WorldWideScience

Sample records for evaluation co-operation volume

  1. INTERNATIONAL CO-OPERATION IN NUCLEAR DATA EVALUATION

    Energy Technology Data Exchange (ETDEWEB)

    Herman, M.; Katakura,J.; Koning,A.; Nordborg,C.

    2010-04-30

    The OECD Nuclear Energy Agency (NEA) is organising a co-operation between the major nuclear data evaluation projects in the world. The co-operation involves the ENDF, JEFF, and JENDL projects, and, owing to the collaboration with the International Atomic Energy Agency (IAEA), also the Russian RUSFOND and the Chinese CENDL projects. The Working Party on international nuclear data Evaluation Cooperation (WPEC), comprised of about 20 core members, manages this co-operation and meets annually to discuss progress in each evaluation project and also related experimental activities. The WPEC assesses common needs for nuclear data improvements and these needs are then addressed by initiating joint evaluation efforts. The work is performed in specially established subgroups, consisting of experts from the participating evaluation projects. The outcome of these subgroups is published in reports, issued by the NEA. Current WPEC activities comprise for example a number of studies related to nuclear data uncertainties, including a review of methods for the combined use of integral experiments and covariance data, as well as evaluations of some of the major actinides, such as {sup 235}U and {sup 239}Pu. This paper gives an overview of current and planned activities within the WPEC.

  2. Upcrowding energy co-operatives - Evaluating the potential of crowdfunding for business model innovation of energy co-operatives.

    Science.gov (United States)

    Dilger, Mathias Georg; Jovanović, Tanja; Voigt, Kai-Ingo

    2017-08-01

    Practice and theory have proven the relevance of energy co-operatives for civic participation in the energy turnaround. However, due to a still low awareness and changing regulation, there seems an unexploited potential of utilizing the legal form 'co-operative' in this context. The aim of this study is therefore to investigate the crowdfunding implementation in the business model of energy co-operatives in order to cope with the mentioned challenges. Based on a theoretical framework, we derive a Business Model Innovation (BMI) through crowdfunding including synergies and differences. A qualitative study design, particularly a multiple-case study of energy co-operatives, was chosen to prove the BMI and to reveal barriers. The results show that although most co-operatives are not familiar with crowdfunding, there is strong potential in opening up predominantly local structures to a broader group of members. Building on this, equity-based crowdfunding is revealed to be suitable for energy co-operatives as BMI and to accompany other challenges in the same way. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. ITS for sustainable mobility: tools for designing and evaluating co-operative road-vehicle systems

    NARCIS (Netherlands)

    Baart, M.; Vink, W.; Horst, A.R.A. van der; Arem, B. van; Wilmink, I.

    2004-01-01

    Intelligent co-operative road-vehicle systems, in which intelligent road-side equipment co-operates with intelligent vehicles, have great potential to improve traffic flow safety, efficiency, reliability and quality of the environment. But what concepts for these systems are both realistic and

  4. Evaluation of Georgian military co-operation with partner countries and institutions / George Manjgaladze

    Index Scriptorium Estoniae

    Manjgaladze, George

    2003-01-01

    Ettekanne Gruusia sõjalis-poliitilisest koostööst välisriikide relvajõudude ja rahvusvaheliste organisatsioonidega, sh NATO-ga 22.-23. septembrini 2003 Vilniuses toimunud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO"

  5. Evaluation of bilateral and multilateral defence co-operation and assistance / Najaf Gambarov

    Index Scriptorium Estoniae

    Gambarov, Najaf

    2003-01-01

    Ettekanne Aserbaidžaani sõjalis-poliitilisest koostööst välisriikide relvajõududega ja rahvusvaheliste organisatsioonidega 22.-23. septembrini 2003 Vilniuses toimunud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO"

  6. Evaluation of bilateral and multilateral defence co-operation and assistance / Arthur Aghabekyan

    Index Scriptorium Estoniae

    Aghabekyan, Arthur

    2003-01-01

    Ettekanne Armeenia sõjalis-poliitilisest koostööst välisriikidega ja osalemisest rahvusvahelistes sõjalistes koostööprogrammides 22.-23. septembrini 2003 Vilniuses toimunud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO"

  7. Agricultural Co-Operatives in Ethiopia

    NARCIS (Netherlands)

    Tefera, Delelegne A.; Bijman, Jos; Slingerland, Maja A.

    2017-01-01

    To what extent can co-operatives strengthen rural development in sub-Saharan Africa? This paper explores the development of agricultural co-operatives in Ethiopia, particularly the changes in economic functions. Co-operative development in Ethiopia has been strongly influenced by various political

  8. Co-operatives and Normative Control

    DEFF Research Database (Denmark)

    Bregn, Kirsten; Jagd, Søren

    1992-01-01

    This paper explores the conditions for applying normative control in co-operatives. For normative control to be effective two conditions are found particularly important: Individuals must be morally involved and the organization must have a system of making it possible to link common norms...... and individual action. If these conditions are not fulfilled, as may be the case in many co-operatives, normative control cannot be expected to work. The problems of normative control in co-operatives may then not be caused by the use of normative control as such, but may instead be a problem of securing...... the conditions necessary for normative control. This is illustrated by a case study of control in a Danish producers co-operative. The analysis of the case study leads to the hypothesis of a paradox of normative control in co-operatives: The need of information tends to be greater in co-operatives comparet...

  9. Energy co-operatives in the UK

    OpenAIRE

    Y. Tham; T. Muneer

    2011-01-01

    The UK is implementing different types of policies to encourage the use of renewable energy for electricity generation. Currently, the UK is falling behind other European countries in this respect. Hence, co-operatives play an important role in helping the UK to move forward. Co-operatives are of interest to the Government in respect of economic development in the community. Co-operatives keep both the business, or entity, and the wealth it creates locally, which also supports the local econo...

  10. Agricultural Co-Operatives in Ethiopia

    OpenAIRE

    Tefera, Delelegne A.; Bijman, Jos; Slingerland, Maja A.

    2017-01-01

    To what extent can co-operatives strengthen rural development in sub-Saharan Africa? This paper explores the development of agricultural co-operatives in Ethiopia, particularly the changes in economic functions. Co-operative development in Ethiopia has been strongly influenced by various political regimes. Based on expert interviews and a literature review, we explore the factors that influence a shift in economic functions from provision of inputs to commercialization of farm products. Our r...

  11. Co-operation Amongst Polish Research Libraries

    Directory of Open Access Journals (Sweden)

    Ewa Dobrzyńska-Lankosz

    2007-11-01

    Full Text Available Polish research libraries have a long tradition of co-operating with one another, particularly when certain solutions require a collective effort. Co-operation can take place either at local, national or international level. In the past, we were able to observe close co-operation at the national level between libraries in similar disciplines (for instance, co-operation of groups of medical, technical and economics libraries. This form of co-operation has existed until today. Then, at the beginning of the 1990’s a new ‘configuration’ of library co-operation was initiated, that is, co-operation between libraries in various disciplines within one consortium aimed at choosing, purchasing and implementing the same integrated library system. The next step was co-operation undertaken within an inter-system consortium in order to fund a national union catalogue. This was an enormous enterprise, whose aim was to facilitate access to catalogue information on the collections of Polish research libraries and accelerate the process of cataloguing books. The National Union Catalogue NUKAT is based on shared cataloguing. At present, the catalogue is being created by 60 libraries, mainly academic.

  12. Making Co-Operative Ideas Work

    Science.gov (United States)

    Arnold, Phil

    2013-01-01

    Reddish Vale Technology College was the first co-operative trust in England. The democratic and co-operative nature of the experiment mean that students have gained a greater voice in the organisation of the school. As a result, new social enterprises, environmental interventions, connections with the community and with the wider co-operative…

  13. The Co-Operative: Good with Schools?

    Science.gov (United States)

    Coates, Max

    2015-01-01

    The article is a summary of a small-scale research project which considers the formation of Co-operative Trust Schools. This was carried out in 2013 at a time when the number of schools becoming Academies and Trust Schools through the Co-operative College was burgeoning. Through questionnaire, interview, documentary analysis and exploration of…

  14. The Shanghai Co-operation Organisation

    DEFF Research Database (Denmark)

    Hansen, Flemming Splidsboel

    New regional organisations are always interesting to follow as they will tell us more about the things that make or break this type of co-operation. Originally established as “The Shanghai Five” in 1996, The Shanghai Co-operation Organisation (SCO) has been successful at reducing tension between...

  15. Reasons to Co-Operate: Co-Operative Solutions for Schools

    Science.gov (United States)

    Roach, Patrick

    2013-01-01

    The NASUWT's landmark agreement with the Schools Co-operative Society has provided a new spur to co-operation, collaboration and collegiality in schools. Against a background of rapid and radical changes to the education landscape, co-operative schools are viewed by many as a means to maintaining public service ethos and values in education. The…

  16. Co-operative Research in Agricultural Economics

    OpenAIRE

    MacAulay, T. Gordon

    1988-01-01

    Co-operation in research is a complex question which would seem to depend to a large extent on a number of necessary and sufficient conditions for success. In this note an attempt is made to define some of these conditions and then reflect on a few possibilities for co-operation between institutions, in particular between government departments and universities. First, however, it is necessary to provide a brief discussion of research objectives.

  17. Strategic Stakeholder Communication and Co-operation in Environmental Management

    DEFF Research Database (Denmark)

    Madsen, Henning; Ulhøi, John Parm

    2002-01-01

    in this process is strategic stakeholder relationships like communication and co-operation. The paper addresses this topic based on a proposed approach for identifying and evaluating the influence from various groups of stakeholders as well as the findings from recent surveys of environmental management...

  18. Evaluation of water resources system vulnerability based on co-operative co-evolutionary genetic algorithm and projection pursuit model under the DPSIR framework

    Science.gov (United States)

    Zhao, Y.; Su, X. H.; Wang, M. H.; Li, Z. Y.; Li, E. K.; Xu, X.

    2017-08-01

    Water resources vulnerability control management is essential because it is related to the benign evolution of socio-economic, environmental and water resources system. Research on water resources system vulnerability is helpful to realization of water resources sustainable utilization. In this study, the DPSIR framework of driving forces-pressure-state-impact-response was adopted to construct the evaluation index system of water resources system vulnerability. Then the co-evolutionary genetic algorithm and projection pursuit were used to establish evaluation model of water resources system vulnerability. Tengzhou City in Shandong Province was selected as a study area. The system vulnerability was analyzed in terms of driving forces, pressure, state, impact and response on the basis of the projection value calculated by the model. The results show that the five components all belong to vulnerability Grade II, the vulnerability degree of impact and state were higher than other components due to the fierce imbalance in supply-demand and the unsatisfied condition of water resources utilization. It is indicated that the influence of high speed socio-economic development and the overuse of the pesticides have already disturbed the benign development of water environment to some extents. While the indexes in response represented lower vulnerability degree than the other components. The results of the evaluation model are coincident with the status of water resources system in the study area, which indicates that the model is feasible and effective.

  19. Co-operative leadership and higher education: four case studies

    OpenAIRE

    Neary, Mike; Venezuela Fuentes, Katia; Winn, Joss

    2017-01-01

    This paper reports on recent research into co-operative leadership which aims to support co-operative higher education; where co-operative education is understood as the connection between the co-operative movement and co-operative learning (Breeze 2011). The research was carried out in three co-operatives: a co-operative school, a co-operative university, a workers’ co-operative, and an employee owned retail business. The research is framed within a set of catalytic principles established in...

  20. Agricultural Productivity, Co-Operatives and Organisational ...

    African Journals Online (AJOL)

    Agricultural Productivity, Co-Operatives and Organisational Innovations: A Case of Selected Coffee Production Communities in Mbinga District Tanzania. ... The study objectives aimed at establishing coffee production level in the last farming season; examining the contribution of cooperative societies in the production of ...

  1. Nordic Model of Subregional Co-Operation

    Directory of Open Access Journals (Sweden)

    Grzela Joanna

    2017-12-01

    Full Text Available Nordic co-operation is renowned throughout the world and perceived as the collaboration of a group of countries which are similar in their views and activities. The main pillars of the Nordic model of co-operation are the tradition of constitutional principles, activity of public movements and organisations, freedom of speech, equality, solidarity, and respect for the natural environment. In connection with labour and entrepreneurship, these elements are the features of a society which favours efficiency, a sense of security and balance between an individual and a group. Currently, the collaboration is a complex process, including many national, governmental and institutional connections which form the “Nordic family”.

  2. Transnational Research Co-operation: Opportunities and Challenges for transnational research co-operation

    DEFF Research Database (Denmark)

    of the NGOs have a lot of international experience (mainly in Denmark and Germany) as partners in different co-operation projects. Almost all the NGOs have recognized the important role of the scientific information in their activity. NGOs also feel the need for an easy access to required information...... for transnational co-operation like: an investigation/project concerning the driving forces behind urban development,or a co-operation in the field of wastewater reuse and minimization of wastewater loads and discharge, or a service page (internet) to search for potential partners. The governmental institutions...... in order to improve transnational cooperation are identified to be: • Search for national/international project partners • Access to existent co-operation projects or networks • Develop in common project proposals on themes requested by community groups • Exchange information/good operational practices...

  3. Co-Operation: The Antidote to Isolated Misery

    Science.gov (United States)

    Jones, Sarah

    2013-01-01

    This is a case study demonstrating the impact the co-operative movement has had on one co-operative school in south-west England. Lipson Co-operative Academy in Plymouth was one of the first schools to convert to become a co-operative school in 2009. The article has been co-written by members of the Academy and focuses on three transformational…

  4. Do Co-operative Development Policies Really Lead to the ...

    African Journals Online (AJOL)

    This article assesses how Kenyan co-operative policies contribute to the development of co-operatives as viable business enterprises and autonomous democratic organisations. The article identifies three policy phases that have guided co-operative development over four decades. Policy engagement with cooperatives ...

  5. International solar energy research co-operation

    Energy Technology Data Exchange (ETDEWEB)

    Lund, P.; Peippo, K.; Konttinen, P. [Helsinki Univ. of Technology, Otaniemi (Finland). Advanced Energy Systems

    1998-10-01

    Finland has participated in several IEA activities during 1996-97. HUT coordinates the activities, but practical participation in collaborative actions take place both in industrial companies and research organisations. Neste Ltd has directly participated in several tasks and information of results has been disseminated more widely to Finnish industries and organisations. Co-operation projects covered here are: (1) IEA Photovoltaic Power Systems Task 1 `Information dissemination`, (2) IEA Photovoltaic Power Systems Task 3 `Use of Photovoltaic systems in Stand Alone and Island Applications`, (3) IEA Photovoltaic Power Systems Task 7 `Photovoltaics in built environment`, (4) IEA Solar Heating and Cooling Program Task 16 `Photovoltaics in buildings` and (5) IEA Working Group `Materials in Solar Thermal Collectors`

  6. Romanian-Danish Environmental Co-operation. Co-operation development 1993-1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The Danish Ministry of Environment and Energy has, since 1991, through the Danish Environmental Support Fund, contributed towards protecting the environment and nature in Central and Eastern European countries and has helped to limit regional as well as global pollution. The Romanian Ministry of Waters, Forests and Environmental Protection and the Danish Ministry of Environment and Energy initiated the co-operation in 1993 and an official Agreement was signed in 1994. This publication describes the co-operation between the two countries in the field of the environment in the hope that this will give both the general public of Romania and the international community a better understanding of the work being accomplished. It also gives an overview of the 19 projects developed within this framework, which has a total Danish grant of DKK 77.9 million. (au)

  7. Energy-efficient buildings program evaluations. Volume 2: Evaluation summaries

    Energy Technology Data Exchange (ETDEWEB)

    Lee, A.D.; Mayi, D.; Edgemon, S.D.

    1997-04-01

    This document presents summaries of code and utility building program evaluations reviewed as the basis for the information presented in Energy-Efficient Buildings Program Evaluations, Volume 1: Findings and Recommendations, DOE/EE/OBT-11569, Vol. 1. The main purpose of this volume is to summarize information from prior evaluations of similar programs that may be useful background for designing and conducting an evaluation of the BSGP. Another purpose is to summarize an extensive set of relevant evaluations and provide a resource for program designers, mangers, and evaluators.

  8. Co-operating for gold open access without APCs

    Directory of Open Access Journals (Sweden)

    Martin Paul Eve

    2015-03-01

    Full Text Available While article processing charges (APCs are emerging as a key way in which existing publishers can adapt to gold open access (OA, this mode is problematic in many ways. Considering the existing subscription publication ecosystem as a risk/cost-pooling mechanism leads to the conclusion that APCs are a concentration of risk that may come with damaging institutional consequences, particularly in the humanities disciplines. Consortial and co-operative modes of funding gold OA, however, do not come with these drawbacks but are susceptible to ‘free riders’. In this article, the theoretical backdrop to these models is addressed and the range of current offerings evaluated. Noting that classical economic incentives do not seem to operate in a world of inter-library loans, the article ends with a description of the model that is being implemented for the 'Open Library of Humanities' initiative, funded by the Andrew W Mellon Foundation.

  9. Understanding co-operative learning: a case study in tracing ...

    African Journals Online (AJOL)

    It describes how the students, through a co-operative learning process, researched and debated the question in four groups. The author's concerns that the students' view of educational practice might become inhibited by exposure to limited theories related to co-operative learning, were proven to be largely unfounded.

  10. Success parameters for housing co-operatives in South Africa

    Directory of Open Access Journals (Sweden)

    Jimoh Richard

    2012-12-01

    Full Text Available The roles of the various governments have been the driving force of the housing co-operatives in those countries due to the tremendous support received. The implication is that the housing co-operatives in any country cannot do it alone without the support of government in areas such as having legislation and policies, providing support services and embarking on regular education and training. The need to explore the housing co-operatives in South Africa with a view to determine the successes recorded over the years becomes imperative in order to advance strategies that will ensure virile and sustainable housing co-operatives. Results revealed that a lack of understanding exists as a result of inadequate information among government officials responsible for housing delivery and the public in the application of co-operative housing as a delivery approach. Also, inadequate training of co-operative members in leadership positions lead to a lack of administrative and management capabilities in the processes and operations of housing co-operatives. A pragmatic approach should be adopted so that legislation and policies that are beneficial to the housing co-operatives be enacted.

  11. The Austria-Czech Republic co-operation in the field of radiation-emergency preparedness.

    Science.gov (United States)

    Prouza, Z; Drabova, D; Moltasova, J; Hohenberg, J-K; Hofer, P

    2004-01-01

    An overview on the long-term information exchange and co-operation between Austria and the Czech Republic in the field of radiation emergency preparedness and evaluation of radiological consequences of NPP accidents is provided. Initiated by the 'Melk Protocol' between the Czech and Austrian governments in December 2000 and its follow-up activities, the information exchange and co-operation between the Czech Republic and Austria in the field of radiation-emergency preparedness have been extended. Among others, a Working Group to compare radiological consequences of Beyond Design Basis Accident with a detailed inter-comparison program concerning atmospheric dispersion models, dose assessment methods and counter- measures was established. Based on this experience, an area for future co-operation in the field of emergency preparedness and information exchange between the Czech Republic and Austria is discussed. Copyright 2004 Oxford University Press

  12. Co-operative or coyote? Producers’ choice between intermediary purchasers and Fairtrade and organic co-operatives in Chiapas

    OpenAIRE

    Milford, Anna Birgitte

    2014-01-01

    This study of organic and Fairtrade co-operatives in Mexico aims to find out why many coffee producers prefer not to join the certified co-operatives, despite their higher price offer. A study of costs of production of organic coffee concludes that it implies more work, but not necessarily higher yields. A main conclusion of the investigation is that the compulsory organic production methods deters many producers from entering the co-operatives, and that it is more attractive for producers wi...

  13. Further clarity on co-operation and morality

    OpenAIRE

    David S. Oderberg

    2017-01-01

    I explore the increasingly important issue of co-operation in immoral actions, particularly in connection with health care. Conscientious objection, especially as pertains to religious freedom in health care, has become a pressing issue in the light of the US Supreme Court judgment in Hobby Lobby. Section 2 outlines a theory of co-operation inspired by Catholic moral theologians such as those cited by the Court. The theory has independent plausibility and is at least worthy of serious conside...

  14. Co-operative learning and adaptive instruction in a mathematics curriculum

    NARCIS (Netherlands)

    Terwel, J.; Herfs, P.G.P.; Mertens, E.H.M.; Perrenet, J.Chr.

    1994-01-01

    The AGO 12 to 16 Project (the acronym AGO stands for the Dutch equivalent of 'Adaptive Instruction and Co-operative Learning') seeks to develop and evaluate a mathematics curriculum which is suitable for mixed-ability groups in secondary education. The research questions we will address here are,

  15. China and CERN renew their Co-operation Agreement

    CERN Multimedia

    2004-01-01

    Dr. Liu Yanhua, Chinese Vice Minister of Science and Technology, and Dr. Robert Aymar, Director-General of CERN, sign a new Co-operation Agreement between the Government of the People's Republic of China and CERN. During his visit to CERN on 17 February, Liu Yanhua, Vice Minister of Science and Technology of the People's Republic of China, signed a new Co-operation Agreement with the Laboratory. The Agreement, which is valid for a period of five years and renewable, lays down the framework for the development of scientific and technological co-operation between CERN and China. This includes China's participation, as a non-Member State, in CERN's research projects as well as its main programmes. Robert Aymar and Liu Yanhua underlined that this Agreement will provide an excellent framework for close co-operation on the LHC Programme and Grid and accelerator technologies. Scientific co-operation between China and CERN is nothing new, as Chinese physicists already took part in the LEP experiments. Today, CERN's C...

  16. New co-operation agreement between CERN and JINR

    CERN Document Server

    CERN Bulletin

    2010-01-01

    CERN Director-General Rolf Heuer (left) and JINR Director Alexei Sissakian (right). On Thursday 28 January, CERN Director-General Rolf Heuer and JINR Director Alexei Sissakian signed a new enlarged co-operation agreement to continue and enhance the scientific and technical co-operation of the two institutes in the field of high-energy physics. CERN and JINR have a long and successful history of collaboration extending back to the earliest days of their existence. The first informal meeting on international co-operation in the field of high-energy accelerators took place at CERN in 1959. It was attended by senior scientists from the United States, the USSR (including JINR) and CERN. Both JINR and CERN have played the role of a bridge between East and West for decades, contributing to the development of international scientific co-operation. In 1992 JINR signed a co-operation agreement with CERN that included an important number of protocols covering JINR’s participation in the construction of th...

  17. SMEs and their co-operation with academia.

    Science.gov (United States)

    Antoine, Jean Michel; Strömqvist, Mats

    2005-01-01

    Co-operation between SMEs and Academia can be a win-win situation when each partner understands the constraints of the other. SMEs are often leaders in innovation; therefore more ready to share interest in research. They are flexible and dynamic. They need a short feed-back to sustain their co-operation. Academia is often more long-term oriented and more question- than answer-oriented. A code of conduct can ease the relationship because it can anticipate the potential problems.

  18. FPGA Based Intelligent Co-operative Processor in Memory Architecture

    DEFF Research Database (Denmark)

    Ahmed, Zaki; Sotudeh, Reza; Hussain, Dil Muhammad Akbar

    2011-01-01

    benefits of PIM, a concept of Co-operative Intelligent Memory (CIM) was developed by the intelligent system group of University of Hertfordshire, based on the previously developed Co-operative Pseudo Intelligent Memory (CPIM). This paper provides an overview on previous works (CPIM, CIM) and realization......In a continuing effort to improve computer system performance, Processor-In-Memory (PIM) architecture has emerged as an alternative solution. PIM architecture incorporates computational units and control logic directly on the memory to provide immediate access to the data. To exploit the potential...

  19. "A model co-operative country": Irish-Finnish co-operative contacts at the turn of the twentieth century

    DEFF Research Database (Denmark)

    Hilson, Mary

    2017-01-01

    Agricultural co-operative societies were widely discussed across late nineteenth-century Europe as a potential solution to the problems of agricultural depression, land reform and rural poverty. In Finland, the agronomist Hannes Gebhard drew inspiration from examples across Europe in founding...... the Pellervo Society, to promote rural cooperation, in 1899. He noted that Ireland’s ‘tragic history’, its struggle for national self-determination and the introduction of co-operative dairies to tackle rural poverty, seemed to offer a useful example for Finnish reformers. This article explores the exchanges...... that even before the First World War it was Finland, not Ireland, that had begun to be regarded as ‘a model co-operative country’....

  20. Impact of Co-Operative Learning Strategies in English

    Science.gov (United States)

    Singaravelu, G.

    2010-01-01

    The study illuminates the effectiveness of Co-operative Learning Strategies in learning English Grammar for the learners at secondary level. Cooperative Learning is particularly beneficial for any student learning as a second language. It promotes peer interaction, which helps the development of language and the learning of concepts with content.…

  1. A marketing co-operative as a system of attributes

    NARCIS (Netherlands)

    W.J.J. Bijman (Jos); G.W.J. Hendrikse (George); C.P. Veerman (Cees)

    2000-01-01

    textabstractChanges in the market conditions for fruit and vegetables have induced Dutch co-operative auctions to restructure their sales and marketing activities. Nine auctions merged into VTN and established the marketing organisation The Greenery International BV. VTN/The Greenery have

  2. Co-operative employment education for target groups: solution to ...

    African Journals Online (AJOL)

    In recent times government has embarked on various programmes to solve the problem of unemployment. However only negligible number of people benefited from these programmes. This paper examines the need for co-operative employment education for target groups as a better solution to the problem of ...

  3. Towards co-operative governance in the development and ...

    African Journals Online (AJOL)

    This means that water policy is cross-sectoral, directly and indirectly affecting and affected by almost all other sectoral policies such as agriculture, urban development, rural development, health, housing, economic development. Effective implementation of any cross-sectoral policy requires that co-operative governance ...

  4. Aid Distribution and Co-operation in Unequal Communities

    NARCIS (Netherlands)

    Exelle, D' B.; Berg, van den M.M.

    2012-01-01

    We study the influence of economic inequality on co-operation and aid distribution in community-based development schemes. For this, we organized a field experiment in which community members contributed to a collective effort to attract aid. We find that devolving aid distribution to community

  5. Environmental co-operatives reconnect farming, ecology and society

    NARCIS (Netherlands)

    Ploeg, van der J.D.; Renting, H.

    2003-01-01

    Regional diversity, diversified farming styles and endogenous development are hot issues in the current political debate on European agriculture. This article presents a historical overview of development experiences and elaborates on the emergence of environmental co-operatives in Dutch farming.

  6. Military co-operation with South Caucasus countries / Rafal Seniuch

    Index Scriptorium Estoniae

    Seniuch, Rafal

    2003-01-01

    Ettekanne Poola ja Lõuna-Kaukaasia vabariikide vahelisest sõjalis-poliitilisest koostööst 22.-23. septembrini 2003 Vilniuses toimunud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO"

  7. The Study of European Co-operation and Practice of Co-operation in Russia (1890s-1920s)

    NARCIS (Netherlands)

    Novichenko, Irina

    2014-01-01

    The analysis of the central and local co-operative press (46 titles) of two chronological periods – before WWI (1910-1913) and before Revolution (1916-1917) permitted to reveal on which initiative the associations were established and how they worked with the towns/cities. In the aspect of the

  8. The Gowe Irrigation co-operative society and its role in Sanyati (Zimbabwe), 1967-1969

    OpenAIRE

    Nyandoro, M

    2007-01-01

    The paper focuses on the origins and development of agricultural co-operative societies in Zimbabwe since 1954 with particular reference to Gowe-Sanyati and evaluates their role in facilitating the channelling of production inputs to farmers and the marketing of their produce. It examines the criteria for eligibility to membership of such associations, namely who could belong and who could not, as well as their administrative structures and practices. In addition, the paper eva...

  9. BANKING SYSTEM STABILITY: COMMERCIAL AND CO-OPERATIVE BANKS

    Directory of Open Access Journals (Sweden)

    Dumitru-Cristian OANEA

    2014-04-01

    Full Text Available Commercial banks and co-operative banks are credit institutions, but there are some differences between the main operations proceeded by each of them. Based on these specific characteristics, we want to identify the manner in which financial crisis affected their activity. As we all know, the financial crisis had a major impact in the United States, the “natal” country of the crisis, because great banks such as Lehman Brothers or Merrill Lynch have bankrupted. Even if the Romanian banking system was not affected by such catastrophic situations, surely the financial crisis had a significant impact on it. This topic is worth to be analysed, because we would be able to identify the risk differences between these two types of business: commercial banks versus co-operative banks.

  10. Aid Distribution and Co-operation in Unequal Communities

    OpenAIRE

    Exelle, D', B.; Berg, van den, W.

    2012-01-01

    We study the influence of economic inequality on co-operation and aid distribution in community-based development schemes. For this, we organized a field experiment in which community members contributed to a collective effort to attract aid. We find that devolving aid distribution to community representatives increases the aid attracted, but that this benefits community representatives only. At the same time, however, community representatives do take fairness considerations into account. Th...

  11. International co-operation in the field of wind energy

    Energy Technology Data Exchange (ETDEWEB)

    Wolff, J. [VTT Energy, Espoo (Finland)

    1998-10-01

    The use of wind energy is expanding rapidly worldwide. At the end of 1996 over 6000 MW was installed and the annual increase has during the last years exceeded 1000 MW. The development is also reaching more and more countries. In order to maintain technical and commercial development international co-operation is needed to secure cost-effectiveness, reliability and safety of the technology. International recommendations, harmonisation and standardisation is promoted by several international organizations like IEA, IEC and the classification organisations

  12. A Pneumatic Tactile Sensor for Co-Operative Robots.

    Science.gov (United States)

    Gong, Daoxiong; He, Rui; Yu, Jianjun; Zuo, Guoyu

    2017-11-10

    Tactile sensors of comprehensive functions are urgently needed for the advanced robot to co-exist and co-operate with human beings. Pneumatic tactile sensors based on air bladder possess some noticeable advantages for human-robot interaction application. In this paper, we construct a pneumatic tactile sensor and apply it on the fingertip of robot hand to realize the sensing of force, vibration and slippage via the change of the pressure of the air bladder, and we utilize the sensor to perceive the object's features such as softness and roughness. The pneumatic tactile sensor has good linearity, repeatability and low hysteresis and both its size and sensing range can be customized by using different material as well as different thicknesses of the air bladder. It is also simple and cheap to fabricate. Therefore, the pneumatic tactile sensor is suitable for the application of co-operative robots and can be widely utilized to improve the performance of service robots. We can apply it to the fingertip of the robot to endow the robotic hand with the ability to co-operate with humans and handle the fragile objects because of the inherent compliance of the air bladder.

  13. Small-Volume Injections: Evaluation of Volume Administration Deviation From Intended Injection Volumes.

    Science.gov (United States)

    Muffly, Matthew K; Chen, Michael I; Claure, Rebecca E; Drover, David R; Efron, Bradley; Fitch, William L; Hammer, Gregory B

    2017-10-01

    In the perioperative period, anesthesiologists and postanesthesia care unit (PACU) nurses routinely prepare and administer small-volume IV injections, yet the accuracy of delivered medication volumes in this setting has not been described. In this ex vivo study, we sought to characterize the degree to which small-volume injections (≤0.5 mL) deviated from the intended injection volumes among a group of pediatric anesthesiologists and pediatric postanesthesia care unit (PACU) nurses. We hypothesized that as the intended injection volumes decreased, the deviation from those intended injection volumes would increase. Ten attending pediatric anesthesiologists and 10 pediatric PACU nurses each performed a series of 10 injections into a simulated patient IV setup. Practitioners used separate 1-mL tuberculin syringes with removable 18-gauge needles (Becton-Dickinson & Company, Franklin Lakes, NJ) to aspirate 5 different volumes (0.025, 0.05, 0.1, 0.25, and 0.5 mL) of 0.25 mM Lucifer Yellow (LY) fluorescent dye constituted in saline (Sigma Aldrich, St. Louis, MO) from a rubber-stoppered vial. Each participant then injected the specified volume of LY fluorescent dye via a 3-way stopcock into IV tubing with free-flowing 0.9% sodium chloride (10 mL/min). The injected volume of LY fluorescent dye and 0.9% sodium chloride then drained into a collection vial for laboratory analysis. Microplate fluorescence wavelength detection (Infinite M1000; Tecan, Mannedorf, Switzerland) was used to measure the fluorescence of the collected fluid. Administered injection volumes were calculated based on the fluorescence of the collected fluid using a calibration curve of known LY volumes and associated fluorescence.To determine whether deviation of the administered volumes from the intended injection volumes increased at lower injection volumes, we compared the proportional injection volume error (loge [administered volume/intended volume]) for each of the 5 injection volumes using a linear

  14. Economics of China's joint-stock co-operatives

    OpenAIRE

    Sun, Laixiang

    2001-01-01

    In the 1990s, a new ownership form called ‘joint-stock co-operative’ (gufen hezuozhi) became widely adopted in China’s township and village enterprise sector. The promising dynamics and high adaptive ability of the new ownership form is in contradiction with the conclusions suggested by the existing literature on industrial co-operatives and other types of employee ownership. To show the adaptive efficiency feature of the new form, this paper identifies and analyses the mechanisms that are de...

  15. International co-operation in a dental identification.

    Science.gov (United States)

    Kullman, L; Cipi, B

    1992-06-01

    A case of international identification of an unknown male, where the teeth were essential in establishing identity is described. A noteworthy aspect of the procedure was the teamwork between the police and other authorities, and the forensic odontologist and medical examiners in Albania and Sweden. In Albania a forensic medical examiner handled the dental examination, since forensic odontology is not yet acknowledged. The importance of having dental and medical ante-mortem registers for missing persons in every country is stressed. This is best administered in co-operation with the police authorities.

  16. The Effectiveness of Structured Co-Operative Teaching and Learning in Greek Primary School Classrooms

    Science.gov (United States)

    Kaldi, Stavroula; Filippatou, Diamanto; Anthopoulou, Barbara

    2014-01-01

    This study focuses upon the effectiveness of structured co-operative group work on primary school students, aged between 8.5 and 9.5 years old, regarding their content knowledge, attitudes towards co-operative group work, experiential learning and open-ended curriculum as well as students' social and learning behaviour during co-operative group…

  17. Social security systems in Tanzania: Phase II: Co-operatives and ...

    African Journals Online (AJOL)

    In the 1950s and 1960s Tanzania had the third largest co-operative movement in the world. These co-operatives provided economic and social protection to members so that poor peasants could sell their crops even in years of bad world market prices. The services provided by co-operatives, like education and trusteeship ...

  18. An Effect of the Co-Operative Network Model for Students' Quality in Thai Primary Schools

    Science.gov (United States)

    Khanthaphum, Udomsin; Tesaputa, Kowat; Weangsamoot, Visoot

    2016-01-01

    This research aimed: 1) to study the current and desirable states of the co-operative network in developing the learners' quality in Thai primary schools, 2) to develop a model of the co-operative network in developing the learners' quality, and 3) to examine the results of implementation of the co-operative network model in the primary school.…

  19. The Architecture of Co-operation : A Project for organizing collective creativity

    NARCIS (Netherlands)

    Borra, B.

    2014-01-01

    The Architecture of Co-operation investigates the relationship between the collective subject and urban form through co-operation as means of production. The point is how individuals can organize co-operation today for the city as a project and what could be the role of architects into this process.

  20. New Zealand signs up to co-operate with CERN

    CERN Multimedia

    Patrice Loïez

    2003-01-01

    On 4 December 2003 a Memorandum of Understanding (MoU) between CERN and the government of New Zealand was signed in the presence of Peter Hamilton, New Zealand's ambassador to Switzerland. This MoU concerns the further development of scientific and technical co-operation in high-energy particle physics between Ernest Rutherford's birthplace and CERN, which now hosts one of the world's most ambitious scientific endeavours, the Large Hadron Collider (LHC).    In anticipation of the MoU, two New Zealand universities (the University of Auckland and the University of Canterbury in Christchurch) have already joined the CMS collaboration to work on pixel detectors, where they can benefit from the expertise of the pixel group at the Paul Scherrer Institute. These detectors are not only valuable in high-energy particle physics, but also serve medical applications.

  1. Protocol to co-operation agreement with Iran

    CERN Document Server

    2001-01-01

    A Co-operation Agreement between CERN and Iran will be signed in the coming weeks within the framework of the decisions taken by the Committee of Council and Council in June 1989. In view of implementing this Agreement, a Protocol between CERN and the International Scientific Meetings Office of the Ministry of Science of the Islamic Republic of Iran has been drawn up. It concerns the participation of scientific Institutions of Iran in the CMS Collaboration where CERN is acting on behalf of this Collaboration. This Protocol incorporates the agreement between CMS and ISMO on the Iranese contribution. It does not involve any financial commitment for CERN. The Protocol mainly addresses the status of the Iranese scientists at CERN, the supply by ISMO of the support tables for CMS, as well as the usual provisions concerning delivery and customs, guarantees, responsibilities, intellectual property and disputes. This Protocol is submitted to the Finance Committee for information.

  2. Cross-border mergers between agricultural co-operatives -a governance perspective

    DEFF Research Database (Denmark)

    Nilsson, Jerker; Madsen, Ole Øhlenschlæger

    A merger between agricultural co-operatives involves two merger processes - one concerningthe two co-operative business firms and the other concerning the two co-operative societies,i.e., the ownership organisations. These two merger processes are mutually dependent. If amerger involves co......-operatives in different countries, each with its own institutional structures,farming conditions, legal framework, and other attributes, the merger between the cooperativesocieties is due to be difficult, requiring large efforts to attain the necessary degreeof homogeneity. At the same time it must be recognised......-border mergers between agricultural co-operatives....

  3. Signature of the Co-operation Agreement between CERN and JINR, Dubna concerning Scientific and Technical Co-operation in High-Energy Physics

    CERN Multimedia

    Maximilien Brice

    2010-01-01

    On Thursday 28 January, CERN Director-General Rolf Heuer and JINR Director Alexei Sissakian signed a new enlarged co-operation agreement to continue and enhance the scientific and technical co-operation of the two institutes in the field of high-energy physics.

  4. Volume uterino em adolescentes avaliado pela ultra-sonografia Uterine volume in teenagers evaluated by ultrasound

    Directory of Open Access Journals (Sweden)

    Francisco Mauad Filho

    2003-01-01

    Full Text Available OBJETIVO: avaliar o volume uterino de mulheres entre 10 e 40 anos, verificando-se se o volume uterino de adolescentes é menor que o volume uterino de mulheres entre 20 e 40 anos. Procuram-se enfatizar as diferenças entre o volume uterino de adolescentes e mulheres adultas correlacionando-as com a imaturidade do trato genital de adolescentes para a gravidez e o parto. MÉTODOS: estudo transversal, no qual 828 pacientes entre 10 e 40 anos foram divididas em dois grupos e avaliadas por meio da ultra-sonografia transabdominal para aferição do volume uterino. O primeiro grupo (Ad foi formado por 477 (57,7% adolescentes e o segundo grupo (Ma por 351 (42,3% mulheres adultas entre 20 e 40 anos. No grupo Ad, os exames ultra-sonográficos foram realizados por um único observador e no grupo Ma, por um grupo de médicos que seguiram a mesma metodologia utilizada no grupo Ad. Os aparelhos ultra-sonográficos utilizados foram Image Point HX (Hewlett Packard e Hitachi 525, com transdutor convexo multifreqüencial. O cálculo do volume uterino foi obtido pelos diâmetros longitudinal (DL, ântero-posterior (DAP e transverso (DT, multiplicados pela constante 0,45. RESULTADOS: o volume uterino de adolescentes entre 10 e 17 anos foi menor que o volume uterino de mulheres entre 20 e 40 anos (p0,05. CONCLUSÃO: o volume uterino de adolescentes com menos de 18 anos ou primíparas é menor que o volume uterino de mulheres entre 20 e 40 anos. Entretanto, adolescentes com 18 anos ou mais, ou secundíparas, têm volume uterino similar ao volume uterino de mulheres entre 20 e 40 anos.PURPOSE: to evaluate the uterine volume in women between 10 and 40 years in order to observe if the uterine volume in adolescents is smaller than the uterine volume in women between 20 and 40 years. We intend to emphasize the differences between the uterine volume of adolescents and that of adult women and to correlate with the immaturity of the genital tract of adolescents regarding

  5. [Sex role orientation and interdisciplinary co-operation].

    Science.gov (United States)

    Kada, Olivia; Brunner, Eva; Maier, Marco

    2010-01-01

    Interdisciplinary collaboration between nurses and physicians contributes to optimal patient outcomes. Both insufficient knowledge of each other's roles and competencies and the power position of physicians impede nurse-physician collaboration. Health care managers play an important role in the promotion of nurse-physician collaboration. Leadership is associated with masculine traits, but female attributes are crucial in social relationships. Austrian health care management students (n=141, response rate: 93 %) rated themselves, the typical nurse and the typical physician with respect to masculine and feminine traits using the Bem sex-role-inventory (BSRI). The respondents saw themselves as equally masculine and feminine (androgynous self-concept); nurses were rated as significantly more masculine than feminine, whereas physicians were described as masculine sex-typed and significantly less feminine than nurses. For health care managers who also have to promote interdisciplinary collaboration an androgynous self-concept can be regarded as advantageous. They need to reflect on their ideas about nurses and physicians in order to manage the challenge of promoting interprofessional co-operation. Copyright © 2010. Published by Elsevier GmbH.

  6. Energy Technology Initiatives - Implementation Through Multilateral Co-operation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-15

    New technologies will be critical in addressing current global energy challenges such as energy security. More must be done, however, to push forward the development and deployment of the technologies we need today and will need in the future. Government leaders have repeatedly underlined the crucial role of industry and businesses in advancing energy technologies and the importance of strong collaboration among all stakeholders to accelerate technology advances. To attain these goals, increased co-operation between industries, businesses and government energy technology research is indispensable. The public and private sectors must work together, share burdens and resources, while at the same time multiplying results and outcomes. The 42 multilateral technology initiatives (Implementing Agreements) supported by the IEA are a flexible and effective framework for IEA member and non-member countries, businesses, industries, international organisations and non-government organisations to research breakthrough technologies, to fill existing research gaps, to build pilot plants, to carry out deployment or demonstration programmes -- in short to encourage technology-related activities that support energy security, economic growth and environmental protection. This publication highlights the significant accomplishments of the IEA Implementing Agreements.

  7. FIELD EVALUATION OF A HIGH-VOLUME DICHOTOMOUS SAMPLER

    Science.gov (United States)

    This study presents the field evaluation of a high-volume dichotomous sampler that collects coarse (PM10-2.5) and fine (PM2.5) particulate matter. The key feature of this device is the utilization of a round-nozzle virtual impactor with a 50% cutpoint at 2.5 5m to split PM10 into...

  8. Evaluation of surface quality by Fractal Dimension and Volume ...

    African Journals Online (AJOL)

    This study aims, the evaluation of the surface quality by the fractal dimension "D" and volume settings (Vmp, Vmc, Vvv). Experimental work was conducted by process of surface mechanical treatment; in this case ball burnishing was applied on a commercial aluminum alloy material. Three parameters of regime were ...

  9. Relative Evaluation of the Independent Volume Measures of Caverns

    Energy Technology Data Exchange (ETDEWEB)

    MUNSON,DARRELL E.

    2000-08-01

    Throughout the construction and operation of the caverns of the Strategic Petroleum Reserve (SPR), three types of cavern volume measurements have been maintained. These are: (1) the calculated solution volume determined during initial construction by solution mining and any subsequent solutioning during oil transfers, (2) the calculated sonar volume determined through sonar surveys of the cavern dimensions, and (3) the direct metering of oil to determine the volume of the cavern occupied by the oil. The objective of this study is to compare these measurements to each other and determine, if possible, the uncertainties associated with a given type of measurement. Over time, each type of measurement has acquired a customary, or an industry accepted, stated uncertainty. This uncertainty is not necessarily the result of a technical analysis. Ultimately there is one definitive quantity, the oil volume measure by the oil custody transfer meters, taken by all parties to the transfer as the correct ledger amount and for which the SPR Project is accountable. However, subsequent transfers within a site may not be with meters of the same accuracy. In this study, a very simple theory of the perfect relationship is used to evaluate the correlation (deviation) of the various measures. This theory permits separation of uncertainty and bias. Each of the four SPR sites are examined, first with comparisons between the calculated solution volumes and the sonar volumes determined during construction, then with comparisons of the oil inventories and the sonar volumes obtained either by surveying through brine prior to oil filling or through the oil directly.

  10. Analysis on the Load Carrying Mechanism Integrated as Heterogeneous Co-operative Manipulator in a Walking Wheelchair

    Science.gov (United States)

    Rajay Vedaraj, I. S.; Jain, Ritika; Rao, B. V. A.

    2014-07-01

    After industrial robots came into existence during 1960, the technology of robotics with the design and analysis of robots in various forms in industries as well as in domestic applications were developed. Nowadays, along with the automotive sector the robots are producing a great impact in the form of quality and production rate to register their existence reliable in various other sectors also. Robotic technology has undergone various phase translations from being tortured as humanoids to the present day manipulators. Depending upon the various forms of its existence, robot manipulators are designed as serial manipulators and parallel manipulators. Individually both types can be proved effective though both have various drawbacks in design and the kinematic analysis. The versatility of robots can be increased by making them work in an environment where the same work volume is shared by more than one manipulator. This work volume can be identified as co-operative work volume of those manipulators. Here the interference of manipulators in the work volume of other manipulators is possible and is made obstacle free. The main advantage of co-operative manipulators is that when a number of independent manipulators are put together in a cooperative work envelope the efficiency and ability to perform tasks is greatly enhanced. The main disadvantage of the co-operative manipulators lies in the complication of its design even for a simple application, in almost all fields. In this paper, a cooperative design of robot manipulators to work in co-operative work environment is done and analysed for its efficacy. In the industrial applications when robotic manipulators are put together in more numbers, the trajectory planning becomes the tough task in the work cell. Proper design can remove the design defects of the cooperative manipulators and can be utilized in a more efficient way. In the proposed research paper an analysis is made on such a type of cooperative manipulator

  11. 'Part of the solution': Developing sustainable energy through co-operatives and learning

    Science.gov (United States)

    Duguid, Fiona C. B.

    After five years of development, WindShare Co-operative in Toronto, Ontario became the first urban wind turbine in North America and the first co-operatively owned and operated wind turbine in Canada. The development of WindShare Co-operative has spurred the growth of a green energy co-operative sector in Ontario. This study, which included 27 interviews and a focus group with members of WindShare Co-operative, focuses on the roles of community-based green energy co-operatives in advancing sustainable energy development and energy literacy. Sustainable energy development is firmly rooted in the triple bottom line of environmental, social and economic success, and green energy co-operatives can be a way to help achieve those successes. Green energy co-operatives are structures for providing renewable energy generation or energy conservation practices, both of which have important environmental impacts regarding climate change and pollution levels. Co-operative structures are supported by processes that include local ownership, democracy, participation, community organizing, learning and social change. These processes have a significant social impact by creating a venue for people to be directly involved in the energy industry, by involving learning through participation in a community-based organization, and by advancing energy literacy within the membership and the general public. In regards to the economic impacts, green energy co-operatives foster a local economy and local investment opportunities, which have repercussions regarding building expertise within Ontario's green energy and co-operative development future, and more generally, captures members' interest because they have a direct stake in the co-operative. This thesis shows that green energy co-operatives, like WindShare, play an important role in advancing sustainable energy development, energy literacy and the triple bottom line. Members of WindShare expressed resounding feelings of pride, efficacy

  12. [Use of ultrasound for gastric volume evaluation after ingestion of different volumes of isotonic solution].

    Science.gov (United States)

    Bisinotto, Flora Margarida Barra; Naves, Aline de Araújo; Lima, Hellen Moreira de; Peixoto, Ana Cristina Abdu; Maia, Gisele Caetano; Resende Junior, Paulo Pacheco; Martins, Laura Bisinotto; Silveira, Luciano A Matias da

    The current preoperative fasting guidelines allow fluid intake up to 2hours before surgery. The aim of this study was to evaluate the gastric volume of volunteers after an overnight fast and compare it with the gastric volume 2hours after ingestion of 200 and 500mL of isotonic solution, by means of ultrasound assessment. Eighty volunteers underwent gastric ultrasound at three times: after 8hours of fasting; 2hours after ingestion of 200mL isotonic saline, followed by the first scan; and on another day, 2hours after ingestion of 500mL of the same solution after an overnight fast. The evaluation was quantitative (antrum area and gastric volume, and the ratio of participants' gastric volume/weight) and qualitative (absence or presence of gastric contents on right lateral decubitus and supine positions. A p-value0.05). Five volunteers (6.25%) had a volume/weight over 1.5mL.kg -1 at fasting and 2hours after ingestion of 200mL and 6 (7.5%) after 500mL. Qualitatively, the presence of gastric fluid occurred in more volunteers after fluid ingestion, especially 500mL (18.7%), although not statistically significant. Ultrasound assessment of gastric volume showed no significant difference, both qualitative and quantitative, 2h after ingestion of 200mL or 500mL of isotonic solution compared to fasting, although gastric fluid content has been identified in more volunteers, especially after ingestion of 500mL isotonic solution. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

  13. Use of ultrasound for gastric volume evaluation after ingestion of different volumes of isotonic solution

    Directory of Open Access Journals (Sweden)

    Flora Margarida Barra Bisinotto

    Full Text Available Abstract Background and objectives: The current preoperative fasting guidelines allow fluid intake up to 2 h before surgery. The aim of this study was to evaluate the gastric volume of volunteers after an overnight fast and compare it with the gastric volume 2 h after ingestion of 200 and 500 mL of isotonic solution, by means of ultrasound assessment. Method: Eighty volunteers underwent gastric ultrasound at three times: after 8 h of fasting; 2 h after ingestion of 200 mL isotonic saline, followed by the first scan; and on another day, 2 h after ingestion of 500 mL of the same solution after an overnight fast. The evaluation was quantitative (antrum area and gastric volume, and the ratio of participants’ gastric volume/weight and qualitative (absence or presence of gastric contents on right lateral decubitus and supine positions. A p-value 0.05. Five volunteers (6.25% had a volume/weight over 1.5 mL kg-1 at fasting and 2 h after ingestion of 200 mL and 6 (7.5% after 500 mL. Qualitatively, the presence of gastric fluid occurred in more volunteers after fluid ingestion, especially 500 mL (18.7%, although not statistically significant. Conclusion: Ultrasound assessment of gastric volume showed no significant difference, both qualitative and quantitative, 2 h after ingestion of 200 mL or 500 mL of isotonic solution compared to fasting, although gastric fluid content has been identified in more volunteers, especially after ingestion of 500 mL isotonic solution.

  14. Regional higher education co-operation: a research proposal to compare the Baltic Sea and the Black Sea regions

    Directory of Open Access Journals (Sweden)

    Stefan Ewert

    2011-12-01

    Full Text Available While the Baltic Sea Region is considered to be a pioneer region in the development of regional integration and identity, the Black Sea Region is regarded to be a laggard in terms of regionali¬zation and region building. My paper summarizes the role of regional higher education co-operation in the Baltic Sea regionalization process in theory and analyzes the empirical background of these assumptions. Yet, inasmuch an evaluation of the regions` status as a pioneer is possible only in a comparative perspective, I propose to compare the Black Sea and the Baltic Sea Region regarding their higher education networks systematically. My paper asks for the transferability of arguments in favor of a strong regional higher education co-operation in the Baltic Sea Region since the 1990s to today’s situation of the Black Sea Region. It concludes with some fundamental considerations on a comparative research project.

  15. Co-Operative Problem-Solving at the Royal Docks Community School

    Science.gov (United States)

    Martin, Ruth

    2013-01-01

    This article responds to Henry Tam's article in this issue of FORUM by exploring opportunities for co-operative problem-solving for staff and students of the Royal Docks Community School in the London Borough of Newham. Becoming a co-operative trust helped the school move out of special measures and develop a strategy of participation and…

  16. Co-Operative Education and the State, c.1895-1935

    Science.gov (United States)

    Vernon, Keith

    2013-01-01

    The co-operative movement is currently exploring ways of engaging with changes in government education policy to develop schools with a distinctive co-operative ethos. While drawing on the opportunities in changing policy, these initiatives can also be seen as offering alternatives to the prevailing tenor of government thinking. This is not the…

  17. Fostering Positive Peer Relations in the Primary Classroom through Circle Time and Co-Operative Games

    Science.gov (United States)

    Mary, Latisha

    2014-01-01

    The aim of this study was to investigate the role of co-operative games and circle time activities in fostering positive peer relations in two French Primary classrooms (N = 40). It presents French teachers' and pupils' perceptions of a set of co-operative games and circle time activities implemented within a year long study on personal, social…

  18. Co-Operative Schools: Building Communities in the 21st Century

    Science.gov (United States)

    Woodin, Tom

    2012-01-01

    The recent progress of "co-operative schools" both confirms and disrupts many assumptions surrounding contemporary compulsory schooling. The term itself refers to an eclectic array of schools, both primary and secondary, of which there were, by June 2012, almost 300 in England that have adopted co-operative values, in terms of…

  19. Effectiveness of Co-Operative Learning Method in Learning of Mathematics among Eighth Standard Students

    Science.gov (United States)

    Kaliappan, Thiyagu

    2012-01-01

    Co-operative learning is defined as students working together to "attain groups goals that cannot be obtained by working alone or competitively." The main purpose of co-operative learning is to actively involve students in the learning process, a level of student empowerment which is not possible in a lecture format. The present study…

  20. Using Critical Problem Solving to Plan Inter-Organisational Co-operation in e-Customs

    NARCIS (Netherlands)

    Ponisio, Laura; van Eck, Pascal; Riemens, L.

    The purpose of this paper is to present a systematic approach to plan assessment of electronic co-operation between customs organisations of different countries (e-Customs). Thorough assessment is of paramount importance, as co-operation in electronic networks usually requires considerable up-front

  1. Success and failure of firms' innovation co-operations: The role of intermediaries and reciprocity

    DEFF Research Database (Denmark)

    Cantner, U.; Meder, A.; Wolf, T.

    2011-01-01

    attempts to fill this gap by investigating the possible presence of two problems in co-operation: the lack of intermediation and of reciprocity. Based on data gathered for firms in two German regions and one French region, we find that the success of co-operation projects depends on the perceived...

  2. Super Efficient Refrigerator Program (SERP) evaluation. Volume 1: Process evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Sandahl, L.J.; Ledbetter, M.R.; Chin, R.I.; Lewis, K.S.; Norling, J.M.

    1996-01-01

    The Pacific Northwest National Laboratory (PNNL) conducted this study for the US Department of Energy (DOE) as part of the Super Efficient Refrigerator Program (SERP) Evaluation. This report documents the SERP formation and implementation process, and identifies preliminary program administration and implementation issues. The findings are based primarily on interviews with those familiar with the program, such as utilities, appliance manufacturers, and SERP administrators. These interviews occurred primarily between March and April 1995, when SERP was in the early stages of program implementation. A forthcoming report will estimate the preliminary impacts of SERP within the industry and marketplace. Both studies were funded by DOE at the request of SERP Inc., which sought a third-party evaluation of its program.

  3. Proceedings of International Symposium on Energy Co-operation in North East Asia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-06-01

    This proceedings are for the International Symposium on Energy Co-operation in North-East Asia, organized by Korea Energy Economics Institute, Institute of Energy Economics, Japan, and United Nations Economic and Social Commission for Asia and the Pacific, held on June 2001 at Sheraton Walker Hill Hotel in Seoul, Korea. The major themes discussed are following: 1.Energy Profile, Outlook and Perspectives on Regional Co-operation in Northeast Asia 2.Future Challenges in the Energy Sector in Northeast Asia 3.Perspectives of Energy Co-operation in Northeast Asia.

  4. Co-operation agreement between the European Organization for Nuclear Research (CERN) and the Government of People's Republic of Bangladesh concerning Education, Scientific and Technical Co-operation in High-Energy Physics

    CERN Document Server

    2014-01-01

    Co-operation agreement between the European Organization for Nuclear Research (CERN) and the Government of People's Republic of Bangladesh concerning Education, Scientific and Technical Co-operation in High-Energy Physics

  5. Forest owners' energy co-operatives as energy producers

    Energy Technology Data Exchange (ETDEWEB)

    Tyynelae, T. (Finnish Forest Research Inst., Kannus (Finland)), e-mail: tapani.tyynela@metla.fi

    2010-07-01

    The aim of this presentation is to describe energy co-operative member and general public opinions on the key issues limiting energy wood demand. This data will act as background information for the development of business models for energy co-operatives and their members in Central Ostrobothnia, Finland. Our results from the survey among the general public showed clearly that people are willing to support energy co-operatives in their aims to increase energy production. Also, public opinion supports subsidies from the government so that energy wood production would be more profitable. The second survey made for the members shows that the co-operatives had some differences in their members' occupations and in the mean forest estate areas. There were also differences in the mean ages and levels of information delivered to the members, but they were not very significant. However, all this background information must be taken into account when new business models are developed. (orig.)

  6. Organization for security and co-operation in Europe mission to Georgia / Joe McDonagh

    Index Scriptorium Estoniae

    McDonagh, Joe

    2003-01-01

    22.-23. septembrini 2003 Vilniuses toimunud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO" esitatud ettekanne OSCE missiooni tegevusest Gruusias

  7. Human factors evaluation of teletherapy: Literature review. Volume 5

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, K.; Kaye, R.D.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.L. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations were undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multidisciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation therapists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was performed initially to guide subsequent evaluations in the areas of workplace environment, system-user interfaces, procedures, training, and organizational practices. To further acquire an in-depth and up-to-date understanding of the practice of teletherapy in support of these evaluations, a systematic literature review was conducted. Factors that have a potential impact on the accuracy of treatment delivery were of primary concern. The present volume is the literature review. The volume starts with an overview of the multiphased nature of teletherapy, and then examines the requirement for precision, the increasing role of quality assurance, current conceptualizations of human error, and the role of system factors such as the workplace environment, user-system interfaces, procedures, training, and organizational practices.

  8. Competition and Co-operation between Stock Exchanges in Europe - Legal Aspects and Challenges

    DEFF Research Database (Denmark)

    Sørensen, Karsten Engsig; Clausen, Nis Jul

    2002-01-01

    The article analysis why and how European Stock Exchanges enters into alliances. On the background of alliances as Norex, Euronext and the planned iX the different areas and types of co-operation is discussed.......The article analysis why and how European Stock Exchanges enters into alliances. On the background of alliances as Norex, Euronext and the planned iX the different areas and types of co-operation is discussed....

  9. Local and Sustainable Food Supply: The Role of European Retail Consumer Co-operatives

    Directory of Open Access Journals (Sweden)

    Martin Hingley

    2012-03-01

    Full Text Available  This paper investigates the rationale for local and sustainable food systems and retailer co-operatives as their entry points within local conditions. Emphasis is on localised food networks and connection between socially as well as environmentally sustainable production, distribution and consumption. Investigated is the premise that co-operative organisational structures, for reasons of their long-term socially responsible origins are at the forefront of development of local and sustainable food systems and are thereby in a position to offer a specific contribution to market development. Two key research questions are proposed: Firstly, is there a pre-determination of co-operatives to issues of sustainable and local food sourcing given the historical and practical context of their ethical/socially responsible and stakeholder-based business model? Secondly, do co-ops express support for re-localising food systems and what contribution do they make concerning sustainable food and their relationships with local food suppliers? The method of investigation is through a two country retailer co-operative sector analysis and comparison (Finland and Italy. The enquiry is qualitative and exploratory in nature in the form of an embedded, multiple case design. The paper makes practical and theoretical contribution to knowledge concerning interpretation of ‘localness’ in food, the role of co-operatives and the co-operative ethos in sustainable food systems and the development of the local food economy. Results of the study show a positive relationship between co-operative ethos and (social sustainability in local food, but the de-centralised nature of retailer co-operation also provides a barrier to replication of good practice.

  10. Health Services in Denmark: Co-operation between different sectors?

    DEFF Research Database (Denmark)

    Singla, Rashmi

    focuses on different categories of societal exclusion: ageism, sexism as well as racism experienced by migrants, involving the minorities both in planning and evaluation.   These practices justify my placing of Denmark in the middle position on a continuum on one end with “Top down” approach in Holland...

  11. South Asian co-operation in population programmes.

    Science.gov (United States)

    Iqbal, M A

    1989-12-01

    Efforts by governments of South Asian countries to improve the economic growth and welfare of the people are being negated by high fertility. In some countries, the expenditures on health programs have increased and the programs have expanded rapidly without any concomitant improvement in efficiency or cost-effectiveness. This highlights the urgency of tackling the problems of not only population growth but also of managing population programs. There are similarities as well as differences in the management of population programs in the South Asian countries. Bangladesh has a population policy with a strong political will behind it. It also has a sound administrative structure and organization. Some areas that need attention are building up the operational relationship between health and family planning personnel, improved infrastructure development, more community involvement, and better evaluation. Some states in India have shown outstanding success in population programs, and some have successfully experimented with beyond family planning methods. A greater awareness of family planning among health staff, a solid information base for decision making, and management training for medical officers and staff are also needed. Pakistan's population program has had uneven results in the past, but it has now developed multi-sectoral components in decentralized field activities, involvement of local organizations and leaders, and better information, education, and social marketing, but it still needs to plan for evaluation and strengthen management training. Of the South Asian countries, Sri Lanka, with a high level of literacy and health care, has shown the best achievement in its social sector. The coverage through the maternal and child health service delivery system has been commendable with 94% of deliveries through institutions. Regional meetings have identified program management problem areas in 1) planning, control, and coordination of program implementation, 2

  12. A framework for evaluation of technology transfer programs. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    The objective of this volume is to describe a framework with which DOE can develop a program specific methodology to evaluate it`s technology transfer efforts. This approach could also be applied to an integrated private sector technology transfer organization. Several benefits will be realized from the application of this work. While the immediate effect will be to assist program managers in evaluating and improving program performance, the ultimate benefits will accrue to the producing industry, the states, and the nation in the form of sustained or increased domestic oil production. This benefit depends also, of course, on the effectiveness of the technology being transferred. The managers of the Technology Transfer program, and the larger federal oil and gas R&D programs, will be provided with a means to design and assess the effectiveness of program efforts as they are developed, tested and performed. The framework allows deficiencies in critical aspects of the program to be quickly identified, allowing for timely corrections and improvements. The actual process of developing the evaluation also gives the staff of the Oil R&D Program or Technology Transfer subprogram the opportunity to become oriented to the overall program goals. The structure and focus imposed by the evaluation paradigm will guide program staff in selecting activities which are consistent with achieving the goals of the overall R&D program.

