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Sample records for evaluation wise study

  1. A case study on evaluations of improvements implemented by WISE projects in the Philippines.

    Science.gov (United States)

    Takeyama, Hidemaro; Itani, Toru; Tachi, Norihide; Takanishi, Toshimasa; Inoue, Tatsuki; Murata, Kensaburo; Ebara, Takeshi; Batino, Jose Maria

    2006-01-01

    The aim of this study is to evaluate the effects of work improvements in small enterprises (WISE) on workloads and productivity, and managers' satisfaction with those projects. Participating in this study from 1994 to 1996 were 9 small enterprises, 3 metal industries, 1 car parts manufacturing, 1 garment manufacturing, 1 food processing, and a few others. Upon visiting these worksites, we carried out interviews on the implemented WISE improvements and made objective evaluations of their effect on workloads and productivity. Reductions in physical workloads were found in 4 of 6 enterprises where that factor was estimated. Productivity in most of the enterprises increased after WISE improvements. Managers' subjective satisfaction with WISE activity ranged between 50-80% on each technical item. More than 50 percent of managers came to understand the necessity of workers' involvement and understanding of the activities in order to sustain activity for improvement. WISE activity can exert a beneficial influence on workload and productivity. Most of the managers were satisfied with the results. It is presumed that follow-up visits with objective estimation will provide both managers and workers with encouragement to maintain their efforts.

  2. Climate wise case study compendium: Report 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-01

    This case study compendium is one of several Climate Wise tools available to help interested companies identify cost-effective options. Climate Wise, a private-public partnership program, is a key Federal initiative to return greenhouse gas emissions to 1990 levels by 2000.

  3. Combining psychosocial data to improve prediction of cardiovascular disease risk factors and events:: The NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study

    Science.gov (United States)

    Whittaker, Kerry S.; Krantz, David S.; Rutledge, Thomas; Johnson, B. Delia; Wawrzyniak, Andrew J.; Bittner, Vera; Eastwood, Jo-Ann; Eteiba, Wafia; Cornell, Carol E.; Pepine, Carl J.; Vido, Diane A.; Handberg, Eileen; Merz, C. Noel Bairey

    2012-01-01

    Background There is overlap among psychosocial variables associated with cardiovascular disease (CVD), and utility of combining psychosocial variables as risk markers for understanding CVD is largely unknown. Methods Women (n=493) in the NHLBI Women's Ischemia Syndrome Evaluation (WISE) Study were evaluated. The predictive value for CVD events was determined for multivariate combination of Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Social Network Index (SNI), and Cook-Medley hostility (Ho) scales. Principal components analysis of psychosocial scales revealed composite psychosocial risk markers, and their relationships to CVD events and risk factors were assessed. Results In a multivariate model, the block of SNI, Hostile Affect, STAI and BDI predicted CVD events (χ2[6]=27.8, ppsychosocial variables. Multivariate combination of psychosocial risk markers predicts CVD events; derived psychosocial factors were associated with CVD risk factors but not events. Measuring common and unique variance among psychosocial variables may be useful for understanding and predicting CVD. PMID:22434916

  4. TIMI frame count and adverse events in women with no obstructive coronary disease: a pilot study from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE).

    Science.gov (United States)

    Petersen, John W; Johnson, B Delia; Kip, Kevin E; Anderson, R David; Handberg, Eileen M; Sharaf, Barry; Mehta, Puja K; Kelsey, Sheryl F; Merz, C Noel Bairey; Pepine, Carl J

    2014-01-01

    TIMI frame count (TFC) predicts outcomes in patients with obstructive coronary artery disease (CAD); it remains unclear whether TFC predicts outcomes in patients without obstructive CAD. TFC was determined in a sample of women with no obstructive CAD enrolled in the Women's Ischemia Syndrome Evaluation (WISE) study. Because TFC is known to be higher in the left anterior descending artery (LAD), TFC determined in the LAD was divided by 1.7 to provide a corrected TFC (cTFC). A total of 298 women, with angiograms suitable for TFC analysis and long-term (6-10 year) follow up data, were included in this sub-study. Their age was 55±11 years, most were white (86%), half had a history of smoking, and half had a history of hypertension. Higher resting cTFC was associated with a higher rate of hospitalization for angina (34% in women with a cTFC >35, 15% in women with a cTFC ≤35, P<0.001). cTFC provided independent prediction of hospitalization for angina after adjusting for many baseline characteristics. In this cohort, resting cTFC was not predictive of major events (myocardial infarction, heart failure, stroke, or all-cause death), cardiovascular events, all-cause mortality, or cardiovascular mortality. In women with signs and symptoms of ischemia but no obstructive CAD, resting cTFC provides independent prediction of hospitalization for angina. Larger studies are required to determine if resting TFC is predictive of major events in patients without obstructive coronary artery disease.

  5. Prospective, blinded exploratory evaluation of the PlayWisely program in children with autism spectrum disorder.

    Science.gov (United States)

    Kern, Janet K; Garver, Carolyn R; Mehta, Jyutika A; Hannan, Patricia A; Bakken, Liz E; Vidaud, Aileen M; Abraham, Judie; Daoud, Yahya

    2013-06-01

    The purpose of the study was to explore a low-cost intervention that targets an increasingly common developmental disorder. The study was a blinded, exploratory evaluation of the PlayWisely program on autism symptoms and essential learning foundation skills (attention, recognition, and memory skills) in children with a diagnosis of autism, autism spectrum disorder (ASD), pervasive developmental disorder - not otherwise specified (PDD-NOS), and Asperger syndrome (AS). Eighteen children, 1 to 10 years of age, were evaluated using the Childhood Autism Rating Scale, Second Edition (CARS2); the PlayWisely Interactive Test of Attention, Recognition, and Memory Skills; Autism Treatment Evaluation Checklist (ATEC), and the Modified Checklist for Autism in Toddlers (M-CHAT). There were significant treatment effects for the PlayWisely measure on the Yellow Sets that examine recognition; Purple Sets that examine brain region agility and early memory skills; Blue Sets that examine phonemic awareness and recognition; and for the Total Sets, with a similar trend toward improvement in the Green Sets that examine perception and Red Sets that examine attention. No other measures reached statistical significance. The results suggest that PlayWisely can improve recognition, brain region agility, phonemic awareness, letter recognition, and early memory skills in ASD. It was observed by the parents, coaches, and study investigators that the children who were less than 3 years of age showed improvements in autism symptoms; however, the group was too small to reach statistical significance. Future studies are needed to see if this intervention can mitigate autism symptoms in very young children with ASD.

  6. Delivering the WISE (Whole Systems Informing Self-Management Engagement training package in primary care: learning from formative evaluation

    Directory of Open Access Journals (Sweden)

    Protheroe Joanne

    2010-01-01

    Full Text Available Abstract Background The WISE (Whole System Informing Self-management Engagement approach encompasses creating, finding, and implementing appropriate self-care support for people with long-term conditions. A training package for primary care to introduce the approach was developed and underwent formative evaluation. This entailed exploring the acceptability of the WISE approach and its effectiveness in changing communication within consultations. The study aimed to refine the patient, practitioner, and patient level components of the WISE approach and translate the principles of WISE into an operational intervention deliverable through National Health Service training methods. Methods Normalisation Process Theory provided a framework for development of the intervention. Practices were recruited from an inner city Primary Care Trust in NW England. All practice staff were expected to attend two afternoon training sessions. The training sessions were observed by members of the training team. Post-training audio recordings of consultations from each general practitioner and nurse in the practices were transcribed and read to provide a narrative overview of the incorporation of WISE skills and tools into consultations. Face-to-face semi-structured interviews were conducted with staff post-training. Results Two practices out of 14 deemed eligible agreed to take part. Each practice attended two sessions, although a third session on consultation skills training was needed for one practice. Fifty-four post-training consultations were recorded from 15 clinicians. Two members of staff were interviewed at each practice. Significant elements of the training form and methods of delivery fitted contemporary practice. There were logistical problems in getting a whole practice to attend both sessions, and administrative staff founds some sections irrelevant. Clinicians reported problems incorporating some of the tools developed for WISE, and this was confirmed in

  7. Delivering the WISE (Whole Systems Informing Self-Management Engagement) training package in primary care: learning from formative evaluation.

    Science.gov (United States)

    Kennedy, Anne; Chew-Graham, Carolyn; Blakeman, Thomas; Bowen, Andrew; Gardner, Caroline; Protheroe, Joanne; Rogers, Anne; Gask, Linda

    2010-01-29

    The WISE (Whole System Informing Self-management Engagement) approach encompasses creating, finding, and implementing appropriate self-care support for people with long-term conditions. A training package for primary care to introduce the approach was developed and underwent formative evaluation. This entailed exploring the acceptability of the WISE approach and its effectiveness in changing communication within consultations. The study aimed to refine the patient, practitioner, and patient level components of the WISE approach and translate the principles of WISE into an operational intervention deliverable through National Health Service training methods. Normalisation Process Theory provided a framework for development of the intervention. Practices were recruited from an inner city Primary Care Trust in NW England. All practice staff were expected to attend two afternoon training sessions. The training sessions were observed by members of the training team. Post-training audio recordings of consultations from each general practitioner and nurse in the practices were transcribed and read to provide a narrative overview of the incorporation of WISE skills and tools into consultations. Face-to-face semi-structured interviews were conducted with staff post-training. Two practices out of 14 deemed eligible agreed to take part. Each practice attended two sessions, although a third session on consultation skills training was needed for one practice. Fifty-four post-training consultations were recorded from 15 clinicians. Two members of staff were interviewed at each practice. Significant elements of the training form and methods of delivery fitted contemporary practice. There were logistical problems in getting a whole practice to attend both sessions, and administrative staff founds some sections irrelevant. Clinicians reported problems incorporating some of the tools developed for WISE, and this was confirmed in the overview of consultations, with limited overt use

  8. Psychosocial Factors Versus Single Predictors: A Factor Analytic Approach to Cardiovascular Outcomes in The Women’s Ischemia Syndrome Evaluation (WISE) Study

    Science.gov (United States)

    2010-02-18

    the larger muscular arteries. When these lesion become advanced they can result in ischemia of the heart, brain, or extremities, which can lead to...more women than men experience “atypical” symptoms of a cardiovascular event. Women may report dyspnoea, nausea, abdominal pain, fatigue and atypical...heart disease in men: population based case-control study. Bmj , 316(7146), 1714-1719. Horsten, M., Mittleman, M. A., Wamala, S. P., Schenck

  9. Brachial artery constriction during brachial artery reactivity testing predicts major adverse clinical outcomes in women with suspected myocardial ischemia: results from the NHLBI-sponsored women's ischemia Syndrome Evaluation (WISE Study.

    Directory of Open Access Journals (Sweden)

    Tara L Sedlak

    Full Text Available Limited brachial artery (BA flow-mediated dilation during brachial artery reactivity testing (BART has been linked to increased cardiovascular risk. We report on the phenomenon of BA constriction (BAC following hyperemia.To determine whether BAC predicts adverse CV outcomes and/or mortality in the women's ischemic Syndrome Evaluation Study (WISE. Further, as a secondary objective we sought to determine the risk factors associated with BAC.We performed BART on 377 women with chest pain referred for coronary angiography and followed for a median of 9.5 years. Forearm ischemia was induced with 4 minutes occlusion by a cuff placed distal to the BA and inflated to 40mm Hg > systolic pressure. BAC was defined as >4.8% artery constriction following release of the cuff. The main outcome was major adverse events (MACE including all-cause mortality, non-fatal MI, non-fatal stroke, or hospitalization for heart failure.BA diameter change ranged from -20.6% to +44.9%, and 41 (11% women experienced BAC. Obstructive CAD and traditional CAD risk factors were not predictive of BAC. Overall, 39% of women with BAC experienced MACE vs. 22% without BAC (p=0.004. In multivariate Cox proportional hazards regression, BAC was a significant independent predictor of MACE (p=0.018 when adjusting for obstructive CAD and traditional risk factors.BAC predicts almost double the risk for major adverse events compared to patients without BAC. This risk was not accounted for by CAD or traditional risk factors. The novel risk marker of BAC requires further investigation in women.

  10. D-WISE: Diabetes Web-Centric Information and Support Environment: conceptual specification and proposed evaluation.

    Science.gov (United States)

    Abidi, Samina; Vallis, Michael; Raza Abidi, Syed Sibte; Piccinini-Vallis, Helena; Imran, Syed Ali

    2014-06-01

    support services that use logic-based reasoning algorithms to utilize the knowledge encoded within the diabetes management ontology to assist physicians by recommending patient-specific diabetes-management interventions and behaviour-change strategies; C) a mobile diabetes self-management application to engage and educate diabetes patients to self-manage their condition in a home-based setting while working in concert with their family physicians. We have been successful in creating and conducting a usability assessment of the physician decision support tool. These results will be published once the patient self- management application has been evaluated. D-WISE will be evaluated through pilot studies measuring 1) the usability of the e-Health interventions; and 2) the impact of the interventions on patients' behaviour changes and diabetes control. Copyright © 2014 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  11. Evaluation of users' satisfaction on pedestrian facilities using pair-wise comparison approach

    Science.gov (United States)

    Zainol, R.; Ahmad, F.; Nordin, N. A.; Aripin, A. W. M.

    2014-02-01

    Global climate change issues demand people of the world to change the way they live today. Thus, current cities need to be redeveloped towards less use of carbon in their day to day operations. Pedestrianized environment is one of the approaches used in reducing carbon foot print in cities. Heritage cities are the first to be looked into since they were built in the era in which motorized vehicles were minimal. Therefore, the research explores users' satisfaction on assessment of physical attributes of pedestrianization in Melaka Historical City, a UNESCO World Heritage Site. It aims to examine users' satisfaction on pedestrian facilities provided within the study area using pair wise questionnaire comparison approach. A survey of 200 respondents using random sampling was conducted in six different sites namely Jonker Street, Church Street, Kota Street, Goldsmith Street, Merdeka Street to Taming Sari Tower and Merdeka Street to River Cruise terminal. The survey consists of an assessment tool based on a nine-point scale of users' satisfaction level of pathway properties, zebra pedestrian crossing, street furniture, personal safety, adjacent to traffic flow, aesthetic and amenities. Analytical hierarchical process (AHP) was used to avoid any biasness in analyzing the data collected. Findings show that Merdeka Street to Taming Sari Tower as the street that scores the highest satisfaction level that fulfils all the required needs of a pedestrianized environment. Similar assessment elements can be used to evaluate existing streets in other cities and these criteria should also be used in planning for future cities.

  12. Evaluation of a support worker role, within a nurse delegation and supervision model, for provision of medicines support for older people living at home: the Workforce Innovation for Safe and Effective (WISE) Medicines Care study.

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    Lee, Cik Yin; Beanland, Christine; Goeman, Dianne; Johnson, Ann; Thorn, Juliet; Koch, Susan; Elliott, Rohan A

    2015-10-06

    Support with managing medicines at home is a common reason for older people to receive community nursing services. With population ageing and projected nurse shortages, reliance on nurses may not be sustainable. We developed and tested a new workforce model: 'Workforce Innovation for Safe and Effective (WISE) Medicines Care', which enabled nurses to delegate medicines support home visits for low-risk clients to support workers (known as community care aides [CCAs]). Primary study aims were to assess whether the model increased the number of medicines support home visits conducted by CCAs, explore nurses', CCAs' and consumers' experiences with the CCAs' expanded role, and identify enablers and barriers to delegation of medicines support. A prospective before-after mixed-methods study was conducted within a community nursing service that employed a small number of CCAs. The CCAs' main role prior to the WISE Medicines Care model was personal care, with a very limited role in medicines support. CCAs received training in medicines support, and nurses received training in assessment, delegation and supervision. Home visit data over two three-month periods were compared. Focus groups and interviews were conducted with purposive samples of nurses (n = 27), CCAs (n = 7) and consumers (n = 28). Medicines support visits by CCAs increased from 43/16,863 (0.25 %) to 714/21,552 (3.3 %) (p Nurses reported mostly positive experiences, and high levels of trust and confidence in CCAs. They reported that delegating to CCAs sometimes eliminated the need for duplicate nurse and CCA visits (for people requiring personal care plus medicines support) and enabled them to visit people with more complex needs. CCAs enjoyed their expanded role and were accepted by clients and/or carers. Nurses and CCAs reported effective communication when medicine-related problems occurred. No medication incidents involving CCAs were reported. Barriers to implementation included the limited

  13. A Study of Locale-Wise Differences in Certain Cognitive and Non-Cognitive Variables

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    Puar, Surjit Singh

    2012-01-01

    The present study has been designed to investigate the locale-wise differences among high school students on the basis of certain cognitive variables like general mental ability and academic achievement and non-cognitive variables such as anxiety, emotional maturity and social maturity. The study was conducted over a sample of 400 (200 boys and…

  14. Bridging the Divide: A Case Study Investigating Digitally-Wise Teacher Perceptions of Middle School Cyberbullying

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    Graves, Tiffany Nicole

    2013-01-01

    The purpose of this qualitative case study was to explore the perceptions of middle school, technologically proficient, or digitally-wise teachers, regarding how they defined, prevented, recognized, and handled incidences of cyberbullying in four middle schools located in Southern Virginia. Data was collected using an open-ended questionnaire,…

  15. A new flow-diverter(the FloWise): In vivo evaluation in an elastase-induced rabbit aneurysm model

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    Kim, Byung Moon; Kim, Dong Joon; Kim, Dong Ik [Severance Hospital, Yonsei University College of Medicine, Seoul (Korea, Republic of)

    2016-02-15

    We aimed to evaluate the efficacy and safety of a newly developed, partially retrievable flow-diverter (the FloWise) in an elastase-induced rabbit aneurysm model. We developed a partially retrievable flow diverter composed of 48 strands of Nitinol and platinum wire. The FloWise is compatible with any microcatheter of 0.027-inch inner diameter, and is retrievable up to 70% deployment. The efficacy and safety of the FloWise were evaluated in the elastase-induced rabbit aneurysm model. The rate of technical success (full coverage of aneurysm neck) and assessment of aneurysm occlusion and stent patency was conducted by angiograms and histologic examinations at the 1-month, 3-month, and 6-month follow-up. The patency of small arterial branches (intercostal or lumbar arteries) covered by the FloWise were also assessed in the 5 subjects. We attempted FloWise insertion in a total of 32 aneurysm models. FloWise placement was successful in 31 subjects (96.9%). Two stents (6.2%) were occluded at the 3-month follow-up, but there was no evidence of in-stent stenosis in other subjects. All stented aneurysms showed progressive occlusion: grade I (complete aneurysm occlusion) in 44.4% and grade II (aneurysm occlusion > 90%) in 55.6% at 1 month; grade I in 90% and II in 10% at 3 months; and grade I in 90% and II in 10% at 6 months. All small arterial branches covered by the FloWise remained patent. A newly developed, partially retrievable flow-diverter seems to be a safe and effective tool of aneurysm occlusion, as evaluated in the rabbit aneurysm model.

  16. Retrospective Case Study in Wise County, Texas, Study of the Potential Impacts of Hydraulic Fracturing on Drinking Water Resources

    Science.gov (United States)

    This report describes the retrospective case study in north central Texas, conducted at three locations in Wise County where both conventional and unconventional gas production occurred in the past. Currently unconventional gas production occurs from the Mississippian-aged Barne...

  17. Choosing Wisely Canada Students and Trainees Advocating for Resource Stewardship (STARS) campaign: a descriptive evaluation.

    Science.gov (United States)

    Cardone, Franco; Cheung, Daphne; Han, Angela; Born, Karen B; Alexander, Lisa; Levinson, Wendy; Wong, Brian M

    2017-12-19

    Resource stewardship is being increasingly recognized as an essential competency for physicians, but medical schools are just beginning to integrate this into education. We describe the evaluation of Choosing Wisely Canada's Students and Trainees Advocating for Resource Stewardship (STARS) campaign, a student-led campaign to advance resource stewardship education in medical schools across Canada. We evaluated the campaign 6 months after its launch, in November 2015. STARS students were administered a telephone survey eliciting a description of the initiatives that they had implemented or planned to implement at their schools to promote resource stewardship, and exploring their perceptions of facilitators of and barriers to successful implementation of their initiatives. We used a mixed-methods approach to analyze and summarize the data. Twenty-seven (82%) of the 33 eligible students representing all 17 medical schools responded. In 14 schools (82%), students led various local activities (e.g., interest groups, campaign weeks) to raise awareness about resource stewardship among medical students and faculty. Students contributed to curriculum change (both planned and implemented) at 10 schools (59%). Thematic analysis revealed key program characteristics that facilitated success (e.g., pan-Canadian student network, local faculty champion) as well as barriers to implementing change (e.g., complex processes to change curriculum, hierarchical nature of medical school). This student-led campaign, with support from local faculty and Choosing Wisely Canada staff, led to awareness-building activities and early curricula change at medical schools across Canada. Future plans will build on the initial momentum created by the STARS campaign to sustain and spread local initiatives. Copyright 2017, Joule Inc. or its licensors.

  18. Evaluation of the Wise Guys Male Responsibility Curriculum: Participant-Control Comparisons

    Science.gov (United States)

    Gruchow, Harvey William; Brown, Roger K.

    2011-01-01

    Background: Although males are often the initiators of teen sexual activity, pregnancy prevention programs generally target females. To address this deficiency, the Wise Guys Male Responsibility Curriculum was developed to be delivered to adolescent males in weekly classroom sessions. Methods: Seventh grade participants (n = 124) in the Wise Guys…

  19. Evaluation of a computerized cognitive behavioural therapy programme, MindWise (2.0), for adults with mild-to-moderate depression and anxiety.

    Science.gov (United States)

    Collins, Sarah; Byrne, Michael; Hawe, James; O'Reilly, Gary

    2017-12-02

    To investigate the acceptability and utility of a newly developed computerized cognitive behavioural therapy (cCBT) programme, MindWise (2.0), for adults attending Irish primary care psychology services. Adult primary care psychology service users across four rural locations in Ireland were invited to participate in this study. A total of 60 service users participated in the MindWise (2.0) treatment group and compared to 22 people in a comparison waiting list control group. Participants completed pre- and post-intervention outcome measures of anxiety, depression, and work/social functioning. At post-intervention, 25 of 60 people in the MindWise (2.0) condition had fully completed the programme and 19 of 22 people in the waiting list condition provided time 2 data. Relative to those in the control group, the MindWise (2.0) participants reported significantly reduced symptoms of anxiety and no change in depression or work/social functioning. The newly developed cCBT programme, MindWise (2.0), resulted in significant improvements on a measure of anxiety and may address some barriers to accessing more traditional face-to-face mental health services for adults in a primary care setting. Further programme development and related research appears both warranted and needed to lower programme drop-out, establish if gains in anxiety management are maintained over time, and support people in a primary care context with depression. There is a growing evidence base that computerized self-help programmes can assist in a stepped-care approach to adult mental health service provision. These programmes require further development to address issues such as high dropout, the development of equally effective transdiagnostic content, and greater effectiveness in the country of origin. This study evaluated the acceptability and utility of a brief online CBT programme for adults referred due to anxiety or low mood to primary care psychology services in the national health service in

  20. Academic physicians' views on low-value services and the choosing wisely campaign: A qualitative study.

    Science.gov (United States)

    Bishop, Tara F; Cea, Meagan; Miranda, Yesenia; Kim, Robert; Lash-Dardia, Meredith; Lee, Jennifer I; Steel, Peter; Goldberg, Jordan; Mechanic, Elaine; Fener, Victoria; Gerber, Linda M

    2017-03-01

    In 2012, the American Board of Internal Medicine (ABIM) Foundation launched a campaign called Choosing Wisely which was intended to start a national dialogue on services that are not medically necessary. More research is needed on the in-depth reasons why doctors overuse low-value services, their views on Choosing Wisely specifically, and ways to help them change their practice patterns. We performed a qualitative study of focus groups with physicians to explore their views on the problem of overuse of low-value services, the reasons why they overuse, and ways that they think could be effective at curbing overuse. Participants were attendings in the fields of emergency medicine, internal medicine, hospital medicine, and cardiology. All physicians felt that overuse of low-value services was a significant problem. Physicians frequently cited that patient expectations drove the use of low-value services and lack of time was the most cited reason why behavior change was difficult. Facilitators that could promote behavior change included decision support through the electronic medical record, motivation to maintain their reputation among their colleagues, internal motivation to be a good doctor, objective data showing their rates of overuse, alignment of institutional goals, and forums to discuss evidence and new research. In focus groups with physicians, we found that physicians perceived that overuse of low-value services was a problem. Participants cited many barriers to behavior change. Methods that help address patient expectations, physician time, and social norms may help physicians reduce their use of low-value services. Copyright © 2017. Published by Elsevier Inc.

  1. Quality of Social Media and Web-Based Information Regarding Inappropriate Nuclear Cardiac Stress Testing and the Choosing Wisely Campaign: A Cross-Sectional Study.

    Science.gov (United States)

    Winchester, David E; Baxter, Diana; Markham, Merry J; Beyth, Rebecca J

    2017-05-04

    The World Wide Web and social media provide the public with access to medical information unlike any other time in human history. However, the quality of content related to cardiac stress testing is not well understood. The aim of our study was to evaluate the quality of content on the Internet relating to the use of cardiac nuclear stress testing and the Choosing Wisely campaign. We searched the World Wide Web, Google Video (including YouTube), and Twitter for information relating to these two topics. Searches were performed using English language terms from a computer in the United States not logged into any personal user accounts. Search results were reviewed for discussion of specific topics including radiation risk, accuracy of testing, alternative testing options, and discouragement of inappropriate test use. We evaluated a total of 348 items of content from our searches. Relevant search results for Choosing Wisely were fewer than for other search terms (45 vs 303). We did not find any content which encouraged inappropriate testing (ie, screening in low risk individuals or testing prior to low risk operations). Content related to Choosing Wisely was more likely to discourage inappropriate testing than search results for other terms (29/45, 64% vs 12/303, 4.0%, odds ratio 43.95, 95% CI 17.6-112.2, Pcampaign.

  2. Outcomes 30 days after ICU admission: the 30DOS study | Wise ...

    African Journals Online (AJOL)

    Robert Wise, Kim de Vasconcellos, David Skinner, Reitze Rodseth, Dean Gopalan, David Muckart, Zohra Banoo, Tashmin Bisseru, Steve Blakemore, Jenine de Meyer, Michael Faurie, Kom Govender, Timothy Hardcastle, Prakash Jeena, Nicky Kalafatis, Kroshlan Kistan, Theroshnie Kisten, Carolyn Lee, Colin Mitchell, ...

  3. Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests.

    Directory of Open Access Journals (Sweden)

    Mattias Frånberg

    2015-09-01

    Full Text Available Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in current analyses. Exhaustive investigations of interactions are typically infeasible because the vast number of possible interactions impose hard statistical and computational challenges. There is, therefore, a need for computationally efficient methods that build on models appropriately capturing interaction. We introduce a new methodology where we augment the interaction hypothesis with a set of simpler hypotheses that are tested, in order of their complexity, against a saturated alternative hypothesis representing interaction. This sequential testing provides an efficient way to reduce the number of non-interacting variant pairs before the final interaction test. We devise two different methods, one that relies on a priori estimated numbers of marginally associated variants to correct for multiple tests, and a second that does this adaptively. We show that our methodology in general has an improved statistical power in comparison to seven other methods, and, using the idea of closed testing, that it controls the family-wise error rate. We apply our methodology to genetic data from the PROCARDIS coronary artery disease case/control cohort and discover three distinct interactions. While analyses on simulated data suggest that the statistical power may suffice for an exhaustive search of all variant pairs in ideal cases, we explore strategies for a priori selecting subsets of variant pairs to test. Our new methodology facilitates identification of new disease-relevant interactions from existing and future genome-wide association data, which may involve genes with previously unknown association to the disease. Moreover, it enables construction of interaction networks that provide a systems biology

  4. Community-wise evaluation of rice beer prepared by some ethnic tribes of Tripura

    Directory of Open Access Journals (Sweden)

    Sushanta Ghosh

    2016-12-01

    Full Text Available Tripura is inhabited by many indigenous communities having unique ethno-socio-cultural lifestyle with age-old rice beer brewing techniques using wild herbs and local rice varieties popularly known as chuwak or zu. The present study is focused on comparative evaluation of brewing methods and nutritional aspects of rice beer among Debbarma, Jamatia, Koloi, and Molsom tribes of Tripura. Sample ingredients and plant species are properly identified before reporting. Rice beer is also prepared in laboratory conditions for comparative studies of qualitative and quantitative aspects. Thirteen different plant species are used by these four tribes for preparation of starter cultures using soaked rice flour. Markhamia stipulate (Wall. Seem. is common to all communities for starter cake preparation. Litsea monopetala (Roxb. Pers. is used by all three communities except Jamatia. The use of Ananus comosus Mill. is common among Debbarma and Jamatia tribes, whereas that of Artocarpus heterophyllus Lam. is common among Molsom and Koloi tribes. However, Aporusa diocia (Roxb. Muell., Combretum indicum (L. DeFilipps., and Citrus sinensis (L. Osbeck. are used only by Debbarma tribe for unique tangy flavor. The physicochemical properties of rice beer varied within tribes for its moisture content, carbohydrate content, reducing sugar, and alcohol percentage. The concentration of alcohol increases with aging and prolonged fermentation. The plants reported here are also reported for having nutritional and medicinal benefits for the metabolic stability in humans, which make the process more prospective for commercialization if a standard for maintaining a quality and associated risk can be determined.

  5. Quality of Social Media and Web-Based Information Regarding Inappropriate Nuclear Cardiac Stress Testing and the Choosing Wisely Campaign: A Cross-Sectional Study

    OpenAIRE

    Winchester, David E.; Baxter, Diana; Markham, Merry Jennifer; Beyth, Rebecca J.

    2017-01-01

    Background The World Wide Web and social media provide the public with access to medical information unlike any other time in human history. However, the quality of content related to cardiac stress testing is not well understood. Objective The aim of our study was to evaluate the quality of content on the Internet relating to the use of cardiac nuclear stress testing and the Choosing Wisely campaign. Methods We searched the World Wide Web, Google Video (including YouTube), and Twitter for in...

  6. A STUDY OF THE DIVERSE T DWARF POPULATION REVEALED BY WISE

    Energy Technology Data Exchange (ETDEWEB)

    Mace, Gregory N.; Wright, Edward L.; McLean, Ian S. [Department of Physics and Astronomy, UCLA, 430 Portola Plaza, Box 951547, Los Angeles, CA 90095-1547 (United States); Davy Kirkpatrick, J.; Gelino, Christopher R.; Griffith, Roger L.; Mix, Katholeen; Beichman, Charles A.; Lowrance, Patrick J. [Infrared Processing and Analysis Center, MS 100-22, California Institute of Technology, Pasadena, CA 91125 (United States); Cushing, Michael C. [Department of Physics and Astronomy, MS 111, University of Toledo, 2801 W. Bancroft St., Toledo, OH 43606-3328 (United States); Skrutskie, Michael F. [Department of Astronomy, University of Virginia, Charlottesville, VA 22904 (United States); Marsh, Kenneth A. [School of Physics and Astronomy, Cardiff University, Cardiff CF24 3AA (United Kingdom); Eisenhardt, Peter R. [NASA Jet Propulsion Laboratory, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Thompson, Maggie A. [Department of Astrophysical Sciences, Princeton University, Peyton Hall, 4 Ivy Lane, Princeton, NJ 08544-1001 (United States); Bailey, Vanessa; Hinz, Philip M.; Knox, Russell P. [Steward Observatory, The University of Arizona, 933 N. Cherry Ave., Tucson, AZ 85721 (United States); Bloom, Joshua S. [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Burgasser, Adam J. [Department of Physics, University of California, San Diego, CA 92093 (United States); Fortney, Jonathan J., E-mail: gmace@astro.ucla.edu [Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA 95064 (United States); and others

    2013-03-01

    We report the discovery of 87 new T dwarfs uncovered with the Wide-field Infrared Survey Explorer (WISE) and 3 brown dwarfs with extremely red near-infrared colors that exhibit characteristics of both L and T dwarfs. Two of the new T dwarfs are likely binaries with L7 {+-} 1 primaries and mid-type T secondaries. In addition, our follow-up program has confirmed 10 previously identified T dwarfs and 4 photometrically selected L and T dwarf candidates in the literature. This sample, along with the previous WISE discoveries, triples the number of known brown dwarfs with spectral types later than T5. Using the WISE All-Sky Source Catalog we present updated color-color and color-type diagrams for all the WISE-discovered T and Y dwarfs. Near-infrared spectra of the new discoveries are presented along with spectral classifications. To accommodate later T dwarfs we have modified the integrated flux method of determining spectral indices to instead use the median flux. Furthermore, a newly defined J-narrow index differentiates the early-type Y dwarfs from late-type T dwarfs based on the J-band continuum slope. The K/J indices for this expanded sample show that 32% of late-type T dwarfs have suppressed K-band flux and are blue relative to the spectral standards, while only 11% are redder than the standards. Comparison of the Y/J and K/J index to models suggests diverse atmospheric conditions and supports the possible re-emergence of clouds after the L/T transition. We also discuss peculiar brown dwarfs and candidates that were found not to be substellar, including two young stellar objects and two active galactic nuclei. The substantial increase in the number of known late-type T dwarfs provides a population that will be used to test models of cold atmospheres and star formation. The coolest WISE-discovered brown dwarfs are the closest of their type and will remain the only sample of their kind for many years to come.

  7. Wise Choices

    DEFF Research Database (Denmark)

    Linder, Stefan; Lyngsie, Jacob; Foss, Nicolai Juul

    2015-01-01

    as managerial criteria. Given that such evaluation takes considerable time, energy, attention, and skill on the part of employees, we propose that firms need to establish a fit between the thoroughness of opportunity appraisal and their reward as well as performance evaluation practices. Evidence from a double......Firms need to invest their scarce resources into the most promising new business opportunities (e.g., new engineering technologies). Yet, the literature on strategic entrepreneurship pays little attention to how, and how thoroughly, firms appraise potential opportunities based on technical as well...

  8. Comparison of PET/CT and whole-mount histopathology sections of the human prostate: a new strategy for voxel-wise evaluation.

    Science.gov (United States)

    Schiller, F; Fechter, T; Zamboglou, C; Chirindel, A; Salman, N; Jilg, C A; Drendel, V; Werner, M; Meyer, P T; Grosu, A-L; Mix, M

    2017-08-17

    Implementation of PET/CT in diagnosis of primary prostate cancer (PCa) requires a profound knowledge about the tracer, preferably from a quantitative evaluation. Direct visual comparison of PET/CT slices to whole prostate sections is hampered by considerable uncertainties from imperfect coregistration and fundamentally different image modalities. In the current study, we present a novel method for advanced voxel-wise comparison of histopathology from excised prostates to pre-surgical PET. Resected prostates from eight patients who underwent PSMA-PET/CT were scanned (ex vivo CT) and thoroughly pathologically prepared. In vivo and ex vivo CT including histopathology were coregistered with three different methods (manual, semi-/automatic). Spatial overlap after CT-based registration was evaluated with dice similarity (DSC). Furthermore, we constructed 3D cancer distribution models from histopathologic information in various slices. Subsequent smoothing reflected the intrinsically limited spatial resolution of PSMA-PET. The resulting histoPET models were used for quantitative analysis of spatial histopathology-PET pattern agreement focusing on p values and coefficients of determination (R 2 ). We examined additional rigid mutual information (MI) coregistration directly based on PSMA-PET and histoPET. Mean DSC for the three different methods (ManReg, ScalFactReg, and DefReg) were 0.79 ± 0.06, 0.82 ± 0.04, and 0.90 ± 0.02, respectively, while quantification of PET-histopathology pattern agreement after CT-based registration revealed R 2 45.7, 43.2, and 41.3% on average with p histopathological preparation allowed sophisticated quantitative analyses showing highly significant correlations between histopathology and (PSMA-)PET. We recommend manual CT-based coregistration followed by a PET-based MI algorithm to overcome limitations of purely CT-based coregistrations for meaningful voxel-wise comparisons between PET and histopathology.

  9. Classification study of WISE infrared sources: identification of candidate asymptotic giant branch stars

    Science.gov (United States)

    Tu, Xun; Wang, Zhong-Xiang

    2013-03-01

    In the Wide-field Infrared Survey Explorer (WISE) all-sky source catalog there are 76 million mid-infrared point sources that were detected in the first three WISE bands and have association with only one 2MASS near-IR source within 3″. We search for their identifications in the SIMBAD database and find 3.2 million identified sources. Based on these known sources, we establish three criteria for selecting candidate asymptotic giant branch (AGB) stars in the Galaxy, which are three defined zones in a color-color diagram, Galactic latitude |b| W3c W3c, we estimate their distances and derive their Galactic distributions. The candidates are generally distributed around the Galactic center uniformly, with 68% (1-σ) of them within approximately 8 kpc. We discuss the idea that optical spectroscopy can be used to verify the C-rich AGB stars in our candidates, and thus a fraction of them (~10%) will be good targets for the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) survey that is planned to start in fall of 2012.

  10. Implementation of a self-management support approach (WISE) across a health system: a process evaluation explaining what did and did not work for organisations, clinicians and patients.

    Science.gov (United States)

    Kennedy, Anne; Rogers, Anne; Chew-Graham, Carolyn; Blakeman, Thomas; Bowen, Robert; Gardner, Caroline; Lee, Victoria; Morris, Rebecca; Protheroe, Joanne

    2014-10-21

    Implementation of long-term condition management interventions rests on the notion of whole systems re-design, where incorporating wider elements of health care systems are integral to embedding effective and integrated solutions. However, most self-management support (SMS) evaluations still focus on particular elements or outcomes of a sub-system. A randomised controlled trial of a SMS intervention (WISE-Whole System Informing Self-management Engagement) implemented in primary care showed no effect on patient-level outcomes. This paper reports on a parallel process evaluation to ascertain influences affecting WISE implementation at patient, clinical and organisational levels. Normalisation Process Theory (NPT) provided a sensitising background and analytical framework. A multi-method approach using surveys and interviews with organisational stakeholders, practice staff and trial participants about impact of training and use of tools developed for WISE. Analysis was sensitised by NPT (coherence, cognitive participation, collective action and reflective monitoring). The aim was to identify what worked and what did not work for who and in what context. Interviews with organisation stakeholders emphasised top-down initiation of WISE by managers who supported innovation in self-management. Staff from 31 practices indicated engagement with training but patchy adoption of WISE tools; SMS was neither prioritised by practices nor fitted with a biomedically focussed ethos, so little effort was invested in WISE techniques. Interviews with 24 patients indicated no awareness of any changes following the training of practice staff; furthermore, they did not view primary care as an appropriate place for SMS. The results contribute to understanding why SMS is not routinely adopted and implemented in primary care. WISE was not embedded because of the perceived lack of relevance and fit to the ethos and existing work. Enacting SMS within primary care practice was not viewed as a

  11. Robust Estimation of Group-wise Cortical Correspondence with an Application to Macaque and Human Neuroimaging Studies

    Directory of Open Access Journals (Sweden)

    Ilwoo eLyu

    2015-06-01

    Full Text Available We present a novel group-wise registration method for cortical correspondence for local cortical thickness analysis in human and non-human primate neuroimaging studies. The proposed method is based on our earlier template based registration that estimates a continuous, smooth deformation field via sulcal curve-constrained registration employing spherical harmonic decomposition of the deformation field. This pairwise registration though results in a well-known template selection bias, which we aim to overcome here via a group-wise approach. We propose the use of an unbiased ensemble entropy minimization following the use of the pairwise registration as an initialization. An individual deformation field is then iteratively updated onto the unbiased average. For the optimization, we use metrics specific for cortical correspondence though all of these are straightforwardly extendable to the generic setting: The first focused on optimizing the correspondence of automatically extracted sulcal landmarks and the second on that of sulcal depth property maps. We further propose a robust entropy metric and a hierarchical optimization by employing spherical harmonic basis orthogonality. We also provide the detailed methodological description of both our earlier work and the proposed method with a set of experiments on a population of human and non-human primate subjects. In the experiment, we have shown that our method achieves superior results on consistency through quantitative and visual comparisons as compared to the existing methods.

  12. A Look into the Association between Life-Wise Syllabus and Teacher Success: A Quantitative Study in an EFL Context

    Directory of Open Access Journals (Sweden)

    Hamid Khosravany Fard

    2015-05-01

    Full Text Available The current study aimed at investigating the relationship between life-wise syllabus- as a new type of syllabus which emerged as the result of recent developments in applied ELT and corresponding to the "education for life"- and teacher success in an EFL context. Life-wise syllabus introduced by Pishghadam in 2011 directed English teachers’ attention to give priority to life issues rather than language in class. These new concepts encourage curriculum development based on life and all of its manifestations which is the core principle of humanistic education. Then teaching should not only comprise mathematics, chemistry, or literature, but also emotions, relationships, attitudes, thinking styles, feelings, and states of mind. Due to the recent emergence of this syllabus and the dearth of research over its effectiveness, this research study was carried out to shed more light on the issue. To this end, 200 teachers- 100 from private sector and 100 from public sector- and their 1771 students were chosen as the participants of the research study from Mashhad and Ghaen cities. In this study, the teachers were given "Life-Responsive Language Teaching beliefs Questionnaire" (hereafter LRLTB, and their students were given the "Characteristics of Successful EFL Teachers Questionnaire" (hereafter CSET. The results of the correlational study indicated that the main variables and also their subscales were highly correlated. The comparison between male and female teachers regarding correlation between variables did not show any significant difference. But the comparison between private and public school teachers in terms of the relationship between the variables displayed that they were more strongly correlated for the latter.

  13. WISE and the Dusty Universe

    Science.gov (United States)

    Benford, Dominic J.

    2010-01-01

    The Wide-field Infrared Survey is a medium class Explorer mission that was launched onl4Dec 2009. WISE should detect hundreds of millions of stars and galaxies, including millions of ULIRGS and QSOs; hundreds of thousands of asteroids; and hundreds of cold brown dwarfs. The telescope cover was ejected on 29 Dec 2009 and the all-sky survey started on 14 Jan 2010. WISE takes more the 7000 framesets per day, with each frameset covering 0.6 square degrees in four bands centered at 3.4, 4.6, 12 and 22 microns. WISE is well-suited to the discovery of brown dwarfs, ultraluminous infrared galaxies, and near-Earth objects. With an angular resolution of 6 arcsecouds at 12 microns, a 5(sigma) point-source sensitivity of around 1 mJy at 12 microns and 6 mJy at 22 microns, and coverage of over 99% of the sky, WISE also provides a powerful database for the study of the dusty ISM in our own galaxy. A preliminary release of WISE data will be made available to the community 6 months after the end of the cryogenic survey, or about May 2011. The final data release will be 11 months later, about April 2012.

  14. Altered Brain Network in Amyotrophic Lateral Sclerosis: A Resting Graph Theory-Based Network Study at Voxel-Wise Level.

    Science.gov (United States)

    Zhou, Chaoyang; Hu, Xiaofei; Hu, Jun; Liang, Minglong; Yin, Xuntao; Chen, Lin; Zhang, Jiuquan; Wang, Jian

    2016-01-01

    Amyotrophic lateral sclerosis (ALS) is a rare degenerative disorder characterized by loss of upper and lower motor neurons. Neuroimaging has provided noticeable evidence that ALS is a complex disease, and shown that anatomical and functional lesions extend beyond precentral cortices and corticospinal tracts, to include the corpus callosum; frontal, sensory, and premotor cortices; thalamus; and midbrain. The aim of this study is to investigate graph theory-based functional network abnormalities at voxel-wise level in ALS patients on a whole brain scale. Forty-three ALS patients and 44 age- and sex-matched healthy volunteers were enrolled. The voxel-wise network degree centrality (DC), a commonly employed graph-based measure of network organization, was used to characterize the alteration of whole brain functional network. Compared with the controls, the ALS patients showed significant increase of DC in the left cerebellum posterior lobes, bilateral cerebellum crus, bilateral occipital poles, right orbital frontal lobe, and bilateral prefrontal lobes; significant decrease of DC in the bilateral primary motor cortex, bilateral sensory motor region, right prefrontal lobe, left bilateral precuneus, bilateral lateral temporal lobes, left cingulate cortex, and bilateral visual processing cortex. The DC's z-scores of right inferior occipital gyrus were significant negative correlated with the ALSFRS-r scores. Our findings confirm that the regions with abnormal network DC in ALS patients were located in multiple brain regions including primary motor, somatosensory and extra-motor areas, supporting the concept that ALS is a multisystem disorder. Specifically, our study found that DC in the visual areas was altered and ALS patients with higher DC in right inferior occipital gyrus have more severity of disease. The result demonstrated that the altered DC value in this region can probably be used to assess severity of ALS.

  15. Brain-Wise Leadership

    Science.gov (United States)

    Murphy, Carole; Ozturgut, Osman; French, Joan

    2013-01-01

    The purpose of this article is to help leaders do their jobs more effectively by examining the components of brain-wise leadership. The article is divided into five parts: Part I is a general overview, defining brain-wise leadership, its traits, attributes and some of the styles of effective leadership. Part II begins with the strategies for…

  16. Is there a step-wise migration in Nigeria? A case study of the migrational histories of migrants in Lagos.

    Science.gov (United States)

    Afolayan, A A

    1985-09-01

    "The paper sets out to test whether or not the movement pattern of people in Nigeria is step-wise. It examines the spatial order in the country and the movement pattern of people. It then analyzes the survey data and tests for the validity of step-wise migration in the country. The findings show that step-wise migration cannot adequately describe all the patterns observed." The presence of large-scale circulatory migration between rural and urban areas is noted. Ways to decrease the pressure on Lagos by developing intermediate urban areas are considered. excerpt

  17. Step-Wise Migration : Evidence from Indonesia

    NARCIS (Netherlands)

    Pardede, Elda; McCann, Philip; Venhorst, Viktor

    2016-01-01

    The objective of this paper is to study multiple internal migration trajectories in Indonesia, with special attention to step-wise migration. Step-wise migration involves moves with smaller steps from village to nearby small town, to larger town, and then to big cities rather than a direct move from

  18. Modification of the School Cafeteria Environment Can Impact Childhood Nutrition: Results from the Wise Mind and LA Health Studies

    Science.gov (United States)

    Williamson, Donald A.; Han, Hongmei; Johnson, William D.; Martin, Corby K.; Newton, Robert L.

    2014-01-01

    Recent changes in nutrition standards for the National School Lunch and School Breakfast Programs assume that modification of the nutritional serving practices of school cafeterias will result in improved childhood nutrition in the school environment. The primary aim of this paper is to summarize the findings from two recent cluster randomized controlled trials (Wise Mind and LA Health) that tested the hypothesis that modification of school cafeteria environments, including changes in nutrition standards, would yield beneficial changes in childhood nutrition and healthy eating in the school lunch environment. A secondary aim was to investigate the association of participant characteristics and changes in nutrition and healthy eating. A third aim was to investigate the relationships between the food intake of children and: 1) foods selected by the children and 2) food that was uneaten during the lunch meal (plate waste). The studies used similar approaches for modifying the school cafeteria environment and both studies used the digital photography method to measure changes in food intake, food selection, and plate waste. Both studies reported significant improvements in childhood nutrition, and the LA Health study reported improved healthy eating, following introduction of the cafeteria modification program in comparison to baseline and/or control arms. These studies confirm the hypothesis that interventions that modify the school cafeteria environment can beneficially impact childhood nutrition. PMID:23154216

  19. Modification of the school cafeteria environment can impact childhood nutrition. Results from the Wise Mind and LA Health studies.

    Science.gov (United States)

    Williamson, Donald A; Han, Hongmei; Johnson, William D; Martin, Corby K; Newton, Robert L

    2013-02-01

    Recent changes in nutrition standards for the National School Lunch and School Breakfast Programs assume that modification of the nutritional serving practices of school cafeterias will result in improved childhood nutrition in the school environment. The primary aim of this paper is to summarize the findings from two recent cluster randomized controlled trials (Wise Mind and LA Health) that tested the hypothesis that modification of school cafeteria environments, including changes in nutrition standards, would yield beneficial changes in childhood nutrition and healthy eating in the school lunch environment. A secondary aim was to investigate the association of participant characteristics and changes in nutrition and healthy eating. A third aim was to investigate the relationships between the food intake of children and: (1) foods selected by the children and (2) food that was uneaten during the lunch meal (plate waste). The studies used similar approaches for modifying the school cafeteria environment and both studies used the digital photography method to measure changes in food intake, food selection, and plate waste. Both studies reported significant improvements in childhood nutrition, and the LA Health study reported improved healthy eating, following introduction of the cafeteria modification program in comparison to baseline and/or control arms. These studies confirm the hypothesis that interventions that modify the school cafeteria environment can beneficially impact childhood nutrition. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Evaluation of an optimized [18F]fluoro-deoxy-glucose positron emission tomography voxel-wise method to early support differential diagnosis in atypical Parkinsonian disorders.

    Science.gov (United States)

    Caminiti, S P; Alongi, P; Majno, L; Volontè, M A; Cerami, C; Gianolli, L; Comi, G; Perani, D

    2017-05-01

    Atypical Parkinsonian disorders (APD) frequently overlap in clinical presentations, making the differential diagnosis challenging in the early stages. The present study aimed to evaluate the accuracy of the [ 18 F]fluoro-deoxy-glucose positron emission tomography Statistical Parametric Mapping (SPM) optimized procedure in supporting the early and differential diagnosis of APD. Seventy patients with possible APD were retrospectively included from a large clinical cohort. The included patients underwent [ 18 F]fluoro-deoxy-glucose positron emission tomography within 3 months of the first clinical assessment and a diagnostic follow-up. An optimized SPM voxel-wise procedure was used to produce t-maps of brain hypometabolism in single subjects, which were classified by experts blinded to any clinical information. We compared the accuracy of both the first clinical diagnosis and the SPM t-map classifications with the diagnosis at follow-up as the reference standard. At first diagnosis, 60% of patients were classified as possible APD (progressive supranuclear palsy, corticobasal degeneration, dementia with Lewy bodies, multiple system atrophy) and about 40% as APD with uncertain diagnosis, providing 52% sensitivity, 97% specificity and 86% accuracy with respect to the reference standard. SPM t-map classification showed 98% sensitivity, 99% specificity and 99% accuracy, and a significant agreement with the diagnosis at follow-up (P map classification at entry predicted the second diagnosis at follow-up. This indicates its significantly superior role for an early identification of APD subtypes, particularly in cases of uncertain diagnosis. The use of a metabolic biomarker at entry in the instrumental work-up of APD may shorten the diagnostic time, producing benefits for treatment options and support to the patients. © 2017 EAN.

  1. Wise Women: A Narrative Study of Former Living-Learning Community Participants' Experiences as STEM Majors

    Science.gov (United States)

    Grays, Shaefny D.

    2013-01-01

    Over the past few decades, higher education has attempted to address the issue of underrepresentation of women in STEM undergraduate degree programs. Living-learning communities represent one strategy to help address low persistence for women in undergraduate STEM majors. The purpose of this study was to explore the experiences of undergraduate…

  2. Persuading giants to be wise: an exploratory study of advice sharing in online games

    OpenAIRE

    Ruskov, M.; Seager, W.; Sasse, M. A.

    2010-01-01

    This study investigates the effects of a browser game as a motivational factor for the sharing of short written reflections. We have analysed 400 anonymous written reflections and conducted 10 interviews in order to get a deeper insight of the game experience. This is an opportunistic investigation and the authors did not have control over the game environment. We have found that there is a predominantly positive attitude towards the approach taken by the game, and a significantly higher leve...

  3. Empirical evidence about inconsistency among studies in a pair-wise meta-analysis.

    Science.gov (United States)

    Rhodes, Kirsty M; Turner, Rebecca M; Higgins, Julian P T

    2016-12-01

    This paper investigates how inconsistency (as measured by the I(2) statistic) among studies in a meta-analysis may differ, according to the type of outcome data and effect measure. We used hierarchical models to analyse data from 3873 binary, 5132 continuous and 880 mixed outcome meta-analyses within the Cochrane Database of Systematic Reviews. Predictive distributions for inconsistency expected in future meta-analyses were obtained, which can inform priors for between-study variance. Inconsistency estimates were highest on average for binary outcome meta-analyses of risk differences and continuous outcome meta-analyses. For a planned binary outcome meta-analysis in a general research setting, the predictive distribution for inconsistency among log odds ratios had median 22% and 95% CI: 12% to 39%. For a continuous outcome meta-analysis, the predictive distribution for inconsistency among standardized mean differences had median 40% and 95% CI: 15% to 73%. Levels of inconsistency were similar for binary data measured by log odds ratios and log relative risks. Fitted distributions for inconsistency expected in continuous outcome meta-analyses using mean differences were almost identical to those using standardized mean differences. The empirical evidence on inconsistency gives guidance on which outcome measures are most likely to be consistent in particular circumstances and facilitates Bayesian meta-analysis with an informative prior for heterogeneity. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd. © 2015 The Authors. Research Synthesis Methods published by John Wiley & Sons, Ltd.

  4. Design, construction, and technical implementation of a web-based interdisciplinary symptom evaluation (WISE) - a heuristic proposal for orofacial pain and temporomandibular disorders.

    Science.gov (United States)

    Ettlin, Dominik A; Sommer, Isabelle; Brönnimann, Ben; Maffioletti, Sergio; Scheidt, Jörg; Hou, Mei-Yin; Lukic, Nenad; Steiger, Beat

    2016-12-01

    Medical symptoms independent of body location burden individuals to varying degrees and may require care by more than one expert. Various paper and computer-based tools exist that aim to comprehensively capture data for optimal clinical management and research. A web-based interdisciplinary symptom evaluation (WISE) was newly designed, constructed, and technically implemented. For worldwide applicability and to avoid copyright infringements, open source software tools and free validated questionnaires available in multiple languages were used. Highly secure data storage limits access strictly to those who use the tool for collecting, storing, and evaluating their data. Concept and implementation is illustrated by a WISE sample tailored for the requirements of a single center in Switzerland providing interdisciplinary care to orofacial pain and temporomandibular disorder patients. By combining a symptom- burden checklist with in-depth questionnaires serving as case-finding instruments, an algorithm was developed that assists in clarifying case complexity and need for targeted expert evaluation. This novel modular approach provides a personalized, response-tailored instrument for the time- and cost-effective collection of symptom-burden focused quantitative data. The tool includes body drawing options and instructional videos. It is applicable for biopsychosocial evaluation in a variety of clinical settings and offers direct feedback by a case report summary. In clinical practice, the new instrument assists in clarifying case complexity and referral need, based on symptom burden and response -tailored case finding. It provides single-case summary reports from a biopsychosocial perspective and includes graphical symptom maps. Secure, centrally stored data collection of anonymous data is possible. The tool enables personalized medicine, facilitates interprofessional education and collaboration, and allows for multicenter patient-reported outcomes research.

  5. Batch-wise adsorption, saxs and microscopic studies of zeolite pelletized with biopolymeric alginate

    Directory of Open Access Journals (Sweden)

    E. Chmielewská

    2011-03-01

    Full Text Available Removal of nitrates, sulfate and Zn(II ions from aqueous solutions through adsorption onto biopolymeric alginate/clinoptilolite-rich tuff pellets was studied by using an equilibrium batch technique. The idea of this approach of biosorbent fabrication is to promote the native zeolite adsorption performance and thus to prepare more efficient amphoteric tailor-made products for specific environmental targets. A flexible component, i.e., alginate biopolymer, and a rigid component (pulverized zeolite were crosslinked using Fe(III and Ca(II chlorides, additively. The extent of adsorption was found to be considerably higher than with the other mostly natural adsorbents examined towards similar pollutants. The equilibrium adsorption data for the above pollutants were satisfactorily fitted to Freundlich and Langmuir isotherms, respectively. According to the linscale SAXS pattern, there was a strong background visible, which may indicate the presence of a considerable amount of biopolymeric phase in the composite samples analysed. Scanning Tunneling, Electron and Atomic Force Microscopies helped visualize their surface texture and morphology.

  6. High Protein Intake Improves Insulin Sensitivity but Exacerbates Bone Resorption in Immobility (WISE Study)

    Science.gov (United States)

    Heer, Martina; Smith, Scott M.; Frings-Meuthen, Petra; Zwart, Sara R.; Baecker, Natalie

    2012-01-01

    Inactivity, like bed rest (BR), causes insulin resistance (IR) and bone loss even in healthy subjects. High protein intake seems to mitigate this IR but might exacerbate bone loss. We hypothesized that high protein intake (animal:vegetable protein ratio: 60:40), isocaloric, compared to the control group plus high potassium intake would prevent IR without affecting bone turnover. After a 20-day ambulatory adaptation to controlled confinement and diet, 16 women participated in a 60-day, 6 deg head-down-tilt BR and were assigned randomly to one of the two groups. Control subjects (CON, n=8) received 1g/kg body mass/d dietary protein. Nutrition subjects (NUT, n=8) received 1.45g/kg body mass/d dietary protein plus 7.2g branched chain amino acids per day during BR. All subjects received 1670 kcal/d. Bed rest decreased glucose disposal by 35% (pprotein intake prevented insulin resistance, but exacerbated bed rest induced increase in bone resorption markers C-telopeptide (> 30%) and Ntelopeptide (>20%) (both: pprotein intake. We conclude from these results that high protein intake might positively affect glucose tolerance, but might also foster bone loss. Further long-duration studies are mandatory before high protein intake for diabetic patients, who have an increased fracture risk, might be recommended.

  7. Equivalent model construction for a non-linear dynamic system based on an element-wise stiffness evaluation procedure and reduced analysis of the equivalent system

    Science.gov (United States)

    Kim, Euiyoung; Cho, Maenghyo

    2017-11-01

    In most non-linear analyses, the construction of a system matrix uses a large amount of computation time, comparable to the computation time required by the solving process. If the process for computing non-linear internal force matrices is substituted with an effective equivalent model that enables the bypass of numerical integrations and assembly processes used in matrix construction, efficiency can be greatly enhanced. A stiffness evaluation procedure (STEP) establishes non-linear internal force models using polynomial formulations of displacements. To efficiently identify an equivalent model, the method has evolved such that it is based on a reduced-order system. The reduction process, however, makes the equivalent model difficult to parameterize, which significantly affects the efficiency of the optimization process. In this paper, therefore, a new STEP, E-STEP, is proposed. Based on the element-wise nature of the finite element model, the stiffness evaluation is carried out element-by-element in the full domain. Since the unit of computation for the stiffness evaluation is restricted by element size, and since the computation is independent, the equivalent model can be constructed efficiently in parallel, even in the full domain. Due to the element-wise nature of the construction procedure, the equivalent E-STEP model is easily characterized by design parameters. Various reduced-order modeling techniques can be applied to the equivalent system in a manner similar to how they are applied in the original system. The reduced-order model based on E-STEP is successfully demonstrated for the dynamic analyses of non-linear structural finite element systems under varying design parameters.

  8. [Choosing Wisely in medical education].

    Science.gov (United States)

    Goldmann, Milena; Middeke, Angelina-Charline; Schuelper, Nikolai; Dehl, Terese; Raupach, Tobias

    2017-12-01

    Choosing Wisely recommendations address situations where physicians will have to make decisions about further diagnostic and therapeutic steps. Undergraduate medical education needs to equip students with the foundations on which clinical reasoning skills can be acquired and fostered throughout their clinical career. Teaching these skills usually involves patients (e.g., bedside teaching, electives, clinical attachments) but it can also be delivered in the format of formalised small-group, case-based learning. Case-based key feature tests have been developed to facilitate the assessment of learning outcomes related to clinical reasoning. Repeated testing with key feature cases yields better medium-term retention than repeatedly studying the same material (without questions). The project 'Choosing Wisely in medical education', which was funded by the German Association for Internal Medicine, involves the creation of key feature cases with reference to the German set of Choosing Wisely recommendations. This article presents the results of the first pilot study using these new cases. Copyright © 2017. Published by Elsevier GmbH.

  9. Constructing a WISE High Resolution Galaxy Atlas

    Science.gov (United States)

    Jarrett, T. H.; Masci, F.; Tsai, C. W.; Petty, S.; Cluver, M.; Assef, Roberto J.; Benford, D.; Blain, A.; Bridge, C.; Donoso, E.; hide

    2012-01-01

    After eight months of continuous observations, the Wide-field Infrared Survey Explorer (WISE) mapped the entire sky at 3.4 micron, 4.6 micron, 12 micron, and 22 micron. We have begun a dedicated WISE High Resolution Galaxy Atlas project to fully characterize large, nearby galaxies and produce a legacy image atlas and source catalog. Here we summarize the deconvolution techniques used to significantly improve the spatial resolution of WISE imaging, specifically designed to study the internal anatomy of nearby galaxies. As a case study, we present results for the galaxy NGC 1566, comparing the WISE enhanced-resolution image processing to that of Spitzer, Galaxy Evolution Explorer, and ground-based imaging. This is the first paper in a two-part series; results for a larger sample of nearby galaxies are presented in the second paper.

  10. Astro-WISE and Grid

    NARCIS (Netherlands)

    Begeman, Kor; Belikov, Andrey N.; Dijkstra, Fokke; Meyer-Zhao, Zheng; Valentijn, Edwin A.; Vriend, Willem-Jan

    The paper reviews the Astro-WISE infrastructure and demonstrates that the Astro-WISE Information System provides a Grid itself. We describe the integration of Astro-WISE with an external Grid infrastructure (BiGGrid). The integration is performed on all infrastructural layers (data storage, metadata

  11. Astro-WISE information system

    NARCIS (Netherlands)

    Valentijn, E. A.; Belikov, A. N.; Kleijn, G. A. Verdoes; Williams, O.R.; Radziwill, NM; Chiozzi, G

    2012-01-01

    Astro-WISE is the first information system in astronomy which covers all aspects of data processing, storage and visualization. We show the various concepts behind the Astro-WISE, their realization and use, migration of Astro-WISE to other astronomical and non-astronomical information systems.

  12. Understanding Young Exoplanet Analogs with WISE

    Science.gov (United States)

    Rice, Emily

    We propose to tackle outstanding questions about the fundamental properties of young brown dwarfs, which are atmospheric analogs to massive gas giant exoplanets, using public archive data from the Wide-field Infrared Survey Explorer (WISE) combined with our extensive dataset of optical and near-infrared observations, including spectra, proper motions, and parallaxes. Using WISE data we will construct color-color diagrams, color- magnitude diagrams, and spectral energy distributions for our sample of candidate young brown dwarfs. We will fully characterize the spectral properties of the candidates and evaluate their membership in nearby young moving groups in order to obtain independent age estimates. The practical outcomes of this project will allow the research community to use observed colors and spectra to reliably constrain the properties - including effective temperature, gravity, and dust/cloud properties - of both brown dwarfs and gas giant exoplanets. We will also search for new young brown dwarfs in the WISE archive using colors and proper motions. The expanded sample of young brown dwarfs will be used to create a self-contained feedback loop to identify and address the shortcomings of cool atmosphere models and low-mass evolutionary tracks, both of which are already being used to infer the properties of massive exoplanets. Disentangling the effects of physical parameters on the observed properties of young brown dwarfs is directly relevant to studies of exoplanets. Direct observations of exoplanets are currently very limited, and young brown dwarfs are the laboratories in which we can solve existing problems before the onslaught of new observations from instruments capable of directly imaging exoplanets, including the Gemini Planet Imager, Project 1640 at the Palomar Observatory, SPHERE on the VLT, and the James Webb Space Telescope. This project addresses the goal of the NASA Science Mission Directorate to discover how the universe works; in particular

  13. The wise leader.

    Science.gov (United States)

    Nonaka, Ikujiro; Takeuchi, Hirotaka

    2011-05-01

    In an era of increasing discontinuity, wise leadership has nearly vanished. Many leaders find it difficult to reinvent their corporations rapidly enough to cope with new technologies, demographic shifts, and consumption trends. They can't develop truly global organizations that operate effortlessly across borders. And they find it tough to ensure that their people adhere to values and ethics. The authors assert that leaders must acquire practical wisdom, or what Aristotle called phronesis: experiential knowledge that enables people to make ethically sound judgments. Wise leaders demonstrate six abilities: (i) They make decisions on the basis of what is good for the organization and for society. (2) They quickly grasp the essence of a situation and fathom the nature and meaning of people, things, and events. (3) They provide contexts in which executives and employees can interact to create new meaning. (4) They employ metaphors and stories to convert their experience into tacit knowledge that others can use. (5) They exert political power to bring people together and spur them to act. (6) They use apprenticeship and mentoring to cultivate practical wisdom in orders.

  14. Number and function of bone-marrow derived angiogenic cells and coronary flow reserve in women without obstructive coronary artery disease: a substudy of the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE.

    Directory of Open Access Journals (Sweden)

    Rajesh Mohandas

    Full Text Available BACKGROUND: In women with ischemia and no obstructive coronary artery disease, the Women's Ischemic Syndrome Evaluation (WISE observed that microvascular coronary dysfunction (MCD is the best independent predictor of adverse cardiovascular events. Since coronary microvascular tone is regulated in part by endothelium, we hypothesized that circulating endothelial cells (CEC, which reflect endothelial injury, and the number and function of bone-marrow derived angiogenic cells (BMDAC, which could help repair damaged endothelium, may serve as biomarkers for decreased coronary flow reserve (CFR and MCD. METHODS: We studied 32 women from the WISE cohort. CFR measurements in response to intracoronary adenosine were taken as an index of MCD. We enumerated BMDAC colonies and CEC in peripheral blood samples. BMDAC function was assessed by assay of migration of CD34+ cells toward SDF-1 and measurement of bioavailable nitric oxide (NO. These findings were compared with a healthy reference group and also entered into a multivariable model with CFR as the dependent variable. RESULTS: Compared with a healthy reference group, women with MCD had lower numbers of BMDAC colonies [16 (0, 81 vs. 24 (14, 88; P = 0.01] and NO [936 (156, 1875 vs. 1168 (668, 1823; P = 0.02]. Multivariable regression analysis showed strong correlation of CFR to the combination of BMDAC colony count and CD34+ cell function (migration and NO (R(2 = 0.45; P<0.05. CONCLUSIONS: The BMDAC function and numbers of BMDAC colonies are decreased in symptomatic women with MCD and are independently associated with CFR. These circulating cells may provide mechanistic insights into MCD in women with ischemia.

