Are Differences Between Partners Always Detrimental? The Moderating Role of Future Connectedness

Directory of Open Access Journals (Sweden)

Simon Andrew Moss

2014-12-01

Full Text Available Whether perceived differences between romantic partners compromises or enhances relationships may depend on the characteristics of individuals. This study explores the possibility that differences in capabilities but not motives enhance relationship satisfaction—but only when the individuals feel connected to their future identity. In particular, when individuals feel connected to their future identity, their primary motivation is to accrue capabilities and resources that could be useful in subsequent decades. They will thus seek partners with capabilities they have yet to acquire because, consistent with self-expansion theory, they tend to perceive these abilities as part of their own self-concept. To test this premise, 152 individuals rated the motives and capabilities of both themselves and their partners and also answered questions that gauge their relationship satisfaction and connectedness to their future identity. Perceived differences in motives and capabilities were inversely associated with relationship satisfaction. However, when participants felt connected to their future identity, the inverse association between differences in capabilities and relationship satisfaction diminished. Accordingly, if individuals perceive their lives as stable, they can embrace some differences between themselves and their partner.

Are Differences Between Partners Always Detrimental? The Moderating Role of Future Connectedness

OpenAIRE

Simon Andrew Moss; Jasmine Dolan

2014-01-01

Whether perceived differences between romantic partners compromises or enhances relationships may depend on the characteristics of individuals. This study explores the possibility that differences in capabilities but not motives enhance relationship satisfaction—but only when the individuals feel connected to their future identity. In particular, when individuals feel connected to their future identity, their primary motivation is to accrue capabilities and resources that could be useful in s...

Hierarchy is Detrimental for Human Cooperation.

Science.gov (United States)

Cronin, Katherine A; Acheson, Daniel J; Hernández, Penélope; Sánchez, Angel

2015-12-22

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species.

Hierarchy is Detrimental for Human Cooperation

Science.gov (United States)

Cronin, Katherine A.; Acheson, Daniel J.; Hernández, Penélope; Sánchez, Angel

2015-01-01

Studies of animal behavior consistently demonstrate that the social environment impacts cooperation, yet the effect of social dynamics has been largely excluded from studies of human cooperation. Here, we introduce a novel approach inspired by nonhuman primate research to address how social hierarchies impact human cooperation. Participants competed to earn hierarchy positions and then could cooperate with another individual in the hierarchy by investing in a common effort. Cooperation was achieved if the combined investments exceeded a threshold, and the higher ranked individual distributed the spoils unless control was contested by the partner. Compared to a condition lacking hierarchy, cooperation declined in the presence of a hierarchy due to a decrease in investment by lower ranked individuals. Furthermore, hierarchy was detrimental to cooperation regardless of whether it was earned or arbitrary. These findings mirror results from nonhuman primates and demonstrate that hierarchies are detrimental to cooperation. However, these results deviate from nonhuman primate findings by demonstrating that human behavior is responsive to changing hierarchical structures and suggests partnership dynamics that may improve cooperation. This work introduces a controlled way to investigate the social influences on human behavior, and demonstrates the evolutionary continuity of human behavior with other primate species. PMID:26692287

Radiation induced cancer risk, detriment and radiation protection

International Nuclear Information System (INIS)

Sinclair, W.K.

1992-01-01

Recommendations on radiation protection limits for workers and for the public depend mainly on the total health detriment estimated to be the result of low dose ionizing radiation exposure. This detriment includes the probability of a fatal cancer, an allowance for the morbidity due to non-fatal cancer and the probability of severe hereditary effects in succeeding generations. In a population of all ages, special effects on the fetus particularly the risk of mental retardation at defined gestational ages, should also be included. Among these components of detriment after low doses, the risk of fatal cancer is the largest and most important. The estimates of fatal cancer risk used by ICRP in the 1990 recommendations were derived almost exclusively from the study of the Japanese survivors of the atomic bombs of 1945. How good are these estimates? Uncertainties associated with them, apart from those due to limitations in epidemiological observation and dosimetry, are principally those due to projection forward in time and extrapolation from high dose and dose rate to low dose and dose rate, each of which could after the estimate by a factor of 2 or so. Recent estimates of risk of cancer derived directly from low dose studies are specific only within very broad ranges of risk. Nevertheless, such studies are important as confirmation or otherwise of the estimates derived from the atomic bomb survivors. Recent U.S. British and Russian studies are examined in this light. (author)

Valuing the radiation detriment of occupational exposure

International Nuclear Information System (INIS)

Robb, J.D.; Crick, M.J.

1989-01-01

The implications of changes in the radiation risk estimates on the valuation of radiation detriment for use in cost-benefit analysis are being considered at the National Radiological Protection Board. This paper discusses the pertinent factors that are currently being considered for further investigation. An example of relevance to occupational exposure is detailed. (author)

Disuse exaggerates the detrimental effects of alcohol on cortical bone

Science.gov (United States)

Hefferan, Theresa E.; Kennedy, Angela M.; Evans, Glenda L.; Turner, Russell T.

2003-01-01

BACKGROUND: Alcohol abuse is associated with an increased risk for osteoporosis. However, comorbidity factors may play an important role in the pathogenesis of alcohol-related bone fractures. Suboptimal mechanical loading of the skeleton, an established risk factor for bone loss, may occur in some alcohol abusers due to reduced physical activity, muscle atrophy, or both. The effect of alcohol consumption and reduced physical activity on bone metabolism has not been well studied. The purpose of this study was to determine whether mechanical disuse alters bone metabolism in a rat model for chronic alcohol abuse. METHODS: Alcohol was administered in the diet (35% caloric intake) of 6-month-old male rats for 4 weeks. Rats were hindlimb-unloaded the final 2 weeks of the experiment to prevent dynamic weight bearing. Afterward, cortical bone histomorphometry was evaluated at the tibia-fibula synostosis. RESULTS: At the periosteal surface of the tibial diaphysis, alcohol and hindlimb unloading independently decreased the mineralizing perimeter, mineral apposition rate, and bone formation rate. In addition, alcohol, but not hindlimb unloading, increased endocortical bone resorption. The respective detrimental effects of alcohol and hindlimb unloading to inhibit bone formation were additive; there was no interaction between the two variables. CONCLUSIONS: Reduced weight bearing accentuates the detrimental effects of alcohol on cortical bone in adult male rats by further inhibiting bone formation. This finding suggests that reduced physical activity may be a comorbidity factor for osteoporosis in alcohol abusers.

E-cigarettes also contain detrimental chemicals

DEFF Research Database (Denmark)

Tøttenborg, Sandra Søgaard; Holm, Astrid Ledgaard; Wibholm, Niels Christoffer

2014-01-01

This article reviews studies dealing with the content of electronic (e-) cigarettes. Based on measurements of the e-juice, the inhaled and the exhaled vapour, it is sound to assume that smoking e-cigarettes might have much less detrimental health effects than smoking conventional cigarettes....... However, propylene glycol and glycerine are abundant in e-cigarettes and although they are generally perceived as relatively harmless, the long-term effects of heavy exposure to these substances are unknown....

Nanostructured magnesium has fewer detrimental effects on osteoblast function

Directory of Open Access Journals (Sweden)

Weng L

2013-05-01

Full Text Available Lucy Weng, Thomas J Webster School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USA Abstract: Efforts have been made recently to implement nanoscale surface features on magnesium, a biodegradable metal, to increase bone formation. Compared with normal magnesium, nanostructured magnesium has unique characteristics, including increased grain boundary properties, surface to volume ratio, surface roughness, and surface energy, which may influence the initial adsorption of proteins known to promote the function of osteoblasts (bone-forming cells. Previous studies have shown that one way to increase nanosurface roughness on magnesium is to soak the metal in NaOH. However, it has not been determined if degradation of magnesium is altered by creating nanoscale features on its surface to influence osteoblast density. The aim of the present in vitro study was to determine the influence of degradation of nanostructured magnesium, created by soaking in NaOH, on osteoblast density. Our results showed a less detrimental effect of magnesium degradation on osteoblast density when magnesium was treated with NaOH to create nanoscale surface features. The detrimental degradation products of magnesium are of significant concern when considering use of magnesium as an orthopedic implant material, and this study identified a surface treatment, ie, soaking in NaOH to create nanoscale features for magnesium that can improve its use in numerous orthopedic applications. Keywords: nanostructured magnesium, degradation, detrimental effects, osteoblasts

Detrimental role of hydrogen on the corrosion rate of zirconium alloys

International Nuclear Information System (INIS)

Blat, M.; Noel, D.

1996-01-01

Recent studies have suggested that hydride precipitation at the metal/oxide interface could play a detrimental role on the waterside corrosion rate. Nevertheless, the mechanism of that detrimental role is not completely understood, and two hypotheses were investigated to understand the mechanism that controls the role of the hydrides. The first hypothesis is based on a mechanical effect: the hydrides precipitate at the metal/oxide interface and destroy the physical integrity of the barrier oxide layer. The second hypothesis is a modification of the transport properties of the oxide grown on the hydrided metal. The detrimental role of hydrides on the corrosion rate was studied by charging unirradiated Zircaloy-4 cladding material with hydrogen to a level higher than the limit of solubility at 400 C. Both gaseous and cathodic charging techniques were used. Static corrosion tests were carried out in autoclave with steam at 400 C on an as-received and hydrided sample. The detrimental role of hydrides is confirmed from the post-transition corrosion rate, and that effect is more significant for high cathodic charging. The results of the metallurgical examinations are discussed to provide an understanding of the mechanism. No relationship between hydrides, physical defects in the oxide, and local corrosion rate enhancement was found. Therefore, the results do not support the hypothesis of a mechanical effect at the scale of the performed examinations, but more detailed work is required to confirm this

Quantifying the detrimental impacts of land-use and management change on European forest bird populations.

Directory of Open Access Journals (Sweden)

Amy S I Wade

Full Text Available The ecological impacts of changing forest management practices in Europe are poorly understood despite European forests being highly managed. Furthermore, the effects of potential drivers of forest biodiversity decline are rarely considered in concert, thus limiting effective conservation or sustainable forest management. We present a trait-based framework that we use to assess the detrimental impact of multiple land-use and management changes in forests on bird populations across Europe. Major changes to forest habitats occurring in recent decades, and their impact on resource availability for birds were identified. Risk associated with these changes for 52 species of forest birds, defined as the proportion of each species' key resources detrimentally affected through changes in abundance and/or availability, was quantified and compared to their pan-European population growth rates between 1980 and 2009. Relationships between risk and population growth were found to be significantly negative, indicating that resource loss in European forests is an important driver of decline for both resident and migrant birds. Our results demonstrate that coarse quantification of resource use and ecological change can be valuable in understanding causes of biodiversity decline, and thus in informing conservation strategy and policy. Such an approach has good potential to be extended for predictive use in assessing the impact of possible future changes to forest management and to develop more precise indicators of forest health.

Improved Cholinergic Transmission is Detrimental to Behavioural Plasticity in Honeybees (Apis mellifera

Directory of Open Access Journals (Sweden)

Shao-Wu Zhang

2012-10-01

Full Text Available Unravelling the role of neuromessenger processes in learning and memory has long interested researchers. We investigated the effects of an acetylcholinesterase blocker, Methyl Parathion (MeP, on honeybee learning. We used visual and olfactory tasks to test whether MeP had a detrimental effect on the acquisition of new knowledge when this new knowledge contradicts previously acquired one. Our results indicate that treatment with MeP prior to conditioning was significantly detrimental to the acquisition of incongruous (but not irrelevant or congruous new knowledge due to improved recall. The neurobiological and ecotoxicological consequences of these results are discussed.

The use of total detriment in radiation protection and its potential extension to other hazards

International Nuclear Information System (INIS)

Johnson, J.R.; Stansbury, P.S.; Selby, J.M.

1991-10-01

Before publication of the 1977 recommendations of the International Commission on Radiological Protection (ICRP), radiation protection standards were based on dose limits to single organs. These dose limits were only loosely linked to the expected effects in the first two generations from gonadal doses and to the risk of fatal cancer from doses to specific organs. In 1977, the ICRP recommended the use of the ''effective dose equivalent (EDE),'' which is a method of summing the doses (weighted with relative risk coefficients) to all organs and tissues, and recommended an annual limit for EDE. Since the 1977 recommendations were published, a ''total risk'' or total detriment approach has been extended to include nonfatal cancers and genetic effects for all subsequent generations, i.e., the total health detriment from low doses of ionizing radiation. This paper discusses the development of this total health detriment from ionizing radiation exposures, and explores potential methods for using it with other hazards (such as exposures to other physical agents, hazardous chemicals, and fatal and nonfatal accidents) in calculating the total detriment to a worker

Assessment of public awareness of the detrimental effects of ionizing radiation in Kontagora, Niger State, Nigeria

International Nuclear Information System (INIS)

Temaugee, S.T.; Daniel, T.A.; Oladejo, K.O.; Daniel, S.

2014-01-01

This study investigated the level of public awareness of detrimental effects of ionizing radiation in Nigeria, a case study of Federal College of Education Kontagora Niger State. A total of thirty-five (35) lecturers and seventy-five (75) students were randomly selected from the five schools in the College. The instrument used for data collection was a questionnaire. Data obtained from the questionnaire was analysed using simple percentages. The result of the study revealed that 10 (28.6%) out of 35 lecturers and 32 (42.7%) out of 75 students of the sampled population were totally unaware of ionization radiation and its health detriments. Moreover, the remaining percentage of both lecturers and students had limited knowledge about ionizing radiation and its detrimental effects to humans. The research also shows that a significant percentage of both lecturers and students claimed that the topic 'Ionizing radiations and their health detriments' is not relevant to their field of academic inclination. Based on the findings of the research, it was therefore recommended that the government, Nigeria Nuclear Regulatory Agency (NNRA), physicists and concerned individuals should enlighten the general public on ionizing radiations, its health detriment and safety measures through seminars and the mass media.

Survey of the ICRP 103 detriment-model; Untersuchung und Bewertung des Detrimentbegriffs im Strahlenschutz

Energy Technology Data Exchange (ETDEWEB)

Emami, S.; Buermeyer, J.; Spruck, K.; Breckow, J. [Technische Hochschule Mittelhessen (THM), Giessen (Germany). Inst. fuer Medizinische Physik und Strahlenschutz (IMPS)

2016-07-01

The detriment of ICRP 103 is roughly defined as the product of the (organ specific) risk coefficient and the ''damage'' that may be associated with a (organ specific) cancer or hereditary effect, respectively. This is to indicate a weighted risk according to the radiation sensitivity of the different organs and the severity of damage that may possibly arise. Whereas the risk coefficients refer to radiation exposure parameters, the scale or degree of damage is independent of these parameters. The radiation independent parameters are the lethality, the loss of quality of life and the reduced life expectancy, which are considered as quantities associated with the severity of disease or damage, respectively. These parameters may change gradually, on the one hand possibly due to an increase of cancer becoming a common disease within the population. On the other hand, possibly to a decrease of cancer due to the progress in medical diagnostics and treatments that allow patients to survive or at least maintain a higher life quality standard. The damage and therefore the detriment appears to be mostly affected by the lethality. The lethality is the quotient of mortality to incidence. The investigation of the detriment presented in this paper focuses on the influence of the lethality on the detriment from 1980-2012 in Germany and USA.

Evaluation of radiological detriment from negative radiological examinations

International Nuclear Information System (INIS)

Frometa Suarez, I.; Jerez Vergueria, S.F.

1997-01-01

The individul doses of radiation due to diagnostic radiology are usually low, though their contribution to the collective dose is very important given the large numbers of people exposed to these. This paper presents an analysis of the number of negative radiologiacl examinations in a major Cuban Hospital, and their contribution to the collective dose, and radiation organ and tissue, effective (expressed as severe hereditary effect and the occurrence of fatal and non fatal cancers) are all evaluated. The negative findings constitute 41 % of all examinations. The total contribution of negative examinations to the collective dose is very important given the large numbers of people exposed to these. This papaer presents an analysis of the number of negative radiological examinations in major Cuban Hospital, and their contribution to the collective dose of radiation. The absorbed dose by irradiation organ and tissue, effective dose equivalent, collective dose, and radiation risk (expressed as severe herditary effect and the occureence of fatal and non fatal cancers) are all evaluated. The negative findings constitute 41% of all examinations. The total contribution of negative examinations. The total contribution of negative examinations to the collective dose are found to make up 52.9 %: 11.35 Sv-man in the studied population

Nanostructured magnesium has fewer detrimental effects on osteoblast function

Science.gov (United States)

Weng, Lucy; Webster, Thomas J

2013-01-01

Efforts have been made recently to implement nanoscale surface features on magnesium, a biodegradable metal, to increase bone formation. Compared with normal magnesium, nanostructured magnesium has unique characteristics, including increased grain boundary properties, surface to volume ratio, surface roughness, and surface energy, which may influence the initial adsorption of proteins known to promote the function of osteoblasts (bone-forming cells). Previous studies have shown that one way to increase nanosurface roughness on magnesium is to soak the metal in NaOH. However, it has not been determined if degradation of magnesium is altered by creating nanoscale features on its surface to influence osteoblast density. The aim of the present in vitro study was to determine the influence of degradation of nanostructured magnesium, created by soaking in NaOH, on osteoblast density. Our results showed a less detrimental effect of magnesium degradation on osteoblast density when magnesium was treated with NaOH to create nanoscale surface features. The detrimental degradation products of magnesium are of significant concern when considering use of magnesium as an orthopedic implant material, and this study identified a surface treatment, ie, soaking in NaOH to create nanoscale features for magnesium that can improve its use in numerous orthopedic applications. PMID:23674891

Nanostructured magnesium has fewer detrimental effects on osteoblast function.

Science.gov (United States)

Weng, Lucy; Webster, Thomas J

2013-01-01

Efforts have been made recently to implement nanoscale surface features on magnesium, a biodegradable metal, to increase bone formation. Compared with normal magnesium, nanostructured magnesium has unique characteristics, including increased grain boundary properties, surface to volume ratio, surface roughness, and surface energy, which may influence the initial adsorption of proteins known to promote the function of osteoblasts (bone-forming cells). Previous studies have shown that one way to increase nanosurface roughness on magnesium is to soak the metal in NaOH. However, it has not been determined if degradation of magnesium is altered by creating nanoscale features on its surface to influence osteoblast density. The aim of the present in vitro study was to determine the influence of degradation of nanostructured magnesium, created by soaking in NaOH, on osteoblast density. Our results showed a less detrimental effect of magnesium degradation on osteoblast density when magnesium was treated with NaOH to create nanoscale surface features. The detrimental degradation products of magnesium are of significant concern when considering use of magnesium as an orthopedic implant material, and this study identified a surface treatment, ie, soaking in NaOH to create nanoscale features for magnesium that can improve its use in numerous orthopedic applications.

Climate change impact on future ocean acidification

International Nuclear Information System (INIS)

McNeil, Ben

2007-01-01

Full text: Elevated atmospheric C02 levels and associated uptake by the ocean is changing its carbon chemistry, leading to an acidification. The implications of future ocean acidification on the marine ecosystem are unclear but seemingly detrimental particularly to those organisms and phytoplankton that secrete calcium carbonate (like corals). Here we present new results from the Australian CSIRO General Circulation Model that predicts the changing nature of oceanic carbon chemistry in response to future climate change feedbacks (circulation, temperature and biological). We will discuss the implications of future ocean acidification and the potential implications on Australia's marine ecosystems

Economic discounting in the assessment of detriment due to biosphere contamination by nuclear power enterprises

International Nuclear Information System (INIS)

Demin, V.F.; Ermakova, E.I.; Shevelev, Ya.V.

1983-01-01

In addition to existing concepts of total and partial expected collective doze, discounting expected collective dose Ssup(c)d is suggested to be introduced as the basis for estimation of the detriment due to biosphere contamination by wastes from enterprises of nuclear power. Unlike the total expected dose. the Ssup(c)d value is evaluated taking into account the discounting function known in economy. Calculation Ssup(c)d values for different stages of nuclear fuel cycle with a light-water reactor are given. For the cycle on the whole, the Ssup(c)d value is approximately by 2 or 3 orders of masnitude lower than the corresponding total expected collective dose

Elevated homocysteine by levodopa is detrimental to neurogenesis in parkinsonian model.

Directory of Open Access Journals (Sweden)

Jin Young Shin

Full Text Available BACKGROUND: Modulation of neurogenesis that acts as an endogenous repair mechanism would have a significant impact on future therapeutic strategies for Parkinson's disease (PD. Several studies demonstrated dopaminergic modulation of neurogenesis in the subventricular zone (SVZ of the adult brain. Levodopa, the gold standard therapy for PD, causes an increase in homocysteine levels that induces neuronal death via N-methyl-D-aspartate (NMDA receptor. The present study investigated whether elevated homocysteine by levodopa treatment in a parkinsonian model would modulate neurogenesis via NMDA receptor signal cascade and compared the effect of levodopa and pramipexol (PPX on neurogenic activity. METHODOLOGY/PRINCIPAL FINDINGS: Neurogenesis was assessed in vitro using neural progenitor cells (NPCs isolated from the SVZ and in vivo with the BrdU-injected animal model of PD using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Modulation of homocysteine levels was evaluated using co-cultures of NPCs and astrocytes and PD animals. Immunochemical and Western blot analyses were used to measure neurogenesis and determine the cell death signaling. Levodopa treatment increased release of homocysteine on astrocytes culture media as well as in plasma and brain of PD animals. Increased homocysteine by levodopa led to increased apoptosis of NPCs through the NMDA receptor-dependent the extracellular signal-regulated kinase (ERK signaling pathways. The administration of a NMDA antagonist significantly attenuated apoptotic cell death in levodopa-treated NPCs and markedly increased the number of BrdU-positive cells in the SVZ of levodopa-treated PD animals. Comparative analysis revealed that PPX treatment significantly increased the number of NPCs and BrdU-positive cells in the SVZ of PD animals compared to levodopa treatment. Our present study demonstrated that increased homocysteine by levodopa has a detrimental effect on neurogenesis through NMDA receptor

The Two Faces of Selective Memory Retrieval: Recall Specificity of the Detrimental but Not the Beneficial Effect

Science.gov (United States)

Bäuml, Karl-Heinz T.; Dobler, Ina M.

2015-01-01

Depending on the degree to which the original study context is accessible, selective memory retrieval can be detrimental or beneficial for the recall of other memories (Bäuml & Samenieh, 2012). Prior work has shown that the detrimental effect of memory retrieval is typically recall specific and does not arise after restudy trials, whereas…

Environmental risk assessment of airborne emission from chinese coal-fired power plants with public health detriment criteria

International Nuclear Information System (INIS)

He Huimin; Pan Ziqiang; Zhang Yongxing; Xia Yihua

1997-01-01

On the basis of investigation of types of dust removers and their efficiency in Chinese coal-fired power plants, human health detriment of airborne non-radioactive and radioactive emissions from the power plants is assessed with public health detriment assessment method. The results show that the risk is primarily from airborne non-radioactive emission

The effect of utilising age and sex dependent factors for calculating detriment from medical irradiation

International Nuclear Information System (INIS)

Mettler, F.A.; Davis, M.; Moseley, R.D.; Kelsey, C.A.

1986-01-01

Proposals have been made for a quantity that can be used to estimate possible detriment from medical radiology better than the ICRP's collective effective dose equivalent. One such approach utilises age and sex dependent 'weighting' factors. The magnitude of the effect obtained by utilising such factors when applied to an actual population has not been previously assessed. When age and sex dependent weighting factors are applied to diagnostic medical radiology for all hospital examinations conducted in the United States in 1980, estimates of detriment are reduced by one-third. (author)

Evaluating Past and Future USCG Use of Ohmsett Test Facility

Science.gov (United States)

2016-10-01

of Pages 22 22. Price Evaluating Past and Future USCG Use of Ohmsett Test Facility iv UNCLAS//Public | | CG-926 RDC | M. Fitzpatrick, et al...Opportunity Skimming System WEC Wave energy converter Evaluating Past and Future USCG Use of Ohmsett Test Facility x UNCLAS//Public | | CG-926 RDC | M...Date Summary of Effort OCT-NOV 1993 Vessel of Opportunity Skimming System (VOSS) (5 Weeks) APR-JUN 1996 Spilled Oil Recovery System (SORS) (8 Weeks

Evaluation of restoration mechanisms for future services using Carrier Ethernet

DEFF Research Database (Denmark)

Wessing, Henrik; Berger, Michael Stübert; Gestsson, H.M.

2010-01-01

In this paper, we evaluate and classify future service according to their requirements for delay, loss and bandwidth. The most demanding services include IPTV in different forms, hence IPTV is used as a representative for future services. Carrier Ethernet technologies are introduced with special...... focus on its OAM functionalities, and it is evaluated how IPTV performs in case of link failures on a Carrier Ethernet implementation. It is concluded that OAM update times of 10 ms is required to provide acceptable restoration performance in case of errors....

Evaluation of Voltage Control Approaches for Future Smart Distribution Networks

Directory of Open Access Journals (Sweden)

Pengfei Wang

2017-08-01

Full Text Available This paper evaluates meta-heuristic and deterministic approaches for distribution network voltage control. As part of this evaluation, a novel meta-heuristic algorithm, Cuckoo Search, is applied for distribution network voltage control and compared with a deterministic voltage control algorithm, the oriented discrete coordinate decent method (ODCDM. ODCDM has been adopted in a state-of-the-art industrial product and applied in real distribution networks. These two algorithms have been evaluated under a set of test cases, which were generated to represent the voltage control problems in current and future distribution networks. Sampled test results have been presented, and findings have been discussed regarding the adoption of different optimization algorithms for current and future distribution networks.

Stair climbing is more detrimental to the cement in hip replacement than walking

NARCIS (Netherlands)

Stolk, J.; Verdonschot, N.J.J.; Huiskes, H.W.J.

2002-01-01

Stair climbing may be detrimental to cemented total hip arthroplasties, because it subjects the reconstruction to high torsional loads. The current study investigated how stair climbing contributes to damage accumulation in the cement around a femoral stem compared with walking, taking into account

Cancer risk as a radiation detriment

International Nuclear Information System (INIS)

Servomaa, A.; Komppa, T.; Servomaa, K.

1992-11-01

Potential radiation detriment means a risk of cancer or other somatic disease, genetic damage of fetal injury. Quantative information about the relation between a radiation dose and cancer risk is needed to enable decision-making in radiation protection. However, assessment of cancer risk by means of the radiation dose is controversial, as epidemiological and biological information about factors affecting the origin of cancers show that risk assessment is imprecise when the radiation dose is used as the only factor. Focusing on radiation risk estimates for breast cancer, lung cancer and leukemia, the report is based on the models given in the Beir V report, on sources of radiation exposure and the uncertainty of risk estimates. Risk estimates are assessed using the relative risk model and the cancer mortality rates in Finland. Cancer incidence and mortality rates for men and women are shown in graphs as a function of age and time. Relative risks are shown as a function of time after exposure and lifetime risks as a function of age at exposure. Uncertainty factors affecting the radiation risk are examined from the point of view of epidemiology and molecular biology. (orig.)

Does physical activity attenuate, or even eliminate, the detrimental association of sitting time with mortality?

DEFF Research Database (Denmark)

Ekelund, Ulf; Steene-Johannessen, Jostein; Brown, Wendy J

2016-01-01

BACKGROUND: High amounts of sedentary behaviour have been associated with increased risks of several chronic conditions and mortality. However, it is unclear whether physical activity attenuates or even eliminates the detrimental effects of prolonged sitting. We examined the associations of seden......BACKGROUND: High amounts of sedentary behaviour have been associated with increased risks of several chronic conditions and mortality. However, it is unclear whether physical activity attenuates or even eliminates the detrimental effects of prolonged sitting. We examined the associations...... of sedentary behaviour and physical activity with all-cause mortality. METHODS: We did a systematic review, searching six databases (PubMed, PsycINFO, Embase, Web of Science, Sport Discus, and Scopus) from database inception until October, 2015, for prospective cohort studies that had individual level exposure...

Beneficial and Detrimental Effects of UV on Aquatic Organisms: Implications of Spectral Variation

NARCIS (Netherlands)

Williamson, C.E.; Neale, P.J.; Grad, G.; Lange, de H.J.; Hargreaves, B.R.

2001-01-01

Solar ultraviolet radiation (UVR) may have beneficial as well as detrimental effects on living systems. For example, UV-B radiation (280¿320 nm) is generally damaging, while UV-A radiation (320¿400 nm) may cause damage or stimulate beneficial photorepair of UV-B damage. The nature of both direct and

Detrimental effects of geldanamycin on adults and larvae of Trichinella spiralis

Directory of Open Access Journals (Sweden)

Othman A. A.

2016-06-01

Full Text Available Trichinellosis is a zoonotic disease affecting mainly the temperate regions. The treatment is a challenge for the physician, and the available therapy is far from ideal. Therefore, this work aimed to evaluate the effect of heat shock protein 90 inhibitor, geldanamycin, on the adult worms and larvae of Trichinella spiralis. This research comprised an in vivo study in which T. spiralis-infected mice were treated by two different doses of geldanamycin, thereafter larval count and pathological changes were determined in the muscles. Meanwhile, the in vitro study investigated the effect of two different concentrations of geldanamycin on adult worms and larvae of T. spiralis via transmission electron microscopy. The in vivo study showed significant reduction of muscle larval counts under the effect of geldanamycin. Moreover, characteristic changes were noted as regards the parasite and the inflammatory response. The in vitro study revealed degenerative changes in the body wall of larvae and adults of T. spiralis under the influence of geldanamycin. In conclusion, heat shock protein 90 inhibitor, geldanamycin, seems to have detrimental effects on the adults and larvae of T. spiralis. It, or one of its derivatives, could be an adjuvant to anthelmintic therapy of trichinellosis, but more studies are warranted to establish its usefulness.

A comparison of the radiological and chemical detriments in man

International Nuclear Information System (INIS)

Maximilien, R.

1988-04-01

Following a review of the knowledge on the assessment of chemical carcinogens, a comparison between chemical and radiological detriments is attempted from a methodological standpoint. The main problem in chemical carcinogenesis is to get proofs, the discussion bearing on the identity of the interspecific biological mechanisms on account of the nearly constant lack of epidemiological data. The quantification of the neoplastic effects of chemical agents has not been fully developed and can be considered case by case only by carrying out a critical examination of the indicators available in order to extrapolate to man or to low doses [fr

Older Adults' Perceptions of Nutrition as Protective against Detrimental Effects of Environmental Pollution

Science.gov (United States)

Dunn, Kristina; Gaetke, Lisa; Stephenson, Tammy; Brewer, Dawn

2017-01-01

The aging process makes older adults vulnerable to the detrimental health effects of environmental contaminants. Our study assessed older adults' perceptions regarding diet as protective against environmental contaminants, levels of concern about exposure to environmental contaminants, and interest in learning about protective food-related…

Value orientation and payment for ecosystem services: Perceived detrimental consequences lead to willingness-to-pay for ecosystem services.

Science.gov (United States)

Obeng, Elizabeth Asantewaa; Aguilar, Francisco Xavier

2018-01-15

This research analyzed whether the three distinct value orientations posited under the Value-Belief-Norm (VBN) model determine willingness-to-pay (WTP) for a payment for ecosystem services (PES) program. A survey instrument gathered U.S. residents' knowledge and attitudes toward ecosystem services and PES, and elicited WTP for the restoration of a hypothetical degraded forest watershed for improved ecosystem services. Data from over 1000 respondents nationwide were analyzed using exploratory factor analysis (EFA) and ordered logistic regression. Urban respondents were more familiar with the concepts of ecosystem service and PES than rural respondents but familiarity did not yield statistically different WTP estimates. Based on results from the EFA, we posit that latent value orientations might be distinguished as 'detrimental', 'biospheric' and 'beneficial (egoistic)' - as compared to 'altruistic', 'biospheric' and 'egoistic' as suggested in the VBN's general awareness of consequences scale. Awareness of biospheric and detrimental consequences along with ascriptions to personal norms had positive and significant effects on stated WTP. Beneficial (egoistic) value orientation was negatively associated with WTP and carried a negative average WTP per household per year (US$ -30.48) for the proposed PES restoration program as compared with biospheric (US$ 15.53) and detrimental (US$ 3.96) orientations. Besides personal norms, awareness of detrimental consequences to human wellbeing from environmental degradation seems the stronger driver of WTP for the restoration and protection of forest watershed ecosystem services under a PES program. Copyright © 2017 Elsevier Ltd. All rights reserved.

Australia's Unprecedented Future Temperature Extremes Under Paris Limits to Warming

Science.gov (United States)

Lewis, Sophie C.; King, Andrew D.; Mitchell, Daniel M.

2017-10-01

Record-breaking temperatures can detrimentally impact ecosystems, infrastructure, and human health. Previous studies show that climate change has influenced some observed extremes, which are expected to become more frequent under enhanced future warming. Understanding the magnitude, as a well as frequency, of such future extremes is critical for limiting detrimental impacts. We focus on temperature changes in Australian regions, including over a major coral reef-building area, and assess the potential magnitude of future extreme temperatures under Paris Agreement global warming targets (1.5°C and 2°C). Under these limits to global mean warming, we determine a set of projected high-magnitude unprecedented Australian temperature extremes. These include extremes unexpected based on observational temperatures, including current record-breaking events. For example, while the difference in global-average warming during the hottest Australian summer and the 2°C Paris target is 1.1°C, extremes of 2.4°C above the observed summer record are simulated. This example represents a more than doubling of the magnitude of extremes, compared with global mean change, and such temperatures are unexpected based on the observed record alone. Projected extremes do not necessarily scale linearly with mean global warming, and this effect demonstrates the significant potential benefits of limiting warming to 1.5°C, compared to 2°C or warmer.

The two faces of selective memory retrieval: Earlier decline of the beneficial than the detrimental effect with older age.

Science.gov (United States)

Aslan, Alp; Schlichting, Andreas; John, Thomas; Bäuml, Karl-Heinz T

2015-12-01

Recent work with young adults has shown that, depending on study context access, selective memory retrieval can both impair and improve recall of other memories (Bäuml & Samenieh, 2010). Here, we investigated the 2 opposing effects of selective retrieval in older age. In Experiment 1, we examined 64 younger (20-35 years) and 64 older participants (above 60 years), and manipulated study context access using list-method directed forgetting. Whereas both age groups showed a detrimental effect of selective retrieval on to-be-remembered items, only younger but not older adults showed a beneficial effect on to-be-forgotten items. In Experiment 2, we examined 112 participants from a relatively wide age range (40-85 years), and manipulated study context access by varying the retention interval between study and test. Overall, a detrimental effect of selective retrieval arose when the retention interval was relatively short, but a beneficial effect when the retention interval was prolonged. Critically, the size of the beneficial but not the detrimental effect of retrieval decreased with age and this age-related decline was mediated by individuals' working memory capacity, as measured by the complex operation span task. Together, the results suggest an age-related dissociation in retrieval dynamics, indicating an earlier decline of the beneficial than the detrimental effect of selective retrieval with older age. (c) 2015 APA, all rights reserved).

Detrimental Effects of Performance-Related Pay in the Public Sector?

DEFF Research Database (Denmark)

Bregn, Kirsten

2013-01-01

Performance-related pay has been a key ingredient in New Public Management reforms. Nevertheless, the research presented here indicates some adverse effects of such incentives. These incentives may impair an initial motivation to work and change the norms that guide behavior. An issue which...... in particular has been given insufficient attention is fairness. Findings drawn from experimental economics supported by field studies demonstrate that perceived unfairness may have important negative effects on performance. The implication of a broader perspective in the analysis of performance-related pay...... in the public sector is that such a pay system, contrary to its aim, may have detrimental effects on performance....

Analysis and assessment of the detriment in interventional radiology using biological dosimetry methods

International Nuclear Information System (INIS)

Montoro, A.; Almonacid, M.; Villaescusa, J.I.; Barquinero, J.F.; Rodriguez, P.; Barrios, L.; Verdu, G.; Ramos, M.

2006-01-01

Interventional radiologist and staff members usually are exposed to high levels of scattered radiation. As a result, the exposition to radiation procedures can produce detrimental effects that we would have to know. Effective dose is the quantity that better estimates the radiation risk. For this study we have realized an estimation of the radiological detriment to exposed workers of the Hospital la Fe de Valencia. For it, have been used physical doses registered in detectors T.L.D., and doses estimated by biological dosimetry in lymphocytes of peripheral blood. There has been estimated for every case the probability of effect of skin cancer and of non-solid cancers (leukaemia, lymphoma and myeloma), being compared with the baseline probability of natural effect. Biological doses were obtained by extrapolating the yield of dicentrics and translocations to their respective dose -effect curves. The discrepancies observed between physically recorded doses and biological estimated doses indicate that workers did not always wear their dosimeters or the dosimeters were not always in the radiation field. Cytogenetic studies should be extended to more workers to assess the risk derived from their occupational exposure. (authors)

Analysis and assessment of the detriment in interventional radiology using biological dosimetry methods

Energy Technology Data Exchange (ETDEWEB)

Montoro, A.; Almonacid, M.; Villaescusa, J.I. [Hospital Univ. la Fe de Valen cian, Servicio de Proteccion Radiologica, Valencia (Spain); Barquinero, J.F.; Rodriguez, P. [Universitat Autonom a de Barcelona, Servicio de Dosimetria Biologica, Unidad de Antropologia, Departamento de Biologia Animal, Vegetal y Ecologia., Barcelona (Spain); Barrios, L. [Universidad Autonoma de Barcelona, Dept. de Biologia Celular y Fisiologia. Unidad de Biologia Celular, Barcelona (Spain); Verdu, G.; Ramos, M. [Universidad Politecnica de Valencia, Dept. de Ingenieria Quimica y Nuclear, Valencia, (Spain)

2006-07-01

Interventional radiologist and staff members usually are exposed to high levels of scattered radiation. As a result, the exposition to radiation procedures can produce detrimental effects that we would have to know. Effective dose is the quantity that better estimates the radiation risk. For this study we have realized an estimation of the radiological detriment to exposed workers of the Hospital la Fe de Valencia. For it, have been used physical doses registered in detectors T.L.D., and doses estimated by biological dosimetry in lymphocytes of peripheral blood. There has been estimated for every case the probability of effect of skin cancer and of non-solid cancers (leukaemia, lymphoma and myeloma), being compared with the baseline probability of natural effect. Biological doses were obtained by extrapolating the yield of dicentrics and translocations to their respective dose -effect curves. The discrepancies observed between physically recorded doses and biological estimated doses indicate that workers did not always wear their dosimeters or the dosimeters were not always in the radiation field. Cytogenetic studies should be extended to more workers to assess the risk derived from their occupational exposure. (authors)

The Many Faces of Part-List Cuing—Evidence for the Interplay Between Detrimental and Beneficial Mechanisms

Directory of Open Access Journals (Sweden)

Eva-Maria Lehmer

2018-05-01

Full Text Available If participants study a list of items and, at test, receive a random selection of the studied items as retrieval cues, then such cuing often impairs recall of the remaining items. This effect, referred to as part-list cuing impairment, is a well-established finding in memory research that, over the years, has been attributed to quite different cognitive mechanisms. Here, we provide a review of more recent developments in research on part-list cuing. These developments (i suggest a new view on part-list cuing impairment and a critical role of encoding for the effect, (ii identify conditions in which part-list cuing impairment can turn into part-list cuing facilitation, and (iii relate research on part-list cuing to a phenomenon from social memory, known as collaborative inhibition. The recent developments also include a new multi-mechanisms account, which attributes the effects of cuing to the interplay between detrimental mechanisms—like blocking, inhibition, or strategy disruption—and beneficial mechanisms—like context reactivation. The account provides a useful theoretical framework to describe both older and newer findings. It may guide future work on part-list cuing and may also motivate new research on collaborative inhibition.

Real cause of detrimental carbonation in chemically stabilized layers and possible solutions

CSIR Research Space (South Africa)

Botha, PB

2005-10-01

Full Text Available to determine the other reaction that may take place in the material. KEYWORDS CARBONATION/ CHEMICAL REACTIONS/ WATER CURING/ NEW TESTING PROTOCOL 1 INTRODUCTION This paper deals with the problems related to the “curing” of the stabilized layers... than CO2 driven. In actually fact the so-called “detrimental carbonation” chemical reaction cannot even take place without free water being available. The water is normally supplied by the specified curing 2 technique to keep the layer moist...

Cognitive Evaluation Theory: A Meta-Analytic Review of the Literature.

Science.gov (United States)

Rummel, Amy; Feinberg, Richard

1988-01-01

Employed meta-analysis to determine existence of the detrimental effects of extrinsic rewards on intrinsic motivation. Results showed that within strictly defined parameters the phenomenon concerning the detrimental effects of reward described in Deci's Cognitive Evaluation Theory did exist. (Author/NB)

Balancing the benefits and detriments among women targeted by the Norwegian Breast Cancer Screening Program.

Science.gov (United States)

Hofvind, Solveig; Román, Marta; Sebuødegård, Sofie; Falk, Ragnhild S

2016-12-01

To compute a ratio between the estimated numbers of lives saved from breast cancer death and the number of women diagnosed with a breast cancer that never would have been diagnosed during the woman's lifetime had she not attended screening (epidemiologic over-diagnosis) in the Norwegian Breast Cancer Screening Program. The Norwegian Breast Cancer Screening Program invites women aged 50-69 to biennial mammographic screening. Results from published studies using individual level data from the programme for estimating breast cancer mortality and epidemiologic over-diagnosis comprised the basis for the ratio. The mortality reduction varied from 36.8% to 43% among screened women, while estimates on epidemiologic over-diagnosis ranged from 7% to 19.6%. We computed the average estimates for both values. The benefit-detriment ratio, number of lives saved, and number of women over-diagnosed were computed for different scenarios of reduction in breast cancer mortality and epidemiologic over-diagnosis. For every 10,000 biennially screened women, followed until age 79, we estimated that 53-61 (average 57) women were saved from breast cancer death, and 45-126 (average 82) were over-diagnosed. The benefit-detriment ratio using average estimates was 1:1.4, indicating that the programme saved about one life per 1-2 women with epidemiologic over-diagnosis. The benefit-detriment ratio estimates of the Norwegian Breast Cancer Screening Program, expressed as lives saved from breast cancer death and epidemiologic over-diagnosis, should be interpreted with care due to substantial uncertainties in the estimates, and the differences in the scale of values of the events compared. © The Author(s) 2016.

Radiation protection recommendations on dose limits: the role of the NCRP and the ICRP and future developments

International Nuclear Information System (INIS)

Sinclair, Warren K.

1995-01-01

The purpose of this paper is to review the role of the National Council on Radiation Protection and Measurements (NCRP) and the International Commission on Radiological Protection (ICRP) in making recommendations on dose limits for ionizing radiation exposure for workers and for the public. The text describes the new limits for workers and public recommended by ICRP in 1991 and NCRP in 1993 and the composition of the radiation health detriment on which they are based. The main component of this detriment is the risk of radiation induced cancer which is now estimated to be about three times greater than a decade or so earlier. Uncertainties in these risk estimates are discussed. Some special radiation protection problems, such as those for the embryo or fetus are described. The article also addresses future progress in radiation protection particularly with regard to future improvements in the scientific basis for radiation protection recommendations

The detrimental effects of extrinsic reinforcement on "Intrinsic motivation".

Science.gov (United States)

Dickinson, A M

1989-01-01

Extrinsic consequences have been criticized on the grounds that they decrease intrinsic motivation or internally initiated behavior. Two popular rationales for this criticism, Lepper's overjustification hypothesis (1981) and Deci's motivational theory (Deci & Ryan, 1985), are reviewed and the criticism is then redefined behaviorally. "Intrinsically controlled" behavior is defined as behavior maintained by response-produced reinforcers, and the question concerning extrinsic consequences is thus restated as follows: When behavior is maintained by response-produced stimuli, does extrinsic reinforcement decrease the reinforcing value of those stimuli? The empirical support for this detrimental effect is summarized briefly, and several possible explanations for the phenomenon are offered. Research results that reflect on the effect's generality and social significance are discussed next, with the conclusion that the effect is transient and not likely to occur at all if extrinsic rewards are reinforcing, noncompetitive, based on reasonable performance standards, and delivered repetitively.

Study and Evaluation of Current and Future Aircraft Loaders

Science.gov (United States)

1986-08-01

detonation intense Electromagnetic Pulse Eergy (DIP) is gene - rated which could seriously affect the electronic equipment. 2-105 The intense...speciality efforts, such as integrated logistics support (ILS), human factors engineering ( HFE ), and reliability, availability and m aintainability...task analyiis is outlined in detail in Appendix C: Human Fac- tors Enqineering Study and Evaluation of Current and Future Aircraft Loaders. The HFE

Sustainability performance evaluation: Literature review and future directions.

Science.gov (United States)

Büyüközkan, Gülçin; Karabulut, Yağmur

2018-07-01

Current global economic activities are increasingly being perceived as unsustainable. Despite the high number of publications, sustainability science remains highly dispersed over diverse approaches and topics. This article aims to provide a structured overview of sustainability performance evaluation related publications and to document the current state of literature, categorize publications, analyze and link trends, as well as highlight gaps and provide research recommendations. 128 articles between 2007 and 2018 are identified. The results suggest that sustainability performance evaluation models shall be more balanced, suitable criteria and their interrelations shall be well defined and subjectivity of qualitative criteria inherent to sustainability indicators shall be considered. To address this subjectivity, group decision-making techniques and other analytical methods that can deal with uncertainty, conflicting indicators, and linguistic evaluations can be used in future works. By presenting research gaps, this review stimulates researchers to establish practically applicable sustainability performance evaluation frameworks to help assess and compare the degree of sustainability, leading to more sustainable business practices. The review is unique in defining corporate sustainability performance evaluation for the first time, exploring the gap between sustainability accounting and sustainability assessment, and coming up with a structured overview of innovative research recommendations about integrating analytical assessment methods into conceptual sustainability frameworks. Copyright © 2018 Elsevier Ltd. All rights reserved.

Intranasal vaccination promotes detrimental Th17-mediated immunity against influenza infection.

Directory of Open Access Journals (Sweden)

Asher Maroof

2014-01-01

Full Text Available Influenza disease is a global health issue that causes significant morbidity and mortality through seasonal epidemics. Currently, inactivated influenza virus vaccines given intramuscularly or live attenuated influenza virus vaccines administered intranasally are the only approved options for vaccination against influenza virus in humans. We evaluated the efficacy of a synthetic toll-like receptor 4 agonist CRX-601 as an adjuvant for enhancing vaccine-induced protection against influenza infection. Intranasal administration of CRX-601 adjuvant combined with detergent split-influenza antigen (A/Uruguay/716/2007 (H3N2 generated strong local and systemic immunity against co-administered influenza antigens while exhibiting high efficacy against two heterotypic influenza challenges. Intranasal vaccination with CRX-601 adjuvanted vaccines promoted antigen-specific IgG and IgA antibody responses and the generation of polyfunctional antigen-specific Th17 cells (CD4(+IL-17A(+TNFα(+. Following challenge with influenza virus, vaccinated mice transiently exhibited increased weight loss and morbidity during early stages of disease but eventually controlled infection. This disease exacerbation following influenza infection in vaccinated mice was dependent on both the route of vaccination and the addition of the adjuvant. Neutralization of IL-17A confirmed a detrimental role for this cytokine during influenza infection. The expansion of vaccine-primed Th17 cells during influenza infection was also accompanied by an augmented lung neutrophilic response, which was partially responsible for mediating the increased morbidity. This discovery is of significance in the field of vaccinology, as it highlights the importance of both route of vaccination and adjuvant selection in vaccine development.

The detrimental impact of maladaptive personality on public mental health : a challenge for psychiatric practice

OpenAIRE

Hengartner, Michael Pascal

2015-01-01

Experts in personality psychology and personality disorders have long emphasized the pervasive and persistent detrimental impact of maladaptive personality traits on mental health and functioning. However, in routine psychiatric practice, maladaptive personality is readily ignored and personality traits are seldom incorporated into clinical guidelines. The aim of this narrative review is to outline how pervasively personality influences public mental health and how personality thereby challen...

Detrimental effect of selection for milk yield on genetic tolerance to heat stress in purebred Zebu cattle: Genetic parameters and trends.

Science.gov (United States)

Santana, M L; Pereira, R J; Bignardi, A B; Filho, A E Vercesi; Menéndez-Buxadera, A; El Faro, L

2015-12-01

antagonism between production and tolerance to heat stress demonstrated by the negative genetic correlation between these components (-0.23). Monitoring trends of the genetic component of heat stress would be a reasonable measure to avoid deterioration in one of the main traits of Zebu cattle (i.e., high tolerance to heat stress). On the basis of current genetic trends, the need for future genetic evaluation of dairy Zebu animals for tolerance to heat stress cannot be ruled out. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

The detrimental effects of extrinsic reinforcement on “Intrinsic motivation”

Science.gov (United States)

Dickinson, Alyce M.

1989-01-01

Extrinsic consequences have been criticized on the grounds that they decrease intrinsic motivation or internally initiated behavior. Two popular rationales for this criticism, Lepper's overjustification hypothesis (1981) and Deci's motivational theory (Deci & Ryan, 1985), are reviewed and the criticism is then redefined behaviorally. “Intrinsically controlled” behavior is defined as behavior maintained by response-produced reinforcers, and the question concerning extrinsic consequences is thus restated as follows: When behavior is maintained by response-produced stimuli, does extrinsic reinforcement decrease the reinforcing value of those stimuli? The empirical support for this detrimental effect is summarized briefly, and several possible explanations for the phenomenon are offered. Research results that reflect on the effect's generality and social significance are discussed next, with the conclusion that the effect is transient and not likely to occur at all if extrinsic rewards are reinforcing, noncompetitive, based on reasonable performance standards, and delivered repetitively. PMID:22478013

Biological ensemble modeling to evaluate potential futures of living marine resources

DEFF Research Database (Denmark)

Gårdmark, Anna; Lindegren, Martin; Neuenfeldt, Stefan

2013-01-01

) as an example. The core of the approach is to expose an ensemble of models with different ecological assumptions to climate forcing, using multiple realizations of each climate scenario. We simulated the long-term response of cod to future fishing and climate change in seven ecological models ranging from...... model assumptions from the statistical uncertainty of future climate, and (3) identified results common for the whole model ensemble. Species interactions greatly influenced the simulated response of cod to fishing and climate, as well as the degree to which the statistical uncertainty of climate...... in all models, intense fishing prevented recovery, and climate change further decreased the cod population. Our study demonstrates how the biological ensemble modeling approach makes it possible to evaluate the relative importance of different sources of uncertainty in future species responses, as well...

Evaluating canalside hedgerows to determine future interventions.

Science.gov (United States)

Faiers, Adam; Bailey, Alison

2005-01-01

This paper describes a project undertaken during 2001/2002 which developed a method for valuing hedgerows adjacent to the inland waterway network of Great Britain. The method enables the landowner, British Waterways, to manage their valuable environmental asset to achieve a good level of biodiversity and robust habitat balanced against the heavy amenity use the 3000 km canal network endures. Valuation techniques were developed using a combination of new and existing ecological indices for components of biodiversity, hedgerow structure and amenity, and synthesised into an index in an innovative combined approach. The resultant index was then applied to a sample 20 km section of hedge alongside the Grand Union Canal in Southeast England. The results obtained reflect the hedgerows' present value, and highlight factors that might improve or limit their future increase in value. The results from the case study application also demonstrate that there is a positive relationship between hedgerow structure and biodiversity, and that hedgerows in urban areas are less biodiverse and structurally sound than those in rural areas. Furthermore, there is a zone within rural areas influenced by the adjacent urban areas and/or higher amenity use. The paper concludes with an assessment of the approaches' strengths and weaknesses with a view to its compatibility with other hedgerow evaluations, such as HEGS, its use by other agencies or landowners, and to aid hedgerow management and future development.

Futures market observations help in property evaluations

International Nuclear Information System (INIS)

Pickles, E.

1994-01-01

A standard approach to the valuation of petroleum properties and to project economics requires the calculation of present value of future cash flows. The technique is well-known and widely used in property evaluations, which are crucial to the acquisition activity in which independent producers recently have been so heavily engaged. But shortcomings of the standard approach also are well-known. Two significant problems are the choice of discount rate and the need to forecast prices. The appropriate discount rate depends upon the risk involved, and the correct relationship between risk and expected return may be difficult to determine. Oil price forecasts, meanwhile, are notoriously unreliable. These problems have led to adaptation of the option-valuation technique now widely and successfully used in the financial markets to the problem of valuing real assets, such as an oil field. In this context an option is the right, but not the obligation, to buy or sell an asset at some future time for a price (the exercise price) determined at the time the option is acquired. The important parameters are equilibrium price, volatility, and convenience yield, each of which can be projected on the basis of market data close at hand. Then the values can be combined with the production profile of an oil field to mathematically estimate present value. The valuation method is described

A Spatial Frequency Account of the Detriment that Local Processing of Navon Letters Has on Face Recognition

Science.gov (United States)

Hills, Peter J.; Lewis, Michael B.

2009-01-01

Five minutes of processing the local features of a Navon letter causes a detriment in subsequent face-recognition performance (Macrae & Lewis, 2002). We hypothesize a perceptual after effect explanation of this effect in which face recognition is less accurate after adapting to high-spatial frequencies at high contrasts. Five experiments were…

Protective and detrimental bystander effects induced by x-irradiation in the limb bud cell cultures of fetal mice

International Nuclear Information System (INIS)

Wang, B.; Ohyama, H.; Shang, Y.; Yukawa, O.; Aizawa, S.; Hayata, I.

2003-01-01

Full text: Radioadaptive response and bystander effect represent important phenomena in radiobiology with an impact on the novel bioresponse mechanisms and risk estimates. The micromass cultures of limb bud cells (LBCs) provide an in vitro cellular maturation system, in which progress of cellular proliferation and differentiation is comparably paralleled to that of in vivo. This paper reports for the first time the evidential correlation and interaction, which simultaneously exist in the micromass culture system, between radioadaptive response and bystander effect. A radioadaptive response was induced in LBCs of embryonic day 11 (E11) ICR mice. Conditioning irradiation of the E11 cells with 30 cGy resulted in a significant protective effect against the occurrence of apoptosis, inhibition of cellular proliferation and differentiation induced by a challenging dose of 5 Gy given next day. Both protective and detrimental bystander effects were observed, namely, irradiating 50% of the E11 cells with 30 cGy led to a successful induction of radioadaptive response, and irradiating 70% of the E12 cells with 5 Gy produced comparably the detrimental effect to that of when all the cells were irradiated. Further, the bystander effects were markedly vanished by pretreatment of the cells with inhibitors to block the gap junction-mediated intracellular communication. These results indicated that the bystander effect played an important role in both the induction of a protective effect by the conditioning dose and the detrimental effect by the challenging irradiation. Concerning the underlying mechanism, the gap junction-mediated intracellular communication was suggested being involved in the induction of the bystander effects

Predictors of future anabolic androgenic steroid use.

Science.gov (United States)

Wichstrøm, Lars

2006-09-01

To prospectively study the stability of anabolic androgenic steroid (AAS) use and predictors of AAS use, and to investigate whether AAS use alters the risk of later emotional and behavioral problems. Survey of a national sample of Norwegian high school students (age 15-19) in 1994 followed up in 1999 (N = 2924). Measures of frequent alcohol intoxication (50+ times per 12 months), cannabis use (12 months), hard drug use (12 months), being offered cannabis, eating problems, conduct problems, sexual debut before age 15, BMI, involvement in power sports, perceived physical appearance, and satisfaction with body parts were obtained. Life-time prevalence of AAS use were 1.9 and 0.8% in the follow-up period. Multivariate logistic regression revealed that future AAS use was predicted by young age, male gender, previous AAS use, involvement in power sports, and frequent alcohol intoxication. AAS use did not predict future emotional or behavioral problems other than reducing the risk of future frequent alcohol intoxication. Frequent alcohol intoxication and involvement in power sports appear to predict future AAS use. At the population level there was little stability in individual AAS use from adolescence to early adulthood. No detrimental effects of AAS use could be detected in this study, but low statistical power limits this conclusion.

Empirical evaluation of the efficiency of the Iberian power futures market

Directory of Open Access Journals (Sweden)

Álvaro Capitán Herráiz

2008-12-01

Full Text Available Market efficiency is analysed for the Iberian Power Futures Market and other European Power Markets, as well as other fuel markets through evaluation of ex-post Forward Risk Premium. The equilibrium price from compulsory call auctions for distribution companies within the framework of the Iberian Power Futures Market is not optimal for remuneration purposes as it seems to be slightly upward biased, though such a premium is not significant (only around 2% above the average of Settlement Prices. In the period considered (August 2006 to September 2008, monthly futures contracts behave similarly to quarterly contracts. Average risk premia have been positive in power and natural gas markets but negative in oil and coal markets. Different hypotheses are tested regarding increasing volatility with maturity and regarding Forward Risk Premium correlations (negative with variance of spot prices during delivery period and positive with skewness of spot prices during delivery period. Enlarged data sets are recommended for stronger test results. Energy markets tend to show limited levels of market efficiency. Regarding the emerging Iberian Power Futures Market, price efficiency is improved with market development and with further integration of European Regional Power Markets.

Detrimental Effect Elimination of Laser Frequency Instability in Brillouin Optical Time Domain Reflectometer by Using Self-Heterodyne Detection

Directory of Open Access Journals (Sweden)

Yongqian Li

2017-03-01

Full Text Available A useful method for eliminating the detrimental effect of laser frequency instability on Brillouin signals by employing the self-heterodyne detection of Rayleigh and Brillouin scattering is presented. From the analysis of Brillouin scattering spectra from fibers with different lengths measured by heterodyne detection, the maximum usable pulse width immune to laser frequency instability is obtained to be about 4 µs in a self-heterodyne detection Brillouin optical time domain reflectometer (BOTDR system using a broad-band laser with low frequency stability. Applying the self-heterodyne detection of Rayleigh and Brillouin scattering in BOTDR system, we successfully demonstrate that the detrimental effect of laser frequency instability on Brillouin signals can be eliminated effectively. Employing the broad-band laser modulated by a 130-ns wide pulse driven electro-optic modulator, the observed maximum errors in temperatures measured by the local heterodyne and self-heterodyne detection BOTDR systems are 7.9 °C and 1.2 °C, respectively.

Evaluation of Future Internet Technologies for Processing and Distribution of Satellite Imagery

Science.gov (United States)

Becedas, J.; Perez, R.; Gonzalez, G.; Alvarez, J.; Garcia, F.; Maldonado, F.; Sucari, A.; Garcia, J.

2015-04-01

Satellite imagery data centres are designed to operate a defined number of satellites. For instance, difficulties when new satellites have to be incorporated in the system appear. This occurs because traditional infrastructures are neither flexible nor scalable. With the appearance of Future Internet technologies new solutions can be provided to manage large and variable amounts of data on demand. These technologies optimize resources and facilitate the appearance of new applications and services in the traditional Earth Observation (EO) market. The use of Future Internet technologies for the EO sector were validated with the GEO-Cloud experiment, part of the Fed4FIRE FP7 European project. This work presents the final results of the project, in which a constellation of satellites records the whole Earth surface on a daily basis. The satellite imagery is downloaded into a distributed network of ground stations and ingested in a cloud infrastructure, where the data is processed, stored, archived and distributed to the end users. The processing and transfer times inside the cloud, workload of the processors, automatic cataloguing and accessibility through the Internet are evaluated to validate if Future Internet technologies present advantages over traditional methods. Applicability of these technologies is evaluated to provide high added value services. Finally, the advantages of using federated testbeds to carry out large scale, industry driven experiments are analysed evaluating the feasibility of an experiment developed in the European infrastructure Fed4FIRE and its migration to a commercial cloud: SoftLayer, an IBM Company.

Sleep Detriments Associated With Quick Returns in Rotating Shift Work: A Diary Study.

Science.gov (United States)

Vedaa, Øystein; Mørland, Erik; Larsen, Marit; Harris, Anette; Erevik, Eilin; Sivertsen, Børge; Bjorvatn, Bjørn; Waage, Siri; Pallesen, Ståle

2017-06-01

We aimed to compared sleep characteristics associated with quick returns (QRs, sleep diary (94.0% female, mean age 47.7 years). A multilevel fixed effects model was used to examine the sleep in QRs compared with two consecutive night shifts, two consecutive evening shifts, and two consecutive day shifts, respectively. None of the other shift transitions studied encumbered as many detriments as QRs, which included short sleep duration (5.6 hours), slightly prolonged sleep onset latency, more abrupt ending of main sleep period, increased sleepiness, and higher level of perceived stress on the following shift. The study emphasizes the need for sufficient time for rest and recuperation between shifts.

A critical evaluation of the validity of episodic future thinking: A clinical neuropsychology perspective.