  13. Left ventricular volume measurement in mice by conductance catheter: evaluation and optimization of calibration

    DEFF Research Database (Denmark)

    Nielsen, Jan Møller; Kristiansen, Steen B; Ringgaard, Steffen

    2007-01-01

    The conductance catheter (CC) allows thorough evaluation of cardiac function because it simultaneously provides measurements of pressure and volume. Calibration of the volume signal remains challenging. With different calibration techniques, in vivo left ventricular volumes (V(CC)) were measured...... in mice (n = 52) with a Millar CC (SPR-839) and compared with MRI-derived volumes (V(MRI)). Significant correlations between V(CC) and V(MRI) [end-diastolic volume (EDV): R(2) = 0.85, P

  14. Brayton isotope power system. Volume II. System evaluation attributes

    Energy Technology Data Exchange (ETDEWEB)

    1978-03-15

    This volume of the Brayton Isotope Power System, Phase II Plan, contains the self-evaluation by AiResearch, GE, and TECO, addressing Section 3 of The Dynamic Systems Evaluation Criteria and Procedures established by the Department of Energy. These evaluation criteria addresses: Component Feasibility; Flight System Design Performance; GDS Test Results; Reliability and Practicality; Safety; Spacecraft Integration; and Cost and Risk. Included in each of these general categories are several attributes, each of which addresses a separate component, feature, or area of interest related to the power system, its development status, degree of preparedness for proceeding into a flight program, and/or the contractors' performance during Phase I. The key elements which indicate the readiness of a radioisotope power system to progress into a flight qualification program are: an advanced state of development of the power conversion system; demonstrated or exhibited potential for space systems standards of reliability; evident capability of meeting system safety requirements; favorable cost/benefit tradeoff considering projected missions and technology advancement potential; and proven feasibility of fabricating and qualifying a flight system and integrating it with a candidate spacecraft and launch vehicle. As a result of considerable government investment in Brayton system component development, the MHW isotope heat source and the BIPS Phase I Ground Demonstration System, the BIPS is a more advanced state of development than any previous radioisotope power system technology. Evidence of this is presented along with a complete review of the attributes, the contractor recommended ratings, and the rationale for the self-evaluation.

  15. Evaluation of four volume-based image registration algorithms.

    Science.gov (United States)

    Zhang, Yunkai; Chu, James C H; Hsi, Wenchien; Khan, Atif J; Mehta, Parthiv S; Bernard, Damian B; Abrams, Ross A

    2009-01-01

    We evaluated 4 volume-based automatic image registration algorithms from 2 commercially available treatment planning systems (Philips Syntegra and BrainScan). The algorithms based on cross correlation (CC), local correlation (LC), normalized mutual information (NMI), and BrainScan mutual information (BSMI) were evaluated with: (1) the synthetic computed tomography (CT) images, (2) the CT and magnetic resonance (MR) phantom images, and (3) the CT and MR head image pairs from 12 patients with brain tumors. For the synthetic images, the registration results were compared with known transformation parameters, and all algorithms achieved accuracy of submillimeter in translation and subdegree in rotation. For the phantom images, the registration results were compared with those provided by frame and marker-based manual registration. For the patient images, the results were compared with anatomical landmark-based manual registration to qualitatively determine how the results were close to a clinically acceptable registration. NMI and LC outperformed CC and BSMI, with the sense of being closer to a clinically acceptable result. As for the robustness, NMI and BSMI outperformed CC and LC. A guideline of image registration in our institution was given, and final visual assessment is necessary to guarantee reasonable results.

  16. SSI`s International Development Co-operation (SIUS). Annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    Szendroe, G.; Grapengiesser, S.; Johansson, Gunnar

    1999-04-01

    SSI`s International Development Co-operation (SIUS), the Swedish program for radiation protection work in Central and Eastern Europe, has since its start in 1992 been granted SEK 109 million by the Swedish government. The projects are accessed, planned and performed in close co-operation with partner organisations in Eastern Europe. This report presents the financial status and a summary of the projects, their status and distribution over the countries and project areas. The presentation is updated as of December 1998

  17. Cross-border Co-operation and Policy Networks in West Africa

    DEFF Research Database (Denmark)

    Trémolières, Marie; Walther, Olivier

    This publication examines how policy actors involved in cross-border co-operation contribute to the regional integration process in West Africa. It uses a pioneering methodology, known as social network analysis, to visualise the formal and informal relationships between actors involved in cross......-border policy networks, showing that borders have notable and diverse impacts on exchanges of information and the relative power of networks. The report then analyses a range of regional indicators of co-operation potential, visually demonstrating that borders can also affect the ability of sub-regions within...

  18. DAIRY CO-OPERATIVES AND MILK MARKETING IN INDIA: CONSTRAINTS AND OPPORTUNITIES

    OpenAIRE

    Rajendran, K; Mohanty, Samarendu

    2004-01-01

    Operation Flood and dairy co-operatives emerged in India as the largest rural employment scheme, enabling the modernization of the dairy sector to a level from where it can take off to meet not only the country'Â’s demand for milk and milk products but can also exploit global market opportunities. This study reviews the existing status of milk marketing and dairy co-operatives in India and provides recommendations to meet future challenges. The results of the study indicate that 80 percent of...

  19. Hydrocarbonization process evaluation report. Volume II. Evaluation of process feasibility. [49 refs

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, J.M.; Dyslin, D.A.; Edwards, M.S.; Joy, D.S.; Peterson, G.R.

    1977-07-01

    Volume II of a two-volume study concerning the preliminary design and economic evaluation of a Hydrocarbonization Facility includes: (1) a review of the current status of the major processing units, (2) an assessment of operating problems, (3) considerations of possible process alternatives, (4) an evaluation of the overall process feasibility, and (5) recommendations for future process development. Results of the study emphasize the need for testing the evaluated process, which is based on the Clean Coke Process, in a continuous pilot plant using a wide variety of highly caking bituminous coals as feed material. A program suggested for the pilot plant would encompass: (1) development of improved methods for the prevention of agglomeration of highly caking coals during hydrocarbonization, (2) optimization of the yields of coal liquids, (3) investigation of a single-stage high-temperature hydrocarbonizer optimized for char production, and (4) optimization of beneficiation ratios employed during coal preparation.

  20. Japan-Australia Co-operative Program on research and development of technology for the management of high level radioactive wastes: phase II (1990-1995)

    Energy Technology Data Exchange (ETDEWEB)

    Banba, Tsunetaka [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Hart, K.P. [eds.

    1996-05-01

    The major activities associated with Japan-Australia Co-operative Program were the preparation, characterization and subsequent testing of both Cm-doped Synroc containing PW-4b simulated waste and Cm-doped single-phase zirconolite and perovskite, and the initiation of studies on naturally-occurring zirconolites to study the long-term durability of this mineral phase over geological time. The preparation of the Cm-doped samples was carried out in JAERI`s WASTEF facility at Tokai, with technical information and assistance provided by ANSTO where necessary. The experiments were designed to induce accelerated radiation damage in Synroc samples that would correspond to periods of Synroc storage of up to 100,000 years. The results are of considerable importance in evaluating the potential of the Synroc process as a means of dealing with HLW waste streams and represent a significant contribution to the understanding of the ability of Synroc to immobilize HLW elements. Overall the Phase II Co-operative Program has continued the excellent co-operative working relationship between the staff at the two institutions, and provided a better understanding of the potential advantages and limitations of Synroc as a second generation waste form. The work has shown the need for additional studies to be carried out on the effect of the levels of Cm-doping on the Cm leach rate, extension of natural analogue studies to define the geological conditions under which zirconolite is stable and development of models to provide long-term predictions of releases of HLW elements from Synroc under a range of repository conditions. It is strongly recommended that the program carried out in Phase II of the Co-operative Agreement be extended for a further three years to allow additional information on the above areas to be collected and reported in a document providing an overview of the Co-operative Program and recommendations on HLW management strategies. (J.P.N.).

  1. Science, technology and institutional co-operation in Africa: from pre ...

    African Journals Online (AJOL)

    This paper covers two phases of the history of science, technology and institutional co-operation in Africa - pre-colonial and colonial. It is structured into three sections. Section one looks at pre-colonial science and technology (S&T) and points out that most discussions on the socioeconomic analysis of S&T in Africa often ...

  2. Members' Preferences for Co-operative Structures: An Experimental Conjoint Study

    NARCIS (Netherlands)

    Kalogeras, N.; Lans, van der I.A.; Pennings, J.M.E.; Dijk, van G.

    2004-01-01

    Abstract As market conditions change rapidly in the 21st century, questions arise concerning how the organizational structures of co-operatives (co-ops) can meet the challenges that these new conditions pose. This paper introduces a framework to structure marketing co-ops (MCs) based on members¿

  3. Some "Get It" More than Others: Cultivating a Co-Operative Ethos in Uncertain Times

    Science.gov (United States)

    Davidge, Gail

    2013-01-01

    This article seeks to explore the dilemmas that schools and their members encounter whilst striving to establish a co-operative culture within an educational landscape contoured by decades of neo-liberal policy "reform". In order to (re)consider the construction of democratic subjectivity within contemporary educational discourse, the…

  4. Are University Co-Operative Education Students Safe? Perceptions of Risk to Students on Work Terms

    Science.gov (United States)

    Newhook, Rebecca

    2016-01-01

    As students venture off campus for university-sponsored activities, are they at risk, given that universities are better able to control risk factors on campus than they can for their off-campus activities? Co-operative education is a formalized and longstanding academic program that often sees students spend upwards of a third of their time off…

  5. Effect of co-operative fuzzy c-means clustering on estimates of three ...

    Indian Academy of Sciences (India)

    We determine the degree of variation of model fitness,to a true model based on amplitude variation with angle (AVA)methodology for a synthetic gas hydrate model,using co-operative fuzzy c-means clustering,constrained to a rock physics model.When a homogeneous starting model is used,with only traditional least ...

  6. A novel model for extending international co-operation in science and education

    NARCIS (Netherlands)

    de Boer, S.J.; Ji-zehn, Q.

    2004-01-01

    Journal of Zhejiang University SCIENCE (ISSN 1009-3095, Monthly) 2004 Vol. 5 No. 3 p.358-364 --------------------------------------------------------------------------------A novel model for extending international co-operation in science and educationDE BOER Sirp J.1, QIU Ji-zhen 2(1International

  7. [SUPPORT, CO-OPERATIVE EDUCATION PROGRAMMES, PRAGMATIC CODE OF ETHICS: A CLINICAL APPROACH OF EXECUTIVE TRAINING].

    Science.gov (United States)

    Cabaret, Véronique

    2016-01-01

    This article aims at introducing an educational sequence completed at l'Institut de Formation des Cadres de Santé (IFCS) at the CHRU in Lille in France, entitled "training project and educational project" present in the "training duties" module whose goal is to generate students'knowledge through co-operative education programmes. By creating this innovative sequence, the educational aim is to use the Institut ground as a ground of learning, associated with the various internship grounds, in order to get the most of co-operative education programmes. Besides, in a pragmatic code of ethics in training, the teaching staff draw their inspiration from a clinical approach of executive training: they regard students as true protagonists in a co-operative plan created for them, wishing to design it with them using their words. Thus, students are brought to criticize the IFCS educational project and debate it with the trainers who have built it. Each partner tries to understand the Other, being aware of their being different. By contributing every year to rewriting the educational project which directly concerns them, students build their professional positions as health executives. They play an active role in co-operative education programmes just like IFCS outside partners.

  8. Financial Instruments and Conflicts of Interest: Application to French Agricultural Co-operatives

    Directory of Open Access Journals (Sweden)

    Francis Declerck

    2015-11-01

    Agricultural co-operatives' governance and economic projects are often misunderstood by external financial investors. The risk of conflicts of interest plays a role in these misunderstandings in the way retained earnings, returns to agricultural products brought by co-op member and returns to equity capital. Such risks are identified and answers are proposed.

  9. Using Peer Teaching to Support Co-Operative Learning in Undergraduate Pharmacology

    Science.gov (United States)

    Depaz, Iris; Moni, Roger W.

    2008-01-01

    We report findings from the second phase of a study of co-operative, group-based assessment in Pharmacology for second-year undergraduates at The University of Queensland, Australia. Students (n = 285) enrolled in the 2006 Bachelor of Science degree program completed a group-based assessment task (weighted 10% of their course). Blended teaching…

  10. Microcredit management in Ghana : development of co-operative credit unions among the Dagaaba

    NARCIS (Netherlands)

    Gheneti, Yeshanew

    2007-01-01

    "This thesis focuses on the historical development, the organizational management and the role of credit unions among the Dagaaba in the Upper West Region of Ghana. Co-operative credit unions are well-established financial institutions, with a capacity to mobilize local savings and provide

  11. Potentials For The Development Of Co-Operatives In The Nigerian ...

    African Journals Online (AJOL)

    Co-operatives are important in the socio-economic development of nations. Basically, they strive to achieve individual and collective self – reliance, activation of indigenous human and material resources, equal opportunities, democracy, solidarity, improved standard of living for members, access to capital, increased ...

  12. Performance of agricultural co-operative societies in Mubi zone of ...

    African Journals Online (AJOL)

    This study examined the performance of agricultural co-operative societies (ACS) in Mubi zone of Adamawa State of Nigeria. The objectives of the study were to: Identify and describe the socio-economic characteristics of agricultural cooperative societies, determine the impact of ACS credit on the participating former's ...

  13. The Organisation for Economic Co-Operation and Development's International Early Learning Study: What Happened Next

    Science.gov (United States)

    Moss, Peter; Urban, Mathias

    2017-01-01

    In this article, the authors provide an update on what has happened over recent months with the Organisation for Economic Co-operation and Development's proposal for an International Early Learning Study, and review responses to the proposed International Early Learning Study, including the concerns that have been raised about this new venture in…

  14. Understanding mechanisms of enzyme co-operativity: The importance of not being at equilibrium

    Directory of Open Access Journals (Sweden)

    María Luz Cárdenas

    2015-03-01

    Full Text Available The discovery at the end of the 1950s and the beginning of the 1960s that there were enzymes like threonine deaminase and aspartate transcarbamoylase that failed to follow the expected hyperbolic behaviour predicted by the Michaelis–Menten equation, raised several questions and induced the development of mechanisms to explain this peculiar behaviour. At that time it was already known that the binding of oxygen to haemoglobin did not follow a hyperbolic curve, but a sigmoidal one, and it was thought that a similar situation probably existed for enzymes with sigmoidal kinetics. In other words, the observed kinetic behaviour was a consequence of co-operativity in the substrate binding. Two main models were postulated: those of Monod, Wyman and Changeux in 1965 and of Koshland, Némethy and Filmer in 1966. Both consider that the different conformations are in equilibrium and that there is a rapid equilibrium in the binding, which implies that co-operativity could only exist if there is more than one substrate binding site per enzyme molecule, that is, if the enzyme is an oligomer. What about monomeric enzymes, could they show kinetic co-operativity? Yes, but only through mechanisms that imply the existence of enzyme conformations that are not in equilibrium, and have different kinetic parameters. There are, in fact, very few examples of monomeric enzymes showing kinetic co-operativity with a natural substrate. The case of “glucokinase” (hexokinase D or hexokinase IV, a monomeric enzyme with co-operativity with respect to glucose, will be discussed.

  15. Evaluation of Occupant Volume Strength in Conventional Passenger Railroad Equipment

    Science.gov (United States)

    2008-09-24

    To ensure a level of occupant volume protection, passenger : railway equipment operating on mainline railroads in the : United States must be designed to resist an 800,000-lb : compressive load applied statically along the line of draft. An : alterna...

  16. Power corrupts co-operation: cognitive and motivational effects in a double EEG paradigm.

    Science.gov (United States)

    Kanso, Riam; Hewstone, Miles; Hawkins, Erin; Waszczuk, Monika; Nobre, Anna Christina

    2014-02-01

    This study investigated the effect of interpersonal power on co-operative performance. We used a paired electro-encephalogram paradigm: pairs of participants performed an attention task, followed by feedback indicating monetary loss or gain on every trial. Participants were randomly allocated to the power-holder, subordinate or neutral group by creating different levels of control over how a joint monetary reward would be allocated. We found that power was associated with reduced behavioural accuracy. Event-related potential analysis showed that power-holders devoted less motivational resources to their targets than did subordinates or neutrals, but did not differ at the level of early conflict detection. Their feedback potential results showed a greater expectation of rewards but reduced subjective magnitude attributed to losses. Subordinates, on the other hand, were asymmetrically sensitive to power-holders' targets. They expected fewer rewards, but attributed greater significance to losses. Our study shows that power corrupts balanced co-operation with subordinates.

  17. NATO, Libya operations and intelligence co-operation – a step forward?

    DEFF Research Database (Denmark)

    Svendsen, Adam David Morgan

    2011-01-01

    "With the ‘fall’ of Tripoli towards the end of August 2011, it has become increasingly apparent that the intelligence co-operation witnessed in Libya during the NATO campaign performed an increasingly important role in realizing operational and strategic ‘successes’. These recent intelligence...... developments can be opened up for some further analysis, forming the main focus of this article. Ultimately, this article concludes that, over time and albeit while gradual, we have seen what can be regarded as ‘a step forward’ in co-operative intelligence activities in Libya. Although several pressing...... difficulties have been present, and have had various impacts at different junctures of interactivity, the ‘problems’ encountered have not completely overwhelmed either operationally or strategically all of the diverse participants involved in Libya." - Abstract from journal....

  18. Some like to join, others to deliver. An econometric analysis of farmers’ relationships with agricultural co-operatives

    NARCIS (Netherlands)

    Gardebroek, C.; Pascucci, S.

    2010-01-01

    In many European countries, farmers are a member of a processing or marketing co-operative, and most of these farmers also deliver their products to that co-operative. However, an extensive dataset of Italian farmers shows that not all members deliver to their co-op, and that there are also

  19. Experiences in Regional Cross Border Co-operation in River Management. Comparing Three Cases at the Dutch–German Border

    NARCIS (Netherlands)

    Wiering, M.A.; Verwijmeren, J.A.; Lulofs, K.; Feld, C.

    2010-01-01

    Cross border co-operation is increasingly viewed as an obvious and logical consequence of an integrated perspective on river management. Consequently, we would expect an increase of cross border co-operation and collaboration in EU member states, through joint planning, co-management or

  20. Socialité et co-operation dans l'oeuvre de Charles Goodwin

    DEFF Research Database (Denmark)

    Mondeme, Chloé

    2016-01-01

    As a linguistic anthropologist, Goodwin elaborates a conceptual and methodological framework to describe the organization of human activities and conducts. The central notion of « co-operation » accounts for what is at stake in ordinary conversation as well as in professional practices, cultural ...... on the tools and concepts that have progressively emerged, and will eventually evoke the potential payoffs of such a body of work for the French social sciences....

  1. Co-operation of digital nonlinear equalizers and soft-decision LDPC FEC in nonlinear transmission.

    Science.gov (United States)

    Tanimura, Takahito; Oda, Shoichiro; Hoshida, Takeshi; Aoki, Yasuhiko; Tao, Zhenning; Rasmussen, Jens C

    2013-12-30

    We experimentally and numerically investigated the characteristics of 128 Gb/s dual polarization - quadrature phase shift keying signals received with two types of nonlinear equalizers (NLEs) followed by soft-decision (SD) low-density parity-check (LDPC) forward error correction (FEC). Successful co-operation among SD-FEC and NLEs over various nonlinear transmissions were demonstrated by optimization of parameters for NLEs.

  2. Evolution of Co-operation When the Strategies are Hidden: The Human Mating Game

    OpenAIRE

    Milind Watve; Anuja Damle; Bratati Ganguly; Anagha Kale

    2007-01-01

    Defection is frequently seen in co-operative systems [1-3]. Game theoretical solutions to stabilize cooperation rely on reciprocity and reputation in iterated games[4-5]. One of the basic requirements for reciprocity or reputation building is that the strategies of players and the resulting payoffs should be open at the end of every interaction. For games in which the strategies and payoffs remain hidden, these stabilizing factors are unlikely to work. We examine the evolution of cooperation ...

  3. Prospects of Economic Co-operation of Ukraine and Middle East Countries

    OpenAIRE

    Omar Ismael Omar

    2013-01-01

    The article sets prospects of interaction of Ukrainian economy with Middle East economies on the basis of analysis of state of qualitative and quantitative parameters of economic and humanitarian relations. It proves that the following is required for fast improvement of the situation: substantial and closer co-operation of Middle East regions with foreign economic relations departments of Ukraine; expert study of prospects and possibilities of promotion of Ukrainian regions in Middle East ma...

  4. Evaluation of right ventricular volumes measured by magnetic resonance imaging

    DEFF Research Database (Denmark)

    Møgelvang, J; Stubgaard, M; Thomsen, C

    1988-01-01

    Right ventricular volumes were determined in 12 patients with different levels of right and left ventricular function by magnetic resonance imaging (MRI) using an ECG gated multisection technique in planes perpendicular to the diastolic position of the interventricular septum. Right ventricular...

  5. Evaluation of left ventricular volumes measured by magnetic resonance imaging

    DEFF Research Database (Denmark)

    Møgelvang, J; Thomsen, C; Mehlsen, J

    1986-01-01

    Left ventricular end-diastolic and end-systolic volumes were determined in 17 patients with different levels of left ventricular function by magnetic resonance imaging (MRI). A 1.5 Tesla Magnet was used obtaining ECG triggered single and multiple slices. Calculated cardiac outputs were compared...

  6. Letter to editor Platelet volume evaluation in patients with sepsis ...

    African Journals Online (AJOL)

    I have read the article published by Guclu et al. with a great interest.1 They examined platelet indices in patients with sepsis. Mean platelet volume (MPV) and platelet distribution width (PDW) were significantly higher in patients with sepsis than in controls. MPV and PDW were significantly higher in patients with severe ...

  7. Strengthening the Radiation Protection System in Cuba (SRPS - Cuba). A co-operation project between Cuban and Swedish institutions, February 2001 - June 2003

    Energy Technology Data Exchange (ETDEWEB)

    Avila, Rodolfo; Larsson, Carl-Magnus; Prendes, Miguel; Zerquera, Juan Tomas

    2004-02-01

    This project results from the co-operation between a number of Cuban and Swedish institutions. It started in February 2001 and ended in June 2003 and was made possible thanks to the contributions of the Swedish International Development Co-operation Agency (SIDA), the Centro de Proteccion e Higiene de las Radiaciones, Cuba (CPHR), and the Swedish Radiation Protection Authority (SSI). The overall objective was to strengthen the radiation protection system in Cuba, and in this way contribute with the control and reduction of risks to man and the environment from exposures to ionizing radiation. The project focused on four priority areas: 1) Protection of workers and patients exposed to radiation in radiation practices; 2) Preparedness for response to an emergency situation; 3) Environmental radiological protection; and, 4) Exposure to radiation in areas with high levels of natural radioactivity. The present report summarizes the findings of the whole project period, providing an overview of the overall achievements, as well as listing its deliverables. The results of an evaluation of the project, conducted during the final workshop, are also included. The report ends with a list of generic and specific conclusions and recommendations for implementation of the project's achievements and for further development of co-operation.

  8. Industrial process heat data analysis and evaluation. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Lewandowski, A; Gee, R; May, K

    1984-07-01

    The Solar Energy Research Institute (SERI) has modeled seven of the Department of Energy (DOE) sponsored solar Industrial Process Heat (IPH) field experiments and has generated thermal performance predictions for each project. Additionally, these performance predictions have been compared with actual performance measurements taken at the projects. Predictions were generated using SOLIPH, an hour-by-hour computer code with the capability for modeling many types of solar IPH components and system configurations. Comparisons of reported and predicted performance resulted in good agreement when the field test reliability and availability was high. Volume I contains the main body of the work; objective model description, site configurations, model results, data comparisons, and summary. Volume II contains complete performance prediction results (tabular and graphic output) and computer program listings.

  9. An Evaluation of the Nutrition Services for the Elderly. Volume II. Analytic Report.

    Science.gov (United States)

    Kirschner Associates, Inc., Albuquerque, NM.

    This document is part of a five-volume nationwide study of Nutrition Service operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. This volume contains the analytic report, which presents the major findings of the evaluation. Chapter 1 gives a report…

  10. Celebrating Co-operation among Saskatchewan’s Libraries: The Multitype Library Board, 1996-2016

    Directory of Open Access Journals (Sweden)

    Michael Shires

    2016-03-01

    Full Text Available Saskatchewan’s Multitype Library Board (MLB celebrates its 20th anniversary in 2016. It was established under the passage of the provincial government’s The Libraries Co- operation Act in 1996 to facilitate the co-operative development of the multitype library system in Saskatchewan. This legislation is unique in Canada. The MLB is a Minister of Education Advisory Board and it provides a forum to promote and facilitate co-operation among over 320 public libraries in 10 provincial systems, 25 post-secondary libraries, 755 school libraries, several special libraries, and other information providers. Major milestones of the MLB include helping to eliminate the Provincial Sales Tax on library subscriptions, establishing a provincial digitization plan, and creating a cross-sector database licensing program that has resulted in a projected value of 14.8 million dollars to Saskatchewan users in 2014. The development of the MLB and the impact of the programs it has initiated will be discussed, and recommendations for developing a collaborative initiative will be provided. Le Multitype Library Board (MLB de Saskatchewan fête son 20e anniversaire en 2016. Il était établi sous l’Acte The Libraries Co-operation du parti Libéral en 1996 pour faciliter le développement coopératif du système de bibliothèque Multitype en Saskatchewan. Cette législation est unique au Canada. Le MLB est un comité consultatif du ministère de l’Éducation et il fournit un forum pour promouvoir et faciliter la coopération entre plus de 320 bibliothèques publiques dans dix systèmes provinciaux, 25 bibliothèques postsecondaires, 755 bibliothèques scolaires, plusieurs bibliothèques spéciales, et d’autres fournisseurs d’informations. Les étapes importantes du MLB comprennent, à aider à éliminer les taxes de vente provinciale sur les abonnements aux bibliothèques, à établir un plan provincial de numérisation, et à créer un programme de licence

  11. Clinical leadership: evaluating the benefits of action learning using co-operative inquiry

    OpenAIRE

    Rosser, Elizabeth; Reeve, J.; Neale, D.; C. Smith; Valentine, J; Grey, R

    2016-01-01

    Background: Developing clinical leadership, to ensure the culture of care is strengthened, is the thrust of the ‘leading with compassion’ campaign by the English National Health Service (NHS) (NHS England, 2014). Senior clinicians are charged with invigorating compassionate leadership yet the roles of nurse and therapist consultants the most senior clinical role in the UK healthcare system, are often solitary ones, in which they are expected to embrace a myriad of responsibilities and where t...

  12. Co-operatives as a development mechanism to support job creation and sustainable waste management in South Africa

    CSIR Research Space (South Africa)

    Godfrey, Linda K

    2017-06-01

    Full Text Available great sustainability challenge. However, the waste sector can provide significant opportunities for improving livelihoods, generating jobs and developing enterprises, through the recovery of valuable recyclables. Co-operatives are recognised as a means...

  13. Evaluation of the intelligent cruise control system. Volume 2, Appendices

    Science.gov (United States)

    1999-10-01

    The Intelligent Cruise Control (ICC) system evaluation was sponsored by the National Highway Traffic Safety Administration (NHTSA) and based on an ICC Field Operational Test (FOT) conducted under a cooperative agreement between the NHTSA and the Univ...

  14. Military Training and Education: an Opportunity for V4 Co-Operation

    Directory of Open Access Journals (Sweden)

    Milan ŠUPLATA

    2015-03-01

    Full Text Available The Visegrad Group needs success stories if its defence co-operation is to develop. The recent differences between Poland and the rest of the region, as well as the closing window of opportunity to improve interoperability through the ISAF mission, make the hunger for concrete examples of co-operation even more urgent. Education and training projects are not only comparatively easily to implement in terms of time and money, but also represent a way of bringing the region’s civilian and military leaders closer together in terms of strategic thinking. Regional defence collaboration is also one of the ways to materialize NATO’s Smart Defence agenda. For the whole region, the way to keep Visegrad defence cooperation alive is not straightforward and certain, but it is likely to prove rewarding in the long term. It presents not only a chance to keep the whole region better prepared militarily, but also to build a more cohesive strategic awareness, thanks to intensive communication at all levels.

  15. Evaluation of rapid volume changes of substrate-adherent cells by conventional microscopy 3D imaging.

    Science.gov (United States)

    Boudreault, F; Grygorczyk, R

    2004-09-01

    Precise measurement of rapid volume changes of substrate-adherent cells is essential to understand many aspects of cell physiology, yet techniques to evaluate volume changes with sufficient precision and high temporal resolution are limited. Here, we describe a novel imaging method that surveys the rapid morphology modifications of living, substrate-adherent cells based on phase-contrast, digital video microscopy. Cells grown on a glass substrate are mounted in a custom-designed, side-viewing chamber and subjected to hypotonic swelling. Side-view images of the rapidly swelling cell, and at the end of the assay, an image of the same cell viewed from a perpendicular direction through the substrate, are acquired. Based on these images, off-line reconstruction of 3D cell morphology is performed, which precisely measures cell volume, height and surface at different points during cell volume changes. Volume evaluations are comparable to those obtained by confocal laser scanning microscopy (DeltaVolume microscopy without the need for cell staining or intense illumination to monitor cell volume make this system a promising new tool to investigate the fundamentals of cell volume physiology.

  16. Maritime Co-operation among South Atlantic Countries and Repercussions for the Regional Community of Security Practice

    Directory of Open Access Journals (Sweden)

    Sabrina Evangelista Medeiros

    Full Text Available Abstract This paper aims to examine the importance of co-operation for maritime security in the South Atlantic, focusing on the relationship between the national and sub-regional institutions that have leveraged this process, especially those from Brazil. For this purpose, the diagnosis addresses the debates around the contemporary roles of the navy and the importance of international co-operation for its mission accomplishment, highlighting the tasks judged as subsidiary, among them being that of maritime traffic control. The alignment of these co-operative activities with foreign policy and national defence projects can be seen through the navy’s participation in multilateral co-operation projects involving South America, particularly the Co-ordination for the South Atlantic Maritime Area (CAMAS. The research detects the existence of a particular model of a community of security practice in which national and sub-regional institutions have been generating an important maritime co-operative system, which is more stable than in other areas of co-operation in the same region.

  17. Sigmoid Colon Elongation Evaluation by Volume Rendering Technique

    Directory of Open Access Journals (Sweden)

    Atilla SENAYLI

    2011-06-01

    Full Text Available Sigmoid colons have various measurements, shapes, and configurations for individuals. In this subject there are rare clinical trials to answer the question of sigmoidal colon maldevelopment predicting a risk for volvulus. Therefore, sigmoid colon measurement may be beneficial to decide for volvulus. In a study, sigmoid colon diameters were evaluated during abdominal surgeries and it was found that median length was 47 cm and median vertical mesocolon length was 13 cm. We report a 14-year-old female patient who has a sigmoidal colon measured as nearly 54 cm. We used tomographic equipments for this evaluation. We know that MRI technique was used for this purpose but, there has not been data for MRI predicting the sigmoidal volvulus. We hope that our findings by this evaluation can contribute to insufficient literature of sigmoidal elongation. [J Contemp Med 2011; 1(2.000: 71-73

  18. An evaluation of the volume and concentration of alcoholic ...

    African Journals Online (AJOL)

    Background: One of the strategies for tackling alcoholrelated problem is education and persuasion on how to drink alcohol in moderation. This is often facilitated by the introduction of a standard alcoholic drink measure, and a recommended daily alcohol consumption limit. The objective of this study was to evaluate the ...

  19. International co-operative programme on effects on materials, including historic and cultural monuments. Environmental data report - September 1993 to August 1994

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, J.F.; Arnesen, K.; Rode, A.

    1996-04-01

    The International Co-operative Programme on Effects on Materials, including Historic and Cultural Monuments has an extensive programme on material exposure in well defined environments. This report includes the environmental data from the seventh exposure year of temperature, relative humidity, time of wetness, sunshine hours, concentrations of SO{sub 2}, NO{sub 2}, O{sub 3}, and precipitation amount and quality. The yearly results from the previous years are also reported, and the data has been evaluated in respect to internal consistency. 6 refs., 4 figs., 2 tabs.

  20. Nondestructive Evaluation of Airport Pavements. Volume I. Program References,

    Science.gov (United States)

    1979-09-01

    layer analysis. The E-value of subgrade support is assumed to be 1500(CBR) which is based on the cor- relation developed by Foster- Heukelom in 1960...Foster- Heukelom . For the purpose of discussion, if the diameter of CBR load piston is used in the Boussinesq equation, the theoretical conversion factor... Heukelom , W. and Foster, C. R., Dynamic Testing of Pavements, ASCE Trans., Vol. 127, pp.425-457, 1962. 4. Crawford, J. E., Hopkins, J. S. and Smith

  1. Evaluation of volume and solitary bone cyst remodeling using conventional radiological examination

    Energy Technology Data Exchange (ETDEWEB)

    Glowacki, Maciej; Melzer, Piotr [Karol Marcinkowski University of Medical Sciences, Department of Paediatric Orthopaedics, Poznan (Poland); Ignys-O' Byrne, Anna [J. Strus City Hospital, Department of Radiology, Poznan (Poland); Ignys, Iwona [Karol Marcinkowski University of Medical Sciences, Department of Paediatric Gastroenterology and Metabolic Diseases, Poznan (Poland); Mankowski, Przemyslaw [Karol Marcinkowski University of Medical Sciences, Department of Paediatric Surgery, Traumatology and Urology, Poznan (Poland)

    2010-03-15

    To evaluate cyst remodeling, including complete healing and recurrence, and its relation to the cyst volume in two groups of patients, using curettage and bone grafting or methylprednisolone injection. A retrospective analysis was carried out on data from 132 patients with solitary bone cyst, where 79 (59.9%) had undergone curettage and bone grafting and 53 (40.1%) had been administered methylprednisolone injection, with a mean time to follow up of 12 years. The cyst volume was evaluated from conventional radiographs and the method originally reported by Goebel et al. to evaluate the volume of Ewing's sarcoma. The results were analyzed using the criteria of Neer et al. and Capanna et al. The mean cyst volume was 36.8 cm{sup 3}. Recurrence was noted in 16 (20.2%) patients treated with curettage and in nine (17.0%) treated with methylprednisolone. Cyst volume in patients treated with curettage and bone grafting ranged from 8.3 cm{sup 3} to 100.0 cm{sup 3} and with methylprednisolone from 14.0 cm{sup 3} to 50.6 cm{sup 3}. In neither group was the cyst volume related to recurrence. Volumes from 1.3 cm{sup 3} to 81.9 cm{sup 3} were stated for patients treated with curettage and bone grafting, when complete healing was observed; they were significantly lower than for those of the total group of patients who underwent curettage and bone grafting. 1. An association between solitary cyst volume and recurrence in patients treated with either bone curettage and grafting or methylprednisolone was not found. 2. The frequency of complete healing in patients treated with bone curettage and grafting decreased with an increase in the cyst volume. (orig.)

  2. Evaluation of a simple method for determining muscle volume in vivo.

    Science.gov (United States)

    Infantolino, Benjamin W; Challis, John H

    2016-06-14

    The quantification in vivo of muscle volume is important, for example, to understand how muscles change with aging, and respond to rehabilitation. Albracht et al. (2008) suggested that muscle volume can be estimated in vivo from the measurement of muscle cross-sectional area and muscle belly length only. The purpose of this study was to evaluate this proposed relationship for determining muscle volume for both the Vastus Lateralis (VL) and First Dorsal Interosseous (FDI) using ultrasound imaging. The cross-sectional area and length of 22 cadaver FDI and 6 VL muscles in cadavers were imaged using ultrasound, these muscles were then dissected and muscle volumes measured directly using the water displacement technique. Estimated muscle volumes were compared with their direct measurement, and for the VL the percentage root mean square error in the estimation of muscle volume was 5.0%, and the Bland-Altman analysis had all volume estimates within the 95% confidence interval, with no evidence of bias (proportional or constant) in the volume estimates. In contrast, percentage root mean square error for the FDI was 18.8%, with the Bland-Altman analysis showing volume estimates outside of the 95% confidence interval and proportional bias. These results indicate that the simple method proposed by Albracht et al. (2008) for the estimation of muscle volume is appropriate the VL but not the FDI using ultrasound imaging. Morphological disparities likely account for these differences, if accurate and fast measures of the volume of the FDI are required other approaches should be explored. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Energy Extension Service Pilot Program: evaluation report after two years. Volume I. Evaluation summary

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-04-01

    The EES pilot program was initiated in August 1977, when 10 states were selected on a competitive basis for participation. The pilot states (Alabama, Connecticut, Michigan, New Mexico, Pennsylvania, Tennessee, Texas, Washington, Wisconsin, and Wyoming) devoted the first 6 months to start-up activities. This document is a follow-up report to the three volume Evaluation Summary of the first year of the pilot EES program published in September 1979. The purpose of this report is to provide an overview of the impacts and costs of the two years of the pilot program, and to check the consistency of findings over the two year period. The analysis addresses the following: (1) were the impact findings of Year I and Year II consistent, or did Year I and Year II attitudes and behavior vary. If variation existed, could it be attributed to program changes as the EES progressed from a start-up phase (Year I) to more normal service delivery (Year II); and (2) did costs of service delivery change (again reflecting start-up and normal service delivery costs). Did cost changes affect conclusions about the relative cost effectiveness of delivering services to different target audiences.

  4. Mexico City Air Quality Research Initiative; Volume 5, Strategic evaluation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Members of the Task HI (Strategic Evaluation) team were responsible for the development of a methodology to evaluate policies designed to alleviate air pollution in Mexico City. This methodology utilizes information from various reports that examined ways to reduce pollutant emissions, results from models that calculate the improvement in air quality due to a reduction in pollutant emissions, and the opinions of experts as to the requirements and trade-offs that are involved in developing a program to address the air pollution problem in Mexico City. The methodology combines these data to produce comparisons between different approaches to improving Mexico City`s air quality. These comparisons take into account not only objective factors such as the air quality improvement or cost of the different approaches, but also subjective factors such as public acceptance or political attractiveness of the different approaches. The end result of the process is a ranking of the different approaches and, more importantly, the process provides insights into the implications of implementing a particular approach or policy.

  5. Local climate activities in co-operation between municipality, civil society and science shop

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard

    involvement in projects it was proposed to involve the local branch of the environmental NGO. The starting point was topics developed by the administration and the NGO together and announced to students as part of the Science Shop project supply. The focus is climate impact of local activities and strategies...... are initiated and co-ordinated by a group with members from municipal administration, the local NGO and the Science Shop. All projects have involved student projects, but most projects have also contributed to ongoing research activities. The projects up till now have focused on the municipal food supply...... society has taken place in some projects. Results have been published locally and some nationally. Especially the food projects have got national interest. Co-operation about environmental impacts of municipal investments may be an up-coming activity....

  6. Co-Operative Coevolutionary Neural Networks for Mining Functional Association Rules.

    Science.gov (United States)

    Wang, Bing; Merrick, Kathryn E; Abbass, Hussein A

    2017-06-01

    In this paper, we introduce a novel form of association rules (ARs) that do not require discretization of continuous variables or the use of intervals in either sides of the rule. This rule form captures nonlinear relationships among variables, and provides an alternative pattern representation for mining essential relations hidden in a given data set. We refer to the new rule form as a functional AR (FAR). A new neural network-based, co-operative, coevolutionary algorithm is presented for FAR mining. The algorithm is applied to both synthetic and real-world data sets, and its performance is analyzed. The experimental results show that the proposed mining algorithm is able to discover valid and essential underlying relations in the data. Comparison experiments are also carried out with the two state-of-the-art AR mining algorithms that can handle continuous variables to demonstrate the competitive performance of the proposed method.

  7. International co-operation through the Interpol system to counter illicit drug trafficking.

    Science.gov (United States)

    Leamy, W J

    1983-01-01

    The International Criminal Police Organization (ICPO/Interpol), whose main aim is the prevention and suppression of ordinary crime, has 135 member countries. The Government of each of these countries has designated an Interpol National Central Bureau to co-operate and liaise within the framework of Interpol. The Drugs Sub-Division of Interpol's General Secretariat monitors and responds to incoming communications on drug enforcement matters, conducts intelligence analysis of information and produces tactical and strategic intelligence reports as well as statistical and other specialized reports. It received 33,181 and dispatched 6,741 drug-enforcement-related communications in 1982, which was over 60 per cent of the entire communications of the General Secretariat. The Drugs Sub-Division participates in drug training and drug strategy seminars world-wide. Interpol also carries out drug liaison officer programmes in five regions of the world.

  8. HARNESSING THE HUMAN POTENTIAL TEAMS IN CO-OPERATIVE ORGANIZATIONS IN THE LIGHT OF EUROPEAN MANAGEMENT

    Directory of Open Access Journals (Sweden)

    GRAUR Elena

    2017-06-01

    Full Text Available Human potential was and is among the most valuable resources that each organization has, and also one of the decisive resources for an efficient business activity and its evolution in performance. All management functions are performed by people while success or failure of the management activity depends on acquiring the art of working with people. When the top managers succeed to harness the potential of the employees so that they become not subordinates but teammates in the future activities of the organization, we can already speak about highly qualified professionals who generate sustainable development of the employing company. The research will mainly focus on the comparative study of approaches practiced in European countries along with co-operative enterprises from our country, researching the training level and theoretical-practical training provided by authorized institutions in these domains.

  9. Evaluation of dose according to the volume and respiratory range during SBRT in lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Deuk Hee [Dept. of Radiation Oncology, Busan Paik Hospital, Inje University, Busan (Korea, Republic of); Park, Eun Tae; Kim, Jung Hoon; Kang, Se Seik [Dept. of Radiological Science, College of Health Sciences, Catholic University of Pusan, Busan (Korea, Republic of)

    2016-09-15

    Stereotactic body radiotherapy is effective technic in radiotherapy for low stage lung cancer. But lung cancer is affected by respiratory so accurately concentrate high dose to the target is very difficult. In this study, evaluated the target volume according to how to take the image. And evaluated the dose by photoluminescence glass dosimeter according to how to contour the volume and respiratory range. As a result, evaluated the 4D CT volume was 10.4 cm{sup 3} which was closest value of real size target. And in dose case is internal target volume dose was 10.82, 16.88, 21.90 Gy when prescribed dose was 10, 15, 20 Gy and it was the highest dose. Respiratory gated radiotherapy dose was more higher than internal target volume. But it made little difference by respiratory range. Therefore, when moving cancer treatment, acquiring image by 4D CT, contouring internal target volume and respiratory gated radiotherapy technic would be the best way.

  10. Sweden's Co-operation with Eastern Europe in Radiation Safety 2011

    Energy Technology Data Exchange (ETDEWEB)

    Dassen, Lars van; Andersson, Sarmite; Bejarano, Gabriela; Chirman, Inessa; Delalic, Zlatan; Ekblad, Christer; Karlberg, Olof; Klasen, Haakan; Olsson, Kjell; Sandberg, Viviana; Stenberg, Tor; Turner, Roland; Wickman, Barbro

    2012-11-01

    In 2011, the Swedish Radiation Safety Authority implemented co-operation projects in Russia, Ukraine, Georgia, Lithuania and Moldova, based on instructions from the Swedish Government and agreements with the European Union and the Swedish International Development Co-operation Agency, SIDA. The projects aim at achieving a net contribution to radiation safety (including nuclear safety, nuclear security, waste management, nonproliferation as well as radiation protection and emergency preparedness) for the benefit of the host countries and the international community as well as Sweden. This report gives an overview of all the projects implemented in 2011. The project managers from SSM are the cornerstones of our successful work, but all the efforts and dedication by staff members of the facilities and authorities in the mentioned countries are indispensable for the long-term positive outcomes. This report is meant to serve as a detailed account regarding SSM's efforts as part of the Swedish international activities, on which Sweden will report to the Nuclear Security Summit in Seoul. The parties to the G-8 Global Partnership have in June 2011 extended the Global Partnership for ten more years, till 2022. Other international frameworks, such as the UNSC Resolution 1540, remain a vibrant instrument by which UN Member States can exchange information on security concerns and request assistance from each other. The projects that SSM implements in Moldova and Georgia have a reference to the aims and purposes of the UNSC Resolution 1540. Much work has been done in the fields of nuclear security and safety, but there are still lots of issues that need to be taken care of. As such, SSM will continue to do its part for nuclear safety and security at the international level, along the lines and priorities set by our Government.

  11. Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: a 'Big Brother' evaluation.

    NARCIS (Netherlands)

    Steenbakkers, R.J.; Duppen, J.C.; Fitton, I.; Deurloo, K.E.; Zijp, L.; Uitterhoeve, A.L.; Rodrigus, P.T.; Kramer, G.W.P.M.; Bussink, J.; Jaeger, K. de; Belderbos, J.S.; Hart, A.A.M.; Nowak, P.J.; Herk, M. van; Rasch, C.R.

    2005-01-01

    BACKGROUND AND PURPOSE: To evaluate the process of target volume delineation in lung cancer for optimization of imaging, delineation protocol and delineation software. PATIENTS AND METHODS: Eleven radiation oncologists (observers) from five different institutions delineated the Gross Tumor Volume

  12. Energy extension service pilot program evaluation report: the first year. Volume III: supplementary reports

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-09-01

    The appendices presented in this volume support and supplement Volume I of the Energy Extension Service Pilot Program Evaluation Report: The First Year. The appendices contain back-up data and detailed information on energy savings estimation and other analytic procedures. This volume also describes the data sources used for the evaluation. Appendix I presents the Btu estimation procedures used to calculate state-by-state energy savings. Appendix II contains details of the data sources used for the evaluation. Appendix III presents program activity data, budget, and cost per client analyses. Appendix IV, the Multivariate Analysis of EES Survey Data, provides the basis for the Integrating Statistical Analyses. Appendix V describes the rationale and exclusion rules for outlying data points. The final appendix presents program-by-program fuel costs and self-reported savings and investment.

  13. Evaluation of various Deformable Image Registrations for Point and Volume Variations

    CERN Document Server

    Han, Su Chul; Park, Seungwoo; Lee, Soon Sung; Jung, Haijo; Kim, Mi-Sook; Yoo, Hyung Jun; Ji, Young Hoon; Yi, Chul Young; Kim, Kum Bae

    2015-01-01

    The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference image (Iref) and volume (Vref) was first generated with virtual deformation QA software (ImSimQA, Oncology System Limited, UK). We deformed Iref with axial movement of deformation point and Vref depending on the types of deformation that are the deformation1 is to increase the Vref (relaxation) and the deformation 2 is to decrease . The deformed image (Idef) and volume (Vdef) acquired by ImSimQA software were inversely deformed to Iref and Vref using DIR algorithms. As a result, we acquired deformed image (Iid) from Idef and volume (Vid) from Vdef. The DIR algorithms were the Horn Schunk optical flow (HS), Iterative Optical Flow (IOF), Modified Demons (MD) and Fast Demons (FD) with the Deformable Image Registration and Adaptive Radiotherapy Toolkit (DIRART) of MATLAB. The imag...

  14. Social Incentive Mechanism Based Multi-User Sensing Time Optimization in Co-Operative Spectrum Sensing with Mobile Crowd Sensing.

    Science.gov (United States)

    Li, Xiaohui; Zhu, Qi

    2018-01-16

    Co-operative spectrum sensing emerging as a significant method to improve the utilization of the spectrum needs sufficient sensing users to participate. Existing related papers consider only the limited secondary users in current sensing system and assume that they will always perform the co-operative spectrum sensing out of obligation. However, this assumption is impractical in the realistic situation where the secondary users are rational and they will not join in the co-operative sensing process without a certain reward to compensate their sensing energy consumption, especially the ones who have no data transmitting in current time slot. To solve this problem, we take advantage of the mobile crowd sensing to supply adequate co-operative sensing candidates, in which the sensing users are not only the secondary users but also a crowd of widely distributed mobile users equipped with personal spectrum sensors (such as smartphones, vehicle sensors). Furthermore, a social incentive mechanism is also adapted to motivate the participations of mobile sensing users. In this paper, we model the interactions among the motivated sensing users as a co-operative game where they adjust their own sensing time strategies to maximize the co-operative sensing utility, which eventually guarantees the detection performance and prevents the global sensing cost being too high. We prove that the game based optimization problem is NP-hard and exists a unique optimal equilibrium. An improved differential evolution algorithm is proposed to solve the optimization problem. Simulation results prove the better performance in our proposed multi-user sensing time optimization model and the proposed improved differential evolution algorithm, respectively compared with the non-optimization model and the other two typical equilibrium solution algorithms.

  15. Leadership role of Consultant Nurses working with Older People: a co-operative inquiry.

    Science.gov (United States)

    Manley, Kim; Webster, Jonathan; Hale, Nick; Hayes, Nicky; Minardi, Henry

    2008-03-01

    The aim of the co-operative enquiry undertaken was to explore how the leadership component of the Consultant Nurse for Older People role was reflected in day-to-day working. Leadership is one of the four key elements of the Consultant Nurse role and is the key mechanism for achieving and embedding transformation in practice. However, within the role of the Consultant Nurse this area has not been explored in detail. A 6-month co-operative inquiry approach was used to develop insights into leadership strategies of Consultant Nurses for Older People and involved the five authors of the paper, four Consultant Nurses in Older People nursing and the lead author who was also an experienced Consultant Nurse and practice-based researcher from a different nursing specialism. Through the analysis of the stories shared by the co-authors/participants, two key themes emerged relating to complexity and pathway. These themes provided a major focus for the Consultant Nurses in their leadership role. The outcome of the study is a framework that describes the triggers and enabling factors that precede the use of leadership strategies at the clinical and organizational level and associated outcomes. In defining how leadership is reflected by Consultant Nurses for Older People, a complex picture emerges that is multifaceted and multidimensional. Consultant Nurses need support to make visible the valuable contribution they make to enabling healthcare teams, organizations and work places. Consultant Nurses for Older People are key in ensuring the quality agenda within their organizations as they are well placed to provide leadership at both a strategic and clinical level, while providing influence to operational development. Within the context of the literature this area is under investigated. Understanding how leadership is reflected in the role of Consultant Nurses is complex as Consultant Nurses work across traditional interfaces and between different levels within organizations

  16. Crossborder Co-operation as a Tool for Trans-national Integration and Conflict Resolution: The Upper Adriatic Euroregional Experiences

    OpenAIRE

    Del Bianco, Daniele

    2006-01-01

    If we portray borders as places for exchange and co-operation instead of barriers, it is straightforward to picture them as resources for re-unification and conflicts' resolution. The development of institutionalised forms of cross-border co-operation, originating from a will of populations and institutions of different states to face common problems, lead to the concept of Euroregion. The enlarged EU has been en¬couraging the creation of such forms of decentralisation of power, in the econom...

  17. Danish environmental support fund for Eastern Europe. Co-operation development 1991-1996 and programme priority areas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-08-01

    The publication gives an account of environmental co-operation between Denmark and 12 countries in Eastern Europe. The basis of co-operation is a country programme, describing present and future priority areas in the recipient countries, as an expression of common understanding between the Danish Environmental Protection Agency and the Ministry of Environment in the recipient countries. The publication also describe the environmental efforts made in 1991-1996 under the Danish Environmental Support Fund for Eastern Europe (DESF) administered by the DEPA. (au)

  18. Evaluation of graded limestone base course on a low volume road : final report.

    Science.gov (United States)

    1985-04-01

    Due to decreasing supplies of native aggregate which may be incorporated into a base course, other materials need to be evaluated for constructibility and performance. To this end, a graded limestone base was constructed on a low volume road and eval...

  19. Tamper-indicating devices and safeguards seals evaluation test report. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Horton, P.R.V.; Waddoups, I.G.

    1995-08-01

    Volume I was based on a survey and an evaluation of seals that are used as tamper-indicating devices at DOE facilities. For that evaluation, currently available seals were physically and environmentally evaluated under two broad categories: handling durability and tamper resistance. Our study indicated that the environmental testing had no negative effects on the results of the mechanical tests. In Volume II, we evaluate some loop, fiber optic loop, and pressure-sensitive seals that are not used at DOE facilities. However, we continue to focus on qualities required by DOE: durability and tamper resistance. The seals are comparatively rated, and recommendations are made for using currently available seals and new tamper-indicating device technology.

  20. Electric and Magnetic Fields (EMF) RAPID Program Engineering Project 8: FINAL REPORT, Evaluation of Field Reduction Technologies, Volume 1 (Report) and Volume 2 (Appendices)

    Energy Technology Data Exchange (ETDEWEB)

    Commonwealth Associates, Inc.; IIT Research Institute

    1997-08-01

    This draft report consists of two volumes. Volume 1, the main body, contains an introducto~ sectionj an overview of magnetic fields sectio~ and field reduction technology evaluation section. Magnetic field reduction methods are evalpated for transmission lines, distribution Iines,sulxtations, building wiring applkmd machinery, and transportation systems. The evaluation considers effectiveness, co% and other ftiors. Volume 2 contains five appendices, Append~ A presents magnetic field shielding information. Appendices B and C present design assumptions and magnetic field plots for transmission and distribution lines, respectively. Appendices D and E present cost estimate details for transmission and distribution limes, respectively.

  1. Simple and efficient technique for evaluating the optical losses from surface scattering and volume attenuation in a thin film.

    Science.gov (United States)

    Zhang, Xi-Jing; Fan, Xi-Zhi; Wang, Hui-Tian; He, Jing-Liang; Ming, N

    2002-12-16

    We present a simple and efficient technique for evaluating the optical losses of a planar film by use of a quasi-waveguide configuration and a prism film coupler configuration. The technique can separate two contributions to optical loss: that from the surface scattering caused by the roughness of surface and that from volume losses including volume scattering and volume absorption.

  2. Concentrating on Solar Power in a Trans-Mediterranean Renewable Energy Co-Operation

    Science.gov (United States)

    Trieb, F.; Kronshage, S.; Knies, G.

    2004-12-01

    Combining the large demand of clean electricity in Europe (EU) with the large potential of solar electricity generation from concentrating solar power stations (CSP) in the Middle East and North Africa (MENA) can provide both climate protection and development for both regions and lead to environmental, economical and social sustainability. The presentation will address the concept of solar cogeneration of electricity and desalted water and the scope of generating clean power for MENA and Europe while providing large quantities of freshwater for the MENA countries. Costs and benefits of the concept will be quantified, and the first steps to realisation within the Trans-Mediterranean Renewable Energy Co-Operation TREC are presented. After running through the technology learning curve within about 10-15 years, concentrated solar electricity will be generated at a cost of roughly 4 ct/kWh. Importing solar power from North Africa to Europe, will add 1 ct/kWh, thus being competitive with new fuel fired plants. The total initial support of about 1 billion € needed to trigger CSP market introduction and to achieve forever low electricity costs in the EU and MENA, equals 25 % of the German annual coal subsidies, 1 month of EU agronomic-subsidies or 1 day of US military expenses and could be provided in form of public investment, soft loans or feed-in guaranties like the German Renewable Energy Act.

  3. Effect of Oral Midazolam Premedication on Children's Co-operation Before General Anesthesia in Pediatric Dentistry.

    Science.gov (United States)

    Kaviani, Nasser; Shahtusi, Mina; Haj Norousali Tehrani, Maryam; Nazari, Sara

    2014-09-01

    Premedication is expedient in reducing the psychological trauma from recalling the unpleasant pre-anesthetic phases, hence, inducing a trouble-free anesthesia. This study aimed to determine the effectiveness of oral midazolam in co-operation of the subjects before general anesthesia and in recalling the pre-anesthetic phases, performed on children candidate for dental treatment under general anesthesia. In this prospective clinical trial study, 62 healthy non-cooperative children, candidate for dental treatment under general anesthesia, were randomly divided into study and control groups. The children received 20ml orange juice, 20 minutes before starting the anesthesia. The juice of the test group contained 0.5mg/kg of midazolam and that of the control group included no medication. The induction and the maintenance process of anesthesia were similar in both groups. The manner of subjects when separated from parents, their cooperation during intravenous catheterization, and recalling the pre-anesthetic events were recorded. Data were analyzed by adopting chi-square and Mann-Whitney tests. Most of the children in the test group had a comfortable separation from parents, restful IV catheterization and 90% of the subjects did not recall the pre-anesthetic events. Under the circumstances of this study, it could be concluded that 0.5mg/kg oral midazolam premedication is effective for comfortable separation of children from parents and restful IV catheterization and also forgetting the pre-anesthetic events.

  4. pH-induced kinetic co-operativity of a thylakoid-bound polyphenol oxidase.

    Science.gov (United States)

    Valero, E; García-Carmona, F

    1992-01-01

    A study of the catecholase activity of a latent plant polyphenol oxidase, extracted and purified from the chloroplast membranes of grapes (Vitis vinifera cv. Airen), revealed for the first time a lag phase above pH 5.0, whereas a steady-state rate was reached immediately when pH values were lower, thus suggesting the hysteretic nature of the enzyme. During steady state, the enzyme showed negative co-operativity concomitant with the presence of the lag period, and followed classical Michaelis-Menten kinetics under more acid pH conditions. Statistical analysis of these data showed a minimal value for the extreme Hill coefficient of 0.54 at pH 6.0. This kinetic behaviour of polyphenol oxidase has been interpreted in terms of the pH-induced 'slow' transition mechanism reported by Ricard, Noat & Nari [(1984) Eur. J. Biochem. 145, 311-317] in which the conformational change does not affect the active site of the enzyme. Images Fig. 4. PMID:1530593

  5. WHEN THE PATIENT IS UNWILLING OR UNABLE TO CO-OPERATE

    Directory of Open Access Journals (Sweden)

    Dušica Pleterski Rigler

    2001-09-01

    Full Text Available Background. Nowadays it is increasingly important for the physician to adequately inform the patient of his or her health situation, explain the options for treatment and obtain his or her consent. This principle is enshrined in the Oviedo Convention, a legal instrument with the power of law. Ethical questions arise when the patient is unwilling or unable to co-operate. Different problems are encountered with adult competent patients, in cases of limited mental capacity or with patients totally unable to consent. In children, the situation differs with age; adolescents’ opinion must be considered as increasingly important in decision making process, commensurate with their ability to understand and make rational choices. Specific ethical dilemmas arise with critically ill patients who refuse medical procedures or are unable to participate in medical decisions. Suicidal attempt cannot be taken to imply valid refusal of medical assistance.Conclusion. In exceptional situations when an appropriate informed consent cannot be obtained, the physician should take his decisions according to his best professional judgement and in the best interest of the patient.

  6. Employing Multiple Unmanned Aerial Vehicles for Co-Operative Path Planning

    Directory of Open Access Journals (Sweden)

    Durdana Habib

    2013-05-01

    Full Text Available Abstract In this paper, we work to develop a path planning solution for a group of Unmanned Aerial Vehicles (UAVs using a Mixed Integer Linear Programming (MILP approach. Co-operation among team members not only helps reduce mission time, it makes the execution more robust in dynamic environments. However, the problem becomes more challenging as it requires optimal resource allocation and is NP-hard. Since UAVs may be lost or may suffer significant damage during the course of the mission, plans may need to be modified in real-time as the mission proceeds. Therefore, multiple UAVs have a better chance of completing a mission in the face of failures. Such military operations can be treated as a variant of the Multiple Depot Vehicle Routing Problem (MDVRP. The proposed solution must be such that m UAVs start from multiple source locations to visit n targets and return to a set of destination locations such that (1 each target is visited exactly by one of the chosen UAVs (2 the total distance travelled by the group is minimized and (3 the number of targets that each UAV visits may not be less than K or greater than L.

  7. Testing and Evaluation of the Bear Medical Systems, Inc. Bear 33 Volume Ventilator System

    Science.gov (United States)

    1990-12-01

    the ventilator and humidifier were attached to a Michigan Instruments Model 1600 mechanical lung analyzer, which simulated the patient’s lungs. We...AD-A241 836 USAFSAM-TR-90-22 TESTING AND EVALUATION OF THE BEAR MEDICAL SYSTEMS, INC. BEAR 33 VOLUME VENTILATOR SYSTEM Teresa R. Lewis, Captain, USAF...Medical Systems, Inc. PE - 62202F Bear 33 Volume Ventilator System PR - 7930 6. AUTHOR(S) TA - 16 WU - 12 Teresa R. Lewis, and Thomas E. Philbeck, Jr. 7

  8. The Driving Forces and Economic Impact of Co-operative Membership: Empirical Evidence from the Mexican Coffee Sector

    NARCIS (Netherlands)

    Rodriguez Padron, B.; Ruben, R.; Burger, C.P.J.

    2012-01-01

    We identify key factors influencing membership of co-operative organisations in Mexico's coffee sector. We also determine the impact of membership on the incomes that are derived from coffee cultivation. Factors at all levels are found to be relevant: individual factors, family characteristics, farm

  9. Towards co-operative governance in the development and implementation of cross-sectoral policy: water policy as an example

    CSIR Research Space (South Africa)

    MacKay, HM

    2004-01-01

    Full Text Available to be established on the ground, and not just considered as some form of laudable principle. One of the most important steps in moving towards operational co-operative governance is the identification and agreement, by all the relevant and affected sectors...

  10. Student Perceptions of Social Learning Space: Designing and Implementing a Co-Operative Assessment Task in Pharmacology

    Science.gov (United States)

    Moni, Roger W.; Depaz, Iris; Lluka, Lesley J.

