

    2006-10-15

    Hydrometrocolpos is cystic dilatation of the vagina and uterus due to congenital vaginal obstruction. It may be secretory or urinary in character and manifests in the neonatal period with abdominal distension. Urinary hydrometrocolpos occurs in patients with urogenital sinus or cloacal anomaly. A rare case of antenatal MR diagnosis of urinary hydrometrocolpos due to urogenital sinus is presented. (orig.)

  10. The Method of Event Determination Registered on the Event Source

    OpenAIRE

    Aleksandr Vasilevich Kuznetcov

    2016-01-01

    In this article the method of event determination registered into audit trails on the event source based on solution of linear programming task is described. This method allows optimizing the event management process within an information security management system by quantity of incidents. This method considers restrictions related to performance of the event source.

  11. The Method of Event Determination Registered on the Event Source

    Directory of Open Access Journals (Sweden)

    Aleksandr Vasilevich Kuznetcov

    2016-03-01

    Full Text Available In this article the method of event determination registered into audit trails on the event source based on solution of linear programming task is described. This method allows optimizing the event management process within an information security management system by quantity of incidents. This method considers restrictions related to performance of the event source.

  12. Model space of economic events

    Science.gov (United States)

    Romanovsky, M. Yu.

    A method for constructing the model or virtual space of economic events when economic objects can be considered as material ones is suggested. We describe change of share rates in time at stock markets as the potential difference of attracted bodies in time in this virtual space. Each share of each enterprise is displayed by a single particle with a unit “charge”. It is shown that the random value of potential difference at the origin of coordinates measured at a definite time interval has the probability density coinciding with the known distribution of “Levy flights” or “Levy walks”. A distribution of alteration in time of the “Standard and Poor” index value obtained by Mantegna and Stanley (they shown that it is the “Levy walks” distribution too) (Mantegna and Stanley, Nature 376 (1995) 46) is used for determination of the introduced potential dependence on coordinates in the model space. A simple phenomenological model of interaction potential is introduced. The potential law of each particle turns out to be closed to r-2.14 in the minimum possible three-dimensional model space. This model permits calculation of time of random potential correlations at a certain point of the model space. These correlations could characterize the time period of making a decision by an investor at stock exchange. It is shown that this time is notably shorter in unstable periods (1987). A “microscopical” model of interaction in the virtual space is also discussed.

  13. Short-Period Seismometer Development at JPL

    Science.gov (United States)

    Martin, R.

    1995-01-01

    Determining the structure of the interior of Mars has been a high priority for every Mars exploration strategy developed in the past 20 years, and is one of the primary goals of the InterMarsnet mission. Seismology is by far the most effective and detailed tool for investigating the radial and lateral distribution of density and elastic properties within a planet. Whereas long-period signals contain information from surface waves and normal modes from relatively large events, as well as the tidal response of the planet, the ability to record the high-frequency portion of the seismic spectrum (0.05 > f > 50 Hz) is essential for using the body waves of small to moderate events for probing the interior and analyzing the source characteristics of martian quakes.

  14. PLUTO-CHARON MUTUAL EVENTS V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — During the period 1985-1990, the earth entered the orbital plane of Pluto and its moon Charon, and the mutual eclipse events were observed from ground-based...

  15. Hydrological Alterations Due to Climate-Induced Regional Vegetation Change

    Science.gov (United States)

    White, A. B.; Vivoni, E. R.; Springer, E. P.

    2010-12-01

    An extended, severe drought in the southwestern U.S. from 2000 to 2003 was accompanied by increased temperatures and bark beetle infestations, inducing the large-scale mortality of woody overstory (Pinus edulis). The consequential redistribution of water, radiation, and nutrient availability modified the ecosystem phenology, species composition, and forced the ecosystem to transition into a new state. We hypothesize that the hydrological processes in the ecosystem were also altered due to the mortality. Thus, our objective is to investigate changes in the soil-vegetation-atmosphere continuum at the watershed scale. The Rio Ojo Caliente Basin is a subbasin of the Upper Rio Grande, located mostly in New Mexico, and is approximately 1,000 km2. Examining a remotely-sensed vegetation index (1-km AVHRR NDVI from 1990 to 2006), there is an increasing trend in the NDVI from 1989 to 1999 (pre-mortality period), a decreasing trend from 2000 to 2003 (mortality period), and a dramatic increasing trend from 2004 to 2006 (post-mortality period) in which the NDVI rebounds to nearly pre-mortality magnitudes. This pattern exists across varying spatial scales (plot to watershed to region) and signifies a profound alteration in the ecosystem, for while the vegetation composition was altered to a great degree, the system rapidly returned to a homeostatic state balancing resource supply and use during the post-mortality period. To investigate hydrological changes due to the mortality, we employ a physically-based, distributed hydrologic model, tRIBS (TIN-based Real-Time Integrated Basin Simulator) for the Rio Ojo Caliente Basin. STATSGO 1-km soils data, 10-meter National Elevation Dataset DEMs, Carson National Forest vegetation species data, and MM5-downscaled NCEP/NCAR Reanalysis-I meteorologic data are used as model inputs. A combination of MODIS and AVHRR remote-sensing data, values from the literature, and field data from a long-term, pi {n}on-juniper (PJ) observation site in Los

  16. Chelyabinsk event: injuries

    Science.gov (United States)

    Kartashova, A.; Popova, O.; Jenniskens, P.; Glazachev, D.

    2017-09-01

    In the morning of 2013 February 15 (at 3:20 UT), a relatively large ( 20m) meteoroid entered the Earth atmosphere in the Chelyabinsk Region of Russia and caused an airburst strong enough to create widespread glass damage. This event was observed by numerous eye witnesses. Most recent tally shows that 1613 people asked for medical assistance at hospitals. This paper presents data of injuries of the Chelyabinsk meteoroid obtained through interviews of eyewitnesses and from the official sources.

  17. Sport event marketing plan

    Directory of Open Access Journals (Sweden)

    Gašović Milan

    2007-01-01

    Full Text Available A marketing plan details how an event organization will compete in the marketplace in terms of its service offerings, promotions and evaluation. During the first stage of the marketing plan process, a number of its consumers (current, former and prospective and competitors. Marketing objectives are developed and implemented using an action plan. The marketing plan objectives are evaluated using an objective-discrepancy approach to determine the extent to which they were attained.

  18. Intercorporate Security Event Correlation

    Directory of Open Access Journals (Sweden)

    D. O. Kovalev

    2010-03-01

    Full Text Available Security controls are prone to false positives and false negatives which can lead to unwanted reputation losses for the bank. The reputational database within the security operations center (SOC and intercorporate correlation of security events are offered as a solution to increase attack detection fidelity. The theses introduce the definition and structure of the reputation, architectures of reputational exchange and the place of intercorporate correlation in overall SOC correlation analysis.

  19. The role of endothelial progenitor cells in transient ischemic attack patients for future cerebrovascular events

    Directory of Open Access Journals (Sweden)

    Rokhsareh Meamar

    2016-01-01

    Full Text Available Background: The role of endothelial progenitor cells (EPCs in the maintenance of vascularization following ischemic brain after experimental stroke has been established. Accordingly, in this study, we evaluated the role of circulating EPCs in transient ischemic attack (TIA patients for future cerebrovascular (CV events. Materials and Methods: The level of circulating EPCs (staining markers: CD34, CD309 were determined using flow cytometry at 24 h after TIA in thirty consecutive patients. The EPCs level was also evaluated once in thirty healthy volunteers. Over a period of 12 months, all patients were evaluated by an experienced neurologist for recurrent TIA, stroke or death induced by CV disorders. Results: Circulating EPCs increased in patients group following the first attack of TIA when compared with controls. By analysis of covariance, cardiovascular event history, hyperlipidemia, and statin therapy remained significant independent predictors of EPCs. The mean (standard deviation duration of follow-up was 10.5 (3.1 months (range, 2–12 months. During follow-up, a total of three patients died due to CV accident and four patients experienced again recurrent TIA. By analyzing data with Cox regression, EPC did not predict the future CV events in TIA patients. Conclusion: Increased incidence of future CV events did not occur in those patients with elevated EPCs in the first attack of TIA. The significant predicting factors of EPCs were cardiovascular event history, hyperlipidemia, and statin therapy.

  20. Extreme Events in Space Weather: Long-Range Correlations and Clustering

    Science.gov (United States)

    Sharma, S.; Veeramani, T.

    2008-12-01

    Space weather is driven by the solar wind and many extreme geomagnetic events such as space storms and substorms are potential natural hazards. The statistical studies of these vents are complicated because of the turbulent nature of their driver, the solar wind. On the other hand archived data of geospace storms and substorms for very long periods are available and are amenable to detailed analysis using many techniques. For example, a database of substorms consisting of more than million events have been compiled for this study of the inherent statistical characteristics of extreme events in geospace. The auto- correlation and mutual-information functions are used to obtain the scaling exponents and they show the presence of long-term correlations and clustering. The scaling is represented by two exponents, the break arising due mainly to the turbulent nature of the solar wind driving the events. The auto-correlation functions show stronger long-term correlation than the mutual information functions, which represent correlations of all orders. The return intervals for varying thresholds show long-range correlations with decreasing strength for higher thresholds, similar to the case of multifractal systems. The techniques of detrended fluctuation analysis are used to further study of the long-range correlations and clustering of geospace events.

  1. LHCb Event display

    CERN Document Server

    Trisovic, Ana

    2014-01-01

    The LHCb Event Display was made for educational purposes at the European Organization for Nuclear Research, CERN in Geneva, Switzerland. The project was implemented as a stand-alone application using C++ and ROOT, a framework developed by CERN for data analysis. This paper outlines the development and architecture of the application in detail, as well as the motivation for the development and the goals of the exercise. The application focuses on the visualization of events recorded by the LHCb detector, where an event represents a set of charged particle tracks in one proton-proton collision. Every particle track is coloured by its type and can be selected to see its essential information such as mass and momentum. The application allows students to save this information and calculate the invariant mass for any pair of particles. Furthermore, the students can use additional calculating tools in the application and build up a histogram of these invariant masses. The goal for the students is to find a $D^0$ par...

  2. Probability Estimates of Solar Proton Doses During Periods of Low Sunspot Number for Short Duration Missions

    Science.gov (United States)

    Atwell, William; Tylka, Allan J.; Dietrich, William F.; Rojdev, Kristina; Matzkind, Courtney

    2016-01-01

    In an earlier paper presented at ICES in 2015, we investigated solar particle event (SPE) radiation exposures (absorbed dose) to small, thinly-shielded spacecraft during a period when the monthly smoothed sunspot number (SSN) was less than 30. Although such months are generally considered "solar-quiet", SPEs observed during these months even include Ground Level Events, the most energetic type of SPE. In this paper, we add to previous study those SPEs that occurred in 1973-2015 when the SSN was greater than 30 but less than 50. Based on the observable energy range of the solar protons, we classify the event as GLEs, sub-GLEs, and sub-sub-GLEs, all of which are potential contributors to the radiation hazard. We use the spectra of these events to construct a probabilistic model of the absorbed dose due to solar protons when SSN < 50 at various confidence levels for various depths of shielding and for various mission durations. We provide plots and tables of solar proton-induced absorbed dose as functions of confidence level, shielding thickness, and mission-duration that will be useful to system designers.

  3. Photolysis of Periodate and Periodic Acid in Aqueous Solution

    DEFF Research Database (Denmark)

    Sehested, Knud; Kläning, U. K.

    1978-01-01

    The photochemistry of periodate and periodic acid in aqueous solution was studied (i) by quantum yield measurements at low light intensity (ii) by flash photolysis, and (iii) by photolysis of glassy samples at 77 K. The photochemical studies were supplemented with pulse radiolysis studies...... of aqueous periodate solutions and with kinetic studies using stopped-flow technique. In strongly alkaline solution the photodecomposition of periodate proceeds via formation of O– and IVI. At pH

  4. Mode of Strong Earthquake Recurrence In Central Ionian Islands (greece). Possible Triggering Due To Coulomb Stress Changes Generated By The Occurrence of Previous Strong Shocks

    Science.gov (United States)

    Papadimitriou, E.

    The spatial-temporal distribution of shallow strong (M>6.3) earthquakes occurring in the area of central Ionian Islands is analyzed. These shocks generated on two adja- cent fault segments with different strike, but both associated with strike-slip faulting, constituting the boundary between continental collision to the north and oceanic sub- duction to the south. Seismic activity is confined in short time intervals alternating by much longer relatively quiescent periods. Each active period consists of a relatively large event or series (two to four) of events occurring closely both in space and time. This alteration was observed to happen four times since 1867, from when complete data exist for the study area. Since the phenomenon is not strictly periodic and during each active period multiple events occurred, it is attempted to interpret the seismic behavior on the basis of possible triggering. It is then investigated how changes in Coulomb Failure Function (DCFF) associated with one or more earthquakes may trig- ger subsequent events. Both the coseismic slip due to the generation of the strong earthquakes and stress build up associated with the two major fault segments were taken into account for the DCFF calculation. Earthquakes can be modeled as static dislocations in elastic half-space, and the stress pattern has been inverted according to the geometry and slip of each of the faults that ruptured in the chain of events. These calculations show that 13 out of 14 earthquakes with M>6.3 were preceded by a static stress change that encouraged failure. The magnitude of the stress increases transferred from one earthquake to another ranged from 0.01 MPa (0.1 bar) to over 0.1 MPa (1 bar). Maps of current DCFF provide additional information to long-term earthquake prediction. Areas of positive DCFF have been identified at two sites in Ke- falonia and Lefkada faults, respectively, where the next strong events are expected to occur.

  5. Adverse drug events leading to emergency department visits at an eye hospital: A brief report.

    Science.gov (United States)

    Alizadeh, Safa; Mohebbi, Niayesh; Gholami, Kheirollah; Jabbarvand, Mahmoud

    2017-06-01

    To evaluate adverse drug events (ADEs) resulting in emergency department visits in an eye hospital. Emergency department visits at Farabi Eye Hospital were assessed for a 7-day period. The patients' eye disorders and drug history were evaluated to detect ADEs. Of 1631 emergency visits, 5 (0.3%, 95% CI: 0.13-0.71%) were drug related. Tetracaine eye drops accounted for 4 (80%, 95% CI: 38-96%) cases with corneal involvement. The other case was an intense conjunctival injection due to naphazoline eye drops. ADEs should be considered in differential diagnosis of ocular emergency problems and preventive measure should be considered.

  6. Late Devonian Anoxia Events in the Central Asian Orogenic Belt: a Global Phenomenon

    Science.gov (United States)

    Carmichael, S. K.; Waters, J. A.; Suttner, T. J.; Kido, E.; DeReuil, A. A.; Moore, L. M.; Batchelor, C. J.

    2013-12-01

    Atmospheric CO2 values decreased dramatically during the Middle Devonian due to the rapid rise of land plants. These changing environmental conditions resulted in widespread anoxia and extinction events throughout the Late Devonian, including the critical Kellwasser and Hangenberg anoxia events, which are associated with major mass extinctions at both the beginning and end of the Famennian Stage of the Late Devonian. Fammenian sediments in northwestern Xinjiang Province, China, represent a highly fossiliferous shallow marine setting associated with a Devonian oceanic island arc complex. Analysis of multiple geochemical proxies (such as U/Th, Ba, normalized P2O5, V/Cr, Zr), magnetic susceptibility, and mineralogical data (biogenic apatite and pyrite framboids) indicates that these Famennian sequences record not only the Upper Kellwasser Anoxic Event at the Frasnian/Famennian (F/F) boundary but also the rebound from the F/F extinction event. Preliminary evidence suggests that the Hangenberg Anoxic Event can also be recognized in the same sequence, although our biostratigraphic control is less precise. Previous studies of the Kellwasser and Hangenberg Events have been performed on continental shelf environments of Laurussia, Gondwana, Siberia, and South China. The Devonian formations of northwest Xinjiang in this study, however, are part of the Central Asian Orogenic Belt (CAOB), which is thought to have formed as part of a complex amalgamation of intra-oceanic island arcs and continental fragments prior to the end of the latest Carboniferous. These results allow us to confirm the presence of the Kellwasser and Hangenberg Events in the open oceanic part of Paleotethys, indicating that both events were global in scope. The presence of an abundant diverse Famennian fauna between these anoxia/extinction events suggests that the shallow marine ecosystems in the CAOB were somewhat protected due to their tectonic location and relative isolation within an open ocean system

  7. [Data on mortality from external causes and events of undetermined intent, Paraná State, Brazil, 1979 to 2005].

    Science.gov (United States)

    Lozada, Elizabeth Mitiko Konno de; Mathias, Thais Aidar de Freitas; Andrade, Selma Maffei de; Aidar, Tirza

    2009-01-01

    This study analyzed the quality of data from the Mortality Information System (SIM) for deaths due to external causes in the State of Paraná, Brazil, 1979 to 2005, focusing on events of undetermined intent. Deaths were grouped in motor vehicle accidents, homicides, suicides, and events of undetermined intent, and proportional mortality and relative annual variation of rates over the three-year period were analyzed. Motor vehicle accidents (more than 30% of the total) were the most frequent causes of death throughout the period, and since 1997 homicides have become the second most frequent cause. Deaths due to events of undetermined intent caused by weapons (firearms or knives) decreased from 4.8% in 1981 to 0.3% in 2005. Mortality rates for events of undetermined intent (overall) decreased from 14.9 deaths per 100,000 inhabitants in 1979-81 to 2.0 in 2003-05. Annual percentage variation was -13.1% from 1980 to 1985, -6% from 1996 to 2000, and -11% from 2000 to 2004. The findings show the good quality of SIM data on external causes in the State of Paraná, allowing analyses with the potential to support programs to prevent injuries as well as health promotion measures.

  8. Event reconstruction algorithms for the ATLAS trigger

    CERN Document Server

    Fonseca-Martin, T; Adragna, P; Aleksandrov, E; Aleksandrov, I; Amorim, A; Anderson, K; Anduaga, X; Aracena, I; Asquith, L; Avolio, G; Backlund, S; Badescu, E; Baines, J; Barria, P; Bartoldus, R; Batreanu, S; Beck, H P; Bee, C; Bell, P; Bell, W H; Bellomo, M; Benslama, K; Berge, D; Berger, N; Berry, T; Biglietti, M; Blair, R R; Bogaerts, A; Bold, T; Bosman, M; Boyd, J; Brelier, B; Burckhart-Chromek, D; Buttar, C; Campanelli, M; Caprini, M; Carlino, G; Casadei, D; Casado, M P; Cataldi, G; Cimino, D; Ciobotaru, M; Clements, D; Coccaro, A; Conde-Muíño, P; Conventi, F; Corso-Radu, A; Costa, M J; Coura Torres, R; Cranfeld, R; Cranmer, K; Crone, G; Dam, M; Damazio, D; Dawson, I; Dawson, J; De Almeida Simoes, J; De Cecco, S; De Santo, A; DellaPietra, M; Delsart, P A; Demers, S; Demirkoz, B; Di Mattia, A; Dionisi, C; Djilkibaev, R; Dobinson, R; Dobson, M; Dotti, A; Dova, M; Drake, G; Dufour, M A; Eckweiler, S; Ehrenfeld, W; Eifert, T; Ellis, Nick; Emeliyanov, D; Enoque Ferreira de Lima, D; Ermoline, Y; Eschrich, I; Facius, K; Falciano, S; Farthouat, P; Feng, E; Ferland, J; Ferrari, R; Ferrer, M L; Fischer, G; Francis, D; Gadomski, S; Garitaonandia Elejabarrieta, H; Gaudio, G; Gaumer, O; George, S; Giagu, S; Goncalo, R; Gorini, B; Gorini, E; Gowdy, S; Grabowska-Bold, I; Grancagnolo, S; Green, B; Haas, S; Haberichter, W; Hadavand, H; Haeberli, C; Haller, J; Hamilton, A; Hansen, J R; Hauschild, M; Hauser, R; Head, S; Hillier, S J; Höcker, A; Hrynóva, T; Hughes-Jones, R; Huston, J; Idarraga, J; Igonkina, O; Inada, M; Jain, V; Johns, K; Joos, M; Kama, S; Kanaya, N; Kazarov, A; Kehoe, R; Khoriauli, G; Kieft, G; Kilvington, G; Kirk, J; Kiyamura, H; Kolos, S; Kono, T; Konstantinidis, N; Korcyl, K; Kordas, K; Kotov, V; Krasznahorkay, A; Kubota, T; Kugel, A; Kuhn, D; Kurasige, H; Kuwabara, T; Kwee, R; Lankford, A; LeCompte, T; Leahu, L; Leahu, M; Ledroit, F; Lehmann-Miotto, G; Lei, X; Lellouch, D; Leyton, M; Li, S; Lim, H; Lohse, T; Losada, M; Luci, C; Luminari, L; Mapelli, L; Martin, B; Martin, B T; Marzano, F; Masik, J; McMahon, T; McPherson, R; Medinnis, M; Meessen, C; Meirosu, C; Messina, A; Mincer, A; Mineev, M; Misiejuk, A; Mönig, K; Monticelli, F; Moraes, A; Moreno, D; Morettini, P; Murillo Garcia, R; Nagano, K; Nagasaka, Y; Negri, A; Némethy, P; Neusiedl, A; Nisati, A; Nozicka, M; Omachi, C; Osculati, B; Osuna, C; Padilla, C; Panikashvili, N; Parodi, F; Pasqualucci, E; Pauly, T; Perera, V; Pérez, E; Pérez-Réale, V; Petersen, J; Piegaia, R; Pilcher, J E; Pinzon, G; Pope, B; Potter, C; Primavera, M; Radescu, V; Rajagopalan, S; Renkel, P; Rescigno, M; Rieke, S; Risler, C; Riu, I; Robertson, S; Roda, C; Rodríguez, D; Rogriquez, Y; Ryabov, Yu; Ryan, P; Salvatore, D; Santamarina, C; Santamarina-Rios, C; Scannicchio, D; Scannicchio, D A; Schiavi, C; Schlereth, J L; Scholtes, I; Schooltz, D; Scott, W; Segura, E; Shimbo, N; Sidoti, A; Siragusa, G; Sivoklokov, S; Sloper, J E; Smizanska, M; Soloviev, I; Soluk, R; Spagnolo, S; Spiwoks, R; Stancu, S; Steinberg, P; Stelzer, J; Stradling, A; Strom, David M; Strong, J; Su, D; Sushkov, S; Sutton, M; Szymocha, T; Tapprogge, S; Tarem, S; Tarem, Z; Teixeira-Dias, P; Tokoshuku, K; Torrence, E; Touchard, F; Tremblet, L; Tripiana, M; Usai, G; Vachon, B; Vandelli, W; Ventura, A; Vercesi, V; Vermeulen, J; Von Der Schmitt, J; Wang, M; Watson, A; Wengler, T; Werner, P; Wheeler-Ellis, S; Wickens, F; Wiedenmann, W; Wielers, M; Wilkens, H; Winklmeier, F; Woerling, E E; Wu, S L; Wu, X; Xella, S; Yamazaki, Y; Yu, M; Zema, F; Zhang, J; Zhao, L; Zobernig, H; Dos Anjos, A; Zur Nedden, M; Ozcan, E; Ünel, G

    2008-01-01

    The ATLAS experiment under construction at CERN is due to begin operation at the end of 2007. The detector will record the results of proton-proton collisions at a center-of-mass energy of 14 TeV. The trigger is a three-tier system designed to identify in real-time potentially interesting events that are then saved for detailed offline analysis. The trigger system will select approximately 200 Hz of potentially interesting events out of the 40 MHz bunch-crossing rate (with 109 interactions per second at the nominal luminosity).

