WorldWideScience

Sample records for european allergy research

  1. Research needs in allergy

    DEFF Research Database (Denmark)

    Papadopoulos, Nikolaos G; Agache, Ioana; Bavbek, Sevim

    2012-01-01

    ABSTRACT: In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health...... in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21st century.The European Academy of Allergy and Clinical Immunology (EAACI) is the leading professional organization in the field of allergy, promoting...... excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients' Associations (EFA) is a non-profit network of allergy, asthma and Chronic...

  2. European Surveillance System on Contact Allergies (ESSCA)

    DEFF Research Database (Denmark)

    Uter, W; Amario-Hita, J C; Balato, A

    2017-01-01

    BACKGROUND: Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, new products or formulations and regulatory intervention, the spectrum of contact sensitization changes....... OBJECTIVE: To evaluate the current spectrum of contact allergy to allergens present in the European baseline series (EBS) across Europe. METHODS: Retrospective analysis of data collected by the European Surveillance System on Contact Allergies (ESSCA, www.essca-dc.org) in consecutively patch-tested patients......, 2013/14, in 46 departments in 12 European countries. RESULTS: Altogether, 31 689 patients were included in the analysis. Compared to a similar analysis in 2004, the prevalence of contact allergy to methylisothiazolinone went up to around 20% in several departments. In comparison, contact allergy...

  3. Seasonal Allergies: Diagnosis, Treatment & Research

    Science.gov (United States)

    ... this page please turn JavaScript on. Feature: Seasonal Allergies Diagnosis, Treatment & Research Past Issues / Spring 2015 Table of Contents Diagnosis Testing for Allergies Knowing exactly what you are allergic to can ...

  4. GA(2)LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma 'epidemic'

    NARCIS (Netherlands)

    Bousquet, J.; Burney, P. G.; Zuberbier, T.; Cauwenberge, P. V.; Akdis, C. A.; Bindslev-Jensen, C.; Bonini, S.; Fokkens, W. J.; Kauffmann, F.; Kowalski, M. L.; Lodrup-Carlsen, K.; Mullol, J.; Nizankowska-Mogilnicka, E.; Papadopoulos, N.; Toskala, E.; Wickman, M.; Anto, J.; Auvergne, N.; Bachert, C.; Bousquet, P. J.; Brunekreef, B.; Canonica, G. W.; Carlsen, K. H.; Gjomarkaj, M.; Haahtela, T.; Howarth, P.; Lenzen, G.; Lotvall, J.; Radon, K.; Ring, J.; Salapatas, M.; Schünemann, H. J.; Szczecklik, A.; Todo-Bom, A.; Valovirta, E.; von Mutius, E.; Zock, J. P.

    2009-01-01

    Allergic diseases represent a major health problem in Europe. They are increasing in prevalence, severity and costs. The Global Allergy and Asthma European Network (GA(2)LEN), a Sixth EU Framework Program for Research and Technological Development (FP6) Network of Excellence, was created in 2005 as

  5. Fighting Allergies with Research and Information

    Science.gov (United States)

    ... Navigation Bar Home Current Issue Past Issues Fighting Allergies with Research and Information Past Issues / Summer 2006 ... Director An interview with Anthony S. Fauci Are seasonal allergies on the rise? If so, why? There has ...

  6. A European survey on donor deferral for allergy

    DEFF Research Database (Denmark)

    Garraud, O; Martin, C; Haddad, A

    2017-01-01

    Allergy accounts to near 0.5% of all reported transfusion adverse events. The responsibility of blood components themselves and - therefore - of blood donors is still questioned. The European Community undertook a large international survey to address the consistency and homogeneity of medical...... selection of blood donors with regard to the risk of allergy, and especially of transferring allergy to recipients. This short report presents the salient points of the survey, stressing that there is inconsistency in addressing the allergy question within countries or systems, with paths of improvement....

  7. European symposium on precision medicine in allergy and airways diseases

    DEFF Research Database (Denmark)

    Muraro, A; Fokkens, W J; Pietikainen, S

    2015-01-01

    David Borrelli and with active participation of the European Respiratory Society (ERS), the European Federations of Allergy and Airways Diseases Patients Associations (EFA), the Global Allergy and Asthma European Network (Ga2len), Allergic Rhinitis and Its Impact on Asthma (ARIA) and the Respiratory....... This report summarizes the key messages delivered during the symposium by the speakers, including the EU Commissioner for Health and Food Safety Vitenys Andriukaitis. The Commissioner underscored the need for optimal patient care in Europe, supporting joint action plans for disease prevention, patient...... the epidemic of Allergy and Asthma in Europe. The socio-economic impact of allergies and chronic airways diseases cannot be underestimated, as they represent the most frequently diagnosed chronic non-communicable diseases in the EU. Despite the fact that 30% of the total European population is nowadays...

  8. European symposium on precision medicine in allergy and airways diseases

    DEFF Research Database (Denmark)

    Muraro, A; Fokkens, W J; Pietikainen, S

    2015-01-01

    suffering from allergies and asthma, more than half of these patients are deprived from adequate diagnosis and treatment. Precision Medicine represents a novel approach in medicine, embracing 4 key features: personalized care based on molecular, immunologic and functional endotyping of the disease......On 14 October 2015, the European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS) and the European Medical Association (EMA) organized a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP......, with participation of the patient in the decision making process of therapeutic actions, and taking into account predictive and preventive aspects of the treatment. Implementation of Precision Medicine into clinical practice may help to achieve the arrest of the Epidemic of Allergies and Chronic Airways Diseases...

  9. European Symposium on Precision Medicine in Allergy and Airways Diseases

    DEFF Research Database (Denmark)

    Muraro, A; Fokkens, W J; Pietikainen, S

    2016-01-01

    : personalized care based on molecular, immunologic and functional endotyping of the disease, with participation of the patient in the decision making process of therapeutic actions, and considering predictive and preventive aspects of the treatment. Implementation of Precision Medicine into clinical practice......The European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS) and the European Medical Association (EMA) organized, on 14 October 2015, a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP...... the most frequently diagnosed chronic non-communicable diseases in the EU. 30% of the total European population is suffering from allergies and asthma, and more than half are deprived from adequate diagnosis and treatment. Precision Medicine represents a novel approach, embracing 4 key features...

  10. A mutually beneficial collaboration between the European Academy of Allergy and Clinical Immunology Junior Members and Clinical and Translational Allergy.

    Science.gov (United States)

    Tomazic, Peter Valentin; Graessel, Anke; Silva, Diana; Eguiluz-Gracia, Ibon; Guibas, George V; Grattan, Clive; Bousquet, Jean; Tsilochristou, Olympia

    2016-01-01

    The European Academy of Allergy and Clinical Immunology (EAACI) Junior Members (JM) comprise the largest EAACI section with around 4000 clinicians and scientists under 35 years of age working in the field of allergy and clinical immunology. The Junior Member collaboration with Clinical and Translational Allergy Journal is a mutually beneficial relationship providing Junior Members of EAACI with excellent opportunities to publish their work in the Journal, enhance their visibility in their respective field, and get involved with Journal-related activities and processes. In the future, this collaboration will grow, not only by the consolidation of these activities, but also by the implementation of new initiatives, such as a platform for discussing and/or publishing Junior Members' dissertations in the Journal. From the CTA perspective, the collaboration presents an opportunity to promote a new generation of allergists with experience of conducting and presenting research, with improved skills in critical review.

  11. Allergies

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Allergies KidsHealth / For Teens / Allergies What's in this article? ... or Allergies? Dealing With Allergies Print What Are Allergies? Allergies are abnormal immune system reactions to things ...

  12. European Symposium on Precision Medicine in Allergy and Airways Diseases: Report of the European Union Parliament Symposium (October 14, 2015)

    NARCIS (Netherlands)

    Muraro, A.; Fokkens, W. J.; Pietikainen, S.; Borrelli, D.; Agache, I.; Bousquet, J.; Costigliola, V.; Joos, G.; Lund, V. J.; Poulsen, L. K.; Price, D.; Rolland, C.; Zuberbier, T.; Hellings, P. W.

    2016-01-01

    The European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS), and the European Medical Association (EMA) organized, on October 14, 2015, a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP

  13. Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology

    DEFF Research Database (Denmark)

    Muraro, A; Lemanske, Robert F; Castells, M

    2017-01-01

    This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology and the ......This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology...... and the American Academy of Allergy, Asthma and Immunology, which aims to synchronize the European and American approaches to allergy care. Precision medicine is an emerging approach for disease treatment based on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlying...

  14. Contact allergy to ingredients of topical medications : results of the European Surveillance System on Contact Allergies (ESSCA), 2009-2012

    NARCIS (Netherlands)

    Uter, Wolfgang; Spiewak, Radoslaw; Cooper, Susan M.; Wilkinson, Mark; Sanchez Perez, Javier; Schnuch, Axel; Schuttelaar, Marie-Louise

    2016-01-01

    PurposeThe aim of this study was to give an overview of the prevalence of contact allergy to active ingredients and excipients of topical medications across Europe. MethodsRetrospective analysis of data collected by the European Surveillance System on Contact Allergies () with substances applied to

  15. Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group

    DEFF Research Database (Denmark)

    Bruze, Magnus; Isaksson, Marléne; Gruvberger, Birgitta

    2014-01-01

    , and that for IQ Chambers(®) was 25 µl. RESULTS: Contact allergy to MCI/MI at 100 and 200 ppm was found in 1.2% and 2.1% of patients, respectively (p more contact allergy than the presently used concentration of 100 ppm (dose...... 0.003 mg/cm(2)), without resulting in more adverse reactions. MCI/MI at 200 ppm should therefore be considered for inclusion in the European baseline test series....

  16. A European Research Area

    International Nuclear Information System (INIS)

    Caro, R.

    2001-01-01

    This article is a summary of the presentation of the European Commissioner, Philippe Busquen, to the European Parliament (beginning of year 2000) with the proposal and method for a revival of the Research and Development in this wider sense in the European Union. The starting point of his thesis is that Europe performs less, and more disorderly, activities in this field that her main competitors. USA and Japan. His basic proposal is a larger coordination among the european research projects, with a previous phase of informatics intoxicator among the european research centres and the cross-linked participation, real of virtual in the experiments and projects. (Author)

  17. European Symposium on Precision Medicine in Allergy and Airways Diseases: Report of the European Union Parliament Symposium (October 14, 2015).

    Science.gov (United States)

    Muraro, A; Fokkens, W J; Pietikainen, S; Borrelli, D; Agache, I; Bousquet, J; Costigliola, V; Joos, G; Lund, V J; Poulsen, L K; Price, D; Rolland, C; Zuberbier, T; Hellings, P W

    2016-05-01

    The European Academy of Allergy and Clinical Immunology (EAACI), the European Rhinologic Society (ERS), and the European Medical Association (EMA) organized, on October 14, 2015, a symposium in the European Parliament in Brussels on Precision Medicine in Allergy and Airways Diseases, hosted by MEP David Borrelli, and with active participation of the EU Commissioner for Health and Food Safety Vytenis Andriukaitis, MEP Sirpa Pietikainen, Chair of the European Parliament Interest Group on Allergy and Asthma, the European Respiratory Society (ERS), the European Federations of Allergy and Airways Diseases Patients Associations (EFA), the Global Allergy and Asthma European Network (Ga2len), Allergic Rhinitis and Its Impact on Asthma (ARIA), and the Respiratory Effectiveness Group (REG). The socioeconomic impact of allergies and chronic airways diseases cannot be underestimated, as they represent the most frequently diagnosed chronic noncommunicable diseases in the EU; 30% of the total European population is suffering from allergies and asthma, and more than half are deprived from adequate diagnosis and treatment. Precision medicine represents a novel approach, embracing four key features: personalized care based on molecular, immunologic, and functional endotyping of the disease, with participation of the patient in the decision-making process of therapeutic actions, and considering predictive and preventive aspects of the treatment. Implementation of precision medicine into clinical practice may help to achieve the arrest of the epidemic of allergies and chronic airways diseases. Participants underscored the need for optimal patient care in Europe, supporting joint action plans for disease prevention, patient empowerment, and cost-effective treatment strategies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Prevalence of Contact Allergy to p-Phenylenediamine in the European General Population

    NARCIS (Netherlands)

    Diepgen, Thomas L.; Naldi, Luigi; Bruze, Magnus; Cazzaniga, Simone; Schuttelaar, Marie-Louise; Elsner, Peter; Goncalo, Margarida; Ofenloch, Robert; Svensson, Ake

    Population-based studies on contact allergy to p-phenylenediamine (PPD) are scarce. A cross-sectional study was performed to assess the prevalence of contact allergy to PPD and its risk factors in the general population of 5 European countries. A total of 10,425 subjects were interviewed, and a

  19. The European Union CREATE project: a model for international standardization of allergy diagnostics and vaccines

    NARCIS (Netherlands)

    Chapman, Martin D.; Ferreira, Fatima; Villalba, Mayte; Cromwell, Oliver; Bryan, Donna; Becker, Wolf-Meinhard; Fernández-Rivas, Montserrat; Durham, Stephen; Vieths, Stefan; van Ree, Ronald; Aalbers, M.; Notten, S.; Ooievaar-de Heer, P.; Ferreira, F.; Gademaier, G.; Wallner, M.; Villalba, M.; Rodriguez, R.; Becker, W.-M.; Eberhardt, F.; Lepp, U.; Raulf-Heimsoth, M.; Valenta, R.; Focke, M.; Bryan, D.; Dolman, C.; Das, R. G.; Vieths, S.; Fötisch, K.; Di Felice, G.; Pini, C.; Cromwell, O.; Fiebig, H.; Weber, B.; van Schijndel, H.; Dorpema, J. W.; Marco, F. M.; Monsalve, R.; Barber, D.; Caldas, E. Fernandez; Moingeon, P.; Didierlaurent, A.; André, C.; Kroon, A.; Neubauer, A.; Chapman, M.; Vailes, L.; Tsay, A.; Durham, S.; Custovic, A.; Simpson, B.; Knulst, A.; Rivas, M. Fernández; Mancebo, E. Gonzalez; Bahima, A. Cistero; Moncin, M. M. San Miguel; Mari, A.; Kinaciyan, T.; Quiralte, J.; Pauli, G.; de Blay, F.; Purohit, A.; Rak, S.

    2008-01-01

    Allergen measurements are used extensively in the formulation of allergy diagnostics and vaccines, yet no purified international allergen standards are available for calibration purposes. The aims of the European Union CREATE project were to develop international standards with verifiable allergen

  20. European Union Energy Research

    International Nuclear Information System (INIS)

    Valdalbero, D.R.; Schmitz, B.; Raldow, W.; Poireau, M.

    2007-01-01

    This article presents an extensive state of the art of the energy research conducted at European Union level between 1984 and 2006, i.e. from the first to the sixth European Community Framework Programmes (FP1-FP6) for Research, Technological Development and Demonstration (RTD and D). The FP is the main legal tool and financial instrument of EU RTD and D policy. It sets the objectives, priorities and budgets for a period of several years. It has been complemented over time with a number of policy oriented initiatives and notably with the launch of the European Research Area. FP7 will cover the period 2007-2013 and will have a total budget of more than euros 50 billion. Energy has been a main research area in Europe since the founding Treaties (European Coal and Steel Community, European Atomic Energy Community-Euratom and European Economic Community), and energy RTD and D has always been a substantial part of common EU research. Nevertheless, when inflation and successive European enlargements are taken into account, over time the RTD and D effort in the field of energy has decreased significantly in relative terms. In nominal terms it has remained relatively stable at about euros 500 million per year. For the next years (FP7), it is expected that energy will still represent about 10 % of total EU research effort but with an annual budget of more than euros 800 million per year. This article presents a detailed review of the thematic areas and budget in both European nuclear energy research (fusion and fission) and non-nuclear energy research (energy efficiency/rational use of energy, fossil fuels, CO 2 capture and storage, fuel cells and hydrogen, renewable energy sources, strategic energy research/socio-economy). (authors)

  1. Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology.

    Science.gov (United States)

    Muraro, A; Lemanske, R F; Castells, M; Torres, M J; Khan, D; Simon, H-U; Bindslev-Jensen, C; Burks, W; Poulsen, L K; Sampson, H A; Worm, M; Nadeau, K C

    2017-07-01

    This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology, which aims to synchronize the European and American approaches to allergy care. Precision medicine is an emerging approach for disease treatment based on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlying the disease. Although significant progress has been made in defining endotypes for asthma, definitions of endotypes for food and drug allergy or for anaphylaxis lag behind. Progress has been made in discovery of biomarkers to guide a precision medicine approach to treatment of food and drug allergy, but further validation and quantification of these biomarkers are needed to allow their translation into practice in the clinical management of allergic disease. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Causality in Europeanization Research

    DEFF Research Database (Denmark)

    Lynggaard, Kennet

    2012-01-01

    to develop discursive institutional analytical frameworks and something that comes close to the formulation of hypothesis on the effects of European Union (EU) policies and institutions on domestic change. Even if these efforts so far do not necessarily amount to substantive theories or claims of causality......Discourse analysis as a methodology is perhaps not readily associated with substantive causality claims. At the same time the study of discourses is very much the study of conceptions of causal relations among a set, or sets, of agents. Within Europeanization research we have seen endeavours......, it suggests that discourse analysis and the study of causality are by no means opposites. The study of Europeanization discourses may even be seen as an essential step in the move towards claims of causality in Europeanization research. This chapter deals with the question of how we may move from the study...

  3. The European standard series in 9 European countries, 2002/2003 - First results of the European Surveillance System on Contact Allergies

    NARCIS (Netherlands)

    Uter, W; Hegewald, J; Aberer, W; Ayala, F; Bircher, AJ; Brasch, J; Coenraads, PJ; Schuttelaar, Marielouise; Elsner, P; Fartasch, M; Mahler, V.; Fortina, AB; Frosch, PJ; Fuchs, T; Johansen, JD; Menne, T; Jolanki, R; Krecisz, B; Kiec-Swierczynska, M; Larese, F; Orton, D; Peserico, A; Rantanen, T; Schnuch, A

    Since January 2001, the European Surveillance System on Contact Allergies (ESSCA), supported by European Union funding (contract QLK4-CT-2001-00343), has started to collect patch-test data. This comprises a standardized clinical history and the patch-test results using the European standard series,

  4. Contact Allergy to Preservatives—Is the European Commission a Commendable Risk Manager?

    Directory of Open Access Journals (Sweden)

    Jakob Ferløv Schwensen

    2016-08-01

    Full Text Available Although preservatives are necessary to prevent deterioration by microbial growth in cosmetic products, daily skin contact with preserved cosmetic products may cause a preservative contact allergy. Only preservatives with sufficient pre-market risk assessment, presumably being safe for the consumer from a public health point of view, are permitted for use in cosmetic products in the European Union. Notwithstanding the efforts by the European Commission (EC to avoid epidemics of contact allergy, the former epidemic of contact allergy to methyldibromo glutaronitrile and the unprecedented epidemic of contact allergy to methylisothiazolinone show the procrastination of the European Union risk management process for cosmetic ingredients. Timely risk management is of the utmost importance to avoid rapidly increasing numbers of contact allergy to turn into full-blown epidemics. It is therefore proposed that in order to avoid future epidemics of contact allergy to preservatives, the allowed preservatives in cosmetic products should be entered onto Annex V on a time-limited basis only, and they must be re-evaluated in order to stay on Annex V.

  5. The European standard series in 9 European countries, 2002/2003 -- first results of the European Surveillance System on Contact Allergies

    DEFF Research Database (Denmark)

    Uter, W; Hegewald, J; Aberer, W

    2005-01-01

    Since January 2001, the European Surveillance System on Contact Allergies (ESSCA), supported by European Union funding (contract QLK4-CT-2001-00343), has started to collect patch-test data. This comprises a standardized clinical history and the patch-test results using the European standard series...... observed. The prevalence of contact allergy to Myroxylon pereirae resin (balsam of Peru) (5.8%) is coming close to the frequency found with the fragrance mix (6.4%). Regarding contact allergy to chromium compounds, different frequencies were noted in the 2 centres focused on occupational dermatitis (2......-marketing surveillance in the field of contact allergy, ESSCA will meet its objective of increased consumer safety across Europe....

  6. Allergy, living and learning

    DEFF Research Database (Denmark)

    Chivato, T; Valovirta, E; Dahl, R

    2012-01-01

    Allergy Living and Learning (ALL) is a European initiative designed to increase knowledge and understanding of people living with allergies in order to improve respiratory allergy care.......Allergy Living and Learning (ALL) is a European initiative designed to increase knowledge and understanding of people living with allergies in order to improve respiratory allergy care....

  7. Knowing What You Eat: Researchers Are Looking for Ways to Help People Cope with Food Allergies.

    Science.gov (United States)

    Grifantini, Kristina

    2016-01-01

    Food allergies and sensitivities have always been a public health problem but are becoming more prevalent worldwide. The U.S. Food and Drug Administration (FDA) reports that millions of Americans have allergic reactions to food each year. More than 17 million Europeans have a food allergy, and hospital admissions for severe reactions in children have risen sevenfold over the past decade, according to the European Academy of Allergy and Clinical Immunology.

  8. Research needs in allergy: an EAACI position paper, in collaboration with EFA

    Directory of Open Access Journals (Sweden)

    Papadopoulos Nikolaos G

    2012-11-01

    Full Text Available Abstract In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More disturbingly, its prevalence and impact are on the rise, a development that has been associated with environmental and lifestyle changes accompanying the continuous process of urbanization and globalization. Therefore, there is an urgent need to prioritize and concert research efforts in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21st century. The European Academy of Allergy and Clinical Immunology (EAACI is the leading professional organization in the field of allergy, promoting excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients’ Associations (EFA is a non-profit network of allergy, asthma and Chronic Obstructive Pulmonary Disorder (COPD patients’ organizations. In support of their missions, the present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels. Although allergies may involve almost every organ of the body and an array of diverse external factors act as triggers, there are several common themes that need to be prioritized in research efforts. As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. Detailed phenotyping/endotyping stands out as widely required in order to arrange or re-categorize clinical syndromes into

  9. Prevalence of fragrance contact allergy in the general population of five European countries : A cross-sectional study

    NARCIS (Netherlands)

    Diepgen, T. L.; Ofenloch, R.; Bruze, M.; Cazzaniga, S.; Coenraads, P. J.; Elsner, P.; Goncalo, M.; Svensson, A.; Naldi, L.

    2015-01-01

    Background Contact allergy to fragrances is assessed mostly in clinical populations of patients. Studies in the general population are scarce and vary in their methodology across countries. Objectives To determine the prevalence of fragrance contact allergy in the European general population and to

  10. Action Research in European perspective

    DEFF Research Database (Denmark)

    Rasmussen, Lauge Baungaard

    2004-01-01

    The article gives an overview of how different Italian and Danish contributions to action research can be viewed in an European perspective.......The article gives an overview of how different Italian and Danish contributions to action research can be viewed in an European perspective....

  11. European symposium on the awareness of allergy: report of the promotional campaign in the European Parliament (26-28 April 2016).

    Science.gov (United States)

    Muraro, A; Steelant, B; Pietikainen, S; Borrelli, D; Childers, N; Callebaut, I; Kortekaas Krohn, I; Martens, K; Pugin, B; Popescu, F-D; Vieru, M; Jutel, M; Agache, I; Hellings, P W

    2017-02-01

    From 26 to 28 of April 2016, an allergy awareness campaign was organized by the European Academy of Allergy and Clinical Immunology and the European Federation of Allergy and Airway Diseases Patients Associations in the European Parliament in Brussels, with support of the European Parliament's Interest group on Allergy and Asthma and was co-hosted by the Members of the European Parliament David Borrelli, Sirpa Pietikainen and Nessa Childers. Skin prick tests (SPTs) were performed to gain attention for the increasing prevalence of allergic airway diseases in Europe. Since more than 30% of the total European population suffers from airway allergies and asthma, reaching a higher level of awareness and elaboration of an active prevention plan is mandatory. Of the 406 individuals undergoing SPT in the European Parliament, 211 participants (52%) reported to have suffered from an allergy in the past, with allergic symptoms being present in the nose and eyes (40% and 36%, respectively), the skin (27%), lower airways (14%) and the gut (8%). Of the 381 SPT with reliable results, cutaneous hypersensitivity was found in 201 (53%) participants. Of those with positive SPT (n = 201), 70 participants (35%) were monosensitized while 131 participants (65%) were polysensitized. The positive skin reactions were found mostly for grass pollen (n = 108), followed by Dermatophagoides pteronyssinus (n = 105), Dermatophagoides farina (n = 96) and birch pollen (n = 85). Of note, 54 individuals (14% of the total tested population) without reported allergy or allergic symptoms showed a positive SPT without clinical relevance. This report summarizes the main idea and goals of the symposium: chronic airway diseases are a major and growing health problem in Europe. Therefore, a joint preventive action plan needs to be developed for a better health status of European citizens. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. European Surveillance System on Contact Allergies (ESSCA) : Results with the European baseline series, 2013/14

    NARCIS (Netherlands)

    Uter, W.; Amario-Hita, J. C.; Balato, A.; Ballmer-Weber, B.; Bauer, A.; Fortina, A. Belloni; Bircher, A.; Chowdhury, M. M. U.; Cooper, S. M.; Czarnecka-Operacz, M.; Dugonik, A.; Gallo, R.; Gimenez-Arnau, A.; Johansen, J. D.; John, S. M.; Kiec-Swierczynska, M.; Kmecl, T.; Krezcisz, B.; Filon, F. Larese; Mahler, V.; Pesonen, M.; Rustemeyer, T.; Sadowska-Przytocka, A.; Sanchez-Perez, J.; Schliemann, S.; Schuttelaar, M. L.; Simon, D.; Spiewak, R.; Valiukeviciene, S.; Weisshaar, E.; White, I. R.; Wilkinson, S. M.

    Background Contact allergy is a common condition and can severely interfere with daily life or professional activities. Due to changes in exposures, such as introduction of new substances, new products or formulations and regulatory intervention, the spectrum of contact sensitization changes.

  13. Respiratory sensitization and allergy: Current research approaches and needs

    International Nuclear Information System (INIS)

    Boverhof, Darrell R.; Billington, Richard; Gollapudi, B. Bhaskar; Hotchkiss, John A.; Krieger, Shannon M.; Poole, Alan; Wiescinski, Connie M.; Woolhiser, Michael R.

    2008-01-01

    There are currently no accepted regulatory models for assessing the potential of a substance to cause respiratory sensitization and allergy. In contrast, a number of models exist for the assessment of contact sensitization and allergic contact dermatitis (ACD). Research indicates that respiratory sensitizers may be identified through contact sensitization assays such as the local lymph node assay, although only a small subset of the compounds that yield positive results in these assays are actually respiratory sensitizers. Due to the increasing health concerns associated with occupational asthma and the impending directives on the regulation of respiratory sensitizers and allergens, an approach which can identify these compounds and distinguish them from contact sensitizers is required. This report discusses some of the important contrasts between respiratory allergy and ACD, and highlights several prominent in vivo, in vitro and in silico approaches that are being applied or could be further developed to identify compounds capable of causing respiratory allergy. Although a number of animal models have been used for researching respiratory sensitization and allergy, protocols and endpoints for these approaches are often inconsistent, costly and difficult to reproduce, thereby limiting meaningful comparisons of data between laboratories and development of a consensus approach. A number of emerging in vitro and in silico models show promise for use in the characterization of contact sensitization potential and should be further explored for their ability to identify and differentiate contact and respiratory sensitizers. Ultimately, the development of a consistent, accurate and cost-effective model will likely incorporate a number of these approaches and will require effective communication, collaboration and consensus among all stakeholders

  14. Characteristics of patients patch tested in the European Surveillance System on Contact Allergies (ESSCA) network, 2009-2012

    DEFF Research Database (Denmark)

    Uter, Wolfgang; Gefeller, Olaf; Giménez-Arnau, Ana

    2015-01-01

    from 63 530 consultations collected by 53 departments from 12 countries participating in the European Surveillance System on Contact Allergies (ESSCA) ( www.essca-dc.org) between 2009 and 2012. RESULTS: Considerable variation in the prevalence of the MOAHLFA factors between departments was found...... one department per country give valuable insights into the spectrum of contact allergy prevalence rates in that country, but are not as representative as national data pooled from several departments....

  15. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: the European Dermato-Epidemiology Network Fragrance Study

    OpenAIRE

    Rossi, M; Coenraads, PJ; Diepgen, T; Svensson, A; Elsner, P; Gonçalo, Margarida; Bruze, M; Naldi, L

    2010-01-01

    Background/Aims: Data on contact allergy to fragrances in the general population are limited. Data from allergological services suggest that the frequency of contact allergy to fragrances is increasing. The European Dermato-Epidemiology Network (EDEN) Fragrance Study aims to obtain reliable data on the prevalence of contact allergy to fragrances and other sensitizers of the European baseline series, in the general population of different geographical areas of Europe. We report the methodology...

  16. New food allergies in a European non-Mediterranean region: is Cannabis sativa to blame?

    Science.gov (United States)

    Ebo, D G; Swerts, S; Sabato, V; Hagendorens, M M; Bridts, C H; Jorens, P G; De Clerck, L S

    2013-01-01

    Allergy to fruit and vegetables exhibit geographic variation regarding the severity of symptoms and depending on the sensitization profile of the patient. These sensitization profiles and routes remain incompletely understood. Cannabis is a very popular drug and derived from Cannabis sativa, a plant containing lipid transfer proteins (LTP) also known as important allergens in plant and fruit allergies. In this study we sought to elucidate a potential connection between C. sativa allergy and plant food allergies. A case-control study involving 21 patients consulting for plant food allergies. Twelve patients were cannabis allergic and 9 had a pollen or latex allergy without cannabis allergy. Testing for cannabis IgE implied measurement of specific IgE, skin testing and basophil activation tests. Allergen component analysis was performed with a microarray technique. Plant food allergy in patients with documented cannabis allergy had more severe reactions than patients without cannabis allergy and frequently implied fruits and vegetables that are not observed in a (birch) pollen-related food syndrome. With the exception of 1 patient with cannabis allergy, all were sensitized to nonspecific (ns)-LTP. Our data suggest that illicit cannabis abuse can result in cannabis allergy with sensitization to ns-LTP. This sensitization might result in various plant-food allergies. Additional collaborative studies in different geographical areas are needed to further elucidate on this hypothesis. Copyright © 2013 S. Karger AG, Basel.

  17. The European Hematology Association Roadmap for European Hematology Research

    DEFF Research Database (Denmark)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke

    2016-01-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology...... research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness...... of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology...

  18. The European Social Survey and European research policy

    DEFF Research Database (Denmark)

    Kropp, Kristoffer

    2017-01-01

    This article analyses the history of the European Social Survey (ESS) and its relationship to changes in European research policy, using Bourdieu’s field-analytical approach. It argues that the success of the ESS relied on three interwoven processes that we can understand theoretically in terms...... of the establishment of homological structures and the formation of conjunctural alliances between the field of European social-scientific research and the field of European policy. The three interwoven processes that I depict are: first, the production of a European field of social research, connected to both...... European and national scientific institutions; second, the establishment of European Union (EU) institutions and organisations that were able to identify and link up with social researchers; and third, the formation of conjunctural alliances between the two fields (social science and EU research policy...

  19. Food Allergy Educational Needs of Pediatric Dietitians: A Survey by the Consortium of Food Allergy Research

    Science.gov (United States)

    Groetch, Marion E.; Christie, Lynn; Vargas, Perla A.; Jones, Stacie M.; Sicherer, Scott H.

    2010-01-01

    Objective: To determine pediatric dietitians' self-reported proficiency, educational needs, and preferences regarding food allergy (FA) management. Design and Setting: An Internet-based, anonymous survey was distributed to the Pediatric Nutrition Practice Group (PNPG) of the American Dietetic Association. Participants: Respondents (n = 311) were…

  20. European Research in Marine Structures

    DEFF Research Database (Denmark)

    Soares, C.Guedes; Jensen, Jørgen Juncher; Incecik, A.

    2012-01-01

    An overview is presented of the results obtained in Europe by a network with a large number of research groups in the field of Marine Structures during a period of 6 years. The European Union has funded a project aimed at improving the collaboration among European research groups specialized...... in marine structures, which has led, among other results to a number of benchmark studies organized in 6 main topical areas, namely, Methods and Tools for Loads and Load Effects, Methods and Tools for Strength Assessment, Experimental Analysis of Structures, Materials and Fabrication of Structures, Methods...... and Tools for Structural Design and Optimization and Structural Reliability, Safety and Environmental Protection. This paper presents an overview of various studies performed, which helps identifying the level of consistency and robustness of different numeric tools used in this field....

  1. European Research Reloaded : Cooperation and Integration Among Europeanized States

    NARCIS (Netherlands)

    Holzhacker, Ron; Haverland, Markus

    2006-01-01

    European integration has had an ever deepening impact on the member states. The first wave of research concerned the process of institution building and policy developments at the European Union (EU) level. The second wave, on Europeanization used the resulting integration as an explanatory factor

  2. Preventing food allergy

    DEFF Research Database (Denmark)

    de Silva, Debra; Panesar, Sukhmeet S; Thusu, Sundeep

    2013-01-01

    The European Academy of Allergy and Clinical Immunology is developing guidelines about how to prevent and manage food allergy. As part of the guidelines development process, a systematic review is planned to examine published research about the prevention of food allergy. This systematic review...... is one of seven inter-linked evidence syntheses that are being undertaken in order to provide a state-of-the-art synopsis of the current evidence base in relation to epidemiology, prevention, diagnosis and clinical management, and impact on quality of life, which will be used to inform clinical...... recommendations. The aim of this systematic review will be to assess the effectiveness of approaches for the primary prevention of food allergy....

  3. Prevalence of fragrance contact allergy in the general population of five European countries: a cross-sectional study.

    Science.gov (United States)

    Diepgen, T L; Ofenloch, R; Bruze, M; Cazzaniga, S; Coenraads, P J; Elsner, P; Goncalo, M; Svensson, Å; Naldi, L

    2015-12-01

    Contact allergy to fragrances is assessed mostly in clinical populations of patients. Studies in the general population are scarce and vary in their methodology across countries. To determine the prevalence of fragrance contact allergy in the European general population and to assess the clinical relevance of positive patch test reactions to different fragrances. In five European countries (Germany, Italy, the Netherlands, Portugal and Sweden) a random sample from the general population aged 18-74 years was drawn. In total, 12 377 subjects were interviewed in this cross-sectional study and a random sample (n = 3119) was patch tested using the TRUE Test and Finn Chamber techniques. Patch test procedures were harmonized by mandatory training before the study and monitoring during the study. The highest prevalence for contact allergy of 2·6% [95% confidence interval (CI) 2·1-3·2] was found for fragrance mix (FM) I in petrolatum, with a high content of atranol and chloratranol, followed by 1·9% (95% CI 1·5-2·4) for FM II in petrolatum. The conservatively estimated prevalence of fragrance contact allergy was 1·9% (95% CI 1·5-2·5). This is defined as the existence of a positive patch test to FM I or FM II; any of their individual materials; Myroxylon pereirae; sesquiterpene lactones or 3- and 4-hydroxyisohexyl 3-cyclohexene carboxaldehyde that show clinical relevance, defined conservatively as lifetime avoidance of scented products and an itchy skin rash lasting > 3 days in a lifetime. Using the reported lifetime prevalence of any contact dermatitis instead of the lifetime prevalence of any itchy skin rash, the prevalence is 0·8% (95% CI 0·5-1·2). The prevalence rates of contact allergy to fragrances in women are about twice those in men. This study helps to identify targets for prevention of fragrance allergy. © 2015 British Association of Dermatologists.

  4. Design and Feasibility of an International Study Assessing the Prevalence of Contact Allergy to Fragrances in the General Population : The European Dermato-Epidemiology Network Fragrance Study

    NARCIS (Netherlands)

    Rossi, Marta; Coenraads, Pieter-Jan; Diepgen, Thomas; Svensson, Ake; Elsner, Peter; Goncalo, Margarida; Bruze, Magnus; Naldi, Luigi

    2010-01-01

    Background/Aims: Data on contact allergy to fragrances in the general population are limited. Data from allergological services suggest that the frequency of contact allergy to fragrances is increasing. The European Dermato-Epidemiology Network (EDEN) Fragrance Study aims to obtain reliable data on

  5. The EuroPrevall birth cohort study on food allergy: baseline characteristics of 12,000 newborns and their families from nine European countries

    NARCIS (Netherlands)

    McBride, D.; Keil, T.; Grabenhenrich, L.; Dubakiene, R.; Drasutiene, G.; Fiocchi, A.; Dahdah, L.; Sprikkelman, A. B.; Schoemaker, A. A.; Roberts, G.; Grimshaw, K.; Kowalski, M. L.; Stanczyk-Przyluska, A.; Sigurdardottir, S.; Clausen, M.; Papadopoulos, N. G.; Mitsias, D.; Rosenfeld, L.; Reche, M.; Pascual, C.; Reich, A.; Hourihane, J.; Wahn, U.; Mills, E. N. C.; Mackie, A.; Beyer, K.

    2012-01-01

    It is unclear why some children develop food allergy. The EuroPrevall birth cohort was established to examine regional differences in the prevalence and risk factors of food allergy in European children using gold-standard diagnostic criteria. The aim of this report was to describe pre-, post-natal

  6. popscience - European Researchers Night 2014

    CERN Multimedia

    Jeanneret, Guillaume

    2014-01-01

    Vendredi 26 septembre 2014, le CERN célèbrera la Nuit européenne des chercheurs à Genève et à St-Genis-Pouilly. Le thème de l’édition 2014 est inspiré d’Andy Warhol : « Pop science is for everyone ». On Friday 26 September 2014, CERN will be celebrating European Researchers' Night at three venues in Geneva and St. Genis-Pouilly. Inspired by Andy Warhol, this year's theme is “Pop science is for everyone”.

  7. Multi-morbidities of allergic rhinitis in adults: European Academy of Allergy and Clinical Immunology Task Force Report.

    Science.gov (United States)

    Cingi, C; Gevaert, P; Mösges, R; Rondon, C; Hox, V; Rudenko, M; Muluk, N B; Scadding, G; Manole, F; Hupin, C; Fokkens, W J; Akdis, C; Bachert, C; Demoly, P; Mullol, J; Muraro, A; Papadopoulos, N; Pawankar, R; Rombaux, P; Toskala, E; Kalogjera, L; Prokopakis, E; Hellings, P W; Bousquet, J

    2017-01-01

    This report has been prepared by the European Academy of Allergy and Clinical Immunology Task Force on Allergic Rhinitis (AR) comorbidities. The aim of this multidisciplinary European consensus document is to highlight the role of multimorbidities in the definition, classification, mechanisms, recommendations for diagnosis and treatment of AR, and to define the needs in this neglected area by a literature review. AR is a systemic allergic disease and is generally associated with numerous multi-morbid disorders, including asthma, eczema, food allergies, eosinophilic oesophagitis (EoE), conjunctivitis, chronic middle ear effusions, rhinosinusitis, adenoid hypertrophy, olfaction disorders, obstructive sleep apnea, disordered sleep and consequent behavioural and educational effects. This report provides up-to-date usable information to: (1) improve the knowledge and skills of allergists, so as to ultimately improve the overall quality of patient care; (2) to increase interest in this area; and (3) to present a unique contribution to the field of upper inflammatory disease.

  8. European perspectives on security research

    CERN Document Server

    2011-01-01

    Europe’s networked societies of today are shaped by a growing interconnection in almost all areas of life. The complexity of our infrastructures and the concurrent accessibility to means of destruction by terrorist groups and individual perpetrators call for innovative security solutions. However, such evolving innovations inevitably raise fundamental questions of concern in our societies. How do we balance the imperatives of securing our citizens and infrastructures on the one hand, and of protecting of our sacredly held civil liberties on the other? The topical network ‘Safety and Security’ of acatech – the German Academy of Science and Engineering – invited experts from the science academies of various European countries to share their perspectives on security research and the aspect of safety during a two-day workshop hosted by the Fraunhofer Institute for High-Speed Dynamics, Ernst-Mach-Institut in March 2010. This publication is a compilation of contributions made during the workshop.

  9. Incorporating a gender dimension in food allergy research: a review

    NARCIS (Netherlands)

    DunnGalvin, A.; Hourihane, J.O.B.; Frewer, L.J.; Knibb, R.C.; Oude Elberink, J.N.G.; Klinge, I.

    2006-01-01

    Sex and gender are the major determinants of health and disease in both men and women. The aim of this review paper was to examine differences in gender and sex in relation to the prevalence and effects of food allergy. There are still major gaps in our knowledge about the kinds of processes which

  10. EPERC: The European Pressure Equipment Research Council

    International Nuclear Information System (INIS)

    Darlaston, J.; McAllister, S.

    1998-01-01

    The European Pressure Equipment Research Council (EPERC) is a European Network of industries, research laboratories, inspection bodies and governmental institutions set up to foster co-operative research for the greater benefit of the European industry. The concept of a European Research Council originated at the PVRC meeting in Cannes in 1989 and since this time volunteers from the industry, research laboratories and of the European Commission Joint Research Centre, Petten have worked together to create a Statute for EPERC. In the context of the pressure equipment industry, the creation of EPERC is extremely pertinent, since in the near future, a Council directive on pressure equipment will replace the existing national regulations. In parallel to this, work is in progress for the elaboration of European Standards. It is useful to recall that ''Harmonised Standards'' will be the privileged means of complying with the Essential Safety Requirements of the directive. (author)

  11. The microbiome in allergic disease: Current understanding and future opportunities—2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology

    Science.gov (United States)

    Huang, Yvonne J.; Marsland, Benjamin J.; Bunyavanich, Supinda; O’Mahony, Liam; Leung, Donald Y. M.; Muraro, Antonella; Fleisher, Thomas A.

    2018-01-01

    PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both. PMID:28257972

  12. The microbiome in allergic disease: Current understanding and future opportunities-2017 PRACTALL document of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology.

    Science.gov (United States)

    Huang, Yvonne J; Marsland, Benjamin J; Bunyavanich, Supinda; O'Mahony, Liam; Leung, Donald Y M; Muraro, Antonella; Fleisher, Thomas A

    2017-04-01

    PRACTALL is a joint initiative of the American Academy of Allergy, Asthma & Immunology and the European Academy of Allergy and Clinical Immunology to provide shared evidence-based recommendations on cutting-edge topics in the field of allergy and immunology. PRACTALL 2017 is focused on what has been established regarding the role of the microbiome in patients with asthma, atopic dermatitis, and food allergy. This is complemented by outlining important knowledge gaps regarding its role in allergic disease and delineating strategies necessary to fill these gaps. In addition, a review of progress in approaches used to manipulate the microbiome will be addressed, identifying what has and has not worked to serve as a baseline for future directions to intervene in allergic disease development, progression, or both. Copyright © 2017. Published by Elsevier Inc.

  13. EAACI Food Allergy and Anaphylaxis Guidelines. Food allergy health-related quality of life measures.

    Science.gov (United States)

    Muraro, A; Dubois, A E J; DunnGalvin, A; Hourihane, J O'B; de Jong, N W; Meyer, R; Panesar, S S; Roberts, G; Salvilla, S; Sheikh, A; Worth, A; Flokstra-de Blok, B M J

    2014-07-01

    Instruments have been developed and validated for the measurement of health-related quality of life in patients with food allergy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group. It draws on a systematic review of the literature on quality of life instruments for food allergy and the Appraisal of Guidelines for Research & Evaluation (AGREE II) guideline development process. Guidance is provided on the use of such instruments in research, and the current limitations of their use in clinical practice are described. Gaps in current knowledge as well as areas of future interest are also discussed. This document is relevant to healthcare workers dealing with food-allergic patients, scientists engaging in food allergy research and policy makers involved in regulatory aspects concerning food allergy and safety. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Penicillin allergy: optimizing diagnostic protocols, public health implications, and future research needs.

    Science.gov (United States)

    Macy, Eric

    2015-08-01

    Unverified penicillin allergy is being increasingly recognized as a public health concern. The ideal protocol for verifying true clinically significant IgE-mediated penicillin allergy needs to use only commercially available materials, be well tolerated and easy to perform in both the inpatient and outpatient settings, and minimize false-positive determinations. This review concentrates on articles published in 2013 and 2014 that present new data relating to the diagnosis and management of penicillin allergy. Penicillin allergy can be safely evaluated at this time, in patients with an appropriate clinical history of penicillin allergy, using only penicilloyl-poly-lysine and native penicillin G as skin test reagents, if an oral challenge with amoxicillin 250 mg, followed by 1 h of observation, is given to all skin test negative individuals. Millions of individuals falsely labeled with penicillin allergy need to be evaluated to safely allow them to use penicillin-class antibiotics and avoid morbidity associated with penicillin avoidance. Further research is needed to determine optimal protocol(s). There will still be a 1-2% rate of adverse reactions reported with all future therapeutic penicillin-class antibiotic use, even with optimal methods used to determine acute penicillin tolerance. Only a small minority of these new reactions will be IgE-mediated.

  15. New ideas in asthma and allergy research: creating a multidisciplinary graduate school

    Science.gov (United States)

    Björkstén, Bengt; Graninger, Göran; Ekman, Gunilla Jacobsson

    2003-01-01

    The spring term of 2001 saw the start of a new, unique graduate research training program at the Centre for Allergy Research at the Karolinska Institutet in Stockholm, Sweden. The program was created to bridge the gaps between basic, clinical, social, and behavioral sciences and to establish a global approach to the study of asthma and allergy. A reflection, two years on, discusses the strategies that are key to this model’s success and the challenges in introducing a multidisciplinary research program. PMID:12975463

  16. The newsletter 'European Research in Radiological Sciences'

    International Nuclear Information System (INIS)

    Pihet, P.; D'Errico, F.; Doerr, W.; Gruenberger, M.; Schofield, P.