    2008-01-01

    We report findings from a case study of co-operative, group-based assessment in Pharmacology for second-year undergraduates at The University of Queensland, Australia. Students enrolled in the 2005 Bachelor of Science and 2006 Bachelor of Pharmacy degree programs, were early users of the university's new Collaborative Teaching and Learning Centre…

  11. The Effect of Interviewer Experience, Attitudes, Personality and Skills on Respondent Co-operation with Face-to-Face Surveys

    Directory of Open Access Journals (Sweden)

    Annette Jäckle

    2012-12-01

    Full Text Available This paper examines the role of interviewers' experience, attitudes, personality traits and inter-personal skills in determining survey co-operation, conditional on contact. We take the perspective that these characteristics influence interviewers' behaviour and hence influence the doorstep interaction between interviewer and sample member. Previous studies of the association between doorstep behaviour and co-operation have not directly addressed the role of personality traits and inter-personal skills and most have been based on small samples of interviewers. We use a large sample of 842 face-to-face interviewers working for a major survey institute and analyse co-operation outcomes for over 100,000 cases contacted by those interviewers over a 13-month period. We find evidence of effects of experience, attitudes, personality traits and inter-personal skills on co-operation rates. Several of the effects of attitudes and inter-personal skills are explained by differences in experience, though some independent effects remain. The role of attitudes, personality and skills seems to be greatest for the least experienced interviewers.

  12. Is the Ownership Structure Model a Decisive Determinant of Co-Operatives' Financial Success? A Financial Assessment

    NARCIS (Netherlands)

    Kalogeras, N.; Pennings, J.M.E.; Kuikman, J.; Doumpos, M.

    2011-01-01

    Abstract. In this paper, the financial/ownership structures of agribusiness co-operatives (co-ops) are analyzed in order to examine whether new co-op models perform better than the more traditional ones. The assessment procedure introduces a new financial decision-aid approach, which is based on

  13. A Co-operative Inquiry Into Generating, Describing, and Transforming Knowledge About De-escalation Practices in Mental Health Settings

    DEFF Research Database (Denmark)

    Berring, Lene Lauge; Hummelvoll, Jan Kåre; Pedersen, Liselotte

    2016-01-01

    De-escalation is concerned with managing violent behaviour without resorting to coercive measures. Co-operative Inquiry provided the conceptual basis for generating knowledge regarding de-escalation practices in acute mental health care settings. The research included service users and staff memb...

  14. IMPACT OF CO-OPERATION AND COMPETENCES ON THE INNOVATING BEHAVIOR: A MICRO-ECONOMETRIC STUDY OF THE FRENCH FIRMS

    Directory of Open Access Journals (Sweden)

    Mohamed Karim Kefi

    2012-01-01

    Full Text Available The analysis of innovative behavior is suited to several ways of comments. The economic literature emphasizes, in many cases, different effects of innovation in products and processes on international trade, growth, employment and the firms performance. However, little knowledge about the impacts of competence and inter-firms co-operation on the innovative behavior (products or/and processes. According to a more empirical approach, incorporating both the “cooperation’s effect” and “competence’s effect”, we have tried to explain such innovative behavior. The results which led this article can qualify some gains with regard to incentives for innovation on the one hand, and put into perspective a new approach to innovative behavior (cooperation / competence, which by joint analysis of co-operation agreements and skills can explain the development of these innovative behaviours, on the other. Based on our results and on limits and extensions associated with them, it appears that the innovative behavior of the firm (products, processes, or products & processes is not only a reflection of motivation strategic businesses, but also their types of skills underlying any engagement in a co-operation agreement. Thus, innovation policy unveils partly the interest shown by business groups (government, university with respect to the co-operation agreements in R & D.

  15. The Organisation for Economic Co-Operation and Development's International Early Learning Study: Opening for Debate and Contestation

    Science.gov (United States)

    Moss, Peter; Dahlberg, Gunilla; Grieshaber, Susan; Mantovani, Susanna; May, Helen; Pence, Alan; Rayna, Sylvie; Swadener, Beth Blue; Vandenbroeck, Michel

    2016-01-01

    The Organisation for Economic Co-operation and Development is initiating the International Early Learning Study, a cross-national assessment of early learning outcomes involving the testing of 5-year-old children in participating countries. The authors use this colloquium to inform members of the early childhood community about this project and to…

  16. Children's accidents, accident causation, and remedy : examples from Organisation for Economic Co-operation and Development OECD-countries.

    NARCIS (Netherlands)

    Levelt, P.B.M.

    1996-01-01

    In this paper children's accident data are presented. These data were drawn from the Organisation for Economic Co-operation and Development (OECD) International Road Traffic and Accident Database (IRTAD), completed with data on separate countries drawn from other sources. Gender differences in

  17. Glandular breast tissue volume by magnetic resonance imaging in 100 healthy peripubertal girls: evaluation of clinical Tanner staging

    National Research Council Canada - National Science Library

    Fugl, Louise; Hagen, Casper P; Mieritz, Mikkel G; Tinggaard, Jeanette; Fallentin, Eva; Main, Katharina M; Juul, Anders

    2016-01-01

    ...) has never been performed. Our objective was to report normative data of glandular breast tissue volume and validate the clinical evaluation of pubertal breast staging by MRI of breast tissue and to evaluate circulating...

  18. Value of volume measurements in evaluating abdominal aortic aneurysms growth rate and need for surgical treatment

    Energy Technology Data Exchange (ETDEWEB)

    Kontopodis, Nikolaos, E-mail: kontopodisn@yahoo.gr [Department of Vascular Surgery, University of Crete Medical School, Heraklion (Greece); Metaxa, Eleni, E-mail: emmetaxa@gmail.com [Institute of Applied and Computational Mathematics, Foundation for Research and Technology-Hellas, Heraklion, Crete (Greece); Papaharilaou, Yannis, E-mail: yannisp@iacm.forth.gr [Institute of Applied and Computational Mathematics, Foundation for Research and Technology-Hellas, Heraklion, Crete (Greece); Georgakarakos, Efstratios, E-mail: efstratiosgeorg@gmail.com [Vascular Surgery Department, “Demokritus” University of Thrace Medical School, Alexandroupolis (Greece); Tsetis, Dimitris, E-mail: tsetis@med.uoc.gr [Interventional Radiology Unit, Department of Radiology, University of Crete Medical School, Heraklion, Crete (Greece); Ioannou, Christos V., E-mail: ioannou@med.uoc.gr [Department of Vascular Surgery, University of Crete Medical School, Heraklion (Greece)

    2014-07-15

    Purpose: To examine whether indices other than the traditionally used abdominal aortic aneurysm (AAA) maximum diameter, such as AAA volume, intraluminal thrombus (ILT) thickness and ILT volume, may be superior to evaluate aneurismal enlargement. Materials and methods: Thirty-four small AAAs (initially presenting a maximum diameter <5.5 cm which is the threshold for surgical repair) with an initial and a follow-up CT were examined. Median increase and percentile annual change of these variables was calculated. Correlation between growth rates as determined by the new indices under evaluation and those of maximum diameter were assessed. AAAs were divided according to outcome (surveillance vs. elective repair after follow-up which is based on the maximum diameter criterion) and according to growth rate (high vs. low) based on four indices. Contingency between groups of high/low growth rate regarding each of the four indices on one hand and those regarding need for surgical repair on the other was assessed. Results: A strong correlation between growth rates of maximum diameter and those of AAA and ILT volumes could be established. Evaluation of contingency between groups of outcome and those of growth rate revealed significant associations only for AAA and ILT volumes. Subsequently AAAs with a rapid volumetric increase over time had a likelihood ratio of 10 to be operated compared to those with a slower enlargement. Regarding increase of maximum diameter, likelihood ratio between AAAs with rapid and those with slow expansion was only 3. Conclusion: Growth rate of aneurysms regarding 3Dimensional indices of AAA and ILT volumes is significantly associated with the need for surgical intervention while the same does not hold for growth rates determined by 2Dimensional indices of maximum diameter and ILT thickness.

  19. Quantitative evaluation of myocardial function by a volume-normalized map generated from relative blood flow

    Energy Technology Data Exchange (ETDEWEB)

    Fukami, Tadanori [Department of Bio-system Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Yamagata 992-8510 (Japan); Sato, Hidenori [Department of Bio-system Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Yamagata 992-8510 (Japan); Wu, Jin [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Lwin, Thet-Thet- [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Yuasa, Tetsuya [Department of Bio-system Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Yamagata 992-8510 (Japan); Kawano, Satoru [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Iida, Keiji [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Akatsuka, Takao [Department of Bio-system Engineering, Faculty of Engineering, Yamagata University, Yonezawa, Yamagata 992-8510 (Japan); Hontani, Hidekata [Department of Computer Science and Engineering, Nagoya Institute of Technology, Aichi 466-8555 (Japan); Takeda, Tohoru [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Tamura, Masao [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan); Yokota, Hiroshi [Graduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki 305-8575 (Japan)

    2007-07-21

    Our study aimed to quantitatively evaluate blood flow in the left ventricle (LV) of apical hypertrophic cardiomyopathy (APH) by combining wall thickness obtained from cardiac magnetic resonance imaging (MRI) and myocardial perfusion from single-photon emission computed tomography (SPECT). In this study, we considered paired MRI and myocardial perfusion SPECT from ten patients with APH and ten normals. Myocardial walls were detected using a level set method, and blood flow per unit myocardial volume was calculated using 3D surface-based registration between the MRI and SPECT images. We defined relative blood flow based on the maximum in the whole myocardial region. Accuracies of wall detection and registration were around 2.50 mm and 2.95 mm, respectively. We finally created a bull's-eye map to evaluate wall thickness, blood flow (cardiac perfusion) and blood flow per unit myocardial volume. In patients with APH, their wall thicknesses were over 10 mm. Decreased blood flow per unit myocardial volume was detected in the cardiac apex by calculation using wall thickness from MRI and blood flow from SPECT. The relative unit blood flow of the APH group was 1/7 times that of the normals in the apex. This normalization by myocardial volume distinguishes cases of APH whose SPECT images resemble the distributions of normal cases.

  20. In-human subject-specific evaluation of a control-theoretic plasma volume regulation model.

    Science.gov (United States)

    Bighamian, Ramin; Kinsky, Michael; Kramer, George; Hahn, Jin-Oh

    2017-12-01

    The goal of this study was to conduct a subject-specific evaluation of a control-theoretic plasma volume regulation model in humans. We employed a set of clinical data collected from nine human subjects receiving fluid bolus with and without co-administration of an inotrope agent, including fluid infusion rate, plasma volume, and urine output. Once fitted to the data associated with each subject, the model accurately reproduced the fractional plasma volume change responses in all subjects: the error between actual versus model-reproduced fractional plasma volume change responses was only 1.4 ± 1.6% and 1.2 ± 0.3% of the average fractional plasma volume change responses in the absence and presence of inotrope co-administration. In addition, the model parameters determined by the subject-specific fitting assumed physiologically plausible values: (i) initial plasma volume was estimated to be 36 ± 11 mL/kg and 37 ± 10 mL/kg in the absence and presence of inotrope infusion, respectively, which was comparable to its actual counterpart of 37 ± 4 mL/kg and 43 ± 6 mL/kg; (ii) volume distribution ratio, specifying the ratio with which the inputted fluid is distributed in the intra- and extra-vascular spaces, was estimated to be 3.5 ± 2.4 and 1.9 ± 0.5 in the absence and presence of inotrope infusion, respectively, which accorded with the experimental observation that inotrope could enhance plasma volume expansion in response to fluid infusion. We concluded that the model was equipped with the ability to reproduce plasma volume response to fluid infusion in humans with physiologically plausible model parameters, and its validity may persist even under co-administration of inotropic agents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. Performance evaluation of the technical capabilities of DOE sites for disposal of mixed low-level waste: Volume 3, Site evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Waters, R.D.; Gruebel, M.M. [eds.

    1996-03-01

    A team of analysts designed and conducted a performance evaluation to estimate the technical capabilities of fifteen Department of Energy sites for disposal of mixed low-level waste (i.e., waste that contains both low-level radioactive materials and hazardous constituents). Volume 1 summarizes the process for selecting the fifteen sites, the methodology used in the evaluation, and the conclusions derived from the evaluation. Volume 2 provides details about the site-selection process, the performance-evaluation methodology, and the overall results of the analysis. Volume 3 contains detailed evaluations of the fifteen sites and discussion of the results for each site.

  2. Technology evaluation report: Babcock and Wilcox Cyclone Furnace Vitrification technology. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Groeber, P.

    1992-09-01

    The Babcock and Wilcox (B and W) Cyclone Furnace Vitrification Technology is a treatment process for contaminated soils. The process was evaluated to determine its ability to destroy semivolatile organics and to isolate metals and simulated radionuclides into a non-leachable slag material. The feed material for the system was a prepared synthetic soil matrix (SSM) that was spiked with two organic compounds and six metals. This volume contains the appendices.

  3. Design and implementation of co-operative control strategy for hybrid AC/DC microgrids

    Science.gov (United States)

    Mahmud, Rasel

    This thesis is mainly divided in two major sections: 1) Modeling and control of AC microgrid, DC microgrid, Hybrid AC/DC microgrid using distributed co-operative control, and 2) Development of a four bus laboratory prototype of an AC microgrid system. At first, a distributed cooperative control (DCC) for a DC microgrid considering the state-of-charge (SoC) of the batteries in a typical plug-in-electric-vehicle (PEV) is developed. In DC microgrids, this methodology is developed to assist the load sharing amongst the distributed generation units (DGs), according to their ratings with improved voltage regulation. Subsequently, a DCC based control algorithm for AC microgrid is also investigated to improve the performance of AC microgrid in terms of power sharing among the DGs, voltage regulation and frequency deviation. The results validate the advantages of the proposed methodology as compared to traditional droop control of AC microgrid. The DCC-based control methodology for AC microgrid and DC microgrid are further expanded to develop a DCC-based power management algorithm for hybrid AC/DC microgrid. The developed algorithm for hybrid microgrid controls the power flow through the interfacing converter (IC) between the AC and DC microgrids. This will facilitate the power sharing between the DGs according to their power ratings. Moreover, it enables the fixed scheduled power delivery at different operating conditions, while maintaining good voltage regulation and improved frequency profile. The second section provides a detailed explanation and step-by-step design and development of an AC/DC microgrid testbed. Controllers for the three-phase inverters are designed and tested on different generation units along with their corresponding inductor-capacitor-inductor (LCL) filters to eliminate the switching frequency harmonics. Electric power distribution line models are developed to form the microgrid network topology. Voltage and current sensors are placed in the proper

  4. Deep Drilling Basic Research: Volume 5 - System Evaluations. Final Report, November 1988--August 1990

    Energy Technology Data Exchange (ETDEWEB)

    None

    1990-06-01

    This project is aimed at decreasing the costs and increasing the efficiency of drilling gas wells in excess of 15,000 feet. This volume presents a summary of an evaluation of various drilling techniques. Drilling solutions were compared quantitatively against typical penetration rates derived from conventional systems. A qualitative analysis measured the impact of a proposed system on the drilling industry. The evaluations determined that the best candidates f o r improving the speed and efficiency of drilling deep gas wells include: PDC/TSD bits, slim-hole drilling, roller-cone bits, downhole motors, top-driven systems, and coiled-tubing drilling.

  5. Developing and Evaluating Prototype of Waste Volume Monitoring Using Internet of Things

    Science.gov (United States)

    Fathhan Arief, Mohamad; Lumban Gaol, Ford

    2017-06-01

    In Indonesia, especially Jakarta have a lot of garbage strewn that can be an eyesore and also cause pollution that can carry diseases. Garbage strewn can cause many things, one of her dues is bins are overflowing due to the full so it can not accommodate the waste dumped from other people. Thus, the author created a new method for waste disposal more systematic. In creating new method requires a technology to supports, then the author makes a prototype for waste volume monitoring. By using the internet of things prototype of waste volume monitoring may give notification to the sanitary agency that waste in the trash bin needs to be disposal. In this study, conducted the design and manufactured of prototype waste volume monitoring using LinkItONE board based by Arduino and an ultrasonic sensor for appliance senses. Once the prototype is completed, evaluation in order to determine whether the prototype will function properly. The result showed that the expected function of a prototype waste volume monitoring can work well.

  6. Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy.

    Science.gov (United States)

    Knaup, Courtney; Mavroidis, Panayiotis; Stathakis, Sotirios; Smith, Mark; Swanson, Gregory; Papanikolaou, Niko

    2011-09-01

    This study evaluates low dose-rate brachytherapy (LDR) prostate plans to determine the biological effect of dose degradation due to prostate volume changes. In this study, 39 patients were evaluated. Pre-implant prostate volume was determined using ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1(®)) to create treatment plans using (103)Pd seeds. Following the implant, patients were imaged using CT for post-implant dosimetry. From the pre and post-implant DVHs, the biologically equivalent dose and the tumor control probability (TCP) were determined using the biologically effective uniform dose. The model used RBE = 1.75 and α/β = 2 Gy. The prostate volume changed between pre and post implant image sets ranged from -8% to 110%. TCP and the mean dose were reduced up to 21% and 56%, respectively. TCP is observed to decrease as the mean dose decreases to the prostate. The post-implant tumor dose was generally observed to decrease, compared to the planned dose. A critical uniform dose of 130 Gy was established. Below this dose, TCP begins to fall-off. It was also determined that patients with a small prostates were more likely to suffer TCP decrease. The biological effect of post operative prostate growth due to operative trauma in LDR was evaluated using the concept. The post-implant dose was lower than the planned dose due to an increase of prostate volume post-implant. A critical uniform dose of 130 Gy was determined, below which TCP begun to decline.

  7. Uterine volume and endometrial thickness in healthy girls evaluated by ultrasound (3-dimensional) and magnetic resonance imaging

    DEFF Research Database (Denmark)

    Hagen, Casper P; Mouritsen, Annette; Mieritz, Mikkel G

    2015-01-01

    OBJECTIVE: To report normative data on uterine volume and endometrial thickness in girls, according to pubertal stages; to evaluate factors that affect uterine volume; and to compare transabdominal ultrasound (TAUS) and magnetic resonance imaging (MRI). DESIGN: Cross-sectional study of a nested......). Uterine volume: ellipsoid TAUS (n = 112) and 3-dimensional TAUS (n = 111); ellipsoid MRI (n = 61). Endometrial thickness: TAUS (n = 110) and MRI (n = 60). RESULT(S): Uterine volume and endometrial thickness were positively correlated with pubertal stages; e.g., ellipsoid TAUS: r = 0.753, and endometrium......: ellipsoid volume (r = 0.891) and endometrial thickness (r = 0.540). Uterine volume was larger in TAUS compared with MRI; mean difference across the measured range: 7.7 (5.2-10.2) cm(3). Agreement was best for small uteri. CONCLUSION(S): Uterine volume and endometrial thickness increased as puberty...

  8. Inter-Firm Co-Operative Strategies In The Context Of Discontinuous Technological Change. The Case Of The Uk Optical Communications Systems Industry

    NARCIS (Netherlands)

    S. Spedale-Latimer (Simona)

    2002-01-01

    textabstractAt times of discontinuous technological change co-operation represents a viable strategy for both incumbents and new-entrants, provided that the choice of co-operation is consistent with the firm's business strategy (market-pull vs. technology-push) and with its degree of organizational

  9. Establishing cross-border co-operation between professional organizations: police, fire brigades and emergency health services in Dutch border regions

    NARCIS (Netherlands)

    Princen, S.; Geuijen, K.; Candel, J.J.L.; Folgerts, O.; Hooijer, R.

    2016-01-01

    This article explores the conditions under which local and regional governments will establish and sustain cross-border co-operation in the fields of police, fire fighting and emergency health services. It argues that understanding this type of cross-border co-operation requires a focus on the way

  10. Variations in life expectancy in Organization for Economic Co-operation and Development countries--1985-2010.

    Science.gov (United States)

    Zare, Hossein; Gaskin, Darrell J; Anderson, Gerard

    2015-12-01

    We examined the impact of different behavioral factors of health on the variations in the levels and rate of increase in life expectancy in Organization for Economic Co-operation and Development countries between 1985 and 2010. Using the World Health Organization's conceptual framework of socio-economic determinants of health, we incorporated Organization for Economic Co-operation and Development, World Bank and United Nations data to estimate the impact of these variables on life expectancy for 30 Organization for Economic Co-operation and Development countries. We used a random effect model to control the fixed effect of year and each country. Results show that the level of health care spending is the most important factor predicting life expectancy. Other important factors are gross domestic product per capita, labor productivity, years of schooling and percentage of gross domestic product spending allocated for public services. Life expectancy was reduced by smoking and higher daily calorie consumption. Countries that were previously part of the Soviet Union had lower life expectancies. Political factors had only a minor impact on life expectancy. Life expectancy increased an average of 5.1 years in Organization for Economic Co-operation and Development countries between 1985 and 2010, but there was wide variation. Health spending per capita, economic factors and two behavioral factors - smoking and caloric intake - explained most of the variation and suggest where increased policy attention could have the greatest impact on life expectancy. Policymakers who consider our estimates recognize that they may see greater or less impact depending on the characteristics of their nation. © 2015 the Nordic Societies of Public Health.

  11. A study of live supervisory phone-ins in family therapy: Correlates of client co-operation

    OpenAIRE

    Moorehouse, Adele; Carr, Alan

    2001-01-01

    The relationship between the parameters of live supervisory phone-ins and particular supervisory and therapy processes were examined in this study. The frequency of phone-ins and the number of suggestions made by supervisors were associated with specific therapist, supervisor and client behaviours. Less frequent phone-ins (5 or less per session) were associated with greater client co-operation, greater supervisor collaboration and, surprisingly, less therapist collaboration with c...

  12. Portal blood flow volume measurement in schistosomal patients: evaluation of Doppler ultrasonography reproducibility

    Energy Technology Data Exchange (ETDEWEB)

    Leao, Alberto Ribeiro de Souza; Santos, Jose Eduardo Mourao; Moulin, Danilo Sales; Shigueoka, David Carlos; D' Ippolito, Giuseppe [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Escola Paulista de Medicina. Dept. de Diagnostico por Imagem]. E-mail: ar.leao@uol.com.br; Colleoni, Ramiro [Universidade Federal de Sao Paulo (UNIFESP/EPM), SP (Brazil). Escola Paulista de Medicina. Dept. de Gastroenterologia

    2008-09-15

    Objective: To evaluate the reproducibility of Doppler ultrasonography in the measurement of portal blood flow volume in schistosomal patients. Materials and methods: Prospective, transversal, observational and self-paired study evaluating 21 patients with hepatosplenic schistosomiasis submitted to Doppler ultrasonography performed by three independent observers for measurement of portal blood flow. Pairwise interobserver agreement was calculated by means of the intraclass correlation coefficient, paired t-test and Pearson's correlation coefficient. Results: Interobserver agreement was excellent. Intraclass correlation ranged from 80.6% to 93.0% (IC at 95% [65.3% ; 95.8%]), with the Pearson's correlation coefficient ranging between 81.6% and 92.7% with no statistically significant interobserver difference regarding the mean portal blood flow volume measured by Doppler ultrasonography (p = 0.954 / 0.758 / 0.749). Conclusion: Doppler ultrasonography has demonstrated to be a reliable method for measuring the portal blood flow volume in patients with portal hypertension secondary to schistosomiasis, with a good interobserver agreement. (author)

  13. Anatomic evaluation of the membranous labyrinth by imaging: 3D-MRI volume-rendered reconstructions.

    Science.gov (United States)

    Miguéis, A; Melo Freitas, P; Cordeiro, M

    2007-01-01

    Recent advances in magnetic resonance imaging (MRI) technology has allowed the development of imaging sequences tailored to the assessment of minute anatomic detail of the temporal bone structures. Volume Rendering (VR) is a 3D rendering method used in MRI. It helps in understanding complex anatomic conditions and is particularly useful in the evaluation of tiny structures as the membranous labyrinth. The authors aimed at verifying the contribution of VR in the study of labyrinthine pathology in view of all the possible anatomic correlation. We performed 3D T2-weighted FSE MRI at 1.5 T with a dedicated surface coil, at high resolution (0.5 mm partition). All selected patients were volunteers and unknown for temporal bone pathology. The anatomy of the cochlea and vestibule were clearly defined. We could distinguish components of the cochlea to the level of the scala tympani, the vestibule and the cochlear duct. The saccule, utricle, endolymphatic duct and sac, and semicircular canals were also distinguished. Volume reconstructions yielded excellent spatial information regarding the cochlea, vestibule, semicircular canals and all three ampullae. Maximum Intensity Projection (MIP) images are useful as a preliminary study, to show eventual inner acoustic canal pathology and to provide information with the use of contrasting agents. We conclude therefore that VR seems to be essential in evaluating labyrinthine anatomy and pathology. Our results suggest that improved diagnostic information can be obtained by applying this volume visualization reconstruction technique in all inner ear neuroradiological protocols.

  14. Evaluation of bioimpedance spectroscopy for the measurement of body fluid compartment volumes in rats.

    Science.gov (United States)

    Hu, Lufei; Maslanik, Tom; Zerebeckyj, Mykolai; Plato, Craig F

    2012-03-01

    Bioimpedance spectroscopy (BIS) has been used in human and large animal research to assess body fluid compartment volumes (BFC) such as total body water (TBW), extracellular fluid volume (ECFV), and intracellular fluid volume (ICFV). To date, the application of BIS for determination of BFC in small research animals has been limited. We sought to evaluate the sensitivity and consistency of BIS for the determination of BFC in male SD rats. Thus, in separate series of experiments, we a) compared BFC values determined using BIS to BFC values obtained using radioisotope indicator dilution methods; b) examined day-to-day intra- and inter-rat BFC variability in small (267.8±5.4 g) and large (372.6±5.6 g) rats (n=8/group) as compared to empirical normative mammalian values; c) evaluated the sensitivity of BIS to detect time-dependent responses to repeated administration of a potent diuretic; and d) compared empirically generated BFC data to predicted osmotically-induced ECFV and ICFV shifts in response to i.v. administration of hypotonic (0.3%), isotonic (0.9%) or hypertonic (3.0%) saline (n=6/concentration). BFC values generated using radioisotope dilution agreed with those generated using BIS. BIS reliably detected differences between small and large rats (pmeasurements of BFC in rats of a) differing sizes, b) in response to therapeutic agents known to influence renal sodium handling and c) in response to osmotic challenge. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Climate protection in Germany`s bilateral development co-operation with the People`s Republic of China

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, A.

    1996-12-31

    For globally sustainable development to be achieved, three concerns are central: productive economic growth, social justice and ecological sustainability. Development co-operation supports the realisation of these three goals in partner countries by helping to alleviate poverty, promote economic growth through private-sector development and protect vital natural resources. The aim of globally sustainable development can only be achieved if industrial countries too implement necessary reforms and structural adjustments at every level. Co-operation efforts with partners must therefore be complemented by coherent policies at home. This is a matter of credibility, but also of developmental far-sightedness. Internal reforms in the industrial countries secure financial leeway for their providing foreign assistance in the longer term. Environmental and resource protection as a focal point of Germany`s development co-operation with the PRC aims to preserve vital natural resources, shape economic development in their partner countries in an ecologically sound manner and put China in a position to participate in global endeavours to protect the environment. Climate protection measures figure prominently in this area. This is justified given China`s share of global CO{sub 2} emissions and the potential for energy-saving measures and measures to increase power intensity. This potential is derived primarily from the possibility of using energy-efficient technologies, increasing the relatively low energy prices and making use of renewable sources of energy.

  16. Radiologic evaluation for volume and weight of remnant lung in living lung donors.

    Science.gov (United States)

    Mizobuchi, Teruaki; Chen, Fengshi; Yoshino, Ichiro; Iwata, Takekazu; Yoshida, Shigetoshi; Bando, Toru; Date, Hiroshi

    2013-11-01

    Living-lung donors lose pulmonary function of a right or left lower lobe in exchange for a noble donation; however, Chen and colleagues reported postoperative pulmonary function of the donors was significantly better than the estimated values. The purpose of this study was to investigate if the improvement of postoperative pulmonary function is associated with hypertrophic phenomena of remnant lung. A total of 35 patients who underwent a right or left lower lobectomy for living-donor lobar lung transplantation in Kyoto University Hospital from 2008 to 2011 were evaluated by means of spirometry (forced vital capacity, forced expiratory volume in 1 second, and diffusing capacity for carbon monoxide), and computed tomography scans both before and 1 year after the surgery. Postoperative predictions of pulmonary function and radiologic parameters were made based on the number of resected segments. The average radiologic density of the lung was determined as follows: (mean computed tomography number + 1000)/1000, and weight of the lung was calculated as follows: lung volume (mL) × average radiologic lung density (g/mL). The radiologic analysis was performed on both the surgical and contralateral sides. Postoperative forced vital capacity, forced expiratory volume in 1 second, and diffusing capacity for carbon monoxide were significantly higher than estimated values by 17.3% ± 10.2% (P lung volume and weight of the surgical side were significantly higher than estimated values by 54.4% ± 30.4% (P lung volume was significantly higher than the estimated value by 12.6% ± 15.3% (P lung may be recognized in living lung donors. Copyright © 2013 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  17. Energy extension service pilot program evaluation report: the first year. Volume II: pilot state reports

    Energy Technology Data Exchange (ETDEWEB)

    1979-09-01

    Volume II of the Energy Extension Service Evaluation presents a discussion of the operations of the ten EES pilot-state programs during the period from October 1, 1977 through September 30, 1978. Each of the ten pilot states - Alabama, Connecticut, Michigan, New Mexico, Pennsylvania, Tennessee, Texas, Washington, Wisconsin, and Wyoming - received a grant of approximately $1.1 million to develop and implement a 19-month program beginning on October 1, 1977. Volume II provides a case-study description of the operations of the pilot program in each state, with special attention given to the two programs selected in each state for more detailed study and survey research. Some survey data and analysis are presented for the emphasis programs.

  18. Classical and recent free-volume models for polymer solutions: A comparative evaluation

    DEFF Research Database (Denmark)

    Radfarnia, H.R.; Kontogeorgis, Georgios; Ghotbi, C.

    2007-01-01

    for aqueous and alcohol solutions, based on the physical values of the van der Waals volume and surface areas for both FV-combinatorial and residual contributions. The prediction results of both "recent" and "classical" FV models using the new regressed energy parameters are significantly better, compared......In this work, two "classical" (UNIFAC-FV, Entropic-FV) and two "recent" free-volume (FV) models (Kannan-FV, Freed-FV) are comparatively evaluated for polymer-solvent vapor-liquid equilibria including both aqueous and non-aqueous solutions. Moreover, some further developments are presented here...... by the modified Freed-FV model for athermal and non-athermal polymer systems are compared to other "recent" and "classical" FV models, indicating an improvement for the modified Freed-FV model for aqueous polymer solutions. Second, for the original Freed-FV model, new UNIFAC group energy parameters are regressed...

  19. Functional evaluation of corneal endothelium by combined measurement of corneal volume alteration and cell density after phacoemulsification.

    Science.gov (United States)

    Suzuki, Hisaharu; Oki, Kotaro; Takahashi, Keizo; Shiwa, Toshihiko; Takahashi, Hiroshi

    2007-12-01

    To assess a new method of functional evaluation of corneal endothelium using combined measurement of corneal volume alteration and cell density (CD) after phacoemulsification. Nippon Medical School Hospital, Tokyo, Japan. Phacoemulsification was performed in 28 cases. The corneal volume within 3.0 mm and 10.0 mm circles of the cornea was measured using Scheimpflug imaging (Pentacam, Oculus, Inc.) and the cell density, using specular microscopy (Noncon Robo, Konan Medical). The volume stress index (VSI), a parameter for measuring functional evaluation, was calculated by dividing the volume increase within the 3.0 mm circle (preoperative corneal volume - corneal volume at time of measurement) by the central cell density value. The resulting value is indicative of the amount of postoperative increase in corneal volume with which each corneal endothelial cell should be able to cope. Three months after surgery, the 3.0 mm corneal volume returned to preoperative values, while the 10.0 mm corneal volume remained significantly higher than preoperatively. The cell density values did not significantly change throughout the study. The VSI showed a significant decrease by 7 days after surgery followed by a gradual decrease until the end of the study. At 3 months, the VSI value was significantly smaller than at 1 day. The corneal volume increase after surgery may be indicative of the degree of the endothelial damage in the area; thus, the VSI may be useful in the functional assessment of the corneal endothelium.

  20. Evaluation of Regional White Matter Volume Reduction after Diffuse Axonal Injury using Voxel-based Morphometry.

    Science.gov (United States)

    Uruma, Go; Hashimoto, Keiji; Abo, Masahiro

    2015-01-01

    We developed a new and convenient method that employs voxel-based morphometry (VBM) to evaluate regional reduction in the volume of white matter after diffuse axonal injury (DAI). We studied 29 patients with moderate cognitive disability after DAI. Each subject underwent 3-dimensional volumetric magnetic resonance (MR) imaging. Images were preprocessed automatically using stand-alone software running on a Windows PC for VBM of volumetric MR imaging utilizing a statistical parametric mapping (SPM) version 8 software engine and an algorithm for diffeomorphic anatomic registration through exponentiated lie algebra (DARTEL). We then computed a Z-score for all coordinates on the white matter, which represented the relative reduction in white matter volume. Finally, we used voxel-based stereotactic extraction estimation (vbSEE) to compute the extent of regional reduction in the volume of white matter (rWMVR) for each region of interest (ROI), defined as the rate of coordinates with Z-scores exceeding 2.0 in the ROI. For each ROI, we used Pearson's correlation analysis to examine the correlation between the extent of regional volume reduction and patient scores on the Wechsler Adult Intelligence Scale III (WAIS-III). We detected marked rWMVR in several ROIs, including the corpus callosum, and rWMVR correlated significantly with performance IQ and processing speed index in the splenium of the corpus callosum. The results indicate the utility of our applications for the daily clinical evaluation of DAI. That they can be used on a PC and allow acquisition of volumetric data from standard MR images are their advantages.

  1. Metabolic tumour volumes measured at staging in lymphoma: methodological evaluation on phantom experiments and patients

    Energy Technology Data Exchange (ETDEWEB)

    Meignan, Michel [Hopital Henri Mondor and Paris-Est University, Department of Nuclear Medicine, Creteil (France); Paris-Est University, Service de Medecine Nucleaire, EAC CNRS 7054, Hopital Henri Mondor AP-HP, Creteil (France); Sasanelli, Myriam; Itti, Emmanuel [Hopital Henri Mondor and Paris-Est University, Department of Nuclear Medicine, Creteil (France); Casasnovas, Rene Olivier [CHU Le Bocage, Department of Hematology, Dijon (France); Luminari, Stefano [University of Modena and Reggio Emilia, Department of Diagnostic, Clinic and Public Health Medicine, Modena (Italy); Fioroni, Federica [Santa Maria Nuova Hospital-IRCCS, Department of Medical Physics, Reggio Emilia (Italy); Coriani, Chiara [Santa Maria Nuova Hospital-IRCCS, Department of Radiology, Reggio Emilia (Italy); Masset, Helene [Henri Mondor Hospital, Department of Radiophysics, Creteil (France); Gobbi, Paolo G. [University of Pavia, Department of Internal Medicine and Gastroenterology, Fondazione IRCCS Policlinico San Matteo, Pavia (Italy); Merli, Francesco [Santa Maria Nuova Hospital-IRCCS, Department of Hematology, Reggio Emilia (Italy); Versari, Annibale [Santa Maria Nuova Hospital-IRCCS, Department of Nuclear Medicine, Reggio Emilia (Italy)

    2014-06-15

    The presence of a bulky tumour at staging on CT is an independent prognostic factor in malignant lymphomas. However, its prognostic value is limited in diffuse disease. Total metabolic tumour volume (TMTV) determined on {sup 18}F-FDG PET/CT could give a better evaluation of the total tumour burden and may help patient stratification. Different methods of TMTV measurement established in phantoms simulating lymphoma tumours were investigated and validated in 40 patients with Hodgkin lymphoma and diffuse large B-cell lymphoma. Data were processed by two nuclear medicine physicians in Reggio Emilia and Creteil. Nineteen phantoms filled with {sup 18}F-saline were scanned; these comprised spherical or irregular volumes from 0.5 to 650 cm{sup 3} with tumour-to-background ratios from 1.65 to 40. Volumes were measured with different SUVmax thresholds. In patients, TMTV was measured on PET at staging by two methods: volumes of individual lesions were measured using a fixed 41 % SUVmax threshold (TMTV{sub 41}) and a variable visually adjusted SUVmax threshold (TMTV{sub var}). In phantoms, the 41 % threshold gave the best concordance between measured and actual volumes. Interobserver agreement was almost perfect. In patients, the agreement between the reviewers for TMTV{sub 41} measurement was substantial (ρ {sub c} = 0.986, CI 0.97 - 0.99) and the difference between the means was not significant (212 ± 218 cm{sup 3} for Creteil vs. 206 ± 219 cm{sup 3} for Reggio Emilia, P = 0.65). By contrast the agreement was poor for TMTV{sub var}. There was a significant direct correlation between TMTV{sub 41} and normalized LDH (r = 0.652, CI 0.42 - 0.8, P <0.001). Higher disease stages and bulky tumour were associated with higher TMTV{sub 41}, but high TMTV{sub 41} could be found in patients with stage 1/2 or nonbulky tumour. Measurement of baseline TMTV in lymphoma using a fixed 41% SUVmax threshold is reproducible and correlates with the other parameters for tumour mass evaluation

  2. Predicting effective pro-apoptotic anti-leukaemic drug combinations using co-operative dynamic BH3 profiling.

    Directory of Open Access Journals (Sweden)

    Martin Grundy

    Full Text Available The BH3-only apoptosis agonists BAD and NOXA target BCL-2 and MCL-1 respectively and co-operate to induce apoptosis. On this basis, therapeutic drugs targeting BCL-2 and MCL-1 might have enhanced activity if used in combination. We identified anti-leukaemic drugs sensitising to BCL-2 antagonism and drugs sensitising to MCL-1 antagonism using the technique of dynamic BH3 profiling, whereby cells were primed with drugs to discover whether this would elicit mitochondrial outer membrane permeabilisation in response to BCL-2-targeting BAD-BH3 peptide or MCL-1-targeting MS1-BH3 peptide. We found that a broad range of anti-leukaemic agents-notably MCL-1 inhibitors, DNA damaging agents and FLT3 inhibitors-sensitise leukaemia cells to BAD-BH3. We further analysed the BCL-2 inhibitors ABT-199 and JQ1, the MCL-1 inhibitors pladienolide B and torin1, the FLT3 inhibitor AC220 and the DNA double-strand break inducer etoposide to correlate priming responses with co-operative induction of apoptosis. ABT-199 in combination with pladienolide B, torin1, etoposide or AC220 strongly induced apoptosis within 4 hours, but the MCL-1 inhibitors did not co-operate with etoposide or AC220. In keeping with the long half-life of BCL-2, the BET domain inhibitor JQ1 was found to downregulate BCL-2 and to prime cells to respond to MS1-BH3 at 48, but not at 4 hours: prolonged priming with JQ1 was then shown to induce rapid cytochrome C release when pladienolide B, torin1, etoposide or AC220 were added. In conclusion, dynamic BH3 profiling is a useful mechanism-based tool for understanding and predicting co-operative lethality between drugs sensitising to BCL-2 antagonism and drugs sensitising to MCL-1 antagonism. A plethora of agents sensitised cells to BAD-BH3-mediated mitochondrial outer membrane permeabilisation in the dynamic BH3 profiling assay and this was associated with effective co-operation with the BCL-2 inhibitory compounds ABT-199 or JQ1.

  3. Evaluation of PET/MRI for Tumor Volume Delineation for Head and Neck Cancer.

    Science.gov (United States)

    Wang, Kyle; Mullins, Brandon T; Falchook, Aaron D; Lian, Jun; He, Kelei; Shen, Dinggang; Dance, Michael; Lin, Weili; Sills, Tiffany M; Das, Shiva K; Huang, Benjamin Y; Chera, Bhishamjit S

    2017-01-01

    Computed tomography (CT), combined positron emitted tomography and CT (PET/CT), and magnetic resonance imaging (MRI) are commonly used in head and neck radiation planning. Hybrid PET/MRI has garnered attention for potential added value in cancer staging and treatment planning. Herein, we compare PET/MRI vs. planning CT for head and neck cancer gross tumor volume (GTV) delineation. We prospectively enrolled patients with head and neck cancer treated with definitive chemoradiation to 60-70 Gy using IMRT. We performed pretreatment contrast-enhanced planning CT and gadolinium-enhanced PET/MRI. Primary and nodal volumes were delineated on planning CT (GTV-CT) prospectively before treatment and PET/MRI (GTV-PET/MRI) retrospectively after treatment. GTV-PET/MRI was compared to GTV-CT using separate rigid registrations for each tumor volume. The Dice similarity coefficient (DSC) metric evaluating spatial overlap and modified Hausdorff distance (mHD) evaluating mean orthogonal distance difference were calculated. Minimum dose to 95% of GTVs (D95) was compared. Eleven patients were evaluable (10 oropharynx, 1 larynx). Nine patients had evaluable primary tumor GTVs and seven patients had evaluable nodal GTVs. Mean primary GTV-CT and GTV-PET/MRI size were 13.2 and 14.3 cc, with mean intersection 8.7 cc, DSC 0.63, and mHD 1.6 mm. D95 was 65.3 Gy for primary GTV-CT vs. 65.2 Gy for primary GTV-PET/MRI. Mean nodal GTV-CT and GTV-PET/MRI size were 19.0 and 23.0 cc, with mean intersection 14.4 cc, DSC 0.69, and mHD 2.3 mm. D95 was 62.3 Gy for both nodal GTV-CT and GTV-PET/MRI. In this series of patients with head and neck (primarily oropharynx) cancer, PET/MRI and CT-GTVs had similar volumes (though there were individual cases with larger differences) with overall small discrepancies in spatial overlap, small mean orthogonal distance differences, and similar radiation doses.

  4. Evaluation of Neonatal Lung Volume Growth by Pulmonary Magnetic Resonance Imaging in Patients with Congenital Diaphragmatic Hernia.

    Science.gov (United States)

    Schopper, Melissa A; Walkup, Laura L; Tkach, Jean A; Higano, Nara S; Lim, Foong Yen; Haberman, Beth; Woods, Jason C; Kingma, Paul S

    2017-09-01

    To evaluate postnatal lung volume in infants with congenital diaphragmatic hernia (CDH) and determine if a compensatory increase in lung volume occurs during the postnatal period. Using a novel pulmonary magnetic resonance imaging method for imaging neonatal lungs, the postnatal lung volumes in infants with CDH were determined and compared with prenatal lung volumes obtained via late gestation magnetic resonance imaging. Infants with left-sided CDH (2 mild, 9 moderate, and 1 severe) were evaluated. The total lung volume increased in all infants, with the contralateral lung increasing faster than the ipsilateral lung (mean ± SD: 4.9 ± 3.0 mL/week vs 3.4 ± 2.1 mL/week, P = .005). In contrast to prenatal studies, the volume of lungs of infants with more severe CDH grew faster than the lungs of infants with more mild CDH (Spearman's ρ=-0.086, P = .01). Although the contralateral lung volume grew faster in both mild and moderate groups, the majority of total lung volume growth in moderate CDH came from increased volume of the ipsilateral lung (42% of total lung volume increase in the moderate group vs 32% of total lung volume increase in the mild group, P = .09). Analysis of multiple clinical variables suggests that increased weight gain was associated with increased compensatory ipsilateral lung volume growth (ρ = 0.57, P = .05). These results suggest a potential for postnatal catch-up growth in infants with pulmonary hypoplasia and suggest that weight gain may increase the volume growth of the more severely affected lung. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Oak Ridge National Laboratory Technology Logic Diagram. Volume 1, Technology Evaluation: Part B, Remedial Action

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Oak Ridge National Laboratory Technology Logic Diagram (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) and waste management (WM) problems at Oak Ridge National Laboratory (ORNL) to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed to develop these technologies to a state that allows technology transfer and application to decontamination and decommissioning (D&D), remedial action (RA), and WM activities. The TLD consists of three fundamentally separate volumes: Vol. 1 (Technology Evaluation), Vol. 2 (Technology Logic Diagram), and Vol. 3 (Technology Evaluation Data Sheets). Part A of Vols. 1 and 2 focuses on D&D. Part B of Vols. 1 and 2 focuses on RA of contaminated facilities. Part C of Vols. 1 and 2 focuses on WM. Each part of Vol. 1 contains an overview of the TLD, an explanation of the program-specific responsibilities, a review of identified technologies, and the ranking os remedial technologies. Volume 2 (Pts. A, B, and C) contains the logic linkages among EM goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 3 (Pts. A, B, and C) contains the TLD data sheets. The focus of Vol. 1, Pt. B, is RA, and it has been divided into six chapters. The first chapter is an introduction, which defines problems specific to the ER Program for ORNL. Chapter 2 provides a general overview of the TLD. Chapters 3 through 5 are organized into necessary subelement categories: RA, characterization, and robotics and automation. The final chapter contains regulatory compliance information concerning RA.

  6. [Usefulness of left atrial diametres and volumes for the evaluation of left ventricular diastolic function].

    Science.gov (United States)

    Vizzardi, Enrico; Bonadei, Ivano; Teli, Melissa; Caretta, Giorgio; Maiandi, Cristian; Madureri, Alberto; Bordonali, Tania; Chiari, Ermanna; Raddino, Riccardo; Cas, Livio Dei

    2009-06-01

    The diastolic function of the left ventricle is a main point of the physiological adaptations of the cardiovascular system to the various situations. Evaluation of left atrium diameter change during diastole and left atrial volume and their possible correlation with different left ventricular diastolic filling pattern. Ninety patients with echocardiographically determined diastolic dysfunction and eighty healthy volunteers were included in the study. We measured left atrium emptying fraction (LAEF), defined as ratio of end-diastolic left atrial diameter to end-systolic diameter and left atrial volume. Mitral flow pulsed wave velocities were recorded. E, A, E/A, deceleration time of early diastolic filling, isovolumetric relaxation time were measured. Pulmonary vein S, D and atrial reversal velocities and tissue Doppler imaging of E' and A' mitral anular velocities were obtained. LAEF was found 0.6 +/- 0.4 (mean SE) in the control group, 0.81 +/- 0.04 in pseudonormal pattern (P E group (P E pattern group). LAEF and atrial volume are a new and practical methods for the differentiation of the normal-pseudonormal mitral flow pattern, in particular in setting without new ultrasound technologies.

  7. Technology evaluation report: Babcock and Wilcox Cyclone Furnace Vitrification technology. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Groeber, P.

    1992-09-01

    The project consists of an analysis of the Babcock and Wilcox (B and W) Cyclone Furnace Vitrification process. The SITE Demonstration took place at the B and W Research and Development Division in Alliance, Ohio. The vitrification process was performed on a synthetic soil matrix (SSM) that was spiked with known concentrations of semivolatile organic compounds, metals, and simulated radionuclides. The Demonstration effort was directed at obtaining information on the performance and cost of the process for use at other sites. Documentation will consist of two reports. This Technology Evaluation Report (TER) is contained in two volumes and describes the field activities and laboratory results.

  8. Coal liquefaction process streams characterization and evaluation. Volume 2, Participants program final summary evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Brandes, S.D.; Robbins, G.A.; Winschel, R.A.; Burke, F.P.

    1994-05-01

    This 4.5-year project consisted of routine analytical support to DOE`s direct liquefaction process development effort (the Base Program), and an extensive effort to develop, demonstate, and apply new analytical methods for the characterization of liquefaction process streams (the Participants Program). The objective of the Base Program was to support the on-going DOE direct coal liquefaction process development program. Feed, process, and product samples were used to assess process operations, product quality, and the effects of process variables, and to direct future testing. The primary objective of the Participants Program was to identify and demonstrate analytical methods for use in support of liquefaction process develpment, and in so doing, provide a bridge between process design, development, and operation and analytical chemistry. To achieve this direct coal liquefaction-derived materials. CONSOL made an evaluation of each analytical technique. During the performance of this project, we obtained analyses on samples from numerous process development and research programs and we evaluated a variety of analytical techniques for their usefulness in supporting liquefaction process development. Because of the diverse nature of this program, we provide here an annotated bibliography of the technical reports, publications, and formal presentations that resulted from this program to serve as a comprehensive summary of contract activities.

  9. Evaluation of bronchoscopic lung volume reduction coil treatment results in patients with severe emphysema.

    Science.gov (United States)

    Gulsen, Askin; Sever, Fidan; Girgin, Pelin; Tamci, Necdet Batuhan; Yilmaz, Hatice

    2017-09-01

    Bronchoscopic lung volume reduction coil (BLVR-C) implantation is an alternative therapeutic approach that can be applied together with medical treatment for patients with severe emphysema. BLVR-C is both easier and safer in terms of complications than volume reduction surgery. This study aimed to evaluate medium-term outcomes following BLVR-C treatment. Forty patients who underwent BLVR-C between September 2013 and March 2014 were reviewed retrospectively. We compared changes between the baseline and 6-month post-procedural results with respect to pulmonary function tests, a 6-min walk test (6MWT), chronic obstructive pulmonary disease (COPD) assessment test (CAT), St. George's Respiratory Questionnaire (SGRQ), and pulmonary artery pressure (PAP) and arterial blood gas analyses. Secondary outcomes included procedure-related and follow-up complications. An average of 9.5 (range: 5-11) coils were placed per lung in an average procedural duration of 20.8 ± 7.0 min (range: 9-45) min. Six months after BLVR-C treatment, significant improvements were observed in patients' pulmonary function tests and quality of life. Changes were observed in the forced exhalation volume in 1 s (+150 mL), residual volume (-14.5%), 6MWT (+48 m), SGRQ (-10.5) and CAT Score (-7.5). Changes in the PAP and partial pressure of carbon dioxide values were not significant, and pneumothorax did not occur. In a 6-month follow-up, 11 cases of COPD exacerbation (41.4%), 7 cases of pneumonia (16.9%) and 1 death (2%) occurred. Treatment in 1 case was postponed because of hypotension and bradycardia during the process. BLVR-C treatment appears to be effective over the medium-term and safe for patients with severe emphysema. © 2015 John Wiley & Sons Ltd.

  10. Evaluation of the effect of prostate volume change on tumor control probability in LDR brachytherapy

    Directory of Open Access Journals (Sweden)

    Courtney Knaup

    2011-09-01

    Full Text Available Purpose: This study evaluates low dose-rate brachytherapy (LDR prostate plans to determine the biological effectof dose degradation due to prostate volume changes. Material and methods: In this study, 39 patients were evaluated. Pre-implant prostate volume was determinedusing ultrasound. These images were used with the treatment planning system (Nucletron Spot Pro 3.1® to create treatmentplans using 103Pd seeds. Following the implant, patients were imaged using CT for post-implant dosimetry. Fromthe pre and post-implant DVHs, the biologically equivalent dose and the tumor control probability (TCP were determinedusing the biologically effective uniform dose. The model used RBE = 1.75 and α/β = 2 Gy. Results: The prostate volume changed between pre and post implant image sets ranged from –8% to 110%. TCP andthe mean dose were reduced up to 21% and 56%, respectively. TCP is observed to decrease as the mean dose decreasesto the prostate. The post-implant tumor dose was generally observed to decrease, compared to the planned dose.A critical uniform dose of 130 Gy was established. Below this dose, TCP begins to fall-off. It was also determined thatpatients with a small prostates were more likely to suffer TCP decrease. Conclusions: The biological effect of post operative prostate growth due to operative trauma in LDR was evaluatedusing the concept. The post-implant dose was lower than the planned dose due to an increase of prostate volumepost-implant. A critical uniform dose of 130 Gy was determined, below which TCP begun to decline.

  11. Cosmetic evaluation following volume replacement using lateral tissue flap in breast-conserving surgery.

    Science.gov (United States)

    Morishima, Hirotaka; Matsunami, Nobuki; Hasegawa, Junichi; Mikata, Shoki; Shimizu, Junzo; Kim, Yokoku; Hirota, Masaki; Mokutani, Yukako; Araki, Mariko; Miyake, Yuichiro; Nezu, Riichiro

    2014-01-01

    We examined the effectiveness of volume replacement using a lateral tissue flap (LTF) in breast-conserving surgery for a good cosmetic outcome. We analyzed the results of 130 patients with breast cancer who underwent breast-conserving surgery with replacement using an LTF from 2006 to 2010 with cosmetic evaluations performed according to the criteria of the Japanese Breast Cancer Society. We examined scores with regard to the following possible contributing factors: partial resection (Bp) or quadrantectomy (Bq), diameter of the specimen, body mass index (BMI), axillary lymphadenectomy, postoperative irradiation, and position of the tumor. The scores for cases with Bp and non-postoperative irradiation were higher than those for Bq and postoperative irradiation cases, though they were not significant factors in multivariate analysis. A negative correlation was seen between score and diameter of the specimen, whereas there was no significant correlation with BMI. There was no significant difference between scores of cases with or without an axillary lymphadenectomy. However, the score for the extended upper-outer area including the upper and outer borders was significantly higher than scores for other portions. In multiple regression analysis, cases with a tumor diameter less than 4 cm in the extended upper-outer area or less than 2 cm in other areas showed good adaptation. Tumor location and diameter are important factors for cosmetic evaluation of volume replacement using an LTF.

  12. Evaluation of bias-correction methods for ensemble streamflow volume forecasts

    Directory of Open Access Journals (Sweden)

    T. Hashino

    2007-01-01

    Full Text Available Ensemble prediction systems are used operationally to make probabilistic streamflow forecasts for seasonal time scales. However, hydrological models used for ensemble streamflow prediction often have simulation biases that degrade forecast quality and limit the operational usefulness of the forecasts. This study evaluates three bias-correction methods for ensemble streamflow volume forecasts. All three adjust the ensemble traces using a transformation derived with simulated and observed flows from a historical simulation. The quality of probabilistic forecasts issued when using the three bias-correction methods is evaluated using a distributions-oriented verification approach. Comparisons are made of retrospective forecasts of monthly flow volumes for a north-central United States basin (Des Moines River, Iowa, issued sequentially for each month over a 48-year record. The results show that all three bias-correction methods significantly improve forecast quality by eliminating unconditional biases and enhancing the potential skill. Still, subtle differences in the attributes of the bias-corrected forecasts have important implications for their use in operational decision-making. Diagnostic verification distinguishes these attributes in a context meaningful for decision-making, providing criteria to choose among bias-correction methods with comparable skill.

  13. Response-probability volume histograms and iso-probability of response charts in treatment plan evaluation.

    Science.gov (United States)

    Mavroidis, Panayiotis; Ferreira, Brigida Costa; Lopes, Maria do Carmo

    2011-05-01

    This study aims at demonstrating a new method for treatment plan evaluation and comparison based on the radiobiological response of individual voxels. This is performed by applying them on three different cancer types and treatment plans of different conformalities. Furthermore, their usefulness is examined in conjunction with traditionally applied radiobiological and dosimetric treatment plan evaluation criteria. Three different cancer types (head and neck, breast and prostate) were selected to quantify the benefits of the proposed treatment plan evaluation method. In each case, conventional conformal radiotherapy (CRT) and intensity modulated radiotherapy (IMRT) treatment configurations were planned. Iso-probability of response charts was produced by calculating the response probability in every voxel using the linear-quadratic-Poisson model and the dose-response parameters of the corresponding structure to which this voxel belongs. The overall probabilities of target and normal tissue responses were calculated using the Poisson and the relative seriality models, respectively. The 3D dose distribution converted to a 2 Gy fractionation, D2(GY) and iso-BED distributions are also shown and compared with the proposed methodology. Response-probability volume histograms (RVH) were derived and compared with common dose volume histograms (DVH). The different dose distributions were also compared using the complication-free tumor control probability, P+, the biologically effective uniform dose, D, and common dosimetric criteria. 3D Iso-probability of response distributions is very useful for plan evaluation since their visual information focuses on the doses that are likely to have a larger clinical effect in that particular organ. The graphical display becomes independent of the prescription dose highlighting the local radiation therapy effect in each voxel without the loss of important spatial information. For example, due to the exponential nature of the Poisson

  14. Substantial interobserver variation of thyroid volume and function by visual evaluation of thyroid (99m)Tc scintigraphy

    DEFF Research Database (Denmark)

    Soelberg, Kerstin; Grupe, Peter; Boel-Jørgensen, Henrik

    2014-01-01

    (99m)Tc-pertechnetate scintigraphy is much used in the evaluation of patients with nodular goitre. We investigated the ability of experienced observers to estimate the thyroid 24-h (131)I uptake (RAIU) and the thyroid volume by visual evaluation of the scintigram.......(99m)Tc-pertechnetate scintigraphy is much used in the evaluation of patients with nodular goitre. We investigated the ability of experienced observers to estimate the thyroid 24-h (131)I uptake (RAIU) and the thyroid volume by visual evaluation of the scintigram....

  15. Conceptions of curriculum in co-operative education: a framework for analysis of the co-op preparatory curriculum

    OpenAIRE

    Davidge-Johnston, Nancy Lee

    2007-01-01

    The model of co-operative education has been part of higher education for one hundred years with relatively little attention paid to its curriculum. Given the significant changes in the co-op “landscape” over this same time, a thorough review of the co-op curriculum is in order to ensure its relevance to a contemporary model of post-secondary education. This analysis explores the literature regarding learning and curriculum to better assess and develop the co-op curriculum. Several theoretica...

  16. International Co-operation between Firms on Innovation and R&D: Empirical Evidence from Argentina and Spain

    Directory of Open Access Journals (Sweden)

    Mónica Edwards-Schachter

    2011-09-01

    Full Text Available This paper examines co-operative innovation and Research and Development (R&D behaviour between Argentine and Spanish firms. Based on theoretical perspectives from the literature, we present empirical evidence obtained from 104 firms of patterns of cooperation in several processes and out-puts, highlighting firm characteristics, the motives of the collaborating parties, types of partners, R&D and innovation activities, leadership, and obstacles to cooperation. Our results reveal that the determinants of success differ considerably among countries depending on the sector, the firm specific characteristics and funding.These differences have important implications for public policy and instruments to support R&D and innovation activities.

  17. European tendencies and co-operation in the field of ITS systems - national achievements and challenges in Hungary

    Science.gov (United States)

    Lindenbach, Ágnes

    2016-06-01

    The article presents the role of intelligent transport systems/services related to the implementation of the essential European and Hungarian transport policy objectives. The `ITS Directive' will provide a framework for the tasks/works to be performed in the forthcoming years within the priority areas of ITS. The European Commission published regulations / specifications for the priority actions in the form of delegated acts defining the tasks/responsibilities of Member States. Regional/European co-operation for Hungary started after the EU-accession of the country. Hungary was an active partner within the European CONNECT and EasyWay projects, currently Hungary is a member of the CROCODILE consortium.

  18. Planning assumptions and implementing strategies for co-operative print storage initiatives

    Directory of Open Access Journals (Sweden)

    Mark Sandler

    2012-11-01

    Full Text Available This article recounts some of the major decision points addressed by the library directors on the Committee on Institutional Cooperation (CIC in their efforts to establish a shared print repository for journal back-files widely held across CIC libraries. In 2011, the directors committed to co-invest in a centralized strategy to aggregate 250,000 volumes at Indiana University (IU, with potential for the project to expand over time to address other library formats (i.e. monographs and encompass other storage host-sites. A focus of the article is an assessment of the costs of such projects, and the potential return on the investments being made by the CIC libraries.

  19. Storage Resource Managers Recent International Experience on Requirements and Multiple Co-Operating Implementations

    CERN Document Server

    Abadie, Lana; Baud, Jean-Philippe; Corso, Ezio; Crawford, Matt; De Witt, Shaun; Donno, Flavia; Forti, Alberto; Fuhrmann, Patrick; Grosdidier, Gilbert; Gu, Junmin; Jensen, Jens; Lemaitre, Sophie; Litmaath, Maarten; Litvinsev, Dmitry; Lo Presti, Giuseppe; Magnoni, Luca; Mkrtchan, Tigran; Moibenko, Alexander; Natarajan, Vijaya; Oleynik, Gene; Perelmutov, Timur; Petravick, Don; Shoshani, Arie; Sim, Alex; Sponza, Massimo; Zappi, Riccardo; CERN. Geneva. IT Department

    2007-01-01

    Storage management is one of the most important enabling technologies for large-scale scientific investigations. Having to deal with multiple heterogeneous storage and file systems is one of the major bottlenecks in managing, replicating, and accessing files in distributed environments. Storage Resource Managers (SRMs), named after their web services control protocol, provide the technology needed to manage the rapidly growing distributed data volumes, as a result of faster and larger computational facilities. SRMs are Grid storage services providing interfaces to storage resources, as well as advanced functionality such as dynamic space allocation and file management on shared storage systems. They call on transport services to bring files into their space transparently and provide effective sharing of files. SRMs are based on a common specification that emerged over time and evolved into an international collaboration. This approach of an open specification that can be used by various institutions to adapt ...

  20. Evaluation of potential internal target volume of liver tumors using cine-MRI.

    Science.gov (United States)

    Akino, Yuichi; Oh, Ryoong-Jin; Masai, Norihisa; Shiomi, Hiroya; Inoue, Toshihiko

    2014-11-01

    Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas-Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV Potential). The concordance between ITV Potential and ITV estimated with 4DCT (ITV 4DCT) was evaluated using the Dice's similarity coefficient (DSC). The distance between blood vessel positions

  1. Evaluation of potential internal target volume of liver tumors using cine-MRI

    Energy Technology Data Exchange (ETDEWEB)

    Akino, Yuichi, E-mail: akino@radonc.med.osaka-u.ac.jp [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka 5650871, Japan and Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan); Oh, Ryoong-Jin; Masai, Norihisa; Shiomi, Hiroya; Inoue, Toshihiko [Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan)

    2014-11-01

    Purpose: Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. Methods: The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas–Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV {sub Potential}). The concordance between ITV {sub Potential} and ITV estimated with 4DCT (ITV {sub 4DCT}) was evaluated using the Dice’s similarity coefficient (DSC). Results

  2. Human factors evaluation of teletherapy: Function and task analysis. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Kaye, R.D.; Henriksen, K.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    As a treatment methodology, teletherapy selectively destroys cancerous and other tissue by exposure to an external beam of ionizing radiation. Sources of radiation are either a radioactive isotope, typically Cobalt-60 (Co-60), or a linear accelerator. Records maintained by the NRC have identified instances of teletherapy misadministration where the delivered radiation dose has differed from the radiation prescription (e.g., instances where fractions were delivered to the wrong patient, to the wrong body part, or were too great or too little with respect to the defined treatment volume). Both human error and machine malfunction have led to misadministrations. Effective and safe treatment requires a concern for precision and consistency of human-human and human-machine interactions throughout the course of therapy. The present study is the first part of a series of human factors evaluations for identifying the root causes that lead to human error in the teletherapy environment. The human factors evaluations included: (1) a function and task analysis of teletherapy activities, (2) an evaluation of the human-system interfaces, (3) an evaluation of procedures used by teletherapy staff, (4) an evaluation of the training and qualifications of treatment staff (excluding the oncologists), (5) an evaluation of organizational practices and policies, and (6) an identification of problems and alternative approaches for NRC and industry attention. The present report addresses the function and task analysis of teletherapy activities and provides the foundation for the conduct of the subsequent evaluations. The report includes sections on background, methodology, a description of the function and task analysis, and use of the task analysis findings for the subsequent tasks. The function and task analysis data base also is included.