  15. Impact of HealthWise South Africa on polydrug use and high-risk sexual behavior.

    Science.gov (United States)

    Tibbits, Melissa K; Smith, Edward A; Caldwell, Linda L; Flisher, Alan J

    2011-08-01

    This study was designed to evaluate the efficacy of the HealthWise South Africa HIV and substance abuse prevention program at impacting adolescents' polydrug use and sexual risk behaviors. HealthWise is a school-based intervention designed to promote social-emotional skills, increase knowledge and refusal skills relevant to substance use and sexual behaviors, and encourage healthy free time activities. Four intervention schools in one township near Cape Town, South Africa were matched to five comparison schools (N = 4040). The sample included equal numbers of male and female participants (Mean age = 14.0). Multiple regression was used to assess the impact of HealthWise on the outcomes of interest. Findings suggest that among virgins at baseline (beginning of eighth grade) who had sex by Wave 5 (beginning of 10th grade), HealthWise youth were less likely than comparison youth to engage in two or more risk behaviors at last sex. Additionally, HealthWise was effective at slowing the onset of frequent polydrug use among non-users at baseline and slowing the increase in this outcome among all participants. Program effects were not found for lifetime sexual activity, condomless sex refusal and past-month polydrug use. These findings suggest that HealthWise is a promising approach to HIV and substance abuse prevention.

  16. User Documentation; WISE-ONE.

    Science.gov (United States)

    Olson, Tom; And Others

    WISE-ONE, an information retrieval system, was designed to facilitate searches of the documents cataloged by the ERIC centers and distributed as ERIC RESUMAST master files. WISE-ONE is written to search for documents cataloged under any of the three indices (descriptors, identifiers, and author name), called search keys, and will yield the ERIC…

  17. WISE design for knowledge integration

    Science.gov (United States)

    Linn, Marcia C.; Clark, Douglas; Slotta, James D.

    2003-07-01

    Scaling research-based curriculum to the multitude of science teaching standards and contexts has proven difficult in the past. To respond to the challenge, the Web-based Inquiry Science Environment (WISE) offers designers a technology-enhanced, research-based, flexibly adaptive learning environment. The learning environment can incorporate new features such as modeling tools or hand-held devices. Using WISE, design teams can create projects that bend but do not break when customized to support new school contexts and state standards. WISE curriculum projects are created by diverse design teams that include classroom teachers, technologists, discipline experts, pedagogy researchers, and curriculum designers. WISE inquiry projects incorporate Internet materials and build on the commitments and talents of teachers as well as the constraints and opportunities of their classroom contexts rather than imposing new practices without concern for past successes. These design teams create projects that incorporate diverse features of the WISE learning environment to form specific patterns that are then combined into whole projects. We refer to the whole projects as implementing curriculum design patterns for student activities. The projects are tested to determine how the curriculum design patterns promote knowledge integration, then reviewed by WISE researchers and revised accordingly (see M. C. Linn, P. Bell, & E. A. Davis, in press, Internet Environments for Science Education). Hillsdale, NJ: Erlbaum.). The most successful projects become part of the WISE library. This paper describes WISE design team practices, features of the WISE learning environment, and patterns of feature use in current library projects. The success of WISE in classrooms illustrates how flexibly adaptive projects can meet the needs of diverse teachers. Variation amongst library projects shows that designers can support inquiry with a wide variety of activities. Taken together, the library of

  18. Using Data Wisely at the System Level

    Science.gov (United States)

    Lockwood, Meghan; Dillman, Mary; Boudett, Kathryn Parker

    2017-01-01

    District administrators who want to build capacity for data use in schools may be well-served by starting in the central office. This case study of the Boston Public Schools shows how central office administrators can leverage their own data inquiry cycles to improve the ways they support schools in using data. Using the Data Wise Improvement…

  19. Molecular evaluation of genetic diversity and association studies in ...

    Indian Academy of Sciences (India)

    Molecular evaluation of genetic diversity and association studies in rice. (Oryza sativa L.) C. Vanniarajan, K. K. Vinod and Andy Pereira. J. Genet. 91, 9–19. Table 1. Chromosome-wise distribution of SSR alleles and their number (k), polymorphic information content (PIC) and allele discrimination index (Dm). Chromosome.

  20. Wise regulates bone deposition through genetic interactions with Lrp5.

    Directory of Open Access Journals (Sweden)

    Debra L Ellies

    Full Text Available In this study using genetic approaches in mouse we demonstrate that the secreted protein Wise plays essential roles in regulating early bone formation through its ability to modulate Wnt signaling via interactions with the Lrp5 co-receptor. In Wise-/- mutant mice we find an increase in the rate of osteoblast proliferation and a transient increase in bone mineral density. This change in proliferation is dependent upon Lrp5, as Wise;Lrp5 double mutants have normal bone mass. This suggests that Wise serves as a negative modulator of Wnt signaling in active osteoblasts. Wise and the closely related protein Sclerostin (Sost are expressed in osteoblast cells during temporally distinct early and late phases in a manner consistent with the temporal onset of their respective increased bone density phenotypes. These data suggest that Wise and Sost may have common roles in regulating bone development through their ability to control the balance of Wnt signaling. We find that Wise is also required to potentiate proliferation in chondrocytes, serving as a potential positive modulator of Wnt activity. Our analyses demonstrate that Wise plays a key role in processes that control the number of osteoblasts and chondrocytes during bone homeostasis and provide important insight into mechanisms regulating the Wnt pathway during skeletal development.

  1. A pilot cluster randomised controlled trial of a support and training intervention to improve the mental health of secondary school teachers and students - the WISE (Wellbeing in Secondary Education) study.

    Science.gov (United States)

    Kidger, Judi; Stone, Tracey; Tilling, Kate; Brockman, Rowan; Campbell, Rona; Ford, Tamsin; Hollingworth, William; King, Michael; Araya, Ricardo; Gunnell, David

    2016-10-06

    Secondary school teachers are at heightened risk of psychological distress, which can lead to poor work performance, poor quality teacher-student relationships and mental illness. A pilot cluster randomised controlled trial (RCT) - the WISE study - evaluated the feasibility of a full-scale RCT of an intervention to support school staff's own mental health, and train them in supporting student mental health. Six schools were randomised to an intervention or control group. In the intervention schools i) 8-9 staff received Mental Health First Aid (MHFA) training and became staff peer supporters, and ii) youth MHFA training was offered to the wider staff body. Control schools continued with usual practice. We used thematic qualitative data analysis and regression modelling to ascertain the feasibility, acceptability and potential usefulness of the intervention. Thirteen training observations, 14 staff focus groups and 6 staff interviews were completed, and 438 staff (43.5 %) and 1,862 (56.3 %) students (years 8 and 9) completed questionnaires at baseline and one year later. MHFA training was considered relevant for schools, and trainees gained in knowledge, confidence in helping others, and awareness regarding their own mental health. Suggestions for reducing the length of the training and focusing on helping strategies were made. A peer support service was established in all intervention schools and was perceived to be helpful in supporting individuals in difficulty - for example through listening, and signposting to other services - and raising the profile of mental health at a whole school level. Barriers to use included lack of knowledge about the service, concerns about confidentiality and a preference for accessing support from pre-existing networks. The WISE intervention is feasible and acceptable to schools. Results support the development of a full-scale cluster RCT, if steps are taken to improve response rates and implement the suggested improvements to the

  2. Med Wise: A theory-based program to improve older adults' communication with pharmacists about their medicines.

    Science.gov (United States)

    Martin, B A; Chewning, B A; Margolis, A R; Wilson, D A; Renken, J

    2016-01-01

    The health and economic toll of medication errors by older adults is well documented. Poor communication and medication coordination problems increase the likelihood of adverse drug events (ADEs). Older adults have difficulty communicating with health care professionals, including pharmacists. As such, the theory-based Med Wise program was designed. Building on the Self-efficacy Framework and the Chronic Care Model, this program was tested with community-dwelling older adults. This study and its resultant paper: (1) describe the theory-based design of the Med Wise program; (2) describe the collaboration of multiple community partners to develop a sustainable model for implementing Med Wise; and (3) present findings from the Med Wise course evaluation. Med Wise was designed to be a sustainable, skill-based educational and behavior change program consisting of two, 2-h interactive classes to enhance participants' medication communication skills and self-efficacy. To explore the potential to disseminate Med Wise throughout the state, a partnership was formed between the pharmacy team and the statewide Aging & Disability Resource Centers (ADRCs), as well as the Community-Academic Aging Research Network (CAARN). Over 30 lay volunteer leaders in 8 Wisconsin (U.S. State) counties were trained, and they delivered Med Wise through ADRC community centers. The CAARN staff evaluated the fidelity of the course delivery by leaders. To evaluate Med Wise, a quasi-experimental design using pre/post surveys assessed knowledge, worry and self-efficacy. A telephone follow-up three months later assessed self-efficacy and translation of medication management skills and behaviors. Med Wise programs were presented to 198 community-dwelling older adults while maintaining program fidelity. This evaluation found significant increases in older adults' knowledge about pharmacists' roles and responsibilities, likelihood of talking with a pharmacist about medication concerns, and self

  3. The Effects of One-Stage Full-Mouth Disinfection and Qua-drant-Wise Scaling and Root Planing on Serum Levels of IL-17 and IL-1β and Clinical Parameters (A randomized Controlled Trial Study

    Directory of Open Access Journals (Sweden)

    Adileh Shirmohammadi

    2013-01-01

    Full Text Available Objective: One-stage full-mouth disinfection technique (FMD has been introduced to avoid cross-contamination between the treated and untreated regions between treatment sessions. Considering the role of inflammatory mediators in periodontitis, the aim of the present study was to compare the effects of FMD with the quadrant-wise scaling and root planing (Q-SRP on serum levels of IL-17 and IL-1β in patients with moderate-to-severe chronic periodontitis.Materials and Methods: Twenty patients with chronic periodontitis were selected randomly and based on inclusion criteria in each group. In order to evaluate the periodontal status, the clinical parameters of bleeding on probing (BOP, clinical attachment level (CAL, probing depth (PD and modified gingival index (MGI were measured and recorded before treatment and at 2- and 4-month intervals after treatment. Immunologic parameters of the study such as IL-17 and IL-1β serum levels were determined by special laboratory kits at the same intervals. Data were analyzed by SPSS 15 statistical software. Statistical significance was defined at p0.05. In the evaluation of periodontal parameters, all parameters exhibited clinical improvements in both groups, with no statistically significant differences between the two study groups (p>0.05.Conclusion: Based on the results of the present study it was concluded that both FMD and Q-SRP techniques result in improvements in periodontal indexes and decreases in the serum levels of IL-17 and IL-1β inflammatory mediators.

  4. Wise Creativity and Creative Wisdom

    DEFF Research Database (Denmark)

    Knoop, Hans Henrik

    2008-01-01

    This important new volume from Anna Craft, Howard Gardner and Guy Claxton focuses on the need to educate students for "wise creativity" - the ability to expand their perspectives and exercise their talents responsibly within their school communicaty and in the real world.......This important new volume from Anna Craft, Howard Gardner and Guy Claxton focuses on the need to educate students for "wise creativity" - the ability to expand their perspectives and exercise their talents responsibly within their school communicaty and in the real world....

  5. Local zone wise elastic and plastic properties of electron beam welded Ti-6Al-4V alloy using digital image correlation technique: A comparative study between uniform stress and virtual fields method

    Science.gov (United States)

    Saranath, K. M.; Ramji, M.

    2015-05-01

    Joining of materials using welding results in the formation of material zones with varying microstructure across the weld. Extraction of the mechanical properties of those individual heterogeneous zones are important in designing components and structures comprised of welds. In this study, the zone wise local extraction of the elastic and plastic properties of an electron beam welded Ti-6Al-4V titanium alloy has been carried out using both the uniform stress method (USM) and the virtual fields method (VFM) involving digital image correlation (DIC) technique. The surface strain field obtained using DIC technique from a transverse weld specimen tensile testing is used for extracting the zone wise strain evolution. Initially, using uniform stress assumption, zone wise full range stress-strain curves are extracted. In USM methodology, the elastic and plastic material models are fitted to the zone wise stress-strain curves and required parameters are extracted from it. But inherent disadvantage is lot of images need to be processed for the parameter extraction. Recently, VFM is gaining lot of popularity in characterization domain as it is robust, accurate and faster. VFM is based on the principle of virtual work where, the weak form of local equilibrium equations and kinematically admissible virtual displacement fields are utilized for parameter extraction. Hollomon's power law is used here as the hardening rule. Young's modulus, Poisson's ratio, yield stress, strength coefficient and strain hardening exponent are the parameters extracted zone wise using both USM and VFM. A Vicker's microhardness measurement is also conducted across the weld zone towards mapping the strength behavior. Fusion zone has reported higher yield strength, strength coefficient and Poisson's ratio. Young's modulus value is found decreasing from base metal towards the fusion zone. The trend observed in parameter variation across the weld zone obtained by both USM and VFM compares very well. Due

  6. Equivalent reductions in body weight during the Beef WISE Study: beef's role in weight improvement, satisfaction and energy.

    Science.gov (United States)

    Sayer, R D; Speaker, K J; Pan, Z; Peters, J C; Wyatt, H R; Hill, J O

    2017-09-01

    The objective of this randomized equivalence trial was to determine the impact of consuming lean beef as part of a high protein (HP) weight-reducing diet on changes in body weight, body composition and cardiometabolic health. A total of 120 adults (99 female) with overweight or obesity (BMI: 35.7 ± 7.0 kg m-2) were randomly assigned to consume either a HP diet with ≥4 weekly servings of lean beef (B; n = 60) or a HP diet restricted in all red meats (NB; n = 60) during a 16-week weight loss intervention. Body weight was reduced by 7.8 ± 5.9% in B and 7.7 ± 5.5% in NB (p equivalent between B and NB (mean difference: 0.06%, 90% confidence interval: (-1.7, 1.8)). Fat mass was reduced in both groups (p mass was not reduced in either group. Improvements in markers of cardiometabolic health (total cholesterol, low-density lipoprotein cholesterol, triglycerides and blood pressure) were not different between B and NB. Results of this study demonstrate that HP diets - either rich or restricted in red meat intakes - are effective for decreasing body weight and improving body composition and cardiometabolic health.

  7. FLOODPLAIN, WISE COUNTY, TEXAS

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classificatinos used are the...

  8. StreetWise: developing a serious game to support forensic mental health service users' preparation for discharge: a feasibility study.

    Science.gov (United States)

    Reynolds, L M; Davies, J P; Mann, B; Tulloch, S; Nidsjo, A; Hodge, P; Maiden, N; Simpson, A

    2017-05-01

    WHAT IS KNOWN ON THE SUBJECT?: Serious gaming can support learning and development. The use of serious games for skills development and the rehearsal of the management of events that cannot be replicated in real life is well established. Few serious games have been used in mental health services, and none in forensic mental health care. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: How a serious game may be coproduced by forensic mental health service users and game developers The acceptability of the therapeutic use of serious gaming by forensic mental health service users and providers. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Computer games may be used by practitioners in their therapeutic work with forensic mental health service users. Mental health nurses to use serious games to creatively and safely bridge the gap for service users between receiving care in controlled environments and living more independent in the community. Introduction Assessment of users' skills and confidence to safely respond to risky community-based situations underpins discharge planning. Serious games have been used for skills development, and this study trialled their use in forensic mental health services. Aim The aim was to develop and test the acceptability and usability of an innovative serious game to support forensic mental health service users' preparation for discharge. Method A prototype serious game was developed by service users and researchers. Acceptability and usability testing was undertaken and service providers interviewed about the acceptability of serious gaming for forensic mental health services. Result A prototype game was produced and successfully trialled by service users. However, both service users and providers identified that work needed to be done to develop and test a game with greater complexity. Discussion The acceptability and usability of using serious games to support service users to develop skills needed for successful discharge was demonstrated

  9. The data zoo in Astro-WISE

    NARCIS (Netherlands)

    Kleijn, Gijs A. Verdoes; Belikov, Andrey N.; McFarland, John P.

    In this paper we describe the way the Astro-WISE information system (or simply Astro-WISE) supports the data from a wide range of instruments and combines multiple surveys and their catalogues. Astro-WISE allows ingesting of data from any optical instrument, survey or catalogue, processing of this

  10. Making Kids Space Wise

    Science.gov (United States)

    Berry, Steven R.

    2002-01-01

    Organizations that build the world's space training systems have access to a wealth of engineering and operations knowledge. That knowledge is organized and packaged into some of the world's top-notch technical curricula and courses - courses that reach a training audience of astronauts and cosmonauts, mission controllers, and engineering support teams. What if that same knowledge and course media could be redesigned, repackaged, and taught to our world's youth? The space engineering and technology outreach opportunities would be tremendous. This paper presents an example of a hands-on educational outreach program that was designed around this concept, and has been used in U.S. high schools to teach Geography, Physics and Earth Science students how space vehicle engineering and remote sensing operations relate to their daily studies. Authors' Biographical Sketch Steven Berry is a Senior Principal Product Engineer with The Boeing Company. Mr. Berry graduated from the University of Illinois with a B.S. in Aerospace Engineering, 1985. He is a 1992 alumnus of the International Space University. He received an M.A. in Multi-Cultural Studies from the University of Houston, Clear Lake, 1993. Among his recent business accomplishments, Mr. Berry led a multi-national, global engineering team in prototyping a distributed simulator to be used for ground astronaut training delivery on the international space station program. He has been involved in educational outreach programs in local schools, and has participated in national workshops on educational outreach and e-learning. Mr. Berry leads an organizational effectiveness project at The Boeing Company that facilitates work teams, and deploys workforce teambuilding and leadership programs. He also oversees workforce training programs for software engineering and business initiatives at The Boeing Company.

  11. Comparison of step-wise and ramp-wise incremental rowing exercise tests and 2000-m rowing ergometer performance.

    Science.gov (United States)

    Ingham, Stephen A; Pringle, Jamie S; Hardman, Sarah L; Fudge, Barry W; Richmond, Victoria L

    2013-03-01

    This study examined parameters derived from both an incremental step-wise and a ramp-wise graded rowing exercise test in relation to rowing performance. Discontinuous step-wise incremental rowing to exhaustion established lactate threshold (LT), maximum oxygen consumption (VO(2maxSTEP)), and power associated with VO(2max) (W VO(2max)). A further continuous ramp-wise test was undertaken to derive ventilatory threshold (VT), maximum oxygen consumption (VO(2maxRAMP)), and maximum minute power (MMW). Results were compared with maximal 2000-m ergometer time-trial power. The strongest correlation with 2000-m power was observed for MMW (r = .98, P rowing performance and thus may have potential as an influential monitoring tool for rowing athletes.

  12. A pilot cluster randomised controlled trial of a support and training intervention to improve the mental health of secondary school teachers and students – the WISE (Wellbeing in Secondary Education study

    Directory of Open Access Journals (Sweden)

    Judi Kidger

    2016-10-01

    Full Text Available Abstract Background Secondary school teachers are at heightened risk of psychological distress, which can lead to poor work performance, poor quality teacher-student relationships and mental illness. A pilot cluster randomised controlled trial (RCT – the WISE studyevaluated the feasibility of a full-scale RCT of an intervention to support school staff’s own mental health, and train them in supporting student mental health. Methods Six schools were randomised to an intervention or control group. In the intervention schools i 8–9 staff received Mental Health First Aid (MHFA training and became staff peer supporters, and ii youth MHFA training was offered to the wider staff body. Control schools continued with usual practice. We used thematic qualitative data analysis and regression modelling to ascertain the feasibility, acceptability and potential usefulness of the intervention. Results Thirteen training observations, 14 staff focus groups and 6 staff interviews were completed, and 438 staff (43.5 % and 1,862 (56.3 % students (years 8 and 9 completed questionnaires at baseline and one year later. MHFA training was considered relevant for schools, and trainees gained in knowledge, confidence in helping others, and awareness regarding their own mental health. Suggestions for reducing the length of the training and focusing on helping strategies were made. A peer support service was established in all intervention schools and was perceived to be helpful in supporting individuals in difficulty – for example through listening, and signposting to other services - and raising the profile of mental health at a whole school level. Barriers to use included lack of knowledge about the service, concerns about confidentiality and a preference for accessing support from pre-existing networks. Conclusions The WISE intervention is feasible and acceptable to schools. Results support the development of a full-scale cluster RCT, if steps are taken to

  13. A step-wise approach to find a valid and feasible method to detect non-adherence to tuberculosis drugs.

    NARCIS (Netherlands)

    Ruslami, R.; Crevel, R. van; Berge, E van de; Alisjahbana, B.; Aarnoutse, R.E.

    2008-01-01

    A step-wise approach to identify valid and feasible methods to detect non-adherence to tuberculosis drugs was evaluated in a prospective study among pulmonary tuberculosis patients in an outpatient clinic in Indonesia. First, adherence was measured by self-reporting with the standardized Morisky

  14. WISE: From the Dimmest Stars to the most Luminous Galaxies!

    Science.gov (United States)

    Craig, N.; Mendez, B. J.; Wright, E. L.

    2004-12-01

    The Wide-field Infrared Survey Explorer (WISE) Mission, led by UCLA PI Dr. Edward L. Wright is a newly selected MIDEX Mission, scheduled to launch in Summer 2008. WISE will conduct a survey of the entire sky in the infrared (3.5 - 23 microns) with far greater sensitivity than any previous program or mission. WISE will catalogue more than 100,000 asteroids, discover the coolest, dimmest, and nearest stars to the Sun, and determine which are the most luminous galaxies in the Universe. The WISE survey will consist of over a million images, from which hundreds of millions of astronomical objects will be catalogued, providing a vast storehouse of knowledge about the Solar System, the Milky Way, and the Universe. We will discuss our plans for an Education and Public Outreach (E/PO) program for WISE, including how our program will leverage resources from other IR mission E/PO programs such as Spitzer and SOFIA. We will also discuss our plans to partner with the amateur astronomer community to reach out to the K-12 education community, including underserved communities. The University of California, Berkeley's SEGway group from the Space Sciences Laboratory will lead the E/PO efforts of the WISE Mission with formal and informal education partners such as NOAO, Hands-On-Universe, the American Museum of Natural History, Space Science Institute, Space Dynamics Laboratory, the Astronomical Society of the Pacific, and Cornerstone Evaluations. The outreach program of WISE will captivate a wide range of audiences in the formal and informal science education communities with beautiful imagery and engaging science.

  15. Exercise treadmill testing using a modified exercise protocol in women with suspected myocardial ischemia: findings from the National Heart, Lung and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE).

    Science.gov (United States)

    Lewis, Jannet F; McGorray, Susan; Lin, Lang; Pepine, Carl J; Chaitman, Bernard; Doyle, Mark; Edmundowicz, Daniel; Sharaf, Barry L; Merz, C Noel Bairey

    2005-03-01

    Exercise testing, a major diagnostic modality in individuals with suspected coronary artery disease (CAD), has in general demonstrated less overall diagnostic accuracy in women compared to men. As part of the WISE, a modified protocol was examined with the intention of improving reliability of exercise testing. Criteria for entry in the WISE study include clinically indicated coronary angiography. Exercise testing was performed using a protocol modified to be more appropriate for women. The study population consisted of 96 women, mean age of 55.8 y (range 34-77), who completed exercise treadmill test (ETT). Most (78%) were postmenopausal; 96% had >or =2 risk factors for CAD. By core laboratory angiography, 29/96 women had stenosis > or =50% in at least one coronary artery. Of these 29 women, 9 had abnormal ETT, yielding overall sensitivity of 31%. The remaining 20 women had normal (12/29, 41%) or nondiagnostic (8/29, 28%) studies. Among the 67 women with minimal or no coronary stenosis, 35 had no ischemic ST-segment changes during ETT, yielding overall specificity of 52%. Analysis with exclusion of women with nondiagnostic studies yielded sensitivity and specificity of 43% and 66%, respectively. The presence of coronary artery stenosis and inability to perform ETT, but not results of testing, predicted the outcomes of myocardial infarction, heart failure, and death. Exercise treadmill test appears to be of limited diagnostic value in women with suspected myocardial ischemia referred for coronary angiography. Sensitivity and specificity remain poor even with modified exercise protocol and core laboratory angiographic analysis. These findings merit consideration in view of current guidelines that recommend exercise testing in women with suspected CAD.

  16. Diffusion tensor imaging of normal white matter maturation from late childhood to young adulthood: voxel-wise evaluation of mean diffusivity, fractional anisotropy, radial and axial diffusivities, and correlation with reading development.

    Science.gov (United States)

    Qiu, Deqiang; Tan, Li-Hai; Zhou, Ke; Khong, Pek-Lan

    2008-06-01

    Using diffusion tensor MR imaging (DTI) and advanced voxel-wise analysis tools, we study diffusivity and anisotropy changes of white matter from late childhood to young adulthood, and correlate quantitative diffusion indices with Chinese and English reading performance scores. Seventy-five normal healthy school going ethnic Chinese students and young adults of three age groups were recruited (group 1, n=24, mean+/-SD=7.4+/-0.3 years; group 2, n=27, mean+/-SD=10.3+/-0.5 years; group 3, n=24, mean+/-SD=22.8+/-2.3 years). DTI was performed with 3 mm isotropic resolution to cover the entire brain. Voxel-wise analysis was performed using Tract-Based Spatial Statistics (TBSS) to localize regions of white matter showing significant changes of fractional anisotropy (FA), mean diffusivity (MD), and axial and radial diffusivities between groups. We found increased FA and decreased MD with increasing age in regions of cerebellar white matter, right temporal white matter, and a large portion of the superior frontal and parietal white matter driven by both the reduction of radial diffusivity and axial diffusivity with the former to a greater extent. Changes were continual from late childhood to young adulthood. Findings were confirmed by region-of-interest analysis in specific white matter tracts. After controlling for the effect of age, significant correlation was found between diffusion indices of the anterior limb of the left internal capsule and Chinese reading score (p=0.05), and of the corona radiata and English reading score (p=0.026 and p=0.029 for left and right, respectively). These DTI indices likely reflect the multiple biological processes that occur during brain development which provide the neural substrate for ongoing functional connectivity including for reading development.

  17. Wireless Positioning Based on a Segment-Wise Linear Approach for Modeling the Target Trajectory

    DEFF Research Database (Denmark)

    Figueiras, Joao; Pedersen, Troels; Schwefel, Hans-Peter

    2008-01-01

    measurements and the user mobility patterns. One class of typical human being movement patterns is the segment-wise linear approach, which is studied in this paper. Current tracking solutions, such as the Constant Velocity model, hardly handle such segment-wise linear patterns. In this paper we propose...... a segment-wise linear model, called the Drifting Points model. The model results in an increased performance when compared with traditional solutions....

  18. Water-wise Landscaping: Practical Turfgrass Areas

    OpenAIRE

    Kopp, Kelly; Johnson, Paul

    2011-01-01

    Of the seven guiding principles of water-wise landscaping (a.k.a. Xeriscaping™), the most controversial involves the use of turfgrass in the landscape. At times it has seemed that water-wise landscaping might not allow for the use of turfgrasses at all.

  19. The Astro-WISE datacentric information system

    NARCIS (Netherlands)

    Begeman, K.; Belikov, A. N.; Boxhoorn, D. R.; Valentijn, E. A.

    In this paper we present the various concepts behind the Astro-WISE Information System. The concepts form a blueprint for general scientific information systems (WISE) which can satisfy a wide and challenging range of requirements for the data dissemination, storage and processing for various fields

  20. Parenting Interventions Implementation Science: How Delivery Format Impacts the Parenting Wisely Program

    Science.gov (United States)

    Cotter, Katie L.; Bacallao, Martica; Smokowski, Paul R.; Robertson, Caroline I. B.

    2013-01-01

    Objectives: This study examines the implementation and effectiveness of Parenting Wisely, an Internet-based parenting skills intervention. The study assesses whether parents benefit from Parenting Wisely participation and whether the delivery format influences program effectiveness. Method: This study uses a quasi-experimental design.…

  1. Polarization-sensitive digital dermoscopy for image processing-assisted evaluation of atypical nevi: towards step-wise detection of melanoma

    Science.gov (United States)

    Yu, Lauren S.; Joseph, Anika O. N. R.; Lindsley, Erik H.; Farkas, Daniel L.

    2011-02-01

    We have taken a three-pronged approach to improving the current standard of melanoma detection: (a) we are developing a new hyperspectral imaging-based medical device aimed at noninvasively detecting melanoma (b) we used a commercially available hand-held microscope with polarization control as a dermoscope, to begin establishing an inexpensive, portable imaging capability that could help assess the risk of a particular lesion (pigmented nevus) harboring melanoma (c) we created an updated ABCD algorithm and user interface software that more accurately generates a single risk number (Total Dermoscopy Score), for allowing a trained clinician to better assess the need for seeing the patient whose internet-uploaded nevus images they are evaluating. The hyperspectral instrument (a) is discussed elsewhere, and we focus here on (b) and (c), in the hope of increasing melanoma awareness and early detection.

  2. A Point-Wise Quantification of Asymmetry Using Deformation Fields

    DEFF Research Database (Denmark)

    Ólafsdóttir, Hildur; Lanche, Stephanie; Darvann, Tron Andre

    2007-01-01

    of the resulting displacement vectors on the left and right side of the symmetry plane, gives a point-wise measure of asymmetry. The asymmetry measure was applied to the study of Crouzon syndrome using Micro CT scans of genetically modified mice. Crouzon syndrome is characterised by the premature fusion of cranial...

  3. WISE Observations of the Jupiter Trojan Clouds

    Science.gov (United States)

    Grav, Tommy; Mainzer, A. K.; Bauer, J. M.; Cutri, R.; Masiero, J.; McMillan, R. S.; Wright, E. L.; WISE Team

    2010-10-01

    The Wide-field Infrared Survey Explorer (WISE) started its all sky survey in early January 2010. It has a 40cm cryogenically-cooled telescope with four imagers capable of taking simultaneous exposures at 3.4, 4.6, 12 and 22 microns, with sensitivities several hundred times greater than previous surveys (Mainzer et al., 2006). As of early July, the spacecraft has surveyed 99% of the sky and has covered the entire leading and trailing Jupiter Trojan clouds in a unprecedented uniform fashion. Almost 1500 Trojans have been observed (more than one quarter of the known Trojan population), compiling the largest set of mid-IR observations for this population. Trojans are objects that are located in the L4 and L5 Lagrangian points of a planet's orbit and currently Jupiter is known to have almost four thousand such objects in its Trojan population. The size and relative distributions of the two clouds are still uncertain due to the limited area covered by current surveys, but current studies suggest that the number of Jupiter Trojans is about the same as that of the main belt asteroids of similar sizes (Dotto et al, 2008). The physical characteristics are even less understood, but show some similarities and differences with other populations of minor bodies in the outer Solar System. It is therefore important to compare the physical and dynamical properties of the Jupiter Trojans with those of the Centaurs, Trans-Neptunian Objects, and outer Dwarf Planets. We will present preliminary data results for the Trojan population observed with WISE, looking at the albedo and diameter populations of the population as a whole, as well as the similarities and differences between the two clouds.

  4. Fingerponds: seasonal integrated aquaculture in East African freshwater wetlands : exploring their potential for wise use strategies

    NARCIS (Netherlands)

    Kipkemboi, J.

    2006-01-01

    This study was stimulated by the need for an integrated approach in wetland wise use. Sustainable management is critical for long-term ecosystem health and people's livelihoods. The potential for smallholder integrated agriculture-aquaculture as one of the possible wetland wise use strategies was

  5. Global Soil Profile Data (ISRIC-WISE)

    Data.gov (United States)

    National Aeronautics and Space Administration — The ISRIC-WISE International soil profile data set consists of a homogenized, global set of 1,125 soil profiles for use by global modelers. These profiles provided...

  6. Infrared Astronomy Professional Development for K-12 Educators: WISE Telescope

    Science.gov (United States)

    Borders, Kareen; Mendez, B. M.

    2010-01-01

    K-12 educators need effective and relevant astronomy professional development. WISE Telescope (Wide-Field Infrared Survey Explorer) and Spitzer Space Telescope Education programs provided an immersive teacher professional development workshop at Arecibo Observatory in Puerto Rico during the summer of 2009. As many common misconceptions involve scale and distance, teachers worked with Moon/Earth scale, solar system scale, and distance of objects in the universe. Teachers built and used basic telescopes, learned about the history of telescopes, explored ground and satellite based telescopes, and explored and worked on models of WISE Telescope. An in-depth explanation of WISE and Spitzer telescopes gave participants background knowledge for infrared astronomy observations. We taught the electromagnetic spectrum through interactive stations. The stations included an overview via lecture and power point, the use of ultraviolet beads to determine ultraviolet exposure, the study of WISE lenticulars and diagramming of infrared data, listening to light by using speakers hooked up to photoreceptor cells, looking at visible light through diffraction glasses and diagramming the data, protocols for using astronomy based research in the classroom, and infrared thermometers to compare environmental conditions around the observatory. An overview of LIDAR physics was followed up by a simulated LIDAR mapping of the topography of Mars. We will outline specific steps for K-12 infrared astronomy professional development, provide data demonstrating the impact of the above professional development on educator understanding and classroom use, and detail future plans for additional K-12 professional development. Funding was provided by WISE Telescope, Spitzer Space Telescope, Starbucks, Arecibo Observatory, the American Institute of Aeronautics and Astronautics, and the Washington Space Grant Consortium.

  7. Hostility and Anger in Women with Suspected Coronary Artery Disease: The Women’s Ischemia Syndrome Evaluation (WISE) Study

    Science.gov (United States)

    2003-01-01

    dyslipidemia , low level of physical exercise , and greater likelihood of cigarette smoking. SES is therefore a well-documented CAD risk factor for...support the present observation that the relationship between Anger Out and CAD-status is only observed when history of dyslipidemia is statistically...process through which social relationships might promote health and well being (Cohen, Gottleib, & Underwood, 2000), has emerged as a significant

  8. Age-wise and gender-wise prevalence of oral habits in 7–16-year-old school children of Mewar ethnicity, India

    Directory of Open Access Journals (Sweden)

    Pradeep Vishnoi

    2017-01-01

    Full Text Available Objectives: The study aimed to check the age- and gender-wise prevalence of oral habits in the children of 7–16-year-old Indian children. Materials and Methods: A cross-sectional survey involving 1029 (661 males and 368 females children of age 7–16 years was done to record the presence or absence of the oral habits with the aid of the anamnestic questionnaire. The recorded oral habits were tongue thrusting, thumb or digit sucking, mouth breathing, bruxism, lip biting or lip sucking, and nail biting. The collected data were subjected to Pearson's Chi-square statistical analysis to know the overall difference in the prevalence rate of different oral habits and to evaluate the gender- and age-wise difference in the prevalence of oral habits. Results: Oral habits were present in 594 participants (57.73%. The highest prevalence rate was registered for tongue thrusting habit (28.8%, which was followed by nail biting (201/19.5% and thumb sucking (128/12.4%, mouth breathing (109/10.6%, lip biting (85/8.3%, and bruxism (29/2.8%. The male participants showed a greater prevalence rate for the oral habits than the female participants (58.55% vs. 56.25%. There was a significant difference in the age-wise prevalence of oral habits with older children showing greater prevalence of oral habits than the younger ones. Conclusion: The prevalence of oral habits in the current group of children is high. It warrants the need for the community-based educational preventive and interceptive programs to spread the awareness regarding the deleterious effects of these oral habits.

  9. WISE 2005: chronic bed rest impairs microcirculatory endothelium in women.

    Science.gov (United States)

    Demiot, Claire; Dignat-George, Françoise; Fortrat, Jacques-Olivier; Sabatier, Florence; Gharib, Claude; Larina, Irina; Gauquelin-Koch, Guillemette; Hughson, Richard; Custaud, Marc-Antoine

    2007-11-01

    Sedentary behavior has deleterious effects on the cardiovascular system, including reduced endothelial functions. A 2-mo bed rest study in healthy women [women international space simulation for exploration (WISE) 2005 program] presented a unique opportunity to analyze the specific effects of prolonged inactivity without other vascular risk factors on the endothelium. We investigated endothelial properties before and after 56 days of bed rest in 8 subjects who performed no exercise (control group: No-EX) and in 8 subjects who regularly performed treadmill exercise in a lower body negative pressure chamber as well as resistance exercise (countermeasure group, EX). A functional evaluation of the microcirculation in the skin was assessed with laser Doppler. We studied endothelium-dependent and -independent vasodilation using iontophoresis of acetylcholine and sodium nitroprusside, respectively. We also measured circulating endothelial cells (CECs), an index of endothelial damage. In the No-EX group, endothelium-dependent vasodilation was significantly reduced (35.4 +/- 4.8% vs. 24.1 +/- 3.8%, P endothelium-dependent vasodilation and number of CECs were preserved. Our study shows that in humans prolonged bed rest causes impairment of endothelium-dependent function at the microcirculatory level, along with an increase in circulating endothelial cells. Microcirculatory endothelial dysfunction might participate in cardiovascular deconditioning, as well as in several bed rest-induced pathologies. We therefore conclude that the endothelium should be a target for countermeasures during periods of prolonged deconditioning.

  10. GridWise Standards Mapping Overview

    Energy Technology Data Exchange (ETDEWEB)

    Bosquet, Mia L.

    2004-04-01

    ''GridWise'' is a concept of how advanced communications, information and controls technology can transform the nation's energy system--across the spectrum of large scale, central generation to common consumer appliances and equipment--into a collaborative network, rich in the exchange of decision making information and an abundance of market-based opportunities (Widergren and Bosquet 2003) accompanying the electric transmission and distribution system fully into the information and telecommunication age. This report summarizes a broad review of standards efforts which are related to GridWise--those which could ultimately contribute significantly to advancements toward the GridWise vision, or those which represent today's current technological basis upon which this vision must build.

  11. The Weight Influenced Self-Esteem Questionnaire (WISE-Q): factor structure and psychometric properties.

    Science.gov (United States)

    Trottier, Kathryn; McFarlane, Traci; Olmsted, Marion P; McCabe, Randi E

    2013-01-01

    Weight-based self-esteem (WBSE) is hypothesized to be the core cognitive feature of eating disorders. The Weight Influenced Self-Esteem Questionnaire (WISE-Q) was designed to measure the influence of a negatively perceived body image on multiple dimensions of self-esteem, which we believe to be one aspect of WBSE. Study 1 sought to determine the factor structure of the WISE-Q as well as to examine the reliability and concurrent validity of WISE-Q scores among eating disorder and undergraduate student participants. In Study 2, validity was further investigated by examining changes in WISE-Q scores with treatment. The WISE-Q has two factors representing generalized and expected WBSE. Evidence of internal and test-retest reliability was found. Also, the pattern of correlations between WISE-Q scores and other constructs was in line with predictions. As expected, WISE-Q scores improved with treatment yet remained high. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Are we Utilizing our Water Resources Wisely?

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 1. Are we Utilizing our Water Resources Wisely? B P Radhakrishna. Classics Volume 21 Issue 1 January 2016 pp 93-104 ... Author Affiliations. B P Radhakrishna1. Geological Society of India, P.B. No.1922, Gavipuram P.O., Bangalore, India.

  13. Face to Face Wise Decisions Under Uncertainty

    Indian Academy of Sciences (India)

    IAS Admin

    Face to Face. This section features conversations with personalities related to science, highlighting the factors and circumstances that guided them in making the career choice to be a scientist. Wise Decisions Under Uncertainty. C R Rao talks to B V Rajarama Bhat. Calyampudi Radhakrishna Rao is a living legend known ...

  14. LBA Regional Derived Soil Properties, 0.5-Deg (ISRIC-WISE)

    Data.gov (United States)

    National Aeronautics and Space Administration — The data set consists of a subset of the ISRIC-WISE global data set of derived soil properties for the study area of the Large Scale Biosphere-Atmosphere Experiment...

  15. Usability testing of AsthmaWise with older adults.

    Science.gov (United States)

    Burns, Pippa; Jones, Sandra C; Iverson, Don; Caputi, Peter

    2013-05-01

    There are many reasons why online self-management education is attractive to both patients and providers. AsthmaWise, an online self-management program, was developed using a Moodle platform, to enable older adults to learn asthma self-management skills. This study aimed to improve AsthmaWise through conducting: usability testing with a sample of end users; a cognitive walk-through undertaken by an independent health researcher; and assessment of content readability. A Perceived Health Web Site Usability Questionnaire score of 67% was achieved, indicating that there were usability issues that needed to be addressed. The cognitive walk-through and readability assessment identified unique issues that were not identified through usability testing with end users. The testing process allowed issues to be identified and rectified before piloting AsthmaWise, creating a more accessible and refined end product. The involvement of the site designer in the testing process was valuable and is highly recommended. This study shows that usability testing involving both end users and experts is an essential part of the design process that is relatively easy and inexpensive to undertake and can be effectively conducted by a nonexpert.

  16. Sustainable Materials Management (SMM) WasteWise Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — EPA’s WasteWise encourages organizations and businesses to achieve sustainability in their practices and reduce select industrial wastes. WasteWise is part of EPA’s...

  17. Fingerponds: seasonal integrated aquaculture in East African freshwater wetlands exploring their potential for wise use strategies

    OpenAIRE

    J. Kipkemboi

    2006-01-01

    This study was stimulated by the need for an integrated approach in wetland wise use. Sustainable management is critical for long-term ecosystem health and people's livelihoods. The potential for smallholder integrated agriculture-aquaculture as one of the possible wetland wise use strategies was explored in two sites on the northern Kenyan shores of Lake Victoria: Kusa and Nyangera.Most riparian communities living along the shores of Lake Victoria rely on wetland farming or harvesting of nat...

  18. Choosing wisely-where is the choice?

    Directory of Open Access Journals (Sweden)

    Robbins RA

    2013-06-01

    Full Text Available No abstract available. Article truncated at 150 words. A little over a year ago an editorial was posted in the Southwest Journal about the Choosing Wisely campaign from the American Board of Internal Medicine and Consumer Reports (1. You may remember that Choosing Wisely announced a list of procedures or treatments that patients should question (2. In the editorial we wondered why pulmonary organizations such as the American Thoracic Society (ATS and the American College of Chest Physicians authored none of the recommendations and offered 10 suggestions. We also openly questioned if the recommendations were intended to improve patient care or reduce costs, and thus improve the profits of third party carriers. We can now report that recommendations were announced at the recent ATS meeting in Philadelphia. Seven recommendations were made for critical care and seven for pulmonary disease. Five from the critical care list and five from the pulmonary list will eventually be chosen for inclusion in …

  19. WISE - User Guide and Implementation Notes

    CERN Document Server

    Hagen, P

    2008-01-01

    The goal of WISE is to prepare as accurately as possible the description of the LHC magnetic and geometric properties for use by the MAD-X model of the machine. WISE is designed to take into account the best estimate of uncertainties. The reason being that magnetic and geometric measurements have error bars associated with them, like calibration and resolution. Therefore WISE produces a number of instances of the most likely LHC machine that may be used to predict ranges of beam parameters. Magnetic and geometric data are downloaded from the different databases, missing information is completed, and uncertainties are added. This report contains a short section on how using the code and a detailed description of how data relative to magnetic and geometric imperfections, and slot allocation are prepared. The code is built as a transparent box, thus allowing inspection of all the information acquired during the production and test of the LHC magnets. The user interface offers a range of options that allow testin...

  20. The most luminous heavily obscured quasars have a high merger fraction: morphological study of wise -selected hot dust-obscured galaxies

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Lulu; Gao, Ying; Zhang, Dandan; Jiang, Xiaoming; Wu, Qiaoqian; Yang, Jun; Li, Zhao [Shandong Provincial Key Lab of Optical Astronomy and Solar-Terrestrial Environment, Institute of Space Science, Shandong University, Weihai 264209 (China); Han, Yunkun [Yunnan Observatories, Chinese Academy of Sciences, Kunming 650011 (China); Fang, Guanwen, E-mail: llfan@sdu.edu.cn, E-mail: hanyk@ynao.ac.cn [Institute for Astronomy and History of Science and Technology, Dali University, Dali 671003 (China)

    2016-05-10

    Previous studies have shown that Wide-field Infrared Survey Explorer -selected hyperluminous, hot dust-obscured galaxies (Hot DOGs) are powered by highly dust-obscured, possibly Compton-thick active galactic nuclei (AGNs). High obscuration provides us a good chance to study the host morphology of the most luminous AGNs directly. We analyze the host morphology of 18 Hot DOGs at z ∼ 3 using Hubble Space Telescope /WFC3 imaging. We find that Hot DOGs have a high merger fraction (62 ± 14%). By fitting the surface brightness profiles, we find that the distribution of Sérsic indices in our Hot DOG sample peaks around 2, which suggests that most Hot DOGs have transforming morphologies. We also derive the AGN bolometric luminosity (∼10{sup 14} L {sub ⊙}) of our Hot DOG sample by using IR spectral energy distributions decomposition. The derived merger fraction and AGN bolometric luminosity relation is well consistent with the variability-based model prediction. Both the high merger fraction in an IR-luminous AGN sample and relatively low merger fraction in a UV/optical-selected, unobscured AGN sample can be expected in the merger-driven evolutionary model. Finally, we conclude that Hot DOGs are merger-driven and may represent a transit phase during the evolution of massive galaxies, transforming from the dusty starburst-dominated phase to the unobscured QSO phase.

  1. Assessment of village-wise groundwater draft for irrigation: a field-based study in hard-rock aquifers of central India

    Science.gov (United States)

    Ray, R. K.; Syed, T. H.; Saha, Dipankar; Sarkar, B. C.; Patre, A. K.

    2017-07-01

    Extracted groundwater, 90% of which is used for irrigated agriculture, is central to the socio-economic development of India. A lack of regulation or implementation of regulations, alongside unrecorded extraction, often leads to over exploitation of large-scale common-pool resources like groundwater. Inevitably, management of groundwater extraction (draft) for irrigation is critical for sustainability of aquifers and the society at large. However, existing assessments of groundwater draft, which are mostly available at large spatial scales, are inadequate for managing groundwater resources that are primarily exploited by stakeholders at much finer scales. This study presents an estimate, projection and analysis of fine-scale groundwater draft in the Seonath-Kharun interfluve of central India. Using field surveys of instantaneous discharge from irrigation wells and boreholes, annual groundwater draft for irrigation in this area is estimated to be 212 × 106 m3, most of which (89%) is withdrawn during non-monsoon season. However, the density of wells/boreholes, and consequent extraction of groundwater, is controlled by the existing hydrogeological conditions. Based on trends in the number of abstraction structures (1982-2011), groundwater draft for the year 2020 is projected to be approximately 307 × 106 m3; hence, groundwater draft for irrigation in the study area is predicted to increase by ˜44% within a span of 8 years. Central to the work presented here is the approach for estimation and prediction of groundwater draft at finer scales, which can be extended to critical groundwater zones of the country.

  2. Assessment of village-wise groundwater draft for irrigation: a field-based study in hard-rock aquifers of central India

    Science.gov (United States)

    Ray, R. K.; Syed, T. H.; Saha, Dipankar; Sarkar, B. C.; Patre, A. K.

    2017-12-01

    Extracted groundwater, 90% of which is used for irrigated agriculture, is central to the socio-economic development of India. A lack of regulation or implementation of regulations, alongside unrecorded extraction, often leads to over exploitation of large-scale common-pool resources like groundwater. Inevitably, management of groundwater extraction (draft) for irrigation is critical for sustainability of aquifers and the society at large. However, existing assessments of groundwater draft, which are mostly available at large spatial scales, are inadequate for managing groundwater resources that are primarily exploited by stakeholders at much finer scales. This study presents an estimate, projection and analysis of fine-scale groundwater draft in the Seonath-Kharun interfluve of central India. Using field surveys of instantaneous discharge from irrigation wells and boreholes, annual groundwater draft for irrigation in this area is estimated to be 212 × 106 m3, most of which (89%) is withdrawn during non-monsoon season. However, the density of wells/boreholes, and consequent extraction of groundwater, is controlled by the existing hydrogeological conditions. Based on trends in the number of abstraction structures (1982-2011), groundwater draft for the year 2020 is projected to be approximately 307 × 106 m3; hence, groundwater draft for irrigation in the study area is predicted to increase by ˜44% within a span of 8 years. Central to the work presented here is the approach for estimation and prediction of groundwater draft at finer scales, which can be extended to critical groundwater zones of the country.

  3. Computer-assisted glucose regulation during rapid step-wise increases of parenteral nutrition in critically ill patients: a proof of concept study.

    Science.gov (United States)

    Hoekstra, Miriam; Schoorl, Michiel A; van der Horst, Iwan C C; Vogelzang, Mathijs; Wietasch, J K Götz; Zijlstra, Felix; Nijsten, Maarten W N

    2010-01-01

    Early delivery of calories is important in critically ill patients, and the administration of parenteral nutrition (PN) is sometimes required to achieve this goal. However, PN can induce acute hyperglycemia, which is associated with adverse outcome. We hypothesized that initiation of PN using a rapid "step-up" approach, coupled with a computerized insulin-dosing protocol, would result in a desirable caloric intake within 24 hours without causing hyperglycemia. In our surgical intensive care unit (ICU), glucose is regulated by a nurse-centered computerized glucose regulation program. When adequate enteral feeding was not possible, PN was initiated according to a simple step-up rule at an infusion rate of 10 mL/h (approximately 10 kcal/h) and subsequently increased by steps of 10 mL/h every 4 hours, provided glucose was up period and for 24 hours after achieving target feeding. In all 23 consecutive patients requiring PN, mean intake was 1 kcal/kg/h within 24 hours. Of the 280 glucose samples during the 48-hour study period, mean ± standard deviation glucose level was 7.4 ± 1.4 mmol/L. Only 4.5% of glucose measurements during the step-up period were transiently ≥10 mmol/L. After initiating PN, the insulin requirement rose from 1.1 ± 1.5 units/h to 2.9 ± 2.5 units/h (P initiation of PN using a step-up approach coupled with computerized glucose control resulted in adequate caloric intake within 24 hours while maintaining adequate glycemic control.

  4. Decoupled Block-Wise ILU(k) Preconditioner on GPU

    OpenAIRE

    Yang, Bo; Liu, Hui; Zhong, He; Chen, Zhangxin

    2017-01-01

    This research investigates the implementation mechanism of block-wise ILU(k) preconditioner on GPU. The block-wise ILU(k) algorithm requires both the level k and the block size to be designed as variables. A decoupled ILU(k) algorithm consists of a symbolic phase and a factorization phase. In the symbolic phase, a ILU(k) nonzero pattern is established from the point-wise structure extracted from a block-wise matrix. In the factorization phase, the block-wise matrix with a variable block size ...

  5. Photovoltaic evaluation study

    Science.gov (United States)

    Johnson, G.; Heikkilae, M.; Melasuo, T.; Spanner, S.

    Realizing the value and potential of PV-power as well as the growing need for increased cooperation and sharing of knowledge in the field of photovoltaics, FINNIDA and UNICEF decided to undertake a study of selected PV-projects. There were two main objectives for the study: To gather, compile, evaluate and share information on the photovoltaic technology appropriate to developing countries, and to promote the interest and competence of Finnish research institutes, consultants and manufacturers in photovoltaic development. For this purpose a joint evaluation of significant, primarily UN-supported projects providing for the basic needs of rural communities was undertaken. The Gambia and Kenya offered a variety of such projects, and were chosen as target countries for the study. The projects were chosen to be both comparable and complimentary. In the Gambia, the main subject was a partially integrated health and telecommunications project, but a long-operating drinking water pumping system was also studied. In Kenya, a health project in the Turkana area was examined, and also a large scale water pumping installation for fish farming. Field visits were made in order to verify and supplement the data gathered through document research and earlier investigations. Individual data gathering sheets for the project form the core of this study and are intended to give the necessary information in an organized and accessible format. The findings could practically be condensed into one sentence: PV-systems work very well, if properly designed and installed, but the resources and requirements of the recipients must be considered to a higher degree.

  6. Do choosing wisely tools meet criteria for patient decision aids? A descriptive analysis of patient materials.

    Science.gov (United States)

    Légaré, France; Hébert, Jessica; Goh, Larissa; Lewis, Krystina B; Leiva Portocarrero, Maria Ester; Robitaille, Hubert; Stacey, Dawn

    2016-08-26

    Choosing Wisely is a remarkable physician-led campaign to reduce unnecessary or harmful health services. Some of the literature identifies Choosing Wisely as a shared decision-making approach. We evaluated the patient materials developed by Choosing Wisely Canada to determine whether they meet the criteria for shared decision-making tools known as patient decision aids. Descriptive analysis of all Choosing Wisely Canada patient materials. In May 2015, we selected all Choosing Wisely Canada patient materials from its official website. Four team members independently extracted characteristics of the English materials using the International Patient Decision Aid Standards (IPDAS) modified 16-item minimum criteria for qualifying and certifying patient decision aids. The research team discussed discrepancies between data extractors and reached a consensus. Descriptive analysis was conducted. Of the 24 patient materials assessed, 12 were about treatments, 11 were about screening and 1 was about prevention. The median score for patient materials using IPDAS criteria was 10/16 (range: 8-11) for screening topics and 6/12 (range: 6-9) for prevention and treatment topics. Commonly missed criteria were stating the decision (21/24 did not), providing balanced information on option benefits/harms (24/24 did not), citing evidence (24/24 did not) and updating policy (24/24 did not). Out of 24 patient materials, only 2 met the 6 IPDAS criteria to qualify as patient decision aids, and neither of these 2 met the 6 certifying criteria. Patient materials developed by Choosing Wisely Canada do not meet the IPDAS minimal qualifying or certifying criteria for patient decision aids. Modifications to the Choosing Wisely Canada patient materials would help to ensure that they qualify as patient decision aids and thus as more effective shared decision-making tools. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to

  7. THE WISE LIGHT CURVES OF POLARS

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Thomas E. [Department of Astronomy, New Mexico State University, Box 30001, MSC 4500, Las Cruces, NM 88003-8001 (United States); Campbell, Ryan K., E-mail: tharriso@nmsu.edu, E-mail: Ryan.Campbell@humboldt.edu [Department of Physics and Astronomy, Humboldt State University, 1 Harpst St., Arcata, CA 95521 (United States)

    2015-08-15

    We have extracted the WISE (Wide-field Infrared Survey Explorer) single-exposure data for a sample of 72 polars, which are highly magnetic cataclysmic variables (CVs). We combine these data with both published and unpublished optical and infrared data to explore the origins of the large amplitude variations seen in these systems. In nearly every case, we find evidence for cyclotron emission in the WISE bandpasses. We find that the derived magnetic field strengths for some polars are either too high, or cyclotron emission from lower field components, located spatially coincident to the main accreting poles, must be occurring. We have also estimated field strengths for a number of polars where no such values exist. In addition, contrary to expectations, we find that emission from the fundamental cyclotron harmonic (n = 1) appears to be nearly always present when the magnetic field is of the appropriate strength that it falls within a WISE bandpass. We find that the light curves for RBS 490, an ultrashort-period (46 minutes) CV, suggest that it is a polar. Modeling its spectrum indicates that its donor star is much hotter than expected. Nearly all of the detected polars show 11.5 μm (“W3 band”) excesses. The general lack of variability seen in the W3 bandpass light curves for higher-field polars demonstrates that these excesses are probably not due to cyclotron emission. There is circumstantial evidence that these excesses can be attributed to bremsstrahlung emission from their accretion streams. Reduction of the Spitzer 24 μm image of V1500 Cyg shows that it appears to be located at the center of a small nebula.

  8. Wise Detections of Known QSOS at Redshifts Greater Than Six

    Science.gov (United States)

    Blain, Andrew W.; Assef, Roberto; Stern, Daniel; Tsai, Chao-Wei; Eisenhardt, Peter; Bridge, Carrie; Benford, Dominic; Jarrett, Tom; Cutri, Roc; Petty, Sara; hide

    2013-01-01

    We present WISE All-Sky mid-infrared (IR) survey detections of 55 % (17/31) of the known QSOs at z greater than 6 from a range of surveys: the SDSS, the CFHT-LS, FIRST, Spitzer and UK1DSS. The WISE catalog thus provides a substantial increase in tiie quantity of IR data available for these sources: 17 are detected in the WISE Wl (3.4 micrometer) band, 16 in W2 (4.6 micrometers), 3 in W3 (12 micrometers) and 0 in W4 (22micrometers). This is particularly important with Spitzer in its warm-mission phase and no faint follow-up capability at wavelengths longwards of 5 micrometers until the launch of JWST. WISE thus provides a useful tool for understanding QSOs found in forthcoming large-area optical/IR sky surveys, using PanSTARRS, SkyMapper, VISTA, DES and LSST. The rest-UV properties of the WISE-detected and the WISE-non-detected samples differ: the detections have brighter i/z-band magnitudes and redder rest-UV colors. This suggests thai a more aggressive hunt for very-high-redshift QSOs, by combining WISE Wl and W2 data with red observed optical colors could be effective at least, for a subset of dusty candidate QSOs. Stacking the WISE images of the WISE-non-detected QSOs indicates that they are on average significantly fainter than the WISE-detccted examples, and are thus not narrowly missing detection in the WISE catalog. The WISE-catalog detection of three of our sample in the W3 band indicates that their mid-ID flux can be detected individually, although there is no stacked W3 detection of sources detected in Wl but not. W3. Stacking analyses of WISE data for large AGN samples will be a useful tool, and high-redshifl. QSOs of all types will be easy targets for JWST.

  9. The Wisdom in Virtue: Pursuit of Virtue Predicts Wise Reasoning About Personal Conflicts.

    Science.gov (United States)

    Huynh, Alex C; Oakes, Harrison; Shay, Garrett R; McGregor, Ian

    2017-09-01

    Most people can reason relatively wisely about others' social conflicts, but often struggle to do so about their own (i.e., Solomon's paradox). We suggest that true wisdom should involve the ability to reason wisely about both others' and one's own social conflicts, and we investigated the pursuit of virtue as a construct that predicts this broader capacity for wisdom. Results across two studies support prior findings regarding Solomon's paradox: Participants ( N = 623) more strongly endorsed wise-reasoning strategies (e.g., intellectual humility, adopting an outsider's perspective) for resolving other people's social conflicts than for resolving their own. The pursuit of virtue (e.g., pursuing personal ideals and contributing to other people) moderated this effect of conflict type. In both studies, greater endorsement of the pursuit of virtue was associated with greater endorsement of wise-reasoning strategies for one's own personal conflicts; as a result, participants who highly endorsed the pursuit of virtue endorsed wise-reasoning strategies at similar levels for resolving their own social conflicts and resolving other people's social conflicts. Implications of these results and underlying mechanisms are explored and discussed.

  10. Uncovering Heavily Obscured AGN with WISE and NuSTAR

    Science.gov (United States)

    Hickox, Ryan C.; Carroll, Christopher M.; Yan, Wei; DiPompeo, Michael A.; Hainline, Kevin N.; NuSTAR Obscured AGN Team

    2018-01-01

    Supermassive black holes gain their mass through accretion as active galactic nuclei (AGN), but it is now clear that a large fraction of this growth is "hidden" behind large columns of gas and dust. Of particular interest are Compton-thick (CT) AGN, with columns NH > 1024 cm-2, that have been difficult to identify using optical or soft X-ray surveys. We will present two studies of heavily obscured AGN that aim to uncover more of the full population of "hidden" growing black holes: (1) Analysis of the spectral energy distributions of millions of galaxies with photometry from WISE (mid-IR), UKIDSS (near-IR), and SDSS (optical), that uncovers large populations of weak or heavily buried AGN, and (2) NuSTAR observations of a sample of candidate highly obscured AGN, selected from WISE and SDSS photometry,and confirmed using SALT and Keck spectroscopy. The NuSTAR data reveal the existence of powerful CT quasars with extremely large columns NH > 1025 cm-2, which may represent a significant fraction of previously hidden black hole growth. This work is supported by NASA grant numbers NNX16AN48G and NNX15AP24G, and the NSF through grant numbers 1515364 and 1554584.

  11. Screening with Papanicolaou tests in Alberta: Are we Choosing Wisely?

    Science.gov (United States)

    Symonds, Christopher J; Chen, Wenxin; Rose, Marianne Sarah; Cooke, Lara J

    2018-01-01

    To describe the prevalence and geographic distribution of cervical cancer screening, as well as the age groups of those undergoing screening, in Alberta, and to determine if screening practices conform to current guidelines and follow Choosing Wisely Canada recommendations. Descriptive study using data from the Alberta Ministry of Health Analytics and Performance Reporting Branch. Alberta. Women who had 1 or more Papanicolaou tests between 2011 and 2013. Number of women aged 15 to 20 and those aged 70 and older who had 1 or more Pap tests in a 3-year period; year-to-year trends in screening rates for women in these 2 age groups; trends in screening rates in various geographic regions (ie, cities and zones) in Alberta; and the discipline of clinicians who ordered the Pap tests. Between 2011 and 2013, 805 632 women in the province of Alberta had 1 or more Pap tests for cervical cancer screening. Overall, 25 511 (17.5%) women aged 15 to 20 and 16 818 (10.3%) aged 70 and older were screened contrary to most existing guidelines. Screening rates varied markedly in different geographic regions of the province. Most Pap tests were ordered by family physicians or general practitioners. Within the geographic regions of Alberta, provincial, national, and international guidelines for screening with Pap tests are inconsistently followed. This strongly echoes the need for clinicians and patients to consider the Choosing Wisely Canada recommendations and current guidelines for cervical cancer screening. Copyright© the College of Family Physicians of Canada.

  12. A lattice implementation of the Isgur-Wise limit

    Science.gov (United States)

    Mandula, Jeffrey E.; Ogilvie, Michael C.

    We construct the Isgur-Wise limit of QCD in a form appropriate for lattice gauge theory. The formulation permits a calculation of heavy quark processes even when the momentum transfers are much larger than the inverse lattice spacing. Applications include semi-leptonic heavy quark decay and scattering processes, including the computation of the nonperturbative part of the Isgur-Wise universal function.

  13. Progress in Documentation. WISE: A World Information Synthesis and Encyclopaedia

    Science.gov (United States)

    Kochen, Manfred

    1972-01-01

    World Information Synthesis and Encyclopaedia (WISE), is a modernized version of H. G. Wells' World Brain'' concept. The desirability and feasibility of WISE are argued. World mental health through world mental wealth is far too important an idea to be left dormant, undiscussed and unexplored. (48 references) (Author/NH)

  14. The eShel Spectrograph: A Radial-velocity Tool at the Wise Observatory

    Science.gov (United States)

    Engel, M.; Shahaf, S.; Mazeh, T.

    2017-06-01

    The eShel, an off-the-shelf, fiber-fed echelle spectrograph (R≈ {{10,000}}), was installed on the 1 m telescope at the Wise observatory in Israel. We report the installation of the multi-order spectrograph, and describe our pipeline to extract stellar radial velocity from the obtained spectra. We also introduce a new algorithm—UNICOR, to remove radial-velocity systematics that can appear in some of the observed orders. We show that the system performance is close to the photon-noise limit for exposures with more than 107 counts, with a precision that can get better than 200 m s-1 for F-K stars, for which the eShel spectral response is optimal. This makes the eShel at Wise a useful tool for studying spectroscopic binaries brighter than m V = 11. We demonstrate this capability with orbital solutions of two binaries from projects being performed at Wise.

  15. Structural integration of separation and reaction systems: I. Integration of stage-wise processes

    Directory of Open Access Journals (Sweden)

    Mitrović Milan

    2002-01-01

    Full Text Available The structural integration of separation processes, using multifunctional equipment, has been studied on four stage-wise liquid-liquid separations extraction, absorption, distillation, adsorption and on some combinations of these processes. It was shown for stage - wise processes that the ultimate aim of equipment integration is 3-way integration (by components by steps and by stages and that membrane multiphase contactors present concerning the equipment optimal solutions in many cases. First, by using partially integrated equipment and, later by developing fully integrated systems it was experimentally confirmed that structural 3-way integration produces much higher degrees of component separations and component enrichments in compact and safe equipment.

  16. Photon absorption in step-wise multi-photon activation fluorescence (SMPAF) of Sepia melanin

    Science.gov (United States)

    Lai, Zhenhua; Kerimo, Josef; DiMarzio, Charles

    2013-02-01

    Previous research has shown that melanin goes through a step-wise three-photon absorption process when the fluorescence is activated with high laser intensity. We have conducted further research using even higher laser intensity for the activation, and have shown the possibility of observing power dependence other than third-order. This article discusses the possible energy states of Sepia melanin by studying the power dependence curves of the step-wise multi-photon activated fluorescence signal. Three different excitation channels are activated. Possible reasons causing the three channels are discussed.

  17. Menses cup evaluation study.

    Science.gov (United States)

    Cheng, M; Kung, R; Hannah, M; Wilansky, D; Shime, J

    1995-09-01

    To determine whether the menses cup is well tolerated by menstruating women. Prospective descriptive clinical study. Normal human volunteers in an academic research environment. Fifty-one menstruating women recruited between June to December 1991. Each participant was provided with two menses cups and an instruction sheet. Baseline information, including age, occupation, martial status, parity, description of menstrual flow, and current method used to cope with menstrual flow was collected. Subjects were asked to describe their experience with the cup at 1-, 2-, 6-, and 12-month intervals. The proportion of women who found the cup acceptable. The cup was used by 51 subjects for a total of 159 cycles. Overall, 23 women (45%) found the cup an acceptable method for coping with menses. Among 29 (57%) women who used the cup for two or more cycles, 62% found it acceptable. The menses cup may be an acceptable method for some women for coping with menstrual flow.