Science.gov (United States)

Ward, Amanda M

2016-11-01

Episodic future thinking is defined as the ability to mentally simulate a future event. Although episodic future thinking has been studied extensively in neuroscience, this construct has not been explored in depth from the perspective of clinical neuropsychology. The aim of this critical narrative review is to assess the validity and clinical implications of episodic future thinking. A systematic review of episodic future thinking literature was conducted. PubMed and PsycInfo were searched through July 2015 for review and empirical articles with the following search terms: "episodic future thinking," "future mental simulation," "imagining the future," "imagining new experiences," "future mental time travel," "future autobiographical experience," and "prospection." The review discusses evidence that episodic future thinking is important for adaptive functioning, which has implications for neurological populations. To determine the validity of episodic future thinking, the construct is evaluated with respect to related constructs, such as imagination, episodic memory, autobiographical memory, prospective memory, narrative construction, and working memory. Although it has been minimally investigated, there is evidence of convergent and discriminant validity for episodic future thinking. Research has not addressed the incremental validity of episodic future thinking. Practical considerations of episodic future thinking tasks and related constructs in a clinical neuropsychological setting are considered. The utility of episodic future thinking is currently unknown due to the lack of research investigating the validity of episodic future thinking. Future work is discussed, which could determine whether episodic future thinking is an important missing piece in standard clinical neuropsychological assessment. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Soy protein is beneficial but high-fat diet and voluntary running are detrimental to bone structure in mice.

Science.gov (United States)

Yan, Lin; Graef, George L; Nielsen, Forrest H; Johnson, LuAnn K; Cao, Jay

2015-06-01

Physical activity and soy protein isolate (SPI) augmentation have been reported to be beneficial for bone health. We hypothesized that combining voluntary running and SPI intake would alleviate detrimental changes in bone induced by a high-fat diet. A 2 × 2 × 2 experiment was designed with diets containing 16% or 45% of energy as corn oil and 20% SPI or casein fed to sedentary or running male C57BL/6 mice for 14 weeks. Distal femurs were assessed for microstructural changes. The high-fat diet significantly decreased trabecular number (Tb.N) and bone mineral density (BMD) and increased trabecular separation (Tb.Sp). Soy protein instead of casein, regardless of fat content, in the diet significantly increased bone volume fraction, Tb.N, connectivity density, and BMD and decreased Tb.Sp. Voluntary running, regardless of fat content, significantly decreased bone volume fraction, Tb.N, connectivity density, and BMD and increased Tb.Sp. The high-fat diet significantly decreased osteocalcin and increased tartrate-resistant acid phosphatase 5b (TRAP 5b) concentrations in plasma. Plasma concentrations of osteocalcin were increased by both SPI and running. Running alleviated the increase in TRAP 5b induced by the high-fat diet. These findings demonstrate that a high-fat diet is deleterious, and SPI is beneficial to trabecular bone properties. The deleterious effect of voluntary running on trabecular structural characteristics indicates that there may be a maximal threshold of running beyond which beneficial effects cease and detrimental effects occur. Increases in plasma osteocalcin and decreases in plasma TRAP 5b in running mice suggest that a compensatory response occurs to counteract the detrimental effects of excessive running. Published by Elsevier Inc.

Evaluating the Navy’s Enlisted Accessions Testing Program Based on Future Talent Needs

Science.gov (United States)

2017-03-01

NAVY’S ENLISTED ACCESSIONS TESTING PROGRAM BASED ON FUTURE TALENT NEEDS by Shereka F. Riley March 2017 Thesis Advisor: Joseph Sullivan Co...REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE EVALUATING THE NAVY’S ENLISTED ACCESSIONS TESTING PROGRAM BASED ON FUTURE TALENT ...public release. Distribution is unlimited. 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) In recent years, non-defense related industries

Detrimental Effects of “Stretch” Goals in Specialty Substance Use Disorder Treatment Organizations

Science.gov (United States)

Lemoine, G. James; Blum, Terry C.; Roman, Paul M.

2016-01-01

Background “Stretch” goals, a rarely examined concept that represents seemingly impossible, highly ambitious organizational goals ostensibly established to fill performance gaps and motivate employees, are examined within a sample of substance use disorder (SUD) treatment centers in the United States in terms of their prevalence and effects on organizational behavior. Stretch goals are defined as “seemingly impossible” goals intended to motivate employees to achieve high performance. In light of the high level of environmental change and unpredictability faced by SUD treatment centers in recent decades, we theorize that stretch goals would be both common and often detrimental (in terms of capacity utilization rate and efficiency) in these settings. Methods In a longitudinal analysis of data from leaders of a representative U. S. national sample of 219 SUD treatment centers characterized by entrepreneurial management structures, we examined the prevalence of stretch goals and their impact on key outcome variables of capacity utilization rate and efficiency. Results Widespread adoption of stretch goals was found, with 43% of our sample falling within the stretch category. Stretch goals had a negative main effect on capacity utilization rate as compared to less ambitious challenging goals. Stretch and prior performance interacted to further predict capacity utilization rate, whereas stretch and slack resource availability interacted to predict center efficiency. Discussion Although stretch goals are frequently used in the SUD treatment industry, we find them mostly detrimental to performance. Stretch goals may enhance the efficiency of treatment centers with prior limited resource availability, but they are negatively associated with capacity utilization, especially in centers with a record of already strong performance. Despite the high prevalence of such goals and positive values centered on aspirational behavior, these results strongly suggest caution in

Processing of fine-grained W materials without detrimental phases and their mechanical properties at 200-432 K

Energy Technology Data Exchange (ETDEWEB)

Ishijima, Y.; Kannari, S. [International Research Center for Nuclear Materials Science, Institute for Materials Research (IMR), Tohoku University, Oarai, Ibaraki 311-1313 (Japan); Kurishita, H. [International Research Center for Nuclear Materials Science, Institute for Materials Research (IMR), Tohoku University, Oarai, Ibaraki 311-1313 (Japan)], E-mail: kurishi@imr.tohoku.ac.jp; Hasegawa, M. [International Research Center for Nuclear Materials Science, Institute for Materials Research (IMR), Tohoku University, Oarai, Ibaraki 311-1313 (Japan); Hiraoka, Y. [Department of Applied Physics, Okayama University of Science, 1-1 Ridai-cho, Okayama, Okayama 700-0005 (Japan); Takida, T.; Takebe, K. [A.L.M.T. TECH Inc., 2 Iwasekoshi-machi, Toyama, Toyama 931-8543 (Japan)

2008-01-25

Low-temperature ductility improvements of tungsten (W) materials with microstructures of fine grains and fine transition metal-carbide dispersoids require sufficient reductions for consolidates that are free from detrimental dispersoids of the W{sub 2}C phase. In this paper the cause of the occurrence of the detrimental W{sub 2}C phase is studied and an appropriate processing method for its prevention and nearly full densification of mechanically alloyed powder is shown. By applying the method W-0.3 wt%Ti-0.006 wt%C (W-0.3TiC-0.006C) specimens with a negligible amount of the W{sub 2}C phase and reductions up to 78% were prepared. It is found that W-0.3TiC-0.006C exhibits an appreciable ductility even at room temperature by three-point bend impact tests and static tensile tests, with the ductile-to-brittle transition temperature of around 260 K. The observed ductility is likely due to elongated, very thin grain structures of the material. For further ductility improvements, control of oxygen impurities to suppress decarburization during sintering and assure appropriate amounts of (Ti,W)C dispersoids is required.

Older Adults' Perceptions of Nutrition as Protective Against Detrimental Effects of Environmental Pollution.

Science.gov (United States)

Dunn, Kristina; Gaetke, Lisa; Stephenson, Tammy; Brewer, Dawn

2017-08-01

The aging process makes older adults vulnerable to the detrimental health effects of environmental contaminants. Our study assessed older adults' perceptions regarding diet being protective against environmental contaminants, their levels of concern about exposure, and their interest in learning about protective food-related strategies. A needs assessment to collect such information has not been conducted among older adults. Health fair survey results showed that they perceived diet as beneficial against contaminants, were concerned about health implications of exposure, and were interested in learning how to protect health through diet-related strategies. Results suggest that a nutrition-focused curriculum addressing how dietary strategies can help protect against environmental contaminants is needed for Extension professionals.

Safety design and evaluation policy for future FBRs in Japan

International Nuclear Information System (INIS)

Aizawa, Kiyoto

1991-01-01

The safety policy for fast breeder reactors (FBRs) has gradually matured in accordance with the development of FBRs. The safety assessment of the Japanese prototype FBR, Monju during the licensing process accelerated the maturity and the integration of knowledge and databases. Results are expected to be reflected in the establishment of the safety design and evaluation policy for FBRs. Although the methodologies and safety policies developed for LWRs are applicable in principle to future FBRs, it is neither rational nor realistic to treat safety only with these policies. It is recommended that one should develop the methodologies and safety policies starting from understanding of the inherent safety characteristics of FBR's through safety research, plant operating experience and design work. In the last few years, some technical committees were organized in Japan and have discussed key safety issues which are specific to FBRs in order to provide preparatory reports and to establish safety standards and guidelines for future commercial FBRs. (author)

The Detrimental Effects of Oxytocin-Induced Conformity on Dishonesty in Competition.

Science.gov (United States)

Aydogan, Gökhan; Jobst, Andrea; D'Ardenne, Kimberlee; Müller, Norbert; Kocher, Martin G

2017-06-01

Justifications may promote unethical behavior because they constitute a convenient loophole through which people can gain from immoral behavior and preserve a positive self-image at the same time. A justification that is widely used is rooted in conformity: Unethical choices become more permissible because one's peers are expected to make the same unethical choices. In the current study, we tested whether an exogenous alteration of conformity led to a lower inclination to adhere to a widely accepted norm (i.e., honesty) under the pressure of competition. We took advantage of the well-known effects of intranasally applied oxytocin on affiliation, in-group conformity, and in-group favoritism in humans. We found that conformity was enhanced by oxytocin, and this enhancement had a detrimental effect on honesty in a competitive environment but not in a noncompetitive environment. Our findings contribute to recent evidence showing that competition may lead to unethical behavior and erode moral values.

Conceptual Paradigms and Empirical Investigations for Evaluating INTELSAT's Past Performance and Future Prospects.

Science.gov (United States)

Snow, Marcellus S.

This paper summarizes the results of a recent study of the past performance and future prospects of the International Telecommunications Satellite (INTELSAT) Organization. First, an overview of INTELSAT's history is provided and major policy issues are detailed. Five alternative paradigms are then presented through which to evaluate INTELSAT's…

Modelling of the mammographic exposure conditions for radiological detriment study in the Valencian Breast Cancer Screening Programme

International Nuclear Information System (INIS)

Ferrer, S.; Ramos, M.; Villaescusa, J. I.; Verdu, G.; Salas, M. D.; Cuevas, M. D.

2005-01-01

Breast screening programmes are the best weapon to fight against breast cancer. Nevertheless, despite the benefits, this practice supposes a radiological risk that cannot be forgotten. In order to calculate breast glandular doses, different MCNP-4C2 models have been developed, simulating the exposure conditions. Radiological detriments have been transported from the population under study in the UNSCEAR 2000 to the Valencian Community, obtaining the detection-induced cancer ratio (DICR) for this population. (authors)

The Pilgaard-Dahl syndrome: laughter-induced pneumothorax - one of the many potentially detrimental consequences of laughter

DEFF Research Database (Denmark)

Andreasen, Dorthe Bach; El Fassi, Daniel

2010-01-01

In this article we propose the eponym Pilgaard-Dahl syndrome (named after two Danish revue actors). The syndrome consists of laughter-induced pneumothorax in smoking middle-aged men when exposed to hearty humour. The epidemiology and pathophysiology of spontaneous pneumothorax - in particular...... the Pilgaard-Dahl syndrome - is described. Finally, the occurrence of other detrimental effects of laughter as syncope, extreme bradycardia, asthma bouts, headache, stroke, death, and incontinence are described, as well as initiatives expected to minimise the occurrence of good mood are proposed....

Evaluating employee assistance programs. A review of methods, outcomes, and future directions.

Science.gov (United States)

Jerrell, J M; Rightmyer, J F

1982-01-01

Renewed interest in assisting troubled employees has led to an upsurge in the development of employee assistance programs, coupled with demands for demonstrable effectiveness. This review examines the nature and scope of these programs, their administrative and methodological context, and the types and outcomes of evaluation studies conducted thus far. Proposals for improving future investigations through a number of different approaches and strategies are then made.

An evaluation about the tools of doses calculation and future needs

International Nuclear Information System (INIS)

Thomassin, A.; Merle-Szeremeta, A.

1999-01-01

The purpose of this communication is to give an image of the situation in tools for doses calculation, and to look to the future. The Institute of Protection and Nuclear Safety, with its mission of dosimetric impact evaluation of any radioactive release or radioactive contamination is led to use numerous calculation tools. It appeared useful to take the stock of the situation on tools used at the I.P.S.N. but also out of the I.P.S.N.. (N.C.)

Perforin is detrimental to controlling [corrected] C. muridarum replication in vitro, but not in vivo.

Directory of Open Access Journals (Sweden)

Raymond M Johnson

Full Text Available CD4 T cells are critical for clearing experimental Chlamydia muridarum genital tract infections. Two independent in vitro CD4 T cell mechanisms have been identified for terminating Chlamydia replication in epithelial cells. One mechanism, requiring IFN-γ and T cell-epithelial cell contact, terminates infection by triggering epithelial production of nitric oxide to chlamydiacidal levels; the second is dependent on T cell degranulation. We recently demonstrated that there are two independent in vivo clearance mechanisms singly sufficient for clearing genital tract infections within six weeks; one dependent on iNOS, the other on Plac8. Redundant genital tract clearance mechanisms bring into question negative results in single-gene knockout mice. Two groups have shown that perforin-knockout mice were not compromised in their ability to clear C. muridarum genital tract infections. Because cell lysis would be detrimental to epithelial nitric oxide production we hypothesized that perforin was not critical for iNOS-dependent clearance, but posited that perforin could play a role in Plac8-dependent clearance. We tested whether the Plac8-dependent clearance was perforin-dependent by pharmacologically inhibiting iNOS in perforin-knockout mice. In vitro we found that perforin was detrimental to iNOS-dependent CD4 T cell termination of Chlamydia replication in epithelial cells. In vivo, unexpectedly, clearance in perforin knockout mice was delayed to the end of week 7 regardless of iNOS status. The discordant in vitro/in vivo results suggest that the perforin's contribution to bacterial clearance in vivo is not though enhancing CD4 T cell termination of Chlamydia replication in epithelial cells, but likely via a mechanism independent of T cell-epithelial cell interactions.

Predicting Nitrate Transport under Future Climate Scenarios beneath the Nebraska Management Systems Evaluation Area (MSEA) site

Science.gov (United States)

Li, Y.; Akbariyeh, S.; Gomez Peña, C. A.; Bartlet-Hunt, S.

2017-12-01

Understanding the impacts of future climate change on soil hydrological processes and solute transport is crucial to develop appropriate strategies to minimize adverse impacts of agricultural activities on groundwater quality. The goal of this work is to evaluate the direct effects of climate change on the fate and transport of nitrate beneath a center-pivot irrigated corn field in Nebraska Management Systems Evaluation Area (MSEA) site. Future groundwater recharge rate and actual evapotranspiration rate were predicted based on an inverse modeling approach using climate data generated by Weather Research and Forecasting (WRF) model under the RCP 8.5 scenario, which was downscaled from global CCSM4 model to a resolution of 24 by 24 km2. A groundwater flow model was first calibrated based on historical groundwater table measurement and was then applied to predict future groundwater table in the period 2057-2060. Finally, predicted future groundwater recharge rate, actual evapotranspiration rate, and groundwater level, together with future precipitation data from WRF, were used in a three-dimensional (3D) model, which was validated based on rich historic data set collected from 1993-1996, to predict nitrate concentration in soil and groundwater from the year 2057 to 2060. Future groundwater recharge was found to be decreasing in the study area compared to average groundwater recharge data from the literature. Correspondingly, groundwater elevation was predicted to decrease (1 to 2 ft) over the five years of simulation. Predicted higher transpiration data from climate model resulted in lower infiltration of nitrate concentration in subsurface within the root zone.

Television advertising of foodstuffs potentially detrimental to oral health--a content analysis and comparison of children's and primetime broadcasts.

Science.gov (United States)

Chestnutt, I G; Ashraf, F J

2002-06-01

The study aimed to examine the nature, content and duration of advertisements broadcast during children's television; determine the proportion of advertisements promoting food; identify the potential of the food advertised to be detrimental to oral health; and to compare the nature and content of advertisements aimed at children with those transmitted during evening 'primetime' television. Children's and primetime television, broadcast on a main independent terrestrial channel in South Wales were video recorded, 237 and 42 hours being analysed in total. Analysis of the recording resulted in a total of 3,236 commercials, of which 2,345 were broadcast during children's television and 891 in primetime. During children's TV, 62.5% of advertising time was devoted to foodstuffs, significantly greater (Padvertising foods during primetime. Of the time spent advertising foods, during children's television 73.4% was devoted to products deemed potentially detrimental to oral health (primarily high in sugar), compared to 18.6% similarly categorised during evening television. Commercials for products which have the potential to adversely affect oral health constitute a large proportion of advertising time during children's television. Current codes of the Independent Television Commission governing advertising directed at children should be reviewed.

Basic radiation protection training for nurses and paramedical personnel: Belgian experience and future perspectives

International Nuclear Information System (INIS)

Clarijs, T.; Coeck, M.; Van Bladel, Lodewijk; Fremout, An

2015-01-01

When using ionising radiation for medical diagnosis or treatment of patients, understanding of relevant radiation protection principles and issues is indispensable. In Belgium, nurses and paramedical staff are required to acquire knowledge for protecting the patient against the detrimental effects of ionising radiation by means of a vocational training course. The experience with and challenges for this training course are presented here from a lecturer's point of view, together with a proposal for a future approach that harmonises the training content, its level and quality, according to European recommended standards. (authors)

The Future of Principal Evaluation

Science.gov (United States)

Clifford, Matthew; Ross, Steven

2012-01-01

The need to improve the quality of principal evaluation systems is long overdue. Although states and districts generally require principal evaluations, research and experience tell that many state and district evaluations do not reflect current standards and practices for principals, and that evaluation is not systematically administered. When…

Classification of radiation effects for dose limitation purposes: history, current situation and future prospects

Science.gov (United States)

Hamada, Nobuyuki; Fujimichi, Yuki

2014-01-01

Radiation exposure causes cancer and non-cancer health effects, each of which differs greatly in the shape of the dose–response curve, latency, persistency, recurrence, curability, fatality and impact on quality of life. In recent decades, for dose limitation purposes, the International Commission on Radiological Protection has divided such diverse effects into tissue reactions (formerly termed non-stochastic and deterministic effects) and stochastic effects. On the one hand, effective dose limits aim to reduce the risks of stochastic effects (cancer/heritable effects) and are based on the detriment-adjusted nominal risk coefficients, assuming a linear-non-threshold dose response and a dose and dose rate effectiveness factor of 2. On the other hand, equivalent dose limits aim to avoid tissue reactions (vision-impairing cataracts and cosmetically unacceptable non-cancer skin changes) and are based on a threshold dose. However, the boundary between these two categories is becoming vague. Thus, we review the changes in radiation effect classification, dose limitation concepts, and the definition of detriment and threshold. Then, the current situation is overviewed focusing on (i) stochastic effects with a threshold, (ii) tissue reactions without a threshold, (iii) target organs/tissues for circulatory disease, (iv) dose levels for limitation of cancer risks vs prevention of non-life-threatening tissue reactions vs prevention of life-threatening tissue reactions, (v) mortality or incidence of thyroid cancer, and (vi) the detriment for tissue reactions. For future discussion, one approach is suggested that classifies radiation effects according to whether effects are life threatening, and radiobiological research needs are also briefly discussed. PMID:24794798

Evaluation of the ORNL area for future waste burial facilities

International Nuclear Information System (INIS)

Lomenick, T.F.; Byerly, D.W.; Gonzales, S.

1983-10-01

Additional waste-burial facilities will be needed at ORNL within this decade. In order to find environmentally acceptable sites, the ORNL area must be systematically evaluated. This document represents the first step in that selection process. Geologic and hydrologic data from the literature and minor field investigations are used to identify more favorable sites for Solid Waste Storage Area (SWSA) 7. Also underway at this time is a companion study to locate a Central Waste Storage Area which could be used in the future to accommodate wastes generated by the X-10, Y-12, and K-25 facilities. From the several watershed options available, the Whiteoak Creek drainage basin is selected as the most promising hydrologic regime. This area contains all past and present waste-disposal facilities and is thus already well monitored. The seven bedrock units within the ORNL area are evaluated as potential burial media. Shales of the Conasauga Group, which are currently used for waste burial in the Whiteoak Creek drainage basin, and the Knox Group are considered the leading candidates. Although the residuum derived from and overlying the Knox dolomite has many favorable characteristics and may be regarded as having a high potential for burial of low-level wastes, at the present it is unproven. Therefore, the Conasauga shales are considered a preferable option for SWSA 7 within the ORNL area. Since the Conasauga interval is currently used for waste burial, it is better understood. One tract in Melton Valley that is underlain by Conasauga shales is nominated for detailed site-characterization studies, and several other tracts are recommended for future exploratory drilling. Exploration is also suggested for a tract in the upper Whiteoak Creek basin where Knox residuum is the shallow subsurface material

Whole-brain radiation therapy for brain metastases: detrimental or beneficial?

International Nuclear Information System (INIS)

Gemici, Cengiz; Yaprak, Gokhan

2015-01-01

Stereotactic radiosurgery is frequently used, either alone or together with whole-brain radiation therapy to treat brain metastases from solid tumors. Certain experts and radiation oncology groups have proposed replacing whole-brain radiation therapy with stereotactic radiosurgery alone for the management of brain metastases. Although randomized trials have favored adding whole-brain radiation therapy to stereotactic radiosurgery for most end points, a recent meta-analysis demonstrated a survival disadvantage for patients treated with whole-brain radiation therapy and stereotactic radiosurgery compared with patients treated with stereotactic radiosurgery alone. However the apparent detrimental effect of adding whole-brain radiation therapy to stereotactic radiosurgery reported in this meta-analysis may be the result of inhomogeneous distribution of the patients with respect to tumor histologies, molecular histologic subtypes, and extracranial tumor stages between the groups rather than a real effect. Unfortunately, soon after this meta-analysis was published, even as an abstract, use of whole-brain radiation therapy in managing brain metastases has become controversial among radiation oncologists. The American Society of Radiation Oncology recently recommended, in their “Choose Wisely” campaign, against routinely adding whole-brain radiation therapy to stereotactic radiosurgery to treat brain metastases. However, this situation creates conflict for radiation oncologists who believe that there are enough high level of evidence for the effectiveness of whole-brain radiation therapy in the treatment of brain metastases

A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

Directory of Open Access Journals (Sweden)

Vasiliki (Vivian Iliadou

2017-11-01

Full Text Available Current notions of “hearing impairment,” as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other more sophisticated audiometric tests such as speech audiometry in noise or complex non-speech sound perception. This disorder, defined as “Auditory Processing Disorder” (APD or “Central Auditory Processing Disorder” is classified in the current tenth version of the International Classification of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order to further clarify the nature of APD and thus assist in optimum diagnosis and evidence-based management. This European consensus presents the main symptoms, conditions, and specific medical history elements that should lead to auditory processing evaluation. Consensus on definition of the disorder, optimum diagnostic pathway, and appropriate management are highlighted alongside a perspective on future research focus.

Evaluating fire danger in Brazilian biomes: present and future patterns

Science.gov (United States)

Silva, Patrícia; Bastos, Ana; DaCamara, Carlos; Libonati, Renata

2017-04-01

Climate change is expected to have a significant impact on fire occurrence and activity, particularly in Brazil, a region known to be fire-prone [1]. The Brazilian savanna, commonly referred to as cerrado, is a fire-adapted biome covering more than 20% of the country's total area. It presents the highest numbers of fire events, making it particularly susceptible to changes in climate. It is thus essential to understand the present fire regimes in Brazilian biomes, in order to better evaluate future patterns. The CPTEC/INPE, the Brazilian Center for Weather Forecasting and Climate Research at the Brazilian National Institute of Space Research developed a fire danger index based on the occurrence of hundreds of thousands of fire events in the main Brazilian biomes [2]: the Meteorological Fire Danger Index (MFDI). This index indicates the predisposition of vegetation to be burned on a given day, for given climate conditions preceding that day. It relies on daily values of air temperature, relative humidity, accumulated precipitation and vegetation cover. In this study we aim to access the capability of the MFDI to accurately replicate present fire conditions for different biomes, with a special focus on cerrado. To this end, we assess the link between the MFDI as calculated by three different reanalysis (ERA-Interim, NCEP/DOE Reanalysis 2 and MERRA-2) and the observed burned area. We further calculate the validated MFDI using a regional climate model, the RCA4 as forced by EC-Earth from CORDEX, to understand the ability of the model to characterize present fire danger. Finally, the need to calibrate the model to better characterize future fire danger was also evaluated. This work was developed within the framework of the Brazilian Fire-Land-Atmosphere System (BrFLAS) Project financed by the Portuguese and Brazilian science foundations, FCT and FAPESP (project references FAPESP/1389/2014 and 2014/20042-2). [1] KRAWCHUK, M.A.; MORITZ, M.A.; PARISIEN, M.A.; VAN DORN, J

[RehaFuturReal®: Evaluation of Implementation in Organizational Structure and in Counseling Process - An Overview of Results].

Science.gov (United States)

Arling, V; Knispel, J; Spijkers, W

2016-08-01

Due to prevailing future challenges in vocational rehabilitation, development process RehaFutur (BMAS) was initiated. In this context, recommendations were made to secure a future-oriented, innovative vocational rehabilitation in Germany. Deutsche Rentenversicherung (DRV) Westfalen transferred these recommendations into a new and applicable counseling concept RehaFutuReal(®). Rehabilitation managers (RM) are central protagonists in counseling process. Therefore, RehaFuturReal(®) focused on optimization of counseling performance. To achieve this aim, rehabilitation managers were taught to work with a case management (CM) based approach. RWTH Aachen supported RehaFuturReal(®) from an academic point of view and conducted a formative and summative evaluation. Primary aim of RWTH Aachen was to support DRV Westfalen during implementation of RehaFuturReal(®) into their organizational structure. Additionally, RWTH Aachen controlled whether transfer of RehaFutuReal(®) in counseling process was successful. From 04-01-13 until 12-31-14, RehaFuturReal(®) was tested by DRV Westfalen in the intervention district Dortmund with 10 RM. There were 3 selection criteria for the overall sample of N=320 insurants: participants were required to have an active employment status, suffered from integration issues and were in need of support to achieve vocational integration. Evaluation of RehaFuturReal(®) was realized summative (pre-post-comparison) and formative (process-orientated). Evaluative judgment regarding implementation in organizational structure and counseling process was performed by using three-stage-concept of Donabedian (quality of structure, process and results). Thereby, feedback of RM, insurants and employers was taken into account. Analysis of evaluation results revealed a positive overall impression. Implementation into organizational structure was successful on all 3 quality stages: concept of project and CM-training were an adequate basis and appropriately put

Calculation of the average radiological detriment of two samples from a breast screening programme

International Nuclear Information System (INIS)

Ramos, M.; Sanchez, A.M.; Verdu, G.; Villaescusa, J.I.; Salas, M.D.; Cuevas, M.D.

2002-01-01

In 1992 started in the Comunidad Valenciana the Breast Cancer Screening Programme. The programme is oriented to asymptomatic women between 45 and 65 years old, with two mammograms in each breast for the first time that participate and a simple one in later interventions. Between November of 2000 and March of 2001 was extracted a first sample of 100 woman records for all units of the programme. The data extracted in each sample were the kV-voltage, the X-ray tube load and the breast thickness and age of the woman exposed, used directly in dose and detriment calculation. By means of MCNP-4B code and according to the European Protocol for the quality control of the physical and technical aspects of mammography screening, the average total and glandular doses were calculated, and later compared

Using the effect of alcohol as a comparison to illustrate the detrimental effects of noise on performance

Directory of Open Access Journals (Sweden)

Brett R.C Molesworth

2013-01-01

Full Text Available The aim of the present research is to provide a user-friendly index of the relative impairment associated with noise in the aircraft cabin. As such, the relative effect of noise, at a level typical of an aircraft cabin was compared with varying levels of alcohol intoxication in the same subjects. Since the detrimental effect of noise is more pronounced on non-native speakers, both native English and non-native English speakers featured in the study. Noise cancelling headphones were also tested as a simple countermeasure to mitigate the effect of noise on performance. A total of 32 participants, half of which were non-native English speakers, completed a cued recall task in two alcohol conditions (blood alcohol concentration 0.05 and 0.10 and two audio conditions (audio played through the speaker and noise cancelling headphones. The results revealed that aircraft noise at 65 dB (A negatively affected performance to a level comparable to alcohol intoxication of 0.10. The results also supported previous research that reflects positively on the benefits of noise cancelling headphones in reducing the effects of noise on performance especially for non-native English speakers. These findings provide for personnel involved in the aviation industry, a user-friendly index of the relative impairment associated with noise in the aircraft cabin as compared with the effects of alcohol. They also highlight the benefits of a simple countermeasure such as noise cancelling headphones in mitigating some of the detrimental effects of noise on performance.

Bioinformatics tools and database resources for systems genetics analysis in mice-a short review and an evaluation of future needs

NARCIS (Netherlands)

Durrant, Caroline; Swertz, Morris A.; Alberts, Rudi; Arends, Danny; Moeller, Steffen; Mott, Richard; Prins, Pjotr; van der Velde, K. Joeri; Jansen, Ritsert C.; Schughart, Klaus

During a meeting of the SYSGENET working group 'Bioinformatics', currently available software tools and databases for systems genetics in mice were reviewed and the needs for future developments discussed. The group evaluated interoperability and performed initial feasibility studies. To aid future

Detrimental effects of perioperative blood transfusion

DEFF Research Database (Denmark)

Nielsen, Hans Jørgen

1995-01-01

Evidence suggests that perioperative allogeneic blood transfusion increases the risk of infectious complications after major surgery and of cancer recurrence after curative operation. This has been attributed to immunosuppression. Several authors have suggested that filtered whole blood and/or red...... cell concentrate, or leucocyte- and buffy coat-reduced red cells in artificial medium or their own plasma, may reduce postoperative immunosuppression. It was also anticipated that the use of autologous blood might minimize the risk of perioperative transfusion, but studies have unexpectedly shown...... similar postoperative infectious complications and cancer recurrence and/or survival rates in patients receiving autologous blood donated before operation and those receiving allogeneic blood. Future studies should identify common risk factors associated with blood storage....

Determination of doses to different organs and prediction of health detriment, after hypothetical accident in mtr reactor core

Energy Technology Data Exchange (ETDEWEB)

Amin, E A; Abd El-Ghani, A H [National Center of Nuclear Safety and Radiation Control Atomic Energy Authority, Cairo (Egypt)

1997-12-31

As a result of pypothetical accidents with release of high amount of fission products, the doses to different organs consequent upon inhalation of radioactive fission products are calculated. The processes are modeled using the ORIGIN and TIRION-4 codes: source term, containment and activity enclosure, time dependent activity behaviour in the building, and radiation exposure in the reactor building. Prediction of health detriments were calculated using ICRP-60 nominal probability coefficients and organ doses determined for bone, lung, and thyroid gland, after whole body exposure from internal inhalation and external emmersion. 11 tabs.

Distemper virus encephalitis exerts detrimental effects on hippocampal neurogenesis.

Science.gov (United States)

von Rüden, E-L; Avemary, J; Zellinger, C; Algermissen, D; Bock, P; Beineke, A; Baumgärtner, W; Stein, V M; Tipold, A; Potschka, H

2012-08-01

Despite knowledge about the impact of brain inflammation on hippocampal neurogenesis, data on the influence of virus encephalitis on dentate granule cell neurogenesis are so far limited. Canine distemper is considered an interesting model of virus encephalitis, which can be associated with a chronic progressing disease course and can cause symptomatic seizures. To determine the impact of canine distemper virus (CDV) infection on hippocampal neurogenesis, we compared post-mortem tissue from dogs with infection with and without seizures, from epileptic dogs with non-viral aetiology and from dogs without central nervous system diseases. The majority of animals with infection and with epilepsy of non-viral aetiology exhibited neuronal progenitor numbers below the age average in controls. Virus infection with and without seizures significantly decreased the mean number of neuronal progenitor cells by 43% and 76% as compared to age-matched controls. Ki-67 labelling demonstrated that hippocampal cell proliferation was neither affected by infection nor by epilepsy of non-viral aetiology. Analysis of CDV infection in cells expressing caspase-3, doublecortin or Ki-67 indicated that infection of neuronal progenitor cells is extremely rare and suggests that infection might damage non-differentiated progenitor cells, hamper neuronal differentiation and promote glial differentiation. A high inter-individual variance in the number of lectin-reactive microglial cells was evident in dogs with distemper infection. Statistical analyses did not reveal a correlation between the number of lectin-reactive microglia cells and neuronal progenitor cells. Our data demonstrate that virus encephalitis with and without seizures can exert detrimental effects on hippocampal neurogenesis, which might contribute to long-term consequences of the disease. The lack of a significant impact of distemper virus on Ki-67-labelled cells indicates that the infection affected neuronal differentiation and

Evaluation and impact study of detriment caused by oil products on Shadegan wetland environment

International Nuclear Information System (INIS)

Esmaeili Sarri, A.; Emandel, K.; Kourgez, S.

2000-01-01

The international wetland of Shadegan with an area of 400 thousands hector is located in south of Khosestan which from south part is connected to Persian Gulf and correlated to it. During the oil-war in Persian Gulf region and discharging crude oil from Kuwait's oil wells into wetland of Shadegan, almost 20% of vegetation coverage in this wetland which is vital for livestock food without any cost, has been extensively damaged. Experts estimated that it takes about 10 years (1370-1380) to recovering the lost of vegetation coverage in this area. Economical evaluation base on effects of oil pollution on vegetation coverage in wetland of Shadegan has been studied by compensation trade upon cost and interest economical Technic. Price of barley as a provender given by governmental agencies to dairy farmers was used as a cost evaluation technic. As a first step, types of vegetation base on cost and quality of nutrient value were classified and then according to these classification, some coefficient for them were determined. By multiplying these coefficients to price of barley (as a dry-provender and best quality) related to year of 1370 until 1379, the money worth (in Rials) of each vegetation community was calculated. For actual economical determination lost of vegetation coverage in wetland of Shadegan it is necessary to multiplying amounts of vegetation lost for each community per year (in hector) to amounts of provender consumed by domestic animals (in ton), which this determines the quantity of vegetation and their types. then by multiplying these quantity to equivalent money worth (in Rials) which is related to amount of vegetation lost per year, will be the actual vegetation lost for each community per year

Deeply hidden inside introduced biogenic structures - Pacific oyster reefs reduce detrimental barnacle overgrowth on native blue mussels

Science.gov (United States)

Buschbaum, Christian; Cornelius, Annika; Goedknegt, M. Anouk

2016-11-01

In sedimentary coastal ecosystems shells of epibenthic organisms such as blue mussels (Mytilus edulis) provide the only major attachment surface for barnacle epibionts, which may cause detrimental effects on their mussel basibionts by e.g. reducing growth rate. In the European Wadden Sea, beds of native blue mussels have been invaded by Pacific oysters Crassostrea gigas, which transformed these beds into mixed reefs of oysters with mussels. In this study, we determined the spatial distribution of M. edulis and their barnacle epibionts (Semibalanus balanoides) within the reef matrix. Mean mussel density near the bottom was about twice as high compared to the mussel density near the top of an oyster reef, whereas barnacles on mussels showed a reversed pattern. Barnacle dry weight per mussel was on average 14 times higher near the top than at the bottom. This pattern was confirmed by experimentally placing clean M. edulis at the top and on the bottom of oyster reefs at two sites in the Wadden Sea (island of Texel, The Netherlands; island of Sylt, Germany). After an experimental period of five weeks (April and May 2015, the main settlement period of S. balanoides), the number of barnacles per mussel was at both sites significantly higher on mussels near the top compared to near the bottom. We conclude that the oyster reef matrix offers a refuge for M. edulis: inside reefs they are not only better protected against predators but also against detrimental barnacle overgrowth. This study shows that alien species can cause beneficial effects for native organisms and should not be generally considered as a risk for the recipient marine ecosystems.

Later maturation of the beneficial than the detrimental effect of selective memory retrieval.

Science.gov (United States)

Aslan, Alp; Bäuml, Karl-Heinz T

2014-04-01

In adults, selective memory retrieval can both impair and improve recall of other memories. The study reported here examined whether children also show these two faces of memory retrieval. Employing a variant of the directed-forgetting task, we asked second, fourth, and seventh graders to study a list of target and nontarget words. After study, the participants received a cue to either forget or continue remembering the list. We subsequently asked some participants to recall the nontarget words before we tested their memory for the target words; for the remaining participants, we tested memory only for the target words. Prior retrieval of nontarget words impaired retrieval of to-be-remembered target words, regardless of children's age. In contrast, prior retrieval of nontarget words improved recall of to-be-forgotten target words in seventh graders, though not in fourth and second graders. These results suggest a developmental dissociation between the two faces of memory retrieval and indicate later maturation of the beneficial effect than of the detrimental effect of selective memory retrieval.

Bioinformatics tools and database resources for systems genetics analysis in miceça short review and an evaluation of future needs

NARCIS (Netherlands)

Durrant, M.C.; Swertz, M.A.; Alberts, R.; Arends, D.; Möller, S.; Mott, R.; Prins, J.C.P.; Velde, van der K.J.; Jansen, R.C.; Schughart, K.

2012-01-01

During a meeting of the SYSGENET working group ‘Bioinformatics’, currently available software tools and databases for systems genetics in mice were reviewed and the needs for future developments discussed. The group evaluated interoperability and performed initial feasibility studies. To aid future

A methodology for the evaluation of collective doses arising from radioactive discharges to the atmosphere

International Nuclear Information System (INIS)

Hallam, J.; Linsley, G.S.

1980-01-01

The ICRP recommend the use of optimisation as a means of ensuring that the total detriment from any practice is appropriately small in relation to the benefit resulting from its introduction. The calculation of total health detriment requires the evaluation of the complete dose distribution throughout the irradiated population from all isotopes via all pathways. This paper describes methods for the evaluation of collective dose, which may be used in the assessment of detriment. The stages in the assessment of collective dose from an atmospheric release can be summarised as follows: (1) An atmospheric dispersion model is used to evaluate the spatial distribution of activity and thereby the dose to an individual from inhalation and external irradiation at any position with respect to the discharge point. (2) The UK population distribution on a 1 x 1 km grid is then used for the evaluation of collective dose from these pathways. (3) Foodchain models are used to estimate the radioactivity per unit mass in a range of different foodstuffs per unit deposition rate or surface deposit. (4) The distribution of agricultural practices in the UK on a 5 x 5 km grid, taken together with the atmospheric dispersion model allows the estimation of the total activity reaching man via food, and hence the collective dose. This combination of models and data arrays allows assessments to be made of the collective dose due to atmospheric releases of radioactive materials at any geographical location in the United Kingdom. (author)

Thrombophilia and assisted reproduction technology-any detrimental impact or unnecessary overuse?

Science.gov (United States)

Ata, Baris; Urman, Bulent

2016-10-01

The aim of this study is to provide an overview of the studies investigating a possible association between thrombophilia and assisted reproductive technology (ART) outcome. This is a literature review. Congenital thrombophilias (CoT) are reported to be associated with pregnancy loss. However, the association between CoT and early pregnancy loss is weak and does not necessarily support causation. CoT are more likely to be associated with late fetal loss. Even though data pooled from case-control and cohort studies suggest an increased risk of ART failure in women with CoTs, there seems no association when the analysis is confined to better quality cohort studies. The evidence supporting anticoagulation to improve ART outcome in CoT carriers is weak. Likewise, studies on antiphospholipid antibodies (APAs) and ART outcome suffer from multiple methodological limitations and a detrimental impact of APA positivity is controversial. Empirical administration of heparin or low molecular weight heparin to women with recurrent ART failures is supported by weak evidence. Importantly, thrombophilias are likely to increase thrombotic complications after ovarian stimulation for ART. Current evidence does not support routinely testing for or treatment of thrombophilia in the setting of ART nor in couples with implantation failure. A careful personal and family history should be obtained and a risk assessment for thrombotic complications should be made in every woman undergoing ovarian stimulation. If positive, testing for thrombophilia is warranted.

FutureGen Project Report

Energy Technology Data Exchange (ETDEWEB)

Cabe, Jim; Elliott, Mike

2010-09-30

This report summarizes the comprehensive siting, permitting, engineering, design, and costing activities completed by the FutureGen Industrial Alliance, the Department of Energy, and associated supporting subcontractors to develop a first of a kind near zero emissions integrated gasification combined cycle power plant and carbon capture and storage project (IGCC-CCS). With the goal to design, build, and reliably operate the first IGCC-CCS facility, FutureGen would have been the lowest emitting pulverized coal power plant in the world, while providing a timely and relevant basis for coal combustion power plants deploying carbon capture in the future. The content of this report summarizes key findings and results of applicable project evaluations; modeling, design, and engineering assessments; cost estimate reports; and schedule and risk mitigation from initiation of the FutureGen project through final flow sheet analyses including capital and operating reports completed under DOE award DE-FE0000587. This project report necessarily builds upon previously completed siting, design, and development work executed under DOE award DE-FC26- 06NT4207 which included the siting process; environmental permitting, compliance, and mitigation under the National Environmental Policy Act; and development of conceptual and design basis documentation for the FutureGen plant. For completeness, the report includes as attachments the siting and design basis documents, as well as the source documentation for the following: • Site evaluation and selection process and environmental characterization • Underground Injection Control (UIC) Permit Application including well design and subsurface modeling • FutureGen IGCC-CCS Design Basis Document • Process evaluations and technology selection via Illinois Clean Coal Review Board Technical Report • Process flow diagrams and heat/material balance for slurry-fed gasifier configuration • Process flow diagrams and heat/material balance

Cutting processes and their detrimental effects

International Nuclear Information System (INIS)

Pourprix, M.; Pilot, G.

1988-01-01

The cutting processes used actually for nuclear facilities dismantling are, for the most mechanic or thermic processes already widely tested in various industrial sectors. Some of there are still in faisability studies or in focus sed prototypes. By the criteria to take into account in the choice of such process, for future dismantlings, it is shown that the emitted nuisances should be wellknown and correctly overcome, in view to reduce the cutting process impact on its environment. In the second part we present the IPSN research. We describe the actual state of works realized in collaboration between French and European teams, especially on nuisances characterizations (gas, aerosols) and the means to confine it (ventilation, source collecting, filtration). In the end of this text we indicate the interest for the realization of intercomparison program and for qualification of various cutting processes taking into account the nuisances aspects in view to extrapolate results obtained in inactive situation at those obtained in real dismantling situations [fr

Evaluation of the applicability in the future climate of a statistical downscaling method in France

Science.gov (United States)

Dayon, G.; Boé, J.; Martin, E.

2013-12-01

The uncertainties in climate projections during the next decades generally remain large, with an important contribution of internal climate variability. To quantify and capture the impact of those uncertainties in impact projections, multi-model and multi-member approaches are essential. Statistical downscaling (SD) methods are computationally inexpensive allowing for large ensemble approaches. The main weakness of SD is that it relies on a stationarity hypothesis, namely that the statistical relation established in the present climate remains valid in the climate change context. In this study, the evaluation of SD methods developed for a future study of hydrological changes during the next decades over France is presented, focusing on precipitation. The SD methods are all based on the analogs method which is quite simple to set up and permits to easily test different combinations of predictors, the only changing parameter in the methods discussed in this presentation. The basic idea of the analogs method is that for a same large scale climatic state, the state of local variables will be identical. In a climate change context, the statistical relation established on past climate is assumed to remain valid in the future climate. In practice, this stationarity assumption is impossible to verify until the future climate is effectively observed. It is possible to evaluate the ability of SD methods to reproduce the interannual variability in the present climate, but this approach does not guarantee their validity in the future climate as the mechanisms that play in the interannual and climate change contexts may not be identical. Another common approach is to test whether a SD method is able to reproduce observed, as they may be partly caused by climate changes. The observed trends in precipitation are compared to those obtained by downscaling 4 different atmospheric reanalyses with analogs methods. The uncertainties in downscaled trends due to renalyses are very large

The Desired Image of the Future Economy of the Industrial Region: Development Trends and Evaluation Methodology

Directory of Open Access Journals (Sweden)

Olga Aleksandrovna Romanova

2017-09-01

Full Text Available In the article, the authors emphasize that industrial regions play an important role in the increasing of technological independence of Russia. We show that the decline in the share of processing industries in the gross regional product can not be treated as a negative de-industrialization of the economy. The article proves that the increase in the speed of changements, instability of socio-economic systems, the diverse risks predetermine the need to develop new methodological approaches to predictive research. The studies aimed at developing a technology for the design of the desired image of the future and the methodology for its evaluation are of high importance. For the initial stage of the research, the authors propose the methodological approach for assessing the desired image of the future of metallurgy as one of the most important industry of the region. We propose the term of «technological image of the regional metallurgy». We show that repositioning the image of the regional metallurgical complex is quite a long process. This have determined the need to define the stages of repositioning. The proposed methodology of the evaluation of desired future includes the methodological provisions to quantify the characteristics of goals achieved at the respective stages of the repositioning of the metallurgy. The methodological approach to the design of the desired image of the future implies the following stages: the identification of the priority areas of the technological development of regional metallurgy on the basis of bibliometric and patent analysis; the evaluation of dynamics of the development of the structure of metal products domestic consumption based on comparative analysis and relevant analytical methods as well as its forecasting; the design of the factor model, allowing to identify the parameters quantifying the technological image of the regional metallurgy based on the principal components method,; systematization of

Using Data Mining Techniques to Predict the Detriment Level of Car Insurance Customers

Directory of Open Access Journals (Sweden)

Seyyed Mahmood Izadparast

2012-07-01

Full Text Available Nowadays customers’ role is changed from just accepting the producers, to leading investors, producers, and even researchers and inventors. Therefore, it is necessary for organizations to identify their customers well and to make plans for them. Some statistical and machine-based learning methods are used so far. However these methods alone are not without limitations. Using various methods of data mining, this research was to eliminate those restrictions as far as possible, so that a framework for identification of car insurance customers could be provided. In fact, the purpose was to categorize the most similar customers and to estimate the amount of risk in each category, according to their characteristics. Now, using this scale (i.e. amount of risk in each category and considering the type of customer’s policy, the level of recompense could be estimated. This criterion can be helpful to identify customers and for making insurance tariff policies. For this purpose, in insurance industry the two data mining methods were been used to estimate customers’ detriment: the decision tree and clustering. Nevertheless, the decision tree method appears to give better results, although at the same, the clustering method generates a good categorization.

Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection.

Directory of Open Access Journals (Sweden)

Fredric Carlsson

2010-05-01

Full Text Available The Esx-1 (type VII secretion system is a major virulence determinant of pathogenic mycobacteria, including Mycobacterium marinum. However, the molecular events and host-pathogen interactions underlying Esx-1-mediated virulence in vivo remain unclear. Here we address this problem in a non-lethal mouse model of M. marinum infection that allows detailed quantitative analysis of disease progression. M. marinum established local infection in mouse tails, with Esx-1-dependent formation of caseating granulomas similar to those formed in human tuberculosis, and bone deterioration reminiscent of skeletal tuberculosis. Analysis of tails infected with wild type or Esx-1-deficient bacteria showed that Esx-1 enhanced generation of proinflammatory cytokines, including the secreted form of IL-1beta, suggesting that Esx-1 promotes inflammasome activation in vivo. In vitro experiments indicated that Esx-1-dependent inflammasome activation required the host NLRP3 and ASC proteins. Infection of wild type and ASC-deficient mice demonstrated that Esx-1-dependent inflammasome activation exacerbated disease without restricting bacterial growth, indicating a host-detrimental role of this inflammatory pathway in mycobacterial infection. These findings define an immunoregulatory role for Esx-1 in a specific host-pathogen interaction in vivo, and indicate that the Esx-1 secretion system promotes disease and inflammation through its ability to activate the inflammasome.

Exercise following a short immobilization period is detrimental to tendon properties and joint mechanics in a rat rotator cuff injury model.

Science.gov (United States)

Peltz, Cathryn D; Sarver, Joseph J; Dourte, Leann M; Würgler-Hauri, Carola C; Williams, Gerald R; Soslowsky, Louis J

2010-07-01

Rotator cuff tears are a common clinical problem that can result in pain and disability. Previous studies in a rat model showed enhanced tendon to bone healing with postoperative immobilization. The objective of this study was to determine the effect of postimmobilization activity level on insertion site properties and joint mechanics in a rat model. Our hypothesis was that exercise following a short period of immobilization will cause detrimental changes in insertion site properties compared to cage activity following the same period of immobilization, but that passive shoulder mechanics will not be affected. We detached and repaired the supraspinatus tendon of 22 Sprague-Dawley rats, and the injured shoulder was immobilized postoperatively for 2 weeks. Following immobilization, rats were prescribed cage activity or exercise for 12 weeks. Passive shoulder mechanics were determined, and following euthanasia, tendon cross-sectional area and mechanical properties were measured. Exercise following immobilization resulted in significant decreases compared to cage activity in range of motion, tendon stiffness, modulus, percent relaxation, and several parameters from both a structurally based elastic model and a quasi-linear viscoelastic model. Therefore, we conclude that after a short period of immobilization, increased activity is detrimental to both tendon mechanical properties and shoulder joint mechanics, presumably due to increased scar production. (c) 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc

Type I interferon induction is detrimental during infection with the Whipple's disease bacterium, Tropheryma whipplei.

Directory of Open Access Journals (Sweden)

Khatoun Al Moussawi

2010-01-01

Full Text Available Macrophages are the first line of defense against pathogens. Upon infection macrophages usually produce high levels of proinflammatory mediators. However, macrophages can undergo an alternate polarization leading to a permissive state. In assessing global macrophage responses to the bacterial agent of Whipple's disease, Tropheryma whipplei, we found that T. whipplei induced M2 macrophage polarization which was compatible with bacterial replication. Surprisingly, this M2 polarization of infected macrophages was associated with apoptosis induction and a functional type I interferon (IFN response, through IRF3 activation and STAT1 phosphorylation. Using macrophages from mice deficient for the type I IFN receptor, we found that this type I IFN response was required for T. whipplei-induced macrophage apoptosis in a JNK-dependent manner and was associated with the intracellular replication of T. whipplei independently of JNK. This study underscores the role of macrophage polarization in host responses and highlights the detrimental role of type I IFN during T. whipplei infection.

Ethicted (evaluation process model to improve personalised ICT services for independent living and active ageing)--future scenario.

Science.gov (United States)

Kärki, Anne; Sävel, Jaana; Sallinen, Merja; Kuusinen, Jere

2013-01-01

ICT innovations are constantly developed, and there is no lack of elderly customers, as the number of the elderly is dramatically increasing. Elderly are willing to use ICT to increase their own safety and social activity, but they need trust on the reliability, accessibility and other ethical aspects of ICT including the maintenance of privacy and self-determination. Ethical standards for ICT are usually not considered. "Ethicted" characterizes an ICT service or product as ethically evaluated. As a standardized procedure, it will not only increase the acceptability of ICT, but also provide services for ICT developers. In the future scenario, ICT under development should be evaluated by using a process model that is specifically built to find the lacks in ethical aspects. The model would then be tested by end-users, the formal and informal care givers, to receive direct feedback for redeveloping solutions. As final outcomes, there should be standards for ICT in elderly care and a service for ICT developers to utilize the evaluation model. This future scenario work included partners from 6 EU member countries. The combination of academic research and industrial/commercial interest of ICT developers should and can bring new value to assistive ICT for elderly care.

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke.

Science.gov (United States)

Gelderblom, Mathias; Melzer, Nico; Schattling, Benjamin; Göb, Eva; Hicking, Gordon; Arunachalam, Priyadharshini; Bittner, Stefan; Ufer, Friederike; Herrmann, Alexander M; Bernreuther, Christian; Glatzel, Markus; Gerloff, Christian; Kleinschnitz, Christoph; Meuth, Sven G; Friese, Manuel A; Magnus, Tim

2014-11-01

Brain injury during stroke results in oxidative stress and the release of factors that include extracellular Ca(2+), hydrogen peroxide, adenosine diphosphate ribose, and nicotinic acid adenine dinucleotide phosphate. These alterations of the extracellular milieu change the activity of transient receptor potential melastatin subfamily member 2 (TRPM2), a nonselective cation channel expressed in the central nervous system and the immune system. Our goal was to evaluate the contribution of TRPM2 to the tissue damage after stroke. In accordance with current quality guidelines, we independently characterized Trpm2 in a murine ischemic stroke model in 2 different laboratories. Gene deficiency of Trpm2 resulted in significantly improved neurological outcome and decreased infarct size. Besides an already known moderate neuroprotective effect of Trpm2 deficiency in vitro, ischemic brain invasion by neutrophils and macrophages was particularly reduced in Trpm2-deficient mice. Bone marrow chimeric mice revealed that Trpm2 deficiency in the peripheral immune system is responsible for the protective phenotype. Furthermore, experiments with mixed bone marrow chimeras demonstrated that Trpm2 is essential for the migration of neutrophils and, to a lesser extent, also of macrophages into ischemic hemispheres. Notably, the pharmacological TRPM2 inhibitor, N-(p-amylcinnamoyl)anthranilic acid, was equally protective in the stroke model. Although a neuroprotective effect of TRPM2 in vitro is well known, we can show for the first time that the detrimental role of TRPM2 in stroke primarily depends on its role in activating peripheral immune cells. Targeting TRPM2 systemically represents a promising therapeutic approach for ischemic stroke. © 2014 American Heart Association, Inc.

Detrimental and protective fat: body fat distribution and its relation to metabolic disease.

Science.gov (United States)

Booth, Andrea; Magnuson, Aaron; Foster, Michelle

2014-01-01

Obesity is linked to numerous comorbidities that include, but are not limited to, glucose intolerance, insulin resistance, dyslipidemia, and cardiovascular disease. Current evidence suggests, however, obesity itself is not an exclusive predictor of metabolic dysregulation but rather adipose tissue distribution. Obesity-related adverse health consequences occur predominately in individuals with upper body fat accumulation, the detrimental distribution, commonly associated with visceral obesity. Increased lower body subcutaneous adipose tissue, however, is associated with a reduced risk of obesity-induced metabolic dysregulation and even enhanced insulin sensitivity, thus, storage in this region is considered protective. The proposed mechanisms that causally relate the differential outcomes of adipose tissue distribution are often attributed to location and/or adipocyte regulation. Visceral adipose tissue effluent to the portal vein drains into the liver where hepatocytes are directly exposed to its metabolites and secretory products, whereas the subcutaneous adipose tissue drains systemically. Adipose depots are also inherently different in numerous ways such as adipokine release, immunity response and regulation, lipid turnover, rate of cell growth and death, and response to stress and sex hormones. Proximal extrinsic factors also play a role in the differential drive between adipose tissue depots. This review focuses on the deleterious mechanisms postulated to drive the differential metabolic response between central and lower body adipose tissue distribution.

Current and future standards in evaluation of erectile dysfunction

Directory of Open Access Journals (Sweden)

Raymond W Pak

2006-01-01

Full Text Available Sexual dysfunction and more specifically erectile dysfunction (ED can be a harbinger of serious occult medical conditions. ED can be considered a clinical manifestation of generalized vascular disease and therefore shares similar risk factors: aging, hypertension, diabetes mellitus, hypercholesterolemia and smoking. The initial evaluation of men with ED should be thorough. Studies of normal and abnormal penile tumescence have led to the discovery of many important pathways. The greatest medical advance in the management of male sexual dysfunction since the identification of androgens have been the discoveries that nitric oxide (NO is the primary neuro-modulator of penile smooth muscle relaxation and that oral phosphodiesterase type 5 inhibitors enhance erection quality through the NO mechanism. As a consequence of oral pharmacotherapies, the role of invasive diagnostics has diminished. Most guidelines recommend only history, physical exam and limited laboratory testing prior to instituting oral therapies for ED. In 2006 we still have unanswered questions about ED and these will frame the role of future diagnosis and therapy: can lifestyle changes alone improve erectile function; is ED a marker for the development of atherosclerotic heart disease, do lower urinary tract symptoms of benign prostatic hypertrophy and ED share a common pathway?

Mobile energy sharing futures

DEFF Research Database (Denmark)

Worgan, Paul; Knibbe, Jarrod; Plasencia, Diego Martinez

2016-01-01

We foresee a future where energy in our mobile devices can be shared and redistributed to suit our current task needs. Many of us are beginning to carry multiple mobile devices and we seek to re-evaluate the traditional view of a mobile device as only accepting energy. In our vision, we can...... sharing futures....

Detrimental effects of gum chewing on vigilance in children with attention deficit hyperactivity disorder.

Science.gov (United States)

Tucha, Lara; Simpson, William; Evans, Lynsay; Birrel, Laura; Sontag, Thomas A; Lange, Klaus W; Tucha, Oliver

2010-12-01

Impairments of attention are cardinal features of attention deficit hyperactivity disorder (ADHD) and can seriously affect the daily life of children with ADHD. Despite effective treatment strategies, there is a need of further treatment options that can be added to available and well established treatments. Further treatment options are needed since available treatments are often time consuming, expensive and limited regarding their external validity. Recent research demonstrated that gum chewing has beneficial effects on cognition including certain aspects of attention. Therefore, gum chewing may benefit children with ADHD in situations requiring particular cognitive efforts. In a crossover study, attentional functioning of 32 children with ADHD and 32 children without the condition was examined. All participants were assessed with chewing gum and without chewing gum. A computerized test was used for the assessment of vigilance and sustained attention. The findings of the present study suggest that gum chewing during task execution has detrimental effects on vigilance of both healthy children and children with ADHD. Sustained attention was not affected by gum chewing. Chewing gum, therefore, appears not to improve attentional performance in children with ADHD. Copyright © 2010 Elsevier Ltd. All rights reserved.

Current status and future directions of development of PR/PP evaluation methodology

International Nuclear Information System (INIS)

Kim, D. Y.; Kwon, E. H.; Kim, H. D.

2012-01-01

A mandatory design requirement for the introduction of generation IV nuclear energy systems (NESs) is defined as the characteristic of a nuclear energy system that impedes the diversion or undeclared production of nuclear material, or misuse of technology, by State in order to acquire nuclear weapons or other nuclear explosive devices. The same report also defines physical protection (PP) as the use of technical, administrative, and operational measures to prevent the theft of nuclear/radioactive material for the purpose of producing nuclear weapons, producing nuclear devices for nuclear terrorism, or using the facility or transportation system for radiological sabotage. Since the early 1970s right after the Indian nuclear test, the international community has recognized the limits of political and diplomatic means to prevent overt proliferation by states and looked for ways to incorporate technical features that are inherent in NESs. As a first step, active research has been conducted to develop a methodology to evaluate PR and PP components of NESs and has now been reduced to two main R and D streams: the Generation IV International Forum (GIF) and International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). (Currently, GIF and INPRO are leading the debate as major projects for PR and PP evaluation methods.) This paper presents an overview of the R and D accomplishments during the development of PR and PP evaluation methodology. It also suggests some directions for future research

Current status and future directions of development of PR/PP evaluation methodology

Energy Technology Data Exchange (ETDEWEB)

Kim, D. Y.; Kwon, E. H.; Kim, H. D. [KAERI, Daejeon (Korea, Republic of)

2012-10-15

A mandatory design requirement for the introduction of generation IV nuclear energy systems (NESs) is defined as the characteristic of a nuclear energy system that impedes the diversion or undeclared production of nuclear material, or misuse of technology, by State in order to acquire nuclear weapons or other nuclear explosive devices. The same report also defines physical protection (PP) as the use of technical, administrative, and operational measures to prevent the theft of nuclear/radioactive material for the purpose of producing nuclear weapons, producing nuclear devices for nuclear terrorism, or using the facility or transportation system for radiological sabotage. Since the early 1970s right after the Indian nuclear test, the international community has recognized the limits of political and diplomatic means to prevent overt proliferation by states and looked for ways to incorporate technical features that are inherent in NESs. As a first step, active research has been conducted to develop a methodology to evaluate PR and PP components of NESs and has now been reduced to two main R and D streams: the Generation IV International Forum (GIF) and International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). (Currently, GIF and INPRO are leading the debate as major projects for PR and PP evaluation methods.) This paper presents an overview of the R and D accomplishments during the development of PR and PP evaluation methodology. It also suggests some directions for future research.

Criteria of evaluation of success of future music masters on discipline «Physical education» in higher educational establishments

Directory of Open Access Journals (Sweden)

Demina Z.G.

2010-01-01

Full Text Available Traditional physical education program is not able to take into account the peculiarities of training and professional activity of students of musical and pedagogical professions, the more there is no universally accepted standards of form and final evaluation of the success of students in higher educational institutions of this discipline. In the article brought a modular curriculum structure of the discipline "Physical education" of future music teachers, and describes criteria for diagnosis of individual academic achievements of students - of future music teachers by point system..

Process evaluations in neurological rehabilitation: a mixed-evidence systematic review and recommendations for future research.