  3. OTEC modular experiment cold water pipe concept evaluation. Volume III. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    1979-04-01

    The Cold Water Pipe System Design Study was undertaken to evaluate the diverse CWP concepts, recommend the most viable alternatives for a 1984 deployment of the 10 to 40 MWe MEP, and carry out preliminary designs of three concepts. The concept evaluation phase reported involved a systems analysis of design alternatives in the broad categories of rigid walled (with hinges), compliant walled, stockade and bottom mounted buoyant. Quantitative evaluations were made of concept performance, availability, deployment schedule, technical feasibility and cost. CWP concepts were analyzed to determine if they met or could be made to meet established system requirements and could be deployed by 1984. Fabrication, construction and installation plans were developed for successful concepts, and costs were determined in a WBS format. Evaluations were performed on the basis of technical and cost risk. This volume includes the following appendices: (A) materials and associated design criteria; (B) summary of results of dynamic flow and transportation analysis; (C) CWP sizing analysis; (D) CWP thermal performance; and (E) investigation of the APL/ABAM CWP design. (WHK)

  4. A dose-volume-based tool for evaluating and ranking IMRT treatment plans.

    Science.gov (United States)

    Miften, Moyed M; Das, Shiva K; Su, Min; Marks, Lawrence B

    2004-01-01

    External beam radiotherapy is commonly used for patients with cancer. While tumor shrinkage and palliation are frequently achieved, local control and cure remain elusive for many cancers. With regard to local control, the fundamental problem is that radiotherapy-induced normal tissue injury limits the dose that can be delivered to the tumor. While intensity-modulated radiation therapy (IMRT) allows for the delivery of higher tumor doses and the sparing of proximal critical structures, multiple competing plans can be generated based on dosimetric and/or biological constraints that need to be considered/compared. In this work, an IMRT treatment plan evaluation and ranking tool, based on dosimetric criteria, is presented. The treatment plan with the highest uncomplicated target conformity index (TCI+) is ranked at the top. The TCI+ is a dose-volume-based index that considers both a target conformity index (TCI) and a normal tissue-sparing index (NTSI). TCI+ is designed to assist in the process of judging the merit of a clinical treatment plan. To demonstrate the utility of this tool, several competing lung and prostate IMRT treatment plans are compared. Results show that the plan with the highest TCI+ values accomplished the competing goals of tumor coverage and critical structures sparing best, among rival treatment plans for both treatment sites. The study demonstrates, first, that dose-volume-based indices, which summarize complex dose distributions through a single index, can be used to automatically select the optimal plan among competing plans, and second, that this dose-volume-based index may be appropriate for ranking IMRT dose distributions.

  5. Dose evaluation of organs at risk (OAR) cervical cancer using dose volume histogram (DVH) on brachytherapy

    Science.gov (United States)

    Arif Wibowo, R.; Haris, Bambang; Inganatul Islamiyah, dan

    2017-05-01

    Brachytherapy is one way to cure cervical cancer. It works by placing a radioactive source near the tumor. However, there are some healthy tissues or organs at risk (OAR) such as bladder and rectum which received radiation also. This study aims to evaluate the radiation dose of the bladder and rectum. There were 12 total radiation dose data of the bladder and rectum obtained from patients’ brachytherapy. The dose of cervix for all patients was 6 Gy. Two-dimensional calculation of the radiation dose was based on the International Commission on Radiation Units and Measurements (ICRU) points or called DICRU while the 3-dimensional calculation derived from Dose Volume Histogram (DVH) on a volume of 2 cc (D2cc). The radiation dose of bladder and rectum from both methods were analysed using independent t test. The mean DICRU of bladder was 4.33730 Gy and its D2cc was4.78090 Gy. DICRU and D2cc bladder did not differ significantly (p = 0.144). The mean DICRU of rectum was 3.57980 Gy and 4.58670 Gy for D2cc. The mean DICRU of rectum differed significantly from D2cc of rectum (p = 0.000). The three-dimensional method radiation dose of the bladder and rectum was higher than the two-dimensional method with ratios 1.10227 for bladder and 1.28127 for rectum. The radiation dose of the bladder and rectum was still below the tolerance dose. Two-dimensional calculation of the bladder and rectum dose was lower than three-dimension which was more accurate due to its calculation at the whole volume of the organs.

  6. Importance of evaluation of uncertainties on the measurement of natural gas and petroleum volumes; Importancia da avaliacao das incertezas na medicao dos volumes de petroleo e gas natural

    Energy Technology Data Exchange (ETDEWEB)

    Silva Filho, Jose Alberto Pinheiro da; Oliveira, Thiago Barra Vidal de; Mata, Josaphat Dias da [PETROBRAS, Rio de Janeiro, RJ (Brazil)], Emails: jose.pinheiro@petrobras.com.br, thiagovidal@petrobras.com.br, josaphat@petrobras.com.br; Val, Luiz Gustavo do [Instituto de Qualidade e Metrologia (IQM), Rio de Janeiro, RJ (Brazil)], E-mail: gdoval.iqm@petrobras.com.br

    2009-07-01

    The measurement is considered as the 'cash register' of the enterprises, increasing the accuracy and the exigence at each step when come close to the delivery points, where the 0.1 % of differences are discussed. The work presents the approach used in the evaluation of measurement uncertainties in the volumes obtained of petroleum and natural gas at the processes of production in Brazil, and in the international level as well.

  7. Y-12 Plant remedial action Technology Logic Diagram: Volume 3, Technology evaluation data sheets: Part A, Remedial action

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    The Y-12 Plant Remedial Action Technology Logic Diagram (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) problems at the Y-12 Plant to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to remedial action (RA) activities. The TLD consists of three volumes. Volume 1 contains an overview of the TLD, an explanation of the program-specific responsibilities, a review of identified technologies, and the rankings of remedial technologies. Volume 2 contains the logic linkages among environmental management goals, environmental problems and the various technologies that have the potential to solve these problems. Volume 3 contains the TLD data sheets. This report is Part A of Volume 3 and contains the Remedial Action section.

  8. Y-12 Plant remedial action Technology Logic Diagram: Volume 3, Technology evaluation data sheets: Part B, Characterization; robotics/automation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-09-01

    The Y-12 Plant Remedial Action Technology Logic Diagram (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) problems at the Y-12 Plant to potential technologies that can remediate theses problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to remedial action (RA) activities. The TLD consists of three volumes. Volume 1 contains an overview of the TLD, an explanation of the program-specific responsibilities, a review of identified technologies, and the rankings of remedial technologies. Volume 2 contains the logic linkages among environmental management goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 3 contains the TLD data sheets. This report is Part B of Volume 3 and contains the Characterization and Robotics/Automation sections.

  9. Information transfer to out-of-hours co-operatives: a survey of general practitioners' views in relation to palliative patients.

    LENUS (Irish Health Repository)

    Kiely, Fiona

    2013-12-01

    In Ireland, weekend and night medical cover for community based patients is largely provided by general practice co-operatives. Doctors working in this service do not have direct access to patients\\' medical records which challenges continuity of care.

  10. Active and inactive enhancers co-operate to exert localized and long-range control of gene regulation

    Science.gov (United States)

    Proudhon, Charlotte; Snetkova, Valentina; Raviram, Ramya; Lobry, Camille; Badri, Sana; Jiang, Tingting; Hao, Bingtao; Trimarchi, Thomas; Kluger, Yuval; Aifantis, Iannis; Bonneau, Richard; Skok, Jane A

    2016-01-01

    V(D)J recombination relies on the presence of proximal enhancers that activate the antigen receptor (AgR) loci in a lineage and stage specific manner. Unexpectedly we find that both active and inactive AgR enhancers co-operate to disseminate their effects in a localized and long-range manner. Here we demonstrate the importance of short-range contacts between active enhancers that constitute an Igk super-enhancer in B cells. Deletion of one element reduces the interaction frequency between other enhancers in the hub, which compromises the transcriptional output of each component. We further establish that in T cells long-range contact and co-operation between the inactive Igk enhancer, MiEκ and the active Tcrb enhancer, Eβ, alters enrichment of CBFβ binding in a manner that impacts Tcrb recombination. These findings underline the complexities of enhancer regulation and point to a role for localized and long-range enhancer-sharing between active and inactive elements in lineage and stage specific control. PMID:27239026

  11. Evaluation of the impact of viscosity, injection volume, and injection flow rate on subcutaneous injection tolerance

    Directory of Open Access Journals (Sweden)

    Berteau C

    2015-11-01

    Full Text Available Cecile Berteau,1 Orchidée Filipe-Santos,1 Tao Wang,2 Humberto E Rojas,2 Corinne Granger,1 Florence Schwarzenbach1 1Becton-Dickinson Medical Pharmaceutical Systems, Le Pont de Claix, France; 2Eli Lilly and Company, Indianapolis, IN, USA Aim: The primary objective of this study was to evaluate the impact of fluid injection viscosity in combination with different injection volumes and flow rates on subcutaneous (SC injection pain tolerance. Methods: The study was a single-center, comparative, randomized, crossover, Phase I study in 24 healthy adults. Each participant received six injections in the abdomen area of either a 2 or 3 mL placebo solution, with three different fluid viscosities (1, 8–10, and 15–20 cP combined with two different injection flow rates (0.02 and 0.3 mL/s. All injections were performed with 50 mL syringes and 27G, 6 mm needles. Perceived injection pain was assessed using a 100 mm visual analog scale (VAS (0 mm/no pain, 100 mm/extreme pain. The location and depth of the injected fluid was assessed through 2D ultrasound echography images. Results: Viscosity levels had significant impact on perceived injection pain (P=0.0003. Specifically, less pain was associated with high viscosity (VAS =12.6 mm than medium (VAS =16.6 mm or low (VAS =22.1 mm viscosities, with a significant difference between high and low viscosities (P=0.0002. Target injection volume of 2 or 3 mL was demonstrated to have no significant impact on perceived injection pain (P=0.89. Slow (0.02 mL/s or fast (0.30 mL/s injection rates also showed no significant impact on perceived pain during SC injection (P=0.79. In 92% of injections, the injected fluid was located exclusively in SC tissue whereas the remaining injected fluids were found located in SC and/or intradermal layers. Conclusion: The results of this study suggest that solutions of up to 3 mL and up to 15–20 cP injected into the abdomen within 10 seconds are well tolerated without pain. High

  12. 1 November 2012 - Signature of the Co-operation Agreement between the Administrative Department of Science, Technology and Innovation (COLCIENCIAS) of Colombia and the European Organization for Nuclear Research (CERN) concerning Scientific and Technical Co-operation in High-Energy Physics and related technologies by CERN Director-General R. Heuer, witnessed by Ambassador of Colombia to Switzerland C. Turbay Quintero.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    1 November 2012 - Signature of the Co-operation Agreement between the Administrative Department of Science, Technology and Innovation (COLCIENCIAS) of Colombia and the European Organization for Nuclear Research (CERN) concerning Scientific and Technical Co-operation in High-Energy Physics and related technologies by CERN Director-General R. Heuer, witnessed by Ambassador of Colombia to Switzerland C. Turbay Quintero.

  13. 3 July 2007 - Ambassador A. Navarro Llanos, Permanent Representative of the Republic of Bolivia to the United Nations Office and other international organisations in Geneva signing a Co-operation Agreement concerning Scientific and Technical Co-operation in High-Energy Physics with CERN Director General R. Aymar.

    CERN Multimedia

    Maximilien Brice

    2007-01-01

    3 July 2007 - Ambassador A. Navarro Llanos, Permanent Representative of the Republic of Bolivia to the United Nations Office and other international organisations in Geneva signing a Co-operation Agreement concerning Scientific and Technical Co-operation in High-Energy Physics with CERN Director General R. Aymar.

  14. Committee to evaluate Sandia`s risk expertise: Final report. Volume 1: Presentations

    Energy Technology Data Exchange (ETDEWEB)

    Dudley, E.C.

    1998-05-01

    On July 1--2, 1997, Sandia National Laboratories hosted the External Committee to Evaluate Sandia`s Risk Expertise. Under the auspices of SIISRS (Sandia`s International Institute for Systematic Risk Studies), Sandia assembled a blue-ribbon panel of experts in the field of risk management to assess their risk programs labs-wide. Panelists were chosen not only for their own expertise, but also for their ability to add balance to the panel as a whole. Presentations were made to the committee on the risk activities at Sandia. In addition, a tour of Sandia`s research and development programs in support of the US Nuclear Regulatory Commission was arranged. The panel attended a poster session featuring eight presentations and demonstrations for selected projects. Overviews and viewgraphs from the presentations are included in Volume 1 of this report. Presentations are related to weapons, nuclear power plants, transportation systems, architectural surety, environmental programs, and information systems.

  15. Stereological estimates of nuclear volume and other quantitative variables in supratentorial brain tumors. Practical technique and use in prognostic evaluation

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Braendgaard, H; Chistiansen, A O

    1991-01-01

    the practical technique. The continuous variables were correlated with the subjective, qualitative WHO classification of brain tumors, and the prognostic value of the parameters was assessed. Well differentiated astrocytomas (n = 14) had smaller estimates of the volume-weighted mean nuclear volume and mean...... was significantly increased in glioblastomas (2p = 0.01). Three-dimensional, shape-independent estimates of macroscopical tumor volume were not different in anaplastic astrocytomas and glioblastomas (2p = 0.39). Histological type of tumor and mitotic index were of significant prognostic value (2p = 8.2.10(-6) and 2...... techniques in the prognostic evaluation of primary brain tumors....

  16. Petrophysical studies of north American carbonate rock samples and evaluation of pore-volume compressibility models

    Science.gov (United States)

    da Silva, Gilberto Peixoto; Franco, Daniel R.; Stael, Giovanni C.; da Costa de Oliveira Lima, Maira; Sant'Anna Martins, Ricardo; de Moraes França, Olívia; Azeredo, Rodrigo B. V.

    2015-12-01

    In this work, we evaluate two pore volume compressibility models that are currently discussed in the literature (Horne, 1990; Jalalh, 2006b). Five groups of carbonate rock samples from the three following sedimentary basins in North America that are known for their association with hydrocarbon deposits were selected for this study: (i) the Guelph Formation of the Michigan Basin (Middle Silurian); (ii) the Edwards Formation of the Central Texas Platform (Middle Cretaceous); and (iii) the Burlington-Keokuk Formation of the Mississippian System (Lower Mississippian). In addition to the evaluation of the compressibility model, a petrophysical evaluation of these rock samples was conducted. Additional characterizations, such as grain density, the effective porosity, absolute grain permeability, thin section petrography, MICP and NMR, were performed to complement constant pore-pressure compressibility tests. Although both models presented an overall good representation of the compressibility behavior of the studied carbonate rocks, even when considering their broad porosity range (~ 2-38%), the model proposed by Jalalh (2006b) performed better with a confidence level of 95% and a prediction interval of 68%.

  17. Co-operation Agreement between the Ministry of Science, Technology and Environment of the Republic of Cuba (CITMA) and CERN concerning The Further Development of Scientific and Technical Co-operation

    CERN Document Server

    2003-01-01

    In the framework of the CERN collaboration with Latin America, co-operation agreements have been established with Argentina, Brazil, Colombia, Chile, Mexico and Peru. They have made possible a growing participation by Latin American particle physicists in the CERN programme, which has important potential for the future. The Cuban particle physics community is highly motivated and relatively advanced, both scientifically and technologically, since many of its members have been trained in installations of the former Soviet Union, many of which now participate in CERN's cooperation with Russia. In addition, Cuba has a good number of experienced computer scientists. A group from the Cuban Institute CEADEN (Centro de Aplicaciones Tecnológicas y Desarollo Nuclear) has recently been accepted unanimously into the ALICE collaboration, with agreed contributions to off-line software and Grid middlewave. Additional Cuban contributions to show controls, data acquisition and testing electronics for the Silicon drift decte...

  18. Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion

    Directory of Open Access Journals (Sweden)

    RUI R.F. FERREIRA

    2015-03-01

    Full Text Available Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV. No previous studies evaluated sedated donors.Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent.Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in non-sedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered.Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.

  19. Evaluation of single right atrial volume and function with magnetic resonance imaging in children with hypoplastic left heart

    Energy Technology Data Exchange (ETDEWEB)

    Vijarnsorn, Chodchanok [University of Alberta, Faculty of Medicine and Dentistry, Stollery Children' s Hospital, Edmonton, AB (Canada); Mahidol University, Siriraj Hospital, Bangkok (Thailand); Myers, Kimberley; Patton, David J. [Alberta Children' s Hospital, Section of Pediatric Cardiology, Department of Pediatrics, Department of Pediatrics, Calgary, AB (Canada); Noga, Michelle; Crawley, Cinzia; Tham, Edythe [University of Alberta, Faculty of Medicine and Dentistry, Stollery Children' s Hospital, Edmonton, AB (Canada)

    2016-06-15

    Standardized methods to evaluate atrial properties in single ventricles are lacking. To determine the feasibility of quantifying right atrial volumes and function in hypoplastic left heart using MRI. We studied 15 infants with hypoplastic left heart prior to Glenn surgery (mean age 4.2 months [standard deviation 0.3]) who underwent cardiac MRI with evaluation of atrial volumes and emptying fraction using monoplane two-chamber, monoplane four-chamber, and biplane methods, all of which were compared to the atrial short-axial oblique stack method. We compared atrial end-diastolic volume, end-systolic volume and emptying fraction among these methods. We analyzed reproducibility of the methods using Bland-Altman plots. Both four-chamber and biplane methods showed high correlations for atrial end-diastolic volume (r = 0.7 and r = 0.8, respectively; P < 0.01) and end-systolic volume (r = 0.8 and r = 0.9, respectively; P < 0.01) with small mean differences (-0.2 ± 2.9 standard deviation [SD] ml and -0.8 ± 1.6 ml, respectively, for atrial end-diastolic volume and -0.8 ± 1.5 ml and -0.9 ± 0.9 ml, respectively, for atrial end-systolic volume). The short-axial oblique method was the most reproducible, followed by the four-chamber method. MRI assessment of atrial volume and function is feasible in hypoplastic left heart and might provide further insight into single-ventricle mechanics. (orig.)

  20. Office for Analysis and Evaluation of Operational Data. 1992 annual report: Nonreactors: Volume 7, No. 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-10-01

    The annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) is devoted to the activities performed during 1992. The report is published in two separate parts. NUREG-1272, Vol. 7, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about the trends of some key performance measures. The report also includes the principal findings and issues identified in AEOD studies over the past year and summarizes information from such sources as licensee event reports, diagnostic evaluations, and reports to the NRC`s Operations Center. NUREG-1272, Vol. 7, No. 2, covers nonreactors and presents a review of the events and concerns during 1992 associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Both reports also contain a discussion of the Incident Investigation Team program and summarize both the Incident Investigation Team and Augmented Inspection Team reports. Each volume contains a list of the AEOD reports issued for 1981--1992.

  1. Export Potential of the Russian Automobile Industry: Evaluation of Directions and Volumes

    Directory of Open Access Journals (Sweden)

    Aleksandr Borisovich Zuev

    2016-12-01

    Full Text Available Automobile industry is among the priority industries in Russia from the perspective of non-oil export development. It appears to be very timely to evaluate its export potential due to a significant contraction of the Russian car market and excessive idle capacity of the industry. The paper is based on international Export Decision Support Models and on the analysis of a vast amount of international economic indicators. It aims to identify the most attractive countries for Russia’s passenger automobiles and trucks exports and to evaluate the potential increases in absolute physical volumes of export growth. The three-stage procedure eliminates unattractive markets. The first stage filter removes from consideration countries with high political and commercial risk and with low macroeconomic size. The second filter is for export opportunity assessment. And the third filter describes the level of availability from the point of view of logistics costs and trade barrier. 17 countries which fail the selection were enrolled in the list due to potentially promising markets for Russian products. Then the total export potential was calculated on the basis of Russian potential share in a particular country taking into account index trade availability and the average price of a car imported to each country. As a result, top-5 countries for Russian cars and trucks exports are found, and aggregate export potential is estimated at 194 thousand passenger vehicles and 30 thousand trucks per year for the next few years.

  2. Evaluation of the impact of viscosity, injection volume, and injection flow rate on subcutaneous injection tolerance

    Science.gov (United States)

    Berteau, Cecile; Filipe-Santos, Orchidée; Wang, Tao; Rojas, Humberto E; Granger, Corinne; Schwarzenbach, Florence

    2015-01-01

    Aim The primary objective of this study was to evaluate the impact of fluid injection viscosity in combination with different injection volumes and flow rates on subcutaneous (SC) injection pain tolerance. Methods The study was a single-center, comparative, randomized, crossover, Phase I study in 24 healthy adults. Each participant received six injections in the abdomen area of either a 2 or 3 mL placebo solution, with three different fluid viscosities (1, 8–10, and 15–20 cP) combined with two different injection flow rates (0.02 and 0.3 mL/s). All injections were performed with 50 mL syringes and 27G, 6 mm needles. Perceived injection pain was assessed using a 100 mm visual analog scale (VAS) (0 mm/no pain, 100 mm/extreme pain). The location and depth of the injected fluid was assessed through 2D ultrasound echography images. Results Viscosity levels had significant impact on perceived injection pain (P=0.0003). Specifically, less pain was associated with high viscosity (VAS =12.6 mm) than medium (VAS =16.6 mm) or low (VAS =22.1 mm) viscosities, with a significant difference between high and low viscosities (P=0.0002). Target injection volume of 2 or 3 mL was demonstrated to have no significant impact on perceived injection pain (P=0.89). Slow (0.02 mL/s) or fast (0.30 mL/s) injection rates also showed no significant impact on perceived pain during SC injection (P=0.79). In 92% of injections, the injected fluid was located exclusively in SC tissue whereas the remaining injected fluids were found located in SC and/or intradermal layers. Conclusion The results of this study suggest that solutions of up to 3 mL and up to 15–20 cP injected into the abdomen within 10 seconds are well tolerated without pain. High viscosity injections were shown to be the most tolerated, whereas injection volume and flow rates did not impact perceived pain. PMID:26635489

  3. Strategies to evaluate the impact of rectal volume on prostate motion during three-dimensional conformal radiotherapy for prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Poli, Ana Paula Diniz Fortuna, E-mail: anapaulafortuna@yahoo.com.br [Universidade Estadual de Campinas (CAISM/UNICAMP), Campinas, SP (Brazil). Centro de Atencao Integrada a Saude da Mulher. Divisao de Radioterapia; Dias, Rodrigo Souza; Giordani, Adelmo Jose; Segreto, Helena Regina Comodo; Segreto, Roberto Araujo [Universidade Federal de Sao Paulo (EPM/UNIFESP), Sao Paulo, SP (Brazil). Escola Paulista de Medicina. Divisao de Radioterapia

    2016-01-15

    Objective: To evaluate the rectal volume influence on prostate motion during three-dimensional conformal radiotherapy (3D-CRT) for prostate cancer. Materials and Methods: Fifty-one patients with prostate cancer underwent a series of three computed tomography scans including an initial planning scan and two subsequent scans during 3D-CRT. The organs of interest were outlined. The prostate contour was compared with the initial CT images considering the anterior, posterior, superior, inferior and lateral edges of the organ. Variations in the anterior limits and volume of the rectum were assessed and correlated with prostate motion in the anteroposterior direction. Results: The maximum range of prostate motion was observed in the superoinferior direction, followed by the anteroposterior direction. A significant correlation was observed between prostate motion and rectal volume variation (p = 0.037). A baseline rectal volume superior to 70 cm{sup 3} had a significant influence on the prostate motion in the anteroposterior direction (p = 0.045). Conclusion: The present study showed a significant interfraction motion of the prostate during 3D-CRT with greatest variations in the superoinferior and anteroposterior directions, and that a large rectal volume influences the prostate motion with a cutoff value of 70 cm{sup 3}. Therefore, the treatment of patients with a rectal volume > 70 cm{sup 3} should be re-planned with appropriate rectal preparation. Keywords: Rectal volume; Prostate cancer; Three-dimensional conformal radiotherapy. (author)

  4. Gas Reactor International Cooperative program. Pebble bed reactor plant: screening evaluation. Volume 2. Conceptual balance of plant design

    Energy Technology Data Exchange (ETDEWEB)

    1979-11-01

    This report consists of three volumes which describe the design concepts and screening evaluation for a 3000 MW(t) Pebble Bed Reactor Multiplex Plant (PBR-MX). The Multiplex plant produces both electricity and transportable chemical energy via the thermochemical pipeline (TCP). The evaluation was limited to a direct cycle plant which has the steam generators and steam reformers in the primary circuit. This volume describes the conceptual balance-of-plant (BOP) design and was prepared by United Engineers and Constructors, Inc. of Philadelphia, Pennsylvania. The major emphasis of the BOP study was a preliminary design of an overall plant to provide a basis for future studies.

  5. The Relationship between journalists and PR practitioners in Romania – Somewhere in between co-operation and conflict

    Directory of Open Access Journals (Sweden)

    Cristina COMAN

    2009-01-01

    Full Text Available One constant idea emerges from all of the studies regarding the relationship between journalists and PR practitioners: this relationship is a complex and ambiguous one. It is quite obvious that both participants aim at holding control over the production and distribution of information; despite this aim, it is certain that none of the two can develop a monopoly over such a process. The inter-dependency between the actors involved in this game is based on the interest in mutual co-operation showed by each of the participants. This very study stands for the fact that by means of the values they referred to, the Romanian journalists and PR professionals express attitudes that are similar to those of their colleagues from other countries where these two professions have a longer tradition behind.

  6. Going the extra mile - creating a co-operative model for supporting patient and public involvement in research.

    Science.gov (United States)

    Horobin, Adele

    2016-01-01

    In 2014, the Chief Medical Officer and Director General of Research and Development commissioned a review of patient and public involvement in the National Institute for Health Research. The report on this review, entitled 'Going the Extra Mile' was published in March, 2015. It described the bold goal of expecting all people using health and social care, and increasing numbers of the public, to be aware of and choosing to be involved in research. This requires more effort to build public awareness of research and better support for the public and researchers to do patient and public involvement in research. The author has created a new way of providing support for patient and public involvement based on co-operation between organisations. Termed 'share-banking', this model pools limited resources across organisations to deliver a regional programme of support activities for patient and public involvement over the long term. This includes helping organisations to share and learn from each other to avoid 're-inventing wheels' (where separate organisations each develop the same thing from the beginning). The 'Going the Extra Mile' report recommends that local organisations should work together to deliver public involvement activities across a region. 'Share-banking' should help fulfil this recommendation. The 'Going the Extra Mile' final report opened with the ambition to increase the public's awareness, participation and involvement in research. It stated the need for public and researchers to be better supported to do public involvement. A new co-operative model, termed 'share-banking', has been developed whereby organisations pool limited resources to create and sustain support for patient and public involvement in research. This should fulfil the 'Going the Extra Mile' report's recommendation to take a collaborative, cross-organisational and regional approach to public involvement.

  7. dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes

    Science.gov (United States)

    Korenjak, Michael; Kwon, Eunjeong; Morris, Robert T.; Anderssen, Endre; Amzallag, Arnaud; Ramaswamy, Sridhar; Dyson, Nicholas J.

    2014-01-01

    dREAM complexes represent the predominant form of E2F/RBF repressor complexes in Drosophila. dREAM associates with thousands of sites in the fly genome but its mechanism of action is unknown. To understand the genomic context in which dREAM acts we examined the distribution and localization of Drosophila E2F and dREAM proteins. Here we report a striking and unexpected overlap between dE2F2/dREAM sites and binding sites for the insulator-binding proteins CP190 and Beaf-32. Genetic assays show that these components functionally co-operate and chromatin immunoprecipitation experiments on mutant animals demonstrate that dE2F2 is important for association of CP190 with chromatin. dE2F2/dREAM binding sites are enriched at divergently transcribed genes, and the majority of genes upregulated by dE2F2 depletion represent the repressed half of a differentially expressed, divergently transcribed pair of genes. Analysis of mutant animals confirms that dREAM and CP190 are similarly required for transcriptional integrity at these gene pairs and suggest that dREAM functions in concert with CP190 to establish boundaries between repressed/activated genes. Consistent with the idea that dREAM co-operates with insulator-binding proteins, genomic regions bound by dREAM possess enhancer-blocking activity that depends on multiple dREAM components. These findings suggest that dREAM functions in the organization of transcriptional domains. PMID:25053843

  8. Oak Ridge National Laboratory Technology Logic Diagram. Volume 3, Technology evaluation data sheets: Part A, Characterization, Decontamination

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Oak Ridge National Laboratory Technology Logic Diagram (TLD) was developed to provide a decision support tool that relates environmental restoration (ER) and waste management (WM) problems at Oak Ridge National Laboratory (ORNL) to potential technologies that can remediate these problems. The TLD consists of three fundamentally separate volumes: Vol. 1, Technology Evaluation; Vol. 2, Technology Logic Diagram; and Vol. 3, Technology Evaluation Data Sheets. Part A of Vols. 1 and 2 focuses on RA. Part B of Vols. 1 and 2 focuses on the D&D of contaminated facilities. Part C of Vols. 1 and 2 focuses on WM. Each part of Vol. 1 contains an overview of the TLD, an explanation of the problems facing the volume-specific program, a review of identified technologies, and rankings of technologies applicable to the site. Volume 2 (Pts. A, B, and C) contains the logic linkages among EM goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 3 (Pts. A, B,and C) contains the TLD data sheets. This volume provides the technology evaluation data sheets (TEDS) for ER/WM activities (D&D, RA, and WM) that are referenced by a TEDS code number in Vol. 2 of the TLD. Each of these sheets represents a single logic trace across the TLD. These sheets contain more detail than is given for the technologies in Vol. 2. The data sheets are arranged alphanumerically by the TEDS code number in the upper right comer of each sheet.

  9. Evaluation of gallbladder volume and contraction index with three-dimensional ultrasonography in healthy dogs.

    Science.gov (United States)

    Rahmani, Vahideh; Molazem, Mohammad; Jamshidi, Shahram; Vali, Yasamin; Hanifeh, Mohsen

    2015-09-01

    Three-dimensional (3D) ultrasonography has been shown to be an accurate and appropriate tool for measurement of gallbladder volume in humans. Therefore, we applied this novel technique for the first time to study fasting and postprandial gallbladder volume in 10 healthy dogs and compared the results with those of 2-dimensional (2D) ultrasonography. Fasting gallbladder volumes determined by 3D ultrasonography were significantly higher than corresponding volumes determined by 2D ultrasonography (Pultrasonography (Pultrasonography showed no significant difference (P=0.189). The Gallbladder contraction index was higher in 3D ultrasonography than 2D ultrasonography; however, it did not reach statistical significance (P=0.25). In conclusion, 3D ultrasonography was able to measure gallbladder volume in healthy dogs in this study. It is suggested that 3D ultrasonography can be used to accurately estimate gallbladder volume and contractility.

  10. When a business isn’t a business: law and the political in the history of the United Kingdom’s co-operative movement

    Directory of Open Access Journals (Sweden)

    Tara Mulqueen

    2012-05-01

    Full Text Available Contemporary efforts to develop and promote co-operatives and the social economy confront a tension in the competing and often conflicting aims to achieve commercial sustainability in a capitalist market while also promoting social transformation. Through a review of the historical experience of institutionalization in the Co-operative Movement in the United Kingdom, this article attempts to generate insights into these tensions. Despite being seen as unpolitical, co-operatives can be understood as political at the level of re-shaping sociality through co-operative practice. Although the similarity between co-operatives and joint-stock companies produces ambiguities within the movement, this does not in itself detract from the co-operative project. It is argued that the codification of co-operatives in law as bodies corporate constitutes the closure of the political aspect of co-operation and reinforces and gives consequence to the misconception of co-operatives as primarily commercial entities. Los esfuerzos por desarrollar y promover las cooperativas y la economía social se enfrentan a un conflicto entre los objetivos contrapuestos de lograr la sostenibilidad comercial en un mercado capitalista, a la vez que se promueve una transformación de la sociedad. Realizando una revisión de la experiencia histórica de la institucionalización del movimiento cooperativista en el Reino Unido, este artículo pretende analizar estas tensiones. A pesar de ser apolíticas, las cooperativas se pueden entender como un elemento político por su intento de reformular la sociedad. Aunque la similitud entre cooperativas y sociedades anónimas produce ambigüedades dentro del movimiento cooperativista, esto no va, por sí mismo, en detrimento del proyecto de cooperación. Se argumenta que, al contemplar en la legislación a las cooperativas como personas jurídicas, se acaba con el aspecto político de las cooperativas. A su vez, esto refuerza y termina con la

  11. Evaluation of stroke volume variation obtained by arterial pulse contour analysis to predict fluid responsiveness intraoperatively.

    Science.gov (United States)

    Lahner, D; Kabon, B; Marschalek, C; Chiari, A; Pestel, G; Kaider, A; Fleischmann, E; Hetz, H

    2009-09-01

    Fluid management guided by oesophageal Doppler monitor has been reported to improve perioperative outcome. Stroke volume variation (SVV) is considered a reliable clinical predictor of fluid responsiveness. Consequently, the aim of the present trial was to evaluate the accuracy of SVV determined by arterial pulse contour (APCO) analysis, using the FloTrac/Vigileo system, to predict fluid responsiveness as measured by the oesophageal Doppler. Patients undergoing major abdominal surgery received intraoperative fluid management guided by oesophageal Doppler monitoring. Fluid boluses of 250 ml each were administered in case of a decrease in corrected flow time (FTc) to 10%. The ability of SVV to predict fluid responsiveness was assessed by calculation of the area under the receiver operating characteristic (ROC) curve. Twenty patients received 67 fluid boluses. Fifty-two of the 67 fluid boluses administered resulted in fluid responsiveness. SVV achieved an area under the ROC curve of 0.512 [confidence interval (CI) 0.32-0.70]. A cut-off point for fluid responsiveness was found for SVV > or =8.5% (sensitivity: 77%; specificity: 43%; positive predictive value: 84%; and negative predictive value: 33%). This prospective, interventional observer-blinded study demonstrates that SVV obtained by APCO, using the FloTrac/Vigileo system, is not a reliable predictor of fluid responsiveness in the setting of major abdominal surgery.

  12. The ADVANCE project: Formal evaluation of the targeted deployment. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The Advanced Driver and Vehicle Advisory Navigation ConcEpt (ADVANCE) was an invehicle advanced traveler information system (ATIS) that operated in the northwest suburbs of Chicago, Illinois. It was designed to provide origin-destination shortest-time route guidance to a vehicle based on (a) an on-board static (fixed) data base of average network link travel times by time of day, combined as available and appropriate with (b) dynamic (real-time) information on traffic conditions provided by radio frequency (RF) communications to and from a traffic information center (TIC). Originally conceived in 1990 as a major project that would have installed 3,000 to 5,000 route guidance units in privately owned vehicles throughout the test area, ADVANCE was restructured in 1995 as a {open_quotes}targeted deployment,{close_quotes} in which approximately 80 vehicles were to be equipped with the guidance units - Mobile Navigation Assistants (MNAs) - to be in full communication with the TIC while driving the ADVANCE test area road system. Volume one consists of the evaluation managers overview report, and several appendices containing test results.

  13. A mathematical model approach quantifying patients' response to changes in mechanical ventilation: evaluation in volume support.

    Science.gov (United States)

    Larraza, S; Dey, N; Karbing, D S; Jensen, J B; Nygaard, M; Winding, R; Rees, S E

    2015-04-01

    This paper presents a mathematical model-approach to describe and quantify patient-response to changes in ventilator support. The approach accounts for changes in metabolism (V̇O2, V̇CO2) and serial dead space (VD), and integrates six physiological models of: pulmonary gas-exchange; acid-base chemistry of blood, and cerebrospinal fluid; chemoreflex respiratory-drive; ventilation; and degree of patients' respiratory muscle-response. The approach was evaluated with data from 12 patients on volume support ventilation mode. The models were tuned to baseline measurements of respiratory gases, ventilation, arterial acid-base status, and metabolism. Clinical measurements and model simulated values were compared at five ventilator support levels. The models were shown to adequately describe data in all patients (χ(2), p > 0.2) accounting for changes in V̇CO2, VD and inadequate respiratory muscle-response. F-ratio tests showed that this approach provides a significantly better (p ventilation. The approach may help predict patients' response to changes in ventilator support at the bedside. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.

  14. Office for Analysis and Evaluation of Operational Data 1996 annual report. Volume 10, Number 1: Reactors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) describes activities conducted during 1996. The report is published in three parts. NUREG-1272, Vol. 10, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about trends of some key performance measures. The report also includes the principal findings and issues identified in AEOD studies over the past year and summarizes information from such sources as licensee event reports and reports to the NRC`s Operations Center. NUREG-1272, Vol. 10, No. 2, covers nuclear materials and presents a review of the events and concerns during 1996 associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Both reports also contain a discussion of the Incident Investigation Team program and summarize both the Incident Investigation Team and Augmented Inspection Team reports. Each volume contains a list of the AEOD reports issued from CY 1980 through 1996. NUREG-1272, Vol. 10, No. 3, covers technical training and presents the activities of the Technical Training Center in support of the NRC`s mission in 1996.

  15. Evaluation of Productivity of Zymotis Solid-State Bioreactor Based on Total Reactor Volume

    Directory of Open Access Journals (Sweden)

    Oscar F. von Meien

    2002-01-01

    Full Text Available In this work a method of analyzing the performance of solid-state fermentation bioreactors is described. The method is used to investigate the optimal value for the spacing between the cooling plates of the Zymotis bioreactor, using simulated fermentation data supplied by a mathematical model. The Zymotis bioreactor has good potential for those solid-state fermentation processes in which the substrate bed must remain static. The current work addresses two design parameters introduced by the presence of the internal heat transfer plates: the width of the heat transfer plate, which is governed by the amount of heat to be removed and the pressure drop of the cooling water, and the spacing between these heat transfer plates. In order to analyze the performance of the bioreactor a productivity term is introduced that takes into account the volume occupied within the bioreactor by the heat transfer plates. As part of this analysis, it is shown that, for logistic growth kinetics, the time at which the biomass reaches 90 % of its maximum possible value is a good estimate of the optimum harvesting time for maximizing productivity. Application of the productivity analysis to the simulated fermentation results suggests that, with typical fast growing fungi ( = 0.324 h–1, the optimal spacing between heat transfer plates is of the order of 6 cm. The general applicability of this approach to evaluate the productivity of solid-state bioreactors is demonstrated.

  16. Impact Study on Driving by Special Populations. Final Report. Volume II: A Guide for the Evaluation of Handicapped Drivers.

    Science.gov (United States)

    Brainin, Paul A.; And Others

    The second of a two-volume report on motor vehicle driving by handicapped persons presents an approach to the evaluation of drivers with 20 specific )edical problems. The guide provides information on symptoms, treatment, guidelines for determining risk levels (risk increasing and risk moderating factors), questions for the applicant, and…

  17. Using a three-dimensional computer assisted stone volume estimates to evaluate extracorporeal shockwave lithotripsy treatment of kidney stones

    DEFF Research Database (Denmark)

    Bigum, Lene Hyldgaard; Ulriksen, Peter Sommer; Omar, Omar Salah

    2016-01-01

    This study describes and evaluates the use of non-contrast enhanced computerized tomography (NCCT) before and after extracorporeal shockwave lithotripsy (SWL). Computer measured stone volume was used as an exact measurement for treatment response. 81 patients received SWL of kidney stones at Herlev...

  18. Dose volume uniformity index: a simple tool for treatment plan evaluation in brachytherapy

    Directory of Open Access Journals (Sweden)

    Ramachandran Prabhakar

    2010-07-01

    Full Text Available Purpose: In radiotherapy treatment planning, dose homogeneity inside the target volume plays a significant role in the final treatment outcome. Especially in brachytherapy where there is a steep dose gradient in the dose distribution inside the target volume, comparing the plans based on the dose homogeneity helps in assessing the high dose volume inside the final treatment plan. In brachytherapy, the dose inhomogeneity inside the target volume depends on many factors such as the type of sources, placement of these radioactive sources, distance between the applicators/implanttubes, dwell time of the source, etc. In this study, a simple index, the dose volume uniformity index (DVUI, has been proposed to study the dose homogeneity inside the target volume. This index gives the total dose volume inhomogeneity inside a given prescription isoline.Material and methods: To demonstrate the proposed DVUI in this study, a single plane implant (breast: 6 catheters, a double plane implant (breast: 9 catheters and a tongue implant (5 catheters were selected. The catheters were reconstructed from the CT image datasets in the Plato treatment planning system. The doses for the single, double and tongue implants were prescribed to the reference dose rate as per the Paris technique. DVUI was computed from the cumulative dose volume histogram.Results: For a volume receiving a uniform dose inside the prescription isoline, the DVUI is 1. Any value of DVUI > 1 shows the presence of a relatively high dose volume inside the prescription isoline. In addition to the concept of DVUI, a simple conformality index, the dose volume conformality index (DVCI, has also been proposed in this study based on the DVUI.Conclusion: The DVUI and the proposed DVCI in this study provide an easy way of comparing the rival plans in brachytherapy.

  19. Strategies to evaluate the impact of rectal volume on prostate motion during three-dimensional conformal radiotherapy for prostate cancer

    Directory of Open Access Journals (Sweden)

    Ana Paula Diniz Fortuna Poli

    2016-02-01

    Full Text Available Abstract Objective: To evaluate the rectal volume influence on prostate motion during three-dimensional conformal radiotherapy (3D-CRT for prostate cancer. Materials and Methods: Fifty-one patients with prostate cancer underwent a series of three computed tomography scans including an initial planning scan and two subsequent scans during 3D-CRT. The organs of interest were outlined. The prostate contour was compared with the initial CT images considering the anterior, posterior, superior, inferior and lateral edges of the organ. Variations in the anterior limits and volume of the rectum were assessed and correlated with prostate motion in the anteroposterior direction. Results: The maximum range of prostate motion was observed in the superoinferior direction, followed by the anteroposterior direction. A significant correlation was observed between prostate motion and rectal volume variation ( p = 0.037. A baseline rectal volume superior to 70 cm3 had a significant influence on the prostate motion in the anteroposterior direction ( p = 0.045. Conclusion: The present study showed a significant interfraction motion of the prostate during 3D-CRT with greatest variations in the superoinferior and anteroposterior directions, and that a large rectal volume influences the prostate motion with a cutoff value of 70 cm3. Therefore, the treatment of patients with a rectal volume > 70 cm3 should be re-planned with appropriate rectal preparation.

  20. Evaluation of oscillation-free fluid-porous interface treatments for segregated finite volume flow solvers

    NARCIS (Netherlands)

    Staniç, M.; Nordlund, M.; Frederix, E.M.A.; Kuczaj, Arkadiusz K.; Geurts, Bernardus J.

    2016-01-01

    The volume-averaged approach to simulate flow in porous media is often used because of its practicality and computational efficiency. Derivation of the volume-averaged porous flow equations introduces additional porous resistance terms to the momentum equation. These porous resistance terms create

  1. An Evaluation of the Nutrition Services for the Elderly. Volume V. Questionnaires.

    Science.gov (United States)

    Kirschner Associates, Inc., Albuquerque, NM.

    This document is part of a five-volume nationwide study of Nutrition Services operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. This volume contains the questionnaires used in the study. Section 1 gives a report overview and acknowledgements. Section…

  2. An Evaluation of the Nutrition Services for the Elderly. Volume IV. Appendices.

    Science.gov (United States)

    Kirschner Associates, Inc., Albuquerque, NM.

    This document is part of a five-volume nationwide study of Nutrition Services operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. This volume contains all technical appendices and is intended as a resource document. The Methodology Appendix is included…

  3. An Evaluation of the Nutrition Services for the Elderly. Volume III. Descriptive Report.

    Science.gov (United States)

    Kirschner Associates, Inc., Albuquerque, NM.

    This document is part of a five-volume nationwide study of Nutrition Services operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. A descriptive report is contained in this volume, which presents non-selective and preliminary analysis of the data base…

  4. Evaluation of postoperative lung volume and perfusion changes by dual-energy computed tomography in patients with lung cancer.

    Science.gov (United States)

    Choe, Jooae; Lee, Sang Min; Chae, Eun Jin; Lee, Sang Min; Kim, Yong-Hee; Kim, Namkug; Seo, Joon Beom

    2017-05-01

    The aim of our study was to retrospectively evaluate postoperative physiologic changes in lung cancer patients using dual-energy CT (DECT), and develop modified methods reflecting postoperative change for predicting pulmonary function. 88 patients (M:F=64:24; mean age, 63.5 years) with lung cancer who underwent DECT and pulmonary function tests before and after operation were included. Volume and iodine values for perfusion of each lobe were quantified. The predicted postoperative FEV1 using the current method was calculated by multiplying the preoperative FEV1 by the fractional contribution of perfusion of the remaining lung. The modified method reflecting postoperative volume change was compared to the current method. Postoperative lung volume showed compensatory increases in the contralateral and remaining ipsilateral lobes, with a significantly greater increase in the ipsilateral lobe than contralateral lobe (21.8%±46.2% vs. 10.0%±20.8%, P=0.031). Perfusion analysis showed blood volume increases in both ipsilateral and contralateral lobes without statistical differences (blood volume ratio difference, 29.2%±26.7 vs. 24.6%±16.5, P=0.368). The performance of the modified method considering postoperative lung volume change was comparable to that of the current method in the development and validation datasets (95% CI, -24.5% to 37.1% vs. -33.3% to 22.2% and -23.6% to 32.0% vs. -31.9% to 16.0%, respectively). Postoperative compensatory increases in lung volume and perfusion occur in different ways. Our modified method incorporating postoperative lung volume changes can be considered a comparable method for prediction of postoperative lung function. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Evaluation of distributed parameters mathematical models applied to grain hydration with volume change

    Science.gov (United States)

    Nicolin, Douglas J.; Jorge, Regina Maria M.; Jorge, Luiz Mario M.

    2015-01-01

    Several studies have taken into account the volume change of foods that undergo hydration or drying. However, the simplest boundary condition at the surface is usually considered to facilitate the solution of variable volume models. This paper presents a model of moisture diffusion in soybean grains that considers the volume change of these grains when absorbing water and also the dependence of diffusivity on moisture content. The boundary condition of equality of diffusive and convective flows on the surface was used and compared with two other approaches commonly found in the literature of grain hydration. This boundary condition was also applied to the case of constant volume of the grains and it was concluded that there are significant differences when the change in volume is taken into account. An analysis of the diffusion coefficients determined as functions of moisture content, temperature, and hydration time is presented for the best model.

  6. Co-operation and conflict under hard and soft contracting regimes: case studies from England and Wales.

    Science.gov (United States)

    Hughes, David; Allen, Pauline; Doheny, Shane; Petsoulas, Christina; Vincent-Jones, Peter

    2013-01-01

    This paper examines NHS secondary care contracting in England and Wales in a period which saw increasing policy divergence between the two systems. At face value, England was making greater use of market levers and utilising harder-edged service contracts incorporating financial penalties and incentives, while Wales was retreating from the 1990 s internal market and emphasising cooperation and flexibility in the contracting process. But there were also cross-border spill-overs involving common contracting technologies and management cultures that meant that differences in on-the-ground contracting practices might be smaller than headline policy differences suggested. The nature of real-world contracting behaviour was investigated by undertaking two qualitative case studies in England and two in Wales, each based on a local purchaser/provider network. The case studies involved ethnographic observations and interviews with staff in primary care trusts (PCTs) or local health boards (LHBs), NHS or Foundation trusts, and the overseeing Strategic Health Authority or NHS Wales regional office, as well as scrutiny of relevant documents. Wider policy differences between the two NHS systems were reflected in differing contracting frameworks, involving regional commissioning in Wales and commissioning by either a PCT, or co-operating pair of PCTs in our English case studies, and also in different oversight arrangements by higher tiers of the service. However, long-term relationships and trust between purchasers and providers had an important role in both systems when the financial viability of organisations was at risk. In England, the study found examples where both PCTs and trusts relaxed contractual requirements to assist partners faced with deficits. In Wales, news of plans to end the purchaser/provider split meant a return to less precisely-specified block contracts and a renewed concern to build cooperation between LHB and trust staff. The interdependency of local

  7. Oak Ridge K-25 Site Technology Logic Diagram. Volume 1, Technology evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Fellows, R.L. [ed.

    1993-02-26

    The Oak Ridge K-25 Technology Logic Diagram (TLD), a decision support tool for the K-25 Site, was developed to provide a planning document that relates environmental restoration and waste management problems at the Oak Ridge K-25 Site to potential technologies that can remediate these problems. The TLD technique identifies the research necessary to develop these technologies to a state that allows for technology transfer and application to waste management, remedial action, and decontamination and decommissioning activities. The TLD consists of four separate volumes-Vol. 1, Vol. 2, Vol. 3A, and Vol. 3B. This Volume, Volume 1 provides introductory and overview information about the TLD. Volume 2 contains logic diagrams. Volume 3 has been divided into two separate volumes to facilitate handling and use. This volume is divided into ten chapters. The first chapter is a brief introduction, and the second chapter details the technical approach of the TLD. These categories are the work activities necessary for successful decontamination and decommissioning, waste management, and remedial action of the K-25 Site. The categories are characterization, decontamination, dismantlement, robotics and automation, remedial action, and waste management. Materials disposition is addressed in Chap. 9. The final chapter contains regulatory compliance information concerning waste management, remedial action, and decontamination and decommissioning.

  8. Management for community-based development and gender equality : - a study of the organisation in co-operatives in El Salvador

    OpenAIRE

    Glod, Anna

    2005-01-01

    This thesis is a result of a field study conducted in El Salvador. Its background lies in previous research pointing on co-operative’s potential to lift whole groups of people out of poverty. Gender equality has been included because of the issues’ importance for economic and social sustainable development and increased growth. The questions posed in this study are how a co-operative should be organised and managed to bring about advantages to its members; and how a co-operative can contribut...

  9. Oak Ridge National Laboratory Technology Logic Diagram. Volume 3, Technology evaluation data sheets: Part B, Dismantlement, Remedial action

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Oak Ridge National Laboratory Technology Logic Diagram (TLD) was developed to provide a decision support tool that relates environmental restoration (ER) and waste management (WM) problems at Oak Ridge National Laboratory (ORNL) to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration testing, and evaluation needed to develop these technologies to a state that allows technology transfer and application to decontamination and decommissioning (D&D), remedial action (RA), and WM activities. The TLD consists of three fundamentally separate volumes: Vol. 1, Technology Evaluation; Vol. 2, Technology Logic Diagram and Vol. 3, Technology EvaLuation Data Sheets. Part A of Vols. 1 and 2 focuses on RA. Part B of Vols. 1 and 2 focuses on the D&D of contaminated facilities. Part C of Vols. 1 and 2 focuses on WM. Each part of Vol. 1 contains an overview of the TM, an explanation of the problems facing the volume-specific program, a review of identified technologies, and rankings of technologies applicable to the site. Volume 2 (Pts. A. B. and C) contains the logic linkages among EM goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 3 (Pts. A. B, and C) contains the TLD data sheets. This volume provides the technology evaluation data sheets (TEDS) for ER/WM activities (D&D, RA and WM) that are referenced by a TEDS code number in Vol. 2 of the TLD. Each of these sheets represents a single logic trace across the TLD. These sheets contain more detail than is given for the technologies in Vol. 2.

  10. Oak Ridge National Laboratory Technology Logic Diagram. Volume 3, Technology evaluation data sheets: Part C, Robotics/automation, Waste management

    Energy Technology Data Exchange (ETDEWEB)

    1993-09-01

    The Oak Ridge National Laboratory Technology Logic Diagram (TLD) was developed to provide a decision support tool that relates environmental restoration (ER) and waste management (WM) problems at Oak Ridge National Laboratory (ORNL) to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration testing, and evaluation needed to develop these technologies to a state that allows technology transfer and application to decontamination and decommissioning (D&D), remedial action (RA), and WM activities. The TLD consists of three fundamentally separate volumes: Vol. 1, Technology Evaluation; Vol. 2, Technology Logic Diagram and Vol. 3, Technology EvaLuation Data Sheets. Part A of Vols. 1 and 2 focuses on RA. Part B of Vols. 1 and 2 focuses on the D&D of contaminated facilities. Part C of Vols. 1 and 2 focuses on WM. Each part of Vol. 1 contains an overview of the TM, an explanation of the problems facing the volume-specific program, a review of identified technologies, and rankings of technologies applicable to the site. Volume 2 (Pts. A. B. and C) contains the logic linkages among EM goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 3 (Pts. A. B, and C) contains the TLD data sheets. This volume provides the technology evaluation data sheets (TEDS) for ER/WM activities (D&D, RA and WM) that are referenced by a TEDS code number in Vol. 2 of the TLD. Each of these sheets represents a single logic trace across the TLD. These sheets contain more detail than is given for the technologies in Vol. 2.

  11. Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method

    Directory of Open Access Journals (Sweden)

    Kellman Peter

    2012-09-01

    Full Text Available Abstract Background Disturbances in the myocardial extracellular volume fraction (ECV, such as diffuse or focal myocardial fibrosis or edema, are hallmarks of heart disease. Diffuse ECV changes are difficult to assess or quantify with cardiovascular magnetic resonance (CMR using conventional late gadolinium enhancement (LGE, or pre- or post-contrast T1-mapping alone. ECV measurement circumvents factors that confound T1-weighted images or T1-maps, and has been shown to correlate well with diffuse myocardial fibrosis. The goal of this study was to develop and evaluate an automated method for producing a pixel-wise map of ECV that would be adequately robust for clinical work flow. Methods ECV maps were automatically generated from T1-maps acquired pre- and post-contrast calibrated by blood hematocrit. The algorithm incorporates correction of respiratory motion that occurs due to insufficient breath-holding and due to misregistration between breath-holds, as well as automated identification of the blood pool. Images were visually scored on a 5-point scale from non-diagnostic (1 to excellent (5. Results The quality score of ECV maps was 4.23 ± 0.83 (m ± SD, scored for n = 600 maps from 338 patients with 83% either excellent or good. Co-registration of the pre-and post-contrast images improved the image quality for ECV maps in 81% of the cases. ECV of normal myocardium was 25.4 ± 2.5% (m ± SD using motion correction and co-registration values and was 31.5 ± 8.7% without motion correction and co-registration. Conclusions Fully automated motion correction and co-registration of breath-holds significantly improve the quality of ECV maps, thus making the generation of ECV-maps feasible for clinical work flow.

  12. Evaluation of Diesel Engine Performance with Intake and Exhaust System Throttling : Volume 2. Appendix 1.

    Science.gov (United States)

    1975-11-01

    The appendix to the preceding volume presents the data for the subject diesel engine noise study, including an engine sound power level analysis and sound spectrums showing the effect of intake and exhaust restrictions.

  13. A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc− Mediates Aglycemic Neuronal Cell Death

    Directory of Open Access Journals (Sweden)

    Trista L. Thorn

    2015-11-01

    Full Text Available The astrocyte cystine/glutamate antiporter (system xc− contributes substantially to the excitotoxic neuronal cell death facilitated by glucose deprivation. The purpose of this study was to determine the mechanism by which this occurred. Using pure astrocyte cultures, as well as, mixed cortical cell cultures containing both neurons and astrocytes, we found that neither an enhancement in system xc− expression nor activity underlies the excitotoxic effects of aglycemia. In addition, using three separate bioassays, we demonstrate no change in the ability of glucose-deprived astrocytes—either cultured alone or with neurons—to remove glutamate from the extracellular space. Instead, we demonstrate that glucose-deprived cultures are 2 to 3 times more sensitive to the killing effects of glutamate or N-methyl-D-aspartate when compared with their glucose-containing controls. Hence, our results are consistent with the weak excitotoxic hypothesis such that a bioenergetic deficiency, which is measureable in our mixed but not astrocyte cultures, allows normally innocuous concentrations of glutamate to become excitotoxic. Adding to the burgeoning literature detailing the contribution of astrocytes to neuronal injury, we conclude that under our experimental paradigm, a cytotoxic, co-operative interaction between energy deprivation and glutamate release from astrocyte system xc− mediates aglycemic neuronal cell death.

  14. SAVING BEHAVIOUR AND DETERMINANTS OF SAVING MOBILIZATION BY RURAL FINANCIAL CO-OPERATORS IN TIGRAI REGION, ETHIOPIA

    Directory of Open Access Journals (Sweden)

    Sebhatu Kifle Tesfamariam

    2012-01-01

    Full Text Available This paper identified and examined saving behaviour and determinants of saving mobiliza-tion by the rural co-operators in Southern Tigrai Ethiopia. The input for the study was ob-tained from randomly selected 120 rural household savers from six purposively selected ru-ral savings and credit cooperatives. The result of the study using least squares method showed that savings mobilized is determined by household annual income, amount of loan borrowed and year of member stay in the cooperative. These factors therefore have to be considered in designing strategies aimed at improving the saving mobilization of coopera-tive members in the study area. Besides, economically feasible cooperative societies in the region should be encouraged among the rural households by supporting them with revolv-ing funds as they are more effective and efficient in mobilizing rural savings and provide collateral plus guarantor-based loans with low default rate. This will enable them to boost up their production output and increase their savings thereby stimulating the rural economy.

  15. Co-operative interactions between first- and second-order mechanisms in the processing of structure from motion.

    Science.gov (United States)

    Aaen-Stockdale, Craig R; Farivar, Reza; Hess, Robert F

    2010-11-11

    Structure from motion (SFM) is the ability to perceive three-dimensional structure from stimuli containing only two-dimensional motion signals and this ability seems to be a result of high-level cortical processes. It has long been thought that local motion signals defined by second-order cues only weakly contribute to perception of SFM since performance on purely second-order SFM tasks is poor, relative to first-order stimuli. We hypothesized that the mechanisms responsible for deriving SFM were insensitive to low-level stimulus attributes such as the first- or second-order nature of the dots composing the stimulus, in other words: that they were "cue-invariant", but that large differences in sensitivity to local first- and second-order motions were responsible for previous findings. By manipulating the relative strength of first-order dots in an SFM stimulus that combines first- and second-order dots, we show that the two types of motion can separately support SFM and co-operatively interact to produce vivid three-dimensional percepts. This provides strong support that the mechanisms underlying SFM are cue-invariant.

  16. GTP information management - the concept of open co-operative planning software; GTP Informationsmanagement - das Konzept offen kooperativer Planungssoftware

    Energy Technology Data Exchange (ETDEWEB)

    Langefeld, O.; Guder, R. [DSK, Herne (Germany); Heim, G. [Technische Hochschule Aachen (Germany). Lehrstuhl und Inst. fuer Bergwerks- und Huettenmaschinenkunde

    2001-03-08

    The aim of the GTP system is to assist the technical planning of panel projects in underground coal mining. Typical requirements on communication and documentation are described with the aid of a schematic representation of the processes. The described concept of open co-operative information management in the environment of GTP planning software is not a final solution. On the contrary it will be shown that an acceptable compromise between the benefits and disadvantages of PC-based data processing can be found by preparation of suitable data structures and information channels. This compromise is also the platform for future developments. (orig.) [German] Das Ziel der GTP-Systeme (Geometrisch technische Planungssysteme) ist die Unterstuetzung der technischen Planung von Bauhoehenprojekten im untertaegigen Steinkohlenbergbau. Anhand einer stark schematisierten Darstellung der Ablaeufe werden typische Anforderungen an die Kommunikation und die Dokumentation beschrieben. Das vorgestellte Konzept eines offen-kooperativen Informationsmanagements im Umfeld der GTP-Planungssoftware stellt keine endgueltige Loesung dar. Vielmehr soll gezeigt werden, dass durch die Bereitstellung geeigneter Datenstrukturen und Informationskanaele ein akzeptabler Kompromiss zwischen Nutzen und Nachteil PC-basierter Datenverarbeitung gefunden werden kann. Dieser Kompromiss ist gleichzeitig die Plattform fuer zukuenftige Entwicklungen. (orig.)

  17. Unemployment and HIV mortality in the countries of the Organisation for Economic Co-operation and Development: 1981-2009.

    Science.gov (United States)

    Maruthappu, Mahiben; Zhou, Charlie; Williams, Callum; Zeltner, Thomas; Atun, Rifat

    2017-07-01

    To determine an association between unemployment rates and human immunodeficiency virus (HIV) mortality in the Organisation for Economic Co-operation and Development (OECD). Multivariate regression analysis. OECD member states. OECD. World Health Organization HIV mortality. Between 1981 and 2009, a 1% increase in unemployment was associated with an increase in HIV mortality in the OECD (coefficient for men 0.711, 0.334-1.089, p  = 0.0003; coefficient for women 0.166, 0.071-0.260, p  = 0.0007). Time lag analysis showed a significant increase in HIV mortality for up to two years after rises in unemployment: p  = 0.0008 for men and p  = 0.0030 for women in year 1, p  = 0.0067 for men and p  = 0.0403 for women in year 2. Rises in unemployment are associated with increased HIV mortality. Economic fiscal policy may impact upon population health. Policy discussions should take into consideration potential health outcomes.

  18. Unemployment and HIV mortality in the countries of the Organisation for Economic Co-operation and Development: 1981–2009

    Science.gov (United States)

    Maruthappu, Mahiben; Williams, Callum; Zeltner, Thomas; Atun, Rifat

    2017-01-01

    Objectives To determine an association between unemployment rates and human immunodeficiency virus (HIV) mortality in the Organisation for Economic Co-operation and Development (OECD). Design Multivariate regression analysis. Participants OECD member states. Setting OECD. Main outcome measures World Health Organization HIV mortality. Results Between 1981 and 2009, a 1% increase in unemployment was associated with an increase in HIV mortality in the OECD (coefficient for men 0.711, 0.334–1.089, p = 0.0003; coefficient for women 0.166, 0.071–0.260, p = 0.0007). Time lag analysis showed a significant increase in HIV mortality for up to two years after rises in unemployment: p = 0.0008 for men and p = 0.0030 for women in year 1, p = 0.0067 for men and p = 0.0403 for women in year 2. Conclusions Rises in unemployment are associated with increased HIV mortality. Economic fiscal policy may impact upon population health. Policy discussions should take into consideration potential health outcomes. PMID:28748096

  19. Sympathetic control of skeletal muscle function: possible co-operation between noradrenaline and neuropeptide Y in rabbit jaw muscles.