  18. The WISE Satellite Development: Managing the Risks and the Opportunities

    Science.gov (United States)

    Duval, Valerie G.; Elwell, John D.; Howard, Joan F.; Irace, William R.; Liu, Feng-Chuan

    2010-01-01

    NASA's Wide-field Infrared Survey Explorer (WISE) MIDEX mission is surveying the entire sky in four infrared bands from 3.4 to 22 micrometers. The WISE instrument consists of a 40 cm telescope, a solid hydrogen cryostat, a scan mirror mechanism, and four 1K x1K infrared detectors. The WISE spacecraft bus provides communication, data handling, and avionics including instrument pointing. A Delta 7920 successfully launched WISE into a Sun-synchronous polar orbit on December 14, 2009. WISE was competitively selected by NASA as a Medium cost Explorer mission (MIDEX) in 2002. MIDEX missions are led by the Principal Investigator who delegates day-to-day management to the Project Manager. Given the tight cost cap and relatively short development schedule, NASA chose to extend the development period one year with an option to cancel the mission if certain criteria were not met. To meet this and other challenges, the WISE management team had to learn to work seamlessly across institutional lines and to recognize risks and opportunities in order to develop the flight hardware within the project resources. In spite of significant technical issues, the WISE satellite was delivered on budget and on schedule. This paper describes our management approach and risk posture, technical issues, and critical decisions made.

  19. Planck intermediate results XXIX. All-sky dust modelling with Planck, IRAS, and WISE observations

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.

    2016-01-01

    We present all-sky modelling of the high resolution Planck, IRAS, andWISE infrared (IR) observations using the physical dust model presented by Draine & Li in 2007 (DL, ApJ, 657, 810). We study the performance and results of this model, and discuss implications for future dust modelling. The pres...

  20. Lattice implementation of the Isgur-Wise limit

    Science.gov (United States)

    Mandula, Jeffrey E.; Ogilvie, Michael C.

    1992-04-01

    We construct the Isgur-Wise limit of QCD in a form appropriate for measurement by lattice-gauge-theory techniques. The coordinate-space fermion propagator in the presence of a background gauge field has a systematic expansion in powers of the inverse quark mass about the Isgur-Wise limit. The formulation permits a calculation of heavy-quark processes even when the momentum transfers are much larger than the inverse lattice spacing. Applications include semileptonic heavy-quark decay and scattering processes, including the computation of the nonperturbative part of the Isgur-Wise universal function.

  1. The Level of Test-Wiseness for the Students of Arts and Science Faculty at Sharourah and Its Relationship with Some Variables

    Science.gov (United States)

    Otoum, Abedalqader; Khalaf, Hisham Bani; Bajbeer, Abedalqader; Hamad, Hassan Bani

    2015-01-01

    This study aimed to identify the level of using Test-wiseness strategies for the students of arts and sciences Faculty at Sharourah and its relationship with some variables. a questionnaire was designed which consisted of (29) items measuring three domains of Test-wiseness strategies. It was applied on a sample which consisted of (299) students.…

  2. Tuberculosis care: an evaluability study

    Science.gov (United States)

    Coelho, Ardigleusa Alves; Martiniano, Cláudia Santos; Brito, Ewerton Willian Gomes; Negrão, Oswaldo Gomes Corrêa; Arcêncio, Ricardo Alexandre; Uchôa, Severina Alice da Costa

    2014-01-01

    OBJECTIVE: to verify whether the tuberculosis control program (TCP) is evaluable and to examine the feasibility of building an evaluation model in apriority municipality for the control of tuberculosis. METHOD: this evaluability study was conducted in a municipality in northeastern Brazil. For data collection, documental analysis and interviews with key informants were performed. For indicator validation, the nominal group technique was adopted. RESULTS: the details of TCP were described, and both the logical model and the classification framework for indicators were developed and agreed up on, with the goal of characterizing the structural elements of the program, defining the structure and process indicators, and formulating the evaluation questions. CONCLUSION: TCP is evaluable. Based on logical operational analysis, it was possible to evaluate the adequacy of the program goals for the control of tuberculosis. Therefore, the performance of a summative evaluation is recommended, with a focus on the analysis of the effects of tuberculosis control interventions on decreasing morbidity and mortality. PMID:25493675

  3. Mid-infrared Excess from the West Hot Spot of the Radio Galaxy Pictor A Unveiled by WISE

    Science.gov (United States)

    Isobe, Naoki; Koyama, Shoko; Kino, Motoki; Wada, Takehiko; Nakagawa, Takao; Matsuhara, Hideo; Niinuma, Kotaro; Tashiro, Makoto

    2017-12-01

    Mid-infrared properties are reported of the west hot spot of the radio galaxy Pictor A with the Wide-field Infrared Survey Explorer (WISE). The mid-infrared counterpart to the hot spot, WISE J051926.26‑454554.1, is listed in the AllWISE source catalog. The source was detected in all four of the WISE photometric bands. A comparison between the WISE and radio images reinforces the physical association of the WISE source to the hot spot. The WISE flux density of the source was carefully evaluated. A close investigation of the multi-wavelength synchrotron spectral energy distribution from the object reveals a mid-infrared excess at the wavelength of λ =22 μm with a statistical significance of 4.8σ over the simple power-law extrapolation from the synchrotron radio spectrum. The excess is reinforced by single and double cutoff power-law modeling of the radio-to-optical spectral energy distribution. The synchrotron cutoff frequency of the main and excess components was evaluated as 7.1× {10}14 Hz and 5.5× {10}13 Hz, respectively. From the cutoff frequency, the magnetic field of the emission region was constrained as a function of the region size. In order to interpret the excess component, an electron population different from the main one dominating the observed radio spectrum is necessary. The excess emission is proposed to originate in a substructure within the hot spot, in which the magnetic field is a factor of a few stronger than that in the minimum-energy condition. The relation of the mid-infrared excess to the X-ray emission is briefly discussed.

  4. The Isgur-Wise limit on the lattice

    Science.gov (United States)

    Mandula, Jeffrey E.; Ogilvie, Michael C.

    1993-03-01

    We construct the Isgur-Wise limit of QCD in a form appropriate to lattice gauge theory techniques. The formulation permits a calculation of heavy quark processes even when the momentum transfers are much larger than the inverse lattice spacing. Applications include semi-leptonic heavy quark decay and scattering processes, including the computation of the nonperturbative part of the Isgur-Wise universal function.

  5. The Isgur-Wise limit on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Mandula, J.E. (Dept. of Energy, Div. of High Energy Physics, Washington, DC (United States)); Ogilvie, M.C. (Dept. of Physics, Washington Univ., St. Louis, MO (United States))

    1993-03-01

    We construct the Isgur-Wise limit of QCD in a form appropriate to lattice gauge theory techniques. The formulation permits a calculation of heavy quark processes even when the momentum transfers are much larger than the inverse lattice spacing. Applications include semi-leptonic heavy quark decay and scattering processes, including the computation of the nonperturbative part of the Isgur-Wise universal function. (orig.)

  6. A lattice implementation of the Isgur-Wise limit

    Energy Technology Data Exchange (ETDEWEB)

    Mandula, J.E. (Department of Energy, Washington, DC (United States). Div. of High Energy Physics); Ogilvie, M.C. (Washington Univ., St. Louis, MO (United States). Dept. of Physics)

    1992-05-01

    We construct the Isgur-Wise limit of QCD in a form appropriate for lattice gauge theory. The formulation permits a calculation of heavy quark processes even when the momentum transfers are much larger than the inverse lattice spacing. Applications include semi-leptonic heavy quark decay and scattering processes, including the computation of the nonperturbative part of the Isgur-Wise universal function. (orig.).

  7. Four-Dimensional Coded Modulation with Bit-wise Decoders for Future Optical Communications

    CERN Document Server

    Alvarado, Alex

    2014-01-01

    Coded modulation (CM) is the combination of forward error correction (FEC) and multilevel constellations. Coherent optical communication systems result in a four-dimensional (4D) signal space, which naturally leads to 4D-CM transceivers. A practically attractive design paradigm is to use a bit-wise decoder, where the detection process is (suboptimally) separated into two steps: soft-decision demapping followed by binary decoding. In this paper, bit-wise decoders are studied from an information-theoretic viewpoint. 4D constellations with up to 4096 constellation points are considered. Metrics to predict the post-FEC bit-error rate (BER) of bit-wise decoders are analyzed. The mutual information is shown to fail at predicting the post-FEC BER of bit-wise decoders and the so-called generalized mutual information is shown to be a much more robust metric. It is also shown that constellations that transmit and receive information in each polarization and quadrature independently (e.g., PM-QPSK, PM-16QAM, and PM-64QA...

  8. Infrared excesses in stars with and without planets using revised WISE photometry

    Science.gov (United States)

    Maldonado, Raul F.; Chavez, Miguel; Bertone, Emanuele; Cruz-Saenz de Miera, Fernando

    2017-11-01

    We present an analysis on the potential prevalence of mid-infrared excesses in stars with and without planetary companions. Based on an extended data base of stars detected with the Wide Infrared Survey Explorer (WISE) satellite, we studied two stellar samples: one with 236 planet hosts and another with 986 objects for which planets have been searched, but not found. We determined the presence of an excess over the photosphere by comparing the observed flux ratio at 22 and 12 μm (f22/f12) with the corresponding synthetic value, derived from results of classical model photospheres. We found a detection rate of 0.85 per cent at 22 μm (two excesses) in the sample of stars with planets and 0.1 per cent (1 detection) for the stars without planets. The difference of the detection rate between the two samples is not statistically significant, a result that is independent of the different approaches found in the literature to define an excess in the wavelength range covered by WISE observations. As an additional result, we found that the WISE fluxes required a normalization procedure to make them compatible with synthetic data, probably pointing out a revision of the WISE data calibration.

  9. Sustainable Materials Management (SMM) WasteWise Data

    Science.gov (United States)

    EPA??s WasteWise encourages organizations and businesses to achieve sustainability in their practices and reduce select industrial wastes. WasteWise is part of EPA??s sustainable materials management efforts, which promote the use and reuse of materials more productively over their entire lifecycles. All U.S. businesses, governments and nonprofit organizations can join WasteWise as a partner, endorser or both. Current participants range from small local governments and nonprofit organizations to large multinational corporations. Partners demonstrate how they reduce waste, practice environmental stewardship and incorporate sustainable materials management into their waste-handling processes. Endorsers promote enrollment in WasteWise as part of a comprehensive approach to help their stakeholders realize the economic benefits to reducing waste. WasteWise helps organizations reduce their impact on global climate change through waste reduction. Every stage of a product's life cycle??extraction, manufacturing, distribution, use and disposal??indirectly or directly contributes to the concentration of greenhouse gases (GHGs) in the atmosphere and affects the global climate. WasteWise is part of EPA's larger SMM program (https://www.epa.gov/smm). Sustainable Materials Management (SMM) is a systemic approach to using and reusing materials more productively over their entire lifecycles. It represents a change in how our society thinks about the use of natural resources

  10. Impact of Antibiotic Shortage on H. Pylori Treatment: A Step-Wise Approach for Pharmacist Management

    Directory of Open Access Journals (Sweden)

    Ann Lloyd, Pharm.D., BCPS

    2013-01-01

    Full Text Available The current drug shortage crisis involving multiple oral antibiotics has significantly impacted preferred therapeutic options for treatment of H.pylori infection. Pharmacists may help alleviate the impact of this shortage through a proposed step-wise approach which includes proper inventory management, verification of indication, evaluation of regimen, therapeutic monitoring, and communication with patients and providers regarding alternative therapy or symptomatic relief.

  11. Galaxy and Mass Assembly (GAMA): Exploring the WISE Web in G12

    Science.gov (United States)

    Jarrett, T. H.; Cluver, M. E.; Magoulas, C.; Bilicki, M.; Alpaslan, M.; Bland-Hawthorn, J.; Brough, S.; Brown, M. J. I.; Croom, S.; Driver, S.; Holwerda, B. W.; Hopkins, A. M.; Loveday, J.; Norberg, P.; Peacock, J. A.; Popescu, C. C.; Sadler, E. M.; Taylor, E. N.; Tuffs, R. J.; Wang, L.

    2017-02-01

    We present an analysis of the mid-infrared Wide-field Infrared Survey Explorer (WISE) sources seen within the equatorial GAMA G12 field, located in the North Galactic Cap. Our motivation is to study and characterize the behavior of WISE source populations in anticipation of the deep multiwavelength surveys that will define the next decade, with the principal science goal of mapping the 3D large-scale structures and determining the global physical attributes of the host galaxies. In combination with cosmological redshifts, we identify galaxies from their WISE W1 (3.4 μm) resolved emission, and we also perform a star-galaxy separation using apparent magnitude, colors, and statistical modeling of star counts. The resulting galaxy catalog has ≃590,000 sources in 60 deg2, reaching a W1 5σ depth of 31 μJy. At the faint end, where redshifts are not available, we employ a luminosity function analysis to show that approximately 27% of all WISE extragalactic sources to a limit of 17.5 mag (31 μJy) are at high redshift, z> 1. The spatial distribution is investigated using two-point correlation functions and a 3D source density characterization at 5 Mpc and 20 Mpc scales. For angular distributions, we find that brighter and more massive sources are strongly clustered relative to fainter sources with lower mass; likewise, based on WISE colors, spheroidal galaxies have the strongest clustering, while late-type disk galaxies have the lowest clustering amplitudes. In three dimensions, we find a number of distinct groupings, often bridged by filaments and superstructures. Using special visualization tools, we map these structures, exploring how clustering may play a role with stellar mass and galaxy type.

  12. Insulin degludec once-daily in type 2 diabetes: simple or step-wise titration (BEGIN: once simple use).

    Science.gov (United States)

    Philis-Tsimikas, Athena; Brod, Meryl; Niemeyer, Marcus; Ocampo Francisco, Ann Marie; Rothman, Jeffrey

    2013-06-01

    Insulin degludec (IDeg) is a new basal insulin in development with a flat, ultra-long action profile that may permit dosing using a simplified titration algorithm with less frequent self-measured blood glucose (SMBG) measurements and more simplified titration steps than currently available basal insulins. This 26-week, multi-center, open-label, randomized, treat-to-target study compared the efficacy and safety of IDeg administered once-daily in combination with metformin in insulin-naïve subjects with type 2 diabetes using two different patient-driven titration algorithms: a "Simple" algorithm, with dose adjustments based on one pre-breakfast SMBG measurement (n = 111) versus a "Step-wise" algorithm, with adjustments based on three consecutive pre-breakfast SMBG values (n = 111). IDeg was administered using the FlexTouch® insulin pen (Novo Nordisk A/S, Bagsværd, Denmark), with once-weekly dose titration in both groups. Glycosylated hemoglobin (HbA1c) decreased from baseline to week 26 in both groups (-1.09%, IDegSimple; -0.93%, IDegStep-wise). IDegSimple was non-inferior to IDegStep-wise in lowering HbA1c [estimated treatment difference (IDegSimple - IDegStep-wise): -0.16% points (-0.39; 0.07)95% CI]. Fasting plasma glucose was reduced (-3.27 mmol/L, IDegSimple; -2.68 mmol/L, IDegStep-wise) with no significant difference between groups. Rates of confirmed hypoglycemia [1.60, IDegSimple; 1.17, IDegStep-wise events/patient year of exposure (PYE)] and nocturnal confirmed hypoglycemia (0.21, IDegSimple; 0.10, IDegStep-wise events/PYE) were low, with no significant differences between groups. Daily insulin dose after 26 weeks was 0.61 U/kg (IDegSimple) and 0.50 U/kg (IDegStep-wise). No significant difference in weight change was seen between groups by week 26 (+1.6 kg, IDegSimple; +1.1 kg, IDegStep-wise), and there were no clinically relevant differences in adverse event profiles. IDeg was effective and well tolerated using either the Simple or Step-wise titration

  13. Apply for 2017 WasteWise Awards

    Science.gov (United States)

    Partner and endorser awards are based on data reported in the SMM Data Management System and a narrative description of activities. Partners will be evaluated using a weighted average of evaluation criteria.

  14. Problems with step-wise regression in research on aging and recommended alternatives.

    Science.gov (United States)

    Scialfa, C T; Games, P A

    1987-11-01

    The use of step-wise regression techniques in aging research brings with it certain interpretative difficulties. Both geometric and algebraic approaches are used to demonstrate that although step-wise procedures pose little difficulty if predictors are orthogonal, these same procedures, when used with correlated predictors, can lead to poor tests of the predictor regression weights. Techniques that are useful in the detection of multicollinearity are discussed. Principal components regression, ridge regression, and hierarchical regression are evaluated as potential techniques for assessing the relative importance of predictors when these variables are correlated, as is common in aging research. Hierarchical regression is the most recommended technique in that it is theory-driven rather than dependent on empirical relations that may be sample-specific and unstable.

  15. The Glass Is Half Full: Evidence for Efficacy of Alcohol-Wise at One University But Not the Other

    Science.gov (United States)

    CROOM, KATHERINE; STAIANO-COICO, LISA; LESSER, MARTIN L.; LEWIS, DEBORAH K.; REYNA, VALERIE F.; MARCHELL, TIMOTHY C.; FRANK, JEREMY; IVES, STEPHANIE

    2017-01-01

    This research extends the growing literature about online alcohol prevention programs for first-year college students. Two independent randomized control studies, conducted at separate universities, evaluated the short-term effectiveness of Alcohol-Wise, an online alcohol prevention program not previously studied. It was hypothesized the prevention program would increase alcohol knowledge and reduce alcohol consumption, including high-risk alcohol-related behaviors, among first-year college students. At both universities, the intervention significantly increased alcohol-related knowledge. At one university, the prevention program also significantly reduced alcohol consumption and high-risk drinking behaviors, such as playing drinking games, heavy drinking, and extreme ritualistic alcohol consumption. Implications for the use of online alcohol prevention programs and student affairs are discussed. PMID:25909233

  16. Is there more valuable information in PWI datasets for a voxel-wise acute ischemic stroke tissue outcome prediction than what is represented by typical perfusion maps?

    Science.gov (United States)

    Forkert, Nils Daniel; Siemonsen, Susanne; Dalski, Michael; Verleger, Tobias; Kemmling, Andre; Fiehler, Jens

    2014-03-01

    The acute ischemic stroke is a leading cause for death and disability in the industry nations. In case of a present acute ischemic stroke, the prediction of the future tissue outcome is of high interest for the clinicians as it can be used to support therapy decision making. Within this context, it has already been shown that the voxel-wise multi-parametric tissue outcome prediction leads to more promising results compared to single channel perfusion map thresholding. Most previously published multi-parametric predictions employ information from perfusion maps derived from perfusion-weighted MRI together with other image sequences such as diffusion-weighted MRI. However, it remains unclear if the typically calculated perfusion maps used for this purpose really include all valuable information from the PWI dataset for an optimal tissue outcome prediction. To investigate this problem in more detail, two different methods to predict tissue outcome using a k-nearest-neighbor approach were developed in this work and evaluated based on 18 datasets of acute stroke patients with known tissue outcome. The first method integrates apparent diffusion coefficient and perfusion parameter (Tmax, MTT, CBV, CBF) information for the voxel-wise prediction, while the second method employs also apparent diffusion coefficient information but the complete perfusion information in terms of the voxel-wise residue functions instead of the perfusion parameter maps for the voxel-wise prediction. Overall, the comparison of the results of the two prediction methods for the 18 patients using a leave-one-out cross validation revealed no considerable differences. Quantitatively, the parameter-based prediction of tissue outcome led to a mean Dice coefficient of 0.474, while the prediction using the residue functions led to a mean Dice coefficient of 0.461. Thus, it may be concluded from the results of this study that the perfusion parameter maps typically derived from PWI datasets include all

  17. Teachers and Technology Use in Secondary Science Classrooms: Investigating the Experiences of Middle School Science Teachers Implementing the Web-based Inquiry Science Environment (WISE)

    Science.gov (United States)

    Schulz, Rachel Corinne

    This study investigated the intended teacher use of a technology-enhanced learning tool, Web-based Inquiry Science Environment (WISE), and the first experiences of teachers new to using it and untrained in its use. The purpose of the study was to learn more about the factors embedded into the design of the technology that enabled it or hindered it from being used as intended. The qualitative research design applied grounded theory methods. Using theoretical sampling and a constant comparative analysis, a document review of WISE website led to a model of intended teacher use. The experiences of four middle school science teachers as they enacted WISE for the first time were investigated through ethnographic field observations, surveys and interviews using thematic analysis to construct narratives of each teachers use. These narratives were compared to the model of intended teacher use of WISE. This study found two levels of intended teacher uses for WISE. A basic intended use involved having student running the project to completion while the teacher provides feedback and assesses student learning. A more optimal description of intended use involved the supplementing the core curriculum with WISE as well as enhancing the core scope and sequence of instruction and aligning assessment with the goals of instruction through WISE. Moreover, WISE projects were optimally intended to be facilitated through student-centered teaching practices and inquiry-based instruction in a collaborative learning environment. It is also optimally intended for these projects to be shared with other colleagues for feedback and iterative development towards improving the Knowledge Integration of students. Of the four teachers who participated in this study, only one demonstrated the use of WISE as intended in the most basic way. This teacher also demonstrated the use of WISE in a number of optimal ways. Teacher confusion with certain tools available within WISE suggests that there may be a

  18. Cold Brown Dwarfs with WISE: Y Dwarfs and the Field Mass Function

    Science.gov (United States)

    Kirkpatrick, J. Davy

    2012-01-01

    Why study Brown Dwarf stars? They re the lowest mass byproducts of star formation.. They provide time capsules across the age of the Galaxy.. They show what low-T(sub eff) atmospheres look like.. They may be some of our closest neighbors in space..WISE is a 40cm Earth-orbiting telescope. There are 211 stars and only 33 brown dwarfs in this volume.. This means that stars outnumber brown dwarfs by a factor of 6:1 currently.. The number of brown dwarfs will continue to increase if:: (a) more nearby Y dwarf candidates are confirmed, or (b) our distances to known Y s are overestimated, or (c) there are colder BDs invisible to WISE..

  19. WISE Albedos for Tens of Thousands of Main Belt Asteroids

    NARCIS (Netherlands)

    Masiero, Joseph R.; Mainzer, A. K.; Bauer, J.; Cutri, R.; Dailey, J.; Delbo, M.; Grav, T.; McMillan, R. S.; Mueller, M.; Walker, R.; Wright, E.; WISE Science Team, [No Value

    2010-01-01

    Using thermal IR data from the Wide-field Infrared Survey Explorer (WISE) mission we have calculated diameters for tens of thousands of previously known Main Belt asteroids. Using archival optical observations we have also determined albedos for each object. We present our results from this

  20. The Wise Fool Djuha – a Quick Sketch

    Directory of Open Access Journals (Sweden)

    George Grigore

    2014-12-01

    Full Text Available This paper entitled The wise fool Djuha – a quick sketch presents the origin of the very known hero of Arabic folk literature, Djuha, the features of his personality, his travel to the all cultures of the world, his relation with another character, the Turk Nasreddin Hodja, and his adaptation to the problems of the contemporary world.

  1. Australian Waste Wise Schools Program: Its Past, Present, and Future

    Science.gov (United States)

    Cutter-Mackenzie, Amy

    2010-01-01

    The Waste Wise Schools program has a longstanding history in Australia. It is an action-based program that encourages schools to move toward zero waste through their curriculum and operating practices. This article provides a review of the program, finding that it has had notable success in reducing schools' waste through a "reduce, reuse,…

  2. Slope and curvature of Isgur–Wise function using variationally ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 75; Issue 3. Slope and curvature of Isgur–Wise function using variationally improved perturbation theory in a quantum chromodynamics inspired potential model. Bhaskar Jyoti Hazarika D K Choudhury. Research Articles Volume 75 Issue 3 September 2010 pp 423- ...

  3. WISE technology: A scientific information system for astronomy and beyond

    NARCIS (Netherlands)

    Belikov, A.; Boxhoorn, D.; Begeman, K.; Valentijn, E.; Vriend, W.-j.; Williams, O. R.

    2015-01-01

    The data processing of a number of current astronomical projects require an intelligent data handling system which can satisfy the requirements both from users processing the data and users exploring the result. We present the WISE Concept of Scientific Information Systems which has been used in a

  4. Isgur–Wise function in a quantum chromodynamics-inspired ...

    Indian Academy of Sciences (India)

    We have recently reported the calculation of slope and curvature of Isgur–Wise function based on variationally improved perturbation theory (VIPT) in a quantum chromodynamics (QCD)-inspired potential model. In that work, Coulombic potential was taken as the parent while the linear one as the perturbation. In this work ...

  5. Efficiencies of MUSLE-S, MUSLT, USLE-M and AOF Models for Storm-wise Sediment Yield Estimation in Standard Plats (Case Study: Sefiddasht Research Site of Semnan

    Directory of Open Access Journals (Sweden)

    M. Kargar

    2014-12-01

    Full Text Available Soil erosion and sediment production are among most important problems in developing countries including Iran. In this study it has been endeavored that applicability of four (AOF, MUSLE-S, MUSLT and USLE-M models is investigated in Srfiddasht Research Site, Semnan province, at event scale to estimate the sediment. For this, all required variables and inputs of the model have been calculated in the watershed and the estimations from considering statistical models with measured sediments of 15 cloudbursts have been compared. The results for t-student correlation test showed that there is no significant difference (at 1% between MUSLT, MUSLE-S models and measured sediment. Based on these, it can be said that in this study, the results from these two models have higher accuracies to estimate the sediment from cloudbursts than other methods. Also, the results of evaluation and efficiency of the model using Nash-Suttcliffe criterion and root relative mean squared error (RRMSE statistic showed that MUSLE-S and MUSLT models have higher efficiencies than other models and inefficiencies of USLE-M and AOF models to estimate sediments from cloudburst have been confirmed in the studied research station in this study.

  6. On the Incidence of Wise Infrared Excess Among Solar Analog, Twin, and Sibling Stars

    Energy Technology Data Exchange (ETDEWEB)

    Da Costa, A. D.; Martins, B. L. Canto; Lima Jr, J. E.; Silva, D. Freire da; Medeiros, J. R. De [Departamento de Física Teórica e Experimental, Universidade Federal do Rio Grande do Norte, Campus Universitário, Natal, RN, 59072-970 (Brazil); Leão, I. C. [European Southern Observatory, Karl-Schwarzschild-Str. 2, D-85748 Garching (Germany); Freitas, D. B. de, E-mail: dgerson@fisica.ufrn.br [Departamento de Física, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-900, Fortaleza, Ceará (Brazil)

    2017-03-01

    This study presents a search for infrared (IR) excess in the 3.4, 4.6, 12, and 22 μ m bands in a sample of 216 targets, composed of solar sibling, twin, and analog stars observed by the Wide-field Infrared Survey Explorer ( WISE ) mission. In general, an IR excess suggests the existence of warm dust around a star. We detected 12 μ m and/or 22 μ m excesses at the 3 σ level of confidence in five solar analog stars, corresponding to a frequency of 4.1% of the entire sample of solar analogs analyzed, and in one out of 29 solar sibling candidates, confirming previous studies. The estimation of the dust properties shows that the sources with IR excesses possess circumstellar material with temperatures that, within the uncertainties, are similar to that of the material found in the asteroid belt in our solar system. No photospheric flux excess was identified at the W1 (3.4 μ m) and W2 (4.6 μ m) WISE bands, indicating that, in the majority of stars of the present sample, no detectable dust is generated. Interestingly, among the 60 solar twin stars analyzed in this work, no WISE photospheric flux excess was detected. However, a null-detection excess does not necessarily indicate the absence of dust around a star because different causes, including dynamic processes and instrument limitations, can mask its presence.

  7. On the nature and correction of the spurious S-wise spiral galaxy winding bias in Galaxy Zoo 1

    Science.gov (United States)

    Hayes, Wayne B.; Davis, Darren; Silva, Pedro

    2017-04-01

    The Galaxy Zoo 1 catalogue displays a bias towards the S-wise winding direction in spiral galaxies, which has yet to be explained. The lack of an explanation confounds our attempts to verify the Cosmological Principle, and has spurred some debate as to whether a bias exists in the real Universe. The bias manifests not only in the obvious case of trying to decide if the universe as a whole has a winding bias, but also in the more insidious case of selecting which Galaxies to include in a winding direction survey. While the former bias has been accounted for in a previous image-mirroring study, the latter has not. Furthermore, the bias has never been corrected in the GZ1 catalogue, as only a small sample of the GZ1 catalogue was reexamined during the mirror study. We show that the existing bias is a human selection effect rather than a human chirality bias. In effect, the excess S-wise votes are spuriously 'stolen' from the elliptical and edge-on-disc categories, not the Z-wise category. Thus, when selecting a set of spiral galaxies by imposing a threshold T so that max (PS, PZ) > T or PS + PZ > T, we spuriously select more S-wise than Z-wise galaxies. We show that when a provably unbiased machine selects which galaxies are spirals independent of their chirality, the S-wise surplus vanishes, even if humans still determine the chirality. Thus, when viewed across the entire GZ1 sample (and by implication, the Sloan catalogue), the winding direction of arms in spiral galaxies as viewed from Earth is consistent with the flip of a fair coin.

  8. Media coverage of "wise" interventions can reduce concern for the disadvantaged.

    Science.gov (United States)

    Ikizer, Elif G; Blanton, Hart

    2016-06-01

    Recent articulation of the "wise" approach to psychological intervention has drawn attention to the way small, seemingly trivial social psychological interventions can exert powerful, long-term effects. These interventions have been used to address such wide-ranging social issues as the racial achievement gap, environmental conservation, and the promotion of safer sex. Although there certainly are good reasons to seek easier as opposed to harder solutions to social problems, we examine a potentially undesirable effect that can result from common media portrayals of wise interventions. By emphasizing the ease with which interventions help address complex social problems, media reports might decrease sympathy for the individuals assisted by such efforts. Three studies provide evidence for this, showing that media coverage of wise interventions designed to address academic and health disparities increased endorsement of the view that the disadvantaged can solve their problems on their own, and the tendency to blame such individuals for their circumstances. Effects were strongest for interventions targeted at members of a historically disadvantaged group (African Americans as opposed to college students) and when the coverage was read by conservatives as opposed to liberals. Attempts to undermine this effect by introducing cautious language had mixed success. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  9. The WISE Survey of the Albedo Distribution of Main Belt Asteroids

    NARCIS (Netherlands)

    Masiero, J.; Mainzer, A.; Grav, T.; Delbó, M.; Mueller, M.; WISE Team, [No Value

    2010-01-01

    Using date from the Wide-field Infrared Survey Explorer (WISE) we investigate the albedo distribution across the main belt of asteroids. When complete WISE will measure albedos and diameters for ~100,000 asteroids.

  10. Protocol for a cluster randomised controlled trial of an intervention to improve the mental health support and training available to secondary school teachers – the WISE (Wellbeing in Secondary Education study

    Directory of Open Access Journals (Sweden)

    Judi Kidger

    2016-10-01

    Full Text Available Abstract Background Teachers are reported to be at increased risk of common mental health disorders compared to other occupations. Failure to support teachers adequately may lead to serious long-term mental disorders, poor performance at work (presenteeism, sickness absence and health-related exit from the profession. It also jeopardises student mental health, as distressed staff struggle to develop supportive relationships with students, and such relationships are protective against student depression. A number of school-based trials have attempted to improve student mental health, but these have mostly focused on classroom based approaches and have failed to establish effectiveness. Only a few studies have introduced training for teachers in supporting students, and none to date have included a focus on improving teacher mental health. This paper sets out the protocol (version 4.4 20/07/16 for a study aiming to address this gap. Methods Cluster randomised controlled trial with secondary schools as the unit of randomisation. Intervention schools will receive: i Mental Health First Aid (MHFA training for a group of staff nominated by their colleagues, after which they will set up a confidential peer support service for colleagues ii training in MHFA for schools and colleges for a further group of teachers, which will equip them to more effectively support student mental health iii a short mental health awareness raising session and promotion of the peer support service for all teachers. Comparison schools will continue with usual practice. The primary outcome is teacher wellbeing measured using the Warwick Edinburgh Mental Wellbeing Scale (WEMWBS. Secondary outcomes are teacher depression, absence and presenteeism, and student wellbeing, mental health difficulties, attendance and attainment. Measures will be taken at baseline, one year follow up (teachers only and two year follow up. Economic and process evaluations will be embedded within the

  11. Protocol for a cluster randomised controlled trial of an intervention to improve the mental health support and training available to secondary school teachers - the WISE (Wellbeing in Secondary Education) study.

    Science.gov (United States)

    Kidger, Judi; Evans, Rhiannon; Tilling, Kate; Hollingworth, William; Campbell, Rona; Ford, Tamsin; Murphy, Simon; Araya, Ricardo; Morris, Richard; Kadir, Bryar; Moure Fernandez, Aida; Bell, Sarah; Harding, Sarah; Brockman, Rowan; Grey, Jill; Gunnell, David

    2016-10-18

    Teachers are reported to be at increased risk of common mental health disorders compared to other occupations. Failure to support teachers adequately may lead to serious long-term mental disorders, poor performance at work (presenteeism), sickness absence and health-related exit from the profession. It also jeopardises student mental health, as distressed staff struggle to develop supportive relationships with students, and such relationships are protective against student depression. A number of school-based trials have attempted to improve student mental health, but these have mostly focused on classroom based approaches and have failed to establish effectiveness. Only a few studies have introduced training for teachers in supporting students, and none to date have included a focus on improving teacher mental health. This paper sets out the protocol (version 4.4 20/07/16) for a study aiming to address this gap. Cluster randomised controlled trial with secondary schools as the unit of randomisation. Intervention schools will receive: i) Mental Health First Aid (MHFA) training for a group of staff nominated by their colleagues, after which they will set up a confidential peer support service for colleagues ii) training in MHFA for schools and colleges for a further group of teachers, which will equip them to more effectively support student mental health iii) a short mental health awareness raising session and promotion of the peer support service for all teachers. Comparison schools will continue with usual practice. The primary outcome is teacher wellbeing measured using the Warwick Edinburgh Mental Wellbeing Scale (WEMWBS). Secondary outcomes are teacher depression, absence and presenteeism, and student wellbeing, mental health difficulties, attendance and attainment. Measures will be taken at baseline, one year follow up (teachers only) and two year follow up. Economic and process evaluations will be embedded within the study. This study will establish the

  12. AGE WISE HISTOMORPHOLOGICAL CHANGES IN HUMAN LIVER

    Directory of Open Access Journals (Sweden)

    Tribeni

    2015-11-01

    Full Text Available CONTEXT: Hepato cellular carcinoma (HCC results in between 2.5 lakhs to 1million deaths globally per annum. Liver transplantation nowadays is a well accepted treatment option for end-stage liver disease and acute liver failure. AIMS: Keeping this concept in view, a study was conducted in the Guwahati Zone of Northeast India, to compare the histomorphological features of the human liver in different age groups. SETTING AND DESIGN: Apparently healthy livers were obtained from 21 subjects on whom medicolegal post-mortems had been performed. Their ages varied from newborn to 90 years. Subjects were divided into 3 groups. 7 specimens were taken from each group. (1 Pediatric (2 Adult (3 Old age. METHODS AND MATERIALS: In all the above age groups, immediately after removal of the livers, they were washed in normal saline, dried with blotting paper and weighed in an electronic weighing machine. Sections of liver were fixed, processed, cut and stained with Harris Haematoxylin and Eosin stain. RESULTS: The liver loses weight from 50 years onwards. There appears to be racial and environmental differences in the change in liver weight in old age. Autopsy studies show a diminution of nearly 46% in liver weight between the 3rd and 10th decades of life. The liver decreases in size with age. The hepatocytes are radially disposed in the liver lobule. They are piled up, forming a layer one cell thick (except in young children in a fashion similar to the bricks of a wall. These plates are directed from the periphery of the lobule to its centre and anastomose freely forming a complex labyrinthine and sponge-like structure. CONCLUSIONS: From the findings in the present study it can be concluded that: 1. Nowadays, the measurement of liver volume has gained practical use in relation to liver transplantation. 2. We have compared the histomorphology of adult liver with a child. The findings in both the groups are very similar. This feature is important, since in

  13. Melanin fluorescence spectra by step-wise three photon excitation

    Science.gov (United States)

    Lai, Zhenhua; Kerimo, Josef; DiMarzio, Charles A.

    2012-03-01

    Melanin is the characteristic chromophore of human skin with various potential biological functions. Kerimo discovered enhanced melanin fluorescence by stepwise three-photon excitation in 2011. In this article, step-wise three-photon excited fluorescence (STPEF) spectrum between 450 nm -700 nm of melanin is reported. The melanin STPEF spectrum exhibited an exponential increase with wavelength. However, there was a probability of about 33% that another kind of step-wise multi-photon excited fluorescence (SMPEF) that peaks at 525 nm, shown by previous research, could also be generated using the same process. Using an excitation source at 920 nm as opposed to 830 nm increased the potential for generating SMPEF peaks at 525 nm. The SMPEF spectrum peaks at 525 nm photo-bleached faster than STPEF spectrum.

  14. Space-Wise approach for airborne gravity data modelling

    Science.gov (United States)

    Sampietro, D.; Capponi, M.; Mansi, A. H.; Gatti, A.; Marchetti, P.; Sansò, F.

    2017-05-01

    Regional gravity field modelling by means of remove-compute-restore procedure is nowadays widely applied in different contexts: it is the most used technique for regional gravimetric geoid determination, and it is also used in exploration geophysics to predict grids of gravity anomalies (Bouguer, free-air, isostatic, etc.), which are useful to understand and map geological structures in a specific region. Considering this last application, due to the required accuracy and resolution, airborne gravity observations are usually adopted. However, due to the relatively high acquisition velocity, presence of atmospheric turbulence, aircraft vibration, instrumental drift, etc., airborne data are usually contaminated by a very high observation error. For this reason, a proper procedure to filter the raw observations in both the low and high frequencies should be applied to recover valuable information. In this work, a software to filter and grid raw airborne observations is presented: the proposed solution consists in a combination of an along-track Wiener filter and a classical Least Squares Collocation technique. Basically, the proposed procedure is an adaptation to airborne gravimetry of the Space-Wise approach, developed by Politecnico di Milano to process data coming from the ESA satellite mission GOCE. Among the main differences with respect to the satellite application of this approach, there is the fact that, while in processing GOCE data the stochastic characteristics of the observation error can be considered a-priori well known, in airborne gravimetry, due to the complex environment in which the observations are acquired, these characteristics are unknown and should be retrieved from the dataset itself. The presented solution is suited for airborne data analysis in order to be able to quickly filter and grid gravity observations in an easy way. Some innovative theoretical aspects focusing in particular on the theoretical covariance modelling are presented too

  15. Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions

    DEFF Research Database (Denmark)

    Bøtker, Johan P; Karmwar, Pranav; Strachan, Clare J

    2011-01-01

    The aim of this study was to investigate the usefulness of the atomic pair-wise distribution function (PDF) to detect the extension of disorder/amorphousness induced into a crystalline drug using a cryo-milling technique, and to determine the optimal milling times to achieve amorphisation. The PDF...

  16. Exploring the Universe with WISE and Cloud Computing

    Science.gov (United States)

    Benford, Dominic J.

    2011-01-01

    WISE is a recently-completed astronomical survey mission that has imaged the entire sky in four infrared wavelength bands. The large quantity of science images returned consists of 2,776,922 individual snapshots in various locations in each band which, along with ancillary data, totals around 110TB of raw, uncompressed data. Making the most use of this data requires advanced computing resources. I will discuss some initial attempts in the use of cloud computing to make this large problem tractable.

  17. Pixel-wise Segmentation of Street with Neural Networks

    OpenAIRE

    Bittel, Sebastian; Kaiser, Vitali; Teichmann, Marvin; Thoma, Martin

    2015-01-01

    Pixel-wise street segmentation of photographs taken from a drivers perspective is important for self-driving cars and can also support other object recognition tasks. A framework called SST was developed to examine the accuracy and execution time of different neural networks. The best neural network achieved an $F_1$-score of 89.5% with a simple feedforward neural network which trained to solve a regression task.

  18. Psychometric properties of the Spanish version of the Body Weight, Image and Self-Esteem Evaluation Questionnaire in patients with severe mental disorders.

    Science.gov (United States)

    Al-Halabi, Susana; Garcia-Portilla, Maria Paz; Saiz, Pilar Alejandra; Fonseca, Eduardo; Bobes-Bascaran, Maria Teresa; Galván, Gonzalo; Iglesias, Celso; Arrojo, Manuel; Benabarre, Antoni; Goikolea, José Manuel; Sanchez, Emilio; Sarramea, Fernando; Bobes, Julio

    2012-11-01

    Clinicians need brief and valid instruments to monitor the psychosocial impact of weight gain in persons with psychiatric disorders. We examined the psychometric properties of the Spanish version of the Body Weight, Image and Self-Esteem Evaluation (B-WISE) questionnaire in patients with severe mental disorders. The data come from a naturalistic, cross-sectional, validation study conducted at 6 centres in Spain. A total of 211 outpatients with severe mental disorders, 118 with schizophrenia and 93 with bipolar disorder, were evaluated using the B-WISE, the Visual Analogue Scale for Weight and Body Image, and the Clinical Global Impression-Severity (CGI-S). The body mass index was also obtained. The principal component analysis confirms 3 components explaining 50.93% of the variance. The Cronbach α values for B-WISE scales ranged between .55 and .73. Significant Pearson correlations were found between B-WISE total score and CGI-S (r = -0.25; P Body Image (r = 0.47; P Body mass index categorization significantly influenced total B-WISE scores (F = 3.586, P < .050). The B-WISE score corresponding to the 5th and 10th percentiles was 22. We were able to demonstrate that the Spanish version of the B-WISE is a valid instrument for assessing psychosocial impact of weight gain in patients with severe mental disorders in daily clinical practice. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.

    Science.gov (United States)

    Ahn, Youngwook; Sims, Carrie; Logue, Jennifer M; Weatherbee, Scott D; Krumlauf, Robb

    2013-02-01

    The future site of skin appendage development is marked by a placode during embryogenesis. Although Wnt/β-catenin signaling is known to be essential for skin appendage development, it is unclear which cellular processes are controlled by the signaling and how the precise level of the signaling activity is achieved during placode formation. We have investigated roles for Lrp4 and its potential ligand Wise (Sostdc1) in mammary and other skin appendage placodes. Lrp4 mutant mice displayed a delay in placode initiation and changes in distribution and number of mammary precursor cells leading to abnormal morphology, number and position of mammary placodes. These Lrp4 mammary defects, as well as limb defects, were associated with elevated Wnt/β-catenin signaling and were rescued by reducing the dose of the Wnt co-receptor genes Lrp5 and Lrp6, or by inactivating the gene encoding β-catenin. Wise-null mice phenocopied a subset of the Lrp4 mammary defects and Wise overexpression reduced the number of mammary precursor cells. Genetic epistasis analyses suggest that Wise requires Lrp4 to exert its function and that, together, they have a role in limiting mammary fate, but Lrp4 has an early Wise-independent role in facilitating placode formation. Lrp4 and Wise mutants also share defects in vibrissa and hair follicle development, suggesting that the roles played by Lrp4 and Wise are common to skin appendages. Our study presents genetic evidence for interplay between Lrp4 and Wise in inhibiting Wnt/β-catenin signaling and provides an insight into how modulation of Wnt/β-catenin signaling controls cellular processes important for skin placode formation.

  20. Flap-wise and chord-wise vibrations of axially functionally graded tapered beams rotating around a hub

    Science.gov (United States)

    Mazanoglu, Kemal; Guler, Serkan

    2017-05-01

    This paper presents flap-wise and chord-wise flexural vibration analyses for centrifugally stiffened tapered beams made of functionally graded material in axial direction. Functions of material properties varying along beam are defined in terms of the power law distribution. Calculations are conducted by simple computation technique of the Rayleigh-Ritz method that uses simple shape functions and energy expressions written for centrifugally stiffened Euler-Bernoulli beams. Effects of taper ratio, hub radius, angular velocity and non-homogeneity are inspected for the thin beams with several classical boundary conditions. Results given as non-dimensional natural frequencies are validated by the results given in existing literature and/or the outputs of finite element analyses performed for axially functionally graded solid beam. Achievements and limitations of the method are discussed and clearly reflected.

  1. Conversion of failed vertical banded gastroplasty to biliopancreatic diversion, a wise option.

    Science.gov (United States)

    Daskalakis, Markos; Scheffel, Oliver; Theodoridou, Sophia; Weiner, Rudolf A

    2009-12-01

    Reoperations due to failures constitute an essential but challenging part of bariatric surgery practice today. The aim of this study was to evaluate the perioperative safety, efficacy, and postoperative quality of life in patients with biliopancreatic diversion (BPD), after failed vertical banded gastroplasty (VBG). Twelve patients after failed or complicated VBG, eight females and four males, median age 45 years (range 39-52), median body mass index (BMI) 46.39 kg/m2 (range 25.89-69.37), who underwent conversion to BPD, were studied. Ten patients due to weight regain and two patients because of severe stenosis of the gastric pouch outlet were submitted in conversion to BPD. In eight (66.6%) patients the primary VBG had been followed by at least one revisional operation due to inadequate weight loss. The 10 patients after failed VBG, reached the lowest BMI recorded after VBG in just a year after BPD (p=0.721 for the comparison between the two time points). The two patients with stomal stenosis regained weight in the first six postoperative months and remain stable since then. Regarding safety, one major perioperative complication (gastrojejunostomy stenosis) occurred. At a median follow-up of 21 months (range 12-30) six complications have been documented, including a case of incisional hernia, four cases of pouch gastritis and a case of intractable iron-deficiency anemia. Our early results indicate that conversion of failed VBG to BPD is highly effective with acceptable morbidity. Our data show that the effect on weight is strongly dependent on the indication for the conversion. Conversion to BPD, in such a group of patients, is a wise alternative, since it may reduce operative risks.

  2. Unveiling hidden black holes in the cosmic web: Dark matter halos of WISE quasars from Planck CMB lensing

    Science.gov (United States)

    Hickox, Ryan

    The WISE and Planck surveys have now produced groundbreaking data sets which, in concert, can be exploited to obtain revolutionary constraints on the evolution of structure in the Universe. One particularly powerful application of WISE has been to uncover millions of the previously "hidden" obscured quasars, rapidly growing supermassive black holes that are shrouded in gas and dust and so are not detectable using traditional ground-based optical and near-IR techniques. Recently, Planck has produced the most precise all-sky map to date of dark matter structures via the lensing of the cosmic microwave background (CMB). We propose to combine these data sets to obtain a uniquely powerful measurement of the link between rapidly growing black holes and their host dark matter structures, by cross-correlating the density field of WISE-selected quasars with the CMB lensing convergence maps obtained from Planck. This proposal will build on our current ADAP program (NNX12AE38G), which studies the host dark matter halos of WISE-selected quasars via spatial clustering. NNX12AE38G involves a detailed characterization of the redshifts, luminosities, and spectral energy distributions of WISE-selected quasars and uses new techniques to measure how quasars cluster around themselves. NNX12AE38G has contributed to more than 10 journal articles and 5 conference proceedings. Building on our current work, an even more complete understanding of the link between black holes and their host dark matter structures is possible if we employ an independent method for measuring the clustering bias (and thus characteristic halo mass) of the quasar population. This has recently become possible using CMB lensing maps. In the past two years, our team has conducted an initial analysis covering 2500 square degrees using WISE-selected quasars and lensing maps from the South Pole Telescope (Geach, Hickox, Myers et al., 2013), and have implemented this technique with Planck over part of the SDSS region

  3. Effectiveness of WISE colour-based selection techniques to uncover obscured AGN

    OpenAIRE

    Mateos, S.

    2014-01-01

    We present a highly reliable and efficient mid-infrared colour-based selection technique for luminous active galactic nuclei (AGN) using the Wide-field Infrared Survey Explorer (WISE) survey. Our technique is designed to identify objects with red mid-infrared power-law spectral energy distributions. We studied the dependency of our mid-infrared selection on the AGN intrinsic luminosity and the effectiveness of our technique to uncover obscured AGN missed in X-ray surveys. To do so we used two...

  4. VizieR Online Data Catalog: HCG and RSCG compact group galaxies with WISE (Zucker+, 2016)

    Science.gov (United States)

    Zucker, C.; Walker, L. M.; Johnson, K.; Gallagher, S.; Alatalo, K.; Tzanavaris, P.

    2016-07-01

    For this study, we draw our sample from groups in the HCG catalog (Hickson 1982, VII/213) and the Redshift Survey Compact Group catalog (RSCG; Barton et al. 1996AJ....112..871B). We utilize new ALLWISE coadds from Lang (unWISE; 2014AJ....147..108L), which preserve the native resolution of the raw frames (~6.1", 6.4", 6.5" and 12.0" for bands W1, W2, W3, and W4). (1 data file).

  5. WISE: a content-based Web image search engine

    Science.gov (United States)

    Qiu, Guoping; Palmer, R. D.

    2000-12-01

    This paper describes the development of a prototype of a Web Image Search Engine (WISE), which allows users to search for images on the WWW by image examples, in a similar fashion to current search engines that allow users to find related Web pages using text matching on keywords. The system takes an image specified by the user and finds similar images available on the WWW by comparing the image contents using low level image features. The current version of the WISE system consists of a graphical user interface (GUI), an autonomous Web agent, an image comparison program and a query processing program. The users specify the URL of a target image and the URL of the starting Web page from where the program will 'crawl' the Web, finding images along the way and retrieve those satisfying a certain constraints. The program then computes the visual features of the retrieved images and performs content-based comparison with the target image. The results of the comparison are then sorted according to a certain similarity measure, which along with thumbnails and information associated with the images, such as the URLs; image size, etc. are then written to an HTML page. The resultant page is stored on a Web server and is outputted onto the user's Web browser once the search process is complete. A unique feature of the current version of WISE is its image content comparison algorithm. It is based on the comparison of image palettes and it therefore very efficient in retrieving one of the two universally accepted image formats on the Web, 'gif.' In gif images, the color palette is contained in its header and therefore it is only necessary to retrieve the header information rather than the whole images, thus making it very efficient.

  6. SUBMILLIMETER FOLLOW-UP OF WISE-SELECTED HYPERLUMINOUS GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Wu Jingwen; Eisenhardt, Peter R. M.; Stern, Daniel; Assef, Roberto [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States); Tsai, Chao-Wei; Cutri, Roc; Griffith, Roger; Jarrett, Thomas [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Sayers, Jack; Bridge, Carrie [Division of Physics, Math and Astronomy, California Institute of Technology, Pasadena, CA 91125 (United States); Benford, Dominic [NASA Goddard Space Flight Center, Greenbelt, MD 20771 (United States); Blain, Andrew [Department of Physics and Astronomy, University of Leicester, LE1 7RH Leicester (United Kingdom); Petty, Sara; Lake, Sean [Department of Physics and Astronomy, University of California Los Angeles, Los Angeles, CA 90095 (United States); Bussmann, Shane [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, MS78, Cambridge, MA 02138 (United States); Comerford, Julia M.; Evans, Neal J. II [Department of Astronomy, University of Texas, Austin, TX 78731 (United States); Lonsdale, Carol [National Radio Astronomy Observatory, 520 Edgemont Road, Charlottesville, VA 22903 (United States); Rho, Jeonghee [SETI Institute, 189 BERNARDO Avenue, Mountain View, CA 94043 (United States); Stanford, S. Adam, E-mail: jingwen.wu@jpl.nasa.gov [Department of Physics, University of California Davis, One Shields Avenue, Davis, CA 95616 (United States); and others

    2012-09-01

    We have used the Caltech Submillimeter Observatory (CSO) to follow-up a sample of Wide-field Infrared Survey Explorer (WISE) selected, hyperluminous galaxies, the so-called W1W2-dropout galaxies. This is a rare ({approx}1000 all-sky) population of galaxies at high redshift (peaks at z = 2-3), which are faint or undetected by WISE at 3.4 and 4.6 {mu}m, yet are clearly detected at 12 and 22 {mu}m. The optical spectra of most of these galaxies show significant active galactic nucleus activity. We observed 14 high-redshift (z > 1.7) W1W2-dropout galaxies with SHARC-II at 350-850 {mu}m, with nine detections, and observed 18 with Bolocam at 1.1 mm, with five detections. Warm Spitzer follow-up of 25 targets at 3.6 and 4.5 {mu}m, as well as optical spectra of 12 targets, are also presented in the paper. Combining WISE data with observations from warm Spitzer and CSO, we constructed their mid-IR to millimeter spectral energy distributions (SEDs). These SEDs have a consistent shape, showing significantly higher mid-IR to submillimeter ratios than other galaxy templates, suggesting a hotter dust temperature. We estimate their dust temperatures to be 60-120 K using a single-temperature model. Their infrared luminosities are well over 10{sup 13} L{sub Sun }. These SEDs are not well fitted with existing galaxy templates, suggesting they are a new population with very high luminosity and hot dust. They are likely among the most luminous galaxies in the universe. We argue that they are extreme cases of luminous, hot dust-obscured galaxies (DOGs), possibly representing a short evolutionary phase during galaxy merging and evolution. A better understanding of their long-wavelength properties needs ALMA as well as Herschel data.

  7. WISE/NEOWISE Observations of the Hilda Population: Preliminary Results

    OpenAIRE

    Grav, T.; Mainzer, A. K.; Bauer, J.; Masiero, J.; Spahr, T.; McMillan, R. S.; Walker, R; Cutri, R.; Wright, E.; Eisenhardt, P. R.; Blauvelt, E.; DeBaun, E.; Elsbury, D; Gautier IV, T.; Gomillion, S.

    2012-01-01

    We present the preliminary analysis of 1023 known asteroids in the Hilda region of the Solar System observed by the NEOWISE component of the Wide-field Infrared Survey Explorer (WISE). The sizes of the Hildas observed range from $\\sim 3 - 200$km. We find no size - albedo dependency as reported by other projects. The albedos of our sample are low, with a weighted mean value $p_V = 0.055\\pm0.018$, for all sizes sampled by the NEOWISE survey. We observed a significant fraction of the objects in ...

  8. Report of the Wises Committee; Rapport du Comite des Sages

    Energy Technology Data Exchange (ETDEWEB)

    Castillon, P.; Lesggy, M.; Morin, E.

    2003-09-01

    This report on the energy theme, calls in experts in different areas such economics, technologies, regulations, fiscality, geopolitics, regional, european and international approaches. Because of numerous constraints, interactions in the energy subject, the Wises Committee has wished to tackle in priority the subject under a point of view less technical, by insisting on the necessary sudden awareness of the public about stakes in the energy field, on the necessity to implement actions for energy efficiency without waiting for the crisis situations that will come from excess of energy consumption. (N.C.)

  9. NORTHERN OHIO AEROSOL STUDY: STAPHYLOCOCCUS AUREUS EVALUATION

    Science.gov (United States)

    A consortium of Universities, located in northwest Ohio have received funds to conduct a comprehensive evaluation of land applied biosolids in that state. This USDA funded study includes observing land application practices and evaluating biosolids, soils, runoff water and bioaer...

  10. Crescent Evaluation : appendix B : state case study evaluation report

    Science.gov (United States)

    1994-02-01

    The state case study evaluation approach uniquely captured an understanding of the potential of such a system by documenting the experiences, issues, and opportunities of selected key state government personnel from a cross-section of involved agenci...

  11. Can local voluntary environmental programs "work"? An examination of Fort Collins' (Colorado) climate wise program.

    Science.gov (United States)

    Mosier, Samantha; Samantha, Mosier; Fisk, Jonathan; Jonathan, Fisk

    2013-05-01

    Previous research on voluntary environmental programs (VEPs) frequently assesses the effectiveness of federal, state, and third party programs and why organizations seek to join such programs. Yet, research has yet to evaluate the effectiveness or firm motivation relative to local VEPs. Recognizing this gap, our paper examines the structure and organization of Fort Collins' Climate Wise program, a local VEP. Using a variety of sources, we find that the program has successfully met both short- and long-term goals by persistently self-evaluating and seeking outside financial support. Findings from this analysis can aid in understanding and developing local VEPs elsewhere. Specifically, this initial research suggests that local VEPs need to consider local context and available resources when implementing such programs. Furthermore, it is possible for local VEPs to attract a diverse variety of participating firms by avoiding one-size-fits-all participation levels and by establishing a sense of ownership among partners.

  12. Can Local Voluntary Environmental Programs "Work"? An Examination of Fort Collins' (Colorado) Climate Wise Program

    Science.gov (United States)

    Samantha, Mosier; Jonathan, Fisk

    2013-05-01

    Previous research on voluntary environmental programs (VEPs) frequently assesses the effectiveness of federal, state, and third party programs and why organizations seek to join such programs. Yet, research has yet to evaluate the effectiveness or firm motivation relative to local VEPs. Recognizing this gap, our paper examines the structure and organization of Fort Collins' Climate Wise program, a local VEP. Using a variety of sources, we find that the program has successfully met both short- and long-term goals by persistently self-evaluating and seeking outside financial support. Findings from this analysis can aid in understanding and developing local VEPs elsewhere. Specifically, this initial research suggests that local VEPs need to consider local context and available resources when implementing such programs. Furthermore, it is possible for local VEPs to attract a diverse variety of participating firms by avoiding one-size-fits-all participation levels and by establishing a sense of ownership among partners.

  13. [New "choosing wisely" recommendations of inappropriate interventions: the perspective of general practioners in Switzerland].

    Science.gov (United States)

    Neuner-Jehle, Stefan; Senn, Oliver; Rosemann, Thomas

    2016-12-01

    As part of the "Choosing wisely" campaign expert-driven recommendations of inappropriate interventions which lead to overdiagnosis and overtreatment are being published. The aim of our work was to describe an innovative method for developing recommendations together with general practitioners (GPs) and to compare the results with the "Choosing wisely" campaign lists as well as with the Swiss "Smarter medicine" shortlist. We asked 109 GPs who attended a medical education conference to form groups (of 5 to 7 GPs each) and develop three interventions that are relevant to their work and should be avoided. We then compared the most frequently suggested interventions with those of the "Choosing wisely" campaign list and the "Smarter medicine" campaign shortlist. Finally, we asked the Swiss Young GPs Association (JHaS) members for additional suggestions. Five groups suggested avoidance of check-up examinations, especially in younger or asymptomatic individuals. Further unnecessary interventions, which were mentioned with similar frequency, included resting or exercise electrocardiography in asymptomatic individuals and cholesterol analysis in individuals older than 75 years, or statin therapy in primary prevention and/or high age. Four groups suggested avoiding arthroscopy or magnetic resonance imaging of the knee joint after an injury (in the absence of joint instability or blockade), and three groups recommended to avoid imaging diagnostic procedures in patients with unspecific headache (in the absence of red flags). There was no consistency between interventions of the GPs' list and the list of the Swiss "Smarter medicine" official campaign. The interventions that were most frequently mentioned by the GPs are also present on the lists issued by are present on lists of medical societies that have joined the "Choosing wisely" campaign. The response rate from the Swiss Young GPs association members was impressively low. The perspective of users (GPs) is crucial for the

  14. Relationships between HI Gas Mass, Stellar Mass and Star Formation Rate of HICAT+WISE Galaxies

    Science.gov (United States)

    Parkash, Vaishali; Brown, Michael J. I.

    2018-01-01

    Galaxies grow via a combination of star formation and mergers. In this thesis, I have studied what drives star formation in nearby galaxies. Using archival WISE, Galex, 21-cm data and new IFU observations, I examine the HI content, Hα emission, stellar kinematics, and gas kinematics of three sub-classes of galaxies: spiral galaxies, shell galaxies and HI galaxies with unusually low star formation rates (SFR). In this dissertation talk, I will focus on the scaling relations between atomic (HI) gas, stellar mass and SFR of spiral galaxies. Star formation is fuelled by HI and molecular hydrogen, therefore we expect correlations between HI mass, stellar mass and SFR. However, the measured scaling relationships vary in the prior literature due to sample selection or low completeness. I will discuss new scaling relationships determined using HI Parkes All Sky-Survey Catalogue (HICAT) and the Wide-field Infrared Survey Explorer (WISE). The combination of the local HICAT survey with sensitive WISE mid-infrared imaging improves the stellar masses, SFRs and completeness relative to previous literature. Of the 3,513 HICAT sources, we find 3.4 μm counterparts for 2,824 sources (80%), and provide new WISE matched aperture photometry for these galaxies. For a stellar mass selected sample of z ≤ 0.01 spiral galaxies, we find HI detections for 94% of the galaxies, enabling us to accurately measure HI mass as a function of stellar mass. In contrast to HI-selected galaxy samples, we find that star formation efficiency of spiral galaxies is constant at 10-9.5 yr‑1 with a scatter of 0.5 dex for stellar masses above 109.5 solar masses. We find HI mass increases with stellar mass for spiral galaxies, but the scatter is 1.7 dex for all spiral galaxies and 0.6 dex for galaxies with the T-type 5 to 7. We find an upper limit on HI mass that depends on stellar mass, which is consistent with this limit being dictated by the halo spin parameter.

  15. WISE/NEOWISE OBSERVATIONS OF THE HILDA POPULATION: PRELIMINARY RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Grav, T. [Department of Physics and Astronomy, Johns Hopkins University, Baltimore, MD 21218 (United States); Mainzer, A. K.; Bauer, J.; Masiero, J.; Eisenhardt, P. R.; Blauvelt, E.; DeBaun, E.; Elsbury, D.; Gautier, T.; Gomillion, S.; Hand, E.; Wilkins, A. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Spahr, T. [Minor Planet Center, Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); McMillan, R. S. [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721 (United States); Walker, R. [Monterey Institute for Research in Astronomy, Marina, CA 93933 (United States); Cutri, R. [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Wright, E., E-mail: tgrav@pha.jhu.edu [UCLA Astronomy, Los Angles, CA 90095 (United States)

    2012-01-10

    We present the preliminary analysis of 1023 known asteroids in the Hilda region of the solar system observed by the NEOWISE component of the Wide-field Infrared Survey Explorer (WISE). The sizes of the Hildas observed range from {approx}3 to 200 km. We find no size-albedo dependency as reported by other projects. The albedos of our sample are low, with a weighted mean value of p{sub V} = 0.055 {+-} 0.018, for all sizes sampled by the NEOWISE survey. We observed a significant fraction of the objects in the two known collisional families in the Hilda population. It is found that the Hilda collisional family is brighter, with a weighted mean albedo of p{sub V} = 0.061 {+-} 0.011, than the general population and dominated by D-type asteroids, while the Schubart collisional family is darker, with a weighted mean albedo of p{sub V} = 0.039 {+-} 0.013. Using the reflected sunlight in the two shortest WISE bandpasses, we are able to derive a method for taxonomic classification of {approx}10% of the Hildas detected in the NEOWISE survey. For the Hildas with diameter larger than 30 km, there are 67{sup +7}{sub -15}% D-type asteroids and 26{sup +17}{sub -5%} C-/P-type asteroids (with the majority of these being P-types).

  16. A WISE survey of circumstellar disks in Taurus

    Energy Technology Data Exchange (ETDEWEB)

    Esplin, T. L.; Luhman, K. L. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Mamajek, E. E., E-mail: taran.esplin@psu.edu [Department of Physics and Astronomy, The University of Rochester, Rochester, NY 14627 (United States)

    2014-04-01

    We have compiled photometry at 3.4, 4.6, 12, and 22 μm from the all-sky survey performed by the Wide-field Infrared Survey Explorer (WISE) for all known members of the Taurus complex of dark clouds. Using these data and photometry from the Spitzer Space Telescope, we have identified members with infrared excess emission from circumstellar disks and have estimated the evolutionary stages of the detected disks, which include 31 new full disks and 16 new candidate transitional, evolved, evolved transitional, and debris disks. We have also used the WISE All-Sky Source Catalog to search for new disk-bearing members of Taurus based on their red infrared colors. Through optical and near-infrared spectroscopy, we have confirmed 26 new members with spectral types of M1-M7. The census of disk-bearing stars in Taurus should now be largely complete for spectral types earlier than ∼M8 (M ≳ 0.03 M {sub ☉}).

  17. FEATURE EVALUATION FOR BUILDING FACADE IMAGES – AN EMPIRICAL STUDY

    Directory of Open Access Journals (Sweden)

    M. Y. Yang

    2012-08-01

    Full Text Available The classification of building facade images is a challenging problem that receives a great deal of attention in the photogrammetry community. Image classification is critically dependent on the features. In this paper, we perform an empirical feature evaluation task for building facade images. Feature sets we choose are basic features, color features, histogram features, Peucker features, texture features, and SIFT features. We present an approach for region-wise labeling using an efficient randomized decision forest classifier and local features. We conduct our experiments with building facade image classification on the eTRIMS dataset, where our focus is the object classes building, car, door, pavement, road, sky, vegetation, and window.

  18. A WISE Survey of Star Formation in the Milky Way: New Insight into Galaxy Evolution

    Science.gov (United States)

    Koenig, Xavier

    We propose to measure the recent star formation rate (SFR) in the Perseus Arm of the Milky Way galaxy and its relation to the surface density of gas, whether molecular or atomic on a range of scales from star forming clusters through large star forming complexes to the full scale of the Galactic Arm. We will test the connection between the SFR-gas relationship in the Galaxy and comparable measurements made in external galaxies in order to probe its origin and better understand the role and contribution of star formation to cosmological galaxy evolution. We also propose to study star formation that has been triggered by the recent formation of massive star clusters in order to discern the mechanisms of triggering that may be operating on super bubble size scales of more than 100 parsecs. This study will allow us to understand one of the key factors that sets the efficiency with which gas becomes stars as galaxies evolve with time. In order to achieve these goals, we will carry out a census of young stellar objects in the outer Milky Way Perseus Arm, using data gathered by the WISE and 2MASS all-sky surveys, with additional use of archival data from the Spitzer Space Telescope. We will develop and refine a young star finding algorithm that uses WISE and 2MASS photometry to identify and classify young stars and filters out contaminating objects such as background galaxies. We will measure the gas content with extinction maps made with data from 2MASS. We will test the triggered star formation models by analyzing the spatial distributions of young stars in super-bubbles and massive star forming regions in the Perseus Arm. This study will produce a key, like-for-like comparison between the extragalactic star formation rate-molecular gas relation and the Galactic relation and will advance the progress in linking Galactic and extragalactic studies of star formation, studying massive star forming regions that are representative of the major mode of star formation. The

  19. Case study: lessons from a laryngeal abscess | Wise | Southern ...

    African Journals Online (AJOL)

    This case report focuses on a patient who presented with respiratory distress and with a background history of asthma. The underlying pathology is explored, as well as the diagnostic error that could have resulted in serious complications. Keywords: asthma, error, laryngeal abscess, squamous carcinoma ...