  9. Large natural geophysical events: planetary planning

    Energy Technology Data Exchange (ETDEWEB)

    Knox, J.B.; Smith, J.V.

    1984-09-01

    Geological and geophysical data suggest that during the evolution of the earth and its species, that there have been many mass extinctions due to large impacts from comets and large asteroids, and major volcanic events. Today, technology has developed to the stage where we can begin to consider protective measures for the planet. Evidence of the ecological disruption and frequency of these major events is presented. Surveillance and warning systems are most critical to develop wherein sufficient lead times for warnings exist so that appropriate interventions could be designed. The long term research undergirding these warning systems, implementation, and proof testing is rich in opportunities for collaboration for peace.

  10. Identification of victims in extreme events

    Science.gov (United States)

    Talipova, Yu.; Polukhina, O.

    2009-04-01

    Catastrophic natural disasters including tsunami events are increased the frequency in last years. One of very important problems here is the identification of personality of the victims. Due to difficult identification of the dead bodies lied into water for a long time the analysis of tooth-jaw system is proposed to apply because teeth are extremely stable to the destructive actions of environment. The method of identification of the age, sex and race of victims based on the mathematic model of pattern recognition and collected database is described. Some examples from extreme sea wave events are analyzed.

  11. Atmospheric circulation patterns associated with strong wind events in Catalonia

    Science.gov (United States)

    Peña, J. C.; Aran, M.; Cunillera, J.; Amaro, J.

    2011-01-01

    The benefit of having a daily synoptic weather type catalogue and even more, a detailed catalogue for high impact weather events is well recognised by both climatologist and meteorologist communities. In this way the Meteorological Service of Catalonia (SMC) has produced some accurate classifications for extreme events, such as hailstorms or strong winds (SW). Within the framework of the MEDEX project, the SMC has been collaborating to increase the level of awareness about these events. Following this line of work, the aim of this study is to characterise the SW events in Catalonia. According to the guidelines of the MEDEX project we worked with its SW event database for the period June 1995 to May 2004. We also used the period 2005-2009 to test the methodology. The methodology is based on principal component, cluster and discriminant analyses and applied to four variables: SLP, temperature at 850 hPa and geopotential at 500 hPa on a synoptic-scale and local gust wind. We worked with ERA-Interim reanalysis and applied discriminant analysis to test the quality of the methodology and to classify the events of the validation period. We found seven patterns for the SW events. The strongest event corresponds to NW-Flow with the Azores Anticyclone and the passing of a low pressure through the Pyrenees. This methodology has distinguished the summer events in an independent cluster. The results obtained encourage us to follow this line of work.

  12. Civil protection and Damaging Hydrogeological Events: comparative analysis of the 2000 and 2015 events in Calabria (southern Italy)

    Science.gov (United States)

    Petrucci, Olga; Caloiero, Tommaso; Aurora Pasqua, Angela; Perrotta, Piero; Russo, Luigi; Tansi, Carlo

    2017-11-01

    Calabria (southern Italy) is a flood prone region, due to both its rough orography and fast hydrologic response of most watersheds. During the rainy season, intense rain affects the region, triggering floods and mass movements that cause economic damage and fatalities. This work presents a methodological approach to perform the comparative analysis of two events affecting the same area at a distance of 15 years, by collecting all the qualitative and quantitative features useful to describe both rain and damage. The aim is to understand if similar meteorological events affecting the same area can have different outcomes in terms of damage. The first event occurred between 8 and 10 September 2000, damaged 109 out of 409 municipalities of the region and killed 13 people in a campsite due to a flood. The second event, which occurred between 30 October and 1 November 2015, damaged 79 municipalities, and killed a man due to a flood. The comparative analysis highlights that, despite the exceptionality of triggering daily rain was higher in the 2015 event, the damage caused by the 2000 event to both infrastructures and belongings was higher, and it was strongly increased due to the 13 flood victims. We concluded that, in the 2015 event, the management of pre-event phases, with the issuing of meteorological alert, and the emergency management, with the preventive evacuation of people in hazardous situations due to landslides or floods, contributed to reduce the number of victims.

  13. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2009-01-01

    The purpose of the paper is to obtain insight into and provide practical advice for event-based conceptual modeling. We analyze a set of event concepts and use the results to formulate a conceptual event model that is used to identify guidelines for creation of dynamic process models and static...... information models. We characterize events as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms of information structures. The conceptual event model is used to characterize a variety of event concepts and it is used to illustrate how events can...... be used to integrate dynamic modeling of processes and static modeling of information structures. The results are unique in the sense that no other general event concept has been used to unify a similar broad variety of seemingly incompatible event concepts. The general event concept can be used...

  14. Periodic feedback stabilization for linear periodic evolution equations

    CERN Document Server

    Wang, Gengsheng

    2016-01-01

    This book introduces a number of recent advances regarding periodic feedback stabilization for linear and time periodic evolution equations. First, it presents selected connections between linear quadratic optimal control theory and feedback stabilization theory for linear periodic evolution equations. Secondly, it identifies several criteria for the periodic feedback stabilization from the perspective of geometry, algebra and analyses respectively. Next, it describes several ways to design periodic feedback laws. Lastly, the book introduces readers to key methods for designing the control machines. Given its coverage and scope, it offers a helpful guide for graduate students and researchers in the areas of control theory and applied mathematics.

  15. Testing Quantum Mechanics with Observations of Causally Disconnected Cosmological Events

    Science.gov (United States)

    Friedman, Andrew S.; Kaiser, D. I.; Gallicchio, J.; Guth, A. H.

    2014-01-01

    We discuss a thought experiment which would leverage cosmology to test quantum mechanics using astronomical observations. Specifically, we aim to close the "settings-independence" loophole in experimental tests of Bell's inequality by choosing the detector settings (e.g. polarizer orientations) using real-time observations of causally disconnected cosmic sources. This would help close one of the most important remaining Bell test loopholes whereby a local hidden variable theory could mimic the quantum predictions if the experimental settings choices shared even a small correlation due to unknown local causal influences prior to the experiment. The talk will focus on the theoretical cosmology constraints needed to choose optimal sources for such an experiment, describing general conditions for pairs of cosmic events with arbitrary redshifts and angular separations to have shared causal pasts in Friedman-Lemaitre-Robertson-Walker universes with arbitrary curvature, including flat, dark energy dominated, accelerating universes like our own. While causally disjoint patches of the cosmic microwave background radiation at redshift z ~ 1090 could be used to set the detectors, z > 3.65 quasars observed at optical wavelengths are arguably the optimal candidate source pairs using present technology that meet the condition of having no shared causal past since the end of any period of inflation, 13.82 Gyr ago. Results are illustrated for our universe with causal structure animations to help visualize the intersections of past light cones for arbitrary event pairs.

  16. A discrete-time multilevel mixture model for event history data with long-term survivors, with an application to an analysis of contraceptive sterilization in Bangladesh.

    Science.gov (United States)

    Steele, Fiona

    2003-06-01

    Event history models typically assume that the entire population is at risk of experiencing the event of interest throughout the observation period. However, there will often be individuals, referred to as long-term survivors, who may be considered a priori to have a zero hazard throughout the study period. In this paper, a discrete-time mixture model is proposed in which the probability of long-term survivorship and the timing of event occurrence are modelled jointly. Another feature of event history data that often needs to be considered is that they may come from a population with a hierarchical structure. For example, individuals may be nested within geographical regions and individuals in the same region may have similar risks of experiencing the event of interest due to unobserved regional characteristics. Thus, the discrete-time mixture model is extended to allow for clustering in the likelihood and timing of an event within regions. The model is further extended to allow for unobserved individual heterogeneity in the hazard of event occurrence. The proposed model is applied in an analysis of contraceptive sterilization in Bangladesh. The results show that a woman's religion and education level affect her probability of choosing sterilization, but not when she gets sterilized. There is also evidence of community-level variation in sterilization timing, but not in the probability of sterilization.

  17. 78 FR 55777 - Proposed Information Collection (VA, National Veterans Sports Programs and Special Events, Event...

    Science.gov (United States)

    2013-09-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS... correspondence. During the comment period, comments may be viewed online through FDMS. FOR FURTHER INFORMATION... Wheelchair Games Event Application, VA Form 0925b. f. Voluntary Service Application, VA Form 0925d. g...

  18. 76 FR 80312 - Periodic Reporting

    Science.gov (United States)

    2011-12-23

    ... Distribution Center (ADC) automation flats in First-Class Mail, Periodicals, and Standard Mail. Id. at 9-10... model for Periodicals flats. Currently, cells for the coverage of mechanized ADC pallet bundle sortation...

  19. 76 FR 8325 - Periodic Reporting

    Science.gov (United States)

    2011-02-14

    ... data for Presort First-Class Mail, and End-to-End Periodicals. Request at 1. The Request includes... Standard Mail, Outside County Periodicals, non-retail Media Mail, Library Mail, Bound Printed Matter...

  20. The redoubtable ecological periodic table

    Science.gov (United States)

    Ecological periodic tables are repositories of reliable information on quantitative, predictably recurring (periodic) habitat–community patterns and their uncertainty, scaling and transferability. Their reliability derives from their grounding in sound ecological principle...

  1. Event alignment, warping between running speeds

    DEFF Research Database (Denmark)

    Pontoppidan, Niels Henrik; Douglas, Ryan

    2004-01-01

    marine conditions (different load settings on the propeller curve) was in the range from 60 to 120 rotations per minute; furthermore the running speed was stable within periods of fixed load. Electronically controlled engines can change the angular timing of certain events, such as fuel injection...... the methods on data from the fuel injection period where the largest deviations in timing occur. The idea is that we, given aligned data, can use the already developed component analysis framework for non-stationary monitoring of condition changes. It should further be noticed that the proposed warp framework...

  2. Underwater noise due to precipitation

    DEFF Research Database (Denmark)

    Crum, Lawrence A.; Pumphrey, Hugh C.; Prosperetti, Andrea

    1989-01-01

    of this bubble resulted in a large amount of radiated sound. Recently, Scrimger has measured the underwater sound produced by rainfall and has discovered that a well-defined spectral peak exists near 15 kHz [J. A. Scrimger, Nature 318, 647 (1985)]. The sound produced by the impact of water droplets on a water......In 1959, G. Franz published a thorough investigation of the underwater sound produced by liquid drop impacts [G. Franz, J. Acoust. Soc. Am. 31, 1080 (1959)]. He discovered that, under certain conditions, a gas bubble was entrained by the impacting droplet, and the subsequent oscillation...... surface, both for individual and for multiple events such as those produced by artificial and natural rainfall, has been examined. The studies indicate that the major contribution to the underwater noise produced by both rain and snow is that associated with the oscillations of gas bubbles introduced...

  3. Spectral characteristics of the nearshore waves off Paradip, India during monsoon and extreme events

    Digital Repository Service at National Institute of Oceanography (India)

    Aboobacker, V.M.; Vethamony, P.; Sudheesh, K.; Rupali, S.P.

    and directional wave energy spectra distinctly separate out the wave conditions that prevailed off Paradip in the monsoon, fair weather and extreme weather events during the above period. Frequency-energy spectra during extreme events are single peaked...

  4. Autoerotic death due to electrocution

    Directory of Open Access Journals (Sweden)

    Piotr Arkuszewski

    2014-08-01

    Full Text Available Autoerotic death is a very rare case in forensic medicine. It is usually caused by asphyxia, but other reasons are also possible. Herein we present a case of autoerotic death due to electrocution caused by a self-made electrical device. The device was constructed to increase sexual feelings through stimulation of the scrotal area.

  5. Endocarditis due to Chryseobacterium meningosepticum

    Directory of Open Access Journals (Sweden)

    Bomb K

    2007-01-01

    Full Text Available Chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. It is known to cause meningitis in neonates and premature infants. Adult infections are not common and are usually nosocomially acquired. We report an unusual case of native valve endocarditis in a 58-year-old man due to this organism. A high degree of suspicion and correct identification and sensitivity testing is required to diagnose infections by this rare isolate.

  6. Parallel discrete event simulation

    NARCIS (Netherlands)

    Overeinder, B.J.; Hertzberger, L.O.; Sloot, P.M.A.; Withagen, W.J.

    1991-01-01

    In simulating applications for execution on specific computing systems, the simulation performance figures must be known in a short period of time. One basic approach to the problem of reducing the required simulation time is the exploitation of parallelism. However, in parallelizing the simulation

  7. Geneva Event (long version)

    CERN Multimedia

    CERN & BBC Open University

    1983-01-01

    Presentation of CERN at the time of the PSP. Carlo Rubbia presents his experiment on SPS, called UA1. He also deals with general aspects of the particle physics.The second part of the film deals with the beginnig of the first testing period of UA1, with the successfull result announced in January 1983

  8. Embryology, ethology and ecology of ontogenetic critical periods in fish.

    Science.gov (United States)

    Browman, H I

    1989-01-01

    Overviews of critical period concepts, as they appear at several biological levels, are presented. In embryology, critical periods generally refer to restricted periods in development during which undifferentiated groups of cells can be induced to differentiate. In neurobiology, critical periods are those during which neural circuits are particularly plastic and subject to molding by cellular processes and by experience. The ethological critical period concept advances the idea that an individual's behavioral characteristics can be more strongly influenced by a given event (some stimulus) at one stage of development than at others. For example, this is the period during which young birds imprint upon their parent(s) and learn their species' songs, or during which young salmon imprint to the odor of their home streams. The fisheries science critical period, an ecological concept, refers to a restricted time in the early life history of fish during which there is massive mortality. For many fish, this event is generally considered the primary factor controlling the size of the adult population. The cause of variable mortality between years is thought to be a result of differential food availability and predation during a critical stage in early fish larval development. At each biological level of the critical period, spatial and temporal overlap between the developing organism and specific environmental input is essential. It is likely that critical periods in embryology, neurobiology and ethology are causally interrelated in a hierarchical manner and that they can be manifested as ecological critical periods.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. Using satellite data for forecasting radiation hazards due to great SEP events

    Science.gov (United States)

    Lev, Dorman; Zukerman, Igor; Pustilnik, Lev; Dai, Uri; Shternlib, Abracham; Shai Applbaum, David; Kazantsev, Vasilii; Ben Israel, Isaac; Fatima, Keshtova

    The model is based on one minute satellite data (e.g., from the GOES series) available on the Internet in different energy ranges (from 4 MeV up to 500 MeV). First, we developed a program that automatically determines the beginning of an SEP by continuously analysing satellite data After the start of an SEP, we determine the SEP energy spectrum by using data in the four largest energy ranges. After a few (at least 4) minutes, we try to solve the inverse problem of SEP generation and propagation and estimate on the basis of determined changes of SEP energy spectrum in time the following main parameters: time of ejection into solar wind, energy spectrum of SEP generation, two-parametric diffusion coefficient in dependence of energy and distance from the Sun. With each new minute of observation obtained results of the inverse problem solution became more and more exactly. For each new minute of observation we then solve direct problem (by using estimated values of time of ejection into solar wind, energy spectrum of SEP generation, two-parametric diffusion coefficient) and determine expected SEP fluxes in different energy ranges not only during observed time (for checking solution of inverse problem), but also expected SEP fluxes in near future for forecasting of expected total radiation hazard in space, in magnetosphere, and in atmosphere for spacecrafts, satellites, and airplanes.

  10. 28. INCREASED LIKELIHOOD OF BRISBANE, AUSTRALIA, G20 HEAT EVENT DUE TO ANTHROPOGENIC CLIMATE CHANGE

    National Research Council Canada - National Science Library

    Andrew D King; Mitchell T Black; David J Karoly; Markus G Donat

    2015-01-01

    ...., uncertainties related to model set-up) in our attribution statement, the FAR calculations were performed separately using each natural forcing subensemble where SSTs were derived from ten global climate models (GCMs...

  11. Simulating Damage Due to a Lightning Strike Event: Effects of Temperature Dependent Properties on Interlaminar Damage

    Science.gov (United States)

    Ghezeljeh, Paria Naghipour; Pineda, Evan Jorge

    2014-01-01

    A multidirectional, carbon fiber-epoxy, composite panel is subjected to a simulated lightning strike, within a finite element method framework, and the effect of material properties on the failure (delamination) response is investigated through a detailed numerical study. The numerical model of the composite panel consists of individual homogenized plies with user-defined, cohesive interface elements between them. Lightning strikes are simulated as an assumed combination of excessive heat and high pressure loadings. It is observed that the initiation and propagation of lightning-induced delamination is a significant function of the temperature dependency of interfacial fracture toughness. This dependency must be defined properly in order to achieve reliable predictions of the present lightning-induced delamination in the composite panel.

  12. Underestimating extreme events in power-law behavior due to machine-dependent cutoffs

    Science.gov (United States)

    Radicchi, Filippo

    2014-11-01

    Power-law distributions are typical macroscopic features occurring in almost all complex systems observable in nature. As a result, researchers in quantitative analyses must often generate random synthetic variates obeying power-law distributions. The task is usually performed through standard methods that map uniform random variates into the desired probability space. Whereas all these algorithms are theoretically solid, in this paper we show that they are subject to severe machine-dependent limitations. As a result, two dramatic consequences arise: (i) the sampling in the tail of the distribution is not random but deterministic; (ii) the moments of the sample distribution, which are theoretically expected to diverge as functions of the sample sizes, converge instead to finite values. We provide quantitative indications for the range of distribution parameters that can be safely handled by standard libraries used in computational analyses. Whereas our findings indicate possible reinterpretations of numerical results obtained through flawed sampling methodologies, they also pave the way for the search for a concrete solution to this central issue shared by all quantitative sciences dealing with complexity.

  13. The Astronomical Pulse of Global Extinction Events

    Directory of Open Access Journals (Sweden)

    David F.V. Lewis

    2006-01-01

    Full Text Available The linkage between astronomical cycles and the periodicity of mass extinctions is reviewed and discussed. In particular, the apparent 26 million year cycle of global extinctions may be related to the motion of the solar system around the galaxy, especially perpendicular to the galactic plane. The potential relevance of Milankovitch cycles is also explored in the light of current evidence for the possible causes of extinction events over a geological timescale.

  14. Detection of solar events

    Science.gov (United States)

    Fischbach, Ephraim; Jenkins, Jere

    2013-08-27

    A flux detection apparatus can include a radioactive sample having a decay rate capable of changing in response to interaction with a first particle or a field, and a detector associated with the radioactive sample. The detector is responsive to a second particle or radiation formed by decay of the radioactive sample. The rate of decay of the radioactive sample can be correlated to flux of the first particle or the field. Detection of the first particle or the field can provide an early warning for an impending solar event.