    2004-01-01

    The newsletter 'European Research in Radiological Sciences' is jointly published by the European Late Effects Project Group and the European Radiation Dosimetry Group to disseminate information about research projects and activities carried out under the EURATOM Framework Programme. Since May 2003, the Newsletter is operated interactively from the Internet. The new site uses a dedicated database that automatically generates HTML pages. This system developed at the Univ. of Cambridge provides an innovative approach to improve the dissemination of project information. (authors)

  17. Meta-analysis of determinants for pet ownership in 12 European birth cohorts on asthma and allergies: a GA2LEN initiative

    DEFF Research Database (Denmark)

    Eller, E; Roll, S; Chen, C-M

    2008-01-01

    BACKGROUND: Studies on pet ownership as a risk or protective factor for asthma and allergy show inconsistent results. This may be on account of insufficient adjustment of confounding factors. AIM: The objective of this study was to describe determinants of cat and dog ownership in European families...... with and without allergies. METHODS: Within the EU-funded network of excellence GA(2)LEN, we performed meta-analyses with data from 12 ongoing European birth cohort studies on asthma and allergy. Each of the birth cohort studies enrolled between 485 and 4089 children. Pet ownership, allergic status (asthma......, allergic rhinitis, eczema) of parents and siblings, parental education, access to ground floor, and number of people living at home were assessed by questionnaires. RESULTS: Among the 25 056 families from seven European countries cats (14.9%) were more common than dogs (12.0%). Allergic family history...

  18. Understanding the infrastructure of European Research Infrastructures

    DEFF Research Database (Denmark)

    Lindstrøm, Maria Duclos; Kropp, Kristoffer

    2017-01-01

    European Research Infrastructure Consortia (ERIC) are a new form of legal and financial framework for the establishment and operation of research infrastructures in Europe. Despite their scope, ambition, and novelty, the topic has received limited scholarly attention. This article analyses one ER....... It is also a promising theoretical framework for addressing the relationship between the ERIC construct and the large diversity of European Research Infrastructures.......European Research Infrastructure Consortia (ERIC) are a new form of legal and financial framework for the establishment and operation of research infrastructures in Europe. Despite their scope, ambition, and novelty, the topic has received limited scholarly attention. This article analyses one ERIC...... became an ERIC using the Bowker and Star’s sociology of infrastructures. We conclude that focusing on ERICs as a European standard for organising and funding research collaboration gives new insights into the problems of membership, durability, and standardisation faced by research infrastructures...

  19. Food Allergy Education for School Nurses: A Needs Assessment Survey by the Consortium of Food Allergy Research

    Science.gov (United States)

    Carlisle, Suzanna K.; Vargas, Perla A.; Noone, Sally; Steele, Pam; Sicherer, Scott H.; Burks, A. Wesley; Jones, Stacie M.

    2010-01-01

    Food allergy is increasing in school-age children. School nurses are a primary health care resource for children with food allergy and must be prepared to manage allergen avoidance and respond in the event of an allergic reaction. An anonymous survey was administered to school nurses attending their association meetings to determine their…

  20. Blood fatty acid composition in relation to allergy in children aged 2-9 years: results from the European IDEFICS study.

    Science.gov (United States)

    Mikkelsen, A; Galli, C; Eiben, G; Ahrens, W; Iacoviello, L; Molnár, D; Pala, V; Risé, P; Rodriguez, G; Russo, P; Tornaritis, M; Veidebaum, T; Vyncke, K; Wolters, M; Mehlig, K

    2017-01-01

    Blood polyunsaturated fatty acids (PUFA) are involved in allergy development, but the etiological role of n-6 and n-3 PUFA is still controversial. A European multicenter study of children (IDEFICS) provided the opportunity to explore the cross-sectional association between fatty acids (FA) and allergy. Blood FA levels were measured in 2600 children aged 2-9 years and were recorded as the percentage of weight of all FA detected. Logistic regression of allergy status on FA components was adjusted for age, sex, country, body mass index, family history of allergic disease, breast-feeding, and number of siblings. The results were given as odds ratios (OR) for current vs no allergy ever and an increase in FA by 1 s.d. Overall, higher proportions of n-6 PUFA were associated with higher odds of allergy (OR=1.21 (1.05, 1.40)). Monounsaturated FA (MUFA) were associated with reduced risk for allergy (OR=0.75 (0.65, 0.87)), whereas saturated FA did not differ by allergy status. The strongest associations were observed in children children younger than 4 years might help to understand the nature of early onset of atopic disease.

  1. Radiation research: the European programme

    International Nuclear Information System (INIS)

    Gerber, G.B.

    1985-01-01

    A summary is given of an oral presentation on the European Community's Radiation Protection Programme. Aspects of the programme discussed included its development which began 25 years ago, the administrative structure, the financial success and the funding for 1985/89. Finally, the six subject sectors of the programme were discussed, giving a broad description of where the emphases had been laid and how each sector had fared. (U.K.)

  2. Consensus document on European brain research

    DEFF Research Database (Denmark)

    Di Luca, Monica; Baker, Mary; Corradetti, Renato

    2011-01-01

    will increase exponentially in the years to come due to ageing of the European population, it is necessary to act now in order to curb this increase and possibly reverse the trend. Thus, establishing a strong European platform supporting basic and clinical research in neuroscience is needed to confront...... version. Multinational and multidisciplinary teams have once again come together to express their views, not only on the current strengths in European research, but also on what needs to be done in priority, hoping that this update will inspire policy makers and stakeholders in directing funding...

  3. West European magnetic confinement fusion research

    International Nuclear Information System (INIS)

    McKenney, B.L.; McGrain, M.; Hogan, J.T.; Porkolab, M.; Thomassen, K.I.

    1990-01-01

    This report presents a technical assessment and review of the West European program in magnetic confinement fusion by a panel of US scientists and engineers active in fusion research. Findings are based on the scientific and technical literature, on laboratory reports and preprints, and on the personal experiences and collaborations of the panel members. Concerned primarily with developments during the past 10 years, from 1979 to 1989, the report assesses West European fusion research in seven technical areas: tokamak experiments; magnetic confinement technology and engineering; fusion nuclear technology; alternate concepts; theory; fusion computations; and program organization. The main conclusion emerging from the analysis is that West European fusion research has attained a position of leadership in the international fusion program. This distinction reflects in large measure the remarkable achievements of the Joint European Torus (JET). However, West European fusion prominence extends beyond tokamak experimental physics: the program has demonstrated a breadth of skill in fusion science and technology that is not excelled in the international effort. It is expected that the West European primacy in central areas of confinement physics will be maintained or even increased during the early 1990s. The program's maturity and commitment kindle expectations of dramatic West European advances toward the fusion energy goal. For example, achievement of fusion breakeven is expected first in JET, before 1995

  4. Patch test results with fragrance markers of the baseline series - analysis of the European Surveillance System on Contact Allergies (ESSCA) network 2009-2012

    NARCIS (Netherlands)

    Frosch, Peter J.; Johansen, Jeanne Duus; Schuttelaar, Marie-Louise A.; Silvestre, Juan F.; Sanchez-Perez, Javier; Weisshaar, Elke; Uter, Wolfgang

    Background. Contact allergy to fragrances is common, and impairs quality of life, particularly in young women. Objective. To provide current results on the prevalences of sensitization to fragrance allergens used as markers in the baseline series of most European countries. Methods. Data of patients

  5. Patch test results with fragrance markers of the baseline series - analysis of the European Surveillance System on Contact Allergies (ESSCA) network 2009-2012

    DEFF Research Database (Denmark)

    Frosch, Peter J; Duus Johansen, Jeanne; Schuttelaar, Marie-Louise A

    2015-01-01

    BACKGROUND: Contact allergy to fragrances is common, and impairs quality of life, particularly in young women. OBJECTIVE: To provide current results on the prevalences of sensitization to fragrance allergens used as markers in the baseline series of most European countries. METHODS: Data of patie......BACKGROUND: Contact allergy to fragrances is common, and impairs quality of life, particularly in young women. OBJECTIVE: To provide current results on the prevalences of sensitization to fragrance allergens used as markers in the baseline series of most European countries. METHODS: Data...... of patients consecutively patch tested between 2009 and 2012 in 12 European countries with fragrance allergens contained in the baseline series were collected by the European Surveillance System on Contact Allergies network and descriptively analysed. Four departments used the TRUE Test(®) system. RESULTS......: Contact allergy to fragrances is common throughout Europe, with regional variation probably being explained by patch test technique, and differences in exposure and referral patterns. The current basic markers of fragrance sensitivity in the baseline series should be supplemented with additional fragrance...

  6. Body mass index trajectory classes and incident asthma in childhood: results from 8 European Birth Cohorts--a Global Allergy and Asthma European Network initiative.

    Science.gov (United States)

    Rzehak, Peter; Wijga, Alet H; Keil, Thomas; Eller, Esben; Bindslev-Jensen, Carsten; Smit, Henriette A; Weyler, Joost; Dom, Sandra; Sunyer, Jordi; Mendez, Michelle; Torrent, Maties; Vall, Oriol; Bauer, Carl-Peter; Berdel, Dietrich; Schaaf, Beate; Chen, Chih-Mei; Bergström, Anna; Fantini, Maria P; Mommers, Monique; Wahn, Ulrich; Lau, Susanne; Heinrich, Joachim

    2013-06-01

    The causal link between body mass index (BMI) or obesity and asthma in children is still being debated. Analyses of large longitudinal studies with a sufficient number of incident cases and in which the time-dependent processes of both excess weight and asthma development can be validly analyzed are lacking. We sought to investigate whether the course of BMI predicts incident asthma in childhood. Data from 12,050 subjects of 8 European birth cohorts on asthma and allergies were combined. BMI and doctor-diagnosed asthma were modeled during the first 6 years of life with latent growth mixture modeling and discrete time hazard models. Subpopulations of children were identified with similar standardized BMI trajectories according to age- and sex-specific "World Health Organization (WHO) child growth standards" and "WHO growth standards for school aged children and adolescents" for children up to age 5 years and older than 5 years, respectively (BMI-SDS). These types of growth profiles were analyzed as predictors for incident asthma. Children with a rapid BMI-SDS gain in the first 2 years of life had a higher risk for incident asthma up to age 6 years than children with a less pronounced weight gain slope in early childhood. The hazard ratio was 1.3 (95% CI, 1.1-1.5) after adjustment for birth weight, weight-for-length at birth, gestational age, sex, maternal smoking in pregnancy, breast-feeding, and family history of asthma or allergies. A rapid BMI gain at 2 to 6 years of age in addition to rapid gain in the first 2 years of life did not significantly enhance the risk of asthma. Rapid growth in BMI during the first 2 years of life increases the risk of asthma up to age 6 years. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  7. Research Data Services in European Academic Research Libraries

    OpenAIRE

    Tenopir, Carol; Talja, Sanna; Horstmann, Wolfram; Late, Elina; Hughes, Dane; Pollock, Danielle; Schmidt, Birgit; Baird, Lynn; Sandusky, Robert J.; Allard, Suzie

    2017-01-01

    Research data is an essential part of the scholarly record, and management of research data is increasingly seen as an important role for academic libraries. This article presents the results of a survey of directors of the Association of European Research Libraries (LIBER) academic member libraries to discover what types of research data services (RDS) are being offered by European academic research libraries and what services are planned for the future. Overall, the survey found that librar...

  8. European research priorities for intracerebral haemorrhage

    DEFF Research Database (Denmark)

    Steiner, Thorsten; Petersson, Jesper; Al-Shahi Salman, Rustam

    2011-01-01

    and disability. The European Research Network on Intracerebral Haemorrhage EURONICH is a multidisciplinary academic research collaboration that has been established to define current research priorities and to conduct large clinical studies on all aspects of ICH........ No standardised diagnostic workup for the detection of the various underlying causes of ICH currently exists, and the evidence for medical or surgical therapeutic interventions remains limited. A dedicated European research programme for ICH is needed to identify ways to reduce the burden of ICH-related death...

  9. Physical Allergy

    Science.gov (United States)

    ... Autologous Stem Cell Transplant Additional Content Medical News Physical Allergy By Peter J. Delves, PhD, Professor of ... Disorders Exercise-Induced Allergic Reactions Food Allergy Mastocytosis Physical Allergy Seasonal Allergies Year-Round Allergies A physical ...

  10. Changing European Governance, Changing Research and Innovation

    DEFF Research Database (Denmark)

    Borrás, Susana

    This chapter examines two fundamental dimensions of the changing European governance, namely the coordination of national policies and the changes in membership (accession of Central and Eastern European Countries in the mid-2000, and of Brexit in late 2010s). In particular this chapter looks...... at these changes from the perspective of their effects, in an attempt to give account of what European integration means in the context of coordinating national research policies, and in the context of changes of EU membership. Hence, the paper asks the question, what are the coordination and membership effects...

  11. Nuclear safety research at the European Commission's Joint Research Centre

    International Nuclear Information System (INIS)

    Toerroenen, K.

    2003-01-01

    Nuclear power plants currently generate some 35 % of electricity used in the European Union and applicant countries. Nuclear safety will therefore remain a priority for the EU, particularly in view of enlargement, the need to monitor ageing nuclear installations and the licencing of advanced new reactor systems. The European Commission's Joint Research Centre (JRC), with its long involvement and recognised competence in nuclear safety related activities, provides direct support to the European Commission services responsible for nuclear safety and civil protection. (author)

  12. [Allergy to cosmetics. I. Fragrances].

    Science.gov (United States)

    Kieć-Swierczyńska, Marta; Krecisz, Beata; Swierczyńska-Machura, Dominika

    2004-01-01

    The authors report current information on allergy to aromatic agents present in cosmetics and products of household chemistry. In the perfume industry, about 3000 aromas are used. Single products may contain from 10 to 300 compounds. The problem of difficulties encountered in the diagnosis of hypersensitivity to odors is addressed. The mixture of 8 such products used in diagnostic screening is able to detect allergy only in about 30% of patients who do not tolerate cosmetics. Changing frequency of allergy to individual aromas is discussed. It has been now observed that cinnamon products are less allergic than chemical compounds present in oak moss. Since the 1990s of the last century, allergy to a synthetic aromatic agent, Lyral is the subject of interest in many research centers involved in studies of contact allergy. Half the cosmetics present in European markets, especially deodorants, after shave cosmetics, hand and body lotions contain this agent. It induces positive reactions in about 10% of patients allergic to aromatic agents. Detection of allergy to Lyral is difficult as it is not included in the set of commercial allergens used to diagnose hypersensitivity to aromatic agents.

  13. Clinical update on contact allergy

    DEFF Research Database (Denmark)

    Uter, Wolfgang; Johansen, Jeanne Duus; Orton, David I

    2005-01-01

    PURPOSE OF REVIEW: The aim of this article is to review recent findings in contact allergy, regarding clinical research. RECENT FINDINGS: The biocide methyldibromo glutaronitrile was identified to be an important sensitizer. Subsequently, it was banned from leave-on cosmetics in the European Union...... a classification of newly introduced chemicals; increasingly, the local lymph node assay is supplementing and potentially replacing the guinea pig maximization test. Recent advances in occupational contact allergy include, for example, some attempts to improve diagnostics for epoxy resin and other plastic, glue...

  14. Food allergy - science and policy needs - The UK Food Standards Agency Research Programme

    International Nuclear Information System (INIS)

    Buck, Joelle; Hattersley, Sue; Kimber, Ian

    2010-01-01

    Food allergy is a significant health issue in the UK, affecting between 1 and 2% of adults and 5 and 8% of children. The UK Food Standards Agency seeks to ensure the safety of food allergic consumers by providing them with information and guidance on food choices. Since 1995, with the aim of addressing important policy issues and improving the quality of the support and guidance available for food allergic consumers, the Agency (and before that the Ministry of Agriculture, Fisheries and Food), has had a programme of research dedicated to investigating the causes and mechanisms of food allergy and delivering benefits for UK consumers. In this paper, we outline some of the major scientific challenges that the programme has sought to address. We reflect on how the findings have been used as a basis for the development of sound, evidence-based policy and advice for UK consumers, and the current direction of research being supported by the programme.

  15. European research priorities for intracerebral haemorrhage

    DEFF Research Database (Denmark)

    Steiner, Thorsten; Petersson, Jesper; Al-Shahi Salman, Rustam

    2011-01-01

    Over 2 million people are affected by intracerebral haemorrhage (ICH) worldwide every year, one third of them dying within 1 month, and many survivors being left with permanent disability. Unlike most other stroke types, the incidence, morbidity and mortality of ICH have not declined over time...... and disability. The European Research Network on Intracerebral Haemorrhage EURONICH is a multidisciplinary academic research collaboration that has been established to define current research priorities and to conduct large clinical studies on all aspects of ICH....

  16. European commission research activities on iodine

    International Nuclear Information System (INIS)

    Loggia, E. della

    1996-01-01

    The research on iodine, as on other important fission products which would be released during a severe accident, carried out directly or organized by the European Commission stems from the Euratom Treaty, namely from Chapter III of the treaty which deals with the protection of the health of the population against radiations and from Chapter I which deals with research. In this paper we do not consider the Commission radiological protection programme: we limit ourselves to the presentation of the research carried out on Iodine as part of the most recent source term studies within the framework Programmes as are called the research programme of the European Commission, usually valid for a 4 year periods. The research activities are carried out by the European Commission either directly through the Joint Research Centres (JRC) or indirectly through collaboration with research organizations of Member States. Concerning the iodine research carried out as Direct Action in the Joint Research Centres, are mentioned here the most relevant activities carried out in this field at the JRC of Ispra and Karlsruhe (TUI). As Indirect Action, we present here the results of some studies allocated by the European Commission to experts of research organizations of Member Countries, followed by a short description of the main results achieved by the Reinforced Concerted Action, within the III Framework Programme (1992-1995). At the end of the paper are described the research on iodine being carried out or proposed within the IV Framework Programme (1995-1998). Mention is also done of the Commission participation, relevant in terms of financial and human efforts, to the PHEBUS FP Project. (author) refs

  17. European commission research activities on iodine

    Energy Technology Data Exchange (ETDEWEB)

    Loggia, E della [European Commission, Brussels (Belgium)

    1996-12-01

    The research on iodine, as on other important fission products which would be released during a severe accident, carried out directly or organized by the European Commission stems from the Euratom Treaty, namely from Chapter III of the treaty which deals with the protection of the health of the population against radiations and from Chapter I which deals with research. In this paper we do not consider the Commission radiological protection programme: we limit ourselves to the presentation of the research carried out on Iodine as part of the most recent source term studies within the framework Programmes as are called the research programme of the European Commission, usually valid for a 4 year periods. The research activities are carried out by the European Commission either directly through the Joint Research Centres (JRC) or indirectly through collaboration with research organizations of Member States. Concerning the iodine research carried out as Direct Action in the Joint Research Centres, are mentioned here the most relevant activities carried out in this field at the JRC of Ispra and Karlsruhe (TUI). As Indirect Action, we present here the results of some studies allocated by the European Commission to experts of research organizations of Member Countries, followed by a short description of the main results achieved by the Reinforced Concerted Action, within the III Framework Programme (1992-1995). At the end of the paper are described the research on iodine being carried out or proposed within the IV Framework Programme (1995-1998). Mention is also done of the Commission participation, relevant in terms of financial and human efforts, to the PHEBUS FP Project. (author) refs.

  18. European Research towards Future Wireless Communications

    DEFF Research Database (Denmark)

    Frederiksen, Flemming Bjerge; Prasad, Ramjee; Pedersen, Gert Frølund

    2005-01-01

    This paper presents an overview of four on-going European research projects in the field of mobile and wireless communications leading to the next generations of wireless communications. The projects started in 2004. They investigate requirements and definition of access technology, network...

  19. European Birth Cohorts for Environmental Health Research

    Czech Academy of Sciences Publication Activity Database

    Vrijheid, M.; Casas, M.; Bergström, A.; Carmichael, A.; Cordier, S.; Eggesbø, M.; Eller, E.; Fantini, M. P.; Fernández, M. F.; Fernández-Somoano, A.; Gehring, U.; Grazuleviciene, R.; Hohmann, C.; Karvonen, A. M.; Keil, T.; Kogevinas, M.; Koppen, G.; Krämer, U.; Kuehni, C. E.; Magnus, P.; Majewska, R.; Andersen, A. M. N.; Patelarou, E.; Petersen, M. S.; Pierik, F. H.; Polanska, K.; Porta, D.; Richiardi, L.; Santos, A. C.; Slama, R.; Šrám, Radim; Thijs, C.; Tischer, C.; Toft, G.; Trnovec, T.; Vandentorren, S.; Vrijkotte, T. G. M.; Wilhelm, M.; Wright, J.; Nieuwenhuijsen, M.

    2012-01-01

    Roč. 120, č. 1 (2012), s. 29-37 ISSN 0091-6765 Institutional research plan: CEZ:AV0Z50390703 Keywords : environment pollution * child health * European birth cohorts Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 7.260, year: 2012

  20. The European Holocaust Research Infrastructure Portal

    NARCIS (Netherlands)

    Blanke, Tobias; Bryant, Michael; Frankl, Michael; Kristel, Conny; Speck, Reto; Daelen, Veerle Vanden; van Horik, M.P.M.

    2016-01-01

    Over the course of the last century there have been significant changes in the practices of archives driven by the massive increase in the volume of records for archiving, a larger and more diverse user base and the digital turn. This paper analyses work undertaken by the European Holocaust Research

  1. Research Methods in European Union Studies

    DEFF Research Database (Denmark)

    Lynggaard, Kennet; Manners, Ian; Löfgren, Karl

    Research on the European Union over the past few years has been strongly implicated in the crises that currently grip Europe with a failure to ask the pertinent questions as well as a perceived weakness in the methods and evidence used by researchers providing the basis for these allegations....... This volume moves the study of EU research strategies beyond the dichotomies of the past towards a new agenda for research on Europe through a rich diversity of problem-solving based research. This new agenda acknowledges the weaknesses of the past and moves beyond them towards greater openness and awareness...

  2. Lymphocyte-based model systems for allergy research: a historic overview.

    Science.gov (United States)

    Neunkirchner, Alina; Schmetterer, Klaus G; Pickl, Winfried F

    2014-01-01

    During the last decades, a multitude of studies applying distinct in vitro and in vivo model systems have contributed greatly to our better understanding of the initiation and regulation of inflammatory processes leading to allergic diseases. Over the years, it has become evident that among lymphocytes, not only IgE-producing B cells and allergy-orchestrating CD4(+) helper cells but also cytotoxic CD8(+) T cells, γδ-T cells and innate lymphoid cells, as well as regulatory lymphocytes, might critically shape the immune response towards usually innocuous allergens. In this review, we provide a historic overview of pioneering work leading to the establishment of important lymphocyte-based model systems for allergy research. Moreover, we contrast the original findings with our currently more refined knowledge to appreciate the actual validity of the respective models and to reassess the conclusions obtained from them. Conflicting studies and interpretations are identified and discussed. The tables are intended to provide an easy overview of the field not only for scientists newly entering the field but also for the broader readership interested in updating their knowledge. Along those lines, herein we discuss in vitro and in vivo approaches to the investigation of lymphocyte effector cell activation, polarization and regulation, and describe depletion and adoptive transfer models along with gene knockout and transgenic (tg) methodologies. In addition, novel attempts to establish humanized T cell antigen receptor tg mouse models for allergy research are described and discussed. © 2014 S. Karger AG, Basel.

  3. Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology.

    Science.gov (United States)

    Muraro, Antonella; Lemanske, Robert F; Hellings, Peter W; Akdis, Cezmi A; Bieber, Thomas; Casale, Thomas B; Jutel, Marek; Ong, Peck Y; Poulsen, Lars K; Schmid-Grendelmeier, Peter; Simon, Hans-Uwe; Seys, Sven F; Agache, Ioana

    2016-05-01

    In this consensus document we summarize the current knowledge on major asthma, rhinitis, and atopic dermatitis endotypes under the auspices of the PRACTALL collaboration platform. PRACTALL is an initiative of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology aiming to harmonize the European and American approaches to best allergy practice and science. Precision medicine is of broad relevance for the management of asthma, rhinitis, and atopic dermatitis in the context of a better selection of treatment responders, risk prediction, and design of disease-modifying strategies. Progress has been made in profiling the type 2 immune response-driven asthma. The endotype driven approach for non-type 2 immune response asthma, rhinitis, and atopic dermatitis is lagging behind. Validation and qualification of biomarkers are needed to facilitate their translation into pathway-specific diagnostic tests. Wide consensus between academia, governmental regulators, and industry for further development and application of precision medicine in management of allergic diseases is of utmost importance. Improved knowledge of disease pathogenesis together with defining validated and qualified biomarkers are key approaches to precision medicine. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  4. The European Hematology Association Roadmap for European Hematology Research : A consensus document

    NARCIS (Netherlands)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology

  5. Consensus document on European brain research

    DEFF Research Database (Denmark)

    Di Luca, Monica; Baker, Mary; Corradetti, Renato

    2011-01-01

    Psychiatric and neurological diseases combined represent a considerable social and economic burden in Europe. A recent study conducted by the European Brain Council (EBC) quantified the 'cost and burden' of major brain diseases in Europe, amounting to €386bn per year. Considering that these costs...... version. Multinational and multidisciplinary teams have once again come together to express their views, not only on the current strengths in European research, but also on what needs to be done in priority, hoping that this update will inspire policy makers and stakeholders in directing funding...

  6. Design and feasibility of an international study assessing the prevalence of contact allergy to fragrances in the general population: the European Dermato-Epidemiology Network Fragrance Study.

    Science.gov (United States)

    Rossi, Marta; Coenraads, Pieter-Jan; Diepgen, Thomas; Svensson, Åke; Elsner, Peter; Gonçalo, Margarida; Bruze, Magnus; Naldi, Luigi

    2010-01-01

    Data on contact allergy to fragrances in the general population are limited. Data from allergological services suggest that the frequency of contact allergy to fragrances is increasing. The European Dermato-Epidemiology Network (EDEN) Fragrance Study aims to obtain reliable data on the prevalence of contact allergy to fragrances and other sensitizers of the European baseline series, in the general population of different geographical areas of Europe. We report the methodology and the reliability of instruments adopted and discuss the feasibility based on a pilot phase. Descriptive epidemiology survey. A random sample from the general population is selected and interviewed, and is offered patch testing in a randomized way. We specifically enquire about any skin rash reported during the previous year, and any history of reactions to products that may contain the sensitizer and/or a history of avoidance of the same products. Patch test data are linked to the questionnaire information to define clinical relevance. The questionnaire showed high test-retest reliability in 94 individuals. Patch test reading also showed a high level of interrater reliability. During the pilot phase, a total of 589 participants were recruited. The EDEN Fragrance Study is feasible and able to provide useful data on fragrance allergy.

  7. The European structural integrity research programme

    International Nuclear Information System (INIS)

    Townley, C.H.A.; Acker, D.; Laue, H.

    1990-01-01

    A thermal hydraulics evaluation of the European Fast Reactor (EFR) design followed by structural analysis is presented in this article to assess the structural integrity research programme to date. Improved design methods are being achieved as a result of the structural integrity programme for the EFR. Excellent collaboration between the nationally based research organizations and the design and construction companies has been important in achieving these improvements. (UK)

  8. Food Allergies

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Food Allergies KidsHealth / For Kids / Food Allergies What's in this ... milk eggs soy wheat What Is a Food Allergy? Food allergies happen when the immune system makes ...

  9. Food Allergy

    Science.gov (United States)

    ... Facebook and Twitter . Play our Food Allergy Bubble Game with Mr. Nose-it-All. Test your knowledge ... oral allergy syndrome? » Video: What is a red meat allergy? » Vitamin D and Food Allergy » When Should ...

  10. Milk Allergy

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Milk Allergy KidsHealth / For Teens / Milk Allergy What's in this ... to find out. What Happens With a Milk Allergy? Food allergies involve the body's immune system, which ...

  11. The growth of European fusion research

    International Nuclear Information System (INIS)

    Palumbo, D.

    1988-01-01

    The Euratom initial research programme with fusion as a modest element was constituted in 1958. Progress in fusion research mainly in the USA, USSR and UK was reported at the Geneva Conference held in September 1958. A network of national laboratories cooperating in fusion research was constituted under Association Contracts rather than founding a single Euratom laboratory. Emergence of the Tokamak became evident in 1968, and in 1969 a team from Culham travelled to Moscow to measure the electron plasma temperature and confirmed the previous Russian results. Collaboration between Culham and the European Fusion programme developed before the entrance of the UK into the European Community. The JET design team began its work in 1973. The site selected was at Culham and construction of JET commenced in 1978. Subsequent international discussions including the USA and USSR resulted in detailed design studies for a large device known as the INTOR Tokamak which will probably lead to further international cooperation. (U.K.)

  12. Fusion research in the European Community

    International Nuclear Information System (INIS)

    Wolf, G.H.

    1988-01-01

    Centering around the European joint project Joint European Torus (JET), in the framework of which hot fusion plasmas are already brought close to thermonuclear ignition, the individual research centres in Europe have taken over different special tasks. In Germany research concentrates above all on the development of super-conductive magnets, the stage of plasma-physical fundamentals or the investigation of the interaction between the plasma boundary layer and the material of the vessel wall. On this basis the development stage following JET, the Next European Torus (NET), is planned, with its main aim being the production and maintenance of a thermonuclear burning plasma, i.e. a plasma which maintains its active state from the gain of energy of its own fusion reactions. In the framework of a contractually agreed cooperation between the European Community, Japan, the USSR and the USA, the establishment of an international study group (with seat in Garching) was decided upon, which is to develop the concept of an 'International Thermonuclear Experimental Reactor (ITER)' jointly supported by these countries. The results of the studies presented show that the differences in the design data of ITER and NET are negligible. (orig./DG) [de

  13. Allergy testing - skin

    Science.gov (United States)

    Patch tests - allergy; Scratch tests - allergy; Skin tests - allergy; RAST test; Allergic rhinitis - allergy testing; Asthma - allergy testing; Eczema - allergy testing; Hayfever - allergy testing; Dermatitis - allergy testing; Allergy testing; ...

  14. Eye Allergies

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Eye Allergies Sections What Are Eye Allergies? Eye Allergy Symptoms ... allergy diagnosis Eye allergy treatment What Are Eye Allergies? Leer en Español: ¿Qué son las alergias de ...

  15. Patch test results with fragrance markers of the baseline series - analysis of the European Surveillance System on Contact Allergies (ESSCA) network 2009-2012.

    Science.gov (United States)

    Frosch, Peter J; Duus Johansen, Jeanne; Schuttelaar, Marie-Louise A; Silvestre, Juan F; Sánchez-Pérez, Javier; Weisshaar, Elke; Uter, Wolfgang

    2015-09-01

    Contact allergy to fragrances is common, and impairs quality of life, particularly in young women. To provide current results on the prevalences of sensitization to fragrance allergens used as markers in the baseline series of most European countries. Data of patients consecutively patch tested between 2009 and 2012 in 12 European countries with fragrance allergens contained in the baseline series were collected by the European Surveillance System on Contact Allergies network and descriptively analysed. Four departments used the TRUE Test(®) system. The 'basic markers' were tested on 51 477 [fragrance mix II (FM II)] to 57 123 [Myroxylon pereirae, balsam of Peru] patients, and yielded positive reactions as follows: fragrance mix I 6.9%, Myroxylon pereirae 5.4%, FM II 3.8%, colophonium 2.6%, and hydroxyisohexyl 3-cyclohexene carboxaldehyde 1.7%, with some regional differences. Prevalences with TRUE Test(®) allergens were lower. Additional fragrances were tested on 3643 (trimethylbenzenepropanol) to 14 071 (oil of turpentine) patients, and yielded between 2.6% (Cananga odorata) and 0.7% (trimethylbenzenepropanol) positive reactions. Contact allergy to fragrances is common throughout Europe, with regional variation probably being explained by patch test technique, and differences in exposure and referral patterns. The current basic markers of fragrance sensitivity in the baseline series should be supplemented with additional fragrance allergens. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. ENSAR, a Nuclear Science Project for European Research Area

    NARCIS (Netherlands)

    Turzó, Ketel; Lewitowicz, Marek; Harakeh, Muhsin N.

    2015-01-01

    During the period from September 2010 to December 2014, the European project European Nuclear Science and Applications Research (ENSAR) coordinated research activities of the Nuclear Physics community performing research in three major subfields: Nuclear Structure, Nuclear Astrophysics, and Nuclear

  17. European Research on THz Vacuum Amplifiers

    DEFF Research Database (Denmark)

    Brunetti, F.; Cojocarua, C.-S.; de Rossi, A.

    2010-01-01

    The OPTHER (OPtically Driven TeraHertz AmplifiERs) project represents a considerable advancement in the field of high frequency amplification. The design and realization of a THz amplifier within this project is a consolidation of efforts at the international level from the main players...... of the European research, academy and industry in vacuum electronics. This paper describes the status of the project and progress towards the THz amplifier realization....

  18. The 10th anniversary of the Junior Members and Affiliates of the European Academy of Allergy and Clinical Immunology.

    Science.gov (United States)

    Skevaki, Chrysanthi L; Maggina, Paraskevi; Santos, Alexandra F; Rodrigues-Alves, Rodrigo; Antolin-Amerigo, Dario; Borrego, Luis Miguel; Bretschneider, Isabell; Butiene, Indre; Couto, Mariana; Fassio, Filippo; Gardner, James; Xatzipsalti, Maria; Hovhannisyan, Lilit; Hox, Valerie; Makrinioti, Heidi; O Neil, Serena E; Pala, Gianni; Rudenko, Michael; Santucci, Annalisa; Seys, Sven; Sokolowska, Milena; Whitaker, Paul; Heffler, Enrico

    2011-12-01

    This year is the 10th anniversary of the European Academy of Allergy and Clinical Immunology (EAACI) Junior Members and Affiliates (JMAs). The aim of this review is to highlight the work and activities of EAACI JMAs. To this end, we have summarized all the initiatives taken by JMAs during the last 10 yr. EAACI JMAs are currently a group of over 2380 clinicians and scientists under the age of 35 yr, who support the continuous education of the Academy's younger members. For the past decade, JMAs enjoy a steadily increasing number of benefits such as free online access to the Academy's journals, the possibility to apply for Fellowships and the Mentorship Program, travel grants to attend scientific meetings, and many more. In addition, JMAs have been involved in task forces, cooperation schemes with other scientific bodies, organization of JMA focused sessions during EAACI meetings, and participation in the activities of EAACI communication platforms. EAACI JMA activities represent an ideal example of recruiting, training, and educating young scientists in order for them to thrive as future experts in their field. This model may serve as a prototype for other scientific communities, several of which have already adapted similar policies. © 2011 John Wiley & Sons A/S.

  19. Inside CERN European Organization for Nuclear Research

    CERN Document Server

    Pol, Andri; Heuer, Rolf

    2013-01-01

    For most people locations that hold a particular importance for the development of our society and for the advancement of science and technology remain hidden from view. CERN, the European Organization for Nuclear Research, is best known for its giant particle accelerator. Here researchers take part in a diverse array of fundamental physical research, in the pursuit of knowledge that will perhaps one dayrevolutionize our understanding of the universe and life on our planet. The Swiss photographer Andri Pol mixed with this multicultural community of researchers and followed their work over an extended period of time. In doing so he created a unique portrait of this fascinating “underworld.” The cutting-edge research is given a human face and the pictures allow us to perceive how in this world of the tiniest particles the biggest connections are searched for. With an essay by Peter Stamm.

  20. European Association of Echocardiography: Research Grant Programme.

    Science.gov (United States)

    Gargani, Luna; Muraru, Denisa; Badano, Luigi P; Lancellotti, Patrizio; Sicari, Rosa

    2012-01-01

    The European Society of Cardiology (ESC) offers a variety of grants/fellowships to help young professionals in the field of cardiological training or research activities throughout Europe. The number of grants has significantly increased in recent years with contributions from the Associations, Working Groups and Councils of the ESC. The European Association of Echocardiography (EAE) is a registered branch of the ESC and actively takes part in this initiative. One of the aims of EAE is to promote excellence in research in cardiovascular ultrasound and other imaging modalities in Europe. Therefore, since 2008, the EAE offers a Research Grant Programme to help young doctors to obtain research experience in a high standard academic centre (or similar institution oriented to clinical or pre-clinical research) in an ESC member country other than their own. This programme can be considered as a valorization of the geographical mobility as well as cultural exchanges and professional practice in the field of cardiovascular imaging. The programme has been very successful so far, therefore in 2012 the EAE has increased its offer to two grants of 25,000 euros per annum each.

  1. The EuroPrevall birth cohort study on food allergy: baseline characteristics of 12,000 newborns and their families from nine European countries.

    Science.gov (United States)

    McBride, D; Keil, T; Grabenhenrich, L; Dubakiene, R; Drasutiene, G; Fiocchi, A; Dahdah, L; Sprikkelman, A B; Schoemaker, A A; Roberts, G; Grimshaw, K; Kowalski, M L; Stanczyk-Przyluska, A; Sigurdardottir, S; Clausen, M; Papadopoulos, N G; Mitsias, D; Rosenfeld, L; Reche, M; Pascual, C; Reich, A; Hourihane, J; Wahn, U; Mills, E N C; Mackie, A; Beyer, K

    2012-05-01

    It is unclear why some children develop food allergy. The EuroPrevall birth cohort was established to examine regional differences in the prevalence and risk factors of food allergy in European children using gold-standard diagnostic criteria. The aim of this report was to describe pre-, post-natal and environmental characteristics among the participating countries. In nine countries across four major European climatic regions, mothers and their newborns were enrolled from October 2005 through February 2010. Using standardized questionnaires, we assessed allergic diseases and self-reported food hypersensitivity of parents and siblings, nutrition during pregnancy, nutritional supplements, medications, mode of delivery, socio-demographic data and home environmental exposures. A total of 12,049 babies and their families were recruited. Self-reported adverse reactions to food ever were considerably more common in mothers from Germany (30%), Iceland, United Kingdom, and the Netherlands (all 20-22%) compared with those from Italy (11%), Lithuania, Greece, Poland, and Spain (all 5-8%). Prevalence estimates of parental asthma, allergic rhinitis and eczema were highest in north-west (Iceland, UK), followed by west (Germany, the Netherlands), south (Greece, Italy, Spain) and lowest in central and east Europe (Poland, Lithuania). Over 17% of Spanish and Greek children were exposed to tobacco smoke in utero compared with only 8-11% in other countries. Caesarean section rate was highest in Greece (44%) and lowest in Spain (<3%). We found country-specific differences in antibiotic use, pet ownership, type of flooring and baby's mattress. In the EuroPrevall birth cohort study, the largest study using gold-standard diagnostic criteria for food allergy in children worldwide, we found considerable country-specific baseline differences regarding a wide range of factors that are hypothesized to play a role in the development of food allergy including allergic family history

  2. European Science Research Organisations forge closer ties

    CERN Multimedia

    2001-01-01

    Effective collaboration has always been one of the foundations of CERN's success. An essential ingredient for collaboration is communication and a new body EIROFORUM has just held its first meeting in Brussels with the aim of developing greater cross fertilization of ideas and projects. Seven organisations, CERN, EMBL (molecular biology), ESA (space activities), ESO (astronomy and astrophysics), ESRF (synchrotron radiation), ILL (neutron source) and EFDA (fusion) are currently members of EIROFORUM. Common interest between the organisations in computational grid development, materials science, instrumentation, public outreach and technology transfer has made EIROFRUM an essential group for maximising these European research organisations' resources. Increasing involvement in the Sixth Framework Programme, Europe's research guidelines for the next four years, is also one of the goals of the group. CERN takes over the chair of EIROFORUM in July 2001 and the next meeting will be held on site on 24 October .

  3. Facts and Statistics about Food Allergies

    Science.gov (United States)

    ... and Statistics with References What Is a Food Allergy? A food allergy is a medical condition in ... an emerging concern. How Many People Have Food Allergies? Researchers estimate that up to 15 million Americans ...

  4. Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy ageing) and the Global Alliance against Chronic Respiratory Diseases (GARD), a World Health Organization GARD research demonstration project.

    Science.gov (United States)

    Calderon, M A; Demoly, P; Casale, T; Akdis, C A; Bachert, C; Bewick, M; Bilò, B M; Bohle, B; Bonini, S; Bush, A; Caimmi, D P; Canonica, G W; Cardona, V; Chiriac, A M; Cox, L; Custovic, A; De Blay, F; Devillier, P; Didier, A; Di Lorenzo, G; Du Toit, G; Durham, S R; Eng, P; Fiocchi, A; Fox, A T; van Wijk, R Gerth; Gomez, R M; Haathela, T; Halken, S; Hellings, P W; Jacobsen, L; Just, J; Tanno, L K; Kleine-Tebbe, J; Klimek, L; Knol, E F; Kuna, P; Larenas-Linnemann, D E; Linneberg, A; Matricardi, M; Malling, H J; Moesges, R; Mullol, J; Muraro, A; Papadopoulos, N; Passalacqua, G; Pastorello, E; Pfaar, O; Price, D; Del Rio, P Rodriguez; Ruëff, R; Samolinski, B; Scadding, G K; Senti, G; Shamji, M H; Sheikh, A; Sisul, J C; Sole, D; Sturm, G J; Tabar, A; Van Ree, R; Ventura, M T; Vidal, C; Varga, E M; Worm, M; Zuberbier, T; Bousquet, J

    2016-01-01

    Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing.

  5. Egg Allergy

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Egg Allergy KidsHealth / For Teens / Egg Allergy What's in ... but it's worth it. What Happens With an Egg Allergy? Eggs aren't bad. But when you' ...

  6. Fish Allergy

    Science.gov (United States)

    ... Cause Blog Vision Awards Common Allergens Fish Allergy Fish Allergy Learn about fish allergy, how to read ... that you must avoid both. Allergic Reactions to Fish Finned fish can cause severe and potentially life- ...

  7. Sun Allergy

    Science.gov (United States)

    Sun allergy Overview Sun allergy is a term often used to describe a number of conditions in which an itchy red rash occurs on skin that has been exposed to sunlight. The most common form of sun allergy is ...

  8. Drug Allergy

    Science.gov (United States)

    ... Loss of consciousness Other conditions resulting from drug allergy Less common drug allergy reactions occur days or ... you take the drug. Drugs commonly linked to allergies Although any drug can cause an allergic reaction, ...

  9. Cockroach Allergy

    Science.gov (United States)

    ... the Allergist Search Health Professionals Partners Media Donate Allergies Cockroach Allergy Cockroaches are insects that live in many locations ... other children with asthma. What Is a Cockroach Allergy? Cockroaches contain a protein that is an allergen ...

  10. Latex Allergy

    Science.gov (United States)

    American Academy of Allergy Asthma & Immunology Menu Search Main navigation Skip to content Conditions & Treatments Allergies Asthma Primary Immunodeficiency Disease Related Conditions Drug Guide Conditions Dictionary Just ...

  11. The development of the MeDALL Core Questionnaires for a harmonized follow-up assessment of eleven European birth cohorts on asthma and allergies

    DEFF Research Database (Denmark)

    Hohmann, Cynthia; Pinart, Mariona; Tischer, Christina

    2014-01-01

    BACKGROUND: Numerous birth cohorts have been initiated in the world over the past 30 years using heterogeneous methods to assess the incidence, course and risk factors of asthma and allergies. The aim of the present work is to provide the stepwise proceedings of the development and current version...... of the harmonized MeDALL-Core Questionnaire (MeDALL-CQ) used prospectively in 11 European birth cohorts. METHODS: The harmonization of questions was accomplished in 4 steps: (i) collection of variables from 14 birth cohorts, (ii) consensus on questionnaire items, (iii) translation and back...

  12. Development of the Chicago Food Allergy Research Surveys: assessing knowledge, attitudes, and beliefs of parents, physicians, and the general public

    Directory of Open Access Journals (Sweden)

    Pongracic Jacqueline A

    2009-08-01

    Full Text Available Abstract Background Parents of children with food allergy, primary care physicians, and members of the general public play a critical role in the health and well-being of food-allergic children, though little is known about their knowledge and perceptions of food allergy. The purpose of this paper is to detail the development of the Chicago Food Allergy Research Surveys to assess food allergy knowledge, attitudes, and beliefs among these three populations. Methods From 2006–2008, parents of food-allergic children, pediatricians, family physicians, and adult members of the general public were recruited to assist in survey development. Preliminary analysis included literature review, creation of initial content domains, expert panel review, and focus groups. Survey validation included creation of initial survey items, expert panel ratings, cognitive interviews, reliability testing, item reduction, and final validation. National administration of the surveys is ongoing. Results Nine experts were assembled to oversee survey development. Six focus groups were held: 2/survey population, 4–9 participants/group; transcripts were reviewed via constant comparative methods to identify emerging themes and inform item creation. At least 220 participants per population were recruited to assess the relevance, reliability, and utility of each survey item as follows: cognitive interviews, 10 participants; reliability testing ≥ 10; item reduction ≥ 50; and final validation, 150 respondents. Conclusion The Chicago Food Allergy Research surveys offer validated tools to assess food allergy knowledge and perceptions among three distinct populations: a 42 item parent tool, a 50 item physician tool, and a 35 item general public tool. No such tools were previously available.

  13. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology.

    Science.gov (United States)

    Hellings, P W; Klimek, L; Cingi, C; Agache, I; Akdis, C; Bachert, C; Bousquet, J; Demoly, P; Gevaert, P; Hox, V; Hupin, C; Kalogjera, L; Manole, F; Mösges, R; Mullol, J; Muluk, N B; Muraro, A; Papadopoulos, N; Pawankar, R; Rondon, C; Rundenko, M; Seys, S F; Toskala, E; Van Gerven, L; Zhang, L; Zhang, N; Fokkens, W J

    2017-11-01

    This EAACI position paper aims at providing a state-of-the-art overview on nonallergic rhinitis (NAR). A significant number of patients suffering from persistent rhinitis are defined as nonallergic noninfectious rhinitis (NANIR) patients, often denominated in short as having NAR. NAR is defined as a symptomatic inflammation of the nasal mucosa with the presence of a minimum of two nasal symptoms such as nasal obstruction, rhinorrhea, sneezing, and/or itchy nose, without clinical evidence of endonasal infection and without systemic signs of sensitization to inhalant allergens. Symptoms of NAR may have a wide range of severity and be either continuously present and/or induced by exposure to unspecific triggers, also called nasal hyperresponsiveness (NHR). NHR represents a clinical feature of both AR and NAR patients. NAR involves different subgroups: drug-induced rhinitis, (nonallergic) occupational rhinitis, hormonal rhinitis (including pregnancy rhinitis), gustatory rhinitis, senile rhinitis, and idiopathic rhinitis (IR). NAR should be distinguished from those rhinitis patients with an allergic reaction confined to the nasal mucosa, also called "entopy" or local allergic rhinitis (LAR). We here provide an overview of the current consensus on phenotypes of NAR, recommendations for diagnosis, a treatment algorithm, and defining the unmet needs in this neglected area of research. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  14. The european hematology association roadmap for european hematology research : A consensus document

    NARCIS (Netherlands)

    A. Engert (Andreas); C.L. Balduini (Carlo); A. Brand (Anneke); B. Coiffier (Bertrand); C. Cordonnier (Charlotte); H. Döhner (Hartmut); De Wit, T.D. (Thom Duyvené); Eichinger, S. (Sabine); W.E. Fibbe (Willem); Green, T. (Tony); De Haas, F. (Fleur); A. Iolascon (Achille); T. Jaffredo (Thierry); F. Rodeghiero (Francesco); G. Salles (Gilles); J.J. Schuringa (Jan Jacob)

    2016-01-01

    textabstractThe European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European

  15. Patch test results of the European baseline series among patients with occupational contact dermatitis across Europe - analyses of the European Surveillance System on Contact Allergy network, 2002-2010.