  20. Case study: lessons from a laryngeal abscess | Wise | Southern ...

    African Journals Online (AJOL)

    Southern African Journal of Anaesthesia and Analgesia. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 21, No 4 (2015) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Download this PDF file. The PDF file you selected ...

  1. Experimental investigation of a large aspect ratio flat plate encountering a steam-wise gust

    Science.gov (United States)

    Mulleners, Karen; Mancini, Peter; Jones, Anya

    2015-11-01

    While humans are capable of mimicking, and even outperform, the kinematic capabilities of natural flyers, birds and insects are still way ahead of us when it comes to anticipating and dealing with turbulent and gusty flow conditions. To tailor and improve flight control capabilities of low Reynolds number flyers in real weather, we need to bridge this gap of knowledge. As a first step, we experimentally studied the aerodynamic influence of a simplified stream-wise gust on a large aspect ratio flat plate. The experiments were conduction in the 7 × 1 . 5 × 1 m3 towing tank at UMD which was equipped with a 4-axis computer-controlled motion system. The effect of a stream-wise gust was simulated by accelerating or decelerating the wing to a new constant velocity after an initial constant surge. A high-speed camera and light sheet optics were attached to the tow carriage allowing for time-resolved particle image velocimetry along the entire motion in addition to direct force measurements. A proper orthogonal decomposition of the flow field was carried out to study the time scales related to changes induced by the sudden acceleration or deceleration in addition to analyzing the size, position and trajectory of prominent vortices and associated forces during the gust encounter.

  2. Study design considerations in evaluating environmental impacts

    Science.gov (United States)

    Stan T. Lebow; Paul A. Cooper; Patricia Lebow

    2006-01-01

    The purpose of this chapter is to make the reader aware of how choices in study parameters may influence the outcome of treated-wood environmental impact evaluations. Evaluation of the leaching and environmental accumulation of preservatives from treated wood is a complex process. and many factors can influence the results of such studies. In laboratory studies, the...

  3. Low complexity symbol-wise beamforming for MIMO-OFDM systems

    KAUST Repository

    Lee, Hyun Ho

    2011-12-01

    In this paper, we consider a low complexity symbol-wise beamforming for MIMO-OFDM systems. We propose a non-iterative algorithm for the symbol-wise beamforming, which can provide the performance approaching that of the conventional symbol-wise beamforming based on the iterative algorithm. We demonstrate that our proposed scheme can reduce the computational complexity significantly. From our simulation results, it is evident that our proposed scheme leads to a negligible performance loss compared to the conventional symbol-wise beamforming regardless of spatial correlation or presence of co-channel interference. © 2011 IEEE.

  4. A water market simulator considering pair-wise trades between agents

    Science.gov (United States)

    Huskova, I.; Erfani, T.; Harou, J. J.

    2012-04-01

    In many basins in England no further water abstraction licences are available. Trading water between water rights holders has been recognized as a potentially effective and economically efficient strategy to mitigate increasing scarcity. A screening tool that could assess the potential for trade through realistic simulation of individual water rights holders would help assess the solution's potential contribution to local water management. We propose an optimisation-driven water market simulator that predicts pair-wise trade in a catchment and represents its interaction with natural hydrology and engineered infrastructure. A model is used to emulate licence-holders' willingness to engage in short-term trade transactions. In their simplest form agents are represented using an economic benefit function. The working hypothesis is that trading behaviour can be partially predicted based on differences in marginal values of water over space and time and estimates of transaction costs on pair-wise trades. We discuss the further possibility of embedding rules, norms and preferences of the different water user sectors to more realistically represent the behaviours, motives and constraints of individual licence holders. The potential benefits and limitations of such a social simulation (agent-based) approach is contrasted with our simulator where agents are driven by economic optimization. A case study based on the Dove River Basin (UK) demonstrates model inputs and outputs. The ability of the model to suggest impacts of water rights policy reforms on trading is discussed.

  5. A dimension-wise analysis method for the structural-acoustic system with interval parameters

    Science.gov (United States)

    Xu, Menghui; Du, Jianke; Wang, Chong; Li, Yunlong

    2017-04-01

    The interval structural-acoustic analysis is mainly accomplished by interval and subinterval perturbation methods. Potential limitations for these intrusive methods include overestimation or interval translation effect for the former and prohibitive computational cost for the latter. In this paper, a dimension-wise analysis method is thus proposed to overcome these potential limitations. In this method, a sectional curve of the system response surface along each input dimensionality is firstly extracted, the minimal and maximal points of which are identified based on its Legendre polynomial approximation. And two input vectors, i.e. the minimal and maximal input vectors, are dimension-wisely assembled by the minimal and maximal points of all sectional curves. Finally, the lower and upper bounds of system response are computed by deterministic finite element analysis at the two input vectors. Two numerical examples are studied to demonstrate the effectiveness of the proposed method and show that, compared to the interval and subinterval perturbation method, a better accuracy is achieved without much compromise on efficiency by the proposed method, especially for nonlinear problems with large interval parameters.

  6. Small Decline In Low-Value Back Imaging Associated With The 'Choosing Wisely' Campaign, 2012-14.

    Science.gov (United States)

    Hong, Arthur S; Ross-Degnan, Dennis; Zhang, Fang; Wharam, J Frank

    2017-04-01

    Choosing Wisely was launched by the American Board of Internal Medicine in April 2012 as a patient- and clinician-targeted campaign to reduce potentially unnecessary "low-value" medical services. The campaign's impact on low- and high-value care beyond its first year is unknown; furthermore, it is unknown whether some patients such as members of consumer-directed health plans and people residing in different US regions have responded more than others. To evaluate the impact of Choosing Wisely, we used commercial insurance claims to track changes in the use of low-value imaging (x-ray, computed tomography, and magnetic resonance imaging) for back pain before and after the campaign began, a period running from 2010 to 2014. We selected back pain imaging because it is a prominent target of Choosing Wisely, which considers it low value except in a minority of cases, because of its relatively high out-of-pocket expense, and the large volume of low back pain visits nationally. We found only a 4 percent relative reduction in low-value back imaging 2.5 years after the start of the campaign and some differences in regional trends, but no differences associated with enrollment in consumer-directed health plans. Our findings highlight the ongoing challenge of reducing unnecessary medical care, even when patients have "skin in the game" under consumer-directed health plans. Project HOPE—The People-to-People Health Foundation, Inc.

  7. Evaluation of Masseter Muscle Thickness and Its Relation with Mandibular Growth Pattern: An Ultrasonographic Study

    Directory of Open Access Journals (Sweden)

    Raj Kumar Singh

    2014-01-01

    Full Text Available Objective: Aims of the study were to measure the thickness of masseter muscle in both males and females of different growth pattern and then to evaluate the relation of thickness of masseter muscle with different growth pattern in both genders. Materials and methods: This was a double-blind study conducted on 40 subjects in the age range of 15 to 24 years consisting of twenty females and twenty males selected for the study based on clinical examination. However four subjects which included four male subjects refused to undergo ultrasonography. Therefore, only thirty-six subjects were undergone ultrasonography. Their ultrasonography was done to measure the masseter muscle thickness. Lateral cephalograms taken to assess their growth pattern. Based on the growth pattern, the subjects were divided into three groups hypodivergents, normodivergents and hyperdivergents and their relation to muscle thickness was evaluated. A null hypothesis was formulated after beginning of study and it was assumed that masseter muscle thickness have no correlation with growth pattern. Results: The results showed significantly (0.05 in both normal and clenched position. Thicker muscle mass was found on the right side as compared to the left side in both males and females whereas gender wise thicker muscle mass was found in males as compared to females. Females showed more variation in muscle thickness values.

  8. Herbal diuretics revisited: from "wise women" to William Withering.

    Science.gov (United States)

    Kinne-Saffran, Eva; Kinne, Rolf K H

    2002-07-01

    This contribution summarizes the use of herbal diuretics over the period of two thousand years. After describing the role of herbs in the framework of the theory of the balance of humors for well-being, it details the contributions of Pliny the Elder (23-79), Dioscorides (40-90), Hildegard von Bingen (1098-1179), Pietro Andrea Matthioli (1500-1577), and Leonard Fuchs (1501-1566) in providing increasingly more precise descriptions and illustrations of medicinal plants. Then, William Withering's (1741-1799) scientific analysis of the use of foxglove for the treatment of dropsy is presented, taking into account the role peasant "wise women" played in his discoveries and the role of "folklore medicine" before him. Copyright 2002 S. Karger AG, Basel

  9. Group-wise functional community detection through joint Laplacian diagonalization.

    Science.gov (United States)

    Dodero, Luca; Gozzi, Alessandro; Liska, Adam; Murino, Vittorio; Sona, Diego

    2014-01-01

    There is a growing conviction that the understanding of the brain function can come through a deeper knowledge of the network connectivity between different brain areas. Resting state Functional Magnetic Resonance Imaging (rs-fMRI) is becoming one of the most important imaging modality widely used to understand network functionality. However, due to the variability at subject scale, mapping common networks across individuals is by now a real challenge. In this work we present a novel approach to group-wise community detection, i.e. identification of functional coherent sub-graphs across multiple subjects. This approach is based on a joint diagonalization of two or more graph Laplacians, aiming at finding a common eigenspace across individuals, over which clustering in fewer dimension can then be applied. This allows to identify common sub-networks across different graphs. We applied our method to rs-fMRI dataset of mouse brain finding most important sub-networks recently described in literature.

  10. Investment in Watershed Services projects: the ClimateWIse project

    Science.gov (United States)

    Brauman, K. A.; Ponette-González, A.; Bremer, L.; Hamel, P.; Floerke, M.; Rocha, H.; Schneider, C.

    2016-12-01

    Millions of people depend on water supplied from páramo grasslands and Andean and Atlantic forests in montane tropical South America. It is thus critical to ensure clean, secure water through climate-resilient source water protection. Through a multidisciplinary, multi-institutional, and multi-country (U.S., Germany, Brazil) partnership, our newly funded project `ClimateWIse' will collaborate with a network of Investment in Watershed Services (IWS) projects to assess the effects of land use and climate change on water resources in this region. In IWS projects, downstream water users support upstream land stewards in undertaking source watershed protection activities. These projects are often sited at high-elevations in data-poor regions, and there is little evidence of their immediate or long-term impact on water quantity or quality. In recent years, many IWS projects have initiated formal monitoring programs. One key goal of ClimateWIse is to compile and analyze this IWS monitoring data, focusing on three sites in Brazil and three in Peru, Ecuador, and Colombia. Using preliminary data from three IWS programs in Brazil - Extrema, Camboriu, and Guandu - we demonstrate how the monitoring design of IWS programs can be combined with regional-scale weather and land use data to quantify land-use change and climate change impacts on water resources in this region. The challenges of ongoing data cleaning and assimilation will be discussed, as will the challenges of comparing data from programs where different types of monitoring programs have been implemented.

  11. Piece-wise mixed integer programming for optimal sizing of surge control devices in water distribution systems

    Science.gov (United States)

    Skulovich, Olya; Bent, Russell; Judi, David; Perelman, Lina Sela; Ostfeld, Avi

    2015-06-01

    Despite their potential catastrophic impact, transients are often ignored or presented ad hoc when designing water distribution systems. To address this problem, we introduce a new piece-wise function fitting model that is integrated with mixed integer programming to optimally place and size surge tanks for transient control. The key features of the algorithm are a model-driven discretization of the search space, a linear approximation nonsmooth system response surface to transients, and a mixed integer linear programming optimization. Results indicate that high quality solutions can be obtained within a reasonable number of function evaluations and demonstrate the computational effectiveness of the approach through two case studies. The work investigates one type of surge control devices (closed surge tank) for a specified set of transient events. The performance of the algorithm relies on the assumption that there exists a smooth relationship between the objective function and tank size. Results indicate the potential of the approach for the optimal surge control design in water systems.

  12. Monitoring and evaluation of seasonal snow cover in Kashmir valley ...

    Indian Academy of Sciences (India)

    Seasonal snow cover is a vital natural resource in the Himalaya. Monitoring of the areal extent of seasonal snow cover is important for both climatological studies as well as hydrological appli- cations. In the present paper, snow cover monitoring was carried out to evaluate the region-wise accumulation and ablation pattern ...

  13. A Closer Look at Chinese EFL Learners' Test-Wiseness Strategies in Reading Test

    Science.gov (United States)

    Haiyan, Miao; Rilong, Liu

    2016-01-01

    This paper reports on an investigation into the relationship of test-takers' use of test-wiseness strategies to Chinese EFL learners' reading test performance. A test-wiseness questionnaire was administered immediately after the final achievement test to probe into how learners thought while completing the reading section of the test. It was found…

  14. Scaling Astro-WISE to LOFAR long term archive. From KIDS to LOFAR

    NARCIS (Netherlands)

    Begeman, K.; Belikov, A. N.; Boxhoorn, D.; Dijkstra, F.; Holties, H. A.; Renting, G. A.; Vermaas, N.; Vriend, W. -J.

    The Astro-WISE information system was developed to handle data processing for the KIDS survey. In this paper we describe the adaptation of the WISE concept to allow scaling to support archives containing tens of petabytes of stored data and the changes we introduced to accommodate the system for the

  15. An optical survey of the Elais-S2 field : Data reduction with Astro-Wise

    NARCIS (Netherlands)

    Héraudeau, Ph.; Valentijn, E.; Casoli, F.; Contini, T.; Hameury, J.M.; Pagani, L.

    2005-01-01

    We use the ASTRO-WISE system to reduce observations on the ELAIS-S2 field obtained in the B, V, R and I-bands with the Wide-Field Imager at the 2.2m ESO/MPG telescope. We present the main data reduction steps performed by the prototype version of ASTRO-WISE.

  16. ISRIC-WISE - Global Soil Profile Data (ver. 3.1)

    NARCIS (Netherlands)

    Batjes, N.H.

    2009-01-01

    Version 3.1 of the ISRIC-WISE database (WISE3) was compiled from a wide range of soil profile data collected by many soil professionals worldwide. All profiles have been harmonized with respect to the original Legend (1974) and Revised Legend (1988) of FAO-Unesco. Thereby, the primary soil data ─

  17. Stimulation of Work Integration Social Enterprises (WISES) and Combatting Social Exclusion at the Local Level

    NARCIS (Netherlands)

    Boesveldt, N.F.|info:eu-repo/dai/nl/162503199

    2016-01-01

    WISES are social enterprises that work with people marginalized from the regular labour market, including people with severe handicaps, with disabilities and those who suffer addiction and homelessness. WISES offer an alternative to regular social programs: they breach social exclusion and stimulate

  18. Automatized Photometric Monitoring of Active Galactic Nuclei with the 46cm Telescope of the Wise Observatory

    Science.gov (United States)

    Pozo Nuñez, Francisco; Chelouche, Doron; Kaspi, Shai; Niv, Saar

    2017-09-01

    We present the first results of an ongoing variability monitoring program of active galactic nuclei (AGNs) using the 46 cm telescope of the Wise Observatory in Israel. The telescope has a field of view of 1.25^\\circ × 0.84^\\circ and is specially equipped with five narrowband filters at 4300, 5200, 5700, 6200, and 7000 Å to perform photometric reverberation mapping studies of the central engine of AGNs. The program aims to observe a sample of 27 AGNs (V time delay measurements obtained in previous works. We describe the autonomous operation of the telescope together with the fully automatic pipeline used to achieve high-performance unassisted observations, data reduction, and light curves extraction using different photometric methods. The science verification data presented here demonstrates the performance of the monitoring program in particular for efficiently photometric reverberation mapping of AGNs with additional capabilities to carry out complementary studies of other transient and variable phenomena such as variable stars studies.

  19. Optimizing Usability Studies by Complementary Evaluation Methods

    NARCIS (Netherlands)

    Schmettow, Martin; Bach, Cedric; Scapin, Dominique

    2014-01-01

    This paper examines combinations of complementary evaluation methods as a strategy for efficient usability problem discovery. A data set from an earlier study is re-analyzed, involving three evaluation methods applied to two virtual environment applications. Results of a mixed-effects logistic

  20. A new scale for assessing wisdom based on common domains and a neurobiological model: The San Diego Wisdom Scale (SD-WISE).

    Science.gov (United States)

    Thomas, Michael L; Bangen, Katherine J; Palmer, Barton W; Sirkin Martin, Averria; Avanzino, Julie A; Depp, Colin A; Glorioso, Danielle; Daly, Rebecca E; Jeste, Dilip V

    2017-09-08

    Wisdom is an ancient concept that has gained new interest among clinical researchers as a complex trait relevant to well-being and healthy aging. As the empirical data regarding wisdom have grown, several measures have been used to assess an individual's level of wisdom. However, none of these measures has been based on a construct of wisdom with neurobiological underpinnings. We sought to develop a new scale, the San Diego Wisdom Scale (SD-WISE), which builds upon recent gains in the understanding of psychological and neurobiological models of the trait. Data were collected from 524 community-dwelling adults age 25-104 years as part of a structured multi-cohort study of adult lifespan. Participants were administered the SD-WISE along with two existing measures of wisdom that have been shown to have good psychometric properties. Factor analyses confirmed the hypothesized measurement model. SD-WISE total scores were reliable, demonstrated convergent and discriminant validity, and correlated, as hypothesized, negatively with emotional distress, but positively with well-being. However, the magnitudes of these associations were small, suggesting that the SD-WISE is not just a global measure of mental state. The results support the reliability and validity of SD-WISE scores. Study limitations are discussed. The SD-WISE, with good psychometric properties, a brief administration time, and a measurement model that is consistent with commonly cited content domains of wisdom based on a putative neurobiological model, may be useful in clinical practice as well as in bio-psycho-social research, especially investigations into the neurobiology of wisdom and experimental interventions to enhance wisdom. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Statistical analysis on activation and photo-bleaching of step-wise multi-photon activation fluorescence of melanin

    Science.gov (United States)

    Gu, Zetong; Lai, Zhenhua; Zhang, Xi; Yin, Jihao; DiMarzio, Charles A.

    2015-03-01

    Melanin is regarded as the most enigmatic pigments/biopolymers found in most organisms. We have shown previously that melanin goes through a step-wise multi-photon absorption process after the fluorescence has been activated with high laser intensity. No melanin step-wise multi-photon activation fluorescence (SMPAF) can be obtained without the activation process. The step-wise multi-photon activation fluorescence has been observed to require less laser power than what would be expected from a non-linear optical process. In this paper, we examined the power dependence of the activation process of melanin SMPAF at 830nm and 920nm wavelengths. We have conducted research using varying the laser power to activate the melanin in a point-scanning mode for multi-photon microscopy. We recorded the fluorescence signals and position. A sequence of experiments indicates the relationship of activation to power, energy and time so that we can optimize the power level. Also we explored regional analysis of melanin to study the spatial relationship in SMPAF and define three types of regions which exhibit differences in the activation process.

  2. Organizational evaluation of an interprofessional study unit

    DEFF Research Database (Denmark)

    Jensen, Didde Cramer; Nørgaard, Birgitte; Draborg, Eva

    2012-01-01

    This article presents results from an organizational evaluation of an interprofessional clinical study unit (ICS) in Denmark. The aim of this study was to test whether the ICS was based on a durable organizational concept and to identify the prerequisites for the unit to be successful. The evalua......This article presents results from an organizational evaluation of an interprofessional clinical study unit (ICS) in Denmark. The aim of this study was to test whether the ICS was based on a durable organizational concept and to identify the prerequisites for the unit to be successful...

  3. Chain-Wise Generalization of Road Networks Using Model Selection

    Science.gov (United States)

    Bulatov, D.; Wenzel, S.; Häufel, G.; Meidow, J.

    2017-05-01

    Streets are essential entities of urban terrain and their automatized extraction from airborne sensor data is cumbersome because of a complex interplay of geometric, topological and semantic aspects. Given a binary image, representing the road class, centerlines of road segments are extracted by means of skeletonization. The focus of this paper lies in a well-reasoned representation of these segments by means of geometric primitives, such as straight line segments as well as circle and ellipse arcs. We propose the fusion of raw segments based on similarity criteria; the output of this process are the so-called chains which better match to the intuitive perception of what a street is. Further, we propose a two-step approach for chain-wise generalization. First, the chain is pre-segmented using circlePeucker and finally, model selection is used to decide whether two neighboring segments should be fused to a new geometric entity. Thereby, we consider both variance-covariance analysis of residuals and model complexity. The results on a complex data-set with many traffic roundabouts indicate the benefits of the proposed procedure.

  4. The Piece Wise Linear Reactive Flow Rate Model

    Science.gov (United States)

    Vitello, Peter; Souers, P. Clark

    2006-07-01

    For non-ideal explosives a wide range of behavior is observed in experiments dealing with differing sizes and geometries. A predictive detonation model must be able to reproduce many phenomena including such effects as: variations in the detonation velocity with the radial diameter of rate sticks; slowing of the detonation velocity around gentle corners; production of dead zones for abrupt corner turning; failure of small diameter rate sticks; and failure for rate sticks with sufficiently wide cracks. Most models have been developed to explain one effect at a time. Often, changes are made in the input parameters used to fit each succeeding case with the implication that this is sufficient for the model to be valid over differing regimes. We feel that it is important to develop a model that is able to fit experiments with one set of parameters. To address this we are creating a new generation of models that are able to produce better fitting to individual data sets than prior models and to simultaneous fit distinctly different regimes of experiments. Presented here are details of our new Piece Wise Linear reactive flow model applied to LX-17.

  5. Transformation Invariant Control of Voxel-Wise False Discovery Rate

    Science.gov (United States)

    Li, Junning; Shi, Yonggang; Toga, Arthur W.

    2016-01-01

    Multiple testing for statistical maps remains a critical and challenging problem in brain mapping. Since the false discovery rate (FDR) criterion was introduced to the neuroimaging community a decade ago, many variations have been proposed, mainly to enhance detection power. However, a fundamental geometrical property known as transformation invariance has not been adequately addressed, especially for the voxel-wise FDR. Correction of multiple testing applied after spatial transformation is not necessarily equivalent to transformation applied after correction in the original space. Without the invariance property, assigning different testing spaces will yield different results. We find that normalized residuals of linear models with Gaussian noises are uniformly distributed on a unit high-dimensional sphere, independent of t-statistics and F-statistics. By defining volumetric measure in the hyper-spherical space mapped by normalized residuals, instead of the image’s Euclidean space, we can achieve invariant control of the FDR under diffeomorphic transformation. This hyper-spherical measure also reflects intrinsic “volume of randomness” in signals. Experiments with synthetic, semi-synthetic and real images demonstrate that our method significantly reduces FDR inconsistency introduced by the choice of testing spaces. PMID:27101602

  6. Efficient MAC Protocol for Subcarrier-Wise Rate Adaptation over WLAN

    Directory of Open Access Journals (Sweden)

    Sung Won Kim

    2010-01-01

    Full Text Available While bit-loading algorithms over wireless systems have been extensively studied, the development of a protocol which implements bit-loading-based rate adaptation over wireless systems has not been highlighted. The design of such a protocol is not a trivial problem, due to the overhead associated with the feedback information. In this paper, a novel protocol is proposed to provide an efficient way to implement subcarrier-wise rate adaptation in OFDM-based wireless systems. When receiving a Ready-To-Send (RTS packet, the receiver determines the number of bits to be allocated on each subcarrier through channel estimation. This decision is delivered to the sender using an additional OFDM symbol in the Clear-To-Send (CTS packet. That is, bit-allocation over subcarriers is achieved using only one additional OFDM symbol. The protocol enhances the channel efficiency in spite of the overhead of one additional OFDM symbol.

  7. QUARTER-WISE COMPARATIVE PREVALENCE OF MASTITIS IN BUFFALOES AND CROSSBRED COWS

    Directory of Open Access Journals (Sweden)

    A. Z. Khan and G. Muhammad1

    2005-01-01

    Full Text Available The present study was designed to determine the quarter-wise comparative prevalence of mastitis in buffaloes and crossbred cows. Milk samples collected from 50 dairy buffaloes and 50 crossbred cows were tested for subclinical mastitis by Surf Field Mastitis Test. In addition, all milk samples were processed for isolation and identification of pathogens. In buffaloes, overall prevalence of subclinical mastitis was 27%, clinical mastitis 4% and blind quarters 10%. In crossbred cows, subclinical mastitis was observed in 36%, clinical mastitis in 5.5% and blind quarters in 8% quarters. Prevalence was higher (32% in hindquarters of crossbred cows than those of buffaloes (29%. Among the isolates, Staphylococcus aureus showed the highest (45% frequency, followed by Streptococcus agalactiae (23%, E. coli (18% and Bacillus spp. (14% in buffaloes. In case of crossbred cows, Staphylococcus aureus , Streptococcus agalactiae , E. coli and Bacillus spp. were isolated from 48, 30, 13 and 8% milk samples respectively.

  8. PairWise Neighbours database: overlaps and spacers among prokaryote genomes

    Directory of Open Access Journals (Sweden)

    Garcia-Vallvé Santiago

    2009-06-01

    Full Text Available Abstract Background Although prokaryotes live in a variety of habitats and possess different metabolic and genomic complexity, they have several genomic architectural features in common. The overlapping genes are a common feature of the prokaryote genomes. The overlapping lengths tend to be short because as the overlaps become longer they have more risk of deleterious mutations. The spacers between genes tend to be short too because of the tendency to reduce the non coding DNA among prokaryotes. However they must be long enough to maintain essential regulatory signals such as the Shine-Dalgarno (SD sequence, which is responsible of an efficient translation. Description PairWise Neighbours is an interactive and intuitive database used for retrieving information about the spacers and overlapping genes among bacterial and archaeal genomes. It contains 1,956,294 gene pairs from 678 fully sequenced prokaryote genomes and is freely available at the URL http://genomes.urv.cat/pwneigh. This database provides information about the overlaps and their conservation across species. Furthermore, it allows the wide analysis of the intergenic regions providing useful information such as the location and strength of the SD sequence. Conclusion There are experiments and bioinformatic analysis that rely on correct annotations of the initiation site. Therefore, a database that studies the overlaps and spacers among prokaryotes appears to be desirable. PairWise Neighbours database permits the reliability analysis of the overlapping structures and the study of the SD presence and location among the adjacent genes, which may help to check the annotation of the initiation sites.

  9. OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments

    Directory of Open Access Journals (Sweden)

    Arkin Adam P

    2006-01-01

    Full Text Available Abstract Background Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no systematic errors in the data even though several sources of systematic error are known. Results OpWise estimates the amount of systematic error in bacterial microarray data by assuming that genes in the same operon have matching expression patterns. OpWise then performs a Bayesian analysis of a linear model to estimate significance. In simulations, OpWise corrects for systematic error and is robust to deviations from its assumptions. In several bacterial data sets, significant amounts of systematic error are present, and replicate-based approaches overstate the confidence of the changers dramatically, while OpWise does not. Finally, OpWise can identify additional changers by assigning genes higher confidence if they are consistent with other genes in the same operon. Conclusion Although microarray data can contain large amounts of systematic error, operons provide an external standard and allow for reasonable estimates of significance. OpWise is available at http://microbesonline.org/OpWise.

  10. 77 FR 49775 - Beaverhead-Deerlodge National Forest, Wisdom and Wise River Ranger Districts; Montana; North and...

    Science.gov (United States)

    2012-08-17

    ... Forest Service Beaverhead-Deerlodge National Forest, Wisdom and Wise River Ranger Districts; Montana..., Wisdom/Wise River District Ranger at (406) 689-3243 or via email at [email protected] . Individuals who... Official The Wisdom/Wise River District Ranger will be the responsible official. Nature of Decision To Be...

  11. A Structural Equation Model (SEM) of the Impact of Transformational, Visionary, Charismatic and Ethical Leadership Styles on the Development of Wise Leadership among Filipino Private Secondary School Principals

    Science.gov (United States)

    Parco-Tropicales, Marishirl; de Guzman, Allan B.

    2014-01-01

    In recent years, wisdom is seen as a key resource for school leaders in dealing with the dynamics of the changing school environments. This study purports to expand the growing interest on wisdom by testing a model that describes the impact of transformational, visionary, charismatic and ethical leadership styles on wise leadership development…

  12. The Fastest Galaxy Evolution in an Unbiased Compact Group Sample with WISE

    Science.gov (United States)

    Lee, Gwang-Ho; Hwang, Ho Seong; Sohn, Jubee; Lee, Myung Gyoon

    2017-02-01

    We study the mid-infrared (MIR) properties of galaxies in compact groups and their environmental dependence using the Wide-field Infrared Survey Explorer (WISE) data. We use a volume-limited sample of 670 compact groups and their 2175 member galaxies with {M}rSohn et al., which were identified using a friends-of-friends algorithm. Among the 2175 galaxies, 1541 galaxies are detected at WISE 12 μ {{m}} with a signal-to-noise ratio greater than 3. Among the 1541 galaxies, 433 AGN-host galaxies are identified by using both optical and MIR classification schemes. Using the remaining 1108 non-AGN galaxies, we find that the MIR [3.4]-[12] colors of compact group early-type galaxies are on average bluer than those of cluster early-type galaxies. When compact groups have both early- and late-type member galaxies, the MIR colors of the late-type members in those compact groups are bluer than the MIR colors of cluster late-type galaxies. As compact groups are located in denser regions, they tend to have larger early-type galaxy fractions and bluer MIR color galaxies. These trends are also seen for neighboring galaxies around compact groups. However, compact group member galaxies always have larger early-type galaxy fractions and bluer MIR colors than their neighboring galaxies. Our findings suggest that the properties of compact group galaxies depend on both internal and external environments of compact groups, and that galaxy evolution is faster in compact groups than in the central regions of clusters.

  13. The Challenge of Studying Evaluation Theory.

    Science.gov (United States)

    King, Jean A.

    2003-01-01

    Discusses why evaluation has a field has not studied its own theory systematically and examines the tensions between the often-cited claim of K. Lewin that there is noting as practical as a good theory and the response of M. Fullan that there is nothing as theoretical as good practice. (Author/SLD)

  14. Global Data Set of Derived Soil Properties, 0.5-Degree Grid (ISRIC-WISE)

    Data.gov (United States)

    National Aeronautics and Space Administration — The World Inventory of Soil Emission Potentials (WISE) database was used to generate a series of uniform data sets of derived soil properties for each of the 106...

  15. IceBridge WISE L2 Ice Thickness and Surface Elevation V001

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains depth sounder measurements of elevation, surface, bottom, and thickness for Alaska taken from the Warm Ice Sounding Explorer (WISE). The data...

  16. Battle-Wise: Seeking Time-Information Superiority in Networked Warfare

    National Research Council Canada - National Science Library

    Gompert, David C; Lachow, Irving; Perkins, Justin; Smith, Raymond C; Wells, Linton

    2006-01-01

    .... This is not so in the 21st century. Taking the information revolution as a starting point, Battle-Wise argues that only by strengthening the relationship between information technology and brain matter will the U.S...

  17. SAFARI 2000 Derived Soil Properties, 0.5-Deg (ISRIC-WISE)

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: The data set consists of a southern African subset of the ISRIC-WISE global data set of derived soil properties. The World Inventory of Soil Emission...

  18. Global Data Set of Derived Soil Properties, 0.5-Degree Grid (ISRIC-WISE)

    Data.gov (United States)

    National Aeronautics and Space Administration — ABSTRACT: The World Inventory of Soil Emission Potentials (WISE) database was used to generate a series of uniform data sets of derived soil properties for each of...

  19. The Astro-Wise system: a federated information accumulator for astronomy

    NARCIS (Netherlands)

    Valentijn, Edwin A.; Verdoes Kleijn, Gijs

    2007-01-01

    The Astro-Wise consortium has designed a new paradigm, ‘Awe‘, and implemented a fully scalable and distributed information system to overcome the huge information avalanche in wide-field astronomical imaging Surveys.

  20. Using the thoughts on teen parenting survey to determine the impact of Wise Guys.

    Science.gov (United States)

    Herrman, Judith W; Moore, Christopher C; Sims, Regina

    2013-04-01

    The purpose of this project was to determine if the Wise Guys program influences young men's perceptions of the impact a teen birth would have on their lives in the areas of relationships, vocation, and personal life. The Wise Guys program was implemented with 70 adolescent males. The Thoughts on Teen Parenting Survey was used to determine participants' perceptions of the costs and rewards associated with teen parenting. Data, analyzed using paired t-tests, demonstrated that Wise Guys was effective in reinforcing less positive perceptions of teen parenting. Wise Guys offers an important strategy to impact young men's perceptions about the teen parenting experience and provides one means to promote responsible sexual behavior in teen men. © 2012, Wiley Periodicals, Inc.

  1. Investigating the origin of X-ray variability through XMM-Newton and WISE data

    Science.gov (United States)

    Zaino, A.; Vignali, C.; Severgnini, P.; Della Ceca, R.; Ballo, L.

    2017-10-01

    An efficient diagnostic method to find local (zmethod outlined above using the latest 3XMM and WISE data, and I investigated its potentialities in finding interesting spectrally variable (including changing-look) XMM-Newton sources.

  2. Global dynamics of a piece-wise epidemic model with switching vaccination strategy

    OpenAIRE

    Wang, Aili; Xiao, Yanni; Cheke, Robert A.

    2014-01-01

    A piece-wise epidemic model of a switching vaccination program, implemented once the number of people exposed to a disease-causing virus reaches a critical level, is proposed. In addition, variation or uncertainties in interventions are examined with a perturbed system version of the model. We also analyzed the global dynamic behaviors of both the original piece-wise system and the perturbed version theoretically, using generalized Jacobian theory, Lyapunov constants for a non-smooth vector f...

  3. WISE J163940.83-684738.6: A Y DWARF IDENTIFIED BY METHANE IMAGING

    Energy Technology Data Exchange (ETDEWEB)

    Tinney, C. G.; Salter, Graeme [Department of Astrophysics, School of Physics, University of New South Wales, Sydney, NSW 2052 (Australia); Faherty, Jacqueline K. [Department of Astronomy, University of Chile, Camino El Observatorio 1515, Casilla 36-D, Santiago (Chile); Kirkpatrick, J. Davy; Gelino, Christopher R.; Griffith, Roger L. [Infrared Processing and Analysis Center, MS 100-22, California Institute of Technology, Pasadena, CA 91125 (United States); Wright, Edward L. [Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095-1547 (United States); Cushing, Michael C., E-mail: c.tinney@unsw.edu.au [Department of Physics and Astronomy, MS 111, University of Toledo, 2801 W. Bancroft St., Toledo, OH 43606-3328 (United States)

    2012-11-01

    We have used methane imaging techniques to identify the near-infrared counterpart of the bright Wide-field Infrared Survey Explorer (WISE) source WISE J163940.83-684738.6. The large proper motion of this source ( Almost-Equal-To 3.''0 yr{sup -1}) has moved it, since its original WISE identification, very close to a much brighter background star-it currently lies within 1.''5 of the J = 14.90 {+-} 0.04 star 2MASS 16394085-6847446. Observations in good seeing conditions using methane-sensitive filters in the near-infrared J band with the FourStar instrument on the Magellan 6.5 m Baade telescope, however, have enabled us to detect a near-infrared counterpart. We have defined a photometric system for use with the FourStar J2 and J3 filters, and this photometry indicates strong methane absorption, which unequivocally identifies it as the source of the WISE flux. Using these imaging observations we were then able to steer this object down the slit of the Folded-port Infrared Echellette spectrograph on a night of 0.''6 seeing, and so obtain near-infrared spectroscopy confirming a Y0-Y0.5 spectral type. This is in line with the object's near-infrared-to-WISE J3 - W2 color. Preliminary astrometry using both WISE and FourStar data indicates a distance of 5.0 {+-} 0.5 pc and a substantial tangential velocity of 73 {+-} 8 km s{sup -1}. WISE J163940.83-684738.6 is the brightest confirmed Y dwarf in the WISE W2 passband and its distance measurement places it among the lowest luminosity sources detected to date.

  4. Evaluation of remineralizing potential of commercially available child formula dentifrices: An in vitro study

    Directory of Open Access Journals (Sweden)

    Apurva Jagdish Gujarathi

    2015-01-01

    Full Text Available Aim: The aim of this in vitro study is to evaluate the remineralizing potential of commercially available low fluoride child formula dentifrice on primary teeth. Materials and Methods: Total 30 primary teeth were placed in demineralizing solution for 96 hours to produce artificial carious lesions of approximately 100 μm depth, and then cut longitudinally into 30 sections of 100-150 μm thickness and randomly assigned to three groups. Sections were treated with dentifrices containing Colgate ® (anti tooth decay 500 ppm NaF, Cheerio gel ® 458 ppm MFP and Vicco ® non-fluoridated dentifrice. Lesions were evaluated using polarized light microscopy. Results: Colgate ® (anti tooth decay 500 ppm NaF sections exhibited a statistically significant decrease in lesion depth (P < 0.05, paired t-test, whereas those in Cheerio gel ® 458 ppm MFP showed a decrease in lesion depth but was not statistically significant. Vicco ® non-fluoridated dentifrice showed increase in lesion depth. Statistics: A paired t-test is used to evaluate pre- and post-treatment lesion depth measurements, and Newman-Keuls multiple post hoc procedures was carried out to compare pair-wise difference of pre- and post-treatment lesion depth. Conclusion: The Colgate ® (anti tooth decay 500 ppm NaF dentifrice and Cheerio gel ® 458 ppm MFP demonstrated remineralization of carious lesions by virtue of decrease in lesion depth, whereas Vicco ® non-fluoridated dentifrice showed increase in lesion depth.

  5. The predator-prey models for the mechanism of autocatalysis, pair wise interactions and movements to free places

    Directory of Open Access Journals (Sweden)

    Muhammad Shakil

    2015-12-01

    Full Text Available In this paper we aim to develop the modeled equations for different types of mechanism of the predator-prey interactions with the help of a quasi chemical approach while taking a special study case of foxes and rabbits, these mechanisms include autocatalysis mechanism, pair wise interactions and the mechanism of their movements to some free places. The chemical reactions representing the interactions obey the mass action law. The territorial animal like fox is assigned a simple cell as its territory. Under the proper relations between coefficients, this system may demonstrate globally stable dynamics.

  6. Infrared small target and background separation via column-wise weighted robust principal component analysis

    Science.gov (United States)

    Dai, Yimian; Wu, Yiquan; Song, Yu

    2016-07-01

    When facing extremely complex infrared background, due to the defect of l1 norm based sparsity measure, the state-of-the-art infrared patch-image (IPI) model would be in a dilemma where either the dim targets are over-shrinked in the separation or the strong cloud edges remains in the target image. In order to suppress the strong edges while preserving the dim targets, a weighted infrared patch-image (WIPI) model is proposed, incorporating structural prior information into the process of infrared small target and background separation. Instead of adopting a global weight, we allocate adaptive weight to each column of the target patch-image according to its patch structure. Then the proposed WIPI model is converted to a column-wise weighted robust principal component analysis (CWRPCA) problem. In addition, a target unlikelihood coefficient is designed based on the steering kernel, serving as the adaptive weight for each column. Finally, in order to solve the CWPRCA problem, a solution algorithm is developed based on Alternating Direction Method (ADM). Detailed experiment results demonstrate that the proposed method has a significant improvement over the other nine classical or state-of-the-art methods in terms of subjective visual quality, quantitative evaluation indexes and convergence rate.

  7. Multiobjective Level-Wise Scientific Workflow Optimization in IaaS Public Cloud Environment

    Directory of Open Access Journals (Sweden)

    Phyo Thandar Thant

    2017-01-01

    Full Text Available Cloud computing in the field of scientific applications such as scientific big data processing and big data analytics has become popular because of its service oriented model that provides a pool of abstracted, virtualized, dynamically scalable computing resources and services on demand over the Internet. However, resource selection to make the right choice of instances for a certain application of interest is a challenging problem for researchers. In addition, providing services with optimal performance at the lowest financial resource deployment cost based on users’ resource selection is quite challenging for cloud service providers. Consequently, it is necessary to develop an optimization system that can provide benefits to both users and service providers. In this paper, we conduct scientific workflow optimization on three perspectives: makespan minimization, virtual machine deployment cost minimization, and virtual machine failure minimization in the cloud infrastructure in a level-wise manner. Further, balanced task assignment to the virtual machine instances at each level of the workflow is also considered. Finally, system efficiency verification is conducted through evaluation of the results with different multiobjective optimization algorithms such as SPEA2 and NSGA-II.

  8. Step-Wise Velocity of an Air Bubble Rising in a Vertical Tube Filled with a Liquid Dispersion of Nanoparticles.

    Science.gov (United States)

    Cho, Heon Ki; Nikolov, Alex D; Wasan, Darsh T

    2017-03-21

    The motion of air bubbles in tubes filled with aqueous suspensions of nanoparticles (nanofluids) is of practical interest for bubble jets, lab-on-a-chip, and transporting media. Therefore, the focus of this study is the dynamics of air bubbles rising in a tube in a nanofluid. Many authors experimentally and analytically proposed that the velocity of rising air bubbles is constant for long air bubbles suspended in a vertical tube in common liquids (e.g. an aqueous glycerol solution) when the capillary number is larger than 10-4. For the first time, we report here a systematic study of an air bubble rising in a vertical tube in a nanofluid (e.g. an aqueous silica dioxide nanoparticle suspension, nominal particle size, 19 nm). We varied the bubble length scaled by the diameter of the tubes (L/D), the concentration of the nanofluid (10 and 12.5 v %), and the tube diameter (0.45, 0.47, and 0.50 cm). The presence of the nanoparticles creates a significant change in the bubble velocity compared with the bubble rising in the common liquid with the same bulk viscosity. We observed a novel phenomenon of a step-wise increase in the air bubble rising velocity versus bubble length for small capillary numbers less than 10-7. This step-wise velocity increase versus the bubble length was not observed in a common fluid. The step-wise velocity increase is attributed to the nanoparticle self-layering phenomenon in the film adjacent to the tube wall. To elucidate the role of the nanoparticle film self-layering on the bubble rising velocity, the effect of the capillary number, the tube diameter (e.g. the capillary pressure), and nanofilm viscosity are investigated. We propose a model that takes into consideration the nanoparticle layering in the film confinement to explain the step-wise velocity phenomenon versus the length of the bubble. The oscillatory film interaction energy isotherm is calculated and the Frenkel approach is used to estimate the film viscosity.

  9. Responses to Fever Overnight: Do Residents Choose Wisely?

    Science.gov (United States)

    Howard-Anderson, Jessica; Schwab, Kristin; Chang, Sandy; Graber, Christopher J; Quinn, Roswell

    2017-01-01

    Abstract Background Residents at our institution rely heavily on the terminology “Full Fever Work Up” (FFWU) as a cognitive tool for cross-covering patients with a fever. Prior survey data revealed that residents vary considerably in how they respond to fevers and what FFWU means. We sought to determine what tests are included in the FFWU, how often the term is adhered to, and if it significantly changes clinical outcomes. Methods For 3 months, study investigators collected FFWU instructions for patients who experienced a fever at night. For each febrile episode, investigators reviewed chart data on patient factors, circumstances surrounding the fever, tests ordered, etiologies of the fever, and outcomes (immediately and 30-days after the fever). The UCLA Institutional Review Board approved this study. Results We reviewed 253 fever episodes. For 204 episodes, written sign-out by the primary team was available. 59% of the fevers were in male patients and the mean age was 59 years. 12% had an organ transplant and 45% qualified as highly immunocompromised. 79% met SIRS criteria, whereas only 3% met qSOFA criteria and 2% required escalation of care. The cross-covering physician wrote a note in 4% of the cases and evaluated the patient in-person in 12% of the cases per chart review. Residents most often ordered bacterial blood cultures (48%), followed by urinary tests (34%) and chest X-rays (30%). These tests, as well as fungal blood cultures, lactate and CBC, were significantly more likely to be ordered by the cross-covering resident if the sign-out instructed to perform a FFWU. The mean number of diagnostic tests ordered was 2 and residents started or changed antibiotics in 14% of cases. 88% of the time patients were alive 30 days after their fever. 11% had an antibiotic-related complication and 8% of blood cultures drawn were positive. Conclusion Ordering practices overnight were significantly influenced by the FFWU sign-out instructions, yet evaluating the

  10. Expermental Studies of quantitative evaluation using HPLC

    Directory of Open Access Journals (Sweden)

    Ki Rok Kwon

    2005-06-01

    Full Text Available Methods : This study was conducted to carry out quantitative evaluation using HPLC Content analysis was done using HPLC Results : According to HPLC analysis, each BVA-1 contained approximately 0.36㎍ melittin, and BVA-2 contained approximately 0.54㎍ melittin. But the volume of coating was so minute, slight difference exists between each needle. Conclusion : Above results indicate that the bee venom acupuncture can complement shortcomings of syringe usage as a part of Oriental medicine treatment, but extensive researches should be done for further verification.

  11. Overdensities of SMGs around WISE-selected, ultraluminous, high-redshift AGNs

    Science.gov (United States)

    Jones, Suzy F.; Blain, Andrew W.; Assef, Roberto J.; Eisenhardt, Peter; Lonsdale, Carol; Condon, James; Farrah, Duncan; Tsai, Chao-Wei; Bridge, Carrie; Wu, Jingwen; Wright, Edward L.; Jarrett, Tom

    2017-08-01

    We investigate extremely luminous dusty galaxies in the environments around Wide-field Infrared Survey Explorer (WISE)-selected hot dust-obscured galaxies (Hot DOGs) and WISE/radio-selected active galactic nuclei (AGNs) at average redshifts of z = 2.7 and 1.7, respectively. Previous observations have detected overdensities of companion submillimetre-selected sources around 10 Hot DOGs and 30 WISE/radio AGNs, with overdensities of ˜2-3 and ˜5-6, respectively. We find that the space densities in both samples to be overdense compared to normal star-forming galaxies and submillimetre galaxies (SMGs) in the Submillimetre Common-User Bolometer Array 2 (SCUBA-2) Cosmology Legacy Survey (S2CLS). Both samples of companion sources have consistent mid-infrared (mid-IR) colours and mid-IR to submm ratios as SMGs. The brighter population around WISE/radio AGNs could be responsible for the higher overdensity reported. We also find that the star formation rate densities are higher than the field, but consistent with clusters of dusty galaxies. WISE-selected AGNs appear to be good signposts for protoclusters at high redshift on arcmin scales. The results reported here provide an upper limit to the strength of angular clustering using the two-point correlation function. Monte Carlo simulations show no angular correlation, which could indicate protoclusters on scales larger than the SCUBA-2 1.5-arcmin scale maps.

  12. Sifting planetary mass objects at the limits of the WISE survey

    Science.gov (United States)

    Pinfield, David James; Leggett, Sandy; Gromadzki, Mariusz

    2015-08-01

    Large scale infrared imaging surveys have facilitated the discovery of sub-stellar objects in the field and as wide companions, with mass down to a few Jupiters and Teff as low as ~250K. This population may have diverse origins with formation in both circumstellar and interstellar environments, with much work still needed to properly understand the "brown dwarf-exoplanet connection". The Wide-field Infrared Survey Explorer (WISE) is currently providing the greatest sensitivity to free-floating planetary mass objects, and has revealed a new classification that covers "habitable zone" temperatures - the Y dwarfs. WISE scans the sky in a way that yields time-domain as well as colour/brightness/morphology information, and offers an expanded opportunity to discriminate between genuine sources and noise signatures near the survey limits, as well as scope to reveal very high proper motion objects in the solar neighbourhood. I have developed a Bayesian search methodology to identify the coolest faintest objects in WISE, from within the reservoir of faint contamination and noise signals. I define multi-parameter probability distributions using controlled sampling of the AllWISE database. The coolest sub-stellar objects are detected in the WISE W2 band, but are un-detected at W1, so my analysis prioritises sources that display source-like and noise-like properties respectively in these two bands. I will review the followup observations that allow me to confirm or reject candidate Y dwarfs, and present recent discoveries from the programme.

  13. Choosing wisely for syncope: low-value carotid ultrasound use.

    Science.gov (United States)

    Scott, John W; Schwartz, Aaron L; Gates, Jonathan D; Gerhard-Herman, Marie; Havens, Joaquim M

    2014-08-13

    The United States spends more than $750 billion annually on tests and procedures that do not benefit patients. Although there is no physiological indication for carotid ultrasound in "simple" syncope in the absence of focal neurological signs or symptoms suggestive of stroke, there is concern that this practice remains common for routine syncope workups. We used a 5% random-sample Medicare claims database to evaluate large-scale national trends in utilization of low-value carotid ultrasound imaging for simple syncope. We found that 16.5% of all Medicare beneficiaries with simple syncope underwent carotid imaging and 6.5% of all carotid ultrasounds ordered in 2009 were for this low-value indication. These findings were complemented by a manual chart review of 313 patients at a large academic medical center who underwent carotid ultrasound for simple syncope over a 5-year period. For the 48 (15.4%) of 313 patients with stenosis ≥50%, carotid ultrasound did not yield a causal diagnosis. Only 2% of the 313 patients imaged experienced a change in medications after a positive study, and low-value care. © 2014 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  14. SuperWiseNet - a unique network platform to leverage student entrepreneurship projects

    DEFF Research Database (Denmark)

    Gertsen, Frank; Høgsaa, Asger; Tollestrup, Christian H. T.

    2016-01-01

    and an experience-enriched forum consisting of teachers, industry experts, entrepreneurs and specialty consultants. The interaction unfolds as a series of workshops facilitating the progression of the student teams’ four months project work. The students of concern are enrolled in the international Entrepreneurial...... Engineering Master’s Program [1] at Aalborg University, Denmark (120 ECTS credits). The paper will describe and elaborate on the functioning of SuperWiseNet including a discussion of advantages for students, faculty, and industry/externals as well as some challenges with the concept.......The area of interests is the development of a potentially new complementary industry-university component, which has been labelled ‘SuperWiseNet’ for the context of academic entrepreneurial programs. The SuperWiseNet is a network-based platform for interaction between students of entrepreneurship...

  15. Target and (Astro-)WISE technologies Data federations and its applications

    Science.gov (United States)

    Valentijn, E. A.; Begeman, K.; Belikov, A.; Boxhoorn, D. R.; Brinchmann, J.; McFarland, J.; Holties, H.; Kuijken, K. H.; Kleijn, G. Verdoes; Vriend, W.-J.; Williams, O. R.; Roerdink, J. B. T. M.; Schomaker, L. R. B.; Swertz, M. A.; Tsyganov, A.; van Dijk, G. J. W.

    2017-06-01

    After its first implementation in 2003 the Astro-WISE technology has been rolled out in several European countries and is used for the production of the KiDS survey data. In the multi-disciplinary Target initiative this technology, nicknamed WISE technology, has been further applied to a large number of projects. Here, we highlight the data handling of other astronomical applications, such as VLT-MUSE and LOFAR, together with some non-astronomical applications such as the medical projects Lifelines and GLIMPS; the MONK handwritten text recognition system; and business applications, by amongst others, the Target Holding. We describe some of the most important lessons learned and describe the application of the data-centric WISE type of approach to the Science Ground Segment of the Euclid satellite.

  16. Numerical investigation of the wake interaction between two model wind turbines with span-wise offset

    DEFF Research Database (Denmark)

    Sarmast, Sasan; Chivaee, Hamid Sarlak; Ivanell, Stefan

    2014-01-01

    Wake interaction between two model scale wind turbines with span-wise offset is investigated numerically using Large Eddy Simulation (LES) and the results are validated against the experimental data. An actuator line technique is used for modeling the rotor. The investigated setup refers to a ser......Wake interaction between two model scale wind turbines with span-wise offset is investigated numerically using Large Eddy Simulation (LES) and the results are validated against the experimental data. An actuator line technique is used for modeling the rotor. The investigated setup refers...... to a series of experimental measurements of two model scale turbines conducted by NTNU in low speed wind tunnel in which the two wind turbines are aligned with a span-wise offset resulting in half wake interaction. Two levels of free-stream turbulence are tested, the minimum undisturbed level of about Ti ≈ 0...

  17. Public awareness and misunderstanding about DrinkWise Australia: a cross-sectional survey of Australian adults.

    Science.gov (United States)

    Brennan, Emily; Wakefield, Melanie A; Durkin, Sarah J; Jernigan, David H; Dixon, Helen G; Pettigrew, Simone

    2017-08-01

    DrinkWise Australia is an alcohol industry Social Aspects/Public Relations Organisation (SAPRO). We assessed the Australian public's awareness of DrinkWise, beliefs about its funding source, and associations between funding beliefs and perceptions of DrinkWise. A total of 467 adult weekly drinkers completed an online cross-sectional survey in February 2016. Half the sample had heard of DrinkWise (48.6%); of these, the proportion aware that DrinkWise is industry funded (37.0%) was much smaller than the proportion believing it receives government funding (84.1%). Respondents who incorrectly believed DrinkWise receives government funding were more likely to hold a favourable perception of the organisation's credibility, trustworthiness and respectability than those who did not believe it receives government funding (75.9% vs. 58.3%; p=0.032). The drinking population is vulnerable to believing that alcohol industry public relations organisations such as DrinkWise are government funded, which in turn is associated with more favourable perceptions of the organisation's credibility, trustworthiness, and respectability. Implications for public health: Favourable perceptions of DrinkWise may enhance the industry's ability to delay or dilute potentially effective alcohol control policies. Future research should investigate whether educating the public about DrinkWise's alcohol industry funding alters the public's perception of how credible, trustworthy and respectable the organisation is. © 2017 The Authors.

  18. SOLAR DRYING KINETICS OF DATE PALM FRUITS ASSUMING A STEP-WISE AIR TEMPERATURE CHANGE

    Directory of Open Access Journals (Sweden)

    ABDELGHANI BOUBEKRI

    2009-09-01

    Full Text Available The effect of drying using a step-wise temperature change was studied considering the case of indirect solar drying of the date palm fruit (Phoenix dactylifera L.. The followed procedure consists of building drying kinetics by stages of temperatures resulting from drying, in constant conditions, of the same variety of dates from Algerian and Tunisian origin. A law of daily temperature variation prevailed by 60°C, was deduced from a statement of temperature collected on a laboratory solar dryer prototype. Two drying curve equation models were used and some comparisons were discussed. The results obtained for dates from the two origins highlighted different response times by changing the air temperature and showed the possibility of reaching a fruit with standard moisture content in only one day of drying on the basis of initial water contents ranging from 0.40 to 0.65. This moisture range is in practice allotted to rehydrated dates by water immersion in order to enhance their quality. Experiments conducted in a laboratory solar drier under temperatures oscillating around 50°C and 60°C led to the same end up regarding the drying time ensuring a visually appreciable fruit quality. Results obtained by a simple sensorial test revealed a better quality of date fruits treated by solar drying comparing to those issued from industrial heat treatment units.

  19. Low-luminosity Blazars in Wise: A Mid-infrared View of Unification

    Science.gov (United States)

    Plotkin, Richard M.; Anderson, S. F.; Brandt, W. N.; Markoff, S.; Shemmer, O.; Wu, J.

    2012-01-01

    We use the preliminary data release from the Wide-Field Infrared Survey Explorer (WISE) to perform the first statistical study on the mid-infrared (IR) properties of a large number ( 102) of BL Lac objects -- low-luminosity Active Galactic Nuclei (AGN) with a jet beamed toward the Earth. As expected, many BL Lac objects are so highly beamed that their jet synchrotron emission dominates their IR spectral energy distributions (SEDs), and the shape of their SEDs in the IR correlates well with SED peak frequency. In other BL Lac objects, the jet is not strong enough to completely dilute the rest of the AGN, and we do not see observational signatures of the dusty torus from these weakly beamed BL Lac objects. While at odds with simple unification, the missing torus is consistent with recent suggestions that BL Lac objects are fed by radiatively inefficient accretion flows. We discuss implications on the ``nature vs. nurture" debate for FR I and FR II galaxies, and also on the standard orientation-based AGN unification model.

  20. Evaluating Environmental Education Programs Using Case Studies.

    Science.gov (United States)

    Thomas, Ian G.

    1990-01-01

    Described is the evaluation of the Master of Environmental Science program at Monash University (Australia). The design of the evaluation is discussed, and the use of multiple sources of data and an innovative style are highlighted. (Author/CW)

  1. Gender and occupation wise knowledge, Awareness and prevention of tuberculosis among people of district Muzaffarabad AJ & K.

    Science.gov (United States)

    Abbasi, Atif; Rafique, Muhammad; Saghir, Amir; Abbas, Kamran; Shaheen, Shabnum; Abdullah, Farooq

    2016-11-01

    To assess the awareness about the spread and control of tuberculosis as well as to investigate the gender and occupation wise differences among people regarding knowledge and attitude towards tuberculosis in the State of AJ & K. A cross-sectional descriptive study was conducted in district Muzaffarabad and a sample of 4000 respondents was selected by using stratified random sampling technique. The stratification was done with respect to gender and occupation. The occupation wise classification includes households, labors, and shop keepers, government employers, under graduate students of social and natural sciences, medical students and doctors. A close ended structured questionnaire was developed to collect the data and data were analyzed by using SPSS (Statistical Package for Social Sciences). Chi-Square test was used for association and Logistic Regression model was used to find out the most significant risk factors with gender. Majority of the males were more aware of tuberculosis than females regarding different aspects related to tuberculosis. The respondents from household, labors and shopkeepers have less awareness and knowledge than those who belong to other professions. The doctors and medical students have almost 100% awareness and knowledge of tuberculosis. It was examined that all the variables were associated with gender except threat, curable and transmissible. Only three variables mentioned above showed non- significant result, while all other variables were strongly associated with gender. Males were found more aware about TB than females. Moreover, the literate people were more conscious concerning the prevalence and threats of the disease.

  2. Step-Wise Group Screening Designs with Unequal A-Priori Probabilities and Errors in Observations

    Directory of Open Access Journals (Sweden)

    M.M. Manene

    2003-06-01

    Full Text Available The performance of step-wise group screening with unequal a-priori probabilities in terms of the expected number of runs and the expected maximum number of incorrect decisions is considered. A method of obtaining optimal step-wise designs with unequal a-priori probabilities is presented for the case in which the direction of each defective factor is assumed to be known a -priori and observations are subject to error. An appropriate cost function is introduced and the value of the group size which minimizes the expected total cost is obtained.

  3. Work Integration Social Enterprise. WISE som platform for inklusion på arbejdsmarkedet.

    OpenAIRE

    Larsen, Kamilla Terp

    2014-01-01

    The topic of this thesis is Work Integration Social Enterprises in a Danish context. My aim is to define and examine the platform that WISE represents in the Danish labour market. Furthermore, I want to identify current tendencies in the field and look at the potential for WISE to change our way of understanding the labour market. I do this by carrying out an analysis based on Ernesto Laclau and Chantal Mouffe’s discourse theory. I especially find their explanations of the process of arti...

  4. Evaluating Por Nuestra Salud: A Feasibility Study.

    Science.gov (United States)

    Marshall, Brenda; Gonzales, Gustavo; Kernan, William

    2016-01-01

    This feasibility study evaluated the impact of a culturally consistent diabetes educational program, led by a Latino pastor, on Latino community diabetes knowledge levels. Latino adults were recruited from two churches serving Latino populations, one identified as intervention, the other as nonintervention. Both churches received the American Diabetes Association's booklets on diabetes education, "Four Steps to Control Your Diabetes for Life." The intervention group also received weekly reviews of the booklet's information from the church pastor, who was educated about diabetes by a Latino family nurse practitioner. Pre- and postintervention levels of diabetes knowledge were measured using the Diabetes Knowledge Questionnaire. Mean changes in the Diabetes Knowledge Questionnaire (DKQ-24) survey from pretest to posttest indicated a significant increase in knowledge in both groups. Only the grades for the participants from the pastor-led group, however, moved from failure in knowledge to high levels of passing. One hundred percent of intervention group participants reported having read the literature. This pilot study supports the feasibility of a local Latino pastor, as a culturally consistent diabetes educator, to increase Latino parishioner's knowledge of diabetes. © 2015 Society for Public Health Education.

  5. Scaling of the Reasons for Research Assistants’ Career Decision-Making through Pair-wise Comparison Method

    Directory of Open Access Journals (Sweden)

    Nermin KIBRISLIOĞLU UYSAL

    2017-04-01

    Full Text Available The purpose of this study was to investigate the factors that affect research assistants’ career decision-making processes through a scaling study using the pair-wise comparison method. The study was conducted with 166 research assistants from 50 different universities in Turkey who were reached via electronic mail. The results of the study indicate that the most important factor affecting research assistants’ career decision-making is the dynamic nature and openness for improvement of the profession. This was followed by a free working environment, the desire for scientific study and the prestige of the profession. Moreover, the least effective factors in research assistants’ career decision making were determined as family guidance and salary.

  6. HRCT evaluation of microtia: A retrospective study

    Directory of Open Access Journals (Sweden)

    Aruna R Patil

    2012-01-01

    Full Text Available Purpose: To determine external, middle, and inner ear abnormalities on high-resolution computed tomography (HRCT of temporal bone in patients with microtia and to predict anatomic external and middle ear anomalies as well as the degree of functional hearing impairment based on clinical grades of microtia. Materials and Methods: It was a retrospective study conducted on Indian population. Fifty-two patients with microtia were evaluated for external, middle, and inner ear anomalies on HRCT of temporal bone. Clinical grading of microtia was done based on criteria proposed by Weerda et al. in 37 patients and degree of hearing loss was assessed using pure tone audiometry or brainstem-evoked response in 32 patients. Independent statistical correlations of clinical grades of micotia with both external and middle ear anomalies detected on HRCT and the degree of hearing loss were finally obtained. Results: The external, middle, and inner ear anomalies were present in 93.1%, 74.5%, and 2.7% patients, respectively. Combined cartilaginous and bony external auditory canal atresia (EAC was the most common anatomic abnormality in our group of microtia patients. Hypoplastic mesotympanum represented the commonest middle ear anomaly. The incidence of combined ossicular dysplasia and facial canal anomalies was lower as compared to other population groups; however, we recorded a greater incidence of cholesteatoma. Both these factors can have a substantial impact on outcome of patients planned for surgery. We found no significant association between grades of microtia and external or middle ear anomalies. Similarly, no significant association was found between lower grades of microtia (grade I and II and degree of hearing loss. However, association between grade III microtia and degree of hearing loss was significant. A significant association between congenital cholesteatoma and degree of pneumatization of atretic plate and mastoid process not previously studied

  7. Three New Cool Brown Dwarfs Discovered with the Wide-field Infrared Survey Explorer (WISE) and an Improved Spectrum of the Y0 Dwarf WISE J041022.71+150248.4

    Science.gov (United States)

    Cushing, Michael C.; Kirkpatrick, J. Davy; Gelino, Christopher R.; Mace, Gregory N.; Skrutskie, Michael F.; Gould, Andrew

    2014-05-01

    As part of a larger search of Wide-field Infrared Survey Explorer (WISE) data for cool brown dwarfs with effective temperatures less than 1000 K, we present the discovery of three new cool brown dwarfs with spectral types later than T7. Using low-resolution, near-infrared spectra obtained with the NASA Infrared Telescope Facility and the Hubble Space Telescope, we derive spectral types of T9.5 for WISE J094305.98+360723.5, T8 for WISE J200050.19+362950.1, and Y0: for WISE J220905.73+271143.9. The identification of WISE J220905.73+271143.9 as a Y dwarf brings the total number of spectroscopically confirmed Y dwarfs to 17. In addition, we present an improved spectrum (i.e., higher signal-to-noise ratio) of the Y0 dwarf WISE J041022.71+150248.4 that confirms the Cushing et al. classification of Y0. Spectrophotometric distance estimates place all three new brown dwarfs at distances less than 12 pc, with WISE J200050.19+362950.1 lying at a distance of only 3.9-8.0 pc. Finally, we note that brown dwarfs like WISE J200050.19+362950.1 that lie in or near the Galactic plane offer an exciting opportunity to directly measure the mass of a brown dwarf via astrometric microlensing.

  8. Three new cool brown dwarfs discovered with the wide-field infrared survey explorer (WISE) and an improved spectrum of the Y0 dwarf wise J041022.71+150248.4

    Energy Technology Data Exchange (ETDEWEB)

    Cushing, Michael C. [Department of Physics and Astronomy, The University of Toledo, 2801 West Bancroft Street, Toledo, OH 43606 (United States); Kirkpatrick, J. Davy; Gelino, Christopher R. [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Mace, Gregory N. [Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095 (United States); Skrutskie, Michael F. [Department of Astronomy, University of Virginia, Charlottesville, VA 22904 (United States); Gould, Andrew, E-mail: michael.cushing@utoledo.edu [Department of Astronomy, Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States)

    2014-05-01

    As part of a larger search of Wide-field Infrared Survey Explorer (WISE) data for cool brown dwarfs with effective temperatures less than 1000 K, we present the discovery of three new cool brown dwarfs with spectral types later than T7. Using low-resolution, near-infrared spectra obtained with the NASA Infrared Telescope Facility and the Hubble Space Telescope, we derive spectral types of T9.5 for WISE J094305.98+360723.5, T8 for WISE J200050.19+362950.1, and Y0: for WISE J220905.73+271143.9. The identification of WISE J220905.73+271143.9 as a Y dwarf brings the total number of spectroscopically confirmed Y dwarfs to 17. In addition, we present an improved spectrum (i.e., higher signal-to-noise ratio) of the Y0 dwarf WISE J041022.71+150248.4 that confirms the Cushing et al. classification of Y0. Spectrophotometric distance estimates place all three new brown dwarfs at distances less than 12 pc, with WISE J200050.19+362950.1 lying at a distance of only 3.9-8.0 pc. Finally, we note that brown dwarfs like WISE J200050.19+362950.1 that lie in or near the Galactic plane offer an exciting opportunity to directly measure the mass of a brown dwarf via astrometric microlensing.