  15. CATASTROPHIC EVENTS MODELING

    Directory of Open Access Journals (Sweden)

    Ciumas Cristina

    2013-07-01

    Full Text Available This paper presents the emergence and evolution of catastrophe models (cat models. Starting with the present context of extreme weather events and features of catastrophic risk (cat risk we’ll make a chronological illustration from a theoretical point of view of the main steps taken for building such models. In this way the importance of interdisciplinary can be observed. The first cat model considered contains three modules. For each of these indentified modules: hazard, vulnerability and financial losses a detailed overview and also an exemplification of a potential case of an earthquake that measures more than 7 on Richter scale occurring nowadays in Bucharest will be provided. The key areas exposed to earthquake in Romania will be identified. Then, based on past catastrophe data and taking into account present conditions of housing stock, insurance coverage and the population of Bucharest the impact will be quantified by determining potential losses. In order to accomplish this work we consider a scenario with data representing average values for: dwelling’s surface, location, finishing works. On each step we’ll make a reference to the earthquake on March 4 1977 to see what would happen today if a similar event occurred. The value of Bucharest housing stock will be determined taking firstly the market value, then the replacement value and ultimately the real value to quantify potential damages. Through this approach we can find the insurance coverage of potential losses and also the uncovered gap. A solution that may be taken into account by public authorities, for example by Bucharest City Hall will be offered: in case such an event occurs the impossibility of paying compensations to insured people, rebuilding infrastructure and public buildings and helping the suffering persons should be avoided. An actively public-private partnership should be created between government authorities, the Natural Disaster Insurance Pool, private

  16. Did the 8.2 ka event affect southern Africa?

    Science.gov (United States)

    Shaw, Paul

    2014-05-01

    Palaeoenvironmental reconstruction of southern Africa over the past 4 decades has focused largely on the last glacial cycle, and, more recently, events during to Holocene, interpreted largely at the millennial scale. Little attention has been given to sub-millenial drivers and impacts, other than the Little Ice Age (HolmgreN et al 2001). The 8.2ka event has been recognized in Europe for over half a century from peat cores and dendrochronology. A Bond Event caused by disruption of the Gulf Stream by melting Laurentian ice, it lasted around 100 years and resulted in a fall in temperature in northern Europe of up to 6o C. Recently published high-resolution speleothem records have indicated significant short-term change over a much wider area than previously thought, including the Caribbean, eastern Brazil, Spain, Oman and China. A recent paper on Trinidad (Boyd et al, in press) emphasizes a period of prolonged drought in the southern Caribbean due to a southerly emplacement of the ITCZ. The question then arises whether this shift affected the southern hemisphere, and if so, what would be the likely impacts and evidence. A study of late Quaternary lake levels in Lake Chilwa, Malawi (Thomas et al 2009) noted a correspondence between high lake stands and Heinrich events, whilst modeling of Atlantic freshwater influx using the HadCM3 GCM indicates negative precipitation anomalies in the Caribbean and west Africa, with a significant positive anomaly in the interior of southern Africa, possibly linked to enhanced monsoonal activity in the Indian Ocean. These patterns in southern and western Africa have been suggested around 8.2 ka in a review of early Holocene data (Burrough & Thomas 2013), but the chronological resolution is not sufficient to conclude the observation. The only speleothem record for this period, T8 in Cold Air Cave, Makapansgat Valley (Holmgren et al 2003) shows an anomaly, but with temporal resolution at a 50 yr sampling interval, this again is speculative

  17. Asynchronous presynaptic glutamate release enhances neuronal excitability during the post-spike refractory period.

    Science.gov (United States)

    Iremonger, Karl J; Bains, Jaideep S

    2016-02-15

    Many excitatory synapses in the brain release glutamate with both synchronous and asynchronous components. Immediately following an action potential, neurons display a reduced excitability due to the post-spike afterhyperpolarization (AHP). This gives rise to a relative refractory period. When an action potential is evoked by glutamate synaptic input possessing asynchronous release, the delayed glutamate release events act to depolarize the neuron during the AHP and overcome the relative refractory period. These results demonstrate a new role for asynchronous release in regulating post-spike excitability and the relative refractory period in central neurons. Post-spike afterhyperpolarizations (AHPs) functionally inhibit neuronal excitability for tens to hundreds of milliseconds following each action potential. This imposes a relative refractory period during which synaptic excitation is less effective at evoking spikes. Here we asked whether some synapses have mechanisms in place that allow them to overcome the AHP and drive spiking in target cells during this period of reduced excitability. We examined glutamate synapses onto oxytocin and vasopressin neurons in the paraventricular nucleus of the hypothalamus. These synapses can display pronounced asynchronous glutamate release following a single presynaptic spike, with the time course of release being similar to that of the post-spike AHP. To test whether asynchronous release is more effective at overcoming the relative refractory period, we evoked a single action potential with either a brief synchronous depolarization or an asynchronous potential and then assessed excitability at multiple time points following the spike. Neurons receiving asynchronous depolarizing synaptic inputs had a shorter relative refractory period than those receiving synchronous depolarizations. Our data demonstrate that synapses releasing glutamate in an asynchronous and delayed manner are ideally adapted to counter the AHP. By

  18. State-based Event Detection Optimization for Complex Event Processing

    Directory of Open Access Journals (Sweden)

    Shanglian PENG

    2014-02-01

    Full Text Available Detection of patterns in high speed, large volume of event streams has been an important paradigm in many application areas of Complex Event Processing (CEP including security monitoring, financial markets analysis and health-care monitoring. To assure real-time responsive complex pattern detection over high volume and speed event streams, efficient event detection techniques have to be designed. Unfortunately evaluation of the Nondeterministic Finite Automaton (NFA based event detection model mainly considers single event query and its optimization. In this paper, we propose multiple event queries evaluation on event streams. In particular, we consider scalable multiple event detection model that shares NFA transfer states of different event queries. For each event query, the event query is parse into NFA and states of the NFA are partitioned into different units. With this partition, the same individual state of NFA is run on different processing nodes, providing states sharing and reducing partial matches maintenance. We compare our state-based approach with Stream-based And Shared Event processing (SASE. Our experiments demonstrate that state-based approach outperforms SASE both on CPU time usage and memory consumption.

  19. Testing the sensitivity of trade linkages in Europe to compound drought events

    Science.gov (United States)

    Veldkamp, Ted; Koks, Elco; Thissen, Mark; Wahl, Thomas; Haigh, Ivan; Muis, Sanne; Ward, Philip

    2017-04-01

    Droughts can be defined as spatially extensive events that are characterized by temporal deficits in precipitation, soil moisture or streamflow, and have the potential to cause large direct and indirect economic losses. Many European countries face drought as an economically important hazard, with agriculture, livestock, forestry, energy, industry, and water sectors particularly at risk, causing economic losses of 139 billion US over the past 30 years. Apart from these direct impacts, business production and the flow of goods and services can be affected indirectly by droughts. With consequences that can propagate through the economic system affecting regions not directly hit by the drought event itself, or in time-periods long after the original drought event occurred. In this study, we evaluate the sensitivity of existing trade linkages between the different NUTS-2 regions in Europe to the coupled occurrence of hydro-meteorological drought events, and their associated production losses. Using a multi-regional supply-use model for Europe, we have, on a product level, insight in the existing trade linkages between NUTS-2 regions. Using this information in combination with historical drought data, we assessed and identified for a selection of water related products: 1) the dependency-structures of the NUTS-2 regions within Europe for the import and export of products (and therein water); 2) the coupled nature of drought events occurring in regions that are linked via these trade-patterns; 3) the probability of not meeting demands (on a product level) due to drought events and the associated (indirect economic) impacts; and 4) regions that lose or benefit from their selection of trade-partners given the coupled nature of drought events, as well as the net effects for Europe as a whole.

  20. THE ROLE AND IMPLICATIONS OF THE EVENT BASED COMMUNICATION IN THE ELECTORAL CAMPAIGN

    Directory of Open Access Journals (Sweden)

    Tatu Cristian Ionut

    2011-12-01

    Full Text Available The electoral campaigns are considered to be among the most delicate challenges for a marketer due to the limited time available, the sensible margin for error, the high impact of each statement and the condensation of a quite large amount of resources in a 30 day period. While the ultimate goal for the campaign staff is to bring the global electoral package closer to the electorate and earn their votes most, of the time various competitors use disappointingly similar tactics that create confusion among the electorate. The campaign related events turned out to be one of the tactics that allows for a pin-point targeting of the electorate and a better control on the receivers of the message. This paper focuses on the types of events used that can be used in an electoral campaign reinforced with their particularities and effects registered in previous campaigns.

  1. Relativistic tidal disruption events

    Directory of Open Access Journals (Sweden)

    Levan A.

    2012-12-01

    Full Text Available In March 2011 Swift detected an extremely luminous and long-lived outburst from the nucleus of an otherwise quiescent, low luminosity (LMC-like galaxy. Named Swift J1644+57, its combination of high-energy luminosity (1048 ergs s−1 at peak, rapid X-ray variability (factors of >100 on timescales of 100 seconds and luminous, rising radio emission suggested that we were witnessing the birth of a moderately relativistic jet (Γ ∼ 2 − 5, created when a star is tidally disrupted by the supermassive black hole in the centre of the galaxy. A second event, Swift J2058+0516, detected two months later, with broadly similar properties lends further weight to this interpretation. Taken together this suggests that a fraction of tidal disruption events do indeed create relativistic outflows, demonstrates their detectability, and also implies that low mass galaxies can host massive black holes. Here, I briefly outline the observational properties of these relativistic tidal flares observed last year, and their evolution over the first year since their discovery.

  2. SMOS data and extreme events

    Science.gov (United States)

    Kerr, Yann; Wigneron, Jean-Pierre; Ferrazzoli, Paolo; Mahmoodi, Ali; Al-Yaari, Amen; Parrens, Marie; Bitar, Ahmad Al; Rodriguez-Fernandez, Nemesio; Bircher, Simone; Molero-rodenas, Beatriz; Drusch, Matthias; Mecklenburg, Susanne

    2017-04-01

    The SMOS (Soil Moisture and Ocean Salinity) satellite was successfully launched in November 2009. This ESA led mission for Earth Observation is dedicated to provide soil moisture over continental surface (with an accuracy goal of 0.04 m3/m3), vegetation water content over land, and ocean salinity. These geophysical features are important as they control the energy balance between the surface and the atmosphere. Their knowledge at a global scale is of interest for climatic and weather researches, and in particular in improving model forecasts. The Soil Moisture and Ocean Salinity mission has now been collecting data for over 7 years. The whole data set has been reprocessed (Version 620 for levels 1 and 2 and version 3 for level 3 CATDS) while operational near real time soil moisture data is now available and assimilation of SMOS data in NWP has proved successful. After 7 years it seems important to start using data for having a look at anomalies and see how they can relate to large scale events. We have also produced a 15 year soil moisture data set by merging SMOS and AMSR using a neural network approach. The purpose of this communication is to present the mission results after more than seven years in orbit in a climatic trend perspective, as through such a period anomalies can be detected. Thereby we benefit from consistent datasets provided through the latest reprocessing using most recent algorithm enhancements. Using the above mentioned products it is possible to follow large events such as the evolution of the droughts in North America, or water fraction evolution over the Amazonian basin. In this occasion we will focus on the analysis of SMOS and ancillary products anomalies to reveal two climatic trends, the temporal evolution of water storage over the Indian continent in relation to rainfall anomalies, and the global impact of El Nino types of events on the general water storage distribution. This presentation shows in detail the use of long term data sets

  3. Electromagnetic Radiation of Electrons in Periodic Structures

    CERN Document Server

    Potylitsyn, Alexander Petrovich

    2011-01-01

    Periodic magnetic structures (undulators) are widely used in accelerators to generate monochromatic undulator radiation (UR) in the range from far infrared to the hard X-ray region. Another periodic crystalline structure is used to produce quasimonochromatic polarized photon beams via the coherent bremsstrahlung mechanism (CBS). Due to such characteristics as monochromaticity, polarization and adjustability, these types of radiation is of large interest for applied and basic research of accelerator-emitted radiation. The book provides a detailed overview of the fundamental principles behind electromagnetic radiation emitted from accelerated charged particles (e.g. UR, CBS, radiation of fast electrons in Laser flash fields) as well as a unified description of relatively new radiation mechanisms which attracted great interest in recent years. This are the so-called polarization radiation excited by the Coulomb field of incident particles in periodic structures, parametric X-rays, resonant transition radiation a...

  4. Nonparametric Inference for Periodic Sequences

    KAUST Repository

    Sun, Ying

    2012-02-01

    This article proposes a nonparametric method for estimating the period and values of a periodic sequence when the data are evenly spaced in time. The period is estimated by a "leave-out-one-cycle" version of cross-validation (CV) and complements the periodogram, a widely used tool for period estimation. The CV method is computationally simple and implicitly penalizes multiples of the smallest period, leading to a "virtually" consistent estimator of integer periods. This estimator is investigated both theoretically and by simulation.We also propose a nonparametric test of the null hypothesis that the data have constantmean against the alternative that the sequence of means is periodic. Finally, our methodology is demonstrated on three well-known time series: the sunspots and lynx trapping data, and the El Niño series of sea surface temperatures. © 2012 American Statistical Association and the American Society for Quality.

  5. Event Shape Sorting: selecting events with similar evolution

    Directory of Open Access Journals (Sweden)

    Tomášik Boris

    2017-01-01

    Full Text Available We present novel method for the organisation of events. The method is based on comparing event-by-event histograms of a chosen quantity Q that is measured for each particle in every event. The events are organised in such a way that those with similar shape of the Q-histograms end-up placed close to each other. We apply the method on histograms of azimuthal angle of the produced hadrons in ultrarelativsitic nuclear collisions. By selecting events with similar azimuthal shape of their hadron distribution one chooses events which are likely that they underwent similar evolution from the initial state to the freeze-out. Such events can more easily be compared to theoretical simulations where all conditions can be controlled. We illustrate the method on data simulated by the AMPT model.

  6. [Influence of armed conflict on mortality due to traumatic brain injury in children and adolescents].

    Science.gov (United States)

    Alcalá-Cerra, Gabriel; Paternina-Caicedo, Ángel; Palacio-Babilonia, Betty; Moscote-Salazar, Luis Rafael; Niño-Hernández, Lucía M; Gutiérrez-Paternina, Juan José

    2014-01-01

    In the presence an armed conflagration, the mortality behavior of a country is expected to be affected. The aim of this investigation was to assess, in a country with internal warfare, the trend of mortality associated with traumatic brain injury in children and adolescents, which even under social peace conditions, is one of the most common causes of death and disability in this population groups. A retrospective, population-based study was conducted, where the trend of mortality due to traumatic brain injury during the 1999 to 2008 period was assessed. A linear regression was performed to establish its correlation with mortality associated with warfare events of the armed conflict. Global mortality rate was 12.7 per 100 000 inhabitants. The temporary analysis showed a -9.67% annual decrease throughout the entire period of study (95 % CI = -9.25 % to -10.1 %; p conflict-related violent death rate and in civilian population, respectively. In an armed conflict scenario, mortality behavior varies according to the intensity of warfare actions. Mortality due to traumatic brain injury in children and adolescents can be used as an indicator of the impact of war on civilian population not involved with the armed conflict.

  7. Maculopathy due to drug inhalation.

    Science.gov (United States)

    Asensio-Sánchez, V M; Gonzalez-Buendia, L; Marcos-Fernández, M

    2014-08-01

    A case of maculopathy due to "poppers" is described. Poppers is a drug composed of various forms of alkyl nitrite. A 39 year-old man, who had been using poppers for years, was seen in the clinic with phosphenes, reduced visual acuity and central scotoma. The SD-OCT in the right eye showed disruption at the level of the IS/OS junction line. The SD-OCT scan in the left eye showed an outer rectangular retinal hole and an outer retinal cyst. Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  8. Polar cap absorption events of November 2001 at Terra Nova Bay, Antarctica

    Directory of Open Access Journals (Sweden)

    L. Perrone

    2004-04-01

    Full Text Available Polar cap absorption (PCA events recorded during November 2001 are investigated by observations of ionospheric absorption of a 30MHz riometer installed at Terra Nova Bay (Antarctica, and of solar proton flux, monitored by the NOAA-GOES8 satellite in geo-synchronous orbit. During this period three solar proton events (SPE on 4, 19 and 23 November occurred. Two of these are among the dozen most intense events since 1954 and during the current solar cycle (23rd, the event of 4 November shows the greatest proton flux at energies >10MeV. Many factors contribute to the peak intensity of the two SPE biggest events, one is the Coronal Mass Ejection (CME speed, other factors are the ambient population of SPE and the shock front due to the CME. During these events absorption peaks of several dB (~20dB are observed at Terra Nova Bay, tens of minutes after the impact of fast halo CMEs on the geomagnetic field.

    Results of a cross-correlation analysis show that the first hour of absorption is mainly produced by 84–500MeV protons in the case of the 4 November event and by 15–44MeV protons for the event of 23 November, whereas in the entire event the contribution to the absorption is due chiefly to 4.2–82MeV (4 November and by 4.2–14.5MeV (23 November. Good agreement is generally obtained between observed and calculated absorption by the empirical flux-absorption relationship for threshold energy E0=10MeV. From the residuals one can argue that other factors (e.g. X-ray increases and geomagnetic disturbances can contribute to the ionospheric absorption.

    Key words. Ionosphere (Polar Ionosphere, Particle precipitation – Solar physics (Flares and mass ejections

  9. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Zoom into the tracking detector. Muon tracks are colored red.

  10. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Muon tracks are colored red.

  11. Reflex anuria following acute cardiac event.

    Science.gov (United States)

    Jeevagan, Vijayabala; Navinan, Mitrakrishnan; Munasinghe, Arunie; Nazar, Abdul; Wijewardena, Anura; Constantine, Godwin

    2013-05-20

    Reflex anuria is an uncommon cause for acute renal failure, which occurs almost always after manipulation or irritation to kidneys, ureter, bladder or other pelvic organs. Here we describe a case of acute renal failure due to reflex anuria following acute cardiac event. This patient had background history of urolithiasis. In the absence of other pre renal, renal or post- renal causes for acute kidney injury, we believe reflex anuria is the causative entity for acute renal failure in our patient. Acute renal failure due to reflex anuria is related to a reflex mechanism involving arteriolar vasoconstriction and urethral spasm. Patients with reflex anuria can be successfully managed with medical or surgical interventions. Our case suggests that reflex anuria should be considered as one of the differential diagnosis of acute renal failure following acute cardiac event, especially in patients with background urological problem.

  12. Young adolescents' identification of difficult life events.

    Science.gov (United States)

    Riesch, S K; Jacobson, G A; Tosi, C B

    1994-11-01

    As part of a larger study of parent-child communication, young adolescents (n = 847), aged 11 to 14 years, responded with brief written answers to the question: "Using your own words, list any happenings that occurred in the family that you feel may have been difficult and have long-lasting effects." The sample was chiefly seventh- and eighth-grade students from two-parent, White, middle-class, urban homes. Content analyses of their responses resulted in the following themes: feelings of loss due to death, divorce, relocation, or a sibling leaving the family; feelings of threat toward family relationships or integrity, personal or family health, personal or family safety and well-being, and violence; feelings of being hassled due to parents' expectations and limits and siblings' disagreements and conflicts; and testing maturity. The data provide significant examples of the life events of families. Recommendations to identify and care for families and young adolescents experiencing these events are proposed.

  13. Cellulitis Due to Salmonella infantis.

    Directory of Open Access Journals (Sweden)

    Satish R Patil

    2013-01-01

    Full Text Available Bacteria of the genus Salmonella are highly adapted for the growth in both humans and animals and cause a wide spectrum of disease. The growth of Serotypes S. typhi and S. paratyphi is restricted to human hosts, in whom these organisms cause enteric (typhoid fever. The remaining Serotypes (non typhoidal Salmonella or NTS can colonize the gastrointestinal tracts of the broad range of animals, including mammals, reptiles, birds and insects. The usual clinical presentation of non-typhoidal salmonellae (NTS infection is self limited gastroenteritis; however bacteremia and focal extra intestinal infection may occur. However salmonella localization to the skin presenting as cutaneous ulceration is regarded as a rare event. Rates of morbidity and mortality associated with NTS are highest among the elderly, infants, and immunocompromised individuals, including those with hemoglobinopathies, HIV infection, or infections that cause blockade of the reticuloendothelial system. We isolated S.infantis in 50 years old man with left leg cellulitis. The serotype was confirmed at Central Research Institute, Kasauli.

  14. Periodicity of DNA in exons

    Directory of Open Access Journals (Sweden)

    Kinghorn Brian

    2004-08-01

    Full Text Available Abstract Background The periodic pattern of DNA in exons is a known phenomenon. It was suggested that one of the initial causes of periodicity could be the universal (RNYnpattern (R = A or G, Y = C or U, N = any base of ancient RNA. Two major questions were addressed in this paper. Firstly, the cause of DNA periodicity, which was investigated by comparisons between real and simulated coding sequences. Secondly, quantification of DNA periodicity was made using an evolutionary algorithm, which was not previously used for such purposes. Results We have shown that simulated coding sequences, which were composed using codon usage frequencies only, demonstrate DNA periodicity very similar to the observed in real exons. It was also found that DNA periodicity disappears in the simulated sequences, when the frequencies of codons become equal. Frequencies of the nucleotides (and the dinucleotide AG at each location along phase 0 exons were calculated for C. elegans, D. melanogaster and H. sapiens. Two models were used to fit these data, with the key objective of describing periodicity. Both of the models showed that the best-fit curves closely matched the actual data points. The first dynamic period determination model consistently generated a value, which was very close to the period equal to 3 nucleotides. The second fixed period model, as expected, kept the period exactly equal to 3 and did not detract from its goodness of fit. Conclusions Conclusion can be drawn that DNA periodicity in exons is determined by codon usage frequencies. It is essential to differentiate between DNA periodicity itself, and the length of the period equal to 3. Periodicity itself is a result of certain combinations of codons with different frequencies typical for a species. The length of period equal to 3, instead, is caused by the triplet nature of genetic code. The models and evolutionary algorithm used for characterising DNA periodicity are proven to be an effective tool

  15. The dual effect of vegetation green-up date and strong wind on the return period of spring dust storms.

    Science.gov (United States)

    Feng, Jieling; Li, Ning; Zhang, Zhengtao; Chen, Xi

    2017-08-15

    Vegetation phenology changes have been widely applied in the disaster risk assessments of the spring dust storms, and vegetation green-up date shifts have a strong influence on dust storms. However, the effect of earlier vegetation green-up dates due to climate warming on the evaluation of dust storms return periods remains an important, but poorly understood issue. In this study, we evaluate the spring dust storm return period (February to June) in Inner Mongolia, Northern China, using 165 observations of severe spring dust storm events from 16 weather stations, and regional vegetation green-up dates as an integrated factor from NDVI (Normalized Difference Vegetation Index), covering a period from 1982 to 2007, by building the bivariate Copula model. We found that the joint return period showed better fitting results than without considering the integrated factor when the actual dust storm return period is longer than 2years. Also, for extremely severe dust storm events, the gap between simulation result and actual return period can be narrowed up to 0.4888years by using integrated factor. Furthermore, the risk map based on the return period results shows that the Mandula, Zhurihe, Sunitezuoqi, Narenbaolige stations are identified as high risk areas. In this study area, land surface is extensively covered by grasses and shrubs, vegetation green-up date can play a significant role in restraining spring dust storm outbreaks. Therefore, we suggest that Copula method can become a useful tool for joint return period evaluation and risk analysis of severe dust storms. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Uncovering undetected hypoglycemic events

    Directory of Open Access Journals (Sweden)

    Unger J

    2012-03-01

    Full Text Available Jeff UngerCatalina Research Institute, Chino, CA, USAAbstract: Hypoglycemia is the rate-limiting factor that often prevents patients with diabetes from safely and effectively achieving their glycemic goals. Recent studies have reported that severe hypoglycemia is associated with a significant increase in the adjusted risks of major macrovascular events, major microvascular events, and mortality. Minor hypoglycemic episodes can also have serious implications for patient health, psychological well being, and adherence to treatment regimens. Hypoglycemic events can impact the health economics of the patient, their employer, and third-party payers. Insulin treatment is a key predictor of hypoglycemia, with one large population-based study reporting an overall prevalence of 7.1% (type 1 diabetes mellitus and 7.3% (type 2 diabetes mellitus in insulin-treated patients, compared with 0.8% in patients with type 2 diabetes treated with an oral sulfonylurea. Patients with type 1 diabetes typically experience symptomatic hypoglycemia on average twice weekly and severe hypoglycemia once annually. The progressive loss of islet cell function in patients with type 2 diabetes results in a higher risk of both symptomatic and unrecognized hypoglycemia over time. Patients with diabetes who become hypoglycemic are also more susceptible to developing defective counter-regulation, also known as hypoglycemia awareness autonomic failure, which is life-threatening and must be aggressively addressed. In patients unable to recognize hypoglycemia symptoms, frequent home monitoring or use of continuous glucose sensors are critical. Primary care physicians play a key role in the prevention and management of hypoglycemia in patients with diabetes, particularly in those requiring intensive insulin therapy, yet physicians are often unaware of the multitude of consequences of hypoglycemia or how to deal with them. Careful monitoring, adherence to guidelines, and use of optimal

  17. Event-by-event simulation of quantum phenomena

    NARCIS (Netherlands)

    Raedt, H. De; Raedt, K. De; Michielsen, K.; Landau, DP; Lewis, SP; Schuttler, HB

    2006-01-01

    In various basic experiments in quantum physics, observations are recorded event-by-event. The final outcome of such experiments can be computed according to the rules of quantum theory but quantum theory does not describe single events. In this paper, we describe a stimulation approach that does

  18. Event Segmentation Improves Event Memory up to One Month Later

    Science.gov (United States)

    Flores, Shaney; Bailey, Heather R.; Eisenberg, Michelle L.; Zacks, Jeffrey M.