    Science.gov (United States)

    Pesonen, Maria; Jolanki, Riitta; Larese Filon, Francesca; Wilkinson, Mark; Kręcisz, Beata; Kieć-Świerczyńska, Marta; Bauer, Andrea; Mahler, Vera; John, Swen M; Schnuch, Axel; Uter, Wolfgang

    2015-03-01

    Occupational contact dermatitis is one of the most common occupational diseases in Europe. In order to develop effective preventive measures, detailed and up-to-date data on the incidence, main causes and professions at risk of occupational contact dermatitis are needed. To describe the pattern of patch test reactivity to allergens in the European baseline series of patients with occupational contact dermatitis in different occupations. We analysed data collected by the European Surveillance System on Contact Allergy (ESSCA) network from 2002 to 2010, from 11 European countries. Allergens in the European baseline series associated with an at least doubled risk of occupational contact dermatitis include: thiuram rubber chemical accelerators, epoxy resin, and the antimicrobials methylchloroisothiazolinone/methylisothiazolinone, methyldibromo glutaronitrile, and formaldehyde. The highest risk of occupational contact dermatitis was found in occupations classified as 'other personal services workers', which includes hairdressers, nursing and other healthcare professionals, precision workers in metal and related materials, and blacksmiths, tool-makers and related trades workers. In the planning and implementation of measures aimed at preventing occupational contact dermatitis, the focus should be on the identified high-risk occupational groups and the most common occupational allergies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. All about Allergies (For Parents)

    Science.gov (United States)

    ... Allergies Egg Allergy Do Allergies Cause Asthma? Allergies Food Allergies and Travel 5 Ways to Be Prepared for an Allergy Emergency Serious Allergic Reactions (Anaphylaxis) Allergy Testing Food Allergies Food Allergies: How to Cope Egg Allergy ...

  17. Mold Allergy

    Science.gov (United States)

    ... asthma and allergies. Find certified asthma & allergy friendly® products on our certification program website or download our app on the App Store or Google Play . Medical Review October 2015. Types of Allergies Drug ... Allergy Certified Products Look for this mark to find products proven ...

  18. Fish Allergy

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Fish Allergy KidsHealth / For Parents / Fish Allergy What's in this ... Print en español Alergia al pescado About Fish Allergy A fish allergy is not exactly the same ...

  19. Shellfish Allergy

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Shellfish Allergy KidsHealth / For Parents / Shellfish Allergy What's in this ... Print en español Alergia al marisco About Shellfish Allergy A shellfish allergy is not exactly the same ...

  20. Pathogenomics: an updated European Research Agenda.

    Science.gov (United States)

    Demuth, Andreas; Aharonowitz, Yair; Bachmann, Till T; Blum-Oehler, Gabriele; Buchrieser, Carmen; Covacci, Antonello; Dobrindt, Ulrich; Emödy, Levente; van der Ende, Arie; Ewbank, Jonathan; Fernández, Luis Angel; Frosch, Matthias; García-Del Portillo, Francisco; Gilmore, Michael S; Glaser, Philippe; Goebel, Werner; Hasnain, Seyed E; Heesemann, Jürgen; Islam, Khalid; Korhonen, Timo; Maiden, Martin; Meyer, Thomas F; Montecucco, Cesare; Oswald, Eric; Parkhill, Julian; Pucciarelli, M Graciela; Ron, Eliora; Svanborg, Catharina; Uhlin, Bernt Eric; Wai, Sun Nyunt; Wehland, Jürgen; Hacker, Jörg

    2008-05-01

    The emerging genomic technologies and bioinformatics provide novel opportunities for studying life-threatening human pathogens and to develop new applications for the improvement of human and animal health and the prevention, treatment, and diagnosis of infections. Based on the ecology and population biology of pathogens and related organisms and their connection to epidemiology, more accurate typing technologies and approaches will lead to better means of disease control. The analysis of the genome plasticity and gene pools of pathogenic bacteria including antigenic diversity and antigenic variation results in more effective vaccines and vaccine implementation programs. The study of newly identified and uncultivated microorganisms enables the identification of new threats. The scrutiny of the metabolism of the pathogen in the host allows the identification of new targets for anti-infectives and therapeutic approaches. The development of modulators of host responses and mediators of host damage will be facilitated by the research on interactions of microbes and hosts, including mechanisms of host damage, acute and chronic relationships as well as commensalisms. The study of multiple pathogenic and non-pathogenic microbes interacting in the host will improve the management of multiple infections and will allow probiotic and prebiotic interventions. Needless to iterate, the application of the results of improved prevention and treatment of infections into clinical tests will have a positive impact on the management of human and animal disease. The Pathogenomics Research Agenda draws on discussions with experts of the Network of Excellence "EuroPathoGenomics" at the management board meeting of the project held during 18-21 April 2007, in the Villa Vigoni, Menaggio, Italy. Based on a proposed European Research Agenda in the field of pathogenomics by the ERA-NET PathoGenoMics the meeting's participants updated the established list of topics as the research agenda for

  1. Nasal allergies hayfever among young adults in Melbourne, Australia

    Directory of Open Access Journals (Sweden)

    Michael Abramson

    1997-01-01

    Full Text Available Although there is wide variation in the prevalence of nasal allergies internationally, the extent to which this is due to variation in etiological factors is not known. The purpose of the present study was to define the relative importance of atopy and other risk factors for nasal allergies, including hayfever, among young adults in Melbourne. The subjects were participants in the second phase of the European Community Respiratory Health Survey; 876 adults between 20 and 45 years of age completed a detailed respiratory questionnaire, 745 had skin prick testing with common aeroallergens and 675 underwent methacholine challenge. Total and allergen-specific IgE levels were measured in 701 and 693 subjects by radioimmunoassay and RAST, respectively. Nasal allergies, including hayfever, were reported by 47.5% of randomly selected participants. Females, non- smokers, subjects with a family history of allergies, those with current asthma, a history of eczema and nasal symptoms induced by dust, pollen or food were significantly more likely to have nasal allergies. Oral antihistamines had been used by 45.7% of those reporting nasal allergies and 12.4% had received allergen immunotherapy. The risk of nasal allergies, including hayfever, was increased 6.1-fold by atopy, particularly by positive skin tests to outdoor allergens such as Birch, Timothy grass, plantain, olive, Cladosporium and Rye grass pollen. Total serum IgE was significantly higher in subjects reporting nasal allergies than in those who did not report such allergies. There were significant trends in the prevalence of nasal allergies with increasing titers of specific IgE directed against all allergens tested. In conclusion, the significant independent risk factors for nasal allergies, including hayfever, in young adults were atopy, particularly sensitization to Timothy grass, house dust mites and plantain, current asthma, not smoking, a history of eczema and female gender. Future research

  2. Clinical update on contact allergy

    DEFF Research Database (Denmark)

    Uter, Wolfgang; Johansen, Jeanne Duus; Orton, David I

    2005-01-01

    PURPOSE OF REVIEW: The aim of this article is to review recent findings in contact allergy, regarding clinical research. RECENT FINDINGS: The biocide methyldibromo glutaronitrile was identified to be an important sensitizer. Subsequently, it was banned from leave-on cosmetics in the European Union....... Another group of important allergens that have been studied extensively included the fragrances oak moss absolute, isoeugenol, hydroxyisohexyl 3-cyclohexene carboxaldehyde and farnesol. A new fragrance mix II has been developed for standard testing, which includes the two latter compounds. Dose response...... a classification of newly introduced chemicals; increasingly, the local lymph node assay is supplementing and potentially replacing the guinea pig maximization test. Recent advances in occupational contact allergy include, for example, some attempts to improve diagnostics for epoxy resin and other plastic, glue...

  3. A European Perspective on Security Research

    Science.gov (United States)

    Liem, Khoen; Hiller, Daniel; Castex, Christoph

    Tackling the complexity and interdependence of today's security environment in the globalized world of the 21st century is an everlasting challenge. Whereas the end of the Cold War presented a caesura of global dimension for the political and economic architecture and a realignment of power distribution and international relations between former adversaries, September 11th of 2001 may be seen as another caesura. Since then, specifically among countries of the Western hemisphere, traditional security paradigms and theories have been critically questioned and the different security cultures and perceptions have resulted in diverse security and defence policies as well as in security research efforts of individual countries. Consensus, it seems, exists on the question of what the threats are that our modern interconnected societies are facing. Whether looking at international terrorism, organized crime, climate change, the illegal trafficking of goods and people or naturally caused catastrophes, these phenomena all have in common that they are in most cases of transnational nature. Formerly existing dividing lines between internal and external security continue to fade, presenting an enormous challenge for those in charge of designing security policy and even more so for the various institutions safeguarding European security. That is why dissent often revolves around the question on how to get hold of these complex problems. Geographic location, cultural background, ethical make-up of society as well as relations with neighbouring countries are all important aspects to be considered when assessing the security culture and policy of individual countries.

  4. European Academy of Allergy and Clinical Immunology task force report on 'dose-response relationship in allergen-specific immunotherapy'

    DEFF Research Database (Denmark)

    Calderón, M A; Larenas, D; Kleine-Tebbe, J

    2011-01-01

    For a century, allergen-specific immunotherapy (SIT) has proven to be an effective treatment for allergic rhinitis, asthma, and insect sting allergy. However, as allergen doses are frequently adapted to the individual patient, there are few data on dose-response relationship in SIT. Allergen prod...

  5. [Food allergy in adulthood].

    Science.gov (United States)

    Werfel, Thomas

    2016-06-01

    Food allergies can newly arise in adulthood or persist following a food allergy occurring in childhood. The prevalence of primary food allergy is basically higher in children than in adults; however, in the routine practice food allergies in adulthood appear to be increasing and after all a prevalence in Germany of 3.7 % has been published. The clinical spectrum of manifestations of food allergies in adulthood is broad. Allergy symptoms of the immediate type can be observed as well as symptoms occurring after a delay, such as indigestion, triggering of hematogenous contact eczema or flares of atopic dermatitis. The same principles for diagnostics apply in this group as in childhood. In addition to the anamnesis, skin tests and in vitro tests, as a rule elimination diets and in particular provocation tests are employed. Molecular allergy diagnostics represent a major step forward, which allow a better assessment of the risk of systemic reactions to certain foodstuffs (e.g. peanuts) and detection of cross-reactions in cases of apparently multiple sensitivities. Current German and European guidelines from 2015 are available for the practical approach to clarification of food allergies. The most frequent food allergies in adults are nuts, fruit and vegetables, which can cross-react with pollen as well as wheat, shellfish and crustaceans. The therapy of allergies involves a consistent avoidance of the allogen. Detailed dietary plans are available with avoidance strategies and instructions for suitable food substitutes. A detailed counseling of affected patients by specially trained personnel is necessary especially in order to avoid nutritional deficiencies and to enable patients to enjoy a good quality of life.

  6. Peanut allergy.

    LENUS (Irish Health Repository)

    Hourihane, Jonathan O'B

    2011-04-01

    Peanut allergy may affect up to 2% of children in some countries, making it one of the most common conditions of childhood. Peanut allergy is a marker of a broad and possibly severe atopic phenotype. Nearly all children with peanut allergy have other allergic conditions. Peanut accounts for a disproportionate number of fatal and near fatal food-related allergies. Families with a child or children with peanut allergy can struggle to adapt to the stringent avoidance measures required. Although oral induction of tolerance represents the cutting edge of peanut allergy management, it is not yet ready for routine practice.

  7. Flood Risk Research and Warning Tools at the European Scale

    NARCIS (Netherlands)

    Roo, A.P.J. de; Thielen, J.; Feyen, L.; Burek, P.; Salamon, P.

    2012-01-01

    The floods in the rivers Meuse and Rhine in 1993 and 1995 made the European Commission realize that also at Commission level further research on floods – especially in transboundary river catchments - was necessary. This led to the start of a dedicated research project on floods at the European

  8. Nuclear research and development in the European community

    International Nuclear Information System (INIS)

    1979-01-01

    Research programmes undertaken by the European Atomic Energy Community and the European Economic Community are discussed. These programmes are carried out both at the Communities own Joint Research Centres (at Ispra, Karlsruhe, Geel and Petten) and also, although centrally managed by the Commission, at research organizations in the Member States. Such research projects include radioactive waste management and storage, decommissioning of nuclear power stations and nuclear fusion. Culham Laboratory is not only the centre for the UKAEA's research into controlled thermonuclear fusion but is also host to the Joint European Torus Joint Undertaking. (U.K.)

  9. Drug Allergy

    African Journals Online (AJOL)

    EL-HAKIM

    Immunology Unit, Department of Pediatrics, Ain Shams University, Cairo ... the case with food allergies).7,8 The parentral route ..... molecular-weight agents. ... and lack positive controls. ..... Immunology; Joint Council of Allergy, Asthma and.

  10. Food Allergy

    Science.gov (United States)

    ... 1,3-galactose, a carbohydrate found on mammalian meat, and is associated with being bitten by the ... home. Treating Food Allergies There is currently no cure for food allergy, but there are many promising ...

  11. Allergies - overview

    Science.gov (United States)

    ... used to treat food allergies because of the danger of a severe reaction. Allergy shots may need ... allergic or immunologic disease. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine . 25th ed. Philadelphia, PA: ...

  12. Penicillin Allergy

    Science.gov (United States)

    ... Seizures Loss of consciousness Other conditions resulting from penicillin allergy Less-common penicillin allergy reactions occur days ... immune system to create an antibody to it. Penicillins and related drugs Penicillins belong to a class ...

  13. Food allergy

    Science.gov (United States)

    ... questions about the food you are served. When buying food, read package ingredients carefully. ... allergies in breastfed or other children to prevent future food allergies. Always discuss this with your child's ...

  14. Soy Allergy

    Science.gov (United States)

    ... Many foods, such as meat products, bakery goods, chocolate and breakfast cereals, may contain soy. Symptoms For ... greater risk of developing a soy allergy: Family history. You're at increased risk of allergy to ...

  15. Food Allergy

    Science.gov (United States)

    Food allergy is an abnormal response to a food triggered by your body's immune system. In adults, the foods ... a severe reaction called anaphylaxis. Symptoms of food allergy include Itching or swelling in your mouth Vomiting, ...

  16. Allergy Capitals

    Science.gov (United States)

    ... to face one of the season’s biggest problems: tree pollen . Common symptoms of springtime allergies include: Runny nose Itchy eyes Sneezing Congestion “Our Spring Allergy Capitals report is a valuable tool to help identify cities where seasonal allergy symptoms can create challenges,” ...

  17. Strategies for public health research in European Union countries.

    Science.gov (United States)

    Grimaud, Olivier; McCarthy, Mark; Conceição, Claudia

    2013-11-01

    'Health' is an identifiable theme within the European Union multi-annual research programmes. Public Health Innovation and Research in Europe (PHIRE), led by the European Public Health Association, sought to identify public health research strategies in EU member states. Within PHIRE, national public health associations reviewed structures for health research, held stakeholder workshops and produced reports. This information, supplemented by further web searches, including using assisted translation, was analysed for national research strategies and health research strategies. All countries described general research strategies, outlining organizational and capacity objectives. Thematic fields, including health, are mentioned in some strategies. A health research strategy was identified for 15 EU countries and not for 12. Ministries of health led research strategies for nine countries. Public health research was identified in only three strategies. National research strategies did not refer to the European Union's health research programme. Public health research strategies of European countries need to be developed by ministries of health, working with the research community to achieve the European Research Area.

  18. Prevalence of contact allergy to metals in the European general population with a focus on nickel sulfate and piercings: The EDEN Fragrance Study.

    Science.gov (United States)

    Schuttelaar, Marie L A; Ofenloch, Robert F; Bruze, Magnus; Cazzaniga, Simone; Elsner, Peter; Gonçalo, Margarida; Naldi, Luigi; Svensson, Åke; Diepgen, Thomas L

    2018-04-10

    Studies on sensitization to metals in the general population are scarce. To determine the prevalence of sensitization to metals in the general population, and factors associated with nickel sensitization. In 5 European countries (The Netherlands, Germany, Italy, Portugal and Sweden), a random sample (N = 3119) from the general population (aged 18-74 years) was patch tested and interviewed by use of a questionnaire on exposure to metals, piercing, and jewellery. Overall, the age-standardized prevalences of sensitization to nickel, cobalt and chromium were, respectively, 14.5%, 2.1%, and 0.8%. The highest prevalence of nickel sensitization was seen in Portugal (18.5%) and the lowest (8.3%) in Sweden. The prevalence of cobalt sensitization varied between 3.8% (The Netherlands) and 0.9% (Italy), and the prevalence of chromium sensitization varied between 1.3% (Portugal) and 0.2% (Sweden). Significant associations were observed between nickel allergy and female sex (odds ratio [OR] 5.19; 95% confidence interval [95%CI]: 3.99-6.74), past piercing use (OR 3.86; 95%CI: 2.85-5.24), and currently having ≥3 piercings (OR 5.58; 95%CI: 4.02-7.76). The prevalence of sensitization to metals in the European general population was high, mostly because of nickel. The lowest prevalence of contact allergy to nickel and chromium observed in Sweden supports the effectiveness of long-standing regulation. © 2018 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.

  19. The JET project and the European fusion research programme

    International Nuclear Information System (INIS)

    Wuester, H.-O.

    1984-01-01

    The paper concerns the Joint European Torus (JET) project and the European Fusion Research Programme. Fusion as an energy source and commercial fusion power are briefly discussed. The main features of the JET apparatus and the tokamak magnetic field configuration are given. Also described are the specific aims of JET, and the proposed future fusion reactor programme. (U.K.)

  20. Contact allergy to spices

    NARCIS (Netherlands)

    W. Van den Akker Th. (W.); I.D. Roesyanto-Mahadi (I.); A.W. van Toorenenbergen (Albert); Th. van Joost (Theo)

    1990-01-01

    textabstractA group of 103 patients suspected of contact allergy was tested with the European standard series, wood tars and spices; paprika, cinnamon, laurel, celery seed, nutmeg, curry, black pepper, cloves, while pepper, coriander, cacao and garlic. 32 patients (Group I) were selected on the

  1. Food allergy

    Directory of Open Access Journals (Sweden)

    Youngshin Han

    2012-05-01

    Full Text Available Food allergy is an important public health problem affecting 5% of infants and children in Korea. Food allergy is defined as an immune response triggered by food proteins. Food allergy is highly associated with atopic dermatitis and is one of the most common triggers of potentially fatal anaphylaxis in the community. Sensitization to food allergens can occur in the gastrointestinal tract (class 1 food allergy or as a consequence of cross reactivity to structurally homologous inhalant allergens (class 2 food allergy. Allergenicity of food is largely determined by structural aspects, including cross-reactivity and reduced or enhanced allergenicity with cooking that convey allergenic characteristics to food. Management of food allergy currently focuses on dietary avoidance of the offending foods, prompt recognition and treatment of allergic reactions, and nutritional support. This review includes definitions and examines the prevalence and management of food allergies and the characteristics of food allergens.

  2. Fragrance contact allergy in Iran.

    Science.gov (United States)

    Firooz, A; Nassiri-Kashani, M; Khatami, A; Gorouhi, F; Babakoohi, S; Montaser-Kouhsari, L; Davari, P; Dowlati, Y

    2010-12-01

    Fragrances are considered as one of the most common causes of allergic contact dermatitis. About 1-4% of the general population suffer from fragrance contact allergy (FCA). To determine the frequency of FCA and its clinical relevance in a sample of Iranian patients with history of contact and/or atopic dermatitis from January 2004 to December 2008. Standardized patch testing with 28-allergen screening series recommended by the German Contact Dermatitis Research Group and European Standard Series was used at six dermatological clinics in Iran. Fragrance allergens comprised of fragrance mix I (FM I), Myroxylon pereirae (MP; balsam of Peru), Lyral, turpentine and FM II. Fragrance contact allergy was detected in 7.2% of the patients. The frequency of positive reactions to FM I, MP and FM II were 3.7% (41/1105), 2.8% (32/1135) and 1.1% (3/267) respectively. 82.4% of the reactions to fragrance allergens were clinically relevant. The most common involved areas were hands (68.4%) and face (35.4%). Fragrance allergy predominantly affected women aged more than 40 years (P=0.008). Positive reaction to more than two allergens was significantly higher in FCA patients compared with other contact dermatitis patients (P<0.0001), and FM I, nickel and MP were the most frequent allergens in these patients. Despite less frequency of FCA in comparison with some European countries, its clinical relevance in Iranian patients seems to be high. It mostly affects the hands and the face predominantly in women aged more than 40 years. © 2010 The Authors. Journal compilation © 2010 European Academy of Dermatology and Venereology.

  3. Food allergy: epidemiology and natural history.

    Science.gov (United States)

    Savage, Jessica; Johns, Christina B

    2015-02-01

    The prevalence of food allergy is rising for unclear reasons, with prevalence estimates in the developed world approaching 10%. Knowledge regarding the natural course of food allergies is important because it can aid the clinician in diagnosing food allergies and in determining when to consider evaluation for food allergy resolution. Many food allergies with onset in early childhood are outgrown later in childhood, although a minority of food allergy persists into adolescence and even adulthood. More research is needed to improve food allergy diagnosis, treatment, and prevention. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. European Research Reactor Conference (RRFM) 2015: Conference Proceedings

    International Nuclear Information System (INIS)

    2015-01-01

    In 2015 the European Research Reactor Conference, RRFM, took place in Bucharest, Romania. The conference programme resolved around a series of plenary sessions dedicated to the latest global developments with regards to research reactor technology and management. Parallel sessions focused on all areas of the fuel cycle of research reactors, their utilisation, operation and management as well as new research reactor projects and Innovative methods in reactor physics and thermo-hydraulics. The European Research Reactor Conference also gave special attention to safety and security of research reactors

  5. European Research Reactor Conference (RRFM) 2016: Conference Proceedings

    International Nuclear Information System (INIS)

    2016-01-01

    The 2016 European Research Reactor Conference, RRFM, took place in Berlin, Germany. The conference programme resolved around a series of plenary sessions dedicated to the latest global developments with regards to research reactor technology and management. Parallel sessions focused on all areas of the fuel cycle of research reactors, their utilisation, operation and management as well as new research reactor projects and Innovative methods in reactor physics and thermo-hydraulics. The European Research Reactor Conference also gave special attention to safety and security of research reactors.

  6. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy

    NARCIS (Netherlands)

    Muraro, A.; Werfel, T.; Hoffmann-Sommergruber, K.; Roberts, G.; Beyer, K.; Bindslev-Jensen, C.; Cardona, V.; Dubois, A.; duToit, G.; Eigenmann, P.; Fernandez Rivas, M.; Halken, S.; Hickstein, L.; Høst, A.; Knol, E.; Lack, G.; Marchisotto, M. J.; Niggemann, B.; Nwaru, B. I.; Papadopoulos, N. G.; Poulsen, L. K.; Santos, A. F.; Skypala, I.; Schoepfer, A.; van Ree, R.; Venter, C.; Worm, M.; Vlieg-Boerstra, B.; Panesar, S.; de Silva, D.; Soares-Weiser, K.; Sheikh, A.; Ballmer-Weber, B. K.; Nilsson, C.; de Jong, N. W.; Akdis, C. A.

    2014-01-01

    Food allergy can result in considerable morbidity, impact negatively on quality of life, and prove costly in terms of medical care. These guidelines have been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group, building on

  7. EAACI Food Allergy and Anaphylaxis Guidelines: managing patients with food allergy in the community

    NARCIS (Netherlands)

    Muraro, A.; Agache, I.; Clark, A.; Sheikh, A.; Roberts, G.; Akdis, C. A.; Borrego, L. M.; Higgs, J.; Hourihane, J. O.'B.; Jorgensen, P.; Mazon, A.; Parmigiani, D.; Said, M.; Schnadt, S.; van Os-Medendorp, H.; Vlieg-Boerstra, B. J.; Wickman, M.

    2014-01-01

    The European Academy of Allergy and Clinical Immunology (EAACI) Food Allergy and Anaphylaxis Guidelines, managing patients with food allergy (FA) in the community, intend to provide guidance to reduce the risk of accidental allergic reactions to foods in the community. This document is intended to

  8. EAACI Food Allergy and Anaphylaxis Guidelines : Food allergy health-related quality of life measures

    NARCIS (Netherlands)

    Muraro, A.; Dubois, Anthony; DunnGalvin, A.; Hourihane, J. O'B.; de Jong, N. W.; Meyer, R.; Panesar, S. S.; Roberts, G.; Salvilla, S.; Sheikh, A.; Worth, A.; Flokstra-de Blok, B. M. J.

    Instruments have been developed and validated for the measurement of health-related quality of life in patients with food allergy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group. It draws on a

  9. European Researchers Night, Students on Shift at ALICE

    CERN Multimedia

    Fons Rademakers

    2010-01-01

    During European Researchers' Night, on Friday 24 September 2010, from 17:00 to 24:00, pupils from French and Swiss schools visited ALICE and took shifts in the control room, helping the ALICE physicists run the experiment.

  10. Research needs in allergy: an EAACI position paper, in collaboration with EFA

    NARCIS (Netherlands)

    Papadopoulos, Nikolaos G.; Agache, Ioana; Bavbek, Sevim; Bilo, Beatrice M.; Braido, Fulvio; Cardona, Victoria; Custovic, Adnan; Demonchy, Jan; Demoly, Pascal; Eigenmann, Philippe; Gayraud, Jacques; Grattan, Clive; Heffler, Enrico; Hellings, Peter W.; Jutel, Marek; Knol, Edward; Lötvall, Jan; Muraro, Antonella; Poulsen, Lars K.; Roberts, Graham; Schmid-Grendelmeier, Peter; Skevaki, Chrysanthi; Triggiani, Massimo; Vanree, Ronald; Werfel, Thomas; Flood, Breda; Palkonen, Susanna; Savli, Roberta; Allegri, Pia; Annesi-Maesano, Isabella; Annunziato, Francesco; Antolin-Amerigo, Dario; Apfelbacher, Christian; Blanca, Miguel; Bogacka, Ewa; Bonadonna, Patrizia; Bonini, Matteo; Boyman, Onur; Brockow, Knut; Burney, Peter; Buters, Jeroen; Butiene, Indre; Calderon, Moises; Cardell, Lars Olaf; Caubet, Jean-Christoph; Celenk, Sevcan; Cichocka-Jarosz, Ewa; Cingi, Cemal; Couto, Mariana; Dejong, Nicolette; del Giacco, Stefano; Douladiris, Nikolaos; Fassio, Filippo; Fauquert, Jean-Luc; Fernandez, Javier; Rivas, Montserrat Fernandez; Ferrer, Marta; Flohr, Carsten; Gardner, James; Genuneit, Jon; Gevaert, Philippe; Groblewska, Anna; Hamelmann, Eckard; Hoffmann, Hans Jürgen; Hoffmann-Sommergruber, Karin; Hovhannisyan, Lilit; Hox, Valérie; Jahnsen, Frode L.; Kalayci, Omer; Kalpaklioglu, Ayse Füsun; Kleine-Tebbe, Jörg; Konstantinou, George; Kurowski, Marcin; Lau, Susanne; Lauener, Roger; Lauerma, Antti; Logan, Kirsty; Magnan, Antoine; Makowska, Joanna; Makrinioti, Heidi; Mangina, Paraskevi; Manole, Felicia; Mari, Adriano; Mazon, Angel; Mills, Clare; Mingomataj, Ervinç; Niggemann, Bodo; Nilsson, Gunnar; Ollert, Markus; O'Mahony, Liam; O'Neil, Serena; Pala, Gianni; Papi, Alberto; Passalacqua, Gianni; Perkin, Michael; Pfaar, Oliver; Pitsios, Constantinos; Quirce, Santiago; Raap, Ulrike; Raulf-Heimsoth, Monika; Rhyner, Claudio; Robson-Ansley, Paula; Alves, Rodrigo Rodrigues; Roje, Zeljka; Rondon, Carmen; Rudzeviciene, Odilija; Ruëff, Franziska; Rukhadze, Maia; Rumi, Gabriele; Sackesen, Cansin; Santos, Alexandra F.; Santucci, Annalisa; Scharf, Christian; Schmidt-Weber, Carsten; Schnyder, Benno; Schwarze, Jürgen; Senna, Gianenrico; Sergejeva, Svetlana; Seys, Sven; Siracusa, Andrea; Skypala, Isabel; Sokolowska, Milena; Spertini, Francois; Spiewak, Radoslaw; Sprikkelman, Aline; Sturm, Gunter; Swoboda, Ines; Terreehorst, Ingrid; Toskala, Elina; Traidl-Hoffmann, Claudia; Venter, Carina; Vlieg-Boerstra, Berber; Whitacker, Paul; Worm, Margitta; Xepapadaki, Paraskevi; Akdis, Cezmi A.

    2012-01-01

    In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More

  11. "We have made Europe, now we have to make Europeans." Researching European Identity Among Flemish Youths

    Directory of Open Access Journals (Sweden)

    Petra Huyst

    2008-12-01

    Full Text Available After the rejection of the European Constitution in 2005, questions were raised about if and how European citizens feel connected to the European Union (EU. This article examines the image young, Flemish people have of the EU and whether they feel some sense of belonging in the EU. The research draws upon a qualitative study in which Flemish young people were asked how they felt towards the EU and how they perceived it. Using a social-constructionist perspective, the first part of the article concentrates on the concept of European identity and the theoretical divide between a civic and a cultural European political identity, as proposed by Bruter (2004. The second part of the article focuses on the results of a series of focus groups with young people (aged 17 to 19, held in spring 2007. The article argues that no strong European identity is yet present in the hearts and minds of these young people, although contexts and interactions might evoke a limited notion of European identity. This article offers an empirical account of a theoretical debate and presents a critical understanding of the dynamics at play in European identity construction.

  12. Research Strategies in European Union Studies

    DEFF Research Database (Denmark)

    Manners, Ian James; Lynggaard, Kennet; Löfgren, Karl

    2015-01-01

    The contributing chapters of this book all illustrate the richness and diversity of problem-driven research in EU studies. This concluding chapter draws together the insights of this rich diversity in order to move the study of research strategies beyond the dichotomies of the past towards a new...... agenda for research on Europe. The crisis gripping the EU in the 21st century is not just an economic crisis, it is a crisis of belief in the EU. Research on the EU is deeply implicated in this crisis, not least because of the questions it does not ask, but also because of the pereceived weakness...... of demonstrating the methods and evidence used. A new agenda for research on Europe needs to acknowledge these weaknesses of the past and move beyond dichotomies towards greater awareness and openesss of the importance of research strategies, designs and methods....

  13. The European Hematology Association Roadmap for European Hematology Research: a consensus document.

    Science.gov (United States)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    2016-02-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients. Copyright© Ferrata Storti Foundation.

  14. Feature: Controlling Seasonal Allergies | NIH Medlineplus the Magazine

    Science.gov (United States)

    ... this page please turn Javascript on. Feature: Seasonal Allergies Controlling Seasonal Allergies Past Issues / Spring 2012 Table of Contents In ... to allergens, helping to prevent allergic reactions. Seasonal Allergy Research at NIH Allergen and T-Cell Reagent ...

  15. The European Network of Coloproctology: a strategy towards the European research and healthcare system.

    Science.gov (United States)

    Rubbini, Michele

    2016-12-01

    Many documents from the International Institutions point out that Health represents an engine of economic and social development. Based on these documents and concepts, the European Parliament decided to create a system of European Reference Networks as a synthesis of clinical and research activities, particularly in the field of rare diseases. This initiative, properly implemented, could be first step towards a new European health system. This article instead, wanting to deepen this perspective, postulates that the ERNs may also be related to widespread diseases, such as those of coloproctological interest, with the aim of setting up a European Network of Coloproctology (ENCP). Here are analyzed: (a) the documents related to ERNs and others related to research and training, the characteristics of the coloproctological diseases, and proposal of the ENCP; (b) a survey that involves 14 out of 25 of the National and Regional Representative of the European Society of Coloproctology. Hundred percent of the people interviewed agree to the ENCP project. The percentage of the approved proposed fields of activity of the ENCP are: Healthcare 71%, Research 100%, Training 86%, Support to legislation 78%, Professional Mobility 64%, Patient Database 71%, and Expenditure control 64%. From the analysis of the documents and the result of the survey, ERNs are appropriate not only in relation to rare diseases but also in those fields with higher diffusion and the creation of a European Network of Coloproctology is then postulated.

  16. RRFM (European Research Reactor Conference) 2011 Transactions

    International Nuclear Information System (INIS)

    2011-01-01

    The RRFM conference is an international forum for researchers, operators and decision-makers to discuss all significant aspects of Research Reactor utilisation. In order to improve operational efficiency and fuel safety and contribute to the search for back-end solutions for spent fuel

  17. Occupational Animal Allergy.

    Science.gov (United States)

    Stave, Gregg M

    2018-02-16

    This review explores animal allergen exposure in research laboratories and other work settings, focusing on causes and prevention. (1) Consistent with the hygiene hypothesis, there is new evidence that early childhood exposure to pets produces changes in the gut microbiome that likely lead to a lower risk of allergy. (2) Anaphylaxis from laboratory animal bites occurs more frequently than suggested by prior literature. (3) Animal allergens represent an occupational hazard in a wide variety of work settings ranging from fields that work with animals to public settings like schools and public transportation where allergens are brought into or are present in the workplace. Exposure to animal allergens can result in allergy, asthma, and anaphylaxis. Animal allergy has been most studied in the research laboratory setting, where exposure reduction can prevent the development of allergy. Similar prevention approaches need to be considered for other animal work environments and in all settings where animal allergens are present.

  18. Pet Allergy Quiz

    Science.gov (United States)

    ... Treatments ▸ Allergies ▸ Pet Allergy ▸ Pet Allergy Quiz Share | Pet Allergy Quiz More than half of U.S. households ... cat family. Yet, millions of people suffer from pet allergies. Take this quiz to test your knowledge ...

  19. Food allergy

    National Research Council Canada - National Science Library

    Maleki, Soheila J; Burks, A. Wesley; Helm, Ricki M

    2006-01-01

    ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2. Exploring Current and Novel Methods for the Detection and Diagnosis of Food Allergy: the Clinical Approach * Adriano Mari and Enrico Scala...

  20. Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology.

    Science.gov (United States)

    Hartmann, Karin; Escribano, Luis; Grattan, Clive; Brockow, Knut; Carter, Melody C; Alvarez-Twose, Ivan; Matito, Almudena; Broesby-Olsen, Sigurd; Siebenhaar, Frank; Lange, Magdalena; Niedoszytko, Marek; Castells, Mariana; Oude Elberink, Joanna N G; Bonadonna, Patrizia; Zanotti, Roberta; Hornick, Jason L; Torrelo, Antonio; Grabbe, Jürgen; Rabenhorst, Anja; Nedoszytko, Boguslaw; Butterfield, Joseph H; Gotlib, Jason; Reiter, Andreas; Radia, Deepti; Hermine, Olivier; Sotlar, Karl; George, Tracy I; Kristensen, Thomas K; Kluin-Nelemans, Hanneke C; Yavuz, Selim; Hägglund, Hans; Sperr, Wolfgang R; Schwartz, Lawrence B; Triggiani, Massimo; Maurer, Marcus; Nilsson, Gunnar; Horny, Hans-Peter; Arock, Michel; Orfao, Alberto; Metcalfe, Dean D; Akin, Cem; Valent, Peter

    2016-01-01

    Cutaneous lesions in patients with mastocytosis are highly heterogeneous and encompass localized and disseminated forms. Although a classification and criteria for cutaneous mastocytosis (CM) have been proposed, there remains a need to better define subforms of cutaneous manifestations in patients with mastocytosis. To address this unmet need, an international task force involving experts from different organizations (including the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology) met several times between 2010 and 2014 to discuss the classification and criteria for diagnosis of cutaneous manifestations in patients with mastocytosis. This article provides the major outcomes of these meetings and a proposal for a revised definition and criteria. In particular, we recommend that the typical maculopapular cutaneous lesions (urticaria pigmentosa) should be subdivided into 2 variants, namely a monomorphic variant with small maculopapular lesions, which is typically seen in adult patients, and a polymorphic variant with larger lesions of variable size and shape, which is typically seen in pediatric patients. Clinical observations suggest that the monomorphic variant, if it develops in children, often persists into adulthood, whereas the polymorphic variant may resolve around puberty. This delineation might have important prognostic implications, and its implementation in diagnostic algorithms and future mastocytosis classifications is recommended. Refinements are also suggested for the diagnostic criteria of CM, removal of telangiectasia macularis eruptiva perstans from the current classification of CM, and removal of the adjunct solitary from the term solitary mastocytoma. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  1. Protecting animals and enabling research in the European Union

    DEFF Research Database (Denmark)

    Olsson, I. Anna S.; Pinto da Silva, Sandra; Townend, David

    2016-01-01

    In 1986, European Directive 86/609/EEC, regulating the use of animals in research, was one of the first examples of common legislation to set standards for animal protection across the Member States of the former European Economic Community, now the European Union, with the aim of securing a level...... objectives of the directive, particularly with a focus on securing the same high standards of animal protection across member countries. The analysis focuses on three separate issues: (1) minimum standards for laboratory animal housing and care, (2) restrictions on the use of certain animal species, and (3...

  2. AIDA – pushing the boundaries of European particle detector research

    CERN Multimedia

    Naomi Gilraen Wyles

    2011-01-01

    AIDA (Advanced European Infrastructures for Detectors at Accelerators), a new project co-funded by the European Union and worth a total of 26 million euros, will be officially launched at CERN next week. The kick-off meeting will take place on 16-18 February, during which Europe-wide detector physicists will come together to begin work on detector infrastructure developments for future particle physics experiments.   Coordinated by CERN, AIDA involves more than 80 institutes and laboratories from 23 countries as beneficiaries or associate partners (the full list can be found here). This four-year project will receive 8 million euros from the European Commission's FP7 Research Infrastructures programme. AIDA will develop facilities covering the four main goals identified by the European Strategy for Particle Physics. These are the LHC upgrade, Linear Colliders, Neutrino facilities and Super-B factories. These facilities will also be available for other researchers in the fields of nuclear and par...

  3. Pediatric allergy and immunology in Italy.

    Science.gov (United States)

    Tozzi, Alberto E; Armenio, Lucio; Bernardini, Roberto; Boner, Attilio; Calvani, Mauro; Cardinale, Fabio; Cavagni, Giovanni; Dondi, Arianna; Duse, Marzia; Fiocchi, Alessandro; Marseglia, Gian L; del Giudice, Michele Miraglia; Muraro, Antonella; Pajno, Giovanni B; Paravati, Francesco; Peroni, Diego; Tripodi, Salvatore; Ugazio, Alberto G; Indinnimeo, Luciana

    2011-05-01

    In Italy, according to the International Study on Asthma and Allergies in Childhood study, the prevalence of current asthma, allergic rhinoconjunctivitis, and atopic eczema in 2006 was 7.9%, 6.5%, and 10.1% among children aged 6-7 and 8.4%, 15.5%, and 7.75% among children aged 13-14 yr. University education in this field is provided by the Postgraduate Schools of Pediatrics and those of Allergology and Clinical Immunology, as well as several annual Master courses. The Italian Society of Pediatric Allergology and Immunology (SIAIP) was founded in 1996 and counts about 1000 members. SIAIP promotes evidence-based management of allergic children and disseminates information to patients and their families through a quite innovative website and the National Journal 'Rivista Italiana di Allergologia Pediatrica'. In the last decade, four major regional, inter-regional, and national web-based networks have been created to link pediatric allergy centers and to share their clinical protocols and epidemiologic data. In addition, National Registers of Primary Immune-deficiencies and on Pediatric HIV link all clinical excellence centers. Research projects in the field of pediatric allergy and immunology are founded by the Italian Ministry of Education, University and Research (MIUR) and by the National Research Council (CNR), but the overall investments in this research area are quite low. Only a handful Italian excellence centers participate in European Projects on Pediatric Allergy and Immunology within the 7th Framework Program. The European Academy of Allergy and Clinical Immunology currently hosts two Italians in its Executive Committee (EC) and one in the EC of the Pediatric Section; moreover, major European Academy of Allergy and Clinical Immunology meetings and courses in the area of pediatrics (e.g., PAAM, Venice, 2009) have been held in Italy in the last 3 yr. Italian hallmarks in the management of allergic diseases in childhood are a quite alive and spread interest in

  4. Advances in food allergy in 2015.

    Science.gov (United States)

    Wood, Robert A

    2016-12-01

    This review highlights research advances in food allergy that were published in the Journal in 2015. The world of food allergy research continues to rapidly accelerate, with increasing numbers of outstanding submissions to the Journal. In 2015, important studies on the epidemiology of food allergy were published, suggesting differential rates of food allergy in specific racial and ethnic groups. Even more importantly, studies were published identifying specific risk factors for the development of peanut allergy, as well as specific prevention strategies. We also saw new studies on the diagnosis of food allergy and potential approaches to the treatment of food allergy, as well as novel mechanistic studies helping to explain the immunologic correlates of food allergy and food desensitization. Copyright © 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  5. European Mixed Forests: definition and research perspectives

    Directory of Open Access Journals (Sweden)

    Andres Bravo-Oviedo

    2014-12-01

    Full Text Available Aim of study: We aim at (i developing a reference definition of mixed forests in order to harmonize comparative research in mixed forests and (ii review the research perspectives in mixed forests.Area of study: The definition is developed in Europe but can be tested worldwide.Material and Methods: Review of existent definitions of mixed forests based and literature review encompassing dynamics, management and economic valuation of mixed forests.Main results: A mixed forest is defined as a forest unit, excluding linear formations, where at least two tree species coexist at any developmental stage, sharing common resources (light, water, and/or soil nutrients. The presence of each of the component species is normally quantified as a proportion of the number of stems or of basal area, although volume, biomass or canopy cover as well as proportions by occupied stand area may be used for specific objectives. A variety of structures and patterns of mixtures can occur, and the interactions between the component species and their relative proportions may change over time.The research perspectives identified are (i species interactions and responses to hazards, (ii the concept of maximum density in mixed forests, (iii conversion of monocultures to mixed-species forest and (iv economic valuation of ecosystem services provided by mixed forests.Research highlights: The definition is considered a high-level one which encompasses previous attempts to define mixed forests. Current fields of research indicate that gradient studies, experimental design approaches, and model simulations are key topics providing new research opportunities.Keywords: COST Action; EuMIXFOR; mixed-species forests; admixtures of species.

  6. Proceedings of the European Research Reactor Conference - RRFM 2013 Transactions

    International Nuclear Information System (INIS)

    2013-01-01

    In 2013 RRFM, the European Research Reactor Conference is jointly organised by ENS and Atomexpo LLC. This time the Research Reactor community meet in St. Petersburg, Russia. The conference programme will revolve around a series of Plenary Sessions dedicated to the latest global developments with regards to research reactor technology and management. Parallel sessions will focus on all areas of the Fuel Cycle of Research Reactors, their Utilisation, Operation and Management as well as specific research projects and innovative methods in research reactor analysis and design. In 2013 the European Research Reactor Conference will for the first time give special attention to complementary safety assessments of Research Reactors, following the Fukushima-Dai-Ichi NPP's Accident. (authors)

  7. European network for research in global change (ENRICH)

    Energy Technology Data Exchange (ETDEWEB)

    Ghazi, A [European Commission, Bruxelles (Belgium). DG XII/JRC

    1996-12-31

    While approaching the beginning of the twenty first century, the scientific community is faced with the formidable tasks of monitoring and detecting, understanding and predicting changes in the Earth System and its interactions with human beings. A crucial challenge is to make scientific research results accessible and usable for those involved in the decision making process related to the concept of Sustainable Development. Major international scientific programmes under the umbrella of ICSU, such as the IGBP and WCRP, are dealing with these issues. Although there exist many well developed global change research programmes in several European countries and effective collaboration networks between research institutes, there is an urgent need for overall communication with a view to promoting wider international links ensuring complementarity, synergy and coherence. Recognizing the importance of promoting coherence in research and utilising research results for various European Union (EU) policies, the European Commissioner responsible for Science, Research and Development wrote in March 1992 to all the EU Research Ministers to propose an initiative in this domain. In a rapid response, a group of Senior Experts from the EU Member States was set up in April 1992. This Group established a Task Force to develop the concept of the European Network for Research In Global CHange (ENRICH) which was approved in July 1993

  8. CMS Virtual Visits @ European Researchers Night, 30 September 2016

    CERN Multimedia

    Lapka, Marzena

    2016-01-01

    CMS hosted four virtual visits during European Researchers Night. Audience from Greece (NCRS Demokritos, Athens), Poland (University of Science and Technology in Krakow), Italy (Psiquadro in Perugia & INFN in Pisa) and Portugal (Planetarium Calouste Gulbenkian, organised by LIP) had an occasion to converse with CMS researchers and "virtually" visit CMS Control Room and underground facilities.

  9. European network for research in global change (ENRICH)

    Energy Technology Data Exchange (ETDEWEB)

    Ghazi, A. [European Commission, Bruxelles (Belgium). DG XII/JRC

    1995-12-31

    While approaching the beginning of the twenty first century, the scientific community is faced with the formidable tasks of monitoring and detecting, understanding and predicting changes in the Earth System and its interactions with human beings. A crucial challenge is to make scientific research results accessible and usable for those involved in the decision making process related to the concept of Sustainable Development. Major international scientific programmes under the umbrella of ICSU, such as the IGBP and WCRP, are dealing with these issues. Although there exist many well developed global change research programmes in several European countries and effective collaboration networks between research institutes, there is an urgent need for overall communication with a view to promoting wider international links ensuring complementarity, synergy and coherence. Recognizing the importance of promoting coherence in research and utilising research results for various European Union (EU) policies, the European Commissioner responsible for Science, Research and Development wrote in March 1992 to all the EU Research Ministers to propose an initiative in this domain. In a rapid response, a group of Senior Experts from the EU Member States was set up in April 1992. This Group established a Task Force to develop the concept of the European Network for Research In Global CHange (ENRICH) which was approved in July 1993

  10. European Academy of Allergy and Clinical Immunology task force report on 'dose-response relationship in allergen-specific immunotherapy'.