  9. Economic evaluation of CISM : a pilot study

    DEFF Research Database (Denmark)

    Vogt, Joachim

    2004-01-01

    air traffic controllers, critical incident stress management, CISM, critical incidents, critical incident stress, cost-benefit-analysis, economic evaluation, efficiency, return on investment......air traffic controllers, critical incident stress management, CISM, critical incidents, critical incident stress, cost-benefit-analysis, economic evaluation, efficiency, return on investment...

  10. The Astro-WISE approach to quality control for astronomical data

    NARCIS (Netherlands)

    Mc Farland, John; Helmich, Ewout M.; Valentijn, Edwin A.

    We present a novel approach to quality control during the processing of astronomical data. Quality control in the Astro-WISE Information System is integral to all aspects of data handing and provides transparent access to quality estimators for all stages of data reduction from the raw image to the

  11. Role of supply chain management in the wise use of wood resources

    African Journals Online (AJOL)

    One of the cornerstones of sustainable forestry is the wise use of wood resources to achieve maximum value or benefit for society, while not jeopardizing the future. At the same time forest companies must compete on an international scale, otherwise they themselves risk becoming non-sustainable. Supply chain ...

  12. Choosing wisely--the politics and economics of labeling low-value services.

    Science.gov (United States)

    Morden, Nancy E; Colla, Carrie H; Sequist, Thomas D; Rosenthal, Meredith B

    2014-02-13

    More than 40 medical specialties have identified "Choosing Wisely" lists of five overused or low-value services. But these services vary widely in potential impact on care and spending, and specialty societies often name other specialties' services as low value.

  13. The dipole anisotropy of WISE × SuperCOSMOS number counts

    Science.gov (United States)

    Bengaly, C. A. P.; Novaes, C. P.; Xavier, H. S.; Bilicki, M.; Bernui, A.; Alcaniz, J. S.

    2018-01-01

    We probe the isotropy of the Universe with the largest all-sky photometric redshift dataset currently available, namely WISE × SuperCOSMOS. We search for dipole anisotropy of galaxy number counts in multiple redshift shells within the 0.10 origin of the latter discrepancy is unclear, and improved data may be needed to explain it.

  14. A Moving-Object Index for Efficient Query Processing with PeerWise Location Privacy

    DEFF Research Database (Denmark)

    Lin, Dan; Jensen, Christian S.; Zhang, Rui

    2011-01-01

    attention has been paid to enabling so-called peer-wise privacy—the protection of a user’s location from unauthorized peer users. This paper identifies an important efficiency problem in existing peer-privacy approaches that simply apply a filtering step to identify users that are located in a query range...

  15. Astro-WISE Processing of Wide-field Images and Other Data

    NARCIS (Netherlands)

    Buddelmeijer, H.; Williams, O.R.; McFarland, J. P.; Belikov, A.; Ballester, P.; Egret, D.; Lorente, N.P.F.

    Astro-WISE (Vriend et al. 2012) is the Astronomical Wide-field Imaging System for Europe (Valentijn et al. 2007). It is a scientific information system which consists of hardware and software federated over about a dozen institutes throughout Europe. It has been developed to exploit the ever

  16. A generalization of voxel-wise procedures for highdimensional statistical inference using ridge regression

    DEFF Research Database (Denmark)

    Sjöstrand, Karl; Cardenas, Valerie A.; Larsen, Rasmus

    2008-01-01

    regression to address this issue, allowing for a gradual introduction of correlation information into the model. We make the connections between ridge regression and voxel-wise procedures explicit and discuss relations to other statistical methods. Results are given on an in-vivo data set of deformation...

  17. WISE Infrared Properties of Fermi AGNs JJ Qiu1, JS Zhang1,∗ & Q ...

    Indian Academy of Sciences (India)

    Abstract. The infrared properties of Fermi AGNs were investigated using the survey data of the Wide-field Infrared Survey Explorer (WISE). The results showed: (1) BL Lacs tend to be brighter than FSRQs at. 3.4μm. However, with increase of wavelength, FSRQs tend to be brighter than BL Lacs. (2) FSRQs colours are redder ...

  18. Using PeerWise to Develop a Contributing Student Pedagogy for Postgraduate Psychology

    Science.gov (United States)

    McKenzie, Wendy; Roodenburg, John

    2017-01-01

    The importance of the role of peer and self-assessment in developing formative and sustainable assessment practice in higher education is increasingly becoming evident. PeerWise is an online software tool that engages students in contributing to their own and others' learning by authoring, answering and providing feedback on multiple choice…

  19. Battle-Wise: Seeking Time-Information Superiority in Networked Warfare

    Science.gov (United States)

    2006-07-01

    Any veteran of combat knows it would be wrong to dismiss the importance of intuition and the reliability of snap judgments, even when information is...attributed as much to the learning-sharing-thinking power of the BATTLE-WISE 95 entire culture as to its incandescent ex-chairman, “ Neutron Jack

  20. Sustainable, efficient, and equitable water use: the three pillars under wise freshwater allocation

    NARCIS (Netherlands)

    Hoekstra, Arjen Ysbert

    2014-01-01

    There are many river basins in the world where human water footprint needs to be reduced substantially. This article proposes three pillars under wise freshwater allocation: water footprint caps per river basin, water footprint benchmarks per product, and fair water footprint shares per community.

  1. Submillimetre observations of WISE-selected high-redshift, luminous AGN and their surrounding overdense environments

    Science.gov (United States)

    Jones, Suzy F.

    2016-08-01

    We present JCMT SCUBA-2 850 μm submillimetre (submm) observations of 10 mid-infrared (mid-IR) luminous active galactic nuclei (AGNs), detected by the Wide-field Infrared Survey Explorer (WISE) all-sky IR survey and 30 that have also been detected by the NVSS/FIRST radio survey. These rare sources are selected by their extremely red mid-IR spectral energy distributions (SEDs). Further investigations show that they are highly obscured, have abundant warm AGN-heated dust and are thought to be experiencing intense AGN feedback. When comparing the number of submm galaxies detected serendipitously in the surrounding 1.5 arcmin to those in blank-field submm surveys, there is a very significant overdensity, of order 3-5, but no sign of radial clustering centred at our primary objects. The WISE-selected AGN thus reside in 10-Mpc-scale overdense environments that could be forming in pre-viralized clusters of galaxies. WISE-selected AGNs appear to be the strongest signposts of high-density regions of active, luminous and dusty galaxies. SCUBA-2 850 μm observations indicate that their submm fluxes are low compared to many popular AGN SED templates, hence the WISE/radio-selected AGNs have either less cold and/or more warm dust emission than normally assumed for typical AGN. Most of the targets have total IR luminosities ≥1013 L⊙, with known redshifts of 20 targets between z ˜ 0.44-4.6.

  2. Integration of the MUSE Software Pipeline into the Astro-WISE System

    NARCIS (Netherlands)

    Pizagno, J.; Streicher, O.; Vriend, W.-J.; Ballester, P.; Egret, D.; Lorente, N.P.F.

    We discuss the current state of integrating the Mutli Unit Spectroscopic Explorer (hereafter: MUSE) software pipeline (Weilbacher et al. 2006) into the Astro-WISE system (Valentijn et al. 2007a; Vriend et al. 2012). MUSE is a future integral-field spectrograph for the VLT, consisting of 24 Integral

  3. Astro-WISE interfaces : Scientific information system brought to the user

    NARCIS (Netherlands)

    Belikov, Andrey N.; Vriend, Willem-Jan; Sikkema, Gert

    From a simple text interface to a graphical user interfaces-Astro-WISE provides the user with a wide range of possibilities to interact with the information system according to the user's tasks and use cases. We describe a general approach to the interfacing of a scientific information system. We

  4. Making and Being Made: Wise Humanising Creativity in Interdisciplinary Early Years Arts Education

    Science.gov (United States)

    Chappell, Kerry Anne; Pender, Tamsin; Swinford, Elizabeth; Ford, Katherine

    2016-01-01

    This paper focuses on how wise humanising creativity (WHC) is manifested within early years interdisciplinary arts education. It draws on Arts Council-funded participatory research by Devon Carousel Project and University of Exeter's Graduate School of Education. It is grounded in previous AHRC-funded research, which conceptualised WHC in the face…

  5. Topographical investigation of changes in depth-wise proteoglycan distribution in rabbit femoral articular cartilage at 4 weeks after transection of the anterior cruciate ligament.

    Science.gov (United States)

    Arokoski, Mikko E A; Tiitu, Virpi; Jurvelin, Jukka S; Korhonen, Rami K; Fick, James M

    2015-09-01

    In this study, we explore topographical changes in proteoglycan distribution from femoral condylar cartilage in early osteoarthritis, acquired from both the lateral and medial condyles of anterior cruciate ligament transected (ACLT) and contralateral (CNTRL) rabbit knee joints, at 4 weeks post operation. Four sites across the cartilage surface in a parasagittal plane were defined across tissue sections taken from femoral condyles, and proteoglycan (PG) content was quantified using digital densitometry. The greatest depth-wise change in PG content due to an ACLT (compared to the CNTRL group) was observed anteriorly (site C) from the most weight-bearing location within the lateral compartment. In the medial compartment, the greatest change was observed in the most weight-bearing location (site B). The depth-wise changes in PG content were observed up to 48% and 28% depth from the tissue surface at these aforementioned sites, respectively (p < 0.05). The smallest depth-wise change in PG content was observed posteriorly (site A) from the most weight-bearing location within both femoral condyles (up to 20% and up to 5% depth from the tissue surface at lateral and medial compartments, respectively). This study gives further insight into how early cartilage deterioration progresses across the parasagittal plane of the femoral condyle. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  6. Handbook for evaluation studies in virtual reality

    DEFF Research Database (Denmark)

    Livatino, Salvatore; Koeffel, Christina

    2006-01-01

    Virtual reality (VR) applications are spreading and attract industries since VR technologies are becoming more affordable, powerful and robust. VR applications inherently call for human-computer interaction, which in turn calls for system and usability evaluations, typically through measurement...

  7. Pixel-wise estimation of noise statistics on iterative CT reconstruction from a single scan.

    Science.gov (United States)

    Wang, Tonghe; Zhu, Lei

    2017-07-01

    As iterative CT reconstruction continues to advance, the spatial distribution of noise standard deviation (STD) and accurate noise power spectrum (NPS) on the reconstructed CT images become important for method evaluation as well as optimization of algorithm parameters. Using a single CT scan, we propose a practical method for pixel-wise calculation of noise statistics on an iteratively reconstructed CT image, which enables accurate calculation of noise STD for each pixel and NPS. We first derive the noise propagation from measured projections to an iteratively reconstructed CT image provided that the projection noise is known. We then show that the model of noise propagation remains approximately unchanged for extra simulated noise added on the measured projections. To compute the noise STD map and the NPS map on an iteratively reconstructed CT image from a single scan, we first iteratively reconstruct the CT image from the measured projections using an existing reconstruction algorithm. The same measured projections are added by different sets (a total of 32 sets in our implementation) of projection noise simulated from an estimated projection noise model, and are then used to iteratively reconstruct different CT images. The calculations of the noise STD map and the NPS map are finally performed on the entire stack of these different reconstruction images. We evaluate our method on an anthropomorphic head phantom, and demonstrate the clinical utility on a set of head and neck patient CT data, using two iterative CT reconstruction algorithms: the penalized weighted least-square (PWLS) algorithm and the total-variation (TV) regularization. In the head phantom case, repeated scans are acquired to generate the ground truths of noise STD and NPS maps. Using only one single scan, the proposed method accurately calculates the noise STD maps with a root-mean-square error (RMSE) of less than 5HU. In the NPS map estimation, we compare the result of our proposed method with

  8. Choosing wisely: prevalence and correlates of low-value health care services in the United States.

    Science.gov (United States)

    Colla, Carrie H; Morden, Nancy E; Sequist, Thomas D; Schpero, William L; Rosenthal, Meredith B

    2015-02-01

    Specialty societies in the United States identified low-value tests and procedures that contribute to waste and poor health care quality via implementation of the American Board of Internal Medicine Foundation's Choosing Wisely initiative. To develop claims-based algorithms, to use them to estimate the prevalence of select Choosing Wisely services and to examine the demographic, health and health care system correlates of low-value care at a regional level. Using Medicare data from 2006 to 2011, we created claims-based algorithms to measure the prevalence of 11 Choosing Wisely-identified low-value services and examined geographic variation across hospital referral regions (HRRs). We created a composite low-value care score for each HRR and used linear regression to identify regional characteristics associated with more intense use of low-value services. Fee-for-service Medicare beneficiaries over age 65. Prevalence of selected Choosing Wisely low-value services. The national average annual prevalence of the selected Choosing Wisely low-value services ranged from 1.2% (upper urinary tract imaging in men with benign prostatic hyperplasia) to 46.5% (preoperative cardiac testing for low-risk, non-cardiac procedures). Prevalence across HRRs varied significantly. Regional characteristics associated with higher use of low-value services included greater overall per capita spending, a higher specialist to primary care ratio and higher proportion of minority beneficiaries. Identifying and measuring low-value health services is a prerequisite for improving quality and eliminating waste. Our findings suggest that the delivery of wasteful and potentially harmful services may be a fruitful area for further research and policy intervention for HRRs with higher per-capita spending. These findings should inform action by physicians, health systems, policymakers, payers and consumer educators to improve the value of health care by targeting services and areas with greater use of

  9. ["Deciding wisely together" - an initiative of the Association of the Scientific Medical Societies in Germany: Mission, methodology and application].

    Science.gov (United States)

    Nothacker, Monika; Kreienberg, Rolf; Kopp, Ina B

    2017-12-01

    The question of how to improve healthcare quality and the need for patient empowerment and shared decision-making has been the subject of political and scientific debate for years. In addition to various quality initiatives, "top lists" summarizing selected recommendations to increase awareness of overuse, spread by means of public campaigns, has become popular on the international level - known as the "Choosing Wisely" initiative. However, the trustworthiness of "top lists", their impact on patient-relevant outcomes, their role in and integration into the context of the various pre-existing approaches to improve healthcare quality and the effects of neglecting under- and misuse are not clear. On the other hand, "top lists" may provide new opportunities to improve awareness and dissemination of carefully selected recommendations based on high-quality guidelines. Therefore, the Association of Scientific Medical Societies in Germany (AWMF) has established an ad hoc commission to design a system-specific initiative. The commission has the task to clarify goals, methods of development and concepts for implementation and evaluation, to address concerns and to build upon specific existing resources - e. g., the established quality management system for guidelines in Germany. The key goals defined by the commission include the systematization of the dialogue between healthcare practitioners and patients and the promotion of ethically founded decision-making as an answer to an increasing economic orientation of the healthcare system. To ensure the methodological quality of specific recommendations, the commission has developed a manual. To the best of our knowledge, this manual is the first detailed method paper aiming to guide developers of "Choosing Wisely" recommendations. More than 20 German medical scientific societies have already addressed the subject of "top lists". Copyright © 2017. Published by Elsevier GmbH.

  10. A step-wise semi-distributed simulation approach to characterize a karst aquifer and to support dam construction in a data-scarce environment

    Science.gov (United States)

    Adinehvand, R.; Raeisi, E.; Hartmann, A.

    2017-11-01

    Karst systems provide significant volumes of drinking water for large parts of the world population. Due to chemical weathering, karst systems are characterized by strong heterogeneity resulting in a complex flow and storage behaviour. Presently available karst modelling strategies account for the karstic heterogeneity but often a lack of data limits their applicability in data-scarce regions. In this study, a step-wise simulation approach with a semi-distributed karst model is proposed to characterize a karst aquifer at a data-scarce region in Southwest Iran and to evaluate the leakage potential related to a future dam construction project at a river that cuts through the aquifer. Observed groundwater level time series were applied to calibrate and validate the model. In order to avoid over-parameterization, the karst aquifer was split into three sections down the hydraulic gradient. At each section, groundwater level observations were used to iteratively calibrate the model from the first to the last section. A spatial split-sample test and sensitivity analysis served to evaluate the prediction performance and the identifiability of the model parameters. Finally, simple scenarios of the river infiltration into the aquifer were applied to evaluate the leakage potential of the aquifer for future dam constructions. The spatial split-sample test showed that the semi-distributed model provided reliable predictions but prediction performance and parameter identifiability decreased from the first towards the last aquifer section, most probably due to increased aquifer complexity and propagation of uncertainty from the up-gradient model section. Using sensitivity analysis, we also show that parameter sensitivities increase significantly if parameter estimation was applied simultaneously to all three aquifer subsections. Using the model to assess the leakage potential indicated that, without further technical measures, the all river flow would be able infiltrate into the

  11. Designing Evaluations: A Study Examining Preferred Evaluation Designs of Educational Evaluators

    Science.gov (United States)

    Azzam, Tarek; Szanyi, Michael

    2011-01-01

    A sample of educational evaluators was asked to design an outcomes-focused evaluation of a school program that aims to improve the academic achievement and self-esteem of students. Evaluators provided detailed descriptions of their evaluation design and methodology in their responses. These descriptions were coded and analyzed to determine the…

  12. Preferences for public involvement in health service decisions: a comparison between best-worst scaling and trio-wise stated preference elicitation techniques.

    Science.gov (United States)

    Erdem, Seda; Campbell, Danny

    2017-12-01

    Stated preference elicitation techniques, such as discrete choice experiments and best-worst scaling, are now widely used in health research to explore the public's choices and preferences. In this paper, we propose an alternative stated preference elicitation technique, which we refer to as 'trio-wise'. We explain this new technique, its relative advantages, modeling framework, and how it compares to the best-worst scaling method. To better illustrate the differences and similarities, we utilize best-worst scaling Case 2, where individuals make best and worst (most and least) choices for the attribute levels that describe a single profile. We demonstrate this new preference elicitation technique using an empirical case study that explores preferences among the general public for ways to involve them in decisions concerning the health care system. Our findings show that the best-worst scaling and trio-wise preference elicitation techniques both retrieve similar preferences. However, the capability of our trio-wise method to provide additional information on the strength of rank preferences and its ability to accommodate indifferent preferences lead us to prefer it over the standard best-worst scaling technique.

  13. Students get wise about AIDS - The acceptability, feasibility and ...

    African Journals Online (AJOL)

    Objectives. The study assessed the acceptability and feasibility of an AIDS education programme for South African high-school students. Design, setting and sUbjects. A 'before-after' study was conducted in a suburban high school in Cape Town. All 232 standard 8 students were included, and were exposed to the ...

  14. Evaporation Kinetics of Organic Aerosols: Species-wise Measurements and Estimates

    Science.gov (United States)

    Zhang, H.; Worton, D. R.; Shen, S.; Nah, T.; Wilson, K. R.; Goldstein, A. H.

    2014-12-01

    A large fraction of atmospheric fine particulate matters (PM2.5) are organic aerosols (OA) that can form from primary emission (primary OA) or oxidation of more volatile organic compounds (secondary OA). Most OA are semi-volatile that can evaporate from particle phase to gas phase. OA evaporation strongly impacts aerosol mass loading, aerosol oxidation state, and aerosol properties in the atmosphere. In this study, we use four semi-volatile long-chain n-alkanes (n-octadecane, n-eicosane, n-docosane, and n-tetracosane) and α-pinene-derived OA as surrogates for primary and secondary OA, respectively. The evaporation of these OA components was examined in a flow reactor. Two soft ionization mass spectrometry techniques were used to measure evaporation kinetics of individual OA constituents: on-line direct analysis in real time-mass spectrometry (DART-MS) (used for secondary OA) and off-line two-dimensional gas chromatograph coupled to a high-resolution time-of-flight mass spectrometer (GC×GC/HTOF-MS) with vacuum ultraviolet (VUV) photoionization (used for primary OA). The semi-volatile n-alkanes can be oxidized in both phases, following different reaction schemes and leading to multigenerational oxygenated products with different isomeric distributions. Here the evaporation kinetic of primary OA surrogates was determined based on chemical analysis and kinetic simulations. The evaporation of α-pinene-derived OA was characterized based on the DART-MS mass spectra change upon heating. Results for both systems suggest slow evaporation compared to the gas-particle partitioning theory, especially when the OA are solid. The species-wise measurements using novel techniques provide insights into the detailed evaporation kinetics for atmospheric relevant systems.

  15. Ultrasound Small Vessel Imaging With Block-Wise Adaptive Local Clutter Filtering.

    Science.gov (United States)

    Song, Pengfei; Manduca, Armando; Trzasko, Joshua D; Chen, Shigao

    2017-01-01

    Robust clutter filtering is essential for ultrasound small vessel imaging. Eigen-based clutter filtering techniques have recently shown great improvement in clutter rejection over conventional clutter filters in small animals. However, for in vivo human imaging, eigen-based clutter filtering can be challenging due to the complex spatially-varying tissue and noise characteristics. To address this challenge, we present a novel block-wise adaptive singular value decomposition (SVD) based clutter filtering technique. The proposed method divides the global plane wave data into overlapped local spatial segments, within which tissue signals are assumed to be locally coherent and noise locally stationary. This, in turn, enables effective separation of tissue, blood and noise via SVD. For each block, the proposed method adaptively determines the singular value cutoff thresholds based on local data statistics. Processing results from each block are redundantly combined to improve both the signal-to-noise-ratio (SNR) and the contrast-to-noise-ratio (CNR) of the small vessel perfusion image. Experimental results show that the proposed method achieved more than two-fold increase in SNR and more than three-fold increase in CNR in dB scale over the conventional global SVD filtering technique for an in vivo human native kidney study. The proposed method also showed substantial improvement in suppression of the depth-dependent background noise and better rejection of near field tissue clutter. The effects of different processing block size and block overlap percentage were systematically investigated as well as the tradeoff between imaging quality and computational cost.

  16. Common and Privatized: Conditions for Wise Management of Matsutake Mushrooms in Northwest Yunnan Province, China

    Directory of Open Access Journals (Sweden)

    Xuefei Yang

    2009-12-01

    Full Text Available Since Hardin's (1968 paper on the "Tragedy of the Commons," property rights of common-pool resources have been a central concern for natural resource management scholars. Matsutake, a common-pool resource, is an economically important mushroom in several locations around the world. Driven by growing international demand over the last few decades, matsutake management is a relatively new practice both for local communities and government agencies. In Northwest Yunnan, China, one of the most productive areas for matsutake globally, numerous local practices and systems have emerged in the last two to three decades. In this study, we investigate the differences between management systems in eight communities and the factors associated with them. The methods used for field research included key-informant interviews, household surveys, and questionnaires. Three main management patterns were identified through use of statistical clustering based on indicators such as physical environment, resource characteristics, tenure arrangements, regulations and implementation, harvesting behavior, income, and market regulation. It was found that private access - the principal characteristic of which is the exclusive use of resources - results in more income at lower labor cost per household than either of the other open-access management patterns. Even though under the context of ongoing Second Forest Tenure Reform in China - in which collective forest privatization is the key task - application of private-access regimes is limited because of site conditions including physical, institutional, and market environments. Common-access management systems have advantages in terms of managing conflict and balancing equity needs. No matter the type of access right, the key issue for wise matsutake management is institutional. Locally rooted innovative strategies should be encouraged, and institutional capacity building should be carried out to support innovations in

  17. WMC Database Evaluation. Case Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Palounek, Andrea P. T [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-29

    The WMC Database is ultimately envisioned to hold a collection of experimental data, design information, and information from computational models. This project was a first attempt at using the Database to access experimental data and extract information from it. This evaluation shows that the Database concept is sound and robust, and that the Database, once fully populated, should remain eminently usable for future researchers.

  18. Study on segmented distribution for reliability evaluation

    Directory of Open Access Journals (Sweden)

    Huaiyuan Li

    2017-02-01

    Full Text Available In practice, the failure rate of most equipment exhibits different tendencies at different stages and even its failure rate curve behaves a multimodal trace during its life cycle. As a result, traditionally evaluating the reliability of equipment with a single model may lead to severer errors. However, if lifetime is divided into several different intervals according to the characteristics of its failure rate, piecewise fitting can more accurately approximate the failure rate of equipment. Therefore, in this paper, failure rate is regarded as a piecewise function, and two kinds of segmented distribution are put forward to evaluate reliability. In order to estimate parameters in the segmented reliability function, Bayesian estimation and maximum likelihood estimation (MLE of the segmented distribution are discussed in this paper. Since traditional information criterion is not suitable for the segmented distribution, an improved information criterion is proposed to test and evaluate the segmented reliability model in this paper. After a great deal of testing and verification, the segmented reliability model and its estimation methods presented in this paper are proven more efficient and accurate than the traditional non-segmented single model, especially when the change of the failure rate is time-phased or multimodal. The significant performance of the segmented reliability model in evaluating reliability of proximity sensors of leading-edge flap in civil aircraft indicates that the segmented distribution and its estimation method in this paper could be useful and accurate.

  19. Detecting phase separation of freeze-dried binary amorphous systems using pair-wise distribution function and multivariate data analysis

    DEFF Research Database (Denmark)

    Chieng, Norman; Trnka, Hjalte; Boetker, Johan

    2013-01-01

    The purpose of this study is to investigate the use of multivariate data analysis for powder X-ray diffraction-pair-wise distribution function (PXRD-PDF) data to detect phase separation in freeze-dried binary amorphous systems. Polymer-polymer and polymer-sugar binary systems at various ratios were...... freeze-dried. All samples were analyzed by PXRD, transformed to PDF and analyzed by principal component analysis (PCA). These results were validated by differential scanning calorimetry (DSC) through characterization of glass transition of the maximally freeze-concentrate solute (Tg'). Analysis of PXRD......-PDF data using PCA provides a more clear 'miscible' or 'phase separated' interpretation through the distribution pattern of samples on a score plot presentation compared to residual plot method. In a phase separated system, samples were found to be evenly distributed around the theoretical PDF profile...

  20. Wisdom from life's challenges: qualitative interviews with low- and moderate-income older adults who were nominated as being wise.

    Science.gov (United States)

    Choi, Namkee G; Landeros, Christina

    2011-01-01

    Previous wisdom research tended to focus on cognitive and intellectual aspects, highly educated professionals and/or prominent subjects, and wisdom as the outcome not process. In this study, based on in-depth interviews of 18 low- and moderate income older adults who were nominated as being wise by their aging-service providers, we explored the ways challenging life experiences and coping may have contributed to the development of their wisdom, their ideas/beliefs about the qualities of wisdom, and the ways they may be practicing wisdom in daily life. Their emphasis on interconnectedness and interdependence, forgiveness and patience, and gratitude appears to represent self-transcendental qualities of wisdom. Social work practice and research implications are discussed.

  1. An empirical examination of WISE/NEOWISE asteroid analysis and results

    Science.gov (United States)

    Myhrvold, Nathan

    2017-10-01

    Observations made by the WISE space telescope and subsequent analysis by the NEOWISE project represent the largest corpus of asteroid data to date, describing the diameter, albedo, and other properties of the ~164,000 asteroids in the collection. I present a critical reanalysis of the WISE observational data, and NEOWISE results published in numerous papers and in the JPL Planetary Data System (PDS). This analysis reveals shortcomings and a lack of clarity, both in the original analysis and in the presentation of results. The procedures used to generate NEOWISE results fall short of established thermal modelling standards. Rather than using a uniform protocol, 10 modelling methods were applied to 12 combinations of WISE band data. Over half the NEOWISE results are based on a single band of data. Most NEOWISE curve fits are poor quality, frequently missing many or all the data points. About 30% of the single-band results miss all the data; 43% of the results derived from the most common multiple-band combinations miss all the data in at least one band. The NEOWISE data processing procedures rely on inconsistent assumptions, and introduce bias by systematically discarding much of the original data. I show that error estimates for the WISE observational data have a true uncertainty factor of ~1.2 to 1.9 times larger than previously described, and that the error estimates do not fit a normal distribution. These issues call into question the validity of the NEOWISE Monte-Carlo error analysis. Comparing published NEOWISE diameters to published estimates using radar, occultation, or spacecraft measurements (ROS) reveals 150 for which the NEOWISE diameters were copied exactly from the ROS source. My findings show that the accuracy of diameter estimates for NEOWISE results depend heavily on the choice of data bands and model. Systematic errors in the diameter estimates are much larger than previously described. Systematic errors for diameters in the PDS range from -3% to

  2. Idioms: Wise as an Owl and Good as Gold.

    Science.gov (United States)

    McNeill, Joyce H.; Harper, Julia P.

    1991-01-01

    A technique is presented for teaching deaf students self-discipline along with useful idiomatic expressions. Idioms selected for study (such as "top dog,""in the doghouse,""sitting pretty," and "in hot water") are related to school rules, depicted on a bulletin board, and used to track classroom behavior.…

  3. Syndrome-wise diagnosis status of sexually transmitted infection ...

    African Journals Online (AJOL)

    problem, stigma and discrimination associated with the STDs, lack of interdepartmental coordination for studies, poor attendance of STD patients at the public clinics and academic institutions, and availability of limited diagnostic facilities, among others. This in-depth clinical research offers an important insight into the ...

  4. Adaptive Rule-Based Piece-Wise Regression Models for Estimating Regional Net Ecosystem Exchange in Grassland and Shrubland Ecoregions Using Regional and Flux Tower Data

    Science.gov (United States)

    Fosnight, E. A.; Wylie, B. K.; Zhang, L.

    2005-12-01

    The scientific understanding of the global carbon cycle requires quantitative documentation, monitoring, and projection of carbon stocks and fluxes at various scales across the landscape. The challenge is to develop predictive models using carbon flux towers at site-specific locations, and to extrapolate these models to landscapes and regions. We use remote sensing and national climate and soil databases within data-driven models to estimate carbon fluxes. To accommodate the study of coupled human-environmental relationships and their influences on carbon dynamics, a coherent suite of models is being developed for agricultural, wooded and wetland ecosystems within predominantly grassland and shrubland ecoregions. In previous work, we have mapped carbon fluxes in terms of Net Ecosystem Exchange (NEE), Gross Primary Production (GPP), and Respiration (Re) in the Northern Great Plains, the Sagebrush Steppes and the Kazakh Steppes at 1-km resolution and 10-day time steps. We now extend this work beyond fairly uniform ecological conditions to accommodate more complex spatial mixtures of ecological types within ecoregions. The models need to adapt to both the complexity of the environmental variables and the land cover patterns. Our rule-based models adapt to local climatic, soil and phenology through the definition of piece-wise regression models. A suite of such models is needed to capture the phenologic and climatic variability across the wide range of shrubland and grassland ecoregions that exist. The result is a multi-year time series of 1-km maps of carbon flux that are suitable for trend and anomaly analysis. We seek sensitive models that permit the effective study of localized carbon dynamics while avoiding over-fitting the available carbon flux tower measurement data. Two critical components of the project are (1) sensitivity and cross-validation studies to evaluate the internal consistencies of the models and (2) intercomparison studies to help isolate

  5. Countries three wise men: Sustainability, Innovation, and Competitiveness

    Directory of Open Access Journals (Sweden)

    Luis Miguel Fonseca

    2015-09-01

    Full Text Available Purpose: The studies on links between sustainability, innovation, and competitiveness have been mainly focused at organizational and business level. The purpose of this research is to investigate if there is a correlation between these three variables at country level. Using international well recognized rankings of countries sustainability, innovation, and competitiveness, correlation analysis was performed allowing for the conclusion that there are indeed high correlations (and possible relationships between the three variables at country level. Design/methodology/approach: Sustainability, innovation, and competitiveness literature were reviewed identifying a lack of studies examining these three variables at country level. Three major well recognized indexes were used to support the quantitative research: The World Economic Forum (2013 Sustainability-adjusted global competitiveness index, the Global Innovation Index (2014 issued by Cornell University, INSEAD, and WIPO and the IMD World Competitiveness Yearbook (2014. After confirming the distributions normality, Pearson correlation analysis was made with results showing high linear correlations between the three indexes. Findings: The results of the correlation analysis using Pearson correlation coefficient (all correlation coefficients are greater than 0.73 give a strong support to the conclusion that there is indeed a high correlation (and a possible relationship between social sustainability, innovation and competitiveness at country level. Research limitations/implications: Further research is advisable to better understand the factors that contribute to the presented results and to establish a global paradigm linking these three main constructs (social sustainability, innovation, and competitiveness. Some authors consider that these measurements are not fully supported (e.g. due to different countries standards, however, it is assumed these differing underlying methodological approaches

  6. Statistical design and evaluation of biomarker studies.

    Science.gov (United States)

    Dobbin, Kevin K

    2014-01-01

    We review biostatistical aspects of biomarker studies, including design and analysis issues, covering the range of settings required for translational research-from early exploratory studies through clinical trials.

  7. Evaluating Humane Education: The Jefferson County Study.

    Science.gov (United States)

    Fitzgerald, Thomas A., Jr.

    1981-01-01

    Describes a study which analyzes the impact of three different humane education treatments, all examples of traditional programs taught by local humane societies to fifth- and sixth-grade students. Results are compared with similar studies previously conducted. (CS)

  8. Evaluation of Social Studies Curriculum on Compassion ...

    African Journals Online (AJOL)

    NCE III social studies students exhibited greater level of moderate to high compassion as a result of exposure to social studies curriculum. Based on these findings, the researcher made some recommendations such as inclusion of cultural values that encourage compassion into social studies curriculum among others.

  9. Time-wise change in neck pain in response to rehabilitation with specific resistance training

    DEFF Research Database (Denmark)

    Zebis, Mette Kreutzfeldt; Andersen, Christoffer H; Sundstrup, Emil

    2014-01-01

    Purpose To determine the time-wise effect of specific resistance training on neck pain among industrial technicians with frequent neck pain symptoms. Methods Secondary analysis of a parallel-group cluster randomized controlled trial of 20 weeks performed at two large industrial production units...... in Copenhagen, Denmark. Women with neck pain >30 mm VAS (N = 131) were included in the present analysis. The training group (N = 77) performed specific resistance training for the neck/shoulder muscles three times a week, and the control group (N = 54) received advice to stay active. Participants of both groups...... to 20). The time-wise change in pain showed three phases; a rapid decrease in the training group compared with the control group during the initial 7 weeks, a slower decrease in pain during the following weeks (week 8–15), and a plateau during the last weeks (week 16–20). Adherence to training followed...

  10. Raising the Albedo of 2010 GY6: Fitting ATPM to Wise Data

    Science.gov (United States)

    Wooden, D. H.; Rozitis, B. D.; Jefferson, J. D.; Nelson, T. W.; Dotson, J. L.

    2017-01-01

    Near-Earth Asteroid 462775 (2010 GY6) is in the Apollo orbit-family with a 1.46 year orbital period. 2010 GY6 was measured by WISE and fitted with NEATM, yielding NEATM model parameters of D=1.1 km, pv=0.028 and eta=2.3.The NEATM-derived geometric albedo of 2010 GY6 is lower than the surface of comet 67P/C-G. The eta value is considerably higher than typical for its phase angle of 33 deg, indicating a cooler surface due to non-zero thermal inertia and/or surface roughness are important. If the thermal inertia and surface roughness are constrained by fitting the Advanced Thermophysical Model (ATPM) to the WISE data, what would the resulting geometric albedo? We find pv=0.06-0.08, in the same range as B- or C-type NEAs like Bennu or JU3.

  11. Bitmap-Wise Wireless M-Bus Coordination for Sustainable Real Time Energy Management

    Directory of Open Access Journals (Sweden)

    Kwang-il Hwang

    2014-07-01

    Full Text Available Even though WM-Bus is being considered to be the most promising network protocol for smart metering, it is not suitable for a sustainable real-time home energy management system (HEMS, which requires higher reliability and longer lifetime despite real time bi-directional communications. Therefore, in this paper we propose a Bitmap-wise WM-Bus (BWM-Bus, coping well with sustainable real-time HEMS. In particular, the proposed scheme addresses the several problems in WM-Bus for HEMS by introducing novel functions: asynchronous meter trigger, adaptive slot scheduling, and bitmap-wise retransmission request. Through experiments, we demonstrate that BWM-Bus guarantees higher data success ratio with lower data aggregation time, as well as longer lifetime than WM-Bus standard.

  12. GEO Collisional Risk Assessment Based on Analysis of NASA-WISE Data and Modeling

    Science.gov (United States)

    2015-10-18

    instrument captured imagery that contained unresolved measurements of space debris . Specifically, the NASA-WISE instrument captured unresolved...measurements of space debris in the GEO belt. The Air Force Research Lab created a debris catalog that includes over 2,000 measurements of previously...conjunction flux between geostationary satellites and debris using the space catalog. The algorithm and software for CAOSD was developed to process all

  13. New Resource-Wise Planning Strategies for Smart Urban-Rural Development in Finland

    Directory of Open Access Journals (Sweden)

    Emilia Rönkkö

    2017-02-01

    Full Text Available This article discusses the opportunities and challenges for resource-wise development strategies in regional planning. Spatial planning integrates the key aspects, transportation, housing, and food production which are, on many occasions, stated as the most significant consumption factors causing environmental impacts. In light of the challenges that regions are currently facing in Finland, we are drawing attention to the role of strategic spatial planning as demand-responsive resource management, a theme which is still inadequately addressed within regional development and planning in Finland. In many other fields of society, innovative data-based products and demand- and user-driven services are considered important sources of success in the future. Such strategies combine different types of service providers, like deliveries for groceries or restaurant meals, mobile healthcare services, or public transport with on-demand services. We highlight the fact that a regionally large and sparsely populated country, such as Finland, cannot achieve success solely through centralisation. Instead, smart networking, co-creation, and innovative cyber-physical solutions are vital for the utilisation of the entire country’s resource potentiality. In conclusion, we underpin the need for a framework, which would offer a strategic support scheme for resource-wise development, resource optimization, and closure of yield gaps. In our view it is necessary to begin to envision, strategise, and develop user- and demand-responsive development strategies with a specific aim for sustainable, resource-wise ways of life in northern regions, also outside the growing urban centres, and innovate solutions that help individuals, communities, and the whole society to renew and manage resources wisely.

  14. On IA-automorphisms that fix the centre element-wise

    Indian Academy of Sciences (India)

    Abstract. Let G be a group. An automorphism of G is called an IA-automorphism if it induces the identity mapping on G/γ2(G), where γ2(G) is the commutator sub- group of G. Let IAz(G) be the group of those IA-automorphisms, which fix the centre element-wise and let Autcent(G) be the group of central automorphisms, the ...

  15. Food for thought: interpreting the parable of the loyal and wise slave ...

    African Journals Online (AJOL)

    The parable of the loyal and wise slave appears in Q 12:42-46 (Matt. 24:45-51; Luke 12:42-46). I have argued elsewhere that verses 45-46 were added to verses 42-44 by Q's main redactor. If so, only Q 12:42-44 originally appeared in Kloppenborg's formative stratum, or Q1. The purpose of the present article is to ascertain ...

  16. On IA-automorphisms that fix the centre element-wise

    Indian Academy of Sciences (India)

    Let be a group. An automorphism of is called an I A -automorphism if it induces the identity mapping on G / 2 ( G ) , where 2 ( G ) is the commutator sub-group of . Let I A z ( G ) be the group of those I A -automorphisms, which fix the centre element-wise and let Autcent ( G ) be the group of central automorphisms, ...

  17. Brigadier General Henry A. Wise, C.S.A. and the Western Virginia Campaign of 1861

    Science.gov (United States)

    1980-06-06

    referred to USACGSCv ATTN: ATZL.SWD.GD9 Fort Leavenworthp KS 66027e DISTRIBUTION STATEMENT ACCESSION FOR "UNANNOUNCED ’ TIC JUSTIFICATION ELECTE...western Virginia represent- ed an access route for the invasion of the North or South by military forces stationed within the region. The in- dustrialized...Stutler, West Virginia, 65-66. 33Ibid., 65. 67 and denied the Union forces use of the Kanawha River for transportaion and logistics. Instead, Wise

  18. TermWise: Leveraging Big Data for Terminological Support in Legal Translation

    OpenAIRE

    Heylen, Kris; Bond, Stephen; De Hertog, Dirk; Kockaert, Hendrik; Steurs, Frieda; Vulic, Ivan

    2014-01-01

    International audience; Increasingly, large bilingual document collections are being made available online, especially in the legal domain. This type of Big Data is a valuable resource that specialized translators exploit to search for informative examples of how domain-specific expressions should be translated. However, general purpose search engines are not optimized to retrieve previous translations that are maximally relevant to a translator. In this paper, we report on the TermWise proje...

  19. DISCOVERY OF THE Y1 DWARF WISE J064723.23–623235.5

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, J. Davy; Gelino, Christopher R.; Beichman, Charles A.; Mace, Gregory N. [Infrared Processing and Analysis Center, MS 100-22, California Institute of Technology, Pasadena, CA 91125 (United States); Cushing, Michael C.; Schneider, Adam [Department of Physics and Astronomy, MS 111, University of Toledo, 2801 West Bancroft Street, Toledo, OH 43606-3328 (United States); Tinney, C. G. [School of Physics, University of New South Wales, Sydney, NSW 2052 (Australia); Faherty, Jacqueline K., E-mail: davy@ipac.caltech.edu [Department of Astronomy, University of Chile, Camino El Observatorio 1515, Casilla 36-D Santiago (Chile)

    2013-10-20

    We present the discovery of a very cold, very low mass, nearby brown dwarf using data from the NASA Wide-field Infrared Survey Explorer (WISE). The object, WISE J064723.23–623235.5, has a very red WISE color of W1–W2 > 3.77 mag and a very red Spitzer Space Telescope color of ch1–ch2 = 2.82 ± 0.09 mag. In J{sub MKO} –ch2 color (7.58 ± 0.27 mag) it is one of the two or three reddest brown dwarfs known. Our grism spectrum from the Hubble Space Telescope (HST) confirms it to be the seventeenth Y dwarf discovered, and its spectral type of Y1 ± 0.5 makes it one of the four latest-type Y dwarfs classified. Astrometric imaging from Spitzer and HST, combined with data from WISE, provides a preliminary parallax of π = 115 ± 12 mas (d = 8.7 ± 0.9 pc) and proper motion of μ = 387 ± 25 mas yr{sup –1} based on 2.5 yr of monitoring. The spectrum implies a blue J–H color, for which model atmosphere calculations suggest a relatively low surface gravity. The best fit to these models indicates an effective temperature of 350-400 K and a mass of ∼5-30 M{sub Jup}. Kinematic analysis hints that this object may belong to the Columba moving group, which would support an age of ∼30 Myr and thus an even lower mass of <2 M{sub Jup}, but verification would require a radial velocity measurement not currently possible for a J = 22.7 mag brown dwarf.

  20. PTM Along Track Algorithm to Maintain Spacing During Same Direction Pair-Wise Trajectory Management Operations

    Science.gov (United States)

    Carreno, Victor A.

    2015-01-01

    Pair-wise Trajectory Management (PTM) is a cockpit based delegated responsibility separation standard. When an air traffic service provider gives a PTM clearance to an aircraft and the flight crew accepts the clearance, the flight crew will maintain spacing and separation from a designated aircraft. A PTM along track algorithm will receive state information from the designated aircraft and from the own ship to produce speed guidance for the flight crew to maintain spacing and separation

  1. Study of in vitro methods to evaluate immunosuppression

    NARCIS (Netherlands)

    Carfi', M.

    2010-01-01

    The immune system is one important target of xenobiotic toxicity. In fact, immunotoxicity evaluation is becoming a growing concern for international regulatory authorities. At present, immunotoxicity of chemicals is evaluated through standard toxicity studies (STS) on laboratory animals. European

  2. Evaluation of multi-outcome longitudinal studies

    DEFF Research Database (Denmark)

    Jensen, Signe Marie; Pipper, Christian Bressen; Ritz, Christian

    2015-01-01

    conservative conclusions. We propose an alternative approach for multiplicity adjustment that incorporates dependence between outcomes, resulting in an appreciably less conservative evaluation. The ability of the proposed method to control the familywise error rate is evaluated in a simulation study...

  3. [Choosing wisely: the Top 5 list of the Italian Association of Hospital Cardiologists (ANMCO)].

    Science.gov (United States)

    Bobbio, Marco; Abrignani, Maurizio G; Caldarola, Pasquale; Casolo, Giancarlo; Fattirolli, Francesco; Gabrielli, Domenico; Grimaldi, Massimo; Mazzotta, Gianfranco; Roncon, Loris; Tozzi, Quinto; Vallebona, Alessandro

    2014-04-01

    In recent years, a progressive increase in the number of medical diagnostic and interventional procedures has been observed, namely in cardiology. A significant proportion of them appear inappropriate, i.e. potentially redundant, harmful, costly, and useless. Recently, the document Medical Professionalism in the New Millennium: A Physician Charter, the American Board of Internal Medicine (ABIM) Foundation Putting the Charter into Practice program, JAMA's Less Is More and BMJ's Too Much Medicine series, and the American College of Physicians' High-Value, Cost-Conscious Care initiatives, have all begun to provide direction for physicians to address pervasive overuse in health care. In 2010, the Brody's proposal to scientific societies to indicate the five medical procedures at high inappropriateness risk inspired the widely publicized ABIM Foundation's Choosing Wisely campaign. As part of Choosing Wisely, each participating specialty society has created lists of Things Physicians and Patients Should Question that provide specific, evidence-based recommendations physicians and patients should discuss to help make wise decisions about the most appropriate individual care. In Italy, Slow Medicine launched the analogue campaign Fare di più non significa fare meglio. The Italian Association of Hospital Cardiologists (ANMCO) endorsed the initiative by recognizing the need to optimize available resources, reduce costs and avoid unnecessary cardiovascular assessments, thereby enhancing the more efficient care delivery models. An ad hoc ANMCO Working Group prepared a list of five cardiac procedures that seem inappropriate for routine use in our country and, after an internal revision procedure, these are presented here.

  4. Evidence-based guidelines for the wise use of computers by children: physical development guidelines.

    Science.gov (United States)

    Straker, L; Maslen, B; Burgess-Limerick, R; Johnson, P; Dennerlein, J

    2010-04-01

    Computer use by children is common and there is concern over the potential impact of this exposure on child physical development. Recently principles for child-specific evidence-based guidelines for wise use of computers have been published and these included one concerning the facilitation of appropriate physical development. This paper reviews the evidence and presents detailed guidelines for this principle. The guidelines include encouraging a mix of sedentary and whole body movement tasks, encouraging reasonable postures during computing tasks through workstation, chair, desk, display and input device selection and adjustment and special issues regarding notebook computer use and carriage, computing skills and responding to discomfort. The evidence limitations highlight opportunities for future research. The guidelines themselves can inform parents and teachers, equipment designers and suppliers and form the basis of content for teaching children the wise use of computers. STATEMENT OF RELEVANCE: Many children use computers and computer-use habits formed in childhood may track into adulthood. Therefore child-computer interaction needs to be carefully managed. These guidelines inform those responsible for children to assist in the wise use of computers.

  5. WISE: Automated support for software project management and measurement. M.S. Thesis

    Science.gov (United States)

    Ramakrishnan, Sudhakar

    1995-01-01

    One important aspect of software development and IV&V is measurement. Unless a software development effort is measured in some way, it is difficult to judge the effectiveness of current efforts and predict future performances. Collection of metrics and adherence to a process are difficult tasks in a software project. Change activity is a powerful indicator of project status. Automated systems that can handle change requests, issues, and other process documents provide an excellent platform for tracking the status of the project. A World Wide Web based architecture is developed for (a) making metrics collection an implicit part of the software process, (b) providing metric analysis dynamically, (c) supporting automated tools that can complement current practices of in-process improvement, and (d) overcoming geographical barrier. An operational system (WISE) instantiates this architecture allowing for the improvement of software process in a realistic environment. The tool tracks issues in software development process, provides informal communication between the users with different roles, supports to-do lists (TDL), and helps in software process improvement. WISE minimizes the time devoted to metrics collection, analysis, and captures software change data. Automated tools like WISE focus on understanding and managing the software process. The goal is improvement through measurement.

  6. Connectome-scale group-wise consistent resting-state network analysis in autism spectrum disorder

    Directory of Open Access Journals (Sweden)

    Yu Zhao

    2016-01-01

    Full Text Available Understanding the organizational architecture of human brain function and its alteration patterns in diseased brains such as Autism Spectrum Disorder (ASD patients are of great interests. In-vivo functional magnetic resonance imaging (fMRI offers a unique window to investigate the mechanism of brain function and to identify functional network components of the human brain. Previously, we have shown that multiple concurrent functional networks can be derived from fMRI signals using whole-brain sparse representation. Yet it is still an open question to derive group-wise consistent networks featured in ASD patients and controls. Here we proposed an effective volumetric network descriptor, named connectivity map, to compactly describe spatial patterns of brain network maps and implemented a fast framework in Apache Spark environment that can effectively identify group-wise consistent networks in big fMRI dataset. Our experiment results identified 144 group-wisely common intrinsic connectivity networks (ICNs shared between ASD patients and healthy control subjects, where some ICNs are substantially different between the two groups. Moreover, further analysis on the functional connectivity and spatial overlap between these 144 common ICNs reveals connectomics signatures characterizing ASD patients and controls. In particular, the computing time of our Spark-enabled functional connectomics framework is significantly reduced from 240 hours (C++ code, single core to 20 hours, exhibiting a great potential to handle fMRI big data in the future.

  7. WiseEye: Next Generation Expandable and Programmable Camera Trap Platform for Wildlife Research.

    Directory of Open Access Journals (Sweden)

    Sajid Nazir

    Full Text Available The widespread availability of relatively cheap, reliable and easy to use digital camera traps has led to their extensive use for wildlife research, monitoring and public outreach. Users of these units are, however, often frustrated by the limited options for controlling camera functions, the generation of large numbers of images, and the lack of flexibility to suit different research environments and questions. We describe the development of a user-customisable open source camera trap platform named 'WiseEye', designed to provide flexible camera trap technology for wildlife researchers. The novel platform is based on a Raspberry Pi single-board computer and compatible peripherals that allow the user to control its functions and performance. We introduce the concept of confirmatory sensing, in which the Passive Infrared triggering is confirmed through other modalities (i.e. radar, pixel change to reduce the occurrence of false positives images. This concept, together with user-definable metadata, aided identification of spurious images and greatly reduced post-collection processing time. When tested against a commercial camera trap, WiseEye was found to reduce the incidence of false positive images and false negatives across a range of test conditions. WiseEye represents a step-change in camera trap functionality, greatly increasing the value of this technology for wildlife research and conservation management.

  8. WiseEye: Next Generation Expandable and Programmable Camera Trap Platform for Wildlife Research.

    Science.gov (United States)

    Nazir, Sajid; Newey, Scott; Irvine, R Justin; Verdicchio, Fabio; Davidson, Paul; Fairhurst, Gorry; Wal, René van der

    2017-01-01

    The widespread availability of relatively cheap, reliable and easy to use digital camera traps has led to their extensive use for wildlife research, monitoring and public outreach. Users of these units are, however, often frustrated by the limited options for controlling camera functions, the generation of large numbers of images, and the lack of flexibility to suit different research environments and questions. We describe the development of a user-customisable open source camera trap platform named 'WiseEye', designed to provide flexible camera trap technology for wildlife researchers. The novel platform is based on a Raspberry Pi single-board computer and compatible peripherals that allow the user to control its functions and performance. We introduce the concept of confirmatory sensing, in which the Passive Infrared triggering is confirmed through other modalities (i.e. radar, pixel change) to reduce the occurrence of false positives images. This concept, together with user-definable metadata, aided identification of spurious images and greatly reduced post-collection processing time. When tested against a commercial camera trap, WiseEye was found to reduce the incidence of false positive images and false negatives across a range of test conditions. WiseEye represents a step-change in camera trap functionality, greatly increasing the value of this technology for wildlife research and conservation management.

  9. WISE/NEOWISE OBSERVATIONS OF ACTIVE BODIES IN THE MAIN BELT

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, James M.; Mainzer, A. K.; Masiero, Joseph R.; Blauvelt, Erin K.; Cherry, De' Andre [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, MS 183-401, Pasadena, CA 91109 (United States); Grav, Tommy [Planetary Science Institute, 1700 East Fort Lowell, Suite 106, Tucson, AZ 85719-2395 (United States); Walker, Russell G. [Monterey Institute for Research in Astronomy, 200 Eighth Street, Marina, CA 93933 (United States); McMillan, Robert S.; Scotti, James V. [Lunar and Planetary Laboratory, University of Arizona, 1629 East University Boulevard, Kuiper Space Science Building 92, Tucson, AZ 85721-0092 (United States); Fernandez, Yan R.; Kramer, Emily [Department of Physics, University of Central Florida, 4000 Central Florida Boulevard, P.S. Building, Orlando, FL 32816-2385 (United States); Meech, Karen J.; Tholen, David J.; Riesen, Timm; Urban, Laurie; Khayat, Alain [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Manoa, HI 96822 (United States); Lisse, Carey M. [Applied Physics Laboratory, Johns Hopkins University, 11100 Johns Hopkins Road, Laurel, MD 20723-6099 (United States); Cutri, Roc M.; Dailey, John W.; Pearman, George, E-mail: bauer@scn.jpl.nasa.gov [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Collaboration: WISE Team; and others

    2012-03-01

    We report results based on mid-infrared photometry of five active main belt objects (AMBOs) detected by the Wide-field Infrared Survey Explorer (WISE) spacecraft. Four of these bodies, P/2010 R2 (La Sagra), 133P/Elst-Pizarro, (596) Scheila, and 176P/LINEAR, showed no signs of activity at the time of the observations, allowing the WISE detections to place firm constraints on their diameters and albedos. Geometric albedos were in the range of a few percent, and on the order of other measured comet nuclei. P/2010 A2 was observed on 2010 April 2-3, three months after its peak activity. Photometry of the coma at 12 and 22 {mu}m combined with ground-based visible-wavelength measurements provides constraints on the dust particle mass distribution (PMD), dlog n/dlog m, yielding power-law slope values of {alpha} = -0.5 {+-} 0.1. This PMD is considerably more shallow than that found for other comets, in particular inbound particle fluence during the Stardust encounter of comet 81P/Wild 2. It is similar to the PMD seen for 9P/Tempel 1 in the immediate aftermath of the Deep Impact experiment. Upper limits for CO{sub 2} and CO production are also provided for each AMBO and compared with revised production numbers for WISE observations of 103P/Hartley 2.

  10. Discovery of the young L dwarf wise J174102.78-464225.5

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Adam C.; Cushing, Michael C. [Department of Physics and Astronomy, University of Toledo, 2801 West Bancroft Street, Toledo, OH 43606 (United States); Kirkpatrick, J. Davy; Mace, Gregory N.; Gelino, Christopher R.; Fajardo-Acosta, Sergio [Infrared Processing and Analysis Center, MS 100-22, California Institute of Technology, Pasadena, CA 91125 (United States); Faherty, Jacqueline K. [Department of Astronomy, University of Chile, Camino El Observatorio 1515, Casilla 36-D, Santiago (Chile); Sheppard, Scott S., E-mail: Adam.Schneider@Utoledo.edu [Department of Terrestrial Magnetism, Carnegie Institution of Washington, 5241 Broad Branch Road NW, Washington, DC 20015 (United States)

    2014-02-01

    We report the discovery of the L dwarf WISE J174102.78–464225.5, which was discovered as part of a search for nearby L dwarfs using the Wide-field Infrared Survey Explorer (WISE). The distinct triangular peak of the H-band portion of its near-infrared spectrum and its red near-infrared colors (J – K{sub S} = 2.35 ± 0.08 mag) are indicative of a young age. Via comparison to spectral standards and other red L dwarfs, we estimate a near-infrared spectral type of L7 ± 2 (pec). From a comparison to spectral and low-mass evolutionary models, we determine self-consistent effective temperature, log g, age, and mass values of 1450 ± 100 K, 4.0 ± 0.25 (cm s{sup –2}), 10-100 Myr, and 4-21 M {sub Jup}, respectively. With an estimated distance of 10-30 pc, we explore the possibility that WISE J174102.78–464225.5 belongs to one of the young nearby moving groups via a kinematic analysis and we find potential membership in the β Pictoris or AB Doradus associations. A trigonometric parallax measurement and a precise radial velocity can help to secure its membership in either of these groups.

  11. Relevance and Methodological Adequacy: A Study of Evaluation Reports.

    Science.gov (United States)

    Nevo, David; Friedman, Etel

    The relationship among various characteristics of evaluation studies and their overall quality was studied using all of the evaluation studies (N=366) conducted in Israel over 30 years on special projects for disadvantaged students at the elementary school level. The following variables were defined to describe each study: (1) evaluation…

  12. Study design issues in evaluating immune biomarkers.

    Science.gov (United States)

    Bosch, Ronald J; Zhang, Xinyan; Sandler, Netanya G

    2013-03-01

    The dramatic increase in the number and type of immune biomarkers that can be measured, particularly those assessing immune activation, has led to numerous investigations in HIV-infected individuals to explore pathogenesis and to assess therapeutic interventions that aim to attenuate immune activation. An overview is provided on study designs and related statistical and operational issues relevant to these investigations. Cohort studies and nested case-control studies within these cohorts have identified multiple biomarkers that are associated with an increased risk of disease. Early-stage clinical trials of therapies to address these risks in HIV-infected individuals with viral suppression on antiretroviral therapy are a substantial focus of current HIV research. Appropriate study design is essential in biomarker research.

  13. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... is not sufficiently mature. Laboratory-based evaluations have also been shown to have insufficient external validity. Simulation studies seem to be a way to bridge this gap. The aim of this study was to evaluate, using a simulation methodology, the impact of a new prototype of an electronic medication management...

  14. Vibroacoustic test plan evaluation: Parameter variation study

    Science.gov (United States)

    Stahle, C. V.; Gongloef, H. R.

    1976-01-01

    Statistical decision models are shown to provide a viable method of evaluating the cost effectiveness of alternate vibroacoustic test plans and the associated test levels. The methodology developed provides a major step toward the development of a realistic tool to quantitatively tailor test programs to specific payloads. Testing is considered at the no test, component, subassembly, or system level of assembly. Component redundancy and partial loss of flight data are considered. Most and probabilistic costs are considered, and incipient failures resulting from ground tests are treated. Optimums defining both component and assembly test levels are indicated for the modified test plans considered. modeling simplifications must be considered in interpreting the results relative to a particular payload. New parameters introduced were a no test option, flight by flight failure probabilities, and a cost to design components for higher vibration requirements. Parameters varied were the shuttle payload bay internal acoustic environment, the STS launch cost, the component retest/repair cost, and the amount of redundancy in the housekeeping section of the payload reliability model.

  15. STUDIES AND EVALUATION OF COMPRESSED MICROSPHERES

    Directory of Open Access Journals (Sweden)

    Idris Mohamed El-Mahdi

    2016-05-01

    Full Text Available This work was aimed at the use of dissolution testing and similarity factor to assess the level of damage taken by active drug microspheres during compression in tablet dosage form. To achieve that, combinations of suitable excipients were used to protect drug microspheres during compression. The excipients were used in the form of powders, granules or placebo pellets prepared by extrusion-spheronization technology. The excipients were evaluated alone, in combinations and post-compression into compacts.  Preliminary experiments included density, hardness, friability and disintegration on all of the selected excipients. Based on such experiments it was found that the flowability of combination powders was more acceptable than individual excipients. Two combinations of microcrystalline -starch and microcrystalline cellulose -calcium carbonate granules were selected to be compressed with active ketoprofen pellets. In all the combinations used there was a significant amount of damage to drug pellets.  The kinetics of drug release appears to follow the zero-order rate and the rate remained unchanged even when a significant degree of damage to pellets occur. It was found that a high level of excipients is required in order to prepare microspheres as a rapid disintegrating tablet. Citation DOI: 10.21502/limuj.002.01.2016  LIMUJ is licensed under a Creative Commons Attribution 4.0 International License

  16. Benzodiazepine and sedative-hypnotic use among older seriously Ill veterans: choosing wisely?

    Science.gov (United States)

    Garrido, Melissa M; Prigerson, Holly G; Penrod, Joan D; Jones, Shatice C; Boockvar, Kenneth S

    2014-11-01

    The 2014 American Geriatrics Society's Choosing Wisely list cautions against the use of any benzodiazepines or other sedative-hypnotics (BSHs) as initial treatments for agitation, insomnia, or delirium in older adults. Because these symptoms are prevalent among hospitalized patients, seriously ill older adults are at risk of receiving these potentially inappropriate medications. The objectives of this study were to understand the extent to which potentially inappropriate BSHs are being used in hospitalized, seriously ill, older veterans and to understand what clinical and sociodemographic characteristics are associated with potentially inappropriate BSH use. We reviewed medical records of 222 veterans aged ≥65 years who were hospitalized in an acute care facility in the New York-New Jersey metropolitan region in fiscal years 2009 and 2010. Veterans had diagnoses of advanced cancer, chronic obstructive pulmonary disease, congestive heart failure, and/or HIV/AIDS and received inpatient palliative care. Associations among potentially inappropriate BSH use (BSHs for indications other than alcohol withdrawal and current generalized anxiety disorder or one-time use before a medical procedure) and clinical and sociodemographic characteristics were examined with multivariable logistic regression. One-fifth of the sample was prescribed a potentially inappropriate BSH during the index hospitalization during the study period (n = 47). The most commonly prescribed potentially inappropriate medications were zolpidem (n = 26 [11.7%]) and lorazepam (n = 19 [8.9%]). Hispanic ethnicity was significantly associated with prescription of potentially inappropriate BSHs among the entire sample (adjusted odds ratio [AOR] = 3.79; 95% CI, 1.32-10.88) and among patients who survived until discharge (n = 164; AOR = 5.28; 95% CI, 1.64-17.07). Among patients who survived until discharge, black patients were less likely to be prescribed potentially inappropriate BSHs than white patients (AOR

  17. Step-wise and punctuated genome evolution drive phenotype changes of tumor cells

    Energy Technology Data Exchange (ETDEWEB)

    Stepanenko, Aleksei, E-mail: a.a.stepanenko@gmail.com [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine); Andreieva, Svitlana; Korets, Kateryna; Mykytenko, Dmytro [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine); Huleyuk, Nataliya [Institute of Hereditary Pathology, National Academy of Medical Sciences of Ukraine, Lviv 79008 (Ukraine); Vassetzky, Yegor [CNRS UMR8126, Université Paris-Sud 11, Institut de Cancérologie Gustave Roussy, Villejuif 94805 (France); Kavsan, Vadym [Department of Biosynthesis of Nucleic Acids, Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv 03680 (Ukraine)

    2015-01-15

    Highlights: • There are the step-wise continuous and punctuated phases of cancer genome evolution. • The system stresses during the different phases may lead to very different responses. • Stable transfection of an empty vector can result in genome and phenotype changes. • Functions of a (trans)gene can be opposite/versatile in cells with different genomes. • Contextually, temozolomide can both promote and suppress tumor cell aggressiveness. - Abstract: The pattern of genome evolution can be divided into two phases: the step-wise continuous phase (step-wise clonal evolution, stable dominant clonal chromosome aberrations (CCAs), and low frequency of non-CCAs, NCCAs) and punctuated phase (marked by elevated NCCAs and transitional CCAs). Depending on the phase, system stresses (the diverse CIN promoting factors) may lead to the very different phenotype responses. To address the contribution of chromosome instability (CIN) to phenotype changes of tumor cells, we characterized CCAs/NCCAs of HeLa and HEK293 cells, and their derivatives after genotoxic stresses (a stable plasmid transfection, ectopic expression of cancer-associated CHI3L1 gene or treatment with temozolomide) by conventional cytogenetics, copy number alterations (CNAs) by array comparative genome hybridization, and phenotype changes by cell viability and soft agar assays. Transfection of either the empty vector pcDNA3.1 or pcDNA3.1-CHI3L1 into 293 cells initiated the punctuated genome changes. In contrast, HeLa-CHI3L1 cells demonstrated the step-wise genome changes. Increased CIN correlated with lower viability of 293-pcDNA3.1 cells but higher colony formation efficiency (CFE). Artificial CHI3L1 production in 293-CHI3L1 cells increased viability and further contributed to CFE. The opposite growth characteristics of 293-CHI3L1 and HeLa-CHI3L1 cells were revealed. The effect and function of a (trans)gene can be opposite and versatile in cells with different genetic network, which is defined by

  18. Design issues for evaluating seedling exposure studies.

    Science.gov (United States)

    E. Charles Peterson; A. Robert. Mickler

    1993-01-01

    Tree seedling studies, covering a wide range of experimental conditions in pollutant treatment, species, facilities, and exposure regimes, have become commonplace in forestry research for assessing the actual and potential environmental effects of air pollutants on forest ecosystems. While assuring a wide breadth of scientific information, sufficient consideration has...

  19. PeerWise provides significant academic benefits to biological science students across diverse learning tasks, but with minimal instructor intervention.

    Science.gov (United States)

    McQueen, H A; Shields, C; Finnegan, D J; Higham, J; Simmen, M W

    2014-01-01

    We demonstrate that student engagement with PeerWise, an online tool that allows students to author and answer multiple-choice questions (MCQs), is associated with enhanced academic performance across diverse assessment types on a second year Genetics course. Benefits were consistent over three course deliveries, with differential benefits bestowed on groups of different prior ability. A rating scheme, to assess the educational quality of students' questions, is presented and demonstrates that our students are able intuitively to make such quality assessments, and that the process of authoring high quality questions alone does not explain the academic benefits. We further test the benefits of providing additional PeerWise support and conclude that PeerWise works efficiently with minimal intervention, and can be reliably assessed using automatically generated PeerWise scores. Copyright © 2014 The International Union of Biochemistry and Molecular Biology.