    2017-01-01

    When people observe everyday activity, they spontaneously parse it into discrete meaningful events. Individuals who segment activity in a more normative fashion show better subsequent memory for the events. If segmenting events effectively leads to better memory, does asking people to attend to segmentation improve subsequent memory? To answer…

  19. Analysis of Future Event Set Algorithms for Discrete Event Simulation

    OpenAIRE

    McCormack, William M.; Sargent, Robert G.

    1980-01-01

    This work reports on new analytical and empirical results on the performance of algorithms for handling the future event set in discrete event simulation. These results provide a clear insight to the factors affecting algorithm performance; evaluate the "hold" model, often used to study future event set algorithms; and determine the best algorithm(s) to use.

  20. Event by event method for quantum interference simulation

    NARCIS (Netherlands)

    Mutia Delina, M

    2014-01-01

    Event by event method is a simulation approach which is not based on the knowledge of the Schrödinger equation. This approach uses the classical wave theory and particle concept: we use particles, not waves. The data is obtained by counting the events that were detected by the detector, just as in

  1. Purchase decision involvement: Event management segments and related event behavior

    Science.gov (United States)

    Rodney B. Warnick; David C. Bojanic

    2012-01-01

    The goal of this research was to examine the relationships between different levels of event purchase decision involvement (PDI) segments and their respective event behaviors (e.g., expenditures, travel behavior, event consumption and satisfaction). The specific purpose was to answer two major research questions: 1) Can PDI identify different levels or segments of...

  2. Extreme events in the forced Liénard system

    Science.gov (United States)

    Kingston, S. Leo; Thamilmaran, K.; Pal, Pinaki; Feudel, Ulrike; Dana, Syamal K.

    2017-11-01

    We observe extremely large amplitude intermittent spikings in a dynamical variable of a periodically forced Liénard-type oscillator and characterize them as extreme events, which are rare, but recurrent and larger in amplitude than a threshold. The extreme events occur via two processes, an interior crisis and intermittency. The probability of occurrence of the events shows a long-tail distribution in both the cases. We provide evidence of the extreme events in an experiment using an electronic analog circuit of the Liénard oscillator that shows good agreement with our numerical results.

  3. Ion production and ionization effect in the atmosphere during the Bastille day GLE 59 due to high energy SEPs

    Science.gov (United States)

    Mishev, A. L.; Velinov, P. I. Y.

    2018-01-01

    The influence of high energy particles, specifically cosmic rays, on atmospheric physics and chemistry is highly discussed. In most of the proposed models the role of ionization in the atmosphere due to cosmic rays is not negligible. Moreover, effect(s) on minor constituents and aerosols are recently observed, specifically over the polar regions during strong solar particle events. According to the recent findings for such effects it is necessary an essential increase of ion production, specifically during the winter period. The galactic cosmic rays are the main source of ionization in the Earth's stratosphere and troposphere. Occasionally, the atmospheric ionization is significantly enhanced during strong solar energetic particles events, specifically over the polar caps. During the solar cycle 23 several strong ground level enhancements were observed. One of the strongest was the Bastille day event occurred on 14 July 2000. Using a full Monte Carlo 3-D model, we compute the atmospheric ionization, considering explicitly the contribution of cosmic rays with galactic and solar origin, focusing on high energy particles. The model is based on atmospheric cascade simulation with the PLANETOCOSMICS code. The ion production rate is computed as a function of the altitude above the sea level. The ion production rate is computed on a step ranging from 10 to 30 min throughout the event, considering explicitly the spectral and angular characteristics of the high energy part of solar protons as well as their time evolution. The corresponding event averaged ionization effect relative to the average due to galactic cosmic rays is computed in lower stratosphere and upper troposphere at various altitudes, namely 20 km, 15 km, 12 km and 8 km above the sea level in a sub-polar and polar regions. The 24h and the weekly ionization effects are also computed in the troposphere and low stratosphere. Several applications are discussed.

  4. Leg ulcers due to hyperhomocysteinemia

    Directory of Open Access Journals (Sweden)

    Krupa Shankar D

    2006-01-01

    Full Text Available Chronic leg ulcers are rare in young adults and generally indicate a vascular cause. We report a case of a 26-year-old man with leg ulcers of eight months duration. Doppler study indicated venous incompetence and a postphlebitic limb. However, as the distribution and number of ulcers was not consistent with stasis alone and no features of collagen vascular disease were noted, a hyperviscosity state was considered and confirmed with significantly elevated homocysteine level in the serum. Administration of vitamins B1, B2, B6 and B12, trimethyl-glycine, mecobalamine, folic acid and povidone iodine dressings with culture-directed antibiotic therapy led to a satisfactory healing of ulcers over a period of one month. Hyperhomocysteinemia must be considered in the differential diagnosis of leg ulcers in young individuals.

  5. Present El Niño-ENSO events and past Super-ENSO events

    Directory of Open Access Journals (Sweden)

    1993-01-01

    hidrosfera. Los actuales eventos El Niño-ENSO muestran una clara correlación con deceleraciones interanuales de la velocidad de rotación de la Tierra: la duración del día (LOD aumenta. Aunque generalmente se sostiene que estos cambios rotacionales son causados por intercambio de momento angular con la atmósfera, aquí mostramos que gran parte, tal vez la mayor parte, de las variaciones del LOD son en realidad causadas por el intercambio de momento angular entre la Tierra “sólida” y la hidrosfera en un sistema acoplado de regeneración. Este mecanismo también actúa en escalas de tiempo decadal a secular dando lugar a eventos Super-ENSO. Varios de estos eventos se han identificado en el Holoceno. Un evento mayor ocurrió en la era medieval. En el período de 13.5 a 9.5 Ka, los cambios de gran altitud pueden representar eventos de Mega-ENSO. Durante las edades glaciales, con una velocidad de rotación mucho mayor, se piensa que los eventos ENSO-EL Niño debieron estar ausentes. EN los registros del pasado, de corto término, las imprentas de eventos Super-ENSO deben ser mucho más frecuentes que aquellas de verdaderos ENSO interanuales, simplemente porque estos últimos son demasiado breves y usualmente demasiado leves. Present ENSO events and past Super-ENSO events represent the redistribution of energy and mass within the terrestrial system due to the interchange of angular momentum between the “solid” Earth and the hydrosphere. The present El Niño-ENSO events exhibit clear correlations with interannual decelerations in the Earth’s rate of rotation the length-of-day (LOD increases. Though it is generally claimed that theses rotational changes are caused by the interchange of angular momentum with the atmosphere, it is here shown that much, maybe most, of the LOD variations are, in fact, due to the interchange of angular momentum between the “solid” Earth and the hydrosphere in a feed-back coupling system. This mechanism also operates on the decadal

  6. Reflex anuria following acute cardiac event

    OpenAIRE

    Jeevagan, Vijayabala; Navinan, Mitrakrishnan; Munasinghe, Arunie; Nazar, Abdul; Wijewardena, Anura; Constantine, Godwin

    2013-01-01

    Background Reflex anuria is an uncommon cause for acute renal failure, which occurs almost always after manipulation or irritation to kidneys, ureter, bladder or other pelvic organs. Case presentation Here we describe a case of acute renal failure due to reflex anuria following acute cardiac event. This patient had background history of urolithiasis. In the absence of other pre renal, renal or post- renal causes for acute kidney injury, we believe reflex anuria is the causative entity for acu...

  7. Frequency and distribution of winter melt events from passive microwave satellite data in the pan-Arctic, 1988-2013

    Science.gov (United States)

    Wang, Libo; Toose, Peter; Brown, Ross; Derksen, Chris

    2016-11-01

    This study presents an algorithm for detecting winter melt events in seasonal snow cover based on temporal variations in the brightness temperature difference between 19 and 37 GHz from satellite passive microwave measurements. An advantage of the passive microwave approach is that it is based on the physical presence of liquid water in the snowpack, which may not be the case with melt events inferred from surface air temperature data. The algorithm is validated using in situ observations from weather stations, snow pit measurements, and a surface-based passive microwave radiometer. The validation results indicate the algorithm has a high success rate for melt durations lasting multiple hours/days and where the melt event is preceded by warm air temperatures. The algorithm does not reliably identify short-duration events or events that occur immediately after or before periods with extremely cold air temperatures due to the thermal inertia of the snowpack and/or overpass and resolution limitations of the satellite data. The results of running the algorithm over the pan-Arctic region (north of 50° N) for the 1988-2013 period show that winter melt events are relatively rare, totaling less than 1 week per winter over most areas, with higher numbers of melt days (around two weeks per winter) occurring in more temperate regions of the Arctic (e.g., central Québec and Labrador, southern Alaska and Scandinavia). The observed spatial pattern is similar to winter melt events inferred with surface air temperatures from the ERA-Interim (ERA-I) and Modern Era-Retrospective Analysis for Research and Applications (MERRA) reanalysis datasets. There was little evidence of trends in winter melt event frequency over 1988-2013 with the exception of negative trends over northern Europe attributed to a shortening of the duration of the winter period. The frequency of winter melt events is shown to be strongly correlated to the duration of winter period. This must be taken into

  8. Ratchet due to broken friction symmetry

    DEFF Research Database (Denmark)

    Norden, Bengt; Zolotaryuk, Yaroslav; Christiansen, Peter Leth

    2002-01-01

    with it have been carried out. In this device, an asymmetry of friction dependence on an applied force appears, resulting in rectification of rotary motion, In experiments, our setup is observed to rotate only in one direction, which is in accordance with given theoretical arguments, Despite the setup being...... three dimensional, the ratchet rotary motion is proved to be described by one dynamical equation. This kind of motion is a result of the interplay of friction and inertia. We also consider a case with viscous friction, which is irrelevant to this gadget, but it can be a possible mechanism of rotary......A ratchet mechanism that occurs due to asymmetric dependence of the friction of a moving system on its velocity or a driving force is reported. For this kind of ratchet, instead of a particle moving in a periodic potential, the dynamics of which have broken space-time symmetry, the system must...

  9. Deep long-period earthquakes beneath Washington and Oregon volcanoes

    Science.gov (United States)

    Nichols, M.L.; Malone, S.D.; Moran, S.C.; Thelen, W.A.; Vidale, J.E.

    2011-01-01

    Deep long-period (DLP) earthquakes are an enigmatic type of seismicity occurring near or beneath volcanoes. They are commonly associated with the presence of magma, and found in some cases to correlate with eruptive activity. To more thoroughly understand and characterize DLP occurrence near volcanoes in Washington and Oregon, we systematically searched the Pacific Northwest Seismic Network (PNSN) triggered earthquake catalog for DLPs occurring between 1980 (when PNSN began collecting digital data) and October 2009. Through our analysis we identified 60 DLPs beneath six Cascade volcanic centers. No DLPs were associated with volcanic activity, including the 1980-1986 and 2004-2008 eruptions at Mount St. Helens. More than half of the events occurred near Mount Baker, where the background flux of magmatic gases is greatest among Washington and Oregon volcanoes. The six volcanoes with DLPs (counts in parentheses) are Mount Baker (31), Glacier Peak (9), Mount Rainier (9), Mount St. Helens (9), Three Sisters (1), and Crater Lake (1). No DLPs were identified beneath Mount Adams, Mount Hood, Mount Jefferson, or Newberry Volcano, although (except at Hood) that may be due in part to poorer network coverage. In cases where the DLPs do not occur directly beneath the volcanic edifice, the locations coincide with large structural faults that extend into the deep crust. Our observations suggest the occurrence of DLPs in these areas could represent fluid and/or magma transport along pre-existing tectonic structures in the middle crust. ?? 2010 Elsevier B.V.

  10. Long period oscillations in sunspots

    Science.gov (United States)

    Chorley, N.; Hnat, B.; Nakariakov, V. M.; Inglis, A. R.; Bakunina, I. A.

    2010-04-01

    Long period oscillations of the gyroresonant emission from sunspot atmospheres are studied. Time series data generated from the sequences of images obtained by the Nobeyama Radioheliograph operating at a frequency of 17 GHz for three sunspots have been analysed and are found to contain significant periods in the range of several tens of minutes. Wavelet analysis shows that these periods are persistent throughout the observation periods. The presence of the oscillations is confirmed by several methods (periodogram, wavelets, Fisher randomisation and empirical mode decomposition). Spatial analysis using the techniques of period, power, correlation and time lag mapping reveals regions of enhanced oscillatory power in the umbral regions. Also seen are two regions of coherent oscillation of about 25 pixels in size, that oscillate in anti-phase with each other. Possible interpretation of the observed periodicities is discussed, in terms of the shallow sunspot model and the leakage of the solar g-modes.

  11. From Periodic Properties to a Periodic Table Arrangement

    Science.gov (United States)

    Besalú, Emili

    2013-01-01

    A periodic table is constructed from the consideration of periodic properties and the application of the principal components analysis technique. This procedure is useful for objects classification and data reduction and has been used in the field of chemistry for many applications, such as lanthanides, molecules, or conformers classification.…

  12. Factors Predicting Adverse Events Associated with Pregabalin Administered for Neuropathic Pain Relief

    Directory of Open Access Journals (Sweden)

    Yuko Kanbayashi

    2014-01-01

    Full Text Available BACKGROUND:Pregabalin administration is occasionally abandoned due to adverse events such as somnolence, dizziness, unsteadiness, weight gain and edema. However, the exact causes of these differences in adverse events associated with pregabalin have not been elucidated.

  13. Protecting against natural hazards - Information seeking behaviour in anticipation of severe weather events

    NARCIS (Netherlands)

    Jeuring, Jelmer

    2011-01-01

    Protection against natural hazards - Information seeking behaviour in anticipation of severe weather events Severe weather events can have considerable impact on society, including tourism organisations and tourists. Providing accurate and timely information about possible risks due to environmental

  14. Event-Based Conceptual Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    The paper demonstrates that a wide variety of event-based modeling approaches are based on special cases of the same general event concept, and that the general event concept can be used to unify the otherwise unrelated fields of information modeling and process modeling. A set of event......-based modeling approaches are analyzed and the results are used to formulate a general event concept that can be used for unifying the seemingly unrelated event concepts. Events are characterized as short-duration processes that have participants, consequences, and properties, and that may be modeled in terms...... of information structures. The general event concept can be used to guide systems analysis and design and to improve modeling approaches....

  15. Extinction Events Can Accelerate Evolution

    DEFF Research Database (Denmark)

    Lehman, Joel; Miikkulainen, Risto

    2015-01-01

    Extinction events impact the trajectory of biological evolution significantly. They are often viewed as upheavals to the evolutionary process. In contrast, this paper supports the hypothesis that although they are unpredictably destructive, extinction events may in the long term accelerate...

  16. Does a cardiovascular event change adherence to statin treatment in patients with type 2 diabetes? A matched cohort design.

    Science.gov (United States)

    de Vries, F M; Denig, P; Vegter, S; Bos, H J; Postma, M J; Hak, E

    2015-04-01

    To be effective, adherence to statin treatment is essential. We assessed the effect of an apparent first cardiovascular event on statin adherence rates in type 2 diabetes patients. A matched cohort study was conducted among type 2 diabetes patients initiating statin treatment for primary prevention in the Groningen University IADB.nl pharmacy database. Patients who had a drug-treated cardiovascular event (index date) after statin initiation were matched to a reference patient without such an event with similar gender, age at statin initiation, initiation date, follow-up period and adherence level before the event. Adherence rates were measured as percentages of days covered (PDC), and shifts in adherence levels (non-adherent/partially adherent/fully adherent) and rates around the event were evaluated. We could match 375 of the 855 eligible index patients to a reference patient. Index patients had on average a PDC of 81% after the index date; reference patients had a PDC of 71% (p < 0.001) while both had a PDC of 79% before the index date. Index patients were 4.5 times more likely than reference patients to shift from non-adherent to fully adherent (95% CI 1.1-18.8) and 1.8 times more likely to shift from partially adherent to fully adherent (95% CI 1.2-2.6). In the index group, 26% of patients became more adherent after the first cardiovascular event. In contrast, 20% of patients became less adherent. Medication proxies were used, which could have caused misclassification. Furthermore, a substantial group of index patients could not be matched to a reference patient due to small ranges in matching criteria. The occurrence of a drug-treated cardiovascular event appeared to avert the declining statin adherence rate observed in diabetes patients without such an event. On the other hand, one in five patients became less adherent after the event, indicating that there are still important benefits to achieve.

  17. The 2014 coral bleaching and freshwater flood events in Kāne'ohe Bay, Hawai'i.

    Science.gov (United States)

    Bahr, Keisha D; Jokiel, Paul L; Rodgers, Kuʻulei S

    2015-01-01

    Until recently, subtropical Hawai'i escaped the major bleaching events that have devastated many tropical regions, but the continued increases in global long-term mean temperatures and the apparent ending of the Pacific Decadal Oscillation (PDO) cool phase have increased the risk of bleaching events. Climate models and observations predict that bleaching in Hawai'i will occur with increasing frequency and increasing severity over future decades. A freshwater "kill" event occurred during July 2014 in the northern part of Kāne'ohe Bay that reduced coral cover by 22.5% in the area directly impacted by flooding. A subsequent major bleaching event during September 2014 caused extensive coral bleaching and mortality throughout the bay and further reduced coral cover in the freshwater kill area by 60.0%. The high temperature bleaching event only caused a 1.0% reduction in live coral throughout the portion of the bay not directly impacted by the freshwater event. Thus, the combined impact of the low salinity event and the thermal bleaching event appears to be more than simply additive. The temperature regime during the September 2014 bleaching event was analogous in duration and intensity to that of the large bleaching event that occurred previously during August 1996, but resulted in a much larger area of bleaching and coral mortality. Apparently seasonal timing as well as duration and magnitude of heating is important. Coral spawning in the dominant coral species occurs early in the summer, so reservoirs of stored lipid in the corals had been depleted by spawning prior to the September 2014 event. Warm months above 27 °C result in lower coral growth and presumably could further decrease lipid reserves, leading to a bleaching event that was more severe than would have happened if the high temperatures occurred earlier in the summer. Hawaiian reef corals decrease skeletal growth at temperatures above 27 °C, so perhaps the "stress period" actually started long before the

  18. Projections of hepatitis A virus infection associated with flood events by 2020 and 2030 in Anhui Province, China.

    Science.gov (United States)

    Gao, Lu; Zhang, Ying; Ding, Guoyong; Liu, Qiyong; Wang, Changke; Jiang, Baofa

    2016-12-01

    Assessing and responding to health risk of climate change is important because of its impact on the natural and societal ecosystems. More frequent and severe flood events will occur in China due to climate change. Given that population is projected to increase, more people will be vulnerable to flood events, which may lead to an increased incidence of HAV infection in the future. This population-based study is going to project the future health burden of HAV infection associated with flood events in Huai River Basin of China. The study area covered four cities of Anhui province in China, where flood events were frequent. Time-series adjusted Poisson regression model was developed to quantify the risks of flood events on HAV infection based on the number of daily cases during summer seasons from 2005 to 2010, controlling for other meteorological variables. Projections of HAV infection in 2020 and 2030 were estimated based on the scenarios of flood events and demographic data. Poisson regression model suggested that compared with the periods without flood events, the risks of severe flood events for HAV infection were significant (OR = 1.28, 95 % CI 1.05-1.55), while risks were not significant from moderate flood events (OR = 1.16, 95 % CI 0.72-1.87) and mild flood events (OR = 1.14, 95 % CI 0.87-1.48). Using the 2010 baseline data and the flood event scenarios (one severe flood event), increased incidence of HAV infection were estimated to be between 0.126/10(5) and 0.127/10(5) for 2020. Similarly, the increased HAV infection incidence for 2030 was projected to be between 0.382/10(5) and 0.399/10(5). Our study has, for the first time, quantified the increased incidence of HAV infection that will result from flood events in Anhui, China, in 2020 and 2030. The results have implications for public health preparation for developing public health responses to reduce HAV infection during future flood events.