    Science.gov (United States)

    Calderón, M A; Larenas, D; Kleine-Tebbe, J; Jacobsen, L; Passalacqua, G; Eng, P A; Varga, E M; Valovirta, E; Moreno, C; Malling, H J; Alvarez-Cuesta, E; Durham, S; Demoly, P

    2011-10-01

    For a century, allergen-specific immunotherapy (SIT) has proven to be an effective treatment for allergic rhinitis, asthma, and insect sting allergy. However, as allergen doses are frequently adapted to the individual patient, there are few data on dose-response relationship in SIT. Allergen products for SIT are being increasingly required to conform to regulatory requirements for human medicines, which include the need to demonstrate dose-dependent effects. This report, produced by a Task Force of the EAACI Immunotherapy Interest Group, evaluates the currently available data on dose-response relationships in SIT and aims to provide recommendations for the design of future studies. Fifteen dose-ranging studies fulfilled the inclusion criteria and twelve reported a dose-response relationship for clinical efficacy. Several studies also reported a dose-response relationship for immunological and safety endpoints. Due to the use of different reference materials and methodologies for the determination of allergen content, variations in study design, and choice of endpoints, no comparisons could be made between studies and, as a consequence, no general dosing recommendations can be made. Despite recently introduced guidelines on the standardization of allergen preparations and study design, the Task Force identified a need for universally accepted standards for the measurement of allergen content in SIT preparations, dosing protocols, and selection of clinical endpoints to enable dose-response effects to be compared across studies. © 2011 John Wiley & Sons A/S.

  11. Perspectives for food research and European collaboration in the European Research Area and the new Framework Programme.

    Science.gov (United States)

    Breslin, L

    2001-08-01

    Since 1987, successive framework programmes have contributed to strengthen European food research through the establishment of networks between research institutions, universities and companies from various European countries. In the FAIR programme (1994-1998), 118 research projects comprising nearly 1,000 participants from the European Union and Associated States have been supported in the food area with a European funding of about [symbol: see text] 108 million. Within the Quality of Life and Management of Living Resources programme (1998-2002), food research is mostly supported within the key action 'food, nutrition and health' with a budget of [symbol: see text] 290 million. After the first four deadlines, 735 eligible research proposals have already been received. Further to their evaluation by a panel of independent experts, 108 proposals have been funded or selected for funding representing a total contribution of about [symbol: see text] 168 million. Among those, several clusters of projects are now running on important topics such as probiotics, coeliac diseases, mycotoxins, GMO, safety and food for the elderly. In addition, technology stimulation measures are largely benefiting SMEs to foster their innovation potential. In January 2000, the European Commission adopted a Communication entitled "Towards the European Research Area (ERA)" with the objective to contribute to developing better framework conditions for research in Europe. On 21 February 2001, the Commission adopted proposals to be submitted to the European Parliament and Council for the next framework programme for research and innovation (2002-2006). The new framework programme that is becoming one of the financial instruments of the ERA aims at catalysing the integration of European research by: strengthening of links between the Community research effort and national and regional research policies; concentrating on a limited number of priority fields or research to which activities at the

  12. Beryllium allergy

    International Nuclear Information System (INIS)

    Schoenherr, S.; Pevny, I.

    1989-12-01

    Beryllium is not only a high potent allergen, but also a fotoallergen and can provoke contact allergic reactions, fotoallergic reactions, granulomatous skin reactions, pulmonary granulomatous diseases and sometimes even systemic diseases. The authors present 9 own cases of a patch test positive beryllium allergy, 7 patients with relevant allergy and 5 patients with an allergic contact stomatitis. (author)

  13. Forty years of European Society for Muscle Research

    Directory of Open Access Journals (Sweden)

    Marcus C. Schaub

    2010-09-01

    Full Text Available The European Muscle Club was founded 1971 and since 1972 yearly muscle conferences were held in turn in different European countries. Regular scientific meetings in the field of muscle research did not exist before. The name of the Muscle Club was 1988 changed to European Society for Muscle Research (ESMR. The yearly meetings usually attract 200-300 participants. The 39th meeting will be held 11-15 Sept. 2010 in Abano Terme near Padova, and the 40th meeting 14-18 Sept. 2011 in Berlin. Since 1980 the meeting reports and abstracts are regularly published in the Journal of Muscle Research and Cell Motility (JMRCM. The history of the society and the muscle scientists involved with it will be outlined.

  14. Hazelnut allergy

    DEFF Research Database (Denmark)

    Ortolani, Claudio; Ballmer-Weber, Barbara K; Hansen, Kirsten Skamstrup

    2000-01-01

    Background: Tree nuts are a common cause of food allergy in Europe. However, few studies deal with real food allergy to hazelnuts in subjects believed to be allergic to this food. Objective: We sought to select subjects with a history of allergic reactions on ingestion of hazelnut and determine how...... many of these have true allergy by means of the double-blind, placebo- controlled food challenge (DBPCFC). Methods: Eighty-six subjects with a history of symptoms after hazelnut ingestion were recruited from 3 allergy centers (Milan, Zurich, and Copenhagen). All subjects underwent skin prick tests...... (SPTs) with aeroallergens and hazelnut, as well as having their specific hazelnut IgE levels determined. Diagnosis of clinical relevant food allergy was made on the basis of the DBPCFC. Results: Sixty-seven (77.9%) of 86 subjects had a positive DBPCFC result; 8 were placebo responders, and 11 were...

  15. 4DH Research In A European Context

    DEFF Research Database (Denmark)

    Connolly, David; Mathiesen, Brian Vad; Lund, Henrik

    District heating is essential to achieve a fossil free society in Denmark and the EU. 4DH is an international research centre which develops 4th Generation District Heating Technologies and Systems (www.4dh.dk). In 4DH synergies are created between 1) Grids and components for low temperature...... district heating, 2) Analyses of production and system integration, and 3) Tools and methodologies for planning and implementation. With lower and more flexible distribution lower temperatures renewable energy sources can be utilized, while cost effectively meeting the requirements of low-energy buildings...... and energy conservation measures in the existing building stock. In Heat Roadmap Europe, the principals developed under the 4DH project have been applied at an EU level to demonstrate how district heating can reduce the cost of a low-carbon EU energy system by €100 billion per year (www.heatroadmap.eu)....

  16. EUROPEAN FUNDING - IMPACT ON RESEARCH CAPACITY IN CROATIA

    Directory of Open Access Journals (Sweden)

    Vesna Kotarski

    2016-10-01

    Full Text Available Limited national budgetary resources for R&D in period from 2007 to 2013 imposed a need for Croatian researchers to apply for European research grants. A challenge for effective absorption of European Structural and Investment Funds in the period 2014 to 2020, highlight a need to assess the impact of this external funding on research capacity in Croatia in 2007-2013 period. Qualitative interviews with grant recipients from Ruder Boskovic Institute revealed intangible achievements in terms of research career, enhanced interaction and knowledge transfer to business community, improved research management competences and possibilities for collaboration with internationally recognized research teams. Similar results from studies carried out in other countries indicates the importance of intangible achievements of research grants, which are becoming more and more relevant in the context of public policies (networking, cooperation, strategic planning, knowledge management. The use of EU funds is an extremely complex process which requires a change of approach to the use of public funds and the introduction of the principle of transparency of procedures for all stakeholders in the process, equal access to information and sound financial management. Weaknesses of the Croatian scientific system and absence of will to support excellent research through competitive funding present real threats to successful participation of Croatian researchers in the European framework programs and other external research funding programs. Findings of the study provide valuable insight for national authorities in terms of effective management of national research and innovation programs while maximizing the potential impact of EU funds allocated.

  17. Scintilla European project, the successful research results

    Energy Technology Data Exchange (ETDEWEB)

    Sannie, G.; Kondrasov, V.; Corre, G.; Boudergui, K.; Perot, B.; Carasco, C.; Montemont, G. [Commissariat a l' energie atomique et aux energies alternatives, Saclay, Cadarache, Grenoble (France); Peerani, P.; Carrapico, C.; Tomanin, A.; Rosas, F.; Caviglia, M.; Eklund, G.; Tagziria, H. [European Commission, Joint Research Centre, ITU, Nuclear Security Unit, Ispra (Italy); Friedrich, H.; Chmel, S. [Fraunhofer-Institut fuer Naturwissenschaftlich - Technische Trendanalysen - INT, Euskirchen (Germany); De Vita, R.; Manchini, E.; Pavan, M. [Istituto Nazionale di Fisica Nucleare, Sezione di Genova, Genova (Italy); Grattarola, M.; Botta, E. [Ansaldo Nucleare S.P.A, Genova (Italy); Kovacs, A.; Lakosi, L. [Hungarian Academy of Sciences, Centre for Energy Research, Budapest (Hungary); Baumhauer, C.; Deheuninck, T.; Haddad, E. [ARTTIC, Paris (France); Petrossian, G.; Ferragut, A. [SAPHYMO, Massy (France); Dermody, G.; Crossingham, G. [Symetrica Security Ltd, Southampton (United Kingdom)

    2015-07-01

    The Scintilla FP7 project is ended in December 2014, the fruitful results of 3 years development and tests will be presented. SCINTILLA offers the capacity to finding a reliable alternative to Helium-3 based detection systems since the gas which is predominantly used in nuclear safeguards and security applications has now become very expensive, rare and nearly unavailable. SCINTILLA benchmarks results are based on international standards. Radiation Portal tests were carried out at the Joint Research Centre (JRC) in Ispra (Italy). The scintilla project addresses few mains issues. The first is to develop neutron detectors for Radiation Portal Monitor (RPM) and the second is the need of new wearable integrated solutions for Spectrometric Personal Radiation Monitor (SPRM). The partners which provide technical systems of the scintilla project are INFN-ANSALDO, CEA, SYMETRICA and SAPHYMO. For RPM, the objective is to find reliable alternatives to Helium-3 historical neutron detector and provide technical solutions which cope with tests for reliable mobile and cost effective. For Spectrometric Personal Radiation Monitor (SPRM), SCINTILLA is innovating in technology areas that offer complementary capabilities for detecting and identifying gamma, Two CZT (Cadmium Zinc Telluride) addressing contexts of used by first responder technologies, one is a wearable detector and the second is a gamma camera complemented by advanced image processing technologies. (authors)

  18. Nut and Peanut Allergy

    Science.gov (United States)

    ... 2014 More on this topic for: Teens Shellfish Allergy Food Allergies and Travel My Friend Has a Food Allergy. How Can I Help? My Girlfriend Has a ... for an Allergy Emergency Serious Allergic Reactions (Anaphylaxis) Food Allergies Egg Allergy Allergy Testing View more About Us ...

  19. European research agenda for career guidance and counselling

    DEFF Research Database (Denmark)

    Weber, Peter C.; Katsarov, Johannes; Cohen-Scali, Valérie

    2018-01-01

    In a changing world, there is a need to reflect about the research basis of career guidance and counselling (CGC) as a professional practice, considering the contributions of various disciplines and research traditions. This paper outlines a possible European research agenda (ERA) to further...... enhance the knowledge foundation of the CGC practice. The proposed lines of research, which are pronounced in the ERA, are based on a literature review involving 45 researchers concerned with the CGC practice. At three events, approximately 150 researchers from across Europe were engaged in the discussion...

  20. European research and development strategy for clean power

    International Nuclear Information System (INIS)

    Linkohr, R.

    2006-01-01

    We need more rather than less money for research, energy research in particular, research being an important contributor to progress, in order to achieve peak performance, comply with the quest for knowledge about the structure of the world, or to be able to further improve our quality of life at far less expense of materials and energy. This latter concept is in line with European identity. If we succeed in demonstrating to the world that people can live a better life if they manage their affairs sustainably, we Europeans will have won a new trademark: a sustainable Europe which can be left to future generations. For this purpose Europeans, more than before, must perceive Europe as a space of knowledge. Science policy must be geared to Europe, not just to a national territory. Also, Europe should devote more attention to fundamental research. Some outstanding projects are needed, particularly in energy research, with the participation of industry in order to reduce materials consumption and avoid emissions. Education, too, must be given much attention. In the absence of enthusiastic young scientists, engineers, and skilled workers who know their neighboring countries and their technologies and languages from an early age, European energy policy is bound to remain fragmented. (orig.)

  1. European community light water reactor safety research projects. Experimental issue

    International Nuclear Information System (INIS)

    1975-01-01

    Research programs on light water reactor safety currently carried out in the European Community are presented. They cover: accident conditions (LOCA, ECCS, core meltdown, external influences, etc...), fault and accident prevention and means of mitigation, normal operation conditions, on and off site implications and equipment under severe accident conditions, and miscellaneous subjects

  2. Drug allergies

    Science.gov (United States)

    Allergic reaction - drug (medication); Drug hypersensitivity; Medication hypersensitivity ... A drug allergy involves an immune response in the body that produces an allergic reaction to a medicine. The first time ...

  3. Egg Allergy

    Science.gov (United States)

    ... with eggs. Prevention is the name of the game with food allergies, so it's important for kids ... protein from other foods. Some good ones are meat, poultry, fish, and legumes (beans and peanuts). If ...

  4. Milk Allergy

    Science.gov (United States)

    ... contain blood Abdominal cramps Runny nose Watery eyes Colic, in babies Milk allergy or milk intolerance? A ... fat milk, skim milk, buttermilk Butter Yogurt Ice cream, gelato Cheese and anything that contains cheese Half- ...

  5. European meteorological data: contribution to research, development, and policy support

    Science.gov (United States)

    Biavetti, Irene; Karetsos, Sotiris; Ceglar, Andrej; Toreti, Andrea; Panagos, Panos

    2014-08-01

    The Joint Research Centre of the European Commission has developed Interpolated Meteorological Datasets available on a regular 25x25km grid both to the scientific community and the general public. Among others, the Interpolated Meteorological Datasets include daily maximum/minimum temperature, cumulated daily precipitation, evapotranspiration and wind speed. These datasets can be accessed through a web interface after a simple registration procedure. The Interpolated Meteorological Datasets also serve the Crop Growth Monitoring System (CGMS) at European level. The temporal coverage of the datasets is more than 30 years and the spatial coverage includes EU Member States, neighboring European countries, and the Mediterranean countries. The meteorological data are highly relevant for the development, implementation and assessment of a number of European Union (EU) policy areas: agriculture, soil protection, environment, agriculture, food security, energy, climate change. An online user survey has been carried out in order to assess the impact of the Interpolated Meteorological Datasets on research developments. More than 70% of the users have used the meteorological datasets for research purposes and more than 50% of the users have used those sources as main input for their models. The usefulness of the data scored more than 70% and it is interesting to note that around 25% of the users have published their scientific outputs based on the Interpolated Meteorological Datasets. Finally, the user feedback focuses mostly on improving the data distribution process as well as the visibility of the web platform.

  6. Food allergy

    OpenAIRE

    Waserman Susan; Watson Wade

    2011-01-01

    Abstract Food allergy is defined as an adverse immunologic response to a dietary protein. Food-related reactions are associated with a broad array of signs and symptoms that may involve many bodily systems including the skin, gastrointestinal and respiratory tracts, and cardiovascular system. Food allergy is a leading cause of anaphylaxis and, therefore, referral to an allergist for appropriate and timely diagnosis and treatment is imperative. Diagnosis involves a careful history and diagnost...

  7. Research Design in the study of the European Neighbourhood Policy

    DEFF Research Database (Denmark)

    Exadaktylos, Theofanis; Lynggaard, Kennet

    2017-01-01

    This chapter deals with the pitfalls and pathways of research design aimed at the study of the European Neighbourhood Policy (ENP) and maps out the literature on questions of knowledge ambition, research ontology and epistemology, and choices of approaches to the research object. We include...... a review of traditional research designs in ENP research, through a systematic meta-analysis of a selection of the most-cited articles on the ENP. Inspired by earlier work on awareness of research design in EU studies, ENP research is categorised according to typical choices of research design in the form...... of dichotomous trade-offs. The chapter then discusses how individual contributions to this volume deal with research design challenges of the past and present innovative ways of studying the revised ENP....

  8. Observations on European Education and Educational Research: The "European Educational Research Journal" at Work, 2002-2014

    Science.gov (United States)

    Lindblad, Sverker

    2014-01-01

    This is a review of the "European Educational Research Journal" ("EERJ") since the start in 2002 and up to 2014. Three questions were put forward: what are the ambitions with the journal, how has the journal developed over time, and what are its possible futures? The review is based on minutes and emails from the late 1990s up…

  9. Assessing quality in European educational research indicators and approaches

    CERN Document Server

    Åström, Fredrik; Hansen, Antje

    2014-01-01

    Competition-based models for research policy and management have an increasing influence throughout the research process, from attracting funding to publishing results. The introduction of quality control methods utilizing various forms of performance indicators is part of this development. The authors presented in this volume deal with the following questions: What counts as ‘quality’ and how can this be assessed? What are the possible side effects of current quality control systems on research conducted in the European Research Area, especially in the social sciences and the humanities?

  10. Increasing European Support for Neglected Infectious Disease Research

    Directory of Open Access Journals (Sweden)

    Ole F. Olesen

    Full Text Available Neglected infectious diseases (NIDs are a persistent cause of death and disability in low-income countries. Currently available drugs and vaccines are often ineffective, costly or associated with severe side-effects. Although the scale of research on NIDs does not reflect their disease burden, there are encouraging signs that NIDs have begun to attract more political and public attention, which have translated into greater awareness and increased investments in NID research by both public and private donors. Using publicly available data, we analysed funding for NID research in the European Union's (EU's 7th Framework Programme for Research and Technological Development (FP7, which ran from 2007 to 2013. During FP7, the EU provided €169 million for 65 NID research projects, and thereby placed itself among the top global funders of NID research. Average annual FP7 investment in NID research exceeded €24 million, triple that committed by the EU before the launch of FP7. FP7 NID projects involved research teams from 331 different institutions in 72 countries on six continents, underlining the increasingly global nature of European research activities. NID research has remained a priority in the current EU Framework Programme for research and innovation, Horizon 2020, launched in 2014. This has most notably been reflected in the second programme of the European & Developing Countries Clinical Trials Partnership (EDCTP, which provides unprecedented opportunities to advance the clinical development of new medical interventions against NIDs. Europe is thus better positioned than ever before to play a major role in the global fight against NIDs.

  11. Allergies and Hay Fever

    Science.gov (United States)

    ... ENTCareers Marketplace Find an ENT Doctor Near You Allergies and Hay Fever Allergies and Hay Fever Patient ... life more enjoyable. Why does the body develop allergies? Allergy symptoms appear when the immune system reacts ...

  12. Do Allergies Cause Asthma?

    Science.gov (United States)

    ... for Educators Search English Español Do Allergies Cause Asthma? KidsHealth / For Parents / Do Allergies Cause Asthma? Print ... son la causa del asma? Do Allergies Cause Asthma? Allergies don't cause asthma. But kids who ...

  13. Medication/Drug Allergy

    Science.gov (United States)

    ... Training Home Conditions Medication/Drug Allergy Medication/Drug Allergy Make an Appointment Find a Doctor Ask a ... risk for adverse reactions to medications. Facts about Allergies The tendency to develop allergies may be inherited. ...

  14. Allergy Shots (For Parents)

    Science.gov (United States)

    ... Staying Safe Videos for Educators Search English Español Allergy Shots KidsHealth / For Parents / Allergy Shots What's in ... to help a child deal with them. Why Allergy Shots Are Used An allergy occurs when the ...

  15. EUFAR training opportunities to advance European airborne research

    Science.gov (United States)

    Reusen, I.; Brenguier, J.-L.; Brown, P.; Wendish, M.

    2009-04-01

    EUFAR, EUropean Facilities for Airborne Research, is an FP7 project (http://www.eufar.net) funded by the European Commission with 33 partners that aims at providing and improving the access to European airborne facilities (i.e. aircraft, airborne instruments, data processing centres) for researchers in environmental and geo-sciences through Networking Activities, Transnational Access and Joint Research Activities. This paper reports on the training opportunities within EUFAR for European researchers. In EUFAR three types of training opportunities are offered: 1) Participate in training courses (ET-TC) 2) Join an existing field campaign (ET-EC) 3) Participate in the design of a new field campaign (ET-TA), in the frame of EUFAR Transnational Access and tutored by more experienced researchers. During the 4-year EUFAR project (2008-2012), 4 training courses covering the complete chain from acquisition to interpretation of airborne data and images will be organised during spring/summer for early-stage researchers as well as university lecturers (new in FP7 EUFAR) in airborne research. The training courses will have an equal focus on theory and practical training/demonstration and each training course will be accompanied by a "student" airborne field campaign. Participants will be trained by top-class scientists, aircraft and/or instrument operators and each participant will get the opportunity to design his/her own experiment and to participate to that flight experiment. Furthermore, researchers have the opportunity to join an existing field campaign and work with more experienced researchers, aircraft and/or instrument operators. The list of airborne field campaigns open to join and the eligibility criteria, can be consulted at the EUFAR website. Finally, researchers have the opportunity to participate in the design of a new field campaign in the frame of EUFAR Transnational Access (TA). TA provides access to either aircraft or instrumentation that are not otherwise

  16. Patient engagement with research: European population register study.

    Science.gov (United States)

    McKevitt, Christopher; Fudge, Nina; Crichton, Siobhan; Bejot, Yannick; Daubail, Benoît; Di Carlo, Antonio; Fearon, Patricia; Kolominsky-Rabas, Peter; Sheldenkar, Anita; Newbound, Sophie; Wolfe, Charles D A

    2015-12-01

    Lay involvement in implementation of research evidence into practice may include using research findings to guide individual care, as well as involvement in research processes and policy development. Little is known about the conditions required for such involvement. To assess stroke survivors' research awareness, use of research evidence in their own care and readiness to be involved in research processes. Cross sectional survey of stroke survivors participating in population-based stroke registers in six European centres. The response rate was 74% (481/647). Reasons for participation in register research included responding to clinician request (56%) and to 'give something back' (19%); however, 20% were unaware that they were participating in a stroke register. Research awareness was generally low: 57% did not know the purpose of the register they had been recruited to; 73% reported not having received results from the register they took part in; 60% did not know about any research on stroke care. Few participants (7.6%) used research evidence during their consultations with a doctor. The 34% of participants who were interested in being involved in research were younger, more highly educated and already research aware. Across Europe, stroke survivors already participating in research appear ill informed about stroke research. Researchers, healthcare professionals and patient associations need to improve how research results are communicated to patient populations and research participants, and to raise awareness of the relationship between research evidence and increased quality of care. © 2014 John Wiley & Sons Ltd.

  17. Prevalence of food allergies in South Asia.

    Science.gov (United States)

    Arakali, Schweta R; Green, Todd D; Dinakar, Chitra

    2017-01-01

    To evaluate the published medical literature on the prevalence and types of food allergies in South Asia. A PubMed search was performed using the keywords India and food allergy, Asia and food allergy, and South Asia and food allergy for any period. Articles cited in selected studies were reviewed for their appropriateness of inclusion into this review. Publications were included that were original research and fit the topic of food allergy and South Asia. South Asia is defined as region inclusive of India, Pakistan, Bangladesh, and Sri Lanka. A total of 169 articles were initially identified, and 47 were reviewed in detail for inclusion in this review. The primary focus was placed on 10 studies that consisted of case reports of newly reported or documented food allergy, survey studies that investigated food allergy prevalence in specific demographics, and prospective and cross-sectional studies with case controls, all of which investigated food allergy prevalence by allergy testing in a selected population. The medical literature on the prevalence and types of food allergy in South Asia indicates that there is a variety of unusual and unique allergens and an overall low incidence of food allergy. There is also an association of increased food allergy prevalence in individuals who live in metropolitan regions or who migrate to communities that have adopted westernization. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  18. Food Allergy Information

    DEFF Research Database (Denmark)

    2008-01-01

    Developed the content of this website in collaboration with a group of leading allergy experts from the food industry, patient organisations, clinical centres, and research institutions in Europe. This has been undertaken as part of the EuroPrevall project coordinated by Clare Mills at the Instit......Developed the content of this website in collaboration with a group of leading allergy experts from the food industry, patient organisations, clinical centres, and research institutions in Europe. This has been undertaken as part of the EuroPrevall project coordinated by Clare Mills...

  19. European Commission research on aircraft impacts in the atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Amanatidis, G T; Angeletti, G [European Commission (CEC), Brussels (Belgium)

    1998-12-31

    Aircraft engines release in the troposphere and lower stratosphere a number of chemical compounds (NO{sub x}, CO{sub 2}, CO, H{sub 2}O, hydrocarbons, sulphur, soot, etc.) which could potentially affect the ozone layer and the climate through chemical, dynamical and radiative changes. The global amount of gases and particles emitted by current subsonic and projected supersonic aircraft fleets can be estimated, but significant uncertainties remain about the fate of these emissions in the atmosphere. The European efforts concerning these potential atmospheric impacts of aircraft emissions are conducted by the Environment and Climate Research Programme of the European Commission (EC) as well as by national programmes of the Member States of the European Union (EU). The European research activities in this field, are described, divided for practical reasons in two periods. The first includes activities supported under the 3. Framework Programme for R and D activities which covered the period from 1992 up to 1996, while the second period has started in early 1996 and is supported under the 4. Framework Programme. (R.P.) 6 refs.

  20. European Commission research on aircraft impacts in the atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Amanatidis, G.T.; Angeletti, G. [European Commission (CEC), Brussels (Belgium)

    1997-12-31

    Aircraft engines release in the troposphere and lower stratosphere a number of chemical compounds (NO{sub x}, CO{sub 2}, CO, H{sub 2}O, hydrocarbons, sulphur, soot, etc.) which could potentially affect the ozone layer and the climate through chemical, dynamical and radiative changes. The global amount of gases and particles emitted by current subsonic and projected supersonic aircraft fleets can be estimated, but significant uncertainties remain about the fate of these emissions in the atmosphere. The European efforts concerning these potential atmospheric impacts of aircraft emissions are conducted by the Environment and Climate Research Programme of the European Commission (EC) as well as by national programmes of the Member States of the European Union (EU). The European research activities in this field, are described, divided for practical reasons in two periods. The first includes activities supported under the 3. Framework Programme for R and D activities which covered the period from 1992 up to 1996, while the second period has started in early 1996 and is supported under the 4. Framework Programme. (R.P.) 6 refs.

  1. [Allergy - an environmental disease].

    Science.gov (United States)

    Traidl-Hoffmann, Claudia

    2017-06-01

    The increase in allergies is a phenomenon that is being observed in all fast-developing countries. For a long time, science has taken as a starting point that solely a genetic predisposition is a precondition for the development of an allergy. Today, knowledge of environmental factors that can alter genes or the transcription of genes in the cells, has improved. Epidemiological studies have meanwhile identified several environmental factors that have a protective or supporting effect on allergy development. The environmental microbiome has recently gained central interest. A common theme in most of the studies is diversity: reduced diversity is correlated with enhanced risk for chronic inflammatory diseases and allergy.It is now of great interest for research to further analyze such environment-gene and/or environment-human interactions on all levels - from organs to cells to small and microstructures such as genes. For immunologists, it is specifically about understanding the influencing factors and effector pathways of allergens, and to apply thereby obtained insights in the follow-up for the ultimate goal of allergy research - prevention.

  2. Changing governance of research and technology policy : The European research area

    NARCIS (Netherlands)

    Edler, Jakob; Kuhlmann, Stefan; Behrens, Maria

    2003-01-01

    This collection analyses and comments on the development of the ERA, which seeks to coordinate national research and advance European wide projects. The contributors include leading scholars of European integration and technology policy and high-level administrators. They discuss the potential

  3. Euratom research and training in nuclear reactor safety: Towards European research and the higher education area

    International Nuclear Information System (INIS)

    Goethem, G. van

    2004-01-01

    In this invited lecture, research and training in nuclear fission are looked at from a European perspective with emphasis on the three success factors of any European policy, namely: common needs, vision and instruments, that ought to be strongly shared amongst the stakeholders across the Member States concerned. As a result, the following questions are addressed: What is driving the current EU trend towards more research, more education and more training, in general? Regarding nuclear fission, in particular, who are the end-users of Euratom 'research and training' and what are their expectations from EU programmes? Do all stakeholders share the same vision about European research and training in nuclear fission? What are the instruments proposed by the European Commission (EC) to conduct joint research programmes of common interest for the nuclear fission community? In conclusion, amongst the stakeholders in Europe, there seems to be a wide consensus about common needs and instruments, but not about a common vision regarding nuclear. (author)

  4. Stepping up Open Science Training for European Research

    Directory of Open Access Journals (Sweden)

    Birgit Schmidt

    2016-06-01

    Full Text Available Open science refers to all things open in research and scholarly communication: from publications and research data to code, models and methods as well as quality evaluation based on open peer review. However, getting started with implementing open science might not be as straightforward for all stakeholders. For example, what do research funders expect in terms of open access to publications and/or research data? Where and how to publish research data? How to ensure that research results are reproducible? These are all legitimate questions and, in particular, early career researchers may benefit from additional guidance and training. In this paper we review the activities of the European-funded FOSTER project which organized and supported a wide range of targeted trainings for open science, based on face-to-face events and on a growing suite of e-learning courses. This article reviews the approach and experiences gained from the first two years of the project.

  5. Multidisciplinary European Low Dose Initiative (MELODI). Strategic research agenda for low dose radiation risk research

    Energy Technology Data Exchange (ETDEWEB)

    Kreuzer, M. [Federal Office for Radiation Protection, BfS, Department of Radiation Protection and Health, Neuherberg (Germany); Auvinen, A. [University of Tampere, Tampere (Finland); STUK, Helsinki (Finland); Cardis, E. [ISGlobal, Barcelona Institute for Global Health, Barcelona (Spain); Durante, M. [Institute for Fundamental Physics and Applications, TIFPA, Trento (Italy); Harms-Ringdahl, M. [Stockholm University, Centre for Radiation Protection Research, Stockholm (Sweden); Jourdain, J.R. [Institute for Radiological Protection and Nuclear Safety, IRSN, Fontenay-aux-roses (France); Madas, B.G. [MTA Centre for Energy Research, Environmental Physics Department, Budapest (Hungary); Ottolenghi, A. [University of Pavia, Physics Department, Pavia (Italy); Pazzaglia, S. [Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Rome (Italy); Prise, K.M. [Queens University Belfast, Belfast (United Kingdom); Quintens, R. [Belgian Nuclear Research Centre, SCK-CEN, Mol (Belgium); Sabatier, L. [French Atomic Energy Commission, CEA, Paris (France); Bouffler, S. [Public Health England, PHE, Chilton (United Kingdom)

    2018-03-15

    MELODI (Multidisciplinary European Low Dose Initiative) is a European radiation protection research platform with focus on research on health risks after exposure to low-dose ionising radiation. It was founded in 2010 and currently includes 44 members from 18 countries. A major activity of MELODI is the continuous development of a long-term European Strategic Research Agenda (SRA) on low-dose risk for radiation protection. The SRA is intended to identify priorities for national and European radiation protection research programs as a basis for the preparation of competitive calls at the European level. Among those key priorities is the improvement of health risk estimates for exposures close to the dose limits for workers and to reference levels for the population in emergency situations. Another activity of MELODI is to ensure the availability of European key infrastructures for research activities, and the long-term maintenance of competences in radiation research via an integrated European approach for training and education. The MELODI SRA identifies three key research topics in low dose or low dose-rate radiation risk research: (1) dose and dose rate dependence of cancer risk, (2) radiation-induced non-cancer effects and (3) individual radiation sensitivity. The research required to improve the evidence base for each of the three key topics relates to three research lines: (1) research to improve understanding of the mechanisms contributing to radiogenic diseases, (2) epidemiological research to improve health risk evaluation of radiation exposure and (3) research to address the effects and risks associated with internal exposures, differing radiation qualities and inhomogeneous exposures. The full SRA and associated documents can be downloaded from the MELODI website (http://www.melodi-online.eu/sra.html). (orig.)

  6. Radiation research within the framework programmes of the European Commission

    Energy Technology Data Exchange (ETDEWEB)

    Karaoglou, A.; Kelly, G.N.; Desmet, G.; Menzel, H.G.; Schibilla, H.; Olast, M.; Gasperini, F.; Chadwick, K.H.; Sinnave, J. [European Commission Directorate General science, Brussels (Belgium). Research and Development, Radiation Protection Research Action

    1997-09-01

    The background to the radiation protection research and training programme of the European Commission is described in the presentation. The objectives and achievements of the third framework programme are summarised together with a description of how the achievements led to the establishment of the priorities for the fourth framework programme. Indications on the preliminary prospects for the fifth framework programme, 1998-2002 are also given. (6 refs.).

  7. Welcome from ESARDA (European Safeguards Research and Development Association)

    International Nuclear Information System (INIS)

    Van der Meer, K.

    2015-01-01

    ESARDA, on the one hand being part of that European family and on the other hand working in practice to support peace by the non-proliferation of nuclear weapons, can be considered as a perfect representative of that European peace process. Going now from the European to the global perspective, peace should be our motivating force and this is also expressed in the basis of safeguards: the non-proliferation Treaty. Several articles of the Treaty deal with not developing nuclear weapons and not supporting the development of nuclear weapons by other countries, and one article (Article VI) deals with the general and complete nuclear disarmament. What is ESARDA doing in practice- First we provide a forum to exchange scientific information for the benefit of all safeguards stakeholders. The most important forum is the biannual open ESARDA safeguards symposium that will be held next year from 19-21 May in Manchester. Next to the ESARDA symposia, we coordinate European safeguards research via our ESARDA Working Groups. Also non-members are welcome in these WG as observers. JRC Ispra maintains the ESARDA website that also supports exchange of safeguards information

  8. Globalisation and allergy.

    Science.gov (United States)

    Castelain, Michel

    2011-01-01

    Globalisation brings patients more and more into contact with products or food from other cultures or countries. Europeans may be confronted with allergens not yet known in Europe - such as dimethylfumarate - responsible for contact allergy epidemics. Moreover, "low cost" goods, not always legally imported into Europe, sometimes may lead to European legislation being circumvented and thus bring our patients into contact with components that have been banned from manufacturing processes or strongly regulated, such as nickel in jewelry or telephones, some colouring agents in clothes or preservatives in cosmetics. Disinfection measures for freight containers arriving from other continents into our harbours lead to fumigants and other toxic products contaminating the air and the transported products or goods. Globalisation can not only elicit contact allergy but also airborne contact dermatitis or food allergy. The aim of this paper is not to make an exhaustive review of cutaneous allergic problems elicited by globalisation, but to illustrate this new worldwide problem with a few meaningful examples.

  9. Chromium allergy

    DEFF Research Database (Denmark)

    Hansen, M B; Johansen, J D; Menné, Torkil

    2003-01-01

    Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr(VI)-sensitive ......Most studies investigating chromium allergy have been performed with Cr(VI). However, real exposure to chromium from leather products includes both Cr(III) and Cr(VI). We have determined and compared the minimum elicitation threshold (MET) concentration for Cr(III) and Cr(VI) in Cr......(III) was concluded to play an important role in chromium allergy, because Cr(III) and Cr(VI) were both capable of eliciting eczema at low concentrations. Rather than regarding chromium dermatitis as a result of Cr(VI) allergy alone, it may be more correct to consider it as a result of a combined Cr(III) and Cr......(VI) allergy....

  10. Eastern European Political Socialization Modeling Research: A Literature Review

    Directory of Open Access Journals (Sweden)

    Camelia Florela Voinea

    2014-01-01

    Full Text Available This paper presents empirical modeling research on political socialization of the citizens in the new Eastern European democracies. The political socialization issue offers a comparative perspective over the modeling methodologies in analytical paradigms. Eastern European political culture research has revealed features of the electoral behavior and political participation which can be identified in different degrees in all the new democracies in the area: passivity with respect to political activity of parties, elites and institutions, political apathy or lack of reaction to anti-democratic actions, skepticism or distrust in institutions, scarce participation to social movements. Several authors explain the actual political behavior of the Eastern European citizens’ and their low social and political involvement by the (political culture heritage of the communist regimes in which they lived for a long time, and which keeps shaping their political attitudes towards the state, civil society, government and institutions. Research issues in the analysis of political participation are traditionally based on statistics analyses of empirical evidence coming from public surveys. However, scarcity ofempirical data from the communist periode with regard to (political socialization, values and beliefs represent a major obstacle towards a better understanding of the historical roots of current behaviors and attitudes. Scarcity of observational data might be overcome by computational and simulation modeling.

  11. European Network of Bipolar Research Expert Centre (ENBREC)

    DEFF Research Database (Denmark)

    Henry, Chantal; Andreassen, Ole A; Barbato, Angelo

    2013-01-01

    Bipolar disorders rank as one of the most disabling illnesses in working age adults worldwide. Despite this, the quality of care offered to patients with this disorder is suboptimal, largely due to limitations in our understanding of the pathology. Improving this scenario requires the development...... centres across Europe can collaborate on a wide range of basic science and clinical programmes using shared protocols. This paper is to describe the network and how it aims to improve the quality and effectiveness of research in a neglected priority area....... of a critical mass of expertise and multicentre collaborative projects. Within the framework of the European FP7 programme, we developed a European Network of Bipolar Research Expert Centres (ENBREC) designed specifically to facilitate EU-wide studies. ENBREC provides an integrated support structure...... facilitating research on disease mechanisms and clinical outcomes across six European countries (France, Germany, Italy, Norway, Spain and the UK). The centres are adopting a standardised clinical assessment that explores multiple aspects of bipolar disorder through a structured evaluation designed to inform...

  12. International Consensus on drug allergy.

    Science.gov (United States)

    Demoly, P; Adkinson, N F; Brockow, K; Castells, M; Chiriac, A M; Greenberger, P A; Khan, D A; Lang, D M; Park, H-S; Pichler, W; Sanchez-Borges, M; Shiohara, T; Thong, B Y- H

    2014-04-01

    When drug reactions resembling allergy occur, they are called drug hypersensitivity reactions (DHRs) before showing the evidence of either drug-specific antibodies or T cells. DHRs may be allergic or nonallergic in nature, with drug allergies being immunologically mediated DHRs. These reactions are typically unpredictable. They can be life-threatening, may require or prolong hospitalization, and may necessitate changes in subsequent therapy. Both underdiagnosis (due to under-reporting) and overdiagnosis (due to an overuse of the term ‘allergy’) are common. A definitive diagnosis of such reactions is required in order to institute adequate treatment options and proper preventive measures. Misclassification based solely on the DHR history without further testing may affect treatment options, result in adverse consequences, and lead to the use of more-expensive or less-effective drugs, in contrast to patients who had undergone a complete drug allergy workup. Several guidelines and/or consensus documents on general or specific drug class-induced DHRs are available to support the medical decision process. The use of standardized systematic approaches for the diagnosis and management of DHRs carries the potential to improve outcomes and should thus be disseminated and implemented. Consequently, the International Collaboration in Asthma, Allergy and Immunology (iCAALL), formed by the European Academy of Allergy and Clinical Immunology (EAACI), the American Academy of Allergy, Asthma and Immunology (AAAAI), the American College of Allergy, Asthma and Immunology (ACAAI), and the World Allergy Organization (WAO), has decided to issue an International CONsensus (ICON) on drug allergy. The purpose of this document is to highlight the key messages that are common to many of the existing guidelines, while critically reviewing and commenting on any differences and deficiencies of evidence, thus providing a comprehensive reference document for the diagnosis and management of

  13. Nickel allergy

    DEFF Research Database (Denmark)

    Fischer, L A; Johansen, J D; Menné, T

    2007-01-01

    BACKGROUND: The frequency of nickel allergy varies between different population groups. Exposure regulation has proven effective in decreasing the frequency. Experimental studies with other allergens have shown a significant relation between patch test reactivity and repeated open application test...... in a patch test and a dilution series of three concentrations in a ROAT, with duration of up to 21 days. Eighteen persons with no nickel allergy were included as control group for the ROAT. RESULTS: The predicted dose which will elicit a reaction in 10% of allergic individuals was calculated to be 0......-response; indeed, there was no statistically significant difference. CONCLUSIONS: For elicitation of nickel allergy the elicitation threshold for the patch test is higher than the elicitation threshold (per application) for the ROAT, but is approximately the same as the accumulated elicitation threshold...

  14. European research school on large scale solar thermal – SHINE

    DEFF Research Database (Denmark)

    Bales, Chris; Forteza, Pau Joan Cortés; Furbo, Simon

    2014-01-01

    The Solar Heat Integration NEtwork (SHINE) is a European research school in which 13 PhD students in solar thermal technologies are funded by the EU Marie-Curie program. It has five PhD course modules as well as workshops and seminars dedicated to PhD students both within the project as well...... as outside of it. The SHINE research activities focus on large solar heating systems and new applications: on district heating, industrial processes and new storage systems. The scope of this paper is on systems for district heating for which there are five PhD students, three at universities and two...

  15. e-EPS News: Consultation on European Research, Innovation & Gender

    CERN Document Server

    e-EPS

    2011-01-01

    e-EPS News is a monthly addition to the CERN Bulletin line-up, showcasing an article by the e-EPS – the European Physical Society newsletter – as part of a new collaboration between the two publications.   EPS members have been invited to take part in a Public Consultation on the Future of Gender and Innovation in Europe. The consultation, which is intended to complement the EC Green Paper ‘From Challenges to Opportunities: Towards a Common Strategic Framework for EU Research and Innovation Funding’, will be published and discussed during the first European Gender Summit in Brussels on 8-9 November this year. It is hoped that the consultation – which is being coordinated by genSET and the organisers of the European Gender Summit – will create a better understanding of how Europe might benefit from a more effective mainstreaming of the gender dimension in research, innovation and scientific systems. Responses from the co...

  16. Fossil fuel power generation within the European Research Area

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-12-10

    The report is the first in a series of three produced by the PowerClean Thematic Network that looks at and defines future requirements for research and development of fossil fuel power generation in the European Union. It makes the case for fossil fuel R & D with emphasis on the need for clean coal technologies (to increased efficiency and other CO{sub 2} capture and storage) For satisfying future energy demands of the enlarged European Union between now and 2030. The report concludes that affirmative R, D and D action is needed to support the EU power industry, working together on a Europe-wide basis, to establish the use of coal and other fossil fuels in near-zero emissions power plant. The role model would be the European Research Area, as in the Sixth Framework Programme (FP6), but with a more comprehensive range of technical objectives recognising the importance of fossil fuels. Section headings are: introduction; current energy use; future needs and requirements; the future for clean fossil fuel energy in Europe; comparison with approaches adopted elsewhere (USA Vision 21 and FutureGen programmes, Japan); and responsibilities for EU coal R, D & D. 14 refs., 9 figs., 4 tabs.

  17. The actual citation impact of European oncological research.

    Science.gov (United States)

    López-Illescas, Carmen; de Moya-Anegón, Félix; Moed, Henk F

    2008-01-01

    This study provides an overview of the research performance of major European countries in the field Oncology, the most important journals in which they published their research articles, and the most important academic institutions publishing them. The analysis was based on Thomson Scientific's Web of Science (WoS) and calculated bibliometric indicators of publication activity and actual citation impact. Studying the time period 2000-2006, it gives an update of earlier studies, but at the same time it expands their methodologies, using a broader definition of the field, calculating indicators of actual citation impact, and analysing new and policy relevant aspects. Findings suggest that the emergence of Asian countries in the field Oncology has displaced European articles more strongly than articles from the USA; that oncologists who have published their articles in important, more general journals or in journals covering other specialties, rather than in their own specialist journals, have generated a relatively high actual citation impact; and that universities from Germany, and--to a lesser extent--those from Italy, the Netherlands, UK, and Sweden, dominate a ranking of European universities based on number of articles in oncology. The outcomes illustrate that different bibliometric methodologies may lead to different outcomes, and that outcomes should be interpreted with care.

  18. European military mental health research: benefits of collaboration.

    Science.gov (United States)

    Himmerich, Hubertus; Willmund, G D; Wesemann, U; Jones, N; Fear, N T

    2017-06-01

    Despite joint participation in international military operations, few collaborative military mental health research projects have been undertaken by European countries. From a common perspective of military mental health researchers from Germany and the UK, the lack of shared research might be related not only to the use of different languages but also the different ways in which the two militaries provide mental health and medical support to operations and differences in military institutions. One area that is suitable for military health research collaboration within UK and German forces is mental health and well-being among military personnel. This could include the study of resilience factors, the prevention of mental disorder, mental health awareness, stigma reduction and the treatment of mental disorder. Military mental health research topics, interests and the studies that have been conducted to date in the UK and Germany have considerable overlap and commonality of purpose. To undertake the investigation of the long-term consequences of operational deployment, the specific burdens placed on military families and to further the understanding of the role of factors such as biomarkers for use in military mental health research, it seems advisable to forge international research alliances across European nations, which would allow for researchers to draw transcultural and generalisable conclusions from their work. Such an enterprise is probably worthwhile given the shared research interests of Germany and the UK and the common perspectives on military mental health in particular. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  19. A framework for measuring the social impact of food allergy across Europe: a EuroPrevall state of the art paper

    NARCIS (Netherlands)

    de Blok, B. M. J.; Vlieg-Boerstra, B. J.; Oude Elberink, J. N. G.; Duiverman, E. J.; DunnGalvin, A.; Hourihane, J. O.'B.; Cornelisse-Vermaat, J. R.; Frewer, L.; Mills, C.; Dubois, A. E. J.

    2007-01-01

    This state of the art paper has been developed through EuroPrevall, a European multicentre research project funded by the European Union which aims to improve quality of life for food allergic individuals. Food allergy (whether clinically diagnosed or self-perceived) represents a major health issue

  20. Food Allergies

    Centers for Disease Control (CDC) Podcasts

    2013-04-23

    In this podcast for kids, the Kidtastics talk about the dangers of food allergies and the need to be aware if any friends or classmates have them.  Created: 4/23/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 4/23/2013.