Science.gov (United States)

Masterson-Algar, Patricia; Burton, Christopher R; Rycroft-Malone, Jo

2016-11-08

To systematically review how process evaluations are currently designed, what methodologies are used and how are they developed alongside or within neurological rehabilitation trials. This mixed-methods systematic review had two evidence streams: stream I, studies reporting process evaluations alongside neurorehabilitation trials research and stream II, methodological guidance on process evaluation design and methodology. A search strategy was designed for each evidence stream. Data regarding process evaluation core concepts and design issues were extracted using a bespoke template. Evidence from both streams was analysed separately and then synthesised in a final overarching synthesis proposing a number of recommendations for future research. A total of 124 process evaluation studies, reporting on 106 interventions, were included in stream I evidence. 30 studies were included as stream II evidence. Synthesis 1 produced 9 themes, and synthesis 2 identified a total of 8 recommendations for process evaluation research. The overall synthesis resulted in 57 'synthesis recommendations' about process evaluation methodology grouped into 9 research areas, including the use of theory, the investigation of context, intervention staff characteristics and the delivery of the trial intervention. There remains no consensus regarding process evaluation terminology within the neurological rehabilitation field. There is a need for process evaluations to address the nature and influence of context over time. Process evaluations should clearly describe what intervention staff bring to a trial, including skills and experience prior to joining the research. Process evaluations should monitor intervention staff's learning effects and the possible impact that these may have on trial outcomes. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Evaluation of (+)-sparteine-like diamines for asymmetric synthesis.

Science.gov (United States)

Dearden, Michael J; McGrath, Matthew J; O'Brien, Peter

2004-08-20

Three new (+)-sparteine-like diamines were prepared from (-)-cytisine and evaluated as sparteine surrogates in the alpha-lithiation rearrangement of cyclooctene oxide and the palladium(II)/diamine catalyzed oxidative kinetic resolution of 1-indanol. The new diamines exhibited opposite enantioselectivity to that observed with (-)-sparteine but increasing the steric hindrance of the N-alkyl group beyond N-Et had a detrimental effect on enantioselectivity. The optimal N-Me diamine was evaluated with much success in five other (-)-sparteine-mediated processes involving different metals (lithium, magnesium, and copper) and different types of reaction mechanisms. Copyright 2004 American Chemical Society

A European Perspective on Auditory Processing Disorder-Current Knowledge and Future Research Focus

DEFF Research Database (Denmark)

IIiadou, Vasiliki; Ptok, Martin; Grech, Helen

2017-01-01

Current notions of "hearing impairment," as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing difficulties in everyday life that are indexed by reduced performance in other...... of diseases as H93.25 and in the forthcoming beta eleventh version. APDs may have detrimental effects on the affected individual, with low esteem, anxiety, and depression, and symptoms may remain into adulthood. These disorders may interfere with learning per se and with communication, social, emotional......, and academic-work aspects of life. The objective of the present paper is to define a baseline European APD consensus formulated by experienced clinicians and researchers in this specific field of human auditory science. A secondary aim is to identify issues that future research needs to address in order...

An Experimental Evaluation of Competing Age-Predictions of Future Time Perspective between Workplace and Retirement Domains.

Science.gov (United States)

Kerry, Matthew J; Embretson, Susan E

2017-01-01

Future time perspective (FTP) is defined as "perceptions of the future as being limited or open-ended" (Lang and Carstensen, 2002; p. 125). The construct figures prominently in both workplace and retirement domains, but the age-predictions are competing: Workplace research predicts decreasing FTP age-change, in contrast, retirement scholars predict increasing FTP age-change. For the first time, these competing predictions are pitted in an experimental manipulation of subjective life expectancy (SLE). A sample of N = 207 older adults (age 45-60) working full-time (>30-h/week) were randomly assigned to SLE questions framed as either 'Live-to' or 'Die-by' to evaluate competing predictions for FTP. Results indicate general support for decreasing age-change in FTP, indicated by independent-sample t -tests showing lower FTP in the 'Die-by' framing condition. Further general-linear model analyses were conducted to test for interaction effects of retirement planning with experimental framings on FTP and intended retirement; While retirement planning buffered FTP's decrease, simple-effects also revealed that retirement planning increased intentions for sooner retirement, but lack of planning increased intentions for later retirement. Discussion centers on practical implications of our findings and consequences validity evidence in future empirical research of FTP in both workplace and retirement domains.

Economic Evaluation of the Juvenile Drug Court/Reclaiming Futures (JDC/RF) Model.

Science.gov (United States)

McCollister, Kathryn; Baumer, Pamela; Davis, Monica; Greene, Alison; Stevens, Sally; Dennis, Michael

2018-07-01

Juvenile drug court (JDC) programs are an increasingly popular option for rehabilitating juvenile offenders with substance problems, but research has found inconsistent evidence regarding their effectiveness and economic impact. While assessing client outcomes such as reduced substance use and delinquency is necessary to gauge program effectiveness, a more comprehensive understanding of program success and sustainability can be attained by examining program costs and economic benefits. As part of the National Cross-Site Evaluation of JDC and Reclaiming Futures (RF), an economic analysis of five JDC/RF programs was conducted from a multisystem and multiagency perspective. The study highlights the direct and indirect costs of JDC/RF and the savings generated from reduced health problems, illegal activity, and missed school days. Results include the average (per participant) cost of JDC/RF, the total economic benefits per JDC/RF participant, and the net savings of JDC/RF relative to standard JDC.

“We Need more Practice!” How Future Teachers Evaluate Their Experiences with Micro-Teaching?

Directory of Open Access Journals (Sweden)

Andreja Retelj

2016-12-01

Full Text Available This paper deals with micro-teaching as a possibility for combining theory and practice during the studies of future teachers of German. One of the key elements for combining theory and practice is pedagogical practicums in primary and secondary schools. From students’ reflections on their practicums, we have seen that it is very difficult for students to put their theoretical knowledge into practice. In order to alleviate initial difficulties and the anxiety future teachers face, we have implemented a specific micro-teaching model at the Department of German, Dutch and Swedish; students in the second year of the MA-level pedagogical stream participated in the model. The students’ self-evaluation on the effects of micro-learning showed it to be a useful model for obtaining their first pedagogical experience because it allows students, through reflection and feedback from their didactics teachers and from their fellow students, to become aware of the didactic and methodological principles of modern foreign language teaching and thus to be better prepared for their teaching practicums.

Detrimental effects of workplace bullying: impediment of self-management competence via psychological distress

Directory of Open Access Journals (Sweden)

Gabriele eGiorgi

2016-02-01

Full Text Available Emotional intelligence has been linked to various positive outcomes, such as organizational effectiveness, commitment, morale and health. In addition, longitudinal studies demonstrate that the competencies of emotional intelligence may change and be developed over time. Researchers have argued that work relationships are important for the development of emotional competence, but their usefulness depends on the quality of the relationship. Workplace bullying is considered to be one of the most stressful phenomena in the workplace and an example of a dysfunctional and toxic relationship that has detrimental effects on an individual’s physical and psychological health. Hence, the objective of the present study was to analyze the relationship linking workplace bullying, psychological distress and the self-management competence of emotional intelligence. More specifically, we tested part of the model presented by Cherniss and Goleman (2001 in which researchers argued that individual emotional intelligence is a result of relationships at work. In addition, we extended the model by proposing that the relationship between exposure to workplace bullying and the competence of self-management is explained by psychological distress. Data analysis of 326 participants from two private sector organizations in Italy demonstrated that psychological distress fully mediated the relationship between workplace bullying and the emotional intelligence ability of self-management. The present study’s findings point to the idea that, not only may emotional intelligence assist in handling exposure to workplace bullying, but exposure to workplace bullying may impede emotional intelligence via psychological distress.

Detrimental Effects of Workplace Bullying: Impediment of Self-Management Competence via Psychological Distress

Science.gov (United States)

Giorgi, Gabriele; Perminienė, Milda; Montani, Francesco; Fiz-Perez, Javier; Mucci, Nicola; Arcangeli, Giulio

2016-01-01

Emotional intelligence has been linked to various positive outcomes, such as organizational effectiveness, commitment, morale, and health. In addition, longitudinal studies demonstrate that the competencies of emotional intelligence may change and be developed over time. Researchers have argued that work relationships are important for the development of emotional competence, but their usefulness depends on the quality of the relationship. Workplace bullying is considered to be one of the most stressful phenomena in the workplace and an example of a dysfunctional and toxic relationship that has detrimental effects on an individual’s physical and psychological health. Hence, the objective of the present study was to analyze the relationship linking workplace bullying, psychological distress and the self-management competence of emotional intelligence. More specifically, we tested part of the model presented by Cherniss and Goleman (2001) in which researchers argued that individual emotional intelligence is a result of relationships at work. In addition, we extended the model by proposing that the relationship between exposure to workplace bullying and the competence of self-management is explained by psychological distress. Data analysis of 326 participants from two private sector organizations in Italy demonstrated that psychological distress fully mediated the relationship between workplace bullying and the emotional intelligence ability of self-management. The present study’s findings point to the idea that, not only may emotional intelligence assist in handling exposure to workplace bullying, but exposure to workplace bullying may impede emotional intelligence via psychological distress. PMID:26913013

Life Goals and Well-Being: Are Extrinsic Aspirations Always Detrimental to Well-Being?

Directory of Open Access Journals (Sweden)

Ingrid Brdar

2009-12-01

Full Text Available Past research has revealed that relative importance a person places on extrinsic life goals as oposed to intrinsic ones is related to lower well-being. But sometimes it is more important why a goal is being pursued than the content of the goal. Materialistic aspirations will not decrease people's well-being if they help them to achieve basic financial security or some intrinsic goals. On the other hand, if social comparison or seeking power drives extrinsic orientation, these aspirations may be detrimental for well-being, since they do not satisfy satisfy our basic psychological needs. Research from Croatia and other, less rich countries suggest that extrinsic aspirations are not necessarily deterimental but may even contribute to well-being. This finding suggests that various factors can moderate the relationship between aspirations and well-being. Intrinsic life goals may probably be affordable only for people who are well off enough. The meaning of financial success in transitional and poor countries may not necesseraly be associated with purchase and consumption. On the contrary, it may bring opportunities and possibilities of self-expression and self-growth. Individualistic societies allow individuals to pursue their intrinsic goals while collectivistic cultures stress extrinsic ones. Although this extrinsic orientation may detract their well-being, the sense of individual well-being may not be as important to them as the survival of the group they belong to or so called social well-being.

Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health.

Science.gov (United States)

Zhang, Ning; Valentine, Joseph M; Zhou, You; Li, Mengyao E; Zhang, Yiqiang; Bhattacharya, Arunabh; Walsh, Michael E; Fischer, Katherine E; Austad, Steven N; Osmulski, Pawel; Gaczynska, Maria; Shoelson, Steven E; Van Remmen, Holly; Chen, Hung I; Chen, Yidong; Liang, Hanyu; Musi, Nicolas

2017-08-01

Older adults universally suffer from sarcopenia and approximately 60-70% are diabetic or prediabetic. Nonetheless, the mechanisms underlying these aging-related metabolic disorders are unknown. NFκB has been implicated in the pathogenesis of several aging-related pathologies including sarcopenia and type 2 diabetes and has been proposed as a target against them. NFκB also is thought to mediate muscle wasting seen with disuse, denervation, and some systemic diseases (e.g., cancer, sepsis). We tested the hypothesis that lifelong inhibition of the classical NFκB pathway would protect against aging-related sarcopenia and insulin resistance. Aged mice with muscle-specific overexpression of a super-repressor IκBα mutant (MISR) were protected from insulin resistance. However, MISR mice were not protected from sarcopenia; to the contrary, these mice had decreases in muscle mass and strength compared to wild-type mice. In MISR mice, NFκB suppression also led to an increase in proteasome activity and alterations in several genes and pathways involved in muscle growth and atrophy (e.g., myostatin). We conclude that the mechanism behind aging-induced sarcopenia is NFκB independent and differs from muscle wasting due to pathologic conditions. Our findings also indicate that, while suppressing NFκB improves insulin sensitivity in aged mice, this transcription factor is important for normal muscle mass maintenance and its sustained inhibition is detrimental to muscle function. © 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Corrosion evaluation of cooling-water treatments for gas centrifuge facilities

International Nuclear Information System (INIS)

Schmidt, C.R.; Meredith, P.F.

1980-01-01

The corrosion resistance of six different types of weighted metal coupons was evaluated at 29 0 C (84 0 F) in flowing water containing nitrite-borate-silicate corrosion inhibitors. The question for evaluation was whether it would be more advantageous: (1) to drain the treated cooling water from the centrifuge machine and to expose them to moisture-laden air over an assumed shop downtime and repair perid of 1 month; or (2) to let the treated cooling water remain stagnant in the machines during this downtime. The moisture-laden-air exposure was more detrimental

Robot Futures

DEFF Research Database (Denmark)

Christoffersen, Anja; Grindsted Nielsen, Sally; Jochum, Elizabeth Ann

Robots are increasingly used in health care settings, e.g., as homecare assistants and personal companions. One challenge for personal robots in the home is acceptance. We describe an innovative approach to influencing the acceptance of care robots using theatrical performance. Live performance...... is a useful testbed for developing and evaluating what makes robots expressive; it is also a useful platform for designing robot behaviors and dialogue that result in believable characters. Therefore theatre is a valuable testbed for studying human-robot interaction (HRI). We investigate how audiences...... perceive social robots interacting with humans in a future care scenario through a scripted performance. We discuss our methods and initial findings, and outline future work....

Non-human primates avoid the detrimental effects of prenatal androgen exposure in mixed-sex litters: combined demographic, behavioral, and genetic analyses.

Science.gov (United States)

Bradley, Brenda J; Snowdon, Charles T; McGrew, William C; Lawler, Richard R; Guevara, Elaine E; McIntosh, Annick; O'Connor, Timothy

2016-12-01

Producing single versus multiple births has important life history trade-offs, including the potential benefits and risks of sharing a common in utero environment. Sex hormones can diffuse through amniotic fluid and fetal membranes, and females with male littermates risk exposure to high levels of fetal testosterone, which are shown to have masculinizing effects and negative fitness consequences in many mammals. Whereas most primates give birth to single offspring, several New World monkey and strepsirrhine species regularly give birth to small litters. We examined whether neonatal testosterone exposure might be detrimental to females in mixed-sex litters by compiling data from long-term breeding records for seven primate species (Saguinus oedipus; Varecia variegata, Varecia rubra, Microcebus murinis, Mirza coquereli, Cheirogaleus medius, Galago moholi). Litter sex ratios did not differ from the expected 1:2:1 (MM:MF:FF for twins) and 1:2:2:1 (MMM:MMF:MFF:FFF for triplets). Measures of reproductive success, including female survivorship, offspring-survivorship, and inter-birth interval, did not differ between females born in mixed-sex versus all-female litters, indicating that litter-producing non-human primates, unlike humans and rodents, show no signs of detrimental effects from androgen exposure in mixed sex litters. Although we found no evidence for CYP19A1 gene duplications-a hypothesized mechanism for coping with androgen exposure-aromatase protein evolution shows patterns of convergence among litter-producing taxa. That some primates have effectively found a way to circumvent a major cost of multiple births has implications for understanding variation in litter size and life history strategies across mammals. © 2016 Wiley Periodicals, Inc.

Anticipating our future robot society : The evaluation of future robot applications from a user's perspective

NARCIS (Netherlands)

de Graaf, M.M.A.; Ben Allouch, Soumaya

2016-01-01

With an expected growth of robots in our future society, we believe that potential implications for robot applications should be addressed. Therefore, we conducted an online questionnaire among the general Dutch population (n= 1162) to map the societal impact of robots by identifying potential

Visual soil evaluation - future research requirements

Science.gov (United States)

Emmet-Booth, Jeremy; Forristal, Dermot; Fenton, Owen; Ball, Bruce; Holden, Nick

2017-04-01

A review of Visual Soil Evaluation (VSE) techniques (Emmet-Booth et al., 2016) highlighted their established utility for soil quality assessment, though some limitations were identified; (1) The examination of aggregate size, visible intra-porosity and shape forms a key assessment criterion in almost all methods, thus limiting evaluation to structural form. The addition of criteria that holistically examine structure may be desirable. For example, structural stability can be indicated using dispersion tests or examining soil surface crusting, while the assessment of soil colour may indirectly indicate soil organic matter content, a contributor to stability. Organic matter assessment may also indicate structural resilience, along with rooting, earthworm numbers or shrinkage cracking. (2) Soil texture may influence results or impeded method deployment. Modification of procedures to account for extreme texture variation is desirable. For example, evidence of compaction in sandy or single grain soils greatly differs to that in clayey soils. Some procedures incorporate separate classification systems or adjust deployment based on texture. (3) Research into impacts of soil moisture content on VSE evaluation criteria is required. Criteria such as rupture resistance and shape may be affected by moisture content. It is generally recommended that methods are deployed on moist soils and quantification of influences of moisture variation on results is necessary. (4) Robust sampling strategies for method deployment are required. Dealing with spatial variation differs between methods, but where methods can be deployed over large areas, clear instruction on sampling is required. Additionally, as emphasis has been placed on the agricultural production of soil, so the ability of VSE for exploring structural quality in terms of carbon storage, water purification and biodiversity support also requires research. References Emmet-Booth, J.P., Forristal. P.D., Fenton, O., Ball, B

Literature investigation into radiation effects in rock salt. Evaluation of Russian literature

International Nuclear Information System (INIS)

Schneider, L.; Herzog, C.; Krause, H.; Liebscher, B.

1994-01-01

A total of 121 published and unpublished papers was evaluated. In the field of radiation induced defect formation of alkali halide crystals, Russian research institutes have performed manifold studies. Above all expansive basic research was carried out. The same refers to the use of natural rock salt for this type of studies. The majority of the activities are of a basic character and designed to achieve understanding of subprocesses, and therefore they concentrated mainly on monocrystals and on synthetic NaCl crystals doped with anionic or cationic additives. During the studies the influence factors which are most important for radiation detriment, such as type of radiation, irradiation temperature and contamination degree, varied, and different temperature influences after irradiation were considered. The results achieved give information on radiation detriment, kinetics, and on the efficiency of the respective influence factor. (orig.) [de

Evaluation of cancer detection efficiency by means of hybrid and inverse filter in chest radiography

International Nuclear Information System (INIS)

Kim, Youn Young; Kim, Tae Young; Kim, Hyun Ji; Kim, Jung Min; Park, Min Seock

2013-01-01

The purpose of this study is to evaluate usefulness of Hybrid image and Inverse image about detection of tumor shadow in chest radiography using ROC analysis. Original images of 60 cases are selected from Standards digital image date base issued by the Japanese Society of Radiological Technology. Through computer language of C, Inverse images of 60 cases and Hybrid image of 30 cases are made. The continues reading experiment was conducted. In the case of inverse image were observed by 5 radiographer and 2 radiologist. In the case of In case of Hybrid image were observed by 3 student radiographer and 2 experienced radiographer. ROC curve are constructed using ROCKIT Program made by Metz. In Inverse image, a Az of average ROC curve was increases from 0.742 of original image to 0.775 of inverse image. In normal cases, the effect of the detrimental is same to that of the beneficial, however In abnormal cases, the beneficial effect is greater than detrimental effect. However in Hybrid image, a Az of average ROC curve was decreases from 0.5253 of original image to 0.4868 of Hybrid image. In Normal cases, the effect of the detrimental is greater than that of the Beneficial, however In abnormal cases, the Beneficial effect is greater than detrimental effect. The inverse image can be more positively considered for the detecting of tumor than the hybrid image

Neural and personality correlates of individual differences related to the effects of acute tryptophan depletion on future reward evaluation.

Science.gov (United States)

Demoto, Yoshihiko; Okada, Go; Okamoto, Yasumasa; Kunisato, Yoshihiko; Aoyama, Shiori; Onoda, Keiichi; Munakata, Ayumi; Nomura, Michio; Tanaka, Saori C; Schweighofer, Nicolas; Doya, Kenji; Yamawaki, Shigeto

2012-01-01

In general, humans tend to discount the value of delayed reward. An increase in the rate of discounting leads to an inability to select a delayed reward over a smaller immediate reward (reward-delay impulsivity). Although deficits in the serotonergic system are implicated in this reward-delay impulsivity, there is individual variation in response to serotonin depletion. The aim of the present study was to investigate whether the effects of serotonin depletion on the ability to evaluate future reward are affected by individual personality traits or brain activation. Personality traits were assessed using the NEO-Five Factor Inventory and Temperament and Character Inventory. The central serotonergic levels of 16 healthy volunteers were manipulated by dietary tryptophan depletion. Subjects performed a delayed reward choice task that required the continuous estimation of reward value during functional magnetic resonance imaging scanning. Discounting rates were increased in 9 participants, but were unchanged or decreased in 7 participants in response to tryptophan depletion. Participants whose discounting rate was increased by tryptophan depletion had significantly higher neuroticism and lower self-directedness. Furthermore, tryptophan depletion differentially affected the groups in terms of hemodynamic responses to the value of predicted future reward in the right insula. These results suggest that individuals who have high neuroticism and low self-directedness as personality traits are particularly vulnerable to the effect of low serotonin on future reward evaluation accompanied by altered brain activation patterns. Copyright © 2012 S. Karger AG, Basel.

Not my future? Core values and the neural representation of future events.

Science.gov (United States)

Brosch, Tobias; Stussi, Yoann; Desrichard, Olivier; Sander, David

2018-06-01

Individuals with pronounced self-transcendence values have been shown to put greater weight on the long-term consequences of their actions when making decisions. Using functional magnetic resonance imaging, we investigated the neural mechanisms underlying the evaluation of events occurring several decades in the future as well as the role of core values in these processes. Thirty-six participants viewed a series of events, consisting of potential consequences of climate change, which could occur in the near future (around 2030), and thus would be experienced by the participants themselves, or in the far future (around 2080). We observed increased activation in anterior VMPFC (BA11), a region involved in encoding the personal significance of future events, when participants were envisioning far future events, demonstrating for the first time that the role of the VMPFC in future projection extends to the time scale of decades. Importantly, this activation increase was observed only in participants with pronounced self-transcendence values measured by self-report questionnaire, as shown by a statistically significant interaction of temporal distance and value structure. These findings suggest that future projection mechanisms are modulated by self-transcendence values to allow for a more extensive simulation of far future events. Consistent with this, these participants reported similar concern ratings for near and far future events, whereas participants with pronounced self-enhancement values were more concerned about near future events. Our findings provide a neural substrate for the tendency of individuals with pronounced self-transcendence values to consider the long-term consequences of their actions.

Beyond Hammers versus Hugs: Leveraging Educator Evaluation and Professional Learning Communities into Job-Embedded Professional Development

Science.gov (United States)

Woodland, Rebecca H.; Mazur, Rebecca

2015-01-01

Educational evaluation (Ed Eval) and professional learning communities (PLCs) are two of the nation's most predominant approaches to widespread instructional improvement. Yet key attributes of these reform initiatives are too often experienced by teachers as burdensome, or even detrimental, rather than helpful. The authors of this article contend…

Evaluating the future of HCI: challenges for the evaluation of emerging applications

NARCIS (Netherlands)

Poppe, Ronald Walter; Rienks, R.J.

2007-01-01

Current evaluation methods are inappropriate for emerging HCI applications. In this paper, we give three examples of these applications and show that traditional evaluation methods fail. We identify trends in HCI development and discuss the issues that arise with evaluation. We aim at achieving

Evaluating the Future of HCI : Challenges for the Evaluation of Emerging Applications

NARCIS (Netherlands)

Poppe, Ronald Walter; Rienks, R.J.; van Dijk, Elisabeth M.A.G.; Huang, T.S; Nijholt, Antinus; Pantic, Maja; Pentland, A.

2007-01-01

Current evaluation methods are inappropriate for emerging HCI applications. In this paper, we give three examples of these applications and show that traditional evaluation methods fail. We identify trends in HCI development and discuss the issues that arise with evaluation. We aim at achieving

Future ATM Concepts Evaluation Tool (FACET) Interface Control Document

Science.gov (United States)

Grabbe, Shon R.

2017-01-01

This Interface Control Document (ICD) documents the airspace adaptation and air traffic inputs of NASA's Future ATM Concepts and Evaluation Tool (FACET). Its intended audience is the project manager, project team, development team, and stakeholders interested in interfacing with the system. FACET equips Air Traffic Management (ATM) researchers and service providers with a way to explore, develop and evaluate advanced air transportation concepts before they are field-tested and eventually deployed. FACET is a flexible software tool that is capable of quickly generating and analyzing thousands of aircraft trajectories. It provides researchers with a simulation environment for preliminary testing of advanced ATM concepts. Using aircraft performance profiles, airspace models, weather data, and flight schedules, the tool models trajectories for the climb, cruise, and descent phases of flight for each type of aircraft. An advanced graphical interface displays traffic patterns in two and three dimensions, under various current and projected conditions for specific airspace regions or over the entire continental United States. The system is able to simulate a full day's dynamic national airspace system (NAS) operations, model system uncertainty, measure the impact of different decision-makers in the NAS, and provide analysis of the results in graphical form, including sector, airport, fix, and airway usage statistics. NASA researchers test and analyze the system-wide impact of new traffic flow management algorithms under anticipated air traffic growth projections on the nation's air traffic system. In addition to modeling the airspace system for NASA research, FACET has also successfully transitioned into a valuable tool for operational use. Federal Aviation Administration (FAA) traffic flow managers and commercial airline dispatchers have used FACET technology for real-time operations planning. FACET integrates live air traffic data from FAA radar systems and weather data

Blaming for a better future: future orientation and associated intolerance of personal uncertainty lead to harsher reactions toward innocent victims.

Science.gov (United States)

Bal, Michèlle; van den Bos, Kees

2012-07-01

People are often encouraged to focus on the future and strive for long-term goals. This noted, the authors argue that this future orientation is associated with intolerance of personal uncertainty, as people usually cannot be certain that their efforts will pay off. To be able to tolerate personal uncertainty, people adhere strongly to the belief in a just world, paradoxically resulting in harsher reactions toward innocent victims. In three experiments, the authors show that a future orientation indeed leads to more negative evaluations of an innocent victim (Study 1), enhances intolerance of personal uncertainty (Study 2), and that experiencing personal uncertainty leads to more negative evaluations of a victim (Study 3). So, while a future orientation enables people to strive for long-term goals, it also leads them to be harsher toward innocent victims. One underlying mechanism causing these reactions is intolerance of personal uncertainty, associated with a future orientation.

The detrimental impact of maladaptive personality on public mental health: a challenge for psychiatric practice

Directory of Open Access Journals (Sweden)

Michael Pascal Hengartner

2015-06-01

Full Text Available Experts in personality psychology and personality disorders have long emphasised the pervasive and persistent detrimental impact of maladaptive personality traits on mental health and functioning. However, in routine psychiatric practice maladaptive personality is readily ignored and personality traits are seldom incorporated into clinical guidelines. The aim of this narrative review is to outline how pervasively personality influences public mental health and how personality thereby challenges common psychiatric practice. A comprehensive search and synthesis of the scientific literature demonstrates that maladaptive personality traits and personality disorders, in particular high neuroticism and negative affectivity, first, are risk factors for divorce, unemployment and disability pensioning; second, relate to the prevalence, incidence and co-occurrence of common mental disorders; third, impair functioning, symptom remission and recovery in co-occurring common mental disorders; and fourth, predispose to treatment resistance, non-response and poor treatment outcome. In conclusion, maladaptive personality is not only involved in the development and course of mental disorders, but also predisposes to chronicity and re-occurrence of psychopathology and reduces the efficacy of psychiatric treatments. The pernicious impact of maladaptive personality on mental health and functioning demands that careful assessment and thorough consideration of personality should be compulsory in psychiatric practice.

Evaluating Cloud and Precipitation Processes in Numerical Models using Current and Potential Future Satellite Missions

Science.gov (United States)

van den Heever, S. C.; Tao, W. K.; Skofronick Jackson, G.; Tanelli, S.; L'Ecuyer, T. S.; Petersen, W. A.; Kummerow, C. D.

2015-12-01

Cloud, aerosol and precipitation processes play a fundamental role in the water and energy cycle. It is critical to accurately represent these microphysical processes in numerical models if we are to better predict cloud and precipitation properties on weather through climate timescales. Much has been learned about cloud properties and precipitation characteristics from NASA satellite missions such as TRMM, CloudSat, and more recently GPM. Furthermore, data from these missions have been successfully utilized in evaluating the microphysical schemes in cloud-resolving models (CRMs) and global models. However, there are still many uncertainties associated with these microphysics schemes. These uncertainties can be attributed, at least in part, to the fact that microphysical processes cannot be directly observed or measured, but instead have to be inferred from those cloud properties that can be measured. Evaluation of microphysical parameterizations are becoming increasingly important as enhanced computational capabilities are facilitating the use of more sophisticated schemes in CRMs, and as future global models are being run on what has traditionally been regarded as cloud-resolving scales using CRM microphysical schemes. In this talk we will demonstrate how TRMM, CloudSat and GPM data have been used to evaluate different aspects of current CRM microphysical schemes, providing examples of where these approaches have been successful. We will also highlight CRM microphysical processes that have not been well evaluated and suggest approaches for addressing such issues. Finally, we will introduce a potential NASA satellite mission, the Cloud and Precipitation Processes Mission (CAPPM), which would facilitate the development and evaluation of different microphysical-dynamical feedbacks in numerical models.

Future Scenarios for Plant Virus Pathogens as Climate Change Progresses.

Science.gov (United States)

Jones, R A C

2016-01-01

Knowledge of how climate change is likely to influence future virus disease epidemics in cultivated plants and natural vegetation is of great importance to both global food security and natural ecosystems. However, obtaining such knowledge is hampered by the complex effects of climate alterations on the behavior of diverse types of vectors and the ease by which previously unknown viruses can emerge. A review written in 2011 provided a comprehensive analysis of available data on the effects of climate change on virus disease epidemics worldwide. This review summarizes its findings and those of two earlier climate change reviews and focuses on describing research published on the subject since 2011. It describes the likely effects of the full range of direct and indirect climate change parameters on hosts, viruses and vectors, virus control prospects, and the many information gaps and deficiencies. Recently, there has been encouraging progress in understanding the likely effects of some climate change parameters, especially over the effects of elevated CO2, temperature, and rainfall-related parameters, upon a small number of important plant viruses and several key insect vectors, especially aphids. However, much more research needs to be done to prepare for an era of (i) increasingly severe virus epidemics and (ii) increasing difficulties in controlling them, so as to mitigate their detrimental effects on future global food security and plant biodiversity. © 2016 Elsevier Inc. All rights reserved.

Estimation and Evaluation of Future Demand and Supply of Healthcare Services Based on a Patient Access Area Model

Directory of Open Access Journals (Sweden)

Shunsuke Doi

2017-11-01

Full Text Available Accessibility to healthcare service providers, the quantity, and the quality of them are important for national health. In this study, we focused on geographic accessibility to estimate and evaluate future demand and supply of healthcare services. We constructed a simulation model called the patient access area model (PAAM, which simulates patients’ access time to healthcare service institutions using a geographic information system (GIS. Using this model, to evaluate the balance of future healthcare services demand and supply in small areas, we estimated the number of inpatients every five years in each area and compared it with the number of hospital beds within a one-hour drive from each area. In an experiment with the Tokyo metropolitan area as a target area, when we assumed hospital bed availability to be 80%, it was predicted that over 78,000 inpatients would not receive inpatient care in 2030. However, this number would decrease if we lowered the rate of inpatient care by 10% and the average length of the hospital stay. Using this model, recommendations can be made regarding what action should be undertaken and by when to prevent a dramatic increase in healthcare demand. This method can help plan the geographical resource allocation in healthcare services for healthcare policy.

Too much of a good thing: blocking noradrenergic facilitation in medial prefrontal cortex prevents the detrimental effects of chronic stress on cognition.

Science.gov (United States)

Jett, Julianne D; Morilak, David A

2013-03-01

Cognitive impairments associated with dysfunction of the medial prefrontal cortex (mPFC) are prominent in stress-related psychiatric disorders. We have shown that enhancing noradrenergic tone acutely in the rat mPFC facilitated extra-dimensional (ED) set-shifting on the attentional set-shifting test (AST), whereas chronic unpredictable stress (CUS) impaired ED. In this study, we tested the hypothesis that the acute facilitatory effect of norepinephrine (NE) in mPFC becomes detrimental when activated repeatedly during CUS. Using microdialysis, we showed that the release of NE evoked in mPFC by acute stress was unchanged at the end of CUS treatment. Thus, to then determine if repeated elicitation of this NE activity in mPFC during CUS may have contributed to the ED deficit, we infused a cocktail of α(1)-, β(1)-, and β(2)-adrenergic receptor antagonists into the mPFC prior to each CUS session, then tested animals drug free on the AST. Antagonist treatment prevented the CUS-induced ED deficit, suggesting that NE signaling during CUS compromised mPFC function. We confirmed that this was not attributable to sensitization of adrenergic receptor function following chronic antagonist treatment, by administering an additional microinjection into the mPFC immediately prior to ED testing. Acute antagonist treatment did not reverse the beneficial effects of chronic drug treatment during CUS, nor have any effect on baseline ED performance in chronic vehicle controls. Thus, we conclude that blockade of noradrenergic receptors in mPFC protected against the detrimental cognitive effects of CUS, and that repeated elicitation of noradrenergic facilitatory activity is one mechanism by which chronic stress may promote mPFC cognitive dysfunction.

Estimates of Health Detriments and Tissue Weighting Factors for Hong Kong Populations from Low Dose, Low Dose Rate and Low LET Ionising Radiation Exposure

International Nuclear Information System (INIS)

Lee, S.K.

1998-01-01

The total health detriments and the tissue weighting factors for the Hong Kong populations from low dose, low dose rate and low LET ionising radiation exposure are obtained according to the methodology recommended in ICRP Publication 60. The probabilities of fatal cancers for the general (ages 0-90) and working (ages 20-64) populations due to lifetime exposure at low dose and low dose rate are 4.9 x 10 -2 Sv -1 and 3.6 x 10 -2 Sv -1 respectively, comparing with the ICRP 60 estimates of 5.0 x 10 -2 Sv -1 and 4.0 x 10 -2 Sv -1 . The corresponding total health detriments for the general and working populations are 6.9 x 10 -2 Sv -1 and 4.9 x 10 -2 Sv -1 respectively comparing with the ICRP 60 estimates of 7.3 x 10 -2 Sv -1 and 5.6 x 10 -2 Sv -1 . Tissue weighting factors for the general population are 0.01 (bone surface and skin), 0.02 (liver, oesophagus and thyroid), 0.04 (bladder and breast), 0.08 (remainder), 0.10 (stomach), 0.11 (bone marrow), 0.15 (colon), 0.19 (lung) and 0.21 (gonads) and for the working population are 0.01 (bone surface and skin), 0.03 (liver, oesophagus and thyroid), 0.04 (breast), 0.06 (remainder), 0.07 (bladder), 0.08 (colon), 0.14 (bone marrow and stomach), 0.16 (lung) and 0.20 (gonads). (author)

Future Expectations, Attitude Toward Violence, and Bullying Perpetration During Early Adolescence: A Mediation Evaluation.

Science.gov (United States)

Stoddard, Sarah A; Varela, Jorge J; Zimmerman, Marc A

2015-01-01

Hopeful future expectations have been linked to positive developmental outcomes in adolescence; however, the association between future expectations and bullying perpetration has received less attention. We examined the relationship between future expectations and physical and relational bullying perpetration and tested a mediation model that linked future expectations with bullying through attitude toward violence. Structural equation modeling was used to examine the relationship between future expectations and bullying perpetration (relational and physical) and to test whether these relationships were mediated by attitude toward violence in a sample of U.S. seventh-grade students (Mage = 12.86 years, N = 196, 60% female, 46% African American). Attitude toward violence fully mediated the relationship between future expectations and physical bullying (indirect effects = -0.08, 95% CI [-0.15, -0.01], R = .17). The relationship between future expectations and relational bullying was partially mediated by attitudes toward violence (indirect effects = -0.07, 95% CI [-0.14, -0.002], R = .20). Our findings suggest that future expectations can play a role in reducing attitude toward violence and physical and relational bullying perpetration among youth. Interventions that help support the development of future goals and aspirations could play a vital role in bullying prevention efforts.

tDCS Stimulation of the dlPFC Selectively Moderates the Detrimental Impact of Emotion on Analytical Reasoning.

Science.gov (United States)

Trémolière, Bastien; Maheux-Caron, Véronique; Lepage, Jean-François; Blanchette, Isabelle

2018-01-01

There is evidence of a detrimental effect of emotion on reasoning. Recent studies suggest that this relationship is mediated by working memory, a function closely associated with the dorsolateral prefrontal cortex (dlPFC). Relying on transcranial direct current stimulation (tDCS), the present research explores the possibility that anodal stimulation of the dlPFC has the potential to prevent the effect of emotion on analytical reasoning. Thirty-four participants took part in a lab experiment and were tested twice: one session using offline anodal stimulation (with a 2 mA current stimulation applied to the left dlPFC for 20 min), one session using a control (sham) stimulation. In each session, participants solved syllogistic reasoning problems featuring neutral and emotionally negative contents. Results showed that anodal stimulation diminished the deleterious effect of emotion on syllogistic reasoning, but only for a subclass of problems: problems where the conclusion was logically valid. We discuss our results in the light of the reasoning literature as well as the apparent variability of tDCS effects.

Evaluating stakeholder participation in water management: intermediary outcomes as potential indicators for future resource management outcomes

Science.gov (United States)

Carr, Gemma; Bloeschl, Guenter; Loucks, Daniel Pete

2013-04-01

. Furthermore, failure to achieve intermediary outcomes correlates to failure to achieve resource management outcomes. Evaluating intermediary outcomes leads to both a broader assessment of a programme's achievements at the time of evaluation, and can indicate whether a programme will go on to achieve resource management objectives in the future.

Detrimental Cr-rich Phases Precipitation on SAF 2205 Duplex Stainless Steels Welds After Heat Treatment

Directory of Open Access Journals (Sweden)

Argelia Fabiola Miranda Pérez

Full Text Available Abstract The austeno-ferritic Stainless Steels are commonly employed in various applications requiring structural performances with enhanced corrosion resistance. Their characteristics can be worsened if the material is exposed to thermal cycles, since the high-temperature decomposition of ferrite causes the formation of detrimental secondary phases. The Submerged Arc Welding (SAW process is currently adopted for joining DSS owing to its relatively simple execution, cost savings, and using molten slag and granular flux from protecting the seam of atmospheric gases. However, since it produces high contents of δ-ferrite in the heat affected zone and low content of γ-austenite in the weld, high-Ni filler materials must be employed, to avoid excessive ferritization of the joint. The present work is aimed to study the effect of 3 and 6 hours isothermal heat treatments at 850°C and 900°C in a SAF 2205 DSS welded joint in terms of phases precipitation. The results showed the presence of σ-phase at any time-temperature combination, precipitating at the δ/γ interphases and often accompanied by the presence of χ-phase. However, certain differences in secondary phases amounts were revealed among the different zones constituting the joint, ascribable both to peculiar elements partitioning and to the different morphology pertaining to each microstructure.

Federal health web sites: current & future roles.

Science.gov (United States)

Cronin, Carol

2002-09-01

An examination of the current and possible future roles of federal health Web sites, this paper provides an overview of site categories, functions, target audiences, marketing approaches, knowledge management, and evaluation strategies. It concludes with a look at future opportunities and challenges for the federal government in providing health information online.

Evaluation of a High-Engagement Teaching Program for STEM Graduate Students: Outcomes of the Future Academic Scholars in Teaching (FAST) Fellowship Program

Science.gov (United States)

Prevost, Luanna B.; Vergara, Claudia E.; Urban-Lurain, Mark; Campa, Henry, III.

2018-01-01

Higher education institutions prepare future faculty members for multiple roles, including teaching. However, teaching professional development programs for graduate students vary widely. We present evaluation data from a high engagement program for STEM doctoral students. We analyzed the impact on three cohorts of participants over three academic…

The detrimental effects of iron on the joint: a comparison between haemochromatosis and haemophilia.

Science.gov (United States)

van Vulpen, Lize F D; Roosendaal, Goris; van Asbeck, B Sweder; Mastbergen, Simon C; Lafeber, Floris P J G; Schutgens, Roger E G

2015-08-01

Joint damage due to (recurrent) joint bleeding in haemophilia causes major morbidity. Although the exact pathogenesis has not been fully elucidated, a central role for iron is hypothesised. Likewise, in hereditary haemochromatosis joint destruction is caused by iron overload. A comparison between these types of arthropathy could provide more insight in the influence of iron in inducing joint damage. A literature review was performed to compare both disorders with respect to their clinical and histological characteristics, and preclinical studies on the influence of iron on different joint components were reviewed. Similarities in the features of arthropathy in haemochromatosis and haemophilia are cartilage degeneration, subchondral bone changes with osteophyte and cyst formation, and osteoporosis. In both disorders synovial inflammation and proliferation are seen, although this is much more explicit in haemophilia. Other substantial differences are the age at onset, the occurrence of chondrocalcinosis radiographically and calcium pyrophosphate dihydrate deposition disease in haemochromatosis, and a rapid progression with joint deformity and neovascularisation in haemophilia. Preclinical studies demonstrate detrimental effects of iron to all components of the joint, resulting in synovial inflammation and hyperplasia, chondrocyte death, and impaired osteoblast function. These effects, particularly the synovial changes, are aggravated in the presence of a pro-inflammatory signal, which is prominent in haemophilic arthropathy and minimal in haemochromatosis. Additional research is needed to further specify the role of iron as a specific target in treating these types of arthropathy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Evaluation of existing and proposed computer architectures for future ground-based systems

Science.gov (United States)

Schulbach, C.

1985-01-01

Parallel processing architectures and techniques used in current supercomputers are described and projections are made of future advances. Presently, the von Neumann sequential processing pattern has been accelerated by having separate I/O processors, interleaved memories, wide memories, independent functional units and pipelining. Recent supercomputers have featured single-input, multiple data stream architectures, which have different processors for performing various operations (vector or pipeline processors). Multiple input, multiple data stream machines have also been developed. Data flow techniques, wherein program instructions are activated only when data are available, are expected to play a large role in future supercomputers, along with increased parallel processor arrays. The enhanced operational speeds are essential for adequately treating data from future spacecraft remote sensing instruments such as the Thematic Mapper.

Adding sodium information to casual dining restaurant menus: Beneficial or detrimental for consumers?

Science.gov (United States)

Byrd, Karen; Almanza, Barbara; Ghiselli, Richard F; Behnke, Carl; Eicher-Miller, Heather A

2018-06-01

High sodium levels in restaurant food have prompted Philadelphia and New York City to require inclusion of sodium content in addition to calories on menus to "nudge" consumers toward lower sodium foods. However, taste perceptions may impact the effectiveness of this intervention. An online survey tested whether sodium and calorie menu nutrition information (MNI) influenced consumer choices from a casual dining restaurant menu, accounting for consumers' intuition about taste of food relative to sodium, calories, and healthiness. Consumer choices were assessed based on calorie and sodium content of the menu items they selected. Participants were randomized to a menu with (1) calorie MNI only, (2) calorie plus numeric sodium MNI, (3) calorie MNI plus a sodium warning symbol for foods with 2300 mg of sodium or more, or (4) no MNI. Calorie plus numeric sodium MNI was associated with selection of meals lower in sodium compared to meals from the calorie MNI only menu or no MNI menu, but only for consumers with a taste intuition that (relatively) lower sodium, lower calorie, healthy foods were tasty. Consumers with the opposite taste intuition *(foods with these characteristics are not tasty) ordered meals higher in sodium. Inclusion of the sodium warning symbol did not result in a significantly different meal sodium content compared to the other menu conditions, regardless of taste intuition. However, differing levels of taste intuition alone, without consideration of MNI, was associated with ordering meals of significantly different calorie content. Overall, findings suggest adding calorie plus numeric sodium MNI may lead to beneficial outcomes (i.e., selecting meals lower in sodium) for some consumers and detrimental outcomes (i.e., selecting meals higher in sodium) for others, depending on their taste intuition. Copyright © 2018 Elsevier Ltd. All rights reserved.

Adults with dyslexia demonstrate large effects of crowding and detrimental effects of distractors in a visual tilt discrimination task.

Directory of Open Access Journals (Sweden)

Rizan Cassim

Full Text Available Previous research has shown that adults with dyslexia (AwD are disproportionately impacted by close spacing of stimuli and increased numbers of distractors in a visual search task compared to controls [1]. Using an orientation discrimination task, the present study extended these findings to show that even in conditions where target search was not required: (i AwD had detrimental effects of both crowding and increased numbers of distractors; (ii AwD had more pronounced difficulty with distractor exclusion in the left visual field and (iii measures of crowding and distractor exclusion correlated significantly with literacy measures. Furthermore, such difficulties were not accounted for by the presence of covarying symptoms of ADHD in the participant groups. These findings provide further evidence to suggest that the ability to exclude distracting stimuli likely contributes to the reported visual attention difficulties in AwD and to the aetiology of literacy difficulties. The pattern of results is consistent with weaker and asymmetric attention in AwD.

Ego depletion in color priming research: self-control strength moderates the detrimental effect of red on cognitive test performance.

Science.gov (United States)

Bertrams, Alex; Baumeister, Roy F; Englert, Chris; Furley, Philip

2015-03-01

Colors have been found to affect psychological functioning. Empirical evidence suggests that, in test situations, brief perceptions of the color red or even the word "red" printed in black ink prime implicit anxious responses and consequently impair cognitive performance. However, we propose that this red effect depends on people's momentary capacity to exert control over their prepotent responses (i.e., self-control). In three experiments (Ns = 66, 78, and 130), first participants' self-control strength was manipulated. Participants were then primed with the color or word red versus gray prior to completing an arithmetic test or an intelligence test. As expected, self-control strength moderated the red effect. While red had a detrimental effect on performance of participants with depleted self-control strength (ego depletion), it did not affect performance of participants with intact self-control strength. We discuss implications of the present findings within the current debate on the robustness of priming results. © 2015 by the Society for Personality and Social Psychology, Inc.

Future Contract Selection by Term Structure Analysis

Directory of Open Access Journals (Sweden)

Vasco Grossmann

2017-07-01

Full Text Available In futures markets, a single asset is generally represented by several contracts with different maturities. The selection of specific contracts is an inevitable task that also creates new opportunities, especially in terms of speculative trading. Evaluating immediate and upcoming trading costs for all considered contracts might lead to a significantly improved performance. Among that, even possible market inefficiencies might be taken into consideration. This research introduces and evaluates a new algorithm for the contract selection. The results are benchmarked and compared with established methods using a Monte Carlo simulation on different commodity and index futures.

The role of adenosine receptor agonist and antagonist on Hippocampal MDMA detrimental effects; a structural and behavioral study.

Science.gov (United States)

Kermanian, Fatemeh; Mehdizadeh, Mehdi; Soleimani, Mansureh; Ebrahimzadeh Bideskan, Ali Reza; Asadi-Shekaari, Majid; Kheradmand, Hamed; Haghir, Hossein

2012-12-01

There is abundant evidence showing that repeated use of MDMA (3, 4-Methylenedioxymethamphetamine, ecstasy) has been associated with depression, anxiety and deficits in learning and memory, suggesting detrimental effects on hippocampus. Adenosine is an endogenous purine nucleoside that has a neuromodulatory role in the central nervous system. In the present study, we investigated the role of A2a adenosine receptors agonist (CGS) and antagonist (SCH) on the body temperature, learning deficits, and hippocampal cell death induced by MDMA administration. In this study, 63 adult, male, Sprague - Dawley rats were subjected to MDMA (10 and 20 mg/kg) followed by intraperitoneal CGS (0.03 mg/kg) or SCH (0.03 mg/kg) injection. The animals were tested for spatial learning in the Morris water maze (MWM) task performance, accompanied by a recording of body temperature, electron microscopy and stereological study. Our results showed that MDMA treatment increased body temperature significantly, and impaired the ability of rats to locate the hidden platform(P learning deficits observed in MDMA users. However, the exact mechanism of these interactions requires further studies.

EVALUATING THE IMPACT OF POLICY OPTIONS ON AGRICULTURAL LANDSCAPES: AN ALTERNATIVE-FUTURES APPROACH

Science.gov (United States)

Alternative-futures analysis was used to analyze different scenarios of future growth patterns and attendant resource allocations on the agricultural system of Oregon's Willamette River Basin. A stakeholder group formulated three policy alternatives: a continuation of current tr...

Comparative evaluation of the influence of television advertisements on children and caries prevalence

OpenAIRE

Ghimire, Neeta; Rao, Arathi

2013-01-01

Introduction: Children watch television during most of their free time. They are exposed to advertisers’ messages and are vulnerable to sophisticated advertisements of foods often detrimental to oral and general health.Objectives: To evaluate the influence of television advertisements on children, the relationship with oral health and to analyze the content of those advertisements.Methodology: A questionnaire-based study was performed among 600 schoolchildren of Mangalore, Karnataka, followed...

Tools and methods for evaluating and refining alternative futures for coastal ecosystem management—the Puget Sound Ecosystem Portfolio Model

Science.gov (United States)

Byrd, Kristin B.; Kreitler, Jason R.; Labiosa, William B.

2011-01-01

The U.S. Geological Survey Puget Sound Ecosystem Portfolio Model (PSEPM) is a decision-support tool that uses scenarios to evaluate where, when, and to what extent future population growth, urban growth, and shoreline development may threaten the Puget Sound nearshore environment. This tool was designed to be used iteratively in a workshop setting in which experts, stakeholders, and decisionmakers discuss consequences to the Puget Sound nearshore within an alternative-futures framework. The PSEPM presents three possible futures of the nearshore by analyzing three growth scenarios developed out to 2060: Status Quo—continuation of current trends; Managed Growth—adoption of an aggressive set of land-use management policies; and Unconstrained Growth—relaxation of land-use restrictions. The PSEPM focuses on nearshore environments associated with barrier and bluff-backed beaches—the most dominant shoreforms in Puget Sound—which represent 50 percent of Puget Sound shorelines by length. This report provides detailed methodologies for development of three submodels within the PSEPM—the Shellfish Pollution Model, the Beach Armoring Index, and the Recreation Visits Model. Results from the PSEPM identify where and when future changes to nearshore ecosystems and ecosystem services will likely occur within the three growth scenarios. Model outputs include maps that highlight shoreline sections where nearshore resources may be at greater risk from upland land-use changes. The background discussed in this report serves to document and supplement model results displayed on the PSEPM Web site located at http://geography.wr.usgs.gov/pugetSound/.

Nuclear power as a public issue: Protection of the public interest

International Nuclear Information System (INIS)

Doederlein, J.M.

1978-01-01

In evaluating the desired role of nuclear power, the overall perspective of the role of energy in society should be applied. Views on the role of electric energy and its production forms need to be integrated in an overall cost-risk-benefit analysis on overall economic growth, energy use and energy conservation. The formidable difficulties of total cost-risk-benefit analyses (predicting the values of future societies, devising accounting methods for weighting present and future costs and benefits, feedback between development of largescale technology and the development of societal values and of society, etc.) should make us settle for less comprehensive and perhaps semiquantitative analyses. The necessary technological and scientific basis for useful analysis is available. The societal risk-benefit criteria, the institutional apparatus, and the political ability and willingness to apply rational cost-risk-benefit analyses do not seem to be equally well developed. A specific difficulty for evaluations of electric power production systems is the incomplete analysis of the benefit, electricity. There is a detrimental lack of factual, detailed and understandable data on the benefit of electric power within a systematic structure of categories similar to that used for analyses of detrimental impacts of power production and use

An evaluation of alternate containment concepts for severe accident sequences: Chapter 3

International Nuclear Information System (INIS)

Ashton, D.H.; Blazo, S.R.

1983-01-01

Over the past several years, numerous design concepts have been developed to enhance the ability of containments to withstand severe reactor accidents. As part of the AIF sponsored IDCOR program, a study has been completed to survey and evaluate these alternate containment design concepts. The study defines the minimum as well as optimum functional and design criteria which any such system must meet. Six concepts which satisfy these criteria are then evaluated based upon factors such as: risk reduction potential, cost, constructability and the potential detrimental effects. Based upon the results of these evaluations, a ranking of the design concepts is developed. The purpose of this paper is to present the results of the IDCOR sponsored study

Evaluation of the productivity decrease risk due to a future increase in tropical cyclone intensity in Japan.

Science.gov (United States)

Esteban, Miguel; Longarte-Galnares, Gorka

2010-12-01

A number of scientists have recently conducted research that shows that tropical cyclone intensity is likely to increase in the future. This would result in an increase in the damage along with a decrease in economic productivity due to precautionary cessation of the economic activity of the affected areas during the passage of the cyclone. The economic effect of this stop in economic activity is a phenomenon that has not received much attention in the past, and the cumulative effect that it can have on the Japanese economy over the next 75 years has never been evaluated. The starting point for the evaluation of the economic risks is the change in the patterns of tropical cyclone intensity suggested by Knutson and Tuleya. The results obtained show how a significant decrease in the overall productivity of the country could be expected, which could lower GDP by between 6% and 13% by 2085. © 2010 Society for Risk Analysis.

The Nonmydriatic Fundus Camera in Diabetic Retinopathy Screening: A Cost-Effective Study with Evaluation for Future Large-Scale Application

Directory of Open Access Journals (Sweden)

Giuseppe Scarpa

2016-01-01

Full Text Available Aims. The study aimed to present the experience of a screening programme for early detection of diabetic retinopathy (DR using a nonmydriatic fundus camera, evaluating the feasibility in terms of validity, resources absorption, and future advantages of a potential application, in an Italian local health authority. Methods. Diabetic patients living in the town of Ponzano, Veneto Region (Northern Italy, were invited to be enrolled in the screening programme. The “no prevention strategy” with the inclusion of the estimation of blindness related costs was compared with screening costs in order to evaluate a future extensive and feasible implementation of the procedure, through a budget impact approach. Results. Out of 498 diabetic patients eligible, 80% was enrolled in the screening programme. 115 patients (34% were referred to an ophthalmologist and 9 cases required prompt treatment for either proliferative DR or macular edema. Based on the pilot data, it emerged that an extensive use of the investigated screening programme, within the Greater Treviso area, could prevent 6 cases of blindness every year, resulting in a saving of €271,543.32 (−13.71%. Conclusions. Fundus images obtained with a nonmydriatic fundus camera could be considered an effective, cost-sparing, and feasible screening tool for the early detection of DR, preventing blindness as a result of diabetes.

Futuring for Future Ready Librarians

Science.gov (United States)

Figueroa, Miguel A.

2018-01-01

Futurists and foresight professionals offer several guiding principles for thinking about the future. These principles can help people to think about the future and become more powerful players in shaping the preferred futures they want for themselves and their communities. The principles also fit in well as strategies to support the Future Ready…

Evaluation of Waste Arising from Future Nuclear Fuel Cycle

International Nuclear Information System (INIS)

Jubin, Robert Thomas; Taiwo, Temitope; Wigeland, Roald

2015-01-01

A comprehensive study was recently completed at the request of the US Department of Energy Office of Nuclear Energy (DOE-NE) to evaluate and screen nuclear fuel cycles. The final report was issued in October 2014. Uranium- and thorium-based fuel cycles were evaluated using both fast and thermal spectrum reactors. Once-through, limited-recycle, and continuous-recycle cases were considered. This study used nine evaluation criteria to identify promising fuel cycles. Nuclear waste management was one of the nine evaluation criteria. The waste generation criterion from this study is discussed herein.

On evaluation of assessments of accruals of future dismantling costs

Energy Technology Data Exchange (ETDEWEB)

Labor, Bea [B D Projects 2013, Gdansk (Poland); Lindskog, Staffan [Swedish Radiation Safety Authority, Solna (Sweden)

2013-07-01

A major prerequisite in order for civilian commercial nuclear energy production to qualify as sustainable energy production is that systems for the management of the nuclear waste legacy are in operation. These waste types are present in a range from very low short lived waste (VLLW) to long lived high level waste (HLW) (including the used nuclear fuel). The second prerequisite is that financial responsibilities or other constraints must not be passed on to coming generations. The first condition for qualification corresponds to the Polluters Pays Principle (PPP) which demands that the responsibility for the waste management rests solely with the polluter. The second qualification corresponds to the principle of fairness between generations and thus concerns the appropriate distribution of responsibilities between the generations. It is important to note that these two conditions must be met simultaneously, and that compliance with both is a necessary prerequisite in order for commercial use of nuclear power to qualify as a semi-sustainable energy source. Financial and technical planning for dismantling and decommissioning of nuclear installations cannot be regarded as successful unless it rests upon a distinctive way to describe and explain the well-founded values of different groups of stakeholders. This cumbersome task can be underpinned by transparent and easy to grasp models for calculation and estimation of future environmental liabilities. It essential that a systematic classification is done of all types of costs and that an effort is done to evaluate the precision level in the cost estimates. In this paper, a systematic and transparent way to develop a parametric approach that rest upon basic accounting standards is combined with data about younger stakeholder's values towards decommissioning and dismantling of nuclear installation. The former entity rests upon theoretical and practical methods from business administration, whilst the latter is based

On evaluation of assessments of accruals of future dismantling costs

International Nuclear Information System (INIS)

Labor, Bea; Lindskog, Staffan

2013-01-01

A major prerequisite in order for civilian commercial nuclear energy production to qualify as sustainable energy production is that systems for the management of the nuclear waste legacy are in operation. These waste types are present in a range from very low short lived waste (VLLW) to long lived high level waste (HLW) (including the used nuclear fuel). The second prerequisite is that financial responsibilities or other constraints must not be passed on to coming generations. The first condition for qualification corresponds to the Polluters Pays Principle (PPP) which demands that the responsibility for the waste management rests solely with the polluter. The second qualification corresponds to the principle of fairness between generations and thus concerns the appropriate distribution of responsibilities between the generations. It is important to note that these two conditions must be met simultaneously, and that compliance with both is a necessary prerequisite in order for commercial use of nuclear power to qualify as a semi-sustainable energy source. Financial and technical planning for dismantling and decommissioning of nuclear installations cannot be regarded as successful unless it rests upon a distinctive way to describe and explain the well-founded values of different groups of stakeholders. This cumbersome task can be underpinned by transparent and easy to grasp models for calculation and estimation of future environmental liabilities. It essential that a systematic classification is done of all types of costs and that an effort is done to evaluate the precision level in the cost estimates. In this paper, a systematic and transparent way to develop a parametric approach that rest upon basic accounting standards is combined with data about younger stakeholder's values towards decommissioning and dismantling of nuclear installation. The former entity rests upon theoretical and practical methods from business administration, whilst the latter is based

Future Shop: A Model Career Placement & Transition Laboratory.

Science.gov (United States)

Floyd, Deborah L.; And Others

During 1988-89, the Collin County Community College District (CCCCD) conducted a project to develop, implement, and evaluate a model career laboratory called a "Future Shop." The laboratory was designed to let users explore diverse career options, job placement opportunities, and transfer resources. The Future Shop lab had three major components:…

Reflections and Future Prospects for Evaluation in Human Resource Development

Science.gov (United States)

Han, Heeyoung; Boulay, David

2013-01-01

Human resource development (HRD) evaluation has often been criticized for its limited function in organizational decision making. This article reviews evaluation studies to uncover the current status of HRD evaluation literature. The authors further discuss general evaluation theories in terms of value, use, and evaluator role to extend the…

Benefits and detriments of unilateral cochlear implant use on bilateral auditory development in children who are deaf

Directory of Open Access Journals (Sweden)

Karen A. Gordon

2013-10-01

Full Text Available We have explored both the benefits and detriments of providing electrical input through a cochlear implant in one ear to the auditory system of young children. A cochlear implant delivers electrical pulses to stimulate the auditory nerve, providing children who are deaf with access to sound. The goals of implantation are to restrict reorganization of the deprived immature auditory brain and promote development of hearing and spoken language. It is clear that limiting the duration of deprivation is a key factor. Additional considerations are the onset, etiology, and use of residual hearing as each of these can have unique effects on auditory development in the pre-implant period. New findings show that many children receiving unilateral cochlear implants are developing mature-like brainstem and thalamo-cortical responses to sound with long term use despite these sources of variability; however, there remain considerable abnormalities in cortical function. The most apparent, determined by implanting the other ear and measuring responses to acute stimulation, is a loss of normal cortical response from the deprived ear. Recent data reveal that this can be avoided in children by early implantation of both ears simultaneously or with limited delay. We conclude that auditory development requires input early in development and from both ears.

Air pollution and detrimental effects on children's brain. The need for a multidisciplinary approach to the issue complexity and challenges.

Science.gov (United States)

Calderón-Garcidueñas, Lilian; Torres-Jardón, Ricardo; Kulesza, Randy J; Park, Su-Bin; D'Angiulli, Amedeo

2014-01-01

Millions of children in polluted cities are showing brain detrimental effects. Urban children exhibit brain structural and volumetric abnormalities, systemic inflammation, olfactory, auditory, vestibular and cognitive deficits v low-pollution controls. Neuroinflammation and blood-brain-barrier (BBB) breakdown target the olfactory bulb, prefrontal cortex and brainstem, but are diffusely present throughout the brain. Urban adolescent Apolipoprotein E4 carriers significantly accelerate Alzheimer pathology. Neurocognitive effects of air pollution are substantial, apparent across all populations, and potentially clinically relevant as early evidence of evolving neurodegenerative changes. The diffuse nature of the neuroinflammation and neurodegeneration forces to employ a weight of evidence approach incorporating current clinical, cognitive, neurophysiological, radiological and epidemiological research. Pediatric air pollution research requires extensive multidisciplinary collaborations to accomplish a critical goal: to protect exposed children through multidimensional interventions having both broad impact and reach. Protecting children and teens from neural effects of air pollution should be of pressing importance for public health.