    Science.gov (United States)

    Grassi, C; Deriu, F; Roatta, S; Santarelli, R; Azzena, G B; Passatore, M

    1996-07-19

    Stimulation of the cervical sympathetic nerve at 10/s increases by 12.9 +/- 0.7% peak tension of maximal twitches in the directly stimulated jaw muscles and markedly depresses (41.6 +/- 1.3%) the tonic vibration reflex (TVR) elicited in the same muscles by vibration of the mandible. Both effects are not significantly influenced by administration of beta-adrenoceptor antagonists. When both alpha- and beta-adrenergic receptors are blocked, sympathetic stimulation induces a very small increase in twitch tension (3.8 +/- 0.7%), while no detectable change in the TVR is observed. Close arterial injection of alpha 1-adrenoceptor agonist phenylephrine mimics the effects induced by sympathetic stimulation on twitch tension and TVR, dose-dependently. The noradrenaline co-transmitter neuropeptide Y also produces a long-lasting, dose-dependent increase in the twitch tension which is unaffected by blockade of adrenergic receptors as well as of the neuromuscular junctions. Contribution of neuropeptide Y to the sympathetically-induced reduction of the stretch reflex is not clearly demonstrated. These data suggest that co-operation between noradrenaline and neuropeptide Y may be effective in determining sympathetic modulation of skeletal muscle function.

  20. Bedside evaluation of pressure-volume curves in patients with acute respiratory distress syndrome.

    Science.gov (United States)

    Blanch, Lluis; López-Aguilar, Josefina; Villagrá, Ana

    2007-06-01

    To describe the physiologic and diagnostic utility of static pressure-volume curves of the respiratory system at the bedside in patients with acute lung injury or acute respiratory distress syndrome. The pressure-volume curve of the respiratory system is a useful tool for the measurement of respiratory system mechanics in patients with acute lung injury or acute respiratory distress syndrome. The pressure-volume curve has a sigmoid shape, with lower and upper points on the inspiratory limb and a point of maximum curvature on the expiratory limb. Visual and mathematical pressure-volume curve analysis may be useful for understanding individual lung mechanics and for selecting ventilator settings. Among the different techniques for acquiring pressure-volume curves at the bedside, the constant slow flow method is the simplest to perform, the most clinically reliable and has the fewest limitations. Measurement of pressure-volume curves at the bedside in critically ill patients with acute lung injury or acute respiratory distress syndrome should be considered a useful respiratory monitoring tool to assess physiologic lung status and to adjust ventilator settings, when appropriate, to minimize superimposed lung injury associated with mechanical ventilators.

  1. Evaluation of adipose tissue volume quantification with IDEAL fat-water separation.

    Science.gov (United States)

    Alabousi, Abdullah; Al-Attar, Salam; Joy, Tisha R; Hegele, Robert A; McKenzie, Charles A

    2011-08-01

    To validate iterative decomposition of water and fat with echo asymmetry and least-squares estimation (IDEAL) for adipose tissue volume quantification. IDEAL allows MRI images to be produced only from adipose-containing tissues; hence, quantifying adipose tissue should be simpler and more accurate than with current methods. Ten healthy controls were imaged with 1.5 Tesla (T) Spin Echo (SE), 3.0T T1-weighted spoiled gradient echo (SPGR), and 3.0T IDEAL-SPGR. Images were acquired from the abdomen, pelvis, mid-thigh, and mid-calf. Mean subcutaneous and visceral adipose tissue volumes were compared between the three acquisitions for each subject. There were no significant differences (P>0.05) between the three acquisitions for subcutaneous adipose tissue volumes. However, there was a significant difference (P=0.0002) for visceral adipose tissue volumes in the abdomen. Post hoc analysis showed significantly lower visceral adipose tissue volumes measured by IDEAL versus 1.5T (P<0.0001) and 3.0T SPGR (P<0.002). The lower volumes given by IDEAL are due to its ability to differentiate true visceral adipose tissue from other bright structures like blood vessels and bowel content that are mistaken for adipose tissue in non-fat suppressed images. IDEAL measurements of adipose tissue are equivalent to established 1.5T measurement techniques for subcutaneous depots and have improved accuracy for visceral depots, which are more metabolically relevant. Copyright © 2011 Wiley-Liss, Inc.

  2. Browsing Through Closed Books: Evaluation of Preprocessing Methods for Page Extraction of a 3-D CT Book Volume

    Science.gov (United States)

    Stromer, D.; Christlein, V.; Schön, T.; Holub, W.; Maier, A.

    2017-09-01

    It is often the case that a document can not be opened, page-turned or touched anymore due to damages caused by aging processes, moisture or fire. To counter this, special imaging systems can be used. One of our earlier work revealed that a common 3-D X-ray micro-CT scanner is well suited for imaging and reconstructing historical documents written with iron gall ink - an ink consisting of metallic particles. We acquired a volume of a self-made book without opening or page-turning with a single 3-D scan. However, when investigating the reconstructed volume, we faced the problem of a proper automatic extraction of single pages within the volume in an acceptable time without losing information of the writings. Within this work, we evaluate different appropriate pre-processing methods with respect to computation time and accuracy which are decisive for a proper extraction of book pages from the reconstructed X-ray volume and the subsequent ink identification. The different methods were tested for an extreme case with low resolution, noisy input data and wavy pages. Finally, we present results of the page extraction after applying the evaluated methods.

  3. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Miscellaneous -- Volume 3, Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Petrie, L.M.; Jordon, W.C. [Oak Ridge National Lab., TN (United States); Edwards, A.L. [Oak Ridge National Lab., TN (United States)]|[Lawrence Livermore National Lab., CA (United States)] [and others

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice; (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System developments has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. This manual is divided into three volumes: Volume 1--for the control module documentation, Volume 2--for the functional module documentation, and Volume 3--for the data libraries and subroutine libraries.

  4. Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency.

    Science.gov (United States)

    Hansson, Nils Henrik; Tolbod, Lars; Harms, Johannes; Wiggers, Henrik; Kim, Won Yong; Hansen, Esben; Zaremba, Tomas; Frøkiær, Jørgen; Jakobsen, Steen; Sørensen, Jens

    2016-08-01

    Noninvasive estimation of myocardial external efficiency (MEE) requires measurements of left ventricular (LV) oxygen consumption with [(11)C]acetate PET in addition to LV stroke volume and mass with cardiovascular magnetic resonance (CMR). Measuring LV geometry directly from ECG-gated [(11)C]acetate PET might enable MEE evaluation from a single PET scan. Therefore, we sought to establish the accuracy of measuring LV volumes, mass, and MEE directly from ECG-gated [(11)C]acetate PET. Thirty-five subjects with aortic valve stenosis underwent ECG-gated [(11)C]acetate PET and CMR. List mode PET data were rebinned into 16-bin ECG-gated uptake images before measuring LV volumes and mass using commercial software and compared to CMR. Dynamic datasets were used for calculation of mean LV oxygen consumption and MEE. LV mass, volumes, and ejection fraction measured by CMR and PET correlated strongly (r = 0.86-0.92, P PET (P PET-based MEE, corrected for bias, correlated fairly with PET/CMR-based MEE (r = 0.60, P PET-based MEE bias was strongly associated with LV wall thickness. Although analysis-related improvements in accuracy are recommended, LV geometry estimated from ECG-gated [(11)C]acetate PET correlate excellently with CMR and can indeed be used to evaluate MEE.

  5. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Control modules -- Volume 1, Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Landers, N.F.; Petrie, L.M.; Knight, J.R. [Oak Ridge National Lab., TN (United States)] [and others

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. This manual is divided into three volumes: Volume 1--for the control module documentation, Volume 2--for the functional module documentation, and Volume 3 for the documentation of the data libraries and subroutine libraries.

  6. Evaluation of dose-volume histogram parameters (V20 and mean dose) in lung cancer adaptive radiotherapy with design of composite lung volumes (ITV; Evaluacion de parametros del histograma dosis-volumen (V20 y dosis media) en radioterapia adaptada de cancer de pulmon con diseno de volumenes pulmonares compuestos (Internal Target Volume, ITV)

    Energy Technology Data Exchange (ETDEWEB)

    Monroy Anton, J. L.; Solar Tortosa, M.; Lopez Munoz, M.; Navarro Bergada, A.; Estornell gualde, M. A.; Melchor Iniguez, M.

    2013-07-01

    Physiological respiratory motion is a challenge in external radiotherapy for lung tumors. In adaptive radiotherapy, changing position of the target volume should be reflected in the simulation procedure and taken into account in the design of volumes for CTV/PTV proper coverage. This may be achieved through the design of an Internal Target Volume (ITV) as indicated in ICRU-62. However, the Dose-Volume Histogram (DVH) evaluation of the doses received by the healthy lung may vary in the case of designing a single lung volume, compared to the composite lung volume obtained with the fusion of normal breathing, inspiration and expiration (ITV{sub l}ung). (Author)

  7. LONGITUDINAL QUANTITATIVE EVALUATION OF PHOTORECEPTOR VOLUME FOLLOWING REPAIR OF MACULA-OFF RETINAL DETACHMENT.

    Science.gov (United States)

    Narala, Ramsudha; Scarinci, Fabio; Shaarawy, Amr; Simonett, Joseph M; Flaxel, Christina J; Fawzi, Amani A

    2016-08-01

    To quantify photoreceptor volume changes after successful surgical repair of macula-off retinal detachment and to correlate these volumetric changes to postoperative best-corrected visual acuity (BCVA). Retrospective study of 15 eyes of 15 patients with macula-off retinal detachment who underwent successful surgical repair. A minimum of 4 optical coherence tomography scans that straddled the foveal center was used to quantify the central photoreceptor volume (central 1 mm). Mean photoreceptor volume at the first postoperative visit was 0.451 mm, increasing to 0.523 mm at the final postoperative visit (P = 0.004). Mean BCVA improved from 1.13 ± 0.59 logarithm of the minimum angle of resolution units (∼20/270) preoperatively to 0.52 ± 0.42 logarithm of the minimum angle of resolution units (∼20/66) at the final postoperative visit (P = 0.001). Mean photoreceptor volume at either the initial or final visit demonstrated significant correlations with final postoperative BCVA (r = -0.670, P = 0.017 and r = -0.753, P = 0.005, respectively). Shorter time interval from diagnosis to surgery was significantly associated with greater mean final postoperative photoreceptor volume (r = -0.588, P = 0.021) and better mean final postoperative BCVA (r = 0.709, P = 0.003). We observed a significant increase in photoreceptor volume after successful retinal detachment repair; photoreceptor volume was positively associated with BCVA and time to surgery. Our series emphasizes the importance of prompt surgical repair and shows that photoreceptor recovery and volumetric improvement correlate significantly with BCVA.

  8. Evaluating Resident On-Call Performance: Does Volume Affect Discrepancy Rate?

    Science.gov (United States)

    Wildman-Tobriner, Benjamin; Cline, Brendan; Swenson, Christopher; Allen, Brian C; Maxfield, Charles M

    2018-01-06

    To examinehow study volume affects discrepancy rates for on-call radiology residents. Inparticular, we studied how both total shift volume and volume at a particularpoint in time might effect performance. Weretrospectively analyzed 518 weekend call shifts at our institution. The totalnumber of computed tomography (CT) studies per shift was recorded. For everyabdomen-pelvis (AP) or chest-abdomen-pelvis (CAP) CT, preliminary and finalreports were compared for possible discrepancy and rated (by effect on short-termmanagement). We also developed "peristudy volume," defined as CTs read within ±30minutes of a given CT, an estimate of how busy a resident might be at a giventime. We performed logistic regressions to determine whether overall shiftvolume or peristudy volume were predictors of discrepancies. CTvolume/day increased from 58.1 ± 10.1 in 2011 to 75.3 ± 12.5 in 2015(p<0.001). 4695 AP (or CAP) CTs were reviewed, with 145 discrepancies thatcould affect short-term management (3.1%). When reading a study during a shift with≥51 total CTs,residents had increased odds of an error compared to reading a study during ashift with ≤30 studies (OR: 2.97, CI: 1.19-6.46) (p=0.01). When reading a CTwith a peristudy volume of ≥6, residents had increased odds of an error comparedto reading a study with ≤5 peristudy CTs (OR: 1.6, CI: 1.1-2.3) (p=0.01). Whenon-call residents interpret AP CT during high volume shiftsor during busy time-points, odds of discrepancies increase. Awareness of thesedata may inform residency programs in staffing decisions. Copyright © 2018 Elsevier Inc. All rights reserved.

  9. 22 CFR 42.24 - Adoption under the Hague Convention on Protection of Children and Co-operation in Respect of...

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Adoption under the Hague Convention on Protection of Children and Co-operation in Respect of Intercountry Adoption and the Intercountry Adoption Act... Limitations of INA 201 and 202 § 42.24 Adoption under the Hague Convention on Protection of Children and Co...

  10. A European union (EU) co-operation program: Integral, innovative, industrial product design and development, I3PD(2) and project led education (PLE)

    DEFF Research Database (Denmark)

    Nielsen, Sven Hvid

    2007-01-01

    Aalborg University's project-organised and problem-oriented studies were introduced Thirty-three years ago. The experience since then has proved this to be an important innovation in higher education. The primary aim is to teach young people, students to become useful members for industry...... development, teachers mobility, exchange of students and industrial co-operation....

  11. Advanced research workshop "South Caucasus : making the best use of external assistance for stability building and for co-operation with NATO"

    Index Scriptorium Estoniae

    2003-01-01

    Leedu Kaitseministeeriumi poolt 22.-23. septembrini 2003 Vilniuses korraldatud seminaril "South Caucasus: making the best use of external assistance for stability building and for co-operation with NATO" arutati, kas ja kuidas on Lõuna-Kaukaasia regioonis võimalik rakendada Balti riikide julgeolekualase koostöö kogemusi

  12. Protocol to the 2001 co-operation agreement between the European organization for nuclear research (CERN) and the government of the Republic of Croatia

    CERN Document Server

    2001-01-01

    On 19 July 2001, on the basis of the mandate given by Council in 1989 to the Director-General to enter into Co-operation Agreements following a defined text model, CERN and the Government of the Republic of Croatia have entered into a Co-operation Agreement. The new Agreement replaces the Co-operation Agreement of 18 July 1991. As usual, the concrete implementation of the Co-operation Agreement is foreseen to take place through the conclusion of a Protocol. Following an Exchange of Letters on this subject between the Parties, agreement has now been reached on the text of a Protocol concerning the Croatian participation in the LHC Project. In particular, the Protocol stipulates Croatian contributions to the CMS and ALICE Experiments and envisages a possible Croatian contribution to the LHC Computing Grid. Although the Protocol contains no concrete financial commitment by CERN, pending a decision by the Committee of Council on procedures for agreements and protocols, the Management proposes that Finance Committ...

  13. Example of International Co-Operation in the Frame of the Project Phare (TEMPUS) in Innovations in Teaching of Environmental Hydrogeology in Engineering Education in the Czech Republic.

    Science.gov (United States)

    Grmela, Arnost; Rapantova, Nadia

    The international TEMPUS (Trans-European Co-operating and Mobility Scheme for Higher Education between Central/Eastern Europe and European Union) project lasted from 1995-1997. In the framework of TEMPUS, a material and knowledge background was developed in order to ensure the education of the branch Geological Engineering with specialization in…

  14. Organic mixed farms in the landscape of a brook valley. How can a co-operative of organic farms contribute to ecological and aesthetic qualities of a landscape?

    NARCIS (Netherlands)

    Kuiper, J.

    1997-01-01

    Under which conditions would an organic mixed farm co-operative contribute to the aesthetic and ecological quality of the landscape? The orientation of people in space and time is considered an important aspect of aesthetic quality. To facilitate orientation in space and time a landscape should

  15. ‘Joined together there is power, sister’: Re-viewing feminist work from the London Film-makers’ Co-operative

    Directory of Open Access Journals (Sweden)

    Sophie Mayer

    2017-01-01

    Full Text Available The 'From Reel to Real' season of programmes, the first retrospective of women filmmakers' work from the London Film-makers' Co-operative, curated by Maud Jacquin with Tate Modern and LUX, bring together three generations of filmmakers, and highlight the transmission of a political aesthetics that is both theoretically-informed and embodied.

  16. Radiation Field Characterization for the AFRRI TRIGA Reactor. Volume I. Baseline Measurements and Evaluation of Calculational Data.

    Science.gov (United States)

    1981-06-01

    CHARACTERIZATION FOR THE AFRRI TRIGA REACTOR Volume I-Baseline Measurements and Evaluation rŘ of Calculational Data Science Applications, Incorporated...KEY WORDS (Cmehum an re. aide af necoew and Id..ad& by’ Week mbahe) Radiation Neutron-Spectral Mieasurements Samma-Ray Reactor AFRRI TRIGA 26...Characteristics . . . . . . . .. 10 2. Threshold Foil Activations for AFRRI TRIGA ..... .. 18 3. Calculated and Measured Neutron Flux Per Group Per Kilowatt

  17. Integrating model of the Project Independence Evaluation System. Volume IV. Model documentation

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, M L; Allen, B J; Gale, J E; Lutz, M S; O& #x27; Hara, N E; Wood, R K

    1979-02-01

    This volume is the fourth in a series of seven documenting the PIES Integrating Model. It contains detailed descriptions of the basic assumptions behind each of the components of PIES and how they interact with one another. Chapter II of this volume presents the methodology used to integrate supply and demand. It includes a discussion of both the interface between the Demand Model and the equilibrating mechanism and the various supply models via the equilibrating algorithm used by PIES. Chapters III through IX describe each supply submodel in turn: coal, oil, and natural gas supply, utilities, refineries, advanced technologies, and transportation. Code and data documentation are covered elsewhere in this series (Volumes V and VI respectively). PIES is an evolving system. As this document was being prepared, many parts of the model were being modified. This document describes the PIES Integrating Model as of January 1, 1978.

  18. Evaluating and reducing the impact of white matter lesions on brain volume measurements.

    Science.gov (United States)

    Battaglini, Marco; Jenkinson, Mark; De Stefano, Nicola

    2012-09-01

    MR-based measurements of brain volumes may be affected by the presence of white matter (WM) lesions. Here, we assessed how and to what extent this may happen for WM lesions of various sizes and intensities. After inserting WM lesions of different sizes and intensities into T1-W brain images of healthy subjects, we assessed the effect on two widely used automatic methods for brain volume measurement such as SIENAX (segmentation-based) and SIENA (registration-based). To explore the relevance of partial volume (PV) estimation, we performed the experiments with two different PV models, implemented by the same segmentation algorithm (FAST) of SIENAX and SIENA. Finally, we tested potential solutions to this issue. The presence of WM lesions did not bias measurements for registration-based method such as SIENA. By contrast, the presence of WM lesions affected segmentation-based brain volume measurements such as SIENAx. The misclassification of both gray matter (GM) and WM volumes varied considerably with lesion size and intensity, especially when the lesion intensity was similar to that of the GM/WM interface. The extent to which the presence of WM lesions could affect tissue-class measures was clearly driven by the PV modeling used, with the mixel-type PV model giving a lower error in the presence of WM lesions. The tissue misclassification due to WM lesions was still present when they were masked out. By contrast, refilling the lesions with intensities matching the surrounding normal-appearing WM ensured accurate tissue-class measurements and thus represents a promising approach for accurate tissue classification and brain volume measurements. Copyright © 2011 Wiley Periodicals, Inc.

  19. Gas Reactor International Cooperative program. Pebble bed reactor plant: screening evaluation. Volume 3. Appendix A. Equipment list

    Energy Technology Data Exchange (ETDEWEB)

    1979-11-01

    This report consists of three volumes which describe the design concepts and screening evaluation for a 3000 MW(t) Pebble Bed Reactor Multiplex Plant (PBR-MX). The Multiplex plant produces both electricity and transportable chemical energy via the thermochemical pipeline (TCP). The evaluation was limited to a direct cycle plant which has the steam generators and steam reformers in the primary circuit. Volume 1 reports the overall plant and reactor system and was prepared by the General Electric Company. Core scoping studies were performed which evaluated the effects of annular and cylindrical core configurations, radial blanket zones, burnup, and ball heavy metal loadings. The reactor system, including the PCRV, was investigated for both the annular and cylindrical core configurations. Volume 3 is an Appendix containing the equipment list for the plant and was also prepared by United Engineers and Constructors, Inc. It tabulates the major components of the plant and describes each in terms of quantity, type, orientation, etc., to provide a basis for cost estimation.

  20. A synthesis of drug reimbursement decision-making processes in organisation for economic co-operation and development countries.

    Science.gov (United States)

    Barnieh, Lianne; Manns, Braden; Harris, Anthony; Blom, Marja; Donaldson, Cam; Klarenbach, Scott; Husereau, Don; Lorenzetti, Diane; Clement, Fiona

    2014-01-01

    The use of a restrictive formulary, with placement determined through a drug-reimbursement decision-making process, is one approach to managing drug expenditures. To describe the processes in drug reimbursement decision-making systems currently used in national publicly funded outpatient prescription drug insurance plans. By using the Organisation for Economic Co-operation and Development (OECD) nations as the sampling frame, a search was done in the published literature, followed by the gray literature. Collected data were verified by a system expert within the prescription drug insurance plan in each country to ensure the accuracy of key data elements across countries. All but one country provided at least one publicly funded prescription drug formulary. Many systems have adopted similar processes of drug reimbursement decision making. All but three systems required additional consideration of clinical evidence within the decision-making process. Transparency of recommendations varied between systems, from having no information publicly available (three systems) to all information available and accessible to the public (16 systems). Only four countries did not consider cost within the drug reimbursement decision-making process. There were similarities in the decision-making process for drug reimbursement across the systems; however, only five countries met the highest standard of transparency, requirement of evidence, and ability to appeal. Future work should focus on examining how these processes may affect formulary listing decisions for drugs between countries. © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Published by International Society for Pharmacoeconomics and Outcomes Research (ISPOR) All rights reserved.

  1. Pastures, calf production and carcass weights of reindeer calves in the Oraniemi co-operative, Finnish Lapland

    Directory of Open Access Journals (Sweden)

    Jouko Kumpula

    1992-10-01

    Full Text Available The effects of climatic and density-dependent factors on calf production and carcass weights of reindeer calves were studied between the years 1965-87 in the Oraniemi co-operative, Finnish Lapland (67°50´N. The Oraniemi area is divided into five pasture regions, in which the annual home range of the reindeer varied from 300 to 600 km2. The more than trebled reindeer density over the period 1965-87 in Oraniemi had no detrimental effect on calf production (range 15-74 calves/100 females, nor on the mean carcass weight of the calves in 1974-87 (range 16.8-23.2 kg. The annual variations in calf% were explained best by snow conditions during the previous winter and spring and their effects on the nutritional status of the females. The carcass weights of the calves were greater following a warm, rainy May and lower following a warm, rainy June and July. The weather in spring affects the emergence of green vegetation, which is reflected in the condition of females and their milk production, while the weather in early and mid-supper probably affects the quantities of blood-sucking insects and their activity. Carcass weights upon slaughtering rose from September to the beginning of December but then fell quickly. The differences in reindeer densities between the five pasture regions was not reflected in the calf% over the period 1984-87, but the carcass weights of calves were lower following high densities in the pasture regions, especially in the winter pastures.

  2. How to create more supportive supervision for primary healthcare: lessons from Ngamiland district of Botswana: co-operative inquiry group

    Directory of Open Access Journals (Sweden)

    Oathokwa Nkomazana

    2016-06-01

    Full Text Available Background: Supportive supervision is a way to foster performance, productivity, motivation, and retention of health workforce. Nevertheless there is a dearth of evidence of the impact and acceptability of supportive supervision in low- and middle-income countries. This article describes a participatory process of transforming the supervisory practice of district health managers to create a supportive environment for primary healthcare workers. Objective: The objective of the study was to explore how district health managers can change their practice to create a more supportive environment for primary healthcare providers. Design: A facilitated co-operative inquiry group (CIG was formed with Ngamiland health district managers. CIG belongs to the participatory action research paradigm and is characterised by a cyclic process of observation, reflection, planning, and action. The CIG went through three cycles between March 2013 and March 2014. Results: Twelve district health managers participated in the inquiry group. The major insights and learning that emerged from the inquiry process included inadequate supervisory practice, perceptions of healthcare workers’ experiences, change in the managers’ supervision paradigm, recognition of the supervisors’ inadequate supervisory skills, and barriers to supportive supervision. Finally, the group developed a 10-point consensus on what they had learnt regarding supportive supervision. Conclusion: Ngamiland health district managers have come to appreciate the value of supportive supervision and changed their management style to be more supportive of their subordinates. They also developed a consensus on supportive supervision that could be adapted for use nationally. Supportive supervision should be prioritised at all levels of the health system, and it should be adequately resourced.

  3. Evaluating Variations of Bladder Volume Using an Ultrasound Scanner in Rectal Cancer Patients during Chemoradiation: Is Protocol-Based Full Bladder Maintenance Using a Bladder Scanner Useful to Maintain the Bladder Volume?

    Directory of Open Access Journals (Sweden)

    Hong In Yoon

    Full Text Available The maintenance of full bladder is important to reduce radiation-induced toxicities and maintain the therapeutic consistency in locally advanced rectal cancer patients who underwent radiotherapy (RT. So, the aim of this study was to evaluate the effectiveness of protocol-based full bladder maintenance by assessing bladder volume variation using an ultrasound bladder scanner to maintain bladder volume.From March 2011 to May 2011, twenty consecutive rectal cancer patients receiving external beam RT participated in this prospective study. Protocol-based full bladder maintenance consisted of education, training and continuous biofeedback by measuring bladder volume. Bladder volume was measured by bladder scan immediately before simulation CT scan and before each treatment three times weekly during the RT period. The relative bladder volume change was calculated. Intra-patient bladder volume variations were quantified using interquartile range (IQR of relative bladder volume change in each patient. We compared intra-patient bladder volume variations obtained (n=20 with data from our previous study patients (n=20 performing self-controlled maintenance without protocol.Bladder volumes measured by bladder scan highly correlated with those on simulation CT scan (R=0.87, p<0.001. Patients from this study showed lower median IQR of relative bladder volume change compared to patients of self-controlled maintenance from our previous study, although it was not statistically significant (median 32.56% vs. 42.19%, p=0.058. Upon logistic regression, the IQR of relative bladder volume change was significantly related to protocol-based maintenance [relative risk 1.045, 95% confidence intervals (CI 1.004-1.087, p=0.033]. Protocol-based maintenance included significantly more patients with an IQR of relative bladder volume change less than 37% than self-controlled maintenance (p=0.025.Our findings show that bladder volume could be maintained more consistently during

  4. Can prostatic arterial embolisation (PAE) reduce the volume of the peripheral zone? MRI evaluation of zonal anatomy and infarction after PAE

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Yen-Ting [Assistance Publique Hopitaux de Paris. Hopital Europeen Georges-Pompidou, Vascular and Oncological Interventional Radiology, Paris (France); Department of Radiology, Taichung Veterans General Hospital, Taichung City (China); Amouyal, Gregory; Pereira, Helena; Del Giudice, Costantino; Dean, Carole [Assistance Publique Hopitaux de Paris. Hopital Europeen Georges-Pompidou, Vascular and Oncological Interventional Radiology, Paris (France); Correas, Jean-Michel [Assistance Publique Hopitaux de Paris. Hopital Europeen Georges-Pompidou, Vascular and Oncological Interventional Radiology, Paris (France); Hopital Necker, Radiology Department, Paris (France); Pellerin, Olivier; Sapoval, Marc [Assistance Publique Hopitaux de Paris. Hopital Europeen Georges-Pompidou, Vascular and Oncological Interventional Radiology, Paris (France); Inserm (Institut national de la sante et de la recherche medicale) U970, Paris (France); Universite Paris Descartes, Paris (France); Thiounn, Nicolas [Assistance Publique Hopitaux de Paris, Hopital Europeen Georges-Pompidou, Urology, Paris (France)

    2016-10-15

    To assess the impact of prostatic arterial embolisation (PAE) on various prostate gland anatomical zones. We retrospectively reviewed paired MRI scans obtained before and after PAE for 25 patients and evaluated changes in volumes of the median lobe (ML), central gland (CG), peripheral zone (PZ) and whole prostate gland (WPV) following PAE. We used manual segmentation to calculate volume on axial view T2-weighted images for ML, CG and WPV. We calculated PZ volume by subtracting CG volume from WPV. Enhanced phase on dynamic contrasted-enhanced MRI was used to evaluate the infarction areas after PAE. Clinical results of International Prostate Symptom Score and International Index of Erectile Function questionnaires and the urodynamic study were evaluated before and after PAE. Significant reductions in volume were observed after PAE for ML (26.2 % decrease), CG (18.8 %), PZ (16.4 %) and WPV (19.1 %; p < 0.001 for all these volumes). Patients with clinical failure had smaller volume reductions for WPV, ML and CG (all p < 0.05). Patients with significant CG infarction after PAE displayed larger WPV, ML and CG volume reductions (all p < 0.01). PAE can significantly decrease WPV, ML, CG and PZ volumes, and poor clinical outcomes are associated with smaller volume reductions. (orig.)

  5. Evaluation of the free volume theory to predict moisture transport and quality changes during broccoli drying

    NARCIS (Netherlands)

    Jin, X.; Sman, van der R.G.M.; Boxtel, van A.J.B.

    2010-01-01

    Abstract: Moisture diffusion in porous broccoli florets and stalks is modeled by using the free volume and Maxwell-Eucken theories. These theories are based on the mobility of water and show the variation of the effective diffusion coefficient for a wide range of temperatures and moisture content of

  6. Evaluation of the Free Volume Theory to Predict Moisture Transport and Quality Changes During Broccoli Drying

    NARCIS (Netherlands)

    Jin, X.; Sman, van der R.G.M.; Boxtel, van A.J.B.

    2011-01-01

    Moisture diffusion in porous broccoli florets and stalks is modeled using the free volume and Maxwell-Eucken theories. These theories are based on the mobility of water and concern the variation of the effective diffusion coefficient for a wide range of temperature and moisture content during

  7. An Evaluation of the Nutrition Services for the Elderly. Volume I. Executive Summary.

    Science.gov (United States)

    Kirschner Associates, Inc., Albuquerque, NM.

    This document is part of a five-volume nationwide study of Nutrition Services operations and elderly citizens participating in congregate dining and home delivery services authorized by Title III-C of the Older Americans' Act. The Nutrition Services address a number of problems faced by the nation's elderly, such as dietary inadequacy, declining…

  8. An evaluation of known remaining oil resources in the United States: Appendix. Volume 10

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-11-01

    Volume ten contains the following appendices: overview of improved oil recovery methods which covers enhanced oil recovery methods and advanced secondary recovery methods; the benefits of improved oil recovery, selected data for the analyzed states; and list of TORIS fields and reservoirs.

  9. Evaluation of Composting for Reducing Volume of Solid Waste on Contingency Bases

    Science.gov (United States)

    2012-05-23

    electrical current draw – Labor requirements for operations and maintenance • Discharge – Volume removed – Labor requirements for operations and...biodigestion  Low or no water addition reduces equipment size  Near-commercial for equipment size needs  Provides combined heat and power ( CHP

  10. Evaluation of volume and total nucleated cell count as cord blood selection parameters: a receiver operating characteristic curve modeling approach.

    Science.gov (United States)

    Jaime-Pérez, José C; Monreal-Robles, Roberto; Rodríguez-Romo, Laura N; Mancías-Guerra, Consuelo; Herrera-Garza, José Luís; Gómez-Almaguer, David

    2011-11-01

    The objective of the study was to evaluate the current standard practice of using volume and total nucleated cell (TNC) count for the selection of cord blood (CB) units for cryopreservation and further transplantation. Data on 794 CB units whose CD34+ cell content was determined by flow cytometry were analyzed by using a receiver operating characteristic (ROC) curve model to validate the performance of volume and TNC count for the selection of CB units with grafting purposes. The TNC count was the best parameter to identify CB units having 2 × 10(6) or more CD34+ cells, with an area under the ROC curve of 0.828 (95% confidence interval, 0.800-0.856; P < .01) and an efficiency of 75.4%. Combination of parameters (TNC/mononuclear cells [MNCs], efficiency 74.7%; TNC/volume, efficiency 68.9%; and volume/MNCs, efficiency 68.3%) did not lead to improvement in CB selection. All CB units having a TNC count of 8 × 10(8) or more had the required CD34+ cell dose for patients weighing 10 kg or less.

  11. Evaluation of Bacillus oleronius as a Biological Indicator for Terminal Sterilization of Large-Volume Parenterals.

    Science.gov (United States)

    Izumi, Masamitsu; Fujifuru, Masato; Okada, Aki; Takai, Katsuya; Takahashi, Kazuhiro; Udagawa, Takeshi; Miyake, Makoto; Naruyama, Shintaro; Tokuda, Hiroshi; Nishioka, Goro; Yoden, Hikaru; Aoki, Mitsuo

    2016-01-01

    In the production of large-volume parenterals in Japan, equipment and devices such as tanks, pipework, and filters used in production processes are exhaustively cleaned and sterilized, and the cleanliness of water for injection, drug materials, packaging materials, and manufacturing areas is well controlled. In this environment, the bioburden is relatively low, and less heat resistant compared with microorganisms frequently used as biological indicators such as Geobacillus stearothermophilus (ATCC 7953) and Bacillus subtilis 5230 (ATCC 35021). Consequently, the majority of large-volume parenteral solutions in Japan are manufactured under low-heat sterilization conditions of F0 Sterile Pharmaceutical Products Produced by Terminal Sterilization" (guidance in Japan, issued in 2012). In this study, we investigated whether B. oleronius is an appropriate biological indicator of the efficacy of low-heat, moist-heat sterilization of large-volume parenterals. Specifically, we investigated the spore-forming ability of this microorganism in various cultivation media and measured the D-values and z-values as parameters of heat resistance. The D-values and z-values changed depending on the constituents of large-volume parenteral products. Also, the spores from B. oleronius showed a moist-heat resistance that was similar to or greater than many of the spore-forming organisms isolated from Japanese parenteral manufacturing processes. Taken together, these results indicate that B. oleronius is suitable as a biological indicator for sterility assurance of large-volume parenteral solutions subjected to low-heat, moist-heat terminal sterilization. © PDA, Inc. 2016.

  12. Emission trading north - benefits for the economy and the environment. A pilot project of the Energy Foundation Schleswig-Holstein in co-operation with the Association of the Chambers of Industry and Commerce in Schleswig-Holstein and the Union of Employers' Associations in Hamburg and Schleswig-Holstein

    Energy Technology Data Exchange (ETDEWEB)

    Barzantny, Katja [Energiestiftung Schleswig-Holstein, Kiel (Germany); Hahn, Michael [ERM Lahmeyer Int. GmbH, Neu-Isenburg (Germany); Kruska, Martin [EUtech Energie plus Umwelt, Technik plus Management, Aachen (Germany); Klein, Michael [500 PPM Gesellschaft fuer Emissionshandel und Beratung mbH, Hannover (Germany)

    2003-07-01

    In co-operation with the Association of the Chambers of Industry and Commerce in Schleswig-Holstein and the Union of Employers' Associations in Hamburg and Schleswig-Holstein the Energy Foundation Schleswig-Holstein is carrying out the pilot project Emission Trading North. Its primary target is the regional application of the flexible mechanisms (ET, JI, CDM) together with the industry of Schleswig-Holstein. In detail, it focuses on capacity building on behalf of the different parties involved, a smooth transition to real ET and the positioning of the Energy Foundation in a future ET system. The project cycle consists of 3 phases (Phase 0: preparatory work; Phase 1: development of emission inventories, identification and evaluation of emission reduction measures; Phase 2: simulation of ET). Participating companies located in Schleswig-Holstein and Hamburg, representing the power sector, cement production, paper and pulp production, non-ferrous metals as well as the renewable energy sector, dealt with the central question of allocation of emission allowances. During in-depth energy analyses emission reduction measures were identified and evaluated with respect to their volume of emission reductions and related costs. Participating companies developed mid and long-term trading strategies taking into account investment cycles, project risks and market prices. The strategy was tested during a multi-period trading simulation. With respect to the national allocation plan, a central element of the future European emission trading system, the pilot project proposes consistent solutions relating to CHP, capacity limits, process emissions, fuel substitutes, new entrants and shut-down of installations.

  13. Evaluation of economic and technical efficiency of diesel engines operation on the basis of volume combustion rate

    Directory of Open Access Journals (Sweden)

    І. О. Берестовой

    2016-11-01

    Full Text Available The article deals with a new approach to evaluation of complex efficiency of diesel engines. Traditionally, cylinder’s capacity, rotation frequency, average efficient pressure inside cylinder, piston’s stroke, average piston’s velocity, fuel specific consumption and other indices are used as generalizing criteria, characterizing diesel engine’s efficiency, but they do not reflect interrelation between engine’s complex efficiency and a set of economic, mass-dimensional, operational and ecological efficiency. The approach applied in the article makes it possible to reveal the existing and modify the existing methods of solving the problem of improving diesel engine’s efficiency with due regard to interrelation of the parameters, characterizing efficiency of their operation. Statistic analyses were carried out, on the basis of which an assumption regarding the existence of interrelation between specific fuel consumption and the analyzed engine’s parameters was made. Processing of statistical data for various analyzed functions of diesel engines helped offer a function, illustrating the link between volume combustion rate, piston’s area and nominal theoretical specific fuel consumption. Interrelation between volume combustion rate, nominal parameters of diesel operation and efficiency indices, obtained by processing statistical data of more than 500 models of diesels of different series was evaluated, the main feature of it being a mathematical trend. The analysis of the obtained function makes it possible to establish an interrelation between economic efficiency of a diesel, its main index being specific fuel consumption and volume combustion rate and design peculiarities

  14. Evaluation of the reconstruction method and effect of partial volume in brain scintiscanning; Avaliacao do metodo de reconstrucao e efeito do volume parcial em cintilografia cerebral

    Energy Technology Data Exchange (ETDEWEB)

    Pinheiro, Monica Araujo

    2016-10-01

    Alzheimer's disease is a neurodegenerative disorder, on which occurs a progressive and irreversible destruction of neurons. According to the World Health Organization (WHO) 35.6 million people are living with dementia, being recommended that governments prioritize early diagnosis techniques. Laboratory and psychological tests for cognitive assessment are conducted and further complemented by neurological imaging from nuclear medicine exams in order to establish an accurate diagnosis. The image quality evaluation and reconstruction process effects are important tools in clinical routine. In the present work, these quality parameters were studied, and the effects of partial volume (PVE) for lesions of different sizes and geometries that are attributed to the limited resolution of the equipment. In dementia diagnosis, this effect can be confused with intake losses due to cerebral cortex atrophy. The evaluation was conducted by two phantoms of different shapes as suggested by (a) American College of Radiology (ACR) and (b) National Electrical Manufacturers Association (NEMA) for Contrast, Contrast-to-Noise Ratio (CNR) and Recovery Coefficient (RC) calculation versus lesions shape and size. Technetium-99m radionuclide was used in a local brain scintigraphy protocol, for proportions lesion to background of 2:1, 4:1, 6:1, 8:1 and 10:1. Fourteen reconstruction methods were used for each concentration applying different filters and algorithms. Before the analysis of all image properties, the conclusion is that the predominant effect is the partial volume, leading to errors of measurement of more than 80%. Furthermore, it was demonstrate that the most effective method of reconstruction is FBP with Metz filter, providing better contrast and contrast to noise ratio results. In addition, this method shows the best Recovery Coefficients correction for each lesion. The ACR phantom showed the best results assigned to a more precise reconstruction of a cylinder, which does not

  15. Evaluating the effects of white matter multiple sclerosis lesions on the volume estimation of 6 brain tissue segmentation methods.

    Science.gov (United States)

    Valverde, S; Oliver, A; Díez, Y; Cabezas, M; Vilanova, J C; Ramió-Torrentà, L; Rovira, À; Lladó, X

    2015-06-01

    The accuracy of automatic tissue segmentation methods can be affected by the presence of hypointense white matter lesions during the tissue segmentation process. Our aim was to evaluate the impact of MS white matter lesions on the brain tissue measurements of 6 well-known segmentation techniques. These include straightforward techniques such as Artificial Neural Network and fuzzy C-means as well as more advanced techniques such as the Fuzzy And Noise Tolerant Adaptive Segmentation Method, fMRI of the Brain Automated Segmentation Tool, SPM5, and SPM8. Thirty T1-weighted images from patients with MS from 3 different scanners were segmented twice, first including white matter lesions and then masking the lesions before segmentation and relabeling as WM afterward. The differences in total tissue volume and tissue volume outside the lesion regions were computed between the images by using the 2 methodologies. Total gray matter volume was overestimated by all methods when lesion volume increased. The tissue volume outside the lesion regions was also affected by white matter lesions with differences up to 20 cm(3) on images with a high lesion load (≈50 cm(3)). SPM8 and Fuzzy And Noise Tolerant Adaptive Segmentation Method were the methods less influenced by white matter lesions, whereas the effect of white matter lesions was more prominent on fuzzy C-means and the fMRI of the Brain Automated Segmentation Tool. Although lesions were removed after segmentation to avoid their impact on tissue segmentation, the methods still overestimated GM tissue in most cases. This finding is especially relevant because on images with high lesion load, this bias will most likely distort actual tissue atrophy measurements. © 2015 by American Journal of Neuroradiology.

  16. Evaluation of the LWVD Luminosity for Use in the Spectral-Based Volume Sensor Algorithms

    Science.gov (United States)

    2010-04-29

    083 Oct272004_100558 Welding VS4-090 Oct272004_152358 Welding Preceded by No, Normal, and High Rate Ventilation VS4-092 Oct272004_163357 TIG Welding ...applications. 29-04-2010 Memorandum Report Fire detection Optical flame detection Volume sensor Remote sensing Smoke detection Arc welding detection...11 7.3.2. FIRE_FOV and WELDING EVENTs

  17. Economic evaluation of the annual cycle energy system (ACES). Final report. Volume III, appendices

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-01

    This volume consists of seven appendices related to ACES, the first three of which are concerned with computer programs. The appendices are entitled: (A) ACESIM: Residential Program Listing; (B) Typical Inputs and Outputs of ACESIM; (C) CACESS: Commercial Building Program Listing; (D) Typical Weather-Year Selection Requirements; (E) Building Characteristics; (F) List of Major Variables Used in the Computer Programs; and (G) Bibliography. 79 references.

  18. Statistical evaluation of the mechanical properties of high-volume class F fly ash concretes

    KAUST Repository

    Yoon, Seyoon

    2014-03-01

    High-Volume Fly Ash (HVFA) concretes are seen by many as a feasible solution for sustainable, low embodied carbon construction. At the moment, fly ash is classified as a waste by-product, primarily of thermal power stations. In this paper the authors experimentally and statistically investigated the effects of mix-design factors on the mechanical properties of high-volume class F fly ash concretes. A total of 240 and 32 samples were produced and tested in the laboratory to measure compressive strength and Young\\'s modulus respectively. Applicability of the CEB-FIP (Comite Euro-international du Béton - Fédération Internationale de la Précontrainte) and ACI (American Concrete Institute) Building Model Code (Thomas, 2010; ACI Committee 209, 1982) [1,2] to the experimentally-derived mechanical property data for HVFA concretes was established. Furthermore, using multiple linear regression analysis, Mean Squared Residuals (MSRs) were obtained to determine whether a weight- or volume-based mix proportion is better to predict the mechanical properties of HVFA concrete. The significance levels of the design factors, which indicate how significantly the factors affect the HVFA concrete\\'s mechanical properties, were determined using analysis of variance (ANOVA) tests. The results show that a weight-based mix proportion is a slightly better predictor of mechanical properties than volume-based one. The significance level of fly ash substitution rate was higher than that of w/b ratio initially but reduced over time. © 2014 Elsevier Ltd. All rights reserved.

  19. Age estimation by assessment of pulp chamber volume: a Bayesian network for the evaluation of dental evidence.

    Science.gov (United States)

    Sironi, Emanuele; Taroni, Franco; Baldinotti, Claudio; Nardi, Cosimo; Norelli, Gian-Aristide; Gallidabino, Matteo; Pinchi, Vilma

    2017-11-14

    The present study aimed to investigate the performance of a Bayesian method in the evaluation of dental age-related evidence collected by means of a geometrical approximation procedure of the pulp chamber volume. Measurement of this volume was based on three-dimensional cone beam computed tomography images. The Bayesian method was applied by means of a probabilistic graphical model, namely a Bayesian network. Performance of that method was investigated in terms of accuracy and bias of the decisional outcomes. Influence of an informed elicitation of the prior belief of chronological age was also studied by means of a sensitivity analysis. Outcomes in terms of accuracy were adequate with standard requirements for forensic adult age estimation. Findings also indicated that the Bayesian method does not show a particular tendency towards under- or overestimation of the age variable. Outcomes of the sensitivity analysis showed that results on estimation are improved with a ration elicitation of the prior probabilities of age.

  20. The methods of evaluating storage volume for single-chamber reservoir in urban catchments

    Directory of Open Access Journals (Sweden)

    Szeląg Bartosz

    2016-06-01

    Full Text Available The article presents a method of designing single-chamber rectangular detention reservoirs based on nomographs connecting the parameters and the shape of the inflow with the reservoir hydrograph (triangular, described by the power function and described by the gamma distribution as well as the hydraulic characteristics of the accumulation chamber and the orifice. The preparation of nomographs involved using the SWMM (Storm Water Management Model program with the application of numerical calculations’ results of a differential equation for the stormwater volume balance. The performed analyses confirm a high level of similarity between the results of calculating the reservoir volume obtained by using the above mentioned program and using the developed nomographs. The examples of calculations presented in the paper confirm the application aspects of the discussed method of designing the detention reservoir. Moreover, based on the conducted analyses it was concluded that the inflow hydrograph described by the gamma distribution has the greatest impact on the reservoir’s storage volume, whereas the hydrograph whose shape in the rise and recession phases is described by the power function has the smallest effect.

  1. [Ultrasound evaluation of fetal adrenal gland volume. The role of fetal adrenal glands in the pathogenesis of preterm labor].

    Science.gov (United States)

    Krzyzanowski, Arkadiusz; Karwasik-Kajszczarek, Katarzyna; Dymanowska-Dyjak, Izabela; Kondracka, Adrianna; Kwaśniewska, Anna

    2014-02-01

    Preterm labor remains to be one of the most important challenges of contemporary perinatology and constitutes the main reason of perinatal mortality and prematurity of neonates. Studies on preterm labor have confirmed the mutual interactions of several different hormonal systems while the activation of hypothalamic- pituitary- adrenal axis seems to have the greatest influence. It has been also suggested that size and mass of fetal adrenal glands may be associated with the risk of preterm labor. Several authors have shown that the evaluation of fetal adrenal gland volume may be a useful marker of fetal growth during pregnancy. Technological advancements enabled the development of three-dimensional ultrasound evaluation (3D) of the fetal adrenal glands, facilitating a more precise evaluation of their volume. Also, it seems to have higher sensitivity and specificity than two-dimensional ultrasonography (2D). Studies have confirmed a direct relationship between fetal adrenal gland size and the onset of preterm labor within at least 1 week since the ultrasound exam. They have also suggested that in a physiological pregnancy the relation between fetal zone and the whole organ remains constant throughout the pregnancy. Disruption of these proportions and fetal zone enlargement are considered to be a marker of labor cascade and preterm labor with significantly higher sensitivity and specificity than ultrasound evaluation of the cervical length and assessment of the fetal fibronectin concentration.

  2. MoDOT pavement preservation research program volume IV, pavement evaluation tools-data collection methods.

    Science.gov (United States)

    2015-10-01

    The overarching goal of the MoDOT Pavement Preservation Research Program, Task 3: Pavement Evaluation Tools Data : Collection Methods was to identify and evaluate methods to rapidly obtain network-level and project-level information relevant to :...

  3. Revamping the Teacher Evaluation Process. Education Policy Brief. Volume 9, Number 4, Fall 2011

    Science.gov (United States)

    Whiteman, Rodney S.; Shi, Dingjing; Plucker, Jonathan A.

    2011-01-01

    This policy brief explores Senate Enrolled Act 001 (SEA 1), specifically the provisions for how teachers must be evaluated. After a short summary of SEA 1 and its direct changes to evaluation policies and practices, the brief reviews literature in teacher evaluation and highlights important issues for school corporations to consider when selecting…

  4. Thou should not know too much. When lack of information promotes co-operative behaviour. The case of oil-fields in Wyoming, Oklahoma and Texas

    Energy Technology Data Exchange (ETDEWEB)

    Hassler, B.

    1997-12-31

    Proper assumptions of information levels are of vital importance in all kinds of analysis of interdependent decision-making. In most cases the rule is; the more information the better. In this paper, however, it is shown that such is not always the case. Lack of information can enhance resource utilisation of resources, when the problem of co-operation is of a Prisoner`s dilemma type, and when iteration of the interaction game is unlikely. The case of oil-fields in the United States has been chosen as an empirical example of the latter. Optimal drilling procedures tend to be chosen more often the less the drillers know about the resource characteristics. This outcome is explained by the structure of the decision-making problem, where low levels of information render it advantageous to choose co-operative strategies 16 refs, 4 figs

  5. Theoretical Foundations of the Web: Cognition, Communication, and Co-Operation. Towards an Understanding of Web 1.0, 2.0, 3.0

    Directory of Open Access Journals (Sweden)

    Robert Bichler

    2010-02-01

    Full Text Available Currently, there is much talk of Web 2.0 and Social Software. A common understanding of these notions is not yet in existence. The question of what makes Social Software social has thus far also remained unacknowledged. In this paper we provide a theoretical understanding of these notions by outlining a model of the Web as a techno-social system that enhances human cognition towards communication and co-operation. According to this understanding, we identify three qualities of the Web, namely Web 1.0 as a Web of cognition, Web 2.0 as a Web of human communication, and Web 3.0 as a Web of co-operation. We use the terms Web 1.0, Web 2.0, Web 3.0 not in a technical sense, but for describing and characterizing the social dynamics and information processes that are part of the Internet.

  6. Integrating model of the Project Independence Evaluation System. Volume VI. Data documentation. Part I

    Energy Technology Data Exchange (ETDEWEB)

    Allen, B J

    1979-02-01

    This documentation describes the PIES Integrating Model as it existed on January 1, 1978. This volume contains two chapters. In Chapter I, Overview, the following subjects are briefly described: supply data, EIA projection series and scenarios, demand data and assumptions, and supply assumptions - oil and gas availabilities. Chapter II contains supply and demand data tables and sources used by the PIES Integrating Model for the mid-range scenario target years 1985 and 1990. Tabulated information is presented for demand, price, and elasticity data; coal data; imports data; oil and gas data; refineries data; synthetics, shale, and solar/geothermal data; transportation data; and utilities data.

  7. H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development (third from left) with (left to right) Florian Ciolacu (Romanian Mission in Geneva), Cornel Comsa (personal adviser to the Prince), Sorin Ilie (CERN), Calin Alexa (ATLAS), Iosif Legrand (Caltech/CMS), Mihaela Gheata (ALICE), Andrei Gheata (ALICE), and Sorin Zgura (ALICE).

  8. Autonomous Co-operation and Control in Complex Adaptive Logistic Systems - Contributions and Limitations for the Innovation Capability of International Supply Networks

    Science.gov (United States)

    Hülsmann, Michael; Cordes, Philip

    This paper aims to analyze the potential contributions of the organization principle autonomous co-operation and control to the innovation capabilities of logistics systems and their sub-systems like single organizations. Therefore, the concept of Complex Adaptive Logistics Systems (CALS) will be introduced and the essentiality of the heterogeneity of the elements within logistics systems for their innovation capabilities will be emphasized. One possible driver for homogeneity is the so-called dominant logic.

  9. Evaluation of lung volumes, vital capacity and respiratory muscle strength after cervical, thoracic and lumbar spinal surgery.

    Science.gov (United States)

    Oliveira, Marcio Aparecido; Vidotto, Milena Carlos; Nascimento, Oliver Augusto; Almeida, Renato; Santoro, Ilka Lopes; Sperandio, Evandro Fornias; Jardim, José Roberto; Gazzotti, Mariana Rodrigues

    2015-01-01

    Studies have shown that physiopathological changes to the respiratory system can occur following thoracic and abdominal surgery. Laminectomy is considered to be a peripheral surgical procedure, but it is possible that thoracic spinal surgery exerts a greater influence on lung function. The aim of this study was to evaluate the pulmonary volumes and maximum respiratory pressures of patients undergoing cervical, thoracic or lumbar spinal surgery. Prospective study in a tertiary-level university hospital. Sixty-three patients undergoing laminectomy due to diagnoses of tumors or herniated discs were evaluated. Vital capacity, tidal volume, minute ventilation and maximum respiratory pressures were evaluated preoperatively and on the first and second postoperative days. Possible associations between the respiratory variables and the duration of the operation, surgical diagnosis and smoking status were investigated. Vital capacity and maximum inspiratory pressure presented reductions on the first postoperative day (20.9% and 91.6%, respectively) for thoracic surgery (P = 0.01), and maximum expiratory pressure showed reductions on the first postoperative day in cervical surgery patients (15.3%; P = 0.004). The incidence of pulmonary complications was 3.6%. There were reductions in vital capacity and maximum respiratory pressures during the postoperative period in patients undergoing laminectomy. Surgery in the thoracic region was associated with greater reductions in vital capacity and maximum inspiratory pressure, compared with cervical and lumbar surgery. Thus, surgical manipulation of the thoracic region appears to have more influence on pulmonary function and respiratory muscle action.

  10. Hazard ranking system evaluation of CERCLA inactive waste sites at Hanford: Volume 2: Engineered-facility sites (HISS data base)

    Energy Technology Data Exchange (ETDEWEB)

    Jette, S.J.; Lamar, D.A.; McLaughlin, T.J.; Sherwood, D.R.; Van Houten, N.C.; Stenner, R.D.; Cramer, K.H.; Higley, K.A.

    1988-10-01

    The purpose of this report is to formally document the assessment activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that address the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) Program for the cleanup of inactive waste sites. The DOE orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986. This methodology includes: PA/SI, remedial investigation/feasibility study, record of decision, design and implementation of remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the Hazard Ranking System methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 13 refs.

  11. Falling between two stools; how a weak co-operation between the social security and the unemployment agencies obstructs rehabilitation of unemployed sick-listed persons.

    Science.gov (United States)

    Eriksson, Ulla Britt; Engström, Lars-Gunnar; Starrin, Bengt; Janson, Staffan

    2008-01-01

    To explore significant factors behind the weak co-operation between local social insurance and unemployment agencies impairing the rehabilitation of unemployed sick-listed persons. Individual, semi-structured face-to-face interviews with main actors directly involved in the sick-listing and rehabilitation process were conducted in the year 2000. In all 39 persons were interviewed: 25 professionals (physicians, public employment and social insurance officers) and 14 clients. Data were analysed according to Grounded theory method. The majority of unemployed sick-listed persons were declared too sick to work and were erased from the unemployment registers. This measure weakened the incentives for co-operation between the two main rehabilitation actors. The implication was that the unemployed sick-listed persons lost the opportunity of the co-ordinated rehabilitation they were entitled to. Three significant factors behind this process were identified by the main actors: indistinct regulation of co-operation, shifting political goals over time and conflicting goals between agencies; the last factor mainly a consequence of the other two. The findings suggest that labour market changes and manifest political goals influence the rehabilitation efforts giving low priority to difficult-to-place individuals such as unemployed sick-listed persons. In fact, a labour market problem turns into a medical problem. The hypothesis needs further testing in quantitative studies.

  12. The importance of total kidney volume in evaluating progression of polycystic kidney disease

    Science.gov (United States)

    Grantham, Jared J.; Torres, Vicente E.

    2017-01-01

    The rate at which autosomal dominant polycystic kidney disease (ADPKD) progresses to end-stage renal disease varies widely and is determined by genetic and non-genetic factors. The ability to determine the prognosis of children and young adults with ADPKD is important for the effective life-long management of the disease and to enable the efficacy of emerging therapies to be determined. Total kidney volume (TKV) reflects the sum volume of hundreds of individual cysts with potentially devastating effects on renal function. The sequential measurement of TKV has been advanced as a dynamic biomarker of disease progression, yet doubt remains among nephrologists and regulatory agencies as to its usefulness. Here, we review the mechanisms that lead to an increase in TKV in ADPKD, and examine the evidence supporting the conclusion that TKV provides a metric of disease progression that can be used to assess the efficacy of potential therapeutic regimens in children and adults with ADPKD. Moreover, we propose that TKV can be used to monitor treatment efficacy in patients with normal levels of renal function, before the pathologic processes of ADPKD cause extensive fibrosis and irreversible loss of functioning renal tissue. PMID:27694979

  13. Photovoltaic system criteria documents. Volume 3: Environmental issues and evaluation criteria for photovoltaic applications

    Science.gov (United States)

    Koenig, John C.; Billitti, Joseph W.; Tallon, John M.

    1979-01-01

    The environmental issues and evaluation criteria relating to the suitability of sites proposed for photovoltaic (PV) system deployment are identified. The important issues are defined, briefly discussed and then developed into evaluation criteria. System designers are provided with information on the environmental sensitivity of PV systems in realistic applications, background material which indicates the applicability of the siting issues identified, and evaluation criteria are defined to facilitate the selection of sites that maximize PV system operation.

  14. Evaluation of spacecraft technology programs (effects on communication satellite business ventures), volume 2

    Science.gov (United States)

    Greenburg, J. S.; Kaplan, M.; Fishman, J.; Hopkins, C.

    1985-01-01

    The computational procedures used in the evaluation of spacecraft technology programs that impact upon commercial communication satellite operations are discussed. Computer programs and data bases are described.

  15. Reservoir volume optimization and performance evaluation of rooftop catchment systems in arid regions: A case study of Birjand, Iran

    Directory of Open Access Journals (Sweden)

    Zinat Komeh

    2017-04-01

    Full Text Available This study evaluated the performance of rooftop catchment systems in securing non-potable water supply in Birjand, located in an arid area in southeastern Iran. The rooftop catchment systems at seven study sites of different residential buildings were simulated for dry, normal, and wet water years, using 31-year rainfall records. The trial and error approach and mass diagram method were employed to optimize the volume of reservoirs in five different operation scenarios. Results showed that, during the dry water year from 2000 to 2001, for reservoirs with volumes of 200–20000 L, the proportion of days that could be secured for non-portable water supply was on average computed to be 16.4%–32.6% across all study sites. During the normal water year from 2009 to 2010 and the wet water year from 1995 to 1996, for reservoirs with volumes of 200–20000 L, the proportions were 20.8%–69.6% and 26.8%–80.3%, respectively. Therefore, a rooftop catchment system showed a high potential to meet a significant portion of non-potable water demand in the Birjand climatic region. Reservoir volume optimization using the mass diagram method produced results consistent with those obtained with the trial and error approach, except at sites #1, #2, and #5. At these sites, the trial and error approach performed better than the mass diagram method due to relatively high water consumption. It is concluded that the rooftop catchment system is applicable under the same climatic conditions as the study area, and it can be used as a drought mitigation strategy as well.

  16. “Not Just an Apartment Building”: Residents’ Quality of Life in a Social Housing Co-operative

    Directory of Open Access Journals (Sweden)

    Angela Eileen Wisniewski

    2010-01-01

    Full Text Available The objective of this study was to examine the impact that two social housing complexes have had on their residents' quality of life. These two complexes, known as Tannery Court Co-operative Ltd., target a specific segment of the affordable housing market: non-elderly singles. A mixed-methods approach was used to assess the quality of life of residents. The data collection strategy used semi-structured interviews conducted with the help of a questionnaire. A total of 43 interviews were completed at the two building sites. Analysis of interview and questionnaire data identified six areas of improvement in residents' quality of life. These are life in general (an overarching dimension, housing (the focus of the Tannery Court intervention, neighbourhood (including safety and appearance, food, self-confidence (an enabling dimension for future development of projects and goals among the residents, and financial situation (a key dimension because of its multiple impacts on other aspects of life. / L'objectif de cette recherche était d'évaluer l'impact des deux complexes de logements coopératifs Tannery Court sur la qualité de vie des résidants. Ces complexes ciblent un segment particulier du marché du logement social, les célibataires d'âge actif et vivant en deçà du seuil de la pauvreté. Cette étude utilise une méthodologie mixte pour évaluer la situation et la qualité de vie des résidants. La stratégie de cueillette de données s'appuie sur des entrevues semi-dirigées effectuées à l'aide d'un questionnaire. Au total, nous avons complété 43 entrevues. Six aspects de la qualité de vie se sont améliorés de façon significative. Il s'agit de la vie en général (une dimension globale, le logement (l'objectif premier visé par l'équipe de Tannery Court, le quartier de résidence (dimensions importantes de la localisation d'un complexe comme la sécurité et l'apparence la confiance en soi (une dimension clé pour le d

  17. Excised leaf method for high volume evaluation of sorghum germplasm for resistance against Colletotrichum sublineolum

    Science.gov (United States)

    Foliar phase of anthracnose, caused by Colletotrichum sublineolum is the most important leaf disease of sorghum. Due to the hyper-variable nature of the fungus, continuous evaluation of sorghum germplasm to identify new sources of resistance is imperative. Field and greenhouse evaluations for anth...

  18. Super-Efficient Refrigerator Program (SERP) evaluation volume 2: Preliminary impact and market transformation assessment

    Energy Technology Data Exchange (ETDEWEB)

    Lee, A.D.; Conger, R.L.