  1. Methyldibromoglutaronitrile allergy

    DEFF Research Database (Denmark)

    Fischer, L A; Johansen, J D; Menné, T

    2008-01-01

    BACKGROUND: Methyldibromoglutaronitrile (MDBGN) is a preservative, which was approved for use in cosmetics in the mid-1980s. The incidence of allergy to MDBGN rose during the 1990s, but is now decreasing due to regulatory intervention. Experimental studies with other allergens have shown a signif......BACKGROUND: Methyldibromoglutaronitrile (MDBGN) is a preservative, which was approved for use in cosmetics in the mid-1980s. The incidence of allergy to MDBGN rose during the 1990s, but is now decreasing due to regulatory intervention. Experimental studies with other allergens have shown...... to MDBGN were tested with a dilution series of MDBGN in a patch test and a ROAT (duration up to 21 days). Seventeen people with no MDBGN allergy were included as a control group for the ROAT. RESULTS: The response frequency for the ROAT (in microg MDBGN cm(-2) per application) was significantly higher than...... the response frequency for the patch test, while the response frequency for the accumulated ROAT dose, at 1, 2 and 3 weeks was very similar to the patch test response frequency; indeed there was no statistical significant difference. CONCLUSIONS: For elicitation of MDBGN allergy the response frequency...

  2. The European Repository Landscape 2008 Inventory of Digital Repositories for Research Output

    CERN Document Server

    Van der Graaf, Maurits

    2009-01-01

    It is widely acknowledged that a common knowledge base for European research is necessary. Research repositories are an important innovation to the scientific information infrastructure. In 2006, digital repositories in the 27 countries of the European we

  3. Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts.

    Directory of Open Access Journals (Sweden)

    Karin C Lødrup Carlsen

    Full Text Available OBJECTIVE: To examine the associations between pet keeping in early childhood and asthma and allergies in children aged 6-10 years. DESIGN: Pooled analysis of individual participant data of 11 prospective European birth cohorts that recruited a total of over 22,000 children in the 1990s. EXPOSURE DEFINITION: Ownership of only cats, dogs, birds, rodents, or cats/dogs combined during the first 2 years of life. OUTCOME DEFINITION: Current asthma (primary outcome, allergic asthma, allergic rhinitis and allergic sensitization during 6-10 years of age. DATA SYNTHESIS: Three-step approach: (i Common definition of outcome and exposure variables across cohorts; (ii calculation of adjusted effect estimates for each cohort; (iii pooling of effect estimates by using random effects meta-analysis models. RESULTS: We found no association between furry and feathered pet keeping early in life and asthma in school age. For example, the odds ratio for asthma comparing cat ownership with "no pets" (10 studies, 11489 participants was 1.00 (95% confidence interval 0.78 to 1.28 (I(2 = 9%; p = 0.36. The odds ratio for asthma comparing dog ownership with "no pets" (9 studies, 11433 participants was 0.77 (0.58 to 1.03 (I(2 = 0%, p = 0.89. Owning both cat(s and dog(s compared to "no pets" resulted in an odds ratio of 1.04 (0.59 to 1.84 (I(2 = 33%, p = 0.18. Similarly, for allergic asthma and for allergic rhinitis we did not find associations regarding any type of pet ownership early in life. However, we found some evidence for an association between ownership of furry pets during the first 2 years of life and reduced likelihood of becoming sensitized to aero-allergens. CONCLUSIONS: Pet ownership in early life did not appear to either increase or reduce the risk of asthma or allergic rhinitis symptoms in children aged 6-10. Advice from health care practitioners to avoid or to specifically acquire pets for primary prevention of asthma or allergic

  4. Spice allergy.

    Science.gov (United States)

    Chen, James L; Bahna, Sami L

    2011-09-01

    To provide a review on spice allergy and its implementation in clinical practice. PubMed searches were performed using spice allergy as the keyword for original and review articles. Selected references were also procured from the reviewed articles' references list. Articles were selected based on their relevance to the topic. Spices are available in a large variety and are widely used, often as blends. Spice allergy seems to be rare, reportedly affecting between 4 and 13 of 10,000 adults and occurring more often in women because of cosmetic use. No figures were available on children. Most spice allergens are degraded by digestion; therefore, IgE sensitization is mostly through inhalation of cross-reacting pollens, particularly mugwort and birch. The symptoms are more likely to be respiratory when exposure is by inhalation and cutaneous if by contact. Studies on skin testing and specific IgE assays are limited and showed low reliability. The diagnosis primarily depends on a good history taking and confirmation with oral challenge. The common use of spice blends makes identifying the particular offending component difficult, particularly because their components are inconsistent. Spices are widely used and contain multiple allergens, yet spice allergy is probably markedly underdiagnosed. There is a need for reliable skin testing extracts and serum specific IgE assays. Currently, the diagnosis depends on a good history taking and well-designed titrated challenge testing. Until immunotherapy becomes developed, treatment is strict avoidance, which may be difficult because of incomplete or vague labeling. Copyright © 2011 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  5. Medical research in emergency research in the European Union member states: tensions between theory and practice.

    Science.gov (United States)

    Kompanje, Erwin J O; Maas, Andrew I R; Menon, David K; Kesecioglu, Jozef

    2014-04-01

    In almost all of the European Union member states, prior consent by a legal representative is used as a substitute for informed patient consent for non-urgent medical research. Deferred (patient and/or proxy) consent is accepted as a substitute in acute emergency research in approximately half of the member states. In 12 European Union member states emergency research is not mentioned in national law. Medical research in the European Union is covered by the Clinical Trial Directive 2001/20/EC. A proposal for a regulation by the European Commission is currently being examined by the European Parliament and the Council and will replace Directive 2001/20/EC. Deferred patient and/or proxy consent is allowed in the proposed regulation, but does not fit completely in the practice of emergency research. For example, deferred consent is only possible when legal representatives are not available. This criterion will delay inclusion of patients in acute life-threatening conditions in short time frames. As the regulation shall be binding in its entirety in all member states, emergency research in acute situations is still not possible as it should be.

  6. Cooperation in research in the European Atomic Energy Community (EURATOM)

    International Nuclear Information System (INIS)

    Marka, Philippe.

    1977-01-01

    This work studies the legal instruments for cooperative research granted to Euratom under the Treaty establishing the European Atomic Energy Community, and the conditions whereby concrete use was made of these instruments. This assessment of Euratom's efforts to launch a community nuclear industry is accompanied by an analysis of the respective roles of the bodies of the Community, the Council and the Commission, as well as of the circumstances which, according to the author, have led to a paralysis of this institution. (NEA) [fr

  7. The basics of spherical tokamaks and progress in European research

    International Nuclear Information System (INIS)

    Gusev, V K; Alladio, F; Morris, A W

    2003-01-01

    When the aspect ratio of a tokamak (A = R/a) decreases significantly, there is a transformation of the well studied tokamak toroidal magnetic configuration into the spherical tokamak (ST) configuration. This configuration has high natural plasma elongation and triangularity and other unique equilibrium and stability properties of ST configuration, which are discussed in this paper. European research into ST physics is well advanced in spite of the young age of this branch of fusion science. An overview of selected experimental and theoretical results obtained at Ioffe, Culham and Frascati is given with the emphasis on their complementarity and links to the main stream of tokamak research, such as ITER. An outline of the basic ST advantages and the potential of ST research for new insights into magnetic confinement is also given. More detailed descriptions of recent advances in ST theory and experiment may be found in the invited papers by Akers and Ono in the proceedings of this conference

  8. Project 'European Research Center for Air Pollution Abatement Measures'

    International Nuclear Information System (INIS)

    1985-04-01

    During the 5-7th of March 1985 the first status report of the project 'European Research Center for Air Pollution Control Measures' took place in the Nuclear Research Center, Karlsruhe. Progress reports on the following topics assessment and analysis of the impacts of airborne pollutants on forest trees; distinction from other potential causes of recent forest dieback, research into atmospheric dispersion, conversion and deposition of airborne pollutants, development and optimization of industrial-technical processes to reduce or avoid emissions and providing instruments and making recommendations to the industrial and political sectors were presented. This volume is a collection of the work reported there. 42 papers were entered separately. (orig./MG) [de

  9. Gender equality observations and actions by the European Research Council

    Science.gov (United States)

    Rydin, Claudia Alves de Jesus; Farina Busto, Luis; Penny, Martin

    2016-04-01

    Women have historically been underrepresented in science. Much positive progress in attracting women to research careers has been achieved in recent years; however, the most influential and high profile positions in most countries are still predominantly occupied by men. The European Research Council (ERC), Europe's premiere funding agency for frontier research, views gender equality as an important challenge. The ERC monitors closely gender figures on every call and has taken actions to tackle gender imbalances and potential unconscious biases. The ERC talk is focused on efforts made to understand and ensure equal treatment of all candidates, with particular focus on gender balance and with specific attention to geosciences. Data and statistics collected from ERC's internationally recognised funding schemes are presented.

  10. European Universities' Guidance on Research Integrity and Misconduct.

    Science.gov (United States)

    Aubert Bonn, Noémie; Godecharle, Simon; Dierickx, Kris

    2017-02-01

    Research integrity is imperative to good science. Nonetheless, many countries and institutions develop their own integrity guidance, thereby risking incompatibilities with guidance of collaborating institutions. We retrieved guidance for academic integrity and misconduct of 18 universities from 10 European countries and investigated accessibility, general content, principles endorsed, and definitions of misconduct. Accessibility and content differ substantially between institutions. There are general trends of common principles of integrity and definitions of misconduct, yet differences remain. Parallel with previous research, we distinguish different approaches in integrity guidance; one emphasizes broad values of integrity, and the other details negative behaviors of misconduct. We propose that a balance between both approaches is necessary to preserve trust, meaning, and realism of guidance on research integrity.

  11. TRANSVAC research infrastructure - Results and lessons learned from the European network of vaccine research and development.

    Science.gov (United States)

    Geels, Mark J; Thøgersen, Regitze L; Guzman, Carlos A; Ho, Mei Mei; Verreck, Frank; Collin, Nicolas; Robertson, James S; McConkey, Samuel J; Kaufmann, Stefan H E; Leroy, Odile

    2015-10-05

    TRANSVAC was a collaborative infrastructure project aimed at enhancing European translational vaccine research and training. The objective of this four year project (2009-2013), funded under the European Commission's (EC) seventh framework programme (FP7), was to support European collaboration in the vaccine field, principally through the provision of transnational access (TNA) to critical vaccine research and development (R&D) infrastructures, as well as by improving and harmonising the services provided by these infrastructures through joint research activities (JRA). The project successfully provided all available services to advance 29 projects and, through engaging all vaccine stakeholders, successfully laid down the blueprint for the implementation of a permanent research infrastructure for early vaccine R&D in Europe. Copyright © 2015. Published by Elsevier Ltd.

  12. Network of Research Infrastructures for European Seismology (NERIES)—Web Portal Developments for Interactive Access to Earthquake Data on a European Scale

    OpenAIRE

    A. Spinuso; L. Trani; S. Rives; P. Thomy; F. Euchner; Danijel Schorlemmer; Joachim Saul; Andres Heinloo; R. Bossu; T. van Eck

    2009-01-01

    The Network of Research Infrastructures for European Seismology (NERIES) is European Commission (EC) project whose focus is networking together seismological observatories and research institutes into one integrated European infrastructure that provides access to data and data products for research. Seismological institutes and organizations in European and Mediterranean countries maintain large, geographically distributed data archives, therefore this scenario suggested a design approach bas...

  13. Prevalence of food allergy/intolerance in Europe

    DEFF Research Database (Denmark)

    Madsen, Charlotte Bernhard

    1997-01-01

    Discussed in this paper is the prevalence of allergy and intolerance to foods in Europe. Prevalence of allergy to food additives is not included. A fully reliable estimate of the prevalence of food allergy/intolerance does not exist. Prevalence changes with age, as does the relative importance...... of the most common food allergens. The cumulative prevalence of allergy and intolerance to cow's milk during the first year of life is approximately 2%. The total prevalence of food allergy/intolerance in children is not as well documented. In 18-month-old infants the Danish estimate is 6.5%. The high...... prevalence of peanut allergy (0.5%) in British children is not reflected in the results from other European countries. Milk, egg, fish and oranges seem to be the most common causes of allergy and intolerance in European infants and children. Results from epidemiological studies combined with the knowledge...

  14. Understanding Food Allergies: How to Prevent Peanut Allergy and More

    Science.gov (United States)

    ... Subscribe March 2017 Print this issue Understanding Food Allergies How to Prevent Peanut Allergy and More En ... Allergy Therapy Seeking Allergy Relief Wise Choices Food Allergy Symptoms Pay attention to how you feel after ...

  15. Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy

    DEFF Research Database (Denmark)

    Fischer, L A; Menné, T; Avnstorp, C

    2009-01-01

    BACKGROUND: Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is a synthetic fragrance ingredient. Case reports of allergy to HICC appeared in the 1980s, and HICC has recently been included in the European baseline series. Human elicitation dose-response studies performed with different allergens...... to 21 days). Seventeen persons with no HICC allergy were included as control group for the ROAT. Results The response frequency to the ROAT (in microg HICC cm(-2) per application) was significantly higher than the response frequency to the patch test at one of the tested doses. Furthermore the response...

  16. Allergy immunotherapy across the life cycle to promote active and healthy ageing: From research to policies

    DEFF Research Database (Denmark)

    Calderon, M A; Demoly, P; Casale, T

    2016-01-01

    group of AIRWAYS integrated care pathways for airways diseases, the model of chronic respiratory diseases of the European Innovation Partnership on active and healthy ageing (DG CONNECT and DG Santé). It considered (1) the political background, (2) the rationale for allergen immunotherapy across...... the life cycle, (3) the unmet needs for the treatment, in particular in preschool children and old age adults, (4) the strategic framework and the practical approach to synergize current initiatives in allergen immunotherapy, its mechanisms and the concept of active and healthy ageing. © 2016 The Author(s).......Allergic diseases often occur early in life and persist throughout life. This life-course perspective should be considered in allergen immunotherapy. In particular it is essential to understand whether this al treatment may be used in old age adults. The current paper was developed by a working...

  17. CERIF: The Common European Research Information Format Model

    Directory of Open Access Journals (Sweden)

    Brigitte Jörg

    2010-09-01

    Full Text Available With increased computing power more data than ever are being and will be produced, stored and (re- used. Data are collected in databases, computed and annotated, or transformed by specific tools. The knowledge from data is documented in research publications, reports, presentations, or other types of files. The management of data and knowledge is difficult, and even more complicated is their re-use, exchange, or integration. To allow for quality analysis or integration across data sets and to ensure access to scientific knowledge, additional information - Research Information - has to be assigned to data and knowledge entities. We present the metadata model CERIF to add information to entities such as Publication, Project, Organisation, Person, Product, Patent, Service, Equipment, and Facility and to manage the semantically enhanced relationships between these entities in a formalized way. CERIF has been released as an EC Recommendation to European Member States in 2000. Here, we refer to the latest version CERIF 2008-1.0.

  18. Learning about Allergies

    Science.gov (United States)

    ... Videos for Educators Search English Español Learning About Allergies KidsHealth / For Kids / Learning About Allergies What's in ... in the spring. Why Do Some Kids Get Allergies? People may be born with a genetic (say: ...

  19. Tree Nut Allergies

    Science.gov (United States)

    ... Blog Vision Awards Common Allergens Tree Nut Allergy Tree Nut Allergy Learn about tree nut allergy, how ... a Tree Nut Label card . Allergic Reactions to Tree Nuts Tree nuts can cause a severe and ...

  20. Nut and Peanut Allergy

    Science.gov (United States)

    ... for Educators Search English Español Nut and Peanut Allergy KidsHealth / For Kids / Nut and Peanut Allergy What's ... getting worse. How Is a Nut or Peanut Allergy Diagnosed? If your doctor thinks you might have ...

  1. Pooling Birth Cohorts in Allergy and Asthma: European Union-Funded Initiatives - A MeDALL, CHICOS, ENRIECO, and GA(2)LEN Joint Paper

    Czech Academy of Sciences Publication Activity Database

    Bousquet, J.; Anto, J.; Sunyer, J.; Nieuwenhuijsen, N.; Vrijheid, M.; Keil, T.; Šrám, Radim

    2013-01-01

    Roč. 161, č. 1 (2013), s. 1-10 ISSN 1018-2438 Grant - others:EU FP6(XE) FOOD-CT-2004-506378 Institutional support: RVO:68378041 Keywords : Birth cohorts * asthma * allergy Subject RIV: DN - Health Impact of the Environment Quality Impact factor: 2.433, year: 2013

  2. Food Allergy and Attentional Coping in Adults

    OpenAIRE

    Gauchel, Jessica A.

    2017-01-01

    Food allergy affects approximately 9 million adults in the Unites States. The only medically approved treatment is avoidance of the allergenic food. Research has found food allergy to be associated with anxiety, depression, and lower quality of life, but has primarily focused on children. Little research has explored these associations in adults, and even less has examined the relationship between coping and food allergy in adults. Attentional coping is associated with ongoing symptom managem...

  3. SARNET: An European cooperative effort on LWR severe accident research

    International Nuclear Information System (INIS)

    Micaelli, Jean-Claude; Van Dorsselaere, Jean-Pierre; Chaumont, Bernard; Adroguer, Bernard; Haste, Tim; Bonnet, Jean-Michel; Meyer, Leonhard; Beraha, David; Trambauer, Klaus; Annunziato, Alessandro; Sehgal, Raj

    2006-01-01

    49 organisations network in SARNET (Severe Accident Research and management NETwork) their capacities of research in order to resolve the most important remaining uncertainties and safety issues for enhancing, in regard of Severe Accidents (SA), the safety of existing and future Nuclear Power Plants (NPPs). This project has been defined bearing in mind the necessity to optimise the use of the available means and to constitute sustainable research groups. SARNET tackles the fragmentation that exists between the different R and D national programmes, notably in defining common research programmes and developing common computer tools and methodologies for safety assessment. SARNET comprises most of the actors involved in SA research in Europe. To reach these objectives, all the organizations networked in SARNET contribute to a so-called Joint Programme of Activities (JPA), which can be broken in several elements: - Implementing an advanced communication tool for fostering exchange of information; - Harmonizing and re-orienting the research programmes, and defining commonly new ones; - Analysing commonly the experimental results provided by research programmes in order to elaborate a common understanding of concerned phenomena; - Developing ASTEC code (integral computer code used to predict the NPP behaviour during a postulated SA), which capitalizes in terms of physical models the knowledge produced within SARNET; - Developing Scientific Databases, in which all the results of research programmes are stored; - Developing a common methodology for Probabilistic Safety Assessment (PSA) of NNPs; - Developing educational courses and text (source) books; - Promoting personnel mobility between the various European organisations. A few organizations are covering a wide range of competences though not complete, whereas others are specialized in very specific areas and thus complementarities are developing. The critical mass of competence for performing experiments needed in the

  4. Main achievements of the european research project NERIS-TP

    International Nuclear Information System (INIS)

    Duranova, T.; Bohunova, J.; Raskop, W.; Schneider, T.; Liland, A.; Andronopoulos, S.; Mustonen, R.

    2014-01-01

    Activities of the NERIS-TP association are described. The NERIS ICRP Workshop, held in Bratislava, Slovak Republic in February 6-8, 2012, was organized by VUJE in cooperation with ICRP aiming to provide a forum for discussion and sharing of experiences on the implementation of the ICRP Recommendations. International, European and national perspectives were presented. 88 specialists from 51 organizations from 26 countries participated in the workshop. The final Dissemination Workshop 'Strengthening the Preparedness at National and Territorial Level Using New Tools and Methods - Stakeholders Experiences', was conducted in Oslo from 22 to 24 January 2014. International organisations such as HERCA, EC DG Research, IAEA, OECD/NEA, and NGOs such as NTW (Nuclear Transparency Watch) and GMF (Group of European Municipalities with Nuclear Facilities) as well as representatives of the OPERRA project participated in the workshop and particular panels. 82 experts and stakeholders participated in the workshop, representing twenty countries. Notably, participants from Japanese organisations provided first feedback from the management of the consequences of the Fukushima accident. (authors)

  5. All About Allergy Testing

    Science.gov (United States)

    American Academy of Allergy Asthma & Immunology Menu Search Main navigation Skip to content Conditions & Treatments Allergies Asthma Primary Immunodeficiency Disease Related Conditions Drug Guide Conditions Dictionary Just ...

  6. Fire Ant Allergy

    Science.gov (United States)

    American Academy of Allergy Asthma & Immunology Menu Search Main navigation Skip to content Conditions & Treatments Allergies Asthma Primary Immunodeficiency Disease Related Conditions Drug Guide Conditions Dictionary Just ...

  7. Allergy-Friendly Gardening

    Science.gov (United States)

    American Academy of Allergy Asthma & Immunology Menu Search Main navigation Skip to content Conditions & Treatments Allergies Asthma Primary Immunodeficiency Disease Related Conditions Drug Guide Conditions Dictionary Just ...

  8. Asthma, Allergies and Pregnancy

    Science.gov (United States)

    American Academy of Allergy Asthma & Immunology Menu Search Main navigation Skip to content Conditions & Treatments Allergies Asthma Primary Immunodeficiency Disease Related Conditions Drug Guide Conditions Dictionary Just ...

  9. The diagnosis and management of food allergies. Position paper of the Food Allergy Section the Polish Society of Allergology.

    Science.gov (United States)

    Bartuzi, Zbigniew; Kaczmarski, Maciej; Czerwionka-Szaflarska, Mieczysława; Małaczyńska, Teresa; Krogulska, Aneta

    2017-10-01

    The paper concerns the current position of the Polish Society of Allergology Food Allergy Section on the diagnosis and management of food allergies. The aim of this position is to provide evidence-based recommendations on the diagnosis and management of patients with allergic hypersensitivity to foods. This position statement includes a systematic review of studies in three areas, namely, the epidemiology, diagnosis and management of food allergies. While taking into account the specific Polish setting, in this publication we also used the current European Academy of Allergy and Clinical Immunology (EAACI) position paper and other current position statements, including those of the United States National Institute of Allergy and Infectious Diseases (NIAID).

  10. Review of European research trends of low dose radiation risk

    International Nuclear Information System (INIS)

    Iwasaki, Toshiyasu; Yoshida, Kazuo

    2010-01-01

    Large research projects on low dose radiation effects in Europe and US over the past decade have provided limited scientific knowledge which could underpin the validation of radiation protection systems. Recently in Europe, there have been repeated discussions and dialogues to improve the situation, and as the consequence, the circumstances surrounding low dose radiation risks are changing. In 2009, Multidisciplinary European Low Dose Initiative (MELODI) was established as a trans-national organization capable of ensuring appropriate governance of research in the pursuit of a long term shared vision, and Low Dose Research towards Multidisciplinary Integration (DoReMi) network was launched in 2010 to achieve fairly short term results in order to prove the validity of the MELODI approach. It is expected to be very effective and powerful activities to facilitate the reduction of uncertainties in the understanding of low dose risks, but the regulatory requests rushing the reinforcement of radiological protection regulations based on the precautional principles are more increasing. To develop reasonable radiological protection systems based on scientific evidences, we need to accelerate to collect scientific evidences which could directly underpin more appropriate radiation protection systems even in Japan. For the purpose, we Japan need to develop from an independent standpoint and share as a multidisciplinary vision a long term and holistic research strategy which enables to enhance Japanese advantages such as low dose rate facilities and animal facilities, as soon as possible. (author)

  11. THE PHENOMENON OF EUROPEAN MUSICAL ROMANTICISM IN SYSTEMIC RESEARCH VISION

    Directory of Open Access Journals (Sweden)

    FLOREA AUGUSTINA

    2015-09-01

    Full Text Available The Romanticism – European cultural-artistic phenomenon of the 20th century, developed in various fields of philosophy, literature, arts, and in terms of its amplitude and universality marked the respective century as a Romantic Era – is promoted in the most pointed manner in musical art. The Research of musical Romanticism – in the conceptual, aesthetic, musical aspect – can be achieved only on the basis of a systemic vision, which inputs the necessity of a study of synthesis. The respective study will integrate in a single process the investigation of all the above – mentioned aspects and will take place at the intersection of different scientific domains: aesthetics and musical aesthetics, historical and theoretical musicology, history and theory of interpretative art.

  12. Insect (food) allergy and allergens.

    Science.gov (United States)

    de Gier, Steffie; Verhoeckx, Kitty

    2018-05-03

    Insects represent an alternative for meat and fish in satisfying the increasing demand for sustainable sources of nutrition. Approximately two billion people globally consume insects. They are particularly popular in Asia, Latin America, and Africa. Most research on insect allergy has focussed on occupational or inhalation allergy. Research on insect food safety, including allergenicity, is therefore of great importance. The objective of this review is to provide an overview of cases reporting allergy following insect ingestion, studies on food allergy to insects, proteins involved in insect allergy including cross-reactive proteins, and the possibility to alter the allergenic potential of insects by food processing and digestion. Food allergy to insects has been described for silkworm, mealworm, caterpillars, Bruchus lentis, sago worm, locust, grasshopper, cicada, bee, Clanis bilineata, and the food additive carmine, which is derived from female Dactylopius coccus insects. For cockroaches, which are also edible insects, only studies on inhalation allergy have been described. Various insect allergens have been identified including tropomyosin and arginine kinase, which are both pan-allergens known for their cross-reactivity with homologous proteins in crustaceans and house dust mite. Cross-reactivity and/or co-sensitization of insect tropomyosin and arginine kinase has been demonstrated in house dust mite and seafood (e.g. prawn, shrimp) allergic patients. In addition, many other (allergenic) species (various non-edible insects, arachnids, mites, seafoods, mammals, nematoda, trematoda, plants, and fungi) have been identified with sequence alignment analysis to show potential cross-reactivity with allergens of edible insects. It was also shown that thermal processing and digestion did not eliminate insect protein allergenicity. Although purified natural allergens are scarce and yields are low, recombinant allergens from cockroach, silkworm, and Indian mealmoth are

  13. Combined Neutron Center for European Research and Technology

    International Nuclear Information System (INIS)

    Lagniel, Jean-Michel

    2002-01-01

    High-power proton linacs are needed as driver for several applications, namely transmutation of nuclear waste using Accelerator Driven Systems (ADS), spallation neutron sources (ESS in Europe) and other fields of basic and applied research (next generation of radioactive ion beam facilities, neutrino factories, muon colliders, irradiation facilities for material testing...). The possible synergies among these projects will be pointed out and the feasibility study of high-power proton linac used as driver of a multi-user facility (CONCERT) will be presented. There was excellent scientific, technical and economic reasons to study a Combined Neutron Center for European Research and Technology (CONCERT) based on a high-power proton accelerator. Such an installation would serve condensed matter studies by spallation neutron scattering, a technological irradiation tool and R and D facility for an hybrid reactor demonstrator, a radioactive ion beam facility for nuclear physics, R and D developments for a muon/neutrino facility. The installation could therefore constitute a European center of excellence in the field of neutronics where a large number of scientific and technical executives could be trained. The CONCERT Project Team has performed the feasibility study of such a multi-user facility with: - a review of the beam needs for the different applications, - an analyze of their compatibility, - the definition of the scope of a site-independent project, - a selection of the most appropriate options regarding scientific, technical, financial, organizational and administrative aspects, - an estimation of the costs for construction, operation and the needs in manpower. The conceptual design report [17] is sufficiently detailed to minimize contingencies on those parts of the project having a large potential impact in terms of performances, costs or delays. (author)

  14. Challenges in communicating research and research careers: lesson learned from the European Researchers' Nights at INGV

    Science.gov (United States)

    D'Addezio, Giuliana; Rubbia, Giuliana; Musacchio, Gemma; Lanza, Tiziana

    2014-05-01

    Since 2009 the Istituto Nazionale di Geofisica e Vulcanologia (INGV) participates to the European Researchers' Night, promoted by the European Commission, in the framework of Associazione Frascati Scienza (http://www.frascatiscienza.it/), with a program rich of events aimed at intriguingnand stimulating audiences of all ages about Earth Sciences, i.e., to make the general public aware on activities and roles of INGV researchers. For the September 27th Night, INGV contributed with a program in the INGV headquarters inspired by the INGV ScienzAperta Open Day held in April: guided tours, as well seminars held by researchers, exhibitions, educational games. We proposed two parallel programs: one devoted to earthquakes, including the visit to the INGV seismic surveillance room, seminars about Italian territory seismic hazard and exhibitions on Earthquakes and Volcanoes; the alternative program included the guided tour of the INGV laboratories (Aero-photogrammetry, Paleo-magnetism beside exhibition on geomagnetism, High Pressures and High Temperatures, Geochemistry, Restoration of historical instruments). In Frascati, we organized educational games, hands-on laboratories and a science theatre performance: "When the sky flashed red", as well as exhibitions at Museo Geofisico Rocca di Papa. A paper-based appreciation survey, compiled by visitors at INGV headquarter and by the scientific theatre's audiences, supplied our team with feedback, revealing some precious hints about users themselves, appreciation and margins of improvement, both in organization and in content. People of all ages and professions came. For example, a father asked specific paths for children, with even more appropriate language. A boy (aged 11) found the visit to the labs "interesting but a bit boring". It was suggested to prepare specific hand-outs for each visit, and certificates of participation for students. A girl, 9 years old, wrote that such event makes her closer to science world. The

  15. AURORA BOREALIS: a polar-dedicated European Research Platform

    Science.gov (United States)

    Wolff-Boenisch, Bonnie; Egerton, Paul; Thiede, Joern; Roberto, Azzolini; Lembke-Jene, Lester

    2010-05-01

    Polar research and in particular the properties of northern and southern high latitude oceans are currently a subject of intense scientific debate and investigations, because they are subject to rapid and dramatic climatic variations. Polar regions react more rapidly and intensively to global change than other regions of the earth. A shrinking of the Arctic sea-ice cover, potentially leading to an opening of sea passages to the north of North America and Eurasia, on the long to a "blue" Arctic Ocean would additionally have a strong impact on transport, commerce and tourism bearing potential risk for humans and complex ecosystems in the future. In spite of their critical role processes and feedbacks, especially in winter but not exclusively, are virtually unknown: The Arctic Ocean for example, it is the only basin of the world's oceans that has essentially not been sampled by the drill ships of the Deep-Sea Drilling Project (DSDP) or the Ocean Drilling Program (ODP) and its long-term environmental history and tectonic structure is therefore poorly known. Exceptions are the ODP Leg 151 and the more recent very successful ACEX-expedition of the Integrated Ocean Drilling Program (IODP) in 2004. To help to address the most pressing questions regarding climate change and related processes, a Pan-European initiative in the field of Earth system science has been put in place: AURORA BOREALIS is the largest environmental research infrastructure on the ESFRI roadmap of the European Community. AURORA BOREALIS is a very powerful research icebreaker, which will enable year-round operations in the Arctic and the Antarctic as well as in the adjacent ocean basins. Equipped with its drilling rig, the vessel is also capable to explore the presently completely unknown Arctic deep-sea floor. Last but not least, the ship is a floating observatory and mobile monitoring platform that permits to measure on a long-term basis comprehensive time series in all research fields relevant to

  16. Post-transplantation Development of Food Allergies.

    Science.gov (United States)

    Newman, Erik N; Firszt, Rafael

    2018-01-29

    The development of food allergies is increasingly being recognized as a post-solid organ transplant complication. In this article, we review the spectrum of post-transplant food allergy development and the proposed mechanisms for de novo food allergies and the clinical significance they pose. The development of new food allergies is disproportionately associated with pediatric liver transplants, where it occurs in up to 38% of select populations. The mechanism of food allergy development is not completely understood; however, it is likely promoted by unbalanced immune suppression. De novo food allergy development is a common complication of solid organ transplants with the highest risk occurring in pediatric liver transplant recipients. There are likely multiple mechanisms for food allergy development including passive transfer of membrane-bound IgE and lymphocytes from donor to recipient, as well as loss of food tolerance and active development of new food allergies. The optimal management of food allergies following organ transplants has not been well researched but may include changing the immune suppression regimen if the food allergy does not resolve without intervention.

  17. Food allergies.

    LENUS (Irish Health Repository)

    O'Leary, Paula F G

    2012-02-03

    Adverse reactions to foods are commonly implicated in the causation of ill health. However, foreign antigens, including food proteins and commensal microbes encountered in the gastrointestinal tract, are usually well tolerated. True food allergies, implying immune-mediated adverse responses to food antigens, do exist, however, and are especially common in infants and young children. Allergic reactions to food manifest clinically in a variety of presentations involving the gastrointestinal, cutaneous, and respiratory systems and in generalized reactions such as anaphylaxis. Both IgE-mediated and non-IgE-mediated immune mechanisms are recognized. Important advances in the clinical features underlying specific food hypersensitivity disorders are reviewed.

  18. Research projects in family medicine funded by the European Union.

    Science.gov (United States)

    Pavličević, Ivančica; Barać, Lana

    2014-01-01

    This study aimed at synthesizing funding opportunities in the field of family medicine by determining the number of family medicine projects, as well as number of project leaderships and/ or participations by each country. This was done in order to encourage inclusion of physicians in countries with underdeveloped research networks in successful research networks or to encourage them to form new ones. We searched the Community Research and Development Information Service project database in February 2013. Study covered the period from years 1992 - 2012, selecting the projects within the field of general/family medicine. The search was conducted in February 2013. First search conducted in the CORDIS database came up with a total of 466 projects. After excluding 241 projects with insufficient data, we analysed 225 remaining projects; out of those, 22 (9.8%) were in the field of family medicine and 203 (90.2%) were from other fields of medicine. Sorted by the number of projects per country, Dutch institutions had the highest involvement in family medicine projects and were partners or coordinators in 18 out of 22 selected projects (81.8%), followed by British institutions with 15 (68.8%), and Spanish with 10 projects (45.5%). Croatia was a partner in a single FP7 Health project. Research projects in family medicine funded by the European Union show significant differences between countries. Constant and high-quality international cooperation in family medicine is the prerequisite for improvement and development of scientific research and the profession. Copyright © 2014 by Academy of Sciences and Arts of Bosnia and Herzegovina.

  19. "Innovation and Intellectual Property Policies in European Research Infrastructure Consortia - PART I: The Case of the European Spallation Source ERIC"

    DEFF Research Database (Denmark)

    Yu, Helen; Wested, Jakob; Minssen, Timo

    2017-01-01

    of the problems society is facing today. To facilitate the creation and operation of such RIs, the EU adopted legal frameworks for European Research Infrastructure Consortia (ERIC). On August 31, 2015, the European Spallation Source (ESS) was established as an ERIC. Under the ERIC Regulations and ESS Statutes......, the European Spallation Source ERIC is required to adopt various policy documents relating to the operation and management of the facility. These cover a wide variety of issues such as user access, public procurement, intellectual property rights (IPR), data management, and dissemination. One of the main goals...

  20. "Innovation and Intellectual Property Policies in European Research Infrastructure Consortia - PART I: The Case of the European Spallation Source ERIC"

    DEFF Research Database (Denmark)

    Yu, Helen; Wested, Jakob; Minssen, Timo

    2017-01-01

    , the European Spallation Source ERIC is required to adopt various policy documents relating to the operation and management of the facility. These cover a wide variety of issues such as user access, public procurement, intellectual property rights (IPR), data management, and dissemination. One of the main goals...... of the problems society is facing today. To facilitate the creation and operation of such RIs, the EU adopted legal frameworks for European Research Infrastructure Consortia (ERIC). On August 31, 2015, the European Spallation Source (ESS) was established as an ERIC. Under the ERIC Regulations and ESS Statutes...... international research collaborations? The complex relationship between scientific excellence, innovation, and IPRs must be carefully considered. Taking the European Spallation Source ERIC as an example, this article investigates ERIC Regulations and EU policies and discusses what issues and perspectives ERICs...

  1. Allergen immunotherapy for insect venom allergy

    DEFF Research Database (Denmark)

    Dhami, S; Zaman, H; Varga, E-M

    2016-01-01

    BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines on Allergen Immunotherapy (AIT) for the management of insect venom allergy. To inform this process, we sought to assess the effectiveness, cost-effectiveness and safety...... of AIT in the management of insect venom allergy. METHODS: We undertook a systematic review, which involved searching 15 international biomedical databases for published and unpublished evidence. Studies were independently screened and critically appraised using established instruments. Data were...

  2. Understanding European education landscape on natural disasters - a textbook research

    Science.gov (United States)

    Komac, B.; Zorn, M.; Ciglič, R.; Steinführer, A.

    2012-04-01

    The importance of natural-disaster education for social preparedness is presented. Increasing damage caused by natural disasters around the globe draws attention to the fact that even developed societies must adapt to natural processes. Natural-disaster education is a component part of any education strategy for a sustainably oriented society. The purpose of this article is to present the role of formal education in natural disasters in Europe. To ensure a uniform overview, the study used secondary-school geography textbooks from the collection at the Georg Eckert Institute for International Textbook Research in Braunschweig, Germany. Altogether, nearly 190 textbooks from 35 European countries were examined. The greatest focus on natural disasters can be found in textbooks published in western Europe (3.8% of pages describing natural disasters), and the smallest in those published in eastern Europe (0.7%). A share of textbook pages exceeding three percent describing natural disasters can also be found in northern Europe (3.6%) and southeast Europe, including Turkey (3.4%). The shares in central and southern Europe exceed two percent (i.e., 2.8% and 2.3%, respectively). The types and specific examples of natural disasters most commonly covered in textbooks as well as the type of natural disasters presented in textbooks according to the number of casualties and the damage caused were analyzed. The results show that the majority of European (secondary-school) education systems are poorly developed in terms of natural-disaster education. If education is perceived as part of natural-disaster management and governance, greater attention should clearly be dedicated to this activity. In addition to formal education, informal education also raises a series of questions connected with the importance of this type of education. Special attention was drawn to the importance of knowledge that locals have about their region because this aspect of education is important in both

  3. Health economic analysis of allergen immunotherapy for the management of allergic rhinitis, asthma, food allergy and venom allergy: A systematic overview

    NARCIS (Netherlands)

    Asaria, M.; Dhami, S.; van Ree, R.; Gerth van Wijk, R.; Muraro, A.; Roberts, G.; Sheikh, A.

    2018-01-01

    Background: The European Academy of Allergy and Clinical Immunology (EAACI) is developing guidelines for allergen immunotherapy (AIT) for the management of allergic rhinitis, allergic asthma, IgE-mediated food allergy and venom allergy. To inform the development of clinical recommendations, we

  4. Is fruit and vegetable intake associated with asthma or chronic rhino-sinusitis in European adults? Results from the Global Allergy and Asthma Network of Excellence (GA2LEN) Survey

    DEFF Research Database (Denmark)

    Garcia-Larsen, Vanessa; Arthur, Rhonda; Potts, James F.

    2017-01-01

    was negatively associated with intake of dried fruits (β-coefficient -2.34; 95% confidence interval [CI] -4.09, -0.59), whilst CRS was statistically negatively associated with total intake of fruits (OR 0.73; 95% CI 0.55, 0.97). Conversely, a positive association was observed between asthma score and alliums......Background: Fruits and vegetables are rich in compounds with proposed antioxidant, anti-allergic and anti-inflammatory properties, which could contribute to reduce the prevalence of asthma and allergic diseases. Objective: We investigated the association between asthma, and chronic rhino......-sinusitis (CRS) with intake of fruits and vegetables in European adults. Methods: A stratified random sample was drawn from the Global Allergy and Asthma Network of Excellence (GA2LEN) screening survey, in which 55,000 adults aged 15-75 answered a questionnaire on respiratory symptoms. Asthma score (derived from...

  5. FOOD ALLERGY IN INFANTS

    Directory of Open Access Journals (Sweden)

    I.I. Balabolkin

    2006-01-01

    Full Text Available The article deals with the etiology, growth mechanisms, clinical implications, diagnostics and treatment of the infant food allergy. The author highlights the status of the allergy to the proteins of cow milk within this age group of children. Alongside the article describes the modern approaches to the diet therapy of the infants with the allergy to the proteins of cow milk.Key words: infant, food allergy, allergy to the proteins of cow milk, diet therapy.

  6. Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries

    LENUS (Irish Health Repository)

    Whitfield, Kate

    2010-11-12

    Abstract Background \\'Compassionate use\\' programmes allow medicinal products that are not authorised, but are in the development process, to be made available to patients with a severe disease who have no other satisfactory treatment available to them. We sought to understand how such programmes are regulated in ten European Union countries. Methods The European Clinical Research Infrastructures Network (ECRIN) conducted a comprehensive survey on clinical research regulatory requirements, including questions on regulations of \\'compassionate use\\' programmes. Ten European countries, covering approximately 70% of the EU population, were included in the survey (Austria, Denmark, France, Germany, Hungary, Ireland, Italy, Spain, Sweden, and the UK). Results European Regulation 726\\/2004\\/EC is clear on the intentions of \\'compassionate use\\' programmes and aimed to harmonise them in the European Union. The survey reveals that different countries have adopted different requirements and that \\'compassionate use\\' is not interpreted in the same way across Europe. Four of the ten countries surveyed have no formal regulatory system for the programmes. We discuss the need for \\'compassionate use\\' programmes and their regulation where protection of patients is paramount. Conclusions \\'Compassionate use\\' is a misleading term and should be replaced with \\'expanded access\\'. There is a need for expanded access programmes in order to serve the interests of seriously ill patients who have no other treatment options. To protect these patients, European legislation needs to be more explicit and informative with regard to the regulatory requirements, restrictions, and responsibilities in expanded access programmes.

  7. Compassionate use of interventions: results of a European Clinical Research Infrastructures Network (ECRIN) survey of ten European countries

    Science.gov (United States)

    2010-01-01

    Background 'Compassionate use' programmes allow medicinal products that are not authorised, but are in the development process, to be made available to patients with a severe disease who have no other satisfactory treatment available to them. We sought to understand how such programmes are regulated in ten European Union countries. Methods The European Clinical Research Infrastructures Network (ECRIN) conducted a comprehensive survey on clinical research regulatory requirements, including questions on regulations of 'compassionate use' programmes. Ten European countries, covering approximately 70% of the EU population, were included in the survey (Austria, Denmark, France, Germany, Hungary, Ireland, Italy, Spain, Sweden, and the UK). Results European Regulation 726/2004/EC is clear on the intentions of 'compassionate use' programmes and aimed to harmonise them in the European Union. The survey reveals that different countries have adopted different requirements and that 'compassionate use' is not interpreted in the same way across Europe. Four of the ten countries surveyed have no formal regulatory system for the programmes. We discuss the need for 'compassionate use' programmes and their regulation where protection of patients is paramount. Conclusions 'Compassionate use' is a misleading term and should be replaced with 'expanded access'. There is a need for expanded access programmes in order to serve the interests of seriously ill patients who have no other treatment options. To protect these patients, European legislation needs to be more explicit and informative with regard to the regulatory requirements, restrictions, and responsibilities in expanded access programmes. PMID:21073691

  8. European research and development on HTGR process heat applications

    International Nuclear Information System (INIS)

    Verfondern, Karl; Lensa, Werner von

    2003-01-01

    The High-Temperature Gas-Cooled Reactor represents a suitable and safe concept of a future nuclear power plant with the potential to produce process heat to be utilized in many industrial processes such as reforming of natural gas, coal gasification and liquefaction, heavy oil recovery to serve for the production of the storable commodities hydrogen or energy alcohols as future transportation fuels. The paper will include a description of the broad range of applications for HTGR process heat and describe the results of the German long-term projects ''Prototype Nuclear Process Heat Reactor Project'' (PNP), in which the technical feasibility of an HTGR in combination with a chemical facility for coal gasification processes has been proven, and ''Nuclear Long-Distance Energy Transportation'' (NFE), which was the demonstration and verification of the closed-cycle, long-distance energy transmission system EVA/ADAM. Furthermore, new European research initiatives are shortly described. A particular concern is the safety of a combined nuclear/chemical facility requiring a concept against potential fire and explosion hazards. (author)

  9. A European multi-language initiative to make the general population aware of independent clinical research: the European Communication on Research Awareness Need project

    OpenAIRE

    Mosconi, Paola; Antes, Gerd; Barbareschi, Giorgio; Burls, Amanda; Demotes-Mainard, Jacques; Chalmers, Iain; Colombo, Cinzia; Garattini, Silvio; Gluud, Christian; Gyte, Gill; Mcllwain, Catherine; Penfold, Matt; Post, Nils; Satolli, Roberto; Valetto, Maria Rosa

    2016-01-01

    BACKGROUND: The ECRAN (European Communication on Research Awareness Needs) project was initiated in 2012, with support from the European Commission, to improve public knowledge about the importance of independent, multinational, clinical trials in Europe. \\ud \\ud METHODS: Participants in the ECRAN consortium included clinicians and methodologists directly involved in clinical trials; researchers working in partnership with the public and patients; representatives of patients; and experts in s...

  10. Allergy prevention.

    Science.gov (United States)

    Muche-Borowski, Cathleen; Kopp, Matthias; Reese, Imke; Sitter, Helmut; Werfel, Thomas; Schäfer, Torsten

    2010-09-01

    The further increase of allergies in industrialized countries demands evidence-based measures of primary prevention. The recommendations as published in the guideline of 2004 were updated and consented on the basis of a systematic literature search. Evidence from the period February 2003-May 2008 was searched in the electronic databases Cochrane and MEDLINE as well as in reference lists of recent reviews and by contacting experts. The retrieved citations were screened for relevance first by title and abstract and in a second step as full paper. Levels of evidence were assigned to each included study and the methodological quality of the studies was assessed as high or low. Finally the revised recommendations were formally consented (nominal group process) by representatives of relevant societies and organizations including a self-help group. Of originally 4556 hits, 217 studies (4 Cochrane Reviews, 14 meta-analyses, 19 randomized controlled trials, 135 cohort and 45 case-control studies) were included and critically appraised. Grossly unchanged remained the recommendations on avoiding environmental tobacco smoke, breast-feeding over 4 months (alternatively hypoallergenic formulas for children at risk), avoiding a mold-promoting indoor climate, vaccination according to current recommendations, and avoidance of furry pets (especially cats) in children at risk. The recommendation on reducing the house dust mite allergen exposure as a measure of primary prevention was omitted and the impact of a delayed introduction of supplementary food was reduced. New recommendations were adopted concerning fish consumption (during pregnancy / breast-feeding and as supplementary food in the first year), avoidance of overweight, and reducing the exposure to indoor and outdoor air pollutants. The revision of this guideline on a profound evidence basis led to (1) a confirmation of existing recommendations, (2) substantial revisions, and (3) new recommendations. Thereby it is possible

  11. Research on nuclear energy within the European Commission Research Framework Programme

    International Nuclear Information System (INIS)

    Forsstroem, H.