Active power reserves evaluation in large scale PVPPs

DEFF Research Database (Denmark)

Crăciun, Bogdan-Ionut; Kerekes, Tamas; Sera, Dezso

2013-01-01

The present trend on investing in renewable ways of producing electricity in the detriment of conventional fossil fuel-based plants will lead to a certain point where these plants have to provide ancillary services and contribute to overall grid stability. Photovoltaic (PV) power has the fastest...... growth among all renewable energies and managed to reach high penetration levels creating instabilities which at the moment are corrected by the conventional generation. This paradigm will change in the future scenarios where most of the power is supplied by large scale renewable plants and parts...... of the ancillary services have to be shared by the renewable plants. The main focus of the proposed paper is to technically and economically analyze the possibility of having active power reserves in large scale PV power plants (PVPPs) without any auxiliary storage equipment. The provided reserves should...

Development of a MPPC-based prototype gantry for future MRI-PET scanners

Science.gov (United States)

Kurei, Y.; Kataoka, J.; Kato, T.; Fujita, T.; Ohshima, T.; Taya, T.; Yamamoto, S.

2014-12-01

We have developed a high spatial resolution, compact Positron Emission Tomography (PET) module designed for small animals and intended for use in magnetic resonance imaging (MRI) systems. This module consists of large-area, 4 × 4 ch MPPC arrays (S11830-3344MF; Hamamatsu Photonics K.K.) optically coupled with Ce-doped (Lu,Y)2(SiO4)O (Ce:LYSO) scintillators fabricated into 16 × 16 matrices of 0.5 × 0.5 mm2 pixels. We set the temperature sensor (LM73CIMK-0; National Semiconductor Corp.) at the rear of the MPPC acceptance surface, and apply optimum voltage to maintain the gain. The eight MPPC-based PET modules and coincidence circuits were assembled into a gantry arranged in a ring 90 mm in diameter to form the MPPC-based PET system. We have developed two types PET gantry: one made of non-magnetic metal and the other made of acrylonitrile butadiene styrene (ABS) resins. The PET gantry was positioned around the RF coil of the 4.7 T MRI system. We took an image of a point }22Na source under fast spin echo (FSE) and gradient echo (GE), in order to measure the interference between the MPPC-based PET and MRI. The spatial resolution of PET imaging in a transaxial plane of about 1 mm (FWHM) was achieved in all cases. Operating with PET made of ABS has no effect on MR images, while operating with PET made of non-magnetic metal has a significant detrimental effect on MR images. This paper describes our quantitative evaluations of PET images and MR images, and presents a more advanced version of the gantry for future MRI/DOI-PET systems.

Water and Land Limitations to Future Agricultural Production in the Middle East

Science.gov (United States)

Koch, J. A. M.; Wimmer, F.; Schaldach, R.

2015-12-01

Countries in the Middle East use a large fraction of their scarce water resources to produce cash crops, such as fruit and vegetables, for international markets. At the same time, these countries import large amounts of staple crops, such as cereals, required to meet the nutritional demand of their populations. This makes food security in the Middle East heavily dependent on world market prices for staple crops. Under these preconditions, increasing food demand due to population growth, urban expansion on fertile farmlands, and detrimental effects of a changing climate on the production of agricultural commodities present major challenges to countries in the Middle East that try to improve food security by increasing their self-sufficiency rate of staple crops.We applied the spatio-temporal land-use change model LandSHIFT.JR to simulate how an expansion of urban areas may affect the production of agricultural commodities in Jordan. We furthermore evaluated how climate change and changes in socio-economic conditions may influence crop production. The focus of our analysis was on potential future irrigated and rainfed production (crop yield and area demand) of fruit, vegetables, and cereals. Our simulation results show that the expansion of urban areas and the resulting displacement of agricultural areas does result in a slight decrease in crop yields. This leads to almost no additional irrigation water requirements due to the relocation of agricultural areas, i.e. there is the same amount of "crop per drop". However, taking into account projected changes in socio-economic conditions and climate conditions, a large volume of water would be required for cereal production in order to safeguard current self-sufficiency rates for staple crops. Irrigation water requirements are expected to double until 2025 and to triple until 2050. Irrigated crop yields are projected to decrease by about 25%, whereas there is no decrease in rainfed crop yields to be expected.

Using 3D Multi-Body Simulation to Evaluate Future Truck Technologies

National Research Council Canada - National Science Library

Gunter, Dave; Bylsma, Wes; Letherwood, Mike; Dennis, Stacey; Argeropoulos, Kris; Teschendorf, Dan; Gorsich, Dave

2004-01-01

... steering, and in-hub electric drive motors. Fully three-dimensional Future Truck models were created using a commercially available modeling and simulation methodology and limited validation studies were performed by comparing model...

Productivity costs in economic evaluations: past, present, future.

Science.gov (United States)

Krol, Marieke; Brouwer, Werner; Rutten, Frans

2013-07-01

Productivity costs occur when the productivity of individuals is affected by illness, treatment, disability or premature death. The objective of this paper was to review past and current developments related to the inclusion, identification, measurement and valuation of productivity costs in economic evaluations. The main debates in the theory and practice of economic evaluations of health technologies described in this review have centred on the questions of whether and how to include productivity costs, especially productivity costs related to paid work. The past few decades have seen important progress in this area. There are important sources of productivity costs other than absenteeism (e.g. presenteeism and multiplier effects in co-workers), but their exact influence on costs remains unclear. Different measurement instruments have been developed over the years, but which instrument provides the most accurate estimates has not been established. Several valuation approaches have been proposed. While empirical research suggests that productivity costs are best included in the cost side of the cost-effectiveness ratio, the jury is still out regarding whether the human capital approach or the friction cost approach is the most appropriate valuation method to do so. Despite the progress and the substantial amount of scientific research, a consensus has not been reached on either the inclusion of productivity costs in economic evaluations or the methods used to produce productivity cost estimates. Such a lack of consensus has likely contributed to ignoring productivity costs in actual economic evaluations and is reflected in variations in national health economic guidelines. Further research is needed to lessen the controversy regarding the estimation of health-related productivity costs. More standardization would increase the comparability and credibility of economic evaluations taking a societal perspective.

Universe, human immortality and future human evaluation

CERN Document Server

Bolonkin, Alexander

2011-01-01

This book debates the universe, the development of new technologies in the 21st century and the future of the human race. Dr Bolonkin shows that a human soul is only the information in a person's head. He offers a new unique method for re-writing the main brain information in chips without any damage to the human brain. This is the scientific prediction of the non-biological (electronic) civilization and immortality of the human being. Such a prognosis is predicated upon a new law, discovered by the author, for the development of complex systems. According to this law, every self-copying system tends to be more complex than the previous system, provided that all external conditions remain the same. The consequences are disastrous: humanity will be replaced by a new civilization created by intellectual robots (which Dr Bolonkin refers to as "E-humans" and "E-beings"). These creatures, whose intellectual and mechanical abilities will far exceed those of man, will require neither food nor oxygen to sustain their...

Navy Telemedicine: Current Research and Future Directions

National Research Council Canada - National Science Library

Reed, Cheryl

2002-01-01

.... This report reviews military and civilian models for evaluating telemedicine systems in order to determine future directions for Navy telemedicine research within the current funding environment...

Disaggregation of collective dose-a worked example based on future discharges from the Sellafield nuclear fuel reprocessing site, UK

International Nuclear Information System (INIS)

Jones, S R; Lambers, B; Stevens, A

2004-01-01

Collective dose has long been advocated as an important measure of the detriment associated with practices that involve the use of radioactivity. Application of collective dose in the context of worker protection is relatively straightforward, whereas its application in the context of discharges to the environment can yield radically different conclusions depending upon the population groups and integration times that are considered. The computer program PC-CREAM98 has been used to provide an indicative disaggregation into individual dose bands of the collective dose due to potential future radioactive discharges from the nuclear fuel reprocessing site at Sellafield in the UK. Two alternative discharge scenarios are considered, which represent a 'stop reprocessing early, minimum discharge' scenario and a 'reprocessing beyond current contracts' scenario. For aerial discharges, collective dose at individual effective dose rates exceeding 0.015 μSv y -1 is only incurred within the UK, and at effective dose rates exceeding 1.5 μSv y -1 is only incurred within about 20 km of Sellafield. The geographical distribution of collective dose from liquid discharges is harder to assess, but it appears that collective dose incurred outside the UK is at levels of individual effective dose rate below 1.5 μSv y -1 , with the majority being incurred at rates of 0.002 μSv y -1 or less. In multi-attribute utility analyses, the view taken on the radiological detriment to be attributed to the two discharge scenarios will depend critically on the weight or monetary value ascribed to collective doses incurred within the differing bands of individual dose rate

Quantifying Health Utilities in Patients Undergoing Stereotactic Body Radiation Treatment for Liver Metastases for Use in Future Economic Evaluations.

Science.gov (United States)

Warren, B; Munoz-Schuffenegger, P; Chan, K K W; Chu, W; Helou, J; Erler, D; Chung, H

2017-09-01

Stereotactic body radiation therapy (SBRT) is increasingly used as an option for those with liver metastases. In order to facilitate future economic impact of health technologies, health utility scores may be used. The EuroQOL-5D-3L (EQ-5D) preference-based healthy utility instrument was used to evaluate the impact of treatment with SBRT on health utility scores. Between August 2013 and October 2014, 31 patients treated with 3-5 fractions of SBRT for liver metastases were enrolled in this study. The EQ-5D instrument was administered at baseline, during and up to 6 months post-SBRT. Mean EQ-5D score at baseline was 0.857, which remained stable across the entire study time period. Transient increases in difficulties with mobility (9.7% reported at baseline to 16.1% on the last day of treatment) and usual activities (3.2% reported at baseline to 34.5% on day two) were found during the course of treatment; these returned to baseline levels subsequently. The mean visual analogue score at baseline was 65.8 and remained unchanged throughout treatment and follow-up. The stability of health utility scores and problems reported by patients undergoing treatment indicate that SBRT for liver metastases does not impart a significant adverse effect on quality of life. These results may be used for future economic evaluation of SBRT. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Ethics Beyond Finitude: Responsibility towards Future Generations and Nuclear Waste Management

International Nuclear Information System (INIS)

Loefquist, Lars

2008-01-01

This dissertation has three aims: 1. To evaluate several ethical theories about responsibility towards future generations. 2. To construct a theory about responsibility towards future generations. 3. To carry out an ethical evaluation of different nuclear waste management methods. Five theories are evaluated with the help of evaluative criteria, primarily: A theory must provide future generations with some independent moral status. A theory should acknowledge moral pluralism. A theory should provide some normative claims about real-world problems. Derek Parfit's theory provides future generations with full moral status. But it is incompatible with moral pluralism, and does not provide reasonable normative claims about real-world problems. Brian Barry's theory provides such claims and a useful idea about risk management, but it does not provide an argument why future generations ought to exist. Avner de-Shalit's theory explains why they ought to exist; however, his theory can not easily explain why we ought to care for other people than those in our own community. Emmanuel Agius' theory gives an ontological explanation for mankind's unity, but reduces conflicts of interests to a common good. Finally, Hans Jonas' theory shifts the focus from the situation of future generations to the preconditions of human life generally. However, his theory presupposes a specific ontology, which might be unable to motivate people to act. The concluding chapters describe a narrative theory of responsibility. It claims that we should comprehend ourselves as parts of the common story of mankind and that we ought to provide future generations with equal opportunities. This implies that we should avoid transferring risks and focus on reducing the long-term risks associated with the nuclear waste

Past and Future Cost of Wind Energy: Preprint

Energy Technology Data Exchange (ETDEWEB)

Lantz, E.; Hand, M.; Wiser, R.

2012-08-01

The future of wind power will depend on the ability of the industry to continue to achieve cost reductions. To better understand the potential for cost reductions, this report provides a review of historical costs, evaluates near-term market trends, and summarizes the range of projected costs. It also notes potential sources of future cost reductions.

Evaluation of Role 2 (R2) Medical Resources in the Afghanistan Combat Theater: Past, Present and Future

Science.gov (United States)

2017-10-01

those of the author(s) and should not be construed  as an official Department of the Army position, policy or  decision  unless so designated by other...sustainment and evaluation for medical staff (physicians, nurses , other licensed professionals, medics) deployed to the R2 environment. 15. SUBJECT TERMS...leaders will be unable to best allocate R2  resources in future operations. Furthermore, the  clinical  competencies required for each medical team member to

FutureCoast: "Listen to your futures"

Science.gov (United States)

Pfirman, S. L.; Eklund, K.; Thacher, S.; Orlove, B. S.; Diane Stovall-Soto, G.; Brunacini, J.; Hernandez, T.

2014-12-01

Two science-arts approaches are emerging as effective means to convey "futurethinking" to learners: systems gaming and experiential futures. FutureCoast exemplifies the latter: by engaging participants with voicemails supposedly leaking from the cloud of possible futures, the storymaking game frames the complexities of climate science in relatable contexts. Because participants make the voicemails themselves, FutureCoast opens up creative ways for people to think about possibly climate-changed futures and personal ways to talk about them. FutureCoast is a project of the PoLAR Partnership with a target audience of informal adult learners primarily reached via mobile devices and online platforms. Scientists increasingly use scenarios and storylines as ways to explore the implications of environmental change and societal choices. Stories help people make connections across experiences and disciplines and link large-scale events to personal consequences. By making the future seem real today, FutureCoast's framework helps people visualize and plan for future climate changes. The voicemails contributed to FutureCoast are spread through the game's intended timeframe (2020 through 2065). Based on initial content analysis of voicemail text, common themes include ecosystems and landscapes, weather, technology, societal issues, governance and policy. Other issues somewhat less frequently discussed include security, food, industry and business, health, energy, infrastructure, water, economy, and migration. Further voicemail analysis is examining: temporal dimensions (salient time frames, short vs. long term issues, intergenerational, etc.), content (adaptation vs. mitigation, challenges vs. opportunities, etc.), and emotion (hopeful, resigned, etc. and overall emotional context). FutureCoast also engaged audiences through facilitated in-person experiences, geocaching events, and social media (Tumblr, Twitter, Facebook, YouTube). Analysis of the project suggests story

Selecting reasonable future land use scenarios

Energy Technology Data Exchange (ETDEWEB)

Allred, W.E.; Smith, R.W. [Idaho National Engineering Lab., Idaho Falls, ID (United States)

1995-12-31

This paper examines a process to help select the most reasonable future land use scenarios for hazardous waste and/or low-level radioactive waste disposal sites. The process involves evaluating future land use scenarios by applying selected criteria currently used by commercial mortgage companies to determine the feasibility of obtaining a loan for purchasing such land. The basis for the process is that only land use activities for which a loan can be obtained will be considered. To examine the process, a low-level radioactive waste site, the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory, is used as an example. The authors suggest that the process is a very precise, comprehensive, and systematic (common sense) approach for determining reasonable future use of land. Implementing such a process will help enhance the planning, decisionmaking, safe management, and cleanup of present and future disposal facilities.

Selecting reasonable future land use scenarios

International Nuclear Information System (INIS)

Allred, W.E.; Smith, R.W.

1995-01-01

This paper examines a process to help select the most reasonable future land use scenario for hazardous waste and/or low-level radioactive waste disposal sites. The process involves evaluating future land use scenarios ab applying selected criteria currently used by commercial mortgage companies to determine the feasibility of obtaining a loan for purchasing such land. The basis for the process is that only land use activities for which a loan can be obtained well be considered. To examine the process, a low-level radioactive waste site, the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory, is used as an example. The authors suggest that the process is a very precise, comprehensive, and systematic approach for determining reasonable future use of land. Implementing such a process will help enhance the planning, decisionmaking, safe management, and cleanup of present and future disposal facilities

Selecting reasonable future land use scenarios

International Nuclear Information System (INIS)

Allred, W.E.; Smith, R.W.

1995-01-01

This paper examines a process to help select the most reasonable future land use scenarios for hazardous waste and/or low-level radioactive waste disposal sites. The process involves evaluating future land use scenarios by applying selected criteria currently used by commercial mortgage companies to determine the feasibility of obtaining a loan for purchasing such land. The basis for the process is that only land use activities for which a loan can be obtained will be considered. To examine the process, a low-level radioactive waste site, the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory, is used as an example. The authors suggest that the process is a very precise, comprehensive, and systematic (common sense) approach for determining reasonable future use of land. Implementing such a process will help enhance the planning, decisionmaking, safe management, and cleanup of present and future disposal facilities

Evaluating potentials for future generation off-shore wind-power outside Norway

Science.gov (United States)

Benestad, R. E.; Haugen, J.; Haakenstad, H.

2012-12-01

With todays critical need of renewable energy sources, it is naturally to look towards wind power. With the long coast of Norway, there is a large potential for wind farms offshore Norway. Although there are more challenges with offshore wind energy installations compared to wind farms on land, the offshore wind is generally higher, and there is also higher persistence of wind speed values in the power generating classes. I planning offshore wind farms, there is a need of evaluation of the wind resources, the wind climatology and possible future changes. In this aspect, we use data from regional climate model runs performed in the European ENSEMBLE-project (van der Linden and J.F.B. Mitchell, 2009). In spite of increased reliability in RCMs in the recent years, the simulations still suffer from systematic model errors, therefore the data has to be corrected before using them in wind resource analyses. In correcting the wind speeds from the RCMs, we will use wind speeds from a Norwegian high resolution wind- and wave- archive, NORA10 (Reistad et al 2010), to do quantile mapping (Themeβl et. al. 2012). The quantile mapping is performed individually for each regional simulation driven by ERA40-reanalysis from the ENSEMBLE-project corrected against NORA10. The same calibration is then used to the belonging regional climate scenario. The calibration is done for each grid cell in the domain and for each day of the year centered in a +/-15 day window to make an empirical cumulative density function for each day of the year. The quantile mapping of the scenarios provide us with a new wind speed data set for the future, more correct compared to the raw ENSEMBLE scenarios. References: Reistad M., Ø. Breivik, H. Haakenstad, O. J. Aarnes, B. R. Furevik and J-R Bidlo, 2010, A high-resolution hindcast of wind and waves for The North Sea, The Norwegian Sea and The Barents Sea. J. Geophys. Res., 116. doi:10.1029/2010JC006402. Themessl M. J., A. Gobiet and A. Leuprecht, 2012

Fear of negative evaluation biases social evaluation inference: evidence from a probabilistic learning task.

Science.gov (United States)

Button, Katherine S; Kounali, Daphne; Stapinski, Lexine; Rapee, Ronald M; Lewis, Glyn; Munafò, Marcus R

2015-01-01

Fear of negative evaluation (FNE) defines social anxiety yet the process of inferring social evaluation, and its potential role in maintaining social anxiety, is poorly understood. We developed an instrumental learning task to model social evaluation learning, predicting that FNE would specifically bias learning about the self but not others. During six test blocks (3 self-referential, 3 other-referential), participants (n = 100) met six personas and selected a word from a positive/negative pair to finish their social evaluation sentences "I think [you are / George is]…". Feedback contingencies corresponded to 3 rules, liked, neutral and disliked, with P[positive word correct] = 0.8, 0.5 and 0.2, respectively. As FNE increased participants selected fewer positive words (β = -0.4, 95% CI -0.7, -0.2, p = 0.001), which was strongest in the self-referential condition (FNE × condition 0.28, 95% CI 0.01, 0.54, p = 0.04), and the neutral and dislike rules (FNE × condition × rule, p = 0.07). At low FNE the proportion of positive words selected for self-neutral and self-disliked greatly exceeded the feedback contingency, indicating poor learning, which improved as FNE increased. FNE is associated with differences in processing social-evaluative information specifically about the self. At low FNE this manifests as insensitivity to learning negative self-referential evaluation. High FNE individuals are equally sensitive to learning positive or negative evaluation, which although objectively more accurate, may have detrimental effects on mental health.

Role of nuclear fusion in future energy systems and the environment under future uncertainties

International Nuclear Information System (INIS)

Tokimatsu, Koji; Fujino, Jun'ichi; Konishi, Satoshi; Ogawa, Yuichi; Yamaji, Kenji

2003-01-01

Debates about whether or not to invest heavily in nuclear fusion as a future innovative energy option have been made within the context of energy technology development strategies. This is because the prospects for nuclear fusion are quite uncertain and the investments therefore carry the risk of quite large regrets, even though investment is needed in order to develop the technology. The timeframe by which nuclear fusion could become competitive in the energy market has not been adequately studied, nor has roles of the nuclear fusion in energy systems and the environment. The present study has two objectives. One is to reveal the conditions under which nuclear fusion could be introduced economically (hereafter, we refer to such introductory conditions as breakeven prices) in future energy systems. The other objective is to evaluate the future roles of nuclear fusion in energy systems and in the environment. Here we identify three roles that nuclear fusion will take on when breakeven prices are achieved: (i) a portion of the electricity market in 2100, (ii) reduction of annual global total energy systems cost, and (iii) mitigation of carbon tax (shadow price of carbon) under CO 2 constraints. Future uncertainties are key issues in evaluating nuclear fusion. Here we treated the following uncertainties: energy demand scenarios, introduction timeframe for nuclear fusion, capacity projections of nuclear fusion, CO 2 target in 2100, capacity utilization ratio of options in energy/environment technologies, and utility discount rates. From our investigations, we conclude that the presently designed nuclear fusion reactors may be ready for economical introduction into energy systems beginning around 2050-2060, and we can confirm that the favorable introduction of the reactors would reduce both the annual energy systems cost and the carbon tax (the shadow price of carbon) under a CO 2 concentration constraint

Ethics Beyond Finitude: Responsibility towards Future Generations and Nuclear Waste Management

Energy Technology Data Exchange (ETDEWEB)

Loefquist, Lars

2008-05-15

This dissertation has three aims: 1. To evaluate several ethical theories about responsibility towards future generations. 2. To construct a theory about responsibility towards future generations. 3. To carry out an ethical evaluation of different nuclear waste management methods. Five theories are evaluated with the help of evaluative criteria, primarily: A theory must provide future generations with some independent moral status. A theory should acknowledge moral pluralism. A theory should provide some normative claims about real-world problems. Derek Parfit's theory provides future generations with full moral status. But it is incompatible with moral pluralism, and does not provide reasonable normative claims about real-world problems. Brian Barry's theory provides such claims and a useful idea about risk management, but it does not provide an argument why future generations ought to exist. Avner de-Shalit's theory explains why they ought to exist; however, his theory can not easily explain why we ought to care for other people than those in our own community. Emmanuel Agius' theory gives an ontological explanation for mankind's unity, but reduces conflicts of interests to a common good. Finally, Hans Jonas' theory shifts the focus from the situation of future generations to the preconditions of human life generally. However, his theory presupposes a specific ontology, which might be unable to motivate people to act. The concluding chapters describe a narrative theory of responsibility. It claims that we should comprehend ourselves as parts of the common story of mankind and that we ought to provide future generations with equal opportunities. This implies that we should avoid transferring risks and focus on reducing the long-term risks associated with the nuclear waste

Integrated DEA models and grey system theory to evaluate past-to-future performance: a case of Indian electricity industry.

Science.gov (United States)

Wang, Chia-Nan; Nguyen, Nhu-Ty; Tran, Thanh-Tuyen

2015-01-01

The growth of economy and population together with the higher demand in energy has created many concerns for the Indian electricity industry whose capacity is at 211 gigawatts mostly in coal-fired plants. Due to insufficient fuel supply, India suffers from a shortage of electricity generation, leading to rolling blackouts; thus, performance evaluation and ranking the industry turn into significant issues. By this study, we expect to evaluate the rankings of these companies under control of the Ministry of Power. Also, this research would like to test if there are any significant differences between the two DEA models: Malmquist nonradial and Malmquist radial. Then, one advance model of MPI would be chosen to see these companies' performance in recent years and next few years by using forecasting results of Grey system theory. Totally, the realistic data 14 are considered to be in this evaluation after the strict selection from the whole industry. The results found that all companies have not shown many abrupt changes on their scores, and it is always not consistently good or consistently standing out, which demonstrated the high applicable usability of the integrated methods. This integrated numerical research gives a better "past-present-future" insights into performance evaluation in Indian electricity industry.

Impact of a future H

NARCIS (Netherlands)

Popa, M.E.; Segers, A.J.; Denier van der Gon, H.A.C.; Krol, M.C.; Visschedijk, A.J.H.; Schaap, M.; Röckmann, T.

2015-01-01

Hydrogen (H2) is being explored as a fuel for passenger vehicles; it can be used in fuel cells to power electric motors or burned in internal combustion engines. In order to evaluate the potential influence of a future H2-based road transportation on the regional air quality in Europe, we

Futures Brokerages Face uncertain Future

Institute of Scientific and Technical Information of China (English)

WANG PEI

2006-01-01

@@ 2005 was a quiet year for China's futures market.After four new trading products, including cotton, fuel oil and corn, were launched on the market in 2004, the development of the market seemed to stagnate. The trade value of the futures market totaled 13.4 trillion yuan (US$ 1.67 trillion) in 2005, down 8.5 percent year-on-year. Although the decrease is quite small and the trade value was still the second highest in the market's history, the majority of futures brokerage firms were running in the red. In some areas, up to 80 percent of futures companies made losses.

Shelf-life and quality evaluation of clementine following a combined treatment with γ-irradiation

International Nuclear Information System (INIS)

Mahrouz, M.; Lacroix, M.; D'Aprano, G.; Oufedjikh, H.; Boubekri, C.

2004-01-01

In order to enhance the shelf-life of a late variety of Moroccan Citrus clementina (Nour), ionizing treatments were applied at 0.3 kGy, as well as washing (cold water) and waxing treatments. It has been found that, despite the irradiation treatment, the washing and waxing treatment do not improve the quality of C. clementina, but rather result in peel injury. Finally, sensory evaluation confirmed that irradiation had no detrimental effect on the quality of clementines

Preliminary design of CERN Future Circular Collider tunnel: first evaluation of the radiation environment in critical areas for electronics

Science.gov (United States)

Infantino, Angelo; Alía, Rubén García; Besana, Maria Ilaria; Brugger, Markus; Cerutti, Francesco

2017-09-01

As part of its post-LHC high energy physics program, CERN is conducting a study for a new proton-proton collider, called Future Circular Collider (FCC-hh), running at center-of-mass energies of up to 100 TeV in a new 100 km tunnel. The study includes a 90-350 GeV lepton collider (FCC-ee) as well as a lepton-hadron option (FCC-he). In this work, FLUKA Monte Carlo simulation was extensively used to perform a first evaluation of the radiation environment in critical areas for electronics in the FCC-hh tunnel. The model of the tunnel was created based on the original civil engineering studies already performed and further integrated in the existing FLUKA models of the beam line. The radiation levels in critical areas, such as the racks for electronics and cables, power converters, service areas, local tunnel extensions was evaluated.

Preliminary design of CERN Future Circular Collider tunnel: first evaluation of the radiation environment in critical areas for electronics

Directory of Open Access Journals (Sweden)

Infantino Angelo

2017-01-01

Full Text Available As part of its post-LHC high energy physics program, CERN is conducting a study for a new proton-proton collider, called Future Circular Collider (FCC-hh, running at center-of-mass energies of up to 100 TeV in a new 100 km tunnel. The study includes a 90-350 GeV lepton collider (FCC-ee as well as a lepton-hadron option (FCC-he. In this work, FLUKA Monte Carlo simulation was extensively used to perform a first evaluation of the radiation environment in critical areas for electronics in the FCC-hh tunnel. The model of the tunnel was created based on the original civil engineering studies already performed and further integrated in the existing FLUKA models of the beam line. The radiation levels in critical areas, such as the racks for electronics and cables, power converters, service areas, local tunnel extensions was evaluated.

The clean energy future of Saskatchewan. Evaluating the potential for nuclear power in Saskatchewan

Energy Technology Data Exchange (ETDEWEB)

Harry, I. [SaskPower, Clean Energy Group, Regina, Saskatchewan (Canada)

2013-07-01

The clean energy direction of Saskatchewan is very dependent on the vision of the energy future. Saskatchewan has depended strongly on coal as a base load asset and embracing the future will depend on creating multiple pathways. This presentation will explore the pathways and the reasons why they are important.

Impact of a future H

NARCIS (Netherlands)

Popa, M.E.; Segers, A.J.; Denier van der Gon, H.A.C.; Krol, M.C.; Visschedijk, A.J.H.; Schaap, M.; Röckmann, T.

2015-01-01

Hydrogen (H₂) is being explored as a fuel for passenger vehicles; it can be used in fuel cells to power electric motors or burned in internal combustion engines. In order to evaluate the potential influence of a future H₂-based road transportation on the regional air quality

State-of-the-art for evaluating the potential impact of flooding on a radioactive waste repository

International Nuclear Information System (INIS)

1980-01-01

This report is a review of the state-of-the-art for evaluating the potential impact of flooding on a deep radioactive-waste repository, namely, for predicting the future occurrence of catastrophic flooding and for estimating the effect of such flooding on waste containment characteristics. Several detrimental effects are identified: flooding can increase groundwater seepage velocities through a repository within the framework of the existing hydrologic system and thus increase the rate of radioactive-waste leakage to the biosphere; flooding may alter repository hydrology by reversing flow gradients, relocating sources of groundwater recharge and discharge, or shortening seepage paths, thereby producing unpredictable leakage; saturation of a vadose-zone repository during flooding can increase groundwater seepage velocities by several orders of magnitude; and flooding can damage repository-media containment properties by inducing seismic or chemical instability or increasing fracture permeability in relatively shallow repository rock as a result of redistributing in-situ stresses. Short-term flooding frequency and magnitude can be predicted statistically by analyzing historical records of flooding. However, long-term flooding events that could damage a permanent repository cannot be predicted with confidence because the geologic record is neither unique nor sufficienly complete for statistical analysis. It is more important to identify parameters characterizing containment properties (such as permeability, groundwater gradient, and shortest seepage path length to the biosphere) that could be affected by future flooding, estimate the maximum magnitude of flooding that could occur within the life of the repository by examining the geologic record, and determine the impact such flooding could have on the parameter values

Characterizing drought stress and trait influence on maize yield under current and future conditions.

Science.gov (United States)

Harrison, Matthew T; Tardieu, François; Dong, Zhanshan; Messina, Carlos D; Hammer, Graeme L

2014-03-01

Global climate change is predicted to increase temperatures, alter geographical patterns of rainfall and increase the frequency of extreme climatic events. Such changes are likely to alter the timing and magnitude of drought stresses experienced by crops. This study used new developments in the classification of crop water stress to first characterize the typology and frequency of drought-stress patterns experienced by European maize crops and their associated distributions of grain yield, and second determine the influence of the breeding traits anthesis-silking synchrony, maturity and kernel number on yield in different drought-stress scenarios, under current and future climates. Under historical conditions, a low-stress scenario occurred most frequently (ca. 40%), and three other stress types exposing crops to late-season stresses each occurred in ca. 20% of cases. A key revelation shown was that the four patterns will also be the most dominant stress patterns under 2050 conditions. Future frequencies of low drought stress were reduced by ca. 15%, and those of severe water deficit during grain filling increased from 18% to 25%. Despite this, effects of elevated CO2 on crop growth moderated detrimental effects of climate change on yield. Increasing anthesis-silking synchrony had the greatest effect on yield in low drought-stress seasonal patterns, whereas earlier maturity had the greatest effect in crops exposed to severe early-terminal drought stress. Segregating drought-stress patterns into key groups allowed greater insight into the effects of trait perturbation on crop yield under different weather conditions. We demonstrate that for crops exposed to the same drought-stress pattern, trait perturbation under current climates will have a similar impact on yield as that expected in future, even though the frequencies of severe drought stress will increase in future. These results have important ramifications for breeding of maize and have implications for

Evaluation of future policy instruments - Sub-Project 2; Utvaerdering av framtida styrmedel - Delprojekt 2 inom projektet Perspektiv paa framtida avfallsbehandling

Energy Technology Data Exchange (ETDEWEB)

Bisaillon, Mattias; Dahlen, Lisa; Detterfelt, Lia; Edner, Stig; Toren, Johan

2013-09-01

There are several recently introduced and future possible policy instruments that are of great interest to study in order to understand the future for the Swedish waste treatment market. In the energy sector, the use of system analysis models has proven to be effective in order to understand the effects and consequences of policy instruments. In the waste sector, however, such analyses have only been conducted sporadically. This in spite of the introduction of highly influential policy instruments such as producer responsibility, landfill tax and landfill ban, which together have contributed to landfilling of Swedish household waste practically has ceased. The goal of this project was, by using system analysis models, to study and evaluate the newly introduced and future possible policy instruments which affect Swedish waste treatment. The assessment was made in terms of how policy instruments affect: - the distribution of treatment technologies, - waste amounts, - greenhouse gas emissions and - the economics of waste treatment. The project was performed during 2011 and 2012 as a part of the research project 'Perspectives on sustainable waste treatment (PFA)'. During the project, discussions have taken place within the working group and the reference group on which instruments are most interesting and relevant to study. Furthermore, opinions have been gathered from the association Swedish Waste Managements policy instrument group and from various players in the industry at conferences, presentations and workshops.

The Finnis River. A natural laboratory of mining impact- past, present and future

International Nuclear Information System (INIS)

Markich, S.J.; Jeffree, R.A.

2002-03-01

The Rum Jungle uranium-copper mine in tropical northern Australia has been a source of acid rock drainage contaminants since the 1950s, which have had adverse impacts on the receiving waters of the Finniss River. Mine site remediation began in 1982 followed by long-term monitoring of water quality and flow, based on daily measurements within the Finniss River system. A decade or more after the initiation of these remedial activities, a set of investigations have been completed that have measured the post-remedial ecological status of the Finniss River system, relative to this environmental benchmark. These studies have also been complemented by studies on various other ecological endpoints. Moreover, the Finniss River system has provided unique opportunities for broader scientific goals to be pursued. Because it has been so well-monitored, it can be viewed as a natural laboratory to investigate the impacts of acid rock drainage on tropical freshwater biodiversity. The scientific papers presented at this symposium address a broad spectrum of issues that are directly related to environmental sustainability and mining. The topics range across future contaminant scenarios and their predicted ecological impacts, the various metrics used to assess ecological detriment to biodiversity, the abilities of laminated biological structures to act as archives of pollution history, and also spin-off applications in environmental and wildlife management. Furthermore, the participation of many stakeholders in open discussion during the symposium provided an important set of views and opinions on the needs for future studies in the Finniss River system

The Finnis River. A natural laboratory of mining impact- past, present and future

Energy Technology Data Exchange (ETDEWEB)

Markich, S J; Jeffree, R A [eds.

2002-03-01

The Rum Jungle uranium-copper mine in tropical northern Australia has been a source of acid rock drainage contaminants since the 1950s, which have had adverse impacts on the receiving waters of the Finniss River. Mine site remediation began in 1982 followed by long-term monitoring of water quality and flow, based on daily measurements within the Finniss River system. A decade or more after the initiation of these remedial activities, a set of investigations have been completed that have measured the post-remedial ecological status of the Finniss River system, relative to this environmental benchmark. These studies have also been complemented by studies on various other ecological endpoints. Moreover, the Finniss River system has provided unique opportunities for broader scientific goals to be pursued. Because it has been so well-monitored, it can be viewed as a natural laboratory to investigate the impacts of acid rock drainage on tropical freshwater biodiversity. The scientific papers presented at this symposium address a broad spectrum of issues that are directly related to environmental sustainability and mining. The topics range across future contaminant scenarios and their predicted ecological impacts, the various metrics used to assess ecological detriment to biodiversity, the abilities of laminated biological structures to act as archives of pollution history, and also spin-off applications in environmental and wildlife management. Furthermore, the participation of many stakeholders in open discussion during the symposium provided an important set of views and opinions on the needs for future studies in the Finniss River system.

The new natural gas futures market - is it efficient?

International Nuclear Information System (INIS)

Herbert, J.H.

1993-01-01

Aspects of the natural gas futures market are discussed. In particular, the efficiency of the natural gas futures market is evaluated using a regression equation. It is found that the market has behaved more like an inefficient market than an efficient one. A variety of tests are applied to the estimated equation. These tests suggest that the estimated equation provides a good summary of the relationship between spot and futures prices for the time period. In addition, the equation is found to produce accurate forecasts. (Author)

A dozen years of American Academy of Sleep Medicine (AASM) International Mini-Fellowship: program evaluation and future directions.

Science.gov (United States)

Ioachimescu, Octavian C; Wickwire, Emerson M; Harrington, John; Kristo, David; Arnedt, J Todd; Ramar, Kannan; Won, Christine; Billings, Martha E; DelRosso, Lourdes; Williams, Scott; Paruthi, Shalini; Morgenthaler, Timothy I

2014-03-15

Sleep medicine remains an underrepresented medical specialty worldwide, with significant geographic disparities with regard to training, number of available sleep specialists, sleep laboratory or clinic infrastructures, and evidence-based clinical practices. The American Academy of Sleep Medicine (AASM) is committed to facilitating the education of sleep medicine professionals to ensure high-quality, evidence-based clinical care and improve access to sleep centers around the world, particularly in developing countries. In 2002, the AASM launched an annual 4-week training program called Mini-Fellowship for International Scholars, designed to support the establishment of sleep medicine in developing countries. The participating fellows were generally chosen from areas that lacked a clinical infrastructure in this specialty and provided with training in AASM Accredited sleep centers. This manuscript presents an overview of the program, summarizes the outcomes, successes, and lessons learned during the first 12 years, and describes a set of programmatic changes for the near-future, as assembled and proposed by the AASM Education Committee and recently approved by the AASM Board of Directors. Ioachimescu OC; Wickwire EM; Harrington J; Kristo D; Arnedt JT; Ramar K; Won C; Billings ME; DelRosso L; Williams S; Paruthi S; Morgenthaler TI. A dozen years of American Academy of Sleep Medicine (AASM) international mini-fellowship: program evaluation and future directions.

Fear of Negative Evaluation Biases Social Evaluation Inference: Evidence from a Probabilistic Learning Task

Science.gov (United States)

Button, Katherine S.; Kounali, Daphne; Stapinski, Lexine; Rapee, Ronald M.; Lewis, Glyn; Munafò, Marcus R.

2015-01-01

Background Fear of negative evaluation (FNE) defines social anxiety yet the process of inferring social evaluation, and its potential role in maintaining social anxiety, is poorly understood. We developed an instrumental learning task to model social evaluation learning, predicting that FNE would specifically bias learning about the self but not others. Methods During six test blocks (3 self-referential, 3 other-referential), participants (n = 100) met six personas and selected a word from a positive/negative pair to finish their social evaluation sentences “I think [you are / George is]…”. Feedback contingencies corresponded to 3 rules, liked, neutral and disliked, with P[positive word correct] = 0.8, 0.5 and 0.2, respectively. Results As FNE increased participants selected fewer positive words (β = −0.4, 95% CI −0.7, −0.2, p = 0.001), which was strongest in the self-referential condition (FNE × condition 0.28, 95% CI 0.01, 0.54, p = 0.04), and the neutral and dislike rules (FNE × condition × rule, p = 0.07). At low FNE the proportion of positive words selected for self-neutral and self-disliked greatly exceeded the feedback contingency, indicating poor learning, which improved as FNE increased. Conclusions FNE is associated with differences in processing social-evaluative information specifically about the self. At low FNE this manifests as insensitivity to learning negative self-referential evaluation. High FNE individuals are equally sensitive to learning positive or negative evaluation, which although objectively more accurate, may have detrimental effects on mental health. PMID:25853835

Evaluating the benefits of an electrical energy storage system in a future smart grid

International Nuclear Information System (INIS)

Wade, N.S.; Taylor, P.C.; Lang, P.D.; Jones, P.R.

2010-01-01

Interest in electrical energy storage systems is increasing as the opportunities for their application become more compelling in an industry with a back-drop of ageing assets, increasing distributed generation and a desire to transform networks into Smart Grids. A field trial of an energy storage system designed and built by ABB is taking place on a section of 11 kV distribution network operated by EDF Energy Networks in Great Britain. This paper reports on the findings from simulation software developed at Durham University that evaluates the benefits brought by operating an energy storage system in response to multiple events on multiple networks. The tool manages the allocation of a finite energy resource to achieve the most beneficial shared operation across two adjacent areas of distribution network. Simulations account for the key energy storage system parameters of capacity and power rating. Results for events requiring voltage control and power flow management show how the choice of operating strategy influences the benefits achieved. The wider implications of these results are discussed to provide an assessment of the role of electrical energy storage systems in future Smart Grids.

A New Framework to Evaluate Urban Design Using Urban Microclimatic Modeling in Future Climatic Conditions

Directory of Open Access Journals (Sweden)

Dasaraden Mauree

2018-04-01

Full Text Available Building more energy-efficient and sustainable urban areas that will both mitigate the effects of climate change and anticipate living conditions in future climate scenarios requires the development of new tools and methods that can help urban planners, architects and communities achieve this goal. In the current study, we designed a workflow that links different methodologies developed separately, to derive the energy consumption of a university school campus for the future. Three different scenarios for typical future years (2039, 2069, 2099 were run, as well as a renovation scenario (Minergie-P. We analyzed the impact of climate change on the heating and cooling demand of buildings and determined the relevance of taking into account the local climate in this particular context. The results from the simulations confirmed that in the future, there will be a constant decrease in the heating demand, while the cooling demand will substantially increase. Significantly, it was further demonstrated that when the local urban climate was taken into account, there was an even higher rise in the cooling demand, but also that a set of proposed Minergie-P renovations were not sufficient to achieve resilient buildings. We discuss the implication of this work for the simulation of building energy consumption at the neighborhood scale and the impact of future local climate on energy system design. We finally give a few perspectives regarding improved urban design and possible pathways for future urban areas.

Lessons from two high CO2 worlds - future oceans and intensive aquaculture.

Science.gov (United States)

Ellis, Robert P; Urbina, Mauricio A; Wilson, Rod W

2017-06-01

Exponentially rising CO 2 (currently ~400 μatm) is driving climate change and causing acidification of both marine and freshwater environments. Physiologists have long known that CO 2 directly affects acid-base and ion regulation, respiratory function and aerobic performance in aquatic animals. More recently, many studies have demonstrated that elevated CO 2 projected for end of this century (e.g. 800-1000 μatm) can also impact physiology, and have substantial effects on behaviours linked to sensory stimuli (smell, hearing and vision) both having negative implications for fitness and survival. In contrast, the aquaculture industry was farming aquatic animals at CO 2 levels that far exceed end-of-century climate change projections (sometimes >10 000 μatm) long before the term 'ocean acidification' was coined, with limited detrimental effects reported. It is therefore vital to understand the reasons behind this apparent discrepancy. Potential explanations include 1) the use of 'control' CO 2 levels in aquaculture studies that go beyond 2100 projections in an ocean acidification context; 2) the relatively benign environment in aquaculture (abundant food, disease protection, absence of predators) compared to the wild; 3) aquaculture species having been chosen due to their natural tolerance to the intensive conditions, including CO 2 levels; or 4) the breeding of species within intensive aquaculture having further selected traits that confer tolerance to elevated CO 2 . We highlight this issue and outline the insights that climate change and aquaculture science can offer for both marine and freshwater settings. Integrating these two fields will stimulate discussion on the direction of future cross-disciplinary research. In doing so, this article aimed to optimize future research efforts and elucidate effective mitigation strategies for managing the negative impacts of elevated CO 2 on future aquatic ecosystems and the sustainability of fish and shellfish

Harvesting interacts with climate change to affect future habitat quality of a focal species in eastern Canada's boreal forest.

Science.gov (United States)

Tremblay, Junior A; Boulanger, Yan; Cyr, Dominic; Taylor, Anthony R; Price, David T; St-Laurent, Martin-Hugues

2018-01-01

Many studies project future bird ranges by relying on correlative species distribution models. Such models do not usually represent important processes explicitly related to climate change and harvesting, which limits their potential for predicting and understanding the future of boreal bird assemblages at the landscape scale. In this study, we attempted to assess the cumulative and specific impacts of both harvesting and climate-induced changes on wildfires and stand-level processes (e.g., reproduction, growth) in the boreal forest of eastern Canada. The projected changes in these landscape- and stand-scale processes (referred to as "drivers of change") were then assessed for their impacts on future habitats and potential productivity of black-backed woodpecker (BBWO; Picoides arcticus), a focal species representative of deadwood and old-growth biodiversity in eastern Canada. Forest attributes were simulated using a forest landscape model, LANDIS-II, and were used to infer future landscape suitability to BBWO under three anthropogenic climate forcing scenarios (RCP 2.6, RCP 4.5 and RCP 8.5), compared to the historical baseline. We found climate change is likely to be detrimental for BBWO, with up to 92% decline in potential productivity under the worst-case climate forcing scenario (RCP 8.5). However, large declines were also projected under baseline climate, underlining the importance of harvest in determining future BBWO productivity. Present-day harvesting practices were the single most important cause of declining areas of old-growth coniferous forest, and hence appeared as the single most important driver of future BBWO productivity, regardless of the climate scenario. Climate-induced increases in fire activity would further promote young, deciduous stands at the expense of old-growth coniferous stands. This suggests that the biodiversity associated with deadwood and old-growth boreal forests may be greatly altered by the cumulative impacts of natural and

Harvesting interacts with climate change to affect future habitat quality of a focal species in eastern Canada's boreal forest.

Directory of Open Access Journals (Sweden)

Junior A Tremblay

Full Text Available Many studies project future bird ranges by relying on correlative species distribution models. Such models do not usually represent important processes explicitly related to climate change and harvesting, which limits their potential for predicting and understanding the future of boreal bird assemblages at the landscape scale. In this study, we attempted to assess the cumulative and specific impacts of both harvesting and climate-induced changes on wildfires and stand-level processes (e.g., reproduction, growth in the boreal forest of eastern Canada. The projected changes in these landscape- and stand-scale processes (referred to as "drivers of change" were then assessed for their impacts on future habitats and potential productivity of black-backed woodpecker (BBWO; Picoides arcticus, a focal species representative of deadwood and old-growth biodiversity in eastern Canada. Forest attributes were simulated using a forest landscape model, LANDIS-II, and were used to infer future landscape suitability to BBWO under three anthropogenic climate forcing scenarios (RCP 2.6, RCP 4.5 and RCP 8.5, compared to the historical baseline. We found climate change is likely to be detrimental for BBWO, with up to 92% decline in potential productivity under the worst-case climate forcing scenario (RCP 8.5. However, large declines were also projected under baseline climate, underlining the importance of harvest in determining future BBWO productivity. Present-day harvesting practices were the single most important cause of declining areas of old-growth coniferous forest, and hence appeared as the single most important driver of future BBWO productivity, regardless of the climate scenario. Climate-induced increases in fire activity would further promote young, deciduous stands at the expense of old-growth coniferous stands. This suggests that the biodiversity associated with deadwood and old-growth boreal forests may be greatly altered by the cumulative impacts of

Future Directions in the Study of Close Relationships: Conflict is Bad (Except When It’s Not)

Science.gov (United States)

Laursen, Brett; Hafen, Christopher

2009-01-01

Beneficial and detrimental correlates of interpersonal disagreement have been postulated and documented. The conclusion: Conflict is both bad and good. The evidence for these paradoxical effects is summarized. In this essay, we argue that the consequences of conflict for individuals depends on its frequency, the way in which it is managed, and the quality of the relationship in which it arises. Nonlinear patterns of association are hypothesized such that constructive conflicts, particularly those arising in supportive relationships, should (up to a limit) predict more beneficial and fewer detrimental outcomes. In contrast, coercive conflicts, particularly those arising in unsupportive relationships, should predict more adverse and fewer favorable outcomes. PMID:20953335

The Pricing and Efficiency of Australian Treasury Bond Futures

Directory of Open Access Journals (Sweden)

Alex Frino

2014-06-01

Full Text Available This paper examines the efficiency of the Treasury Bond futures market in Australia. We provide a comprehensive explanation of the method used to price, and evaluate efficiency of the 3 and 10 Year Australian Treasury Bond Futures contracts, against underlying bond baskets. Results indicate that the futures contracts exhibit minimal variation from their theoretical value. The average mispricing equates to 1.96 basis points for 3 Year and 1.19 basis points for 10 Year government bond futures contracts. However, during some periods (including the financial crisis of 2008, the bond futures contracts exhibit greater mispricing. Consistent with prior literature, we find a decreasing pattern of mispricing towards expiry, with the futures contract yields and average forward yields of the underlying bonds converging towards expiry. Further analysis reveals that volatility and time to expiry exhibit a significant positive relationship with the absolute level of mispricing.

Future rainfall variations reduce abundances of aboveground arthropods in model agroecosystems with different soil types

Directory of Open Access Journals (Sweden)

Johann G. Zaller

2014-10-01

Full Text Available Climate change scenarios for Central Europe predict less frequent but heavier rainfalls and longer drought periods during the growing season. This is expected to alter arthropods in agroecosystems that are important as biocontrol agents, herbivores or food for predators (e.g. farmland birds. In a lysimeter facility (totally 18 3-m2-plots, we experimentally tested the effects of long-term past vs. prognosticated future rainfall variations (15% increased rainfall per event, 25% more dry days according to regionalized climate change models from the Intergovernmental Panel on Climate Change (IPCC on aboveground arthropods in winter wheat (Triticum aestivum L. cultivated at three different soil types (calcaric phaeozem, calcic chernozem and gleyic phaeozem. Soil types were established 17 years and rainfall treatments one month before arthropod sampling; treatments were fully crossed and replicated three times. Aboveground arthropods were assessed by suction sampling, their mean abundances (± SD differed between April, May and June with 20 ± 3 m-2, 90 ± 35 m-2 and 289 ± 93 individuals m-2, respectively. Averaged across sampling dates, future rainfall reduced the abundance of spiders (Araneae, -47%, cicadas and leafhoppers (Auchenorrhyncha, -39%, beetles (Coleoptera, -52%, ground beetles (Carabidae, -41%, leaf beetles (Chrysomelidae, -64%, spring tails (Collembola, -58%, flies (Diptera, -73% and lacewings (Neuroptera, -73% but increased the abundance of snails (Gastropoda, +69%. Across sampling dates, soil types had no effects on arthropod abundances. Arthropod diversity was neither affected by rainfall nor soil types. Arthropod abundance was positively correlated with weed biomass for almost all taxa; abundance of Hemiptera and of total arthropods was positively correlated with weed density. These detrimental effects of future rainfall varieties on arthropod taxa in wheat fields can potentially alter arthropod-associated agroecosystem services.

Barefoot running: an evaluation of current hypothesis, future research and clinical applications.

Science.gov (United States)

Tam, Nicholas; Astephen Wilson, Janie L; Noakes, Timothy D; Tucker, Ross

2014-03-01

Barefoot running has become a popular research topic, driven by the increasing prescription of barefoot running as a means of reducing injury risk. Proponents of barefoot running cite evolutionary theories that long-distance running ability was crucial for human survival, and proof of the benefits of natural running. Subsequently, runners have been advised to run barefoot as a treatment mode for injuries, strength and conditioning. The body of literature examining the mechanical, structural, clinical and performance implications of barefoot running is still in its infancy. Recent research has found significant differences associated with barefoot running relative to shod running, and these differences have been associated with factors that are thought to contribute to injury and performance. Crucially, long-term prospective studies have yet to be conducted and the link between barefoot running and injury or performance remains tenuous and speculative. The injury prevention potential of barefoot running is further complicated by the complexity of injury aetiology, with no single factor having been identified as causative for the most common running injuries. The aim of the present review was to critically evaluate the theory and evidence for barefoot running, drawing on both collected evidence as well as literature that have been used to argue in favour of barefoot running. We describe the factors driving the prescription of barefoot running, examine which of these factors may have merit, what the collected evidence suggests about the suitability of barefoot running for its purported uses and describe the necessary future research to confirm or refute the barefoot running hypotheses.

Characterizing costs and benefits of uncertain future regulatory requirements on the U.S. natural gas industry

International Nuclear Information System (INIS)

Godec, M.L.; Smith, G.E.; Fitzgibbon, T.

1995-01-01

Environmental regulatory requirements at both the state and federal level are constantly changing, making it difficult for industry and R ampersand D program managers to project future compliance requirements and costs. Even if a company is trying to keep abreast of various proposed regulatory initiatives, the number of possible combinations of initiatives that could occur in the future seems virtually limitless. Uncertainty associated with potential future environmental compliance requirements makes the identification and evaluation of future investment and R ampersand D opportunities exceedingly difficult, and makes the process of systematic strategic planning increasingly complex. This paper describes a methodology for accounting for uncertain future environmental compliance costs in a systematic, comprehensive manner. Through analysis of proposed initiatives for making future environmental requirements more stringent, forecasting the likelihood of occurrence and potential timing of each initiative, and estimating potential future compliance costs associated with each initiative, a thorough process for incorporating regulatory uncertainty into strategic planning and project evaluation is described. This approach can be used for evaluating R ampersand D opportunities to determine where development of new technologies or assessment of risks posed by industry operations may have the greatest impact on future industry costs of compliance. This approach could also be used to account for the uncertainty of future environmental costs in corporate strategic planning or for factoring future compliance costs into project evaluation. This approach could also be enhanced through use in conjunction with other modeling and forecasting systems that could consider a broad range of impacts, including impacts on gas production, industry activity levels, and tax revenues

Future Arctic marine access: analysis and evaluation of observations, models, and projections of sea ice

Directory of Open Access Journals (Sweden)

T. S. Rogers

2013-02-01

Full Text Available There is an emerging need for regional applications of sea ice projections to provide more accuracy and greater detail to scientists, national, state and local planners, and other stakeholders. The present study offers a prototype for a comprehensive, interdisciplinary study to bridge observational data, climate model simulations, and user needs. The study's first component is an observationally based evaluation of Arctic sea ice trends during 1980–2008, with an emphasis on seasonal and regional differences relative to the overall pan-Arctic trend. Regional sea ice loss has varied, with a significantly larger decline of winter maximum (January–March extent in the Atlantic region than in other sectors. A lead–lag regression analysis of Atlantic sea ice extent and ocean temperatures indicates that reduced sea ice extent is associated with increased Atlantic Ocean temperatures. Correlations between the two variables are greater when ocean temperatures lag rather than lead sea ice. The performance of 13 global climate models is evaluated using three metrics to compare sea ice simulations with the observed record. We rank models over the pan-Arctic domain and regional quadrants and synthesize model performance across several different studies. The best performing models project reduced ice cover across key access routes in the Arctic through 2100, with a lengthening of seasons for marine operations by 1–3 months. This assessment suggests that the Northwest and Northeast Passages hold potential for enhanced marine access to the Arctic in the future, including shipping and resource development opportunities.

The future of building and living; Zukunft des Bauens und Wohnens

Energy Technology Data Exchange (ETDEWEB)

Scharp, Michael

2011-06-15

What is the future of building and living? The author of the contribution under cionsideration attempts to answer this question. Under this aspect, the author identifies general trends affecting the future of building and living using an Internet research, a literature review and the evaluation of research projects of the Institute for Futures Studies and Technology Assessment (Berlin, Federal Republic of Germany). The following priorities are considered: construction and living for the residential sector, socio-demographic developments, intelligent living, technology attitudes and building energy technology. Subsequently, the trends are evaluated and discussed at a workshop. The 32 identified trends range from the development of new residential construction, the needs of older generations, the use of a smart home solutions and the use of efficient heating systems.

Endocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects

Directory of Open Access Journals (Sweden)

Eva M Marco

2011-10-01

Full Text Available Public concern on mental health has noticeably increased given the high prevalence of neuropsychiatric disorders. Cognition and emotionality are the most affected functions in neuropsychiatric disorders, i.e. anxiety disorders, depression and schizophrenia. In this review, most relevant literature on the role of the endocannabinoid (eCB system in neuropsychiatric disorders will be presented. Evidence from clinical and animal studies is provided for the participation of CB1 and CB2 receptors (CB1R and CB2R in the above mentioned neuropsychiatric disorders. CBRs are crucial in some of the emotional and cognitive impairments reported, although more research is required to understand the specific role of the eCB system in neuropsychiatric disorders. Cannabidiol (CBD, the main non-psychotropic component of the Cannabis sativa plant, has shown therapeutic potential in several neuropsychiatric disorders. Although further studies are needed, recent studies indicate that CBD therapeutic effects may partially depend on facilitation of eCB-mediated neurotransmission. Last but not least, this review includes recent findings on the role of the eCB system in eating disorders. A deregulation of the eCB system has been proposed to be in the bases of several neuropsychiatric disorders, including eating disorders. Cannabis consumption has been related to the appearance of psychotic symptoms and schizophrenia. In contrast, the pharmacological manipulation of this eCB system has been proposed as a potential strategy for the treatment of anxiety disorders, depression, and anorexia nervosa. In conclusion, the eCB system plays a critical role in psychiatry; however, detrimental consequences of manipulating this endogenous system cannot be underestimated over the potential and promising perspectives of its therapeutic manipulation.

Corrosion behavior of Zircaloy 4 cladding material. Evaluation of the hydriding effect

International Nuclear Information System (INIS)

Blat, M.

1997-04-01

In this work, particular attention has been paid to the hydriding effect in PIE and laboratory test to validate a detrimental hydrogen contribution on Zircaloy 4 corrosion behavior at high burnup. Laboratory corrosion tests results confirm that hydrides have a detrimental role on corrosion kinetics. This effect is particularly significant for cathodic charged samples with a massive hydride outer layer before corrosion test. PIE show that at high burnup a hydride layer is formed underneath the metal/oxide interface. The results of the metallurgical examinations are discussed with respect to the possible mechanisms involved in this detrimental effect of hydrogen. Therefore, according to the laboratory tests results and PIE, hydrogen could be a strong contributor to explain the increase in corrosion rate at high burnup. (author)

Forecasting oil price movements with crack spread futures

International Nuclear Information System (INIS)

Murat, Atilim; Tokat, Ekin

2009-01-01

In oil markets, the crack spread refers to the crude-product price relationship. Refiners are major participants in oil markets and they are primarily exposed to the crack spread. In other words, refiner activity is substantially driven by the objective of protecting the crack spread. Moreover, oil consumers are active participants in the oil hedging market and they are frequently exposed to the crack spread. From another perspective, hedge funds are heavily using crack spread to speculate in oil markets. Based on the high volume of crack spread futures trading in oil markets, the question we want to raise is whether the crack spread futures can be a good predictor of oil price movements. We investigated first whether there is a causal relationship between the crack spread futures and the spot oil markets in a vector error correction framework. We found the causal impact of crack spread futures on spot oil market both in the long- and the short-run after April 2003 where we detected a structural break in the model. To examine the forecasting performance, we use the random walk model (RWM) as a benchmark, and we also evaluate the forecasting power of crack spread futures against the crude oil futures. The results showed that (a) both the crack spread futures and the crude oil futures outperformed the RWM; and (b) the crack spread futures are almost as good as the crude oil futures in predicting the movements in spot oil markets. (author)

Future shift of the relative roles of precipitation and temperature in controlling annual runoff in the conterminous United States

Directory of Open Access Journals (Sweden)

K. Duan

2017-11-01

Full Text Available This study examines the relative roles of climatic variables in altering annual runoff in the conterminous United States (CONUS in the 21st century, using a monthly ecohydrological model (the Water Supply Stress Index model, WaSSI driven with historical records and future scenarios constructed from 20 Coupled Model Intercomparison Project Phase 5 (CMIP5 climate models. The results suggest that precipitation has been the primary control of runoff variation during the latest decades, but the role of temperature will outweigh that of precipitation in most regions if future climate change follows the projections of climate models instead of the historical tendencies. Besides these two key factors, increasing air humidity is projected to partially offset the additional evaporative demand caused by warming and consequently enhance runoff. Overall, the projections from 20 climate models suggest a high degree of consistency on the increasing trends in temperature, precipitation, and humidity, which will be the major climatic driving factors accounting for 43–50, 20–24, and 16–23 % of the runoff change, respectively. Spatially, while temperature rise is recognized as the largest contributor that suppresses runoff in most areas, precipitation is expected to be the dominant factor driving runoff to increase across the Pacific coast and the southwest. The combined effects of increasing humidity and precipitation may also surpass the detrimental effects of warming and result in a hydrologically wetter future in the east. However, severe runoff depletion is more likely to occur in the central CONUS as temperature effect prevails.

Future shift of the relative roles of precipitation and temperature in controlling annual runoff in the conterminous United States

Science.gov (United States)

Duan, Kai; Sun, Ge; McNulty, Steven G.; Caldwell, Peter V.; Cohen, Erika C.; Sun, Shanlei; Aldridge, Heather D.; Zhou, Decheng; Zhang, Liangxia; Zhang, Yang

2017-11-01

This study examines the relative roles of climatic variables in altering annual runoff in the conterminous United States (CONUS) in the 21st century, using a monthly ecohydrological model (the Water Supply Stress Index model, WaSSI) driven with historical records and future scenarios constructed from 20 Coupled Model Intercomparison Project Phase 5 (CMIP5) climate models. The results suggest that precipitation has been the primary control of runoff variation during the latest decades, but the role of temperature will outweigh that of precipitation in most regions if future climate change follows the projections of climate models instead of the historical tendencies. Besides these two key factors, increasing air humidity is projected to partially offset the additional evaporative demand caused by warming and consequently enhance runoff. Overall, the projections from 20 climate models suggest a high degree of consistency on the increasing trends in temperature, precipitation, and humidity, which will be the major climatic driving factors accounting for 43-50, 20-24, and 16-23 % of the runoff change, respectively. Spatially, while temperature rise is recognized as the largest contributor that suppresses runoff in most areas, precipitation is expected to be the dominant factor driving runoff to increase across the Pacific coast and the southwest. The combined effects of increasing humidity and precipitation may also surpass the detrimental effects of warming and result in a hydrologically wetter future in the east. However, severe runoff depletion is more likely to occur in the central CONUS as temperature effect prevails.