  20. Student Evaluation of Teaching: A Case Study from School of ...

    African Journals Online (AJOL)

    Purpose: This paper presents a case study of an academic department's experience with evaluation. The purpose is to review the impact of student evaluation of teaching. The paper also introduces a new evaluation scoring method: the University of Zambia Staff Appraisal System (UNZASAS) method. Method: Anonymous ...

  1. Contribution of animal studies to evaluate the similarity of biosimilars to reference products.

    Science.gov (United States)

    van Meer, Peter J K; Ebbers, Hans C; Kooijman, Marlous; Gispen-de Wied, Christine C; Silva-Lima, Beatriz; Moors, Ellen H M; Schellekens, Huub

    2015-04-01

    The European Union (EU) was the first region to establish a regulatory framework for biosimilars, in which animal studies are required to confirm similarity to a reference product. However, animal studies described in European public assessment reports (EPARs) or marketing authorization applications (MAAs) did not identify clinically or toxicologically relevant differences despite differences in quality, suggesting that animal studies lack the sensitivity to confirm biosimilarity. Scientific advice provided learning opportunities to evolve existing guidance. Altogether, the data support a step-wise approach to develop biosimilars that focuses on quality and clinical efficacy of biosimilar. This approach might be more effective and does not necessarily require animal studies, which is also reflected in new EU draft guidance. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Bias During the Evaluation of Animal Studies?

    Directory of Open Access Journals (Sweden)

    Andrew Knight

    2012-02-01

    Full Text Available My recent book entitled The Costs and Benefits of Animal Experiments seeks to answer a key question within animal ethics, namely: is animal experimentation ethically justifiable? Or, more precisely, is it justifiable within the utilitarian cost:benefit framework that fundamentally underpins most regulations governing animal experimentation? To answer this question I reviewed more than 500 scientific publications describing animal studies, animal welfare impacts, and alternative research, toxicity testing and educational methodologies. To minimise bias I focused primarily on large-scale systematic reviews that had examined the human clinical and toxicological utility of animal studies. Despite this, Dr. Susanne Prankel recently reviewed my book in this journal, essentially accusing me of bias. However, she failed to provide any substantive evidence to refute my conclusions, let alone evidence of similar weight to that on which they are based. Those conclusions are, in fact, firmly based on utilitarian ethical reasoning, informed by scientific evidence of considerable strength, and I believe they are robust.

  3. Bias During the Evaluation of Animal Studies?

    Science.gov (United States)

    Knight, Andrew

    2012-01-01

    Simple Summary Animal experimentation evokes strong emotional responses in people on both sides of the debate surrounding its ethical status. However, the true level of its usefulness to society may only be discerned by careful examination of reliable scientific evidence. My recent book, The Costs and Benefits of Animal Experiments, reviewed more than 500 relevant scientific publications. Recently in this journal, however, a reviewer essentially accused me of bias. Yet the conclusions of my book are based on sound reasoning and strong evidence, and no critic has yet provided any substantive evidence to refute them. Abstract My recent book entitled The Costs and Benefits of Animal Experiments seeks to answer a key question within animal ethics, namely: is animal experimentation ethically justifiable? Or, more precisely, is it justifiable within the utilitarian cost:benefit framework that fundamentally underpins most regulations governing animal experimentation? To answer this question I reviewed more than 500 scientific publications describing animal studies, animal welfare impacts, and alternative research, toxicity testing and educational methodologies. To minimise bias I focused primarily on large-scale systematic reviews that had examined the human clinical and toxicological utility of animal studies. Despite this, Dr. Susanne Prankel recently reviewed my book in this journal, essentially accusing me of bias. However, she failed to provide any substantive evidence to refute my conclusions, let alone evidence of similar weight to that on which they are based. Those conclusions are, in fact, firmly based on utilitarian ethical reasoning, informed by scientific evidence of considerable strength, and I believe they are robust. PMID:26486779

  4. Children's Nomenclatural Adventurism and Medical Evaluation study.

    Science.gov (United States)

    Willis, Francis R; Adams, Stephen L; Doyle, Sarah; Everitt, Ian J; Lovegrove, Michael; Slee, Jennie; Sparrow, Annie; Willis, Judith

    2009-12-01

    The aim of this study was to determine whether there is an association between a child's first name and the likelihood of inpatient admission following presentation to a paediatric emergency department (ED). This was a retrospective review of electronic records held in the ED of an urban tertiary paediatric hospital. Data were obtained for all presentations up to the age of 16 years for a single month (n= 4260), each being allocated to 1 of the 10 predetermined first name categories. A statistically significant increased risk for hospital admission was found for the following first name categories: popular culture (relative risk (RR) = 1.91, P= 0.000, 95% confidence interval (CI) = 1.60-2.28), apparently unique (RR = 1.52, P= 0.000, 95% CI = 1.23-1.87), Old Testament (RR = 1.39, P= 0.001, 95% CI = 1.14-1.69) and surname as first name (RR = 1.36, P= 0.015, 95% CI = 1.07-1.72). Our data confirm the impression that children with certain categories of first names have an increased likelihood of admission to hospital after presenting to the ED. We speculate that our findings, which are in concordance with those from educational and psychological literature, may reflect socio-economic status and/or a 'self-fulfilling prophecy'. Further research may make it possible to assign names an RR rating (e.g. for hospital admission in the first 16 years of life), thus providing parents with another factor to consider when choosing names for their children. More studies are of course needed.

  5. Planck intermediate results. XXIX. All-sky dust modelling with Planck, IRAS, and WISE observations

    Science.gov (United States)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Alves, M. I. R.; Aniano, G.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Chamballu, A.; Chiang, H. C.; Christensen, P. R.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Couchot, F.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Draine, B. T.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Falgarone, E.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Ghosh, T.; Giard, M.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gregorio, A.; Gruppuso, A.; Guillet, V.; Hansen, F. K.; Hanson, D.; Harrison, D. L.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Holmes, W. A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Keihänen, E.; Keskitalo, R.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C. R.; Leonardi, R.; Levrier, F.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Natoli, P.; Nørgaard-Nielsen, H. U.; Novikov, D.; Novikov, I.; Oxborrow, C. A.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Pratt, G. W.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ristorcelli, I.; Rocha, G.; Roudier, G.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Santos, D.; Scott, D.; Spencer, L. D.; Stolyarov, V.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; Ysard, N.; Yvon, D.; Zacchei, A.; Zonca, A.

    2016-02-01

    We present all-sky modelling of the high resolution Planck, IRAS, and WISE infrared (IR) observations using the physical dust model presented by Draine & Li in 2007 (DL, ApJ, 657, 810). We study the performance and results of this model, and discuss implications for future dust modelling. The present work extends the DL dust modelling carried out on nearby galaxies using Herschel and Spitzer data to Galactic dust emission. We employ the DL dust model to generate maps of the dust mass surface density ΣMd, the dust optical extinction AV, and the starlight intensity heating the bulk of the dust, parametrized by Umin. The DL model reproduces the observed spectral energy distribution (SED) satisfactorily over most of the sky, with small deviations in the inner Galactic disk and in low ecliptic latitude areas, presumably due to zodiacal light contamination. In the Andromeda galaxy (M31), the present dust mass estimates agree remarkably well (within 10%) with DL estimates based on independent Spitzer and Herschel data. We compare the DL optical extinction AV for the diffuse interstellar medium (ISM) with optical estimates for approximately 2 × 105 quasi-stellar objects (QSOs) observed inthe Sloan Digital Sky Survey (SDSS). The DL AV estimates are larger than those determined towards QSOs by a factor of about 2, which depends on Umin. The DL fitting parameter Umin, effectively determined by the wavelength where the SED peaks, appears to trace variations in the far-IR opacity of the dust grains per unit AV, and not only in the starlight intensity. These results show that some of the physical assumptions of the DL model will need to be revised. To circumvent the model deficiency, we propose an empirical renormalization of the DL AV estimate, dependent of Umin, which compensates for the systematic differences found with QSO observations. This renormalization, made to match the AV estimates towards QSOs, also brings into agreement the DL AV estimates with those derived for

  6. ChIP-PIT: Enhancing the Analysis of ChIP-Seq Data Using Convex-Relaxed Pair-Wise Interaction Tensor Decomposition.

    Science.gov (United States)

    Zhu, Lin; Guo, Wei-Li; Deng, Su-Ping; Huang, De-Shuang

    2016-01-01

    In recent years, thanks to the efforts of individual scientists and research consortiums, a huge amount of chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experimental data have been accumulated. Instead of investigating them independently, several recent studies have convincingly demonstrated that a wealth of scientific insights can be gained by integrative analysis of these ChIP-seq data. However, when used for the purpose of integrative analysis, a serious drawback of current ChIP-seq technique is that it is still expensive and time-consuming to generate ChIP-seq datasets of high standard. Most researchers are therefore unable to obtain complete ChIP-seq data for several TFs in a wide variety of cell lines, which considerably limits the understanding of transcriptional regulation pattern. In this paper, we propose a novel method called ChIP-PIT to overcome the aforementioned limitation. In ChIP-PIT, ChIP-seq data corresponding to a diverse collection of cell types, TFs and genes are fused together using the three-mode pair-wise interaction tensor (PIT) model, and the prediction of unperformed ChIP-seq experimental results is formulated as a tensor completion problem. Computationally, we propose efficient first-order method based on extensions of coordinate descent method to learn the optimal solution of ChIP-PIT, which makes it particularly suitable for the analysis of massive scale ChIP-seq data. Experimental evaluation the ENCODE data illustrate the usefulness of the proposed model.

  7. A Case Study Showing Parameters Affecting the Quality of Education: Faculty Perspective

    Science.gov (United States)

    Kumari, Neeraj

    2014-01-01

    The study aims to examine the faculty members' perspective (age Wise, Gender Wise and Work Experience wise) of parameters affecting the quality of education in an affiliated Undergraduate Engineering Institution in Haryana. It is a descriptive type of research. The data has been collected with the help of 'Questionnaire Based Survey'. The sample…

  8. In vitro evaluation of the sealing ability of three newly developed root canal sealers: A bacterial microleakage study

    Science.gov (United States)

    Sobhani, Ehsan; Samadi-Kafil, Hossein; Pirzadeh, Ahmad; Jafari, Sanaz

    2016-01-01

    Background The purpose of this study was to compare the sealing ability of MTA Fillapex, Apatite Root Canal Sealer and AH26 sealers. Material and Methods The present in vitro study was carried out on 142 extracted single-rooted human mature teeth. The teeth were randomly divided into three experimental groups (n=44) and two control groups (n=5). Three root canal sealers were MTA Fillapex, Apatite Root Canal Sealer and AH26. The teeth in the control groups were either filled with no sealer or made completely impermeable. The root canals were prepared and obturated with gutta-percha and one of the sealers. The teeth were sterilized with ethylene oxide gas prior to the bacterial leakage assessment using Enterococcus faecalis. Leakage was evaluated every 24 hours for 90 days. Data were analyzed with descriptive statistical methods and chi-squared test. If the data were significant, a proper post hoc test was used. Statistical significance was set at P<0.05. Results The positive control specimens exhibited total bacterial penetration whilst the negative control specimens showed no evidence of bacterial penetration. At the end of the study, the analysis of microleakage with chi-squared test showed no significant differences between the experimental groups (P<0.05). The results of chi-squared test analyzing the pair-wise differences between the groups considering the numerical values for leakage day indicated the lowest leakage with AH26 and the highest with Apatite root sealer. Conclusions According to the results of the present study, sealing ability of AH26 was significantly higher than that of MTA Fillapex and Apatite Root Canal Sealer. Key words:Mineral Trioxide aggregate, root canal obturation, dental seal. PMID:27957271

  9. Evaluation of the Ramazzini Foundation Study of Methanol in Rats

    Science.gov (United States)

    Evaluation of the Ramazzini Foundation Study of Methanol in Rats: A Comparison of Diagnoses by the RF Study Pathologist and a Recent NTP Review Team, summarized by George Cruzan and submitted to the Methanol Institute

  10. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... of participants before using unfamiliar applications; consideration of time, effort and costs of conducting the simulation; technical maturity of the evaluated system; and allowing adequate preparation of simulation scenarios and simulation setting. Simulation studies are an interesting but time......-consuming approach, which can be used to evaluate newly developed health IT systems, particularly those systems that are not yet suffi ciently mature to undergo field evaluation studies....

  11. Simulation studies for the evaluation of health information technologies

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner; Binzer, Kristine

    2012-01-01

    It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...... of participants before using unfamiliar applications; consideration of time, effort and costs of conducting the simulation; technical maturity of the evaluated system; and allowing adequate preparation of simulation scenarios and simulation setting. Simulation studies are an interesting but time......-consuming approach, which can be used to evaluate newly developed health IT systems, particularly those systems that are not yet sufficiently mature to undergo field evaluation studies....

  12. Clinical Evaluation of Success of Primary Teeth Pulpotomy Using Mineral Trioxide Aggregate®, Laser and BiodentineTM- an In Vivo Study

    Science.gov (United States)

    Prasad, Madhu Ghanshyam; Vasa, Aron Arun Kumar; Divya, Gaddam; Thakur, Mukesh Singh; Saujanya, Kanithi

    2015-01-01

    Introduction Pulpotomy technique basically consists of removing the coronal pulp and fixing the radicular pulp with a medicament. It is the most widely accepted clinical procedure for treating primary teeth with coronal pulp inflammation caused by caries with no involvement of the radicular pulp. Aim To evaluate the success and efficacy of Mineral Trioxide Aggregate (MTA), Lasers and Biodentine as pulpotomy agents both clinically and radiographically. Materials and Methods In the present study, 60 primary molars in children whose pulpal status warranted pulpotomy were selected and randomly assigned into three groups that included MTA, Laser and Biodentine allocating 20 teeth to each group. The pulpotomy procedure was then performed on all selected teeth followed by restoration with stainless steel crowns. Later the patients were recalled for 3 months and 6 months for clinical and radiographic evaluation. Results Statistical analysis was done using Fisher exact test to determine pair wise comparison of three agents with respect to clinical and radiographic criteria. Kruskal-Wallis ANOVA, Mc Nemars test was applied to evaluate the efficacy of each agent between 3 months and 6 months. The results showed that maximum success rate was found in MTA group. However, the comparison between three groups was statistically not significant (pPulpotomies performed with either MTA, Laser or Biodentine are equally efficient with similar clinical/radiographic success and hence can be considered as alternatives to Formocresol. PMID:26023640

  13. Clinical Evaluation of Success of Primary Teeth Pulpotomy Using Mineral Trioxide Aggregate(®), Laser and Biodentine(TM)- an In Vivo Study.

    Science.gov (United States)

    Niranjani, Krothapalli; Prasad, Madhu Ghanshyam; Vasa, Aron Arun Kumar; Divya, Gaddam; Thakur, Mukesh Singh; Saujanya, Kanithi

    2015-04-01

    Pulpotomy technique basically consists of removing the coronal pulp and fixing the radicular pulp with a medicament. It is the most widely accepted clinical procedure for treating primary teeth with coronal pulp inflammation caused by caries with no involvement of the radicular pulp. To evaluate the success and efficacy of Mineral Trioxide Aggregate (MTA), Lasers and Biodentine as pulpotomy agents both clinically and radiographically. In the present study, 60 primary molars in children whose pulpal status warranted pulpotomy were selected and randomly assigned into three groups that included MTA, Laser and Biodentine allocating 20 teeth to each group. The pulpotomy procedure was then performed on all selected teeth followed by restoration with stainless steel crowns. Later the patients were recalled for 3 months and 6 months for clinical and radiographic evaluation. Statistical analysis was done using Fisher exact test to determine pair wise comparison of three agents with respect to clinical and radiographic criteria. Kruskal-Wallis ANOVA, Mc Nemars test was applied to evaluate the efficacy of each agent between 3 months and 6 months. The results showed that maximum success rate was found in MTA group. However, the comparison between three groups was statistically not significant (pPulpotomies performed with either MTA, Laser or Biodentine are equally efficient with similar clinical/radiographic success and hence can be considered as alternatives to Formocresol.

  14. WISE NMR characterization of nanoscale heterogeneity and mobility in supercontracted Nephila clavipes spider dragline silk.

    Science.gov (United States)

    Holland, Gregory P; Lewis, Randolph V; Yarger, Jeff L

    2004-05-12

    The addition of water to spider dragline silk results in fiber contraction to 50% its initial length and significant changes to the mechanical properties of the silk. This event has been termed supercontraction. A decrease in strength and increase in elasticity have been reported when the silk is in contact with water. Two-dimensional wide-line separation (WISE) nuclear magnetic resonance (NMR) is implemented to correlate (13)C chemical shifts with mobility by observing the corresponding (1)H line widths and line shapes in water-saturated spider dragline silk. The WISE NMR spectrum of the native silk exhibits (1)H line widths that are approximately 40 kHz for all carbon environments characteristic of a rigid organic system. In contrast, the water-saturated case displays a component of the (1)H line that is narrowed to approximately 5 kHz for the glycine C(alpha) and a newly resolved alanine helical environment while the alanine C(beta) corresponding to the beta-sheet conformation remains broad. These results indicate that water permeates the amorphous, glycine-rich matrix and not the crystalline, polyalanine beta-sheets. A delay time is added to the WISE NMR pulse sequence to monitor spin diffusion between the amorphous, mobile region and the crystalline domains. The time required for spin diffusion to reach spatial equilibrium is related to the length scale of the polyalanine crystallites. This technique is employed to measure crystalline domain sizes on the nanometer length scale in water-solvated spider dragline silk. These results provide further insight into the structure of spider silk and mechanism of supercontraction.

  15. VoxelStats: A MATLAB Package for Multi-Modal Voxel-Wise Brain Image Analysis.

    Science.gov (United States)

    Mathotaarachchi, Sulantha; Wang, Seqian; Shin, Monica; Pascoal, Tharick A; Benedet, Andrea L; Kang, Min Su; Beaudry, Thomas; Fonov, Vladimir S; Gauthier, Serge; Labbe, Aurélie; Rosa-Neto, Pedro

    2016-01-01

    In healthy individuals, behavioral outcomes are highly associated with the variability on brain regional structure or neurochemical phenotypes. Similarly, in the context of neurodegenerative conditions, neuroimaging reveals that cognitive decline is linked to the magnitude of atrophy, neurochemical declines, or concentrations of abnormal protein aggregates across brain regions. However, modeling the effects of multiple regional abnormalities as determinants of cognitive decline at the voxel level remains largely unexplored by multimodal imaging research, given the high computational cost of estimating regression models for every single voxel from various imaging modalities. VoxelStats is a voxel-wise computational framework to overcome these computational limitations and to perform statistical operations on multiple scalar variables and imaging modalities at the voxel level. VoxelStats package has been developed in Matlab(®) and supports imaging formats such as Nifti-1, ANALYZE, and MINC v2. Prebuilt functions in VoxelStats enable the user to perform voxel-wise general and generalized linear models and mixed effect models with multiple volumetric covariates. Importantly, VoxelStats can recognize scalar values or image volumes as response variables and can accommodate volumetric statistical covariates as well as their interaction effects with other variables. Furthermore, this package includes built-in functionality to perform voxel-wise receiver operating characteristic analysis and paired and unpaired group contrast analysis. Validation of VoxelStats was conducted by comparing the linear regression functionality with existing toolboxes such as glim_image and RMINC. The validation results were identical to existing methods and the additional functionality was demonstrated by generating feature case assessments (t-statistics, odds ratio, and true positive rate maps). In summary, VoxelStats expands the current methods for multimodal imaging analysis by allowing the

  16. Shape models of asteroids reconstructed from WISE data and sparse photometry

    Science.gov (United States)

    Durech, Josef; Hanus, Josef; Ali-Lagoa, Victor

    2017-10-01

    By combining sparse-in-time photometry from the Lowell Observatory photometry database with WISE observations, we reconstructed convex shape models for about 700 new asteroids and for other ~850 we derived 'partial' models with unconstrained ecliptic longitude of the spin axis direction. In our approach, the WISE data were treated as reflected light, which enabled us to directly join them with sparse photometry into one dataset that was processed by the lightcurve inversion method. This simplified treatment of thermal infrared data turned out to provide correct results, because in most cases the phase offset between optical and thermal lightcurves was small and the correct sidereal rotation period was determined. The spin and shape parameters derived from only optical data and from a combination of optical and WISE data were very similar. The new models together with those already available in the Database of Asteroid Models from Inversion Techniques (DAMIT) represent a sample of ~1650 asteroids. When including also partial models, the total sample is about 2500 asteroids, which significantly increases the number of models with respect to those that have been available so far. We will show the distribution of spin axes for different size groups and also for several collisional families. These observed distributions in general agree with theoretical expectations proving that smaller asteroids are more affected by YORP/Yarkovsky evolution. In asteroid families, we see a clear bimodal distribution of prograde/retrograde rotation that correlates with the position to the right/left from the center of the family measured by the semimajor axis.

  17. Fixed Pattern Noise pixel-wise linear correction for crime scene imaging CMOS sensor

    Science.gov (United States)

    Yang, Jie; Messinger, David W.; Dube, Roger R.; Ientilucci, Emmett J.

    2017-05-01

    Filtered multispectral imaging technique might be a potential method for crime scene documentation and evidence detection due to its abundant spectral information as well as non-contact and non-destructive nature. Low-cost and portable multispectral crime scene imaging device would be highly useful and efficient. The second generation crime scene imaging system uses CMOS imaging sensor to capture spatial scene and bandpass Interference Filters (IFs) to capture spectral information. Unfortunately CMOS sensors suffer from severe spatial non-uniformity compared to CCD sensors and the major cause is Fixed Pattern Noise (FPN). IFs suffer from "blue shift" effect and introduce spatial-spectral correlated errors. Therefore, Fixed Pattern Noise (FPN) correction is critical to enhance crime scene image quality and is also helpful for spatial-spectral noise de-correlation. In this paper, a pixel-wise linear radiance to Digital Count (DC) conversion model is constructed for crime scene imaging CMOS sensor. Pixel-wise conversion gain Gi,j and Dark Signal Non-Uniformity (DSNU) Zi,j are calculated. Also, conversion gain is divided into four components: FPN row component, FPN column component, defects component and effective photo response signal component. Conversion gain is then corrected to average FPN column and row components and defects component so that the sensor conversion gain is uniform. Based on corrected conversion gain and estimated image incident radiance from the reverse of pixel-wise linear radiance to DC model, corrected image spatial uniformity can be enhanced to 7 times as raw image, and the bigger the image DC value within its dynamic range, the better the enhancement.

  18. Quantification of pulmonary regurgitation in patients with repaired Tetralogy of Fallot by 2D phase-contrast MRI: Differences between the standard method of velocity averaging and a pixel-wise analysis.

    Science.gov (United States)

    Sotelo, Julio; Bächler, Pablo; Urbina, Jesús; Crelier, Gerard; Toro, Lida; Ferreiro, Myriam; Valverde, Israel; Andia, Marcelo; Tejos, Cristian; Irarrazaval, Pablo; Uribe, Sergio

    2017-01-01

    To compare the values of pulmonary regurgitation in patients with repaired Tetralogy of Fallot quantified from two-dimensional phase-contrast data, by using a new pixel-wise analysis and the standard velocity-averaging method. Quantitative in silico and in vivo analysis. Hospital Sótero del Río. The magnetic resonance images were acquired using a Philips Achieva 1.5T scanner. Twenty-five patients with repaired Tetralogy of Fallot who underwent cardiovascular magnetic resonance imaging requested by their referring physicians were included in this study. Using a computational fluid dynamics simulation, we validated our pixel-wise method, quantifying the error of our method in comparison with the standard method. The patients underwent a standard two-dimensional phase-contrast magnetic resonance imaging acquisition for quantifying pulmonary artery flow. Pulmonary regurgitation fraction was estimated by using our pixel-wise and the standard method. The two-dimensional flow profiles were inspected looking for simultaneous antegrade and retrograde flows in the same cardiac phase. Statistical analysis was performed with t-test for related samples, Bland-Altman plots, and Pearson correlation coefficient. Estimation of pulmonary regurgitation fraction using the pixel-wise analysis revealed higher values compared with the standard method (39 ± 16% vs. 30 ± 22%, p-value <0.01). Eight patients (32%) had a difference of more than 10% between methods. Analysis of two-dimensional flow profiles in these patients revealed simultaneous antegrade and retrograde flows through the pulmonary artery during systole-early diastole. Quantification of pulmonary regurgitation fraction in patients with repaired Tetralogy of Fallot through a pixel-wise analysis yields higher values of pulmonary regurgitation compared with the standard velocity-averaging method.

  19. Radio Santa Maria: a case study of participatory evaluation.

    Science.gov (United States)

    Mayo, J K; Green, C B; Vargas, M E

    1985-01-01

    Radio Santa Maria (RSM), established by the Catholic Church in the Dominican Republic in 1964, broadcasts programs leading to certificates at the primary and intermediate levels and stresses education as a tool to help individuals cope with their environment. This article describes the history of an evaluation of RSM based on the participation of RSM personnel. RSM staff carried out the field work, while members of the expatriate evaluation team helped to design the survey instruments, trained staff in evaluation techniques, and conducted the statistical analyses. A 1975 policy document served as the basis of the evaluation. An important advantage of the self-study approach was that the evaluation process itself resulted in program improvements during the study period. As active participants in the process, RSM staff developed important evaluation skills and a computerized information retrieval system was installed. A disadvantage of the participatory approach to program evaluation is the time required to build personnel relations and transfer technical skills. Compromises may be necessary that undermine professional standards and reduce data reliability. On the other hand, self-study can provide data of more depth than external evaluations. It can overcome the neglect of inputs and processes that characterizes traditional output-oriented evaluations. It is concluded that if the purpose of an evaluation is to improve an organization, it is useful to involve the entire organization in the process.

  20. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    management system did help to improve medication safety. This simulation study provided a good compromise between internal validity and external validity. However, several challenges need to be addressed when undertaking simulation evaluations including: preparation of adequate test cases; training......It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...

  1. VizieR Online Data Catalog: Distances to RRab stars from WISE and Gaia (Sesar+, 2017)

    Science.gov (United States)

    Sesar, B.; Fouesneau, M.; Price-Whelan, A. M.; Bailer-Jones, C. A. L.; Gould, A.; Rix, H.-W.

    2017-10-01

    To constrain the period-luminosity-metallicity (PLZ) relations for RR Lyrae stars in WISE W1 and W2 bands, we use TGAS trigonometric parallaxes (barω), spectroscopic metallicities ([Fe/H]; Fernley+ 1998, J/A+A/330/515), log-periods (logP, base 10), and apparent magnitudes (m; Klein+ 2014, J/MNRAS/440/L96) for 102 RRab stars within ~2.5kpc from the Sun. The E(B-V) reddening at a star's position is obtained from the Schlegel+ (1998ApJ...500..525S) dust map. (1 data file).

  2. TongueWise: Tongue-computer interface software for people with tetraplegia.

    Science.gov (United States)

    Caltenco, Hector A; Andreasen Struijk, Lotte N S; Breidegard, Bjorn

    2010-01-01

    Many computer interfaces and assistive devices for people with motor disabilities limit the input dimensionality from user to system, in many cases leading to single switch interfaces where the user can only press one button. This can, either limit the level of direct access to the functionalities of the operating system, or slow down speed of interaction. In this paper we present TongueWise: a software developed for a tongue computer interface that can be activated with the tip of the tongue and that provides direct input that covers most of the standard keyboard and mouse commands.

  3. Pixel-wise decay parameter adaption for nonlocal means image denoising

    Science.gov (United States)

    Zhan, Yi; Ding, Mingyue; Zhang, Xuming

    2013-10-01

    The globally fixed decay parameter is generally adopted in the traditional nonlocal means method for similarity computation, which has a negative influence on its restoration performance. To address this problem, we propose to adaptively tune the decay parameter for each image pixel using the golden section search method based on the pixel-wise minimum mean square error, which can be estimated using the prefiltered result and the estimated noise component. The quantitative and subjective comparisons of restoration performance among the proposed method and several state-of-the-art methods indicate that it can achieve a better performance in noise reduction, artifact avoidance, and detail preservation.

  4. How prevalent and costly are Choosing Wisely low-value services? Evidence from Medicare beneficiaries.

    Science.gov (United States)

    Collado, Megan

    2014-10-01

    (1) Through the Choosing Wisely initiative, medical specialty societies identified non-indicated cardiac testing in low-risk patients and short-interval dual-energy X-ray absorptiometry (DXA) or bone density testing as low-value care. (2) Nationally, 13 percent of low-risk Medicare beneficiaries received non-indicated cardiac tests, and 10 percent of DXAs reimbursed by Medicare were administered at inappropriately short intervals. There is significant geographic variation in the provision of these services. (2) Carefully designed policy and payment changes will likely prove most effective in reducing low-value care.

  5. OtherWise The Wisdom You Need to Succeed in a Diverse and Divisive World

    CERN Document Server

    Martin, Dick

    2012-01-01

    Everyone puts multiethnic faces in marketing materials, but itÆs mostly a token gesture. Because even as the U.S. grows increasingly diverse, most professionals have little real knowledge of those different from themselves. OtherWise is a deep and engaging exploration of diversity in America and how we can bridge differencesùacross race, ethnicity, culture, sexual orientation, faith, and even politics. It goes far beyond census data into the realm of cognitive and social science, helping readers break through stereotypes and fears to a profound understanding of people unlike themselves. This i

  6. Learning Piece-wise Linear Models from Large Scale Data for Ad Click Prediction

    OpenAIRE

    Gai, Kun; Zhu, Xiaoqiang; Li, Han; Liu, Kai; Wang, Zhe

    2017-01-01

    CTR prediction in real-world business is a difficult machine learning problem with large scale nonlinear sparse data. In this paper, we introduce an industrial strength solution with model named Large Scale Piece-wise Linear Model (LS-PLM). We formulate the learning problem with $L_1$ and $L_{2,1}$ regularizers, leading to a non-convex and non-smooth optimization problem. Then, we propose a novel algorithm to solve it efficiently, based on directional derivatives and quasi-Newton method. In a...

  7. On the Exact BER of Bit-Wise Demodulators for One-Dimensional Constellations

    OpenAIRE

    Ivanov, Mikhail; Brannstrom, Fredrik; Alvarado, Alex; Agrell, Erik

    2013-01-01

    The optimal bit-wise demodulator for M-ary pulse amplitude modulation (PAM) over the additive white Gaussian noise channel is analyzed in terms of uncoded bit-error rate (BER). New closed-form BER expressions for 4-PAM with any labeling are developed. Moreover, closed-form BER expressions for 11 out of 23 possible bit patterns for 8-PAM are presented, which enable us to obtain the BER for 8-PAM with some of the most popular labelings, including the binary reflected Gray code and the natural b...

  8. Automated novelty detection in the WISE survey with one-class support vector machines

    Science.gov (United States)

    Solarz, A.; Bilicki, M.; Gromadzki, M.; Pollo, A.; Durkalec, A.; Wypych, M.

    2017-10-01

    Wide-angle photometric surveys of previously uncharted sky areas or wavelength regimes will always bring in unexpected sources - novelties or even anomalies - whose existence and properties cannot be easily predicted from earlier observations. Such objects can be efficiently located with novelty detection algorithms. Here we present an application of such a method, called one-class support vector machines (OCSVM), to search for anomalous patterns among sources preselected from the mid-infrared AllWISE catalogue covering the whole sky. To create a model of expected data we train the algorithm on a set of objects with spectroscopic identifications from the SDSS DR13 database, present also in AllWISE. The OCSVM method detects as anomalous those sources whose patterns - WISE photometric measurements in this case - are inconsistent with the model. Among the detected anomalies we find artefacts, such as objects with spurious photometry due to blending, but more importantly also real sources of genuine astrophysical interest. Among the latter, OCSVM has identified a sample of heavily reddened AGN/quasar candidates distributed uniformly over the sky and in a large part absent from other WISE-based AGN catalogues. It also allowed us to find a specific group of sources of mixed types, mostly stars and compact galaxies. By combining the semi-supervised OCSVM algorithm with standard classification methods it will be possible to improve the latter by accounting for sources which are not present in the training sample, but are otherwise well-represented in the target set. Anomaly detection adds flexibility to automated source separation procedures and helps verify the reliability and representativeness of the training samples. It should be thus considered as an essential step in supervised classification schemes to ensure completeness and purity of produced catalogues. The catalogues of outlier data are only available at the CDS via anonymous ftp to http

  9. Development of Fuzzy Multi Criteria Decision by Generalized Trapezoidal Pair-Wise Comparison Matrices

    Directory of Open Access Journals (Sweden)

    Rahim Saneifard

    2013-02-01

    Full Text Available One problem is that managers and experts to decide how to choose the best option among several options according to the decision criteria.In this paper we propose a new Analytic hierarchy process is a decision support tool which can be used to solve complex decision problems and also a new multi criteria decision making involves a series of techniques that allows a range of criteria related a topic in a pair-wise comparison matrices are rating and weighting, then ranked. In this paper a special SW Microsoft Excel add-in named VISIO and MATLB were use.

  10. Quicksort, largest bucket, and min-wise hashing with limited independence

    DEFF Research Database (Denmark)

    Knudsen, Mathias Bæk Tejs; Stöckel, Morten

    2015-01-01

    to be k-independent if every variable is uniform and every size k subset is independent. In this paper we consider three classic algorithms under limited independence. Besides the theoretical interest in removing the unrealistic assumption of full independence, the work is motivated by lower independence...... being more practical. We provide new bounds for randomized quicksort, min-wise hashing and largest bucket size under limited independence. Our results can be summarized as follows. Randomized Quicksort. When pivot elements are computed using a 5-independent hash function, Karloff and Raghavan, J.ACM’93...

  11. Linear-Time Non-Malleable Codes in the Bit-Wise Independent Tampering Model

    DEFF Research Database (Denmark)

    Cramer, Ronald; Damgård, Ivan Bjerre; Döttling, Nico

    Non-malleable codes were introduced by Dziembowski et al. (ICS 2010) as coding schemes that protect a message against tampering attacks. Roughly speaking, a code is non-malleable if decoding an adversarially tampered encoding of a message m produces the original message m or a value m' (eventuall...... non-malleable codes of Agrawal et al. (TCC 2015) and of Cher- aghchi and Guruswami (TCC 2014) and improves the previous result in the bit-wise tampering model: it builds the first non-malleable codes with linear-time complexity and optimal-rate (i.e. rate 1 - o(1))....

  12. Step-wise and punctuated genome evolution drive phenotype changes of tumor cells.

    Science.gov (United States)

    Stepanenko, Aleksei; Andreieva, Svitlana; Korets, Kateryna; Mykytenko, Dmytro; Huleyuk, Nataliya; Vassetzky, Yegor; Kavsan, Vadym

    2015-01-01

    The pattern of genome evolution can be divided into two phases: the step-wise continuous phase (step-wise clonal evolution, stable dominant clonal chromosome aberrations (CCAs), and low frequency of non-CCAs, NCCAs) and punctuated phase (marked by elevated NCCAs and transitional CCAs). Depending on the phase, system stresses (the diverse CIN promoting factors) may lead to the very different phenotype responses. To address the contribution of chromosome instability (CIN) to phenotype changes of tumor cells, we characterized CCAs/NCCAs of HeLa and HEK293 cells, and their derivatives after genotoxic stresses (a stable plasmid transfection, ectopic expression of cancer-associated CHI3L1 gene or treatment with temozolomide) by conventional cytogenetics, copy number alterations (CNAs) by array comparative genome hybridization, and phenotype changes by cell viability and soft agar assays. Transfection of either the empty vector pcDNA3.1 or pcDNA3.1_CHI3L1 into 293 cells initiated the punctuated genome changes. In contrast, HeLa_CHI3L1 cells demonstrated the step-wise genome changes. Increased CIN correlated with lower viability of 293_pcDNA3.1 cells but higher colony formation efficiency (CFE). Artificial CHI3L1 production in 293_CHI3L1 cells increased viability and further contributed to CFE. The opposite growth characteristics of 293_CHI3L1 and HeLa_CHI3L1 cells were revealed. The effect and function of a (trans)gene can be opposite and versatile in cells with different genetic network, which is defined by genome context. Temozolomide treatment of 293_pcDNA3.1 cells intensified the stochastic punctuated genome changes and CNAs, and significantly reduced viability and CFE. In contrast, temozolomide treatment of HeLa_CHI3L1 cells promoted the step-wise genome changes, CNAs, and increased viability and CFE, which did not correlate with the ectopic CHI3L1 production. Thus, consistent coevolution of karyotypes and phenotypes was observed. CIN as a driving force of genome

  13. Domain Decomposition Strategy for Pin-wise Full-Core Monte Carlo Depletion Calculation with the Reactor Monte Carlo Code

    Directory of Open Access Journals (Sweden)

    Jingang Liang

    2016-06-01

    Full Text Available Because of prohibitive data storage requirements in large-scale simulations, the memory problem is an obstacle for Monte Carlo (MC codes in accomplishing pin-wise three-dimensional (3D full-core calculations, particularly for whole-core depletion analyses. Various kinds of data are evaluated and quantificational total memory requirements are analyzed based on the Reactor Monte Carlo (RMC code, showing that tally data, material data, and isotope densities in depletion are three major parts of memory storage. The domain decomposition method is investigated as a means of saving memory, by dividing spatial geometry into domains that are simulated separately by parallel processors. For the validity of particle tracking during transport simulations, particles need to be communicated between domains. In consideration of efficiency, an asynchronous particle communication algorithm is designed and implemented. Furthermore, we couple the domain decomposition method with MC burnup process, under a strategy of utilizing consistent domain partition in both transport and depletion modules. A numerical test of 3D full-core burnup calculations is carried out, indicating that the RMC code, with the domain decomposition method, is capable of pin-wise full-core burnup calculations with millions of depletion regions.

  14. The MIXR sample: AGN activity versus star formation across the cross-correlation of WISE, 3XMM, and FIRST/NVSS

    Science.gov (United States)

    Mingo, B.; Watson, M. G.; Rosen, S. R.; Hardcastle, M. J.; Ruiz, A.; Blain, A.; Carrera, F. J.; Mateos, S.; Pineau, F.-X.; Stewart, G. C.

    2016-11-01

    We cross-correlate the largest available mid-infrared (Wide-field Infrared Survey Explorer - WISE), X-ray (3XMM) and radio (Faint Images of the Radio Sky at Twenty centimetres+NRAO VLA Sky Survey) catalogues to define the MIXR sample of AGN and star-forming galaxies. We pre-classify the sources based on their positions on the WISE colour/colour plot, showing that the MIXR triple selection is extremely effective to diagnose the star formation and AGN activity of individual populations, even on a flux/magnitude basis, extending the diagnostics to objects with luminosities and redshifts from SDSS DR12. We recover the radio/mid-IR star formation correlation with great accuracy, and use it to classify our sources, based on their activity, as radio-loud and radio-quiet active galactic nuclei (AGN), low excitation radio galaxies/low ionization nuclear emission line regions, and non-AGN galaxies. These diagnostics can prove extremely useful for large AGN and galaxy samples, and help develop ways to efficiently triage sources when data from the next generation of instruments becomes available. We study bias in detail, and show that while the widely used WISE colour selections for AGN are very successful at cleanly selecting samples of luminous AGN, they miss or misclassify a substantial fraction of AGN at lower luminosities and/or higher redshifts. MIXR also allows us to test the relation between radiative and kinetic (jet) power in radio-loud AGN, for which a tight correlation is expected due to a mutual dependence on accretion. Our results highlight that long-term AGN variability, jet regulation, and other factors affecting the Q/Lbol relation, are introducing a vast amount of scatter in this relation, with dramatic potential consequences on our current understanding of AGN feedback and its effect on star formation.

  15. A Study on Developing Evaluation Criteria for Electronic Resources in Evaluation Indicators of Libraries

    Science.gov (United States)

    Noh, Younghee

    2010-01-01

    This study aimed to improve the current state of electronic resource evaluation in libraries. While the use of Web DB, e-book, e-journal, and other e-resources such as CD-ROM, DVD, and micro materials is increasing in libraries, their use is not comprehensively factored into the general evaluation of libraries and may diminish the reliability of…

  16. Integrative Evaluation: An Emerging Role for Classroom Studies of CAL.

    Science.gov (United States)

    Draper, Stephen W.; And Others

    1996-01-01

    Reviews evaluations of CAL (computer-assisted learning) in use at the University of Glasgow (Scotland). Topics include methods used; prior knowledge; learning motivation; attitude measures; confidence logs; knowledge quizzes; study habits; Hawthorne effects; formative, summative, illuminative, and integrative evaluation; quality assurance…

  17. An evaluation study of the sputum smear concentration technique for ...

    African Journals Online (AJOL)

    This study was carried out at the Yaoundé University Teaching Hospital and is aimed at evaluating the sputum smear concentration technique in the laboratory diagnosis of pulmonary TB. Sputum samples were collected in screw-cap tight containers and evaluated by both the direct and concentrated methods. Microscopy of ...

  18. A modified GFP facilitates counting membrane protein subunits by step-wise photobleaching in Arabidopsis.

    Science.gov (United States)

    Song, Kai; Xue, Yiqun; Wang, Xiaohua; Wan, Yinglang; Deng, Xin; Lin, Jinxing

    2017-06-01

    Membrane proteins exert functions by forming oligomers or molecular complexes. Currently, step-wise photobleaching has been applied to count the fluorescently labelled subunits in plant cells, for which an accurate and reliable control is required to distinguish individual subunits and define the basal fluorescence. However, the common procedure using immobilized GFP molecules is obviously not applicable for analysis in living plant cells. Using the spatial intensity distribution analysis (SpIDA), we found that the A206K mutation reduced the dimerization of GFP molecules. Further ectopic expression of Myristoyl-GFPA206K driven by the endogenous AtCLC2 promoter allowed imaging of individual molecules at a low expression level. As a result, the percentage of dimers in the transgenic pCLC2::Myristoyl-mGFPA206K line was significantly reduced in comparison to that of the pCLC2::Myristoyl-GFP line, confirming its application in defining the basal fluorescence intensity of GFP. Taken together, our results demonstrated that pCLC2::Myristoyl-mGFPA206K can be used as a standard control for monomer GFP, facilitating the analysis of the step-wise photobleaching of membrane proteins in Arabidopsis thaliana. Copyright © 2017 Elsevier GmbH. All rights reserved.

  19. GPS on Every Roof, GPS Sensor Network for Post-Seismic Building-Wise Damage Identification

    Directory of Open Access Journals (Sweden)

    Kenji Oguni

    2013-12-01

    Full Text Available Development of wireless sensor network equipped with GPS for post-seismic building-wise damage identification is presented in this paper. This system is called GPS on Every Roof. Sensor node equipped with GPS antenna and receiver is installed on the top of the roof of each and every building. The position of this sensor node is measured before and after earthquake. The final goal of this system is to i identify the displacement of the roof of each house and ii collect the information of displacement of the roof of the houses through wireless communication. Superposing this information on GIS, building-wise damage distribution due to earthquake can be obtained. The system overview, hardware and some of the key components of the system such as on-board GPS relative positioning algorithm to achieve the accuracy in the order of several centimeters are described in detail. Also, the results from a field experiment using a wireless sensor network with 39 sensor nodes are presented.

  20. Evidence-based guidelines for wise use of electronic games by children.

    Science.gov (United States)

    Straker, Leon; Abbott, Rebecca; Collins, Rachel; Campbell, Amity

    2014-01-01

    Electronic games (e-games) are widely used by children, often for substantial durations, yet to date there are no evidence-based guidelines regarding their use. The aim of this paper is to present guidelines for the wise use of e-games by children based on a narrative review of the research. This paper proposes a model of factors that influence child-e-games interaction. It summarises the evidence on positive and negative effects of use of e-games on physical activity and sedentary behaviour, cardio-metabolic health, musculoskeletal health, motor coordination, vision, cognitive development and psychosocial health. Available guidelines and the role of guidelines are discussed. Finally, this information is compiled into a clear set of evidence-based guidelines, about wise use of e-games by children, targeting children, parents, professionals and the e-game industry. These guidelines provide an accessible synthesis of available knowledge and pragmatic guidelines based on e-game specific evidence and related research.

  1. Information Fields Navigation with Piece-Wise Polynomial Approximation for High-Performance OFDM in WSNs

    Directory of Open Access Journals (Sweden)

    Wei Wei

    2013-01-01

    Full Text Available Since Wireless sensor networks (WSNs are dramatically being arranged in mission-critical applications,it changes into necessary that we consider application requirements in Internet of Things. We try to use WSNs to assist information query and navigation within a practical parking spaces environment. Integrated with high-performance OFDM by piece-wise polynomial approximation, we present a new method that is based on a diffusion equation and a position equation to accomplish the navigation process conveniently and efficiently. From the point of view of theoretical analysis, our jobs hold the lower constraint condition and several inappropriate navigation can be amended. Information diffusion and potential field are introduced to reach the goal of accurate navigation and gradient descent method is applied in the algorithm. Formula derivations and simulations manifest that the method facilitates the solution of typical sensor network configuration information navigation. Concurrently, we also treat channel estimation and ICI mitigation for very high mobility OFDM systems, and the communication is between a BS and mobile target at a terrible scenario. The scheme proposed here combines the piece-wise polynomial expansion to approximate timevariations of multipath channels. Two near symbols are applied to estimate the first-and second-order parameters. So as to improve the estimation accuracy and mitigate the ICI caused by pilot-aided estimation, the multipath channel parameters were reestimated in timedomain employing the decided OFDM symbol. Simulation results show that this method would improve system performance in a complex environment.

  2. Anima/Animus and Wise Old Man in Six Characters in Search of an Author

    Directory of Open Access Journals (Sweden)

    Ali Jamalinesari

    2015-06-01

    Full Text Available The word ‘archetype’ is derived from the Greek words arche meaning ‘first’ and type meaning ‘imprint’ or ‘pattern’. Actually, the archetypes are like deposits of experiences that have been frequently repeated in the history of human beings. They are present in all humans from birth. They can be represented in dreams, fantasies, or as a story, as a pattern or image such as mandala, or as an archetypal or mythical character. Jung believes that the archetypes are not memories of past experiences but are forms without content that represent a certain kind of perception and action. They offer a kind of preparation to produce similar mythical ideas again and again.  Jung discovers that, since we have different cultures with different people, we have different kinds of archetypes – some known, many others yet to be discovered. In this regards, in the followings the archetypes Anima/Animus and Wise Old Man are discussed in Six Characters in Search of an Author to show how the question of reality, illusion and the oxymoron illusive reality as a major theme haunts Pirandello`s play. Keywords: Jung, Anima, Animus, Wise Old Man, Pirandello

  3. Path-Wise Test Data Generation Based on Heuristic Look-Ahead Methods

    Directory of Open Access Journals (Sweden)

    Ying Xing

    2014-01-01

    Full Text Available Path-wise test data generation is generally considered an important problem in the automation of software testing. In essence, it is a constraint optimization problem, which is often solved by search methods such as backtracking algorithms. In this paper, the backtracking algorithm branch and bound and state space search in artificial intelligence are introduced to tackle the problem of path-wise test data generation. The former is utilized to explore the space of potential solutions and the latter is adopted to construct the search tree dynamically. Heuristics are employed in the look-ahead stage of the search. Dynamic variable ordering is presented with a heuristic rule to break ties, values of a variable are determined by the monotonicity analysis on branching conditions, and maintaining path consistency is achieved through analysis on the result of interval arithmetic. An optimization method is also proposed to reduce the search space. The results of empirical experiments show that the search is conducted in a basically backtrack-free manner, which ensures both test data generation with promising performance and its excellence over some currently existing static and dynamic methods in terms of coverage. The results also demonstrate that the proposed method is applicable in engineering.

  4. VizieR Online Data Catalog: WISE W1/W2 Tully-Fisher relation calibrator data (Neill+, 2014)

    Science.gov (United States)

    Neill, J. D.; Seibert, M.; Tully, R. B.; Courtois, H.; Sorce, J. G.; Jarrett, T. H.; Scowcroft, V.; Masci, F. J.

    2017-04-01

    We have instigated a separate project to provide high-quality surface photometry of all WISE galaxies larger than 0.8' on the sky. The WISE Nearby Galaxy Atlas (WNGA; M. Seibert et al., in preparation) will provide photometry that is quality controlled for over 20000 galaxies. This photometry, optimized for extended sources, significantly reduces the resulting scatter in the Tully-Fisher relation (here after TFR) calibration and thus improves the resulting distances. Having an accurate calibration of the TFR for these two WISE passbands will allow the use of this large sample to explore the structure and dynamics of local galaxy bulk flows. With the current tally, there are 310 cluster calibrators with WISE W1 and W2 photometry, compared with 213 available to Sorce et al. (2013, J/ApJ/765/94) for the Spitzer calibration, and 291 of the 310 WISE calibrators have I-band photometry, compared with the 267 available to Tully & Courtois (2012ApJ...749...78T) for the previous I-band calibration. (1 data file).

  5. Sub-stellar objects with habitable-zone temperatures: A new search for Y dwarfs in WISE

    Directory of Open Access Journals (Sweden)

    Day-Jones Avril

    2013-04-01

    Full Text Available A method is defined for using the maximum sensitivity of WISE to find late T and Y dwarfs. This requires a WISE detection only in the W2-band and uses the statistical properties of the WISE multi-frame measurements and profile fit photometry to reject contamination resulting from non-point-like objects, variables and moving sources. To trace our desired parameter space we use a control sample of isolated non-moving non-variable point sources from the SDSS, and identify a sample of 158 WISE W2-only candidates down to a signal-to-noise limit of 8. For signal-to-noise ranges >10 and 8-10 respectively, ∼45% and ∼90% of our sample fall outside the criteria published by the WISE team (Kirkpatrick et al. 2012, due mainly to the type of constraints placed on the number of individual W2 detections. We present some early follow-up of our sample and identify two new very late objects with high proper motion (∼1.3 and ∼1.8 arcsec yr−1. Based on colour, brightness and proper motion, these object are either ∼T9 dwarfs with thick-disk/halo kinematics, or Y dwarfs with more disk-like kinematics. Reduced proper motion diagrams are also presented which suggest that late T and Y dwarfs may have a much higher thick-disk/halo population fraction than earlier objects.

  6. NuSTAR Observations of WISE J1036+0449, A Galaxy at zeta approx 1 Obscured by Hot Dust

    Science.gov (United States)

    Ricci, C.; Assef, R. J.; Stern, Daniel K.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A.W.; Zhang, William W.; hide

    2017-01-01

    Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer's all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z > 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z approx. 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (L(sub BOL) approx. = 8 x 10(exp 46) erg/s). We find evidence of a broadened component in Mg II, which would imply a black hole mass of M(BH) approx. = 2 x 10(exp 8) Stellar Mass and an Eddington ratio of lambda(sub Edd) approx. = 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of N(sub H) approx. = (2-15) x 10(exp 23)/sq cm. The source has an intrinsic 2-10 keV luminosity of approx. 6 x 10(exp 44) erg/s, a value significantly lower than that expected from the mid-infrared X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z < or approx. 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.

  7. NuSTAR Observations of WISE J1036+0449, A Galaxy at Z Approx. 1 Obscured by Hot Dust

    Science.gov (United States)

    Ricci, C.; Assef, R. J.; Stern, D.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A. W.; Boggs, S.; hide

    2017-01-01

    Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer's all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z > 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z approx. 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (L(BOL) approx. = 8 x 10(exp 46) erg/s). We find evidence of a broadened component in Mg II, which would imply a black hole mass of M(BH) approx. = 2 x 10(exp 8) Stellar Mass and an Eddington ratio of lambda(Edd) approx. = 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of N(H) approx. = (2-15) x 10(exp 23)/sq cm. The source has an intrinsic 2-10 keV luminosity of approx. 6 x 10(exp 44) erg/s, a value significantly lower than that expected from the mid-infrared X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z < or approx. 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.

  8. NuSTAR Observations of WISE J1036+0449, a Galaxy at z~1 Obscured by Hot Dust

    Science.gov (United States)

    Ricci, C.; Assef, R. J.; Stern, D.; Nikutta, R.; Alexander, D. M.; Asmus, D.; Ballantyne, D. R.; Bauer, F. E.; Blain, A. W.; Boggs, S.; Boorman, P. G.; Brandt, W. N.; Brightman, M.; Chang, C. S.; Chen, C.-T. J.; Christensen, F. E.; Comastri, A.; Craig, W. W.; Díaz-Santos, T.; Eisenhardt, P. R.; Farrah, D.; Gandhi, P.; Hailey, C. J.; Harrison, F. A.; Jun, H. D.; Koss, M. J.; LaMassa, S.; Lansbury, G. B.; Markwardt, C. B.; Stalevski, M.; Stanley, F.; Treister, E.; Tsai, C.-W.; Walton, D. J.; Wu, J. W.; Zappacosta, L.; Zhang, W. W.

    2017-01-01

    Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer’s all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z> 1.5, due in part to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z˜ 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 ({L}{Bol}≃ 8× {10}46 {erg} {{{s}}}-1). We find evidence of a broadened component in Mg II, which would imply a black hole mass of {M}{BH}≃ 2× {10}8 {M}⊙ and an Eddington ratio of {λ }{Edd}≃ 2.7. WISE J1036+0449 is the first hot DOG detected by the Nuclear Spectroscopic Telescope Array, and observations show that the source is heavily obscured, with a column density of {N}{{H}}≃ (2{--}15)× {10}23 {{cm}}-2. The source has an intrinsic 2-10 keV luminosity of ˜ 6× {10}44 {erg} {{{s}}}-1, a value significantly lower than that expected from the mid-infrared/X-ray correlation. We also find that other hot DOGs observed by X-ray facilities show a similar deficiency of X-ray flux. We discuss the origin of the X-ray weakness and the absorption properties of hot DOGs. Hot DOGs at z≲ 1 could be excellent laboratories to probe the characteristics of the accretion flow and of the X-ray emitting plasma at extreme values of the Eddington ratio.

  9. Chronic toxicological evaluation and reversibility studies of Moringa ...

    African Journals Online (AJOL)

    Chronic toxicological evaluation and reversibility studies of Moringa oleifera ethanolic seed extract in Wistar rats. ... of the animals were sacrificed and blood samples collected for determination of biochemical and haematological parameters; antioxidants and malondialdehyde (MDA); sperm count, motility and morphology.

  10. Guidance for Identifying, Selecting and Evaluating Open Literature Studies

    Science.gov (United States)

    This guidance for Office of Pesticide Program staff will assist in their evaluation of open literature studies of pesticides. It also describes how we identify, select, and ensure that data we use in risk assessments is of sufficient scientific quality.

  11. Overview of the Building Assessment Survey and Evaluation Study

    Science.gov (United States)

    The Building Assessment Survey and Evaluation (BASE) study was conducted over a five-year period from 1994-1998, to characterize determinants of indoor air quality (IAQ) and occupant perceptions in representative public and commercial office buildings.

  12. Synthesis, biological evaluation and molecular docking studies of ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 128; Issue 6. Synthesis, biological evaluation and molecular docking studies of some novel cyclopropane carbohydrazide derivatives as potential anticancer agents. PONNAPALLI VEERABHADRA SWAMY PULLAIAH CHINA KAMBHAMPATI KOTHAPALLI BONNOTH ...

  13. Cliffs' GRE StudyWare Package: A Critical Evaluation.

    Science.gov (United States)

    Brooke, Stephanie L.

    1995-01-01

    Provides evaluation of Cliffs' GRE StudyWare package (Bobrow, 1992). Discusses the educational implications of using Cliffs' approach, in addition to focusing on software considerations. Makes recommendations concerning Cliffs' method for Graduate Record Examination (GRE) preparation. (Author/LKS)

  14. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    system on the appropriateness of prescriptions and drugrelated activities, including laboratory test ordering or medication changes. This article presents the results of a controlled simulation study with 50 simulation runs, including ten doctors and fi ve simulation patients, and discusses experiences......It is essential for new health information technologies (IT) to undergo rigorous evaluations to ensure they are effective and safe for use in real-world situations. However, evaluation of new health IT is challenging, as field studies are often not feasible when the technology being evaluated...

  15. Evaluation systems for clinical governance development: a comparative study.

    Science.gov (United States)

    Hooshmand, Elaheh; Tourani, Sogand; Ravaghi, Hamid; Ebrahimipour, Hossein

    2014-01-01

    Lack of scientific and confirmed researches and expert knowledge about evaluation systems for clinical governance development in Iran have made studies on different evaluation systems for clinical governance development a necessity. These studies must provide applied strategies to design criteria of implementing clinical governance for hospital's accreditation. This is a descriptive and comparative study on development of clinical governance models all over the world. Data have been gathered by reviewing related articles. Models have been studied in comprehensive review method. The evaluated models of clinical governance development were Australian, NHS, SPOCK and OPTIGOV. The final aspects extracted from these models were Responsiveness, Policies and Strategies, Organizational Structure, Allocating Resources, Education and Occupational Development, Performance Evaluation, External Evaluation, Patient Oriented Approach, Risk Management, Personnel's Participation, Information Technology, Human Resources, Research and Development, Evidence Based Medicine, Clinical Audit, Health Technology Assessment and Quality. These results are applicable for completing the present criteria which evaluating clinical governance application and provide practical framework to evaluate country's hospital on the basis of clinical governance elements.

  16. Evaluation systems for clinical governance development: a comparative study.

    Directory of Open Access Journals (Sweden)

    Elaheh Hooshmand

    2014-08-01

    Full Text Available Lack of scientific and confirmed researches and expert knowledge about evaluation systems for clinical governance development in Iran have made studies on different evaluation systems for clinical governance development a necessity. These studies must provide applied strategies to design criteria of implementing clinical governance for hospital's accreditation. This is a descriptive and comparative study on development of clinical governance models all over the world. Data have been gathered by reviewing related articles. Models have been studied in comprehensive review method. The evaluated models of clinical governance development were Australian, NHS, SPOCK and OPTIGOV. The final aspects extracted from these models were Responsiveness, Policies and Strategies, Organizational Structure, Allocating Resources, Education and Occupational Development, Performance Evaluation, External Evaluation, Patient Oriented Approach, Risk Management, Personnel's Participation, Information Technology, Human Resources, Research and Development, Evidence Based Medicine, Clinical Audit, Health Technology Assessment and Quality. These results are applicable for completing the present criteria which evaluating clinical governance application and provide practical framework to evaluate country's hospital on the basis of clinical governance elements.

  17. Stage-Wise Identification and Analysis of miRNA from Root-Knot Nematode Meloidogyne incognita.

    Science.gov (United States)

    Subramanian, Parthiban; Choi, In-Chan; Mani, Vimalraj; Park, Junhyung; Subramaniyam, Sathiyamoorthy; Choi, Kang-Hyun; Sim, Joon-Soo; Lee, Chang-Muk; Koo, Ja Choon; Hahn, Bum-Soo

    2016-10-21

    In this study, we investigated global changes in miRNAs of Meloidogyne incognita throughout its life cycle. Small RNA sequencing resulted in approximately 62, 38, 38, 35, and 39 Mb reads in the egg, J2, J3, J4, and female stages, respectively. Overall, we identified 2724 known and 383 novel miRNAs (read count > 10) from all stages, of which 169 known and 13 novel miRNA were common to all the five stages. Among the stage-specific miRNAs, miR-286 was highly expressed in eggs, miR-2401 in J2, miR-8 and miR-187 in J3, miR-6736 in J4, and miR-17 in the female stages. These miRNAs are reported to be involved in embryo and neural development, muscular function, and control of apoptosis. Cluster analysis indicated the presence of 91 miRNA clusters, of which 36 clusters were novel and identified in this study. Comparison of miRNA families with other nematodes showed 17 families to be commonly absent in animal parasitic nematodes and M. incognita. Validation of 43 predicted common and stage-specific miRNA by quantitative PCR (qPCR) indicated their expression in the nematode. Stage-wise exploration of M. incognita miRNAs has not been carried out before and this work presents information on common and stage-specific miRNAs of the root-knot nematode.

  18. Attentional control underlies the perceptual load effect: Evidence from voxel-wise degree centrality and resting-state functional connectivity.

    Science.gov (United States)

    Yin, Shouhang; Liu, Lu; Tan, Jinfeng; Ding, Cody; Yao, Dezhong; Chen, Antao

    2017-10-24

    The fact that interference from peripheral distracting information can be reduced in high perceptual load tasks has been widely demonstrated in previous research. The modulation from the perceptual load is known as perceptual load effect (PLE). Previous functional magnetic resonance imaging (fMRI) studies on perceptual load have reported the brain areas implicated in attentional control. To date, the contribution of attentional control to PLE and the relationship between the organization of functional connectivity and PLE are still poorly understood. In the present study, we used resting-state fMRI to explore the association between the voxel-wise degree centrality (DC) and PLE in an individual differences design and further investigated the potential resting-state functional connectivity (RSFC) contributing to individual's PLE. DC-PLE correlation analysis revealed that PLE was positively associated with the right middle temporal visual area (MT)-one of dorsal attention network (DAN) nodes. Furthermore, the right MT functionally connected to the conventional DAN and the RSFCs between right MT and DAN nodes were also positively associated with individual difference in PLE. The results suggest an important role of attentional control in perceptual load tasks and provide novel insights into the understanding of the neural correlates underlying PLE. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

  19. Evaluation of School Uniform Policy in Turkey: A Case Study

    Science.gov (United States)

    Cinoglu, Mustafa

    2014-01-01

    The purpose of this study is to evaluate the results of current school uniform policies according to views of stakeholders. Descriptive case study method was used for this study to understand the concerns of the stakeholders about school uniforms. Data was collected through interviews with stakeholders and also reviewing the documents in TOKI…

  20. A study of combined evaluation of suppliers based on correlation

    Directory of Open Access Journals (Sweden)

    Heting Qiu

    2013-03-01

    Full Text Available Purpose: The Selection of logistics service providers is an important issue in supply chain management. But different evaluation methods may lead to different results, which could cause inconsistent conclusions. This paper makes use of a new perspective to combine with a variety of methods to eliminate the deviation of different single evaluation methods. Design/methodology/approach: This paper expounds the application of the combined evaluation method based on correlation. Entropy method, factor analysis, grey colligation evaluation and AHP have been used for research. Findings: According to the evaluate result, the ranking of suppliers obtained by each method have obvious differences. The result shows that combined evaluation method can eliminate the deviation of different single evaluation methods. Originality/value: The combined evaluation method makes up for the defects of single evaluation methods and obtains a result that is more stable and creditable with smaller deviation. This study can provide the enterprise leaders with more scientific method to select their cooperative companies. 

  1. Making program evaluation activities family-centered: a qualitative study.

    Science.gov (United States)

    Moreau, Katherine A; Cousins, J Bradley

    2014-01-01

    This study explored ways in which program evaluation activities in pediatric rehabilitation settings can become congruent with family-centered service (FCS) philosophy. Two Canadian pediatric rehabilitation centers participated in this study, which included focus groups with staff members and interviews with parents. Participants identified seven ways in which program evaluation practices could be made congruent with FCS. Suggestions included: (a) the inclusion of a diverse group of program recipients, (b) the use of processes that facilitate family involvement, (c) the recruitment of family champions, (d) the involvement of families in program development, (e) the establishment of evaluations that are relevant to families (f) the development of center-wide statements about family involvement in evaluation and (g) the compensation of families for their active participation in evaluation. For program evaluation practices to be useful and relevant, they should be improved and made consistent with FCS philosophy. Those evaluating pediatric rehabilitation programs need to use approaches and activities that respect the needs, characteristics, cultures and diversity of the program recipients. Such actions will help to improve the quality of care provided, the nature of program evaluation activities, as well as the overall level of FCS in pediatric rehabilitation settings.

  2. DETERMINATION OF IMPORTANCE EVALUATION FOR THE SUBSURFACE EXPORATORY STUDIES FACILITY

    Energy Technology Data Exchange (ETDEWEB)

    W.J. Clark

    1999-06-28

    This Determination of Importance Evaluation (DIE) applies to the Subsurface Exploratory Studies Facility (ESF), encompassing the Topopah Spring (TS) Loop from Station 0+00 meters (m) at the North Portal to breakthrough at the South Portal (approximately 78+77 m), the Enhanced Characterization of the Repository Block (ECRB) East-West Cross Drift Starter Tunnel (to approximate ECRB Station 0+26 m), and ancillary test and operation support areas in the TS Loop. This evaluation applies to the construction, operation, and maintenance of these excavations. A more detailed description of these items is provided in Section 6.0. Testing activities are not evaluated in this DIE. Certain construction activities with respect to testing activities are evaluated; but the testing activities themselves are not evaluated. The DIE for ESF Subsurface Testing Activities (BAJ3000000-01717-2200-00011 Rev 01) (CRWMS M&O 1998a) evaluates Subsurface ESF Testing activities. The construction, operation, and maintenance of the TS Loop niches and alcove slot cuts is evaluated herein and is also discussed in CRWMS M&O 1998a. The construction, operation, and maintenance of the Busted Butte subsurface test area in support of the Unsaturated Zone (UZ) Transport Test is evaluated in CRWMS M&O 1998a. Potential test-to-test interference and the waste isolation impacts of testing activities are evaluated in the ESF Subsurface Testing Activities DIE and other applicable evaluation(s) for the Job Package (JP), Test Planning Package (TPP), and/or Field Work Package (FWP). The objectives of this DIE are to determine whether the Subsurface ESF TS Loop and associated excavations, including activities associated with their construction and operation, potentially impact site characterization testing or the waste isolation capabilities of the site. Controls needed to limit any potential impacts are identified. The validity and veracity of the individual tests, including data collection, are the responsibility

  3. Effect of Paecilomyces fumosoroseus (Wise) Brown and Smith(Ascomycota: Hypocreales) alone or in combination with diatomaceous earth against Tribolium confusum Jacquelin du Val (Coleoptera:Tenebrionidae) and Ephestia kuehniella Zeller (Lepidoptera: Pyralidae)

    DEFF Research Database (Denmark)

    Michalaki, M P; Athanassiou, C G; Steenberg, Tove

    2007-01-01

    The insecticidal eVect of the entomopathogenic fungus Paecilomyces fumosoroseus (Wise) Brown and Smith (Ascomycota: Hypocreales) was evaluated against adults and larvae of the confused Xour beetle, Tribolium confusum Jacquelin du Val (Coleoptera: Tenebrionidae) and larvae of the Mediterranean Xour...