    2000-01-01

    The strategic goal of the 5 th EURATOM RTD Framework Programme (FP5) is to help exploit the full potential of nuclear energy in a sustainable manner, by making current technologies even safer and more economical and by exploring promising new concepts. The programme covers nuclear fusion, nuclear fission and radiation protection. Part of the programme on nuclear fission and radiation protection is being implemented through ''indirect actions'', i.e. research co-sponsored (up to 50% of total costs) and co-ordinated by DG RESEARCH of the European Commission (EC) but carried out by external public and private organisations as multi-partner projects. The budget available for these indirect actions during FP5 (1998-2002) is 191 MEuro. The programme covers four different areas: safety of existing reactors, including plant life management, severe accident management and development of evolutionary systems; safety of the fuel cycle, including radioactive waste management and disposal, partitioning and transmutation and decommissioning of nuclear installation; safety of future systems, including new or revisited reactor or fuel cycle concepts; radiation protection and radiological sciences, including both basic radiobiology and radiophysics and issues connected to the application of radiation protection. After the first calls for proposals of FP5, which were evaluated in 1999 about 140 research projects have been selected for funding and is now in the process of starting. In parallel the research projects that were supported in the 4th Framework Programme (1994 - 1998) are coming to an end, and being reported, at the same time as the first thoughts on the 6 t h FP are discussed.An important new component for the future research in Europe is the concept of a European Research Area (ERA). The purpose of ERA is to create better overall framework conditions for research in Europe. Some of the concepts being discussed in this context are networking of centres of excellence, a

  12. The perspective of European researchers of national occupational safety and health institutes for contributing to a European research agenda: a modified Delphi study.

    Science.gov (United States)

    Gagliardi, Diana; Rondinone, Bruna M; Mirabile, Marco; Buresti, Giuliana; Ellwood, Peter; Hery, Michel; Paszkiewicz, Peter; Valenti, Antonio; Iavicoli, Sergio

    2017-06-23

    This study, developed within the frame of the Partnership for European Research on Occupational Safety and Health joint research activities and based on the frame designed by the 2013 European Agency for Safety and Health at Work (EU-OSHA) study, is the first example of using the points of view of European occupational safety and health (OSH) researchers.The objective is to identify priorities for OSH research that may contribute to the achievement of present and future sustainable growth objectives set by the European strategies. The study was carried out using a modified Delphi method with a two-round survey. Each round involved a panel of about 110 researchers representing the network member institutes was selected according to specific criteria, including the ownership of research expertise in at least one of the four macroareas identified by the reference report developed by EU-OSHA in 2013. The study identified some innovative research topics (for example, 'Emerging technological devices' and 'OSH consequences of markets integration') and research priorities (ie, crowdsourcing, e-work, zero-hours contract s ) that are not reflected in previous studies of this nature.The absence of any reference to violence and harassment at work among the researchers' proposals is a major difference from previous similar studies, while topics related to gender issues and electromagnetic fields show a lower importance. The innovative design of a research priorities identification process, which takes advantage of a large, representative and qualified panel of European researchers allowed the definition of a number of research priorities able to support the inclusion of innovative OSH research issues in the scope of the next European research agenda. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Manifesto for a European Anxiety Disorders Research Network

    NARCIS (Netherlands)

    Baldwin, David S.; Allgulander, Christer; Altamura, Alfredo Carlo; Angst, Jules; Bandelow, Borwin; den Boer, Johan; Boyer, Patrice; Davies, Simon; dell'Osso, Bernardo; Eriksson, Elias; Fineberg, Naomi; Fredrikson, Mats; Herran, Andres; Maron, Eduard; Metspalu, Andres; Nutt, David; van der Wee, Nic; Luis Vazquez-Barquero, Jose; Zohar, Joseph

    Despite the size, burden and costs of anxiety disorders, many patients remain unrecognised, and the effectiveness of evidence-based interventions in routine clinical practice can be disappointing. The European College of Neuropsychopharmacology (ECNP) has established the ECNP Network Initiative

  14. EUFOREA Rhinology Research Forum 2016: report of the brainstorming sessions on needs and priorities in rhinitis and rhinosinusitis

    NARCIS (Netherlands)

    Hellings, P. W.; Akdis, C. A.; Bachert, C.; Bousquet, J.; Pugin, B.; Adriaensen, G.; Advani, R.; Agache, I.; Anjo, C.; Anmolsingh, R.; Annoni, E.; Bieber, T.; Bizaki, A.; Braverman, I.; Callebaut, I.; Castillo Vizuete, J. A.; Chalermwatanachai, T.; Chmielewski, R.; Cingi, C.; Cools, L.; Coppije, C.; Cornet, M. E.; de Boeck, I.; de Corso, E.; de Greve, G.; Doulaptsi, M.; Edmiston, R.; Erskine, S.; Gevaert, E.; Gevaert, P.; Golebski, K.; Hopkins, C.; Hox, V.; Jaeggi, C.; Joos, G.; Khwaja, S.; Kjeldsen, A.; Klimek, L.; Koennecke, M.; Kortekaas Krohn, I.; Krysko, O.; Kumar, B. N.; Langdon, C.; Lange, B.; Lekakis, G.; Levie, P.; Lourijsen, E.; Lund, V. J.; Martens, K.; Mő Sges, R.; Mullol, J.; Nyembue, T. D.; Palkonen, S.; Philpott, C.; Pimentel, J.; Poirrier, A.; Pratas, A. C.; Prokopakis, E.; Pujols, L.; Rombaux, P.; Schmidt-Weber, C.; Segboer, C.; Spacova, I.; Staikuniene, J.; Steelant, B.; Steinsvik, E. A.; Teufelberger, A.; van Gerven, L.; van Gool, K.; Verbrugge, R.; Verhaeghe, B.; Virkkula, P.; Vlaminck, S.; Vries-Uss, E.; Wagenmann, M.; Zuberbier, T.; Seys, S. F.; Fokkens, W. J.

    2017-01-01

    The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS) and the

  15. The perspective of European researchers of national occupational safety and health institutes for contributing to a European research agenda: a modified Delphi study

    Science.gov (United States)

    Gagliardi, Diana; Rondinone, Bruna M; Mirabile, Marco; Buresti, Giuliana; Ellwood, Peter; Hery, Michel; Paszkiewicz, Peter; Valenti, Antonio; Iavicoli, Sergio

    2017-01-01

    Objectives This study, developed within the frame of the Partnership for European Research on Occupational Safety and Health joint research activities and based on the frame designed by the 2013 European Agency for Safety and Health at Work (EU-OSHA) study, is the first example of using the points of view of European occupational safety and health (OSH) researchers. The objective is to identify priorities for OSH research that may contribute to the achievement of present and future sustainable growth objectives set by the European strategies. Methods The study was carried out using a modified Delphi method with a two-round survey. Each round involved a panel of about 110 researchers representing the network member institutes was selected according to specific criteria, including the ownership of research expertise in at least one of the four macroareas identified by the reference report developed by EU-OSHA in 2013. Results The study identified some innovative research topics (for example, ‘Emerging technological devices’ and ‘OSH consequences of markets integration’) and research priorities (ie, crowdsourcing, e-work, zero-hours contracts) that are not reflected in previous studies of this nature. The absence of any reference to violence and harassment at work among the researchers’ proposals is a major difference from previous similar studies, while topics related to gender issues and electromagnetic fields show a lower importance. Conclusions The innovative design of a research priorities identification process, which takes advantage of a large, representative and qualified panel of European researchers allowed the definition of a number of research priorities able to support the inclusion of innovative OSH research issues in the scope of the next European research agenda. PMID:28645965

  16. Educational Research Capacity Building in the European Union: A Critique of the Lived Experiences of Emerging Researchers

    Science.gov (United States)

    Hallet, Fiona; Fidalgo, Patricia

    2014-01-01

    The purpose of this article is to explore the extent to which European Union (EU) policies impact upon the activities of associations such as the European Educational Research Association (EERA) and the experiences of emerging researchers aligned to such associations. In essence, the authors explore potential tensions between policy and the lived…

  17. Research and Grant Management: The Role of the Project Management Office (PMO) in a European Research Consortium Context

    Science.gov (United States)

    Wedekind, Gerben Kristian; Philbin, Simon Patrick

    2018-01-01

    This paper illustrates how a university-based project management office (PMO) can provide focused support across the entire grant project lifecycle within a European research context. In recent years, EU (European Union) research and innovation grant programs have increasingly shifted to support multidisciplinary consortia composed of industry,…

  18. The Past and the Future of Holocaust Research : From Disparate Sources to an Integrated European Holocaust Research Infrastructure

    NARCIS (Netherlands)

    Blanke, Tobias; Daelen, Veerle Vanden; Frankl, Michal; Kristel, Conny; Rodriguez, Kepa; Speck, Reto; Rapp, Andrea; Lossau, Norbert; Neurot, Heike

    2014-01-01

    The European Holocaust Research Infrastructure (EHRI) has been set up by the European Union to create a sustainable complex of services for researchers. EHRI will bring together information about dispersed collections, based on currently more than 20 partner organisations in 13 countries and many

  19. The changing geoepidemiology of food allergies.

    Science.gov (United States)

    Leung, Patrick S C; Shu, Shang-An; Chang, Christopher

    2014-06-01

    The science of food allergy has been rapidly evolving before our eyes in the past half century. Like other allergic disorders, the prevalence of food allergies has dramatically increased, and coupled with the increased public awareness of anaphylaxis due to food allergy, this has driven an explosion in basic and clinical research in this extremely broad subject. Treatment of food allergies has evolved and practices such as food challenges have become an integral part of an allergy practice. The impact of the increase of food allergy has driven package labeling laws, legislation on emergency treatment availability in schools and other public places, and school policy. But to this day, our knowledge of the pathogenesis of food allergy is still incomplete. There are the most obvious IgE-mediated immediate hypersensitivity reactions, but then multiple previously unidentified conditions such as eosinophilic esophagitis, food protein-induced enterocolitis syndrome, milk protein allergy, food-induced atopic dermatitis, oral allergy syndrome, and others have complicated the diagnosis and management of many of our patients who are unable to tolerate certain foods. Many of these conditions are not IgE-mediated, but may be T cell-driven diseases. The role of T regulatory cells and immune tolerance and the newly discovered immunological role of vitamin D have shed light on the variable clinical presentation of food allergy and the development of new methods of immunotherapy in an example of bench-to-bedside research. Component-resolved diagnostic techniques have already begun to allow us to more precisely define the epitopes that are targeted in food allergic patients. The development of biological modulators, research on genomics and proteomics, and epigenetic techniques all offer promising avenues for new modes of therapy of food allergy in the twenty-first century.

  20. Egyptian Journal of Pediatric Allergy and Immunology (The ...

    African Journals Online (AJOL)

    Focus and Scope. This journal is the official journal of the Egyptian Society of Pediatric Allergy and Immunology. It is he first Egyptian Journal specialized in the field of allergy and immunology in the pediatric age group. It is a forum for the presentation and promotion of new researches in the field of allergy and immunology, ...

  1. Egyptian Journal of Pediatric Allergy and Immunology (The)

    African Journals Online (AJOL)

    This journal is the official journal of the Egyptian Society of Pediatric Allergy and Immunology. It is he first Egyptian Journal specialized in the field of allergy and immunology in the pediatric age group. It is a forum for the presentation and promotion of new researches in the field of allergy and immunology, for maintaining ...

  2. European research project 'Metrology for radioactive waste management'

    International Nuclear Information System (INIS)

    Suran, J.

    2014-01-01

    The three-year European research project M etrology for Radioactive Waste Management' was launched in October 2011 under the EMRP (European Metrology Research Programme). It involves 13 European national metrology institutes and a total budget exceeds four million Euros. The project is coordinated by the Czech Metrology Institute and is divided into five working groups. This poster presents impact, excellence, relevance to EMPR objectives, and implementation and management of this project.(author)

  3. Water reactor fuel research at the Joint Research Centre of the Commission of the European Union

    Energy Technology Data Exchange (ETDEWEB)

    Markgraf, J [HFR Unit, Inst. for Advanced Materials, Petten (Netherlands)

    1997-12-01

    The JRC programmes 1995-1998 are in progress within 8 JRC Institutes located within different research centres situated in five member states of the European Union. Except for the area of reactor safety and waste management, there are no JRC research programmes related to water reactor fuel directly. However, the JRC is providing support on basis of contracts and cooperations to bilateral and international R and D programmes through access to its large test facilities like the High Flux Reactor at the JRC Petten and the hot cell facilities of the Transuranium Institute at the JRC Karlsruhe. Access is available to customers from all over the world. 3 tabs.

  4. Allergen immunotherapy for IgE-mediated food allergy

    DEFF Research Database (Denmark)

    Dhami, Sangeeta; Nurmatov, Ulugbek; Pajno, Giovanni Battista

    2016-01-01

    BACKGROUND: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for IgE-mediated food allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in IgE-mediated food...

  5. Infant feeding and allergy prevention: a review of current knowledge and recommendations. A EuroPrevall state of the art paper

    DEFF Research Database (Denmark)

    Grimshaw, K.E.C.; Allen, K.; Edwards, C.A.

    2009-01-01

    of firm evidence the recommendations differ widely. This review has been developed as part of EuroPrevall, a European multicentre research project funded by the European Union, to document the differing feeding recommendations made across Europe, to investigate the current evidence base for any allergy......The relationship between infant feeding patterns and the later development of food allergies has been the focus of much debate and research over the last decade. National recommendations have been made by many countries on how to feed infants to reduce the risk of food allergy but due to the lack...... prevention feeding recommendations and to identify areas where further research is needed. This review will also provide information which, when combined with the infant feeding data collected as part of EuroPrevall, will give an indication of compliance to national feeding guidelines which can be utilised...

  6. Infant feeding and allergy prevention: a review of current knowledge and recommendations. A EuroPrevall state of the art paper.

    LENUS (Irish Health Repository)

    Grimshaw, K E C

    2009-10-01

    The relationship between infant feeding patterns and the later development of food allergies has been the focus of much debate and research over the last decade. National recommendations have been made by many countries on how to feed infants to reduce the risk of food allergy but due to the lack of firm evidence the recommendations differ widely. This review has been developed as part of EuroPrevall, a European multicentre research project funded by the European Union, to document the differing feeding recommendations made across Europe, to investigate the current evidence base for any allergy prevention feeding recommendations and to identify areas where further research is needed. This review will also provide information which, when combined with the infant feeding data collected as part of EuroPrevall, will give an indication of compliance to national feeding guidelines which can be utilised to assess the effectiveness of current dissemination and implementation strategies.

  7. Inhalant allergies in children.

    Science.gov (United States)

    Mims, James W; Veling, Maria C

    2011-06-01

    Children with chronic or recurrent upper respiratory inflammatory disease (rhinitis) should be considered for inhalant allergies. Risk factors for inhalant allergies in children include a first-degree relative with allergies, food allergy in infancy, and atopic dermatitis. Although inhalant allergies are rare in infancy, inhalant allergies are common in older children and impair quality of life and productivity. Differentiating between viral and allergic rhinitis can be challenging in children, but the child's age, history, and risk factors can provide helpful information. Allergic rhinitis is a risk factor for asthma, and if one is present, medical consideration of the other is warranted. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Developmental trajectories in food allergy: a review.

    LENUS (Irish Health Repository)

    DunnGalvin, A

    2009-01-01

    Increasing recognition of the importance of the relationships between perceptions, emotions, behaviors and health has changed the way health and disease are portrayed and researched. A chronic condition may affect and\\/or interact with already existing normative demands and changes in socialization. Although the prevalence of food allergy and anaphylaxis have been reportedly increasing, the emotional and social impact of growing up with food allergy has received little emphasis. In this paper, we present current findings on the biopsychosocial impact of food allergy on children in order to gain insight into the food allergy experience, from the perspective of the child, teen, and parent living with food allergy, with particular attention to developmental aspects. Due to the scarcity of publications on the psychosocial dimensions of food allergy, we also draw on selected literature on children\\'s and parent\\'s experience of, and coping with chronic disease that may inform research into food allergy. To this end, we review some general developmental mechanisms that may underpin and explain normative age-graded shifts in patterns of coping across childhood and adolescence. We also highlight gaps in the literature and assess implications of current research in food allergy and other chronic diseases for intervention and prevention of negative short and long term outcomes.

  9. An assessment of long term ecosystem research activities across European socio-ecological gradients

    NARCIS (Netherlands)

    Metzger, M.J.; Bunce, R.G.H.; Eupen, van M.; Mirtl, M.

    2010-01-01

    Integration of European long term ecosystem research (LTER) would provide important support for the management of the pan-European environment and ecosystems, as well as international policy commitments. This does require appropriate coverage of Europe and standardised frameworks and research

  10. The European standard series. European Environmental and Contact Dermatitis Research Group (EECDRG)

    DEFF Research Database (Denmark)

    Bruynzeel, D P; Andersen, Klaus Ejner; Camarasa, J G

    1995-01-01

    Changes to the European standard series which have taken place since the last officially recommended alterations in 1988, are explained. New to the series is the sesquiterpene lactone mix. The PPD black rubber mix and the quinoline mix have been replaced by single components; one of the p-hydroxy...

  11. The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC: experiences from a successful ERS Clinical Research Collaboration

    Directory of Open Access Journals (Sweden)

    James D. Chalmers

    2017-09-01

    To understand the role of Clinical Research Collaborations as the major way in which the European Respiratory Society can stimulate clinical research in different disease areas To understand some of the key features of successful disease registries To review key epidemiological, clinical and translational studies of bronchiectasis contributed by the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC project in the past 5 years To understand the key research priorities identified by EMBARC for the next 5 years

  12. Towards a food allergy free world

    NARCIS (Netherlands)

    Houben, G.

    2016-01-01

    The international food industry appreciates the benefits of sharing its research load via collaborative programs with partners. TNO offers you the opportunity to participate in its strategic Shared Research Program (SRP) ‘Towards a Food Allergy Free World’.

  13. Pediatric allergy and immunology in Spain.

    Science.gov (United States)

    Nieto, Antonio; Mazon, Angel; Martin-Mateos, Maria Anunciacion; Plaza, Ana-Maria; Garde, Jesus; Alonso, Elena; Martorell, Antonio; Boquete, Manuel; Lorente, Felix; Ibero, Marcel; Bone, Javier; Pamies, Rafael; Garcia, Juan Miguel; Echeverria, Luis; Nevot, Santiago; Martinez-Cañavate, Ana; Fernandez-Benitez, Margarita; Garcia-Marcos, Luis

    2011-11-01

    The data of the ISAAC project in Spain show a prevalence of childhood asthma ranging from 7.1% to 15.3%, with regional differences; a higher prevalence, 22.6% to 35.8%, is described for rhinitis, and atopic dermatitis is found in 4.1% to 7.6% of children. The prevalence of food allergy is 3%. All children in Spain have the right to be visited in the National Health System. The medical care at the primary level is provided by pediatricians, who have obtained their titles through a 4-yr medical residency training program. The education on pediatric allergy during that period is not compulsory and thus very variable. There are currently 112 certified European pediatric allergists in Spain, who have obtained the accreditation of the European Union of Medical Specialist for proven skills and experience in pediatric allergy. Future specialists in pediatric allergy should obtain their titles through a specific education program to be developed in one of the four accredited training units on pediatric allergy, after obtaining the title on pediatrics. The Spanish Society of Pediatric Allergy and Clinical Immunology (SEICAP) gathers over 350 pediatric allergists and pediatricians working in this field. SEICAP has a growing activity including yearly congresses, continued education courses, elaboration of technical clinical documents and protocols, education of patients, and collaboration with other scientific societies and associations of patients. The official journal of SEICAP is Allergologia et Immunophatologia, published every 2 months since 1972. The web site of SEICAP, http://www.seicap.es, open since 2004, offers information for professionals and extensive information on pediatric allergic and immunologic disorders for the lay public; the web site is receiving 750 daily visits during 2011. The pediatric allergy units are very active in clinical work, procedures as immunotherapy or induction of oral tolerance in food allergy, contribution to scientific literature, and

  14. Sorting Out Seasonal Allergies

    Science.gov (United States)

    ... Close ‹ Back to Healthy Living Sorting Out Seasonal Allergies Sneezing, runny nose, nasal congestion. Symptoms of the ... How do I know if I have seasonal allergies? According to Dr. Georgeson, the best way to ...

  15. Multidisciplinary Approaches to Allergies

    NARCIS (Netherlands)

    Gao Zhongshan,; Shen, Hua-Hao; Zheng, M.; Frewer, L.J.; Gilissen, L.J.W.J.

    2012-01-01

    Allergy is an immunological disease caused by multiple factors and characterized by variability, specificity and complexity. "Multidisciplinary Approaches to Allergies" covers diverse aspects ranging from basic molecular mechanisms to societal issues within the framework of multidisciplinary

  16. Antihistamines for allergies

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000549.htm Antihistamines for allergies To use the sharing features on this page, please enable JavaScript. Antihistamines are drugs that treat allergy symptoms . When taken by mouth, they come as ...

  17. Asthma and Food Allergies

    Science.gov (United States)

    ... Español Text Size Email Print Share Asthma and Food Allergies Page Content Article Body A family history of ... child may develop asthma . Children with asthma and food allergies are at increased risk for anaphylaxis, a severe ...

  18. Do Allergies Cause Asthma?

    Science.gov (United States)

    ... is to avoid being around those allergens. The doctor also may prescribe medicine for your allergies if you can't completely avoid ... Allergy-Triggered Asthma Your House: How to Make It Asthma-Safe Air Pollution & ...

  19. Do Allergies Cause Asthma?

    Science.gov (United States)

    ... Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family Life First Aid & Safety Doctors & ... Can I Deal With My Asthma? Allergy Testing Definition: Allergy-Triggered Asthma Asthma Center Asthma View more ...

  20. Allergies, asthma, and dust

    Science.gov (United States)

    Reactive airway disease - dust; Bronchial asthma - dust; Triggers - dust ... Things that make allergies or asthma worse are called triggers. Dust is a common trigger. When your asthma or allergies become worse due to dust, you are ...

  1. Allergies, asthma, and molds

    Science.gov (United States)

    Reactive airway - mold; Bronchial asthma - mold; Triggers - mold; Allergic rhinitis - pollen ... Things that make allergies or asthma worse are called triggers. Mold is a common trigger. When your asthma or allergies become worse due to mold, you are ...

  2. European network infrastructures of observatories for terrestrial Global Change research

    Science.gov (United States)

    Vereecken, H.; Bogena, H.; Lehning, M.

    2009-04-01

    The earth's climate is significantly changing (e.g. IPCC, 2007) and thus directly affecting the terrestrial systems. The number and intensity hydrological extremes, such as floods and droughts, are continually increasing, resulting in major economical and social impacts. Furthermore, the land cover in Europe has been modified fundamentally by conversions for agriculture, forest and for other purposes such as industrialisation and urbanisation. Additionally, water resources are more than ever used for human development, especially as a key resource for agricultural and industrial activities. As a special case, the mountains of the world are of significant importance in terms of water resources supply, biodiversity, economy, agriculture, traffic and recreation but particularly vulnerable to environmental change. The Alps are unique because of the pronounced small scale variability they contain, the high population density they support and their central position in Europe. The Alps build a single coherent physical and natural environment, artificially cut by national borders. The scientific community and governmental bodies have responded to these environmental changes by performing dedicated experiments and by establishing environmental research networks to monitor, analyse and predict the impact of Global Change on different terrestrial systems of the Earths' environment. Several European network infrastructures for terrestrial Global Change research are presently immerging or upgrading, such as ICOS, ANAEE, LifeWatch or LTER-Europe. However, the strongest existing networks are still operating on a regional or national level and the historical growth of such networks resulted in a very heterogeneous landscape of observation networks. We propose therefore the establishment of two complementary networks: The NetwOrk of Hydrological observAtories, NOHA. NOHA aims to promote the sustainable management of water resources in Europe, to support the prediction of

  3. GASTROINTESTINAL FOOD ALLERGY IN CHILDREN

    Directory of Open Access Journals (Sweden)

    Svetlana G. Makarova

    2017-01-01

    Full Text Available In recent years, there has been a significant increase in the prevalence  of food allergies. Pathological conditions associated  with a food intolerance are becoming an increasingly urgent problem of pediatrics. According to different researchers, allergic lesions of the gastrointestinal tract occurs in 25–50% of patients with such common pathology as an allergy to cow's milk proteins. The severity of diseases  associated  with food allergies and their prognosis  depend largely on early diagnosis and adequate treatment. Difficulties and errors  in the diagnosis  of gastrointestinal  food allergies  are associated  with both subjective  and objective  reasons,  primarily due to the fact that gastrointestinal  reactions to food are often delayed and non-IgE-mediated. The article describes clinical forms of gastrointestinal food allergy according to the existing classification. Diagnostic algorithms and modern approaches  to differential diagnosis of disease based on evidence-based  medicine and corresponding to international consensus papers are given.

  4. Building the European Research Area in nuclear fission pioneering steps in actinide science

    International Nuclear Information System (INIS)

    Forsstroem, Hans

    2004-01-01

    The concept of the European Research Area (ERA) aims at closer development of research policies in Europe and closer networking of research capacities, to reduce fragmentation of research in Europe. The goal is to make European research more effective and competitive. Several approaches are made to create ERA. The European Research Framework Programme is one tool in this context, with the introduction of the new instruments, Integrated Projects, Networks of Excellence and Integrated Infrastructure Initiatives. Actinide science is one area that could benefit from better coordination and more effective use of the research capacities, both human and physical. The European Commission is thus funding a Network of Excellence (ACTINET-6) and an Integrated Project (EUROPART) in this area within the sixth EURATOM Framework Programme. (author)

  5. [The role of the microbial environment for the development of childhood asthma and allergies].

    Science.gov (United States)

    Braun-Fahrländer, Charlotte

    2013-12-01

    Asthma and allergies are among the most frequent chronic diseases in childhood. Their prevalence has increased during the second half of the twentieth century but seem to stabilize in recent years in many Western European countries such as Switzerland. Although the genetic background is known to have a strong impact on an individual's risk to develop asthma or allergy it seems likely that environmental factors are mostly responsible for the increase in prevalence over time. Much research has been devoted to environmental risk factors promoting the development of asthma and allergies. Yet, there is increasing interest in environmental factors which might protect from the development of these diseases and which might have been reduced along with the development of a "Western lifestyle". The role of environmental allergens, the hygiene hypothesis and the role of the farm environment on the development of asthma and allergies are discussed. An emphasis is put on the microbial environment as encountered in the farming environment which has been shown to confer protection from the development of asthma and allergies. It is likely that among other factors the development of a "Western lifestyle" went along with a marked change of the microbial environment children are exposed to.

  6. European research on Climat change impact on human health and environment

    OpenAIRE

    Pogonysheva I. A.; Kuznetsova V. P.; Pogonyshev D. A.; Lunyak I. I.

    2018-01-01

    European countries have accumulated a considerable body of research that proves both direct and indirect influence of climate change on human health. The article analyses “Protecting health in an environment challenged by climate change: European Regional Framework for Action”. The article gives a detailed analysis of the work of European Office of World Health Organisation and The United Nations Economic Commission for Europe related to climate change.

  7. Strategy for sustainability of the Joint European Research Infrastructure Network for Coastal Observatories - JERICO

    OpenAIRE

    Puillat, Ingrid; Farcy, Patrick; Durand, Dominique; Petihakis, George; Morin, Pascal; Kriegger, Magali; Petersen, Wilhelm; Tintoré, Joaquin; Sorensen, Kai; Sparnocchia, Stefania; Wehde, Henning

    2015-01-01

    The JERICO European research infrastructure (RI) is integrating several platform types i.e. fixed buoys, piles, moorings, drifters, Ferryboxes, gliders, HF radars, coastal cable observatories and the associated technologies dedicated to the observation and monitoring of the European coastal seas. The infrastructure is to serve both the implementation of European marine policies and the elucidation of key scientific questions through dedicated observation and monitoring plans. It includes obse...

  8. Seasonal Allergies (Hay Fever)

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Seasonal Allergies (Hay Fever) KidsHealth / For Parents / Seasonal Allergies (Hay ... español Alergia estacional (fiebre del heno) About Seasonal Allergies "Achoo!" It's your son's third sneezing fit of ...

  9. Addressing Food Allergies

    Science.gov (United States)

    DeVoe, Jeanne Jackson

    2008-01-01

    Since 1960, the incidence of food allergies in children has grown fivefold, from 1 in 100 children to 1 in 20 children, according to the Food Allergy Initiative. Food allergies cause anaphylactic shock, the most severe type of allergic reaction, which can lead to death within minutes if left untreated. While there are no standard guidelines from…

  10. Kids with Food Allergies

    Science.gov (United States)

    ... To Recipe Substitutions Substitutions for Milk Substitutions for Egg Substitutions for Wheat and Gluten Substitutions for Soy Substitutions for Peanuts and Tree Nuts Substitutions for Corn Menu Planning for the Food Allergy Cook Food & Cooking Support Forum Allergy-Friendly Foods Allergy ...

  11. Coconut Allergy Revisited

    OpenAIRE

    Anagnostou, Katherine

    2017-01-01

    Despite concerns voiced often by food-allergic patients, allergy to coconut is rare, not directly associated with nut allergy and few cases are reported so far in the literature. We present an interesting case of coconut allergy in a child that was previously tolerant to coconut and regularly exposed via both the skin and gastrointestinal route.

  12. FOOD ALLERGY IN CHILDHOOD

    Directory of Open Access Journals (Sweden)

    Marta Santalha

    2017-01-01

    Conclusions: In these cases, most children had co-sensitization with other allergens, as well as another manifestation of concomitant allergy, showing the role of food allergy in allergic march. Food allergy diagnosis is extremely important, as it can be potentially serious if not prevented by food avoidance.

  13. Milk Allergy in Infants

    Science.gov (United States)

    ... Safe Videos for Educators Search English Español Milk Allergy in Infants KidsHealth / For Parents / Milk Allergy in ... Alergia a la leche en bebés About Milk Allergy People of any age can have a milk ...

  14. FOOD ALLERGY PREVENTION IN INFANCY

    Directory of Open Access Journals (Sweden)

    S.G. Makarova

    2006-01-01

    Full Text Available The article deals with new data about food tolerance induction among the children, belonging to the high risk groups disposed to atopy. Authors show the role of gut microflora in formation of child immune system, effect of breast feeding on activation of local immune response, growth stimulation of bifid bacteria and lactic acid bacilli. The present work gives the randomized research findings, which confirm the effectiveness of prolonged breast feeding, use of highly or partially hydrolyzed mixtures and timely introduction of supplemental feeding in food allergy prevention.Key words: prevention, food allergy, children, breast feeding, hypo allergic mixtures, milk protein hydrolysates, supplemental feeding, gut microflora, probiotics.

  15. Contact allergy to rubber accelerators remains prevalent

    DEFF Research Database (Denmark)

    Schwensen, J F; Menné, T; Johansen, J D

    2016-01-01

    several clinical cases with allergic facial dermatitis to rubber. OBJECTIVES: To evaluate temporal trends of contact allergy to rubber accelerators from the European baseline series in a tertiary patch test clinic in Denmark, and examine associations with anatomical locations of dermatitis. METHODS: Patch...... test and clinical data collected in a Danish tertiary dermatology clinic in Gentofte, Herlev, Copenhagen between 1 January 2005 and 31 December 2014 were analysed. The following rubber accelerators or mixtures in petrolatum from the European baseline patch test series were included: thiuram mix 1.......0%, mercaptobenzothiazole 2.0% and mercapto mix 1.0%. RESULTS: The overall prevalence of contact allergy to rubber accelerators was 3.1% with no significant change during the study period (Ptrend = 0.667). Contact allergy to thiuram mix was the most prevalent and was significantly associated with occupational contact...

  16. Allergic sensitization to ovalbumin in mouse model of food allergy is accompanied by stimulation of enterocyte brush border alkaline phosphatase activity

    Czech Academy of Sciences Publication Activity Database

    Schwarzer, Martin; Kozáková, Hana; Goliáš, Jaroslav; Kverka, Miloslav; Cinová, Jana; Rossmann, Pavel; Tučková, Ludmila

    2012-01-01

    Roč. 6, č. 1 (2012), s. 53-53 ISSN 1555-8932. [Meeting of the European Intestinal Transport Group /24./. 04.09.2012-07.09.2012, Oxford] R&D Projects: GA AV ČR IAA500200913 Institutional research plan: CEZ:AV0Z50200510 Keywords : ovalbumin * allergy Subject RIV: EC - Immunology

  17. Temporal trends of preservative allergy in Denmark (1985-2008).

    Science.gov (United States)

    Thyssen, Jacob P; Engkilde, Kåre; Lundov, Michael D; Carlsen, Berit C; Menné, Torkil; Johansen, Jeanne D

    2010-02-01

    Most cosmetics and industrial products contain preservatives. Preservative allergy is common and, historically, changing contact allergy epidemics caused by preservatives have been observed. In 1997, Alan Dillarstone predicted a stable development of preservative allergy following mandatory ingredient labelling on cosmetic products. To investigate the development in the prevalence of preservative allergy in Denmark over a 24-year period (1985-2008) and to challenge the prediction made by Dillarstone. A retrospective analysis of patch test data was performed (n = 18179). Comparisons were made using a chi(2) test. Logistic regression analyses were used to test for associations. The development of preservative allergy mirrored those of other European patch test centres. The development was not dependent on sex or age group. The prevalence was higher among women and those aged 41-60 years. Formaldehyde allergy was persistently prevalent over the study years. The overall prevalence of preservative allergy increased significantly (P(trend) = 0.001), mainly because of patch testing with additional preservatives in recent years. Dillarstone's prediction was confirmed as the prevalence of contact allergy to individual preservatives remained relatively stable. However, the overall burden of preservative allergy seemed to increase. Introduction of new preservatives may add to the burden of contact allergy.

  18. European Research and Development in Hybrid Flexible Electronics

    Science.gov (United States)

    2010-07-01

    meetings in late 2008. WTEC then recruited a panel of U.S. experts, chaired by Ananth Dodabalapur, the Ashley H. Priddy Centennial Professor in...Engineering, The University of Texas at Austin Ananth Dodabalapur is the Ashley H. Priddy Centennial Professor in Engineering at the University of Texas...output from the East Asian countries has inevitably depressed the world share of U.S. and European papers (except for Spain); India, however, has

  19. An assessment of long term ecosystem research activities across European socio-ecological gradients.

    Science.gov (United States)

    Metzger, M J; Bunce, R G H; van Eupen, M; Mirtl, M

    2010-06-01

    Integration of European long term ecosystem research (LTER) would provide important support for the management of the pan-European environment and ecosystems, as well as international policy commitments. This does require appropriate coverage of Europe and standardised frameworks and research methods between countries. Emerging interest in socio-ecological systems prompted the present assessment of the distribution of LTER activities across European socio-ecological gradients. This paper presents a European stratification with a 1 km(2) resolution, delineating 48 broad socio-ecological regions. The dataset is based on an existing biogeophysical stratification constructed using multivariate clustering of mainly climatic variables and a newly developed socio-economic stratification based on an economic density indicator. The coverage of European LTER facilities across the socio-ecological gradients is tested using this dataset. The analysis shows two strong biases in the present LTER effort. Firstly, urban and disturbed regions are consistently under-represented, illustrating a bias for traditional ecological research away from human activity. Secondly, the Mediterranean, for which some of the most extreme global change impacts are projected, is receiving comparatively little attention. Both findings can help guide future investment in the European LTER network - and especially in a Long Term Socio-Ecological Research (LTSER) component- to provide a more balanced coverage. This will provide better scientific understanding of pan-European environmental concerns and support the management of natural resources and international policy commitments in the European Union. (c) 2010 Elsevier Ltd. All rights reserved.

  20. MUPBED: A Pan-European Prototype for Multi-Domain Research Networks

    DEFF Research Database (Denmark)

    Spaeth, Jan; Cavazzoni, Carlo; Foisel, Hans-Martin

    2009-01-01

    Integration and full interoperability are challenging areas of research in wide-area networks today. A European project, MUPBED, has recently concluded and achieved the main result of integrating and demonstrating technologies and network solutions that enable the operation of future European res...

  1. The European Repository Landscape 2008 : Inventory of Digital Repositories for Research Output

    NARCIS (Netherlands)

    Van der Graaf, Maurits

    2009-01-01

    It is widely acknowledged that a common knowledge base for European research is necessary. The DRIVER project aims towards this. European practices may be harmonised and the development of stateof-the-art technology facilitated. As a first step, a clear picture of the state-of-the-art of the

  2. Charities' response to the European Commission call of interest for their involvement in the European Research Area

    CERN Document Server

    Sessano, D.

    2003-01-01

    This paper presents an exploratory study to investigate what could be the role of the charities concerned with scientific research in the European Research Area (ERA). The analysis particularly concentrates on UK and Italy. The questions on which the exploratory study was developed are: 1. “In what specific areas of the ERA did the European Commission (EC) for the involvement of charities? And could there be other areas in which charities might participate?” 2. “Given the role and situation of charities in UK and Italy, what role, if any, could they be willing to play in the ERA? Is it the same as the one proposed by the Commission or not?” In order to answer these questions, the following discussion will focus at first on a short overview of the charity sector, both at the general level and at the national level in UK and Italy. Then a brief presentation of the European Research Area will be given. The hypotheses of the study will then be presented, followed by a methodological section. Results wi...

  3. The European initiative on low-dose risk research: from the HLEG to MELODI

    International Nuclear Information System (INIS)

    Belli, Mauro; Tabocchini, Maria Antonella; Jourdain, Jean-Rene; Repussard, Jacques; Salomaa, Sisko

    2015-01-01

    The importance of low-dose risk research for radiation protection is now widely recognised. The European Commission (EC) and five European Union (EU) Member States involved in the Euratom Programme set up in 2008 a 'High Level and Expert Group on European Low Dose Risk Research' (HLEG) aimed at identifying research needs and proposing a better integration of European efforts in the field. The HLEG revised the research challenges and proposed a European research strategy based on a 'Multidisciplinary European Low Dose Initiative' (MELODI). In April 2009, five national organisations, with the support of the EC, created the initial core of MELODI (http://www.melodi-online.eu) with a view to integrate the EU institutions with significant programmes in the field, while being open to other scientific organisations and stakeholders, and to develop an agreed strategic research agenda (SRA) and roadmap. Since then, open workshops have been organised yearly, exploring ideas for SRA implementation. As of October 2014, 31 institutions have been included as members of MELODI. HLEG recommendations and MELODI SRA have become important reference points in the radiation protection part of the Euratom Research Programme. MELODI has established close interactions through Memorandum of Understanding with other European platforms involved in radiation protection (Alliance, NERIS and EURADOS) and, together with EURADOS, with the relevant medical European Associations. The role of Joint Programming in priority setting, foreseen in the forthcoming EU Horizon 2020, calls for keeping MELODI an open, inclusive and transparent initiative, able to avoid redundancies and possible conflicts of interest, while promoting common initiatives in radiation protection research. An important issue is the establishment of a proper methodology for managing these initiatives, and this includes the set-up of an independent MELODI Scientific Committee recently extended to Alliance, NERIS

  4. The European initiative on low-dose risk research: from the HLEG to MELODI.

    Science.gov (United States)

    Belli, Mauro; Tabocchini, Maria Antonella; Jourdain, Jean-René; Salomaa, Sisko; Repussard, Jacques

    2015-09-01

    The importance of low-dose risk research for radiation protection is now widely recognised. The European Commission (EC) and five European Union (EU) Member States involved in the Euratom Programme set up in 2008 a 'High Level and Expert Group on European Low Dose Risk Research' (HLEG) aimed at identifying research needs and proposing a better integration of European efforts in the field. The HLEG revised the research challenges and proposed a European research strategy based on a 'Multidisciplinary European LOw Dose Initiative' (MELODI). In April 2009, five national organisations, with the support of the EC, created the initial core of MELODI (http://www.melodi-online.eu) with a view to integrate the EU institutions with significant programmes in the field, while being open to other scientific organisations and stakeholders, and to develop an agreed strategic research agenda (SRA) and roadmap. Since then, open workshops have been organised yearly, exploring ideas for SRA implementation. As of October 2014, 31 institutions have been included as members of MELODI. HLEG recommendations and MELODI SRA have become important reference points in the radiation protection part of the Euratom Research Programme. MELODI has established close interactions through Memorandum of Understanding with other European platforms involved in radiation protection (Alliance, NERIS and EURADOS) and, together with EURADOS, with the relevant medical European Associations. The role of Joint Programming in priority setting, foreseen in the forthcoming EU Horizon 2020, calls for keeping MELODI an open, inclusive and transparent initiative, able to avoid redundancies and possible conflicts of interest, while promoting common initiatives in radiation protection research. An important issue is the establishment of a proper methodology for managing these initiatives, and this includes the set-up of an independent MELODI Scientific Committee recently extended to Alliance, NERIS and EURADOS, with

  5. Stress and food allergy: mechanistic considerations.

    Science.gov (United States)

    Schreier, Hannah M C; Wright, Rosalind J

    2014-04-01

    Recent years have seen a marked increase in food allergy prevalence among children, particularly in Western countries, that cannot be explained by genetic factors alone. This has resulted in an increased effort to identify environmental risk factors underlying food allergies and to understand how these factors may be modified through interventions. Food allergy is an immune-mediated adverse reaction to food. Consequently, considerations of candidate risk factors have begun to focus on environmental influences that perturb the healthy development of the emerging immune system during critical periods of development (eg, prenatally and during early childhood), particularly in the gut. Given that psychosocial stress is known to play an important role in other allergic and inflammatory diseases, such as asthma, its potential role in food allergy is a growing area of research. However, research to date has largely focused on animal studies. This review synthesizes relevant animal research and epidemiological data, providing proof of concept for moderating influences of psychological stress on food allergy outcomes in humans. Pathways that may underlie associations between psychosocial stress and the expression of food allergy are discussed. Copyright © 2014 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  6. The European Research Infrastructures of the ESFRI Roadmap in Biological and Medical Sciences: status and perspectives

    Directory of Open Access Journals (Sweden)

    Alessia Calzolari

    2014-06-01

    Full Text Available INTRODUCTION. Since 2002, the European Strategy Forum on Research Infrastructures identified the needs for Research Infrastructures (RIs in Europe in priority fields of scientific research and drafted a strategic document, the ESFRI Roadmap, defining the specific RIs essential to foster European research and economy. The Biological and Medical Sciences RIs (BMS RIs were developed thanks to the active participation of many institutions in different European member states associated to address the emerging needs in biomedicine and, among these, the Italian National Institute of Health (ISS, in virtue of its role in public health and research, has been specifically involved in the national development and implementation of three RIs: the Biobanking and Biomolecular Resources Research Infrastructure (BBMRI, the European Advanced Translational Research Infrastructure in Medicine (EATRIS and the European Clinical Research Infrastructures Network (ECRIN. AIM. This article outlines the design and development of these RIs up to the recent achievement of the ERIC status, their importance in the Horizon 2020 programme and their societal and economic potential impact, with special attention to their development and significance in Italy. CONCLUSIONS. The ISS plays a unique role in fostering a coordinated participation of excellence Italian institutes/facilities to different European biomedical RIs, thus contributing to health innovation, healthcare optimization, and healthcare cost containment.

  7. EUFOREA Rhinology Research Forum 2016

    DEFF Research Database (Denmark)

    Hellings, P W; Akdis, C A; Bachert, C

    2017-01-01

    The first European Rhinology Research Forum organized by the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) was held in the Royal Academy of Medicine in Brussels on 17th and 18th November 2016, in collaboration with the European Rhinologic Society (ERS......) and the Global Allergy and Asthma European Network (GA2LEN). One hundred and thirty participants (medical doctors from different specialties, researchers, as well as patients and industry representatives) from 27 countries took part in the multiple perspective discussions including brainstorming sessions on care...... pathways and research needs in rhinitis and rhinosinusitis. The debates started with an overview of the current state of the art, including weaknesses and strengths of the current practices, followed by the identification of essential research needs, thoroughly integrated in the context of Precision...

  8. Recommendation to increase the test concentration of methylchloroisothiazolinone/methylisothiazolinone in the European baseline patch test series - on behalf of the European Society of Contact Dermatitis and the European Environmental and Contact Dermatitis Research Group.

    Science.gov (United States)

    Bruze, Magnus; Goossens, An; Isaksson, Marléne

    2014-07-01

    Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) in aqua is present in the European baseline patch test series at 100 ppm, whereas 200 ppm has been used in Sweden since 1986, in Spain in the late 1980s, and, in recent years, also in the United Kingdom and Ireland. With regard to MCI/MI, to investigate the data on contact allergy rates in dermatitis patients, the frequencies of allergic contact dermatitis in the same group, and adverse reactions, particularly patch test sensitization in tested dermatitis patients, and to find the optimal patch test concentration as dose in mg/cm(2) . We performed a survey of the literature found via the National Library of Medicine (PubMed, http://www.ncbi.nlm.nih.gov/pubmed, last accessed 20 February 2014). MCI/MI at 200 ppm aq. diagnosis substantially more contact allergy and allergic contact dermatitis, without any registered increase in patch test sensitization, than the presently used concentration of 100 ppm. MCI/MI at 200 ppm aq. is recommended to be included in the European baseline patch test series. To avoid patch test sensitization, a dose of 0.006 mg/cm(2) must not be exceeded, which means a volume of 15 µl for Finn Chambers(®) (Ø 8 mm). © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. REVIEW OF THE EUROPEAN SYSTEMS RESEARCH PROGRAMS OF URBAN TERRITORIES

    Directory of Open Access Journals (Sweden)

    L. N. Kovalskyi

    2017-01-01

    Full Text Available The model of sustainable development of the territory should be in a state of control and management. The system of urban monitoring of Ukraine does not fully provide information on the level of sustainable development of settlements and regions. Therefore, it is necessary to create systems for monitoring indicators of sustainable development of human settlements and regions. The objective of this study is to analyze the existing programs for stimulating sustainable development in European countries and to develop recommendations on the need to organize such systems in Ukraine and to improve the system of urban monitoring. The article describes such systems and programs: URBACT is a program for sharing best practices between cities by creating thematic networks. URBACT’s mission is to encourage cities to work together and develop integrated solutions to common urban problems, through networking, to learn from each other’s experiences and identify best practices in order to improve urban policies; URBAN AUDIT – a large set of statistical information. The main objective of the system is to provide objective and comparable statistical data on European cities; URBAN ATLAS – provides a pan-European comparison of urban land use data. The information is in the form of open geospatial data. The system is aimed at facilitating work on site planning and site accounting. It is necessary to adopt the best practices of implementing sustainable development technology and apply it in other countries that have chosen a model for their development – a model for sustainable development of the territory. The current system of town-planning monitoring in Ukraine needs to be improved and given a new task – to take into account indicators of sustainable development of the territories. This system is most suitable for this task, since urban monitoring already takes into account certain indicators in the form of spatial data.