Harvesting interacts with climate change to affect future habitat quality of a focal species in eastern Canada’s boreal forest

Science.gov (United States)

Boulanger, Yan; Cyr, Dominic; Taylor, Anthony R.; Price, David T.; St-Laurent, Martin-Hugues

2018-01-01

Many studies project future bird ranges by relying on correlative species distribution models. Such models do not usually represent important processes explicitly related to climate change and harvesting, which limits their potential for predicting and understanding the future of boreal bird assemblages at the landscape scale. In this study, we attempted to assess the cumulative and specific impacts of both harvesting and climate-induced changes on wildfires and stand-level processes (e.g., reproduction, growth) in the boreal forest of eastern Canada. The projected changes in these landscape- and stand-scale processes (referred to as “drivers of change”) were then assessed for their impacts on future habitats and potential productivity of black-backed woodpecker (BBWO; Picoides arcticus), a focal species representative of deadwood and old-growth biodiversity in eastern Canada. Forest attributes were simulated using a forest landscape model, LANDIS-II, and were used to infer future landscape suitability to BBWO under three anthropogenic climate forcing scenarios (RCP 2.6, RCP 4.5 and RCP 8.5), compared to the historical baseline. We found climate change is likely to be detrimental for BBWO, with up to 92% decline in potential productivity under the worst-case climate forcing scenario (RCP 8.5). However, large declines were also projected under baseline climate, underlining the importance of harvest in determining future BBWO productivity. Present-day harvesting practices were the single most important cause of declining areas of old-growth coniferous forest, and hence appeared as the single most important driver of future BBWO productivity, regardless of the climate scenario. Climate-induced increases in fire activity would further promote young, deciduous stands at the expense of old-growth coniferous stands. This suggests that the biodiversity associated with deadwood and old-growth boreal forests may be greatly altered by the cumulative impacts of natural and

Future Projection of Droughts over South Korea Using Representative Concentration Pathways (RCPs

Directory of Open Access Journals (Sweden)

Byung Sik Kim

2014-01-01

Full Text Available The Standardized Precipitation Index (SPI, a method widely used to analyze droughts related to climate change, does not consider variables related to temperature and is limited because it cannot consider changes in hydrological balance, such as evapotranspiration from climate change. If we were to consider only the future increase in precipitation from climate change, droughts may decrease. However, because usable water can diminish from an increase in evapotranspiration, it is important to research on projected droughts considering the amount of evapotranspiration along with projecting and evaluating potential droughts considering the impact of climate change. As such, this study evaluated the occurrence of droughts using the Standardized Precipitation Evapotranspiration Index (SPEI as a newly conceptualized drought index that is similar to SPI but includes the temperature variability. We extracted simulated future precipitation and temperature data (2011 - 2099 from the Representative Concentration Pathway (RCP climate change scenario of IPCC AR5 to evaluate the impact of future climate change on the occurrence of droughts of South Korea. We analyzed the ratio of evapotranspiration to precipitation of meteorological observatories nationwide. In addition, we calculated the SPEI related to drought in the process to evaluate the future occurrence of droughts of South Korea. To confirm validity of SPEI results, extreme indices were analyzed. This resulted in the notion that as we go further into the future, the precipitation increases. But because of an increase in evapotranspiration also from a rise in temperature and continued dryness, the severity of droughts is projected to exacerbate.

Nuclear Data Uncertainty Quantification: Past, Present and Future

International Nuclear Information System (INIS)

Smith, D.L.

2015-01-01

An historical overview is provided of the mathematical foundations of uncertainty quantification and the roles played in the more recent past by nuclear data uncertainties in nuclear data evaluations and nuclear applications. Significant advances that have established the mathematical framework for contemporary nuclear data evaluation methods, as well as the use of uncertainty information in nuclear data evaluation and nuclear applications, are described. This is followed by a brief examination of the current status concerning nuclear data evaluation methodology, covariance data generation, and the application of evaluated nuclear data uncertainties in contemporary nuclear technology. A few possible areas for future investigation of this subject are also suggested

Nuclear Data Uncertainty Quantification: Past, Present and Future

Science.gov (United States)

Smith, D. L.

2015-01-01

An historical overview is provided of the mathematical foundations of uncertainty quantification and the roles played in the more recent past by nuclear data uncertainties in nuclear data evaluations and nuclear applications. Significant advances that have established the mathematical framework for contemporary nuclear data evaluation methods, as well as the use of uncertainty information in nuclear data evaluation and nuclear applications, are described. This is followed by a brief examination of the current status concerning nuclear data evaluation methodology, covariance data generation, and the application of evaluated nuclear data uncertainties in contemporary nuclear technology. A few possible areas for future investigation of this subject are also suggested.

Current and future carbon budget at Takayama site, Japan, evaluated by a regional climate model and a process-based terrestrial ecosystem model.

Science.gov (United States)

Kuribayashi, Masatoshi; Noh, Nam-Jin; Saitoh, Taku M; Ito, Akihiko; Wakazuki, Yasutaka; Muraoka, Hiroyuki

2017-06-01

Accurate projection of carbon budget in forest ecosystems under future climate and atmospheric carbon dioxide (CO 2 ) concentration is important to evaluate the function of terrestrial ecosystems, which serve as a major sink of atmospheric CO 2 . In this study, we examined the effects of spatial resolution of meteorological data on the accuracies of ecosystem model simulation for canopy phenology and carbon budget such as gross primary production (GPP), ecosystem respiration (ER), and net ecosystem production (NEP) of a deciduous forest in Japan. Then, we simulated the future (around 2085) changes in canopy phenology and carbon budget of the forest by incorporating high-resolution meteorological data downscaled by a regional climate model. The ecosystem model overestimated GPP and ER when we inputted low-resolution data, which have warming biases over mountainous landscape. But, it reproduced canopy phenology and carbon budget well, when we inputted high-resolution data. Under the future climate, earlier leaf expansion and delayed leaf fall by about 10 days compared with the present state was simulated, and also, GPP, ER and NEP were estimated to increase by 25.2%, 23.7% and 35.4%, respectively. Sensitivity analysis showed that the increase of NEP in June and October would be mainly caused by rising temperature, whereas that in July and August would be largely attributable to CO 2 fertilization. This study suggests that the downscaling of future climate data enable us to project more reliable carbon budget of forest ecosystem in mountainous landscape than the low-resolution simulation due to the better predictions of leaf expansion and shedding.

The decisive future of inflation

Science.gov (United States)

Hardwick, Robert J.; Vennin, Vincent; Wands, David

2018-05-01

How much more will we learn about single-field inflationary models in the future? We address this question in the context of Bayesian design and information theory. We develop a novel method to compute the expected utility of deciding between models and apply it to a set of futuristic measurements. This necessarily requires one to evaluate the Bayesian evidence many thousands of times over, which is numerically challenging. We show how this can be done using a number of simplifying assumptions and discuss their validity. We also modify the form of the expected utility, as previously introduced in the literature in different contexts, in order to partition each possible future into either the rejection of models at the level of the maximum likelihood or the decision between models using Bayesian model comparison. We then quantify the ability of future experiments to constrain the reheating temperature and the scalar running. Our approach allows us to discuss possible strategies for maximising information from future cosmological surveys. In particular, our conclusions suggest that, in the context of inflationary model selection, a decrease in the measurement uncertainty of the scalar spectral index would be more decisive than a decrease in the uncertainty in the tensor-to-scalar ratio. We have incorporated our approach into a publicly available python class, foxi,1 that can be readily applied to any survey optimisation problem.

Social costs and benefits of nuclear futures

International Nuclear Information System (INIS)

Pearce, D.

1979-01-01

The conceptual framework for evaluating which energy path is chosen is one of trading-off costs and benefits in a world of technological, economic and social uncertainty. The translation of this conceptual framework into an analytical format with empirical relevance is dealt with. Some salient features of cost benefit analysis are discussed. Actual costs and benefits of nuclear futures are then considered. Subjects discussed are: routine and non-routine radiation, waste management, proliferation, and civil liberties. A 'regret' matrix is presented showing the cost to any future generation if a decision on nuclear power is made now. (U.K.)

Pressure ulcer research : current and future perspectives

NARCIS (Netherlands)

Bader, D.L.; Bouten, C.V.C.; Colin, D.; Oomens, C.W.J.

2005-01-01

This book provides an up-to-date scientific account of all aspects related to pressure ulcers and pressure ulcer research, as well as evidence-based knowledge of pressure ulcer aetiology. Further, it describes current and future tools for evaluating patients at risk. It comprises 20 chapters by

Evaluation of Shipbuilding CAD/CAM/CIM Systems - Phase II (Requirements for Future Systems)

National Research Council Canada - National Science Library

Horvath, John; Ross, Jonathan M

1997-01-01

.... The purpose of the analysis was two fold: 1. To describe the requirements of a competitive, future-oriented computer-aided design/computer-aided manufacturing/computer-integrated management (CAD/CAMYCIM...

Evaluating the Past, Present, and Future of Regenerative Medicine: A Global View.

Science.gov (United States)

Ronfard, Vincent; Vertès, Alain A; May, Michael H; Dupraz, Anne; van Dyke, Mark E; Bayon, Yves

2017-04-01

"Evaluating the Past and Present of Regenerative Medicine (RM)" was the first part of an Industry Symposium dedicated to the subject during the 2015 TERMIS World Congress in Boston. This working session presented a critical review of the current RM landscape in Europe and North America with possible projections for the future. Interestingly, the RM development cycle seems to obey the Gartner hype cycle, now at the enlightenment phase, after past exaggerated expectations and discouragements, as suggested by increasing numbers of clinical trials and recent market approvals of RM solutions in both Europe (Glybera and Holoclar ® from Chiesi Pharma and Strimvelis ® from GSK) and Japan (Remestemcel-L from Mesoblast ® ). The successful commercial translation of RM research is governed by five major drivers: (i) fully validated manufacturing capability for autologous or allogeneic products, (ii) reimbursement for targeted clinical indications with high and demonstrable medico-economic benefits versus standard of care, (iii) implication of regulatory bodies in the design and development plan of any RM solution, which should be well characterized, robust, with proven consistent efficacy and an acceptable and controlled positive benefit/risk ratio, (iv) collaborations facilitated by multicompetence hubs/consortia of excellence, (v) well-thought-out clinical development plans for reducing the risk of failure. Benefiting from past and present experience, the RM burgeoning industry is expected to accelerate the market release of cost-effective RM products with real curative potential for specific clinical indications with high unmet needs. This should be achieved by wisely leveraging all possible synergies of the different stakeholders, for example, patients, clinicians, reimbursement and health technology assessment (HTA) agencies, regulatory authorities, public/private investors, academia, and companies.

Evaluation of the electric utility missions; Evaluation des missions de service public de l'electricite

Energy Technology Data Exchange (ETDEWEB)

Syrota, J

2000-07-01

The French law from February 10, 2000, about the modernization and development of the electric utility, has created new missions of public utility and foresees some compensation mechanisms for not handicapping the power operators in charge of these missions and for not creating competition distortions to their detriment on the European market. The author explains, first, the financial and economical stakes linked with these new missions. Then, he evokes the evolution of the energy context that has taken place between the 2. World war and the enforcement of the February 10, 2000 law, and he analyzes the systems foreseen for the power generation and distribution. For each public utility charge, the existing dispositions and those introduced by the law are analyzed and compared to the equivalent systems existing in other countries. Then, charge evaluation criteria and sharing rules and proposed. (J.S.)

Creative Futures: Act, Sing, Play. Evaluation Report and Executive Summary

Science.gov (United States)

Haywood, Sarah; Griggs, Julia; Lloyd, Cheryl; Morris, Stephen; Kiss, Zsolt; Skipp, Amy

2015-01-01

Act, Sing, Play (ASP) offered music and drama tuition to Year 2 pupils. The aim of the programme was to evaluate whether music workshops had a bigger impact than drama workshops in terms of pupils' maths and literacy attainment. The evaluation was based on the hypothesis that participation in high-quality music instruction promotes educational…

Future orientation: a construct with implications for adolescent health and wellbeing.

Science.gov (United States)

Johnson, Sarah R Lindstrom; Blum, Robert W; Cheng, Tina L

2014-01-01

Multidisciplinary research has supported a relationship between adolescent future orientation (the ability to set future goals and plans) and positive adolescent health and development outcomes. Many preventive strategies - for example, contracepting, exercising - are based on taking actions in the present to avoid unwanted or negative future consequences. However, research has been hampered by unclear and often divergent conceptualizations of the future orientation construct. The present paper aims to integrate previous conceptual and operational definitions into a conceptual framework that can inform programs and services for youth and efforts to evaluate future orientation as a target for intervention. Recommendations focus on furthering the study of the construct through measurement synthesis as well as studies of the normative development of future orientation. Also suggested is the need to pair environmental intervention strategies with individual level efforts to improve future orientation in order to maximize benefits.

Detrimental effects of physical inactivity on neurogenesis

Directory of Open Access Journals (Sweden)

Trenton Lippert

2016-01-01

Full Text Available Patients diagnosed with neurological disorders exhibit a variety of physical and psychiatric symptoms, including muscle atrophy, general immobility, and depression. Patients who participate in physical rehabilitation at times show unexpected clinical improvement, which includes diminished depression and other stress-related behaviors. Regenerative medicine has advanced two major stem cell-based therapies for central nervous system (CNS disorders, transplantation of exogenous stem cells, and enhancing the endogenous neurogenesis. The latter therapy utilizes a natural method of re-innervating the injured brain, which may mend neurological impairments. In this study, we examine how inactivity-induced atrophy, using the hindlimb suspension model, alters neurogenesis in rats. The hypothesis is that inactivity inhibits neurogenesis by decreasing circulation growth or trophic factors, such as vascular endothelial growth or neurotrophic factors. The restriction modifies neurogenesis and stem cell differentiation in the CNS, the stem cell microenvironment is examined by the trophic and growth factors, including stress-related proteins. Despite growing evidence revealing the benefits of "increased" exercise on neurogenesis, the opposing theory involving "physical inactivity," which simulates pathological states, continues to be neglected. This novel theory will allow us to explore the effects on neurogenesis by an intransigent stem cell microenvironment likely generated by inactivity. 5-bromo-2-deoxyuridine labeling of proliferative cells, biochemical assays of serum, cerebrospinal fluid, and brain levels of trophic factors, growth factors, and stress-related proteins are suggested identifiers of neurogenesis, while evaluation of spontaneous movements will give insight into the psychomotor effects of inactivity. Investigations devised to show how in vivo stimulation, or lack thereof, affects the stem cell microenvironment are necessary to establish

Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival

International Nuclear Information System (INIS)

Paiva, Tadeu Ferreira Jr.; Jesus, Victor Hugo Fonseca de; Marques, Raul Amorim; Costa, Alexandre André Balieiro Anastácio da; Macedo, Mariana Petaccia de; Peresi, Patricia Maria; Damascena, Aline; Rossi, Benedito Mauro; Begnami, Maria Dirlei; Lima, Vladmir Cláudio Cordeiro de

2015-01-01

The development of targeted therapies has undoubtedly broadened therapeutic options for patients with colorectal cancer (CRC). The use of bevacizumab to reduce angiogenesis has been associated with improved clinical outcomes. However, an urgent need for prognostic/predictive biomarkers for anti-angiogenic therapies still exists. Clinical data of 105 CRC patients treated with bevacizumab in conjunction with chemotherapy were analyzed. The expression of vascular endothelial growth factor (VEGF) receptors, NOTCH1 receptor and its ligand DLL4 were determined by immunohistochemistry. Tumor samples were arranged on a tissue microarray. The association between protein expression and clinicopathological characteristics and outcomes was determined. Bevacizumab was administered as a first-line of treatment in 70.5 % of our cases. The median progression-free survival (PFS) was 10.2 months. The median overall survival (OS) of the total cohort was 24.4 months. Bevacizumab, as the first-line of treatment, and the presence of liver metastasis were independently associated with objective response rate. Membrane VEGFR1 and VEGFR3 expressions were associated with the presence of lung metastasis; interestingly, VEGFR3 was associated with less liver metastasis. NOTCH1 expression was associated with lymph node metastasis. There was a trend toward association between improved PFS and lower NOTCH1 expression (p = 0.06). Improved OS was significantly associated with lower NOTCH1 expression (p = 0.01). In a multivariate analysis, ECOG (Eastern Cooperative Oncology Group) performance status, liver metastasis, histological grade, and NOTCH1 expression were independently associated with OS. Our findings illustrated the expression profile of angiogenesis-related proteins and their association with clinicopathological characteristics and outcomes. NOTCH1 expression is a detrimental prognostic factor in metastatic CRC patients treated with chemotherapy plus bevacizumab. The online version of

Critical research needs for identifying future changes in Gulf coral reef ecosystems

KAUST Repository

Feary, David A.

2013-07-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/Persian Gulf (thereafter \\'Gulf\\') coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. © 2013 Elsevier Ltd.

Critical research needs for identifying future changes in Gulf coral reef ecosystems

Science.gov (United States)

Feary, David A.; Burt, John A.; Bauman, Andrew G.; Al Hazeem, Shaker; Abdel-Moati, Mohamed A.; Al-Khalifa, Khalifa A.; Anderson, Donald M.; Amos, Carl; Baker, Andrew; Bartholomew, Aaron; Bento, Rita; Cavalcante, Geórgenes H.; Chen, Chaolun Allen; Coles, Steve L.; Dab, Koosha; Fowler, Ashley M.; George, David; Grandcourt, Edwin; Hill, Ross; John, David M.; Jones, David A.; Keshavmurthy, Shashank; Mahmoud, Huda; Moradi Och Tapeh, Mahdi; Mostafavi, Pargol Ghavam; Naser, Humood; Pichon, Michel; Purkis, Sam; Riegl, Bernhard; Samimi-Namin, Kaveh; Sheppard, Charles; Vajed Samiei, Jahangir; Voolstra, Christian R.; Wiedenmann, Joerg

2014-01-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/ Persian Gulf (thereafter ‘Gulf’) coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. PMID:23643407

Critical research needs for identifying future changes in Gulf coral reef ecosystems

KAUST Repository

Feary, David A.; Burt, John A.; Bauman, Andrew G.; Al Hazeem, Shaker; Abdel-Moati, Mohamed A R; Al-Khalifa, Khalifa A.; Anderson, Donald M.; Amos, Carl L.; Baker, Andrew C.; Bartholomew, Aaron; Bento, Rita; Cavalcante, Geó rgenes H.; Chen, Chaolun Allen; Coles, Steve L.; Dab, Koosha; Fowler, Ashley M.; George, David Glen; Grandcourt, Edwin Mark; Hill, Ross; John, David Michael; Jones, David Alan; Keshavmurthy, Shashank; Mahmoud, Huda M A; Moradi Och Tapeh, Mahdi; Mostafavi, Pargol Ghavam; Naser, Humood A.; Pichon, Michel; Purkis, Sam J.; Riegl, Bernhard M.; Samimi-Namin, Kaveh; Sheppard, Charles R C; Vajed Samiei, Jahangir; Voolstra, Christian R.; Wiedenmann, Jö rg

2013-01-01

Expert opinion was assessed to identify current knowledge gaps in determining future changes in Arabian/Persian Gulf (thereafter 'Gulf') coral reefs. Thirty-one participants submitted 71 research questions that were peer-assessed in terms of scientific importance (i.e., filled a knowledge gap and was a research priority) and efficiency in resource use (i.e., was highly feasible and ecologically broad). Ten research questions, in six major research areas, were highly important for both understanding Gulf coral reef ecosystems and also an efficient use of limited research resources. These questions mirrored global evaluations of the importance of understanding and evaluating biodiversity, determining the potential impacts of climate change, the role of anthropogenic impacts in structuring coral reef communities, and economically evaluating coral reef communities. These questions provide guidance for future research on coral reef ecosystems within the Gulf, and enhance the potential for assessment and management of future changes in this globally significant region. © 2013 Elsevier Ltd.

Evaluation of replacement thread lubricants for red lead and graphite in mineral oil

Energy Technology Data Exchange (ETDEWEB)

Jungling, T.L.; Rauth, D.R.; Goldberg, D.

1998-04-30

Eight commercially available thread lubricants were evaluated to determine the best replacement for Red Lead and Graphite in Mineral Oil (RLGMO). The evaluation included coefficient of friction testing, high temperature anti-seizing testing, room temperature anti-galling testing, chemical analysis for detrimental impurities, corrosion testing, off-gas testing, and a review of health and environmental factors. The coefficient of friction testing covered a wide variety of factors including stud, nut, and washer materials, sizes, manufacturing methods, surface coatings, surface finishes, applied loads, run-in cycles, and relubrication. Only one lubricant, Dow Corning Molykote P37, met all the criteria established for a replacement lubricant. It has a coefficient of friction range similar to RLGMO. Therefore, it can be substituted directly for RLGMO without changing the currently specified fastener torque values for the sizes, materials and conditions evaluated. Other lubricants did not perform as well as Molykote P37 in one or more test or evaluation categories.

Exercise as a mean to reverse the detrimental effect of high-fat diet on bone’s fracture characteristics

Directory of Open Access Journals (Sweden)

Ilias Doulamis

2017-04-01

Full Text Available The aim of this study is to investigate whether exercise can reverse some of the adverse effects of high-fat-diet-induced obesity on lipid metabolism and bone biomechanical properties. A total of 26 adult male C57bl/6J mice were randomly assigned into three groups: (A Control group (n=6, (B High-fat diet group (n=10, (C High-fat diet and exercise group (n=10. Body mass and relevant biochemical parameters were measured for the duration of the experimental protocol (37 weeks. Mechanical strength of both femurs of each animal was assessed in-vitro based on three point bending tests. It was re¬vealed that exposure to high-fat diet led to significant increase of body mass and cholesterol levels and also to substantial changes in bone mor-phology and strength. Ultimate stress for the animals exposed to high-fat diet and those exposed to high-fat-diet and exercise was 25% and 24% lower compared to control, respectively. Exercise increased bone thickness by 15% compared to animals that were not exposed to exer¬cise. It was concluded that high-fat-diet ap¬pears to have a detrimental effect on bone biomechanics and strength. Exer¬cise reversed the reduction in bone thickness that appears to be induced by high-fat diet. However no statistically significant increase in bone strength was observed.

Ports and pests: Assessing the threat of aquatic invasive species introduced by maritime shipping activity in Cuba.

Science.gov (United States)

O'Brien, Charleen E; Johnston, Matthew W; Kerstetter, David W

2017-12-15

Aquatic invasive species (AIS) are biological pollutants that cause detrimental ecological, economic, and human-health effects in their introduced communities. With increasing globalization through maritime trade, ports are vulnerable to AIS exposure via commercial vessels. The Cuban Port of Mariel is poised to become a competitive transshipment hub in the Caribbean and the intent of this study was to evaluate present and potential impacts AIS pose with the likely future increase in shipping activity. We utilized previous assessment frameworks and publicly accessible information to rank AIS by level of threat. Fifteen AIS were identified in Cuba and one, the Asian green mussel Perna viridis (Linnaeus, 1758), had repeated harmful economic impacts. Five species associated with trade partners of Port Mariel were considered potentially detrimental to Cuba if introduced through shipping routes. The results presented herein identify species of concern and emphasize the importance of prioritizing AIS prevention and management within Cuba. Copyright © 2017 Elsevier Ltd. All rights reserved.

Medical beam monitor—Pre-clinical evaluation and future applications

Science.gov (United States)

Frais-Kölbl, Helmut; Griesmayer, Erich; Schreiner, Thomas; Georg, Dietmar; Pernegger, Heinz

2007-10-01

Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

Medical beam monitor—Pre-clinical evaluation and future applications

CERN Document Server

Frais-Kölbl, H; Schreiner, T; Georg, D; Pernegger, H

2007-01-01

Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

Energy futures

International Nuclear Information System (INIS)

Treat, J.E.

1990-01-01

This book provides fifteen of the futures industry's leading authorities with broader background in both theory and practice of energy futures trading in this updated text. The authors review the history of the futures market and the fundamentals of trading, hedging, and technical analysis; then they update you with the newest trends in energy futures trading - natural gas futures, options, regulations, and new information services. The appendices outline examples of possible contracts and their construction

Portfolio Diversification with Commodity Futures: Properties of Levered Futures

NARCIS (Netherlands)

Woodard, J.D.; Egelkraut, T.M.; Garcia, P.; Pennings, J.M.E.

2005-01-01

Portfolio Diversification with Commodity Futures: Properties of Levered Futures This study extends previous work on the impact of commodity futures on portfolio performance by explicitly incorporating levered futures into the portfolio optimization problem. Using data on nine individual commodity

Analysis and evaluation of the moral distress theory.

Science.gov (United States)

Wilson, Melissa A

2018-04-01

Moral distress is a pervasive problem in nursing resulting in a detriment to patient care, providers, and organizations. Over a decade ago, the moral distress theory (MDT) was proposed and utilized in multiple research studies. This middle range theory explains and predicts the distress that occurs in a nurse because of moral conflict. The research findings born from this theory have been substantial. Since inception of this theory, moral distress has been extensively examined which has further elaborated its understanding. This paper provides an analysis and evaluation of the MDT according to applicable guidelines. Current understanding of the phenomenon indicates that a new theory may be warranted to better predict, treat, and manage moral distress. © 2017 Wiley Periodicals, Inc.

Tracers and contrast agents in cardiovascular imaging: present and future

International Nuclear Information System (INIS)

Marmion, M.; Deutsch, E.

1996-01-01

This brief article addresses the current status and future potential of nuclear medicine, X-ray computed tomography (CT), ultrasound (US), and magnetic resonance (MR) imaging in the diagnosis of cardiovascular diseases. The currently perceived advantages and disadvantages, as well as the possible future roles, of each of the modalities with regard to the evaluation of coronary artery disease are delineated. The certain advent of Mr and US myocardial contrast agents, combined with the inexorable pressures of health care reform, will alter the future usage patterns of all four modalities. Future debates about which modality should be used in which clinical situation will be based not on 'anatomy vs function', nor on the issues of cost effectiveness and patient outcomes

Automatic Evaluations and Exercising: Systematic Review and Implications for Future Research.

Science.gov (United States)

Schinkoeth, Michaela; Antoniewicz, Franziska

2017-01-01

The general purpose of this systematic review was to summarize, structure and evaluate the findings on automatic evaluations of exercising. Studies were eligible for inclusion if they reported measuring automatic evaluations of exercising with an implicit measure and assessed some kind of exercise variable. Fourteen nonexperimental and six experimental studies (out of a total N = 1,928) were identified and rated by two independent reviewers. The main study characteristics were extracted and the grade of evidence for each study evaluated. First, results revealed a large heterogeneity in the applied measures to assess automatic evaluations of exercising and the exercise variables. Generally, small to large-sized significant relations between automatic evaluations of exercising and exercise variables were identified in the vast majority of studies. The review offers a systematization of the various examined exercise variables and prompts to differentiate more carefully between actually observed exercise behavior (proximal exercise indicator) and associated physiological or psychological variables (distal exercise indicator). Second, a lack of transparent reported reflections on the differing theoretical basis leading to the use of specific implicit measures was observed. Implicit measures should be applied purposefully, taking into consideration the individual advantages or disadvantages of the measures. Third, 12 studies were rated as providing first-grade evidence (lowest grade of evidence), five represent second-grade and three were rated as third-grade evidence. There is a dramatic lack of experimental studies, which are essential for illustrating the cause-effect relation between automatic evaluations of exercising and exercise and investigating under which conditions automatic evaluations of exercising influence behavior. Conclusions about the necessity of exercise interventions targeted at the alteration of automatic evaluations of exercising should therefore

A memory advantage for past-oriented over future-oriented performance feedback.

Science.gov (United States)

Nash, Robert A; Winstone, Naomi E; Gregory, Samantha E A; Papps, Emily

2018-03-05

People frequently receive performance feedback that describes how well they achieved in the past, and how they could improve in future. In educational contexts, future-oriented (directive) feedback is often argued to be more valuable to learners than past-oriented (evaluative) feedback; critically, prior research led us to predict that it should also be better remembered. We tested this prediction in six experiments. Subjects read written feedback containing evaluative and directive comments, which supposedly related to essays they had previously written (Experiments 1-2), or to essays another person had written (Experiments 3-6). Subjects then tried to reproduce the feedback from memory after a short delay. In all six experiments, the data strongly revealed the opposite effect to the one we predicted: despite only small differences in wording, evaluative feedback was in fact recalled consistently better than directive feedback. Furthermore, even when adult subjects did recall directive feedback, they frequently misremembered it in an evaluative style. These findings appear at odds with the position that being oriented toward the future is advantageous to memory. They also raise important questions about the possible behavioral effects and generalizability of such biases, in terms of students' academic performance. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Future thinking instructions improve prospective memory performance in adolescents.

Science.gov (United States)

Altgassen, Mareike; Kretschmer, Anett; Schnitzspahn, Katharina Marlene

2017-07-01

Studies on prospective memory (PM) development in adolescents point to age-related increases through to adulthood. The goal of the present study was to examine whether instructing adolescents to engage in an episodic prospection of themselves executing future actions (i.e., future thinking) when forming an intention would improve their PM performance and reduce age-related differences. Further, we set out to explore whether future thinking instructions result in stronger memory traces and/or stronger cue-context associations by evaluating retrospective memory for the PM cues after task completion and monitoring costs during PM task processing. Adolescents and young adults were allocated to either the future thinking, repeated-encoding or standard condition. As expected, adolescents had fewer correct PM responses than young adults. Across age groups, PM performance in the standard condition was lower than in the other encoding conditions. Importantly, the results indicate a significant interaction of age by encoding condition. While adolescents benefited most from future thinking instructions, young adults performed best in the repeated-encoding condition. The results also indicate that the beneficial effects of future thinking may result from deeper intention-encoding through the simulation of future task performance.

Evaluation of the electric utility missions

International Nuclear Information System (INIS)

Syrota, J.

2000-01-01

The French law from February 10, 2000, about the modernization and development of the electric utility, has created new missions of public utility and foresees some compensation mechanisms for not handicapping the power operators in charge of these missions and for not creating competition distortions to their detriment on the European market. The author explains, first, the financial and economical stakes linked with these new missions. Then, he evokes the evolution of the energy context that has taken place between the 2. World war and the enforcement of the February 10, 2000 law, and he analyzes the systems foreseen for the power generation and distribution. For each public utility charge, the existing dispositions and those introduced by the law are analyzed and compared to the equivalent systems existing in other countries. Then, charge evaluation criteria and sharing rules and proposed. (J.S.)

Estimate of radiation detriment long period after exposure to low doses of ionizing radiation: Chromosomal aberrations in liquidators 6-10 years after the Chernobyl accident

International Nuclear Information System (INIS)

Nikiforov, A.M.; Slozina, N.M.; Neronova, E.G.; Kharchenko, T.V.; Drygina, L.B.; Strukov, E.L.

1997-01-01

The group of 297 liquidators was cytogenetically investigated 6 - 10 years after the Chernobyl accident. The significantly increased level of chromosomal and chromatid types exchange aberrations was shown. For all subjects questionnaires that provide consideration of known and suspected confounding variables were filled in. The participation in recovery works at the Chernobyl nuclear power station was the only reason for dicentrics and rings rise in liquidators. An investigation of the tumor-specific markers (CEA, AFP, CA19-9, PSA, NSE) was carried out in 56 liquidators simultaneously with chromosomal analysis. The increased level of NSE was found in liquidators bearing the chromosomal aberrations of exchange type. The results of this work let us to consider the liquidators who underwent to low doses of ionizing radiation 6-10 years ago as a detrimental group that needs special scientific and medical attention. (author)

A safety re-evaluation of the AVR pebble bed reactor operation and its consequences for future HTR concepts

Energy Technology Data Exchange (ETDEWEB)

Moormann, R.

2008-06-15

The AVR pebble bed reactor (46 MW{sub th}) was operated 1967-88 at coolant outlet temperatures up to 990 C. A principle difference of pebble bed HTRs as AVR to conventional reactors is the continuous movement of fuel element pebbles through the core which complicates thermohydraulic, nuclear and safety estimations. Also because of a lack of other experience AVR operation is still a relevant basis for future pebble bed HTRs and thus requires careful examination. This paper deals mainly with some insufficiently published unresolved safety problems of AVR operation and of pebble bed HTRs but skips the widely known advantageous features of pebble bed HTRs. The AVR primary circuit is heavily contaminated with metallic fission products (Sr-90, Cs-137) which create problems in current dismantling. The amount of this contamination is not exactly known, but the evaluation of fission product deposition experiments indicates that the end of life contamination reached several percent of a single core inventory, which is some orders of magnitude more than precalculated and far more than in large LWRs. A major fraction of this contamination is bound on graphitic dust and thus partly mobile in depressurization accidents, which has to be considered in safety analyses of future reactors. A re-evaluation of the AVR contamination is performed here in order to quantify consequences for future HTRs (400 MW{sub th}). It leads to the conclusion that the AVR contamination was mainly caused by inadmissible high core temperatures, increasing fission product release rates, and not - as presumed in the past - by inadequate fuel quality only. The high AVR core temperatures were detected not earlier than one year before final AVR shut-down, because a pebble bed core cannot yet be equipped with instruments. The maximum core temperatures are still unknown but were more than 200 K higher than calculated. Further, azimuthal temperature differences at the active core margin of up to 200 K were

A safety re-evaluation of the AVR pebble bed reactor operation and its consequences for future HTR concepts

International Nuclear Information System (INIS)

Moormann, R.

2008-06-01

The AVR pebble bed reactor (46 MW th ) was operated 1967-88 at coolant outlet temperatures up to 990 C. A principle difference of pebble bed HTRs as AVR to conventional reactors is the continuous movement of fuel element pebbles through the core which complicates thermohydraulic, nuclear and safety estimations. Also because of a lack of other experience AVR operation is still a relevant basis for future pebble bed HTRs and thus requires careful examination. This paper deals mainly with some insufficiently published unresolved safety problems of AVR operation and of pebble bed HTRs but skips the widely known advantageous features of pebble bed HTRs. The AVR primary circuit is heavily contaminated with metallic fission products (Sr-90, Cs-137) which create problems in current dismantling. The amount of this contamination is not exactly known, but the evaluation of fission product deposition experiments indicates that the end of life contamination reached several percent of a single core inventory, which is some orders of magnitude more than precalculated and far more than in large LWRs. A major fraction of this contamination is bound on graphitic dust and thus partly mobile in depressurization accidents, which has to be considered in safety analyses of future reactors. A re-evaluation of the AVR contamination is performed here in order to quantify consequences for future HTRs (400 MW th ). It leads to the conclusion that the AVR contamination was mainly caused by inadmissible high core temperatures, increasing fission product release rates, and not - as presumed in the past - by inadequate fuel quality only. The high AVR core temperatures were detected not earlier than one year before final AVR shut-down, because a pebble bed core cannot yet be equipped with instruments. The maximum core temperatures are still unknown but were more than 200 K higher than calculated. Further, azimuthal temperature differences at the active core margin of up to 200 K were observed

Estrogen receptor-α mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract

International Nuclear Information System (INIS)

Couse, John F.; Korach, Kenneth S.

2004-01-01

It is generally believed that estrogen receptor-dependent and -independent pathways are involved in mediating the developmental effects of the synthetic estrogen, diethylstilbestrol (DES). However, the precise role and extent to which each pathway contributes to the resulting pathologies remains unknown. We have employed the estrogen receptor knockout (ERKO) mice, which lack either estrogen receptor-α (αERKO or estrogen receptor-β (βERKO), to gain insight into the contribution of each ER-dependent pathway in mediating the effects of neonatal DES exposure in the female and male reproductive tract tissues of the mouse. Estrogen receptor-α female mice exhibited complete resistance to the chronic effects of neonatal DES exposure that were obvious in exposed wild-type animals, including atrophy and epithelial squamous metaplasia in the uterus; proliferative lesions of the oviduct; and persistent cornification of the vaginal epithelium. DES-mediated reduction in uterine Hoxa10, Hoxa11 and Wnt7a expression that occurs wild-type females during the time of exposure was also absent in αERKO females. In the male, αERKO mice exhibited complete resistance to the chronic effects of neonatal DES exposure on the prostate, including decreased androgen receptor levels, epithelial hyperplasia, and increased basal cell proliferation. Although ERβ is highly expressed in the prostate epithelium, DES-exposed βERKO males exhibited all of the effects of neonatal DES exposure that were observed in similarly exposed wild-type males. Therefore, the lack of DES-effects on gene expression and tissue differentiation in the αERKO uterus and prostate provides unequivocal evidence of an obligatory role for ERα in mediating the detrimental actions of neonatal DES exposure in the murine reproductive tract

Modeling and forecasting petroleum futures volatility

International Nuclear Information System (INIS)

Sadorsky, Perry

2006-01-01

Forecasts of oil price volatility are important inputs into macroeconometric models, financial market risk assessment calculations like value at risk, and option pricing formulas for futures contracts. This paper uses several different univariate and multivariate statistical models to estimate forecasts of daily volatility in petroleum futures price returns. The out-of-sample forecasts are evaluated using forecast accuracy tests and market timing tests. The TGARCH model fits well for heating oil and natural gas volatility and the GARCH model fits well for crude oil and unleaded gasoline volatility. Simple moving average models seem to fit well in some cases provided the correct order is chosen. Despite the increased complexity, models like state space, vector autoregression and bivariate GARCH do not perform as well as the single equation GARCH model. Most models out perform a random walk and there is evidence of market timing. Parametric and non-parametric value at risk measures are calculated and compared. Non-parametric models outperform the parametric models in terms of number of exceedences in backtests. These results are useful for anyone needing forecasts of petroleum futures volatility. (author)

Problem and future of radiation hazard in IVR

International Nuclear Information System (INIS)

Chida, Koichi; Maruoka, Shin; Saito, Haruo; Ishibashi, Tadashi; Takai, Yoshihiro

2008-01-01

This paper describes problems of radiation exposure to patients and operators, their dose assessment and future in the radio-protection at IVR (interventional radiology) like percutaneous coronary intervention. Patients who undergo the IVR operation are usually faced to dying risk and thereby the actually still occurring radiation injury is often justified. However, effort must be taken based on measurement and dose assessment of the radiation to reduce the exposure dose in patients, which, authors comment, leads to the decrease of dose also to the operators derived mainly from scattering. Presently in IVR, however, there are scarce methods to directly measure and assess the maximal exposure dose of patient's skin in a real time, and therefore which are tasks remained in future. Practically used is the evaluation of the overall dose by parameters like exposing hours and area dose values (International Commission of Radiological Protection (ICRP), 2001 and Food and Drug Administration (FDA), 1995), and/or by IVR-reference point method (International Electrotechnical Commission, 2000). The latter is on the defined point 15-cm distant from the isocenter toward X-ray tube focus and the concept is already incorporated in Japan Industrial Standard. Those evaluations are conceivably helpful for future assessment of IVR radiation effects involving carcinogenesis. (R.T.)

Anticipated future of Latvia and Russia during a global economic crisis: A mixed methods perspective

Directory of Open Access Journals (Sweden)

Kolesovs Aleksandrs

2014-01-01

Full Text Available This cross-cultural study explored subjective predictors of more positive evaluation of the future of the country during a global socioeconomic crisis. A sequential mixed-method design was chosen for an exploration of students’ expectations in Russia and Latvia as countries contrasting in macro-contextual conditions. In 2009, Study 1 was designed as a thematic analysis of essays on topic “The Future of Latvia/Russia”. The results demonstrated that the future of a country is anticipated by taking into account external influences, the present of the country, and its perceived power and stability. In 2011, Study 2 involved these themes as independent variables in a multiple regression model. The results demonstrated that positive evaluation of the present and higher perceived power of the country are individuallevel predictors of more positive evaluation of its future. Observed concordance of models indicates relatively high importance of subjective view of the country in the changing world.

ANDERS: future of concrete bridge deck evaluation and rehabilitation

Science.gov (United States)

Gucunski, Nenad; Moon, Franklin

2011-04-01

The Automated Nondestructive Evaluation and Rehabilitation System (ANDERS) aims to provide a uniquely comprehensive tool that will transform the manner in which bridge decks are assessed and rehabilitated. It is going to be achieved through: 1) much higher evaluation detail and comprehensiveness of detection at an early stage deterioration, 2) comprehensive condition and structural assessment at all stages of deterioration, and 3) integrated assessment and rehabilitation that will be minimally invasive, rapid and cost effective. ANDERS is composed of four systems. that merge novel imaging and NDE techniques, together with novel intervention approaches to arrest the deterioration processes. These technologies are incorporated within a series of human-operated and robotic vehicles. To perform assessments, ANDERS will be equipped with two complimentary nondestructive approaches. The first, Multi-Modal Nondestructive Evaluation (MM-NDE) System aims to identify and characterize localized deterioration with a high degree of resolution. The second, Global Structural Assessment (GSA) System aims to capture global structural characteristics and identify any appreciable effects of deterioration on a bridge structure. Output from these two approaches will be merged through a novel Automated Structural Identification (Auto St-Id) approach that will construct, calibrate, and utilize simulation models to assess overall structural vulnerability and capacity. These three systems comprise the assessment suite of ANDERS and will directly inform the Nondestructive Rehabilitation (NDR) System. The NDR System leverages robotics for the precision and rapid delivery of novel materials capable of halting the early-stage deterioration identified.

Fit between Future Thinking and Future Orientation on Creative Imagination

Science.gov (United States)

Chiu, Fa-Chung

2012-01-01

The purpose of the current study is to investigate the impact of future thinking, and the fit between future thinking and future orientation on creative thinking. In Study 1, 83 undergraduates were randomly assigned to three groups: 50-year future thinking, 5-year future thinking, and the present-day thinking. First, the priming tasks, in which…

A proposed approach for enhancing design safety assurance of future plants

International Nuclear Information System (INIS)

Oh, Kyu Myeng; Ahn, Sang Kyu; Lee, Chang Ju; Kim, Inn Seock

2010-01-01

This paper provides various insights from a detailed review of deterministic approaches typically applied to ensure design safety of nuclear power plants (NPPs) and risk-informed approaches proposed to evaluate safety of advanced reactors such as Generation IV reactors. Also considered herein are the risk-informed safety analysis (RISA) methodology suggested by Westinghouse as a means to improve the conventional accident analysis, together with the Technology Neutral Framework recently suggested by the U.S. NRC for safety evaluation of future plants. These insights from the comparative review of deterministic and risk-informed approaches could be used in further enhancing the methodology for design safety assurance of future plants

Turning the big knob: an evaluation of the use of energy policy to modulate future climate impacts

International Nuclear Information System (INIS)

Pielke, R.A. Jnr.; Klein, R.; Sarewitz, D.

2000-01-01

Conventional wisdom on climate change policy is straightforward: reducing greenhouse gas emissions will avoid the increased frequency and magnitude of climate impacts on environment and society that might occur if emissions are not controlled. The proponents of conventional wisdom widely consider energy policy to be the main policy tool available to decision makers to intentionally modulate future climate impacts. In this paper we challenge the notion that policy makers should intentionally use energy policy to modulate future climate impacts. The paper argues that policy makers may well make large changes in energy policy (and future emissions) without significantly affecting future climate impacts. In other words, even if a theoretical case could be made that energy policy could be used intentionally to modulate future climate, other factors will play a larger role in creating future impact.y and are arguably more amenable to policy change. To illustrate this conclusion, the paper presents a sensitivity analysis under the assumptions of the Intergovernmental Panel on Climate Change for the case of tropical cyclones. One implication of the paper's conclusions is that policy responses to extreme weather events should be decoupled from considerations of energy policy. This decoupling is not intended to diminish either the importance of responding to climate change or of energy policy. Rather, it is to emphasise that there are many responses under the rubric of adaptation that could play a much greater role in reducing societal vulnerability to losses. One of the implications of this change is that scientific uncertainty need not stand in the way of effective action because the measures proposed make sense under any future climate scenario. (author)

THEORETICAL ANALYSIS STUDY OF FORMATION OF FUTURE LEGAL LAWYERS

Directory of Open Access Journals (Sweden)

Eugene Stepanovich Shevlakov

2015-09-01

Full Text Available The article deals with topical issues of formation of legal consciousness of future lawyers in high school. Obtained kinds of legal consciousness of future lawyers, determined its structure. Dedicated components of justice are mutually reinforcing, and provide an opportunity for further development of the personality of the future specialist, their personal growth.The purpose: to carry out theoretical analysis of the problem of formation of legal consciousness of future lawyers.The novelty is based. On the analysis of theoretical appro-aches of pedagogy, psychology, law, the notion of «lawfulness of the future of the law student», which is regarded as a form of social consciousness, which is a set of legal views and feelings, expressing the attitude to the law and legal phenomena that have regulatory in character and which includes know-ledge of legal phenomena and their evaluation from the point of view of fairness and justice, formed in the process of studying in the University.Results: this article analyzes different approaches to understanding the content and essence of the concept of legal consciousness of the legal profession. Define the types and structure of legal consciousness of future lawyers.

Medical Students' Perspective Towards Their Future Medical Practice

African Journals Online (AJOL)

Objectives:To evaluate the influencing factors towards choice of the medical profession and attitude towards future medical practice. Subjects and methods: One hundred thirty four students of the Gondar College of Medical Sciences were included in the study. Data was collected by using self-administered questionnaires.

Procrastination, consideration of future consequences, and episodic future thinking.

Science.gov (United States)

Rebetez, Marie My Lien; Barsics, Catherine; Rochat, Lucien; D'Argembeau, Arnaud; Van der Linden, Martial

2016-05-01

Despite the intrinsic temporal nature of procrastination, little research has examined the link between this form of self-regulatory failure and the consideration of future consequences, and no study has addressed the link between procrastination and episodic future thinking. The aim of the present study was to explore these relationships. Participants were asked to project themselves into possible future events and to rate the amount of sensory-perceptual details and autonoetic consciousness associated with their representations. They were also asked to complete questionnaires that assessed procrastination, the consideration of future consequences, and negative affect. Results showed that both the consideration of future consequences and episodic future thinking were associated with procrastination, and in particular with procrastination-related decision making abilities and procrastination-related motivational dispositions, respectively. Copyright © 2016 Elsevier Inc. All rights reserved.

Future metrology needs for FEL reflective optics

International Nuclear Information System (INIS)

Assoufid, L.

2000-01-01

An International Workshop on Metrology for X-ray and Neutron Optics has been held March 16-17, 2000, at the Advanced Photon Source, Argonne National Laboratory, near Chicago, Illinois (USA). The workshop gathered engineers and scientists from both the U.S. and around the world to evaluate metrology instrumentation and methods used to characterize surface figure and finish for long grazing incidence optics used in beamlines at synchrotrons radiation sources. This two-day workshop was motivated by the rapid evolution in the performance of x-ray and neutron sources along with requirements in optics figure and finish. More specifically, the performance of future light sources, such as free-electron laser (FEL)-based x-ray sources, is being pushed to new limits in term of both brilliance and coherence. As a consequence, tolerances on surface figure and finish of the next generation of optics are expected to become tighter. The timing of the workshop provided an excellent opportunity to study the problem, evaluate the state of the art in metrology instrumentation, and stimulate innovation on future metrology instruments and techniques to be used to characterize these optics. This paper focuses on FEL optics and metrology needs. (A more comprehensive summary of the workshop can be found elsewhere.) The performance and limitations of current metrology instrumentation will be discussed and recommendations from the workshop on future metrology development to meet the FEL challenges will be detailed

Future metrology needs for FEL reflective optics.

Energy Technology Data Exchange (ETDEWEB)

Assoufid, L.

2000-09-21

An International Workshop on Metrology for X-ray and Neutron Optics has been held March 16-17, 2000, at the Advanced Photon Source, Argonne National Laboratory, near Chicago, Illinois (USA). The workshop gathered engineers and scientists from both the U.S. and around the world to evaluate metrology instrumentation and methods used to characterize surface figure and finish for long grazing incidence optics used in beamlines at synchrotrons radiation sources. This two-day workshop was motivated by the rapid evolution in the performance of x-ray and neutron sources along with requirements in optics figure and finish. More specifically, the performance of future light sources, such as free-electron laser (FEL)-based x-ray sources, is being pushed to new limits in term of both brilliance and coherence. As a consequence, tolerances on surface figure and finish of the next generation of optics are expected to become tighter. The timing of the workshop provided an excellent opportunity to study the problem, evaluate the state of the art in metrology instrumentation, and stimulate innovation on future metrology instruments and techniques to be used to characterize these optics. This paper focuses on FEL optics and metrology needs. (A more comprehensive summary of the workshop can be found elsewhere.) The performance and limitations of current metrology instrumentation will be discussed and recommendations from the workshop on future metrology development to meet the FEL challenges will be detailed.

Flavour tagging at the future linear collider

International Nuclear Information System (INIS)

Hansen, S.X.

2003-01-01

High performance flavour tagging of jets containing heavy flavours is crucial for the studies planned for the future high energy e + e - Linear Collider (LC). Pixel detectors have proven to provide very powerful flavour identification, for this reason the Linear Collider Flavour Identification collaboration has decided to concentrate its R and D work for the future LC on a Charged Coupled Device pixel vertex detector, and study the flavour tagging performance of the design to optimize it. In this work we first evaluate the basic tracking performance. We then estimate the flavour tagging performance of the present detector layout, using a neural network approach. We conclude by studying the energy dependence of the performance

Future nuclear energy scenarios for Europe

International Nuclear Information System (INIS)

Roelofs, F.; Van Heek, A.

2010-01-01

Nuclear energy is back on the agenda worldwide. In order to prepare for the next decades and to set priorities in nuclear R and D and investment, market share scenarios are evaluated. This allows to identify the triggers which influence the market penetration of future nuclear reactor technologies. To this purpose, scenarios for a future nuclear reactor park in Europe have been analysed applying an integrated dynamic process modelling technique. Various market share scenarios for nuclear energy are derived including sub-variants with regard to the intra-nuclear options taken, e.g. introduction date of Gen-III (i.e. EPR) and Gen-IV (i.e. SCWR, HTR, FR) reactors, level of reprocessing, and so forth. The assessment was undertaken using the DANESS code which allows to provide a complete picture of mass-flow and economics of the various nuclear energy system scenarios. The analyses show that the future European nuclear park will exist of combinations of Gen-III and Gen-IV reactors. This mix will always consist of a set of reactor types each having its specific strengths. Furthermore, the analyses highlight the triggers influencing the choice between different nuclear energy deployment scenarios. In addition, a dynamic assessment is made with regard to manpower requirements for the construction of a future nuclear fleet in the different scenarios. (authors)

Present and future of flat panel detectors in the world

International Nuclear Information System (INIS)

Inamura, Kiyonari

2002-01-01

Present status of development of flat panel detectors and their clinical application in the world have been surveyed, and future trends are also explored especially in the field of material researches and methods of manufacturing. Also the importance of role of medical physicists on user side is described because characteristic physics measurement of a detector assembly is unavoidable and essential in quality assurance in clinical routine and acceptance test in hospitals. Even though physics measurements and clinical evaluations on flat panel detectors have shown remarkable progress and advances in these several years, future problems of cost down in manufacturing and quality assurance to prevent individual differences between detector assemblies must be resolved. Results of evaluation in mammography, chest radiography, fluoroscopy for cardiovascular examination, bone tumor examination and radiotherapy application indicate that flat panel detectors are future promising materials. Their systematic operation is contributing to heighten accuracy of image examinations and preciseness of radiation therapy. Encouragement to medical physicists relevant to flat panel detectors is also raised in this paper. (author)

Future spent nuclear fuel and radioactive waste infrastructure in Norway

International Nuclear Information System (INIS)

Soerlie, A.A.

2002-01-01

In Norway a Governmental Committee was appointed in 1991 to make an evaluation of the future steps that need to be taken in Norway to find a final solution for the spent nuclear fuel and for some other radioactive waste for which a disposal option does not exist today. The report from the Committee is now undergoing a formal hearing process. Based on the Committees recommendation and comments during the hearing the responsible Ministry will take a decision on future infrastructure in Norway for the spent nuclear fuel. This will be decisive for the future management of spent nuclear fuel and radioactive waste in Norway. (author)

The evaluation of environmental effects of nuclear power plants

International Nuclear Information System (INIS)

Oezyurt, M.; Iyit, L.; Seyitogullari, S.

2006-01-01

Energy is today one of the most significant topics in the world. Humans are investigating alternative energy resources due to the fossil energy sources to be exhausted in future. As known, the life of energy resources such as coal and oil is limited. Natural gas will cover the need just for a limited period. On the other hand, developing population will increase the need of energy for the next generation. Therefore, alternative energy has gained much significance in recent years. Nuclear energy is the most criticized energy in public opinion. About 17 pct. of the electric need in the world is being covered by nuclear power plants . This ratio is over 30 pct. in European Union and over 78.2 pct. in France. The most significant risk as regard with environmental pollution is radioactive wastes for these plants. The opposite sides towards nuclear energy claim about the accidents of nuclear power plants and deaths in short and long terms. As long as the security rules are applied, nuclear power plants affect neither human nor environmental health in a detrimental way. The radiation emission scattered by nuclear power plants is very low. In this work, first of all nuclear energy was evaluated from a standpoint of environmental pollution and both positive and negative effects were investigated. As a result, the humanity will have to benefit from all the alternative energy resources , the nuclear energy as well, in order not to live in a dark world. Every technology has its own risks. It seems that if nuclear energy power plants are operated in high technology conditions it will be un given up for humanity

Evaluation of CMIP5 models for projection of future precipitation change in Bornean tropical rainforests

Science.gov (United States)

Hussain, Mubasher; Yusof, Khamaruzaman Wan; Mustafa, Muhammad Raza Ul; Mahmood, Rashid; Jia, Shaofeng

2017-10-01

We present the climate change impact on the annual and seasonal precipitation over Rajang River Basin (RRB) in Sarawak by employing a set of models from Coupled Model Intercomparison Project Phase 5 (CMIP5). Based on the capability to simulate the historical precipitation, we selected the three most suitable GCMs (i.e. ACCESS1.0, ACCESS1.3, and GFDL-ESM2M) and their mean ensemble (B3MMM) was used to project the future precipitation over the RRB. Historical (1976-2005) and future (2011-2100) precipitation ensembles of B3MMM were used to perturb the stochastically generated future precipitation over 25 rainfall stations in the river basin. The B3MMM exhibited a significant increase in precipitation during 2080s, up to 12 and 8% increase in annual precipitation over upper and lower RRB, respectively, under RCP8.5, and up to 7% increase in annual precipitation under RCP4.5. On the seasonal scale, Mann-Kendal trend test estimated statistically significant positive trend in the future precipitation during all seasons; except September to November when we only noted significant positive trend for the lower RRB under RCP4.5. Overall, at the end of the twenty-first century, an increase in annual precipitation is noteworthy in the whole RRB, with 7 and 10% increase in annual precipitation under the RCP4.5 and the RCP8.5, respectively.

'The End of Sitting' : An Empirical Study on Working in an Office of the Future

NARCIS (Netherlands)

Withagen, Rob; Caljouw, Simone R.

Background Inspired by recent findings that prolonged sitting has detrimental health effects, Rietveld Architecture Art Affordances (RAAAF) and visual artist Barbara Visser designed a working environment without chairs and desks. This environment, which they called The End of Sitting, is a sculpture

SU-D-BRD-02: A Web-Based Image Processing and Plan Evaluation Platform (WIPPEP) for Future Cloud-Based Radiotherapy

International Nuclear Information System (INIS)

Chai, X; Liu, L; Xing, L

2014-01-01

Purpose: Visualization and processing of medical images and radiation treatment plan evaluation have traditionally been constrained to local workstations with limited computation power and ability of data sharing and software update. We present a web-based image processing and planning evaluation platform (WIPPEP) for radiotherapy applications with high efficiency, ubiquitous web access, and real-time data sharing. Methods: This software platform consists of three parts: web server, image server and computation server. Each independent server communicates with each other through HTTP requests. The web server is the key component that provides visualizations and user interface through front-end web browsers and relay information to the backend to process user requests. The image server serves as a PACS system. The computation server performs the actual image processing and dose calculation. The web server backend is developed using Java Servlets and the frontend is developed using HTML5, Javascript, and jQuery. The image server is based on open source DCME4CHEE PACS system. The computation server can be written in any programming language as long as it can send/receive HTTP requests. Our computation server was implemented in Delphi, Python and PHP, which can process data directly or via a C++ program DLL. Results: This software platform is running on a 32-core CPU server virtually hosting the web server, image server, and computation servers separately. Users can visit our internal website with Chrome browser, select a specific patient, visualize image and RT structures belonging to this patient and perform image segmentation running Delphi computation server and Monte Carlo dose calculation on Python or PHP computation server. Conclusion: We have developed a webbased image processing and plan evaluation platform prototype for radiotherapy. This system has clearly demonstrated the feasibility of performing image processing and plan evaluation platform through a web

SU-D-BRD-02: A Web-Based Image Processing and Plan Evaluation Platform (WIPPEP) for Future Cloud-Based Radiotherapy

Energy Technology Data Exchange (ETDEWEB)

Chai, X; Liu, L; Xing, L [Stanford UniversitySchool of Medicine, Stanford, CA (United States)

2014-06-01

Purpose: Visualization and processing of medical images and radiation treatment plan evaluation have traditionally been constrained to local workstations with limited computation power and ability of data sharing and software update. We present a web-based image processing and planning evaluation platform (WIPPEP) for radiotherapy applications with high efficiency, ubiquitous web access, and real-time data sharing. Methods: This software platform consists of three parts: web server, image server and computation server. Each independent server communicates with each other through HTTP requests. The web server is the key component that provides visualizations and user interface through front-end web browsers and relay information to the backend to process user requests. The image server serves as a PACS system. The computation server performs the actual image processing and dose calculation. The web server backend is developed using Java Servlets and the frontend is developed using HTML5, Javascript, and jQuery. The image server is based on open source DCME4CHEE PACS system. The computation server can be written in any programming language as long as it can send/receive HTTP requests. Our computation server was implemented in Delphi, Python and PHP, which can process data directly or via a C++ program DLL. Results: This software platform is running on a 32-core CPU server virtually hosting the web server, image server, and computation servers separately. Users can visit our internal website with Chrome browser, select a specific patient, visualize image and RT structures belonging to this patient and perform image segmentation running Delphi computation server and Monte Carlo dose calculation on Python or PHP computation server. Conclusion: We have developed a webbased image processing and plan evaluation platform prototype for radiotherapy. This system has clearly demonstrated the feasibility of performing image processing and plan evaluation platform through a web

The TENDL library: Hope, reality and future

Directory of Open Access Journals (Sweden)

Rochman D.

2017-01-01

Full Text Available The TALYS Evaluated Nuclear Data Library (TENDL has now 8 releases since 2008. Considerable experience has been acquired for the production of such general-purpose nuclear data library based on the feedback from users, evaluators and processing experts. The backbone of this achievement is simple and robust: completeness, quality and reproducibility. If TENDL is extensively used in many fields of applications, it is necessary to understand its strong points and remaining weaknesses. Alternatively, the essential knowledge is not the TENDL library itself, but rather the necessary method and tools, making the library a side product and focusing the efforts on the evaluation knowledge. The future of such approach will be discussed with the hope of nearby greater success.

The Future Multiple

DEFF Research Database (Denmark)

Spaniol, Matthew Jon; Rowland, Nicholas James

2015-01-01

/value – The original contribution is in demonstrating how plural futures and the singular future co-exist in practice. Thus, an eclipse of the future by futures can only ever be partial. For “futures” to be conceptually potent, “the future” must be at least provisionally believable and occasionally useful. Otherwise......, if “the future” were so preposterous an idea, then “futures” would cease to be a critical alternative to it. Futures needs the future; they are relationally bound together in a multiplicity. This paper considers what such a logical reality implies for a field that distances itself from the future and self......). Multiplicity, as a post-ANT sensibility, helps one make sense of the empirical materials. This paper examines the possibility that rather than being alternatives to one another, plural futures and the singular future might co-exist in practice, and, thus, constitute a multiplicity. Design...

Review & Analysis: Technological Impact on Future Air Force Personnel & Training: Distributed Collaborative Decision-Making, Volume I

National Research Council Canada - National Science Library

Palmer, Barbara

1997-01-01

..., compared to that of a single individual. (2) The greatest detriment to collaborative distributed decision making is that we must rely on technology rather than face to face interactions, and subtleties of human communication may be lost. (3...