  4. Sustaining and Improving Study Abroad Experiences Through Comparative Evaluation.

    Science.gov (United States)

    Johanson, Linda S

    Researchers have related participation in study abroad experiences to many positive outcomes for nursing students; however, educators are faced with the task of not only developing meaningful study abroad opportunities but sustaining and improving them as well. Educators can evaluate repeat study abroad programs by comparing experiences, looking for trends, and conjecturing rationales. To illustrate this process, an example of a study abroad opportunity that has been repeated over 11 years is presented. The first six years have been compared to the most recent five years, revealing three categories of change for evaluation and the resulting course improvements.

  5. Measuring the effect of Choosing Wisely: an integrated framework to assess campaign impact on low-value care.

    Science.gov (United States)

    Bhatia, R Sacha; Levinson, Wendy; Shortt, Samuel; Pendrith, Ciara; Fric-Shamji, Elana; Kallewaard, Marjon; Peul, Wilco; Veillard, Jeremy; Elshaug, Adam; Forde, Ian; Kerr, Eve A

    2015-08-01

    The Choosing Wisely campaign began in the USA in 2012 to encourage physicians and patients to discuss inappropriate and potentially harmful tests, treatments and procedures. Since its inception, the campaign has grown substantially and has been adopted by 12 countries around the world. Of great interest to countries implementing the campaign, is the effectiveness of Choosing Wisely to reduce overutilisation. This article presents an integrated measurement framework that may be used to assess the impact of a Choosing Wisely campaign on physician and provider awareness and attitudes on low-value care, provider practice behaviour and overuse of low-value services. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. A layer-wise MITC9 finite element for the free-vibration analysis of plates with piezo-patches

    Directory of Open Access Journals (Sweden)

    Maria Cinefra

    2015-04-01

    Full Text Available The present article considers the free-vibration analysis of plate structures with piezoelectric patches by means of a plate finite element with variable through-the-thickness layer-wise kinematic. The refined models used are derived from Carrera’s Unified Formulation (CUF and they permit the vibration modes along the thickness to be accurately described. The finite-element method is employed and the plate element implemented has nine nodes, and the mixed interpolation of tensorial component (MITC method is used to contrast the membrane and shear locking phenomenon. The related governing equations are derived from the principle of virtual displacement, extended to the analysis of electromechanical problems. An isotropic plate with piezoelectric patches is analyzed, with clamped-free boundary conditions and subjected to open- and short-circuit configurations. The results, obtained with different theories, are compared with the higher-order type solutions given in the literature. The conclusion is reached that the plate element based on the CUF is more suitable and efficient compared to the classical models in the study of multilayered structures embedding piezo-patches.

  7. On the mid-infrared variability of candidate eruptive variables (exors): A comparison between Spitzer and WISE data

    Energy Technology Data Exchange (ETDEWEB)

    Antoniucci, S.; Giannini, T.; Li Causi, G.; Lorenzetti, D., E-mail: simone.antoniucci@oa-roma.inaf.it, E-mail: teresa.giannini@oa-roma.inaf.it, E-mail: gianluca.licausi@oa-roma.inaf.it, E-mail: dario.lorenzetti@oa-roma.inaf.it [INAF-Osservatorio Astronomico di Roma, via Frascati 33, I-00040 Monte Porzio (Italy)

    2014-02-10

    Aiming to statistically study the variability in the mid-IR of young stellar objects, we have compared the 3.6, 4.5, and 24 μm Spitzer fluxes of 1478 sources belonging to the C2D (Cores to Disks) legacy program with the WISE fluxes at 3.4, 4.6, and 22 μm. From this comparison, we have selected a robust sample of 34 variable sources. Their variations were classified per spectral Class (according to the widely accepted scheme of Class I/flat/II/III protostars), and per star forming region. On average, the number of variable sources decreases with increasing Class and is definitely higher in Perseus and Ophiuchus than in Chamaeleon and Lupus. According to the paradigm Class ≡ Evolution, the photometric variability can be considered to be a feature more pronounced in less evolved protostars, and, as such, related to accretion processes. Moreover, our statistical findings agree with the current knowledge of star formation activity in different regions. The 34 selected variables were further investigated for similarities with known young eruptive variables, namely the EXors. In particular, we analyzed (1) the shape of the spectral energy distribution, (2) the IR excess over the stellar photosphere, (3) magnitude versus color variations, and (4) output parameters of model fitting. This first systematic search for EXors ends up with 11 bona fide candidates that can be considered as suitable targets for monitoring or future investigations.

  8. Precommitting to choose wisely about low-value services: a stepped wedge cluster randomised trial.

    Science.gov (United States)

    Kullgren, Jeffrey Todd; Krupka, Erin; Schachter, Abigail; Linden, Ariel; Miller, Jacquelyn; Acharya, Yubraj; Alford, James; Duffy, Richard; Adler-Milstein, Julia

    2017-10-24

    Little is known about how to discourage clinicians from ordering low-value services. Our objective was to test whether clinicians committing their future selves (ie, precommitting) to follow Choosing Wisely recommendations with decision supports could decrease potentially low-value orders. We conducted a 12-month stepped wedge cluster randomised trial among 45 primary care physicians and advanced practice providers in six adult primary care clinics of a US community group practice.Clinicians were invited to precommit to Choosing Wisely recommendations against imaging for uncomplicated low back pain, imaging for uncomplicated headaches and unnecessary antibiotics for acute sinusitis. Clinicians who precommitted received 1-6 months of point-of-care precommitment reminders as well as patient education handouts and weekly emails with resources to support communication about low-value services.The primary outcome was the difference between control and intervention period percentages of visits with potentially low-value orders. Secondary outcomes were differences between control and intervention period percentages of visits with possible alternate orders, and differences between control and 3-month postintervention follow-up period percentages of visits with potentially low-value orders. The intervention was not associated with a change in the percentage of visits with potentially low-value orders overall, for headaches or for acute sinusitis, but was associated with a 1.7% overall increase in alternate orders (p=0.01). For low back pain, the intervention was associated with a 1.2% decrease in the percentage of visits with potentially low-value orders (p=0.001) and a 1.9% increase in the percentage of visits with alternate orders (p=0.007). No changes were sustained in follow-up. Clinician precommitment to follow Choosing Wisely recommendations was associated with a small, unsustained decrease in potentially low-value orders for only one of three targeted conditions and

  9. Comparative evaluation of shear bond strength of two self-etching adhesives (sixth and seventh generation on dentin of primary and permanent teeth: An in vitro study

    Directory of Open Access Journals (Sweden)

    Yaseen S

    2009-03-01

    Full Text Available Aim: The present study was undertaken to compare and evaluate shear bond strength of two self-etching adhesives (sixth and seventh generation on dentin of primary and permanent teeth. Materials and Methods: Flat dentin surface of 64 human anterior teeth (32 primary and 32 permanent divided into four groups of 16 each. Groups A and C were treated with Contax (sixth generation, while groups B and D were treated with Clearfil S3 (seventh generation. A teflon mold was used to build the composite (Filtek Z-350 cylinders on the dentinal surface of all the specimens. Shear bond strength was tested for all the specimens with an Instron Universal Testing Machine. Data were statistically analyzed using one-way ANOVA for multiple group comparison, followed by student′s unpaired ′t′ test for group-wise comparison. Results: There was no statistically significant difference in shear bond strength among the study groups except that primary teeth bonded with Contax exhibited significantly lesser shear bond strength than permanent teeth bonded with Clearfil S3. Conclusion: This study revealed that Clearfil S3 could be of greater advantage in pediatric dentistry than Contax because of its fewer steps and better shear bond strength in dentin of both primary and permanent teeth.

  10. NuSTAR observations of WISE J1036+0449, a galaxy at z ∼ 1 obscured by hot dust

    DEFF Research Database (Denmark)

    Ricci, C.; Assef, R. J.; Stern, D.

    2017-01-01

    Hot dust-obscured galaxies (hot DOGs), selected from Wide-Field Infrared Survey Explorer’s all-sky infrared survey, host some of the most powerful active galactic nuclei known and may represent an important stage in the evolution of galaxies. Most known hot DOGs are located at z > 1.5, due in part...... to a strong bias against identifying them at lower redshift related to the selection criteria. We present a new selection method that identifies 153 hot DOG candidates at z ~ 1, where they are significantly brighter and easier to study. We validate this approach by measuring a redshift z = 1.009 and finding...... a spectral energy distribution similar to that of higher-redshift hot DOGs for one of these objects, WISE J1036+0449 (LBol ≃ 8 × 1046 erg s−1). We find evidence of a broadened component in Mg II, which would imply a black hole mass of MBH ≃ 2 × 108 M⊙ and an Eddington ratio of λEdd ≃ 2.7. WISE J1036...

  11. Improved estimation of parametric images of cerebral glucose metabolic rate from dynamic FDG-PET using volume-wise principle component analysis

    Science.gov (United States)

    Dai, Xiaoqian; Tian, Jie; Chen, Zhe

    2010-03-01

    Parametric images can represent both spatial distribution and quantification of the biological and physiological parameters of tracer kinetics. The linear least square (LLS) method is a well-estimated linear regression method for generating parametric images by fitting compartment models with good computational efficiency. However, bias exists in LLS-based parameter estimates, owing to the noise present in tissue time activity curves (TTACs) that propagates as correlated error in the LLS linearized equations. To address this problem, a volume-wise principal component analysis (PCA) based method is proposed. In this method, firstly dynamic PET data are properly pre-transformed to standardize noise variance as PCA is a data driven technique and can not itself separate signals from noise. Secondly, the volume-wise PCA is applied on PET data. The signals can be mostly represented by the first few principle components (PC) and the noise is left in the subsequent PCs. Then the noise-reduced data are obtained using the first few PCs by applying 'inverse PCA'. It should also be transformed back according to the pre-transformation method used in the first step to maintain the scale of the original data set. Finally, the obtained new data set is used to generate parametric images using the linear least squares (LLS) estimation method. Compared with other noise-removal method, the proposed method can achieve high statistical reliability in the generated parametric images. The effectiveness of the method is demonstrated both with computer simulation and with clinical dynamic FDG PET study.

  12. Stimulus-Related Independent Component and Voxel-Wise Analysis of Human Brain Activity during Free Viewing of a Feature Film

    Science.gov (United States)

    Lahnakoski, Juha M.; Salmi, Juha; Jääskeläinen, Iiro P.; Lampinen, Jouko; Glerean, Enrico; Tikka, Pia; Sams, Mikko

    2012-01-01

    Understanding how the brain processes stimuli in a rich natural environment is a fundamental goal of neuroscience. Here, we showed a feature film to 10 healthy volunteers during functional magnetic resonance imaging (fMRI) of hemodynamic brain activity. We then annotated auditory and visual features of the motion picture to inform analysis of the hemodynamic data. The annotations were fitted to both voxel-wise data and brain network time courses extracted by independent component analysis (ICA). Auditory annotations correlated with two independent components (IC) disclosing two functional networks, one responding to variety of auditory stimulation and another responding preferentially to speech but parts of the network also responding to non-verbal communication. Visual feature annotations correlated with four ICs delineating visual areas according to their sensitivity to different visual stimulus features. In comparison, a separate voxel-wise general linear model based analysis disclosed brain areas preferentially responding to sound energy, speech, music, visual contrast edges, body motion and hand motion which largely overlapped the results revealed by ICA. Differences between the results of IC- and voxel-based analyses demonstrate that thorough analysis of voxel time courses is important for understanding the activity of specific sub-areas of the functional networks, while ICA is a valuable tool for revealing novel information about functional connectivity which need not be explained by the predefined model. Our results encourage the use of naturalistic stimuli and tasks in cognitive neuroimaging to study how the brain processes stimuli in rich natural environments. PMID:22496909

  13. Stimulus-related independent component and voxel-wise analysis of human brain activity during free viewing of a feature film.

    Directory of Open Access Journals (Sweden)

    Juha M Lahnakoski

    Full Text Available Understanding how the brain processes stimuli in a rich natural environment is a fundamental goal of neuroscience. Here, we showed a feature film to 10 healthy volunteers during functional magnetic resonance imaging (fMRI of hemodynamic brain activity. We then annotated auditory and visual features of the motion picture to inform analysis of the hemodynamic data. The annotations were fitted to both voxel-wise data and brain network time courses extracted by independent component analysis (ICA. Auditory annotations correlated with two independent components (IC disclosing two functional networks, one responding to variety of auditory stimulation and another responding preferentially to speech but parts of the network also responding to non-verbal communication. Visual feature annotations correlated with four ICs delineating visual areas according to their sensitivity to different visual stimulus features. In comparison, a separate voxel-wise general linear model based analysis disclosed brain areas preferentially responding to sound energy, speech, music, visual contrast edges, body motion and hand motion which largely overlapped the results revealed by ICA. Differences between the results of IC- and voxel-based analyses demonstrate that thorough analysis of voxel time courses is important for understanding the activity of specific sub-areas of the functional networks, while ICA is a valuable tool for revealing novel information about functional connectivity which need not be explained by the predefined model. Our results encourage the use of naturalistic stimuli and tasks in cognitive neuroimaging to study how the brain processes stimuli in rich natural environments.

  14. Span-wise correlations of pressures on a square cylinder – simulated using the SMoM turbulence model

    DEFF Research Database (Denmark)

    Johansson, Jens; Nielsen, M. P.

    2013-01-01

    The uniform flow around a square cylinder at Reynolds number 1e5 is simulated in a three dimensional domain by means of the newly developed Self-induced angular Moment Method, SMoM, turbulence model. The span-wise correlation of surface pressures are compared to reported experimental findings...... to validate the three-dimensional capabilities of the SMoM model. Three different cylinder lengths; 2, 6, and 10 times the cylinder side-length, is simulated and the change in global force coefficients are reported. The SMoM model is found to provide improved predictions of span-wise surface pressure...

  15. Impact Evaluation Study for Institution Strengthening of Social Food Distribution

    Directory of Open Access Journals (Sweden)

    Budiman Notoatmojo

    2016-03-01

    Full Text Available The general objectives of this study were to evaluate whether the implementation of activities for strengthening LDPM could achieve the expected goals, to evaluate whether the LDPM strengthening activities had a positive impact. The study analysis used was descriptive, comparison, and financial analysis. The results of this study have shown that LDPM farmers’ income have increased significantly, and the Gapoktan as LPDM farmers’ institution has been significantly developing as a Bulog function in procuring grain paddy from farmers during peak harvest and distributing rice to stabilize the price of rice during the limited rice in the market.

  16. Evaluation of Emotional Literacy Activities: A Phenomenological Study

    Science.gov (United States)

    Oksuz, Yucel

    2016-01-01

    The present study aims to evaluate impact of the emotional literacy activities through participant student's experiences. Emotional literacy activities, including social-emotional skills Goleman's emotional intelligence and Fapuel's emotional literacy model designed and conducted for 2 months on primary school students, who study in 4th grade. The…

  17. Evaluating QR Code Case Studies Using a Mobile Learning Framework

    Science.gov (United States)

    Rikala, Jenni

    2014-01-01

    The aim of this study was to evaluate the feasibility of Quick Response (QR) codes and mobile devices in the context of Finnish basic education. The feasibility was analyzed through a mobile learning framework, which includes the core characteristics of mobile learning. The study is part of a larger research where the aim is to develop a…

  18. Evaluating Mixed Research Studies: A Mixed Methods Approach

    Science.gov (United States)

    Leech, Nancy L.; Dellinger, Amy B.; Brannagan, Kim B.; Tanaka, Hideyuki

    2010-01-01

    The purpose of this article is to demonstrate application of a new framework, the validation framework (VF), to assist researchers in evaluating mixed research studies. Based on an earlier work by Dellinger and Leech, a description of the VF is delineated. Using the VF, three studies from education, health care, and counseling fields are…

  19. A block-wise approximate parallel implementation for ART algorithm on CUDA-enabled GPU.

    Science.gov (United States)

    Fan, Zhongyin; Xie, Yaoqin

    2015-01-01

    Computed tomography (CT) has been widely used to acquire volumetric anatomical information in the diagnosis and treatment of illnesses in many clinics. However, the ART algorithm for reconstruction from under-sampled and noisy projection is still time-consuming. It is the goal of our work to improve a block-wise approximate parallel implementation for the ART algorithm on CUDA-enabled GPU to make the ART algorithm applicable to the clinical environment. The resulting method has several compelling features: (1) the rays are allotted into blocks, making the rays in the same block parallel; (2) GPU implementation caters to the actual industrial and medical application demand. We test the algorithm on a digital shepp-logan phantom, and the results indicate that our method is more efficient than the existing CPU implementation. The high computation efficiency achieved in our algorithm makes it possible for clinicians to obtain real-time 3D images.

  20. Understanding sustainable seafood consumption behavior: an examination of the Ocean Wise (OW initiative in British Columbia

    Directory of Open Access Journals (Sweden)

    Katherine M. Dolmage

    2016-06-01

    Full Text Available Sustainable seafood labeling programs have been developed as one of several efforts to address the current dire trends in fish stocks. The Ocean Wise (OW program, started at the Vancouver Aquarium (Canada, works with restaurateurs and suppliers to simplify sustainable purchasing decisions. By aiding restaurateurs with responsible purchasing, OW hopes to shift demand to sustainable seafood products. OW has grown in numbers and spread across Canada quickly; we examine the factors associated with individual and organizational decisions to participate in the program, including personal, business, and program-related factors. These factors were examined in relation to OW membership by Vancouver restaurateurs. Results show that restaurateurs with greater knowledge of seafood issues and restaurants with greater commitment to a range of green initiatives are more likely to participate in the OW program. By focusing efforts on education and incorporating a range of green values into marketing, OW can maximize their limited resources to grow membership.

  1. IMAGE ENCRYPTION IN BLOCK-WISE WITH MULTIPLE CHAOTIC MAPS FOR PERMUTATION AND DIFFUSION

    Directory of Open Access Journals (Sweden)

    T. Gopalakrishnan

    2016-02-01

    Full Text Available This paper presents an efficient block-wise image encryption method based on multiple chaotic maps. The image is divided into four overlapping blocks and each block is permutated with Cat map and its parameters are controlled by Henon map using multiple keys. Due to overlapping division of blocks, it produces effect of double permutation in the middle portion of overlapped image in single permutation itself. For diffusion, the whole image is divided into four non-overlapping blocks and diffused with logistic map. Each block pixel values were completely modified in the diffusion process in order to avoid known-plaintext and chosen-plaintext attacks. For each division of blocks different keys were selected for both permutation and diffusion process in the proposed method. The simulation results of several statistical analysis shows that the proposed cryptosystem is efficient and highly secured

  2. Analysis of family-wise error rates in statistical parametric mapping using random field theory.

    Science.gov (United States)

    Flandin, Guillaume; Friston, Karl J

    2017-11-01

    This technical report revisits the analysis of family-wise error rates in statistical parametric mapping-using random field theory-reported in (Eklund et al. []: arXiv 1511.01863). Contrary to the understandable spin that these sorts of analyses attract, a review of their results suggests that they endorse the use of parametric assumptions-and random field theory-in the analysis of functional neuroimaging data. We briefly rehearse the advantages parametric analyses offer over nonparametric alternatives and then unpack the implications of (Eklund et al. []: arXiv 1511.01863) for parametric procedures. Hum Brain Mapp, 2017. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. © 2017 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc.

  3. Matrix multiplication operations using pair-wise load and splat operations

    Science.gov (United States)

    Eichenberger, Alexandre E.; Gschwind, Michael K.; Gunnels, John A.; Salapura, Valentina

    2017-03-21

    Mechanisms for performing a matrix multiplication operation are provided. A vector load operation is performed to load a first vector operand of the matrix multiplication operation to a first target vector register. A pair-wise load and splat operation is performed to load a pair of scalar values of a second vector operand and replicate the pair of scalar values within a second target vector register. An operation is performed on elements of the first target vector register and elements of the second target vector register to generate a partial product of the matrix multiplication operation. The partial product is accumulated with other partial products and a resulting accumulated partial product is stored. This operation may be repeated for a second pair of scalar values of the second vector operand.

  4. Application of Story-wise Shear Building Identification Method to Actual Ambient Vibration

    Directory of Open Access Journals (Sweden)

    Kohei eFujita

    2015-02-01

    Full Text Available A sophisticated and smart story stiffness System Identification (SI method for a shear building model is applied to a full-scale building frame subjected to micro-tremors. The advantageous and novel feature is that not only the modal parameters, such as natural frequencies and damping ratios, but also the physical model parameters, such as story stiffnesses and damping coefficients, can be identified using micro-tremors. While the building responses to earthquake ground motions are necessary in the previous SI method, it is shown in this paper that the micro-tremor measurements in a full-scale 5 story building frame can be used for identification within the same framework. The SI using micro-tremor measurements leads to the enhanced usability of the previously proposed story-wise shear building identification method. The degree of ARX models and cut-off frequencies of band-pass filter are determined to derive reliable results.

  5. Circumstellar dust, PAHs and stellar populations in early-type galaxies: insights from GALEX and WISE

    Science.gov (United States)

    Simonian, Gregory V.; Martini, Paul

    2017-02-01

    A majority of early-type galaxies contain interstellar dust, yet the origin of this dust, and why the dust sometimes exhibits unusual polycyclic aromatic hydrocarbon (PAH) ratios, remains a mystery. If the dust is internally produced, it likely originates from the large number of asymptotic giant branch stars associated with the old stellar population. We present GALEX and WISE elliptical aperture photometry of ˜310 early-type galaxies with Spitzer mid-infrared spectroscopy and/or ancillary data from ATLAS3D, to characterize their circumstellar dust and the shape of the radiation field that illuminates the interstellar PAHs. We find that circumstellar dust is ubiquitous in early-type galaxies, which indicates some tension between stellar population age estimates and models for circumstellar dust production in very old stellar populations. We also use dynamical masses from ATLAS3D to show that WISE W1 (3.4 μm) mass-to-light ratios are consistent with the initial mass function variation found by previous work. While the stellar population differences in early-type galaxies correspond to a range of radiation field shapes incident upon the diffuse dust, the ratio of the ionization-sensitive 7.7 μm/11.3 μm PAH feature does not correlate with the shape of the radiation field, nor to variations with the size-sensitive 11.3 μm/17 μm ratio. The 7.7 μm/11.3 μm PAH ratio does tend to be smaller in galaxies with proportionally greater H2 emission, which is evidence that processing of primarily smaller grains by shocks is responsible for the unusual ratios, rather than substantial differences in the overall PAH size or ionization distribution.

  6. Toward a sustainable and wise healthcare approach: potential contributions from hospital Internal Medicine Departments to reducing inappropriate medical spending

    Directory of Open Access Journals (Sweden)

    Roberto Nardi

    2013-04-01

    Full Text Available All countries are facing the question of how to maintain quality of care with shrinking health budgets, in the presence of a persistent increase in life expectancy, and with a significant growing demand for health care from aging populations and chronically ill patients. Current implementation of legislative measures is largely presented as a cost-cutting policy. With this political approach, there is a risk of services and the number of hospital beds being drastically reduced, mainly to detriment of the most vulnerable groups of the population and without considering the results obtained by each regional healthcare organization according to explicit evaluation markers. In our Scientific Society of Internal Medicine (the Federation of Associations of Hospital Doctors on Internal Medicine, FADOI, we want to support good medical practice because essential medicine is still a goal to be achieved throughout medical hospital care. We are looking for original ways to implement a sustainable and frugal hospital Internal Medicine policy by searching for wise and efficient clinical methodology to be applied in the care of patients admitted to internal medicine wards according to their real needs. We firmly believe that reinforcing a common agenda between medicine and public health, and sharing a common vision among professionals and decision makers in the planning of care, may be the greatest opportunity for any every health care reform. The future of the health care system cannot be restricted to mere cost reduction, but should aim to deliver better health care in relation to the money spent. Even in this period of austerity, new opportunities can still be found and doctors must lead efforts to meet this challenge.

  7. Pharmacognostical study and phytochemical evaluation of brown seaweed Sargassum wightii

    Directory of Open Access Journals (Sweden)

    Jeyaraman Amutha Iswarya Devi

    2013-10-01

    Full Text Available Objective: To explore the pharmacognostical and phytochemical properties of Sargassum wightii. Methods: The qualitative microscopy, phytochemical screening, physicochemical evaluation and fluorescence analysis of the plant were carried out according to the standard procedure recommended in the WHO guidelines. Results: Macroscopic study showed that plants were dark brown, 20-30 cm in height, leaves were 5-8 cm length, shape: linear to ovate, apex: midrib in conspicuous and having the entire, serrate margin. Microscopic evaluation of the transverse section of the leaf, stem, air bladder, receptacles showed the presence of epidermis layer followed by thick cuticle, conducting strand, mesophyll and possessed antheridia or oogonia at the swollen terminal portions. The different extracts of Sargassum wightii showed the presence of steroids, alkaloids, phenolic compounds, saponins and flavonoids with varied degree. Conclusions: Various pharmacognostical parameters evaluated in this study help in the identification and standardization of the of the seaweed Sargassum wightii

  8. Providing the Psychosocial Benefits of Mentoring to Women in STEM: "Career"WISE as an Online Solution

    Science.gov (United States)

    Dawson, Amy E.; Bernstein, Bianca L.; Bekki, Jennifer M.

    2015-01-01

    This chapter outlines the psychosocial aspects of mentoring that help women combat the barriers they commonly face in science, technology, engineering, and mathematics (STEM). The authors describe the "Career"WISE online resilience training and how it can address the shortage of effective mentors and role models who have been shown to…

  9. Soil property estimates for the Upper Tana river catchment, Kenya, derived from SOTER and WISE (ver.1.1)

    NARCIS (Netherlands)

    Batjes, N.H.

    2013-01-01

    This data set describes a harmonized set of soil property estimates for the Upper Tana river catchment, Kenya. The data set was derived from the 1:250 000 scale Soil and Terrain Database for the Upper Tana (SOTER_UT, ver. 1.1; Dijkshoorn et al. 2011) and the ISRIC-WISE soil profile database, using

  10. Soil property estimates for Tunisia derived from SOTER and WISE (SOTWIS-Tunisia, ver. 1.0)

    NARCIS (Netherlands)

    Batjes, N.H.

    2014-01-01

    This datasets describes a harmonized set of soil property estimates for Tunisia. It has been derived from the 1:1 million scale Soil and Terrain Database for the country (SOTER_TN, ver. 1.0) and the ISRIC-WISE soil profile database, using standardized taxonomy-based pedotransfer (taxotransfer)

  11. An overview of 2016 WISE Urban Summer Observation Campaign (WUSOC 2016) in the Seoul metropolitan area of South Korea

    Science.gov (United States)

    Jung, Jae-Won; Kim, Sang-Woo; Shim, Jae-Kwan; Kwak, Kyung-Hwan

    2017-04-01

    The Weather Information Service Engine (WISE), launched project of the Korea Meteorological Administration (KMA), aims to operate the urban meteorological observation network from 2012 to 2019 and to test and operate the application weather service (e.g., flash flood, road weather, city ecology, city microclimate, dispersion of hazardous substance etc.) in 2019 through the development of Advanced Storm-scale Analysis Prediction System(ASAPS) for the production of storm-scale hazard weather monitoring and prediction system. The WISE institute has completed construction of 31 urban meteorological observation cities in Seoul metropolitan area and has built a real-time test operation and verification system by improving the ASAPS that produces 1 km and 6 hour forecast information based on the 5 km forecast information of KMA. Field measurements of 2016 WISE Urban Summer Observation Campaign (WUSOC 2016) was conducted in the Seoul metropolitan area of South Korea from August 22 to October 14, 2016. Involving over 70 researchers from more than 12 environmental and atmospheric science research groups in South Korea, WUSOC2016 focused on special observations, severe rain storm observations using mobile observation car and radiosonde, wind profile observations using Wind Doppler Lidar and radiosonde, etc., around the Seoul metropolitan area. WUSOC2016 purpose at data quality control, accuracy verification, usability check, and quality improvement of ASAPS at observation stations constructed in WISE. In addition, we intend to contribute to the activation of urban fusion weather research and risk weather research through joint observation and data sharing.

  12. MSClust: a tool for unsupervised mass spectra extraction of chromatography-mass spectrometry ion-wise aligned data

    NARCIS (Netherlands)

    Tikunov, Y.M.; Laptenok, S.; Hall, R.D.; Bovy, A.G.; Vos, de C.H.

    2012-01-01

    Mass peak alignment (ion-wise alignment) has recently become a popular method for unsupervised data analysis in untargeted metabolic profiling. Here we present MSClust—a software tool for analysis GC–MS and LC–MS datasets derived from untargeted profiling. MSClust performs data reduction using

  13. Phase-wise enhanced voltage support from electric vehicles in a Danish low-voltage distribution grid

    DEFF Research Database (Denmark)

    Knezovic, Katarina; Marinelli, Mattia

    2016-01-01

    while the energy losses are not notably increased. Further on, since the control is voltage dependent, provided reactive power is unequal among the phases leading to greater support on heavily loaded phases and decreased unbalances caused by residential consumption. Hence, implementation of such a phase-wise...

  14. National Church Panel on Strip Mining and the Energy Crisis (Clinch Valley College, Wise, Virginia, March 14-16, 1974).

    Science.gov (United States)

    1974

    This report of the National Church Panel is designed to assist churches and other institutions and individuals in recognizing the current and future issues of national energy policy, as it relates to government and corporations. The report is based on public hearings on strip mining and the energy crisis held at Clinch Valley College, Wise,…

  15. Longitudinal interpolation of parameters characterizing channel geometry by piece-wise polynomial and universal kriging methods: effect on flow modeling

    Science.gov (United States)

    Sanders, Brett F.; Chrysikopoulos, Constantios V.

    Channel geometry often is described by a set of longitudinally varying parameters measured at a set of survey stations. To support flow modeling at arbitrary resolution, three methods of parameter interpolation are described including piece-wise linear interpolation, monotone piece-wise-cubic Hermitian interpolation, and universal kriging. The latter gives parameter estimates that minimize the mean square error of the interpolator, and therefore can be used as a standard against which the accuracy of polynomial methods can be assessed. Based on the application of these methods to a dataset describing cross-sectional properties at 283 stations, piece-wise linear interpolation gives parameter estimates that closely track universal kriging estimates and therefore this method is recommended for routine modeling purposes. Piece-wise-cubic interpolation gives parameter estimates that do not track as well. Differences between cubic and kriging estimates were found to be 2-10 times larger than differences between linear and kriging parameter estimates. In the context of one-dimensional flow modeling, the sensitivity of steady state water level predictions to the channel bed interpolator is comparable to a 5% change in the Manning coefficient.

  16. IMPLICATIONS FOR ASYMMETRY, NONPROPORTIONALITY, AND HETEROGENEITY IN BRAND SWITCHING FROM PIECE-WISE EXPONENTIAL MIXTURE HAZARD MODELS

    NARCIS (Netherlands)

    WEDEL, M; KAMAKURA, WA; DESARBO, WS; TERHOFSTEDE, F

    1995-01-01

    The authors develop a class of mixtures of piece-wise exponential hazard models for the analysis of brand switching behavior. The models enable the effects of marketing variables to change nonproportionally over time and can, simultaneously, be used to identify segments among which switching and

  17. Tilting at Windmills? Judge Justine Wise Polier and a History of Justice and Education in New York City

    Science.gov (United States)

    de Forest, Jennifer

    2009-01-01

    Judge Justine Wise Polier's judicial career illuminates the interconnections between the history of the New York City public schools and the Children's Courts, making clear that for many children who found themselves in trouble, justice and education were intertwined. Critics of the children's courts have argued that they were flawed from their…

  18. Pair-Wise Trajectory Management-Oceanic (PTM-O) . [Concept of Operations—Version 3.9

    Science.gov (United States)

    Jones, Kenneth M.

    2014-01-01

    This document describes the Pair-wise Trajectory Management-Oceanic (PTM-O) Concept of Operations (ConOps). Pair-wise Trajectory Management (PTM) is a concept that includes airborne and ground-based capabilities designed to enable and to benefit from, airborne pair-wise distance-monitoring capability. PTM includes the capabilities needed for the controller to issue a PTM clearance that resolves a conflict for a specific pair of aircraft. PTM avionics include the capabilities needed for the flight crew to manage their trajectory relative to specific designated aircraft. Pair-wise Trajectory Management PTM-Oceanic (PTM-O) is a regional specific application of the PTM concept. PTM is sponsored by the National Aeronautics and Space Administration (NASA) Concept and Technology Development Project (part of NASA's Airspace Systems Program). The goal of PTM is to use enhanced and distributed communications and surveillance along with airborne tools to permit reduced separation standards for given aircraft pairs, thereby increasing the capacity and efficiency of aircraft operations at a given altitude or volume of airspace.

  19. The Evaluation of Study Success between Online Study and Classroom Study Environment

    Directory of Open Access Journals (Sweden)

    Singkhamfu Phudinan

    2016-01-01

    Full Text Available Online study has increasingly become more attractive to students at university level due to convenience access to their instructors and to study resources. This study has developed online social network for study. It proposes to provide lesson content availability, past lecture, by sending online study lesson media to students’ mobile phone or tablet. Approximately 85 undergraduate software engineering students participated for 1.5 semesters. In comparing the use of the study toll, and without the tool, the alterations were found between traditional classroom learning style and online study. Also, the study’s aim was to attest the online study tool’s efficiency. However, these results were not obvious when the achievement factor was controlled by the limitation of time. The primary purpose of this study is to evaluate these two groups of students with extended experiment time for a noticeable result by used questionnaires course examination, and inventory of ILP learning process. The observed, shows that students with online study tools scored higher on course examinations after measures by the mentioned methodology.

  20. Software-based evaluation of human attractiveness: a pilot study.

    Science.gov (United States)

    Patzelt, Sebastian B M; Schaible, Leonie K; Stampf, Susanne; Kohal, Ralf J

    2014-11-01

    The difficulty of evaluating esthetics in an unbiased way may be overcome by using automated software applications. The purpose of this study was to assess the use of a smartphone application as an objective tool for evaluating attractiveness and to evaluate its potential in dentistry. Ten white participants (mean age ±SD, 42.1 ±22.6 years) were randomly chosen, and frontal facial pictures of each participant were made. The smartphone application PhotoGenic was used to evaluate the attractiveness of the participants. For comparison, 100 randomly (age>16 years, social environment of the research team) selected raters were asked to evaluate the same participants. The influence of participants' facial expression, age, and sex as well as the raters' age, sex, and occupation was investigated. Statistical analyses (linear mixed models with random intercepts; least square means, 95% confidence interval; Pattractiveness score of 6.4 ±1.2 and the rater group of 4.9 ±1.8 (Pattractiveness scores. The participants' sex, facial expression, and age seemed to not be of high relevance; however, the raters' sex and occupation had an impact on the evaluation. PhotoGenic rated the participants' attractiveness with higher scores (more attractive) than did the human raters. Currently, PhotoGenic is not used as an objective evaluation tool for treatment outcomes for dental treatments because the visibility of the teeth (smiling facial expression) has no influence on the evaluation. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  1. Student Evaluation of Teaching: A Case Study from School of ...

    African Journals Online (AJOL)

    USER

    from School of Medicine (UNZA). Sekelani S. Banda. Department of Medical Education Development. School of Medicine, University of Zambia. Lusaka, Zambia. ABSTRACT. Purpose: This paper presents a case study of an academic department's experience with evaluation. The purpose is to review the impact of student.

  2. A preliminary study on semen collection, evaluation and ...

    African Journals Online (AJOL)

    This preliminary study was carried out with 6 local turkey (Meleagris gallopavo) by collecting semen from 2 toms and insemination into 4 hen. The semen collection was achieved by the method of abdominal massage. It was evaluated based on volume, mass motility, live-dead-ratio and sperm concentration, which were; ...

  3. Phytochemical Study and Evaluation of the Antimicrobial and ...

    African Journals Online (AJOL)

    This work aims for the phytochemical study and evaluation of the antioxidant activity of phenolic compounds and essential oils of medicinal plant Pistacia lentiscus L. quantitatively and qualitatively. Through the results obtained, it appears that the leaves and fruits are rich in substances with a high antioxidant power.

  4. Peaceful Uses Bona Fides: Criteria for Evaluation and Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Ajemian, Chris K.; Hazel, Mike; Kessler, Carol E.; Mathews, Carrie E.; Morris, Fred A.; Seward, Amy M.; Peterson, Danielle J.; Smith, Brian W.

    2007-06-06

    This study applies a set of indicators to assess the peaceful nature of a state’s nuclear program. Evaluation of a country’s nuclear program relative to these indicators can help the international community to take appropriate actions to ensure that the growth of the global nuclear energy industry proceeds peacefully and to minimize nuclear proliferation risks.

  5. Sponsorship Evaluation Scale (SES): a validity and reliability study ...

    African Journals Online (AJOL)

    The evaluation of consumer response to sport sponsorship is limited in the academic literature. This research was aimed to conduct a dimensionality, validity and reliability study of the Speed and Thompson Sponsorship Questionnaire in Turkey (2000). Eight hundred and fifty-two (852) university students participated in the ...

  6. Building Assessment Survey and Evaluation Study Summarized Data - HVAC Characteristics

    Science.gov (United States)

    In the Building Assessment Survey and Evaluation (BASE) Study Information on the characteristics of the heating, ventilation, and air conditioning (HVAC) system(s) in the entire BASE building including types of ventilation, equipment configurations, and operation and maintenance issues was acquired by examining the building plans, conducting a building walk-through, and speaking with the building owner, manager, and/or operator.

  7. A retrospective study evaluating the efficacy of identification and ...

    African Journals Online (AJOL)

    Full Title: A retrospective study evaluating the efficacy of identification and management of sepsis at a district-level hospital internal medicine department in the Western Cape Province, South Africa, in comparison with the guidelines stipulated in the 2012 Surviving Sepsis Campaign. Background. Currently there is little ...

  8. Digital Libraries and Repositories in India: An Evaluative Study

    Science.gov (United States)

    Mittal, Rekha; Mahesh, G.

    2008-01-01

    Purpose: The purpose of this research is to identify and evaluate the collections within digital libraries and repositories in India available in the public domain. Design/methodology/approach: The digital libraries and repositories were identified through a study of the literature, as well as internet searching and browsing. The resulting digital…

  9. Evaluating care from a care ethical perspective:: A pilot study.

    Science.gov (United States)

    Kuis, Esther E; Goossensen, Anne

    2017-08-01

    Care ethical theories provide an excellent opening for evaluation of healthcare practices since searching for (moments of) good care from a moral perspective is central to care ethics. However, a fruitful way to translate care ethical insights into measurable criteria and how to measure these criteria has as yet been unexplored: this study describes one of the first attempts. To investigate whether the emotional touchpoint method is suitable for evaluating care from a care ethical perspective. An adapted version of the emotional touchpoint interview method was used. Touchpoints represent the key moments to the experience of receiving care, where the patient recalls being touched emotionally or cognitively. Participants and research context: Interviews were conducted at three different care settings: a hospital, mental healthcare institution and care facility for older people. A total of 31 participants (29 patients and 2 relatives) took part in the study. Ethical considerations: The research was found not to be subject to the (Dutch) Medical Research Involving Human Subjects Act. A three-step care ethical evaluation model was developed and described using two touchpoints as examples. A focus group meeting showed that the method was considered of great value for partaking institutions in comparison with existing methods. Reflection and discussion: Considering existing methods to evaluate quality of care, the touchpoint method belongs to the category of instruments which evaluate the patient experience. The touchpoint method distinguishes itself because no pre-defined categories are used but the values of patients are followed, which is an essential issue from a care ethical perspective. The method portrays the insider perspective of patients and thereby contributes to humanizing care. The touchpoint method is a valuable instrument for evaluating care; it generates evaluation data about the core care ethical principle of responsiveness.

  10. Combining whole-brain voxel-wise analysis with in vivo tractography of diffusion behavior after sports-related concussion in adolescents: a preliminary report.

    Science.gov (United States)

    Borich, Michael; Makan, Nadia; Boyd, Lara; Virji-Babul, Naznin

    2013-07-15

    We have previously shown that sports-related concussion in adolescents is associated with changes in whole-brain properties of white-matter pathways. Here, we assess local changes within these pathways. Twelve adolescents with a clinical diagnosis of subacute concussion and 10 healthy adolescents matched for age, gender, and physical activity completed magnetic resonance imaging scanning. Voxel-wise tract-based spatial statistics and tractography were performed to assess local changes in diffusion-based measures of microstructural properties of white-matter pathways (fractional anisotropy, mean diffusivity, radial diffusivity, and axial diffusivity) between the two groups. Fractional anisotropy values were higher for the concussed group in multiple cluster regions using tract-based spatial statistics, primarily in frontal white-matter regions, including the anterior corona radiata bilaterally. Using these regions of altered diffusion characteristics to seed fiber tractography, significantly reduced axial diffusivity in tracts passing through these areas were detected in the concussed group (p=0.04). A trend toward reduced mean and radial diffusivity in the concussed group was also observed within the same reconstructed tracts. Diffusion behavior within these tracts was significantly correlated with an assessment of concussion status (Sports Concussion Assessment Tool 2). Fractional anisotropy within the reconstructed tracts was not significantly different between the two groups. These results suggest that subacute concussion in adolescents is associated with altered diffusion properties within regional white-matter tissue and along reconstructed fiber pathways. Combining voxel-wise analysis with fiber tractography provides an alternative objective approach to evaluate and identify subtle changes in white-matter fiber integrity after concussion.

  11. Stage-Wise Identification and Analysis of miRNA from Root-Knot Nematode Meloidogyne incognita

    Directory of Open Access Journals (Sweden)

    Parthiban Subramanian

    2016-10-01

    Full Text Available In this study, we investigated global changes in miRNAs of Meloidogyne incognita throughout its life cycle. Small RNA sequencing resulted in approximately 62, 38, 38, 35, and 39 Mb reads in the egg, J2, J3, J4, and female stages, respectively. Overall, we identified 2724 known and 383 novel miRNAs (read count > 10 from all stages, of which 169 known and 13 novel miRNA were common to all the five stages. Among the stage-specific miRNAs, miR-286 was highly expressed in eggs, miR-2401 in J2, miR-8 and miR-187 in J3, miR-6736 in J4, and miR-17 in the female stages. These miRNAs are reported to be involved in embryo and neural development, muscular function, and control of apoptosis. Cluster analysis indicated the presence of 91 miRNA clusters, of which 36 clusters were novel and identified in this study. Comparison of miRNA families with other nematodes showed 17 families to be commonly absent in animal parasitic nematodes and M. incognita. Validation of 43 predicted common and stage-specific miRNA by quantitative PCR (qPCR indicated their expression in the nematode. Stage-wise exploration of M. incognita miRNAs has not been carried out before and this work presents information on common and stage-specific miRNAs of the root-knot nematode.

  12. Report of the Study Group on Assessment and Evaluation

    CERN Document Server

    Crouch, R; Netter, K; Crouch, Richard; Gaizuaskas, Robert; Netter, Klaus

    1996-01-01

    This is an interim report discussing possible guidelines for the assessment and evaluation of projects developing speech and language systems. It was prepared at the request of the European Commission DG XIII by an ad hoc study group, and is now being made available in the form in which it was submitted to the Commission. However, the report is not an official European Commission document, and does not reflect European Commission policy, official or otherwise. After a discussion of terminology, the report focusses on combining user-centred and technology-centred assessment, and on how meaningful comparisons can be made of a variety of systems performing different tasks for different domains. The report outlines the kind of infra-structure that might be required to support comparative assessment and evaluation of heterogenous projects, and also the results of a questionnaire concerning different approaches to evaluation.

  13. Application of Learning Curves for Didactic Model Evaluation: Case Studies

    Directory of Open Access Journals (Sweden)

    Felix Mödritscher

    2013-01-01

    Full Text Available The success of (online courses depends, among other factors, on the underlying didactical models which have always been evaluated with qualitative and quantitative research methods. Several new evaluation techniques have been developed and established in the last years. One of them is ‘learning curves’, which aim at measuring error rates of users when they interact with adaptive educational systems, thereby enabling the underlying models to be evaluated and improved. In this paper, we report how we have applied this new method to two case studies to show that learning curves are useful to evaluate didactical models and their implementation in educational platforms. Results show that the error rates follow a power law distribution with each additional attempt if the didactical model of an instructional unit is valid. Furthermore, the initial error rate, the slope of the curve and the goodness of fit of the curve are valid indicators for the difficulty level of a course and the quality of its didactical model. As a conclusion, the idea of applying learning curves for evaluating didactical model on the basis of usage data is considered to be valuable for supporting teachers and learning content providers in improving their online courses.

  14. The Voxel-Wise Functional Connectome Can Be Efficiently Derived from Co-activations in a Sparse Spatio-Temporal Point-Process.

    Science.gov (United States)

    Tagliazucchi, Enzo; Siniatchkin, Michael; Laufs, Helmut; Chialvo, Dante R

    2016-01-01

    Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions based on large neuroimaging databases. The exploratory unraveling of this "functional connectome" based on functional Magnetic Resonance Imaging (fMRI) can benefit from a better understanding of the contributors to resting state functional connectivity. In this work, we introduce a sparse representation of fMRI data in the form of a discrete point-process encoding high-amplitude events in the blood oxygenation level-dependent (BOLD) signal and we show it contains sufficient information for the estimation of functional connectivity between all pairs of voxels. We validate this method by replicating results obtained with standard whole-brain voxel-wise linear correlation matrices in two datasets. In the first one (n = 71), we study the changes in node strength (a measure of network centrality) during deep sleep. The second is a large database (n = 1147) of subjects in which we look at the age-related reorganization of the voxel-wise network of functional connections. In both cases it is shown that the proposed method compares well with standard techniques, despite requiring only data on the order of 1% of the original BOLD signal time series. Furthermore, we establish that the point-process approach does not reduce (and in one case increases) classification accuracy compared to standard linear correlations. Our results show how large fMRI datasets can be drastically simplified to include only the timings of large-amplitude events, while still allowing the recovery of all pair-wise interactions between voxels. The practical importance of this dimensionality reduction is manifest in the increasing number of collaborative efforts aiming to study large cohorts of healthy subjects as well as patients suffering from brain disease. Our method also suggests that the electrophysiological signals underlying the dynamics of fMRI time series

  15. The voxel-wise functional connectome can be efficiently derived from co-activations in a sparse spatio-temporal point-process

    Directory of Open Access Journals (Sweden)

    Enzo Tagliazucchi

    2016-08-01

    Full Text Available Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions based on large neuroimaging databases. The exploratory unraveling of this functional connectome based on functional Magnetic Resonance Imaging (fMRI can benefit from a better understanding of the contributors to resting state functional connectivity. In this work, we introduce a sparse representation of fMRI data in the form of a discrete point-process encoding high-amplitude events in the blood oxygenation level-dependent (BOLD signal and we show it contains sufficient information for the estimation of functional connectivity between all pairs of voxels. We validate this method by replicating results obtained with standard whole-brain voxel-wise linear correlation matrices in two datasets. In the first one (n=71, we study the changes in node strength (a measure of network centrality during deep sleep. The second is a large database (n=1147 of subjects in which we look at the age-related reorganization of the voxel-wise network of functional connections. In both cases it is shown that the proposed method compares well with standard techniques, despite requiring only data on the order of 1% of the original BOLD signal time series. Furthermore, we establish that the point-process approach does not reduce (and in one case increases classification accuracy compared to standard linear correlations. Our results show how large fMRI datasets can be drastically simplified to include only the timings of large-amplitude events, while still allowing the recovery of all pair-wise interactions between voxels. The practical importance of this dimensionality reduction is manifest in the increasing number of collaborative efforts aiming to study large cohorts of healthy subjects as well as patients suffering from brain disease. Our method also suggests that the electrophysiological signals underlying the dynamics of fMRI time

  16. Evaluation of robotic minimally invasive surgical skills using motion studies.

    Science.gov (United States)

    Jun, Seung-Kook; Sathia Narayanan, Madusudanan; Singhal, Pankaj; Garimella, Sudha; Krovi, Venkat

    2013-09-01

    Robotic Minimally Invasive Surgery, and the engendered computer-integration, offers unique opportunities for quantitative computer-based surgical-performance evaluation. In this work, we examine extension of traditional manipulative skill assessment, having deep roots in performance evaluation in manufacturing industries, for applicability to robotic surgical skill evaluation. This method relies on: defining task-level segmentation of modular sub-tasks/micro-motions called 'Therbligs' that can be combined to perform a given task; and analyzing intra- and inter-user performance variance by studying surgeons' performance over each 'Therbligs'. Any of the performance metrics of macro-motions-from motion-economy, tool motion measurements to handed-symmetry-can now be extended over the micro-motion temporal segments. Evaluation studies were based on video recordings of surgical tasks in two settings: first, we examined performance of two representative manipulation exercises (peg board and pick-and-place) on a da Vinci surgical SKILLS simulator. This affords a relatively-controlled and standardized test-scenarios for surgeons with varied experience-levels. Second, task-sequences from real surgical videos were analyzed with a list of predefined 'Therbligs' in order to investigate its overall usefulness.

  17. Surgery resident selection and evaluation. A critical incident study.

    Science.gov (United States)

    Edwards, J C; Currie, M L; Wade, T P; Kaminski, D L

    1993-03-01

    This article reports a study of the process of selecting and evaluating general surgery residents. In personnel psychology terms, a job analysis of general surgery was conducted using the Critical Incident Technique (CIT). The researchers collected 235 critical incidents through structured interviews with 10 general surgery faculty members and four senior residents. The researchers then directed the surgeons in a two-step process of sorting the incidents into categories and naming the categories. The final essential categories of behavior to define surgical competence were derived through discussion among the surgeons until a consensus was formed. Those categories are knowledge/self-education, clinical performance, diagnostic skills, surgical skills, communication skills, reliability, integrity, compassion, organization skills, motivation, emotional control, and personal appearance. These categories were then used to develop an interview evaluation form for selection purposes and a performance evaluation form to be used throughout residency training. Thus a continuum of evaluation was established. The categories and critical incidents were also used to structure the interview process, which has demonstrated increased interview validity and reliability in many other studies. A handbook for structuring the interviews faculty members conduct with applicants was written, and an interview training session was held with the faculty. The process of implementation of the structured selection interviews is being documented currently through qualitative research.

  18. Data envelopment analysis in service quality evaluation: an empirical study

    Science.gov (United States)

    Najafi, Seyedvahid; Saati, Saber; Tavana, Madjid

    2015-10-01

    Service quality is often conceptualized as the comparison between service expectations and the actual performance perceptions. It enhances customer satisfaction, decreases customer defection, and promotes customer loyalty. Substantial literature has examined the concept of service quality, its dimensions, and measurement methods. We introduce the perceived service quality index (PSQI) as a single measure for evaluating the multiple-item service quality construct based on the SERVQUAL model. A slack-based measure (SBM) of efficiency with constant inputs is used to calculate the PSQI. In addition, a non-linear programming model based on the SBM is proposed to delineate an improvement guideline and improve service quality. An empirical study is conducted to assess the applicability of the method proposed in this study. A large number of studies have used DEA as a benchmarking tool to measure service quality. These models do not propose a coherent performance evaluation construct and consequently fail to deliver improvement guidelines for improving service quality. The DEA models proposed in this study are designed to evaluate and improve service quality within a comprehensive framework and without any dependency on external data.

  19. Assessment of crystalline disorder in cryo-milled samples of indomethacin using atomic pair-wise distribution functions.

    Science.gov (United States)

    Bøtker, Johan P; Karmwar, Pranav; Strachan, Clare J; Cornett, Claus; Tian, Fang; Zujovic, Zoran; Rantanen, Jukka; Rades, Thomas

    2011-09-30

    The aim of this study was to investigate the usefulness of the atomic pair-wise distribution function (PDF) to detect the extension of disorder/amorphousness induced into a crystalline drug using a cryo-milling technique, and to determine the optimal milling times to achieve amorphisation. The PDF analysis was performed on samples of indomethacin obtained by cryogenic ball milling (cryo-milling) for different periods of time. X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC), polarised light microscopy (PLM) and solid state nuclear magnetic resonances (ss-NMR) were also used to analyse the cryo-milled samples. The high similarity between the γ-indomethacin cryogenic ball milled samples and the crude γ-indomethacin indicated that milled samples retained residual order of the γ-form. The PDF analysis encompassed the capability of achieving a correlation with the physical properties determined from DSC, ss-NMR and stability experiments. Multivariate data analysis (MVDA) was used to visualize the differences in the PDF and XRPD data. The MVDA approach revealed that PDF is more efficient in assessing the introduced degree of disorder in γ-indomethacin after cryo-milling than MVDA of the corresponding XRPD diffractograms. The PDF analysis was able to determine the optimal cryo-milling time that facilitated the highest degree of disorder in the samples. Therefore, it is concluded that the PDF technique may be used as a complementary tool to other solid state methods and that further investigations are warranted to elucidate the capabilities of this technique. Copyright © 2010 Elsevier B.V. All rights reserved.

  20. Group-wise similarity registration of point sets using Student's t-mixture model for statistical shape models.

    Science.gov (United States)

    Ravikumar, Nishant; Gooya, Ali; Çimen, Serkan; Frangi, Alejandro F; Taylor, Zeike A

    2018-02-01

    A probabilistic group-wise similarity registration technique based on Student's t-mixture model (TMM) and a multi-resolution extension of the same (mr-TMM) are proposed in this study, to robustly align shapes and establish valid correspondences, for the purpose of training statistical shape models (SSMs). Shape analysis across large cohorts requires automatic generation of the requisite training sets. Automated segmentation and landmarking of medical images often result in shapes with varying proportions of outliers and consequently require a robust method of alignment and correspondence estimation. Both TMM and mrTMM are validated by comparison with state-of-the-art registration algorithms based on Gaussian mixture models (GMMs), using both synthetic and clinical data. Four clinical data sets are used for validation: (a) 2D femoral heads (K= 1000 samples generated from DXA images of healthy subjects); (b) control-hippocampi (K= 50 samples generated from T1-weighted magnetic resonance (MR) images of healthy subjects); (c) MCI-hippocampi (K= 28 samples generated from MR images of patients diagnosed with mild cognitive impairment); and (d) heart shapes comprising left and right ventricular endocardium and epicardium (K= 30 samples generated from short-axis MR images of: 10 healthy subjects, 10 patients diagnosed with pulmonary hypertension and 10 diagnosed with hypertrophic cardiomyopathy). The proposed methods significantly outperformed the state-of-the-art in terms of registration accuracy in the experiments involving synthetic data, with mrTMM offering significant improvement over TMM. With the clinical data, both methods performed comparably to the state-of-the-art for the hippocampi and heart data sets, which contained few outliers. They outperformed the state-of-the-art for the femur data set, containing large proportions of outliers, in terms of alignment accuracy, and the quality of SSMs trained, quantified in terms of generalization, compactness and

  1. Penny wise, pound foolish: an assessment of Canadian Hemophilia/inherited bleeding disorder comprehensive care program services and resources.

    Science.gov (United States)

    Page, D; Crymble, S; Lawday, K; Long, M; Stoffman, J; Waterhouse, L; Wilton, P

    2016-07-01

    A network of 25 haemophilia/inherited bleeding disorder comprehensive care centres was established in Canada in the 1970s and 1980s. In 2007, standards of care, focused on the structural and resource requirements necessary to effectively provide optimal care, were adopted. Assess how human and physical resources affect centres' capacity to attain standards of care. The Canadian Hemophilia Society (CHS), with the support of the Association of Hemophilia Clinic Directors of Canada (AHCDC), undertook the assessment. Health care providers were interviewed in person by lay CHS volunteers and staff. A comprehensive patient satisfaction survey was mailed to a representative cross-section of patients/caregivers. The CHS observed that, despite competent and dedicated staff, many of the programmes are experiencing serious resource deficiencies. Twenty-three of the 25 programmes lack resources in one or more of the following disciplines: haematology, nursing, physiotherapy, social work and clerical/data entry. In nine of the 25 programmes, no resources are allocated to certain core disciplines, notably physiotherapy and social work. Key standards of care, including regular health assessments and close monitoring of home infusion with factor concentrates, are not always respected. Nevertheless, a high level of satisfaction was observed among patients and their caregivers. The study also discovered that clotting factor concentrates constitute 90-95% of the total cost of care while all other aspects of care delivery represent only 5-10%. Under-funding of programmes and suboptimal monitoring of valuable clotting factor concentrate utilization and reporting are both 'penny-wise' and 'pound-foolish'. A formal accreditation process is needed. © 2016 John Wiley & Sons Ltd.

  2. High performance APCS conceptual design and evaluation scoping study

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, N.; Liekhus, K.; Chambers, A.; Anderson, G.

    1998-02-01

    This Air Pollution Control System (APCS) Conceptual Design and Evaluation study was conducted to evaluate a high-performance (APC) system for minimizing air emissions from mixed waste thermal treatment systems. Seven variations of high-performance APCS designs were conceptualized using several design objectives. One of the system designs was selected for detailed process simulation using ASPEN PLUS to determine material and energy balances and evaluate performance. Installed system capital costs were also estimated. Sensitivity studies were conducted to evaluate the incremental cost and benefit of added carbon adsorber beds for mercury control, specific catalytic reduction for NO{sub x} control, and offgas retention tanks for holding the offgas until sample analysis is conducted to verify that the offgas meets emission limits. Results show that the high-performance dry-wet APCS can easily meet all expected emission limits except for possibly mercury. The capability to achieve high levels of mercury control (potentially necessary for thermally treating some DOE mixed streams) could not be validated using current performance data for mercury control technologies. The engineering approach and ASPEN PLUS modeling tool developed and used in this study identified APC equipment and system performance, size, cost, and other issues that are not yet resolved. These issues need to be addressed in feasibility studies and conceptual designs for new facilities or for determining how to modify existing facilities to meet expected emission limits. The ASPEN PLUS process simulation with current and refined input assumptions and calculations can be used to provide system performance information for decision-making, identifying best options, estimating costs, reducing the potential for emission violations, providing information needed for waste flow analysis, incorporating new APCS technologies in existing designs, or performing facility design and permitting activities.

  3. Synthesis, reactivity studies and biological evaluation of novel bisphosphonates

    OpenAIRE

    2014-01-01

    Ph.D. (Chemistry) This thesis was devoted to the synthesis of new bisphosphonates molecules, the study of their reactivity and the evaluation of their biological activities. The synthesis of epoxyalkylgembisphosphonates was carried out in three steps. The first step was the synthesis of arynyl and alkynylphosphonates by metallation of alkyl and aryl acetylenes followed by condensation with diethylchlorophosphate at low temperature. The second step was the synthesis of vinylgembisphosphonat...

  4. Evaluation of multi-echo ICA denoising for task based fMRI studies: Block designs, rapid event-related designs, and cardiac-gated fMRI.

    Science.gov (United States)

    Gonzalez-Castillo, Javier; Panwar, Puja; Buchanan, Laura C; Caballero-Gaudes, Cesar; Handwerker, Daniel A; Jangraw, David C; Zachariou, Valentinos; Inati, Souheil; Roopchansingh, Vinai; Derbyshire, John A; Bandettini, Peter A

    2016-11-01

    Multi-echo fMRI, particularly the multi-echo independent component analysis (ME-ICA) algorithm, has previously proven useful for increasing the sensitivity and reducing false positives for functional MRI (fMRI) based resting state connectivity studies. Less is known about its efficacy for task-based fMRI, especially at the single subject level. This work, which focuses exclusively on individual subject results, compares ME-ICA to single-echo fMRI and a voxel-wise T2(⁎) weighted combination of multi-echo data for task-based fMRI under the following scenarios: cardiac-gated block designs, constant repetition time (TR) block designs, and constant TR rapid event-related designs. Performance is evaluated primarily in terms of sensitivity (i.e., activation extent, activation magnitude, percent detected trials and effect size estimates) using five different tasks expected to evoke neuronal activity in a distributed set of regions. The ME-ICA algorithm significantly outperformed all other evaluated processing alternatives in all scenarios. Largest improvements were observed for the cardiac-gated dataset, where ME-ICA was able to reliably detect and remove non-neural T1 signal fluctuations caused by non-constant repetition times. Although ME-ICA also outperformed the other options in terms of percent detection of individual trials for rapid event-related experiments, only 46% of all events were detected after ME-ICA; suggesting additional improvements in sensitivity are required to reliably detect individual short event occurrences. We conclude the manuscript with a detailed evaluation of ME-ICA outcomes and a discussion of how the ME-ICA algorithm could be further improved. Overall, our results suggest that ME-ICA constitutes a versatile, powerful approach for advanced denoising of task-based fMRI, not just resting-state data. Published by Elsevier Inc.

  5. Wisdom of the crowd: bright ideas and innovations from the teaching value and choosing wisely challenge.

    Science.gov (United States)

    Shah, Neel; Levy, Andrew E; Moriates, Christopher; Arora, Vineet M

    2015-05-01

    Medical education has been cited as both part of the problems facing, and part of the solution to reforming, the increasingly challenging U.S. health care system which is fraught with concerns regarding the quality and affordability of care. To teach value in ways that are impactful, sustainable, and scalable, the best and brightest ideas need to be shared such that educators can build on successful existing innovations. To identify the most promising innovations and bright ideas for teaching value to clinical trainees, the authors hosted the "Teaching Value and Choosing Wisely Challenge." The challenge used crowdsourcing methods to solicit scalable, pedagogical approaches from across North America, and then draw generalizable lessons. The authors received 74 submissions (28 innovations; 46 bright ideas) from 14 students, 20 residents/fellows, 38 faculty members (ranging from instructors to full professors), and 2 nonclinical administrators. Submissions represented 14 clinical disciplines including internal medicine, emergency medicine, surgery, pediatrics, obstetrics-gynecology, laboratory medicine, and pharmacy. Thirty-nine abstracts focused on graduate medical education, 15 addressed undergraduate medical education, and 20 applied to both. The authors have solicited, shared, and described solutions for teaching high-value care to medical trainees. Challenge participants demonstrated commitment to improving value and ingenuity in addressing professional barriers to change. Further success requires strong local faculty champions and willing trainee participants. Additionally, the use of data to demonstrate the collective positive impact of these ideas and programs will be critical for sustaining pedagogical changes in the health professions.

  6. Remarks on Politics and Language(s Concerning Alphonso X «the Wise»

    Directory of Open Access Journals (Sweden)

    Carlos Folgar

    2016-12-01

    Full Text Available According to some philologists, certain linguistic behaviours adopted by the king Alphonso X the Wise in his use of the Castilian language were due to his Castilian nationalism. Nevertheless, our view is quite different. On the one hand, we accept the existence of the Castilian monarch’s political nationalism, which is manifest in his various expansionist ambitions (North Africa, Portuguese Algarve, Navarre, Germanic Empire…. But, on the other hand, we find no evidence of political nationalist ideology in the linguistic domain. In order to deny the king’s linguistic nationalism, the best way, in our opinion, is to remember his positive assessment of the Galician Portuguese language, which he made use of for writing his poetic work, particularly the Cantigas de Santa Maria. In this respect, this text becomes very important and very meaningful, not only in literary history but also from the linguistic point of view, because the king expresses in it —in Galician-Portuguese, not in Castilian— his religious zeal and his devotion to the Blessed Virgin.

  7. Pixel-wise orthogonal decomposition for color illumination invariant and shadow-free image.

    Science.gov (United States)

    Qu, Liangqiong; Tian, Jiandong; Han, Zhi; Tang, Yandong

    2015-02-09

    In this paper, we propose a novel, effective and fast method to obtain a color illumination invariant and shadow-free image from a single outdoor image. Different from state-of-the-art methods for shadow-free image that either need shadow detection or statistical learning, we set up a linear equation set for each pixel value vector based on physically-based shadow invariants, deduce a pixel-wise orthogonal decomposition for its solutions, and then get an illumination invariant vector for each pixel value vector on an image. The illumination invariant vector is the unique particular solution of the linear equation set, which is orthogonal to its free solutions. With this illumination invariant vector and Lab color space, we propose an algorithm to generate a shadow-free image which well preserves the texture and color information of the original image. A series of experiments on a diverse set of outdoor images and the comparisons with the state-of-the-art methods validate our method.

  8. Thermophysical properties of near-Earth asteroid (341843) 2008 EV5 from WISE data

    Science.gov (United States)

    Alí-Lagoa, V.; Lionni, L.; Delbo, M.; Gundlach, B.; Blum, J.; Licandro, J.

    2014-01-01

    Aims: We derive the thermal inertia of 2008 EV5, the baseline target for the Marco Polo-R mission proposal, and infer information about the size of the particles on its surface. Methods: Values of thermal inertia were obtained by fitting an asteroid thermophysical model to NASA's Wide-field Infrared Survey Explorer (WISE) infrared data. Grain size was derived from the constrained thermal inertia and a model of heat conductivity that accounts for different values of the packing fraction (a measure of the degree of compaction of the regolith particles). Results: We obtain an effective diameter D = 370 ± 6 m, geometric visible albedo pV = 0.13 ± 0.05 (assuming H = 20.0 ± 0.4), and thermal inertia Γ = 450 ± 60 J m-2 s-1/2 K-1 at the 1σ level of significance for its retrograde spin-pole solution. The regolith particles radius is r = 6.6+1.3-1.3 mm for low degrees of compaction and r = 12.5+2.7-2.6 mm for the highest packing densities. Table of observed fluxes is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/561/A45

  9. Enhanced JPEG2000 Quality Scalability through Block-Wise Layer Truncation

    Directory of Open Access Journals (Sweden)

    Auli-Llinas Francesc

    2010-01-01

    Full Text Available Quality scalability is an important feature of image and video coding systems. In JPEG2000, quality scalability is achieved through the use of quality layers that are formed in the encoder through rate-distortion optimization techniques. Quality layers provide optimal rate-distortion representations of the image when the codestream is transmitted and/or decoded at layer boundaries. Nonetheless, applications such as interactive image transmission, video streaming, or transcoding demand layer fragmentation. The common approach to truncate layers is to keep the initial prefix of the to-be-truncated layer, which may greatly penalize the quality of decoded images, especially when the layer allocation is inadequate. So far, only one method has been proposed in the literature providing enhanced quality scalability for compressed JPEG2000 imagery. However, that method provides quality scalability at the expense of high computational costs, which prevents its application to the aforementioned applications. This paper introduces a Block-Wise Layer Truncation (BWLT that, requiring negligible computational costs, enhances the quality scalability of compressed JPEG2000 images. The main insight behind BWLT is to dismantle and reassemble the to-be-fragmented layer by selecting the most relevant codestream segments of codeblocks within that layer. The selection process is conceived from a rate-distortion model that finely estimates rate-distortion contributions of codeblocks. Experimental results suggest that BWLT achieves near-optimal performance even when the codestream contains a single quality layer.