  19. Projections of hepatitis A virus infection associated with flood events by 2020 and 2030 in Anhui Province, China

    Science.gov (United States)

    Gao, Lu; Zhang, Ying; Ding, Guoyong; Liu, Qiyong; Wang, Changke; Jiang, Baofa

    2016-12-01

    Assessing and responding to health risk of climate change is important because of its impact on the natural and societal ecosystems. More frequent and severe flood events will occur in China due to climate change. Given that population is projected to increase, more people will be vulnerable to flood events, which may lead to an increased incidence of HAV infection in the future. This population-based study is going to project the future health burden of HAV infection associated with flood events in Huai River Basin of China. The study area covered four cities of Anhui province in China, where flood events were frequent. Time-series adjusted Poisson regression model was developed to quantify the risks of flood events on HAV infection based on the number of daily cases during summer seasons from 2005 to 2010, controlling for other meteorological variables. Projections of HAV infection in 2020 and 2030 were estimated based on the scenarios of flood events and demographic data. Poisson regression model suggested that compared with the periods without flood events, the risks of severe flood events for HAV infection were significant (OR = 1.28, 95 % CI 1.05-1.55), while risks were not significant from moderate flood events (OR = 1.16, 95 % CI 0.72-1.87) and mild flood events (OR = 1.14, 95 % CI 0.87-1.48). Using the 2010 baseline data and the flood event scenarios (one severe flood event), increased incidence of HAV infection were estimated to be between 0.126/105 and 0.127/105 for 2020. Similarly, the increased HAV infection incidence for 2030 was projected to be between 0.382/105 and 0.399/105. Our study has, for the first time, quantified the increased incidence of HAV infection that will result from flood events in Anhui, China, in 2020 and 2030. The results have implications for public health preparation for developing public health responses to reduce HAV infection during future flood events.

  20. Applied periodization: a methodological approach

    OpenAIRE

    Naclerio, Fernando; Moody, Jeremy; Chapman, Mark

    2013-01-01

    Periodization represents an optimal modality for organizing training programs in athletes, recreational and rehabilitative practitioners. The selected procedure, however, should be based on the athlete’s age, level of performance, specific goals or competition characteristics. A common theme throughout all periodization paradigms is the requirement to manipulate the entire program variables (intensity, volume, frequency, recovery periods and exercise selection) in order to progress from gener...

  1. Sensitivity analysis of potential events affecting the double-shell tank system and fallback actions

    Energy Technology Data Exchange (ETDEWEB)

    Knutson, B.J.

    1996-09-27

    Sensitivity analyses were performed for fall-back positions (i.e., management actions) to accommodate potential off-normal and programmatic change events overlaid on the waste volume projections and their uncertainties. These sensitivity analyses allowed determining and ranking tank system high-risk parameters and fall- back positions that will accommodate the respective impacts. This quantification of tank system impacts shows periods where tank capacity is sensitive to certain variables that must be carefully managed and/or evaluated. Identifying these sensitive variables and quantifying their impact will allow decision makers to prepare fall-back positions and focus available resources on the highest impact parameters where technical data are needed to reduce waste projection uncertainties. For noncomplexed waste, the period of capacity vulnerability occurs during the years of single-shell tank (SST) retrieval (after approximately 2009) due to the sensitivity to several variables. Ranked by importance these variables include the pretreatment rate and 200-East SST solids transfer volume. For complexed waste, the period of capacity vulnerability occurs during the period after approximately 2005 due to the sensitivity to several variables. Ranked by importance these variables include the pretreatment rate. 200-East SST solids transfer volume. complexed waste reduction factor using evaporation, and 200-west saltwell liquid porosity.

  2. [Infections due to Mycobacterium simiae].

    Science.gov (United States)

    García-Martos, Pedro; García-Agudo, Lidia; González-Moya, Enrique; Galán, Fátima; Rodríguez-Iglesias, Manuel

    2015-10-01

    Mycobacterium simiae is a slow-growing photochromogenic environmental mycobacterium, first described in 1965. Rarely associated with human infections, possibly due to its limited pathogenicity, it mainly produces lung infection in immunocompetent elderly patients with underlying lung disease, and in disseminated infections in immunosuppressed young patients with AIDS. A microbiological culture is needed to confirm the clinical suspicion, and genetic sequencing techniques are essential to correctly identify the species. Treating M. simiae infections is complicated, owing to the multiple resistance to tuberculous drugs and the lack of correlation between in vitro susceptibility data and in vivo response. Proper treatment is yet to be defined, but must include clarithromycin combined with other antimicrobials such as moxifloxacin and cotrimoxazole. It is possible that M. simiae infections are undiagnosed. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  3. APPENDICULAR INVAGINATION DUE TO ENDOMETRIOSIS

    Directory of Open Access Journals (Sweden)

    Vasja Kruh

    2003-12-01

    Full Text Available Background. Invagination of the vermiform appendix is a very rare occurrence. We summarize epidemiologic and etiologic factors, types of classification, symtomatology, diagnostic features and treatment.Patients and treatment. The authors present 49-years old female with long-standing abdominal pains, who came in our hospital due to acute exacerbation with sever abdominal pain. Because of progressive symptoms and sensitivity in the right-lower abdominal quadrant a diagnostic laparoscopy was performed. An anomaly of cecum and the absence of appendix vermiformis have forced us to proceed with laparotomy in McBurnay point. After cecotomy an invaginated gangrenous appendix was found. The histological examination revealed endometriosis.Conclusions. By presenting this extremely rare pathology we also want to emphasize the important role of diagnostic laparoscopy in front of acute abdomen.

  4. Medicine in Balkans during the Roman Period.

    Science.gov (United States)

    Baykan, Daniş

    2017-08-04

    The aim of this study is to investigate the archaeological finds to enlighten the medical methods of treatments and operations applied in Balkans during Roman Period. Some independent local and regional find groups, taken from existing publications will be grouped together and a holistic point-of-view will be taken against medicine in Balkan Geography during Roman Period. Due to basic differences it contained, the data before Roman Period are excluded. Most of Greece and Aegean Islands are also excluded since the topic selected is "Medicine of Roman Period." Greece and Aegean Islands should be evaluated in another study in connection with West Anatolia which is closer than the Balkan Geography in terms of social relations. The spread of medical tools in Balkans during Roman Period is concentrated around military garrisons, and in settlements built around military pathways, and in settlements containing an amphitheater associated with gladiators. This spread is verified by the studies on Bulgaria in general. The data is also compatible with the assertion suggesting that the amount of application of pharmaceutical treatment increases when one moves away from the military centres.

  5. Assessing periodicity of periodic leg movements during sleep.

    Science.gov (United States)

    Rummel, Christian; Gast, Heidemarie; Schindler, Kaspar; Müller, Markus; Amor, Frédérique; Hess, Christian W; Mathis, Johannes

    2010-01-01

    Periodic leg movements (PLM) during sleep consist of involuntary periodic movements of the lower extremities. The debated functional relevance of PLM during sleep is based on correlation of clinical parameters with the PLM index (PLMI). However, periodicity in movements may not be reflected best by the PLMI. Here, an approach novel to the field of sleep research is used to reveal intrinsic periodicity in inter movement intervals (IMI) in patients with PLM. Three patient groups of 10 patients showing PLM with OSA (group 1), PLM without OSA or RLS (group 2) and PLM with RLS (group 3) are considered. Applying the "unfolding" procedure, a method developed in statistical physics, enhances or even reveals intrinsic periodicity of PLM. The degree of periodicity of PLM is assessed by fitting one-parameter distributions to the unfolded IMI distributions. Finally, it is investigated whether the shape of the IMI distributions allows to separate patients into different groups. Despite applying the unfolding procedure, periodicity is neither homogeneous within nor considerably different between the three clinically defined groups. Data-driven clustering reveals more homogeneous and better separated clusters. However, they consist of patients with heterogeneous demographic data and comorbidities, including RLS and OSA. The unfolding procedure may be necessary to enhance or reveal periodicity. Thus this method is proposed as a pre-processing step before analyzing PLM statistically. Data-driven clustering yields much more reasonable results when applied to the unfolded IMI distributions than to the original data. Despite this effort no correlation between the degree of periodicity and demographic data or comorbidities is found. However, there are indications that the nature of the periodicity might be determined by long-range interactions between LM of patients with PLM and OSA.

  6. Assessing periodicity of periodic leg movements during sleep

    Directory of Open Access Journals (Sweden)

    Christian eRummel

    2010-09-01

    Full Text Available Background: Periodic leg movements during sleep (PLMS consist of involuntary periodic movements of the lower extremities. The debated functional relevance of PLMS is based on correlation of clinical parameters with the PLMS index (PLMI. However, periodicity in movements may not be reflected best by the PLMI. Here, an approach novel to the field of sleep research is used to reveal intrinsic periodicity in inter movement intervals (IMI in patients with PLMS. Methods: Three patient groups of 10 patients showing PLMS with OSA (group 1, PLMS without OSA or RLS (group 2 and PLMS with RLS (group 3 were considered. Applying the ``unfolding'' procedure, a method developed in statistical physics, enhanced or even revealed intrinsic periodicity of PLMS. The degree of periodicity of PLMS was assessed by fitting one-parameter distributions to the unfolded IMI distributions. Finally, it was investigated whether the shape of the IMI distributions allows to separate patients into different groups. Results: Despite applying the unfolding procedure, periodicity was neither homogeneous within nor considerably different between the three clinically defined groups. Data-driven clustering revealed more homogeneous and better separated clusters. However, they consisted of patients with heterogeneous demographic data and comorbidities, including RLS {em and} OSA. Conclusions: The unfolding procedure may be necessary to enhance or reveal periodicity. Thus this method is proposed as a pre-processing step before analyzing PLMS statistically. Data-driven clustering yields much more reasonable results when applied to the unfolded IMI distributions than to the original data. Despite this effort no correlation between the {em degree} of periodicity and demographic data or comorbidities was found. However, there were indications that the {em nature} of the periodicity might be determined by long-range interactions between LM of patients with PLMS and OSA.

  7. The Infinite Latent Events Model

    CERN Document Server

    Wingate, David; Roy, Daniel; Tenenbaum, Joshua

    2012-01-01

    We present the Infinite Latent Events Model, a nonparametric hierarchical Bayesian distribution over infinite dimensional Dynamic Bayesian Networks with binary state representations and noisy-OR-like transitions. The distribution can be used to learn structure in discrete timeseries data by simultaneously inferring a set of latent events, which events fired at each timestep, and how those events are causally linked. We illustrate the model on a sound factorization task, a network topology identification task, and a video game task.

  8. The ATLAS Student Event Challenge

    CERN Document Server

    Fassouliotis, D; Roupas, Z; Vudragovic, D

    2007-01-01

    The ASEC (ATLAS Student Event Challenge) is an educational project which allows the students to learn about the elementary particles by studying "events", the products of beam collisions at the LHC. The events are collected by the ATLAS detector and displayed graphically using the ATLANTIS package. The students are given the means to select and analyse the events on-line, and subsequently present the results and draw conclusions.

  9. Changes in "hotter and wetter" events across China

    Science.gov (United States)

    Liu, C.; Deng, H.; Lu, Y.; Qiu, X.; Wang, D.

    2017-12-01

    As global warming intensifies, efforts to understand the changes in extreme climate events have increased in recent years. A combined analysis of the changes in extreme temperature and precipitation events is presented in this paper. Using observational data from 1961 to 2015, a set of hotter and wetter (HW) events is defined, and we examine the changes in these events across China. The results show that more HW events occur in Central and Eastern China than in other subregions, especially in South China (SC). The rate of increase in HW events is 2.7 and 1.9 per decade in SC and East China (EC), respectively. In China, most HW events occurred in the last 20 years of the study period, indicating that China entered a period of high-frequency HW events. Indeed, the range in anomalies in the torrential rain days is greater than that of the high-temperature days in Northwest China (NWC), Central China (CC), and EC after the mid- to late 1990s. The opposite pattern is found in Northeast China (NEC), Southwest China-region 1 (SWC1), Southwest China-region 2 (SWC2), and SC. Finally, the increase in HW events in most regions of China is closely associated with warming.

  10. Measuring the effects of extreme weather events on yields

    Directory of Open Access Journals (Sweden)

    J.P. Powell

    2016-06-01

    Full Text Available Extreme weather events are expected to increase worldwide, therefore, anticipating and calculating their effects on crop yields is important for topics ranging from food security to the economic viability of biomass products. Given the local nature of weather, particularly precipitation, effects are best measured at a local level. This paper analyzes weather events at the level of the farm for a specific crop, winter wheat. Once it has been established that extreme events are expected to continue occurring at historically high levels for farming locations throughout the Netherlands, the effects of those events on wheat yields are estimated while controlling for the other major input factors affecting yields. Econometric techniques are applied to an unbalanced panel data set of 334 farms for a period of up to 12 years. Analyzes show that the number of days with extreme high temperatures in Dutch wheat growing regions has significantly increased since the early 1900s, while the number of extreme low temperature events has fallen over that same period. The effects of weather events on wheat yields were found to be time specific in that the week in which an event occurred determined its effect on yields. High temperature events and precipitation events were found to significantly decrease yields.

  11. PATHOGENESIS OF HEMORRHAGIC DUE TO DENGUE VIRUS

    Directory of Open Access Journals (Sweden)

    Arief Suseno

    2015-01-01

    Full Text Available Dengue is a viral disease that is mediated by a mosquito, which causes morbidity and mortality. Viruses can increase vascular permeability which can lead to hemorrhagic diathesis or disseminated intravascular coagulation (DIC known as dengue hemorrhagic fever (DHF. In Indonesia, dengue hemorrhagic fever (DHF are caused by dengue virus infection which was found to be endemic accompanied by an explosion of extraordinary events that appear at various specified period. The diagnosis of dengue is determined based on the criteria of the World Health Organization (WHO, 1999, which are sudden high fever accompanied by a marked tendency to hemorrhage positive tourniquet test, petechiae, ecchymosis, purpura, mucosal hemorrhagic, hematemesis or melena and thrombocytopenia. The problem that still exists today is the mechanism of thrombocytopenia in patients with varying degrees of dengue involving levels of vWF (von Willebrand factor and prostaglandin I2 (PGI2 can not be explained. The mechanism of hemorrhagic in dengue virus infections acquired as a result of thrombocytopenia, platelet disfunction decreased coagulation factors, vasculopathy with endothelial injury and disseminated intravascular coagulation (DIC.

  12. Integrity & sport events: Position paper

    NARCIS (Netherlands)

    Hover, P.; Dijk, B.; Breedveld, K.; Eekeren, F.J.A. van

    2016-01-01

    Sport events are appreciated as important sources of inspiration and positive energy. Yet, for a growing number of people, the negative aspects of sport events have come to cast a shadow over sport events as a positive experience. Questions and doubts have been raised about the transparency and good

  13. Stimuli, Reinforcers, and Private Events

    Science.gov (United States)

    Nevin, John A.

    2008-01-01

    Radical behaviorism considers private events to be a part of ongoing observable behavior and to share the properties of public events. Although private events cannot be measured directly, their roles in overt action can be inferred from mathematical models that relate private responses to external stimuli and reinforcers according to the same…

  14. [Deaths due to non-AIDS diseases among HIV infected patients: A 14-year study (1998-2011)].

    Science.gov (United States)

    López, Cristina; Masiá, Mar; Padilla, Sergio; Aquilino, Ana; Bas, Cristina; Gutiérrez, Félix

    2016-04-01

    The objective of this study was to analyze the deaths caused by non-AIDS diseases in a cohort of HIV-infected patients treated between 1998 and 2011. Information on the causes of death was collected retrospectively, and then classified according to the deaths code (CoDe) algorithm. Patient characteristics and causes of death were compared for two periods: 1998-2004 and 2005-2011. A total of 159 out of the 1070 patients cared for in study period died, 56 (35%) due to AIDS events and 86 (54%) due to non-AIDS events (NAEs); in 17 (11%) the cause of death could not be determined. Overall, the main causes of death were infections (32%), cancer (17%), and unnatural deaths (17%). There was lower mortality from AIDS-related conditions during the second period (18.5% vs 47%; Pdeaths from cardiovascular disease (9.2% vs 2.1%, P=.06). Patients who died in the second period were older, and had a better immunological and virological status at cohort entry and before death. They received antiretroviral therapy (ART) more often and were more often virologically suppressed before death (61.5% vs 24%; P=.001). Non-AIDS-defining cancers, unnatural deaths, and cardiovascular diseases are now major causes of death in patients with HIV. In recent years the majority of deceased patients are on ART and with virological suppression. Copyright © 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  15. Adaptation to flood risk: Results of international paired flood event studies

    Science.gov (United States)

    Kreibich, Heidi; Di Baldassarre, Giuliano; Vorogushyn, Sergiy; Aerts, Jeroen C. J. H.; Apel, Heiko; Aronica, Giuseppe T.; Arnbjerg-Nielsen, Karsten; Bouwer, Laurens M.; Bubeck, Philip; Caloiero, Tommaso; Chinh, Do T.; Cortès, Maria; Gain, Animesh K.; Giampá, Vincenzo; Kuhlicke, Christian; Kundzewicz, Zbigniew W.; Llasat, Maria Carmen; Mârd, Johanna; Matczak, Piotr; Mazzoleni, Maurizio; Molinari, Daniela; Dung, Nguyen V.; Petrucci, Olga; Schröter, Kai; Slager, Kymo; Thieken, Annegret H.; Ward, Philip J.; Merz, Bruno

    2017-10-01

    As flood impacts are increasing in large parts of the world, understanding the primary drivers of changes in risk is essential for effective adaptation. To gain more knowledge on the basis of empirical case studies, we analyze eight paired floods, that is, consecutive flood events that occurred in the same region, with the second flood causing significantly lower damage. These success stories of risk reduction were selected across different socioeconomic and hydro-climatic contexts. The potential of societies to adapt is uncovered by describing triggered societal changes, as well as formal measures and spontaneous processes that reduced flood risk. This novel approach has the potential to build the basis for an international data collection and analysis effort to better understand and attribute changes in risk due to hydrological extremes in the framework of the IAHSs Panta Rhei initiative. Across all case studies, we find that lower damage caused by the second event was mainly due to significant reductions in vulnerability, for example, via raised risk awareness, preparedness, and improvements of organizational emergency management. Thus, vulnerability reduction plays an essential role for successful adaptation. Our work shows that there is a high potential to adapt, but there remains the challenge to stimulate measures that reduce vulnerability and risk in periods in which extreme events do not occur.

  16. Allergic contact cheilitis due to lipstick

    Directory of Open Access Journals (Sweden)

    Yatty Ravitasari

    2015-12-01

    Full Text Available Background: Cheilitis is a common problem of unknown etiology. A possible cause of cheilitis is contact allergy. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. Allergic contact cheilitis is a chronic superficial inflammatory disorder of the vermilion borders characterized by desquamation due to delayed-type hypersensitivity reaction. Purpose: We report a management of Allergic contact cheilitis due to lipsticks. Case: A 21-year-old woman had a history of atopic allergy to eggs, milk, and chicken presented with sore, dry, fissured, scaled and sometimes bleeding lip, over a 3-month period after application of a lipstick. Her symptoms persisted despite treatments with hydrocortisone cream. The patient provided a detailed history and underwent physical examination and patch tests to cosmetic components and patch test to her own lipstick. The patient had strongly-positive result to the tested lipstick. A diagnosis of allergic contact cheilitis was made based on the history and clinical findings. Case management: Patient was advised to avoid wearing lipstick. To relieve symptoms, treatment was initiated with combined topical corticosteroid, antibiotic, and moisturizer. Conclusion: Contact allergy patients should be tested for both cosmetic component series and their own lipsticks to exclude exfolliative cheilitis, infection, or light actinic cheilitis as causal agents.

  17. Quasi-periodicity in relative quasi-periodic tori

    Science.gov (United States)

    Fassò, Francesco; García-Naranjo, Luis C.; Giacobbe, Andrea

    2015-10-01

    At variance from the cases of relative equilibria and relative periodic orbits of dynamical systems with symmetry, the dynamics in relative quasi-periodic tori (namely, subsets of the phase space that project to an invariant torus of the reduced system on which the flow is quasi-periodic) is not yet completely understood. Even in the simplest situation of a free action of a compact and abelian connected group, the dynamics in a relative quasi-periodic torus is not necessarily quasi-periodic. It is known that quasi-periodicity of the unreduced dynamics is related to the reducibility of the reconstruction equation, and sufficient conditions for it are virtually known only in a perturbation context. We provide a different, though equivalent, approach to this subject, based on the hypothesis of the existence of commuting, group-invariant lifts of a set of generators of the reduced torus. Under this hypothesis, which is shown to be equivalent to the reducibility of the reconstruction equation, we give a complete description of the structure of the relative quasi-periodic torus, which is a principal torus bundle whose fibers are tori of a dimension which exceeds that of the reduced torus by at most the rank of the group. The construction can always be done in such a way that these tori have minimal dimension and carry ergodic flow.