Antimicrobial stewardship in long-term care facilities in Belgium: a questionnaire-based survey of nursing homes to evaluate initiatives and future developments

Directory of Open Access Journals (Sweden)

François Kidd

2016-03-01

Full Text Available Abstract Background The use of antimicrobials is intense and often inappropriate in long-term care facilities. Antimicrobial resistance has increased in acute and chronic care facilities, including those in Belgium. Evidence is lacking concerning antimicrobial stewardship programmes in chronic care settings. The medical coordinator practicing in Belgian nursing homes is a general practitioner designated to coordinate medical activity. He is likely to be the key position for effective implementation of such programmes. The aim of this study was to evaluate past, present, and future developments of antimicrobial stewardship programmes by surveying medical coordinators working in long-term care facilities in Belgium. Methods We conducted an online questionnaire-based survey of 327 Belgian medical coordinators. The questionnaire was composed of 33 questions divided into four sections: characteristics of the respondents, organisational frameworks for implementation of the antimicrobial stewardship programme, tools to promote appropriate antimicrobial use and priorities of action. Questions were multiple choice, rating scale, or free text. Results A total of 39 medical coordinators (12 % completed the questionnaire. Past or present antimicrobial stewardship initiatives were reported by 23 % of respondents. The possibility of future developments was rated 2.7/5. The proposed key role of medical coordinators was rated <3/5 by 36 % of respondents. General practitioners, nursing staff, and hospital specialists are accepted as important roles. The use of antimicrobial guidelines was reported by only 19 % of respondents. Education was considered the cornerstone for any future developments. Specific diagnostic recommendations were considered useful, but chest x-rays were judged difficult to undertake. The top priority identified was to reduce unnecessary treatment of asymptomatic urinary infections. Conclusions Our study shows that the implementation of

Future Professional Communication in Astronomy II

Science.gov (United States)

Accomazzi, Alberto

The present volume gathers together the talks presented at the second colloquium on the Future Professional Communication in Astronomy (FPCAII), held at the Harvard-Smithsonian Center for Astrophysics (Cambridge, MA) on 13-14 April 2010. This meeting provided a forum for editors, publishers, scientists, librarians and officers of learned societies to discuss the future of the field. The program included talks from leading researchers and practitioners and drew a crowd of approximately 50 attendees from 10 countries. These proceedings contain contributions from invited and contributed talks from leaders in the field, touching on a number of topics. Among them: The role of disciplinary repositories such as ADS and arXiv in astronomy and the physical sciences; Current status and future of Open Access Publishing models and their impact on astronomy and astrophysics publishing; Emerging trends in scientific article publishing: semantic annotations, multimedia content, links to data products hosted by astrophysics archives; Novel approaches to the evaluation of facilities and projects based on bibliometric indicators; Impact of Government mandates, Privacy laws, and Intellectual Property Rights on the evolving digital publishing environment in astronomy; Communicating astronomy to the public: the experience of the International Year of Astronomy 2009.

Temperature response to future urbanization and climate change

Science.gov (United States)

Argüeso, Daniel; Evans, Jason P.; Fita, Lluís; Bormann, Kathryn J.

2014-04-01

This study examines the impact of future urban expansion on local near-surface temperature for Sydney (Australia) using a future climate scenario (A2). The Weather Research and Forecasting model was used to simulate the present (1990-2009) and future (2040-2059) climates of the region at 2-km spatial resolution. The standard land use of the model was replaced with a more accurate dataset that covers the Sydney area. The future simulation incorporates the projected changes in the urban area of Sydney to account for the expected urban expansion. A comparison between areas with projected land use changes and their surroundings was conducted to evaluate how urbanization and global warming will act together and to ascertain their combined effect on the local climate. The analysis of the temperature changes revealed that future urbanization will strongly affect minimum temperature, whereas little impact was detected for maximum temperature. The minimum temperature changes will be noticeable throughout the year. However, during winter and spring these differences will be particularly large and the increases could be double the increase due to global warming alone at 2050. Results indicated that the changes were mostly due to increased heat capacity of urban structures and reduced evaporation in the city environment.

Varicocele and testicular function

Directory of Open Access Journals (Sweden)

Alexander W Pastuszak

2015-01-01

Full Text Available Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility. Significant study has clarified the negative impact of varicocele on semen parameters and more recent work has shed light on its detrimental effects on the molecular and ultrastructural features of sperm and the testicular microenvironment, as well as more clearly defined the positive impacts of treatment on couples′ fertility. The relationship between varicocele and testicular endocrine function, while known for some time based on histologic evaluation, has become more apparent in the clinical setting with a growing link between varicocele and hypogonadism. Finally, in the pediatric setting, while future study will clarify the impact of varicocele on fertility and testicular function, recent work supports a parallel effect of varicocele in adolescents and adults, suggesting a re-evaluation of current treatment approaches in light of the progressive nature of the condition and potential increased risk of future disease.

Evaluating impacts of climate change on future water scarcity in an intensively managed semi-arid region using a coupled model of biophysical processes and water rights

Science.gov (United States)

Han, B.; Flores, A. N.; Benner, S. G.

2017-12-01

In semiarid and arid regions where water supply is intensively managed, future water scarcity is a product of complex interactions between climate change and human activities. Evaluating future water scarcity under alternative scenarios of climate change, therefore, necessitates modeling approaches that explicitly represent the coupled biophysical and social processes responsible for the redistribution of water in these regions. At regional scales a particular challenge lies in adequately capturing not only the central tendencies of change in projections of climate change, but also the associated plausible range of variability in those projections. This study develops a framework that combines a stochastic weather generator, historical climate observations, and statistically downscaled General Circulation Model (GCM) projections. The method generates a large ensemble of daily climate realizations, avoiding deficiencies of using a few or mean values of individual GCM realizations. Three climate change scenario groups reflecting the historical, RCP4.5, and RCP8.5 future projections are developed. Importantly, the model explicitly captures the spatiotemporally varying irrigation activities as constrained by local water rights in a rapidly growing, semi-arid human-environment system in southwest Idaho. We use this modeling framework to project water use and scarcity patterns under the three future climate change scenarios. The model is built using the Envision alternative futures modeling framework. Climate projections for the region show future increases in both precipitation and temperature, especially under the RCP8.5 scenario. The increase of temperature has a direct influence on the increase of the irrigation water use and water scarcity, while the influence of increased precipitation on water use is less clear. The predicted changes are potentially useful in identifying areas in the watershed particularly sensitive to water scarcity, the relative importance of

A fear index to predict oil futures returns

International Nuclear Information System (INIS)

Chevallier, Julien; Sevi, Benoit

2013-01-01

This paper evaluates the predictability of WTI light sweet crude oil futures by using the variance risk premium, i.e. the difference between model-free measures of implied and realized volatilities. Additional regressors known for their ability to explain crude oil futures prices are also considered, capturing macro-economic, financial and oil-specific influences. The results indicate that the explanatory power of the (negative) variance risk premium on oil excess returns is particularly strong (up to 25% for the adjusted R-squared across our regressions). It complements other financial (e.g. default spread) and oil-specific (e.g. US oil stocks) factors highlighted in previous literature. (authors)

Nuclear power. What policies for what future

International Nuclear Information System (INIS)

Thiriet, Lucien.

1976-01-01

A long- and very long-dated estimation of the world uranium resources are given comparatively to that of fissile energies, and the short- and mean-dated distributions of these resources and uranium economy are discussed in the light of foresights concerning the energy consumption provided for France and the most important industrial countries in 1985. The competitive character and the economic future of nuclear power are discussed. The incidence that the evolution in the nuclear policies of the principal industrial countries had, in the past, on the formation and growth of the market of nuclear power production is shown. The future possibilities of nuclear reactors and nuclear hydrogen are evaluated with the role of nuclear power in an economic policy in national independence [fr

Ultraviolet radiation, measurements and safety evaluations for radiation protection purposes

International Nuclear Information System (INIS)

Witew, B.; Fischer, P.G.

1983-01-01

In order to evaluate the effects of ultraviolet radiation, one has to study that photobiologically effective radiation which induces a just measurable threshold reaction. For practical radiation protection, one has to determine the permissible duration of exposure at the end of which the threshold reaction is induced. This time limit is derived by means of spectral measurements and determination of radiation intensity. Detrimental photobiological effects can be avoided, and favourable effects optimized, by observing the time limit. Thus these measurements are used to determine the threshold at which the desired effects of ultraviolet radiation will be accompanied by unwanted effects or damage to persons, as for instance in the use of ultraviolet radiation for operating room sterilization, arc welding work, or cosmetic purposes. (orig.) [de

Future changes in large-scale transport and stratosphere-troposphere exchange

Science.gov (United States)

Abalos, M.; Randel, W. J.; Kinnison, D. E.; Garcia, R. R.

2017-12-01

Future changes in large-scale transport are investigated in long-term (1955-2099) simulations of the Community Earth System Model - Whole Atmosphere Community Climate Model (CESM-WACCM) under an RCP6.0 climate change scenario. We examine artificial passive tracers in order to isolate transport changes from future changes in emissions and chemical processes. The model suggests enhanced stratosphere-troposphere exchange in both directions (STE), with decreasing tropospheric and increasing stratospheric tracer concentrations in the troposphere. Changes in the different transport processes are evaluated using the Transformed Eulerian Mean continuity equation, including parameterized convective transport. Dynamical changes associated with the rise of the tropopause height are shown to play a crucial role on future transport trends.

Oversimplification in the study of emotional memory

Science.gov (United States)

Bennion, Kelly A.; Ford, Jaclyn H.; Murray, Brendan D.; Kensinger, Elizabeth A.

2014-01-01

This Short Review critically evaluates three hypotheses about the effects of emotion on memory: First, emotion usually enhances memory. Second, when emotion does not enhance memory, this can be understood by the magnitude of physiological arousal elicited, with arousal benefiting memory to a point but then having a detrimental influence. Third, when emotion facilitates the processing of information, this also facilitates the retention of that same information. For each of these hypotheses, we summarize the evidence consistent with it, present counter-evidence suggesting boundary conditions for the effect, and discuss the implications for future research. PMID:24007950

Transformation of Agricultural Land for Urbanisation, Infrastructural Development and Question of Future Food Security: Cases from Parts of Hugli District, West Bengal

Directory of Open Access Journals (Sweden)

Giyasuddin Siddique

2017-11-01

Full Text Available Developing countries of the world encounter urbanisation and infrastructural development in or around the fertile tracts and the absence of any landuse plan for desired land use change has led to conversion of farmlands, which is detrimental to future food security and environmental quality. Hugli district is traditionally well known as one of the most prosperous agricultural regions of West Bengal but the district is experiencing rapid urban extension and infrastructural development towards productive agricultural land since 1991. This has caused decline in the amount of agricultural production which may be treated as an indicator of increasing threat to the long run sustainable livelihood security of the people of the whole of West Bengal. This article critically explores the transformation of agricultural (farm land because of growing rate of urbanisation and infrastructural development, which in turn poses the question of threat to food (in security. Although, this is a growing problem across the universe, this article probes the future food security questions of Hugli district, West Bengal by examining the impact of the highly intertwined indicators of urbanisation and infrastructural development on agricultural (farm land use and its effect on food security. Regression analysis, Spearman’s Ranking Correlation Coefficient, Remote Sensing technologies, Markov Chain Model, Projection of future population growth and yield rate are employed to understand the depth of the problem. The result not only shows a direct negative correlation between urban extension and agricultural areal contraction but also the supervised classification of satellite imageries shows that there is rapid change of rural land use from 1996-2016. There is no match between future population growth and future yield rate of crops and the Markov Chain Model further predicts that the cropland will decrease from 62.77% to 42.90% and the built up area will increase from 31

Multifactor valuation models of energy futures and options on futures

Science.gov (United States)

Bertus, Mark J.

The intent of this dissertation is to investigate continuous time pricing models for commodity derivative contracts that consider mean reversion. The motivation for pricing commodity futures and option on futures contracts leads to improved practical risk management techniques in markets where uncertainty is increasing. In the dissertation closed-form solutions to mean reverting one-factor, two-factor, three-factor Brownian motions are developed for futures contracts. These solutions are obtained through risk neutral pricing methods that yield tractable expressions for futures prices, which are linear in the state variables, hence making them attractive for estimation. These functions, however, are expressed in terms of latent variables (i.e. spot prices, convenience yield) which complicate the estimation of the futures pricing equation. To address this complication a discussion on Dynamic factor analysis is given. This procedure documents latent variables using a Kalman filter and illustrations show how this technique may be used for the analysis. In addition, to the futures contracts closed form solutions for two option models are obtained. Solutions to the one- and two-factor models are tailored solutions of the Black-Scholes pricing model. Furthermore, since these contracts are written on the futures contracts, they too are influenced by the same underlying parameters of the state variables used to price the futures contracts. To conclude, the analysis finishes with an investigation of commodity futures options that incorporate random discrete jumps.

Effect of combined loading on pipe flaw evaluation criteria

International Nuclear Information System (INIS)

Miura, Naoki; Chung Yeonki

1999-01-01

Considering a rational maintenance rule of Light Water Reactor piping, reliable flaw evaluation criteria are essential to determine how a detected flaw is detrimental to continuous plant operation. Ductile fracture is one of the dominant failure modes to be considered for carbon steel piping, and can be analyzed by the elastic-plastic fracture mechanics. Currently the analytical results are provided as flaw evaluation criteria using load correction factors such like the Z-factor in ASME Code Section 6. The present correction factors were conventionally determined taken a conservatism and a simplicity into account, however, the effect of internal pressure which would be an important factor under an actual plant condition was not adequately considered. Recently, a J-estimation scheme, 'LBB.ENGC' for ductile fracture analysis of circumferentially through-wall-cracked pipes subjected to combined loading was newly developed to have a better prediction with more realistic manner. This method is explicitly incorporated the contribution of both bending and tension due to internal pressure by means of the scheme compatible with an arbitrary combined loading history. In this paper, the effect of internal pressure on the flaw evaluation criteria was investigated using the new J-estimation scheme. A correction factor based on the new J-estimation scheme was compared with the present correction factors, and the predictability of the current flaw evaluation criteria was quantitatively evaluated in consideration of internal pressure. (author)

Coastal flooding in Denmark – future outlook

DEFF Research Database (Denmark)

Sørensen, C.; Knudsen, P.; Andersen, O. B.

2014-01-01

Water loading from all directions due to river discharge, precipitation, groundwater and the sea state (i.e. mean and extreme water levels) need to be carefully considered when dealing with flooding hazards at the coast. Flooding hazard and risk mapping are major topics in low-lying coastal are- ...... this knowledge together to enable a practice-oriented methodology that combines their effects and future sea extremes in hazard and risk mapping and climate change adaptation schemes in Denmark......- as before even considering the adverse effects of climate change and sea level rise (SLR). From an assessment of Danish sea extremes from historical evidence, tide gauge series, and space measurements, we discuss the current and future hazards, exposure, and vulnerability to flooding along the diverse......, land-use, protection measures a.o. that must be taken into account in order to evaluate current and future flooding hazards and management options. We provide examples from Danish case-studies underlining the necessity of including these factors and we outline an interdisciplinary approach to bring...

Forest Products Industry of the Future

Energy Technology Data Exchange (ETDEWEB)

Los Alamos Technical Associates, Inc

2002-05-01

Los Alamos Technical Associates, Inc (LATA) conducted an evaluation of the potential impact and value of a portion of the current portfolio of r&d projects supported by the Office of Industrial Technology and the Forest Products Industry of the Future. The mission of the evaluation was to (a) assess the potential impact of the projects to meet the critical goals of the industry as identified in the vision and roadmapping documents. (b) Evaluate the relationship between the current portfolio of projects and the Agenda 202 Implementation Plan. In addition, evaluate the relationship between the portfolio and the newly revised draft technology strategy being created by the industry. (c) Identify areas where current efforts are making significant progress towards meeting industry goals and identify areas where additional work my be required to meet these goals. (d) Make recommendations to the DOE and the Forest Products Industry on possible improvements in the portfolio and in the current methodology that DOE uses to assess potential impacts on its R&D activities.

Human factors measurement for future air traffic control systems.

Science.gov (United States)

Langan-Fox, Janice; Sankey, Michael J; Canty, James M

2009-10-01

This article provides a critical review of research pertaining to the measurement of human factors (HF) issues in current and future air traffic control (ATC). Growing worldwide air traffic demands call for a radical departure from current ATC systems. Future systems will have a fundamental impact on the roles and responsibilities of ATC officers (ATCOs). Valid and reliable methods of assessing HF issues associated with these changes, such as a potential increase (or decrease) in workload, are of utmost importance for advancing theory and for designing systems, procedures, and training. We outline major aviation changes and how these relate to five key HF issues in ATC. Measures are outlined, compared, and evaluated and are followed by guidelines for assessing these issues in the ATC domain. Recommendations for future research are presented. A review of the literature suggests that situational awareness and workload have been widely researched and assessed using a variety of measures, but researchers have neglected the areas of trust, stress, and boredom. We make recommendations for use of particular measures and the construction of new measures. It is predicted that, given the changing role of ATCOs and profound future airspace requirements and configurations, issues of stress, trust, and boredom will become more significant. Researchers should develop and/or refine existing measures of all five key HF issues to assess their impact on ATCO performance. Furthermore, these issues should be considered in a holistic manner. The current article provides an evaluation of research and measures used in HF research on ATC that will aid research and ATC measurement.

Mechanical property, biocorrosion and in vitro biocompatibility evaluations of Mg-Li-(Al)-(RE) alloys for future cardiovascular stent application.

Science.gov (United States)

Zhou, W R; Zheng, Y F; Leeflang, M A; Zhou, J

2013-11-01

Mg-Li-based alloys were investigated for future cardiovascular stent application as they possess excellent ductility. However, Mg-Li binary alloys exhibited reduced mechanical strengths due to the presence of lithium. To improve the mechanical strengths of Mg-Li binary alloys, aluminum and rare earth (RE) elements were added to form Mg-Li-Al ternary and Mg-Li-Al-RE quarternary alloys. In the present study, six Mg-Li-(Al)-(RE) alloys were fabricated. Their microstructures, mechanical properties and biocorrosion behavior were evaluated by using optical microscopy, X-ray diffraction, scanning electronic microscopy, tensile tests, immersion tests and electrochemical measurements. Microstructure characterization indicated that grain sizes were moderately refined by the addition of rare earth elements. Tensile testing showed that enhanced mechanical strengths were obtained, while electrochemical and immersion tests showed reduced corrosion resistance caused by intermetallic compounds distributed throughout the magnesium matrix in the rare-earth-containing Mg-Li alloys. Cytotoxicity assays, hemolysis tests as well as platelet adhesion tests were performed to evaluate in vitro biocompatibilities of the Mg-Li-based alloys. The results of cytotoxicity assays clearly showed that the Mg-3.5Li-2Al-2RE, Mg-3.5Li-4Al-2RE and Mg-8.5Li-2Al-2RE alloys suppressed vascular smooth muscle cell proliferation after 5day incubation, while the Mg-3.5Li, Mg-8.5Li and Mg-8.5Li-1Al alloys were proven to be tolerated. In the case of human umbilical vein endothelial cells, the Mg-Li-based alloys showed no significantly reduced cell viabilities except for the Mg-8.5Li-2Al-2RE alloy, with no obvious differences in cell viability between different culture periods. With the exception of Mg-8.5Li-2Al-2RE, all of the other Mg-Li-(Al)-(RE) alloys exhibited acceptable hemolysis ratios, and no sign of thrombogenicity was found. These in vitro experimental results indicate the potential of Mg

Vulnerability of Water Resources under Climate and Land Use Change: Evaluation of Present and Future Threats for Austria

Science.gov (United States)

Nachtnebel, Hans-Peter; Wesemann, Johannes; Herrnegger, Mathew; Senoner, Tobias; Schulz, Karsten

2015-04-01

vulnerability were developed. A comparison with existing data (River Basin Management Plan and Groundwater Chemistry Regulation) shows a good agreement between the elaborated maps and observations for the present state. The Overall Vulnerability is very low and low for most parts of Austria, especially in the forested alpine region. Bigger cities like Vienna, Graz and Linz show medium vulnerabilities, due to the high water demand and low ecosystem services. Only in the north-eastern and south-eastern part of the country some water supply associations with high and very high overall vulnerability exist. Groundwater recharge is quite small in these regions and the water quality is limited due to intense agriculture and possible threats through landfills. The developed framework allows an evaluation of water quantity and quality vulnerabilities for large scales for the present and the future. Including ecosystem services and gross value added an overall vulnerability can be determined.

Contemporary and future insights into fertility preservation in male cancer patients

OpenAIRE

Agarwal, Ashok; Ong, Chloe; Durairajanayagam, Damayanthi

2014-01-01

In recent years, survival rates of cancer patients have increased, resulting in a shift of focus from quantity to quality of life. A key aspect of quality of life is fertility potential; patients suffering from iatrogenic infertility often become depressed. Since many cancer therapies?chemotherapy, radiotherapy and/or surgery?and even cancer itself have detrimental effects on the male reproductive system, it is important to preserve fertility before any treatment commences. Currently, the onl...

Evaluating the beneficial and detrimental effects of bile pigments in early and later life

Directory of Open Access Journals (Sweden)

Phyllis A. Dennery

2012-06-01

Full Text Available The heme degradation pathway has been conserved throughout phylogeny and allows for the removal of a pro-oxidant and the generation of unique molecules including bile pigment with important cellular functions. The impact of bile pigments on health and disease are reviewed as is the special circumstance of neonatal hyperbilirubinemia. In addition, the importance of promoter polymorphisms in the UDP-glucuronyltransferase gene (UGTA1, which is key to the elimination of excess bilirubin and to preventing its toxicity, are discussed. Overall, the duality of bile pigments as either cytoprotective or toxic molecules is highlighted.

ANALYSIS OF EXPECTED PRICE DYNAMICS BETWEEN FLUID MILK FUTURES CONTRACTS AND CASH PRICES FOR FLUID MILK

OpenAIRE

T. Randall FORTENBERY; Robert A. CROPP; Hector O. ZAPATA

1997-01-01

The objective of this study is to provide an empirical evaluation of the expected relationship between cash and futures prices for fluid milk. This is done using historic cash prices from 1988 to 1995, and making inferences about how futures prices would have behaved if they had traded during this sample period. Futures prices are simulated over the sample period based on two assumptions about futures market behavior for fluid milk. The first is that the futures market will essentially price ...

Review on the Projections of Future Storminess over the North Atlantic European Region

Directory of Open Access Journals (Sweden)

Tina Mölter

2016-04-01

Full Text Available This is an overview of the results from previously published climate modeling studies reporting on projected aspects of future storminess over the North Atlantic European region (NAER in the period 2020–2190. Changes in storminess are summarized for seven subregions in the study area and rated by a categorical evaluation scheme that takes into account emission scenarios and modeling complexity in the reviewed studies. Although many of the reviewed studies reported an increase in the intensity of high-impact wind speed and extreme cyclone frequency in the second half of the 21st century, the projections of aspects of future storminess over the NAER differed regionally. There is broad consensus that the frequency and intensity of storms, cyclones, and high-impact wind speed will increase over Central and Western Europe, and these changes will probably have the potential to produce more damage. In contrast, future extratropical storminess over Southern Europe is very likely to decrease. For Northern and Eastern Europe the results of the evaluation are inconclusive, because there is an indication of increasing as well as decreasing development of the evaluated aspects of future storminess. Concerning the storm track, we found indications of a likely north- and eastward shift in most assessed studies. Results from three studies suggest a northeastward shift of the North Atlantic Oscillation.

Eying the future: Eye movement in past and future thinking.

Science.gov (United States)

El Haj, Mohamad; Lenoble, Quentin

2017-06-07

We investigated eye movement during past and future thinking. Participants were invited to retrieve past events and to imagine future events while their scan path was recorded by an eye-tracker. Past thinking triggered more fixation (p thinking. Past and future thinking triggered a similar duration of fixations and saccades, as well as a similar amplitude of saccades. Interestingly, participants rated past thinking as more vivid than future thinking (p thinking seems to be accompanied by an increased number of fixations and saccades. Fixations and saccades in past thinking can be interpreted as an attempt by the visual system to find (through saccades) and activate (through fixations) stored memory representations. The same interpretation can be applied to future thinking as this ability requires activation of past experiences. However, future thinking triggers fewer fixations and saccades than past thinking: this may be due to its decreased demand on visual imagery, but could also be related to a potentially deleterious effect of eye movements on spatial imagery required for future thinking. Copyright © 2017 Elsevier Ltd. All rights reserved.

Resolving contradictions in boundedly rational search: How strategists weigh contradictory beliefs to evaluate conjectures about the future

DEFF Research Database (Denmark)

Ehrig, Timo; Schmidt, Jens

2018-01-01

When strategists form conjectures about the future (such as whether a technol- ogy will solve a particular problem or what will be future sources of competitive advantage) they typically face multiple plausible but mutually contradictory possi- bilities, as the future may unfold in a myriad...... as ”un- willingness to give up”. Our results provide for a mechanism that allows managers to economize on their cognitive resources when resolving contradictions, and they also show that how managers resolve contradictions provides direction for their fur- ther search process. We develop propositions...... that are empirically testable and thus allow identifying boundary conditions of our results, and we discuss how our results may be useful to managers and teachers....

Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes.

Science.gov (United States)

Stringer, Megan; Abeysekera, Irushi; Thomas, Jared; LaCombe, Jonathan; Stancombe, Kailey; Stewart, Robert J; Dria, Karl J; Wallace, Joseph M; Goodlett, Charles R; Roper, Randall J

2017-08-01

Down syndrome (DS) is caused by three copies of human chromosome 21 (Hsa21) and results in phenotypes including intellectual disability and skeletal deficits. Ts65Dn mice have three copies of ~50% of the genes homologous to Hsa21 and display phenotypes associated with DS, including cognitive deficits and skeletal abnormalities. DYRK1A is found in three copies in humans with Trisomy 21 and in Ts65Dn mice, and is involved in a number of critical pathways including neurological development and osteoclastogenesis. Epigallocatechin-3-gallate (EGCG), the main polyphenol in green tea, inhibits Dyrk1a activity. We have previously shown that EGCG treatment (~10mg/kg/day) improves skeletal abnormalities in Ts65Dn mice, yet the same dose, as well as ~20mg/kg/day did not rescue deficits in the Morris water maze spatial learning task (MWM), novel object recognition (NOR) or balance beam task (BB). In contrast, a recent study reported that an EGCG-containing supplement with a dose of 2-3mg per day (~40-60mg/kg/day) improved hippocampal-dependent task deficits in Ts65Dn mice. The current study investigated if an EGCG dosage similar to that study would yield similar improvements in either cognitive or skeletal deficits. Ts65Dn mice and euploid littermates were given EGCG [0.4mg/mL] or a water control, with treatments yielding average daily intakes of ~50mg/kg/day EGCG, and tested on the multivariate concentric square field (MCSF)-which assesses activity, exploratory behavior, risk assessment, risk taking, and shelter seeking-and NOR, BB, and MWM. EGCG treatment failed to improve cognitive deficits; EGCG also produced several detrimental effects on skeleton in both genotypes. In a refined HPLC-based assay, its first application in Ts65Dn mice, EGCG treatment significantly reduced kinase activity in femora but not in the cerebral cortex, cerebellum, or hippocampus. Counter to expectation, 9-week-old Ts65Dn mice exhibited a decrease in Dyrk1a protein levels in Western blot analysis

Making the future palpable: Notes from a major incident Future Laboratory

DEFF Research Database (Denmark)

Büscher, Monika; Kristensen, Margit; Mogensen, Preben Holst

2008-01-01

In this paper we describe experiences from a Future Laboratory. Future laboratories allow users to experiment with prototypes of future technologies in as realistic as possible conditions. We have devised this method because, to realize the potential of advanced ubiquitous computing technologies...... it is essential to anticipate and design for future practices, but for prospective users it is often difficult to imagine and articulate future practices and provide design specifications. However, they readily invent new ways of working in engagement with new technologies and, by facilitating realistic use...... of prototype technologies in Future Laboratories, designers and users can define and study both opportunities and constraints for design. We present 11 scenes from a Major Incidents Future Laboratory held in September 2005. Many raise tough questions rather than provide quick answers. In addition, many also...

Original article Future perspectives as a condition of positive adaptation of young adults after traumatic experience

Directory of Open Access Journals (Sweden)

Marzanna Farnicka

2014-10-01

Full Text Available Background The paper presents the results of a study on the possible role of sense of influencing one’s life and expectations towards the future as a personal condition of adaptation. In accordance with the theory of formulation of temporal perspectives, these variables were assumed to be related to construction of the psychological reality of the subjects. Participants and procedure The study involved 162 adults in two groups, with traumatic experience and without such experience, aged 18-35. The tools used in the study included: Rosenberg Self-Esteem Scale (SES, Boszkiewicz Questionnaire: Life Experience Questionnaire, events evaluation and expectations of changes in the future. Results The study revealed significant differences between people from the two groups in the scope of self-evaluation, sense of influence on events and future expectations. Conclusions The results pointed to the need for adjustment of therapeutic and preventive treatment to future expectations, evaluation of events and the current stage of development, as indicated by personal conditions of adaptation.

Micronesian agroforestry: evidence from the past, implications for the future

Science.gov (United States)

Marjorie V. C. Falanruw

1993-01-01

Traditional agroforest systems exist throughout Micronesia. The system found on one Micronesian group of islands, Yap, is described and evaluated in ecological terms. Implications for future development of agriculture in Micronesia are discussed and some specific recommendations are given.

Development of a web-based fatigue life evaluation system for primary components in a nuclear power plant

International Nuclear Information System (INIS)

Seo, Hyong Won; Lee, Sang Min; Choi, Jae Boong; Kim, Young Jin; Choi, Sung Nam; Jang, Ki Sang; Hong, Sung Yull

2004-01-01

A nuclear power plant is composed of a number of primary components. Maintaining the integrity of these components is one of the most critical issues in nuclear industry. In order to maintain the integrity of these primary components, a complicated procedure is required including regular in-service inspection, failure assessment, fracture mechanics analysis, etc. Also, experts in different fields have to co-operate to resolve the integrity issues on the basis of inspection results. This integrity evaluation process usually takes long, and thus, is detrimental for the plant productivity. Therefore, an effective safety evaluation system is essential to manage the integrity issues on a nuclear power plant. In this paper, a web-based fatigue life evaluation system for primary components in nuclear power plant is proposed. This system provides engineering knowledge-based information and concurrent and collaborative working environment through internet, and thus, is expected to raise the efficiency of integrity evaluation procedures on primary components of a nuclear power plant

[Evaluation of special GP-centered health care contracts in Germany by the participating GPs. present situation and future perspectives].

Science.gov (United States)

Klingenberg, Anja; Broge, Björn; Herholz, Harald; Szecsenyi, Joachim; Ose, Dominik

2010-02-01

In 2004, German statutory health care funds were given the possibility to offer their insured a special general practitioner-( GP-)centered health care contract (HZV), since 2007 they are obliged to do so. The aim of these contracts is to strengthen the role of the GP as a coordinator in the health care system. Until now, the evidence regarding the GPs' view on these contracts is poor. A written survey was conducted in Hesse in order to learn how the participating GPs evaluate the regional HZV. In Apri 2008, a questionnaire was developed, tested and mailed to 2,815 GPs who were participating in the GP-centered health care contract at that time. All analyses where conducted with SPSS (version 15.0). A total of 686 questionnaires were returned (response rate 24.4%). Altogether, the GPs' feedback ranged from great approval to clear disapproval of the contract. However, 70.0% of the survey's participants evaluated the HZV in general to be positive, 60.1% felt it strengthens their role as a GP. Quality circles on good prescribing and GP-specific education, obligatory parts of the HZV, were evaluated to be especially positive (70.3% and 69.4%, respectively). Positive effects were also seen concerning coordination of care (53.3%) and cooperation with patients (36.3%). Improvements concerning cooperation with specialists and hospitals were reported less often (24.9% and 13.0%, respectively). Workload because of additional administration for the HZV was criticized. In future, special GP-centered health care contracts should focus on improvement of cooperation between GPs and other caregivers. Workload for additional administration should be reduced.

Motorized Recreation Sounds Influence Nature Scene Evaluations: The Role of Attitude Moderators

Science.gov (United States)

Benfield, Jacob; Taff, B. D.; Weinzimmer, David; Newman, Peter

2018-01-01

Soundscape assessment takes many forms, including letting the consequences of the soundscape be an indicator of soundscape quality or value. As a result, much social science research has been conducted to better quantify problem soundscapes and the subsequent effects on humans exposed to them. Visual evaluations of natural environments are one area where research has consistently shown detrimental effects of noisy or anthropogenic soundscapes (e.g., those containing noise from motorized recreation), but the potential moderating role of individual attitudes toward elements within the soundscape has not been sufficiently explored. This study demonstrates that both pro-motorized recreation and pro-motorized recreation management attitudes can alter the effect of motorized recreation noise on scenic evaluations in opposing directions. Pro-recreation attitudes lessen the effect of the soundscape, while pro-management attitudes heighten the negative effect of anthropogenic sounds on scenic evaluation. The implications for other areas of soundscape research, especially with regard to soundscape quality assessment through experienced outcomes, are discussed, including possible strategies for prioritizing known or relevant moderating variables. PMID:29706911

Motorized Recreation Sounds Influence Nature Scene Evaluations: The Role of Attitude Moderators.

Science.gov (United States)

Benfield, Jacob; Taff, B D; Weinzimmer, David; Newman, Peter

2018-01-01

Soundscape assessment takes many forms, including letting the consequences of the soundscape be an indicator of soundscape quality or value. As a result, much social science research has been conducted to better quantify problem soundscapes and the subsequent effects on humans exposed to them. Visual evaluations of natural environments are one area where research has consistently shown detrimental effects of noisy or anthropogenic soundscapes (e.g., those containing noise from motorized recreation), but the potential moderating role of individual attitudes toward elements within the soundscape has not been sufficiently explored. This study demonstrates that both pro-motorized recreation and pro-motorized recreation management attitudes can alter the effect of motorized recreation noise on scenic evaluations in opposing directions. Pro-recreation attitudes lessen the effect of the soundscape, while pro-management attitudes heighten the negative effect of anthropogenic sounds on scenic evaluation. The implications for other areas of soundscape research, especially with regard to soundscape quality assessment through experienced outcomes, are discussed, including possible strategies for prioritizing known or relevant moderating variables.

Motorized Recreation Sounds Influence Nature Scene Evaluations: The Role of Attitude Moderators

Directory of Open Access Journals (Sweden)

Jacob Benfield

2018-04-01

Full Text Available Soundscape assessment takes many forms, including letting the consequences of the soundscape be an indicator of soundscape quality or value. As a result, much social science research has been conducted to better quantify problem soundscapes and the subsequent effects on humans exposed to them. Visual evaluations of natural environments are one area where research has consistently shown detrimental effects of noisy or anthropogenic soundscapes (e.g., those containing noise from motorized recreation, but the potential moderating role of individual attitudes toward elements within the soundscape has not been sufficiently explored. This study demonstrates that both pro-motorized recreation and pro-motorized recreation management attitudes can alter the effect of motorized recreation noise on scenic evaluations in opposing directions. Pro-recreation attitudes lessen the effect of the soundscape, while pro-management attitudes heighten the negative effect of anthropogenic sounds on scenic evaluation. The implications for other areas of soundscape research, especially with regard to soundscape quality assessment through experienced outcomes, are discussed, including possible strategies for prioritizing known or relevant moderating variables.

Future planning - utopia

International Nuclear Information System (INIS)

Boernke, F.

1978-01-01

Our life develops as the anticipation of future. Everything we wish, hope, plan and carry out and think is or should be related to future and will have its effects in future. The certainty may spread that it is a necessary obligation to learn to find out our actual being more clearly to be able to develop a thinking and acting that is directed to future that has also a total of responsability as its essence. We will later atone for the failed outlooks into future or for only moderate or uncompleted starts of planning. For this reason we should consider that future does not come for its own, not without our demands, not without our acting. Only if our reflection and aspiration, thinking and acting is done with moderate and circumspect sense in the right way it will be a good fundamental for the future. (orig.) [de

Sedimentary organic biomarkers suggest detrimental effects of PAHs on estuarine microbial biomass during the 20th century in San Francisco Bay, CA, USA

Science.gov (United States)

Nilsen, Elena B.; Rosenbauer, Robert J.; Fuller, Christopher C.; Jaffe, Bruce E.

2014-01-01

Hydrocarbon contaminants are ubiquitous in urban aquatic ecosystems, and the ability of some microbial strains to degrade certain polycyclic aromatic hydrocarbons (PAHs) is well established. However, detrimental effects of petroleum hydrocarbon contamination on nondegrader microbial populations and photosynthetic organisms have not often been considered. In the current study, fatty acid methyl ester (FAME) biomarkers in the sediment record were used to assess historical impacts of petroleum contamination on microbial and/or algal biomass in South San Francisco Bay, CA, USA. Profiles of saturated, branched, and monounsaturated fatty acids had similar concentrations and patterns downcore. Total PAHs in a sediment core were on average greater than 20× higher above ∼200 cm than below, which corresponds roughly to the year 1900. Isomer ratios were consistent with a predominant petroleum combustion source for PAHs. Several individual PAHs exceeded sediment quality screening values. Negative correlations between petroleum contaminants and microbial and algal biomarkers – along with high trans/cis ratios of unsaturated FA, and principle component analysis of the PAH and fatty acid records – suggest a negative impacts of petroleum contamination, appearing early in the 20th century, on microbial and/or algal ecology at the site.

Non-Detriment Finding Regarding the Export of Queen conch (Lobatus gigas) from St Eustatius (Caribbean Netherlands)

NARCIS (Netherlands)

Graaf, de M.; Meijer zu Schlochteren, M.; Boman, E.

2014-01-01

Queen conch (Lobatus gigas (Strombidae; Gastropoda) is a large, long-lived marine gastropod that is widely distributed throughout the coastal zones of the Wider Caribbean region. Because of concern for its future the species was listed in Appendix II of the Convention on International Trade in

Status and future plan of nuclear data activities in China

Energy Technology Data Exchange (ETDEWEB)

Zhuang Youxiang; Tang Hongqing [Academia Sinica, Beijing, BJ (China). Inst. of Atomic Energy

1997-03-01

The present status and future plan of nuclear data measurement and evaluation in China are presented, including the supplement, improvement on CENDL-2.1 and benchmark test of CENDL-2.1, the progress on nuclear data measurement and CENDL-3. (author)

INEL Geothermal Environmental Program. 1979 annual report

Energy Technology Data Exchange (ETDEWEB)

Thurow, T.L.; Sullivan, J.F.

1980-04-01

The Raft River Geothermal Environmental Program is designed to assess beneficial and detrimental impacts to the ecosystem resulting from the development of moderate temperature geothermal resources in the valley. The results of this research contribute to developing an understanding of Raft River Valley ecology and provide a basis for making management decisions to reduce potential long-term detrimental impacts on the environment. The environmental monitoring and research efforts conducted during the past six years of geothermal development and planned future research are summarized.

Oil price assumptions in macroeconomic forecasts: should we follow future market expectations?

International Nuclear Information System (INIS)

Coimbra, C.; Esteves, P.S.

2004-01-01

In macroeconomic forecasting, in spite of its important role in price and activity developments, oil prices are usually taken as an exogenous variable, for which assumptions have to be made. This paper evaluates the forecasting performance of futures market prices against the other popular technical procedure, the carry-over assumption. The results suggest that there is almost no difference between opting for futures market prices or using the carry-over assumption for short-term forecasting horizons (up to 12 months), while, for longer-term horizons, they favour the use of futures market prices. However, as futures market prices reflect market expectations for world economic activity, futures oil prices should be adjusted whenever market expectations for world economic growth are different to the values underlying the macroeconomic scenarios, in order to fully ensure the internal consistency of those scenarios. (Author)

ANSTO - achievements and future directions

International Nuclear Information System (INIS)

Garnett, H. M.

1997-01-01

In the opening keynote address to the conference, Professor Helen Garnett, Executive Director of ANSTO, outlined the Organisation's main achievements and its future directions. In the ten years which have elapsed since its inception in 1987, ANSTO has evolved into a forward thinking, proactive nuclear science and technology Organisation. Its vision for the future is for nuclear science and technology to be accepted as benefiting all Australians and for ANSTO to be acknowledged as the premier nuclear science and technology organisation within the Asia Pacific Region. At the same time the organisation has continually reviewed and evaluated what it was doing and how it was doing. At the end of its first decade, it has enhanced the productivity from its research and development activities, received a positive evaluation on the impact that the application of this knowledge is having on the minerals and other industrial sectors, and focussed its research and development into a few areas where substantial teams of ANSTO staff, working cooperatively with staff from universities, other national organisations and industry, can have significant impact. ANSTO now has four parallel activities: the conduct of research and development, the provision of expert technical advice, the operation of national nuclear facilities and the commercial marketing of products and services. The recent announcement by Australian Government to replace HIFAR reactor with a leading medium flux reactor facility, will enable ANSTO to develop world class capability in selected areas of neutron science and to became an acknowledged regional centre, particular in cold neutron science

An Approach to Evaluate Comprehensive Plan and Identify Priority Lands for Future Land Use Development to Conserve More Ecological Values

Directory of Open Access Journals (Sweden)

Long Zhou

2018-01-01

Full Text Available Urbanization has significant impacts on the regional environmental quality through altering natural lands, converting them to urban built-up areas. One common strategy applied by urban planners to manage urbanization and preserve natural resources is to make a comprehensive plan and concentrate future land use in certain areas. However, in practice, planners used to make future land use planning mainly based on their subjective interpretations with limited ecological supporting evidence and analysis. Here, we propose a new approach composed of ecological modelling and land use zoning in the spatial matrix to evaluate the comprehensive plan and identify priority lands for sustainable land use planning. We use the city of Corvallis, OR, as the test bed to demonstrate this new approach. The results indicate that the Corvallis Comprehensive Plan 1998–2020 featured with compact development is not performing efficiently in conserving ecological values, and the land use plan featured with mixed-use spreading development generated by the proposed approach meets the city’s land demands for urban growth, and conserves 103% more ecological value of retaining storm water nitrogen, 270% more ecological value of retaining storm water phosphorus and 19% more ecological value in storing carbon in the whole watershed. This study indicates that if planned with scientific analysis and evidence, spreading urban development does not necessarily result in less sustainable urban environment than the compact development recommended in smart growth.

Risk assessment analysis of the future technical unit dedicated to the evaluation and treatment of motor disabilities.

Science.gov (United States)

Grelier, S; Thetio, M; Quentin, V; Achache, V; Sanchez, N; Leroux, V; Durand, E; Pequignot, R

2011-03-01

The National Hospital of Saint Maurice (HNSM) for Physical Medicine and Rehabilitation aims at strengthening its position as a pivot rehabilitation and physical therapy center. The opening in 2011 of a new unit for the evaluation and treatment of motor disabilities meets this objective. This project includes several parts: clinical, financial, architectural, organizational, applied clinical research as well as dealing with medical equipments and information system. This study focuses on the risk assessment of this future technical unit. This study was conducted by a group of professionals working for the hospital. It started with the design of a functional model to better comprehend the system to be analyzed. Risk assessment consists in confronting this functional model to a list of dangers in order to determine the vulnerable areas of the system. Then the team designed some scenarios to identify the causes, securities barriers and consequences in order to rank the risks. The analysis targeted various dangers, e.g. political, strategic, financial, economical, marketing, clinical and operational. The team identified more than 70 risky scenarios. For 75% of them the criticality level was deemed initially tolerable and under control or unacceptable. The implementation of an action plan for reducing the level of risks before opening this technical unit brought the system down to an acceptable level at 66%. A year prior to opening this technical unit for the evaluation and treatment of motor disabilities, conducting this preliminary risk assessment, with its exhaustive and rigorous methodology, enabled the concerned professionals to work together around an action plan for reducing the risks. 2011 Elsevier Masson SAS. All rights reserved.

Usage of performance measurement and evaluation systems : the impact of evaluator characteristics

OpenAIRE

Gelderman, Maarten

1998-01-01

This paper discusses the relation between characteristics of the evaluating manager and the way performance measurement and evaluation information is used. First a discussion is provided about the dependent variable. It is recognized that categorization into archetypes (e.g., evaluative styles) is unsatisfactory. Instead the information content/emphasis dimensions financial-non- financial, quantitative-qualitative, process-outcome, past-future and external-internal, along with the dimension f...

Risk Characterization for Future Training Scenarios at the Massachusetts Military Reservation (MMR)

National Research Council Canada - National Science Library

Zakikhani, Mansour

2004-01-01

This study was conducted to evaluate potential human and ecological health risks associated with emission of pyrotechnic compounds during future training exercises at the Massachusetts Military Reservation...

SEURAT: Safety Evaluation Ultimately Replacing Animal Testing--recommendations for future research in the field of predictive toxicology.

Science.gov (United States)

Daston, George; Knight, Derek J; Schwarz, Michael; Gocht, Tilman; Thomas, Russell S; Mahony, Catherine; Whelan, Maurice

2015-01-01

The development of non-animal methodology to evaluate the potential for a chemical to cause systemic toxicity is one of the grand challenges of modern science. The European research programme SEURAT is active in this field and will conclude its first phase, SEURAT-1, in December 2015. Drawing on the experience gained in SEURAT-1 and appreciating international advancement in both basic and regulatory science, we reflect here on how SEURAT should evolve and propose that further research and development should be directed along two complementary and interconnecting work streams. The first work stream would focus on developing new 'paradigm' approaches for regulatory science. The goal here is the identification of 'critical biological targets' relevant for toxicity and to test their suitability to be used as anchors for predicting toxicity. The second work stream would focus on integration and application of new approach methods for hazard (and risk) assessment within the current regulatory 'paradigm', aiming for acceptance of animal-free testing strategies by regulatory authorities (i.e. translating scientific achievements into regulation). Components for both work streams are discussed and may provide a structure for a future research programme in the field of predictive toxicology.

Evolution of the Converged NGN Service Platforms Towards Future Networks

Directory of Open Access Journals (Sweden)

Eugen Mikóczy

2011-03-01

Full Text Available This article presents a comparison of main characteristics of the Next Generation Networks (NGN and Future Generation Internet (FGI. The aim is to discuss and compare two approaches to Future Networks (FN and services: the evolution of NGN, and the revolutionary approach of a new FGI. We present both frameworks from the services point of view as they are delivered to the end-user, as well as from the architectural point of view. We compare selected properties of both approaches to explain commonalities and differences. Their challenges are similar: managing the quality of experience, mobility, security, scalability and providing openness to applications. Based on this comparison, we evaluate possible areas for future convergence in the approach of the two architectures to the Future Network concept. Our analysis shows that despite their different backgrounds, the internet’s FGI and telco’s NGN are not that different after all. The convergence of the two approaches therefore seems the only logical way forward.

Future strategies on IAEA activities and technical cooperation programmes

International Nuclear Information System (INIS)

Kim, Kyoung Pyo; Hong, Young Don

1998-10-01

This study provides basic background information about the establishment of the IAEA, its mission, major activities, General Conference , and Board of Governors, structure and functions of the Secretariat. The IAEA Mid-term plan, to be implemented in the years 1998 - 2003, includes the enhancement of its functional effectiveness, analysis of the changing developments, adjustment of its priorities, and evaluation of its programmes, are describes in full detail. This plan is divided into 6 major areas ; nuclear power and the fuel cycle, nuclear applications, nuclear, radiation and radwaste safety, verification and security of nuclear material, management of technical cooperation for development, policy making, coordination and support. It is also expected that the IAEA plan provides an opportunity to understand the future directions of IAEA programmes and its operational philosophy, thus greatly contributing to Koreas establishment of its own future directions for expanded cooperation with the IAEA, and urges to device effective domestic strategies. This plan will also contribute to the evaluation of Koreas responsibility as a member of the Board of Governors as well as enhance Koreas role as an Advisory Group Member. It is expected that this study is useful for nuclear-related organizations wishing to establish basic directions for the efficient implementation of IAEA technical cooperation programs in the future. (author). 16 refs., 6 tabs., 16 figs

Using Analysis in Children's Literature to Challenge Future Teachers.

Science.gov (United States)

Roberts, Sherron Killingsworth

Teacher educators need to take the responsibility for providing future teachers with long-term evaluative skills necessary to select good literature. Educators must also take responsibility for modeling the powerful notion that books or literature aid in everyone's personal search for meaning. The process of analyzing literature is helpful in…

Evaluation of Stochastic Rainfall Models in Capturing Climate Variability for Future Drought and Flood Risk Assessment

Science.gov (United States)

Chowdhury, A. F. M. K.; Lockart, N.; Willgoose, G. R.; Kuczera, G. A.; Kiem, A.; Nadeeka, P. M.

2016-12-01

One of the key objectives of stochastic rainfall modelling is to capture the full variability of climate system for future drought and flood risk assessment. However, it is not clear how well these models can capture the future climate variability when they are calibrated to Global/Regional Climate Model data (GCM/RCM) as these datasets are usually available for very short future period/s (e.g. 20 years). This study has assessed the ability of two stochastic daily rainfall models to capture climate variability by calibrating them to a dynamically downscaled RCM dataset in an east Australian catchment for 1990-2010, 2020-2040, and 2060-2080 epochs. The two stochastic models are: (1) a hierarchical Markov Chain (MC) model, which we developed in a previous study and (2) a semi-parametric MC model developed by Mehrotra and Sharma (2007). Our hierarchical model uses stochastic parameters of MC and Gamma distribution, while the semi-parametric model uses a modified MC process with memory of past periods and kernel density estimation. This study has generated multiple realizations of rainfall series by using parameters of each model calibrated to the RCM dataset for each epoch. The generated rainfall series are used to generate synthetic streamflow by using a SimHyd hydrology model. Assessing the synthetic rainfall and streamflow series, this study has found that both stochastic models can incorporate a range of variability in rainfall as well as streamflow generation for both current and future periods. However, the hierarchical model tends to overestimate the multiyear variability of wet spell lengths (therefore, is less likely to simulate long periods of drought and flood), while the semi-parametric model tends to overestimate the mean annual rainfall depths and streamflow volumes (hence, simulated droughts are likely to be less severe). Sensitivity of these limitations of both stochastic models in terms of future drought and flood risk assessment will be discussed.

Geopolitical drivers of future tourist flows

Directory of Open Access Journals (Sweden)

Craig Webster

2015-03-01

Full Text Available Purpose – The purpose of this paper is to investigate the major political and economic changes in the world and the likely impact that these changes will bring to tourism and hospitality industries. Design/methodology/approach – The paper adopts a geopolitical perspective on the dynamics of tourist flows, stipulating that geopolitics has a major impact on the size, structure, and direction of these flows. Findings – The paper identifies six geopolitical drivers of tourist flows in the future, namely: the fall of the American Empire, the rise of the BRIC and the PINE countries, increased global political instability, increased importance of regional supranational organisations, greater control of the individuals on a global scale, and the greater importance and power of corporations than national governments. Originality/value – The paper critically evaluates the geopolitical drivers of tourist flows, their likely future development and the impact they have on tourism.

TRAINING SYSTEM OF FUTURE SPECIALISTS: QUALITY CONTROL

Directory of Open Access Journals (Sweden)

Vladimir A. Romanov

2015-01-01

Full Text Available The aim of the investigation is development of innovative strategy of quality control training of engineers and skilled workers (hereinafter – future specialists in educational professional organizations on the principles of social partnership.Methods. Theoretic: theoretic and methodological analysis, polytheoretic synthesis, modeling. Empirical: research and generalization of the system, process and competence – based approaches experience, experiment, observation, surveys, expert evaluation, SWOT-analysis as a method of strategic planning which is to identify the internal and external factors (socio-cultural of the organization surrounding.Results. The strategy of the development of the process of quality control training in educational professional organizations and a predictive model of the system of quality control training for future engineers and workers have been created on the analysis and synthesis of a quantitative specification of the quality, the obtained experience and success in control training of future specialists in educational professional organizations in recent economic and educational conditions.Scientific novelty. There has been built a predicative model of quality control training of future specialists to meet modern standards and the principles of social partnership; the control algorithm of the learning process, developed in accordance with the standards (international of quality ISO in the implementation of the quality control systems of the process approach (matrix-based responsibility, competence and remit of those responsible for the education process in the educational organization, the «problem» terms and diagnostic tools for assessing the quality of professional training of future specialists. The perspective directions of innovation in the control of the quality of future professionals training have been determined; the parameters of a comprehensive analysis of the state of the system to ensure the

Future Issues and Perspectives in the Evaluation of Social Development.

Science.gov (United States)

Marsden, David; Oakley, Peter

1991-01-01

An instrumental/technocratic approach to evaluation of social development relies on primarily quantitative methods. An interpretive approach resists claims to legitimacy and authority of "experts" and questions existing interpretations. The latter approach is characterized by cultural relativism and subjectivity. (SK)

Water, Water Everywhere but is it Safe to Drink? Some Detrimental Health Effects Associated with Consumption of Groundwater Enriched in Naturally-Occurring Contaminants

Science.gov (United States)

Fuge, R.

2007-05-01

Drinking water represents a major pathway of trace elements into the human body. As such, groundwaters, the chemistry of which reflect water/rock interaction, can be a source of trace elements which will have a marked health effect on humans consuming them. Health problems associated with the consumption of groundwater enriched in various elements and compounds have been recorded for many years. For example, high-arsenic groundwaters used for public water supply were first associated with harmful health effects as early as 1917 in Córdoba Province in Argentina, where the local population suffered from skin disorders. Subsequently, in the 1960s consumption of high-arsenic groundwaters was identified as a factor in the aetiology of "black foot disease", an endemic vascular disease, in Taiwan. However, it is problems associated with the very high-arsenic groundwaters of the highly populous Ganges delta area of Bangladesh and West Bengal that has more recently highlighted the health problem of consuming high-arsenic waters. The most obvious problems of excess arsenic consumption through drinking water are arsenical skin lesions, the severity of which being generally correlated with arsenic content of the water. A high incidence of cancers of the skin, bladder and other organs has been recorded in the high-arsenic drinking water areas of the world. A high incidence of vascular disease, found in the arsenic-rich area of Taiwan, has also been shown to occur in Bangladesh. In addition, it has been suggested that high arsenic in drinking water results in increased incidence of diabetes mellitus. Fluorine is another element long recognised as having a major effect on the well-being of humans. Consumption of high-fluorine waters were first identified as having a detrimental effect on teeth in the 1920s and 30s. It was subsequently shown that where fluorine is present in drinking waters at concentrations of around 0.5 to 1 mg/L it can have beneficial effects on humans

Increasing Army Retention Through Incentives

National Research Council Canada - National Science Library

Beerman, Kevin

2006-01-01

.... If the Army fails to address the enlisted retention issue in the near future departures of experienced NCOs will have a detrimental impact our military's ability to provide for our nation's security...

Shanghai Futures Exchange Published Draft of Tin and Nickel Futures Contract

Institute of Scientific and Technical Information of China (English)

2015-01-01

Shanghai Futures Exchange published draft for soliciting opinions for tin and nickel futures contract on its official website on January 19,which implies the marketing time of the long awaited tin and nickel futures is drawing near.According to the draft for soliciting opinions,the transaction unit of tin futures contract is 1tonne/lot,minimum variation unit is 10 yuan/tonne,daily maximum price fluctuation shall

Future-Oriented LCA

DEFF Research Database (Denmark)

Olsen, Stig Irving; Borup, Mads; Andersen, Per Dannemand

2018-01-01

LCA is often applied for decision-making that concerns actions reaching near or far into the future. However, traditional life cycle assessment methodology must be adjusted for the prospective and change-oriented purposes, but no standardised way of doing this has emerged yet. In this chapter some...... challenges are described and some learnings are derived. Many of the future-oriented LCAs published so far perform relatively short-term prediction of simple comparisons. But for more long-term time horizons foresight methods can be of help. Scenarios established by qualified experts about future...... technological and economic developments are indispensable in future technology assessments. The uncertainties in future-oriented LCAs are to a large extent qualitative and it is important to emphasise that LCA of future technologies will provide a set of answers and not ‘the’ answer....

Modelling electricity futures prices using seasonal path-dependent volatility

International Nuclear Information System (INIS)

Fanelli, Viviana; Maddalena, Lucia; Musti, Silvana

2016-01-01

Highlights: • A no-arbitrage term structure model is applied to the electricity market. • Volatility parameters of the HJM model are estimated by using German data. • The model captures the seasonal price behaviour. • Electricity futures prices are forecasted. • Call options are evaluated according to different strike prices. - Abstract: The liberalization of electricity markets gave rise to new patterns of futures prices and the need of models that could efficiently describe price dynamics grew exponentially, in order to improve decision making for all of the agents involved in energy issues. Although there are papers focused on modelling electricity as a flow commodity by using Heath et al. (1992) approach in order to price futures contracts, the literature is scarce on attempts to consider a seasonal volatility as input to models. In this paper, we propose a futures price model that allows looking into observed stylized facts in the electricity market, in particular stochastic price variability, and periodic behavior. We consider a seasonal path-dependent volatility for futures returns that are modelled in Heath et al. (1992) framework and we obtain the dynamics of futures prices. We use these series to price the underlying asset of a call option in a risk management perspective. We test the model on the German electricity market, and we find that it is accurate in futures and option value estimates. In addition, the obtained results and the proposed methodology can be useful as a starting point for risk management or portfolio optimization under uncertainty in the current context of energy markets.

Water availability, water quality water governance: the future ahead

Science.gov (United States)

Tundisi, J. G.; Matsumura-Tundisi, T.; Ciminelli, V. S.; Barbosa, F. A.

2015-04-01

The major challenge for achieving a sustainable future for water resources and water security is the integration of water availability, water quality and water governance. Water is unevenly distributed on Planet Earth and these disparities are cause of several economic, ecological and social differences in the societies of many countries and regions. As a consequence of human misuse, growth of urbanization and soil degradation, water quality is deteriorating continuously. Key components for the maintenance of water quantity and water quality are the vegetation cover of watersheds, reduction of the demand and new water governance that includes integrated management, predictive evaluation of impacts, and ecosystem services. Future research needs are discussed.

The crisis in public health care and academic medicine - proposal ...

African Journals Online (AJOL)

adverse effects of this approach may not be visible in the short term, but the detrimental effect on the education and training of undergraduates and postgraduates, and the future development of medical specialties, will be felt by future generations. Furthermore, the net effect of this is that the most industrious members of staff ...

Future Directions in the Study of Close Relationships: Conflict Is Bad (Except when It's Not)

Science.gov (United States)

Laursen, Brett; Hafen, Christopher A.

2010-01-01

Beneficial and detrimental correlates of interpersonal disagreement have been postulated and documented. The conclusion: conflict is both bad and good. The evidence for these paradoxical effects is summarized. In this article, we argue that the consequences of conflict for individuals depend on its frequency, the way in which it is managed, and…

[What medical students want - evaluation of medical recruitment ads by future physicians].

Science.gov (United States)

Renkawitz, T; Schuster, T; Benditz, A; Craiovan, B; Grifka, J; Lechler, P

2013-10-01

Three-quarters of all hospitals in Germany are now struggling to fill open positions for doctors. The medical job ad is a vital tool for human resources marketing and an important image factor. The present study examines the importance of information and offers in medical recruitment ads on application decisions by medical students. A total of 184 future physicians from clinical semesters participated voluntarily in an anonymous cross-sectional survey. Using a standardised questionnaire, the importance of 49 -individual items extracted from medical recruitment ads were rated with the help of a 4-point Likert Scale. Finally, the study participants prioritised their reasons for an application as a physician. Primary influence on the application decision on medical recruitment ads by medical students had offers/information in relation to education and training aspects and work-life balance. Payment rates for physicians and work load played an important role for the application motivation. Additional earnings for, e. g., emergency calls, providing of medical expertise and assistance with housing, relocation and reimbursement of interview expenses were less crucial. In prioritising key reasons for selecting a prospective employer "regular working hours," an "individual training concept" and an "attractive work-life balance" scored the highest priority. The "opportunity for scientific work" was assigned only a small significance. High importance for the application decision by future physicians on medical recruitment ads is placed on jobs with an opportunity for personal development and aspects that contribute to work-life balance. © Georg Thieme Verlag KG Stuttgart · New York.

Performance Evaluation of Public Key Based Authentication in Future Mobile Communication Systems

Directory of Open Access Journals (Sweden)

Kambourakis Georgios

2004-01-01

Full Text Available While mobile hosts are evolving into full-IP enabled devices, there is a greater demand to provide a more flexible, reconfigurable, and scalable security mechanism in mobile communication systems beyond 3G (B3G. Work has already begun on such an “all-IP” end-to-end solution, commonly referred to as 4G systems. Fully fledged integration between heterogeneous networks, such as 2.5G, UMTS, WLAN, Bluetooth, and the Internet, demands fully compatible, time-tested, and reliable mechanisms to depend on. SSL protocol has proved its effectiveness in the wired Internet and it will probably be the most promising candidate for future wireless environments. In this paper, we discuss existing problems related to authentication and key agreement (AKA procedures, such as compromised authentication vectors attacks, as they appear in current 2/2.5G/3G mobile communication systems, and propose how SSL, combined with public key infrastructure (PKI elements, can be used to overcome these vulnerabilities. In this B3G environment, we perceive authentication as a service, which has to be performed at the higher protocol layers irrespective of the underlying network technology. Furthermore, we analyze the effectiveness of such a solution, based on measurements of a “prototype” implementation. Performance measurements indicate that SSL-based authentication can be possible in terms of service time in future wireless systems, while it can simultaneously provide both the necessary flexibility to network operators and a high level of confidence to end users.