  10. First Extended Catalogue of Galactic bubble infrared fluxes from WISE and Herschel surveys

    Science.gov (United States)

    Bufano, F.; Leto, P.; Carey, D.; Umana, G.; Buemi, C.; Ingallinera, A.; Bulpitt, A.; Cavallaro, F.; Riggi, S.; Trigilio, C.; Molinari, S.

    2018-01-01

    In this paper, we present the first extended catalogue of far-infrared fluxes of Galactic bubbles. Fluxes were estimated for 1814 bubbles, defined here as the 'golden sample', and were selected from the Milky Way Project First Data Release (Simpson et al.) The golden sample was comprised of bubbles identified within the Wide-field Infrared Survey Explorer (WISE) dataset (using 12- and 22-μm images) and Herschel data (using 70-, 160-, 250-, 350- and 500-μm wavelength images). Flux estimation was achieved initially via classical aperture photometry and then by an alternative image analysis algorithm that used active contours. The accuracy of the two methods was tested by comparing the estimated fluxes for a sample of bubbles, made up of 126 H II regions and 43 planetary nebulae, which were identified by Anderson et al. The results of this paper demonstrate that a good agreement between the two was found. This is by far the largest and most homogeneous catalogue of infrared fluxes measured for Galactic bubbles and it is a step towards the fully automated analysis of astronomical datasets.

  11. José Miguel Jiménez receives Order of Alfonso X the Wise

    CERN Multimedia

    CERN Bulletin

    2016-01-01

    On 12 July 2016, José Miguel Jiménez, Head of CERN Technology Department, has been awarded a spanish civil decoration — an encomienda — of the Order of Alfonso X the Wise (see here), for his outstanding experience in the field of research and scientific management in particle physics.   The ceremony took place at the National Library of Spain, in Madrid, on 12 July. From left: Marcial Marín Hellín, Secretary of State for Education, Professional training and Universities; José María Lassalle Ruiz, Secretary of State for Culture; Íñigo Méndez de Vigo y Montojo, Ministry of Education, Culture and Sport; José Miguel Jiménez, Head of CERN Technology Department; Carmen Vela Olmo, Secretary of State for Investigation, Development and Innovation. (Photo: ©Javier Martínez de la Torre, M...

  12. Payer Type and Low-Value Care: Comparing Choosing Wisely Services across Commercial and Medicare Populations.

    Science.gov (United States)

    Colla, Carrie H; Morden, Nancy E; Sequist, Thomas D; Mainor, Alexander J; Li, Zhonghe; Rosenthal, Meredith B

    2017-02-19

    To compare low-value health service use among commercially insured and Medicare populations and explore the influence of payer type on the provision of low-value care. 2009-2011 national Medicare and commercial insurance administrative data. We created claims-based algorithms to measure seven Choosing Wisely-identified low-value services and examined the correlation between commercial and Medicare overuse overall and at the regional level. Regression models explored associations between overuse and regional characteristics. We created measures of early imaging for back pain, vitamin D screening, cervical cancer screening over age 65, prescription opioid use for migraines, cardiac testing in asymptomatic patients, short-interval repeat bone densitometry (DXA), preoperative cardiac testing for low-risk surgery, and a composite of these. Prevalence of four services was similar across the insurance-defined groups. Regional correlation between Medicare and commercial overuse was high (correlation coefficient = 0.540-0.905) for all measures. In both groups, similar region-level factors were associated with low-value care provision, especially total Medicare spending and ratio of specialists to primary care physicians. Low-value care appears driven by factors unrelated to payer type or anticipated reimbursement. These findings suggest the influence of local practice patterns on care without meaningful discrimination by payer type. © Health Research and Educational Trust.

  13. "Choosing wisely" to reduce low-value care: a conceptual and ethical analysis.

    Science.gov (United States)

    Blumenthal-Barby, J S

    2013-10-01

    The American Board of Internal Medicine (ABIM) Foundation has recently initiated a campaign called "Choosing Wisely," which is aimed at reducing "low-value" care services. Lists of low-value care services are being developed and the ABIM Foundation is urging the American Medical Association and other organizations to get behind the lists, disseminate them, and implement them. Yet, there are many ethical questions that remain about the development, dissemination, and implementation of these low-value care lists. In this paper I argue for conceptual clarity with respect to the label "low-value care." Thus far it has not been precisely defined, and I argue that there are actually 10 distinct categories of low-value care. I discuss the ethical challenges and considerations associated with each category. I also provide arguments that can be used to justify the reduction of some of these categories of low-value care. These arguments rely on Rawlsian and Hegelian notions of justice, as well as on concepts about the fiduciary obligations of physicians. Finally, I outline the various mechanisms that could be utilized for the reduction of low-value care (i.e., incentives, punishments, nonrational influences such as appeals to social norms, emotions, or ego, and creation of conditions that make avoidance easy such as defaults and reminders). I provide normative guidelines for the use of each.

  14. DIALIGN P: Fast pair-wise and multiple sequence alignment using parallel processors

    Directory of Open Access Journals (Sweden)

    Kaufmann Michael

    2004-09-01

    Full Text Available Abstract Background Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. Results Herein, a parallel version of the multi-alignment program DIALIGN is introduced. We propose two ways of dividing the program into independent sub-routines that can be run on different processors: (a pair-wise sequence alignments that are used as a first step to multiple alignment account for most of the CPU time in DIALIGN. Since alignments of different sequence pairs are completely independent of each other, they can be distributed to multiple processors without any effect on the resulting output alignments. (b For alignments of large genomic sequences, we use a heuristics by splitting up sequences into sub-sequences based on a previously introduced anchored alignment procedure. For our test sequences, this combined approach reduces the program running time of DIALIGN by up to 97%. Conclusions By distributing sub-routines to multiple processors, the running time of DIALIGN can be crucially improved. With these improvements, it is possible to apply the program in large-scale genomics and proteomics projects that were previously beyond its scope.

  15. Grating Oriented Line-Wise Filtration (GOLF) for Dual-Energy X-ray CT

    Science.gov (United States)

    Xi, Yan; Cong, Wenxiang; Harrison, Daniel; Wang, Ge

    2017-12-01

    In medical X-ray Computed Tomography (CT), the use of two distinct X-ray source spectra (energies) allows dose-reduction and material discrimination relative to that achieved with only one source spectrum. Existing dual-energy CT methods include source kVp-switching, double-layer detection, dual-source gantry, and two-pass scanning. Each method suffers either from strong spectral correlation or patient-motion artifacts. To simultaneously address these problems, we propose to improve CT data acquisition with the Grating Oriented Line-wise Filtration (GOLF) method, a novel X-ray filter that is placed between the source and patient. GOLF uses a combination of absorption and filtering gratings that are moved relative to each other and in synchronization with the X-ray tube kVp-switching process and/or the detector view-sampling process. Simulation results show that GOLF can improve the spectral performance of kVp-switching to match that of dual-source CT while avoiding patient motion artifacts and dual imaging chains. Although significant flux is absorbed by this pre-patient filter, the proposed GOLF method is a novel path for cost-effectively extracting dual-energy or multi-energy data and reducing radiation dose with or without kVp switching.

  16. Optimising query execution time in LHCb Bookkeeping System using partition pruning and Partition-Wise joins

    Science.gov (United States)

    Mathe, Zoltan; Charpentier, Philippe

    2014-06-01

    The LHCb experiment produces a huge amount of data which has associated metadata such as run number, data taking condition (detector status when the data was taken), simulation condition, etc. The data are stored in files, replicated on the Computing Grid around the world. The LHCb Bookkeeping System provides methods for retrieving datasets based on their metadata. The metadata is stored in a hybrid database model, which is a mixture of Relational and Hierarchical database models and is based on the Oracle Relational Database Management System (RDBMS). The database access has to be reliable and fast. In order to achieve a high timing performance, the tables are partitioned and the queries are executed in parallel. When we store large amounts of data the partition pruning is essential for database performance, because it reduces the amount of data retrieved from the disk and optimises the resource utilisation. This research presented here is focusing on the extended composite partitioning strategy such as range-hash partition, partition pruning and usage of the Partition-Wise joins. The system has to serve thousands of queries per minute, the performance and capability of the system is measured when the above performance optimization techniques are used.

  17. The phenotypic equilibrium of cancer cells: From average-level stability to path-wise convergence.

    Science.gov (United States)

    Niu, Yuanling; Wang, Yue; Zhou, Da

    2015-12-07

    The phenotypic equilibrium, i.e. heterogeneous population of cancer cells tending to a fixed equilibrium of phenotypic proportions, has received much attention in cancer biology very recently. In the previous literature, some theoretical models were used to predict the experimental phenomena of the phenotypic equilibrium, which were often explained by different concepts of stabilities of the models. Here we present a stochastic multi-phenotype branching model by integrating conventional cellular hierarchy with phenotypic plasticity mechanisms of cancer cells. Based on our model, it is shown that: (i) our model can serve as a framework to unify the previous models for the phenotypic equilibrium, and then harmonizes the different kinds of average-level stabilities proposed in these models; and (ii) path-wise convergence of our model provides a deeper understanding to the phenotypic equilibrium from stochastic point of view. That is, the emergence of the phenotypic equilibrium is rooted in the stochastic nature of (almost) every sample path, the average-level stability just follows from it by averaging stochastic samples. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. GPU-Based Block-Wise Nonlocal Means Denoising for 3D Ultrasound Images

    Directory of Open Access Journals (Sweden)

    Liu Li

    2013-01-01

    Full Text Available Speckle suppression plays an important role in improving ultrasound (US image quality. While lots of algorithms have been proposed for 2D US image denoising with remarkable filtering quality, there is relatively less work done on 3D ultrasound speckle suppression, where the whole volume data rather than just one frame needs to be considered. Then, the most crucial problem with 3D US denoising is that the computational complexity increases tremendously. The nonlocal means (NLM provides an effective method for speckle suppression in US images. In this paper, a programmable graphic-processor-unit- (GPU- based fast NLM filter is proposed for 3D ultrasound speckle reduction. A Gamma distribution noise model, which is able to reliably capture image statistics for Log-compressed ultrasound images, was used for the 3D block-wise NLM filter on basis of Bayesian framework. The most significant aspect of our method was the adopting of powerful data-parallel computing capability of GPU to improve the overall efficiency. Experimental results demonstrate that the proposed method can enormously accelerate the algorithm.

  19. WISE Y dwarfs as probes of the brown dwarf-exoplanet connection

    Energy Technology Data Exchange (ETDEWEB)

    Beichman, C.; Gelino, Christopher R.; Kirkpatrick, J. Davy [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States); Cushing, Michael C. [Department of Physics and Astronomy, The University of Toledo, 2801 West Bancroft Street, Toledo, OH 43606 (United States); Dodson-Robinson, Sally [Department of Astronomy, University of Delaware, Newark, DE 19716 (United States); Marley, Mark S. [NASA Ames Research Center, Mountain View, CA 94035 (United States); Morley, Caroline V. [Department of Astronomy, University of California at Santa Cruz, Santa Cruz, CA 95064 (United States); Wright, E. L., E-mail: chas@ipac.caltech.edu [Department of Astronomy, University of California Los Angeles, P.O. Box 951547, Los Angeles, CA 90095 (United States)

    2014-03-10

    We have determined astrometric positions for 15 WISE-discovered late-type brown dwarfs (six T8-9 and nine Y dwarfs) using the Keck-II telescope, the Spitzer Space Telescope, and the Hubble Space Telescope. Combining data from 8 to 20 epochs we derive parallactic and proper motions for these objects, which puts the majority within 15 pc. For ages greater than a few Gyr, as suggested from kinematic considerations, we find masses of 10-30 M {sub Jup} based on standard models for the evolution of low-mass objects with a range of mass estimates for individual objects, depending on the model in question. Three of the coolest objects have effective temperatures ∼350 K and inferred masses of 10-15 M {sub Jup}. Our parallactic distances confirm earlier photometric estimates and direct measurements and suggest that the number of objects with masses below about 15 M {sub Jup} must be flat or declining, relative to higher mass objects. The masses of the coldest Y dwarfs may be similar to those inferred for recently imaged planet-mass companions to nearby young stars. Objects in this mass range, which appear to be rare in both the interstellar and protoplanetary environments, may both have formed via gravitational fragmentation—the brown dwarfs in interstellar clouds and companion objects in a protoplanetary disk. In both cases, however, the fact that objects in this mass range are relatively infrequent suggests that this mechanism must be inefficient in both environments.

  20. Software-based evaluation of human age: a pilot study.

    Science.gov (United States)

    Patzelt, Sebastian B M; Schaible, Leonie K; Stampf, Susanne; Kohal, Ralf J

    2015-01-01

    This pilot study was to assess a smartphone application regarding its use as an objective evaluation tool for subject age in comparison to human raters and to identify potential factors influencing the estimation of age. Ten Caucasian participants (six females, four males, mean age 42.1 ± 22.6 years) were randomly chosen, and frontal facial pictures of each participant were taken. The smartphone application PhotoAge (Version 1.5, ©2012, Percipo Inc., San Francisco, CA, USA) was used to evaluate the age of the participants. For comparison, 100 randomly selected raters (60 females, 40 males, mean age 29.3 ± 1.3 years) were asked to evaluate the age of the same participants. The influence of participants' facial expression, age, and sex as well as raters' age, sex, and profession was investigated as well. Statistical analyses (linear mixed models with random intercepts; least square means, confidence interval 95%; p < 0.05) were implemented. PhotoAge resulted in a mean age of 43.1 ± 18.2 years, with a difference from the true mean age of 1.0 ± 8.2 years (p = 0.5996). The evaluation by the raters revealed a mean age of 41.5 ± 19.0 years, with a difference from the true mean age of -0.6 ± 8.5 years (p = 0.6078). There was no statistical significance between the two groups (p = 0.2783). The evaluation of age with the software application PhotoAge seems to be a reliable procedure with comparable results to human raters. This study gives a better understanding about the reliability of a software-based evaluation tool for age and identifies factors (e.g., the visibility of the teeth) potentially affecting the estimation of age. Naturally looking teeth seem to have no influence on the evaluation of a person's age. Thus, the application of this specific application for dental purposes is questionable; however, in forensics, it might be a valuable tool for estimating a person's age. © 2014 Wiley Periodicals, Inc.

  1. METHODS OF EVALUATING LEARNERS STUDYING ENGLISH FOR SPECIAL PURPOSES

    Directory of Open Access Journals (Sweden)

    Abrudan Caciora Simona Veronica

    2014-07-01

    Full Text Available The present paper intends to present the perceptions of 90 students, studying at the University of Oradea, Faculty of Electrical Engineering and Information Technology and Faculty of Civil Engineering and Architecture, about two evaluation methods used at the English course, namely the classical, end-of-semester testing method and the so-called “progressive evaluation”, which is carried out during the course and results from weekly in-class grading. At the end of the two years of studying English as part of their curricula, students were asked to complete an anonymous questionnaire of 11 items, in which they reported either their contentment or discontentment with the two evaluation methods used, and expressed opinions about the efficiency and usefulness of the English course they have attended. A copy of the questionnaire is included as an appendix to this paper. This paper begins with a brief discussion and definition of English for Specific Purposes (ESP, after which it focuses on the description of the evaluation methods applied, on students’ response to these methods and some personal consideration of the advantages and disadvantages of the two evaluation methods. ESP is a very broad domain, referring mainly to teaching English to students or people who need it for specific purposes, i.e. at work, or in their future career. In these faculties ESP is the main instrument for teaching a foreign language. In contrast to general English, ESP starts from the assessment of those functions and purposes for which English is required, as well as of the skills the learner might need most. In order to give students the possibility to compare two evaluation methods, they were evaluated at the end of their first semester, by using a method that is often used at the University of Oradea, namely that of testing learners’ achievement at the end of the semester. Starting with the second semester, we have presented students with the other evaluation

  2. Evaluate VTS benefits: A case study of Zhoushan Port

    Directory of Open Access Journals (Sweden)

    Jun-Min Mou

    2015-12-01

    Full Text Available It has been well acknowledged that Vessel Traffic Services (VTS has played a growing important role to ensure the safety of navigation in the busy ports and waterways. However, the benefits produced by VTS are usually ignored by the public and private sectors. Besides, the previous evaluations generally exist following problems: (1 It is difficult to collect the data for the parameters in the evaluation models and/or the parameters are designed illogically; (2 Those models did not take the following factors into consideration such as reducing the frequency of coastal vessel patrolling and saving human and material resources; (3 It is difficult to clearly discriminate the benefits derived from VTS and non-VTS. In this paper, a framework is presented to calculate the benefits of VTS in China. Four key indicators (safety, traffic efficiency, environmental protection and reducing supervising cost and quantitative methods have been introduced into the framework. When calculating the benefits quantitatively, the traffic condition before the construction (expansion of the VTS has acted as a benchmark. For a case study, the project of the expansion of VTS in Zhoushan Port, East China was evaluated with 10-year data. According to the results, the largest contribution is from the benefit of environmental protection. Via Cost-benefit analysis the benefit cost ratio (B/C of the VTS is up to 5.248, which shows the benefits produced by VTS are considerable. The research could provide references for VTS benefits evaluation and investment optimizing.

  3. [Comparing audiological evaluation and screening: a study on presbycusis].

    Science.gov (United States)

    Samelli, Alessandra Giannella; Negretti, Camila Aparecida; Ueda, Kerli Saori; Moreira, Renata Rodrigues; Schochat, Eliane

    2011-01-01

    Given the high prevalence of presbycusis and the damage it brings about, a screening test can be useful in the identification of hearing loss in primary care. To estimate the prevalence of hearing loss in a representative sample of elderly people living at Butantan using an audiological screening method (questionnaire) and a basic audiological evaluation; to compare the results of the two kinds of evaluations, checking the validity of this tool for hearing loss screening. Cross sectional descriptive study. 200 individuals (above 60 years old, both genders) were randomly selected to undergo audiological screening (questionnaire). Another randomly selected group encompassed 100 individuals who were submitted to a set of audiological tests. Then, we compared the results from the two methods. There were no statistically significant associations between the questionnaire and the degree of hearing loss of the patients. The prevalence of hearing loss in our sample was of 56% in the screening and of 95% when checked by the audiological evaluation. Therefore, screening was not proven valid to assess hearing when compared to audiological evaluation.

  4. Psychometric Evaluation of the Interpersonal Support Evaluation List–Short Form in the ARIC Study Cohort

    Directory of Open Access Journals (Sweden)

    Thomas J. Payne

    2012-09-01

    Full Text Available The impact of social support on health outcomes is well documented. The current study evaluated a short form of the Interpersonal Support Evaluation List (ISEL-SF administered to 14,257 participants in the Atherosclerosis Risk in Communities study. Using confirmatory factor analysis, we attempted to replicate the subscale structure of the full-scale version. Additional analyses were conducted to examine the relationship of ISEL scores to key demographic variables, as well as the relationship with the Lubben Social Support Scale. We replicated the existing full-scale ISEL subscale structure in this short version. In addition, subscale scores were found to differ across gender, race, level of educational attainment, and marital status, although the magnitude of the various effects was modest. Correlations with another established measure of social support provide convergent validity for this abbreviated instrument. Results suggest this brief measure of perceived social support is a psychometrically valid instrument. An evaluation of its clinical utility is warranted.

  5. A SEARCH FOR L/T TRANSITION DWARFS WITH Pan-STARRS1 AND WISE: DISCOVERY OF SEVEN NEARBY OBJECTS INCLUDING TWO CANDIDATE SPECTROSCOPIC VARIABLES

    Energy Technology Data Exchange (ETDEWEB)

    Best, William M. J.; Liu, Michael C.; Magnier, Eugene A.; Aller, Kimberly M.; Burgett, W. S.; Chambers, K. C.; Hodapp, K. W.; Kaiser, N.; Kudritzki, R.-P.; Morgan, J. S.; Tonry, J. L.; Wainscoat, R. J. [Institute for Astronomy, University of Hawaii at Manoa, Honolulu, HI 96822 (United States); Deacon, Niall R. [Max Planck Institute for Astronomy, Koenigstuhl 17, D-69117 Heidelberg (Germany); Dupuy, Trent J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Redstone, Joshua [Facebook, 335 Madison Ave, New York, NY 10017-4677 (United States); Price, P. A., E-mail: wbest@ifa.hawaii.edu [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States)

    2013-11-10

    We present initial results from a wide-field (30,000 deg{sup 2}) search for L/T transition brown dwarfs within 25 pc using the Pan-STARRS1 and Wide-field Infrared Survey Explorer (WISE) surveys. Previous large-area searches have been incomplete for L/T transition dwarfs, because these objects are faint in optical bands and have near-infrared (near-IR) colors that are difficult to distinguish from background stars. To overcome these obstacles, we have cross-matched the Pan-STARRS1 (optical) and WISE (mid-IR) catalogs to produce a unique multi-wavelength database for finding ultracool dwarfs. As part of our initial discoveries, we have identified seven brown dwarfs in the L/T transition within 9-15 pc of the Sun. The L9.5 dwarf PSO J140.2308+45.6487 and the T1.5 dwarf PSO J307.6784+07.8263 (both independently discovered by Mace et al.) show possible spectroscopic variability at the Y and J bands. Two more objects in our sample show evidence of photometric J-band variability, and two others are candidate unresolved binaries based on their spectra. We expect our full search to yield a well-defined, volume-limited sample of L/T transition dwarfs that will include many new targets for study of this complex regime. PSO J307.6784+07.8263 in particular may be an excellent candidate for in-depth study of variability, given its brightness (J = 14.2 mag) and proximity (11 pc)

  6. Quality evaluation of labneh: a study with consumers

    Directory of Open Access Journals (Sweden)

    Mariana Pereira Silveira

    2017-06-01

    Full Text Available The labneh (Greek yoghurt is a type of fermented milk product characterized by the concentration of the solids of the traditional yoghurt. The objectives of this study were to evaluate the acceptance of 3 commercial brands of traditional Greek yogurt marketed in the city of Diamantina/MG; and to identify the attributes that influence the quality of the product. Analysis of the color (L*, a*, b*, texture, acidity, pH and sensory evaluation were performed. It was observed variation among the samples regarding all analyzed parameters but b* value. In relation to the sensory evaluation, throughout the test of means, it was observed that the brands IA and IB were the most accepted. Through the preference map analysis, it could be concluded that the higher percent of lactic acid of the sample IA and the higher firmness of the sample IB were the parameters responsible for the greater acceptance of these brands. It was observed that the texture and acidity are important attributes related to the choice of the product. Therefore, the results of this study may help in future work of development of new formulations.

  7. Studying the Foreign Experience of Evaluating Intellectual Potential of Organizations

    Directory of Open Access Journals (Sweden)

    Pererva Petro G.

    2016-01-01

    Full Text Available The use of intellectual capital (IC is considered in developed countries as a strategic management tool for achievement of the organizations' success in innovative activities. The article is aimed at studying the foreign experience of evaluating intellectual potential of organizations and identifying directions for its advancement and use at the domestic enterprises to improve their innovative activity. An approach to capital structure has been developed, in which the following three parts are allocated: human capital, structural capital, capital of interactions. The proposed general model for research of IC in terms of firm or region allows to evaluate not only the potential, but also several important lines of communication, namely: industrial-technological, market-customer, business environment and society, commercial operations (technology, value creation and the overall development strategy. In the proposed version of studying the IC potential, analytics are combined with management of both strategy and development tactics, based on use of resources of intellectual capital. The scheme of development management through the system of the activities of influence is recommended as well. The end result of the analytical project work provides the development package, which is issued as a supporting document of development strategy. Evaluation of the development level of intellectual capital in the context of individual enterprises and of regional complex in general has been recommended to include in the Regional innovation system (RIS as one of its functional tasks

  8. The ethics of evaluating obesity intervention studies on children.

    Science.gov (United States)

    Wickins-Drazilova, D; Williams, G

    2011-04-01

    The methodology of the IDEFICS (Identification and prevention of dietary- and lifestyle-induced health effects in children and infants) study raises a number of important ethical questions. Many of these are already well recognised in ethical guidelines that uphold principles of individual and parental consent, confidentiality and scientific review. There are, however, wider issues that require ethical reflection. In this paper, we focus on a set of problems surrounding the evaluation of complex social interventions, and argue that comprehensive and objective evaluation is a much more ethically charged aim than it may first appear. In particular, we contend that standard scientific measures-of body size and biomarkers-convey only part of the story. This is partly because, when we intervene in communities, we are also concerned with complex social effects. These effects are made even more complex by contemporary social anxieties about fat and physical appearance, as well as about the safety and security of children. Such anxieties increase the risk of undesirable side effects that are themselves difficult to gauge. In the face of these and other complexities, we argue that the evaluation of interventions should involve a strong ethical dimension. First, it must include-as does the IDEFICS study-consideration of the opinions of the people affected, who are subjected to interventions in ways that necessarily go beyond individual consent. Second, we suggest that interventions might also be assessed by how much they empower people-and especially those persons, such as children, who are otherwise often disempowered.

  9. Wound assessment tools and nurses' needs: an evaluation study.

    Science.gov (United States)

    Greatrex-White, Sheila; Moxey, Helen

    2015-06-01

    The purpose of this study was to ascertain how well different wound assessment tools meet the needs of nurses in carrying out general wound assessment and whether current tools are fit for purpose. The methodology employed was evaluation research. In order to conduct the evaluation, a literature review was undertaken to identify the criteria of an optimal wound assessment tool which would meet nurses' needs. Several freely available wound assessment tools were selected based on predetermined inclusion and exclusion criteria and an audit tool was developed to evaluate the selected tools based on how well they met the criteria of the optimal wound assessment tool. The results provide a measure of how well the selected wound assessment tools meet the criteria of the optimal wound assessment tool. No tool was identified which fulfilled all the criteria, but two (the Applied Wound Management tool and the National Wound Assessment Form) met the most criteria of the optimal tool and were therefore considered to best meet nurses' needs in wound assessment. The study provides a mechanism for the appraisal of wound assessment tools using a set of optimal criteria which could aid practitioners in their search for the best wound assessment tool. © 2013 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd.

  10. Photocatalytic degradation of rosuvastatin: Analytical studies and toxicity evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Machado, Tiele Caprioli, E-mail: tiele@enq.ufrgs.br [Chemical Engineering Department, Federal University of Rio Grande do Sul, Rua Engenheiro Luiz Englert s/n, CEP: 90040-040 Porto Alegre, RS (Brazil); Pizzolato, Tânia Mara [Chemical Institute, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Arenzon, Alexandre [Ecology Center, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Segalin, Jeferson [Biotechnology Center, Federal University of Rio Grande do Sul, Avenida Bento Gonçalves, 9500, CEP: 91501-970 Porto Alegre, RS (Brazil); Lansarin, Marla Azário [Chemical Engineering Department, Federal University of Rio Grande do Sul, Rua Engenheiro Luiz Englert s/n, CEP: 90040-040 Porto Alegre, RS (Brazil)

    2015-01-01

    Photocatalytic degradation of rosuvastatin, which is a drug that has been used to reduce blood cholesterol levels, was studied in this work employing ZnO as catalyst. The experiments were carried out in a temperature-controlled batch reactor that was irradiated with UV light. Preliminary the effects of the photocatalyst loading, the initial pH and the initial rosuvastatin concentration were evaluated. The experimental results showed that rosuvastatin degradation is primarily a photocatalytic process, with pseudo-first order kinetics. The byproducts that were generated during the oxidative process were identified using nano-ultra performance liquid chromatography tandem mass spectrometry (nano-UPLC–MS/MS) and acute toxicity tests using Daphnia magna were done to evaluate the toxicity of the untreated rosuvastatin solution and the reactor effluent. - Highlights: • The photocatalytic degradation of rosuvastatin was studied under UV irradiation. • Commercial catalyst ZnO was used. • Initial rosuvastatin concentration, photocatalyst loading and pH were evaluated. • The byproducts generated during the oxidative process were detected and identified. • Acute toxicity tests using Daphnia magna were carried out.

  11. Evaluating the Impact of Database Heterogeneity on Observational Study Results

    Science.gov (United States)

    Madigan, David; Ryan, Patrick B.; Schuemie, Martijn; Stang, Paul E.; Overhage, J. Marc; Hartzema, Abraham G.; Suchard, Marc A.; DuMouchel, William; Berlin, Jesse A.

    2013-01-01

    Clinical studies that use observational databases to evaluate the effects of medical products have become commonplace. Such studies begin by selecting a particular database, a decision that published papers invariably report but do not discuss. Studies of the same issue in different databases, however, can and do generate different results, sometimes with strikingly different clinical implications. In this paper, we systematically study heterogeneity among databases, holding other study methods constant, by exploring relative risk estimates for 53 drug-outcome pairs and 2 widely used study designs (cohort studies and self-controlled case series) across 10 observational databases. When holding the study design constant, our analysis shows that estimated relative risks range from a statistically significant decreased risk to a statistically significant increased risk in 11 of 53 (21%) of drug-outcome pairs that use a cohort design and 19 of 53 (36%) of drug-outcome pairs that use a self-controlled case series design. This exceeds the proportion of pairs that were consistent across databases in both direction and statistical significance, which was 9 of 53 (17%) for cohort studies and 5 of 53 (9%) for self-controlled case series. Our findings show that clinical studies that use observational databases can be sensitive to the choice of database. More attention is needed to consider how the choice of data source may be affecting results. PMID:23648805

  12. Student nurse mentoring: an evaluative study of the mentor's perspective.

    Science.gov (United States)

    Rylance, Rebecca; Barrett, Julie; Sixsmith, Pam; Ward, Donna

    2017-04-13

    An evaluative study aimed to capture the 'mentor voice' and provide an insight into the mentoring role from the perspective of the nurse mentor. Participants from each of the four fields of nursing practice were asked to comment on the satisfying and frustrating aspects of their mentoring role. The narrative data gleaned from the evaluation were qualitatively analysed and subsequently organised into key themes around the student-mentor relationship and the clinical environment. Given that the landscape of nurse education is set to change, in terms of new standards from the professional bodies and the political drivers, not to mention the changing profile of the student nurse, it is hoped that the findings may help to shape the relationship between the mentor, the student and the higher education institution.

  13. Feasibility Study on Nuclear Propulsion Ship according to Economic Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Gil, Youngmi; Yoo, Seongjin; Oh, June; Byun, Yoonchul; Woo, Ilguk [Daewoo Shipbuilding and Marine Engineering Co., Ltd, Seoul (Korea, Republic of); Kim, Jiho; Choi, Suhn [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    The use of nuclear ships has been extending to the icebreaker, the deep-water exploration ship, and the floating nuclear power plant. Prior to developing the new ship, the relevant regulations need to be considered. In this study, we reviewed the nuclear ship-related regulations. In addition, economic value is one of the most important factors which should be considered in the pre-design phase. To evaluate the economics of the nuclear ship, we calculated Capital Expenditure (abbreviated as CAPEX) and Operation Expenditure (abbreviated as OPEX) for various types of ships. We reviewed the nuclear ship-related regulations and evaluated the economics of the nuclear ship compared to the diesel ship. The calculation result shows that economic feasibility of the nuclear ship depends on the oil price as well as the cost of the nuclear reactor.

  14. The Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE)

    DEFF Research Database (Denmark)

    Rubin, Katrine Hass; Holmberg, Teresa; Rothmann, Mette Juel

    2015-01-01

    The risk-stratified osteoporosis strategy evaluation study (ROSE) is a randomized prospective population-based study investigating the effectiveness of a two-step screening program for osteoporosis in women. This paper reports the study design and baseline characteristics of the study population....... 35,000 women aged 65-80 years were selected at random from the population in the Region of Southern Denmark and-before inclusion-randomized to either a screening group or a control group. As first step, a self-administered questionnaire regarding risk factors for osteoporosis based on FRAX......(®) was issued to both groups. As second step, subjects in the screening group with a 10-year probability of major osteoporotic fractures ≥15 % were offered a DXA scan. Patients diagnosed with osteoporosis from the DXA scan were advised to see their GP and discuss pharmaceutical treatment according to Danish...

  15. Evaluation of the Project Studies in Social Studies Course of Secondary Schools in Turkey

    Science.gov (United States)

    Ibret, B. Unal; Recepoglu, Ergun; Karasu, Emine; Recepoglu, Serpil

    2013-01-01

    The aim of this study is to evaluate project studies in the 6th and 7th grades social studies courses of secondary schools according to opinions of students. This study is a descriptive research in the survey model. The sample is 880 students selected from 6th and 7th grades of 22 secondary schools randomly in central province of Kastamonu. As a…

  16. Comparative Evaluation of Microleakage Between Nano-Ionomer, Giomer and Resin Modified Glass Ionomer Cement in Class V Cavities- CLSM Study

    Science.gov (United States)

    Hari, Archana; Thumu, Jayaprakash; Velagula, Lakshmi Deepa; Bolla, Nagesh; Varri, Sujana; Kasaraneni, Srikanth; Nalli, Siva Venkata Malathi

    2016-01-01

    Introduction Marginal integrity of adhesive restorative materials provides better sealing ability for enamel and dentin and plays an important role in success of restoration in Class V cavities. Restorative material with good marginal adaptation improves the longevity of restorations. Aim Aim of this study was to evaluate microleakage in Class V cavities which were restored with Resin Modified Glass Ionomer Cement (RMGIC), Giomer and Nano-Ionomer. Materials and Methods This in-vitro study was performed on 60 human maxillary and mandibular premolars which were extracted for orthodontic reasons. A standard wedge shaped defect was prepared on the buccal surfaces of teeth with the gingival margin placed near Cemento Enamel Junction (CEJ). Teeth were divided into three groups of 20 each and restored with RMGIC, Giomer and Nano-Ionomer and were subjected to thermocycling. Teeth were then immersed in 0.5% Rhodamine B dye for 48 hours. They were sectioned longitudinally from the middle of cavity into mesial and distal parts. The sections were observed under Confocal Laser Scanning Microscope (CLSM) to evaluate microleakage. Depth of dye penetration was measured in millimeters. Statistical Analysis The data was analysed using the Kruskal Wallis test. Pair wise comparison was done with Mann Whitney U Test. A p-valueIonomer showed less microleakage which was statistically significant when compared to Giomer (p=0.0050). Statistically no significant difference was found between Nano Ionomer and RMGIC (p=0.3550). There was statistically significant difference between RMGIC and Giomer (p=0.0450). Conclusion Nano-Ionomer and RMGIC showed significantly less leakage and better adaptation than Giomer and there was no statistically significant difference between Nano-Ionomer and RMGIC. PMID:27437363

  17. Comparative Evaluation of Microleakage Between Nano-Ionomer, Giomer and Resin Modified Glass Ionomer Cement in Class V Cavities- CLSM Study.

    Science.gov (United States)

    Bollu, Indira Priyadarshini; Hari, Archana; Thumu, Jayaprakash; Velagula, Lakshmi Deepa; Bolla, Nagesh; Varri, Sujana; Kasaraneni, Srikanth; Nalli, Siva Venkata Malathi

    2016-05-01

    Marginal integrity of adhesive restorative materials provides better sealing ability for enamel and dentin and plays an important role in success of restoration in Class V cavities. Restorative material with good marginal adaptation improves the longevity of restorations. Aim of this study was to evaluate microleakage in Class V cavities which were restored with Resin Modified Glass Ionomer Cement (RMGIC), Giomer and Nano-Ionomer. This in-vitro study was performed on 60 human maxillary and mandibular premolars which were extracted for orthodontic reasons. A standard wedge shaped defect was prepared on the buccal surfaces of teeth with the gingival margin placed near Cemento Enamel Junction (CEJ). Teeth were divided into three groups of 20 each and restored with RMGIC, Giomer and Nano-Ionomer and were subjected to thermocycling. Teeth were then immersed in 0.5% Rhodamine B dye for 48 hours. They were sectioned longitudinally from the middle of cavity into mesial and distal parts. The sections were observed under Confocal Laser Scanning Microscope (CLSM) to evaluate microleakage. Depth of dye penetration was measured in millimeters. The data was analysed using the Kruskal Wallis test. Pair wise comparison was done with Mann Whitney U Test. A p-value<0.05 is taken as statistically significant. Nano-Ionomer showed less microleakage which was statistically significant when compared to Giomer (p=0.0050). Statistically no significant difference was found between Nano Ionomer and RMGIC (p=0.3550). There was statistically significant difference between RMGIC and Giomer (p=0.0450). Nano-Ionomer and RMGIC showed significantly less leakage and better adaptation than Giomer and there was no statistically significant difference between Nano-Ionomer and RMGIC.

  18. Developmental neurotoxicity guideline study: issues with methodology, evaluation and regulation.

    Science.gov (United States)

    Tsuji, Ryozo; Crofton, Kevin M

    2012-09-01

    Recently social concerns have been increasing about the effects of environmental factors on children's health, especially on their nervous systems. The U.S. Environmental Protection Agency (EPA) and the Organisation for Economic Co-operation and Development (OECD) have published testing guidelines for developmental neurotoxicity (DNT). Approximately 110 guideline studies have been conducted to date. Importantly, information from these studies has provided data critical for regulatory decisions for a number of chemicals. However, the DNT guidelines do not always satisfy all stakeholders because of some uncertainties in their methodology, evaluation, and regulation. Methodological issues include incomplete harmonization between EPA and OECD guidelines, criticisms of the methodology for learning and memory testing, and unspecified positive control substances. Potential artifacts in morphometric neuropathological measures, criteria for observation measures, uncertainty of postnatal offspring exposure, especially in feeding studies, and extrapolation of data from rats to humans are major evaluation issues. In addition, there is some uncertainty in the use of an additional safety factor for susceptibility of infants and children. Moreover, the DNT guidelines have extensive time and cost requirements, use large numbers of animals, and there is a limited set of laboratories that can conduct the study. This paper reviews some of these issues and summarizes discussions from the symposium 'Developmental neurotoxicity testing: Scientific approaches towards the next generation to protecting the developing nervous system of children' held at the 2011 annual meeting of the Japanese Teratology Society. © 2012 The Authors. Congenital Anomalies © 2012 Japanese Teratology Society.

  19. The 'W.I.S.E. Up!' tool: empowering adopted children to cope with questions and comments about adoption.

    Science.gov (United States)

    Singer, Ellen

    2010-01-01

    Families of adopted children and the children themselves are not strangers to intrusive questions about private information, such as "Is that your real child (or mother)?" and "Why did your mother give you away?" While the questions may be benign, they can be uncomfortable to handle and harmful to a child's self-esteem. To counteract this, The Center for Adoption Support and Education (C.A.S.E.) in Maryland has developed an empowering tool for adoptive children and their families. The "W.I.S.E. Up!" tool is based on the premise that adoptive children are wiser about adoption than peers who are not adopted. The tool uses the acronym W.I.S.E. to teach children four options for responding to uncomfortable questions: W (walk away), I (ignore or change the subject), S (share what you are comfortable sharing), and E (educate about adoption in general). Nurses can assist adoptive families by introducing them to this empowering tool.

  20. Wise Additions Bridge the Gap between Social Psychology and Clinical Practice: Cognitive-Behavioral Therapy as an Exemplar.

    Science.gov (United States)

    Folk, Johanna B; Disabato, David J; Goodman, Fallon R; Carter, Sarah P; DiMauro, Jennifer C; Riskind, John H

    2016-01-01

    Progress in clinical science, theory, and practice requires the integration of advances from multiple fields of psychology, but much integration remains to be done. The current article seeks to address the specific gap that exists between basic social psychological theories and the implementation of related therapeutic techniques. We propose several "wise additions," based upon the principles outlined by Walton (2014), intended to bridge current social psychological research with clinical psychological therapeutic practice using cognitive behavioral therapy as an example. We consider how recent advances in social psychological theories can inform the development and implementation of wise additions in clinical case conceptualization and interventions. We specifically focus on self and identity, self-affirmation, transference, social identity, and embodied cognition, five dominant areas of interest in the field that have clear clinical applications.

  1. B2, B7 or B10: Which palm-based blend mandate wise to be chosen in Malaysia?

    Science.gov (United States)

    Applanaidu, Shri-Dewi; Abidin, Norhaslinda Zainal; Ali, Anizah Md.

    2015-12-01

    The diminishing fossil energy resources, coupled with heightened interest in the abatement of greenhouse gas emissions and concerns about energy security have motivated Malaysia to produce palm-based biodiesel and it has been started to be exported since 2006. In line with this issue, the government in Malaysia launched the palm-based biodiesel blending mandate of five percent (B5) in the federal administration of Putrajaya on 1st June 2011. This was then followed by four states: Malacca on July 11, Negeri Sembilan on August 1, Kuala Lumpur on September 1 and Selangor on October 1 of the same year but it is yet to be implemented nationwide. However what is the wise blend mandate to be chosen? Thus, this paper seeks to examine the possible impact of various blend mandates implementation (B2, B7 and B10) on the palm oil industry market variables (stock and price) since the main aim of biodiesel industry in Malaysia is to reduce domestic palm oil stock to below one million tones and provide a floor price to support Crude Palm Oil (CPO) prices at RM2,000 per tonne. A structural econometric model consisting of nine structural equations and three identities was proposed in this study. The model has been estimated by two stage least squares (2SLS) method using annual data for the period 1976-2013. The study indicates that counterfactual simulation of a decrease from B5 to B2 predicts a decrease (11.2 per cent) in CPO domestic consumption for biodiesel usage, 731.02 per cent reduction in CPO stock and an increase of 27.41 percent in domestic price of CPO. However the increase in the blend mandate from B5 to B7 and B10 suggest that domestic consumption of CPO for biodiesel purpose increase 7.40 and 18.55 percent respectively. The interesting findings in this study suggest that no matter whether Malaysian government increase or decrease the blend mandate the increase in the price of CPO are the same with an increase of is 27.41 percent. Hence, this study suggests that the

  2. B2, B7 or B10: Which palm-based blend mandate wise to be chosen in Malaysia?

    Energy Technology Data Exchange (ETDEWEB)

    Applanaidu, Shri-Dewi, E-mail: dewi@uum.edu.my; Ali, Anizah Md., E-mail: anizah@uum.edu.my [Department of Economics and Agribusiness, School of Economics, Finance & Banking, UUM (Malaysia); Abidin, Norhaslinda Zainal, E-mail: nhaslinda@uum.edu.my [Department of Decision Sciences, School of Quantitative Sciences, UUM (Malaysia)

    2015-12-11

    The diminishing fossil energy resources, coupled with heightened interest in the abatement of greenhouse gas emissions and concerns about energy security have motivated Malaysia to produce palm-based biodiesel and it has been started to be exported since 2006. In line with this issue, the government in Malaysia launched the palm-based biodiesel blending mandate of five percent (B5) in the federal administration of Putrajaya on 1{sup st} June 2011. This was then followed by four states: Malacca on July 11, Negeri Sembilan on August 1, Kuala Lumpur on September 1 and Selangor on October 1 of the same year but it is yet to be implemented nationwide. However what is the wise blend mandate to be chosen? Thus, this paper seeks to examine the possible impact of various blend mandates implementation (B2, B7 and B10) on the palm oil industry market variables (stock and price) since the main aim of biodiesel industry in Malaysia is to reduce domestic palm oil stock to below one million tones and provide a floor price to support Crude Palm Oil (CPO) prices at RM2,000 per tonne. A structural econometric model consisting of nine structural equations and three identities was proposed in this study. The model has been estimated by two stage least squares (2SLS) method using annual data for the period 1976-2013. The study indicates that counterfactual simulation of a decrease from B5 to B2 predicts a decrease (11.2 per cent) in CPO domestic consumption for biodiesel usage, 731.02 per cent reduction in CPO stock and an increase of 27.41 percent in domestic price of CPO. However the increase in the blend mandate from B5 to B7 and B10 suggest that domestic consumption of CPO for biodiesel purpose increase 7.40 and 18.55 percent respectively. The interesting findings in this study suggest that no matter whether Malaysian government increase or decrease the blend mandate the increase in the price of CPO are the same with an increase of is 27.41 percent. Hence, this study suggests that

  3. The scope of costs in alcohol studies: Cost-of-illness studies differ from economic evaluations.

    Science.gov (United States)

    van Gils, Paul F; Hamberg-van Reenen, Heleen H; van den Berg, Matthijs; Tariq, Luqman; de Wit, G Ardine

    2010-07-06

    Alcohol abuse results in problems on various levels in society. In terms of health, alcohol abuse is not only an important risk factor for chronic disease, but it is also related to injuries. Social harms which can be related to drinking include interpersonal problems, work problems, violent and other crimes. The scope of societal costs related to alcohol abuse in principle should be the same for both economic evaluations and cost-of-illness studies. In general, economic evaluations report a small part of all societal costs. To determine the cost- effectiveness of an intervention it is necessary that all costs and benefits are included. The purpose of this study is to describe and quantify the difference in societal costs incorporated in economic evaluations and cost-of-illness studies on alcohol abuse. To investigate the economic costs attributable to alcohol in cost-of-illness studies we used the results of a recent systematic review (June 2009). We performed a PubMed search to identify economic evaluations on alcohol interventions. Only economic evaluations in which two or more interventions were compared from a societal perspective were included. The proportion of health care costs and the proportion of societal costs were estimated in both type of studies. The proportion of healthcare costs in cost-of-illness studies was 17% and the proportion of societal costs 83%. In economic evaluations, the proportion of healthcare costs was 57%, and the proportion of societal costs was 43%. The costs included in economic evaluations performed from a societal perspective do not correspond with those included in cost-of-illness studies. Economic evaluations on alcohol abuse underreport true societal cost of alcohol abuse. When considering implementation of alcohol abuse interventions, policy makers should take into account that economic evaluations from the societal perspective might underestimate the total effects and costs of interventions.

  4. Pixel-Wise-Inter/Intra-Channel Color and Luminance Uniformity Corrections for Multi-Channel Projection Displays

    Science.gov (United States)

    2016-08-11

    Journal Article 3. DATES COVERED (From – To) Jan 2015 – Dec 2015 4. TITLE AND SUBTITLE PIXEL-WISE INTER/INTRA-CHANNEL COLOR & LUMINANCE UNIFORMITY...mask, unique to each projector , which can be inserted into either the projection system or the image generator rendering pipeline to perform the...correction, projector calibration. 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT SAR 18. NUMBER OF PAGES 10 19a. NAME OF

  5. Evaluating a problem based learning course: an action research study.

    Science.gov (United States)

    Walker, J; Bailey, S; Brasell-Brian, R; Gould, S

    2001-03-01

    Problem based learning (PBL) has been widely used in the United States, United Kingdom and Australasia in undergraduate nursing education to develop critical thinking and problem solving skills. PBL has been used since 1996 in a Bachelor of Nursing course at a New Zealand tertiary institution, and several modifications have been made to foster effective learning. The 'pure' PBL process has been adapted to move students gradually from teacher direction to taking responsibility for their learning. This has provided the opportunity for students to develop critical thinking, problem solving, information retrieval and evaluation skills, and group process skills over an 18-week period. Because rigorous evaluation of these changes had not been formally undertaken, the purpose of this study was to evaluate how the current format was developing students' understanding and integration of knowledge. Two cycles of the action research method (Cardno and Piggot-Irvine, 1994) were used, involving 4 lecturers and 17 students. Data was collected both quantitatively and qualitatively over a 16-week period. Findings indicated the importance of: explaining the purpose and process of PBL; communicating in detail the role of both students and lecturers; keeping communication lines open; addressing timetabling issues and valuing this method of learning for nursing practice. Implications for nursing education are addressed.

  6. [Evaluation of ear acupressure on painful shoulder syndrome: case study].

    Science.gov (United States)

    Zanelatto, Ana Paula

    2013-01-01

    The Painful Shoulder Syndrome (PSS) is defined as pain and functional limitation resulting from impairment of static and dynamic structures of the shoulder, such as ligaments, capsule and muscles. It is one of the most common and disabling of the musculoskeletal system in the general population with prevalence estimated between 15-25%. This study aimed to evaluate the results of auricular acupressure when used as therapy in the treatment of chronic pain secondary to SOD, and the analgesic effect and therapeutic satisfactory and the estimated time of treatment. To obtain the objective was to perform a case study was to intervene with auricular acupressure beads and crystals as an indicator of the outcome questionnaire Penn Shoulder Score (PSS - Brazil). Data were analyzed qualitatively and quantitatively. We conclude that auriculotherapy is an important therapeutic technique, because the study showed an improvement in the total score of the PSS - Brazil at 34.3%.

  7. Simulation Studies for the evaluation of health information technologies:

    DEFF Research Database (Denmark)

    Ammenwerth, Elske; Hackl, Werner O; Binzer, Kristine

    2012-01-01

    system on the appropriateness of prescriptions and drugrelated activities, including laboratory test ordering or medication changes. This article presents the results of a controlled simulation study with 50 simulation runs, including ten doctors and fi ve simulation patients, and discusses experiences...... and lessons learnt while conducting the study. Although the new electronic medication management system showed tendencies to improve medication safety when compared with the standard system, this tendency was not significant. Altogether, fi ve distinct situations were identifi ed where the new medication...... management system did help to improve medication safety. This simulation study provided a good compromise between internal validity and external validity. However, several challenges need to be addressed when undertaking simulation evaluations including: preparation of adequate test cases; training...

  8. Evaluation of Empirical Data and Modeling Studies to Support ...

    Science.gov (United States)

    This study is an evaluation of empirical data and select modeling studies of the behavior of petroleum hydrocarbon (PHC) vapors in subsurface soils and how they can affect subsurface-to-indoor air vapor intrusion (VI), henceforth referred to as petroleum vapor intrusion or “PVI” for short. The purpose of this study is to support the development of a soil vapor screening methodology for PHC compounds for the U.S. Environmental Protection Agency’s Office of Underground Storage Tanks (U.S. EPA OUST); consequently, the focus is primarily on characterizing PVI at Subtitle I underground storage tank (UST) sites with petroleum fuel releases. However, PVI data from other types of sites (fuel terminals, petroleum refineries) are also presented and discussed

  9. Evaluation of Xerostomia in Different Psychological Disorders: An Observational Study.

    Science.gov (United States)

    Veerabhadrappa, Suresh Kandagal; Chandrappa, Pramod Redder; Patil, Snehal; Roodmal, Seema Yadav; Kumarswamy, Akshay; Chappi, Mounesh Kumar

    2016-09-01

    Psychiatric diseases like anxiety, depression, schizophrenia and bipolar disorders are increasing at an alarming rate. These diseases can affect the quantity and quality of saliva leading to multiple oral diseases. Although many researchers have evaluated xerostomia in general population, its prevalence is not been assessed in patients suffering from different psychological disorders. To investigate the prevalence of xerostomia and to assess the correlation between xerostomia and dryness of lip and mucosa in different psychological disorders. A cross-sectional observational study was conducted over a period of six months in Department of Psychiatry and Department of Oral Medicine. Patients with anxiety, depression, schizophrenia and bipolar disorder, as diagnosed by an experienced psychiatrist, were given a questionnaire to evaluate the xerostomia. Patients with symptoms of xerostomia were subjected to oral examination by a skilled oral diagnostician to check for dryness of lips and mucosa. One hundred patients from each group of psychiatric diseases were included in the study using a consecutive sampling technique. An equal number of healthy individuals reporting to oral medicine department for routine oral screening were included as control group after initial psychiatric evaluation. In this study statistically significant increase in the xerostomia in psychiatric patients was recorded when compared to the control group (ppsychological alterations. A positive association was established between psychological alterations and xerostomia and dryness of lip and mucosa. Emotional alterations may act as a precipitating factor that could influence the salivary secretion resulting in multiple oral diseases. Psychiatrists can screen for xerostomia and collaborate with dentists for comprehensive management of xerostomia in psychiatric patients.

  10. Histopathological Evaluation of Lymph Node Biopsies: A Hospital Based Study

    Directory of Open Access Journals (Sweden)

    Syeda Tasfia Siddika

    2012-07-01

    Full Text Available Background: Lymphadenopathy is a common manifestation of a large variety of disorders,both benign and malignant. It is essential to define the pattern of disorders presenting primarily as lymph node enlargement in a particular environment. Histopathological examination of the lymph node biopsies is a gold standard test in the distinction between reactive and malignant lymphoid proliferations as well as for detailed subtyping oflymphomas. We designed this study in our population for histopathological evaluation of lymph nodes that might be helpful for clinical management of these lesions. Objective: Histopathological evaluation of lymphadenopathy from excised specimen, in relation to ageand sex of the patients, and distribution of the lymph nodes. Materials and Methods: It was a retrospective cross sectional study conducted in the department of Pathology, Enam Medical College & Hospital, Savar, Dhaka during the period from January 2006 to December 2010. Lymph node biopsies of all patients of both sexes and all age groups were included.Metastatic lymph nodes associated with evidence of primaries elsewhere in the body were excluded from the study. Total 191 lymph node biopsies were selected for histopathological evaluation. Among these 90 (47.12% were from males and 101 (52.88% were from females with male to female ratio being 1:2.1. The age of the patients ranged from 2 to 85 years with a mean age of 35.73 ± 18 years. Results: Cervical lymph nodes were the most common (56% biopsied group. Of the 191 cases 59 cases (30.89% were reactive lymphadenitis, 64 cases (33.5% were tuberculosis, 2 cases (1.05% were non-caseous granuloma, 11 cases (5.76% were Hodgkin lymphoma, 22 cases (11.52% were non-Hodgkin lymphoma, 24 cases (12.57% were metastatic neoplasm and 9 cases (4.7% were other lesions. Conclusion: Tuberculosis was the most common cause of lymphadenopathy, followed by reactive lymphadenitis and the cervical group of lymph nodes was most

  11. A full-sky, high-resolution atlas of galactic 12 μm dust emission with WISE

    Energy Technology Data Exchange (ETDEWEB)

    Meisner, Aaron M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden St., Cambridge, MA 02138 (United States); Finkbeiner, Douglas P., E-mail: ameisner@fas.harvard.edu, E-mail: dfinkbeiner@cfa.harvard.edu [Department of Physics, Harvard University, 17 Oxford Street, Cambridge, MA 02138 (United States)

    2014-01-20

    We describe our custom processing of the entire Wide-field Infrared Survey Explorer (WISE) 12 μm imaging data set, and present a high-resolution, full-sky map of diffuse Galactic dust emission that is free of compact sources and other contaminating artifacts. The principal distinctions between our resulting co-added images and the WISE Atlas stacks are our removal of compact sources, including their associated electronic and optical artifacts, and our preservation of spatial modes larger than 1.°5. We provide access to the resulting full-sky map via a set of 430 12.°5 × 12.°5 mosaics. These stacks have been smoothed to 15'' resolution and are accompanied by corresponding coverage maps, artifact images, and bit-masks for point sources, resolved compact sources, and other defects. When combined appropriately with other mid-infrared and far-infrared data sets, we expect our WISE 12 μm co-adds to form the basis for a full-sky dust extinction map with angular resolution several times better than Schlegel et al.

  12. Wide field of view tabletop light field display based on piece-wise tracking and off-axis pickup

    Science.gov (United States)

    Zhu, Yanhong; Sang, Xinzhu; Yu, Xunbo; Wang, Peng; Xing, Shujun; Chen, Duo; Yan, Binbin; Wang, Kuiru; Yu, Chongxiu

    2017-11-01

    A wide field of view (FOV) tabletop light field display (LFD) based on piece-wise tracking and off-axis pickup is presented to display the floating three-dimensional (3D) scene, which is 360°surrounding viewable. The demonstrated LFD is specially designed with an integral imaging display (IID) with 83 × 83 viewpoints and a full-parallax holographic functional screen (HFS). To improve the FOV, a piece-wise tracking based FOV enhancement method is proposed. The relationship between the viewing zone and the elemental images (EIs) is formulated. A ray-tracing based method using off-axis pickup instead of parallel pickup directly is adopted to render the 3D scene to EIs. Then the piece-wise tracking method of varying the viewing zone by placing the EIs according to the position of viewer is analyzed. The floating 3D scene with a FOV of 70° × 70°is experimentally demonstrated with a good 3D perception.

  13. Synthesis, Computational Studies and Preliminary Pharmacological Evaluation of New Arylpiperazines

    Directory of Open Access Journals (Sweden)

    Sushil Kumar

    2011-01-01

    Full Text Available A series of novel arylpiperazines were synthesized and the target compounds evaluated for atypical antipsychotic activity in apomorphine induced climbing behavior (D2 antagonism, 5-HTP induced head twitches (5-HT2A antagonism and catalepsy studies in albino mice. The physicochemical similarity of the target compounds with respect to standard drugs clozapine, ketanserine and risperidone was assessed by calculating from a set of physiochemical properties using software programs. The test compounds (3a-j demonstrated good similarity values with respect to the standard drugs. Among them, compound 3d has emerged as an important lead compound showing potential atypical antipsychotic like profile.

  14. A Study on the improvement of Paldang dam discharge evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Song, Young Chul; Kim, Chong Hak; Lee, Dae Soo [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center; Lee, Won Hwan; Cho, Won Chul; Heo, Jun Haeng [Yonsei Univ., Seoul (Korea, Republic of)

    1995-12-31

    Besides the original purpose of electric power generation, the Paldang dam plays such important roles as flood control and water supply in the Han river. However, significant drawdown of the downstream water level since 1973 has caused considerable differences between the real discharges and the estimated values currently in use. This study was performed to improve discharge evaluation method and to provide new discharge table appropriate for the changed condition. Through the physical model tests assisted by numerical test, the discharge equations were modified, the discharge table was revised for steady and unsteady flow conditions, but the gate operation rules proved reasonable and remained unchanged. (author). 81 refs., 166 figs.

  15. Synthesis, antimicrobial evaluation and QSAR studies of gallic acid derivatives

    Directory of Open Access Journals (Sweden)

    Anurag Khatkar

    2017-05-01

    Full Text Available A series of gallic acid derivatives (1–33 was synthesized and characterized by physicochemical and spectral means. The synthesized compounds were evaluated in vitro for their antimicrobial activity against different Gram positive and Gram negative bacterial and fungal strains by the tube dilution method. Results of antimicrobial screening indicated that compound 6 was the most active antimicrobial agent (pMICam = 1.92 μM/mL. The results of QSAR studies demonstrated that antibacterial, antifungal and overall antimicrobial activities of synthesized gallic acid derivatives were governed by the electronic parameters, cosmic total energy (Cos E. and nuclear energy (Nu. E..

  16. The "Wireless Sensor Networks for City-Wide Ambient Intelligence (WISE-WAI)" Project.

    Science.gov (United States)

    Casari, Paolo; Castellani, Angelo P; Cenedese, Angelo; Lora, Claudio; Rossi, Michele; Schenato, Luca; Zorzi, Michele

    2009-01-01

    This paper gives a detailed technical overview of some of the activities carried out in the context of the "Wireless Sensor networks for city-Wide Ambient Intelligence (WISE-WAI)" project, funded by the Cassa di Risparmio di Padova e Rovigo Foundation, Italy. The main aim of the project is to demonstrate the feasibility of large-scale wireless sensor network deployments, whereby tiny objects integrating one or more environmental sensors (humidity, temperature, light intensity), a microcontroller and a wireless transceiver are deployed over a large area, which in this case involves the buildings of the Department of Information Engineering at the University of Padova. We will describe how the network is organized to provide full-scale automated functions, and which services and applications it is configured to provide. These applications include long-term environmental monitoring, alarm event detection and propagation, single-sensor interrogation, localization and tracking of objects, assisted navigation, as well as fast data dissemination services to be used, e.g., to rapidly re-program all sensors over-the-air. The organization of such a large testbed requires notable efforts in terms of communication protocols and strategies, whose design must pursue scalability, energy efficiency (while sensors are connected through USB cables for logging and debugging purposes, most of them will be battery-operated), as well as the capability to support applications with diverse requirements. These efforts, the description of a subset of the results obtained so far, and of the final objectives to be met are the scope of the present paper.

  17. A Statistical Survey of Peculiar L and T Dwarfs in SDSS, 2MASS, and WISE

    Science.gov (United States)

    Kellogg, Kendra; Metchev, Stanimir; Miles-Páez, Paulo A.; Tannock, Megan E.

    2017-09-01

    We present the final results from a targeted search for brown dwarfs with unusual near-infrared colors. From a positional cross-match of the Sloan Digital Sky Survey (SDSS), 2-Micron All-Sky Survey (2MASS), and Wide-Field Infrared Survey Explorer (WISE) catalogs, we have identified 144 candidate peculiar L and T dwarfs. Spectroscopy confirms that 20 of the objects are peculiar or are candidate binaries. Of the 420 objects in our full sample 9 are young (≲ 200 {Myr}; 2.1%) and another 8 (1.9%) are unusually red, with no signatures of youth. With a spectroscopic J-{K}s color of 2.58 ± 0.11 mag, one of the new objects, the L6 dwarf 2MASS J03530419+0418193, is among the reddest field dwarfs currently known and is one of the reddest objects with no signatures of youth known to date. We have also discovered another potentially very-low-gravity object, the L1 dwarf 2MASS J00133470+1109403, and independently identified the young L7 dwarf 2MASS J00440332+0228112, which was first reported by Schneider and collaborators. Our results confirm that signatures of low gravity are no longer discernible in low to moderate resolution spectra of objects older than ˜200 Myr. The 1.9% of unusually red L dwarfs that do not show other signatures of youth could be slightly older, up to ˜400 Myr. In this case a red J-{K}s color may be more diagnostic of moderate youth than individual spectral features. However, its is also possible that these objects are relatively metal-rich, and thus have enhanced atmospheric dust content.

  18. Field Collection Methods for an EPA Pilot Study Evaluating ...

    Science.gov (United States)

    This compilation of field collection standard operating procedures (SOPs) was assembled for the U.S. Environmental Protection Agency’s (EPA) Pilot Study add-on to the Green Housing Study (GHS). A detailed description of this add-on study can be found in the peer reviewed research protocol entitled “An EPA Pilot Study Evaluating Personal, Housing, and Community Factors Influencing Children’s Potential Exposures to Indoor Contaminants at Various Lifestages –Research Protocol” 1. Briefly, the Centers for Disease Control and Prevention’s (CDC) Green Housing Study (GHS) follows changes in environmental measurements [pesticides, volatile organic compounds (VOCs), particulate matter (i.e., PM2.5 and 1.0), indoor allergens, and fungi] in both U.S. Department of Housing and Urban Development (HUD) green-renovated and comparison (no renovation) homes and relates these changes to asthma morbidity in children ages 7-12 years. Green-renovations include (but are not limited to) use of low VOC materials, use of energy efficient appliances, and integrated pest management. The EPA has leveraged this opportunity to collect additional multimedia measurements and questionnaire data from the index children actively participating in the GHS and a sibling in order to characterize personal, housing, and community factors. The purpose of this document is to publish the methodology EPA used for a specific study for reference and use by other scientists both within the Agency

  19. Association of experienced and evaluative well-being with health in nine countries with different income levels: a cross-sectional study.

    Science.gov (United States)

    Miret, Marta; Caballero, Francisco Félix; Olaya, Beatriz; Koskinen, Seppo; Naidoo, Nirmala; Tobiasz-Adamczyk, Beata; Leonardi, Matilde; Haro, Josep Maria; Chatterji, Somnath; Ayuso-Mateos, José Luis

    2017-08-23

    It is important to know whether the relationships between experienced and evaluative well-being and health are consistent across countries with different income levels. This would allow to confirm whether the evidence found in high income countries is the same as in low- and middle-income countries and to suggest policy recommendations that are generalisable across countries. We assessed the association of well-being with health status; analysed the differential relationship that positive affect, negative affect, and evaluative well-being have with health status; and examined whether these relationships are similar across countries. In this cross-sectional study, interviews were conducted amongst 53,269 adults from nine countries in Africa, Asia, Europe, and Latin America. Evaluative well-being was measured with a short version of the World Health Organization (WHO) Quality of Life instrument, and experienced well-being was measured with the Day Reconstruction Method. Decrements in health were assessed with the 12-item version of WHO Disability Assessment Schedule 2.0. Block-wise linear regression and structural equation models were employed. Considering the overall sample, evaluative well-being was more strongly associated with health (β = -0.35) than experienced well-being (β = -0.14), and negative affect was more strongly associated with health (β = 0.10) than positive affect (β = -0.02). The relationship between health and well-being was similar across countries. Lower scores in evaluative well-being and a higher age were the factors more strongly related with a worse health. The different patterns observed across countries may be related to differences in the countries' gross domestic product, social protection system, economic situation, health care provision, lifestyle behaviours, or living conditions. The fact that evaluative well-being is more predictive of health than experienced well-being suggests that our level of satisfaction with our

  20. Encouraging Stakeholder Engagement: A Case Study of Evaluator Behavior

    Science.gov (United States)

    Poth, Cheryl-Anne; Shulha, Lyn

    2008-01-01

    This chapter describes evaluator behaviors revealed by the case analysis of a participatory and developmental evaluation. The analysis revealed that the evaluator paid specific attention to individual stakeholder cues. These cues were related to three elements of the evaluation: negotiating the design, monitoring individual stakeholder needs, and…