  18. The Chelyabinsk event

    Science.gov (United States)

    Borovička, Jiří

    2016-10-01

    On February 15, 2013, 3:20 UT, an asteroid of the size of about 19 meters and mass of 12,000 metric tons entered the Earth's atmosphere unexpectedly near the border of Kazakhstan and Russia. It was the largest confirmed Earth impactor since the Tunguska event in 1908. The body moved approximately westwards with a speed of 19 km s-1, on a trajectory inclined 18 degrees to the surface, creating a fireball of steadily increasing brightness. Eleven seconds after the first sightings, the fireball reached its maximum brightness. At that point, it was located less than 40 km south from Chelyabinsk, a Russian city of population more than one million, at an altitude of 30 km. For people directly underneath, the fireball was 30 times brighter than the Sun. The cosmic body disrupted into fragments; the largest of them was visible for another five seconds before it disappeared at an altitude of 12.5 km, when it was decelerated to 3 km s-1. Fifty six second later, that ~600 kg fragment landed in Lake Chebarkul and created a 8 m wide hole in the ice. Small meteorites landed in an area 80 km long and several km wide and caused no damage. The meteorites were classified as LL ordinary chondrites and were interesting by the presence of two phases, light and dark. More material remained, however, in the atmosphere forming a dust trail up to 2 km wide and extending along the fireball trajectory from altitude 18 to 70 km. The dust then circled the Earth within few days and formed a ring around the northern hemisphere. In Chelyabinsk and its surroundings a very strong blast wave arrived 90 - 150 s after the fireball passage (depending on location). The wave was produced by the supersonic flight of the body and broke ~10% of windows in Chelyabinsk (~40% of buildings were affected). More than 1600 people were injured, mostly from broken glass. The whole event was well documented by video cameras, seismic and infrasonic records, and satellite observations. The total energy was 500 kT TNT

  19. Elegent -- an elastic event generator

    CERN Document Server

    Kašpar, Jan

    2014-01-01

    Although elastic scattering of nucleons may look like a simple process, it presents a long-lasting challenge for theory. Due to missing hard energy scale, the perturbative QCD can not be applied. Instead, many phenomenological/theoretical models have emerged. In this paper we present a unified implementation of some of the most prominent models in a C++ library, moreover extended to account for effects of the electromagnetic interaction. The library is complemented with a number of utilities. For instance, programs to sample many distributions of interest in four-momentum transfer squared, t, impact parameter, b, and collision energy sqrt(s). These distributions at ISR, SppS, RHIC, Tevatron and LHC energies are available for download from the project web site. Both in the form of ROOT files and PDF figures providing comparisons among the models. The package includes also a tool for Monte-Carlo generation of elastic scattering events, which can easily be embedded in any other program framework.

  20. Detecting periodicities with Gaussian processes

    Directory of Open Access Journals (Sweden)

    Nicolas Durrande

    2016-04-01

    Full Text Available We consider the problem of detecting and quantifying the periodic component of a function given noise-corrupted observations of a limited number of input/output tuples. Our approach is based on Gaussian process regression, which provides a flexible non-parametric framework for modelling periodic data. We introduce a novel decomposition of the covariance function as the sum of periodic and aperiodic kernels. This decomposition allows for the creation of sub-models which capture the periodic nature of the signal and its complement. To quantify the periodicity of the signal, we derive a periodicity ratio which reflects the uncertainty in the fitted sub-models. Although the method can be applied to many kernels, we give a special emphasis to the Matérn family, from the expression of the reproducing kernel Hilbert space inner product to the implementation of the associated periodic kernels in a Gaussian process toolkit. The proposed method is illustrated by considering the detection of periodically expressed genes in the arabidopsis genome.

  1. Quasi Periodic Oscillations in Blazars

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Home; Journals; Journal of Astrophysics and Astronomy; Volume 35; Issue 3. Quasi Periodic Oscillations in Blazars ... Here we report our recent discoveries of Quasi-Periodic Oscillations (QPOs) in blazars time series data in X-ray and optical electromagnetic bands. Any such detection can give important ...

  2. Demand response pilot event conducted August 2,2011 : summary report.

    Energy Technology Data Exchange (ETDEWEB)

    Lincoln, Donald; Evans, Christoper

    2012-01-01

    Energy management in a commercial facility can be segregated into two areas: energy efficiency and demand response (DR). Energy efficiency focuses on steady-state load minimization. Demand response reduces load for event driven periods during the peak load. Demand-response-driven changes in electricity use are designed to be short-term in nature, centered on critical hours during the day when demand is high or when the electricity supplier's reserve margins are low. Due to the recent Federal Energy Regulatory Commission (FERC) Order 745, Demand Response Compensation in Organized Wholesale Energy Markets the potential annual compensation to Sandia National Laboratories (SNL) from performing DR ranges from $300K to $2,400K. While the current energy supply contract does not offer any compensation for participating in DR, there is benefit in understanding the issues and potential value in performing a DR event. This Report will be helpful in upcoming energy supply contract negotiations to quantify the energy savings and power reduction potential from DR at SNL. On August 25, 2011 the Facilities Management and Operations Center (FMOC) performed the first DR pilot event at SNL/NM. This report describes the details and results of this DR event.

  3. Assessment for the impact of dust events on measles incidence in western China

    Science.gov (United States)

    Ma, Yuxia; Zhou, Jianding; Yang, Sixu; Zhao, Yuxin; Zheng, Xiaodong

    2017-05-01

    Dust events affect human health in both drylands and downwind environments. In this study, we used county-level data during the period of 1965-2005 to assess the impact of dust events on measles incidence in Gansu province in Western China. We used Fast Fourier Transform (FFT) to set up the cyclical regression model; in particular, we set the model to downwind direction for the typical cities in the Hexi Corridor as well as the capital city Lanzhou. The results showed that Spring measles incidence was the highest in the Hexi Corridor, where dust events occur the most frequently over Gansu province. Measles incidence declined on the pathway of dust storms from west to east due to the weakening of both intensity and duration in dust storms. Measles incidence was positively correlated with monthly wind speed and negatively correlated with rainfall amount, relative humidity, and air pressure. Measles incidence was significantly (p ≤ 0.01) positively correlated with daily coarse particles, e.g., TSP and PM10. According to the cyclical regression model, average monthly excess measles that is related to dust events was 39.1 (ranging from 17.3 to 87.6), 149.9 (ranging from 7.1 to 413.4), and 31.3 (ranging from 20.6 to 63.5) in Zhangye, Lanzhou, and Jiuquan, respectively.

  4. Recent drainage events of glacial Lake Cachet 2, Patagonia

    Science.gov (United States)

    Casassa, G.; Wendt, J.; Wendt, A.; Escobar, F.; Lopez, P.; Carrasco, J.; Rivera, A.; Leidich, J.

    2009-04-01

    Lake Cachet 2 (47°12' S, 73°15' W, 422 m a.s.l.) is a proglacial lake of 4 km2 located on the eastern margin of the Northern Patagonia Icefield (3,953 km2, Rivera et al., 2007), which is dammed on its southern margin by Colonia Glacier. Until April 2008 there was no historical evidence of catastrophic flooding of this lake. In 2008 three sudden drainage events occurred at Lake Cachet 2 (April 6-7; October 7-8 and 21-22 December). During each event the flood wave traveled down Colonia River to the confluence with Baker River, then affected Baker River to a distance of up to 25 km upstream from the confluence and downstream all the way to its mouth on the Pacific Ocean fjords at Caleta Tortel (100 km to the southwest), transporting abundant sediments. In April the runoff of Baker River close to the confluence with Colonia River increased from a base level of 1,200 m3/s on April 7 to a peak runoff of 3,570 m3/s within a period of less than 48 hours, resulting in a river level increase of 4.5 m and an associated water temperature drop from 8°C to 4°C. In October the base level was 573 m3/s, with a peak runoff of 3,007 m3/s, a river level increase of 4.7 m and a water temperature drop from 7.3°C to 4.8°C, while in December the corresponding values were 1,145 m3/s, 3,052 m3/s, 11°C and 8°C. The flood affected roads, bridges, farms and cattle, fortunately not resulting in any human damage. Similar floods had been reported on Colonia River several decades ago, the last having occurred in the 1970s, all of which originated at that time at glacial Lake Arco, located south of Colonia Glacier. Airborne and ground explorations carried out after each event in 2008 confirmed that the floods originated at Lake Cachet 2, draining under Colonia Glacier for a distance of 8 km and emerging at the front of the glacier. As a result parts of the glacier front collapsed after each event, where large ice fractures could be observed. During the October event a complete drainage of

  5. Wrong tooth extraction: an examination of 'Never Event' data.

    Science.gov (United States)

    Pemberton, M N; Ashley, M P; Saksena, A; Dickson, S

    2017-02-01

    The NHS in England has identified several adverse incidents that involve patients, including operations done at the wrong site, as "never" events. We examined published data from the period April 2012 to October 2015 and found that "wrong tooth/teeth removed" is the most common "wrong site" event, and accounted for between 20% and 25% of wrong site surgery never events, and 6% - 9% of all "never" events. All "wrong tooth/teeth removed" events seem to have been reported only by hospitals or Community Trusts. It is important to find out how these events are recorded and to find ways to prevent them. Crown Copyright © 2016. Published by Elsevier Ltd. All rights reserved.

  6. EVENT PLANNING USING FUNCTION ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    Lori Braase; Jodi Grgich

    2011-06-01

    Event planning is expensive and resource intensive. Function analysis provides a solid foundation for comprehensive event planning (e.g., workshops, conferences, symposiums, or meetings). It has been used at Idaho National Laboratory (INL) to successfully plan events and capture lessons learned, and played a significant role in the development and implementation of the “INL Guide for Hosting an Event.” Using a guide and a functional approach to planning utilizes resources more efficiently and reduces errors that could be distracting or detrimental to an event. This integrated approach to logistics and program planning – with the primary focus on the participant – gives us the edge.

  7. Transient hypofibrinogenemia due to allopurinol

    Directory of Open Access Journals (Sweden)

    Yin ZQ

    2014-09-01

    Full Text Available ZhiQiang Yin,1,* JiaLi Xu,2,* YongQiang Li,3,* JiPing Xia,1 Dan Luo1 1Department of Dermatology, 2Department of Oncology, 3Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China *These authors contributed equally to this work Abstract: This study reports a case of an 80-year-old male who suffered from drug eruption due to oral allopurinol for the treatment of gout. This patient complained of widespread erythema and maculopapule with itch, and small quantities of purplish-red rash with diffused distribution on four limbs were noted. After he was hospitalized, the area with purpuric rash increased in size, and hypofibrinogenemia was found. After treatment with intravenous infusion of fibrinogen and cryoprecipitate, and continued treatment with high-dose methylprednisolone, the skin rash gradually went away. This is the first report of purpura and hypofibrinogenemia induced by allopurinol and the pathophysiology underlying this reaction remained unknown. Keywords: purpura, fibrinogen, drug eruption, gout

  8. [Organ alterations due to aging].

    Science.gov (United States)

    Wieczorowska-Tobis, Katarzyna

    2008-01-01

    Aging defined as progressive organ dysfunction which makes keeping homeostasis more difficult starts at the age of 30-40. However, due to difficulties with the distinction between aging and disease processes, changes previously believed to be caused by aging are often recognized as the effect of pathologies when new data is presented. According to current knowledge, cardio-vascular aging includes decreased elasticity of main arteries, decreased ability of left ventricule to relaxate, diminished function of sino-atrial node and decreased effect of beta-adrenergic stimulation. Aging in the respiratory system is attributed to increased size of alveoli and alveolar ducts (which easier collapse), a decrease in the gase exchange area, a decrease in respiratory volumes (both static and dynamic) and a severe decrease in maximal oxygen consumption. In aging kidneys both renal blood flow and glomerular filtration are decreased. As the result of tubular alterations the kidney ability to conserve and dilute urine, and its capability to regulate the pH and serum sodium level diminish. Less dramatic changes are seen in the gastrointestinal tract. According to available data, high prevalence of gastric atrophy and hypochlorhydria are a consequence of Helicobacter pylori infection. Also, constipation is attributed much more to sedative life style and diet than to aging itself. In summary, none of the presented alterations is severe enough to cause the disease, but all of them increase the risk of pathology and thus pave the way for the disease even in healthy elderly subjects.

  9. Data driven analysis of rain events: feature extraction, clustering, microphysical /macro physical relationship

    Science.gov (United States)

    Djallel Dilmi, Mohamed; Mallet, Cécile; Barthes, Laurent; Chazottes, Aymeric

    2017-04-01

    The study of rain time series records is mainly carried out using rainfall rate or rain accumulation parameters estimated on a fixed integration time (typically 1 min, 1 hour or 1 day). In this study we used the concept of rain event. In fact, the discrete and intermittent natures of rain processes make the definition of some features inadequate when defined on a fixed duration. Long integration times (hour, day) lead to mix rainy and clear air periods in the same sample. Small integration time (seconds, minutes) will lead to noisy data with a great sensibility to detector characteristics. The analysis on the whole rain event instead of individual short duration samples of a fixed duration allows to clarify relationships between features, in particular between macro physical and microphysical ones. This approach allows suppressing the intra-event variability partly due to measurement uncertainties and allows focusing on physical processes. An algorithm based on Genetic Algorithm (GA) and Self Organising Maps (SOM) is developed to obtain a parsimonious characterisation of rain events using a minimal set of variables. The use of self-organizing map (SOM) is justified by the fact that it allows to map a high dimensional data space in a two-dimensional space while preserving as much as possible the initial space topology in an unsupervised way. The obtained SOM allows providing the dependencies between variables and consequently removing redundant variables leading to a minimal subset of only five features (the event duration, the rain rate peak, the rain event depth, the event rain rate standard deviation and the absolute rain rate variation of order 0.5). To confirm relevance of the five selected features the corresponding SOM is analyzed. This analysis shows clearly the existence of relationships between features. It also shows the independence of the inter-event time (IETp) feature or the weak dependence of the Dry percentage in event (Dd%e) feature. This confirms

  10. Cine Club - Special Event

    CERN Document Server

    Cine Club

    2017-01-01

    Special event on Thursday 4 May 2017 at 18:30 CERN Council Chamber In collaboration with the CERN Running Club and the Women In Technology initiative, the CERN CineClub is happy to announce the screening of the film Free to Run Directed by Pierre Morath Switzerland, 2016, 99 minutes Today, all anybody needs to run is the determination and a pair of the right shoes. But just fifty years ago, running was viewed almost exclusively as the domain of elite male athletes who competed on tracks. With insight and propulsive energy, director Pierre Morath traces running's rise to the 1960s, examining how the liberation movements and newfound sense of personal freedom that defined the era took the sport out of the stadiums and onto the streets, and how legends like Steve Prefontaine, Fred Lebow, and Kathrine Switzer redefined running as a populist phenomenon. Original version French; English subtitles. http://freetorun.ch/ Come along to watch the film and learn more about the history of popular races and amat...

  11. Acidification of lake water due to drought

    Science.gov (United States)

    Mosley, L. M.; Zammit, B.; Jolley, A. M.; Barnett, L.

    2014-04-01

    Droughts are predicted to increase in many river systems due to increased demand on water resources and climate variability. A severe drought in the Murray-Darling Basin of Australia from 2007 to 2009 resulted in unprecedented declines in water levels in the Lower Lakes (Ramsar-listed ecosystem of international importance) at the end of the river system. The receding water exposed large areas (>200 km2) of sediments on the lake margins. The pyrite (FeS2) in these sediments oxidised and generated high concentrations of acidity. Upon rewetting of the exposed sediments, by rainfall or lake refill, surface water acidification (pH 2-3) occurred in several locations (total area of 21.7 km2). High concentrations of dissolved metals (Al, As, Co, Cr, Cu, Fe, Mn, Ni, Zn), which greatly exceeded aquatic ecosystem protection guidelines, were mobilised in the acidic conditions. In many areas neutralisation of the surface water acidity occurred naturally during lake refill, but aerial limestone dosing was required in two areas to assist in restoring alkalinity. However acidity persists in the submerged lake sediment and groundwater several years after surface water neutralisation. The surface water acidification proved costly to manage and improved water management in the Murray-Darling Basin is required to prevent similar events occurring in the future.

  12. Event trigger identification for biomedical events extraction using domain knowledge.

    Science.gov (United States)

    Zhou, Deyu; Zhong, Dayou; He, Yulan

    2014-06-01

    In molecular biology, molecular events describe observable alterations of biomolecules, such as binding of proteins or RNA production. These events might be responsible for drug reactions or development of certain diseases. As such, biomedical event extraction, the process of automatically detecting description of molecular interactions in research articles, attracted substantial research interest recently. Event trigger identification, detecting the words describing the event types, is a crucial and prerequisite step in the pipeline process of biomedical event extraction. Taking the event types as classes, event trigger identification can be viewed as a classification task. For each word in a sentence, a trained classifier predicts whether the word corresponds to an event type and which event type based on the context features. Therefore, a well-designed feature set with a good level of discrimination and generalization is crucial for the performance of event trigger identification. In this article, we propose a novel framework for event trigger identification. In particular, we learn biomedical domain knowledge from a large text corpus built from Medline and embed it into word features using neural language modeling. The embedded features are then combined with the syntactic and semantic context features using the multiple kernel learning method. The combined feature set is used for training the event trigger classifier. Experimental results on the golden standard corpus show that >2.5% improvement on F-score is achieved by the proposed framework when compared with the state-of-the-art approach, demonstrating the effectiveness of the proposed framework. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Onychomycosis due to opportunistic molds.

    Science.gov (United States)

    Martínez-Herrera, Erick Obed; Arroyo-Camarena, Stefanie; Tejada-García, Diana Luz; Porras-López, Carlos Francisco; Arenas, Roberto

    2015-01-01

    Onychomycosis are caused by dermatophytes and Candida, but rarely by non- dermatophyte molds. These opportunistic agents are filamentous fungi found as soil and plant pathogens. To determine the frequency of opportunistic molds in onychomycosis. A retrospective analysis of 4,220 cases with onychomycosis, diagnosed in a 39-month period at the Institute of Dermatology and Skin surgery "Prof. Dr. Fernando A. Cordero C." in Guatemala City, and confirmed with a positive KOH test and culture. 32 cases (0.76%) of onychomycosis caused by opportunistic molds were confirmed. The most affected age group ranged from 41 to 65 years (15 patients, 46.9%) and females were more commonly affected (21 cases, 65.6%) than males. Lateral and distal subungual onychomycosis (OSD-L) was detected in 20 cases (62.5%). The microscopic examination with KOH showed filaments in 19 cases (59.4%), dermatophytoma in 9 cases (28.1%), spores in 2 cases (6.25%), and filaments and spores in 2 cases (6.25%). Etiologic agents: Aspergillus sp., 11 cases (34.4%); Scopulariopsis brevicaulis, 8 cases (25.0%); Cladosporium sp., 3 cases (9.4%); Acremonium sp., 2 cases (6.25%); Paecilomyces sp., 2 cases (6.25%); Tritirachium oryzae, 2 cases (6.25%); Fusarium sp., Phialophora sp., Rhizopus sp. and Alternaria alternate, 1 case (3.1%) each. We found onychomycosis by opportunistic molds in 0.76% of the cases and DLSO was present in 62.5%. The most frequent isolated etiological agents were: Aspergillus sp. and Scopulariopsis brevicaulis.

  14. Onychomycosis due to opportunistic molds*

    Science.gov (United States)

    Martínez-Herrera, Erick Obed; Arroyo-Camarena, Stefanie; Tejada-García, Diana Luz; Porras-López, Carlos Francisco; Arenas, Roberto

    2015-01-01

    BACKGROUND: Onychomycosis are caused by dermatophytes and Candida, but rarely by non- dermatophyte molds. These opportunistic agents are filamentous fungi found as soil and plant pathogens. OBJECTIVES: To determine the frequency of opportunistic molds in onychomycosis. METHODS: A retrospective analysis of 4,220 cases with onychomycosis, diagnosed in a 39-month period at the Institute of Dermatology and Skin surgery "Prof. Dr. Fernando A. Cordero C." in Guatemala City, and confirmed with a positive KOH test and culture. RESULTS: 32 cases (0.76%) of onychomycosis caused by opportunistic molds were confirmed. The most affected age group ranged from 41 to 65 years (15 patients, 46.9%) and females were more commonly affected (21 cases, 65.6%) than males. Lateral and distal subungual onychomycosis (OSD-L) was detected in 20 cases (62.5%). The microscopic examination with KOH showed filaments in 19 cases (59.4%), dermatophytoma in 9 cases (28.1%), spores in 2 cases (6.25%), and filaments and spores in 2 cases (6.25%). Etiologic agents: Aspergillus sp., 11 cases (34.4%); Scopulariopsis brevicaulis, 8 cases (25.0%); Cladosporium sp., 3 cases (9.4%); Acremonium sp., 2 cases (6.25%); Paecilomyces sp., 2 cases (6.25%); Tritirachium oryzae, 2 cases (6.25%); Fusarium sp., Phialophora sp., Rhizopus sp. and Alternaria alternate, 1 case (3.1%) each. CONCLUSIONS: We found onychomycosis by opportunistic molds in 0.76% of the cases and DLSO was present in 62.5%. The most frequent isolated etiological agents were: Aspergillus sp. and Scopulariopsis brevicaulis. PMID:26131862

  15. Prospective coding in event representation.

    Science.gov (United States)

    Schütz-Bosbach, Simone; Prinz, Wolfgang

    2007-06-01

    A perceived event such as a visual stimulus in the external world and a to-be-produced event such as an intentional action are subserved by event representations. Event representations do not only contain information about present states but also about past and future states. Here we focus on the role of representing future states in event perception and generation (i.e., prospective coding). Relevant theoretical issues and paradigms are discussed. We suggest that the predictive power of the motor system may be exploited for prospective coding not only in producing but also in perceiving events. Predicting is more advantageous than simply reacting. Perceptual prediction allows us to select appropriate responses ahead of the realization of an (anticipated) event and therefore, it is indispensable to flexibly and timely adapt to new situations and thus, successfully interact with our physical and social environment.

  16. Semantic Event Correlation Using Ontologies

    Science.gov (United States)

    Moser, Thomas; Roth, Heinz; Rozsnyai, Szabolcs; Mordinyi, Richard; Biffl, Stefan

    Complex event processing (CEP) is a software architecture paradigm that aims at low latency, high throughput, and quick adaptability of applications for supporting and improving event-driven business processes. Events sensed in real time are the basic information units on which CEP applications operate and react in self-contained decision cycles based on defined processing logic and rules. Event correlation is necessary to relate events gathered from various sources for detecting patterns and situations of interest in the business context. Unfortunately, event correlation has been limited to syntactically identical attribute values instead of addressing semantically equivalent attribute meanings. Semantic equivalence is particularly relevant if events come from organizations that use different terminologies for common concepts.