Renewable Electricity Futures Study. Volume 1. Exploration of High-Penetration Renewable Electricity Futures

Energy Technology Data Exchange (ETDEWEB)

Hand, M. M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Baldwin, S. [U.S. Dept. of Energy, Washington, DC (United States); DeMeo, E. [Renewable Energy Consulting, Chicago, IL (United States); Reilly, J. M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Mai, T. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Arent, D. [Joint Inst. for Strategic Energy Analysis, Boulder, CO (United States); Porro, G. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Meshek, M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sandor, D. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2012-06-15

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a future through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%–90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT). Learn more at the RE Futures website. http://www.nrel.gov/analysis/re_futures/

SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons.

Science.gov (United States)

Romeo-Guitart, David; Leiva-Rodríguez, Tatiana; Espinosa-Alcantud, María; Sima, Núria; Vaquero, Alejandro; Domínguez-Martín, Helena; Ruano, Diego; Casas, Caty

2018-05-10

Sirtuin 1 (SIRT1) activity is neuroprotective, and we have recently demonstrated its role in the retrograde degenerative process in motoneurons (MNs) in the spinal cord of rats after peripheral nerve root avulsion (RA) injury. SIRT2 has been suggested to exert effects opposite those of SIRT1; however, its roles in neurodegeneration and neuron response after nerve injury remain unclear. Here we compared the neuroprotective potentials of SIRT1 activation and SIRT2 inhibition in a mouse model of hypoglossal nerve axotomy. This injury induced a reduction of around half MN population within the hypoglossal nucleus by a non-apoptotic neurodegenerative process triggered by endoplasmic reticulum (ER) stress that resulted in activation of the unfolded protein response mediated by IRE1α and XBP1 by 21 days post injury. Both SIRT1 activation with NeuroHeal and SIRT2 inhibition with AK7 protected NSC-34 motor neuron-like cells against ER stress in vitro. In agreement with the in vitro results, NeuroHeal treatment or SIRT1 overexpression was neuroprotective of axotomized hypoglossal MNs in a transgenic mouse model. In contrast, AK7 treatment or SIRT2 genetic depletion in mice inhibited damaged MN survival. To resolve the in vitro/in vivo discrepancies, we used an organotypic spinal cord culture system that preserves glial cells. In this system, AK7 treatment of ER-stressed organotypic cultures was detrimental for MNs and increased microglial nuclear factor-κB and the consequent transcription of cytotoxic pro-inflammatory factors similarly. The results highlight the importance of glial cells in determining the neuroprotective impact of any treatment.

Money market futures

OpenAIRE

Anatoli Kuprianov

1992-01-01

Virtually all financial innovation in the U.S. money market during the past 20 years has centered on interest rate derivatives, including futures and swaps. Furthermore, money market futures--especially futures contracts on Eurodollar time deposits--have been at the vanguard of the recent explosion of trading activity in interest rate derivatives. While futures markets traditionally have been viewed as markets for the transfer of price risk, recent research shows that they may serve other imp...

The Future of the Retail Advertising: Implications for the Finnish Newspaper Industry

OpenAIRE

FLINK, SOILE-MARI

2011-01-01

Starting point for this research was the future changes Internet will cause to Finnish newspaper economies. When evaluating the economic importance of future development to newspapers? economies, one of the most important areas is retail advertising and its shifting to online environment. So far Finnish retail advertising has been very much focused on printed newspapers and retailers? online investments have been moderate and conservative. The change is about to happen and this research answe...

Status of the CSISRS Database for Present and Future Evaluations Work

International Nuclear Information System (INIS)

Rochman, D.

2006-01-01

Full text of publication follows: EXFOR (also called CSISRS for 'Cross-Section Information Storage and Retrieval System') is the database of experimental nuclear reaction data. Published data from all over the world are compiled by the international network of Nuclear Reaction Data Centers. Up to today, about 15500 articles on neutron-, charge particles- and gamma-induced reactions are compiled since 1965, with a short information list and the tabulated experimental data. The database is worldwide used with more than 150 users/day. CSISRS is also included in computational tools, such as the EMPIRE or TALYS nuclear reaction codes, where it becomes a library for experiment-calculation comparisons. In the future, CSISRS compilations may take into account the new search capability and artificial intelligent system such as Google. (author)

Future accelerators (?)

Energy Technology Data Exchange (ETDEWEB)

John Womersley

2003-08-21

I describe the future accelerator facilities that are currently foreseen for electroweak scale physics, neutrino physics, and nuclear structure. I will explore the physics justification for these machines, and suggest how the case for future accelerators can be made.

Fear of Failure and Entrepreneurship: A review and direction for future research

OpenAIRE

Gabriella Cacciotti; James C. Hayton

2014-01-01

The impact of the experience of fear of failure on individual cognition and behaviour can be beneficial as well as detrimental. Despite this dualistic nature, in research on entrepreneurship, fear of failure is examined as only a barrier to entrepreneurial behaviour. A systematic review of the entrepreneurship literature on fear of failure published between 1994 and 2013 reveals a general lack of precision in the conceptualisation and operationalisation of this construct. Drawing on achieveme...

Evaluation of Electrochemical Treatment of Chloride Contaminated Mortar Containing GGBS

Directory of Open Access Journals (Sweden)

Ki Hong Lee

2017-01-01

Full Text Available The present study concerns the influence of cementitious binder on electrochemical treatment of steel embedded in salt contaminated mortar. As binder, ordinary Portland cement (OPC and ground granulated blast furnace slag (GGBS were used and the current density of 250–750 mA/m2 was applied for 4 weeks to complete electrochemical chloride extraction. To evaluate the effect of electrochemical treatment the chloride profile and corrosion behaviour covering chloride concentration, galvanic current density, linear polarization resistance, open circuit potential, and mass loss were measured. An increase in the applied direct current density resulted in a decrease in the chloride concentration at the vicinity of steel, accompanying the mitigated corrosion damage. The performance of electrochemical treatment was more remarkable in mortar containing GGBS presumably due to binding mechanism. However, corrosion damage was more detrimental in GGBS rather than OPC at a given potential, while GGBS had superior corrosion resistance to a corrosive environment and treatment conditions. Therefore, the electrochemical treatment should be conducted prudently to evaluate the corrosion state of embedded steel depending on binder type.

Potential economic benefits of adapting agricultural production systems to future climate change

Science.gov (United States)

Fagre, Daniel B.; Pederson, Gregory; Bengtson, Lindsey E.; Prato, Tony; Qui, Zeyuan; Williams, Jimmie R.

2010-01-01

Potential economic impacts of future climate change on crop enterprise net returns and annual net farm income (NFI) are evaluated for small and large representative farms in Flathead Valley in Northwest Montana. Crop enterprise net returns and NFI in an historical climate period (1960–2005) and future climate period (2006–2050) are compared when agricultural production systems (APSs) are adapted to future climate change. Climate conditions in the future climate period are based on the A1B, B1, and A2 CO2 emission scenarios from the Intergovernmental Panel on Climate Change Fourth Assessment Report. Steps in the evaluation include: (1) specifying crop enterprises and APSs (i.e., combinations of crop enterprises) in consultation with locals producers; (2) simulating crop yields for two soils, crop prices, crop enterprises costs, and NFIs for APSs; (3) determining the dominant APS in the historical and future climate periods in terms of NFI; and (4) determining whether NFI for the dominant APS in the historical climate period is superior to NFI for the dominant APS in the future climate period. Crop yields are simulated using the Environmental/Policy Integrated Climate (EPIC) model and dominance comparisons for NFI are based on the stochastic efficiency with respect to a function (SERF) criterion. Probability distributions that best fit the EPIC-simulated crop yields are used to simulate 100 values for crop yields for the two soils in the historical and future climate periods. Best-fitting probability distributions for historical inflation-adjusted crop prices and specified triangular probability distributions for crop enterprise costs are used to simulate 100 values for crop prices and crop enterprise costs. Averaged over all crop enterprises, farm sizes, and soil types, simulated net return per ha averaged over all crop enterprises decreased 24% and simulated mean NFI for APSs decreased 57% between the historical and future climate periods. Although adapting

Potential Economic Benefits of Adapting Agricultural Production Systems to Future Climate Change

Science.gov (United States)

Prato, Tony; Zeyuan, Qiu; Pederson, Gregory; Fagre, Dan; Bengtson, Lindsey E.; Williams, Jimmy R.

2010-03-01

Potential economic impacts of future climate change on crop enterprise net returns and annual net farm income (NFI) are evaluated for small and large representative farms in Flathead Valley in Northwest Montana. Crop enterprise net returns and NFI in an historical climate period (1960-2005) and future climate period (2006-2050) are compared when agricultural production systems (APSs) are adapted to future climate change. Climate conditions in the future climate period are based on the A1B, B1, and A2 CO2 emission scenarios from the Intergovernmental Panel on Climate Change Fourth Assessment Report. Steps in the evaluation include: (1) specifying crop enterprises and APSs (i.e., combinations of crop enterprises) in consultation with locals producers; (2) simulating crop yields for two soils, crop prices, crop enterprises costs, and NFIs for APSs; (3) determining the dominant APS in the historical and future climate periods in terms of NFI; and (4) determining whether NFI for the dominant APS in the historical climate period is superior to NFI for the dominant APS in the future climate period. Crop yields are simulated using the Environmental/Policy Integrated Climate (EPIC) model and dominance comparisons for NFI are based on the stochastic efficiency with respect to a function (SERF) criterion. Probability distributions that best fit the EPIC-simulated crop yields are used to simulate 100 values for crop yields for the two soils in the historical and future climate periods. Best-fitting probability distributions for historical inflation-adjusted crop prices and specified triangular probability distributions for crop enterprise costs are used to simulate 100 values for crop prices and crop enterprise costs. Averaged over all crop enterprises, farm sizes, and soil types, simulated net return per ha averaged over all crop enterprises decreased 24% and simulated mean NFI for APSs decreased 57% between the historical and future climate periods. Although adapting APSs to

Potential economic benefits of adapting agricultural production systems to future climate change.

Science.gov (United States)

Prato, Tony; Zeyuan, Qiu; Pederson, Gregory; Fagre, Dan; Bengtson, Lindsey E; Williams, Jimmy R

2010-03-01

Potential economic impacts of future climate change on crop enterprise net returns and annual net farm income (NFI) are evaluated for small and large representative farms in Flathead Valley in Northwest Montana. Crop enterprise net returns and NFI in an historical climate period (1960-2005) and future climate period (2006-2050) are compared when agricultural production systems (APSs) are adapted to future climate change. Climate conditions in the future climate period are based on the A1B, B1, and A2 CO(2) emission scenarios from the Intergovernmental Panel on Climate Change Fourth Assessment Report. Steps in the evaluation include: (1) specifying crop enterprises and APSs (i.e., combinations of crop enterprises) in consultation with locals producers; (2) simulating crop yields for two soils, crop prices, crop enterprises costs, and NFIs for APSs; (3) determining the dominant APS in the historical and future climate periods in terms of NFI; and (4) determining whether NFI for the dominant APS in the historical climate period is superior to NFI for the dominant APS in the future climate period. Crop yields are simulated using the Environmental/Policy Integrated Climate (EPIC) model and dominance comparisons for NFI are based on the stochastic efficiency with respect to a function (SERF) criterion. Probability distributions that best fit the EPIC-simulated crop yields are used to simulate 100 values for crop yields for the two soils in the historical and future climate periods. Best-fitting probability distributions for historical inflation-adjusted crop prices and specified triangular probability distributions for crop enterprise costs are used to simulate 100 values for crop prices and crop enterprise costs. Averaged over all crop enterprises, farm sizes, and soil types, simulated net return per ha averaged over all crop enterprises decreased 24% and simulated mean NFI for APSs decreased 57% between the historical and future climate periods. Although adapting APSs

Observing patchy reionization with future CMB polarization experiments

Science.gov (United States)

Roy, A.; Lapi, A.; Spergel, D.; Baccigalupi, C.

2018-05-01

We study the signal from patchy reionization in view of the future high accuracy polarization measurements of the Cosmic Microwave Background (CMB). We implement an extraction procedure of the patchy reionization signal analogous to CMB lensing. We evaluate the signal to noise ratio (SNR) for the future Stage IV (S4) CMB experiment. The signal has a broad peak centered on the degree angular scales, with a long tail at higher multipoles. The CMB S4 experiment can effectively constrain the properties of reionization by measuring the signal on degree scales. The signal amplitude depends on the properties of the structure determining the reionization morphology. We describe bubbles having radii distributed log-normally. The expected S/N is sensitive to the mean bubble radius: bar R=5 Mpc implies S/N ≈ 4, bar R=10 Mpc implies S/N ≈ 20. The spread of the radii distribution strongly affects the integrated SNR, that changes by a factor of 102 when σlnr goes from ln 2 to ln 3. Future CMB experiments will thus place important constraints on the physics of reionization.

Norwegian gas sale in an international perspective - future-directed organization

International Nuclear Information System (INIS)

Saga, B.P.

1996-01-01

This paper deals with future organization of the Norwegian gas sale. The author gives at first a brief review of the Norwegian gas sale, and then a discussion on which type of criteria being based on by evaluation of models for the Norwegian gas sale. A comparison on which type of criteria used in other gas supplying countries is discussed. The author discusses tendencies of development in the international market including Europe, and is questioning if the existing system of gas sale is prepared to meet future challenges. Several types of proposals are presented to solve these challenges. 5 figs

A Prospective Longitudinal Clinical Trial Evaluating Quality of Life After Breast-Conserving Surgery and High-Dose-Rate Interstitial Brachytherapy for Early-Stage Breast Cancer

Energy Technology Data Exchange (ETDEWEB)

Garsa, Adam A.; Ferraro, Daniel J.; DeWees, Todd A. [Department of Radiation Oncology, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Deshields, Teresa L. [Department of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Margenthaler, Julie A.; Cyr, Amy E. [Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Naughton, Michael [Department of Medicine, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Aft, Rebecca [Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Department of Surgery, John Cochran Veterans Hospital, St. Louis, Missouri (United States); Gillanders, William E.; Eberlein, Timothy [Department of Surgery, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Matesa, Melissa A.; Ochoa, Laura L. [Department of Radiation Oncology, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States); Zoberi, Imran, E-mail: izoberi@radonc.wustl.edu [Department of Radiation Oncology, Siteman Cancer Center, Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, Missouri (United States)

2013-12-01

Purpose: To prospectively examine quality of life (QOL) of patients with early stage breast cancer treated with accelerated partial breast irradiation (APBI) using high-dose-rate (HDR) interstitial brachytherapy. Methods and Materials: Between March 2004 and December 2008, 151 patients with early stage breast cancer were enrolled in a phase 2 prospective clinical trial. Eligible patients included those with Tis-T2 tumors measuring ≤3 cm excised with negative surgical margins and with no nodal involvement. Patients received 3.4 Gy twice daily to a total dose of 34 Gy. QOL was measured using European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, version 3.0, and QLQ-BR23 questionnaires. The QLQ-C30 and QLQ-BR23 questionnaires were evaluated during pretreatment and then at 6 to 8 weeks, 3 to 4 months, 6 to 8 months, and 1 and 2 years after treatment. Results: The median follow-up was 55 months. Breast symptom scores remained stable in the months after treatment, and they significantly improved 6 to 8 months after treatment. Scores for emotional functioning, social functioning, and future perspective showed significant improvement 2 years after treatment. Symptomatic fat necrosis was associated with several changes in QOL, including increased pain, breast symptoms, systemic treatment side effects, dyspnea, and fatigue, as well as decreased role functioning, emotional functioning, and social functioning. Conclusions: HDR multicatheter interstitial brachytherapy was well tolerated, with no significant detrimental effect on measured QOL scales/items through 2 years of follow-up. Compared to pretreatment scores, there was improvement in breast symptoms, emotional functioning, social functioning, and future perspective 2 years after treatment.

A Prospective Longitudinal Clinical Trial Evaluating Quality of Life After Breast-Conserving Surgery and High-Dose-Rate Interstitial Brachytherapy for Early-Stage Breast Cancer

International Nuclear Information System (INIS)

Garsa, Adam A.; Ferraro, Daniel J.; DeWees, Todd A.; Deshields, Teresa L.; Margenthaler, Julie A.; Cyr, Amy E.; Naughton, Michael; Aft, Rebecca; Gillanders, William E.; Eberlein, Timothy; Matesa, Melissa A.; Ochoa, Laura L.; Zoberi, Imran

2013-01-01

Purpose: To prospectively examine quality of life (QOL) of patients with early stage breast cancer treated with accelerated partial breast irradiation (APBI) using high-dose-rate (HDR) interstitial brachytherapy. Methods and Materials: Between March 2004 and December 2008, 151 patients with early stage breast cancer were enrolled in a phase 2 prospective clinical trial. Eligible patients included those with Tis-T2 tumors measuring ≤3 cm excised with negative surgical margins and with no nodal involvement. Patients received 3.4 Gy twice daily to a total dose of 34 Gy. QOL was measured using European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30, version 3.0, and QLQ-BR23 questionnaires. The QLQ-C30 and QLQ-BR23 questionnaires were evaluated during pretreatment and then at 6 to 8 weeks, 3 to 4 months, 6 to 8 months, and 1 and 2 years after treatment. Results: The median follow-up was 55 months. Breast symptom scores remained stable in the months after treatment, and they significantly improved 6 to 8 months after treatment. Scores for emotional functioning, social functioning, and future perspective showed significant improvement 2 years after treatment. Symptomatic fat necrosis was associated with several changes in QOL, including increased pain, breast symptoms, systemic treatment side effects, dyspnea, and fatigue, as well as decreased role functioning, emotional functioning, and social functioning. Conclusions: HDR multicatheter interstitial brachytherapy was well tolerated, with no significant detrimental effect on measured QOL scales/items through 2 years of follow-up. Compared to pretreatment scores, there was improvement in breast symptoms, emotional functioning, social functioning, and future perspective 2 years after treatment

Renewable Electricity Futures Study. Volume 1: Exploration of High-Penetration Renewable Electricity Futures

Energy Technology Data Exchange (ETDEWEB)

Mai, T.; Wiser, R.; Sandor, D.; Brinkman, G.; Heath, G.; Denholm, P.; Hostick, D.J.; Darghouth, N.; Schlosser, A.; Strzepek, K.

2012-06-01

The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a future through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).

Information evaluation

CERN Document Server

Capet, Philippe

2014-01-01

During the reception of a piece of information, we are never passive. Depending on its origin and content, from our personal beliefs and convictions, we bestow upon this piece of information, spontaneously or after reflection, a certain amount of confidence. Too much confidence shows a degree of naivety, whereas an absolute lack of it condemns us as being paranoid. These two attitudes are symmetrically detrimental, not only to the proper perception of this information but also to its use. Beyond these two extremes, each person generally adopts an intermediate position when faced with the recep

Evaluation of potential interactions between forest biomass production and Canadian wildlife. Final report

Energy Technology Data Exchange (ETDEWEB)

Coulombe, R.; Lemay, A.B.

1983-06-01

Forest management for biomass production can be undertaken in all provinces of Canada. Raw material can be extracted either from sawmills, logged areas, silvicultural treatments or short-rotation intensive culture. All forests are suitable habitats for wildlife. However, some species (e.g. woodland caribou, lynx, marten, owl) are extremely dependant on mature forests. Logging these forests generally contributes to reduction of habitats and thus populations. Management of second growth forests should take into consideration these species by extending rotations so part of the forests will serve the species. Removal of snags and downed logs to increase amount of raw material will contribute to reduced habitats of, for instance, tree-nesting birds. As these aspects have not been intensively studied within the Canadian forest regions, interactions can hardly be specified. Studies are recommended to analyse the overall problems and define measures to prevent detrimental effects. Other species (rare, threatened or endangered) will need specific attention and precaution while managing forests. Some are highly sensitive to noise and human disturbance (e.g. whooping crane, white pelican, peregrine falcon), others are very sensitive to harassment. Increased human presence within managed forests will necessitate more educational programs to prevent detrimental effects. Some species of reptiles, amphibians and fish are so poorly documented that only basic studies of the biology, ecology and distribution will permit to identify and evaluate interactions with these new forestry concepts. 289 refs., 19 figs., 36 tabs.

The future challenges for HIA

International Nuclear Information System (INIS)

Kemm, John

2005-01-01

Health Impact Assessment has made impressive progress over the past 10 years achieving greater clarity over the nature of HIA, understanding that different methods were appropriate for different contexts and accepting that a variety of types of evidence were needed. However areas remain where further progress is needed. Much progress has been made on how HIA informs decision makers but HIA practitioners still need greater understanding of decision making processes and how HIA should relate to them. Predicting the future consequences of following different options is a key element of HIA but there is still need for more robust methods of prediction and in particular better prediction of the magnitude of impacts. Few HIA reports adequately describe the distribution of impacts between different groups and this is another area where improvement is needed. Considerable progress has been made in clarifying the role of participation in HIA but the practice has often been less impressive than the rhetoric. HIA practitioners also need to become more critical in evaluating their activities. In the future it is likely that commercial organisations and EIA practitioners will become more involved in HIA and quality control of HIA practice will become even more important

RF Wireless Power Transfer: Regreening Future Networks

OpenAIRE

Tran, Ha-Vu; Kaddoum, Georges

2017-01-01

Green radio communication is an emerging topic since the overall footprint of information and communication technology (ICT) services is predicted to triple between 2007 and 2020. Given this research line, energy harvesting (EH) and wireless power transfer (WPT) networks can be evaluated as promising approaches. In this paper, an overview of recent trends for future green networks on the platforms of EH and WPT is provided. By rethinking the application of radio frequency (RF)-WPT, a new conc...

Foreword. The Knowledge Economy: The Present Future

OpenAIRE

Constantin Bratianu

2017-01-01

All the statistics and evaluations show that the Knowledge Economy is our future. However, a close look at the developed economies demonstrates that the Knowledge Economy is already here, shaping our present time. Although there are many definitions of this new economic framework, their core content stresses the importance of data, information, and knowledge in the production of goods and delivering services in creating value for society. For instance, Powell and Snellman (2004, p.1999) defin...

Qualitative Description of Electric Power System Future States

Energy Technology Data Exchange (ETDEWEB)

Hardy, Trevor D.; Corbin, Charles D.

2018-03-06

The simulation and evaluation of transactive systems depends to a large extent on the context in which those efforts are performed. Assumptions regarding the composition of the electric power system, the regulatory and policy environment, the distribution of renewable and other distributed energy resources (DERs), technological advances, and consumer engagement all contribute to, and affect, the evaluation of any given transactive system, regardless of its design. It is our position that the assumptions made about the state of the future power grid will determine, to some extent, the systems ultimately deployed, and that the transactive system itself may play an important role in the evolution of the power system.

Evaluation of alternative future energy scenarios for Brazil using an energy mix model

Science.gov (United States)

Coelho, Maysa Joppert

The purpose of this study is to model and assess the performance and the emissions impacts of electric energy technologies in Brazil, based on selected economic scenarios, for a time frame of 40 years, taking the year of 1995 as a base year. A Base scenario has been developed, for each of three economic development projections, based upon a sectoral analysis. Data regarding the characteristics of over 300 end-use technologies and 400 energy conversion technologies have been collected. The stand-alone MARKAL technology-based energy-mix model, first developed at Brookhaven National Laboratory, was applied to a base case study and five alternative case studies, for each economic scenario. The alternative case studies are: (1) minimum increase in the thermoelectric contribution to the power production system of 20 percent after 2010; (2) extreme values for crude oil price; (3) minimum increase in the renewable technologies contribution to the power production system of 20 percent after 2010; (4) uncertainty on the cost of future renewable conversion technologies; and (5) model is forced to use the natural gas plants committed to be built in the country. Results such as the distribution of fuel used for power generation, electricity demand across economy sectors, total CO2 emissions from burning fossil fuels for power generation, shadow price (marginal cost) of technologies, and others, are evaluated and compared to the Base scenarios previous established. Among some key findings regarding the Brazilian energy system it may be inferred that: (1) diesel technologies are estimated to be the most cost-effective thermal technology in the country; (2) wind technology is estimated to be the most cost-effective technology to be used when a minimum share of renewables is imposed to the system; and (3) hydroelectric technologies present the highest cost/benefit relation among all conversion technologies considered. These results are subject to the limitations of key input

Towards Narrative Futuring in Psychology: Becoming Resilient by Imagining the Future

NARCIS (Netherlands)

Sools, Anna Maria; Mooren, J.H.M.

2012-01-01

In this article we develop a narrative psychological approach to futuring (imagining the future). We explore how this approach addresses the question of how people can become resilient in order to anticipate (social) crisis and change. Firstly, we bring to the fore how futuring takes shape in

Making the Future Palpable

DEFF Research Database (Denmark)

Büscher, Monika; Kristensen, Margit; Mogensen, Preben Holst

2007-01-01

In this paper we describe experiences from a Future Laboratory. Future laboratories allow users to experiment with prototypes of future technologies in as realistic as possible conditions. We have devised this method because, to realize the potential of advanced ubiquitous computing technologies...... it is essential to anticipate and design for future practices, but for prospective users it is often difficult to imagine and articulate future practices and provide design specifications. They readily invent new ways of working in engagement with new technologies, through and, by facilitating as realistic...... as possible use of prototype future technologies in Future Laboratories designers and users can define and study both opportunities and constraints for design. We present 11 scenes from a Major Incidents Future Laboratory held in September 2005. In relation to each scene we point out key results. Many raise...

Special Issue: Enhancing Sustainable Performance in Organizational and Inter-Institutional Systems

Directory of Open Access Journals (Sweden)

Graham Winch

2013-05-01

Full Text Available Sustainability is not just for Christmas… it’s for life. Sustainable solutions, whether sought in terms of business strategies, social policies, or the exploitation of natural resources have to serve organizations and communities in the long term, sometimes very long term, as well as the short term. Static analysis is unlikely to be able to evaluate candidate solutions fully, and is more likely to focus on the short-term future to the detriment of the longer-term. Sustainable solutions are more likely to be developed from studies based on deep analysis using systems approaches, and from system dynamics (SD approaches in particular.

Substance abuse and psychosocial adaptation to physical disability: analysis of the literature and future directions.

Science.gov (United States)

Smedema, Susan Miller; Ebener, Deborah

2010-01-01

To analyse the current state of the literature with respect to substance abuse and psychosocial adjustment in persons with disabilities. The two primary databases containing the literature related to rehabilitation and disability issues (PsychINFO and MedLine) were searched to identify articles addressing the psychosocial impact of substance abuse in persons with disabilities. Eleven empirical articles specifically measuring the strength of the relationship between substance use and psychosocial outcomes in persons with disabilities were selected for analysis. Of the studies identified, five were related to spinal cord injury, three were related to traumatic brain injury, one was related to chronic back pain, one was related to HIV/AIDS, and one was related to persons with any type of disability. Each of the studies used different methodologies, measured substance abuse in different ways, and examined different psychosocial outcome variables. Examination of trends suggested that pre-injury substance abuse appears to be unrelated to acceptance of disability in persons with spinal cord injury and negatively associated with satisfaction in persons with traumatic brain injury. Recent substance abuse tends to have a detrimental effect on psychosocial outcomes across all disability groups. Future research, combined with appropriate pre-service and continuing education related to substance abuse and disability for rehabilitation practitioners, has the potential to lead to improved psychosocial outcomes in persons with disabilities.

Hydrological scenarios of future seasonal runoff distribution in Central Slovakia

International Nuclear Information System (INIS)

Hlavcova, K; Szolgay, J; Kohnova, S; Balint, G

2008-01-01

The hydrological scenarios of future seasonal distributions of runoff in the upper Hron River basin, which was chosen as a representative mountainous region in Central Slovakia, were evaluated. Changes in the future climate were expressed by three different climate change scenarios developed within the framework of the Central and Eastern Europe Climate Change Impact and Vulnerability Assessment Project (CECILIA). The climate change scenarios were constructed using the pattern scaling method from the outputs of transient simulations made by 3 GCMs - ECHAM4/OPYC3, HadCM2 and NCAR DOE-PCM. A conceptual hydrological balance model calibrated with data from the period 1971-2000 was used for modelling changes in runoff with monthly time steps. The runoff change scenarios for the selected basin in the future time horizons of 2025, 2050 and 2100 show changes in the seasonal runoff distribution.

Customer satisfaction and customer loyalty as predictors of future business potential

DEFF Research Database (Denmark)

Eskildsen, Jacob Kjær; Kristensen, Kai

2008-01-01

This paper analyses the relationship between customer satisfaction, customer loyalty and the future business potential of existing customers. The data for the analysis come from the Danish Customer Satisfaction Index 2006. Here a total of approximately 2000 private customers evaluated...

Anticipating Their Future: Adolescent Values for the Future Predict Adult Behaviors

Science.gov (United States)

Finlay, Andrea K.; Wray-Lake, Laura; Warren, Michael; Maggs, Jennifer

2015-01-01

Adolescent future values--beliefs about what will matter to them in the future--may shape their adult behavior. Utilizing a national longitudinal British sample, this study examined whether adolescent future values in six domains (i.e., family responsibility, full-time job, personal responsibility, autonomy, civic responsibility, and hedonistic…

Greening the Future

Science.gov (United States)

Williamson, Norma Velia

2011-01-01

Because educators vicariously touch the future through their students, the author believes that they sometimes have the uncanny ability to see the future. One common future forecast is the phenomenal growth of green jobs in the emerging green economy, leading to the creation of the "Reach of the Sun" Solar Energy Academy at La Mirada…

Effect of oxygen concentration on human embryo development evaluated by time-lapse monitoring

DEFF Research Database (Denmark)

Ingerslev, Hans Jakob; Hindkjær, Johnny Juhl; Kirkegaard, Kirstine

2012-01-01

-points for each cell division and blastocyst stages were registered until 120 hours after oocyte retrieval. Only 2PN embryos completing the first cleavage were evaluated. The groups were compared using one-way ANOVA or Kruskall-Wallis test. Estimates are reported as medians with 95% confidence intervals. Time......Introduction: Data from a number of studies indicate -but not unequivocally- that culture of embryos in 5% O2 compared to 20% O2 improves blastocyst formation in humans and various animal species and may yield better pregnancy rates in IVF. The detrimental effects of atmospheric oxygen were...... was to evaluate the influence of oxygen tension on human pre-implantation development using time-lapse monitoring. Materials and methods: Human embryos were cultured to the blastocyst stage in a time-lapse incubator (EmbryoScope™) in 20% O2 (group 1), 20% O2 for 24 hours followed by culture in 5% O2 (group 2...

Analysis of the efficiency of the Iberian power futures market

International Nuclear Information System (INIS)

Capitan Herraiz, Alvaro; Rodriguez Monroy, Carlos

2009-01-01

Market efficiency is analysed for the Iberian Power Futures Market and other European Power Markets, as well as other fuel markets through evaluation of ex-post Forward Risk Premium. The equilibrium price from compulsory call auctions for distribution companies within the framework of the Iberian Power Futures Market is not optimal for remuneration purposes as it seems to be slightly upward biased. In the period considered (August 2006-July 2008), monthly futures contracts behave similarly to quarterly contracts. Average risk premia have been positive in power and natural gas markets but negative in oil and coal markets. Different hypotheses are tested regarding increasing volatility with maturity and regarding Forward Risk Premium variations (decreasing with variance of spot prices during delivery period and increasing with skewness of spot prices during delivery period). Enlarged data sets are recommended for stronger test results. Energy markets tend to show limited levels of market efficiency. Regarding the emerging Iberian Power Futures Market, price efficiency is improved with market development of all the coexistent forward contracting mechanisms and with further integration of European Regional Electricity Markets. (author)

Overly positive self-evaluations and personality: negative implications for mental health.

Science.gov (United States)

Colvin, C R; Block, J; Funder, D C

1995-06-01

The relation between overly positive self-evaluations and psychological adjustment was examined. Three studies, two based on longitudinal data and another on laboratory data, contrasted self-descriptions of personality with observer ratings (trained examiners or friends) to index self-enhancement. In the longitudinal studies, self-enhancement was associated with poor social skills and psychological maladjustment 5 years before and 5 years after the assessment of self-enhancement. In the laboratory study, individuals who exhibited a tendency to self-enhance displayed behaviors, independently judged, that seemed detrimental to positive social interaction. These results indicate there are negative short-term and long-term consequences for individuals who self-enhance and, contrary to some prior formulations, imply that accurate appraisals of self and of the social environment may be essential elements of mental health.

ENGINEERING STUDY FOR THE 200 AREA EFFLUENT TREATMENT FACILITY (ETF) SECONDARY WASTE TREATMENT OF PROJECTED FUTURE WASTE FEEDS

International Nuclear Information System (INIS)

LUECK, K.J.

2004-01-01

This report documents an engineering study conducted to evaluate alternatives for treating secondary waste in the secondary treatment train (STT) of the Hanford Site 200 Area Effluent Treatment Facility (ETF). The study evaluates ETF STT treatment alternatives and recommends preferred alternatives for meeting the projected future missions of the ETF. The preferred alternative(s) will process projected future ETF influents to produce a solid waste acceptable for final disposal on the Hanford Site. The main text of this report summarizes the ETF past and projected operations, lists the assumptions about projected operations that provide the basis for the engineering evaluation, and summarizes the evaluation process. The evaluation process includes identification of available modifications to the current ETF process, screens those modifications for technical viability, evaluates the technically viable alternatives, and provides conclusions and recommendations based on that evaluation

Future perspectives

International Nuclear Information System (INIS)

Anon.

1987-01-01

International involvement in particle physics is what the International Committee for Future Accelerators (ICFA) is all about. At the latest Future Perspectives meeting at Brookhaven from 5-10 October (after a keynote speech by doyen Viktor Weisskopf, who regretted the emergence of 'a nationalistic trend'), ICFA reviewed progress and examined its commitments in the light of the evolving world particle physics scene. Particular aims were to review worldwide accelerator achievements and plans, to survey the work of the four panels, and to discuss ICFA's special role in future cooperation in accelerator construction and use, and in research and development work for both accelerators and for detectors

Evaluation of carbon fiber composites fabricated using ionic liquid based epoxies for cryogenic fluid applications

Directory of Open Access Journals (Sweden)

R.N. Grugel

Full Text Available Utilizing tanks fabricated from fiber reinforced polymeric composites for storing cryogenic fluids such as liquid oxygen and liquid hydrogen is of great interest to NASA as considerable weight savings can be gained. Unfortunately such composites, especially at cryogenic temperatures, develop a mismatch that initiates detrimental delamination and crack growth, which promotes leaking. On-going work with ionic liquid-based epoxies appears promising in mitigating these detrimental effects. Some recent results are presented and discussed. Keywords: Ionic liquid, Carbon fiber, Epoxy, COPV, Cryogenic fluids

Future Textiles

DEFF Research Database (Denmark)

Hansen, Anne-Louise Degn; Jensen, Hanne Troels Fusvad; Hansen, Martin

2011-01-01

Magasinet Future Textiles samler resultaterne fra projektet Future Textiles, der markedsfører området intelligente tekstiler. I magasinet kan man læse om trends, drivkræfter, udfordringer samt få ideer til nye produkter inden for intelligente tekstiler. Områder som bæredygtighed og kundetilpasning...

Preschool life skills: Recent advancements and future directions.

Science.gov (United States)

Fahmie, Tara A; Luczynski, Kevin C

2018-01-01

Over the past decade, researchers have replicated and extended research on the preschool life skills (PLS) program developed by Hanley, Heal, Tiger, and Ingvarsson (2007). This review summarizes recent research with respect to maximizing skill acquisition, improving generality, evaluating feasibility and acceptability, and testing predictions of the initial PLS study. For each area, we suggest directions for future research. © 2018 Society for the Experimental Analysis of Behavior.

Environmental Scanning, Futures Research, Strategic Foresight and Organizational Future Orientation

DEFF Research Database (Denmark)

Rohrbeck, René; Bade, Manuel

to adjacent research disciplines. Through such integration and linkage research should produce better recommendations for managers on how to build an organizational future orientation, drive organizational adaptation, and make their firms robust towards external discontinuous change.......In this paper we explore the current understanding on how firms explore future changes and trends as well as plan their managerial responses. We review literature in four research streams: (1) environmental scanning, (2) futures research, (3) peripheral vision, and (4) corporate/strategic foresight....... Through the analysis of more than 250 articles we (a) trace the evolution over time, (b) highlight the linkages between the different research streams, and (c) give recommendations for future research. Overall we call for more cross-fertilization of the different research streams and a stronger linkage...

Limiting Future Proliferation and Security Risks

International Nuclear Information System (INIS)

Bari, R.

2011-01-01

A major new technical tool for evaluation of proliferation and security risks has emerged over the past decade as part the activities of the Generation IV International Forum. The tool has been developed by a consensus group from participating countries and organizations and is termed the Proliferation Resistance and Physical Protection (PR and PP) Evaluation Methodology. The methodology defines a set of challenges, analyzes system response to these challenges, and assesses outcomes. The challenges are the threats posed by potential actors (proliferant states or sub-national adversaries). It is of paramount importance in an evaluation to establish the objectives, capabilities, resources, and strategies of the adversary as well as the design and protection contexts. Technical and institutional characteristics are both used to evaluate the response of the system and to determine its resistance against proliferation threats and robustness against sabotage and terrorism threats. The outcomes of the system response are expressed in terms of a set of measures, which thereby define the PR and PP characteristics of the system. This paper summarizes results of applications of the methodology to nuclear energy systems including reprocessing facilities and large and small modular reactors. The use of the methodology in the design phase a facility will be discussed as it applies to future safeguards concepts.

Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome.

Directory of Open Access Journals (Sweden)

Olivia Hoffman

Full Text Available A hallmark of acute respiratory distress syndrome (ARDS is accumulation of protein-rich edema in the distal airspaces and its removal is critical for patient survival. Previous studies have shown a detrimental role of Glycogen Synthase Kinase (GSK 3β during ARDS via inhibition of alveolar epithelial protein transport. We hypothesized that post-transcriptional regulation of GSK3β could play a functional role in ARDS resolution. To address this hypothesis, we performed an in silico analysis to identify regulatory genes whose expression correlation to GSK3β messenger RNA utilizing two lung cancer cell line array datasets. Among potential regulatory partners of GSK3β, these studies identified the RNA-binding protein ELAVL-1/HuR (Embryonic Lethal, Abnormal Vision, Drosophila-Like as a central component in a likely GSK3β signaling network. ELAVL-1/HuR is a RNA-binding protein that selectively binds to AU-rich elements of mRNA and enhances its stability thereby increasing target gene expression. Subsequent studies with siRNA suppression of ELAVL-1/HuR demonstrated deceased GSK3β mRNA and protein expression and improved clearance of FITC-albumin in A549 cells. Conversely, stabilization of ELAVL-1/HuR with the proteasome inhibitor MG-132 resulted in induction of GSK3β at mRNA and protein level and attenuated FITC-albumin clearance. Utilizing ventilator-induced lung injury or intra-tracheal installation of hydrochloric acid to induce ARDS in mice, we observed increased mRNA and protein expression of ELAVL-1/HuR and GSK3β. Together, our findings indicate a previously unknown interaction between GSK3β and ELAV-1 during ARDS, and suggest the inhibition of the ELAV-1- GSK3β pathways as a novel ARDS treatment approach.

Evaluation of geophysical borehole studies

International Nuclear Information System (INIS)

Brotzen, O.; Duran, O.; Magnusson, K.Aa.

Four studies concerning geophysical investigations and TV inspection in boreholes in connection with KBS studies at Finnsjoe, Karlshamn, Kraakemaala and Stripa and PRAV's studies at Studsvik have been evaluated. This has led to proposals concerning the choice of instruments and methods for future studies and a review of future work required. The evaluation has shown that the following borehole measurements are of primary interest in the continued work: Determinations of temperature and resistivity of the borehole liquid, resistance and resistivity measurements, SP, Sonic, Caliper and VLF. TV inspection, IP and gamma-gamma should also be included in the arsenal of available test methods.(author)

Evaluating Labour's market reforms, 2002-10.

Science.gov (United States)

Mays, Nicholas; Tan, Stefanie

2012-01-01

Starting in 2002, the UK Labour government of 1997-2010 introduced a series of changes to the National Health Service (NHS) in England designed to increase individual NHS patient choice of place of elective hospital care and competition among public and private providers of elective hospital services for NHS-funded patients. In 2006, the Department of Health initiated the Health Reform Evaluation Programme (HREP) to assess the impact of the changes. The changes broadly had the effects that proponents had predicted but the effects were mostly modest. Most of the undesirable impacts feared by critics appeared not to have materialized to any discernible extent, at least by early in 2010. Labour's market appeared to have generated stronger incentives for quality and efficiency than its 1990 s predecessor with no obvious detriment to equity of access. However, this high level conclusion conceals a far more nuanced and complex picture of both the process of implementation and the impact of the changes, as the papers in this supplement drawn from the HREP show.

Teen camp: a unique approach to recruit future nurses.

Science.gov (United States)

Redding, Donna A; Riech, Sandy; Prater, Marsha A

2004-01-01

A collaborative and unique approach to interest high school students in nursing. To inform educators and nursing departments about an innovative approach to recruit future nurses. Professional literature and authors' experience. All students related positive experiences. The initial camp evaluation produced innovative input from the students, and each camp met its goal of creating career interest in the nursing profession.

Current status and future directions for in situ transmission electron microscopy

Energy Technology Data Exchange (ETDEWEB)

Taheri, Mitra L. [Department of Materials Science and Engineering, Drexel University (United States); Stach, Eric A. [Center for Functional Nanomaterials, National Laboratory, Brookhaven (United States); Arslan, Ilke [Pacific Northwest National Laboratory, Physical and Computational Sciences Directorate, 902 Battelle Blvd, Richland, WA (United States); Crozier, P.A. [School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ 85281 (United States); Kabius, Bernd C. [The Pennsylvania State University, University Park, PA 16802 (United States); LaGrange, Thomas [Lawrence Livermore National Laboratory, Physical and Life Science Directorate, Condensed Matter and Materials Division, 7000 East Avenue, P.O. 808 L-356 (United States); Minor, Andrew M. [Department of Materials Science & Engineering, University of California, Berkeley and National Center for Electron Microscopy, Molecular Foundry, Lawrence Berkeley National Laboratory, One Cyclotron Road, MS 72, Berkeley, CA (United States); Takeda, Seiji [Institute of Scientific and Industrial Research (ISIR), Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka 567-0047 (Japan); Tanase, Mihaela [Center for Nanoscale Science and Technology, National Institute of Standards and Technology, Gaithersburg, MD 20899-6203 (United States); Wagner, Jakob B. [Center for Electron Nanoscopy, Technical University of Denmark, Kgs, Lyngby (Denmark); Sharma, Renu, E-mail: renu.sharma@nist.gov [Center for Nanoscale Science and Technology, National Institute of Standards and Technology, Gaithersburg, MD 20899-6203 (United States)

2016-11-15

This review article discusses the current and future possibilities for the application of in situ transmission electron microscopy to reveal synthesis pathways and functional mechanisms in complex and nanoscale materials. The findings of a group of scientists, representing academia, government labs and private sector entities (predominantly commercial vendors) during a workshop, held at the Center for Nanoscale Science and Technology- National Institute of Science and Technology (CNST-NIST), are discussed. We provide a comprehensive review of the scientific needs and future instrument and technique developments required to meet them. - Highlights: • Evaluation of currently available technology for performing in situ experiments using transmission electron microscope. • Limitations of currently available instrumentation with respect to base TEM, specialty TEM holders, and data acquisition systems. • Guidelines and wish list for the areas of future development.

Current status and future directions for in situ transmission electron microscopy

International Nuclear Information System (INIS)

Taheri, Mitra L.; Stach, Eric A.; Arslan, Ilke; Crozier, P.A.; Kabius, Bernd C.; LaGrange, Thomas; Minor, Andrew M.; Takeda, Seiji; Tanase, Mihaela; Wagner, Jakob B.; Sharma, Renu

2016-01-01

This review article discusses the current and future possibilities for the application of in situ transmission electron microscopy to reveal synthesis pathways and functional mechanisms in complex and nanoscale materials. The findings of a group of scientists, representing academia, government labs and private sector entities (predominantly commercial vendors) during a workshop, held at the Center for Nanoscale Science and Technology- National Institute of Science and Technology (CNST-NIST), are discussed. We provide a comprehensive review of the scientific needs and future instrument and technique developments required to meet them. - Highlights: • Evaluation of currently available technology for performing in situ experiments using transmission electron microscope. • Limitations of currently available instrumentation with respect to base TEM, specialty TEM holders, and data acquisition systems. • Guidelines and wish list for the areas of future development.

Future prospects for renewable energy sources in a global frame

International Nuclear Information System (INIS)

Lund, P.

1992-06-01

The objective of this study has been to evaluate the possibilities of some new energy sources (solar, wind) in the future world energy supply. We intend to prepare future projections accounting for limitations in infrastructure, time and material inputs. One underlying assumption in the analyses is that new technologies will see an early market introduction in the near future which would continue up to year 2020. During these 30 years, there will still be technological developments leading to a much better manufacturability, mass production, and hence reduced costs. In year 2020, the industrial and economic infrastructure of new energy sources would be mature for a major penetration into the world energy market starting to substitute existing energy sources mainly for environmental reasons. This scenario will be suported by more factual information and data in the following chapters. Each new energy technology will be handled separately. (Quittner)

Negative radiographic examinations: Evaluation of risks from exposure

International Nuclear Information System (INIS)

Frometa Suarez, I.; Jerez Vegueria, S.F.

1997-01-01

The individual dose of radiation per radiological diagnosis is decreasing, which is an important contribution for the number of exposed population. This is a result of a completed study presented by the Manuel Fajardo Surgery Clinic of the Municipality of Havana, which evaluated the behaviour of the negative radiological examinations and their contribution to the collective dose as well as the associated detriment. 486 cases with radiographic examinations are reported over a period of four months. The information on individual cases is classified by type of radiographic examination and whether the outcome of the examination was positive or negative, the absorbed doses per organ and irradiated tissue, dose equivalent, collective and effective doses. The probability of the occurrence of a fatal cancer and associated genetic damage due to the examinations is also considered. 41% of the examinations performed were negative, with a collective dose of 11.35 manSv and 52.9 % of the total doses contributed for all the radiological examinations of the population studied

Loss of coolant accident. Past, present and future

International Nuclear Information System (INIS)

Cermak, J.O.

1978-01-01

The history of LOCA is covered from the original design basis, failure of the largest connecting pipe with no peak clad temperature limit through to the current design basis, double ended failure of the largest pipe in the primary system with a design peak clad temperature limit of 2200 0 F. Various obstacles along the way are addressed such as, degree of analytical sophisticaton, perplexing experimental results, the infamous 1971 semiscale tests, fuel densification and changes in USNRC evaluation models. In the future, it is projected that more reliance will be put on probabilistic evaluation of the LOCA with respect to both the accident analysis, reliability of the system and the probability of the accident itself. (author)

Future demand scenarios of Bangladesh power sector

International Nuclear Information System (INIS)

Mondal, Md. Alam Hossain; Boie, Wulf; Denich, Manfred

2010-01-01

Data on the future electricity demand is an essential requirement for planning the expansion of a power system. The purpose of this study is to provide a general overview of electricity consumption in Bangladesh, forecast sector-wise electricity demand up to 2035 considering the base year 2005, and compare the results with official projections. The Long-range Energy Alternative Planning (LEAP) model with three scenarios, namely low gross domestic product (GDP) growth, average GDP growth and high GDP growth, is applied in this study. In the low to high GDP growth scenarios, the extent of industrial restructuring and technical advancement is gradually increased. The findings have significant implications with respect to energy conservation and economic development. The study also compares the projected per capita electricity consumption in Bangladesh with the historical growth in several other developing countries. Such an evaluation can create awareness among the planners of power system expansion in Bangladesh to meet the high future demand.

The Future of Multicultural Social Work

Directory of Open Access Journals (Sweden)

Rowena Fong

2005-05-01

Full Text Available Multicultural social work has been evolving over the last forty years despite challenges in limited knowledge, insufficient resources, and inadequate infusion into the curriculum. Discussions continue about appropriate conceptual frameworks, culturally sensitive terms, traditional and indigenous practice approaches and treatments, and relevant outcome measures and evaluation methods. Future directions foster the inclusion of cultural values as strengths. Intersectionality guides practice approaches and systems of care. Service learning requirements, national ethnic resource centers, and ethnic resource centers, and ethnic studies dual degree programs are innovative initiatives yet to be fully integrated into social work curriculum.

Evaluation of the radiation field in the future circular collider detector

CERN Document Server

AUTHOR|(INSPIRE)INSPIRE-00211473; Cerutti, Francesco; Ferrari, Alfredo; Riegler, Werner; Vlachoudis, Vasilis; CERN. Geneva. ATS Department

2016-01-01

The radiation load on a detector at a 100 TeV proton-proton collider, that is being investigated within the Future Circular Collider (FCC) study, is presented. A peak luminosity of 30 1034 cm−2s−1 and a total integrated luminosity of 30 ab−1 are assumed for these radiation studies. A first concept of the detector foresees the presence of central and forward sub-detectors that provide acceptance up to |η|=6 inside a magnetic field generated by the combination of a central solenoid and two forward dipoles. This layout has been modelled and relevant fluence and dose distributions have been calculated using the FLUKA Monte Carlo code. Distributions of fluence rates are discussed separately for charged particles, neutrons and pho- tons. Dose and 1 MeV neutron equivalent fluence, for the accumulated integrated luminosity, are presented. The peak values of these quantities in the different sub-detectors are highlighted, in order to define the radiation tolerance requirements for the choice of possible technol...

Nonlinearity and intraday efficiency tests on energy futures markets

International Nuclear Information System (INIS)

Wang, Tao; Yang, Jian

2010-01-01

Using high frequency data, this paper first time comprehensively examines the intraday efficiency of four major energy (crude oil, heating oil, gasoline, natural gas) futures markets. In contrast to earlier studies which focus on in-sample evidence and assume linearity, the paper employs various nonlinear models and several model evaluation criteria to examine market efficiency in an out-of-sample forecasting context. Overall, there is evidence for intraday market inefficiency of two of the four energy future markets (heating oil and natural gas), which exists particularly during the bull market condition but not during the bear market condition. The evidence is also robust against the data-snooping bias and the model overfitting problem, and its economic significance can be very substantial. (author)

Nonlinearity and intraday efficiency tests on energy futures markets

Energy Technology Data Exchange (ETDEWEB)

Wang, Tao [Department of Economics, Queens College and the Graduate Center, The City University of New York, Flushing, NY 11367 (United States); Yang, Jian [The Business School, PO Box 173364, University of Colorado Denver, Denver, CO 80217-3364 (United States)

2010-03-15

Using high frequency data, this paper first time comprehensively examines the intraday efficiency of four major energy (crude oil, heating oil, gasoline, natural gas) futures markets. In contrast to earlier studies which focus on in-sample evidence and assume linearity, the paper employs various nonlinear models and several model evaluation criteria to examine market efficiency in an out-of-sample forecasting context. Overall, there is evidence for intraday market inefficiency of two of the four energy future markets (heating oil and natural gas), which exists particularly during the bull market condition but not during the bear market condition. The evidence is also robust against the data-snooping bias and the model overfitting problem, and its economic significance can be very substantial. (author)

Evaluating theories of bird song learning: implications for future directions.

Science.gov (United States)

Margoliash, D

2002-12-01

Studies of birdsong learning have stimulated extensive hypotheses at all levels of behavioral and physiological organization. This hypothesis building is valuable for the field and is consistent with the remarkable range of issues that can be rigorously addressed in this system. The traditional instructional (template) theory of song learning has been challenged on multiple fronts, especially at a behavioral level by evidence consistent with selectional hypotheses. In this review I highlight the caveats associated with these theories to better define the limits of our knowledge and identify important experiments for the future. The sites and representational forms of the various conceptual entities posited by the template theory are unknown. The distinction between instruction and selection in vocal learning is not well established at a mechanistic level. There is as yet insufficient neurophysiological data to choose between competing mechanisms of error-driven learning and reinforcement learning. Both may obtain for vocal learning. The possible role of sleep in acoustic or procedural memory consolidation, while supported by some physiological observations, does not yet have support in the behavioral literature. The remarkable expansion of knowledge in the past 20 years and the recent development of new technologies for physiological and behavioral experiments should permit direct tests of these theories in the coming decade.

Review & Analysis: Technological Impact on Future Air Force Personnel & Training: Distributed Collaborative Decision-Making, Volume II. Non-Copyrighted Literature Search

National Research Council Canada - National Science Library

Palmer, Barbara

1997-01-01

..., compared to that of a single individual. (2) The greatest detriment to collaborative distributed decision making is that we must rely on technology rather than face to face interactions, and subtleties of human communication may be lost. (3...

Driven by the future : Future time perspective across life domains and cultures

NARCIS (Netherlands)

Andre, L.

2018-01-01

Contemplating about the future is inevitable for our life and goal strivings. Consequently, Future Time Perspective (FTP) – individuals’ attitudes towards the future as a motivator for attitudes and behaviors – has been researched across disciplines and life domains. However, little is known about

European oil refining: strategies for a competitive future

International Nuclear Information System (INIS)

MacDonald, James.

1997-07-01

European Oil Refining investigates how the industry came to be in crisis and what the future holds. As well as an extensive analysis of past and present market shifts, the report predicts likely future developments and their consequences for investors. The report reviews the European oil sector in a global context, calculates the cost to refiners of key environmental legislation, assesses the problems caused by changing product demand and crude supply, examines possible solutions to the problems of low margins and overcapacity, evaluates the key players' main strategies to increase their competitiveness, analyses the western European oil refining industry by country, details the refinery operations of the major countries of central and eastern Europe, profiles 15 of the major oil companies and estimates the increase in investment required as a result of legislative and demand changes. (author)

FUTURE CLIMATE ANALYSIS

International Nuclear Information System (INIS)

R.M. Forester

2000-01-01

This Analysis/Model Report (AMR) documents an analysis that was performed to estimate climatic variables for the next 10,000 years by forecasting the timing and nature of climate change at Yucca Mountain (YM), Nevada (Figure l), the site of a potential repository for high-level radioactive waste. The future-climate estimates are based on an analysis of past-climate data from analog meteorological stations, and this AMR provides the rationale for the selection of these analog stations. The stations selected provide an upper and a lower climate bound for each future climate, and the data from those sites will provide input to the infiltration model (USGS 2000) and for the total system performance assessment for the Site Recommendation (TSPA-SR) at YM. Forecasting long-term future climates, especially for the next 10,000 years, is highly speculative and rarely attempted. A very limited literature exists concerning the subject, largely from the British radioactive waste disposal effort. The discussion presented here is one method, among many, of establishing upper and lower bounds for future climate estimates. The method used here involves selecting a particular past climate from many past climates, as an analog for future climate. Other studies might develop a different rationale or select other past climates resulting in a different future climate analog

FUTURE CLIMATE ANALYSIS

Energy Technology Data Exchange (ETDEWEB)

R.M. Forester

2000-03-14

This Analysis/Model Report (AMR) documents an analysis that was performed to estimate climatic variables for the next 10,000 years by forecasting the timing and nature of climate change at Yucca Mountain (YM), Nevada (Figure l), the site of a potential repository for high-level radioactive waste. The future-climate estimates are based on an analysis of past-climate data from analog meteorological stations, and this AMR provides the rationale for the selection of these analog stations. The stations selected provide an upper and a lower climate bound for each future climate, and the data from those sites will provide input to the infiltration model (USGS 2000) and for the total system performance assessment for the Site Recommendation (TSPA-SR) at YM. Forecasting long-term future climates, especially for the next 10,000 years, is highly speculative and rarely attempted. A very limited literature exists concerning the subject, largely from the British radioactive waste disposal effort. The discussion presented here is one method, among many, of establishing upper and lower bounds for future climate estimates. The method used here involves selecting a particular past climate from many past climates, as an analog for future climate. Other studies might develop a different rationale or select other past climates resulting in a different future climate analog.

White paper on future technologies

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-12-15

This book describes the role of technology and challenge of future like why we focus on future technologies and future, human being and technology, methodology on development for future technologies such as global monitoring system for investigation on environmental change, investigation of research front for paper and patent and COMPAS, and domestic and foreign organization for discover on future technologies. It also introduces KISTI selection future technologies 500 : healthy society, smart society, safety society, and future technologies 500.

Future Costs, Fixed Healthcare Budgets, and the Decision Rules of Cost-Effectiveness Analysis.

Science.gov (United States)

van Baal, Pieter; Meltzer, David; Brouwer, Werner

2016-02-01

Life-saving medical technologies result in additional demand for health care due to increased life expectancy. However, most economic evaluations do not include all medical costs that may result from this additional demand in health care and include only future costs of related illnesses. Although there has been much debate regarding the question to which extent future costs should be included from a societal perspective, the appropriate role of future medical costs in the widely adopted but more narrow healthcare perspective has been neglected. Using a theoretical model, we demonstrate that optimal decision rules for cost-effectiveness analyses assuming fixed healthcare budgets dictate that future costs of both related and unrelated medical care should be included. Practical relevance of including the costs of future unrelated medical care is illustrated using the example of transcatheter aortic valve implantation. Our findings suggest that guidelines should prescribe inclusion of these costs. Copyright © 2014 John Wiley & Sons, Ltd.

Energy future Santa Cruz: A citizens' plan for energy self-reliance

Science.gov (United States)

Cohn, J.; Stayton, R.

The results of a grassroots energy conservation project which involved more than 3,100 residents of Santa Cruz, California, is discussed. Citizens attended forums and town meetings to suggest ideas for solving the community's energy problems. These ideas were then evaluated by the Energy Future Advisory Board and compiled into the Energy Future Plan. The energy plan covers such topics as new residences, residential retrofit, automobile efficiency, farm efficiency, commercial greenhouses, local food production, commercial efficiency, land use planning, energy education and financing, and solar, wind, and ocean energy. An energy implementation guide and glossary are included.

Future Directions in Etiologic, Prevention, and Treatment Research for Eating Disorders

Science.gov (United States)

Stice, Eric; South, Kelsey; Shaw, Heather

2012-01-01

Significant advances have occurred regarding the understanding of etiologic processes that give rise to eating disorders and the design and evaluation of efficacious prevention programs and treatment interventions. Herein we offer suggestions regarding potentially fruitful directions for future research in these areas. We suggest it would be…

Risk Characterization for Future Training Scenarios at the Massachusetts Military Reservation (MMR), Final Results

National Research Council Canada - National Science Library

Zakikhani, Mansour; Dortch, Mark S; Gerald, Jeffrey A; Hawkins, Melanie S

2005-01-01

This study was conducted to evaluate potential human and ecological health risks associated with emission of pyrotechnic compounds during future training exercises at the Massachusetts Military Reservation...

Evaluation of proliferation resistance using the INPRO methodology

International Nuclear Information System (INIS)

Yang, Myung Seung; Park, Joo Hwan; Ko, Won Il; Song, Kee Chan; Choi, Kun Mo; Kim, Jin Kyoung

2007-01-01

The IAEA launched the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) and developed the INPRO Methodology to provide guidelines and to assess the characteristics of a future innovative nuclear energy system in areas such as safety, economics, waste management, and proliferation resistance. The proliferation resistance area of the INPRO Methodology is reviewed here, and modifications for further improvements are proposed. The evaluation metrics including the evaluation parameters, evaluation scales and acceptance limits are developed for a practical application of the methodology to assess the proliferation resistance. The proliferation resistant characteristics of the DUPIC fuel cycle are assessed by applying the modified INPRO Methodology based on the developed evaluation metrics and acceptance criteria. The evaluation procedure and the metrics can be utilized as a reference for an evaluation of the proliferation resistance of a future innovative nuclear energy system

Leaders as evaluators in public welfare service : drivers, barriers and risks

DEFF Research Database (Denmark)

Olesen, Kristian Gylling; Pallesen, Eva

2017-01-01

Paper fremlagt på EEC 12th EES Biennial Conference: Evaluation Futures in Europe and beyond. Connectivity, Innovation and Use. 26.-30. september 2016......Paper fremlagt på EEC 12th EES Biennial Conference: Evaluation Futures in Europe and beyond. Connectivity, Innovation and Use. 26.-30. september 2016...

A core competency-based objective structured clinical examination (OSCE) can predict future resident performance.

Science.gov (United States)

Wallenstein, Joshua; Heron, Sheryl; Santen, Sally; Shayne, Philip; Ander, Douglas

2010-10-01

This study evaluated the ability of an objective structured clinical examination (OSCE) administered in the first month of residency to predict future resident performance in the Accreditation Council for Graduate Medical Education (ACGME) core competencies. Eighteen Postgraduate Year 1 (PGY-1) residents completed a five-station OSCE in the first month of postgraduate training. Performance was graded in each of the ACGME core competencies. At the end of 18 months of training, faculty evaluations of resident performance in the emergency department (ED) were used to calculate a cumulative clinical evaluation score for each core competency. The correlations between OSCE scores and clinical evaluation scores at 18 months were assessed on an overall level and in each core competency. There was a statistically significant correlation between overall OSCE scores and overall clinical evaluation scores (R = 0.48, p competencies of patient care (R = 0.49, p competencies. An early-residency OSCE has the ability to predict future postgraduate performance on a global level and in specific core competencies. Used appropriately, such information can be a valuable tool for program directors in monitoring residents' progress and providing more tailored guidance. © 2010 by the Society for Academic Emergency Medicine.