    1996-08-01

    The Super Efficient Refrigerator Program (SERP) is a collaborative utility program intended to transform the market for energy-efficient and environmentally friendly refrigerators. It is one of the first examples of a large-scale {open_quotes}market transformation{close_quotes} energy efficiency program. This report documents the preliminary impact and market transformation evaluation of SERP ({open_quotes}the Program{close_quotes}). Pacific Northwest National Laboratory (PNNL) conducted this evaluation for the U.S. Department of Energy. This study focuses on the preliminary impact evaluation and market transformation assessment, but also presents limited process evaluation information. It is based on interviews with refrigerator dealers and manufacturers, interviews with utility participants, industry data, and information from the Program administrators. Results from this study complement those from prior process evaluation also conducted by PNNL. 42 refs., 5 figs., 4 tabs.

  19. Noninvasive Evaluation of Bladder Wall Mechanical Properties as a Function of Filling Volume: Potential Application in Bladder Compliance Assessment.

    Directory of Open Access Journals (Sweden)

    Ivan Nenadic

    Full Text Available We propose a novel method to monitor bladder wall mechanical properties as a function of filling volume, with the potential application to bladder compliance assessment. The proposed ultrasound bladder vibrometry (UBV method uses ultrasound to excite and track Lamb waves on the bladder wall from which its mechanical properties are derived by fitting measurements to an analytical model. Of particular interest is the shear modulus of bladder wall at different volumes, which we hypothesize, is similar to measuring the compliance characteristics of the bladder.Three experimental models were used: 1 an ex vivo porcine model where normal and aberrant (stiffened by formalin bladders underwent evaluation by UBV; 2 an in vivo study to evaluate the performance of UBV on patients with clinically documented compliant and noncompliant bladders undergoing UDS; and 3 a noninvasive UBV protocol to assess bladder compliance using oral hydration and fractionated voiding on three healthy volunteers.The ex vivo studies showed a high correlation between the UBV parameters and direct pressure measurement (R2 = 0.84-0.99. A similar correlation was observed for 2 patients with compliant and noncompliant bladders (R2 = 0.89-0.99 undergoing UDS detrusor pressure-volume measurements. The results of UBV on healthy volunteers, performed without catheterization, were comparable to a compliant bladder patient.The utility of UBV as a method to monitor changes in bladder wall mechanical properties is validated by the high correlation with pressure measurements in ex vivo and in vivo patient studies. High correlation UBV and UDS in vivo studies demonstrated the potential of UBV as a bladder compliance assessment tool. Results of studies on healthy volunteers with normal bladders demonstrated that UBV could be performed noninvasively. Further studies on a larger cohort are needed to fully validate the use of UBV as a clinical tool for bladder compliance assessment.

  20. Accuracy evaluation of Fourier series analysis and singular spectrum analysis for predicting the volume of motorcycle sales in Indonesia

    Science.gov (United States)

    Sasmita, Yoga; Darmawan, Gumgum

    2017-08-01

    This research aims to evaluate the performance of forecasting by Fourier Series Analysis (FSA) and Singular Spectrum Analysis (SSA) which are more explorative and not requiring parametric assumption. Those methods are applied to predicting the volume of motorcycle sales in Indonesia from January 2005 to December 2016 (monthly). Both models are suitable for seasonal and trend component data. Technically, FSA defines time domain as the result of trend and seasonal component in different frequencies which is difficult to identify in the time domain analysis. With the hidden period is 2,918 ≈ 3 and significant model order is 3, FSA model is used to predict testing data. Meanwhile, SSA has two main processes, decomposition and reconstruction. SSA decomposes the time series data into different components. The reconstruction process starts with grouping the decomposition result based on similarity period of each component in trajectory matrix. With the optimum of window length (L = 53) and grouping effect (r = 4), SSA predicting testing data. Forecasting accuracy evaluation is done based on Mean Absolute Percentage Error (MAPE), Mean Absolute Error (MAE) and Root Mean Square Error (RMSE). The result shows that in the next 12 month, SSA has MAPE = 13.54 percent, MAE = 61,168.43 and RMSE = 75,244.92 and FSA has MAPE = 28.19 percent, MAE = 119,718.43 and RMSE = 142,511.17. Therefore, to predict volume of motorcycle sales in the next period should use SSA method which has better performance based on its accuracy.

  1. A Study on the Evaluation of Field Application of High-Fluidity Concrete Containing High Volume Fly Ash

    Directory of Open Access Journals (Sweden)

    Yun-Wang Choi

    2015-01-01

    Full Text Available In the recent concrete industry, high-fluidity concrete is being widely used for the pouring of dense reinforced concrete. Normally, in the case of high-fluidity concrete, it includes high binder contents, so it is necessary to replace part of the cement through admixtures such as fly ash to procure economic feasibility and durability. This study shows the mechanical properties and field applicability of high-fluidity concrete using mass of fly ash as alternative materials of cement. The high-fluidity concrete mixed with 50% fly ash was measured to manufacture concrete that applies low water/binder ratio to measure the mechanical characteristics as compressive strength and elastic modulus. Also, in order to evaluate the field applicability, high-fluidity concrete containing high volume fly ash was evaluated for fluidity, compressive strength, heat of hydration, and drying shrinkage of concrete.

  2. Evaluated kinetic and photochemical data for atmospheric chemistry: Volume V – heterogeneous reactions on solid substrates

    Directory of Open Access Journals (Sweden)

    J. N. Crowley

    2010-09-01

    Full Text Available This article, the fifth in the ACP journal series, presents data evaluated by the IUPAC Subcommittee on Gas Kinetic Data Evaluation for Atmospheric Chemistry. It covers the heterogeneous processes on surfaces of solid particles present in the atmosphere, for which uptake coefficients and adsorption parameters have been presented on the IUPAC website in 2010. The article consists of an introduction and guide to the evaluation, giving a unifying framework for parameterisation of atmospheric heterogeneous processes. We provide summary sheets containing the recommended uptake parameters for the evaluated processes. Four substantial appendices contain detailed data sheets for each process considered for ice, mineral dust, sulfuric acid hydrate and nitric acid hydrate surfaces, which provide information upon which the recommendations are made.

  3. Evaluated kinetic and photochemical data for atmospheric chemistry: Volume VI – heterogeneous reactions with liquid substrates

    Directory of Open Access Journals (Sweden)

    M. Ammann

    2013-08-01

    Full Text Available This article, the sixth in the ACP journal series, presents data evaluated by the IUPAC Task Group on Atmospheric Chemical Kinetic Data Evaluation. It covers the heterogeneous processes involving liquid particles present in the atmosphere with an emphasis on those relevant for the upper troposphere/lower stratosphere and the marine boundary layer, for which uptake coefficients and adsorption parameters have been presented on the IUPAC website since 2009. The article consists of an introduction and guide to the evaluation, giving a unifying framework for parameterisation of atmospheric heterogeneous processes. We provide summary sheets containing the recommended uptake parameters for the evaluated processes. The experimental data on which the recommendations are based are provided in data sheets in separate appendices for the four surfaces considered: liquid water, deliquesced halide salts, other aqueous electrolytes and sulfuric acid.

  4. Evaluation of the intelligent cruise control system : volume 1 : study results

    Science.gov (United States)

    1999-10-01

    The Intelligent Cruise Control (ICC) system evaluation was based on an ICC Field Operational Test (FOT) performed in Michigan. The FOT involved 108 volunteers recruited to drive ten ICC-equipped Chrysler Concordes. Testing was initiated in July 1996 ...

  5. Ocean thermal energy conversion (OTEC) platform configuration and integration. Final report. Volume I. Systems requirements and evaluation

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-06-01

    Studies leading to the development of two 400 MW Offshore Thermal Energy Conversion Commercial Plants are presented. This volume includes a summary of three tasks: task IIA--systems evaluation and requirements; task IIB--evaluation plan; task III--technology review; and task IV--systems integration evaluation. Task IIA includes the definition of top level requirements and an assessment of factors critical to the selection of hull configuration and size, quantification of payload requirements and characteristics, and sensitivity of system characteristics to site selection. Task IIB includes development of a methodology for systematically evaluating the candidate hullforms, based on interrelationships and priorities developed during task IIA. Task III includes the assessment of current technology and identification of deficiencies in relation to OTEC requirements and the development of plans to correct such deficiencies. Task IV involves the formal evaluation of the six candidate hullforms in relation to sit and plant capacity to quantify cost/size/capability relationships, leading to selection of an optimum commercial plant. (WHK)

  6. A comprehensive quantitative and qualitative evaluation of extrapolation of intravenous pharmacokinetic parameters from rat, dog, and monkey to humans. II. Volume of distribution and mean residence time.

    Science.gov (United States)

    Ward, Keith W; Smith, Brian R

    2004-06-01

    Our laboratory is engaged in an ongoing analysis of a 103-compound data set containing reliable intravenous pharmacokinetic parameters in the rat, dog, monkey, and human, and we have previously reported our findings regarding extrapolation of clearance. In this article, we report on our findings regarding volume of distribution and mean residence time. Various allometric and nonallometric methods were used to predict human volume of distribution based on preclinical pharmacokinetic data; clearance and volume of distribution values generated by various means were then used to estimate mean residence time. From both a quantitative and qualitative perspective, estimating human volume and mean residence time based on monkey data alone was the most accurate approach evaluated. For volume, estimation based on monkey data alone was quantitatively the least biased of all approaches evaluated. Additionally, prediction of mean residence time based on clearance and volume from the monkey was the only extrapolation method that exhibited a positive, rather than negative, bias. None of the allometric scaling approaches investigated afforded optimal predictivity for either volume or mean residence time, and neither the correlation coefficient nor the allometric exponent allowed a prospective estimation of predictive success or failure. These observations regarding volume and mean residence time confirm our earlier results with clearance, and further confirm the value of the monkey as a species for pharmacokinetic lead optimization.

  7. The Evaluation of a Noninvasive Respiratory Volume Monitor in Pediatric Patients Undergoing General Anesthesia.

    Science.gov (United States)

    Gomez-Morad, Andrea D; Cravero, Joseph P; Harvey, Brian C; Bernier, Rachel; Halpin, Erin; Walsh, Brian; Nasr, Viviane G

    2017-12-01

    Pediatric patients following surgery are at risk for respiratory compromise such as hypoventilation and hypoxemia depending on their age, comorbidities, and type of surgery. Quantitative measurement of ventilation in nonintubated infants/children is a difficult and inexact undertaking. Current respiratory assessment in nonintubated patients relies on oximetry data, respiratory rate (RR) monitors, and subjective clinical assessment, but there is no objective measure of respiratory parameters that could be utilized to predict early respiratory compromise. New advances in technology and digital signal processing have led to the development of an impedance-based respiratory volume monitor (RVM, ExSpiron, Respiratory Motion, Inc, Waltham, MA). The RVM has been shown to provide accurate real-time, continuous, noninvasive measurements of tidal volume (TV), minute ventilation (MV), and RR in adult patients.In this prospective observational study, our primary aim was to determine whether the RVM accurately measures TV, RR, and MV in pediatric patients. A total of 72 pediatric patients (27 females, 45 males), ASA I to III, undergoing general anesthesia with endotracheal intubation were enrolled. After endotracheal intubation, continuous data of MV, TV, and RR were recorded from the RVM and an in-line monitoring spirometer (NM3 monitor, Phillips Healthcare). RVM and NM3 measurements of MV, TV, and RR were compared during a 10-minute period prior to the incision ("Presurgery") and a 10-minute period after the end of surgery ("Postsurgery"). Relative errors were calculated over 1-minute segment within each 10-minute period. Bias, precision, and accuracy were calculated using Bland-Altman analyses and paired-difference equivalence tests were performed. Combined across the Presurgery and Postsurgery periods, the RVM's mean measurement bias (RVM - NM3 measurement) for MV was -3.8% (95% limits of agreement) (±1.96 SD): (-19.9% to 12.2%), for TV it was -4.9 (-21.0% to 11.3%), and

  8. Human factors evaluation of teletherapy: Human-system interfaces and procedures. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Kaye, R.D.; Henriksen, K.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations was undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multidisciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. The principal sources of radiation are a radioactive isotope, typically cobalt60 (Co-60), or a linear accelerator device capable of producing very high energy x-ray and electron beams. A team of human factors specialists conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. In addition, a panel of radiation oncologists, medical physicists, and radiation technologists served as subject matter experts. A function and task analysis was initially performed to guide subsequent evaluations in the areas of user-system interfaces, procedures, training and qualifications, and organizational policies and practices. The present report focuses on an evaluation of the human-system interfaces in relation to the treatment machines and supporting equipment (e.g., simulators, treatment planning computers, control consoles, patient charts) found in the teletherapy environment. The report also evaluates operating, maintenance and emergency procedures and practices involved in teletherapy. The evaluations are based on the function and task analysis and established human engineering guidelines, where applicable.

  9. Human factors evaluation of teletherapy: Training and organizational analysis. Volume 4

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, K.; Kaye, R.D.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations were undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multidisciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation therapists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was initially performed to guide subsequent evaluations in the areas of system-user interfaces, procedures, training and qualifications, and organizational policies and practices. The present work focuses solely on training and qualifications of personnel (e.g., training received before and during employment), and the potential impact of organizational factors on the performance of teletherapy. Organizational factors include such topics as adequacy of staffing, performance evaluations, commonly occurring errors, implementation of quality assurance programs, and organizational climate.

  10. Global Spent Fuel Logistics Systems Study (GSFLS). Volume 2. GSFLS visit findings and evaluations. Interim report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-01-31

    This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. This report describes a global framework that evaluates spent fuel disposition requirements, influencing factors and strategies. A broad sampling of foreign governmental officials, electric utility spokesmen and nuclear power industry officials responsible for GSFLS policies, plans and programs were surveyed as to their views with respect to national and international GSFLS related considerations. The results of these GSFLS visit findings are presented herein. These findings were then evaluated in terms of technical, institutional and legal/regulatory implications. The GSFLS evaluations, in conjunction with perceived US spent fuel objectives, formed the basis for selecting a set of GSFLS strategies which are reported herein.

  11. The ADVANCE project: Formal evaluation of the targeted deployment. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    ADVANCE [Advanced Driver and Vehicle Advisory Navigation ConcEpt] was a public/private partnership conceived and developed by four founding parties. The founding parties include the Federal Highway Administration (FHWA), the Illinois Department of Transportation (IDOT), the University of Illinois at Chicago and Northwestern University operating together under the auspices of the Illinois Universities Transportation Research Consortium (IUTRC), and Motorola, Inc. The major responsibilities of each party are fully described in the Project agreement. Subsequently, these four were joined on the Steering Committee by the American Automobile Association (AAA). This unique blending of public sector, private sector and university interests, augmented by more than two dozen other private sector participants, provided a strong set of resources for ADVANCE. The ADVANCE test area covered over 300 square miles including portions of the City of Chicago and 40 northwest suburban communities. The Project encompasses the high growth areas adjacent to O`Hare International Airport, the Schaumbura/Hoffman Estates office and retail complexes, and the Lake-Cook Road development corridor. It also includes major sports and entertainment complexes such as the Arlington International Racecourse and the Rosemont Horizon. The population in the area is more than 750,000. This volume provides a summary of the insights and achievements made as a result of this field test, and selected appendices containing more detailed information.

  12. Energy Extension Service Pilot Program: evaluation report after two years. Volume II. State reports

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-04-01

    This report, Vol. II, presents a discussion of the operations of the ten EES pilot state programs during the period from October 1, 1977 through September 30, 1979. Each of the ten pilot states - Alabama, Connecticut, Michigan, New Mexico, Pennsylvania, Tennessee, Texas, Washington, Wisconsin, and Wyoming - received a grant of approximately $1.1 million to develop and implement an 18-month program beginning on October 1, 1977. In September 1978, each State received an additional $370,000 for service-delivery programs for the extension of the pilot program, April 1979 through September 1979. A case-study description of the operations of the pilot program in each State is provided here, with special attention given to the two programs selected in each State for more-detailed study and survey research. Although the thrust of this volume is descriptive, some survey data and analyses are presented for the emphasis programs. Two telephone surveys of clients and a non-client sample were conducted, one at the end of the first year of the pilot program (October 1977 - September 1978) and one at the end of the second year (October 1978 - September 1979).

  13. Evaluation of mean platelet volume in unruptured ectopic pregnancy: A retrospective analysis.

    Science.gov (United States)

    Karaman, Erbil; Çim, Numan; Alkış, İsmet; Yıldızhan, Recep; Elçi, Gülhan

    2016-07-01

    We aimed to investigate and compare the mean platelet volume (MPV) levels in ectopic and viable intrauterine pregnancy (IUP). The medical records of 78 unruptured tubal ectopic pregnancy patients (TEP, Group 1) and 150 patients with viable IUP (Group 2) served as control group between May 2014 and February 2015 in our clinic were retrospectively analysed. The demographic characteristics including age, parity, gravida, abortus, haemoglobin levels and leucocyte counts showed no statistically difference between two groups. The mean MPV level was significantly lower in TEP group compared to IUP group (8.69 ± 1.14 and 10.06 ± 1.46, p < 0.001). The platelet (PLT) distribution width was higher in TEP group, however, there was no statistical difference between the two groups (p = 0.078). The early diagnosis of TEP is crucial in order to prevent maternal morbidity and mortality. Our results showed that MPV is lower in TEP than IUP and it seems to be related with the possible inflammation at implantation site of tuba uterina. However, there is need for further studies for employing PLT indices in the diagnosis of TEP.

  14. Design and evaluation of potentiometric principles for bladder volume monitoring: a preliminary study.

    Science.gov (United States)

    Chen, Shih-Ching; Hsieh, Tsung-Hsun; Fan, Wen-Jia; Lai, Chien-Hung; Chen, Chun-Lung; Wei, Wei-Feng; Peng, Chih-Wei

    2015-06-01

    Recent advances in microelectronics and wireless transmission technology have led to the development of various implantable sensors for real-time monitoring of bladder conditions. Although various sensing approaches for monitoring bladder conditions were reported, most such sensors have remained at the laboratory stage due to the existence of vital drawbacks. In the present study, we explored a new concept for monitoring the bladder capacity on the basis of potentiometric principles. A prototype of a potentiometer module was designed and fabricated and integrated with a commercial wireless transmission module and power unit. A series of in vitro pig bladder experiments was conducted to determine the best design parameters for implementing the prototype potentiometric device and to prove its feasibility. We successfully implemented the potentiometric module in a pig bladder model in vitro, and the error of the accuracy of bladder volume detection was wireless module, the design principles and animal experience gathered from this research can serve as a basis for developing new implantable bladder sensors in the future.

  15. Design and Evaluation of Potentiometric Principles for Bladder Volume Monitoring: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Shih-Ching Chen

    2015-06-01

    Full Text Available Recent advances in microelectronics and wireless transmission technology have led to the development of various implantable sensors for real-time monitoring of bladder conditions. Although various sensing approaches for monitoring bladder conditions were reported, most such sensors have remained at the laboratory stage due to the existence of vital drawbacks. In the present study, we explored a new concept for monitoring the bladder capacity on the basis of potentiometric principles. A prototype of a potentiometer module was designed and fabricated and integrated with a commercial wireless transmission module and power unit. A series of in vitro pig bladder experiments was conducted to determine the best design parameters for implementing the prototype potentiometric device and to prove its feasibility. We successfully implemented the potentiometric module in a pig bladder model in vitro, and the error of the accuracy of bladder volume detection was <±3%. Although the proposed potentiometric device was built using a commercial wireless module, the design principles and animal experience gathered from this research can serve as a basis for developing new implantable bladder sensors in the future.

  16. Feasibility evaluation solar heated textile process water. Volume II. Appendices. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hester, J. C.; Beard, J. N.; Robinson, G. F.; Harnett, R. M.

    1977-02-01

    The general objectives of this study are to determine the technical and economic feasibility of the use of solar energy for heating waters in the textile industry and to develop a plan for efforts beyond this feasibility study phase. Specific objectives include (1) determine the industry requirements for heated process water, (2) assess particular schemes and their economic impact, (3) study the total cost environment for solar water heating in this industry, and (4) recommend future experiments. This volume contains the appendices: (A) fiber distribution and end use data; (B) computer model description for textile plant energy balances; (C) computer model description to generate local solar potential; (D) computer model description for system synthesis and analysis; (E) computer model to determine pressure drop, flow distribution and plumbing components; (F) area requirement plots for various use rates, temperature levels, seasons, orientations and collector types for textile operations; (G) computer model description of economic variables for COSMO1 and COSMO2; (H) rate of return plots for various textile applications and energy cost scenerios; and (I) data base for efficiency curves for six collector types. (WHK)

  17. High-intensity focused ultrasound (HIFU) for pancreatic carcinoma: evaluation of feasibility, reduction of tumour volume and pain intensity.

    Science.gov (United States)

    Marinova, Milka; Rauch, Maximilian; Mücke, Martin; Rolke, Roman; Gonzalez-Carmona, Maria A; Henseler, Jana; Cuhls, Henning; Radbruch, Lukas; Strassburg, Christian P; Zhang, Lian; Schild, Hans H; Strunk, Holger M

    2016-11-01

    Prognosis of patients with locally advanced pancreatic adenocarcinoma is extremely poor. They often suffer from cancer-related pain reducing their quality of life. This prospective observational study aimed to evaluate feasibility, local tumour response, and changes in quality of life and symptoms in Caucasian patients with locally advanced pancreatic cancer treated by ultrasound-guided high-intensity focused ultrasound (HIFU). Thirteen patients underwent HIFU, five with stage III, eight with stage IV UICC disease. Ten patients received simultaneous palliative chemotherapy. Postinterventional clinical assessment included evaluation of quality of life and symptom changes using standardized questionnaires. CT and MRI follow-up evaluated the local tumour response. HIFU was successfully performed in all patients. Average tumour reduction was 34.2 % at 6 weeks and 63.9 % at 3 months. Complete or partial relief of cancer-related pain was achieved in 10 patients (77 %), five of whom required less analgesics for pain control. Quality of life was improved revealing increased global health status and alleviated symptoms. HIFU treatment was well tolerated. Eight patients experienced transient abdominal pain directly after HIFU. HIFU ablation of pancreatic carcinoma is a feasible, safe and effective treatment with a crucial benefit in terms of reduction of tumour volume and pain intensity. • US-guided HIFU is feasible and safe for patients with unresectable pancreatic cancer. • HIFU can considerably reduce tumour volume and cancer-related pain. • Patients treated with HIFU experienced significant and lasting reduction of pain intensity. • HIFU has a crucial clinical benefit for patients with pancreatic cancer.

  18. OTEC modular experiment: cold water pipe concept evaluation. Volume II. Technical report

    Energy Technology Data Exchange (ETDEWEB)

    1979-04-01

    The Cold Water Pipe System Design Study was undertaken to evaluate the diverse CWP concepts, recommend the most viable alternatives for a 1984 deployment of the 10 to 40 MWe MEP, and carry out preliminary designs of three concepts. The Concept Evaluation Phase reported here involved a systems analysis of design alternatives in the broad categories of rigid walled (with hinges), compliant walled, stockade and bottom mounted buoyant. Quantitative evaluations were made of concept performance, availability, deployment schedule, technical feasibility and cost. CWP concepts were analyzed to determine if they met or could be made to meet established system requirements and could be deployed by 1984. Those which faced overwhelming technical and/or scheduling problems were rejected. Those which were unviable due to isolated, crucial technical and/or scheduling problems for which a technical development may reverse the decisions were deferred. Fabrication, construction and installation plans were developed for successful concepts, and costs were determined in a WBS format. Evaluations were performed on the basis of technical and cost risk. (WHK)

  19. Indian Economic Development: An Evaluation of EDA's Selected Indian Reservation Program. Volume I: Narrative.

    Science.gov (United States)

    Boise Cascade Center for Community Development, ID.

    The Selected Indian Reservation Program established under the Economic Development Administration in 1967 was evaluated in terms of actual or potential job creation via detailed assessment of EDA activities on 16 reservations, discussions at the regional and national levels of EDA program tools (public work grants/loans, business development…

  20. 1992-1993 Bonneville Appliance Efficiency Program: Showerhead evaluation. Volume I - report

    Energy Technology Data Exchange (ETDEWEB)

    Warwick, W.M.

    1995-01-01

    The Bonneville Power Administration (Bonneville) provides wholesale electric power to over 100 retail distribution utilities in the Pacific Northwest. Bonneville is faced with meeting growing loads from these utilities. It acquires conservation as one means of meeting this load growth. Bonneville has offered a variety of conservation programs since 1980. Efficient showerheads have been a feature in residential conservation programs ever since. Bonneville launched the Residential Appliance Efficiency Program to focus on water-heater energy conservation opportunities in 1992. The Residential Appliance Efficiency Program consists of two parts, a water-heater efficiency program, and a hot-water efficiency program. This report evaluates the savings and costs of the first two years of the showerhead portion of the Residential Appliance Efficiency Program (the showerhead program). Although it is not a formal evaluation of the program limited to implementation or a {open_quotes}process{close_quotes} evaluation, observations about program design and implementation are included as appropriate. Results of this evaluation are limited to program participants within the Bonneville service territory.

  1. National Uranium Resource Evaluation. Volume 1. Summary of the geology and uranium potential of Precambrian conglomerates in southeastern Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    Karlstrom, K.E.; Houston, R.S.; Flurkey, A.J.; Coolidge, C.M.; Kratochvil, A.L.; Sever, C.K.

    1981-02-01

    A series of uranium-, thorium-, and gold-bearing conglomerates in Late Archean and Early Proterozoic metasedimentary rocks have been discovered in southern Wyoming. The mineral deposits were found by applying the time and strata bound model for the origin of uranium-bearing quartz-pebble conglomerates to favorable rock types within a geologic terrane known from prior regional mapping. No mineral deposits have been discovered that are of current (1981) economic interest, but preliminary resource estimates indicate that over 3418 tons of uranium and over 1996 tons of thorium are present in the Medicine Bow Mountains and that over 440 tons of uranium and 6350 tons of thorium are present in Sierra Madre. Sampling has been inadequate to determine gold resources. High grade uranium deposits have not been detected by work to date but local beds of uranium-bearing conglomerate contain as much as 1380 ppM uranium over a thickness of 0.65 meters. This project has involved geologic mapping at scales from 1/6000 to 1/50,000 detailed sampling, and the evaluation of 48 diamond drill holes, but the area is too large to fully establish the economic potential with the present information. This first volume summarizes the geologic setting and geologic and geochemical characteristics of the uranium-bearing conglomerates. Volume 2 contains supporting geochemical data, lithologic logs from 48 drill holes in Precambrian rocks, and drill site geologic maps and cross-sections from most of the holes. Volume 3 is a geostatistical resource estimate of uranium and thorium in quartz-pebble conglomerates.

  2. Evaluation of the relationship between renal function and renal volume-vascular indices using 3D power Doppler ultrasound

    Energy Technology Data Exchange (ETDEWEB)

    Cansu, Aysegul, E-mail: drcansu@gmail.com; Kupeli, Ali; Kul, Sibel; Eyuboglu, Ilker; Oguz, Sukru; Ozturk, Mehmet Halil; Dinc, Hasan

    2014-07-15

    Purpose: To investigate the relationship between renal function and total renal volume-vascular indices using 3D power Doppler ultrasound (3DPDUS). Materials and methods: One hundred six patients with hypertensive proteinuric nephropathy (HPN) (49 male, 57 female) and 65 healthy controls (32 male, 33 female) were evaluated prospectively using 3DPDUS. Total renal volume (RV), vascularization index (VI), flow index (FI) and vascularization flow index (VFI) were calculated using Virtual Organ Computer-aided Analysis (VOCAL). The estimated glomerular filtration rates (GFRs) of the patients with HPN and the control group were calculated. The patients with HPN were divided into two groups on the basis of GFR, normal (≥90) or reduced (<90). Differences between groups were compared using ANOVA. Correlations between GFR, renal volume and vascular indices were analyzed using Pearson's correlation analysis. Significance was set at p < 0.05. Results: The mean total RV, VI, FI and VFI values in the reduced GFR, normal GFR and control groups were RV (ml): 234.7, 280.7 and 294.6; VI: 17.6, 27.6 and 46.8; FI: 79.1, 88.7 and 93.9 and VFI: 7.1, 12.7 and 23.8. There were statistically significant differences between the groups (p < 0.001). Total RVs and vascular indices exhibited significant correlations with estimated GFR (r = 0.53–0.59, p < 0.001) Conclusion: Three-dimensional power Doppler ultrasound is a reliable predictive technique in renal function analysis.

  3. BPACK -- A computer model package for boiler reburning/co-firing performance evaluations. User`s manual, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Wu, K.T.; Li, B.; Payne, R.

    1992-06-01

    This manual presents and describes a package of computer models uniquely developed for boiler thermal performance and emissions evaluations by the Energy and Environmental Research Corporation. The model package permits boiler heat transfer, fuels combustion, and pollutant emissions predictions related to a number of practical boiler operations such as fuel-switching, fuels co-firing, and reburning NO{sub x} reductions. The models are adaptable to most boiler/combustor designs and can handle burner fuels in solid, liquid, gaseous, and slurried forms. The models are also capable of performing predictions for combustion applications involving gaseous-fuel reburning, and co-firing of solid/gas, liquid/gas, gas/gas, slurry/gas fuels. The model package is conveniently named as BPACK (Boiler Package) and consists of six computer codes, of which three of them are main computational codes and the other three are input codes. The three main codes are: (a) a two-dimensional furnace heat-transfer and combustion code: (b) a detailed chemical-kinetics code; and (c) a boiler convective passage code. This user`s manual presents the computer model package in two volumes. Volume 1 describes in detail a number of topics which are of general users` interest, including the physical and chemical basis of the models, a complete description of the model applicability, options, input/output, and the default inputs. Volume 2 contains a detailed record of the worked examples to assist users in applying the models, and to illustrate the versatility of the codes.

  4. Partial volume rat lung irradiation: an evaluation of early DNA damage.

    Science.gov (United States)

    Khan, M A; Hill, R P; Van Dyk, J

    1998-01-15

    1. To investigate early DNA damage induced in rat lung cells following single-dose, partial-volume irradiation (lung base and lung apex). 2. To determine the variation in DNA damage in different lung regions. 3. To investigate the possible mechanisms associated with early DNA damage after lung irradiation. The whole lung or the upper or lower half of the entire lung of Sprague-Dawley rats was exposed to 10 Gy 60Co gamma rays. The animals were sacrificed at various times up to 42 h after irradiation. A trypsin-digested lung cell suspension was prepared and cells that attached to slides in the initial 24-h period were then grown in the presence of culture medium with cytochalasin-B for a further 72 h. Radiation-induced DNA damage was quantified in the cells (primarily fibroblasts) from both irradiated and unirradiated lung regions by using a well-characterized micronucleus assay. When the lungs were removed at 16-18 h after whole-lung irradiation, about 0.85 micronuclei (MN) per binucleate cell (BNC) were observed in the lung cells of the irradiated animals, compared to 0.02 MN/BNC in the lung cells of the controls. When only the lung base was irradiated, the frequency of micronuclei was 0.85 MN/BNC compared to 0.43 MN/BNC observed in cells from the irradiated lung apex. Of particular interest was the finding that the unirradiated lung apex also showed a large frequency of micronuclei (0.43 MN/BNC) after the irradiation of the lung base, whereas the unirradiated lung base showed only a marginal (approximately 2-fold) increase relative to the spontaneous frequency following irradiation of the lung apex. The changes in the frequency of micronuclei varied with the time at which the lungs were removed from the rats for early times, but had stabilized by 18 h after irradiation. Normal (unirradiated) cells grown in filtered or unfiltered conditioned media obtained from irradiated cell cultures showed an insignificant marginal increase in the number of micronuclei relative

  5. Evaluation of two-phase flow solvers using Level Set and Volume of Fluid methods

    Science.gov (United States)

    Bilger, C.; Aboukhedr, M.; Vogiatzaki, K.; Cant, R. S.

    2017-09-01

    Two principal methods have been used to simulate the evolution of two-phase immiscible flows of liquid and gas separated by an interface. These are the Level-Set (LS) method and the Volume of Fluid (VoF) method. Both methods attempt to represent the very sharp interface between the phases and to deal with the large jumps in physical properties associated with it. Both methods have their own strengths and weaknesses. For example, the VoF method is known to be prone to excessive numerical diffusion, while the basic LS method has some difficulty in conserving mass. Major progress has been made in remedying these deficiencies, and both methods have now reached a high level of physical accuracy. Nevertheless, there remains an issue, in that each of these methods has been developed by different research groups, using different codes and most importantly the implementations have been fine tuned to tackle different applications. Thus, it remains unclear what are the remaining advantages and drawbacks of each method relative to the other, and what might be the optimal way to unify them. In this paper, we address this gap by performing a direct comparison of two current state-of-the-art variations of these methods (LS: RCLSFoam and VoF: interPore) and implemented in the same code (OpenFoam). We subject both methods to a pair of benchmark test cases while using the same numerical meshes to examine a) the accuracy of curvature representation, b) the effect of tuning parameters, c) the ability to minimise spurious velocities and d) the ability to tackle fluids with very different densities. For each method, one of the test cases is chosen to be fairly benign while the other test case is expected to present a greater challenge. The results indicate that both methods can be made to work well on both test cases, while displaying different sensitivity to the relevant parameters.

  6. Final Report, Volume 1, Metallurgical Evaluation of Cast Duplex Stainless Steels and their Weldments

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Songqing; Lundin, Carl, W.; Batten, Greg, W.

    2005-09-30

    Duplex stainless steels (DSS) are being specified for chloride containing environments due to their enhanced pitting and stress corrosion cracking resistance. They exhibit improved corrosion performance over the austenitic stainless steels. Duplex stainless steels also offer improved strength properties and are available in various wrought and cast forms. Selected grades of duplex stainless steel castings and their welds, in comparison with their wrought counterparts, were evaluated, regarding corrosion performance and mechanical properties and weldability. Multiple heats of cast duplex stainless steel were evaluated in the as-cast, solution annealed (SA) static cast and SA centrifugal cast conditions, while their wrought counterparts were characterized in the SA condition and in the form of as-rolled plate. Welding, including extensive assessment of autogenous welds and a preliminary study of composite welds (shielded metal arc weld (SMAW)), was performed. The evaluations included critical pitting temperature (CPT) testing, intergranular corrosion (IGC) testing, ASTM A923 (Methods A, B and C), Charpy impact testing, weldability testing (ASTM A494), ferrite measurement and microstructural evaluations. In the study, the corrosion performances of DSS castings were characterized and assessed, including the wrought counterparts for comparison. The evaluation filled the pore of lack of data for cast duplex stainless steels compared to wrought materials. A database of the pitting corrosion and IGC behavior of cast and wrought materials was generated for a greater depth of understanding for the behavior of cast duplex stainless steel. In addition, improved evaluation methods for DSS castings were developed according to ASTM A923, A262, G48 and A494. The study revealed that when properly heat treated according to the specification, (1) DSS castings have equal or better pitting and intergranular corrosion resistance than their wrought counterparts; (2) Welding reduces the

  7. Final Report, Volume 1, Metallurgical Evaluation of Cast Duplex Stainless Steels and their Weldments

    Energy Technology Data Exchange (ETDEWEB)

    Wen, Songqing; Lundin, Carl, W.; Batten, Greg, W.

    2005-09-30

    Duplex stainless steels (DSS) are being specified for chloride containing environments due to their enhanced pitting and stress corrosion cracking resistance. They exhibit improved corrosion performance over the austenitic stainless steels. Duplex stainless steels also offer improved strength properties and are available in various wrought and cast forms. Selected grades of duplex stainless steel castings and their welds, in comparison with their wrought counterparts, were evaluated, regarding corrosion performance and mechanical properties and weldability. Multiple heats of cast duplex stainless steel were evaluated in the as-cast, solution annealed (SA) static cast and SA centrifugal cast conditions, while their wrought counterparts were characterized in the SA condition and in the form of as-rolled plate. Welding, including extensive assessment of autogenous welds and a preliminary study of composite welds (shielded metal arc weld (SMAW)), was performed. The evaluations included critical pitting temperature (CPT) testing, intergranular corrosion (IGC) testing, ASTM A923 (Methods A, B and C), Charpy impact testing, weldability testing (ASTM A494), ferrite measurement and microstructural evaluations. In the study, the corrosion performances of DSS castings were characterized and assessed, including the wrought counterparts for comparison. The evaluation filled the pore of lack of data for cast duplex stainless steels compared to wrought materials. A database of the pitting corrosion and IGC behavior of cast and wrought materials was generated for a greater depth of understanding for the behavior of cast duplex stainless steel. In addition, improved evaluation methods for DSS castings were developed according to ASTM A923, A262, G48 and A494. The study revealed that when properly heat treated according to the specification, (1) DSS castings have equal or better pitting and intergranular corrosion resistance than their wrought counterparts; (2) Welding reduces the

  8. Evaluation of respiratory volume monitoring (RVM) to detect respiratory compromise in advance of pulse oximetry and help minimize false desaturation alarms.

    Science.gov (United States)

    Galvagno, Samuel M; Duke, Peggy G; Eversole, Daniel S; George, Edward E

    2016-11-01

    Monitoring respiratory function is important. By continuously monitoring respiratory volumes, respiratory depression could be identified before hypoxemia and drive earlier intervention. Here, we evaluate the temporal relationship of respiratory volume monitoring (providing real-time minute ventilation [MV], tidal volume, and respiratory rate in nonintubated patients) to hypoxemic episodes and its potential to help classify true vs false desaturations (related to patient movement/probe dislodgement). Respiratory volume monitoring data, oxygen saturation (SpO2), oxygen supplementation, and opioid use were analyzed in 259 patients following orthopedic surgery. Detection of "low MV" (monitoring can provide advanced warning of impending oxygen desaturation and potentially reduce the number of false SpO2 alarms. Opioid administration increased low MV events correlating with increased LOS. Respiratory volume monitoring can help clinicians individualize patient care, decrease false alarms, adjust opioid dosing, and increase PACU throughput. Similar benefits may translate to the general care floor and prehospital and posthospital environments. Diagnostic study, level II.

  9. 1992-1993 Bonneville Appliance Efficiency Program: Showerhead Evaluation Volume II - Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Warwick, W.M.

    1995-01-01

    This report included the appendices for 1992-1993 Bonneville appliance efficiency program: showerhead evaluation. It consists of nine appendices, titled: Bonneville documents; overview of research projects; Puget Power and Light persistence study; hot-water flow analyses and assumptions documentation; regional end-use metering program; showerhead and faucet aerator performance assessment; Bonneville showerhead program distribution methods by participating utility; water- and energy-saving measure distribution methods literature review; REMP study load shape results.

  10. Handbook for Evaluation and Life Cycle Planning for Software. Volume 2. Contract Management.

    Science.gov (United States)

    1983-02-01

    Pights in Technical Data and Computer Software, Direct Licensing or Technical Additional SubjeCt to EQuitable Adjustment in Price" and CLIN YYYY...plus criteria ana schedule for proposal evaluation and co:tractor selection. .nz3ure Ordt complies witn PMP directions regarding source selection...System Engineer3" Are the assistant lead programmers staffed by MA degrees - Copvte. Scince . and !,elated fields with 5 or more years experience? Are the

  11. Evaluation of PET volume segmentation methods: comparisons with expert manual delineations.

    Science.gov (United States)

    Dewalle-Vignion, Anne-Sophie; Yeni, Nathanaëlle; Petyt, Grégory; Verscheure, Leslie; Huglo, Damien; Béron, Amandine; Adib, Salim; Lion, Georges; Vermandel, Maximilien

    2012-01-01

    [¹⁸F]-Fluorodeoxyglucose PET has become an essential technique in oncology. Accurate segmentation is important for treatment planning. With the increasing number of available methods, it will be useful to establish a reliable evaluation tool. Five methods for [F]-fluorodeoxyglucose PET image segmentation (MIP-based, Fuzzy C-means, Daisne, Nestle and the 42% threshold-based approach) were evaluated on non-Hodgkin's lymphoma lesions by comparing them with manual delineations performed by a panel of experts. The results were analyzed using different similarity measures. Intraoperator and interoperator variabilities were also studied. The maximum of intensity projection-based method provided results closest to the manual delineations set [binary Jaccard index mean (SD) 0.45 (0.15)]. The fuzzy C-means algorithm yielded slightly less satisfactory results. The application of a 42% threshold-based approach yielded results furthest from the manual delineations [binary Jaccard index mean (SD) 0.38 (0.16)]; the Daisne and the Nestle methods yielded intermediate results. Important intraoperator and interoperator variabilities were demonstrated. A simple assessment framework based on comparisons with manual delineations was proposed. The use of a set of manual delineations performed by five different experts as the reference seemed to be suitable to take the intraoperator and the interoperator variabilities into account. The online distribution of the data set generated in this study will make it possible to evaluate any new segmentation method.

  12. Coal liquefaction process streams characterization and evaluation. Volume 1, Base program activities

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, G.A.; Brandes, S.D.; Winschel, R.A.; Burke, F.P.

    1994-05-01

    This 4.5-year project consisted of routine analytical support to DOE`s direct liquefaction process development effort (the Base Program), and an extensive effort to develop, demonstrate, and apply new analytical methods for the characterization of liquefaction process streams (the Participants Program). The objective of the Base Program was to support the on-going DOE direct coal liquefaction process development program. Feed, process, and product samples were used to assess process operations, product quality, and the effects of process variables, and to direct future testing. The primary objective of the Participants Program was to identify and demonstrate analytical methods for use in support of liquefaction process development, and in so doing, provide a bridge between process design, and development, and operation and analytical chemistry. To achieve this objective, novel analytical methods were evaluated for application to direct coal liquefaction-derived materials. CONSOL teamed with 24 research groups in the program. Well-defined and characterized samples of coal liquefaction process-derived materials were provided to each group. CONSOL made an evaluation of each analytical technique. During the performance of this project, we obtained analyses on samples from numerous process development and research programs and we evaluated a variety of analytical techniques for their usefulness in supporting liquefaction process development. Because of the diverse nature of this program, we provide here an annotated bibliography of the technical reports, publications, and formal presentations that resulted from this program to serve as a comprehensive summary of contract activities.

  13. Preliminary evaluation of crisis-relocation fallout-shelter options. Volume 2. Detailed analysis

    Energy Technology Data Exchange (ETDEWEB)

    Santini, D.J.; Clinch, J.M.; Davis, F.H.; Hill, L.G.; Lynch, E.P.; Tanzman, E.A.; Wernette, D.R.

    1982-12-01

    This report presents a preliminary, detailed evaluation of various shelter options for use if the President orders crisis relocation of the US urban population because of strong expectation of a nuclear war. The availability of livable shelter space at 40 ft/sup 2/ per person (congregate-care space) by state is evaluated. Options are evaluated for construction of fallout shelters allowing 10 ft/sup 2/ per person - such shelters are designed to provide 100% survival at projected levels of radioactive fallout. The FEMA concept of upgrading existing buildings to act as fallout shelters can, in principle, provide adequate shelter throughout most of the US. Exceptions are noted and remedies proposed. In terms of upgrading existing buildings to fallout shelter status, great benefits are possible by turning away from a standard national approach and adopting a more site-specific approach. Existing FEMA research provides a solid foundation for successful crisis relocation planning, but the program can be refined by making suitable modifications in its locational, engineering, and institutionally specific elements.

  14. Avaliação cronológica da variação no volume globular sanguíneo de bovinos leiteiros Cronological evaluation of variation in packed cell volume on dairy cattle

    Directory of Open Access Journals (Sweden)

    Wilmar Sachetin Marçal

    1995-01-01

    Full Text Available Os autores avaliaram a variação no volume globular sangüíneo de 321 bovinos da raça Holandês preta e branca, sadios e criados em granjas leiteiras no Estado de São Paulo. Todos os animais trabalhados na presente pesquisa eram sadios, não reagentes ao vírus da Leucose Bovina, livres de hemoparasitas, brucelose e tuberculose. O volume globular sangüíneo foi efetuado através do método do hematócrito com tubos capilares. Os resultados mostram haver influência da idade sobre o volume globular sangüíneo, com valores médios encontrados de 30,12 ± 2,72%.The packet cell volume was evaluated by the authors in 321 healthy female Holstein cattle raised at Campinas dairy region. São Paulo State. All the animais used in this assay were healthy and free of Leucosis, Tuberculosis, Brucellosis and blood parasites. The packed cell volume has been studied by method of hematocrit with capilary tubos. The results showed an influence of age on packed cell volume with average reference values of 30.12 ± 2.72%.

  15. Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA.

    Science.gov (United States)

    Keeshan, Karen; Vieugué, Pauline; Chaudhury, Shahzya; Rishi, Loveena; Gaillard, Coline; Liang, Lu; Garcia, Elaine; Nakamura, Takuro; Omidvar, Nader; Kogan, Scott C

    2016-10-01

    The PML/RARA fusion protein occurs as a result of the t(15;17) translocation in the acute promyelocytic leukemia subtype of human acute myeloid leukemia. Gain of chromosome 8 is the most common chromosomal gain in human acute myeloid leukemia, including acute promyelocytic leukemia. We previously demonstrated that gain of chromosome 8-containing MYC is of central importance in trisomy 8, but the role of the nearby TRIB1 gene has not been experimentally addressed in this context. We have now tested the hypothesis that both MYC and TRIB1 have functional roles underlying leukemogenesis of trisomy 8 by using retroviral vectors to express MYC and TRIB1 in wild-type bone marrow and in marrow that expressed a PML/RARA transgene. Interestingly, although MYC and TRIB1 readily co-operated in leukemogenesis for wild-type bone marrow, TRIB1 provided no selective advantage to cells expressing PML/RARA. We hypothesized that this lack of co-operation between PML/RARA and TRIB1 reflected a common pathway for their effect: both proteins targeting the myeloid transcription factor C/EBPα. In support of this idea, TRIB1 expression abrogated the all-trans retinoic acid response of acute promyelocytic leukemia cells in vitro and in vivo Our data delineate the common and redundant inhibitory effects of TRIB1 and PML/RARA on C/EBPα providing a potential explanation for the lack of selection of TRIB1 in human acute promyelocytic leukemia, and highlighting the key role of C/EBPs in acute promyelocytic leukemia pathogenesis and therapeutic response. In addition, the co-operativity we observed between MYC and TRIB1 in the absence of PML/RARA show that, outside of acute promyelocytic leukemia, gain of both genes may drive selection for trisomy 8. Copyright© Ferrata Storti Foundation.

  16. Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification.

    Directory of Open Access Journals (Sweden)

    Robert E White

    2010-11-01

    Full Text Available Epstein-Barr virus (EBV is able to drive the transformation of B-cells, resulting in the generation of lymphoblastoid cell lines (LCLs in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of BL31 cells infected with a series of EBNA3-knockout EBVs, including one deleted for all three EBNA3 genes. Using Affymetrix Exon 1.0 ST microarrays analysed with the MMBGX algorithm, we have identified over 1000 genes whose regulation by EBV requires one of the EBNA3s. Remarkably, a third of the genes identified require more than one EBNA3 for their regulation, predominantly EBNA3C co-operating with either EBNA3B, EBNA3A or both. The microarray was validated by real-time PCR, while ChIP analysis of a selection of co-operatively repressed promoters indicates a role for polycomb group complexes. Targets include genes involved in apoptosis, cell migration and B-cell differentiation, and show a highly significant but subtle alteration in genes involved in mitosis. In order to assess the relevance of the BL31 system to LCLs, we analysed the transcriptome of a set of EBNA3B knockout (3BKO LCLs. Around a third of the genes whose expression level in LCLs was altered in the absence of EBNA3B were also altered in 3BKO-BL31 cell lines.Among these are TERT and TCL1A, implying that EBV-induced changes in the expression of these genes are not required for B-cell transformation. We also identify 26 genes that require both EBNA3A and EBNA3B for their regulation in LCLs. Together, this shows the complexity of the interaction between EBV and its host, whereby multiple EBNA3 proteins co-operate to modulate the behaviour of the host cell.

  17. Co-operation between Large Enterprises (LE’s and SME’s: an Approach to Overcome the Stage Internationalization Process

    Directory of Open Access Journals (Sweden)

    Eurico Brilhante Dias

    2014-12-01

    Full Text Available Many companies are using their networks in order to overcome psychic distance – liability of foreignness – and liability of outsidership; and networks at domestic markets can be a base in which SMEs can find a lever to get a rapid internationalization process. Regarding this topic has been developed a case study in the Polish market, where a local retailer (“Biedronka” owned by a Portuguese group (“Jerónimo Martins” is offering Portuguese products. In order to apply a constructivist methodology, using the case study method, five SMEs where selected in order to understand if co-operation between these companies and a LE (Large Enterprise would be a way in order to overcome the liability of foreignness and the liability of outsidership. It was also our purpose the understanding of which are the main issues that promote insidership and also the promotion of a rapid internationalization. Our conclusions have shown a LE as a source of institutional and market-specific knowledge, and regarding this last type of knowledge, as source of opportunities, and also how a SME with internationalization knowledge, an international focus and adaptation skills (in order to adapt products and prices can introduce in a co-operative international venture, in far psychic markets, the ingredients needed to get a successful and rapid entry in a foreign market. Trust as a resource, accumulated during lasting relationships in the domestic market, has been shown as a basic requirement to develop these co-operative approaches in international markets.

  18. Theoretical Foundations of the Web: Cognition, Communication, and Co-Operation. Towards an Understanding of Web 1.0, 2.0, 3.0

    OpenAIRE

    Robert Bichler; Marisol Sandoval; Celina Raffl; Matthias Schafranek; Wolfgang Hofkirchner; Christian Fuchs

    2010-01-01

    Currently, there is much talk of Web 2.0 and Social Software. A common understanding of these notions is not yet in existence. The question of what makes Social Software social has thus far also remained unacknowledged. In this paper we provide a theoretical understanding of these notions by outlining a model of the Web as a techno-social system that enhances human cognition towards communication and co-operation. According to this understanding, we identify three qualities of the Web, namely...

  19. H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development

    CERN Multimedia

    Maximilien Brice

    2002-01-01

    H.S.H. Prince Radu of Hohenzollern-Veringen, Special Representative of the Romanian Government for Integration, Co-operation and Sustainable Development, is seen here visiting Microcosm, CERN's on-site exhibition centre. Photo 01: H.S.H. Prince Radu of Hohenzollern-Veringen (right) with his personal adviser Cornel Comsa inside Microcosm's full-scale model of a six-metre section of the LHC. Photos 04-06: H.S.H. Prince Radu of Hohenzollern-Veringen with Emma Sanders from ETT Division.

  20. Evaluation and Validation (E&V) Team Public Report. Volume 2.

    Science.gov (United States)

    1985-11-30

    digits beginning in "DEC-83" and continuing at three month intervals. A hardcopy of the minutes will also be incorporated in the annual E&V Team...letters, YEAR being two digits , beginning in "DEC-83" and continuing at three month intervals. Minutes of the EVALUATION & Validation (E&V) MEETING Date I...CPU’s), 262 terminals (with 132 more on order), and 160 bus interface units. The SPS also includes two IDM 500 Data Base Machines, 6 Imagen laser

  1. Evaluation and Validation (E&V) Team Public Report. Volume 5

    Science.gov (United States)

    1990-10-31

    Mr. Jeff Facemire, SPC (formerly SofTech Houston) Mr. Jack Foidl, TRW San Deigo Mr. Kurt Gutzmann, SofTech Houston Mr. Kevin Hackett, SofTech San...occurrence. 10) P.19, 3rd para. "Those that have made the extra effort...". How will the evaluation reward these " goodies ". 11) P.21, program segment...Lindquist Jeff Facemire Tracy Holmes Lloyd Stiles John McBride Shawn Fanning Jack Foidl Guests in attendance were: Ray Szymanski, Ronnie Martin, and Denise

  2. More than Just the Number of Brain Metastases: Evaluating the Impact of Brain Metastasis Location and Relative Volume on Overall Survival After Stereotactic Radiosurgery.

    Science.gov (United States)

    Emery, Ashley; Trifiletti, Daniel M; Romano, Kara D; Patel, Nirav; Smolkin, Mark E; Sheehan, Jason P

    2017-03-01

    Most evidence describing outcomes of patients with brain metastases is based on number of brain metastases, rather than location or volume. We evaluated the impact of tumor location and relative volume on overall survival (OS) among a large cohort of patients treated with stereotactic radiosurgery. Clinical, radiographic, and dosimetric data were collected on patients treated with first (if multiple) stereotactic radiosurgery for brain metastases. Multivariate analyses were performed to investigate the impact of brain metastasis relative location and volume on OS after stereotactic radiosurgery. Analysis included 300 patients with 817 tumors (116 patients with single brain metastasis). The most common tumor locations were supratentorial (75% of tumors), cerebellar (19%), and brainstem (5%). Median tumor volume was 0.4 mL (range, 0.003-65.0 mL). Tumor-specific factors associated with inferior OS included brainstem location versus both supratentorial and cerebellum locations for particular assumed values of cube root tumor volume (P < 0.001 for each) and increasing total supratentorial tumor volume (P = 0.004). Patients with supratentorial tumors and cerebellar tumors demonstrated similar OS, and cube root total tumor volume within the cerebellum and brainstem did not predict for OS. The presence of brainstem metastases and cumulative supratentorial tumor volume are adverse features that result in inferior survival. These results can be used to inform patient prognosis and future clinical trial design. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Oak Ridge K-25 Site Technology Logic Diagram. Volume 3, Technology evaluation data sheets; Part B, Remedial action, robotics/automation, waste management

    Energy Technology Data Exchange (ETDEWEB)

    Fellows, R.L. [ed.

    1993-02-26

    The Oak Ridge K-25 Technology Logic Diagram (TLD), a decision support tool for the K-25 Site, was developed to provide a planning document that relates environmental restoration (ER) and waste management (WN) problems at the Oak Ridge K-25 Site. The TLD technique identifies the research necessary to develop these technologies to a state that allows for technology transfer and application to waste management, remediation, decontamination, and decommissioning activities. The TLD consists of four separate volumes-Vol. 1, Vol. 2, Vol. 3A, and Vol. 3B. Volume 1 provides introductory and overview information about the TLD. Volume 2 contains logic diagrams. Volume 3 has been divided into two separate volumes to facilitate handling and use. This volume 3 B provides the Technology Evaluation Data Sheets (TEDS) for ER/WM activities (Remedial Action Robotics and Automation, Waste Management) that are referenced by a TEDS code number in Vol. 2 of the TLD. Each of these sheets represents a single logic trace across the TLD. These sheets contain more detail than each technology in Vol. 2. The TEDS are arranged alphanumerically by the TEDS code number in the upper right corner of each data sheet. Volume 3 can be used in two ways: (1) technologies that are identified from Vol. 2 can be referenced directly in Vol. 3 by using the TEDS codes, and (2) technologies and general technology areas (alternatives) can be located in the index in the front of this volume.

  4. Quantitative evaluation of masseter muscle volume in different growth patterns and its correlation with facial morphology: Cone beam computed tomography study

    OpenAIRE

    Mukesh Gupta; P G Makhija

    2016-01-01

    Objective: This investigation was designed to evaluate the masseter muscle volume in different growth patterns and its correlation with facial morphology using three-dimensional cone beam computed tomography (CBCT), Materials and Methods: Study was conducted using CBCT scans of nonorthodontically treated individuals (n = 32, 19 males and 13 females) between the ages of 18–25 years. The masseter muscle volume was calculated using Dolphin 3D software 11.5 version (Essential Dental Products, New...

  5. Occupant evaluation of commercial office lighting: Volume 1, Methodology and bibliography

    Energy Technology Data Exchange (ETDEWEB)

    Brown, M.A. (ed.)

    1986-11-01

    This report documents the forms and procedures developed for a post-occupancy evaluation of office lighting environments. It is the first in a series of four reports. The central aim of the larger project is to explore possible causal factors that are associated with successful lighting design, with particular interest in the relationship between the connected lighting power load and subjective measures of lighting quality. A post-occupancy evaluation procedure was used as the strategy for obtaining the desired data. The procedure involved collecting several different types of data: (1) direct measures of the physical environment, including spatial luminances, illuminances and contrast conditions; (2) indirect measures such as the amount of space provided for each work station and the connected lighting power load; (3) occupant responses to lighting and other factors of the work station; and (4) a limited number of expert ratings of the lighting conditions. Data from thirteen buildings and 1217 work stations were collected. These data were built into a database allowing lighting quality to be quantified and explained.

  6. Human factors evaluation of teletherapy: Identification of problems and alternative approaches. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Henriksen, K.; Kaye, R.D.; Jones, R. [Hughes Training, Inc., Falls Church, VA (United States); Morisseau, D.S.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-07-01

    A series of human factors evaluations was undertaken to better understand the contributing factors to human error in the teletherapy environment. Teletherapy is a multi-disciplinary methodology for treating cancerous tissue through selective exposure to an external beam of ionizing radiation. The principal sources of radiation are a radioactive isotope, typically cobalt60 (Co-60), or a linear accelerator device capable of producing very high energy x-ray and electron beams. A team of human factors specialists, assisted by a panel of radiation oncologists, medical physicists, and radiation technologists, conducted site visits to radiation oncology departments at community hospitals, university centers, and free-standing clinics. A function and task analysis was initially performed to guide subsequent evaluations in the areas of user-system interfaces, procedures, training and qualifications, and organizational policies and practices. The final phase of the project focused on identification of the most significant human factors problems with respect to safe and effective operation of the teletherapy system and an identification and assessment of alternative approaches for resolving the problems. This report presents the findings of this final phase.

  7. Evaluation of semiconductor devices for Electric and Hybrid Vehicle (EHV) ac-drive applications, volume 1

    Science.gov (United States)

    Lee, F. C.; Chen, D. Y.; Jovanovic, M.; Hopkins, D. C.

    1985-01-01

    The results of evaluation of power semiconductor devices for electric hybrid vehicle ac drive applications are summarized. Three types of power devices are evaluated in the effort: high power bipolar or Darlington transistors, power MOSFETs, and asymmetric silicon control rectifiers (ASCR). The Bipolar transistors, including discrete device and Darlington devices, range from 100 A to 400 A and from 400 V to 900 V. These devices are currently used as key switching elements inverters for ac motor drive applications. Power MOSFETs, on the other hand, are much smaller in current rating. For the 400 V device, the current rating is limited to 25 A. For the main drive of an electric vehicle, device paralleling is normally needed to achieve practical power level. For other electric vehicle (EV) related applications such as battery charger circuit, however, MOSFET is advantageous to other devices because of drive circuit simplicity and high frequency capability. Asymmetrical SCR is basically a SCR device and needs commutation circuit for turn off. However, the device poses several advantages, i.e., low conduction drop and low cost.

  8. Human factors evaluation of remote afterloading brachytherapy. Volume 2, Function and task analysis

    Energy Technology Data Exchange (ETDEWEB)

    Callan, J.R.; Gwynne, J.W. III; Kelly, T.T.; Muckler, F.A. [Pacific Science and Engineering Group, San Diego, CA (United States); Saunders, W.M.; Lepage, R.P.; Chin, E. [University of California San Diego Medical Center, CA (United States). Div. of Radiation Oncology; Schoenfeld, I.; Serig, D.I. [Nuclear Regulatory Commission, Washington, DC (United States). Div. of Systems Technology

    1995-05-01

    A human factors project on the use of nuclear by-product material to treat cancer using remotely operated afterloaders was undertaken by the Nuclear Regulatory Commission. The purpose of the project was to identify factors that contribute to human error in the system for remote afterloading brachytherapy (RAB). This report documents the findings from the first phase of the project, which involved an extensive function and task analysis of RAB. This analysis identified the functions and tasks in RAB, made preliminary estimates of the likelihood of human error in each task, and determined the skills needed to perform each RAB task. The findings of the function and task analysis served as the foundation for the remainder of the project, which evaluated four major aspects of the RAB system linked to human error: human-system interfaces; procedures and practices; training and qualifications of RAB staff; and organizational practices and policies. At its completion, the project identified and prioritized areas for recommended NRC and industry attention based on all of the evaluations and analyses.

  9. Commercial applications of solar total energy systems. Volume 4. Appendices. Final report. [Solar Total Energy System Evaluation Program (STESEP) code

    Energy Technology Data Exchange (ETDEWEB)

    Boobar, M.G.; McFarland, B.L.; Nalbandian, S.J.; Willcox, W.W.; French, E.P.; Smith, K.E.

    1978-07-01

    A methodology has been developed by Atomics International under contract to the Department of Energy to define the applicability of solar total energy systems (STES) to the commercial sector (e.g., retail stores, shopping centers, offices, etc.) in the United States. Candidate STES concepts were selected to provide on-site power generation capability, as well as thermal energy for both heating and cooling applications. Each concept was evaluated on the basis of its cost effectiveness (i.e., as compared to other concepts) and its ability to ultimately penetrate and capture a significant segment of this market, thereby resulting in a saving of fossil fuel resources. This volume contains the appendices. Topics include deterministic insolation model computer code; building energy usage data; computer simulation programs for building energy demand analysis; model buildings for STES evaluation; Solar Total Energy System Evaluation Program (STESEP) computer code; transient simulation of STES concept; solar data tape analysis; program listings and sample output for use with TRNSYS; transient simulation, and financial parameters sensitivities. (WHK)

  10. An intercomparison on radionuclides in environmental samples, Baltic-Danish co-operation project on radiation protection 2001-2003

    DEFF Research Database (Denmark)

    Nielsen, S.P.

    2004-01-01

    , 241Am, 226Ra, 232Th and 40K. The evaluation of analytical performance was based on comparison with median values, a 10% target standard deviation and statistical tests at the 99% level. For 137Cs the resultsfrom 10 out of 16 laboratories passed the evaluation tests. For 90Sr the results from 5 out...... laboratories passed the evaluation tests. The results indicate that for several of the laboratories there isroom to improve the analytical quality on radionuclides in environmental samples to match an uncertainty corresponding to a relative standard deviation of 10%....

  11. The ADVANCE project: Formal evaluation of the targeted deployment. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-01-01

    The ADVANCE familiar driver test provided a small sample of drivers familiar with their local road network and patterns of recurring congestion with an opportunity to drive a vehicle equipped with the ADVANCE dynamic route guidance system for a period of two weeks of normal use. On the basis of this test experience, drivers were asked to evaluate the ADVANCE system and to assess the value of features for future in-vehicle route guidance systems. This test involved 80 volunteer households living in the ADVANCE test area in northwest suburban Chicago; 110 drivers from these households used the ADVANCE vehicle and responded to both baseline (pre-test) and post-test surveys. Thirty two of these drivers participated in focus groups. Drivers also maintained written logs describing their rerouting experiences with the ADVANCE system.