  17. The Braunsbach Flashflood of May 29, 2016: A forensic analysis of the meteorological origin and the hydrological development an extreme hydro-meteorological event

    Science.gov (United States)

    Bronstert, Axel; Ankit, Agarwal; Berry, Boessenkool; Madlen, Fischer; Maik, Heistermann; Lisei, Köhn-Reich; Thomas, Moran; Dadiyorto, Wendi

    2017-04-01

    The flash-flood at 29th May 2016 in the vicinity of the village of Braunsbach in Southwestern Germany, State of Baden-Wuerttemberg, has been a particularly concise event of the floods occurring in southern Germany at the end of May / early June 2016. This extreme event was triggered by a convective high intensity rain storm, causing extreme discharge rates and subsequent debris flow in the local creek. This led to severe flooding of the village with immense damages. Besides its extreme nature, the event is characterized by very local and short term scales, i.e. the catchment of the creek covers an area of only six km2 and the whole event lasted only two hours. This contribution presents a retrospective analysis with regard to meteorology and hydrology to obtain a quantitative assessment of the governing processes and their development. We term this a "forensic analysis" because due to the very local and sudden feature of this flashflood event, the processes cannot be directly measured during the event and/or at the site. Instead, they need to be reconstructed and estimated after the event from a variety of rather different information sources and "soft" data. Using these types of post event observations and analysis, we aim at obtaining a rather comprehensive picture of the event and its consequences. Regarding rainfall, both station data from the surroundings of the catchment and radar data from the German Weather Service were analyzed, including the analysis of different errors types and dynamic features of the convective system. The flood hydrograph, including the maximum discharge rate during the event, was estimated by three different approaches, which were compared to obtain an idea of the associated uncertainty. The overall results of this forensic analysis show that it was a very rare rainfall event with extreme rainfall intensities, e.g. return period exceeding 100 years. Catalyzed by catchment properties, this lead to extreme runoff, severe soil erosion

  18. Tolerability of sibutramine during a 6-week treatment period in high-risk patients with cardiovascular disease and/or diabetes: a preliminary analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial.

    Science.gov (United States)

    Maggioni, Aldo P; Caterson, Ian; Coutinho, Walmir; Finer, Nick; Gaal, Luc Van; Sharma, Arya M; Torp-Pedersen, Christian; Bacher, Peter; Shepherd, Gillian; Sun, Rui; James, Philip

    2008-11-01

    Uncertainties about the cardiovascular safety of sibutramine led to the SCOUT trial that is investigating sibutramine plus weight management in high-risk, overweight/obese patients. A 6-week lead-in period during which all patients received sibutramine permitted an initial assessment of tolerability. A total of 10,742 patients received sibutramine and 3.1% of these discontinued due to an adverse event; issues affecting more than 10 patients were drug intolerance, headache, insomnia, nausea, dry mouth, and constipation-, tachycardia-, and hypertension-related events. Serious adverse events, most commonly associated with the System Organ Class, Cardiac disorders, were reported by 2.7% of patients; however, the majority was not considered sibutramine-related. Adverse events relating to high blood pressure and/or pulse rate, whether reported as adverse events leading to discontinuation, or serious adverse events were reported by less than 0.2% of patients. No serious or individual events leading to discontinuation occurred in more than 25 patients. There were 15 (0.1%) deaths; 10 were attributed to a cardiovascular cause. Discontinuations for adverse events were lower than anticipated. Serious adverse events generally reflected sibutramine's known pharmacology or were related to cardiac disorders already present in this high-risk population. When compared with epidemiological data, overall mortality rate was low and sibutramine was well tolerated in this mainly off-label population. No new safety issues were detected.

  19. Long-period clocks from short-period oscillators

    Science.gov (United States)

    Labavić, Darka; Meyer-Ortmanns, Hildegard

    2017-08-01

    We analyze repulsively coupled Kuramoto oscillators, which are exposed to a distribution of natural frequencies. This source of disorder leads to closed orbits of repetitive temporary patterns of phase-locked motion, providing clocks on macroscopic time scales. The periods can be orders of magnitude longer than the periods of individual oscillators. By construction, the attractor space is quite rich. This may cause long transients until the deterministic trajectories find their stationary orbits. The smaller the width of the distribution about the common natural frequency, the longer are the emerging time scales on average. Among the long-period orbits, we find self-similar sequences of temporary phase-locked motion on different time scales. The ratio of time scales is determined by the ratio of widths of the distributions. The results illustrate a mechanism for how simple systems can provide rather flexible dynamics, with a variety of periods even without external entrainment.

  20. Optical Periodicity Analysis of 3C 446 using Period04

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... All the data of the blazar 3C446 at 8, 4.8, 14 and 22 GHz, presented in publications from 1977 to 2006, have been compiled to generate light curves. The light curves show violent activity of 3C446. Using Period04 analysis method, we have found that there is a period of 7.2 yr, which is consistent with the ...

  1. Statistical Analysis of Loss of Offsite Power Events

    Directory of Open Access Journals (Sweden)

    Andrija Volkanovski

    2016-01-01

    Full Text Available This paper presents the results of the statistical analysis of the loss of offsite power events (LOOP registered in four reviewed databases. The reviewed databases include the IRSN (Institut de Radioprotection et de Sûreté Nucléaire SAPIDE database and the GRS (Gesellschaft für Anlagen- und Reaktorsicherheit mbH VERA database reviewed over the period from 1992 to 2011. The US NRC (Nuclear Regulatory Commission Licensee Event Reports (LERs database and the IAEA International Reporting System (IRS database were screened for relevant events registered over the period from 1990 to 2013. The number of LOOP events in each year in the analysed period and mode of operation are assessed during the screening. The LOOP frequencies obtained for the French and German nuclear power plants (NPPs during critical operation are of the same order of magnitude with the plant related events as a dominant contributor. A frequency of one LOOP event per shutdown year is obtained for German NPPs in shutdown mode of operation. For the US NPPs, the obtained LOOP frequency for critical and shutdown mode is comparable to the one assessed in NUREG/CR-6890. Decreasing trend is obtained for the LOOP events registered in three databases (IRSN, GRS, and NRC.

  2. Transportation planning for planned special events

    Science.gov (United States)

    2011-05-01

    Unique among planned special event activities are those events that carry the National Special Security Event (NSSE) designation. NSSEs occur with some frequency, with 35 of these events held between September 1998 and February 2010. These events inc...

  3. Otomycosis due to filamentous fungi.

    Science.gov (United States)

    García-Agudo, Lidia; Aznar-Marín, Pilar; Galán-Sánchez, Fátima; García-Martos, Pedro; Marín-Casanova, Pilar; Rodríguez-Iglesias, Manuel

    2011-10-01

    Otomycosis is common throughout the world but barely studied in Spain. Our objective was to determine the microbiological and epidemiological characteristics of this pathology in Cadiz (Spain) between 2005 and 2010. Samples from patients with suspicion of otomycosis underwent a direct microscopic examination and culture on different media for fungi and bacteria. Mycological cultures were incubated at 30°C for at least seven days. Identification of fungi was based on colonial morphology and microscopic examination of fungal structure. From a total of 2,633 samples, microbial growth was present in 1,375 (52.2%) and fungal isolation in 390 (28.4%). We identified 228 yeasts and 184 filamentous fungi (13.4% of positive cultures and 47.2% of otomycosis), associated with yeasts in 22 cases (5.6%). The most frequent species were Aspergillus flavus (42.4%), A. niger (35.9%), A. fumigatus (12.5%), A. candidus (7.1%), A. terreus (1.6%), and Paecilomyces variotii (0.5%). Infection was predominant in men (54.9%) and patients beyond 55 years old (46.8%). The most common clinical symptoms were itching (98.9%), otalgia (59.3%), and hypoacusis (56.0%). Fall season reported the lowest number of cases (20.1%). Incidence of otomycosis and fungi producing otomycosis vary within the distinct geographical areas. In Cadiz, this infection is endemic due to warm temperatures, high humidity, sea bathing, and wind, which contributes to disseminate the conidia. Despite Aspergillus niger has been reported as the main causative agent, A. flavus is predominant in Cadiz. Although infection is usually detected in warm months, we observed a homogeneous occurrence of otomycosis in almost all the seasons.

  4. Old Dogs Learning New Tricks: Neuroplasticity beyond the Juvenile Period

    Science.gov (United States)

    Lillard, Angeline S.; Erisir, Alev

    2011-01-01

    Twenty years ago, the prevalent view in Psychology was that although learning and the formation of new memories are lifelong occurrences, the neural changes associated with these events were all in the existing receptors. No new neural hardware, from synapses to neurons, was thought to appear after a protracted period early in life. In the past 20…

  5. Life-threatening events during endurance sports: is heat stroke more prevalent than arrhythmic death?

    Science.gov (United States)

    Yankelson, Lior; Sadeh, Ben; Gershovitz, Liron; Werthein, Julieta; Heller, Karin; Halpern, Pinchas; Halkin, Amir; Adler, Arnon; Steinvil, Arie; Viskin, Sami

    2014-08-05

    Two important causes of sudden death during endurance races are arrhythmic death and heat stroke. However, "arrhythmic death" has caught practically all the attention of the medical community whereas the importance of heat stroke is less appreciated. The study sought to determine what percentage of life-threatening events during endurance races are due to heat stroke or cardiac causes. This retrospective study examined all the long distance popular races that took place in Tel Aviv from March 2007 to November 2013. The number of athletes at risk was known. The number of athletes developing serious sport-related events and requiring hospitalization was known. Life-threatening events were those requiring mechanical ventilation and hospitalization in intensive care units. Overall, 137,580 runners participated in long distance races during the study period. There were only 2 serious cardiac events (1 myocardial infarction and 1 hypotensive supraventricular tachyarrhythmia), neither of which were fatal or life threatening. In contrast, there were 21 serious cases of heat stroke, including 2 that were fatal and 12 that were life threatening. One of the heat stroke fatalities presented with cardiac arrest without previous warning. In our cohort of athletes participating in endurance sports, for every serious cardiac adverse event, there were 10 serious events related to heat stroke. One of the heat stroke-related fatalities presented with unheralded cardiac arrest. Our results put in a different perspective the ongoing debate about the role of pre-participation electrocardiographic screening for the prevention of sudden death in athletes. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  6. The "New Climate" New Atmospheric Events and "New Climate Risks": The case of Morocco

    Science.gov (United States)

    Karrouk, M. S.

    2015-12-01

    Since the end of last century, qualified meteorological events of "exceptional" causing floods have ceased to occur in Morocco and elsewhere, with a recurrence increasingly high, prompting to wonder about the "new" mode of climate's hydrothermal functioning inducing torrential rains, as well as its effect on the environment and societies.The latest event is the disaster of November 2014 flooding in southern Morocco, which is due especially to the non usual rains return.Weather conditions were marked by enhanced Meridian Atmospheric Circulation (MAC), characterized by persistent high temperatures during the autumn period in Morocco, mainly south of the Atlas, combined by the intrusion of a cold drop in the beginning of the event on 11.17.2014, and straightforward installation of a planetary valley across the Moroccan coast on 11.24.2014, which has evolved into storm (Xandra) in which depression has reached the surprising value of 975 hPa on 11.28.2014.Human and material damage caused by this flood are impressive: people died, roads, bridges and crops have been destroyed, overwhelmed dams. It has been a catastrophe.This event and others like it (Mohammedia 2002, Tangier 2008, Gharb 2009-2010, Casablanca 2010), must be considered as references for the simulation of future situations, and integration into development plans on future.This communication aims to identify the processes and conditions that have generated these events causing floods, the "exceptional" characteristics of recorded rainfall, the spatial and temporal distribution of events. Those floods affect the whole country, especially low areas, foothills and the mouths of rivers. There are the most vulnerable locations mainly on the autumn which is the most exposed to torrential rainfall season !! ... Etc.

  7. Seepage patterns of Diuron in a ditch bed during a sequence of flood events

    Energy Technology Data Exchange (ETDEWEB)

    Dages, C., E-mail: cecile.dages@supagro.inra.fr; Samouëlian, A.; Negro, S.; Storck, V.; Huttel, O.; Voltz, M.

    2015-12-15

    Although ditches limit surface water contamination, groundwater recharge through ditches in Mediterranean catchments may result in groundwater contamination. We analysed the dynamics of pesticide percolation in ditches by conducting an original lab experiment that mimicked the successive percolation processes that occur during a flood season. Nine successive percolation events were operated on an undisturbed soil column collected from a ditch bed. The infiltrating water was doped with {sup 14}C-Diuron at concentrations that were chosen to decrease between the events so as to correspond to values observed during actual flood events. The water and solute fluxes were monitored during each event, and the final extractable and non-extractable Diuron residues in the column were determined. Two main observations were made. First, a high leaching potential was observed through the ditch bed over a succession of infiltrating flood events, with 58.9% of the infiltrated Diuron and its metabolites leaching. Second, compared with the contamination of surface water circulating in the ditches, the contamination of seepage water exhibited smaller peak values and persisted much longer because of the desorption of Diuron residues stored in the ditch bed. Thus, ditches serve as buffering zones between surface and groundwater. However, compared with field plots, ditches appear to be a preferential location for the percolation of pesticides into groundwater at the catchment scale. - Highlights: • Diuron percolation in a ditch bed during flood events was mimicked in a column setup. • Diuron percolation can represent up to 50% of the infiltrated Diuron. • The ditch bed exhibits a high buffering capacity due to its high sorption properties. • Contamination period of percolation water lasts longer than that of infiltrating water. • Diuron residues stored in ditch bed move deeper than in field topsoils.

  8. Bidirectional infrasonic ducts associated with sudden stratospheric warming events

    NARCIS (Netherlands)

    Assink, J.D.; Waxler, R.; Smets, P.S.M.; Evers, L.G.

    2014-01-01

    In January 2011, the state of the polar vortex in the midlatitudes changed significantly due to a minor sudden stratospheric warming event. As a result, a bidirectional duct for infrasound propagation developed in the middle atmosphere that persisted for 2 weeks. The ducts were due to two zonal wind

  9. Evolution and precession of accretion disk in tidal disruption events

    Directory of Open Access Journals (Sweden)

    Matzner C.D.

    2012-12-01

    Full Text Available In a supermassive black hole (BH tidal disruption event (TDE, the tidally disrupted star feeds the BH via an accretion disk. Most often it is assumed that the accretion rate history, hence the emission light curve, tracks the rate at which new debris mass falls back onto the disk, notably the t−5/3 power law. But this is not the case when the disk evolution due to viscous spreading - the driving force for accretion - is carefully considered. We construct a simple analytical model that comprehensively describes the accretion rate history across 4 different phases of the disk evolution, in the presence of mass fallback and disk wind loss. Accretion rate evolves differently in those phases which are governed by how the disk heat energy is carried away, early on by advection and later by radiation. The accretion rate can decline as steeply as t−5/3 only if copious disk wind loss is present during the early advection-cooled phase. Later, the accretion rate history is t−8/7 or shallower. These have great implications on the TDE flare light curve. A TDE accretion disk is most likely misaligned with the equatorial plane of the spinning BH. Moreover, in the TDE the accretion rate is super- or near-Eddington thus the disk is geometrically thick, for which case the BH’s frame dragging effect may cause the disk precess as a solid body, which may manifest itself as quasi-periodic signal in the TDE light curve. Our disk evolution model predicts the disk precession period increases with time, typically as ∝ t. The results are applied to the recently jetted TDE flare Swift transient J1644 + 57 which shows numerous, quasi-periodic dips in its long-term X-ray light curve. As the current TDE sample increases, the identification of the disk precession signature provides a unique way of measuring BH spin and studying BH accretion physics.

  10. The incubation period of kuru.

    Science.gov (United States)

    Huillard d'Aignaux, Jérôme N; Cousens, Simon N; Maccario, Jean; Costagliola, Dominique; Alpers, Michael P; Smith, Peter G; Alpérovitch, Annick

    2002-07-01

    Kuru is a transmissible spongiform encephalopathy that was identified in Papua New Guinea in the late 1950s. Several thousand cases of the disease occurred during a period of several decades. Epidemiologic investigations implicated ritual endocannibalistic funeral feasts as the likely route through which the infectious agent was spread. We estimated the incubation period distribution of kuru using a back-calculation model and explored the relation among sex, age at infection, and incubation period. Key assumptions in the model were that the number of new kuru infections in a year was proportional to the number of kuru cases dying that year, and that the epidemic arose from a single case of sporadic Creutzfeldt-Jakob Disease occurring around 1900. The mean incubation period of kuru was estimated at between 10.3 and 13.2 years. Point estimates of the 90th percentile ranged from 21.1 to 27.0 years. The incubation period in females was estimated to be shorter than that in males. The shortest incubation periods were estimated in adult women, who may have been exposed to the largest doses of infectious material. Our findings suggest that the relatively young age of cases of variant Creutzfeldt-Jakob disease probably reflects increased levels of exposure in young people, rather than age-dependency in the incubation period.

  11. Rising cyclin-CDK levels order cell cycle events.

    Directory of Open Access Journals (Sweden)

    Catherine Oikonomou

    Full Text Available Diverse mitotic events can be triggered in the correct order and time by a single cyclin-CDK. A single regulator could confer order and timing on multiple events if later events require higher cyclin-CDK than earlier events, so that gradually rising cyclin-CDK levels can sequentially trigger responsive events: the "quantitative model" of ordering.This 'quantitative model' makes predictions for the effect of locking cyclin at fixed levels for a protracted period: at low cyclin levels, early events should occur rapidly, while late events should be slow, defective, or highly variable (depending on threshold mechanism. We titrated the budding yeast mitotic cyclin Clb2 within its endogenous expression range to a stable, fixed level and measured time to occurrence of three mitotic events: growth depolarization, spindle formation, and spindle elongation, as a function of fixed Clb2 level. These events require increasingly more Clb2 according to their normal order of occurrence. Events occur efficiently and with low variability at fixed Clb2 levels similar to those observed when the events normally occur. A second prediction of the model is that increasing the rate of cyclin accumulation should globally advance timing of all events. Moderate (<2-fold overexpression of Clb2 accelerates all events of mitosis, resulting in consistently rapid sequential cell cycles. However, this moderate overexpression also causes a significant frequency of premature mitoses leading to inviability, suggesting that Clb2 expression level is optimized to balance the fitness costs of variability and catastrophe.We conclude that mitotic events are regulated by discrete cyclin-CDK thresholds. These thresholds are sequentially triggered as cyclin increases, yielding reliable order and timing. In many biological processes a graded input must be translated into discrete outputs. In such systems, expression of the central regulator is likely to be tuned to an optimum level, as we

  12. Frequency of adverse events after vaccination with different vaccinia strains.

    Directory of Open Access Journals (Sweden)

    Mirjam Kretzschmar

    2006-08-01

    Full Text Available BACKGROUND: Large quantities of smallpox vaccine have been stockpiled to protect entire nations against a possible reintroduction of smallpox. Planning for an appropriate use of these stockpiled vaccines in response to a smallpox outbreak requires a rational assessment of the risks of vaccination-related adverse events, compared to the risk of contracting an infection. Although considerable effort has been made to understand the dynamics of smallpox transmission in modern societies, little attention has been paid to estimating the frequency of adverse events due to smallpox vaccination. Studies exploring the consequences of smallpox vaccination strategies have commonly used a frequency of approximately one death per million vaccinations, which is based on a study of vaccination with the New York City Board of Health (NYCBH strain of vaccinia virus. However, a multitude of historical studies of smallpox vaccination with other vaccinia strains suggest that there are strain-related differences in the frequency of adverse events after vaccination. Because many countries have stockpiled vaccine based on the Lister strain of vaccinia virus, a quantitative evaluation of the adverse effects of such vaccines is essential for emergency response planning. We conducted a systematic review and statistical analysis of historical data concerning vaccination against smallpox with different strains of vaccinia virus. METHODS AND FINDINGS: We analyzed historical vaccination data extracted from the literature. We extracted data on the frequency of postvaccinal encephalitis and death with respect to vaccinia strain and age of vaccinees. Using a hierarchical Bayesian approach for meta-analysis, we estimated the expected frequencies of postvaccinal encephalitis and death with respect to age at vaccination for smallpox vaccines based on the NYCBH and Lister vaccinia strains. We found large heterogeneity between findings from different studies and a time-period effect

  13. Events and mega events: leisure and business in tourism

    Directory of Open Access Journals (Sweden)

    Ricardo Alexandre Paiva

    2015-12-01

    Full Text Available The promotion of events and mega events mobilizes at the same time, in a concatenated way or not, leisure and business practices, which are captured by the tourism industry as a stimulus for the reproduction of capitalism, by the amount of other activities which raise (primary, secondary and tertiary , placing the architecture and the city as protagonists in contemporary urban development. In this sense, the article analyzes the articulation of events and mega events to the provision of architecture and urban infrastructure, as well as the construction of the tourist image of the places, motivated by leisure and business activities. The methodological procedures have theoretical and exploratory character and have multidisciplinary intentions. This will be discussed, in a historical perspective, the concepts of leisure and business activities that raise as moving or traveling; next it will be delimited similarities and differences between tourism events and business tourism, entering after the analysis of the distinctions between events and mega events, highlighting the complexity and the role of mega-events as a major symptom of globalization; finally it will be presented the spatial scale developments in architecture and the city in the realization of (mega events, as well as its impact on the city's image. As a synthesis, it is important to notice that spatial developments business tourism, events and mega events are manifested in various scales and with different levels of complexity, revealing the strengths and / or weaknesses of the places. The urban planning, architecture and urbanism are important objects of knowledge and spatial intervention to ensure infrastructure and urban and architectural structures appropriate for events, which should be sensitive to the demands of tourists and host communities.

  14. Mercury's rotation axis and period

    Science.gov (United States)

    Klaasen, K. P.

    1976-01-01

    Recent measurements made from high-resolution Mariner 10 photography of the planet Mercury yield a rotation period of 58.6461 + or 0.005 days, in excellent agreement with the period required for a precise 2/3 resonance with its orbital period (58.6462 days). The axis of rotation of the planet was calculated to be offset about 2 deg from the perpendicular to its orbital plane within a 50% probability error ellipse of + or - 2.6 deg by + or - 6.5 deg. Dynamical considerations make it most likely that the true displacement from the orbit normal is less than 1 deg.