Radiological impact of the Argentine Nuclear Programme

International Nuclear Information System (INIS)

Gonzalez, A.J.

1983-01-01

An assessment is made of the radiological impact resulting from the activities carried out so far under the Argentine Nuclear Programme, together with a prediction of the impact which could result from the future activities planned under that Programme. The average individual risks and the radiological detriment due to the various activities are determined in terms of the average individual effective dose equivalents and the collective effective dose equivalent commitments. The assessments cover exposures of occupationally exposed workers and the public. The data obtained indicate that both the risks and the resultant detriment are reasonably comparable with those derived from other similar programmes. Moreover, they clearly indicate that the radiological impact of the Programme is tending to decrease with time so that it can be assumed that the radiological impact per unit of practice will be even lower in future. (author)

Episodic memory and future thinking during early childhood: Linking the past and future.

Science.gov (United States)

Cuevas, Kimberly; Rajan, Vinaya; Morasch, Katherine C; Bell, Martha Ann

2015-07-01

Despite extensive examination of episodic memory and future thinking development, little is known about the concurrent emergence of these capacities during early childhood. In Experiment 1, 3-year-olds participated in an episodic memory hiding task ("what, when, where" [WWW] components) with an episodic future thinking component. In Experiment 2, a group of 4-year-olds (including children from Experiment 1) participated in the same task (different objects and locations), providing the first longitudinal investigation of episodic memory and future thinking. Although children exhibited age-related improvements in recall, recognition, and binding of the WWW episodic memory components, there were no age-related changes in episodic future thinking. At both ages, WWW episodic memory performance was higher than future thinking performance, and episodic future thinking and WWW memory components were unrelated. These findings suggest that the WWW components of episodic memory are potentially less fragile than the future components when assessed in a cognitively demanding task. © 2015 Wiley Periodicals, Inc.

Customer Satisfaction and Customer Loyalty as Predictors of Future Business Potential

DEFF Research Database (Denmark)

Eskildsen, Jacob Kjær; Kristensen, Kai

2007-01-01

This paper analyzes the relationship between customer satisfaction, customer loyalty and the future business potential of existing customers. The data for the analysis comes from the Danish Customer Satisfaction Index 2006. Here a total of app. 2000 private customers evaluated their...

Future Expectations of High School Students In Southeastern Turkey: Factors behind Future Expectations

Directory of Open Access Journals (Sweden)

Hüseyin Şimşek

2012-01-01

Full Text Available This study was conducted to identify various future expectations of high school students in southeastern Turkey and factors behind their expectations. The sample of the study, which had a descriptive and associational survey design consisted of 1106 students randomly selected from 54 different high schools located in nine cities in southeastern Turkey. Data were collected through the “Future Expectation Scale (FES” developed by the researcher. Results indicated that personal and professional future, educational future, economic future and social future expectations of high school students in southeastern Turkey were generally above the average level. According to the study, being a teacher and a doctor took the first place among several professions to be further preferred by high school students. It was also concluded that future expectations of high school students did not differ on gender, high school type, CGPA, level of mother education, father’s occupation, family income level, the number of siblings, receiving pre-school education, and language spoken at home. On the other hand, future expectations of high school students were found to differ on the city where students being taught, grade level, corporal punishment, and tendency toward being a dropout.

Medial Temporal Lobe Contributions to Episodic Future Thinking: Scene Construction or Future Projection?

Science.gov (United States)

Palombo, D J; Hayes, S M; Peterson, K M; Keane, M M; Verfaellie, M

2018-02-01

Previous research has shown that the medial temporal lobes (MTL) are more strongly engaged when individuals think about the future than about the present, leading to the suggestion that future projection drives MTL engagement. However, future thinking tasks often involve scene processing, leaving open the alternative possibility that scene-construction demands, rather than future projection, are responsible for the MTL differences observed in prior work. This study explores this alternative account. Using functional magnetic resonance imaging, we directly contrasted MTL activity in 1) high scene-construction and low scene-construction imagination conditions matched in future thinking demands and 2) future-oriented and present-oriented imagination conditions matched in scene-construction demands. Consistent with the alternative account, the MTL was more active for the high versus low scene-construction condition. By contrast, MTL differences were not observed when comparing the future versus present conditions. Moreover, the magnitude of MTL activation was associated with the extent to which participants imagined a scene but was not associated with the extent to which participants thought about the future. These findings help disambiguate which component processes of imagination specifically involve the MTL. Published by Oxford University Press 2016.

The design, results and future development of the National Energy Strategy Environmental Analysis Model (NESEAM)

International Nuclear Information System (INIS)

Fisher, R.E.; Boyd, G.A.; Breed, W.S.

1991-01-01

The National Energy Strategy Environmental Model (NESEAM) has been developed to project emissions for the National Energy Strategy (NES). Two scenarios were evaluated for the NES, a Current Policy Base Case and a NES Action Case. The results from the NES Actions Case project much lower emissions than the Current Policy Base Case. Future enhancements to NESEAM will focus on fuel cycle analysis, including future technologies and additional pollutants to model. NESEAM's flexibility will allow it to model other future legislative issues. 7 refs., 4 figs., 2 tabs

Long-lived hypopituitary Ames dwarf mice are resistant to the detrimental effects of high-fat diet on metabolic function and energy expenditure.

Science.gov (United States)

Hill, Cristal M; Fang, Yimin; Miquet, Johanna G; Sun, Liou Y; Masternak, Michal M; Bartke, Andrzej

2016-06-01

Growth hormone (GH) signaling stimulates the production of IGF-1; however, increased GH signaling may induce insulin resistance and can reduce life expectancy in both mice and humans. Interestingly, disruption of GH signaling by reducing plasma GH levels significantly improves health span and extends lifespan in mice, as observed in Ames dwarf mice. In addition, these mice have increased adiposity, yet are more insulin sensitive compared to control mice. Metabolic stressors such as high-fat diet (HFD) promote obesity and may alter longevity through the GH signaling pathway. Therefore, our objective was to investigate the effects of a HFD (metabolic stressor) on genetic mechanisms that regulate metabolism during aging. We show that Ames dwarf mice fed HFD for 12 weeks had an increase in subcutaneous and visceral adiposity as a result of diet-induced obesity, yet are more insulin sensitive and have higher levels of adiponectin compared to control mice fed HFD. Furthermore, energy expenditure was higher in Ames dwarf mice fed HFD than in control mice fed HFD. Additionally, we show that transplant of epididymal white adipose tissue (eWAT) from Ames dwarf mice fed HFD into control mice fed HFD improves their insulin sensitivity. We conclude that Ames dwarf mice are resistant to the detrimental metabolic effects of HFD and that visceral adipose tissue of Ames dwarf mice improves insulin sensitivity in control mice fed HFD. © 2016 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Evaluating electronic performance support systems: A methodology focused on future use-in-practice

NARCIS (Netherlands)

Collis, Betty; Verwijs, C.A.

1995-01-01

Electronic performance support systems, as an emerging type of software environment, present many new challenges in relation to effective evaluation. In this paper, a global approach to a 'usage-orientated' evaluation methodology for software product is presented, followed by a specific example of

Contextual Influences on Evaluative Style and its Effectiveness: Three Avenues for Future Research

NARCIS (Netherlands)

J. Noeverman (Jan); B.A.S. Koene (Bas)

2010-01-01

textabstractMany accounting studies have investigated the effects of differences in evaluative style on subordinate managers’ attitudes and performance. These studies have usually based the distinction of different evaluative styles on the extent to which a superior uses and relies on accounting

Energy in the world: The present situation and future options

International Nuclear Information System (INIS)

Rogner, H.H.

1989-01-01

It is reported that the most notable changes on the world energy scene since 1973 concerned the shift in OPEC's role from a base to a swing producer, the disruption of the fast market penetration of nuclear power and the impacts caused by the technical advances at essentially all stages of the energy system. Further, several parts of the world witnessed a strong environmental movement which attracted public attention to the conduct of the energy industry and its social implications and environmental consequences. The lecture illuminates these events in some detail and evaluate their impacts on present and future energy demand, supply and trade patterns. The future energy outlook includes two fundamentally different scenarios. Each scenario in itself appears internally consistent. The diverging projections of future energy demand and supply mixes underlying these scenarios are the result of the inclusion/omission of technical change or dynamics of technology into the analyses. 19 refs, 22 figs

Planned obsolescence publishing, technology, and the future of the academy

CERN Document Server

Fitzpatrick, Kathleen

2011-01-01

Academic institutions are facing a crisis in scholarly publishing at multiple levels: presses are stressed as never before, library budgets are squeezed, faculty are having difficulty publishing their work, and promotion and tenure committees are facing a range of new ways of working without a clear sense of how to understand and evaluate them. Planned Obsolescence is both a provocation to think more broadly about the academy’s future and an argument for reconceiving that future in more communally-oriented ways. Facing these issues head-on, Kathleen Fitzpatrick focuses on the technological changes—especially greater utilization of internet publication technologies, including digital archives, social networking tools, and multimedia—necessary to allow academic publishing to thrive into the future. But she goes further, insisting that the key issues that must be addressed are social and institutional in origin. Springing from original research as well as Fitzpatrick’s own hands-on experiments in ne...

Future reservoir management under climate change for the Mississippi River

International Nuclear Information System (INIS)

Asnaashari, Ahmad; Gharabaghi, Bahram; McBean, Edward A.; Kunjikutty, Sobhalatha; Lehman, Paul; Wade, Winston

2010-01-01

This paper is part of an ongoing research project designed to evaluate the effect of climate change on reservoir operation policies in the Mississippi Valley Conservation Authority. The study used the results from a first paper, including projected daily temperature and precipitation, for future streamflow calculation. This paper presented the development, calibration and validation of a rainfall-runoff NAM model for the Mississippi River watershed. The calibrated Mike11/NAM model was fed with predicted climatic data to generate long term future streamflow in the basin. Forecast flows were run in a Mike 11/HD model to estimate the corresponding lake levels. The storages and flows at Shabomeka Lake, Mazinaw Lake and Marble Lake were simulated. The results showed that climate change is likely to have implications for reservoir operations in the Mississippi River watershed, which will include changed water level regimes due to modifications in the projected future streamflow hydrograph to meet desired lake levels.

Factors affecting future specialty choice among medical students in Kuwait.

Science.gov (United States)

Al-Fouzan, Rawan; Al-Ajlan, Sarah; Marwan, Yousef; Al-Saleh, Mervat

2012-01-01

Choosing a medical specialty can be either a daunting and confusing experience for some medical students and junior doctors or a foregone conclusion to others. The aim of this study is to evaluate factors affecting future specialty choice among medical students in Kuwait University. A self-administered questionnaire was used to collect data from medical students registered in Kuwait University during the academic year 2011/2012. Chi-square test and logistic regression were used to test the association between deciding a future specialty and students' sociodemographic and academic factors. Of the 422 students approached, 387 (91.7%) decided to participate. A total of 144 (37.2%) students made a decision regarding their choice of future medical specialty. Pediatrics, general surgery, and cardiology were the most desired specialties - 18 (12.5%), 17 (11.8%), and 16 (11.1%) students requested these specialties, respectively. Only 61 (42.4%) of those who selected a future specialty received advice regarding their choice. Looking for a good treatment outcome for patients (66; 45.8%) and a challenging specialty (58; 40.3%) were the most influencing incentives when selecting a future specialty. Students in the clinical phase of their study were 3.014 (95% CI: 1.498-6.065) more likely to report on their decision regarding a future specialty compared to students in the basic medical sciences phase (p=0.002). A variety of factors appeared to inspire medical students in Kuwait to choose a future medical specialty. When identified, these factors can be used by mentors of medical students and directors of residency training programs to motivate students to choose specialties that are limited in Kuwait.

Ecological and valeological culture of future teacher: self-analisys of its completeness

Directory of Open Access Journals (Sweden)

Boychuk Yu. D.

2012-01-01

Full Text Available A theoretical ground is presented reflection-evaluation component to ecological and valeological cultures of future teacher. A component foresees developed the capacity of future teacher for an analysis and self-examination of formed to ecological and valeological culture, self-control and self-appraisal own, ecological and valeological conduct, his comprehension and self-regulation. It is marked that reflection mechanisms operate at formation of primary and auxiliary purposes. Directions of achievement a purpose are recommended to ecological and valeological to activity. Attention is accented on technologies of verification of knowledge, ability and skills.

Future Savvy

DEFF Research Database (Denmark)

Gordon, Adam

There's no shortage of predictions available to organizations looking to anticipate and profit from future events or trends. Apparently helpful forecasts are ubiquitous in everyday communications such as newspapers and business magazines, and in specialized sources such as government and think......-tank forecasts, consultant reports, and stock-market guides. These resources are crucial, but they are also of very mixed quality. How can decision-makers know which predictions to take seriously, which to be wary of, and which to throw out entirely? Future Savvy provides analytical filters to judging predictive...... systematic "forecast filtering" to reveal strengths and weakness in the predictions they face. Future Savvy empowers both business and policy/government decision-makers to use forecasts wisely and so improve their judgment in anticipating opportunities, avoiding threats, and managing uncertainty....

Governance of the future

DEFF Research Database (Denmark)

Galløe, Lotte Rannveig

a different future for both parents and children. Thus, the approach to PMTO as a technology of the future indicates its expected prevalence in the future and its attempt to reach in to the future becoming of the child. The technology’s involvement of the relatives and its orientation towards shaping......In my presentation I will explore the concept, ‘technology of the future’, in public governance. Public governance within social services aims at changing the existing conditions for the marginalized citizens including children with special needs. I pose the question: what happens if public...... governance seek to chance the possible future conditions and targets the marginalized child’s relatives? Parent Management Training (PMTO) is studied as a technology of the future that expands and transforms governance. PMTO targets parents with aggressive and asocial children and aims to “create the parent...

Gated communities and urban sustainability: taking a closer look at the future

CSIR Research Space (South Africa)

Landman, K

2000-08-01

Full Text Available residents and to be detrimental to long-term urban sustainability and political stability. It could just be that the very measure that is implemented to address crime and instability after a while becomes a major source of conflict20. • Urban... impact on the quality of life in an area and on building a liveable and vibrant city. It could also lead to the formation of political pressure groups and attempts to pressurise the local government into making certain decisions. It could not only...

The worker of the future. A system outlines the competencies its employees will need.

Science.gov (United States)

Hill, K; Meyer, B

1998-01-01

In 1993, Sisters of Mercy Health System-St. Louis (SMHS), having asked itself what kind of employees it would need in the twenty-first century, established a Worker of the Future Task Force to develop tentative answers. The task force began by making projections concerning healthcare, studying the strategic plans of SMHS's members, and surveying its employees. It learned that the system should help workers see how change could benefit them. Next, the task force studied the cultural history of the Sisters of Mercy, developing from it Six Guiding Principles for the evaluation of employee performance. From these principles, the task force derived Twelve Competencies that SMHS will seek in future workers. In 1995 the system's education leaders, with the aid of an internal training organization, decided to develop 17 training modules based on these guiding principles and competencies. Since then, more than 85 SMHS employees have been trained to help coworkers develop customer service skills and other competencies. SMHS has also incorporated the competencies in its job descriptions and performance evaluations, added the Worker of the Future curriculum to its orientation program for new employees, and is currently developing Worker of the Future training sessions for human resources personnel who interview prospective employees.

The future of energy generation sector in Brazil

International Nuclear Information System (INIS)

Assis, Gino de

2000-01-01

The importance of energy on the life of modern man is evaluated considering environmental and strategic issues. Energetic crisis that happened on the recent past of Brazil and United States of America are reviewed and analysed in the light of the particular strategic matters of each country. A tentative projection of the profile of the electrical energy generator industry of Brazil is done based on the past experiences, on the present scenario and on the future potentials. (author)

California's Drought - Stress test for the future

Science.gov (United States)

Lund, J. R.

2014-12-01

The current California drought is in its third dry years, with this year being the third driest years in a 106-year record. This drought occurs at a time when urban, agricultural, and environmental water demands have never been greater. This drought has revealed the importance of more quantitative evaluation and methods for water assessment and management. All areas of water and environmental management are likely to become increasingly stressed, and have essentially drought-like conditions, in the future, as California's urban, agricultural, and environmental demands continue to expand and as the climate changes. In the historical past, droughts have pre-viewed stresses developing in the future and helped focus policy-makers, the public, and stakeholders on preparing for these developing future conditions. Multi-decade water management strategies are often galvinized by drought. Irrigation was galvanized by California droughts in the 1800s, reservoir systems by the 1928-32 drought, urban water conservation by the 1976-77 drought, and water markets by the 1988-92 drought. With each drought, demands for tighter accounting, rights, and management have increased. This talk reviews the prospects and challenges for increased development and use of water data and systems analysis in the service of human and environmental water demands in California's highly decentralized water management system, and the prospects if these challenges are not more successfully addressed.

The current status of theory evaluation in nursing.

Science.gov (United States)

Im, Eun-Ok

2015-10-01

To identify the current status of theory evaluation in nursing and provide directions for theory evaluation for future development of theoretical bases of nursing discipline. Theory evaluation is an essential component in development of nursing knowledge, which is a critical element in development of nursing discipline. Despite earlier significant efforts for theory evaluation in nursing, a recent decline in the number of theory evaluation articles was noted and there have been few updates on theory evaluation in nursing. Discussion paper. A total of 58 articles published from 2003-2014 were retrieved through searches using the PUBMED, PsyInfo and CINAHL. The articles were sorted by the area of evaluation and analysed to identify themes reflecting the theory evaluation process. Diverse ways of theory evaluation need to be continuously used in future theory evaluation efforts. Six themes reflecting the theory evaluation process were identified: (a) rarely using existing theory evaluation criteria; (b) evaluating specifics; (c) using various statistical analysis methods; (d) developing instruments; (e) adopting in practice and education; and (f) evaluating mainly middle-range theories and situation-specific theories. © 2015 John Wiley & Sons Ltd.

Ghosts of the past and dreams of the future: the impact of temporal focus on responses to contextual ingroup devaluation.

Science.gov (United States)

Rabinovich, Anna; Morton, Thomas A

2012-03-01

The authors investigated the impact of temporal focus on group members' responses to contextual ingroup devaluation. Four experimental studies demonstrated that following an induction of negative ingroup evaluation, participants primed with a past temporal focus reported behavioral intentions more consistent with this negative appraisal than participants primed with a future temporal focus. This effect was apparent only when a negative (but not a positive) evaluation was induced, and only among highly identified group members. Importantly, the interplay between temporal focus and group identification on relevant intentions was mediated by individual self-esteem, suggesting that focus on the future may be conducive to separating negative ingroup appraisals from individual self-evaluations. Taken together, the findings suggest that high identifiers' responses to ingroup evaluations may be predicated on their temporal focus: A focus on the past may lock such individuals within their group's history, whereas a vision of the future may open up opportunities for change.

Teledermatology. Current status and future directions.

Science.gov (United States)

Whited, J D

2001-01-01

Teledermatology is becoming an increasingly common means of delivering dermatologic healthcare worldwide and will almost certainly play a greater role in the future. The type of technology used distinguishes the 2 modes of teledermatology consultation. The store and forward technique uses still digital images generated by a digital camera. Consultations of this type are considered asynchronous since the images are obtained, sent, and reviewed at different times. In contrast, real-time interactive consultations are synchronous. Patients and clinicians interact in real-time through an audio-video communication link. Each modality has its advantages and disadvantages, and studies appear in the literature that assess both technologies. Although diagnostic reliability (precision) assessments for teledermatology are subject to limitations, existing information indicates that both store and forward and real-time interactive technology result in reliable diagnostic outcomes when compared with clinic-based evaluations. Less information regarding diagnostic accuracy is available; however, one evaluation that used store and forward technology found comparable diagnostic accuracy between teledermatology consultations and clinic-based examinations. Currently, little information is available regarding cost effectiveness and patient outcomes. Existing evidence, while inconclusive, suggests that teledermatology may be more costly than traditional clinic-based care, especially when using real-time interactive technology. Teledermatology has been shown to have utility as a triage mechanism for determining the urgency or need for a clinic-based consultation. Overall, patients appear to accept teledermatology and are satisfied with it as a means of obtaining healthcare. Clinicians have also generally reported positive experiences with teledermatology. Future studies that focus on cost effectiveness, patient outcomes, and patient and clinician satisfaction will help further define the

Current and future prospects for the application of systematic theoretical methods to the study of problems in physical oceanography

Energy Technology Data Exchange (ETDEWEB)

Constantin, A., E-mail: adrian.constantin@kcl.ac.uk [Department of Mathematics, King' s College London, Strand, London WC2R 2LS (United Kingdom); Faculty of Mathematics, University of Vienna, Oskar-Morgenstern-Platz 1, 1090 Vienna (Austria); Johnson, R.S., E-mail: r.s.johnson@ncl.ac.uk [School of Mathematics & Statistics, Newcastle University, Newcastle upon Tyne NE1 7RU (United Kingdom)

2016-09-07

Highlights: • Systematic theoretical methods in studies of equatorial ocean dynamics. • Linear wave-current interactions in stratified flows. • Exact solutions – Kelvin waves, azimuthal non-uniform currents. • Three-dimensional nonlinear currents. • Hamiltonian formulation for the governing equations and for structure-preserving/enhancing approximations. - Abstract: This essay is a commentary on the pivotal role of systematic theoretical methods in physical oceanography. At some level, there will always be a conflict between theory and experiment/data collection: Which is pre-eminent? Which should come first? This issue appears to be particularly marked in physical oceanography, to the extreme detriment of the development of the subject. It is our contention that the classical theory of fluids, coupled with methods from the theory of differential equations, can play a significant role in carrying the subject, and our understanding, forward. We outline the philosophy behind a systematic theoretical approach, highlighting some aspects of equatorial ocean dynamics where these methods have already been successful, paving the way for much more in the future and leading, we expect, to the better understanding of this and many other types of ocean flow. We believe that the ideas described here promise to reveal a rich and beautiful dynamical structure.

Future industrial issues for ANDRA

International Nuclear Information System (INIS)

Auverlot, D.

1998-01-01

ANDRA manages industrially 90 % in volume of radioactive waste produced in France. This is short life waste of low and medium activity. In compliance with the law of 1991, which transformed it into a public body with an industrial and commercial character, ANDRA also heads aspect 2 of the research into the 10 % of remaining highly active long life waste, by attempting to evaluate the possibilities of storing it in deep geological layers, either reversibly or irreversibly. The industrial issues of the future for ANDRA can be in different forms, following three meeting of major importance for ANDRA and for the producers of nuclear waste. These are: the meeting of 2006, at the end of which, in compliance with the law of 1991, the Parliament must re-examine the question of the management of highly active, long life waste; the renewal of nuclear facilities; the future meeting concerning future generations. However, whatever these different stage and whatever the different types of waste considered, the single and major challenge with which ANDRA is confronted is to prove that it is capable of providing a sure danger-free management of all radioactive waste. In this context, it appears necessary, today, to intensify research into aspects 1 and 3 of the law of 1991, to respect the balance of the three aspects. This in fact constitutes an essential pledge of the credibility of the procedure instituted by the law: at present, to clearly specify the research into surface storing in the short or long terms; building the three laboratories, the authorization for which has been subject to public inquiry. And also to keep, for 2006, the largest possible choice of the geological environment. (author)

Future Contingents

DEFF Research Database (Denmark)

Øhrstrøm, Peter; Hasle., Per F. V.

2015-01-01

contingent statements. The problem of future contingents is interwoven with a number of issues in theology, philosophy, logic, semantics of natural language, computer science, and applied mathematics. The theological issue of how to reconcile the assumption of God's foreknowledge with the freedom and moral...... accountability of human beings has been a main impetus to the discussion and a major inspiration to the development of various logical models of time and future contingents. This theological issue is connected with the general philosophical question of determinism versus indeterminism. Within logic, the relation...... about the future. Finally, it should be mentioned that temporal logic has found a remarkable application in computer science and applied mathematics. In the late 1970s the first computer scientists realised the relevance of temporal logic for the purposes of computer science (see Hasle and Øhrstrøm 2004)....

Future Contingents

DEFF Research Database (Denmark)

Øhrstrøm, Peter; Hasle., Per F. V.

2011-01-01

contingent statements. The problem of future contingents is interwoven with a number of issues in theology, philosophy, logic, semantics of natural language, computer science, and applied mathematics. The theological issue of how to reconcile the assumption of God's foreknowledge with the freedom and moral...... accountability of human beings has been a main impetus to the discussion and a major inspiration to the development of various logical models of time and future contingents. This theological issue is connected with the general philosophical question of determinism versus indeterminism. Within logic, the relation...... about the future. Finally, it should be mentioned that temporal logic has found a remarkable application in computer science and applied mathematics. In the late 1970s the first computer scientists realised the relevance of temporal logic for the purposes of computer science (see Hasle and Øhrstrøm 2004)....

On the Future High Energy Colliders

Energy Technology Data Exchange (ETDEWEB)

Shiltsev, Vladimir [Fermilab

2015-09-28

High energy particle colliders have been in the forefront of particle physics for more than three decades. At present the near term US, European and international strategies of the particle physics community are centered on full exploitation of the physics potential of the Large Hadron Collider (LHC) through its high-luminosity upgrade (HL-LHC). A number of the next generation collider facilities have been proposed and are currently under consideration for the medium and far-future of accelerator-based high energy physics. In this paper we offer a uniform approach to evaluation of various accelerators based on the feasibility of their energy reach, performance potential and cost range.

Development of Biopesticides and Future Opportunities.

Science.gov (United States)

Glare, Travis R; Gwynn, Roma L; Moran-Diez, Maria E

2016-01-01

Biopesticides, pesticides based on living organisms or their extracts, are increasing in sales around the world, as synthetic pesticides are less available and environmental and health issues drive new approaches. Despite the increasing sales and use, there are still limitations that restrict more widespread uptake, such as slow to kill, cost, difficulties of production, lack of appropriate formulations, and reputation based on previous poor performance of biopesticides. Regulation continues to be problematic in many countries, as the processes are designed for evaluating chemistry rather than live organisms. Biopesticides do have a bright future, given the amount of investment currently in the area, improving products and growing need.

Computers in nuclear medicine - current trends and future directions

International Nuclear Information System (INIS)

Anon.

1994-01-01

Previously, a decision to purchase computing equipment for nuclear medicine usually required evaluation of the 'local' needs. With the advent of Pacs and state of the art computer techniques for image acquisition and manipulation, purchase and subsequent application is to become much more complex. Some of the current trends and future possibilities which may influence the choice and operation of computers within and outside the nuclear medicine environment is discussed. (author)

Fun Teaching: The Key to the Future Climatology

Science.gov (United States)

Mulvey, G.

2016-12-01

In general meteorology is a science of immediate impact. What will the weather be tomorrow or next week? Climatology and climate change is the science of our long range past and future. Decisions made in the past, now, and in the future on climate change issues did and will continue to impact the global climate. It is essential that current and future generations understand the causes of climate change to make informed decisions regarding individual and government actions needed to mitigate human impacts on the future climate. The university challenge is make climatology an exciting and dynamic adventure into the past, present and future. Instructor and supporting organizations have stepped outside the "old yellow notes" approach to enable students to progress beyond remember, understand, and apply; to analyze, evaluate and create. Responding to this instructional challenge by shifting instructional techniques and tools to a new paradigm does not happen overnight. The instructional strategies to make this jump are known in general, but not in specific. This paper deals with examples of how to translate the instructional strategies into practice in ways that are fun for students and instructors. Techniques to be described include interactive discussions, debates and team challenges, such as: - Describing continental climates during past geological periods - In-class teams debates on legislature to control/modify human CO2 releases Low or no cost teaching aids such as video clips, demonstrations, specimens, and experiments will be described with outcomes and resources interest. Some examples to be discussed are - Tree cookies, cross sections - Ocean core smear slide samples of diatoms, foraminifera, etc. - Ice pack/glacial melt experiments - Glacial flow and interpreting glacial ice cores experiment - Field trips to observe geological strata and geological samples - Storytelling - the shared experiences of each instructor

Dams, Hydrology and Risk in Future River Management

Science.gov (United States)

Wegner, D. L.

2017-12-01

Across America there are over 80,000 large to medium dams and globally the number is in excess of 800,000. Currently there are over 1,400 dams and diversion structures being planned or under construction globally. In addition to these documented dams there are thousands of small dams populating watersheds. Governments, agencies, native tribes, private owners and regulators all have a common interest in safe dams. Often dam safety is characterized as reducing structural risk while providing for maximum operational flexibility. In the 1970's there were a number of large and small dam failures in the United States. These failures prompted the federal government to issue voluntary dam safety guidelines. These guidelines were based on historic information incorporated into a risk assessment process to analyze, evaluate and manage risk with the goal to improve the quality of and support of dam management and safety decisions. We conclude that historic and new risks need to be integrated into dam management to insure adequate safety and operational flexibility. A recent assessment of the future role of dams in the United States premises that future costs such as maintenance or removal beyond the economic design life have not been factored into the long-term operations or relicensing of dams. The converging risks associated with aging water storage infrastructure, multiple dams within watersheds and uncertainty in demands policy revisions and an updated strategic approach to dam safety. Decisions regarding the future of dams in the United States may, in turn, influence regional water planning and management. Leaders in Congress and in the states need to implement a comprehensive national water assessment and a formal analysis of the role dams play in our water future. A research and national policy agenda is proposed to assess future impacts and the design, operation, and management of watersheds and dams.

Evaluating the Tensile Properties of Aluminum Foundry Alloys through Reference Castings-A Review.

Science.gov (United States)

Anilchandra, A R; Arnberg, Lars; Bonollo, Franco; Fiorese, Elena; Timelli, Giulio

2017-08-30

The tensile properties of an alloy can be exploited if detrimental defects and imperfections of the casting are minimized and the microstructural characteristics are optimized through several strategies that involve die design, process management and metal treatments. This paper presents an analysis and comparison of the salient characteristics of the reference dies proposed in the literature, both in the field of pressure and gravity die-casting. The specimens produced with these reference dies, called separately poured specimens, are effective tools for the evaluation and comparison of the tensile and physical behaviors of Al-Si casting alloys. Some of the findings of the present paper have been recently developed in the frame of the European StaCast project whose results are complemented here with some more recent outcomes and a comprehensive analysis and discussion.

Evaluating the Tensile Properties of Aluminum Foundry Alloys through Reference Castings—A Review

Science.gov (United States)

Anilchandra, A.R.; Arnberg, Lars; Bonollo, Franco; Fiorese, Elena

2017-01-01

The tensile properties of an alloy can be exploited if detrimental defects and imperfections of the casting are minimized and the microstructural characteristics are optimized through several strategies that involve die design, process management and metal treatments. This paper presents an analysis and comparison of the salient characteristics of the reference dies proposed in the literature, both in the field of pressure and gravity die-casting. The specimens produced with these reference dies, called separately poured specimens, are effective tools for the evaluation and comparison of the tensile and physical behaviors of Al-Si casting alloys. Some of the findings of the present paper have been recently developed in the frame of the European StaCast project whose results are complemented here with some more recent outcomes and a comprehensive analysis and discussion. PMID:28867796

Potential Future Igneous Activity at Yucca Mountain, Nevada

International Nuclear Information System (INIS)

Cline, M.; Perry, F.; Valentine, G.; Smistad, E.

2005-01-01

Location, timing, and volumes of post-Miocene volcanic activity, along with expert judgment, provide the basis for assessing the probability of future volcanism intersecting a proposed repository for nuclear waste at Yucca Mountain, Nevada. Analog studies of eruptive centers in the region that may represent the style and extent of possible future igneous activity at Yucca Mountain have aided in defining the consequence scenarios for intrusion into and eruption through a proposed repository. Modeling of magmatic processes related to magma/proposed repository interactions has been used to assess the potential consequences of a future igneous event through a proposed repository at Yucca Mountain. Results of work to date indicate future igneous activity in the Yucca Mountain region has a very low probability of intersecting the proposed repository. Probability of a future event intersecting a proposed repository at Yucca Mountain is approximately 1.7 x 10 -8 per year. Since completion of the Probabilistic Volcanic Hazard Assessment (PVHA) in 1996, anomalies representing potential buried volcanic centers have been identified from aeromagnetic surveys. A re-assessment of the hazard is currently underway to evaluate the probability of intersection in light of new information and to estimate the probability of one or more volcanic conduits located in the proposed repository along a dike that intersects the proposed repository. US Nuclear Regulatory Commission regulations for siting and licensing a proposed repository require that the consequences of a disruptive event (igneous event) with annual probability greater than 1 x 10 -8 be evaluated. Two consequence scenarios are considered: (1) igneous intrusion-poundwater transport case and (2) volcanic eruptive case. These scenarios equate to a dike or dike swarm intersecting repository drifts containing waste packages, formation of a conduit leading to a volcanic eruption through the repository that carries the contents of

Silage review: Recent advances and future uses of silage additives.

Science.gov (United States)

Muck, R E; Nadeau, E M G; McAllister, T A; Contreras-Govea, F E; Santos, M C; Kung, L

2018-05-01

to apply a direct-fed microbial strain at ensiling, have it survive ensiling, and multiply during feed out. Chemical additives traditionally have fallen in 2 groups. Formic acid causes direct acidification, suppressing clostridia and other undesired bacteria and improving protein preservation during ensiling. On the other hand, sorbic, benzoic, propionic, and acetic acids improve silage aerobic stability at feed out through direct inhibition of yeasts and molds. Current research has focused on various combinations of these chemicals to improve both aerobic stability and animal productivity. Enzyme additives have been added to forage primarily to breakdown plant cell walls at ensiling to improve silage fermentation by providing sugars for the LAB and to enhance the nutritive value of silage by increasing the digestibility of cell walls. Cellulase or hemicellulase mixtures have been more successful at the former than the latter. A new approach focused on Lb. buchneri producing ferulic acid esterase has also had mixed success in improving the efficiency of silage digestion. Another new enzyme approach is the application of proteases to corn silage to improve starch digestibility, but more research is needed to determine the feasibility. Future silage additives are expected to directly inhibit clostridia and other detrimental microorganisms, mitigate high mycotoxin levels on harvested forages during ensiling, enhance aerobic stability, improve cell wall digestibility, increase the efficiency of utilization of silage nitrogen by cattle, and increase the availability of starch to cattle. Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Contents of a regulatory strategy for assessing future human actions in the safety evaluation of a repository for spent fuels

International Nuclear Information System (INIS)

Wilmot, R.D.; Wickham, S.M.; Galson, D.A.

2001-08-01

The objective of this report is to discuss issues that should be considered in the development of a regulatory strategy for assessing future human actions in any forthcoming license application for a deep repository for spent fuel in Sweden and for sites of other repositories. The report comprises an outline of key issues concerning the treatment of future human actions in safety assessment, reviews of regulatory developments, recent safety assessments and supporting studies, and international initiatives on the treatment of future human actions in safety assessment, and the principal elements of a regulatory strategy. Performance assessments (PAs) are generally accepted as providing illustrations of system performance under given sets of assumptions. The results of PAs are clearer and easier to understand if certain large uncertainties are accounted for by determining performance under several different sets of assumptions or scenarios, each of which defines a possible evolution of the disposal system. A number of assumptions can be made that would restrict the scope of an assessment without reducing the credibility of the corresponding safety case. Reducing speculation about technological development, by assuming that the techniques used in future human activities are similar to those currently in use in the region or at similar sites, will simplify the assessment. A distinction is generally made between inadvertent and intentional intrusion, with intentional activities excluded because society cannot protect future populations from their own actions if they understand the potential consequences. A division of human activities into 'recent and ongoing' and 'future' activities considers not only the timing of the activities but also the degree of control or influence that can be imposed on them. Recent and ongoing human activities are those that affect an area beyond the immediate vicinity of the disposal facility and which neither the proponent nor the regulator

Predicting future land cover change and its impact on streamflow and sediment load in a trans-boundary river basin

Directory of Open Access Journals (Sweden)

J. Wang

2018-06-01

Full Text Available Sediment load can provide very important perspective on erosion of river basin. The changes of human-induced vegetation cover, such as deforestation or afforestation, affect sediment yield process of a catchment. We have already evaluated that climate change and land cover change changed the historical streamflow and sediment yield, and land cover change is the main factor in Red river basin. But future streamflow and sediment yield changes under potential future land cover change scenario still have not been evaluated. For this purpose, future scenario of land cover change is developed based on historical land cover changes and land change model (LCM. In addition, future leaf area index (LAI is simulated by ecological model (Biome-BGC based on future land cover scenario. Then future scenarios of land cover change and LAI are used to drive hydrological model and new sediment rating curve. The results of this research provide information that decision-makers need in order to promote water resources planning efforts. Besides that, this study also contributes a basic framework for assessing climate change impacts on streamflow and sediment yield that can be applied in the other basins around the world.

Dynamics of values held by future sports teachers: a longitudinal study

African Journals Online (AJOL)

The dynamics of personal values and values pertaining to the meaning of life held by future sport teachers was investigated. The two surveys used were the Rokeach Value Survey for identification of the most important personal values and the Leontiev Life Meaning Orientations Test for the evaluation of values pertaining to ...

Factors affecting future specialty choice among medical students in Kuwait

Directory of Open Access Journals (Sweden)

Rawan Al-Fouzan

2012-12-01

Full Text Available Background: Choosing a medical specialty can be either a daunting and confusing experience for some medical students and junior doctors or a foregone conclusion to others. The aim of this study is to evaluate factors affecting future specialty choice among medical students in Kuwait University. Methods: A self-administered questionnaire was used to collect data from medical students registered in Kuwait University during the academic year 2011/2012. Chi-square test and logistic regression were used to test the association between deciding a future specialty and students’ sociodemographic and academic factors. Results: Of the 422 students approached, 387 (91.7% decided to participate. A total of 144 (37.2% students made a decision regarding their choice of future medical specialty. Pediatrics, general surgery, and cardiology were the most desired specialties – 18 (12.5%, 17 (11.8%, and 16 (11.1% students requested these specialties, respectively. Only 61 (42.4% of those who selected a future specialty received advice regarding their choice. Looking for a good treatment outcome for patients (66; 45.8% and a challenging specialty (58; 40.3% were the most influencing incentives when selecting a future specialty. Students in the clinical phase of their study were 3.014 (95% CI: 1.498–6.065 more likely to report on their decision regarding a future specialty compared to students in the basic medical sciences phase (p=0.002. Conclusion : A variety of factors appeared to inspire medical students in Kuwait to choose a future medical specialty. When identified, these factors can be used by mentors of medical students and directors of residency training programs to motivate students to choose specialties that are limited in Kuwait.

Queering Aging Futures

Directory of Open Access Journals (Sweden)

Linn J. Sandberg

2017-08-01

Full Text Available This paper explores the potential for cultural gerontology to extend its ideas of diversity in aging experiences by opening space to rethink conceptions of successful aging futures. We propose a ‘queering’ of aging futures that disrupts the ways that expectations of a good later life and happy aging are seen to adhere to some bodies and subjectivities over others. Drawing on feminist, queer, and crip theories, we build on existing critiques of ‘successful aging’ to interrogate the assumptions of heteronormativity, able-bodiedness and able-mindedness that shape the dividing lines between success and failure in aging, and which inform attempts to ‘repair’ damaged futures. Conclusions suggest that recognizing diversity in successful aging futures is important in shaping responses to the challenges of aging societies, and presents an opportunity for critical cultural gerontology to join with its theoretical allies in imagining more inclusive alternatives.

Component processes underlying future thinking.

Science.gov (United States)

D'Argembeau, Arnaud; Ortoleva, Claudia; Jumentier, Sabrina; Van der Linden, Martial

2010-09-01

This study sought to investigate the component processes underlying the ability to imagine future events, using an individual-differences approach. Participants completed several tasks assessing different aspects of future thinking (i.e., fluency, specificity, amount of episodic details, phenomenology) and were also assessed with tasks and questionnaires measuring various component processes that have been hypothesized to support future thinking (i.e., executive processes, visual-spatial processing, relational memory processing, self-consciousness, and time perspective). The main results showed that executive processes were correlated with various measures of future thinking, whereas visual-spatial processing abilities and time perspective were specifically related to the number of sensory descriptions reported when specific future events were imagined. Furthermore, individual differences in self-consciousness predicted the subjective feeling of experiencing the imagined future events. These results suggest that future thinking involves a collection of processes that are related to different facets of future-event representation.

Brain Activity in Valuation Regions while Thinking about the Future Predicts Individual Discount Rates

Science.gov (United States)

Cooper, Nicole; Kim, B. Kyu; Zauberman, Gal

2013-01-01

People vary widely in how much they discount delayed rewards, yet little is known about the sources of these differences. Here we demonstrate that neural activity in ventromedial prefrontal cortex (VMPFC) and ventral striatum (VS) when human subjects are asked to merely think about the future—specifically, to judge the subjective length of future time intervals—predicts delay discounting. High discounters showed lower activity for longer time delays, while low discounters showed the opposite pattern. Our results demonstrate that the correlation between VMPFC and VS activity and discounting occurs even in the absence of choices about future rewards, and does not depend on a person explicitly evaluating future outcomes or judging their self-relevance. This suggests a link between discounting and basic processes involved in thinking about the future, such as temporal perception. Our results also suggest that reducing impatience requires not suppression of VMPFC and VS activity altogether, but rather modulation of how these regions respond to the present versus the future. PMID:23926268

Imagining the future self: how age influences our future self images

DEFF Research Database (Denmark)

Salgado, Sinue; Berntsen, Dorthe; Rathbone, Clare

This study examines the impact of age on the quantitative features of future selves. A representative sample of the Danish population from different age-groups generated images of up to eight future selves which were dated and rated for vividness, positivity and emotional intensity. There were...... significant differences across age-groups on all ratings of the future selves. Positive correlations with age were found for vividness and emotional intensity, whereas positivity and distance from present correlated negatively. There was no correlation between age and number of selves generated. The findings...

The Academic Journal: Has it a Future?

Directory of Open Access Journals (Sweden)

Gaby Weiner

2001-03-01

Full Text Available This article examines the current state of the academic journal. It does so for a number of reasons: the increasing expense of paper journals; the advent of electronic publishing; the use of publication in journals as an indicator of research quality (in addition to disseminating knowledge within a discipline and consequent criticisms of systems of peer review and evaluation of scholarship; emergent issues of equity and access; and evidence of malpractice. These issues taken together constitute a critique of, and challenge to, the process whereby research papers become journal articles, which has in the past been viewed as unproblematic and straightforward. This paper brings together a wide range of literature in order to inform discussion about the future of the academic journal. It briefly examines the origins of the academic journal and then provides a comprehensive overview of current debates concerning how academic journals work today. In so doing, it raises questions about decisions that will need to be taken regarding the continuity or otherwise of the conventional academic journal, and how publishing practices may change in the future.

The art of creating futures. Practical theology and a strategic research sensitivity for the future

NARCIS (Netherlands)

van den Berg, J.A.; Ganzevoort, R.R.

2014-01-01

This paper explores a futures perspective for practical theology. Although there are some examples of a future orientation, a systematic futures perspective has not been developed. Building on futures studies (including predictive studies on foresight and design and architecture studies), the

Designing a Methodology for Future Air Travel Scenarios

Science.gov (United States)

Wuebbles, Donald J.; Baughcum, Steven L.; Gerstle, John H.; Edmonds, Jae; Kinnison, Douglas E.; Krull, Nick; Metwally, Munir; Mortlock, Alan; Prather, Michael J.

1992-01-01

-subsonic future fleet. The methodology, procedures, and recommendations for the development of future HSCT and the subsonic fleet scenarios used for this evaluation are discussed.

A Land-use Approach for Capturing Future Trip Generating Poles

Directory of Open Access Journals (Sweden)

Iraklis Stamos

2015-12-01

Full Text Available Changes in the usage of a particular urban or regional area have immediate effects on transportation, such as the development of a new multimodal terminal within a city, or the creation of a business park in its outskirts. Thus far, this correlation has been under-researched at a national level in Greece. As a result, its effects on trip generation and passenger flows has been underestimated at the planning level, leading to the implementation of projects that are neither viable nor sustainable. This paper proposes that land use changes ought to be considered in tandem with transport-related changes at the planning stage. To this effect, we present a three-step methodology for an integrated approach to capturing future trip generation: the identification of future trip-generating poles within the study area; the development of scenarios related to the probability of these changes occurring and their potential magnitude; an estimation of future trends in passenger flows. The methodology is applied to the Metropolitan area of Thessaloniki, Greece. Using data obtained from development plans, national statistical services and research projects’ and studies’ findings, we estimate future trip-generation subsequent to land use change. Data is processed and evaluated by a local experts’ group, representing various key-disciplines of the area’s planning stakeholders.

Does Parent-Child Interaction Therapy Reduce Future Physical Abuse? A Meta-Analysis

Science.gov (United States)

Kennedy, Stephanie C.; Kim, Johnny S.; Tripodi, Stephen J.; Brown, Samantha M.; Gowdy, Grace

2016-01-01

Objective: To use meta-analytic techniques to evaluating the effectiveness of parent-child interaction therapy (PCIT) at reducing future physical abuse among physically abusive families. Methods: A systematic search identified six eligible studies. Outcomes of interest were physical abuse recurrence, child abuse potential, and parenting stress.…

Uncertain Future, Deliberate Action: Proceedings of the Circumpolar Climate Change Summit

International Nuclear Information System (INIS)

2001-01-01

Northern environments and communities are entering a period of unprecedented change. Emissions of greenhouse gases due to human activities are altering the atmosphere and are expected to change global climate in ways that may be detrimental to our environmental, social and economic systems. An increasing body of observation provides convincing evidence of a warming world, and there is strong evidence that the warming observed over the last 50 years is attributable to human activity. While climate change science is, without a doubt, complicated and not all views about climate change are universally accepted by all, in northern Canada, climate change is no longer an abstract idea. There is strong scientific and anecdotal evidence that the northern environment is responding to new climatic conditions, evidence that strongly supports the current Intergovernmental Panel on Climate Change (IPCC) models and predictions on global climatic change. This conference, 'Uncertain future, deliberate action -- Climate Change in the Circumpolar North' was organized to provide northerners, and those with an interest in the North, an opportunity to learn more about climate change from internationally recognized experts, business leaders, professionals and community leaders who shared their ideas about climate change and the circumpolar North. Discussions, talks, exhibits, and posters were structured around the three themes of 'Understanding Climate Change in the North: (1) State of knowledge and new directions in research'; (2) 'Responding to climate change in the North: Measures to reduce greenhouse gas emissions and our vulnerability to a changing climate'; and (3) 'Policy and planning responses to climate change in the North'. This special issue of the NORTHERN REVIEW contains a report, and the presentations and discussions at the Summit, along with papers that complement the main themes

The image-interpretation-workstation of the future: lessons learned

Science.gov (United States)

Maier, S.; van de Camp, F.; Hafermann, J.; Wagner, B.; Peinsipp-Byma, E.; Beyerer, J.

2017-05-01

In recent years, professionally used workstations got increasingly complex and multi-monitor systems are more and more common. Novel interaction techniques like gesture recognition were developed but used mostly for entertainment and gaming purposes. These human computer interfaces are not yet widely used in professional environments where they could greatly improve the user experience. To approach this problem, we combined existing tools in our imageinterpretation-workstation of the future, a multi-monitor workplace comprised of four screens. Each screen is dedicated to a special task in the image interpreting process: a geo-information system to geo-reference the images and provide a spatial reference for the user, an interactive recognition support tool, an annotation tool and a reporting tool. To further support the complex task of image interpreting, self-developed interaction systems for head-pose estimation and hand tracking were used in addition to more common technologies like touchscreens, face identification and speech recognition. A set of experiments were conducted to evaluate the usability of the different interaction systems. Two typical extensive tasks of image interpreting were devised and approved by military personal. They were then tested with a current setup of an image interpreting workstation using only keyboard and mouse against our image-interpretationworkstation of the future. To get a more detailed look at the usefulness of the interaction techniques in a multi-monitorsetup, the hand tracking, head pose estimation and the face recognition were further evaluated using tests inspired by everyday tasks. The results of the evaluation and the discussion are presented in this paper.

Alternatives for forage evaluation in ruminants

NARCIS (Netherlands)

Gosselink, J.M.J.

2004-01-01

The objective of this thesis was to validate and to compare in situ and in vitro techniques with in vivo data. These techniques were also evaluated for future and practical use in feed evaluation for ruminants. The techniques were compared using the digestion data of 98 forages and the energy

Evaluation of Radiation-induced Class V Dental Caries in Patients with Head and Neck Cancers Undergoing Radiotherapy.

Science.gov (United States)

Mohammadi, Narmin; Seyednejad, Farshad; Oskoee, Parnian Alizadeh; Savadi Oskoee, Siavash; Ebrahimi Chaharom, Mohammad Esmaeil

2008-01-01

Salivary glands are very susceptible to radiation and any disturbances in their function are detrimental to the hard tissues in the oral cavity. The aim of this study was to evaluate posterior class V dental caries in patients with head and neck cancers undergoing radiotherapy. In this study, twenty seven patients undergoing conventional radiotherapy were included. Class V dental caries of posterior teeth in these patients were evaluated in three intervals: before treatment, 3 weeks after the initiation of the treatment, and at the end of the treatment. Differences of mean caries activity between intervals were evaluated using paired sample t-test. There were no class V decays prior to radiotherapy. Mean percentage of class V caries three weeks after radiotherapy and at the end of radiotherapy were 28.42% ± 14.41 and 67.05% ± 19.02, respectively. There were statistically signifi-cant differences in mean values among three stages (P = 0.00025). The results of the present study re-vealed that radiotherapy in patients with head and neck cancers causes class V dental caries on posteri-or teeth.

CRITERIA OF FORMATION OF SOCIAL-PEDAGOGICAL COMPETENCE OF FUTURE PRIMARY SCHOOL TEACHERS IN INCLUSIVE SECONDARY SCHOOL

Directory of Open Access Journals (Sweden)

Zoia Shevtsiv

2017-03-01

Full Text Available The article aims to justify the formation of criteria and indicators of social-pedagogical competence of the future teachers of primary school of inclusive comprehensive school and to determine its level of development. The objectives are to determine the status of the development problems of professional competence of teachers in inclusive education; essence and structural components of social-pedagogical competence of future primary school teacher of inclusive comprehensive school; criteria, indicators and levels of social-pedagogical competence of future primary school teacher of inclusive comprehensive schools. The education system in Ukraine is gradually transition to inclusive education. Inclusive comprehensive school is being created. It requires a highly qualified primary school teacher who co-teaches regulatory children and children with disability. The article is grounded the necessity of social-pedagogical competence of future teachers of primary school of inclusive comprehensive schools. The essence of social-pedagogical competence of future primary school teacher of inclusive comprehensive schools is defined. The structural components of social-pedagogical competence are characterized. Scientific papers on the issue of formation of competence of experts in various fields are analyzed. The pronunciation for selection and justification criteria and parameters of formation of professional competence is overviewed. The group of the criteria suggested by various scientists from the evaluation of the formation of professional competence of specialists in different fields is considered. The criteria and parameters of evaluating the levels of social-pedagogical competence of future teachers of primary school in inclusive comprehensive schools are selected on the base of the analysis of modern achievements of scientists. Future prospects of research is in developing of a method of diagnosing the levels of social-pedagogical competence of

Clinical leadership for high-quality care: developing future ward leaders.

Science.gov (United States)

Enterkin, Judith; Robb, Elizabeth; McLaren, Susan

2013-03-01

This paper reports upon the development, delivery and evaluation of a leadership programme for aspiring Ward Leaders in one National Health Service Trust in England. The ward sister role is fundamental to quality patient care and clinical leadership, however the role is increasingly difficult to recruit to. A lack of formal preparation and skills development for the role has been widely acknowledged. An evaluation of a programme of education for leadership. Three cohorts (n = 60) completed the programme. Semi-structured questionnaires were completed by participants (n = 36: 60%) at the conclusion of the programme. Qualitative data from questionnaires was analysed using a thematic approach. Participants reported increased political, organizational and self-awareness, increased confidence, feelings of empowerment and the ability to empower others. Opportunities for networking with peers were valued within the action learning approach. For some participants, career intentions were clarified through reflection. The majority of participants had benefited from the leadership programme and valued this development as an empowering preparation for future careers. Investment in leadership preparation for future ward sister roles is strongly recommended as part of a strategy designed to enhance quality improvement, career path development, workforce empowerment and retention. © 2012 Blackwell Publishing Ltd.

Bladder augmentation without integration of intact bowel segments: critical review and future perspectives.

NARCIS (Netherlands)

Gurocak, S.; Gier, R.P.E. de; Feitz, W.F.J.

2007-01-01

PURPOSE: We evaluated the long-term results of autoaugmentation in the pediatric age group and summarized technical adaptations, experimental options and future perspectives for treating these patients. MATERIALS AND METHODS: A directed MEDLINE literature review was performed to assess different

Safeguarding future large-scale plutonium bulk handling facilities

International Nuclear Information System (INIS)

1979-01-01

The paper reviews the current status, advantages, limitations and probable future developments of material accountancy and of containment and surveillance. The major limitations on the use of material accountancy in applying safeguards to future plants arise from the uncertainty with which flows and inventories can be measured (0.5 to 1.0%), and the necessity to carry out periodical physical inventories to determine whether material has been diverted. The use of plant instrumentation to determine in-process inventories has commenced and so has the development of statistical methods for the evaluations of the data derived from a series of consecutive material balance periods. The limitations of accountancy can be overcome by increased use of containment and surveillance measures which have the advantage that they are independent of the operator's actions. In using these measures it will be necessary to identify the credible diversion paths, build in sufficient redundancy to reduce false alarm rates, develop automatic data recording and alarming

Future Climate Analysis

International Nuclear Information System (INIS)

James Houseworth

2001-01-01

This Analysis/Model Report (AMR) documents an analysis that was performed to estimate climatic variables for the next 10,000 years by forecasting the timing and nature of climate change at Yucca Mountain (YM), Nevada (Figure 1), the site of a potential repository for high-level radioactive waste. The future-climate estimates are based on an analysis of past-climate data from analog meteorological stations, and this AMR provides the rationale for the selection of these analog stations. The stations selected provide an upper and a lower climate bound for each future climate, and the data from those sites will provide input to the infiltration model (USGS 2000) and for the total system performance assessment for the Site Recommendation (TSPA-SR) at YM. Forecasting long-term future climates, especially for the next 10,000 years, is highly speculative and rarely attempted. A very limited literature exists concerning the subject, largely from the British radioactive waste disposal effort. The discussion presented here is one method, among many, of establishing upper and lower bounds for future climate estimates. The method used here involves selecting a particular past climate from many past climates, as an analog for future climate. Other studies might develop a different rationale or select other past climates resulting in a different future climate analog. Revision 00 of this AMR was prepared in accordance with the ''Work Direction and Planning Document for Future Climate Analysis'' (Peterman 1999) under Interagency Agreement DE-AI08-97NV12033 with the U.S. Department of Energy (DOE). The planning document for the technical scope, content, and management of ICN 01 of this AMR is the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (BSC 2001a). The scope for the TBV resolution actions in this ICN is described in the ''Technical Work Plan for: Integrated Management of Technical Product Input Department''. (BSC 2001b, Addendum B

Future Climate Analysis

Energy Technology Data Exchange (ETDEWEB)

James Houseworth

2001-10-12

This Analysis/Model Report (AMR) documents an analysis that was performed to estimate climatic variables for the next 10,000 years by forecasting the timing and nature of climate change at Yucca Mountain (YM), Nevada (Figure 1), the site of a potential repository for high-level radioactive waste. The future-climate estimates are based on an analysis of past-climate data from analog meteorological stations, and this AMR provides the rationale for the selection of these analog stations. The stations selected provide an upper and a lower climate bound for each future climate, and the data from those sites will provide input to the infiltration model (USGS 2000) and for the total system performance assessment for the Site Recommendation (TSPA-SR) at YM. Forecasting long-term future climates, especially for the next 10,000 years, is highly speculative and rarely attempted. A very limited literature exists concerning the subject, largely from the British radioactive waste disposal effort. The discussion presented here is one method, among many, of establishing upper and lower bounds for future climate estimates. The method used here involves selecting a particular past climate from many past climates, as an analog for future climate. Other studies might develop a different rationale or select other past climates resulting in a different future climate analog. Revision 00 of this AMR was prepared in accordance with the ''Work Direction and Planning Document for Future Climate Analysis'' (Peterman 1999) under Interagency Agreement DE-AI08-97NV12033 with the U.S. Department of Energy (DOE). The planning document for the technical scope, content, and management of ICN 01 of this AMR is the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (BSC 2001a). The scope for the TBV resolution actions in this ICN is described in the ''Technical Work Plan for: Integrated Management of Technical

Current and future industrial energy service characterizations

Energy Technology Data Exchange (ETDEWEB)

Krawiec, F.; Thomas, T.; Jackson, F.; Limaye, D.R.; Isser, S.; Karnofsky, K.; Davis, T.D.

1980-10-01

Current and future energy demands, end uses, and cost used to characterize typical applications and resultant services in the industrial sector of the United States and 15 selected states are examined. A review and evaluation of existing industrial energy data bases was undertaken to assess their potential for supporting SERI research on: (1) market suitability analysis, (2) market development, (3) end-use matching, (3) industrial applications case studies, and (4) identification of cost and performance goals for solar systems and typical information requirements for industrial energy end use. In reviewing existing industrial energy data bases, the level of detail, disaggregation, and primary sources of information were examined. The focus was on fuels and electric energy used for heat and power purchased by the manufacturing subsector and listed by 2-, 3-, and 4-digit SIC, primary fuel, and end use. Projections of state level energy prices to 1990 are developed using the energy intensity approach. The effects of federal and state industrial energy conservation programs on future industrial sector demands were assessed. Future end-use energy requirements were developed for each 4-digit SIC industry and were grouped as follows: (1) hot water, (2) steam (212 to 300/sup 0/F, each 100/sup 0/F interval from 300 to 1000/sup 0/F, and greater than 1000/sup 0/F), and (3) hot air (100/sup 0/F intervals). Volume I details the activities performed in this effort.

Prophylactic cranial irradiation may impose a detrimental effect on overall survival of patients with nonsmall cell lung cancer: a systematic review and meta-analysis.

Directory of Open Access Journals (Sweden)

Shuan-shuan Xie

Full Text Available To determine the role of brain metastases (BM and overall survival (OS in patients with non-small cell lung cancer (NSCLC by performing a meta-analysis of the RCTs (randomized controlled clinical trials and non-RCTs (non-randomized controlled clinical trials published in the literature.A meta-analysis was performed using trials identified through PubMed, EMBASE and Cochrane databases. Two investigators independently assessed the quality of the trials and extracted data. The outcomes included BM, OS, median survival (MS, response rate (RR, Hazard ratios (HRs and odds ratios (ORs, and their 95% confidence intervals (CIs were pooled using ReMan software.Twelve trials (6 RCTs and 6 non-RCTs involving 1,718 NSCLC patients met the inclusion criteria. They were grouped on the basis of study design for separate Meta-analyses. The results showed that prophylactic cranial irradiation (PCI reduced the risk of BM as compared with non-PCI in NSCLC patients (OR = 0.30, 95% [CI]: 0.21-0.43, p<0.00001. However, HRs for OS favored non-PCI (HR = 1.19, 95% [CI]: 1.06-1.33, p = 0.004, without evidence of heterogeneity between the studies.Our results suggest that although PCI decreased the risk of BM, it may impose a detrimental effect on OS of NSCLC patients.

The Perceived Benefits of a Preparing Future Faculty Program and Its Effect on Job Satisfaction, Confidence, and Competence

Science.gov (United States)

Wurgler, Emily; VanHeuvelen, Jane S.; Rohrman, Shawna; Loehr, Annalise; Grace, Matthew K.

2014-01-01

The training of effective instructors and future faculty members is a critical component of doctoral programs in sociology. Many universities and departments have instituted a single course, course sequence, or certification program dedicated to the preparation of future academic faculty. This article evaluates the efficacy of one such program,…

The potential natural vegetation of eastern Africa distribution, conservation and future changes

DEFF Research Database (Denmark)

van Breugel, Paulo

and sustainable management of the natural environment. There is therefore an urgent need for information that allow us to assess the current status of the region’s natural environment and to predict how this may change under future climates. This thesis aims to improve our knowledge on natural vegetation...... and how this is likely to change under different climate change scenarios. Chapter 4 presents an environmental gap analysis to prioritize conservation efforts in eastern Africa, based on an evaluation of the environmental representativeness of protected areas and an assessment of the level of threat...... distribution in eastern African, examine how this may change under future climates, and how this can be used to identify conservation priorities in the region. Chapter 1 presents a brief overview of the concept of the potential natural vegetation (PNV), synthesizes the general findings and discusses future...

Maturity effects in energy futures

Energy Technology Data Exchange (ETDEWEB)

Serletis, Apostolos (Calgary Univ., AB (CA). Dept. of Economics)

1992-04-01

This paper examines the effects of maturity on future price volatility and trading volume for 129 energy futures contracts recently traded in the NYMEX. The results provide support for the maturity effect hypothesis, that is, energy futures prices to become more volatile and trading volume increases as futures contracts approach maturity. (author).