  10. 40 years of biannual family medicine research meetings--the European General Practice Research Network (EGPRN).

    Science.gov (United States)

    Buono, Nicola; Thulesius, Hans; Petrazzuoli, Ferdinando; Van Merode, Tiny; Koskela, Tuomas; Le Reste, Jean-Yves; Prick, Hanny; Soler, Jean Karl

    2013-12-01

    To document family medicine research in the 25 EGPRN member countries in 2010. Semi-structured survey with open-ended questions. Academic family medicine in 23 European countries, Israel, and Turkey. 25 EGPRN national representatives. Demographics of the general population and family medicine. Assessments, opinions, and suggestions. EGPRN has represented family medicine for almost half a billion people and > 300,000 general practitioners (GPs). Turkey had the largest number of family medicine departments and highest density of GPs, 2.1/1000 people, Belgium had 1.7, Austria 1.6, and France 1.5. Lowest GP density was reported from Israel 0.17, Greece 0.18, and Slovenia 0.4 GPs per 1000 people. Family medicine research networks were reported by 22 of 25 and undergraduate family medicine research education in 20 of the 25 member countries, and in 10 countries students were required to do research projects. Postgraduate family medicine research was reported by 18 of the member countries. Open-ended responses showed that EGPRN meetings promoted stimulating and interesting research questions such as comparative studies of chronic pain management, sleep disorders, elderly care, healthy lifestyle promotion, mental health, clinical competence, and appropriateness of specialist referrals. Many respondents reported a lack of interest in family medicine research related to poor incentives and low family medicine status in general and among medical students in particular. It was suggested that EGPRN exert political lobbying for family medicine research. Since 1974, EGPRN organizes biannual conferences that unite and promote primary care practice, clinical research and academic family medicine in 25 member countries.

  11. The impact of European research ethics legislation on UK radiology research activity: a bibliometric analysis

    International Nuclear Information System (INIS)

    Johnson, C.A.; Toms, A.P.

    2009-01-01

    Aim: To determine whether there is evidence of a reduction in radiology research activity in the UK following the implementation of the European research ethics legislation, which came in to force in 2001 and has been widely criticised as an impediment to research. Materials and methods: A bibliometric analysis was performed by searching PubMed for all first-author publications from UK departments of 'radiology' or 'medical imaging' between 1995 and 2007. Results were subcategorized into those papers published in the highest cited general radiology journals and by publication type: original research, reviews, and case reports. Results: From 1995 to 2007 the total number of publications rose by 6.5% from 137 to 146 with the increase occurring in non-general radiology journals. Original articles fell from 18 in 1995 to 12 in 2003, but then rose to 24 by 2007 (33% rise). This dip was paralleled by a fall and then recovery in case report publications. The most dramatic change has been in the number of review articles, which has increased more than eightfold from seven in 1995 to 65 in 2007 to become the most common form of publication. Conclusion: The overall number of original scientific articles, published by first-author UK radiologists, has increased slightly over the last 12 years despite a temporary fall associated with the introduction of new research ethics legislation.

  12. European Educational Research Quality Indicators (EERQI): A first prototype framework of intrinsic and extrinsic indicators

    NARCIS (Netherlands)

    Mooij, Ton

    2011-01-01

    Mooij, T. (2011, 15-16 March). European Educational Research Quality Indicators (EERQI): A first prototype framework of intrinsic and extrinsic indicators. Paper presented at the final EERQI conference, Brussels, University Foundation.

  13. The 19th Annual Congress of European Public Relations Education and Research Association (EUPRERA 2017)

    NARCIS (Netherlands)

    Kviatek, Beata

    2017-01-01

    The European Public Relations Education and Research Association (EUPRERA) is an independent organization that aims at stimulating and promoting innovative knowledge and practices of strategic communication, organizational communication and Public Relations across Europe. Founded in 1959 and

  14. Pediatric allergy and immunology in Turkey.

    Science.gov (United States)

    Celik, Gülfem; Bakirtas, Arzu; Sackesen, Cansin; Reisli, Ismail; Tuncer, Ayfer

    2011-06-01

    Allergic diseases constitute a significant health problem in Turkey. According to a recent multicenter study, which used the ISAAC questionnaire, the mean prevalence of wheezing, rhinoconjunctivitis, and eczema in 10-yr-old school children during the past year was 15.8%, 23.5%, and 8.1%, respectively. A healthcare level system, regulated by Ministry of Health, is available in Turkey. Pediatric allergists and pediatric immunologists provide patient care at the tertiary level. Currently, 48 centers deliver care for allergic and immunologic diseases in children. There are 136 pediatric and 61 adult allergists/immunologists. Although the number of allergy/clinical immunology specialists is limited, these centers are capable of delivering many of the procedures required for the proper management and diagnosis of allergy/immunology. Pediatric allergy and/or immunology is a subspecialty lasting 3 yr and follows a 4-yr pediatric specialist training. Fellow training involves gaining knowledge in basic and clinical allergy and immunology as well as the performance and interpretation of laboratory procedures in the field of allergy and clinical immunology. The Turkish National Society of Allergy and Clinical Immunology (TNSACI) was officially established in 1989 and currently has 356 members. The society organizes a national congress annually and winter schools for fellowship training as well as training courses for patients and their relatives. TNSACI also has a strong representation in European Academy of Allergy and Clinical Immunology (EAACI) and European Society for Immunodeficiencies (ESID) through its participation in the executive committee, consensus reports, and initiatives in the diagnosis of allergic and immunologic diseases of children. The 30th Congress of the EAACI is also due to be held in Istanbul, Turkey, between June 11 and 15, 2011. © 2011 John Wiley & Sons A/S.

  15. EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy.

    Science.gov (United States)

    Muraro, A; Werfel, T; Hoffmann-Sommergruber, K; Roberts, G; Beyer, K; Bindslev-Jensen, C; Cardona, V; Dubois, A; duToit, G; Eigenmann, P; Fernandez Rivas, M; Halken, S; Hickstein, L; Høst, A; Knol, E; Lack, G; Marchisotto, M J; Niggemann, B; Nwaru, B I; Papadopoulos, N G; Poulsen, L K; Santos, A F; Skypala, I; Schoepfer, A; Van Ree, R; Venter, C; Worm, M; Vlieg-Boerstra, B; Panesar, S; de Silva, D; Soares-Weiser, K; Sheikh, A; Ballmer-Weber, B K; Nilsson, C; de Jong, N W; Akdis, C A

    2014-08-01

    Food allergy can result in considerable morbidity, impact negatively on quality of life, and prove costly in terms of medical care. These guidelines have been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group, building on previous EAACI position papers on adverse reaction to foods and three recent systematic reviews on the epidemiology, diagnosis, and management of food allergy, and provide evidence-based recommendations for the diagnosis and management of food allergy. While the primary audience is allergists, this document is relevant for all other healthcare professionals, including primary care physicians, and pediatric and adult specialists, dieticians, pharmacists and paramedics. Our current understanding of the manifestations of food allergy, the role of diagnostic tests, and the effective management of patients of all ages with food allergy is presented. The acute management of non-life-threatening reactions is covered in these guidelines, but for guidance on the emergency management of anaphylaxis, readers are referred to the related EAACI Anaphylaxis Guidelines. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. Patients with multiple contact allergies

    DEFF Research Database (Denmark)

    Carlsen, Berit Christina; Andersen, Klaus Ejner; Menné, Torkil

    2008-01-01

    Patients with multiple contact allergies, also referred to as polysensitized, are more frequent than predicted from prevalence of single sensitivities. The understanding of why some people develop multiple contact allergies, and characterization of patients with multiple contact allergies...... of developing multiple contact allergies. Evidence of allergen clusters among polysensitized individuals is also reviewed. The literature supports the idea that patients with multiple contact allergies constitute a special entity within the field of contact allergy. There is no generally accepted definition...... of patients with multiple contact allergies. We suggest that contact allergy to 3 or more allergens are defined as multiple contact allergies....

  17. Studies in cow’s milk allergy: results from the Dutch EuroPrevall birth cohort

    NARCIS (Netherlands)

    Petrus, N.C.M.

    2016-01-01

    Cow’s milk allergy is a common disease in infancy. However, until recently accurate numbers were not available. To investigate how many infants suffered from cow’s milk allergy, the EuroPrevall study was designed. In this European, multicentre study, nine European hospitals followed over 12,000

  18. Licensing review process of the European Spallation Source (ESS) research facility

    International Nuclear Information System (INIS)

    Brewitz, Erica

    2014-01-01

    On 3 January 2012 a license application under the Radiation Protection Act (SFS, 1988b) for the European Spallation Source research facility was submitted to the Swedish Radiation Safety Authority. The European Spallation Source research facility will be the site of a new and quite unusual kind of neutron source, based on a large proton accelerator that bombards a heavy material with protons. The Swedish Radiation Safety Authority is now reviewing the application. (authors)

  19. European Wind Atlas and Wind Resource Research in Denmark

    DEFF Research Database (Denmark)

    Mortensen, Niels Gylling

    to estimate the actual wind climate at any specific site and height within this region. The Danish and European Wind Atlases are examples of how the wind atlas methodology can be employed to estimate the wind resource potential for a country or a sub-continent. Recently, the methodology has also been used...... - from wind measurements at prospective sites to wind tunnel simulations and advanced flow modelling. Among these approaches, the wind atlas methodology - developed at Ris0 National Laboratory over the last 25 years - has gained widespread recognition and is presently considered by many as the industry......-standard tool for wind resource assessment and siting of wind turbines. The PC-implementation of the methodology, the Wind Atlas Analysis and Application Program (WAsP), has been applied in more than 70 countries and territories world-wide. The wind atlas methodology is based on physical descriptions and models...

  20. Drug allergy passport and other documentation for patients with drug hypersensitivity

    DEFF Research Database (Denmark)

    Brockow, Knut; Aberer, Werner; Atanaskovic-Markovic, M

    2016-01-01

    The strongest and best-documented risk factor for drug hypersensitivity (DH) is the history of a previous reaction. Accidental exposures to drugs may lead to severe or even fatal reactions in sensitized patients. Preventable prescription errors are common. They are often due to inadequate medical...... history or poor risk assessment of recurrence of drug reaction. Proper documentation is essential information for the doctor to make sound therapeutic decision. The European Network on Drug Allergy and Drug Allergy Interest Group of the European Academy of Allergy and Clinical Immunology have formed...... a task force and developed a drug allergy passport as well as general guidelines of drug allergy documentation. A drug allergy passport, a drug allergy alert card, a certificate, and a discharge letter after medical evaluation are adequate means to document DH in a patient. They are to be handed...

  1. European Food Safety Authority; Response to comments on the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the scientific substantiation of a health claim related to beta-palmitate and increased calcium absorption pursuant to Article 14 of Regulation (EC

    DEFF Research Database (Denmark)

    Tetens, Inge

    Following a request from the European Commission, EFSA was asked to review the scientific comments received on the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the scientific substantiation of a health claim related to beta-palmitate and increased...... calcium absorption pursuant to Article 14 of Regulation (EC) No 1924/2006. Comments submitted to EFSA via the European Commission Services originated from the applicant (IDACE). EFSA has reviewed the comments and shared them with the chair of the NDA Panel, Prof. Albert Flynn, and the chair of the NDA...

  2. European health research and globalisation: is the public-private balance right?

    Directory of Open Access Journals (Sweden)

    McCarthy Mark

    2011-03-01

    Full Text Available Abstract Background The creation and exchange of knowledge between cultures has benefited world development for many years. The European Union now puts research and innovation at the front of its economic strategy. In the health field, biomedical research, which benefits the pharmaceutical and biotechnology industries, has been well supported, but much less emphasis has been given to public health and health systems research. A similar picture is emerging in European support for globalisation and health Case studies Two case-studies illustrate the links of European support in global health research with industry and biomedicine. The European Commission's directorates for (respectively Health, Development and Research held an international conference in Brussels in June 2010. Two of six thematic sessions related to research: one was solely concerned with drug development and the protection of intellectual property. Two European Union-supported health research projects in India show a similar trend. The Euro-India Research Centre was created to support India's participation in EU research programmes, but almost all of the health research projects have been in biotechnology. New INDIGO, a network led by the French national research agency CNRS, has chosen 'Biotechnology and Health' and funded projects only within three laboratory sciences. Discussion Research for commerce supports only one side of economic development. Innovative technologies can be social as well as physical, and be as likely to benefit society and the economy. Global health research agendas to meet the Millenium goals need to prioritise prevention and service delivery. Public interest can be voiced through civil society organisations, able to support social research and public-health interventions. Money for health research comes from public budgets, or indirectly through healthcare costs. European 'Science in Society' programme contrasts research for 'economy', using technical

  3. European health research and globalisation: is the public-private balance right?

    Science.gov (United States)

    McCarthy, Mark

    2011-03-22

    The creation and exchange of knowledge between cultures has benefited world development for many years. The European Union now puts research and innovation at the front of its economic strategy. In the health field, biomedical research, which benefits the pharmaceutical and biotechnology industries, has been well supported, but much less emphasis has been given to public health and health systems research. A similar picture is emerging in European support for globalisation and health Two case-studies illustrate the links of European support in global health research with industry and biomedicine. The European Commission's directorates for (respectively) Health, Development and Research held an international conference in Brussels in June 2010. Two of six thematic sessions related to research: one was solely concerned with drug development and the protection of intellectual property. Two European Union-supported health research projects in India show a similar trend. The Euro-India Research Centre was created to support India's participation in EU research programmes, but almost all of the health research projects have been in biotechnology. New INDIGO, a network led by the French national research agency CNRS, has chosen 'Biotechnology and Health' and funded projects only within three laboratory sciences. Research for commerce supports only one side of economic development. Innovative technologies can be social as well as physical, and be as likely to benefit society and the economy. Global health research agendas to meet the Millenium goals need to prioritise prevention and service delivery. Public interest can be voiced through civil society organisations, able to support social research and public-health interventions. Money for health research comes from public budgets, or indirectly through healthcare costs. European 'Science in Society' programme contrasts research for 'economy', using technical solutions, commercialisation and a passive consumer voice for

  4. European health research and globalisation: is the public-private balance right?

    Science.gov (United States)

    2011-01-01

    Background The creation and exchange of knowledge between cultures has benefited world development for many years. The European Union now puts research and innovation at the front of its economic strategy. In the health field, biomedical research, which benefits the pharmaceutical and biotechnology industries, has been well supported, but much less emphasis has been given to public health and health systems research. A similar picture is emerging in European support for globalisation and health Case studies Two case-studies illustrate the links of European support in global health research with industry and biomedicine. The European Commission's directorates for (respectively) Health, Development and Research held an international conference in Brussels in June 2010. Two of six thematic sessions related to research: one was solely concerned with drug development and the protection of intellectual property. Two European Union-supported health research projects in India show a similar trend. The Euro-India Research Centre was created to support India's participation in EU research programmes, but almost all of the health research projects have been in biotechnology. New INDIGO, a network led by the French national research agency CNRS, has chosen 'Biotechnology and Health' and funded projects only within three laboratory sciences. Discussion Research for commerce supports only one side of economic development. Innovative technologies can be social as well as physical, and be as likely to benefit society and the economy. Global health research agendas to meet the Millenium goals need to prioritise prevention and service delivery. Public interest can be voiced through civil society organisations, able to support social research and public-health interventions. Money for health research comes from public budgets, or indirectly through healthcare costs. European 'Science in Society' programme contrasts research for 'economy', using technical solutions, commercialisation

  5. EurOOHnet-the European research network for out-of-hours primary health care.

    Science.gov (United States)

    Huibers, Linda; Philips, Hilde; Giesen, Paul; Remmen, Roy; Christensen, Morten Bondo; Bondevik, Gunnar Tschudi

    2014-09-01

    European countries face similar challenges in the provision of health care. Demographic factors like ageing, population growth, changing patient behaviour, and lack of work force lead to increasing demands, costs, and overcrowding of out-of-hours (OOH) care (i.e. primary care services, emergency departments (EDs), and ambulance services). These developments strain services and imply safety risks. In the last few decades, countries have been re-organizing their OOH primary health care services. AIM AND SCOPE OF THE NETWORK: We established a European research network for out-of-hours primary health care (EurOOHnet), which aims to transfer knowledge, share experiences, and conduct research. Combining research competencies and integrating results can generate a profound information flow to European researchers and decision makers in health policy, contributing towards feasible and high-quality OOH care. It also contributes to a more comparable performance level within European regions. CONDUCTED RESEARCH PROJECTS: The European research network aims to conduct mutual research projects. At present, three projects have been accomplished, among others concerning the diagnostic scope in OOH primary care services and guideline adherence for diagnosis and treatment of cystitis in OOH primary care. Future areas of research will be organizational models for OOH care; appropriate use of the OOH services; quality of telephone triage; quality of medical care; patient safety issues; use of auxiliary personnel; collaboration with EDs and ambulance care; and the role of GPs in OOH care.

  6. European Business Ethics Network (EBEN) Research Conference 2007

    NARCIS (Netherlands)

    Dommerholt, Egbert

    2007-01-01

    EBEN Research Conference 2007.

    Presentation on the outcomes of two event-studies provided by two sustainability research agencies: Sustainable Asset Management (SAM) and Kinder, Lydenberg and Domini (KLD). The results are included in my PhD thesis report entiteled 'Corporate Sustainabilty

  7. Enabling European Archaeological Research: The ARIADNE E-Infrastructure

    NARCIS (Netherlands)

    Hollander, H.S.; Aloia, Nicola; Binding, Ceri; Cuy, Sebastian; Doerr, Martin; Fanini, Bruno; Felicetti, Achille; Fihn, Johan; Gavrilis, Dimitris; Geser, Guntram; Meghini, Carlo; Niccolucci, Franco; Nurra, Federico; Papatheodorou, Christos; Richards, Julian; Ronzino, Paola; Scopigno, Roberto; Theodoridou, Maria; Theodoridou, Maria; Tudhope, Douglas; Vlachidis, Andreas; Wright, Holly

    2017-01-01

    Research e-infrastructures, digital archives and data services have become important pillars of scientific enterprise that in recent decades has become ever more collaborative, distributed and data-intensive. The archaeological research community has been an early adopter of digital tools for data

  8. Non-European facilities for elementary particle physics research

    International Nuclear Information System (INIS)

    Mann, A.K.

    1983-01-01

    The facilities we now employ in high energy physics cover a broad spectrum of particle energies and intensities and provide therefore a multiplicity of probes with which to study the behavior of elementary particles. In general, the goal has been to achieve ever higher particle energies and intensities, with emphasis on energy, and to develop more versatile and more sensitive detectors with which to study the resultant particle-particle interactions. Most energy regimes that have been explored have yielded new, fundamental information which often becomes clearer and more easily developed when particle energies are further increased. In this talk I shall try to delineate the nature of those facilities in Canada, Japan and the U.S.A. It is useful, I believe, to begin with a brief discussion of the funding and management of facilities in those countries and a short summary of recent history. The main body of the talk concentrates on the present, planned and contemplated facilities of the major non-European accelerator laboratories, and address briefly the status of accelerator development. The concluding section will summarize the salient features of the discussion. (author)

  9. Allergy Relief for Your Child

    Science.gov (United States)

    ... Products For Consumers Home For Consumers Consumer Updates Allergy Relief for Your Child Share Tweet Linkedin Pin ... at the FDA. Avoid Pollen, Mold and Other Allergy Triggers If your child has seasonal allergies, pay ...

  10. Food Allergy: What We Know Now.

    Science.gov (United States)

    Moore, Lindsey E; Stewart, Patricia H; deShazo, Richard D

    2017-04-01

    Food allergy is an adverse immune reaction that occurs reproducibly on exposure to a given food. Prevalence rates of food allergy continue to increase worldwide, sparking continual research efforts in finding a suitable and safe cure. Food avoidance, the current standard of care, can be difficult to achieve. This review aims to provide a broad overview of immunoglobulin E-mediated food allergy, highlighting its epidemiology, masqueraders, immunopathophysiology, clinical presentation, diagnostic work-up and available preventative and treatment strategies. This review also discusses novel, investigative therapies that offer promising therapeutic options, yet require continued research efforts to determine safety effects. Inducing tolerance, whether by immunotherapy or by the administration of monoclonal antibodies, allows us to move toward a cure for food allergy, which could vastly change this field of allergic diseases in the coming decades. Copyright © 2017 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  11. Future development, innovation and promotion of European unique food: an interdisciplinary research framework perspective.

    Science.gov (United States)

    Byrne, Derek V; Waehrens, Sandra S; O'Sullivan, Maurice G

    2013-11-01

    Unique food products constitute a very important element of European food business, culture, identity and heritage. Understanding the uniqueness of food in Europe from a research-based interdisciplinary perspective will be a critical factor in promoting the competitiveness of artisanal food industries going forward both locally and internationally. Success will support the competitiveness of the European food industry, in particular, small and medium enterprises, by enabling substantial product differentiation potential for producers and providing ample variety in food choice for the consumer. In addition, it will contribute to promotion of sustainable agriculture and development of rural areas, protecting them from depopulation. In order to meet the demands of a developing fundamental shift in European Union agricultural focus to greener, sustainable farming practices and wider rural development and to ensure success for local small-scale producers, this paper discusses the future direction of research in the field of unique European foods. The paper presents a perspective which promotes optimisation and innovation in unique food products in Europe through the integration of advanced knowledge and technologies. A framework is presented covering location, identity, perception and well-being as research areas needing synergy to bridge the research knowledge deficit in determination and specification of food identity in the European Union. The ultimate aim being promotion of sustainable agriculture and rural development, particularly in territories across the European Union where unique food is strategically and scientifically under-defined. © 2013 Society of Chemical Industry.

  12. Food Allergy

    Science.gov (United States)

    ... Relations Cyber Infrastructure Computational Biology Equal Employment Opportunity Ethics Global Research Office of Mission Integration and Financial Management Strategic Planning Workforce Effectiveness Workplace Solutions Technology Transfer Intellectual Property Division of AIDS ...

  13. Asthma, Allergies and Pregnancy

    Science.gov (United States)

    ... and immunology. © 2018 American Academy of Allergy, Asthma & Immunology. All Rights Reserved. Legal Notices | Site ... navigation Find an Allergist/Immunologist Search Your Symptoms Ask the Expert

  14. Report of the 1st meeting of the "Vienna Initiative to Save European Academic Research (VISAER)".

    Science.gov (United States)

    Druml, Christiane; Singer, Ernst A; Wolzt, Michael

    2006-04-01

    The European Directive 2001/20/EC ("Clinical Trials Directive") was aimed at simplifying and harmonising European clinical research. The directive's attempt represents an important step because many European Member States lack national laws that specifically address details of research, but the goal has been only partly achieved. For academic investigators doing national or multi-national research the new European law and the requirements following its implementation are likely to have the opposite effect. Some areas seem to be of particular concern: trial sponsorship, the ethical review process, the participation of patients who are temporarily not able to consent in clinical trials, in particular the informed consent process, an accepted European registry for all clinical trials, insurance and pharmacovigilance. Furthermore there are fundamental problems of the conduct of clinical trials that could have been foreseen at the time of implementation of the new law, which are impeding academic basic clinical research. The bureaucratic burden for academic investigators has tremendously increased without representing any contribution to patients' safety or to the scientific value of research. Furthermore some large European academic trials cannot be conducted anymore due to the new regulations. This result in a reduction in the number of trials and additionally in a reduction in the number of patients enrolled in a study. European research and thus European patients will suffer from the loss of potential benefits of research. The Vienna Initiative to Save European Academic Research (VISEAR) brings together leading stakeholders from academic research groups and interested parties from industry, international organisations and regulatory authorities to focus on the issues of concern regarding the organisational and funding of academic clinical research in order to improve the development and use of medicines in Europe. The first step of the initiative was a meeting held

  15. European Bioinformatics Institute: Research Infrastructure needed for Life Science

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    The life science community is an ever increasing source of data from increasing diverse range of instruments and sources. EMBL-EBI has a remit to store and exploit this data, collected and made available openly across the world, for the benefit of the whole research community. The research infrastructure needed to support the big data analysis around this mission encompasses high performance networks, high-throughput computing, and a range of cloud and storage solutions - and will be described in the presentation.

  16. EAACI Guidelines on allergen immunotherapy: IgE-mediated food allergy.

    Science.gov (United States)

    Pajno, G B; Fernandez-Rivas, M; Arasi, S; Roberts, G; Akdis, C A; Alvaro-Lozano, M; Beyer, K; Bindslev-Jensen, C; Burks, W; Ebisawa, M; Eigenmann, P; Knol, E; Nadeau, K C; Poulsen, L K; van Ree, R; Santos, A F; du Toit, G; Dhami, S; Nurmatov, U; Boloh, Y; Makela, M; O'Mahony, L; Papadopoulos, N; Sackesen, C; Agache, I; Angier, E; Halken, S; Jutel, M; Lau, S; Pfaar, O; Ryan, D; Sturm, G; Varga, E-M; van Wijk, R G; Sheikh, A; Muraro, A

    2018-04-01

    Food allergy can result in considerable morbidity, impairment of quality of life, and healthcare expenditure. There is therefore interest in novel strategies for its treatment, particularly food allergen immunotherapy (FA-AIT) through the oral (OIT), sublingual (SLIT), or epicutaneous (EPIT) routes. This Guideline, prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Task Force on Allergen Immunotherapy for IgE-mediated Food Allergy, aims to provide evidence-based recommendations for active treatment of IgE-mediated food allergy with FA-AIT. Immunotherapy relies on the delivery of gradually increasing doses of specific allergen to increase the threshold of reaction while on therapy (also known as desensitization) and ultimately to achieve post-discontinuation effectiveness (also known as tolerance or sustained unresponsiveness). Oral FA-AIT has most frequently been assessed: here, the allergen is either immediately swallowed (OIT) or held under the tongue for a period of time (SLIT). Overall, trials have found substantial benefit for patients undergoing either OIT or SLIT with respect to efficacy during treatment, particularly for cow's milk, hen's egg, and peanut allergies. A benefit post-discontinuation is also suggested, but not confirmed. Adverse events during FA-AIT have been frequently reported, but few subjects discontinue FA-AIT as a result of these. Taking into account the current evidence, FA-AIT should only be performed in research centers or in clinical centers with an extensive experience in FA-AIT. Patients and their families should be provided with information about the use of FA-AIT for IgE-mediated food allergy to allow them to make an informed decision about the therapy. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  17. The Jamaica asthma and allergies national prevalence survey: rationale and methods

    Directory of Open Access Journals (Sweden)

    Edwards Nancy C

    2010-04-01

    Full Text Available Abstract Background Asthma is a significant public health problem in the Caribbean. Prevalence surveys using standardized measures of asthma provide valid prevalence estimates to facilitate regional and international comparisons and monitoring of trends. This paper describes methods used in the Jamaica Asthma and Allergies National Prevalence Survey, challenges associated with this survey and strategies used to overcome these challenges. Methods/Design An island wide, cross-sectional, community-based survey of asthma, asthma symptoms and allergies was done among adults and children using the European Community Respiratory Health Survey Questionnaire for adults and the International Study of Asthma and Allergies in Children. Stratified multi-stage cluster sampling was used to select 2, 163 adults aged 18 years and older and 2, 017 children aged 2-17 years for the survey. The Kish selection table was used to select one adult and one child per household. Data analysis accounted for sampling design and prevalence estimates were weighted to produce national estimates. Discussion The Jamaica Asthma and Allergies National Prevalence Survey is the first population- based survey in the Caribbean to determine the prevalence of asthma and allergies both in adults and children using standardized methods. With response rates exceeding 80% in both groups, this approach facilitated cost-effective gathering of high quality asthma prevalence data that will facilitate international and regional comparison and monitoring of asthma prevalence trends. Another unique feature of this study was the partnership with the Ministry of Health in Jamaica, which ensured the collection of data relevant for decision-making to facilitate the uptake of research evidence. The findings of this study will provide important data on the burden of asthma and allergies in Jamaica and contribute to evidence-informed planning of comprehensive asthma management and education programs.

  18. Enabling European Archaeological Research: The ARIADNE E-Infrastructure

    Directory of Open Access Journals (Sweden)

    Nicola Aloia

    2017-03-01

    Full Text Available Research e-infrastructures, digital archives and data services have become important pillars of scientific enterprise that in recent decades has become ever more collaborative, distributed and data-intensive. The archaeological research community has been an early adopter of digital tools for data acquisition, organisation, analysis and presentation of research results of individual projects. However, the provision of e-infrastructure and services for data sharing, discovery, access and re-use has lagged behind. This situation is being addressed by ARIADNE: the Advanced Research Infrastructure for Archaeological Dataset Networking in Europe. This EU-funded network has developed an e-infrastructure that enables data providers to register and provide access to their resources (datasets, collections through the ARIADNE data portal, facilitating discovery, access and other services across the integrated resources. This article describes the current landscape of data repositories and services for archaeologists in Europe, and the issues that make interoperability between them difficult to realise. The results of the ARIADNE surveys on users' expectations and requirements are also presented. The main section of the article describes the architecture of the e-infrastructure, core services (data registration, discovery and access and various other extant or experimental services. The on-going evaluation of the data integration and services is also discussed. Finally, the article summarises lessons learned, and outlines the prospects for the wider engagement of the archaeological research community in sharing data through ARIADNE.

  19. Contact Allergy in Danish Healthcare Workers

    DEFF Research Database (Denmark)

    Schwensen, Jakob F; Menné, Torkil; Sommerlund, Mette

    2016-01-01

    Contact dermatitis in healthcare workers is a pan-European problem. We conducted a retrospective observational study of the patch-test results of 1402 healthcare workers and 1402 matched controls with contact dermatitis who were treated at 3 hospitals departments in Denmark between 2007 and 2014....... The primary objective was to determine whether healthcare work was associated with contact allergy to thiuram mix. Unadjusted univariate analyses revealed that healthcare work was significantly associated with occupational contact dermatitis and hand dermatitis. Contact allergy to thiuram mix was more common...... in healthcare workers was significantly associated with having occupational contact dermatitis, hand dermatitis and older age. In conclusion, we report here a potential problem of contact allergy to thiurams in healthcare workers with contact dermatitis. Legislative authorities may in the future focus...

  20. Environmental health research in the UK and European Union : research priorities in water and air pollution control

    Energy Technology Data Exchange (ETDEWEB)

    Ince, M; Wheatley, A [Loughborough Univ. of Technology (United Kingdom). Dept. of Civil Engineering

    1997-12-31

    The contents are involvement of the European community, integration of research and development programmes ; surface water quality and pollution incidents; surface water pollution in the UK ; eutrophication ; drinking water quality ; causes and current treatment for removal of pollutants ; future causes of water pollution ; and , water and wastewater research.

  1. Environmental health research in the UK and European Union : research priorities in water and air pollution control

    International Nuclear Information System (INIS)

    Ince, M.; Wheatley, A.

    1996-01-01

    The contents are involvement of the European community, integration of research and development programmes ; surface water quality and pollution incidents; surface water pollution in the UK ; eutrophication ; drinking water quality ; causes and current treatment for removal of pollutants ; future causes of water pollution ; and , water and wastewater research

  2. Analysis of the European CCS research and innovation landscape

    OpenAIRE

    FIORINI ALESSANDRO; PASIMENI FRANCESCO; GEORGAKAKI ALIKI; TZIMAS EVANGELOS

    2016-01-01

    CO2 emissions from fuel combustion have more than doubled in the past 40 years. For this reason, a forward-looking approach to carbon capture and storage (CCS) for the power and industrial sectors is considered as critical to reaching the 2050 climate objectives in a cost-effective way and listed among the research and innovation priorities of the Energy Union. The purpose of this paper is to provide an indicator-based description of the CCS research and innovation landscape in Europe. Partic...

  3. A harmonized and efficient clinical research environment would benefit patients and enhance European competitiveness. Commentary.

    Science.gov (United States)

    Amato, Antonino; Aringhieri, Eugenio; Boccia, Stefania; Buccella, Filippo; Gorini, Barbara; Gramaglia, Donatella; Masetti, Riccardo; Rossi, Paolo; Pelicci, Pier Giuseppe

    2017-01-01

    The forthcoming implementation of the European Clinical Trial Regulation (Regulation (EU) No. 536/2014), which is expected to facilitate the conduct of clinical trials across the European Union, will require National Authorities to create the best conditions for the implementation of the new Regulation through national guidelines, so that sponsors may reconsider Europe as a prime location for planning clinical trials. During a meeting titled "Innovation in Clinical Research", an expert panel discussed potential local advances fostering competitiveness of European clinical research with representatives of the pharmaceutical industry, patient organisations and Italian regulatory agency in view of the forthcoming implementation of (EU) No. 536/2014 on clinical trials of medicinal products. In this article we summarise the findings of the meeting, describe features characterising clinical research patterns and offer some suggestions on the possible involvement of all stakeholders in order to foster research innovation and allow the timely access to novel medicines for patients.

  4. A European collaboration research programme to study and test large scale base isolated structures

    International Nuclear Information System (INIS)

    Renda, V.; Verzeletti, G.; Papa, L.

    1995-01-01

    The improvement of the technology of innovative anti-seismic mechanisms, as those for base isolation and energy dissipation, needs of testing capability for large scale models of structures integrated with these mechanisms. These kind experimental tests are of primary importance for the validation of design rules and the setting up of an advanced earthquake engineering for civil constructions of relevant interest. The Joint Research Centre of the European Commission offers the European Laboratory for Structural Assessment located at Ispra - Italy, as a focal point for an international european collaboration research programme to test large scale models of structure making use of innovative anti-seismic mechanisms. A collaboration contract, opened to other future contributions, has been signed with the national italian working group on seismic isolation (Gruppo di Lavoro sull's Isolamento Sismico GLIS) which includes the national research centre ENEA, the national electricity board ENEL, the industrial research centre ISMES and producer of isolators ALGA. (author). 3 figs

  5. Public relations research: European and international perspectives and innovations

    NARCIS (Netherlands)

    Zerfass, A.; van Ruler, B.; Sriramesh, K.

    2008-01-01

    This volume is a major contribution to the trans-national debate on public relations research and communication management. It presents dominant concepts and findings from the scientific community in Germany in English language. At the same time, the compilation contains a selection of the most

  6. Behavioral Public Administration: Connecting Psychology with European Public Administration Research

    NARCIS (Netherlands)

    Leth Olsen, Asmus; Tummers, L.G.|info:eu-repo/dai/nl/341028274; Grimmelikhuijsen, S.G.|info:eu-repo/dai/nl/313875405; Jilke, Sebastian

    2017-01-01

    Well-known public administration scholars have stressed the importance of psychological research for the study of public administration. Neighboring disciplines such as economics and political science, have witnessed the emergence of the psychology-informed subfields of behavioral economics and

  7. Technology transfer from research and development to European industry

    International Nuclear Information System (INIS)

    Conrads, H.; Theenhaus, R.

    1989-01-01

    This paper gives an overview of technology transfer, i.e. the transfer of knowledge, insights and technologies from research and development to practical application, especially in the Federal Republic of Germany. Some examples and perspectives of technology transfer for nuclear fusion are given. (author). 7 refs.; 5 figs

  8. Pediatric allergy and immunology in China.

    Science.gov (United States)

    Wong, Gary W K; Li, Jing; Bao, Yi-Xiao; Wang, Jiu-Yao; Leung, Ting Fan; Li, Luan-Luan; Shao, Jie; Huang, Xin-Yuan; Liu, En-Mei; Shen, Kun-Ling; Chen, Yu-Zhi

    2018-03-01

    Over the past 30 years, China has enjoyed rapid economic development along with urbanization at a massive scale that the world has not experienced before. Such development has also been associated with a rapid rise in the prevalence of allergic disorders. Because of the large childhood population in the country, the burden of childhood allergic disorders has become one of the major challenges in the healthcare system. Among the Chinese centers participating in the International Study of Asthma and Allergies in Childhood, the data clearly showed a continuing rise in the prevalence of asthma, allergic rhinitis, and atopic eczema. However, the discipline of pediatric allergy in mainland China is still in its infancy due to the lack of formal training program and subspecialty certification. Clinicians and researchers are increasingly interested in providing better care for patients with allergies by establishing pediatric allergy centers in different regions of the country. Many of them have also participated in national or international collaborative projects hoping to answer the various research questions related to the discipline of pediatric allergy and immunology. It is our hope that the research findings from China will not only improve the quality of care of affected children within this country but also the millions of patients with allergies worldwide. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  9. The European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC): experiences from a successful ERS Clinical Research Collaboration.

    Science.gov (United States)

    Chalmers, James D; Crichton, Megan; Goeminne, Pieter C; Loebinger, Michael R; Haworth, Charles; Almagro, Marta; Vendrell, Montse; De Soyza, Anthony; Dhar, Raja; Morgan, Lucy; Blasi, Francesco; Aliberti, Stefano; Boyd, Jeanette; Polverino, Eva

    2017-09-01

    In contrast to airway diseases like chronic obstructive pulmonary disease or asthma, and rare diseases such as cystic fibrosis, there has been little research and few clinical trials in bronchiectasis. Guidelines are primarily based on expert opinion and treatment is challenging because of the heterogeneous nature of the disease. In an effort to address decades of underinvestment in bronchiectasis research, education and clinical care, the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) was established in 2012 as a collaborative pan-European network to bring together bronchiectasis researchers. The European Respiratory Society officially funded EMBARC in 2013 as a Clinical Research Collaboration, providing support and infrastructure to allow the project to grow. EMBARC has now established an international bronchiectasis registry that is active in more than 30 countries both within and outside Europe. Beyond the registry, the network participates in designing and facilitating clinical trials, has set international research priorities, promotes education and has participated in producing the first international bronchiectasis guidelines. This manuscript article the development, structure and achievements of EMBARC from 2012 to 2017. To understand the role of Clinical Research Collaborations as the major way in which the European Respiratory Society can stimulate clinical research in different disease areasTo understand some of the key features of successful disease registriesTo review key epidemiological, clinical and translational studies of bronchiectasis contributed by the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) project in the past 5 yearsTo understand the key research priorities identified by EMBARC for the next 5 years.

  10. European conference on advances in flood research. Vol. 2. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A; Bismuth, C; Menzel, L [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  11. European conference on advances in flood research. Vol. 1. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A; Bismuth, C; Menzel, L [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  12. European conference on advances in flood research. Vol. 1. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A.; Bismuth, C.; Menzel, L. [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  13. European conference on advances in flood research. Vol. 2. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Bronstert, A.; Bismuth, C.; Menzel, L. [eds.

    2000-11-01

    Following concern expressed by several Member States in the 1990's, the EC directorate General of Research and Development (DG XII) has initiated and/or funded a variety of activities in order to improve the scientific basis and to intensify knowledge transfer into practice concerning flood forecasting, risk mitigation, and the impact analysis of environmental change effects. After more then half a decade of research in this field, this conference is aimed to present the results achieved and to highlight the scientific advances. Besides the presentations of the EUROTAS-project results, the contributions are grouped into the following sub-sessions: impact of land use and climate on flooding, flood management and assessment of flood risk, catchment modelling and management systems, and impact of river engineering on flooding conditions. (orig.)

  14. Research fields, challenges and opportunities in European oilseed crops breeding

    Directory of Open Access Journals (Sweden)

    Vincourt Patrick

    2014-11-01

    Full Text Available Due to the geographical specialization in oilseed world production, Europe has a major role to play in winter oilseed rape and sunflower breeding. Mainly based on the most recen t results, this review aims to identify the main research and breeding targets for these two crops, as seen through publications, with an attempt to suggest what are opportunities and challenges in these research fields. Growing a healthy and yielding crop remains the key driver for agronomic production. However sustainability and environmental profiles of the cultivar are now entering the field of play: The sustainability concern invested the field of resistance to diseases. Nitrogen use efficiency became an important target for Brassica napus, and crop resilience toward drought stresses is the way chosen in Helianthus annuus breeding for yield improvement. Significant advances are underway for quality traits, but the uncertainty on nutritional and industrial demand may explain why the product diversification remains low.

  15. European research and the Hungarian school of food irradiation

    Science.gov (United States)

    Lakner, Zoltán; Soós, Sándor; Vida, Zsófia; Farkas, Csilla

    2016-12-01

    In second half of the 20th century the research of application of irradiation to food preservation become a new and prospective field of food science and technology. This activity has been supported and developed in a parallel way in both halves of the that-time world, divided by the iron-curtain. Under these conditions, fulfilling a specific "bridge-role", some highly innovative scientists, first of all Professor József Farkas has been able to achieve considerable results in this new field of science. Based on citation analysis and science mapping it can be proven, that his path-breaking research has been exercise a fertilising effect on development of a wide range of fields of science, and considerably contributed to proliferation of this science and technology in numerous countries of the world.

  16. Towards the "Fifth Freedom": Increasing the Mobility of Researchers in the European Union

    Science.gov (United States)

    Marimon, Ramon; Lietaert, Matthieu; Grigolo, Michele

    2009-01-01

    Many researchers trained in Europe leave to work abroad, namely in the USA. This brain-drain phenomenon is the result of a lack of openness and competition in European academic systems. Some aspects relating to the mobility of academic careers could make a difference in attracting--and maintaining--researchers, aside to serious structural reform.…

  17. Public services in early modern European towns: An agenda for further research

    NARCIS (Netherlands)

    Davids, C.A.

    2010-01-01

    Starting with a set of key questions formulated by Walter Prevenier in 1984, this article proposes an agenda for future research on urban public services in early modern European towns. The author suggests, first of all, a shift in research strategy toward a greater emphasis on actor-oriented

  18. EERA: A participant or an agent in European research policy? A governance perspective

    NARCIS (Netherlands)

    Moos, L.; Wubbels, Theo

    2014-01-01

    In this article, the authors begin to frame a discussion of the educational research space that the European Educational Research Association (EERA) has been given and aims to take. The educational space is not merely a geographical phenomenon, but rather refers to the networks, flows and scapes

  19. Stimulating translational research: several European life science institutions put their heads together.

    Science.gov (United States)

    Bentires-Alj, Mohamed; Rajan, Abinaya; van Harten, Wim; van Luenen, Henri G A M; Kubicek, Stefan; Andersen, Jesper B; Saarela, Janna; Cook, Simon J; Van Minnebruggen, Geert; Roman-Roman, Sergio; Maurer, Cornelia; Erler, Janine T; Bertero, Michela G

    2015-09-01

    Translational research leaves no-one indifferent and everyone expects a particular benefit. We as EU-LIFE (www.eu-life.eu), an alliance of 13 research institutes in European life sciences, would like to share our experience in an attempt to identify measures to promote translational research without undermining basic exploratory research and academic freedom. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Outstanding animal studies in allergy I. From asthma to food allergy and anaphylaxis.

    Science.gov (United States)

    Jensen-Jarolim, Erika; Pali-Schöll, Isabella; Roth-Walter, Franziska

    2017-06-01

    Animal models published within the past 18 months on asthma, food allergy and anaphylaxis, all conditions of rising public health concern, were reviewed. While domestic animals spontaneously develop asthma, food allergy and anaphylaxis, in animal models, divergent sensitization and challenge routes, dosages, intervals and antigens are used to induce asthmatic, food allergic or anaphylactic phenotypes. This must be considered in the interpretation of results. Instead of model antigens, gradually relevant allergens such as house dust mite in asthma, and food allergens like peanut, apple and peach in food allergy research were used. Novel engineered mouse models such as a mouse with a T-cell receptor for house dust mite allergen Der p 1, or with transgenic human hFcγR genes, facilitated the investigation of single molecules of interest. Whole-body plethysmography has become a state-of-the-art in-vivo readout in asthma research. In food allergy and anaphylaxis research, novel techniques were developed allowing real-time monitoring of in-vivo effects following allergen challenge. Networks to share tissues were established as an effort to reduce animal experiments in allergy which cannot be replaced by in-vitro measures. Natural and artificial animal models were used to explore the pathophysiology of asthma, food allergy and anaphylaxis and to improve prophylactic and therapeutic measures. Especially the novel mouse models mimicking molecular aspects of the complex immune network in asthma, food allergy and anaphylaxis will facilitate proof-of-concept studies under controlled conditions.

  1. The diagnosis and management of food allergies. Position paper of the Food Allergy Section the Polish Society of Allergology

    Directory of Open Access Journals (Sweden)

    Zbigniew Bartuzi

    2017-10-01

    Full Text Available The paper concerns the current position of the Polish Society of Allergology Food Allergy Section on the diagnosis and management of food allergies. The aim of this position is to provide evidence-based recommendations on the diagnosis and management of patients with allergic hypersensitivity to foods. This position statement includes a systematic review of studies in three areas, namely, the epidemiology, diagnosis and management of food allergies. While taking into account the specific Polish setting, in this publication we also used the current European Academy of Allergy and Clinical Immunology (EAACI position paper and other current position statements, including those of the United States National Institute of Allergy and Infectious Diseases (NIAID.

  2. Prevention of food allergy - Early dietary interventions.

    Science.gov (United States)

    Du Toit, George; Foong, Ru-Xin M; Lack, Gideon

    2016-10-01

    The prevalence of food allergy has increased over the last 30 years and remains a disease, which significantly impacts on the quality of life of children and their families. Several hypotheses have been formulated to explain the increasing prevalence; this review will focus on the hypothesis that dietary factors may influence the development of food allergy. Historically, the prevention of food allergy has focused on allergen avoidance. However, recent findings from interventional studies have prompted a shift in the mind set from avoidance to early introduction of potentially allergenic foods. This review aims to facilitate a better understanding of contemporary research studies that make use of early introduction of common allergenic foods into infant diets as a preventative strategy against the development of food allergy. Copyright © 2016 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

  3. Die-back of Phragmites australis in European wetlands: an overview of the European Research Programme on Reed Die-Back and Progression (1993-1994)

    NARCIS (Netherlands)

    Van der Putten, W.H.