  12. Evaluation of potential geothermal reservoirs in central and western New York State. Volume 3. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1983-06-01

    Computer processed geophysical well logs from central and western New York State were analysed to evaluate the potential of subsurface formations as a source for low-temperature geothermal water. The analysis indicated that porous sandstone sections at the top of the Ordovician Theresa Formation and at the base of the Cambrian Potsdam Formation have the required depth, porosity, and permeability to act as a source for geothermal fluids over a relatively large area in the central part of the state. The fluid potential plus an advantageous geothermal gradient and the results of the test well drilled in the city of Auburn in Cayuga County suggest that low temperature geothermal energy may ba a viable alternative to other more conventional forms of energy that not indigenous to New York State.

  13. Technology evaluation report of Retech, Inc., Plasma Centrifugal Furnace, volume 1

    Science.gov (United States)

    1992-07-01

    A demonstration of the Retech, Inc. Plasma Centrifugal Furnace (PCF) was conducted under the Superfund Innovative Technology Evaluation (SITE) Program at the Department of Energy's (DOE's) Component Development and Integration Facility in Butte, Montana. The furnace uses heat generated from a plasma arc to melt and vitrify solid feed material. The feed soil was a mixture of Silver Bow Creek soil and 10 percent by weight No. 2 diesel oil, spiked to provide 28,000 ppm zinc oxide and 1000 ppm hexichlorobenzene in the soil/oil mixture. Pre-treatment soil and scrubber liquor/makeup sampling was performed to characterize the material inputs to the process. Following treatment, the vitrified soil, scrubber liquor, and stack gas were sampled to determine the technology's suitability for use in destroying and immobilizing contaminants in the test soil. The results from the test were used to draw conclusions on the technology. The conclusions derived from the test results are presented.

  14. Low-rank coal study: national needs for resource development. Volume 3. Technology evaluation

    Energy Technology Data Exchange (ETDEWEB)

    1980-11-01

    Technologies applicable to the development and use of low-rank coals are analyzed in order to identify specific needs for research, development, and demonstration (RD and D). Major sections of the report address the following technologies: extraction; transportation; preparation, handling and storage; conventional combustion and environmental control technology; gasification; liquefaction; and pyrolysis. Each of these sections contains an introduction and summary of the key issues with regard to subbituminous coal and lignite; description of all relevant technology, both existing and under development; a description of related environmental control technology; an evaluation of the effects of low-rank coal properties on the technology; and summaries of current commercial status of the technology and/or current RD and D projects relevant to low-rank coals.

  15. Evaluation of Public Service Electric & Gas Company`s standard offer program, Volume I

    Energy Technology Data Exchange (ETDEWEB)

    Goldman, C.A.; Kito, M.S.; Moezzi, M.M.

    1995-07-01

    In May 1993, Public Service Electric and Gas (PSE&G), the largest investor-owned utility in New Jersey, initiated the Standard Offer program, an innovative approach to acquiring demand-side management (DSM) resources. In this program, PSE&G offers longterm contracts with standard terms and conditions to project sponsors, either customers or third-party energy service companies (ESCOs), on a first-come, first-serve basis to fill a resource block. The design includes posted, time-differentiated prices which are paid for energy savings that will be verified over the contract term (5, 10, or 15 years) based on a statewide measurement and verification (M&V) protocol. The design of the Standard Offer differs significantly from DSM bidding programs in several respects. The eligibility requirements and posted prices allow ESCOs and other energy service providers to market and develop projects among customers with few constraints on acceptable end use efficiency technologies. In contrast, in DSM bidding, ESCOs typically submit bids without final commitments from customers and the utility selects a limited number of winning bidders who often agree to deliver a pre-specified mix of savings from various end uses in targeted markets. The major objectives of the LBNL evaluation were to assess market response and customer satisfaction; analyze program costs and cost-effectiveness; review and evaluate the utility`s administration and delivery of the program; examine the role of PSE&G`s energy services subsidiary (PSCRC) in the program and the effect of its involvement on the development of the energy services industry in New Jersey; and discuss the potential applicability of the Standard Offer concept given current trends in the electricity industry (i.e., increasing competition and the prospect of industry restructuring).

  16. Fuel cycle evaluations of biomass-ethanol and reformulated gasoline. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Tyson, K.S.

    1993-11-01

    The US Department of Energy (DOE) is using the total fuel cycle analysis (TFCA) methodology to evaluate energy choices. The National Energy Strategy (NES) identifies TFCA as a tool to describe and quantify the environmental, social, and economic costs and benefits associated with energy alternatives. A TFCA should quantify inputs and outputs, their impacts on society, and the value of those impacts that occur from each activity involved in producing and using fuels, cradle-to-grave. New fuels and energy technologies can be consistently evaluated and compared using TFCA, providing a sound basis for ranking policy options that expand the fuel choices available to consumers. This study is limited to creating an inventory of inputs and outputs for three transportation fuels: (1) reformulated gasoline (RFG) that meets the standards of the Clean Air Act Amendments of 1990 (CAAA) using methyl tertiary butyl ether (MTBE); (2) gasohol (E10), a mixture of 10% ethanol made from municipal solid waste (MSW) and 90% gasoline; and (3) E95, a mixture of 5% gasoline and 95% ethanol made from energy crops such as grasses and trees. The ethanol referred to in this study is produced from lignocellulosic material-trees, grass, and organic wastes -- called biomass. The biomass is converted to ethanol using an experimental technology described in more detail later. Corn-ethanol is not discussed in this report. This study is limited to estimating an inventory of inputs and outputs for each fuel cycle, similar to a mass balance study, for several reasons: (1) to manage the size of the project; (2) to provide the data required for others to conduct site-specific impact analysis on a case-by-case basis; (3) to reduce data requirements associated with projecting future environmental baselines and other variables that require an internally consistent scenario.

  17. Mean nuclear volume

    DEFF Research Database (Denmark)

    Mogensen, O.; Sørensen, Flemming Brandt; Bichel, P.

    1999-01-01

    We evaluated the following nine parameters with respect to their prognostic value in females with endometrial cancer: four stereologic parameters [mean nuclear volume (MNV), nuclear volume fraction, nuclear index and mitotic index], the immunohistochemical expression of cancer antigen (CA125...

  18. Co-operation Agreement between the European Organization for Nuclear Research (CERN) and King Abdulaziz City for Science and Technology (KACST) on behalf of the Government of the Kingdom of Saudi Arab

    CERN Document Server

    2005-01-01

    Co-operation Agreement between the European Organization for Nuclear Research (CERN) and King Abdulaziz City for Science and Technology (KACST) on behalf of the Government of the Kingdom of Saudi Arab

  19. Cooperation Agreement between the European Organization for Nuclear Research (CERN) and The Qatar Foundation for Education, Science and Community Development concerning Scientific and Technical Co-operation in High Energy Physics

    CERN Document Server

    2016-01-01

    Cooperation Agreement between the European Organization for Nuclear Research (CERN) and The Qatar Foundation for Education, Science and Community Development concerning Scientific and Technical Co-operation in High Energy Physics

  20. Supplementary agreement prolonging the agreement constituting a council of representatives of European states for d planning an international laboratory and organizing other forms of co-operation in nuclear research; Paris, 30th June 1953

    CERN Document Server

    CERN. Geneva

    1953-01-01

    Supplementary agreement prolonging the agreement constituting a council of representatives of European states for d planning an international laboratory and organizing other forms of co-operation in nuclear research; Paris, 30th June 1953

  1. Economic evaluation of the Annual Cycle Energy System (ACES). Volume II. Detailed results. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1980-05-01

    The energy effectiveness and the economic viability of the ACES concept are examined. ACES is studied in a variety of different applications and compared to a number of conventional systems. The different applications are studied in two groups: the class of building into which the ACES is incorporated and the climatic region in which the ACES is located. Buildings investigated include single-family and multi-family residences and a commercial office building. The application of ACES to each of these building types is studied in Minneapolis, Atlanta, and Philadelphia. The economic evaluation of the ACES is based on a comparison of the present worth of the ACES to the present worth of conventional systems; namely, electric resistance heating, electric air conditioning, and electric domestic water heating; air-to-air heat pump and electric domestic water heating; oil-fired furnace, electric air conditioning, and electric domestic water heating; and gas-fired furnace, electric air conditioning, and gas domestic water heating.

  2. Radiological characterization and evaluation of high volume bauxite residue alkali activated concretes.

    Science.gov (United States)

    Croymans, Tom; Schroeyers, Wouter; Krivenko, Pavel; Kovalchuk, Oleksandr; Pasko, Anton; Hult, Mikael; Marissens, Gerd; Lutter, Guillaume; Schreurs, Sonja

    2017-03-01

    Bauxite residue, also known as red mud, can be used as an aggregate in concrete products. The study involves the radiological characterization of different types of concretes containing bauxite residue from Ukraine. The activity concentrations of radionuclides from the 238 U, 232 Th decay series and 40 K were determined for concrete mixture samples incorporating 30, 40, 50, 60, 75, 85 and 90% (by mass) of bauxite residue using gamma-ray spectrometry with a HPGe detector. The studied bauxite residue can, from a radiological point of view using activity concentration indexes developed by Markkanen, be used in concrete for building materials and in road construction, even in percentages reaching 90% (by mass). However, when also occupational exposure is considered it is recommended to incorporate less than 75% (by mass) of Ukrainian bauxite residue during the construction of buildings in order to keep the dose to workers below the dose criterion used by Radiation Protection (RP) 122 (0.3 mSv/a). Considering RP122 for evaluation of the total effective dose to workers no restrictions are required for the use of the Ukrainian bauxite residue in road construction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Evaluation of spacecraft technology programs (effects on communication satellite business ventures), volume 1

    Science.gov (United States)

    Greenburg, J. S.; Gaelick, C.; Kaplan, M.; Fishman, J.; Hopkins, C.

    1985-01-01

    Commercial organizations as well as government agencies invest in spacecraft (S/C) technology programs that are aimed at increasing the performance of communications satellites. The value of these programs must be measured in terms of their impacts on the financial performane of the business ventures that may ultimately utilize the communications satellites. An economic evaluation and planning capability was developed and used to assess the impact of NASA on-orbit propulsion and space power programs on typical fixed satellite service (FSS) and direct broadcast service (DBS) communications satellite business ventures. Typical FSS and DBS spin and three-axis stabilized spacecraft were configured in the absence of NASA technology programs. These spacecraft were reconfigured taking into account the anticipated results of NASA specified on-orbit propulsion and space power programs. In general, the NASA technology programs resulted in spacecraft with increased capability. The developed methodology for assessing the value of spacecraft technology programs in terms of their impact on the financial performance of communication satellite business ventures is described. Results of the assessment of NASA specified on-orbit propulsion and space power technology programs are presented for typical FSS and DBS business ventures.

  4. Fresh Kills leachate treatment and minimization study: Volume 2, Modeling, monitoring and evaluation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Fillos, J.; Khanbilvardi, R.

    1993-09-01

    The New York City Department of Sanitation is developing a comprehensive landfill leachate management plan for the Fresh Kills landfill, located on the western shore of Staten Island, New York. The 3000-acre facility, owned and operated by the City of New York, has been developed into four distinct mounds that correspond to areas designated as Sections 1/9, 2/8, 3/4 and 6/7. In developing a comprehensive leachate management plan, the estimating leachate flow rates is important in designing appropriate treatment alternatives to reduce the offsite migration that pollutes both surface water and groundwater resources.Estimating the leachate flow rates from Sections 1/9 and 6/7 was given priority using an available model, hydrologic evaluation of landfill performance (HELP), and a new model, flow investigation for landfill leachate (FILL). The field-scale analysis for leachate flow included data collection of the leachate mound-level from piezometers and monitoring wells installed on-site, for six months period. From the leachate mound-head contours and flow-gradients, Leachate flow rates were computed using Darcy`s Law.

  5. Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA

    Science.gov (United States)

    Callow, Philip; Rajasekar, Karthik V.; Timmins, Peter; Patel, Trushar R.; Siligardi, Giuliano; Hussain, Rohanah; White, Scott A.; Thomas, Christopher M.

    2017-01-01

    The ParB protein, KorB, from the RK2 plasmid is required for DNA partitioning and transcriptional repression. It acts co-operatively with other proteins, including the repressor KorA. Like many multifunctional proteins, KorB contains regions of intrinsically disordered structure, existing in a large ensemble of interconverting conformations. Using NMR spectroscopy, circular dichroism and small-angle neutron scattering, we studied KorB selectively within its binary complexes with KorA and DNA, and within the ternary KorA/KorB/DNA complex. The bound KorB protein remains disordered with a mobile C-terminal domain and no changes in the secondary structure, but increases in the radius of gyration on complex formation. Comparison of wild-type KorB with an N-terminal deletion mutant allows a model of the ensemble average distances between the domains when bound to DNA. We propose that the positive co-operativity between KorB, KorA and DNA results from conformational restriction of KorB on binding each partner, while maintaining disorder. PMID:28760886

  6. Japan-Australia co-operative program on research and development of technology for the management of high level radioactive wastes. Final report 1985 to 1998

    Energy Technology Data Exchange (ETDEWEB)

    Hart, K.; Vance, E.; Lumpkin, G. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia); Mitamura, H.; Banba, T. [Japan Atomic Energy Research Inst. Tokai, Ibaraki (Japan)

    1998-12-01

    The overall aim of the Co-operative Program has been to promote the exchange of information on technology for the management of High-Level Wastes (HLW) and to encourage research and development relevant to such technology. During the 13 years that the Program has been carried out, HLW management strategies have matured and developed internationally, and Japan has commenced construction of a domestic reprocessing and vitrification facility for HLW. The HLW management strategy preferred is a national decision. Many countries are using vitrification, direct disposal of spent fuel or a combination of both to handle their existing wastes whereas others have deferred the decision. The work carried out in the Co-operative Program provides strong scientific evidence that the durability of ceramic waste forms is not significantly affected by radiation damage and that high loadings of actinide elements can be incorporated into specially designed ceramic waste forms. Moreover, natural minerals have been shown to remain as closed systems for U and Th for up to 2.5 b y. All of these results give confidence in the ability of second generation waste forms, such as Synroc, to handle future waste arisings that may not be suitable for vitrification 87 refs., 15 tabs., 22 figs.

  7. Planning of biogas plants. A question of co-operation and negotiation; Planering av biogasanlaeggningar. En fraaga om samverkan och foerhandling

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Jamil

    2003-04-01

    During the last years there has been an increased interest in Sweden to build biogas reactors. The planning of a biogas plant brings about the need for co-operation between a variety of actors. Furthermore, there are a number of different issues that need to be dealt with. To build a biogas plant is thus a rather complicated thing to do. The aim of this report is to increase the knowledge about the processes that precede a decision to build a biogas plant, in order to try to facilitate the planning of future projects. The report is based on case studies of the planning of two biogas plants in Sweden and the empirical material consists of interviews with key persons as well as written documents. In the study, three parallel processes are identified and analysed, which are all crucial to carry through a project. These are the project planning process, the political process and the application process. The most important result of the study is that there is not only one way to carry through a project and that the choice of strategy depends on the character of the project and the different questions that need to be handled. Examples of other results are: the importance of an early and continuous dialogue with the political leadership, the necessity to build an organisation for the co-operation between key actors and that the project leaders should be flexible and open to changes in the project throughout the planning process.

  8. Intrinsic disorder in the partitioning protein KorB persists after co-operative complex formation with operator DNA and KorA.

    Science.gov (United States)

    Hyde, Eva I; Callow, Philip; Rajasekar, Karthik V; Timmins, Peter; Patel, Trushar R; Siligardi, Giuliano; Hussain, Rohanah; White, Scott A; Thomas, Christopher M; Scott, David J

    2017-08-30

    The ParB protein, KorB, from the RK2 plasmid is required for DNA partitioning and transcriptional repression. It acts co-operatively with other proteins, including the repressor KorA. Like many multifunctional proteins, KorB contains regions of intrinsically disordered structure, existing in a large ensemble of interconverting conformations. Using NMR spectroscopy, circular dichroism and small-angle neutron scattering, we studied KorB selectively within its binary complexes with KorA and DNA, and within the ternary KorA/KorB/DNA complex. The bound KorB protein remains disordered with a mobile C-terminal domain and no changes in the secondary structure, but increases in the radius of gyration on complex formation. Comparison of wild-type KorB with an N-terminal deletion mutant allows a model of the ensemble average distances between the domains when bound to DNA. We propose that the positive co-operativity between KorB, KorA and DNA results from conformational restriction of KorB on binding each partner, while maintaining disorder. © 2017 The Author(s).

  9. An evaluation of the feasibility of assessment of volume perfusion for the whole lung by 128-slice spiral CT

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Haitao [Imaging Center of Taian Central Hospital, Taian, Shandong (China); Gao, Fei; Li, Ning; Liu, Cheng [Shandong Univ., Shandong Medical Imaging Research Inst., CT Room, Shandong (China)], e-mail: liucheng491025@sina.com

    2013-10-15

    Background: Lung perfusion based on dynamic scanning cannot provide a quantitative assessment of the whole lung because of the limited coverage of the current computed tomography (CT) detector designs. Purpose: To evaluate the feasibility of dynamic volume perfusion CT (VPCT) of the whole lung using a 128-slice CT for the quantitative assessment and visualization of pulmonary perfusion. Material and Methods: Imaging was performed in a control group of 17 subjects who had no signs of disturbance of pulmonary function or diffuse lung disease, and 15 patients (five patients with acute pulmonary embolism and 10 with emphysema) who constituted the abnormal lung group. Dynamic VPCT was performed in all subjects, and pulmonary blood flow (PBF), pulmonary blood volume (PBV), and mean transit time (MTT) were calculated from dynamic contrast images with a coverage of 20.7 cm. Regional and volumetric PBF, PBV, and MTT were statistically evaluated and comparisons were made between the normal and abnormal lung groups. Results: Regional PBF (94.2{+-}36.5, 161.8 {+-}29.6, 185.7 {+-}38.1 and 125.5 {+-}46.1, 161.9 {+-}31.4, 169.3 {+-}51.7), PBV (6.7 {+-}2.8, 10.9 {+-}3.0, 12.9 {+-}4.5 and 9.9 {+-}4.6, 10.3 {+-}2.9, 11.9 {+-}4.5), and MTT (5.8 {+-}2.4, 4.5 {+-}1.3, 4.7 {+-}2.1 and 5.6 {+-}2.3, 4.3 {+-}1.5, 4.9 {+-}1.5) demonstrated significant differences in the gravitational and isogravitational directions in the normal lung group (P < 0.05). The PBF (154.2 {+-}30.6 vs. 94.9 {+-}15.9) and PBV (11.1 {+-}4.0 vs. 6.6 {+-}1.7) by dynamic VPCT showed significant differences between normal and abnormal lungs (P < 0.05), notwithstanding the four large lungs that had coverage > 20.7 cm. Conclusion: Dynamic VPCT of the whole lung is feasible for the quantitative assessment of pulmonary perfusion by 128-slice CT, and may in future permit the evaluation of both morphological and functional features of the whole lung in a single examination.

  10. Metabolic evaluation and measurement of ovarian volume in polycystic ovary sydrome: a cross-sectional observational study

    Directory of Open Access Journals (Sweden)

    Mehtap Evran

    2016-03-01

    Full Text Available Purpose: Polycystic ovary sydrome is a disease of women in reproductive period, with hirsutism or hyperandrogenic signs in laboratory evaluation, causing infertility due to dysmenorrhea and unovulation. Accompanying insulin resistance and adiposity may increase cardiometabolic risk. In our study, we planned to represent the physical examination and laboratory findings of the patients diagnosed as polycystic ovary sydrome, together with andominal ultrasonographic evaluation of the ovaries. Material-methods: Twenty-two patients who admitted the endocrinology department with the complaints of hirsutism and dysmenorrhea were included in the study. Purpose: Polycystic ovary sydrome is a disease of women in reproductive period, with hirsutism or hyperandrogenic signs in laboratory evaluation, causing infertility due to dysmenorrhea and unovulation. Accompanying insulin resistance and adiposity may increase cardiometabolic risk. In our study, we planned to represent the physical examination and laboratory findings of the patients diagnosed as polycystic ovary sydrome, together with andominal ultrasonographic evaluation of the ovaries. Material and Methods: Twenty-two patients who admitted the endocrinology department with the complaints of hirsutism and dysmenorrhea were included in the study. Their ages, family histories, polycystic ovary sydrome phenotypes, first menstrual age, length of cyclus and physical examination findings were recorded. Ferriman and Gallwey score was used for hirsutism. Insulin resistance was calculated via HOMA-IR method by making the biochemical and hormonal tests. Ovarian volumes were measured by abdominal ultrasonography. SPSS-16 was used for the statistical analysis of the findings. Results: Mean age was 21.41+/-0.88. Polycystic ovary sydrome phenotypes were B in 40.9%, C in 31.8% and A in 27.3%. Cyclus length was normal in 31.8% (27-34 days. Ferriman and Gallwey score was and #8805;7 in all of the patients. Although

  11. Office for Analysis and Evaluation of Operational Data 1992 annual report: Power reactors. Volume 7, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    None

    1993-07-01

    The annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) is devoted to the activities performed during 1992. The report is published in two separate parts. NUREG-1272, Vol. 7, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about the trends of some key performance, measures. The report also includes the principal findings and issues identified in AEOD studies over the past year, and summarizes information from such sources as licensee event report% diagnostic evaluations, and reports to the NRC`s Operations Center. The reports contain a discussion of the Incident Investigation Team program and summarize the Incident Investigation Team and Augmented Inspection Team reports for that group of licensees. NUREG-1272, Vol. 7, No. 2, covers nonreactors and presents a review of the events and concerns during 1992 associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Each volume contains a list of the AEOD reports issued for 1984--1992.

  12. Office for Analysis and Evaluation of Operational Data 1994-FY 95 annual report. Volume 9, Number 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) describes activities conducted during CY 1994 and FY 1995. The report is published in three parts. NUREG-1272, Vol. 9, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about the trends of some key performance measures. The report also includes the principal findings and issues identified in AEOD studies over the past year and summarizes information from such sources as licensee event reports, diagnostic evaluations, and reports to the NRC`s Operations Center. NUREG-1272, Vol. 9, No. 2, covers nuclear materials and presents a review of the events and concerns associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Both reports also contain a discussion of the Incident Investigation Team program and summarize both the Incident Investigation Team and Augmented Inspection Team reports. Each volume contains a list of the AEOD reports issued from 1980 through FY 1995. NUREG-1272, Vol. 9, No. 3, covers technical training and presents the activities of the Technical Training Center in support of the NRC`s mission.

  13. The Patchwork Text and Business Education: Rethinking the Importance of Personal Reflection and Co-operative Cultures.

    Science.gov (United States)

    Illes, Katalin

    2003-01-01

    Describes and evaluates the introduction of the Patchwork Text assignment in the assessment of a Masters-level course on Intercultural Management taught to students of various nationalities and linguistic/cultural backgrounds as part of a Masters-level business education program. Begins by addressing the question of whether the Patchwork Text…

  14. Quantitative evaluation of masseter muscle volume in different growth patterns and its correlation with facial morphology: Cone beam computed tomography study

    Directory of Open Access Journals (Sweden)

    Mukesh Gupta

    2016-01-01

    Full Text Available Objective: This investigation was designed to evaluate the masseter muscle volume in different growth patterns and its correlation with facial morphology using three-dimensional cone beam computed tomography (CBCT, Materials and Methods: Study was conducted using CBCT scans of nonorthodontically treated individuals (n = 32, 19 males and 13 females between the ages of 18–25 years. The masseter muscle volume was calculated using Dolphin 3D software 11.5 version (Essential Dental Products, New Delhi, India. The subjects were grouped according to growth pattern and facial form. Conclusion: CBCT predicts actual muscle volume by calculating number of voxels of scan data and exact geometry of the muscle. The mean masseter muscle volume was 28.73 ± 5.51 cm3 for horizontal growth patterns, 27.30 ± 6.49 cm3 for average growth pattern, and 22.14 ± 3.25 cm3 for vertical growth pattern. The individuals with thin masseter morphology had a longer face in proportion/relation to their facial width with an increase in masseter muscle volume, the facial index decreased, and face appeared to be more rectangular. Euryprosopic facial form showed maximum/highest masseter muscle volume, whereas leptoprosopic facial form showed least muscle volume.

  15. FY 1998 Report on development of technologies for commercialization of photovoltaic power systems. International co-operative project (IEA implementing agreement for a co-operative programme on photovoltaic power systems); 1998 nendo taiyoko hatsuden system jitsuyoka gijutsu kaihatsu kokusai kyoryoku jigyo. IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Described herein are outline of the International Energy Agency/Co-operative programme on Photovoltaic Power Systems (IEA/PVPS). Japan signed the IEA Implementing Agreement for a co-operative programme on Photovoltaic Power Systems in April 1993, and has been participating in the programme for research and development, demonstration, analysis, information exchange and introduction promotion, among others. This programme is managed by Executive Committee composed of the representatives, one nominated by each participating country, and each task is managed by each Operating Agency. There are 9 tasks (Tasks 1 to 9), and Executive Committee deliberates and approves the plans, and manages the progresses, budgetary plans and budgets for each task. IEA implementing agreement for a co-operative programme on PVPS, originally set effective for 5 years, has been extended for another 5 years to 2002, and the second phase activities have been started. The 9th to 11th Executive Committee meetings were held during the 1997-1998 period in Denmark, ROK, Spain, Austria and Australia, respectively. (NEDO)

  16. 1980 survey and evaluation of utility conservation, load management, and solar end-use projects. Volume 3: utility load management projects. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1982-01-01

    The results of the 1980 survey of electric utility-sponsored energy conservation, load management, and end-use solar energy conversion projects are described. The work is an expansion of a previous survey and evaluation and has been jointly sponsored by EPRI and DOE through the Oak Ridge National Laboratory. There are three volumes and a summary document. Each volume presents the results of an extensive survey to determine electric utility involvement in customer-side projects related to the particular technology (i.e., conservation, solar, or load management), selected descriptions of utility projects and results, and first-level technical and economic evaluations.

  17. 9 May 2008 - Signature of the Protocol to the co-operation agreement dated 21 January 2006 between King Abdulaziz City for Science and Technology (KACST) on behalf of the Government of the Kingdom of Saudi Arabia, represented by M. I. Al-Suwaiyel and the European Organization for Nuclear Research (CERN), represented by R. Aymar, concerning the further development of scientific and technical co-operation in high-energy physics

    CERN Multimedia

    Maximilien Brice

    2008-01-01

    9 May 2008 - Signature of the Protocol to the co-operation agreement dated 21 January 2006 between King Abdulaziz City for Science and Technology (KACST) on behalf of the Government of the Kingdom of Saudi Arabia, represented by M. I. Al-Suwaiyel and the European Organization for Nuclear Research (CERN), represented by R. Aymar, concerning the further development of scientific and technical co-operation in high-energy physics

  18. Oak Ridge K-25 Site Technology Logic Diagram. Volume 3, Technology evaluation data sheets; Part A, Characterization, decontamination, dismantlement

    Energy Technology Data Exchange (ETDEWEB)

    Fellows, R.L. [ed.

    1993-02-26

    The Oak Ridge K-25 Technology Logic Diagram (TLD), a decision support tool for the K-25 Site, was developed to provide a planning document that relates environmental restoration and waste management problems at the Oak Ridge K-25 Site to potential technologies that can remediate these problems. The TLD technique identifies the research necessary to develop these technologies to a state that allows for technology transfer and application to waste management, remedial action, and decontamination and decommissioning activities. The TLD consists of four separate volumes-Vol. 1, Vol. 2, Vol. 3A, and Vol. 3B. Volume 1 provides introductory and overview information about the TLD. Volume 2 contains logic diagrams. Volume 3 has been divided into two separate volumes to facilitate handling and use. This report is part A of Volume 3 concerning characterization, decontamination, and dismantlement.

  19. Office for Analysis and Evaluation of Operational Data 1996 annual report. Volume 10, Number 3: Technical training

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    This annual report of the US Nuclear Regulatory Commission`s Office for Analysis and Evaluation of Operational Data (AEOD) describes activities conducted during 1996. The report is published in three parts. NUREG-1272, Vol. 10, No. 1, covers power reactors and presents an overview of the operating experience of the nuclear power industry from the NRC perspective, including comments about trends of some key performance measures. The report also includes the principal findings and issues identified in AEOD studies over the past year and summarizes information from such sources as licensee event reports and reports to the NRC`s Operations Center. NUREG-1272, Vol. 10, No. 2, covers nuclear materials and presents a review of the events and concerns during 1996 associated with the use of licensed material in nonreactor applications, such as personnel overexposures and medical misadministrations. Both reports also contain a discussion of the Incident Investigation Team program and summarize both the Incident Investigation Team and Augmented Inspection Team reports. Each volume contains a list of the AEOD reports issued from CY 1980 through 1996. NUREG-1272, Vol. 10, No. 3, covers technical training and presents the activities of the Technical Training Center in support of the NRC`s mission in 1996.

  20. Field Evaluation of Indoor Thermal Fog and Ultra-Low Volume Applications For Control of Aedes aegypti in Thailand.

    Science.gov (United States)

    Ponlawat, A; Harwood, J F; Putnam, J L; Nitatsukprasert, C; Pongsiri, A; Kijchalao, U; Linthicum, K J; Kline, D L; Clark, G G; Obenauer, P J; Doud, C W; Mccardle, P W; Richardson, A G; Szumlas, D E; Richardson, J H

    2017-06-01

    Efficacies of a handheld thermal fogger (Patriot™) and a backpack ultra-low volume (ULV) sprayer (Twister™) with combinations of 2 different adulticides (pyrethrin, deltamethrin) and an insect growth regulator (pyriproxyfen) were field-tested and compared for their impact on reducing indoor Aedes aegypti populations in Thailand. The effectiveness of the indoor space sprays was evaluated by sampling the natural Ae. aegypti population in houses and determining their physiological status, by monitoring mortality of sentinel caged mosquitoes (AFRIMS strain) and by assessing larval mortality in laboratory bioassays using water exposed to the spray. A total of 14,742 Ae. aegypti were collected from Biogents Sentinel traps in this study. The combination of ULD® BP-300 (3% pyrethrin) and NyGuard® (10% pyriproxyfen) sprayed either by the Patriot or Twister significantly reduced some Ae. aegypti populations up to 20 days postspray relative to the control clusters. The addition of pyriproxyfen to the adulticide extended how long household mosquito populations were suppressed. In 2 of the 4 products being compared, the Twister resulted in higher mortality of caged mosquitoes compared with the Patriot. However, neither machine was able to achieve high mortality among Ae. aegypti placed in hidden (protected) cages. The larval bioassay results demonstrated that the Twister ULV provided better adult emergence inhibition than the Patriot (thermal fogger), likely due to larger droplet size.

  1. Performance Evaluation of Advanced Retrofit Roof Technologies Using Field-Test Data Phase Three Final Report, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Biswas, Kaushik [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Childs, Phillip W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Atchley, Jerald Allen [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-01-01

    This article presents some miscellaneous data from two low-slope and two steep-slope experimental roofs. The low-slope roofs were designed to compare the performance of various roof coatings exposed to natural weatherization. The steep-slope roofs contained different combinations of phase change material, rigid insulation, low emittance surface and above-sheathing ventilation, with standing-seam metal panels on top. The steep-slope roofs were constructed on a series of adjacent attics separated at the gables using thick foam insulation. This article describes phase three (3) of a study that began in 2009 to evaluate the energy benefits of a sustainable re-roofing technology utilizing standing-seam metal roofing panels combined with energy efficient features like above-sheathing-ventilation (ASV), phase change material (PCM) and rigid insulation board. The data from phases 1 and 2 have been previously published and reported [Kosny et al., 2011; Biswas et al., 2011; Biswas and Childs, 2012; Kosny et al., 2012]. Based on previous data analyses and discussions within the research group, additional test roofs were installed in May 2012, to test new configurations and further investigate different components of the dynamic insulation systems. Some experimental data from phase 3 testing from May 2012 to December 2013 and some EnergyPlus modeling results have been reported in volumes 1 and 3, respectively, of the final report [Biswas et al., 2014; Biswas and Bhandari, 2014].

  2. Task 9: deployment of photovoltaic technologies: co-operation with developing countries. Sources of financing for PV-based rural electrification in developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Parker, W. [Institute for Sustainable Power, Highlands Ranch, CO (United States); Syngellakis, K. [IT Power Ltd, The Manor house, Chineham (United Kingdom); Shanker, A. [Innovation Energie Developpement, IED, Francheville (France)

    2004-05-15

    This report for the International Energy Agency (IEA) made by Task 9 of the Photovoltaic Power Systems (PVPS) programme takes a look at how PV-based rural electrification in developing countries can be financed. The objective of Task 9 is to increase the overall rate of successful deployment of PV systems in developing countries through increased co-operation and information exchange. This document provides an introduction to PV project financing, including funding sources available, strategies and planning needed to secure the necessary financial resources for the deployment of PV technologies in developing and transitional economies. Topics discussed include risk analysis and the barriers to financing, sources of financing, considerations and variables that influence financing decisions and the process for securing financing. Various forms of international and national financing are looked at, as are the factors influencing financing decisions.

  3. Love at first sight. Co-operation between the Netherlands and Norway on the peaceful use of atomic energy, 1950-1960

    Energy Technology Data Exchange (ETDEWEB)

    Splunter, J.M. van

    1994-12-31

    This study describes the co-operation during the fifties and sixties between the Netherlands and Norway in the sphere of the peaceful use of nuclear energy. It is the story about the establishment, development and abolishment of the Joint Establishment for Nuclear Energy Research (JENER) at Kjeller, Norway. The start of operation of the Norwegian-Dutch reactor JEEP at Kjeller in July 1951 heralded the first phase of JENER. This rector became the first reactor in the world to be built outside the big-power states. The present study explains how it was possible for to two small states to go ahead with a reactor project at the outset of the post-war period. 13 refs.

  4. From the sage on the stage to what exactly? Description and the place of the moderator in co-operative and collaborative learning

    Directory of Open Access Journals (Sweden)

    Chris Jones

    1999-12-01

    Full Text Available In a standard text on open and distance learning, computer conferencing appears with advantages and disadvantages that rely on the capacity of the conference to 'facilitate' students and staff working together (Mason, 1994. Co-operation or collaboration are seen as unproblematic outcomes of the use of the computer conference. Hiltz noted that collaboration is both technically facilitated and becomes a moral requirement that involves a respecification of the teacher's role (Hiltz and Benbunan-Fich, 1997, p. 1. The outlook that associates collaborative learning with computer conferencing can be found throughout a wide range of literature (Mason and Kaye, 1989; Harasim, 1990; Kaye, 1992; McConnell, 1994; Harasim et al., 1995; O'Malley, 1995; Jonassen, 1996.

  5. FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress

    DEFF Research Database (Denmark)

    Fugger, Kasper; Chu, Wai Kit; Haahr, Peter

    2013-01-01

    The molecular events occurring following the disruption of DNA replication forks are poorly characterized, despite extensive use of replication inhibitors such as hydroxyurea in the treatment of malignancies. Here, we identify a key role for the FBH1 helicase in mediating DNA double-strand break...... formation following replication inhibition. We show that FBH1-deficient cells are resistant to killing by hydroxyurea, and exhibit impaired activation of the pro-apoptotic factor p53, consistent with decreased DNA double-strand break formation. Similar findings were obtained in murine ES cells carrying...... disrupted alleles of Fbh1. We also show that FBH1 through its helicase activity co-operates with the MUS81 nuclease in promoting the endonucleolytic DNA cleavage following prolonged replication stress. Accordingly, MUS81 and EME1-depleted cells show increased resistance to the cytotoxic effects...

  6. TECHNOLOGY EVALUATION REPORT, SITE PROGRAM DEMONSTRATION TEST: SHIRCO PILOT-SCALE INFRARED INCINERATION SYSTEM ROSE TOWNSHIP DEMODE ROAD SUPERFUND SITE - VOLUME II

    Science.gov (United States)

    The performance of the Shirco pilot-scale infrared thermal destruction system has been evaluated at the Rose Township, Demode Road Superfund Site and is presented in the report. The waste tested consisted of solvents, organics and heavy metals in an illegal dump site. Volume I gi...

  7. Feasibility of tissue similarity map-based relative cerebral blood volume assessment in the evaluation of gliomas.

    Science.gov (United States)

    Hu, Chun-Hong; Hu, Su; Gao, Xi; Sun, Chun-Ming; Gan, Wen-Juan; Liu, Yun-Lian; Wen, Fang; Dai, Qi-Chun; Li, Ping

    2015-01-01

    To investigate the feasibility of tissue similarity map (TSM)-based relative cerebral blood volume (rCBV) assessment in evaluating the hemodynamic characteristics of gliomas and in differentiating high-grade gliomas from low-grade ones without concentration time curve (CTC). TSM-based rCBV (rCBV TSM ) and conventional rCBV (rCBV PWI ) maps were generated (n = 35). The differences in percentage and concordance correlation coefficient (CCC) of the rCBV TSM and rCBV PWI ratios were calculated. The Mann-Whitney test and the receiver operating characteristic (ROC) curve analysis were also performed to examine the relationships of rCBV ratios between high- and low-grade gliomas. The improvement factors of signal to noise ratio (SNR) of rCBV TSM maps were also calculated. The mean difference in percentage between rCBV TSM and rCBV PWI ratios was 4.29 ± 2.62%. The CCC of rCBV TSM and rCBV PWI ratios was 0.9974, with 95% confidence interval of 0.9948, 0.9987, which implied a high agreement between them. The Mann-Whitney test suggested that the rCBV TSM and rCBV PWI ratios of high-grade gliomas were significantly different from those of low-grade gliomas (P TSM map were 1.31 ± 0.24 for glioma and 1.28 ± 0.24 for normal white matter. It is feasible to use rCBV TSM in the evaluation of hemodynamic characteristics of gliomas and differentiation of high- and low-grade gliomas without CTC. Moreover, rCBV TSM maps possess a higher SNR, which allows potentially more accurate diagnosis compared with the conventional ones.

  8. The Pilot Study of Evaluating Fluctuation in the Blood Flow Volume of the Radial Artery, a Site for Traditional Pulse Diagnosis

    Directory of Open Access Journals (Sweden)

    Masashi Watanabe

    2016-05-01

    Full Text Available Background: Radial artery (RA pulse diagnosis has been used in traditional Asian medicine. Blood pressure (BP and pulse rate related to heart rate variability (HRV can be monitored via the RA. The fluctuation in these parameters has been assessed using fast Fourier transform (FFT analytical methods that calculate power spectra. Methods: We measured blood flow volume (Volume in the RA and evaluated its fluctuations. Normal participants (n = 34 were enrolled. We measured the hemodynamics of the right RA for approximately 50 s using ultrasonography. Results: The parameters showed the center frequency (CF of the power spectrum at low frequency (LF and high frequency (HF. More than one spectral component indicated that there were fluctuations. The CF at LF for Volume was significantly different from that for vessel diameter (VD; however, it was significantly correlated with blood flow velocity (Velocity. On the other hand, the CF at HF for Volume was significantly different from that for Velocity; however, it was significantly correlated with VD. Conclusion: It is suggested that fluctuation in the Volume at LF of RA is influenced by the fluctuation in Velocity; on the other hand, fluctuation in the Volume at HF is influenced by the fluctuation in VD.

  9. Information transfer to out-of-hours co-operatives: a survey of general practitioners' views in relation to palliative patients.

    Science.gov (United States)

    Kiely, Fiona; Murphy, Marie; O'Brien, Tony

    2013-12-01

    In Ireland, weekend and night medical cover for community based patients is largely provided by general practice co-operatives. Doctors working in this service do not have direct access to patients' medical records which challenges continuity of care. This study investigates the opinion of general practitioners (GPs) on the potential value of a formalised method of information transfer regarding their palliative patients to out-of-hours GP co-operatives. The survey was designed to identify the information that is necessary to offer appropriate anticipated end-of-life care. A questionnaire was sent to all 414 GPs registered in the Irish Medical Directory in the southwest of Ireland. Data were analysed with Microsoft Excel and SPSS V.12.0. 52% response rate with exclusion of incomplete questionnaires allowed analysis of 212 data sets. Currently, 82% of GPs do not routinely transfer information pertaining to end-of-life issues to the out-of-hours service. Despite this, 96% would value a standardised way of transferring information. 67% felt they sometimes refer unnecessarily to hospital emergency departments due to lack of information. The most important items of information identified by study participants are as follows: ▸ Diagnosis (97%) ▸ Medications (94%) ▸ Patient insight (91%) ▸ Patient wishes regarding end-of-life care (90%) ▸ Anticipated problems and suggested management(90%). A structured format for information transfer regarding end-of-life care is deemed important by GPs when working on-call at night and weekends. Diagnosis, patient preference and management plans are valued.

  10. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Functional modules F9--F16 -- Volume 2, Part 2, Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    West, J.T.; Hoffman, T.J.; Emmett, M.B.; Childs, K.W.; Petrie, L.M.; Landers, N.F.; Bryan, C.B.; Giles, G.E. [Oak Ridge National Lab., TN (United States)

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. The manual is divided into three volumes: Volume 1--for the control module documentation, Volume 2--for functional module documentation; and Volume 3--for documentation of the data libraries and subroutine libraries. This volume discusses the following functional modules: MORSE-SGC; HEATING 7.2; KENO V.a; JUNEBUG-II; HEATPLOT-S; REGPLOT 6; PLORIGEN; and OCULAR.

  11. Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: a 'Big Brother' evaluation.

    Science.gov (United States)

    Steenbakkers, Roel J H M; Duppen, Joop C; Fitton, Isabelle; Deurloo, Kirsten E I; Zijp, Lambert; Uitterhoeve, Apollonia L J; Rodrigus, Patrick T R; Kramer, Gijsbert W P; Bussink, Johan; De Jaeger, Katrien; Belderbos, José S A; Hart, Augustinus A M; Nowak, Peter J C M; van Herk, Marcel; Rasch, Coen R N

    2005-11-01

    To evaluate the process of target volume delineation in lung cancer for optimization of imaging, delineation protocol and delineation software. Eleven radiation oncologists (observers) from five different institutions delineated the Gross Tumor Volume (GTV) including positive lymph nodes of 22 lung cancer patients (stages I-IIIB) on CT only. All radiation oncologist-computer interactions were recorded with a tool called 'Big Brother'. For each radiation oncologist and patient the following issues were analyzed: delineation time, number of delineated points and corrections, zoom levels, level and window (L/W) settings, CT slice changes, use of side windows (coronal and sagittal) and software button use. The mean delineation time per GTV was 16 min (SD 10 min). The mean delineation time for lymph node positive patients was on average 3 min larger (P = 0.02) than for lymph node negative patients. Many corrections (55%) were due to L/W change (e.g. delineating in mediastinum L/W and then correcting in lung L/W). For the lymph node region, a relatively large number of corrections was found (3.7 corr/cm2), indicating that it was difficult to delineate lymph nodes. For the tumor-atelectasis region, a relative small number of corrections was found (1.0 corr/cm2), indicating that including or excluding atelectasis into the GTV was a clinical decision. Inappropriate use of L/W settings was frequently found (e.g. 46% of all delineated points in the tumor-lung region were delineated in mediastinum L/W settings). Despite a large observer variation in cranial and caudal direction of 0.72 cm (1 SD), the coronal and sagittal side windows were not used in 45 and 60% of the cases, respectively. For the more difficult cases, observer variation was smaller when the coronal and sagittal side windows were used. With the 'Big Brother' tool a method was developed to trace the delineation process. The differences between observers concerning the delineation style were large. This study led

  12. Evaluation of the Efficacy of Standardized Uptake Value (SUV-shape Scheme for Thyroid Volume Determination in Graves’ Disease: A Comparison with Ultrasonography

    Directory of Open Access Journals (Sweden)

    yangchun chen

    2017-01-01

    Full Text Available Objective(s: In this study, we aimed to evaluate the efficacy of thyroid volume measurement using 99mTc pertechnetate single-photon emission computed tomography (SPECT images, acquired by the standardized uptake value (SUV-shape scheme designed by our expert team.Methods: A total of 18 consecutive patients with Graves’ disease (GD were subjected to both ultrasonographic and 99mTc pertechnetate SPECT examinations of thyroid within a five-day interval. The volume of thyroid lobes and isthmus was measured by ultrasonography (US according to the ellipsoid volume equation. The total thyroid volume, determined as the sum of the volume of both lobes and isthmus, was recorded as TV-US (i.e., thyroid volume measured by US and set as the reference. The thyroid volume was defined according to our SUV-shape scheme and was recorded as TV-SS (i.e., thyroid volume determined by the SUV-shape scheme. The data were analyzed using the Bland-Altman plot, linear regression analysis, Spearman’s rank correlation, and paired t-test, if necessary.Results: The values of TV-SS (40.2±29.4 mL and TV-US (43.0±34.7 mL were not significantly different (t=0.813; P=0.43. The linear regression equation of the two values was determined as TV-US= 1.072 × TV-SS − 0.29(r=0.906; P

  13. The Effect of Local Anesthetic Volume Within the Adductor Canal on Quadriceps Femoris Function Evaluated by Electromyography

    DEFF Research Database (Denmark)

    Grevstad, Ulrik; Jæger, Pia; Kløvgaard, Johan

    2016-01-01

    BACKGROUND: Single-injection adductor canal block (ACB) provides analgesia after knee surgery. Which nerves that are blocked by an ACB and what influence-if any-local anesthetic volume has on the effects remain undetermined. We hypothesized that effects on the nerve to the vastus medialis muscle......L was used (P = 0.0001). No statistically significant differences were found between volume and effect on the vastus lateralis (P = 0.81) or in muscle strength (P = 0.15). CONCLUSIONS: For ACB, there is a positive correlation between local anesthetic volume and effect on the vastus medialis muscle. Despite...... (which besides being a motor nerve innervates portions of the knee) are volume-dependent. METHODS: In this assessor- and subject-blinded randomized trial, 20 volunteers were included. On 3 separate days, subjects received an ACB with different volumes (10, 20, and 30 mL) of lidocaine 1%. In addition...

  14. Cross-sectional and longitudinal evaluation of liver volume and total liver fat burden in adults with nonalcoholic steatohepatitis

    Science.gov (United States)

    Tang, An; Chen, Joshua; Le, Thuy-Anh; Changchien, Christopher; Hamilton, Gavin; Middleton, Michael S.; Loomba, Rohit; Sirlin, Claude B.

    2014-01-01

    Purpose To explore the cross-sectional and longitudinal relationships between fractional liver fat content, liver volume, and total liver fat burden. Methods In 43 adults with non-alcoholic steatohepatitis participating in a clinical trial, liver volume was estimated by segmentation of magnitude-based low-flip-angle multiecho GRE images. The liver mean proton density fat fraction (PDFF) was calculated. The total liver fat index (TLFI) was estimated as the product of liver mean PDFF and liver volume. Linear regression analyses were performed. Results Cross-sectional analyses revealed statistically significant relationships between TLFI and liver mean PDFF (R2 = 0.740 baseline/0.791 follow-up, P liver volume (R2 = 0.352/0.452, P liver volume change and liver mean PDFF change (R2 = 0.556, P liver mean PDFF change (R2 = 0.920, P liver volume change (R2 = 0.735, P Liver segmentation in combination with MRI-based PDFF estimation may be used to monitor liver volume, liver mean PDFF, and TLFI in a clinical trial. PMID:25015398

  15. An Evaluation of Elementary Career Education Based on Language Achievement, Mathematics Achievement, and Occupational Awareness in Lincoln County, West Virginia. Volume V of Volume I.

    Science.gov (United States)

    Olson, LeVene A.

    This document presents an evaluation of an exemplary project in career education limited to students in Grades 1 through 6 in the schools of Lincoln County, West Virginia. The project's objectives were to compare two groups of students on language achievement, mathematics achievement, and occupational awareness, an experimental group who had…

  16. Volatilization and oxidative artifacts of PM bound PAHs at low volume sampling (2): Evaluation and comparison of mitigation strategies effects.

    Science.gov (United States)

    Balducci, Catia; Cecinato, Angelo; Paolini, Valerio; Guerriero, Ettore; Perilli, Mattia; Romagnoli, Paola; Tortorella, Carmela; Nacci, Renato Michele; Giove, Aldo; Febo, Antonio

    2017-12-01

    The artifacts induced by oxidative degradation and volatilization were assessed with regards to determination of particulate atmospheric PAHs collected at low volume conditions (2.3 m3 h-1) according to the EU Reference Method EN 12341:2014. In order to evaluate the oxidative degradation, PAH measures carried out through collecting airborne particulate with and without ozone denuders were examined. Simultaneously, the influence of volatilization was investigated by comparing concentrations of PAHs in particulate samples collected over 24-h and 12-h using conventional instruments. Summer and winter/spring campaigns were carried out in order to assess the influence of environmental contour on the artifact processes. Oxidative degradation led to a general decrease of PAH concentrations in both periods; in particular, the highest losses were observed for benzo[a]pyrene and perylene reaching, in average, ca. 20%. In the summer, the effect of volatilization exceeded that of oxidative degradation for light PAHs up to benzo[e]pyrene. In the winter/spring time, the influence of both artifact typologies could be mitigated by splitting the normal 24-h collection interval starting at midnight into two 12-h intervals. A mitigation of the losses could even be obtained by fixing the start time sampling fixed at noon or in the first hours of the day. Finally, the feasibility of collecting PAHs through prolonged sampling (>1 month) at the flow rate of 1.1 L min-1 was preliminarily investigated. Results indicated that this approach is unsuitable for minimizing the oxidative artifacts. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Evaluation of the mandibular volume and correlating variables in patients affected by unilateral and bilateral cleft lip and palate: a cone-beam computed tomography study.

    Science.gov (United States)

    Celikoglu, Mevlut; Ucar, Faruk Izzet; Buyuk, Suleyman Kutalmış; Celik, Salih; Sekerci, Ahmet Ercan; Akin, Mehmet

    2016-09-01

    The aims of the present study were to evaluate the mandibular volume in patients affected by unilateral (UCLP) and bilateral cleft lip and palate (BCLP) and to compare the findings with a well-matched normal occlusion sample without cleft. The study sample consisted of 66 patients divided into UCLP (24 patients; mean age, 14.46 ± 3.24 years), BCLP (17 patients; mean age, 14.28 ± 2.85 years), and control (25 patients; mean age, 14.40 ± 2.81 years) groups. The volume of the mandible including the condyle and the roots of the teeth and craniofacial measurements were performed using cone-beam computed tomography and analyzed using the one-way variance analysis and post hoc Tukey's tests. Regression analyses were used to evaluate the relationships of the measurements and the mandibular volume. Patients affected by UCLP and BCLP had similar craniofacial features (p > 0.05), including decreased SNB, Co-A, Co-Gn, Co-Go, and Go-Gn and increased ANB and SN-MP measurements compared to the control group. Both UCLP and BCLP groups had decreased values of mandibular volume compared to the normal occlusion group, while these differences were found to be statistically insignificant (p > 0.05). Co-Go (Beta = 0.420; p = 0.014) and Co-Gn variables (Beta = 0.708; p = 0.045) were positively correlated with mandibular volume, while SNB (Beta = -0.669; p = 0.044) and SN-MP (Beta = -0.358; p = 0.049) variables were negatively correlated (R (2) = 60.3 and p = 0.000). Mandibular volume insignificantly differs in cleft patients (p > 0.05), and the variables of Co-Go, Co-Gn, SNB, and SN-MP significantly correlate with the volume. This article investigates mandibular volume in patients affected by UCLP and BCLP that has never been investigated in the literature. The present study showed that both UCLP and BCLP groups had insignificantly decreased values of mandibular volume compared to the normal occlusion group.

  18. Evaluation of occupant volume strength in conventional passenger railroad equipment : a thesis submitted by Michael E. Carolan

    Science.gov (United States)

    2008-05-31

    To ensure a level of occupant volume protection, passenger railway : equipment operating on mainline railroads in the United States must currently be : designed to resist an 800,000 pound compressive load applied statically to the : underframe. An al...

  19. Office of Technology Development`s Research, Development, Demonstration, Testing and Evaluation Mid-Year Program Review. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1994-08-01

    This document, Volume 2, presents brief summaries of programs being investigated at USDOE sites for waste processing, remedial action, underground storage tank remediation, and robotic applications in waste management.

  20. Effectiveness evaluation of two volumizing hyaluronic acid dermal fillers in a controlled, randomized, double-blind, split-face clinical study

    Directory of Open Access Journals (Sweden)

    Kerscher M

    2017-06-01

    Full Text Available Martina Kerscher,1 Karla Agsten,2 Maria Kravtsov,3 Welf Prager4 1Department of Cosmetic Science, University of Hamburg, 2SCIderm GmbH, Hamburg, Germany; 3Anteis S.A., Geneva, Switzerland; 4Prager & Partner Dermatologische Praxis, Hamburg, Germany Background: Enhancement of the midface can be achieved with volumizing hyaluronic acid (HA fillers.Objective: The objective of this study was to compare the safety and effectiveness of Cohesive Polydensified Matrix® 26 mg/mL HA gel (CPM-26 and Vycross® 20 mg/ml HA gel (VYC-20 in a controlled, randomized, evaluator-blind, split-face clinical study.Patients and methods: Subjects with moderate-to-severe malar volume loss on the Merz Aesthetics Scale (MAS received CPM-26 on one side and VYC-20 on the contralateral side of the face. Effectiveness assessments were performed by blinded evaluators including photographic and live MAS ratings and live Global Aesthetic Improvement Scale (GAIS ratings. Calculations of anatomical volume variations at month 3 (M3, month 6 (M6, month 12 (M12 and month 18 (M18 were also performed.Results: Non-inferiority of CPM-26 versus VYC-20 was demonstrated at M3 (primary end point based on MAS. GAIS rating showed that significantly more subjects had better improvement with CPM-26 than with VYC-20 at month 1, M3, M12 and M18 (p=0.0032, p=0.0074, p=0.0384 and p=0.0110, respectively. Standardized evaluation of volume variations from baseline to M3, M12 and M18 showed that CPM-26 created more volume augmentation at all time points, and the difference was significant at M3.Conclusion: CPM-26 was non-inferior to VYC-20 based on MAS ratings at M3 and demonstrated a favorable safety and effectiveness profile for midfacial volume enhancement with results lasting up to M18. Keywords: cohesive polydensified matrix, hyaluronic acid fillers, Belotero® Volume, Modélis® SHAPE, Juvéderm® VOLUMA®, volumizing

  1. Comparative evaluation of respiratory-gated and ungated FDG-PET for target volume definition in radiotherapy treatment planning for pancreatic cancer.

    Science.gov (United States)

    Kishi, Takahiro; Matsuo, Yukinori; Nakamura, Akira; Nakamoto, Yuji; Itasaka, Satoshi; Mizowaki, Takashi; Togashi, Kaori; Hiraoka, Masahiro

    2016-08-01

    The purpose of this study was to evaluate the usefulness of respiratory-gated positron emission tomography (4D-PET) in pancreatic cancer radiotherapy treatment planning (RTTP). Fourteen patients with 18F-fluorodeoxyglucose (FDG)-avid pancreatic tumours were evaluated between December 2013 and March 2015. Two sets of volumes were contoured for the pancreatic tumour of each patient. The biological target volume in three-dimensional RTTP (BTV3D) was contoured using conventional respiratory un-gated PET. The BTV3D was then expanded using population-based margins to generate a series of internal target volume 3D (ITV3D) values. The ITV 4D (ITV4D) was contoured using 4D-PET. Each of the five phases of 4D-PET was used for 4D contouring, and the ITV4D was constructed by summing the volumes defined on the five individual 4D-PET images. The relative volumes and normalized volumetric overlap were computed between ITV3D and ITV4D. On average, the FDG-avid tumour volumes were 1.6 (range: 0.8-2.3) fold greater in the ITV4D than in the BTV3D. On average, the ITV3D values were 2.0 (range: 1.1-3.4) fold larger than the corresponding ITV4D values. The ITV generated from 4D-PET can be used to improve the accuracy or reduce normal tissue irradiation compared with conventional un-gated PET-based ITV. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Separate Evaluation of the Ipsilateral and Contralateral MR Fetal Lung Volume in Patients With Congenital Diaphragmatic Hernia.

    Science.gov (United States)

    Hagelstein, Claudia; Burger-Scheidlin, Stefan; Weis, Meike; Weiss, Christel; Schoenberg, Stefan O; Schaible, Thomas; Neff, K Wolfgang

    2016-08-01

    Our study had two objectives. First, we separately evaluated observed-to-expected MR fetal lung volume (FLV) of lungs ipsilateral and contralateral to a congenital diaphragmatic hernia (CDH). Second, we compared the prognostic value of observed-to-expected MR FLV of the ipsilateral and contralateral lungs with that of observed-to-expected MR FLV of both lungs with respect to survival, need for extracorporeal membrane oxygenation (ECMO), and development of chronic lung disease (CLD). We evaluated observed-to-expected MR FLV of the lung ipsilateral to the diaphragmatic defect as well as in the contralateral lung in 107 fetuses with isolated CDH. ROC analysis and logistic regression analysis were performed to assess the prognostic value of the observed-to-expected MR FLV for association with outcome. In all fetuses with CDH, values in the ipsilateral (mean observed-to-expected MR FLV ± SD, 9.4% ± 9.6%) and the contralateral lung (mean observed-to-expected MR FLV, 48.9% ± 18.5%; p lungs and of the contralateral and ipsilateral lung revealed significant differences regarding survival (p lungs, the observed-to-expected MR FLV of the contralateral lung showed a slightly higher prognostic accuracy regarding survival (AUC = 0.859 vs 0.825) and development of CLD (AUC = 0.734 vs 0.732) and a similar prognostic accuracy regarding need for ECMO (AUC = 0.805 vs 0.826). Observed-to-expected MR FLV of the ipsilateral lung did not show good prognostic value regarding survival (AUC = 0.617), need for ECMO (AUC = 0.673), and development of CLD (AUC = 0.636). These AUCs were significantly smaller than the AUCs resulting from the observed-to-expected MR FLV of both lungs (each p lung (each p lungs compared with healthy fetuses. The observed-to-expected MR FLV of both lungs as well as of the lung contralateral to the CDH were reliable prenatal predictors of survival, need for ECMO, and development of CLD.

  3. Evaluation of endometrial and subendometrial vascularization and endometrial volume by 3-D power Doppler ultrasound and its relationship with age and pregnancy in intrauterine insemination cycles.

    Science.gov (United States)

    Engels, V; Sanfrutos, L; Pérez-Medina, T; Álvarez, P; Zapardiel, I; Bueno, B; Godoy-Tundidor, S; Bajo-Arenas, J M

    2011-01-01

    To measure endometrial volume and endometrial-subendometrial vascularization by 3-D power Doppler ultrasound in patients undergoing cycles of artificial insemination with ovarian stimulation, to evaluate their relationship with patients' age and pregnancy development. We included patients with primary and secondary infertility of one year of evolution. We measured vascular indexes and endometrial volume by 3-D power Doppler ultrasound. Seventy-nine consecutive cycles were studied. Endometrial volume average was 4.7 ± 2.66 ml. We did not find any difference between the endometrial volumes in women who did versus did not become pregnant (9 vs. 70 women, respectively). The endometrial vascular index was significantly higher in patients aged between 31 and 33 years old. In patients between the ages of 31 and 33, both the endometrial flow index (FI; p = 0.017) and the endometrial vascular FI (p = 0.013) were higher. At the subendometrial area, the vascular FI was lower in women older than 33 years old (p = 0.024), while the FI was higher in patients that achieved pregnancy (p = 0.047). Endometrial volumes were independent of pregnancy development. Endometrial and subendometrial vascularization FIs were significantly higher in younger women. The subendometrial FI was significantly higher in patients who achieved pregnancy. Copyright © 2011 S. Karger AG, Basel.