  15. The Periodic Table in Croatia

    Directory of Open Access Journals (Sweden)

    Raos, N.

    2011-12-01

    Full Text Available The Croatian (Yugoslav Academy of Sciences and Arts was the first academy to elect D. I. Mendeleev as its honorary member (1882, whereas the periodic table of the elements has been taught regularly at the Zagreb University since 1888. The early interest of Croatian chemists in the periodic table should be attributed primarily to their pan-Slavic attitude, particularly as proof that Slavic people were able to produce "their own Newtons" (M. V. Lomonosov and D. I. Mendeleev. Such enthusiastic views, however, did not help in analyzing the contribution of Mendeleev and other scientists to the discovery and development of the periodic table of the elements.

  16. The use of Kolmogorov-Smirnov test in event-by-event analysis

    Energy Technology Data Exchange (ETDEWEB)

    Tomasik, Boris [Univerzita Mateja Bela, Tajovskeho 40, 97401 Banska Bystrica (Slovakia); Czech Technical University in Prague, FNSPE, Brehova 11, 11519 Prague (Czech Republic); Melo, Ivan [Zilinska Univerzita, Univerzitna 1, 01026 Zilina (Slovakia); Torrieri, Giorgio [FIAS, Goethe-Universitaet, Ruth-Moufang-Str. 1, 60438 Frankfurt (Germany); Vogel, Sascha; Bleicher, Marcus [Institut fuer Theoretische Physik, Goethe-Universitaet, Max-von-Laue-Str. 1, 60438 Frankfurt (Germany)

    2009-11-01

    We propose to use the Kolmogorov-Smirnov test to uncover non-statistical differences between events created in heavy ion collisions within the same centrality class. The advantage of the method over other approaches which are currently in use, is that it is sensitive to any difference between the events and is not restricted to simple moments of the distribution of hadrons. The particular application examined here is the identification of the fireball decay due to spinodal fragmentation and/or sudden rise of the bulk viscosity.

  17. Cost estimation of cardiovascular disease events in the US.

    Science.gov (United States)

    O'Sullivan, Amy K; Rubin, Jaime; Nyambose, Joshua; Kuznik, Andreas; Cohen, David J; Thompson, David

    2011-08-01

    In this study, we developed cost prediction equations that facilitate estimation of the costs of various cardiovascular events for patients of specific demographic and clinical characteristics over varying time horizons. We used administrative claims data and generalized linear models to develop cost prediction equations for selected cardiovascular events, including myocardial infarction (MI), angina, strokes and revascularization procedures. Separate equations were estimated for patients with events and for their propensity score-matched controls. Attributable costs were estimated on a monthly basis for the first 36 months after each event and annually thereafter, with differences in survival between cases and controls factored into the longitudinal cost calculations. The regression models were used to estimate event costs ($US, year 2007 values) for the 'average' patient in each event group, over various time periods ranging from 1 month to lifetime. When the equations are run for the average patient in each event group, attributable costs of each event in the acute phase (i.e. first 3 years) are substantial (e.g. MI $US 73 300; hospitalization for angina $US 36 000; non-fatal haemorrhagic stroke $US 71 600). Furthermore, for most events, cumulative costs remain substantially higher among cases than among controls over the remaining lifetime of the patients. This study provides updated estimates of medical care costs of cardiovascular events among a managed care population over various time horizons. Results suggest that the economic burden of cardiovascular disease is substantial, both in the acute phase as well as over the longer term.

  18. Coastal Flooding Hazards due to storm surges and subsidence

    DEFF Research Database (Denmark)

    Sørensen, Carlo; Knudsen, Per; Andersen, Ole B.

    Flooding hazard and risk mapping are major topics in low-lying coastal areas before even considering the adverse effects of sea level rise (SLR) due to climate change. While permanent inundation may be a prevalent issue, more often floods related to extreme events (storm surges) have the largest...... damage potential.Challenges are amplified in some areas due to subsidence from natural and/or anthropogenic causes. Subsidence of even a few mm/y may over time greatly impair the safety against flooding of coastal communities and must be accounted for in order to accomplish the economically most viable...

  19. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks of the two electron pairs are colored red, the clusters in the LAr calorimeter are colored darkgreen.

  20. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  1. Event display of a H -> 4mu candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4mu candidate event with m(4l) = 124.1 (125.1) GeV without (with) Z mass constraint. The masses of the lepton pairs are 86.3 GeV and 31.6 GeV. The event was recorded by ATLAS on 10-Jun-2012, 13:24:31 CEST in run number 204769 as event number 71902630. Muon tracks are colored red. The inset on the right-hand side shows a zoom into the tracking detector. The inset on top shows a zoom into the vertex region, indicating that the 4 muons originate from the same primary vertex.

  2. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. Zoom into the tracking detector and the LAr calorimeter where its detailed structure is highlighted. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  3. Event display of a H -> 4e candidate event

    CERN Multimedia

    ATLAS, Collaboration

    2012-01-01

    Event display of a H -> 4e candidate event with m(4l) = 124.5 (124.6) GeV without (with) Z mass constraint. The masses of the lepton pairs are 70.6 GeV and 44.7 GeV. The event was recorded by ATLAS on 18-May-2012, 20:28:11 CEST in run number 203602 as event number 82614360. Zoom into the tracking detector. The tracks and clusters of the two electron pairs are colored red and blue, respectively.

  4. Analysis of the spatio-temporal variability of extreme hydro-meteorological events over Germany

    Science.gov (United States)

    Samaniego-Eguiguren, L. E.; Coskun, M.; Kumar, R.; Zink, M.; Attinger, S.

    2010-12-01

    Extreme hydro-meteorological events are the major cause of Great Natural Disasters according to the United Nations. In 2008 overall losses due to flood and drought related events amounted to US\\~570 bn (Munich RE). Discharge regimes of river basins are expected to be altered due to possible effects of climate change. For planning and water resources management, it is fundamental to estimate the probability of occurrence of extreme hydro-meteorological events as well as its intensity. Predictions of climatic variables such as temperature and precipitation are currently done with GCM and RCM for global and regional scales, respectively. A fundamental research question at the moment is: are current RCMs able to reproduce the spatio-temporal variability of extreme events that were observed during the past decades? If not, what kind of bias exist in those data sets and how can these simulations be made useful for hydrologic projections? In this study we analyze these questions using the most recent comprehensive RCM data sets available from the ENSEMBLES project over whole Germany for the period from 1961 to 2000. During this period all RCMs were driven by ERA-40 reanalysis at spatial resolutions of 25 km and 50 km. Among the analyzed variables were the time evolution and the areal extend of various extreme statistics such as precipitation and temperature above and below a threshold value, maxiμm and miniμm air temperatures, maxiμm daily precipitation in summer. Additionally the spatial correlation structure of daily precipitation and the spatial pattern of a wetness index for each synoptic circulation pattern were also considered. These indices were compared with their respective ones obtained from observations of more than five thousand meteorological stations over Germany. Preliminary results indicate that the various RCMs were able to reproduce in some cases and for some indices the observed spatial patterns. The magnitudes of extreme event indices (Fig. 1) were

  5. Within-Event and Between-Events Ground Motion Variability from Earthquake Rupture Scenarios

    Science.gov (United States)

    Crempien, Jorge G. F.; Archuleta, Ralph J.

    2017-09-01

    Measurement of ground motion variability is essential to estimate seismic hazard. Over-estimation of variability can lead to extremely high annual hazard estimates of ground motion exceedance. We explore different parameters that affect the variability of ground motion such as the spatial correlations of kinematic rupture parameters on a finite fault and the corner frequency of the moment-rate spectra. To quantify the variability of ground motion, we simulate kinematic rupture scenarios on several vertical strike-slip faults and compute ground motion using the representation theorem. In particular, for the entire suite of rupture scenarios, we quantify the within-event and the between-events ground motion variability of peak ground acceleration (PGA) and response spectra at several periods, at 40 stations—all approximately at an equal distance of 20 and 50 km from the fault. Both within-event and between-events ground motion variability increase when the slip correlation length on the fault increases. The probability density functions of ground motion tend to truncate at a finite value when the correlation length of slip decreases on the fault, therefore, we do not observe any long-tail distribution of peak ground acceleration when performing several rupture simulations for small correlation lengths. Finally, for a correlation length of 6 km, the within-event and between-events PGA log-normal standard deviations are 0.58 and 0.19, respectively, values slightly smaller than those reported by Boore et al. (Earthq Spectra, 30(3):1057-1085, 2014). The between-events standard deviation is consistently smaller than the within-event for all correlations lengths, a feature that agrees with recent ground motion prediction equations.

  6. Comparative study on the ionospheric response to minor and major sudden stratospheric events in the Brazilian equatorial and low latitudes

    Science.gov (United States)

    Fagundes, Paulo Roberto; Kavutarapu, Venkatesh; Gil Pillat, Valdir; Vieira, Francisco

    2016-07-01

    The Total electron Content (TEC), derivate from GPS, becomes one of the most powerful techniques to study the space-time ionospheric (F-region) electrodynamics, during the quiet and disturbed periods. The number of GPS stations in Brazil increased significantly during the last few years; currently more than 100 GPS stations are in operation over the Brazilian region. The GPS-TEC values are derived using the differential delay technique from the dual frequency measurements at L1 and L2 frequencies over the considered locations at equatorial and low latitudes. The present study investigates the ionospheric total electron content (GPS-TEC) response in the Southern Hemisphere equatorial and low latitudes, due to major and minor sudden stratospheric warming (SSW) events, which took place during 2009 and 2012. During both the SSW events, the TEC values are depleted to the order of 20-30% all over the Brazil from equator to beyond Equatorial Ionization Anomaly (EIA) regions. In addition, the EIA were suppressed during the SSW events for several days. However, the TEC depletion and EIA suppression lasted for a longer period during SSW-2012 when compared with the SSW-2009; despite the SSW-2012 is considerd as a minor event.

  7. Model-based assessment of the role of human-induced climate change in the 2005 Caribbean coral bleaching event

    Energy Technology Data Exchange (ETDEWEB)

    Donner, S.D. [Princeton Univ., NJ (United States). Woodrow Wilson School of Public and International Affairs; Knutson, T.R. [National Oceanic and Atmospheric Administration, Princeton, NJ (United States). Geophysical Fluid Dynamics Lab.; Oppenheimer, M. [Princeton Univ., NJ (United States). Dept. of Geosciences

    2007-03-27

    Episodes of mass coral bleaching around the world in recent decades have been attributed to periods of anomalously warm ocean temperatures. In 2005, the sea surface temperature (SST) anomaly in the tropical North Atlantic that may have contributed to the strong hurricane season caused widespread coral bleaching in the Eastern Caribbean. Here, the authors use two global climate models to evaluate the contribution of natural climate variability and anthropogenic forcing to the thermal stress that caused the 2005 coral bleaching event. Historical temperature data and simulations for the 1870-2000 period show that the observed warming in the region is unlikely to be due to unforced climate variability alone. Simulation of background climate variability suggests that anthropogenic warming may have increased the probability of occurrence of significant thermal stress events for corals in this region by an order of magnitude. Under scenarios of future greenhouse gas emissions, mass coral bleaching in the Eastern Caribbean may become a biannual event in 20-30 years. However, if corals and their symbionts can adapt by 1-1.5{sup o}C, such mass bleaching events may not begin to recur at potentially harmful intervals until the latter half of the century. The delay could enable more time to alter the path of greenhouse gas emissions, although long-term 'committed warming' even after stabilization of atmospheric CO{sub 2} levels may still represent an additional long-term threat to corals.

  8. Measuring Scars of Periodic Orbits

    CERN Document Server

    Kaplan, L

    1999-01-01

    The phenomenon of periodic orbit scarring of eigenstates of classically chaotic systems is attracting increasing attention. Scarring is one of the most important ``corrections'' to the ideal random eigenstates suggested by random matrix theory. This paper discusses measures of scars and in so doing also tries to clarify the concepts and effects of eigenfunction scarring. We propose a new, universal scar measure which takes into account an entire periodic orbit and the linearized dynamics in its vicinity. This measure is tuned to pick out those structures which are induced in quantum eigenstates by unstable periodic orbits and their manifolds. It gives enhanced scarring strength as measured by eigenstate overlaps and inverse participation ratios, especially for longer orbits. We also discuss off-resonance scars which appear naturally on either side of an unstable periodic orbit.

  9. Nonlinear waves in periodic media

    OpenAIRE

    Ketcheson, David; Luna, Manuel Quezada de

    2015-01-01

    This poster advertises several recent theoretical developments the computational modeling of nonlinear waves in periodic materials, by the Numerical Mathematics Group at KAUST.  The papers referenced in the poster are linked to below.

  10. Periodic progress report, 6 months

    DEFF Research Database (Denmark)

    Juhl, Thomas Winther; Nielsen, Jakob Skov

    This is the first progress report of the BriteEuram project named "High Power Laser Cutting for Heavy Industry" ("Powercut"). The report contains a summary of the objectives of the first period, an overview of the technical progress, a comparison between the planed and the accomplished work......, a description of the planned activities for the next period, and last comments on management and coordination....

  11. Vibration Control in Periodic Structures

    DEFF Research Database (Denmark)

    Høgsberg, Jan Becker

    2017-01-01

    Within the framework of periodic structures, the calibration of RL shunted piezoelectric inclusions is investigated with respect to maximum damping of a particular wave form. A finite element setting is assumed, with local shunted inclusions inside the unit cell. The effect of the shunts is repre....... The presentation contains dispersion diagrams and vibration amplitude curves for the optimally calibrated RL shunt system in a 1-D periodic structure with local piezoelectric inclusions....

  12. Large gradual solar energetic particle events

    Directory of Open Access Journals (Sweden)

    Mihir Desai

    2016-09-01

    Full Text Available Abstract Solar energetic particles, or SEPs, from suprathermal (few keV up to relativistic ( $$\\sim $$ ∼ few GeV energies are accelerated near the Sun in at least two ways: (1 by magnetic reconnection-driven processes during solar flares resulting in impulsive SEPs, and (2 at fast coronal-mass-ejection-driven shock waves that produce large gradual SEP events. Large gradual SEP events are of particular interest because the accompanying high-energy ( $${>}10$$ > 10 s MeV protons pose serious radiation threats to human explorers living and working beyond low-Earth orbit and to technological assets such as communications and scientific satellites in space. However, a complete understanding of these large SEP events has eluded us primarily because their properties, as observed in Earth orbit, are smeared due to mixing and contributions from many important physical effects. This paper provides a comprehensive review of the current state of knowledge of these important phenomena, and summarizes some of the key questions that will be addressed by two upcoming missions—NASA’s Solar Probe Plus and ESA’s Solar Orbiter. Both of these missions are designed to directly and repeatedly sample the near-Sun environments where interplanetary scattering and transport effects are significantly reduced, allowing us to discriminate between different acceleration sites and mechanisms and to isolate the contributions of numerous physical processes occurring during large SEP events.

  13. Cardiac tamponade due to hypothyroidism: a case cluster report ...

    African Journals Online (AJOL)

    Cardiac tamponade due to hypothyroidism: a case cluster report. Ankia Coetzee, Charles Kyriakakis, Chris Greyling, B.H. Ascott-Evans. Abstract. This study reports on three patients who were seen at Tygerberg Hospital within a short period of six months, with a new diagnosis of biochemically severe primary hypothyroidism ...

  14. 29 CFR 95.73 - Collection of amounts due.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Collection of amounts due. 95.73 Section 95.73 Labor Office of the Secretary of Labor GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND... constitute a debt to the Federal Government. If not paid within a reasonable period after the demand for...

  15. Changes in winter warming events in the Nordic Arctic Region

    Science.gov (United States)

    Vikhamar-Schuler, Dagrun; Isaksen, Ketil; Haugen, Jan Erik; Bjerke, Jarle Werner; Tømmervik, Hans

    2015-04-01

    In recent years winter warming events are frequently reported from Arctic areas. Extraordinarily warm weather episodes, occasionally combined with intense rainfall, cause severe ecological disturbance and great challenges for Arctic infrastructure. For example, the formation of ground ice due to winter rain or melting prevents reindeer from grazing, leads to vegetation browning, and impacts soil temperatures. The infrastructure may be affected by avalanches and floods resulting from intense snowmelt. The aim of our analysis is to study changes in warm spells during winter in the Nordic Arctic Region, here defined as the regions in Norway, Sweden and Finland north of the Arctic circle (66.5°N), including the Arctic islands Svalbard and Jan Mayen. Within this study area we have selected the longest available high quality observation series with daily temperature and precipitation. For studying future climate we use available regionally downscaled scenarios. We analyse three time periods: 1) the past 50-100 years, 2) the present (last 15 years, 2000-2014) and 3) the future (next 50-100 years). We define an extended winter season (October-April) and further divide it into three subseasons: 1) Early winter (October and November), 2) Mid-winter (December, January and February) and 3) Late-winter (March and April). We identify warm spells using two different classification criteria: a) days with temperature above 0°C (the melting temperature); and b) days with temperature in excess of the 90th percentile of the 1985-2014 temperature for each subseason. Both wet and dry warm spells are analysed. We compare the results for the mainland stations (maritime and inland stations) with the Arctic islands. All stations have very high frequency of warm weather events in the period 1930-1940s and for the last 15 years (2000-2014). For the most recent period the largest increase in number of warm spells are observed at the northernmost stations. We also find a continuation of this

  16. [Validation of an adverse event reporting system in primary care].

    Science.gov (United States)

    de Lourdes Rojas-Armadillo, María; Jiménez-Báez, María Valeria; Chávez-Hernández, María Margarita; González-Fondón, Araceli

    2016-01-01

    Patient safety is a priority issue in health systems, due to the damage costs, institutional weakening, lack of credibility, and frustration on those who committed an error that resulted in an adverse event. There is no standardized instrument for recording, reporting, and analyzing sentinel or adverse events (AE) in primary care. Our aim was to design and validate a surveillance system for recording sentinel events, adverse events and near miss incidents in primary care. We made a review of systems for recording and reporting adverse events in primary care. Then, we proposed an instrument to record these events, and register faults in the structure and process, in primary health care units in the Instituto Mexicano del Seguro Social. We showed VENCER-MF format to 35 subjects. Out of them, 100% identified a failure in care process, 90% recorded a sentinel event, 85% identified the cause of this event, 75% of them suggested some measures for avoiding the recurrence of adverse events. We used a Cronbach's alpha of 0.6, p=0.03. The instrument VENCER-MF has a good consistency for the identification of adverse events.

  17. Effect of the surface geology on strong ground motions due to the 2016 Central Tottori Earthquake, Japan

    Science.gov (United States)

    Kagawa, Takao; Noguchi, Tatsuya; Yoshida, Shohei; Yamamoto, Shinji

    2017-08-01

    On October 21, 2016, an earthquake with Japan Meteorological Agency (JMA) magnitude 6.6 hit the central part of Tottori Prefecture, Japan. This paper demonstrates two notable effects of the surface geology on strong ground motions due to the earthquake. One is a predominant period issue observed over a large area. A seismic intensity of 6 lower on the JMA scale was registered at three sites in the disaster area. However, the peak ground acceleration ranged from 0.3 to 1.4 G at the three sites because of the varying peak periods of observed strong ground motions. The spectral properties of the observations also reflect the damage around the sites. Three-component microtremors were observed in the area; the predominant ground period distributions based on horizontal to vertical spectral ratios were provided by the authors. The peak periods of the strong motion records agree well with predominant periods estimated from microtremor observations at a rather hard site; however, the predominant periods of the microtremors are slightly shorter than those of the main shock at the other two soft sites. We checked the nonlinear effect at the sites by comparing the site responses to small events and the main shock. The peak periods of the main shock were longer than those of the weak motions at the sites. This phenomenon indicates a nonlinear site effect due to large ground motions caused by the main shock. A horizontal component of the accelerogram showed rather pulsating swings that indicate cyclic mobility behavior, especially at a site close to a pond shore; ground subsidence of 20 cm was observed around the site. The peak periods of weak motions agree well with those of the microtremor observations. This implies an important issue that the predominant periods estimated by microtremors are not sufficient to estimate the effect of surface geology for disaster mitigation. We have to estimate the predominant periods under large ground motions considering the nonlinear site

  18. Period proliferation in periodic states in cyclically sheared jammed solids

    Science.gov (United States)

    Lavrentovich, Maxim O.; Liu, Andrea J.; Nagel, Sidney R.

    2017-08-01

    Athermal disordered systems can exhibit a remarkable response to an applied oscillatory shear: After a relatively few shearing cycles, the system falls into a configuration that had already been visited in a previous cycle. After this point the system repeats its dynamics periodically despite undergoing many particle rearrangements during each cycle. We study the behavior of orbits as we approach the jamming point in simulations of jammed particles subject to oscillatory shear at fixed pressure and zero temperature. As the pressure is lowered, we find that it becomes more common for the system to find periodic states where it takes multiple cycles before returning to a previously visited state. Thus, there is a proliferation of longer periods as the jamming point is approached.

  19. Watershed and longitudinal monitoring events

    Science.gov (United States)

    Harold Harbert; Steven Blackburn

    2016-01-01

    Georgia Adopt-A-Stream partners annually with many organizations, universities and watershed groups to conduct sampling events with volunteers at a watershed level. These monitoring events range from one-day snapshots to week-long paddle trips. One-day sampling events, also called “Blitzs,” River Adventures and River Rendezvous, generally target 20-50 sites within a...

  20. Extinction Events Can Accelerate Evolution

    OpenAIRE

    Joel Lehman; Risto Miikkulainen

    2015-01-01

    Extinction events impact the trajectory of biological evolution significantly. They are often viewed as upheavals to the evolutionary process. In contrast, this paper supports the hypothesis that although they are unpredictably destructive, extinction events may in the long term accelerate evolution by increasing evolvability. In particular, if extinction events extinguish indiscriminately many ways of life, indirectly they may select for the ability to expand rapidly through vacated niches. ...