  4. Ozone measurements 2010. [EMEP Co-operative Programme for Monitoring and Evaluation of the Long-range Transmission of Air Pollutants in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Hjellbrekke, Anne-Gunn; Solberg, Sverre; Fjaeraa, Ann Mari

    2012-07-01

    From the Introduction: Ozone is a natural constituent of the atmosphere and plays a vital role in many atmospheric processes. However, man-made emissions of volatile organic compounds and nitrogen oxides have increased the photochemical formation of ozone in the troposphere. Until the end of the 1960s the problem was basically believed to be one of the big cities and their immediate surroundings. In the 1970s, however, it was found that the problem of photochemical oxidant formation is much more widespread. The ongoing monitoring of ozone at rural sites throughout Europe shows that episodes of high concentrations of ground-level ozone occur over most parts of the continent every summer. During these episodes the ozone concentrations can reach values above ambient air quality standards over large regions and lead to adverse effects for human health and vegetation. Historical records of ozone measurements in Europe and North America indicate that in the last part of the nineteenth century the values were only about half of the average surface ozone concentrations measured in the same regions during the last 10-15 years (Bojkov, 1986; Volz and Kley, 1988).The formation of ozone is due to a large number of photochemical reactions taking place in the atmosphere and depends on the temperature, humidity and solar radiation as well as the primary emissions of nitrogen oxides and volatile organic compounds. Together with the non-linear relationships between the primary emissions and the ozone formation, these effects complicates the abatement strategies for ground-level ozone and makes photochemical models crucial in addition to the monitoring data. The 1999 Gothenburg Protocol is designed for a joint abatement of acidification, eutrophication and ground-level ozone. It has been estimated that once the Protocol is implemented, the number of days with excessive ozone levels will be halved and that the exposure of vegetation to excessive ozone levels will be 44% down on 1990. The EMEP ozone data from 2010 are presented in this report, which aims to give a short summary of the measurement data. A complete set of data, including raw data, annual statistics and monthly means, can be downloaded from the web at http://ebas.nilu.no and at http://www.nilu.no/projects/ccc. (Author)

  5. Evaluation of flow volume and flow patterns in the patent false lumen of chronic aortic dissections using velocity-encoded cine magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Toshihisa; Watanabe, Shigeru; Sakurada, Hideki; Ono, Katsuhiro; Urano, Miharu; Hijikata, Yasuyoshi; Saito, Isao; Masuda, Yoshiaki [Chiba Univ. (Japan). School of Medicine

    2000-10-01

    In 21 patients with chronic aortic dissections and proven patent false lumens, the flow volume and flow patterns in the patent false lumens was evaluated using velocity-encoded cine magnetic resonance imaging (VENC-MRI) and the relationship between the flow characteristics and aortic enlargement was retrospectively examined. Flow patterns in the false lumen were divided into 3 groups: pattern A with primarily antegrade flow (n=6), pattern R with primarily retrograde flow (n=3), and pattern B with bidirectional flow (n=12). In group A, the rate of flow volume in the false lumen compared to the total flow volume in true and false lumens (%TFV) and the average rate of enlargement of the maximum diameter of the dissected aorta per year ({delta}D) were significantly greater than in groups R and B (%TFV: 74.1{+-}0.07 vs 15.2{+-}0.03 vs 11.8{+-}0.04, p<0.01; {delta}D: 3.62{+-}0.82 vs 0 vs 0.58{+-}0.15 mm/year, p<0.05, respectively). There was a significant correlation between %TFV and {delta}D (r=0.79, p<0.0001). Evaluation of flow volume and flow patterns in the patent false lumen using VENC-MRI may be useful for predicting enlargement of the dissected aorta. (author)

  6. An Open-Label Uncontrolled, Multicenter Study for the Evaluation of the Efficacy and Safety of the Dermal Filler Princess VOLUME in the Treatment of Nasolabial Folds

    Directory of Open Access Journals (Sweden)

    Daisy Kopera

    2015-01-01

    Full Text Available The dermal filler Princess VOLUME is a highly cross-linked, viscoelastic hyaluronic acid injectable gel implant used for aesthetic treatment. To evaluate the efficacy and safety of Princess VOLUME in the treatment of nasolabial folds, an open-label uncontrolled, multicenter study was conducted. Forty-eight subjects were recruited who had moderate to deep wrinkles, according to the Modified Fitzpatrick Wrinkle Scale (MFWS. Subjects received Princess VOLUME in both nasolabial folds at Day 0. Nasolabial fold severity was evaluated at 30, 90, 180, and 270 days after treatment, using the MFWS and the Global Aesthetic Improvement Scale (GAIS. Adverse events and treatment site reactions were recorded. Among the 48 subjects, 93.8% were female with a median age of 52 years. There were significant improvements (P<0.0001 in the MFWS scores at 30, 180, and 270 days after treatment compared with those at baseline, with a mean decrease of 1.484 (±0.408, 1.309 (±0.373, and 1.223 (±0.401, respectively; hence the primary endpoint was achieved and clinical efficacy demonstrated. Princess VOLUME was well tolerated, and most adverse events were injection site reactions of mild to moderate severity. Subject satisfaction (97.9%, subject recommendation of the treatment (93.6%, and investigators GAIS scores (97.9% improvement were high.

  7. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Functional modules F1--F8 -- Volume 2, Part 1, Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Greene, N.M.; Petrie, L.M.; Westfall, R.M.; Bucholz, J.A.; Hermann, O.W.; Fraley, S.K. [Oak Ridge National Lab., TN (United States)

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. The manual is divided into three volumes: Volume 1--for the control module documentation; Volume 2--for functional module documentation; and Volume 3--for documentation of the data libraries and subroutine libraries.

  8. Carbon dioxide insufflation for colonoscopy: evaluation of gas volume, abdominal pain, examination time and transcutaneous partial CO2 pressure.

    Science.gov (United States)

    Yamano, Hiro-o; Yoshikawa, Kenjirou; Kimura, Tomoaki; Yamamoto, Eiichirou; Harada, Eiji; Kudou, Toyoki; Katou, Ryusuke; Hayashi, Yasuko; Satou, Kentarou

    2010-12-01

    Insufflation with carbon dioxide (CO(2)) in colonoscopy has not been widely adopted and, consequently, limited data are available on insufflated gas volume and blood pCO(2). The aim of this study was to compare CO(2) and air as an insufflation agent in patients undergoing colonoscopy without sedation in terms of insufflated gas volume, pCO(2), pain and examination time. This was a randomized, double-blind, control trial. Consecutive patients presenting for colonoscopy, excluding those with lung or malignant disease, were randomized into two groups: insufflation with air or with CO(2), respectively. Insufflated gas volume, pain, pCO(2) and examination time were assessed. The study cohort comprised 120 patients (66 randomized to CO(2) group). No significant difference in insufflated gas volumes was found between the CO(2) and air groups. The mean pCO(2) measured before, during (the peak value) and 30 min after colonoscopy were 40, 43 and 40 mmHg, respectively, in both groups. The pain scores in the air group were significantly greater than those in the CO(2) group until 3 h after the examination. There was a significant faster cecal intubation time and a trend toward shorter examination time in the CO(2) group. The CO(2) gas volume used in our study (14.0 L) was much greater than that reported by others (8.3 L), but the pCO(2) values were still within the normal reference range, indicating the safety of CO(2) insufflation over a greater range of CO(2) gas volume. Among our patients, CO(2) insufflation was associated with relatively less pain and a shorter examination time. Based on our results, we recommend that CO(2) become the standard gas for insufflation in patients undergoing colonoscopy without sedation.

  9. Plants growing on contaminated and brownfield sites appropriate for use in Organisation for Economic Co-operation and Development terrestrial plant growth test.

    Science.gov (United States)

    Sinnett, Danielle E; Lawrence, Victoria K; Hutchings, Tony R; Hodson, Mark E

    2011-01-01

    The Organisation for Economic Co-operation and Development (OECD) terrestrial plant test is often used for the ecological risk assessment of contaminated land. However, its origins in plant protection product testing mean that the species recommended in the OECD guidelines are unlikely to occur on contaminated land. Six alternative species were tested on contaminated soils from a former Zn smelter and a metal fragmentizer with elevated concentrations of Cd, Cu, Pb, and Zn. The response of the alternative species was compared with that of two species recommended by the OECD: Lolium perenne (perennial ryegrass) and Trifolium pratense (red clover). Urtica dioica (stinging nettle) and Poa annua (annual meadowgrass) had low emergence rates in the control soil and so may be considered unsuitable. Festuca rubra (Chewings fescue), Holcus lanatus (Yorkshire fog), Senecio vulgaris (common groundsel), and Verbascum thapsus (great mullein) offer good alternatives to the OECD species. In particular, H. lanatus and S. vulgaris were more sensitive to the soils with moderate concentrations of Cd, Cu, Pb, and Zn than the OECD species. © 2010 SETAC.

  10. Scientific and Regulatory Policy Committee Review: Review of the Organisation for Economic Co-operation and Development (OECD) Guidance on the GLP Requirements for Peer Review of Histopathology.

    Science.gov (United States)

    Fikes, James D; Patrick, Daniel J; Francke, Sabine; Frazier, Kendall S; Reindel, James F; Romeike, Annette; Spaet, Robert H; Tomlinson, Lindsay; Schafer, Kenneth A

    2015-10-01

    In 2014, the Organisation for Economic Co-operation and Development (OECD) issued guidance no. 16, Guidance on the GLP Requirements for Peer Review of Histopathology. The stated purpose of the guidance document is "to provide guidance to pathologists, test facility management, study directors and quality assurance personnel on how the peer review of histopathology should be planned, managed, documented, and reported in order to meet Good Laboratory Practice (GLP) expectations and requirements." On behalf of and in collaboration with the global societies of toxicologic pathology, the Society of Toxicologic Pathology initiated a review of OECD guidance no. 16. The objectives of this review are to provide a unified interpretation of the guidance, to recommend compliant processes for organizations to implement, and to avoid inconsistent process adaptations across the industry. This review of the guidance document is the product of a global collaboration with other societies of toxicologic pathology and provides a section-by-section international consensus view and interpretation of the OECD guidance on peer review. © 2015 by The Author(s).

  11. Upstream open reading frames of the barley Mla13 powdery mildew resistance gene function co-operatively to down-regulate translation.

    Science.gov (United States)

    Halterman, Dennis A; Wise, Roger P

    2006-05-01

    SUMMARY To protect themselves against pathogen infection, plants have evolved multifarious defence mechanisms that include the production of antimicrobial compounds and hypersensitive cell death. This defence includes the regulation of expression of resistance proteins, which function to detect pathogen effectors and control the response. Barley Mla is one of several Ml genes that confer specific resistance to the powdery mildew fungus, Blumeria graminis f. sp. hordei. The Mla13 allele contains a long (523 nt) transcript leader region with three upstream open reading frames (uORFs) and two alternatively spliced introns. The lengths of the Mla13 uORFs, which encode up to 70 amino acid peptides, are directly influenced by the splicing of these introns. We have used in vivo and in vitro translation assays to show that Mla13 uORFs function co-operatively to down-regulate translation of the parent cistron up to 13-fold. However, resistance conferred by constitutively transcribed Mla appears to be unaffected by removal of these uORFs, signifying that a potential increase in MLA13 protein is innocuous to barley cells. In addition, cells that possess a predicted increase in MLA13 translation via over-expression and uORF mutation retain their requirement for RAR1, suggesting that this increase is not sufficient to overcome the concentration threshold required for activation of RAR1-independent resistance.

  12. Opportunities and Threats of Ukrainian Membership in WTO for Engineering under Conditions of Co-operation with EU Countries and Customs Union of Belarus, Kazakhstan and Russia

    Directory of Open Access Journals (Sweden)

    Kyzym Mykola O.

    2014-02-01

    Full Text Available The article considers consequences of the membership of Ukraine in the World Trade Organisation (WTO for the engineering industry when co-operating with the EU and CU (Customs Union of Belarus, Kazakhstan and Russia countries. It shows that, after Ukraine joined WTO, tariff rates for Ukrainian products reduced in general and liberalisation of access to the world market took place. Along with it, the internal market of Ukraine became more open for imported products. The article analyses the structure of export from Ukraine after joining WTO in the context of individual types of products. The article identifies changes that took place in the market of engineering products after Ukraine joined WTO. The article shows that by main indicators of economic security the engineering industry of Ukraine cannot be considered as stable and also that, after joining WTO, main indicators of economic security of the engineering industry of Ukraine have not improved. It analyses the structure of export and import of Ukrainian engineering products to EU, CU and other countries. It proves that the most topical for the Ukrainian engineering industry is the issue of realisation of the import-replacement potential and increase of competitiveness of domestic products. It considers the state and changes, which took place after Ukraine joined WTO, in car building. It identifies main problems of domestic car building. It analyses measures of the state programme of Ukraine on economic development.

  13. A Solid Earth educational module, co-operatively developed by scientists and high school teachers through the Scripps Classroom Connection GK12 Program

    Science.gov (United States)

    Ziegler, L. B.; van Dusen, D.; Benedict, R.; Chojnacki, P. R.; Peach, C. L.; Staudigel, H.; Constable, C.; Laske, G.

    2010-12-01

    The Scripps Classroom Connection, funded through the NSF GK-12 program, pairs local high school teachers with Scripps Institution of Oceanography (SIO) graduate students in the earth and ocean sciences for their mutual professional development. An integral goal of the program is the collaborative production of quality earth science educational modules that are tested in the classroom and subsequently made freely available online for use by other educators. We present a brief overview of the program structure in place to support this goal and illustrate a module that we have developed on the Solid Earth & Plate Tectonics for a 9th grade Earth Science classroom. The unit includes 1) an exercise in constructing a geomagnetic polarity timescale which exposes students to authentic scientific data; 2) activities, labs, lectures and worksheets that support the scientific content; and 3) use of online resources such as Google Earth and interactive animations that help students better understand the concepts. The educational unit is being implemented in two separate local area high schools for Fall 2010 and we will report on our experiences. The co-operative efforts of teachers and scientists lead to educational materials which expose students to the scientific process and current science research, while teaching basic concepts using an engaging inquiry-based approach. In turn, graduate students involved gain experience communicating their science to non-science audiences.

  14. Stereological estimates of nuclear volume and other quantitative variables in supratentorial brain tumors. Practical technique and use in prognostic evaluation

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Braendgaard, H; Chistiansen, A O

    1991-01-01

    the practical technique. The continuous variables were correlated with the subjective, qualitative WHO classification of brain tumors, and the prognostic value of the parameters was assessed. Well differentiated astrocytomas (n = 14) had smaller estimates of the volume-weighted mean nuclear volume and mean......p approximately 0.05, respectively). Age above the median and short duration of symptoms were significantly associated with short survival (2p = 0.01). Further investigations of larger series of patients are needed to define the clinical usefulness of these objective, reproducible, and quantitative...

  15. Evaluation of the partial volume effect in the activity quantification in PET/CT images; Avaliacao do efeito de volume parcial na quantificacao de atividade em imagens de PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Krempser, Alexandre R., E-mail: krempser@peb.ufrj.br [Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE/UFRJ), RJ (Brazil). Instituto Alberto Luiz Coimbra. Programa de Engenharia Biomedica; Oliveira, Silvia M. Velasques de [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Almeida, Sergio A. de [Hospital Samaritano, Rio de Janeiro, RJ (Brazil). Centro de Imagens PET/CT

    2012-08-15

    The aim of this work was to evaluate the influence of partial volume effect (PVE) in the quantification of activity in images of a PET-CT scanner and its ability to identify lesions. Recovery coefficients were calculated using a phantom containing 12 cylinders with diameters between 4 and 30 mm and a National Electrical Manufactures Association scattering phantom, both fillable with known concentrations of {sup 18}F. The images were acquired for acquisition time of 3 and 5 minutes, and cylinder to background ratio of n=8:1 and n=4:1. The recovery coefficients were calculated between 0.01 and 0.91 depending on the diameter. Significant variations were not found in function of image acquisition parameters. Errors in the activity quantification above 70% were found for cylinders with diameters smaller than 10 mm. The cylinders with diameters smaller than 8 mm were not identified in the images. The phantoms were adequate for PVE evaluation in the PET/CT images. The PVE had the greatest impact on the cylinders with diameters of 6 and 4 mm. It's necessary to use partial volume correction techniques in the images in order to increase the quantitative accuracy of the studied equipment. (author)

  16. An Evaluation of the Mulligan Stew 4-H Television Series for Extension Service, USDA. Volume I: Executive Summary.

    Science.gov (United States)

    Shapiro, Sydelle Stone; And Others

    Conducted on over 3,000 fourth, fifth, and sixth grade children in six states, this study documents changes in nutrition-related knowledge and behaviors which can be related to participating in the Mulligan Stew televsion series. This volume contains a summary of the findings of the study and recommendations. After participating in the series,…

  17. An Evaluation of the Mulligan Stew 4-H Television Series for Extension Service, USDA. Volume II: Report of the Study.

    Science.gov (United States)

    Shapiro, Sydelle Stone; And Others

    Conducted on over 3,000 fourth, fifth, and sixth grade children in six states, this study documents changes in nutrition-related knowledge and behaviors which can be related to participating in the Mulligan Stew television series. This volume is a detailed elaboration of the study findings as well as a description of the study design,…

  18. An Evaluation of the Mulligan Stew 4-H Television Series for Extension Service, USDA. Volume III: Case Studies.

    Science.gov (United States)

    Abt Associates, Inc., Cambridge, MA.

    Conducted on over 3,000 fourth, fifth, and sixth grade children in six states, this study documents changes in nutrition-related knowledge and behaviors which can be related to participating in the Mulligan Stew television series. The case studies which comprise this volume function as a brief organizational analysis of the Mulligan Stew effort at…

  19. Stereological estimation of nuclear volume and other quantitative histopathological parameters in the prognostic evaluation of supraglottic laryngeal squamous cell carcinoma

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Bennedbaek, O; Pilgaard, J

    1989-01-01

    The aim of this study was to investigate various approaches to the grading of malignancy in pre-treatment biopsies from patients with supraglottic laryngeal squamous cell carcinoma. The prospects of objective malignancy grading based on stereological estimation of the volume-weighted mean nuclear...

  20. Leaving Education Early: Putting Vocational Education and Training Centre Stage. Volume II: Evaluating Policy Impact. Cedefop Research Paper. No 58

    Science.gov (United States)

    Cedefop - European Centre for the Development of Vocational Training, 2016

    2016-01-01

    This Cedefop study focuses on the contribution that vocational education and training (VET) can make to reducing early leaving from education and training (ELET). Published in two volumes, the first is dedicated to understanding better the learning pathways of young students, providing measurements of early leaving in VET, and understanding the…

  1. Role of Doppler ultrasonography evaluation of superior mesenteric artery flow volume in the assessment of Crohn's disease activity

    Directory of Open Access Journals (Sweden)

    Fabiana Paiva Martins

    2013-09-01

    Full Text Available Objective To investigate superior mesenteric artery flow measurement by Doppler ultrasonography as a means of characterizing inflammatory activity in Crohn's disease. Materials and Methods Forty patients were examined and divided into two groups – disease activity and remission – according to their Crohn's disease activity index score. Mean superior mesenteric artery flow volume was calculated for each group and correlated with Crohn's disease activity index score. Results The mean superior mesenteric artery flow volume was significantly greater in the patients with active disease (626 ml/min ± 236 × 376 ml/min ± 190; p = 0.001. As a cut off corresponding to 500 ml/min was utilized, the superior mesenteric artery flow volume demonstrated sensitivity of 83% and specificity of 82% for the diagnosis of Crohn's disease activity. Conclusion The present results suggest that patients with active Crohn's disease have increased superior mesenteric artery flow volume as compared with patients in remission. Superior mesenteric artery flow measurement had a good performance in the assessment of disease activity in this study sample.

  2. Field evaluation of indoor thermal fog and ultra-low volume applications for control of Aedes aegypti, in Thailand

    Science.gov (United States)

    Efficacies of a hand-held thermal fogger (PatriotTM) and hand-held Ultra-low volume (ULV) sprayer (TwisterTM) with combinations of two different adulticides and an insect growth regulator (pyriproxyfen) were field assessed and compared for their impact on reducing dengue vector populations in Thaila...

  3. Evaluation of left ventricular function and volumes in patients with ischaemic cardiomyopathy: gated single-photon emission computed tomography versus two-dimensional echocardiography

    Energy Technology Data Exchange (ETDEWEB)

    Vourvouri, E.C.; Poldermans, D.; Sianos, G.; Sozzi, F.B.; Schinkel, A.F.L.; Sutter, J. de; Roelandt, J.R.T.C. [Dept. of Cardiology, Erasmus Medical Center Rotterdam (Netherlands); Bax, J.J. [Dept. of Cardiology, Leiden Univ. Medical Center (Netherlands); Parcharidis, G. [Dept. of Cardiology, AHEPA Univ. Hospital, Thessaloniki (Greece); Valkema, R. [Dept. of Nuclear Medicine, Erasmus Medical Center Rotterdam (Netherlands)

    2001-11-01

    The objective of this study was to perform a head-to-head comparison between two-dimensional (2D) echocardiography and gated single-photon emission computed tomography (SPET) for the evaluation of left ventricular (LV) function and volumes in patients with severe ischaemic LV dysfunction. Thirty-two patients with chronic ischaemic LV dysfunction [mean LV ejection fraction (EF) 25%{+-}6%] were studied with gated SPET and 2D echocardiography. Regional wall motion was evaluated by both modalities and scored by two independent observers using a 16-segment model with a 5-point scoring system (1= normokinesia, 2= mild hypokinesia, 3= severe hypokinesia, 4= akinesia and 5= dyskinesia). LVEF and LV end-diastolic and end-systolic volumes were evaluated by 2D echocardiography using the Simpson's biplane discs method. The same parameters were calculated using quantitative gated SPET software (QGS, Cedars-Sinai Medical Center). The overall agreement between the two imaging modalities for assessment of regional wall motion was 69%. The correlations between gated SPET and 2D echocardiography for the assessment of end-diastolic and end-systolic volumes were excellent (r=0.94, P<0.01, and r=0.96, P<0.01, respectively). The correlation for LVEF was also good (r=0.83, P<0.01). In conclusion: in patients with ischaemic cardiomyopathy, close and significant relations between gated SPET and 2D echocardiography were observed for the assessment of regional and global LV function and LV volumes; gated SPET has the advantage that it provides information on both LV function/dimensions and perfusion. (orig.)

  4. Evaluation of potential severe accidents during low power and shutdown operations at Surry, Unit 1: Evaluation of severe accident risk during mid-loop operations. Volume 6, Part 2: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Jo, J.; Lin, C.C.; Neymotin, L.; Mubayi, V. [Brookhaven National Lab., Upton, NY (United States)

    1995-05-01

    The objectives are to assess the risks of severe accidents initiated during plant operational states other than full power operation and to compare the estimated core damage frequencies, important accident sequences and other qualitative and quantitative results with those accidents initiated during full power operation. In phase 2, mid-loop operation was selected as the plant configuration to be analyzed. Volume 1 summarizes the results of the study. The scope of the level-1 study includes plant damage state analyses, and uncertainty analysis. The internal event analysis is documented in Volume 2. The internal fire and internal flood analysis are documented in Volumes 3 and 4, respectively. A separate study on seismic analysis, documented in Volume 5, was performed for the NRC by Future Resources Associated, Inc. A phased approach was used in the level 2/3 PRA program, however both phases addressed the risk from only mid-loop operation. The first phase of the level 2/3 PRA was initiated in late 1991 and consisted of an Abridged Risk Study. This study was completed in May 1992 and was focused on accident progression and consequences, conditional on core damage. Phase 2 is a more detailed study in which an evaluation of risk during mid-loop operation was performed. The results of the phase 2 level 2/3 study are the subject of this volume of NUREG/CR-6144, Volume 6. This report, Volume 6, Part 2, consists of five appendices containing supporting information for: the PDS (plant damage state) analysis; the accident progression analysis; the source term analysis; the consequence analysis; and the Melcor analysis. 73 figs., 21 tabs.

  5. Ecological evaluation of proposed discharge of dredged material from Oakland Harbor into ocean waters (Phase 3 B of -42-foot project). Volume 2, Appendixes

    Energy Technology Data Exchange (ETDEWEB)

    Kohn, N.P.; Ward, J.A.; Mayhew, H.L.; Word, J.Q.; Barrows, E.S.; Goodwin, S.M.; Lefkovitz, L.F. [Battelle/Marine Sciences Lab., Sequim, WA (United States)

    1992-06-01

    The Water Resources Development Act of 1986 (Public Law 99-662) authorized the US Army Corps of Engineers (USACE) San Francisco District, to deepen and widen the navigational channels of the Oakland Inner and Outer Harbors to accommodate deeper-draft vessels. The USACE is considering several disposal options for the dredged material removed during these channel improvements including open-water disposal. Dredged material proposed for open-water disposal must be evaluated to determine the potential impacts of the disposal activity on the water column and disposal site environments. The USACE requested that Battelle/Marine Sciences Laboratory (MSL) conduct studies to evaluate open-water disposal options for Oakland Harbor sediments. This request developed into the Oakland Harbor Phase III Program. This is Volume 2 of a two-volume report that presents information gathered to determine the suitability of ocean disposal of sediments dredged from Oakland Harbor. This volume contains the Appendixes (A through N), which provide details of the data analyses and full presentation of the data and results.

  6. Comparison of dual-source 64-slice adenosine stress CT perfusion with stress-gated SPECT-MPI for evaluation of left ventricular function and volumes.

    Science.gov (United States)

    Uthamalingam, Shanmugam; Gurm, Gagandeep S; Sidhu, Manavjot S; Verdini, Daniel J; Vorasettakarnkij, Yongkasem; Engel, Leif-Christopher; Blankstein, Ron; Mamuya, Wilfred S; Hoffman, Udo; Brady, Thomas J; Cury, Ricardo C; Ghoshhajra, Brian B

    2012-01-01

    Evaluation of left ventricular (LV) volumes and ejection fraction (LVEF) represent important components of pharmacologic stress imaging with either myocardial CT perfusion (CTP) or gated single-photon emission CT (SPECT) myocardial perfusion imaging (SPECT-MPI). We compared measurements of left ventricular function and volumes obtained with CTP and SPECT-MPI. Forty-seven patients (mean age, 62 ± 11 years; male, n = 39) underwent stress CTP and SPECT-MPI. LVEF (in %), end-systolic volume (ESV; in mL), and end-diastolic volume (EDV; in mL) derived from stress CTP images were compared with SPECT-MPI. Stress CTP was in good agreement with SPECT-MPI for quantification of LVEF (r = 0.91), EDV (r = 0.75), and ESV (r = 0.83; all P stress CTP (66% ± 17%) was similar to SPECT-MPI (64% ± 15%). Similar values were also derived for mean EDV (123 ± 30 mL vs 120 ± 34 mL) and ESV (44 ± 28 mL vs 51 ± 34 mL) for CTP and SPECT-MPI, respectively. Good agreement was also shown between both techniques for the assessment of regional wall motion with identical wall motion scores in 95.3% of the segments (κ = 0.79). LVEF and LV volume parameters as determined by dual-source 64-slice adenosine stress CTP show a high correlation with values obtained with stress-gated SPECT-MPI. Copyright © 2012 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

  7. Evaluation of potential severe accidents during low power and shutdown operations at Surry: Unit 1, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Chu, T.L.; Pratt, W.T. [eds.; Musicki, Z. [Brookhaven National Lab., Upton, NY (United States)

    1995-10-01

    This document contains a summarization of the results and insights from the Level 1 accident sequence analyses of internally initiated events, internally initiated fire and flood events, seismically initiated events, and the Level 2/3 risk analysis of internally initiated events (excluding fire and flood) for Surry, Unit 1. The analysis was confined to mid-loop operation, which can occur during three plant operational states (identified as POSs R6 and R10 during a refueling outage, and POS D6 during drained maintenance). The report summarizes the Level 1 information contained in Volumes 2--5 and the Level 2/3 information contained in Volume 6 of NUREG/CR-6144.

  8. Stereological estimates of nuclear volume in the prognostic evaluation of primary flat carcinoma in situ of the urinary bladder

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Jacobsen, F

    1991-01-01

    Primary, flat carcinoma in situ of the urinary bladder is rare and its behaviour is unpredictable. The aim of this retrospective study was to obtain base-line data and investigate the prognostic value of unbiased, stereological estimates of the volume-weighted mean nuclear volume, nuclear vv, in 78...... bladder biopsies from 22 patients with primary flat carcinoma in situ (Bergkvist grades III-IV). On average, nuclear vv was 77 microns 3 in nine biopsies with morphologically normal urothelium, 292 microns 3 in 56 isolated primary lesions and 266 microns 3 in lesions of luminal urothelium in 13 biopsies......, quantitative information, but their prognostic value in patients with primary flat carcinoma in situ of the bladder needs further clarification in larger data bases....

  9. Evaluation of Excess Free Volume and Internal Pressure in Binary Mixtures of Methyl Methacrylate(MMA with Alcohols

    Directory of Open Access Journals (Sweden)

    R. Vadamalar

    2009-01-01

    Full Text Available Methyl methacrylate (MMA is an important monomer attracting the attention of industrialists and scientists because of its various applications and reactivity. The knowledge of thermodynamic and transport properties of MMA in alcohols and other organic solvents is useful in industrial processes. Ultrasonic and viscometric parameters offer simple, easy and accurate ways for calculating several physical parameters which throw light on molecular interactions in solutions. In this paper, the interactions of two alcohols; tert-butanol and iso-butanol with MMA are reported for the first time. Comparison has been made on the interactive nature of the two alcohols. Computation of free volume, internal pressure and excess free volume has been made for the entire concentration range. Existence of mesomeric effects of MMA is clearly seen and the role of structure of alcohols is observed.

  10. Quality of type 2 diabetes management in the states of the Co-operation Council for the Arab States of the Gulf: a systematic review.

    Directory of Open Access Journals (Sweden)

    Layla Alhyas

    Full Text Available Type 2 diabetes mellitus is a growing, worldwide public health concern. Recent growth has been particularly dramatic in the states of The Co-operation Council for the Arab States of the Gulf (GCC, and these and other developing economies are at particular risk. We aimed to systematically review the quality of control of type 2 diabetes in the GCC, and the nature and efficacy of interventions. We identified 27 published studies for review. Studies were identified by systematic database searches. Medline and Embase were searched separately (via Dialog and Ovid, respectively; 1950 to July 2010 (Medline, and 1947 to July 2010 (Embase on 15/07/2009. The search was updated on 08/07/2010. Terms such as diabetes mellitus, non-insulin-dependent, hyperglycemia, hypertension, hyperlipidemia and Gulf States were used. Our search also included scanning reference lists, contacting experts and hand-searching key journals. Studies were judged against pre-determined inclusion/exclusion criteria, and where suitable for inclusion, data extraction/quality assessment was achieved using a specifically-designed tool. All studies wherein glycaemic-, blood pressure- and/or lipid- control were investigated (clinical and/or process outcomes were eligible for inclusion. No limitations on publication type, publication status, study design or language of publication were imposed. We found the extent of control to be sub-optimal and relatively poor. Assessment of the efficacy of interventions was difficult due to lack of data, but suggestive that more widespread and controlled trial of secondary prevention strategies may have beneficial outcomes. We found no record of audited implementation of primary preventative strategies and anticipate that controlled trial of such strategies would also be useful.

  11. Prevalence of type 2 diabetes in the States of the co-operation council for the Arab States of the Gulf: a systematic review.

    Directory of Open Access Journals (Sweden)

    Layla Alhyas

    Full Text Available AIMS: The recent and ongoing worldwide expansion in prevalence of Type 2 Diabetes (T2DM is a considerable risk to individuals, health systems and economies. The increase in prevalence has been particularly marked in the states of the Co-operation Council for the Arab States of the Gulf (GCC, and these trends are set to continue. We aimed to systematically review the current prevalence of T2DM within these states, and also within particular sub-populations. METHODS: We identified 27 published studies for review. Studies were identified by systematic database searches. Medline and Embase were searched using terms such as diabetes mellitus, non-insulin-dependent, hyperglycemia, prevalence, epidemiology and Gulf States. Our search also included scanning reference lists, contacting experts and hand-searching key journals. Studies were judged against pre-determined inclusion and exclusion criteria, and where suitable for inclusion, data extraction and quality assessment was achieved using a specifically-designed tool. All studies where prevalence of diabetes was investigated were eligible for inclusion. The inclusion criteria required that the study population be of a GCC country, but otherwise all ages, sexes and ethnicities were included, resident and migrant populations, urban and rural, of all socioeconomic and educational backgrounds. No limitations on publication type, publication status, study design or language of publication were imposed. However, we did not include secondary reports of data, such as review articles without novel data synthesis. CONCLUSIONS: The prevalence of T2DM is an increasing problem for all GCC states. They may therefore benefit to a relatively high degree from co-ordinated implementation of broadly consistent management strategies. Further study of prevalence in children and in national versus expatriate populations would also be useful.

  12. Co-operativity among defect sites in AnO2+ and An4O9 (An = U, Np or Pu)

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Anders David [Los Alamos National Laboratory; Lezama Pacheco, Juan [Los Alamos National Laboratory; Uberuaga, Blas P [Los Alamos National Laboratory; Conradson, Steven D [Los Alamos National Laboratory

    2008-01-01

    Actinide dioxides derived from the AnO{sub 2} fluorite lattice are of high technological relevance due to their application in nuclear reactor fuels. Oxidation of AnO{sub 2} compounds emerges as a central theme in fuel fabrication, reactor operation, long-term storage forms for both spent fuels and surplus weapons materials, and environmental actinide migration. In this paper, we use density functional theory calculations to study the oxidation of uranium, neptunium and plutonium dioxides, AnO{sub 2} (An = U, Np or Pu), in O{sub 2} and O{sub 2}/H{sub 2}O environments. We pay particular attention to the formation of oxygen clusters (co-operativity) in AnO{sub 2+x} and how this phenomenon govern oxidation thermodynamics and the development of ordered An{sub 4}O{sub 9} compounds. The so-called split di-interstitial, which is composed of two nearest neighbor octahedral oxygen interstitials that are distorted in such a way that they dislocate one regular fluorite lattice oxygen ion to form a cluster of triangular geometry, is predicted to be the fundamental building block of the most stable cluster configurations. We also identify how the formation of oxygen defect clusters and the degree of oxidation in AnO{sub 2+x} are both governed by the characer of the An-5f to excess O-2p charger transfer, i.e. the charge transfer to the O-2p orbitals of the interstitial-like (+x) ions, and the ability of the excess O-2p orbitals to hybridize with regular fluorite lattice ions.

  13. Nanosatellites for Interplanetary Exploration : Missions of Co-Operation and Exploration to Mars, Exo-Moons and other worlds in the Solar System

    Science.gov (United States)

    Ravi, Aditya; Radhakrishnan, Arun

    2016-07-01

    The last decade has borne witness to a large number of Nano-satellites being launched.This increasing trend is mainly down to the advancements in consumer electronics that has played a crucial role in increasing the potential power available on board for mission study and analysis whilst being much smaller in size when compared to their satellite counterparts. This overall reduction in size and weight is a crucial factor when coupled with the recent innovations in various propulsion systems and orbital launch vehicles by private players has also allowed the cost of missions to brought down to a very small budget whilst able to retain the main science objectives of a dedicated space Missions. The success of first time missions such as India's Mars Orbiter Mission and the upcoming Cube-Sat Mission to Mars has served as a catalyst and is a major eye-opener on how Interplanetary missions can be funded and initiated in small time spans. This shows that Interplanetary missions with the main objective of a scientific study can be objectified by using Dedicated Nano-satellite constellations with each satellite carrying specific payloads for various mission parameters such as Telemetry, Observation and possible small lander payloads for studying the various Atmospheric and Geo-Physical parameters of a particular object with-out the requirement of a very long term expensive Spacecraft Mission. The association of Major Universities and Colleges in building Nano and-satellites are facilitating an atmosphere of innovation and research among students in a class-room level as their creative potential will allow for experiments and innovation on a scale never imagined before. In this paper, the Author envisions the feasibility of such low cost Nano satellite missions to various bodies in the solar system and how Nano satellite partnerships from universities and space agencies from around the world could foster a new era in diplomacy and International Co-operation.

  14. Barriers to Integration of Immigrants and Integration Policy in the Czech Republic with Focus on Stakeholders and Their Co-operation

    Directory of Open Access Journals (Sweden)

    Miroslava Rákoczyová

    2011-04-01

    Full Text Available Social integration of migrants and related social work with this target group is increasingly becoming a focus of the enlarged conception of social policies in advanced economies. While immigration policy is often defined and shaped at a national level, its effects influence the lives of migrants and, consequently, also the host society, particularly at the regions and localities, where this policy is confronted with the specifics of the measures in other policy areas. Integration policies at the local level are created and implemented by a wide range of stakeholders, which places considerable demands on the mutual coordination and co-operation to achieve maximum efficiency of services provided. In the Czech Republic, coordination among different actors is still under-developed. Non-governmental organizations, which are oriented towards specific needs of foreigners, are generally considered to be the principal actors in the delivery of services to and social work with migrants. Public institutions’ competences are usually limited to the exercise of specific services defined by the legislation. Yet the cooperation between actors from among representatives of government and nonprofit organizations is not based on equal partnership. Based on qualitative interviews with the key stakeholders of social integration in the Czech Republic, this study aims to provide some insight into strategies for the integration of foreigners charged with activities of local actors with special emphasis on the role of NGOs in this process. Moreover, the authors try to highlight some barriers of collaboration between the actors, and the risk of inefficient allocation of resources to support social services for migrants.

  15. Decision Support Requirements in a Unified Life Cycle Engineering (ULCE) Environment. Volume 1. An Evaluation of Potential Research Directions.

    Science.gov (United States)

    1988-05-01

    lbn Cupmis lbs O pbis.w u(c) Wmi lam. ai hine I IuNsad mmm hislm. MA Ripi loi we I ft by .lii. peak of sm"pai emit Inkl hg wk. Peps =r milu lb a eIs lbd...David Owen of IDA. Section I of this volume was written by Professor Robert Kuenne. * ° S V U. U .~J. ~ ’ I! CONTENTS PREFACE... v ACRONYMS AND ABBREVIATIONS ......................................................... xi EXECUTIVE SUMMARY

  16. Evaluation of right ventricular volume and function by 2D and 3D echocardiography compared to MRI

    DEFF Research Database (Denmark)

    Kjaergaard, Jesper; Petersen, Claus Leth; Kjaer, Andreas

    2005-01-01

    : Thirty-four subjects with (a) prior inferior ST-elevation myocardial infarction (n=17), (b) a history of pulmonary embolism and persistent dyspnea (n=7) or (c) normal subjects (n=10) had 2D and 3D echocardiography, SPECT and MRI within 24h. End-diastolic volume and peak tricuspid regurgitation velocity...... were increased in patients with a history of pulmonary embolism compared to healthy subjects, 130+/-26 ml vs. 94+/-26 ml, P

  17. Evaluation By Remote Sensing Of The Withdrawn Water Volume From The Aquifer System Of The Spatientrional Sahara

    Directory of Open Access Journals (Sweden)

    Ahmed Kadria

    2017-08-01

    Full Text Available The present report shows the contribution of remote sensing to estimate the volume of water withdrawn from aquifers for a semi-arid or arid climate such as that in our study area the Aquifer System of Spatientrional Sahara. The vegetation area was firstly estimated from a spatial distribution of vegetation indices from the MOD13Q1 product of the MODIS sensor for a period from 2001 to 2011 by an algorithm highlighting the pixels in the red and the infrared. Its on average almost constant at 500 km2 for all the years. Furthermore evapotranspiration was defined spatially and statistically by the MOD16A2 product on the whole basin for 2011. The statistics are derived from an algorithm ensuring the logic based on the Penman-Monteith equation. These statistics regarding the area of vegetation gave the annual total volume of withdrawn water because this volume is evaporated in the absence of rainfall in the water balance and the depth of the basin does not allow it to vary in the grounds level. There was extraction more than 25 billion meters-cube. This means that the enormity of the consumption that is indeed a few hundred m3s. It presents a serious risk of salinity and flow reversal towards the sea. Such a calculation is developed depending on remote sensing elements such as the spatial and temporal resolutions.

  18. In-vivo near-infrared optical imaging of growing osteosarcoma cell lesions xenografted in mice: dual-channel quantitative evaluation of volume and mineralization.

    Science.gov (United States)

    Nakayama, Hitoshi; Kawase, Tomoyuki; Okuda, Kazuhiro; Wolff, Larry F; Yoshie, Hiromasa

    2011-11-01

    In a previous study using a rodent osteosarcoma-grafted rat model, in which cell-dependent mineralization was previously demonstrated to proportionally increase with growth, we performed a quantitative analysis of mineral deposit formation using (99m)Tc-HMDP and found some weaknesses, such as longer acquisition time and narrower dynamic ranges (i.e. images easily saturated). The recently developed near-infrared (NIR) optical imaging technique is expected to non-invasively evaluate changes in living small animals in a quantitative manner. To test the feasibility of NIR imaging with a dual-channel system as a better alternative for bone scintigraphy by quantitatively evaluating mineralization along with the growth of osteosarcoma lesions in a mouse-xenograft model. The gross volume and mineralization of osteosarcoma lesions were evaluated in living mice simultaneously with dual-channels by NIR dye-labeled probes, 2-deoxyglucose (DG) and pamidronate (OS), respectively. To verify these quantitative data, retrieved osteosarcoma lesions were then subjected to ex-vivo imaging, weighing under wet conditions, microfocus-computed tomography (μCT) analysis, and histopathological examination. Because of less scattering and no anatomical overlapping, as generally shown, specific fluorescence signals targeted to the osteosarcoma lesions could be determined clearly by ex-vivo imaging. These data were well positively correlated with the in-vivo imaging data (r > 0.8, P 0.8, P < 0.02) were observed between DG accumulation and tumor gross volume and between OS accumulation and mineralization volume. This in-vivo NIR imaging technique using DG and OS is sensitive to the level to simultaneously detect and quantitatively evaluate the growth and mineralization occuring in this type of osteosarcoma lesions of living mice without either invasion or sacrifice. By possible mutual complementation, this dual imaging system might be useful for accurate diagnosis even in the presence of

  19. Evaluation and Ranking of Geothermal Resources for Electrical Generation or Electrical Offset in Idaho, Montana, Oregon and Washington. Volume II.

    Energy Technology Data Exchange (ETDEWEB)

    Bloomquist, R. Gordon

    1985-06-01

    This volume contains appendices on: (1) resource assessment - electrical generation computer results; (2) resource assessment summary - direct use computer results; (3) electrical generation (high temperature) resource assessment computer program listing; (4) direct utilization (low temperature) resource assessment computer program listing; (5) electrical generation computer program CENTPLANT and related documentation; (6) electrical generation computer program WELLHEAD and related documentation; (7) direct utilization computer program HEATPLAN and related documentation; (8) electrical generation ranking computer program GEORANK and related documentation; (9) direct utilization ranking computer program GEORANK and related documentation; and (10) life cycle cost analysis computer program and related documentation. (ACR)

  20. Parts on Demand: Evaluation of Approaches to Achieve Flexible Manufacturing Systems for Navy Partson Demand. Volume 1

    Science.gov (United States)

    1984-02-01

    computer-aided technol- ogy which capitalizes upon improved information handling and manufacturing process- ing capabilities. The use of computer-aided...COST $2,938.91 ORDERING COSTo 309.89 x (41.25 x 4) 51131.85 . $11.019.79 8 x (309.89) x 25.563 4.64 * .28 x 10,496.17 TOTAL YEARLY...to capitalize upon advanced technology to improve low volume production capability. CP/5A-39 60 q 60 -- -.. Coll) 0 LL. A.)) I-L En LL. *c 2c C- 61J

  1. Evaluation of the anterior ethmoidal artery by 3D dual volume rotational digital subtraction angiography and native multidetector CT with multiplanar reformations. Initial findings.

    Science.gov (United States)

    Pandolfo, Ignazio; Vinci, Sergio; Salamone, Ignazio; Granata, Francesca; Mazziotti, Silvio

    2007-06-01

    Our purpose is to codify the anterior ethmoidal artery (AEA) course and its relationship with adjacent structures. Twenty patients with cerebrovascular disease underwent selective internal carotid dual volume angiography. Fusion of the vascular and bony images was obtained successively on a second console. MDCT of the cranium was performed in all patients. To identify the AEA course, multiplanar CT reformations were obtained. In all cases the entry-point of AEA and its course were identified by means of dual volume angiography. The information was confirmed by MDCT. In a second phase, we studied another 78 patients affected by inflammatory disease and polyposis only by means of MDCT, in order to confirm the previous data obtained by comparison between angiography and MDCT. In this second phase, 110/156 vessels were indirectly detected by means of visualization of the ethmoidal entry point. In the remaining cases, AEA was directly shown due to integrity of the thin ethmoidal bone lamellae or bony canal. Dual volume angiography is essential to identify the course of the AEA (standard of reference for the interpretation of CT). In patients with benign rhinosinusal pathology, where invasivity techniques are not justified, MPR reconstructions were of pivotal importance in the evaluation of the course of the artery with particular reference to its relationship with the frontal recess.

  2. Evaluation of natural- and forced-draft staging air systems for nitric oxide reduction in refinery process heaters. Volume 2. Data supplement. Final report October 1982-February 1984

    Energy Technology Data Exchange (ETDEWEB)

    Benson, R.C.; Frohoff, R.A.; Markee, J.A.

    1984-08-01

    The two-volume report gives results of pilot-scale tests to evaluate combustion modifications for emission reduction and efficiency enhancement on petroleum process heaters. Objectives were to determine nitric oxide (NO) emission reductions, thermal efficiency changes, long-term performance, and cost of both natural- and forced-draft staged-combustion-air modifications. Forced-draft-staged-combustion-air modifications had been shown to be the most promising combustion modification in previous pilot-scale tests. The test unit was a vertical, cylindrical, natural-draft crude heater, and the test fuels were natural gas, refinery gas, and a combination of No. 6 oil and refinery gas.

  3. Evaluation of influence of the locality, the vintage year, wine variety and fermentation process on volume of cooper and lead in wine

    Directory of Open Access Journals (Sweden)

    Jaroslav Jedlička

    2014-11-01

    Full Text Available We have focused on the influence evaluation of the locality, the vintage year and fermentation process on the volume of copper and lead into grape must and wine. First of all copper and lead volume was assessed into fresh grape musts. Subsequently the musts were fermented. During the wines analyses we found great decrease of copper by the fermentation process. Assessed Cu2+ values vary from 0.07 to 0.2 mg.L-1 and represent a decrease of the original copper volume from 90 to 97%. On the copper content into grape has probably the significant influence also the precipitation amount, which falling in the second part of the vegetation half a year. Total rainfall in the period before the grape harvesting (the months of August - September was for the first year 153 mm and for second year 137,5 mm. During both observed vintage years it was concerning to the above average values. Copper is not possible to eliminate totally in the protection of the vine against fungal diseases, because against it does not come into existence resistance into a pathogen. For resolution of this problem it is suitable to combine the copper and organic products. Fermentation affect as a biological filter and influence also lead volume. Into analysed wines we found the decrease of the lead volume from 25 to 94%. Maximal assessed Pb2+ value into wine was 0.09 mg.L-1. The linear relationship between lead and copper into grape must in relationship to the lead and copper into wine was not statistically demonstrated. We found the statistically significant relationship in lead content into grape must by the influence of the vintage year, which as we supposed, it was connected with the atmospheric precipitation quantity and distribution during the vegetation. On the base of the assessed results of the lead and copper volume into wine, we state that by using of the faultless material and appropriate technological equipment during the wine production, it is possible to eliminate almost

  4. Evaluation of Low versus High Volume per Minute Displacement CO2 Methods of Euthanasia in the Induction and Duration of Panic-Associated Behavior and Physiology

    Directory of Open Access Journals (Sweden)

    Debra L. Hickman

    2016-08-01

    Full Text Available Current recommendations for the use of CO 2 as a euthanasia agent for rats require the use of gradual fill protocols (such as 10% to 30% volume displacement per minute in order to render the animal insensible prior to exposure to levels of CO 2 that are associated with pain. However, exposing rats to CO 2 , concentrations as low as 7% CO 2 are reported to cause distress and 10%–20% CO 2 induces panic-associated behavior and physiology, but loss of consciousness does not occur until CO 2 concentrations are at least 40%. This suggests that the use of the currently recommended low flow volume per minute displacement rates create a situation where rats are exposed to concentrations of CO 2 that induce anxiety, panic, and distress for prolonged periods of time. This study first characterized the response of male rats exposed to normoxic 20% CO 2 for a prolonged period of time as compared to room air controls. It demonstrated that rats exposed to this experimental condition displayed clinical signs consistent with significantly increased panic-associated behavior and physiology during CO 2 exposure. When atmospheric air was then again delivered, there was a robust increase in respiration rate that coincided with rats moving to the air intake. The rats exposed to CO 2 also displayed behaviors consistent with increased anxiety in the behavioral testing that followed the exposure. Next, this study assessed the behavioral and physiologic responses of rats that were euthanized with 100% CO 2 infused at 10%, 30%, or 100% volume per minute displacement rates. Analysis of the concentrations of CO 2 and oxygen in the euthanasia chamber and the behavioral responses of the rats suggest that the use of the very low flow volume per minute displacement rate (10% may prolong the duration of panicogenic ranges of ambient CO 2 , while the use of the higher flow volume per minute displacement rate (100% increases agitation. Therefore, of the volume displacement per

  5. Utilisation, contents and costs of prenatal care under a rural health insurance (New Co-operative Medical System in rural China: lessons from implementation

    Directory of Open Access Journals (Sweden)

    Tang Xiaojun

    2010-11-01

    Full Text Available Abstract Background In China, the New Co-operative Medical System (NCMS, a rural health insurance system, has expanded nationwide since 2003. This study aims to describe prenatal care use, content and costs of care in one county where prenatal care is included in the NCMS and two counties where it is not. It also explores the perceptions of stakeholders of the prenatal care benefit package in order to understand the strengths and weaknesses of the approach in the context of rural China and to draw lessons from early implementation. Methods This study is based on the data from a cross-sectional survey and a qualitative investigation conducted in 2009. A survey recruited women giving birth in 2008, including 544 women in RC County (which covered prenatal care and 619, and 1071 in other two counties (which did not. The qualitative investigation in RC included focus group discussions with women giving birth before or after 2007, individual interviews with local policy makers and health managers, NCMS managers and obstetric doctors in township hospitals. Results There were no significant differences in prenatal care use between RC County (which covered prenatal care and other two counties (which did not: over 70% of women started prenatal visits early and over 60% had five or more visits. In the three counties: a small proportion of women received the number of haemoglobin and urine tests recommended by the national guideline; 90% of women received more ultrasound tests than recommended; and the out-of-pocket expenditure for prenatal care consumed a high proportion of women's annual income in the low income group. In RC: only 20% of NCMS members claimed the reimbursement; the qualitative study found that the reimbursement for prenatal care was not well understood by women and had little influence on women's decisions to make prenatal visits; and several women indicated that doctors suggested them taking more expensive tests. Conclusions Whether or

  6. Evaluating the influence of half-life, milk:plasma partition coefficient, and volume of distribution on lactational exposure to chemicals in children.

    Science.gov (United States)

    Verner, Marc-André; Plouffe, Laurence; Kieskamp, Kyra K; Rodríguez-Leal, Inés; Marchitti, Satori A

    2017-05-01

    Women are exposed to multiple environmental chemicals, many of which are known to transfer to breast milk during lactation. However, little is known about the influence of the different chemical-specific pharmacokinetic parameters on children's lactational dose. Our objective was to develop a generic pharmacokinetic model and subsequently quantify the influence of three chemical-specific parameters (biological half-life, milk:plasma partition coefficient, and volume of distribution) on lactational exposure to chemicals and resulting plasma levels in children. We developed a two-compartment pharmacokinetic model to simulate lifetime maternal exposure, placental transfer, and lactational exposure to the child. We performed 10,000 Monte Carlo simulations where half-life, milk:plasma partition coefficient, and volume of distribution were varied. Children's dose and plasma levels were compared to their mother's by calculating child:mother dose ratios and plasma level ratios. We then evaluated the association between the three chemical-specific pharmacokinetic parameters and child:mother dose and level ratios through linear regression and decision trees. Our analyses revealed that half-life was the most influential parameter on children's lactational dose and plasma concentrations, followed by milk:plasma partition coefficient and volume of distribution. In bivariate regression analyses, half-life explained 72% of child:mother dose ratios and 53% of child:mother level ratios. Decision trees aiming to identify chemicals with high potential for lactational exposure (ratio>1) had an accuracy of 89% for child:mother dose ratios and 84% for child:mother level ratios. Our study showed the relative importance of half-life, milk:plasma partition coefficient, and volume of distribution on children's lactational exposure. Developed equations and decision trees will enable the rapid identification of chemicals with a high potential for lactational exposure. Copyright © 2017

  7. The Effects of Head Start Health Services: Report of the Head Start Health Evaluation. Volume I and II.

    Science.gov (United States)

    Fosburg, Linda B.; And Others

    In 1977, a longitudinal study was initiated to assess the effectiveness of health services provided by Head Start. The study provided for 10 domains: pediatric health examinations, health history recordings, dental evaluation, anthropometric assessment, diet and nutrition assessment, and hematology evaluations, as well as for developmental,…

  8. Reconsidering Ampere’s Double Layer Representation for Magnetic Field, Evaluation in a NDE Dection of a zero volume crack

    Directory of Open Access Journals (Sweden)

    M. Poloujadoff

    2014-04-01

    Full Text Available The paper has two different objectives. The first one is to  show that Ampere’s double layer method, which is equivalent  to one of the Maxwell equations, leads to the integration of a  simple closed form expression, thus avoiding the need to solve  complicated partial differential equations. The second aim is  to study the case of a zero volume defect in a NDE problem by  a perturbation method and the introduction of a double layer.  The combination of these two techniques leads to a very fast  solution of the problem. A practical example including

  9. Experimental Evaluation of the Applicability of Capacitive and Optical Measurement Methods for the Determination of Liquid Hydrogen Volume Flow

    Directory of Open Access Journals (Sweden)

    Gert HOLLER

    2009-08-01

    Full Text Available This paper presents a capacitive and a vision-based method for measuring the velocity of cryogenic hydrogen flows. The capacitive sensing principle exploits the spatial frequency signature of perturbations moving through a multi-electrode structure. This setup increases the sensitivity to dielectric permittivity variations compared to a simple two-electrode structure while preserving the ability to detect small perturbations. The vision-based method relies on a high-speed camera system that monitors the liquid hydrogen flow through an optical window yielding the flow velocity by cross-correlating subsequent images of the flow. Although a comprehensive analysis of the obtainable measurement uncertainty was not performed yet, current measurement results show the applicability of both principles for the non-invasive measurement of the volume flow of cryogenic fuels inside conveyor pipes.

  10. Physical Selectivity of Molecularly Imprinted polymers evaluated through free volume size distributions derived from Positron Lifetime Spectroscopy

    Science.gov (United States)

    Pasang, T.; Ranganathaiah, C.

    2015-06-01

    The technique of imprinting molecules of various sizes in a stable structure of polymer matrix has derived multitudes of applications. Once the template molecule is extracted from the polymer matrix, it leaves behind a cavity which is physically (size and shape) and chemically (functional binding site) compatible to the particular template molecule. Positron Annihilation Lifetime Spectroscopy (PALS) is a well known technique to measure cavity sizes precisely in the nanoscale and is not being used in the field of MIPs effectively. This method is capable of measuring nanopores and hence suitable to understand the physical selectivity of the MIPs better. With this idea in mind, we have prepared molecular imprinted polymers (MIPs) with methacrylicacid (MAA) as monomer and EGDMA as cross linker in different molar ratio for three different size template molecules, viz. 4-Chlorophenol (4CP)(2.29 Å), 2-Nephthol (2NP) (3.36 Å) and Phenolphthalein (PP) (4.47Å). FTIR and the dye chemical reactions are used to confirm the complete extraction of the template molecules from the polymer matrix. The free volume size and its distribution have been derived from the measured o-Ps lifetime spectra. Based on the free volume distribution analysis, the percentage of functional cavities for the three template molecules are determined. Percentage of functional binding cavities for 4-CP molecules has been found out to be 70.2% and the rest are native cavities. Similarly for 2NP it is 81.5% and nearly 100% for PP. Therefore, PALS method proves to be very precise and accurate for determining the physical selectivity of MIPs.

  11. Fluorescent dye imaging of the volume sampled by single well forced-gradient tracer tests evaluated in a laboratory-scale aquifer physical model.

    Science.gov (United States)

    Barns, Gareth L; Wilson, Ryan D; Thornton, Steven F

    2012-02-01

    This study presents a new method to visualise forced-gradient tracer tests in 2-D using a laboratory-scale aquifer physical model. Experiments were designed to investigate the volume of aquifer sampled in vertical dipole flow tracer tests (DFTT) and push-pull tests (PPT), using a miniature monitoring well and straddle packer arrangement equipped with solute injection and recovery chambers. These tests have previously been used to estimate bulk aquifer hydraulic and transport properties for the evaluation of natural attenuation and other remediation approaches. Experiments were performed in a silica glass bead-filled box, using a fluorescent tracer (fluorescein) to deduce conservative solute transport paths. Digital images of fluorescein transport were captured under ultraviolet light and processed to analyse tracer plume geometry and obtain point-concentration breakthrough histories. Inorganic anion mixtures were also used to obtain conventional tracer breakthrough histories. Concentration data from the conservative tracer breakthrough curves was compared with the digital images and a well characterised numerical model. The results show that the peak tracer breakthrough response in dipole flow tracer tests samples a zone of aquifer close to the well screen, while the sampling volume of push-pull tests is limited by the length of the straddle packers used. The effective sampling volume of these single well forced-gradient tests in isotropic conditions can be estimated with simple equations. The experimental approach offers the opportunity to evaluate under controlled conditions the theoretical basis, design and performance of DFTTs and PPTs in porous media in relation to measured flow and transport properties. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Evaluated kinetic and photochemical data for atmospheric chemistry: Volume IV – gas phase reactions of organic halogen species

    Directory of Open Access Journals (Sweden)

    R. Atkinson

    2008-08-01

    Full Text Available This article, the fourth in the series, presents kinetic and photochemical data sheets evaluated by the IUPAC Subcommittee on Gas Kinetic Data Evaluation for Atmospheric Chemistry. It covers the gas phase and photochemical reactions of organic halogen species, which were last published in 1997, and were updated on the IUPAC website in 2006/07. The article consists of a summary sheet, containing the recommended kinetic parameters for the evaluated reactions, and four appendices containing the data sheets, which provide information upon which the recommendations are made.

  13. Evaluated kinetic and photochemical data for atmospheric chemistry: Volume I - gas phase reactions of Ox, HOx, NOx and SOx species

    Directory of Open Access Journals (Sweden)

    R. Atkinson

    2004-01-01

    Full Text Available This article, the first in the series, presents kinetic and photochemical data evaluated by the IUPAC Subcommittee on GasKinetic Data Evaluation for Atmospheric Chemistry. It covers the gas phase and photochemical reactions of Ox, HOx, NOx and SOx species, which were last published in 1997, and were updated on the IUPAC website in late 2001. The article consists of a summary sheet, containing the recommended kinetic parameters for the evaluated reactions, and five appendices containing the data sheets, which provide information upon which the recommendations are made.

  14. Evaluated kinetic and photochemical data for atmospheric chemistry: Volume II – gas phase reactions of organic species

    Directory of Open Access Journals (Sweden)

    R. Atkinson

    2006-01-01

    Full Text Available This article, the second in the series, presents kinetic and photochemical data evaluated by the IUPAC Subcommittee on Gas Kinetic Data Evaluation for Atmospheric Chemistry. It covers the gas phase and photochemical reactions of Organic species, which were last published in 1999, and were updated on the IUPAC website in late 2002, and subsequently during the preparation of this article. The article consists of a summary table of the recommended rate coefficients, containing the recommended kinetic parameters for the evaluated reactions, and eight appendices containing the data sheets, which provide information upon which the recommendations are made.

  15. Criteria for the development and use of the methodology for environmentally-acceptable fossil energy site evaluation and selection. Volume 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Eckstein, L.; Northrop, G.; Scott, R.

    1980-02-01

    This report serves as a companion document to the report, Volume 1: Environmentally-Acceptable Fossil Energy Site Evaluation and Selection: Methodology and Users Guide, in which a methodology was developed which allows the siting of fossil fuel conversion facilities in areas with the least environmental impact. The methodology, known as SELECS (Site Evaluation for Energy Conversion Systems) does not replace a site specific environmental assessment, or an environmental impact statement (EIS), but does enhance the value of an EIS by thinning down the number of options to a manageable level, by doing this in an objective, open and selective manner, and by providing preliminary assessment and procedures which can be utilized during the research and writing of the actual impact statement.

  16. Excess Molar Volumes and Partial Molar Volumes of Binary Systems ...

    African Journals Online (AJOL)

    NJD

    Excess molar volumes have been evaluated from density measurements over the entire composition range for binary systems of an ionic liquid ... was used to fit the excess molar volume data and the partial molar volumes were determined from the Redlich-Kister coefficients. ... ture below the boiling point of water. Most of ...

  17. Proceedings of the International Conference on Teaching Statistics (1st, University of Sheffield, England, August 9-13, 1982). Volume II.

    Science.gov (United States)

    Grey, D. R., Ed.; And Others

    The second volume of these conference proceedings includes 35 papers presented under seven topic headings. The topic headings are: (1) education and training in statistics in developing countries; (2) co-operation between academic and practicing statisticians; (3) teaching survey sampling; (4) teaching design and analysis of experiments; (5)…

  18. Risk management study for the retired Hanford Site facilities: Qualitative risk evaluation for the retired Hanford Site facilities. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Coles, G.A.; Shultz, M.V.; Taylor, W.E.

    1993-09-01

    This document provides a risk evaluation of the 100 and 200 Area retired, surplus facilities on the Hanford Site. Also included are the related data that were compiled by the risk evaluation team during investigations performed on the facilities. Results are the product of a major effort performed in fiscal year 1993 to produce qualitative information that characterizes certain risks associated with these facilities. The retired facilities investigated for this evaluation are located in the 100 and 200 Areas of the 1,450-km{sup 2} (570-mi{sup 2}) Hanford Site. The Hanford Site is a semiarid tract of land in southeastern Washington State. The nearest population center is Richland, Washington, (population 32,000) 30-km (20 mi) southeast of the 200 Area. During walkdown investigations of these facilities, data on real and potential hazards that threatened human health or safety or created potential environmental release issues were identified by the risk evaluation team. Using these findings, the team categorized the identified hazards by facility and evaluated the risk associated with each hazard. The factors contributing to each risk, and the consequence and likelihood of harm associated with each hazard also are included in this evaluation.

  19. The Streambank Erosion Control Evaluation and Demonstration Act of 1974, Section 32, Public Law 93-251. Appendix H. Evaluation of Existing Projects. Volume 1.

    Science.gov (United States)

    1981-12-01

    to 7 Red River, Fausse , Louisiana......................................... H-4-1 to 6 Red River, Perot, Louisiana...States were selected for limited observation, monitoring, and evaluation using previous field observations and data and information acquired during the...projects evaluated. A detailed report on each of these projects is provided in this appendix; a summary of information on these projects is given in Exhibit

  20. Protocol to the 1994 Co-operation Agreement between The Government of the Islamic Republic of Pakistan and CERN concerning a Special Contribution by Pakistan towards the Construction of the LHC

    CERN Document Server

    2003-01-01

    CERN signed a Co-operation Agreement with the Government of Pakistan in 1994, which was followed in 1997 by a Protocol signed with the Pakistan Atomic Energy Commission (PAEC) concerning CMS magnet supports. CERN and PAEC then signed in 1998 a Memorandum of Understanding for collaboration in the construction of the CMS detector. The participation by Pakistani scientists and engineers in the CERN programme is channelled through the National Centre of Physics (NCP) established at the Quaid-i-Azzam University in Islamabad, under the terms of a 1999 Protocol to the 1994 Co-operation Agreement. The engineering and detector construction work performed under these Agreements has been of high quality, and the Pakistani participation is valued highly by the CMS collaboration. In continuation of this co-operation, Pakistan, represented by PAEC as funding agency, has now proposed to make in-kind contributions to the LHC Project of a value of up to ten million US dollars. Under the proposed scheme, CERN shall pay 50% of ...