    1997-01-01

    Reed (Phragmites australis (Cav.) Trin. ex Steudel) is one of the dominant plant species in European land-water ecotones. During the past decades reed belts have died back, especially in central and eastern Europe. The aim of the European Research Programme on Reed Die-back and Progression (EUREED),

  4. Fighting Allergies at School

    Science.gov (United States)

    Taylor, Kelley R.

    2008-01-01

    In the last decade, the number of children diagnosed with food allergies has increased significantly--to an estimated 3 million affected in the United States alone (Food Allergy and Anaphylaxis Network, n.d.). As that number increases, so do the articles, legislation, and policies that are designed to address how to best deal with peanut allergies…

  5. European Union - Space of Regeneration, Learning and Innovation in the Context of Sustainable Multidisciplinary Research

    Directory of Open Access Journals (Sweden)

    Florin Răzvan Bălășescu

    2010-07-01

    Full Text Available Objective The Lisbon Strategy set a new goal for the EU economy: the transition to a knowledge based economy, competitive and sustainable at macro and regional levels, by creating the European Research Area – a geographic area without frontiers for researches, where scientific resources are better managed to create more jobs and improve Europe's competitiveness. That means an interaction between specific and multidisciplinary research network. Approach However, general research methodology sustains the importance of static and revolutionary specific criteria of Scientific Research Programs but also reveals the natural process of multidisciplinary researches. In this context, the European Union could be regarded as a specific and multidisciplinary research area, as a network of flows, connections, relationships, interdependencies, and interferences between natural - experimental and social-humanistic research spheres (economics, management, sociology and complex systems ecology. Prior Work: In this respect some researchers suggested that both natural and social systems could be considered as multidisciplinary complex adaptive systems consisting of specific cluster network connections ( in the form of biotic and abiotic nodes, respectively, the competitive and regional poles with the ability to continuous self-organizing, learning and regenerating process especially in crisis situations. Implications and Value Paper Utility The present paper might be useful to illustrate the contribution of technical-economic and socio-ecological researches to increasing the sustainability framework of European Research Area by considering the transition from the R&D approach (development through research process to the L&D approach (development through learning process.

  6. European Organization for Nuclear Research annual report 1976

    International Nuclear Information System (INIS)

    1977-01-01

    The 1976 CERN annual report begins with a brief history of the organization and description of the organizational structure. A description of the CERN accelerators is given and CERN scientific activities are reviewed. The main body of the report comprises reports from the eleven main divisions, and administrative divisions such as personnel and finance. The reports from the scientific divisions contain descriptions of, and data from, present research and plans for long term development. The appendices contain a list of CERN publications for 1976, a list of lectures and seminars held, a list of training programmes undertaken and a list of scientific conferences and schools held. (B.D.)

  7. Research, Education and Innovation Bundling Forces towards a Sustainable European Energy Future

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    New technologies and applied innovation in the field of sustainable energy are needed in order to achieve a competitive and climate neutral Europe. As one of the first three Knowledge and Innovation Communities (KIC) of the European Institute of Innovation and Technology (EIT), KIC InnoEnergy invests in innovation projects and new educational programmes and provides business creation service with the purpose of delivering the disruptive technologies and innovations that Europe requires to meet this ambitious goal. Its stakeholders are top European players in the industry, research institutes, universities and business schools. Six regionally bundled European hubs – Barcelona/Lisbon, Grenoble, Eindhoven, Karlsruhe, Stockholm and Krakow - lead one thematic field each in sustainable energy. The thematic fields addressed range from Intelligent “Energy-efficient Residential Buildings and Cities” over “Energy from Chemical Fuels”, “Renewable Energies”, “Clean Coal Technologies” to “European Smar...

  8. The importance of international collaboration for rare diseases research: a European perspective.

    Science.gov (United States)

    Julkowska, D; Austin, C P; Cutillo, C M; Gancberg, D; Hager, C; Halftermeyer, J; Jonker, A H; Lau, L P L; Norstedt, I; Rath, A; Schuster, R; Simelyte, E; van Weely, S

    2017-09-01

    Over the last two decades, important contributions were made at national, European and international levels to foster collaboration into rare diseases research. The European Union (EU) has put much effort into funding rare diseases research, encouraging national funding organizations to collaborate together in the E-Rare program, setting up European Reference Networks for rare diseases and complex conditions, and initiating the International Rare Diseases Research Consortium (IRDiRC) together with the National Institutes of Health in the USA. Co-ordination of the activities of funding agencies, academic researchers, companies, regulatory bodies, and patient advocacy organizations and partnerships with, for example, the European Research Infrastructures maximizes the collective impact of global investments in rare diseases research. This contributes to accelerating progress, for example, in faster diagnosis through enhanced discovery of causative genes, better understanding of natural history of rare diseases through creation of common registries and databases and boosting of innovative therapeutic approaches. Several examples of funded pre-clinical and clinical gene therapy projects show that integration of multinational and multidisciplinary expertize generates new knowledge and can result in multicentre gene therapy trials. International collaboration in rare diseases research is key to improve the life of people living with a rare disease.

  9. Referrals to a regional allergy clinic - an eleven year audit

    Directory of Open Access Journals (Sweden)

    Hewson Paul

    2010-12-01

    on average 5 years younger than those with other allergies, and those allergic to nuts were much younger (26 Vs 38 than those with other food allergies. There was clear evidence for spatial clustering with marked clustering around the referral hospital. However, the geographical distribution varied between allergies; airborne (particularly pollen allergies clustered in North Dartmoor and Exmoor, food allergies (particularly nut allergies in the South Hams, and on small numbers, some indication of seafood allergy in the far south west of Cornwall and in the Padstow area. Conclusions This study shows marked geographical differences in allergy referrals which are likely to reflect a combination of environmental factors and GP referral patterns. The data suggest that GPs may benefit from education and ongoing decision support and be supported by public education on the nature of allergy. It suggests further research into what happens to patients with allergy where there has been low use of tertiary services and further research into cross-reactivity and co-occurrence, and spatial distribution of allergy.

  10. European pathways for Slovak research and education in the nuclear power domain

    International Nuclear Information System (INIS)

    Slugen, Vladimir

    2010-01-01

    New approaches of the European Commission (DG RTD Energy) to the development of nuclear power engineering (focussed on fission and reactor systems) through various support programmes, which can be of use also in Slovak conditions, are discussed. The following topics are described in detail: Globalization of European research and education; Competency in the nuclear power domain; EU platforms for directing EURATOM research activities (SET, SNE-TP, ENEF, ENSREG); ENEN, EHRO-N, ENELA and their position in European education; Objectives of EURATOM research and professional training programmes; Focus on the creation of competencies serving the nuclear sector at the EU level (ECVET); and Towards mutual recognition of nuclear competencies new EURATOM educational programmes in the domain of fission (examples of EFTS: TRASNUSAFE, ENEN III, ENETRAP II, PETRUS II). (orig.)

  11. Immunology of Food Allergy.

    Science.gov (United States)

    Tordesillas, Leticia; Berin, M Cecilia; Sampson, Hugh A

    2017-07-18

    Many consider food allergy as the "second wave" of the allergy epidemic following the "first wave" of respiratory allergy, i.e., asthma and allergic rhinitis, plaguing westernized countries, with up to 8% of young children and 2%-3% of adults in the United States now affected by hypersensitivity reactions to various foods. In the past decade, there have been great strides in our understanding of the underlying immunopathogenesis of these disorders, which have led to improved diagnostic techniques, management strategies, and therapeutic approaches. Here we will review the most recent understanding of basic mechanisms underlying IgE-mediated food allergies and novel therapeutic approaches under investigation for both the prevention and treatment of IgE-mediated food allergies. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Proceedings of the European Review Meeting on Severe Accident Research - ERMSAR 2005

    International Nuclear Information System (INIS)

    2005-01-01

    The SARNET network has been set up under the aegis of the Framework Programmes (FP) of the European Commission on research. Two projects have been defined, both coordinated by IRSN (France), in the FP6 (2004-08) and FP7 (2009-13), with the following key objectives: Improving knowledge on severe accidents (SA) in order to reduce the uncertainties on the pending issues, thereby enhancing the plant safety, Coordinating research resources and expertise available in Europe, Preserving the research data and disseminating knowledge. The network members commit to contribute to a Joint Programme of Activities that can be broken into several elements: - Implementing an advanced communication tool for fostering exchange of information; - Harmonizing and re-orienting the research programmes, and defining commonly new ones; - Analysing commonly the experimental results provided by research programmes in order to elaborate a common understanding of concerned phenomena; - Developing ASTEC, which capitalizes in terms of models the knowledge produced within SARNET; - Developing Scientific Databases, in which all the results of research programmes are stored; - Developing a common methodology for Probabilistic Safety Assessment (PSA) of NNPs; - Developing educational courses and text (source) books; - Promoting personnel mobility between the various European organisations. SARNET provides an appropriate frame for achieving within a couple of years a sustainable integration of the European research capacities on SA. By capitalizing the acquired knowledge in ASTEC and in Scientific Databases, SARNET produces necessary conditions for preserving the knowledge produced by thousands of men-years and diffusing it to a large number of end-users. By fostering collaborative work on developing and validating ASTEC, SARNET makes this code as the European reference for any kind of water-cooled NPP existing in Europe. By fostering collaborative work in the domain of code development and PSA

  13. EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy

    Directory of Open Access Journals (Sweden)

    Calderon Moises A

    2012-10-01

    Full Text Available Abstract Allergy today is a public health concern of pandemic proportions, affecting more than 150 million people in Europe alone. In view of epidemiological trends, the European Academy of Allergy and Clinical Immunology (EAACI predicts that within the next few decades, more than half of the European population may at some point in their lives experience some type of allergy. Not only do allergic patients suffer from a debilitating disease, with the potential for major impact on their quality of life, career progression, personal development and lifestyle choices, but they also constitute a significant burden on health economics and macroeconomics due to the days of lost productivity and underperformance. Given that allergy triggers, including urbanization, industrialization, pollution and climate change, are not expected to change in the foreseeable future, it is imperative that steps are taken to develop, strengthen and optimize preventive and treatment strategies. Allergen specific immunotherapy is the only currently available medical intervention that has the potential to affect the natural course of the disease. Years of basic science research, clinical trials, and systematic reviews and meta-analyses have convincingly shown that allergen specific immunotherapy can achieve substantial results for patients, improving the allergic individuals’ quality of life, reducing the long-term costs and burden of allergies, and changing the course of the disease. Allergen specific immunotherapy not only effectively alleviates allergy symptoms, but it has a long-term effect after conclusion of the treatment and can prevent the progression of allergic diseases. Unfortunately, allergen specific immunotherapy has not yet received adequate attention from European institutions, including research funding bodies, even though this could be a most rewarding field in terms of return on investments, translational value and European integration and, a field in

  14. 75 FR 18510 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Science.gov (United States)

    2010-04-12

    ... Institute of Allergy and Infectious Diseases Special Emphasis Panel; NIAID Clinical Trial Planning (R34... Assistance Program Nos. 93.855, Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and...

  15. Overview of decommissioning research and development activities in the European Community

    International Nuclear Information System (INIS)

    Huber, B.

    1982-01-01

    The European Community's research program on the decommissioning of nuclear power plants is managed by the Commission of the European Communities and carried out by national laboratories and private firms under cost-sharing contracts. Starting in 1980, about fifty research contracts covering a large variety of topics have been let so far. The paper outlines the content, progress and selected results of the seven projects composing the program. These projects concern the following subjects: maintaining disused plants in a safe condition; decontamination for decommissioning purposes; dismantling techniques; treatment of waste materials; large waste containers; estimation of waste arisings; and plant design features facilitating decommissioning. 4 references

  16. EU FP7 project 'CAMbrella' to build European research network for complementary and alternative medicine

    DEFF Research Database (Denmark)

    Weidenhammer, Wolfgang; Lewith, George; Falkenberg, Torkel

    2011-01-01

    BACKGROUND: The status of complementary and alternative medicine (CAM) within the EU needs clarification. The definition and terminology of CAM is heterogeneous. The therapies, legal status, regulations and approaches used vary from country to country but there is widespread use by EU citizens...... governing CAM provision, and to explore the needs and attitudes of EU citizens with respect to CAM. Based on this information a roadmap will be created that will enable sustainable and prioritised future European research in CAM. CAMbrella encompasses 16 academic research groups from 12 European countries...... review open access publications and a final conference, with emphasis on current and future EU policies, addressing different target audiences....

  17. For the Anniversary Edition of the Scientific Journal European Researcher. Series A – 110 issue

    OpenAIRE

    Goran Rajović; JelisavkaBulatović

    2016-01-01

    This article is a review of the jubilee scientific journal "European Researcher. Series A ", marked at all in 2016 – the sixth anniversary, of regular and of continuous publication. In addition to the history of the newspaper are exposed to the development phase of its program concept. The journal is the period 2010 – 2016 year, profiled in an important factor of development and the formation of professional and scientific thought. Journal “European Research. Series A” is now open forum for p...

  18. European Fusion Materials Research Program - Recent Results and Future Strategy

    International Nuclear Information System (INIS)

    Diegele, E.; Andreani, R.; Laesser, R.; Schaaf, B. van der

    2005-01-01

    The paper reviews the objectives and the status of the current EU long-term materials program. It highlights recent results, discusses some of the key issues and major existing problems to be resolved and presents an outlook on the R and D planned for the next few years. The main objectives of the Materials Development program are the development and qualification of reduced activation structural materials for the Test Blanket Modules (TBMs) in ITER and of low activation structural materials resistant to high fluence neutron irradiation for in-vessel components such as breeding blanket, divertor and first wall in DEMO. The EU strategy assumes: (i) ITER operation starting in 2015 with DEMO relevant Test Blanket Modules to be installed from day one of operation, (ii) IFMIF operation in 2017 and (iii) DEMO final design activities in 2022 to 2025. The EU candidate structural material EUROFER for TBMs has to be fully code qualified for licensing well before 2015. In parallel, research on materials for operation at higher temperatures is conducted following a logical sequence, by supplementing EUROFER with the oxide dispersion strengthened ferritic steels and, thereafter, with fibre-reinforced Silicon Carbide (SiC f /SiC). Complementary, tungsten alloys are developed as structural material for high temperature applications such as gas-cooled divertors

  19. INITIAL ALLERGY PREVENTION IN CHILDREN

    Directory of Open Access Journals (Sweden)

    A.N. Pampura

    2009-01-01

    Full Text Available Allergy prevention is an urgent pediatric issue. Food allergy spread among infants amounts to 6–8%. This review highlights the modern viewpoints on diet prevention of this pathology among children, including by means of the hypoallergic nutritional formulas.Key words: food allergy, prevention, allergies, prebiotics, children.

  20. Cancer registration, public health and the reform of the European data protection framework: Abandoning or improving European public health research?

    Science.gov (United States)

    Andersen, Mette Rye; Storm, Hans H

    2015-06-01

    The importance of cancer- and other disease registries for planning, management and evaluation of healthcare systems has been shown repeatedly during the last 50 years. Complete and unbiased population-level analyses on routinely collected, individual data concerning health and personal characteristics can address significant concerns about risk factors for cancer and provide sound evidence about public health and the effectiveness of healthcare systems. The existence of quality controlled and comprehensive data in registries, allowed to be used for quality control, research and public health purposes are taken as granted by most health professionals and researchers. However, the current revision of the European Union (EU) data protection framework suggests a harmonisation of requirements for confidentiality and individual consent to data processing, likely at the expense of proper use of registry data in the health sector. Consequences of excessive confidentiality rules that may lead to missed data linkages have been simulated. The simulations provide one possible explanation for observed heterogeneity among some cancer incidence data. Further, public health, quality control and epidemiological research on large populations can no longer provide evidence for health interventions, if requirements for consent renders research impossible or where attempts to obtain consent from each data subject generates biased results. Health professionals should engage in the on-going debate on the Commission's proposal for a General Data Protection Regulation. The nature and use of registry data in public health research must be explained and known to policy-makers and the public. Use of cancer registry data and other epidemiological activity will terminate abruptly if an unnecessarily strict EU data protection regulation is adopted. Research based interventions, as well as the international recognised standing of cancer registries and register-based research institutions in

  1. The European Research Agenda for career guidance and counseling - and beyond. ECADOC - Early stage researchers symposium 2016

    DEFF Research Database (Denmark)

    Thomsen, Rie; Weber, Peter C.

    Research in CGC is an expanding field of research still it is important to attract doctoral candidates to commit themselves to participation in scholarly exchange at central conferences. IAEVG is a central conference to the research field of Career Guidance and Counseling. With this symposium we...... to present their research in progress and to open up for discussion on the inclusion process into the research field of CGC. The Early stage researchers symposium 2016 includes work in progress presentations 1) the European Research Agenda 2) recognition in adult education and the role of guidance, 3......) quality in career guidance, 4) an ESR experience of entering the CGC research community. The symposium will support and encourage Early stage researchers participation in the international career guidance research community and allow for symposium participants to hear about the newest research ideas...

  2. The European water framework directive: A challenge for nearshore, coastal and continental shelf research

    Science.gov (United States)

    Borja, Ángel

    2005-09-01

    The European Water Framework Directive (WFD) establishes a framework for the protection of groundwater, inland surface waters, estuarine waters, and coastal waters. The WFD constitutes a new view of the water resources management in Europe because, for the first time, water management is: (i) based mainly upon biological and ecological elements, with ecosystems being at the centre of the management decisions; (ii) applied to European water bodies, as a whole; and (iii) based upon the whole river basin, including also the adjacent coastal area. Although the marine water bodies affected by the WFD relate to only 19.8% of the whole of the European continental shelf, its application constitutes a challenge and an opportunity in nearshore, coastal and continental shelf research. This contribution highlights some of the main tasks and the research to be undertaken in the coming years, proposing investigations into: typologies; physico-chemical processes; indicator species; reference conditions; integration of the quality assessment; methodologies in determining ecological status, etc.

  3. Pediatric allergy and immunology in Israel.

    Science.gov (United States)

    Geller-Bernstein, Carmi; Etzioni, Amos

    2013-03-01

    After the geographic and sociodemographic settings as well as the health care in Israel are briefly described, the scope of pediatric allergy and immunology in Israel is presented. This includes specific disorders commonly encountered, the environment that induces symptoms, the specialists who treat them, and the common challenges of patients, parents, doctors, and allied health personnel who collaborate to manage the maladies and patient care. Allergies usually affect some overall 15-20% of the pediatric population. The main allergens are inhaled, ingested, or injected (insects stings). Generally, the incidence of the various allergens affecting children in Israel, is similar to other parts of the Western world. Owing to the high consanguinity rate in the Israeli population, the prevalence of the various immunodeficiency conditions (in the adaptive as well as the innate system) is higher than that reported worldwide. Pediatric allergists/immunologists also treat autoimmune disorders affecting the pediatric group. Pediatric allergy and clinical immunology are not separate specialties. The 25 specialists who treat children with allergic/immunologic diseases have undergone a basic training in Pediatrics. They also received an additional 2-yr training in allergy and clinical immunology and then have to pass the board examinations. They work mainly in pediatric allergy units, in several hospitals that are affiliated to the five medical schools in the country. Aside from clinical work, most of the centers are also heavily involved in clinical and basic research in allergy and immunology. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

  4. Management of Food Allergy

    Directory of Open Access Journals (Sweden)

    Sh Maleknejad

    2014-04-01

    Full Text Available Although food allergy is a major public health problem, currently there is no effective and safe treatment except to avoid the foods .But the need for new options is critical now as the number of children diagnosed with food allergies rises. Avoiding the offending allergen in the diet is the primary treatment of food allergy. Once a food to which the patient is sensitive has been identified, the food must be removed from the diet. People with severe food allergies must be prepared to treat an anaphylactic reaction. These individuals also always should carry a syringe of adrenaline (epinephrine [EpiPen], and be prepared to self-administer it if they think they are developing an allergic reaction. Several medications are available for treating the other symptoms of food allergy. For example, antihistamines can relieve gastrointestinal symptoms, hives, sneezing, and a runny nose. Bronchodilators can relieve the symptoms of asthma. They are not effective, however, in preventing an allergic reaction when taken prior to eating the food. In fact, no medication in any form is available to reliably prevent an allergic reaction to a certain food before eating that food.Novel therapeutic approaches to food allergy can be classified as food allergen-specific therapy(immunotherapy with native or modified recombinant allergens, or oral desensitization or food allergen-nonspecifictherapy (anti-IgE, traditional Chinese medicine.   Key Words: Children, Food Allergy, Management.  

  5. The European Fusion Research and Development Programme and the ITER Project

    International Nuclear Information System (INIS)

    Green, B J

    2006-01-01

    The EURATOM fusion research and development programme is a well integrated and coordinated programme. It has the objective of ''developing the technology for a safe, sustainable, environmentally responsible and economically viable energy source.'' The programme is focussed on the magnetic confinement approach and supports 23 Associations which involve research entities (many with experimental and technology facilities) each having a bilateral contractual relationship with the European Commission. The paper will describe fusion reactions and present their potential advantages as an energy source. Further, it will describe the EURATOM programme and how it is organised and implemented. The success of the European programme and that of other national programmes, have provided the basis for the international ITER Project, which is the next logical step in the development of fusion energy. The paper will describe ITER, its aims, its design, and the supporting manufacture of prototype components. The European contribution to ITER, the exploitation of the Joint European Torus (JET), and the long-term reactor technology R and D are carried out under the multilateral European Fusion Development Agreement (EFDA)

  6. Innovations in Doctoral Training and Research on Tinnitus: The European School on Interdisciplinary Tinnitus Research (ESIT) Perspective.

    Science.gov (United States)

    Schlee, Winfried; Hall, Deborah A; Canlon, Barbara; Cima, Rilana F F; de Kleine, Emile; Hauck, Franz; Huber, Alex; Gallus, Silvano; Kleinjung, Tobias; Kypraios, Theodore; Langguth, Berthold; Lopez-Escamez, José A; Lugo, Alessandra; Meyer, Martin; Mielczarek, Marzena; Norena, Arnaud; Pfiffner, Flurin; Pryss, Rüdiger C; Reichert, Manfred; Requena, Teresa; Schecklmann, Martin; van Dijk, Pim; van de Heyning, Paul; Weisz, Nathan; Cederroth, Christopher R

    2017-01-01

    Tinnitus is a common medical condition which interfaces many different disciplines, yet it is not a priority for any individual discipline. A change in its scientific understanding and clinical management requires a shift toward multidisciplinary cooperation, not only in research but also in training. The European School for Interdisciplinary Tinnitus research (ESIT) brings together a unique multidisciplinary consortium of clinical practitioners, academic researchers, commercial partners, patient organizations, and public health experts to conduct innovative research and train the next generation of tinnitus researchers. ESIT supports fundamental science and clinical research projects in order to: (1) advancing new treatment solutions for tinnitus, (2) improving existing treatment paradigms, (3) developing innovative research methods, (4) performing genetic studies on, (5) collecting epidemiological data to create new knowledge about prevalence and risk factors, (6) establishing a pan-European data resource. All research projects involve inter-sectoral partnerships through practical training, quite unlike anything that can be offered by any single university alone. Likewise, the postgraduate training curriculum fosters a deep knowledge about tinnitus whilst nurturing transferable competencies in personal qualities and approaches needed to be an effective researcher, knowledge of the standards, requirements and professionalism to do research, and skills to work with others and to ensure the wider impact of research. ESIT is the seed for future generations of creative, entrepreneurial, and innovative researchers, trained to master the upcoming challenges in the tinnitus field, to implement sustained changes in prevention and clinical management of tinnitus, and to shape doctoral education in tinnitus for the future.

  7. Radioactive waste management: outline of the research programme of the Commission of the European Communities

    International Nuclear Information System (INIS)

    Bresesti, M.

    1980-01-01

    The lines of activity, the main achievements and the perspectives of the research programme of the Commission of the European Communities on radioactive waste management, are presented. In particular an overall view of the activity on chemical separation and nuclear transmutation of actinides is given, as introduction to the various presentations of the JRC staff on specific aspects of this waste management strategy

  8. Giving in Europe : The state of research on giving in 20 European countries

    NARCIS (Netherlands)

    Hoolwerf, L.K.; Schuyt, T.N.M.

    2017-01-01

    This study is in intitial attempt to map philanthropy in Europe and presents a first overall estimation of the European philanthropic sector. Containing an overview of what we know about research on the philanthropy sector, it provides data and and assesment of the data on giving by households,

  9. Food-related lifestyles in Singapore: Testing a Western European research instrument in Southeast Asia

    DEFF Research Database (Denmark)

    Askegaard, Søren; Brunsø, Karen; Crippen, Kaye

    The food-realaed life style instrument developed by the MAPP research group has, up till now, been applied mainly in the context of European cultures. The purpose of the present study is to apply the food-related life style instrument in a new and different cultural setting, to compare results, a...

  10. In Pursuit of Excellence? Discursive Patterns in European Higher Education Research

    Science.gov (United States)

    Ramirez, Francisco O.; Tiplic, Dijana

    2014-01-01

    European higher education is awash with educational reform initiatives that purport to transform universities into better-managed higher quality organizations that more directly contribute to national development. This exploratory study examines patterns of research discourse in higher education in Europe. We argue that these patterns are changing…

  11. Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI)

    DEFF Research Database (Denmark)

    Maas, Andrew I R; Menon, David K; Steyerberg, Ewout W

    2015-01-01

    in process and clinical care. Results will be integrated with living systematic reviews in a process of knowledge transfer. The study initiation was from October to December 2014, and the recruitment period was for 18 to 24 months. EXPECTED OUTCOMES: Collaborative European NeuroTrauma Effectiveness Research...

  12. The Rijksherbarium and its contribution to the research on the Netherlands and European flora

    NARCIS (Netherlands)

    Mennema, J.

    1979-01-01

    In the first decades of its existence the interest of the Rijksherbarium was certainly not directed towards the study of the Dutch and European flora. The initiative to embark on research of the flora of the Netherlands was born outside the walls of the institute. In 1845, R. B. van den Bosch

  13. Administrative History of the European Office of Aerospace Research and Development from 1952 through 1975

    Science.gov (United States)

    2012-06-01

    than would an equal expenditure in the domestic market contributed to the expansion of the European Office program by the end of 1956. The fact that...ore1gn researc • On 22 March 1968, the DCS/Research and Development’s (USAF) Assistant for Foreign Development inserted himself into the discussions

  14. European Society of Gastrointestinal Endoscopy - Establishing the key unanswered research questions within gastrointestinal endoscopy

    DEFF Research Database (Denmark)

    Rees, Colin J; Ngu, Wee Sing; Regula, Jaroslaw

    2016-01-01

    Background and study aim: Gastrointestinal endoscopy is a rapidly evolving research field. The European Society of Gastrointestinal Endoscopy (ESGE) plays a key role in shaping opinion and endoscopy activity throughout Europe and further afield. Establishing key unanswered questions within the fi...

  15. School Choice Research in Five European Countries: The Circulation of Stephen Ball's Concepts and Interpretations

    Science.gov (United States)

    van Zanten, Agnès; Kosunen, Sonja

    2013-01-01

    This article analyzes the influence of Stephen Ball's work on research on markets and school choice in five European countries (Finland, France, Norway, Spain, and Sweden). The main focus is on the intellectual circulation of ideas, but the authors also take into account the relationship between ideas and social and political changes, as well as…

  16. TRANSAUTOPHAGY : European network for multidisciplinary research and translation of autophagy knowledge

    NARCIS (Netherlands)

    Casas, Caty; Codogno, Patrice; Pinti, Marcello; Batoko, Henri; Morán, María; Proikas-Cezanne, Tassula; Reggiori, Fulvio; Sirko, Agnieszka; Soengas, María S; Velasco, Guillermo; Lafont, Frank; Lane, Jon; Faure, Mathias; Cossarizza, Andrea

    2016-01-01

    A collaborative consortium, named "TRANSAUTOPHAGY," has been created among European research groups, comprising more than 150 scientists from 21 countries studying diverse branches of basic and translational autophagy. The consortium was approved in the framework of the Horizon 2020 Program in

  17. Microbiome/microbiota and allergies.

    Science.gov (United States)

    Inoue, Yuzaburo; Shimojo, Naoki

    2015-01-01

    Allergies are characterized by a hypersensitive immune reaction to originally harmless antigens. In recent decades, the incidence of allergic diseases has markedly increased, especially in developed countries. The increase in the frequency of allergic diseases is thought to be primarily due to environmental changes related to a westernized lifestyle, which affects the commensal microbes in the human body. The human gut is the largest organ colonized by bacteria and contains more than 1000 bacterial species, called the "gut microbiota." The recent development of sequencing technology has enabled researchers to genetically investigate and clarify the diversity of all species of commensal microbes. The collective genomes of commensal microbes are together called the "microbiome." Although the detailed mechanisms remain unclear, it has been proposed that the microbiota/microbiome, especially that in the gut, impacts the systemic immunity and metabolism, thus affecting the development of various immunological diseases, including allergies. In this review, we summarize the recent findings regarding the importance of the microbiome/microbiota in the development of allergic diseases and also the results of interventional studies using probiotics or prebiotics to prevent allergies.

  18. Dark cities? Developing a methodology for researching dark tourism in European cities

    OpenAIRE

    Kennell, James; Powell, Raymond

    2016-01-01

    Despite the recent growth of research into dark tourism (Dale & Robinson, 2011; Lennon & Foley, 2000; Stone, 2013; Tarlow, 2005) and the growth of the dark tourism market (Biran & Hyde, 2013; Stone 2005; Stone & Sharpley, 2008), there has been little interest shown in understanding the relationship between dark tourism and urban tourism (Page & Hall 2002). This paper presents the initial findings of a research project that investigates the dark tourism products offered by European cities. A s...

  19. Seventh European Workshop on Cannabinoid Research and IACM Eighth Conference on Cannabinoids in Medicine

    OpenAIRE

    Cheer, Joseph F.; Maccarrone, Mauro; Piomelli, Daniele

    2016-01-01

    Abstract The joint 7th European Workshop on Cannabinoid Research and IACM 8th Conference on Cannabinoids in Medicine was held in the beach town of Sestri Levante, Italy, on September 17?19, 2015. In this beautiful setting, world-leading investigators in the field of (endo)cannabinoid research presented exciting new data spanning a broad array of preclinical and clinical topics?from cellular electrophysiology to drug discovery and from potential indications for the therapeutic use of cannabis ...

  20. Food allergies (image)

    Science.gov (United States)

    ... upon subsequent exposure to the substance. An actual food allergy, as opposed to simple intolerance due to the lack of digesting enzymes, is indicated by the production of antibodies to the food allergen, and by the release of histamines and ...

  1. Traveling with Food Allergies

    Science.gov (United States)

    ... on traveling and dining out at restaurants with food allergies. Travel Tips for the U.S. and Other Countries Get information about medications and food labeling practices in select countries. Spam Control Text: ...

  2. Allergies, asthma, and pollen

    Science.gov (United States)

    Reactive airway - pollen; Bronchial asthma - pollen; Triggers - pollen; Allergic rhinitis - pollen ... Things that make allergies or asthma worse are called triggers. It is important to know your triggers because avoiding them is your first step toward feeling better. ...

  3. Allergy and allergic diseases

    National Research Council Canada - National Science Library

    Kay, A. B

    2008-01-01

    ... and Other Tolerogenic Mechanisms in Allergy and Asthma, 83 Catherine Hawrylowicz and Cezmi A. Akdis 5 IgE and IgE Receptors, 103 Brian J. Sutton, Andrew J. Beavil, Rebecca L. Beavil and James Hunt...

  4. Contact allergy to lanolin

    DEFF Research Database (Denmark)

    Fransen, Marloes; Overgaard, Line E K; Johansen, Jeanne D

    2018-01-01

    BACKGROUND: Lanolin has been tested as lanolin alcohols (30% pet.) in baseline patch test series since 1969, and this has shown clinically relevant allergic contact dermatitis cases. OBJECTIVES: To investigate the temporal development of lanolin allergy (i.e. positive reaction to lanolin alcohols...... and/or Amerchol™ L-101), and the association between contact allergy to lanolin and patient characteristics from the MOAHLFA index. METHODS: A retrospective observational study of consecutively patch tested dermatitis patients (n = 9577) between 1 January 2004 and 31 December 2015 with lanolin...... alcohols 30% pet. and Amerchol™ L-101 50% pet. was performed. RESULTS: The prevalence of lanolin allergy increased from 0.45% in 2004 to 1.81% in 2015. In age-adjusted and sex-adjusted analyses, weak, significant associations were found between atopic dermatitis and lanolin and lanolin alcohols allergy...

  5. CONSIDERATIONS ON EUROPEAN POLICY OF RESEARCH, DEVELOPMENT, INNOVATION. CASE OF ROMANIA

    Directory of Open Access Journals (Sweden)

    Roxana Elena Lazăr

    2011-06-01

    Full Text Available The evolution of the European policy in the field of research, development, innovation reflects the maturity process of the European construction, through the very understanding of the particular role of knowledge in economy. An important aspect is the connection with the acknowledgment of the professional’s diplomas, which is based on the principle of automatism, on the mutual trust of the Member States in the qualifications obtained within the territory of any of them, on the tradition regarding the existence of a democratic and elitist education system. The improvement of the quality of education and the avoidance of sideslips are required. For the existence of a functional Euro-market in the field of research, development,innovation the differences between the European Union Member States have to be reduced, before attempting to catch up with the United States of America, Japan or China. Because knowledge is the inexhaustible resource of mankind in general, of the European Union, in particular, we should talk about a Union of Research, as we talk about the Monetary Union, for example. The strategy of economic growth in Romania was based on encouraging the consumers to spend money, but they didn’t consider a coherent policy based on innovations.

  6. A European multi-language initiative to make the general population aware of independent clinical research

    DEFF Research Database (Denmark)

    Mosconi, Paola; Antes, Gerd; Barbareschi, Giorgio

    2016-01-01

    2. An animated film about clinical trials, dubbed in the 23 official languages of the European Community, and an interactive tutorial 3. An inventory of resources, available in 23 languages, searchable by topic, author, and media type 4. Two educational games for young people, developed in six......BACKGROUND: The ECRAN (European Communication on Research Awareness Needs) project was initiated in 2012, with support from the European Commission, to improve public knowledge about the importance of independent, multinational, clinical trials in Europe. METHODS: Participants in the ECRAN...... materials and tools, making them freely available under a Creative Commons licence. RESULTS: The principal communication materials developed were: 1. A website ( http://ecranproject.eu ) in six languages, including a Media centre section to help journalists to disseminate information about the ECRAN project...

  7. Penicillin and beta-lactam allergy: epidemiology and diagnosis.

    Science.gov (United States)

    Macy, Eric

    2014-11-01

    Penicillin is the most common beta-lactam antibiotic allergy and the most common drug class allergy, reported in about 8% of individuals using health care in the USA. Only about 1% of individuals using health care in the USA have a cephalosporin allergy noted in their medical record, and other specific non-penicillin, non-cephalosporin beta-lactam allergies are even rarer. Most reported penicillin allergy is not associated with clinically significant IgE-mediated reactions after penicillin rechallenge. Un-verified penicillin allergy is a significant and growing public health problem. Clinically significant IgE-mediated penicillin allergy can be safely confirmed or refuted using skin testing with penicilloyl-poly-lysine and native penicillin G and, if skin test is negative, an oral amoxicillin challenge. Acute tolerance of an oral therapeutic dose of a penicillin class antibiotic is the current gold standard test for a lack of clinically significant IgE-mediated penicillin allergy. Cephalosporins and other non-penicillin beta-lactams are widely, safely, and appropriately used in individuals, even with confirmed penicillin allergy. There is little, if any, clinically significant immunologic cross-reactivity between penicillins and other beta-lactams. Routine cephalosporin skin testing should be restricted to research settings. It is rarely needed clinically to safely manage patients and has unclear predictive value at this time. The use of alternative cephalosporins, with different side chains, is acceptable in the setting of a specific cephalosporin allergy. Carbapenems and monobactams are also safely used in individuals with confirmed penicillin allergy. A certain predictable, but low, rate of adverse reactions will occur with all beta-lactam antibiotic use both pre- and post-beta-lactam allergy evaluations.

  8. The establishment of a network of European human research tissue banks.

    Science.gov (United States)

    Orr, Samantha; Alexandre, Eliane; Clark, Brain; Combes, Robert; Fels, Lueder M; Gray, Neil; Jönsson-Rylander, Ann-Cathrine; Helin, Heikki; Koistinen, Jukka; Oinonen, Teija; Richert, Lysiane; Ravid, Rivka; Salonen, Jarmo; Teesalu, Tambet; Thasler, Wolfgang; Trafford, Jacki; Van Der Valk, Jan; Von Versen, Rudiger; Weiss, Thomas; Womack, Chris; Ylikomi, Timo

    2002-01-01

    This is a report of a workshop held on the establishment of human research tissue banking which was held in Levi, Finland 21-24 March 2002. There were 21 participants from 7 European countries. This meeting was attended by representatives from academia, research tissue banks and from the Biotech and Pharmaceutical Industries. The principal aim of the workshop was to find a way to progress the recommendations from ECVAM workshop 44 (ATLA 29, 125-134, 2001) and ECVAM workshop 32 (ATLA 26, 763-777, 1998). The workshop represented the first unofficial meeting of the European Network of Research Tissue Banks (ENRTB) steering group. It is expected that in the period preceding the next workshop the ENRTB steering group will co-ordinate the ethical, legislative and organisational aspects of research tissue banking. Key issues dealt with by the Levi workshop included the practical aspects of sharing expertise and experiences across the different European members. Such collaboration between research tissue banks and end users of such material seeks to ultimately enable shared access to human tissue for medical and pharmaco-toxicological research while maintaining strict adherence to differences in legal and ethical aspects related to the use of human tissue in individual countries.

  9. Food Allergies: The Basics

    Science.gov (United States)

    Valenta, Rudolf; Hochwallner, Heidrun; Linhart, Birgit; Pahr, Sandra

    2015-01-01

    IgE-associated food allergy affects approximately 3% of the population and has severe effects on the daily life of patients—manifestations occur not only in the gastrointestinal tract but also affect other organ systems. Birth cohort studies have shown that allergic sensitization to food allergens develops early in childhood. Mechanisms of pathogenesis include cross-linking of mast cell– and basophil-bound IgE and immediate release of inflammatory mediators, as well as late-phase and chronic allergic inflammation, resulting from T-cell, basophil, and eosinophil activation. Researchers have begun to characterize the molecular features of food allergens and have developed chip-based assays for multiple allergens. These have provided information about cross-reactivity among different sources of food allergens, identified disease-causing food allergens, and helped us to estimate the severity and types of allergic reactions in patients. Importantly, learning about the structure of disease-causing food allergens has allowed researchers to engineer synthetic and recombinant vaccines. PMID:25680669

  10. Food allergies: the basics.

    Science.gov (United States)

    Valenta, Rudolf; Hochwallner, Heidrun; Linhart, Birgit; Pahr, Sandra

    2015-05-01

    IgE-associated food allergy affects approximately 3% of the population and has severe effects on the daily life of patients-manifestations occur not only in the gastrointestinal tract but also affect other organ systems. Birth cohort studies have shown that allergic sensitization to food allergens develops early in childhood. Mechanisms of pathogenesis include cross-linking of mast cell- and basophil-bound IgE and immediate release of inflammatory mediators, as well as late-phase and chronic allergic inflammation, resulting from T-cell, basophil, and eosinophil activation. Researchers have begun to characterize the molecular features of food allergens and have developed chip-based assays for multiple allergens. These have provided information about cross-reactivity among different sources of food allergens, identified disease-causing food allergens, and helped us to estimate the severity and types of allergic reactions in patients. Importantly, learning about the structure of disease-causing food allergens has allowed researchers to engineer synthetic and recombinant vaccines. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

  11. Fragrance contact allergy

    DEFF Research Database (Denmark)

    Johansen, Jeanne D

    2003-01-01

    . This gives a positive patch-test reaction in about 10% of tested patients with eczema, and the most recent estimates show that 1.7-4.1% of the general population are sensitized to ingredients of the fragrance mix. Fragrance allergy occurs predominantly in women with facial or hand eczema. These women...... development to identify contact allergy to new allergens, reflecting the continuous developments and trends in exposure....

  12. Changing Configurations of Adult Education in Transitional Times. Conference Proceedings of the Triennial European Research Conference of the European Society for Research on the Education of Adults (ESREA) (7th, Berlin, Germany, September 4-7, 2013)

    Science.gov (United States)

    Käpplinger, Bernd, Ed.; Lichte, Nina, Ed.; Haberzeth, Erik, Ed.; Kulmus, Claudia, Ed.

    2014-01-01

    This book assembles over 50 papers from the 7th Triennial European Research Conference of the European Society for Research on the Education of Adults (ESREA), which was held from the 4th to the 7th of September 2013 at Humboldt-University in Berlin. The title of the conference was "Changing Configurations of Adult Education in Transitional…

  13. Lettuce contact allergy

    DEFF Research Database (Denmark)

    Paulsen, Evy; Andersen, Klaus E

    2016-01-01

    Lettuce (Lactuca sativa L.) and its varieties are important vegetable crops worldwide. They are also well-known, rarely reported, causes of contact allergy. As lettuce allergens and extracts are not commercially available, the allergy may be underdiagnosed. The aims of this article are to present...... person who is occupationally exposed to lettuce for longer periods, especially atopics, amateur gardeners, and persons keeping lettuce-eating pets, is potentially at risk of developing lettuce contact allergy.......Lettuce (Lactuca sativa L.) and its varieties are important vegetable crops worldwide. They are also well-known, rarely reported, causes of contact allergy. As lettuce allergens and extracts are not commercially available, the allergy may be underdiagnosed. The aims of this article are to present...... new data on lettuce contact allergy and review the literature. Lettuce is weakly allergenic, and occupational cases are mainly reported. Using aimed patch testing in Compositae-allergic patients, two recent Danish studies showed prevalence rates of positive lettuce reactions of 11% and 22...

  14. Fish and shellfish allergy.

    Science.gov (United States)

    Thalayasingam, Meera; Lee, Bee-Wah

    2015-01-01

    Fish and shellfish consumption has increased worldwide, and there are increasing reports of adverse reactions to fish and shellfish, with an approximate prevalence of 0.5-5%. Fish allergy often develops early in life, whilst shellfish allergy tends to develop later, from adolescence onwards. Little is known about the natural history of these allergies, but both are thought to be persistent. The clinical manifestations of shellfish allergy, in particular, may vary from local to life-threatening 'anaphylactic' reactions within an individual and between individuals. Parvalbumin and tropomyosin are the two major allergens, but several other allergens have been cloned and described. These allergens are highly heat and biochemically stable, and this may in part explain the persistence of these allergies. Diagnosis requires a thorough history, skin prick and in-vitro-specific IgE tests, and oral challenges may be needed for diagnostic confirmation. Strict avoidance of these allergens is the current standard of clinical care for allergic patients, and when indicated, an anaphylactic plan with an adrenaline auto-injector is prescribed. There are no published clinical trials evaluating specific oral immunotherapy for fish or shellfish allergy. © 2015 S. Karger AG, Basel.

  15. Allergy in severe asthma.

    Science.gov (United States)

    Del Giacco, S R; Bakirtas, A; Bel, E; Custovic, A; Diamant, Z; Hamelmann, E; Heffler, E; Kalayci, Ö; Saglani, S; Sergejeva, S; Seys, S; Simpson, A; Bjermer, L

    2017-02-01

    It is well recognized that atopic sensitization is an important risk factor for asthma, both in adults and in children. However, the role of allergy in severe asthma is still under debate. The term 'Severe Asthma' encompasses a highly heterogeneous group of patients who require treatment on steps 4-5 of GINA guidelines to prevent their asthma from becoming 'uncontrolled', or whose disease remains 'uncontrolled' despite this therapy. Epidemiological studies on emergency room visits and hospital admissions for asthma suggest the important role of allergy in asthma exacerbations. In addition, allergic asthma in childhood is often associated with severe asthma in adulthood. A strong association exists between asthma exacerbations and respiratory viral infections, and interaction between viruses and allergy further increases the risk of asthma exacerbations. Furthermore, fungal allergy has been shown to play an important role in severe asthma. Other contributing factors include smoking, pollution and work-related exposures. The 'Allergy and Asthma Severity' EAACI Task Force examined the current evidence and produced this position document on the role of allergy in severe asthma. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases: report of the European Union Parliament Summit (29 March 2017).

    Science.gov (United States)

    Hellings, Peter W; Borrelli, David; Pietikainen, Sirpa; Agache, Ioana; Akdis, Cezmi; Bachert, Claus; Bewick, Michael; Botjes, Erna; Constantinidis, Jannis; Fokkens, Wytske; Haahtela, Tari; Hopkins, Claire; Illario, Maddalena; Joos, Guy; Lund, Valerie; Muraro, Antonella; Pugin, Benoit; Seys, Sven; Somekh, David; Stjärne, Pär; Valiulis, Arunas; Valovirta, Erkka; Bousquet, Jean

    2017-01-01

    On March 29, 2017, a European Summit on the Prevention and Self-Management of Chronic Respiratory Diseases (CRD) was organized by the European Forum for Research and Education in Allergy and Airway Diseases. The event took place in the European Parliament of Brussels and was hosted by MEP David Borrelli and MEP Sirpa Pietikainen. The aim of the Summit was to correspond to the needs of the European Commission and of patients suffering from CRD to join forces in Europe for the prevention and self-management. Delegates of the European Rhinologic Society, European Respiratory Society, European Academy of Allergy and Clinical Immunology, European Academy of Paediatrics, and European Patients Organization EFA all lectured on their vision and action plan to join forces in achieving adequate prevention and self-management of CRD in the context of Precision Medicine. Recent data highlight the preventive capacity of education on optimal care pathways for CRD. Self-management and patient empowerment can be achieved by novel educational on-line materials and by novel mobile health tools enabling patients and doctors to monitor and optimally treat CRDs based on the level of control. This report summarizes the contributions of the representatives of different European academic stakeholders in the field of CRD.

  17. Public health research in the UK: a report with a European perspective.

    Science.gov (United States)

    McCarthy, Mark; Dyakova, Mariana; Clarke, Aileen

    2014-06-01

    Public health research is of growing interest within Europe. Bibliometric research shows the UK with a high absolute output of public health publications, although lower per capita than Nordic countries. UK contributed to a European Union (EU) project PHIRE to assess public health research and innovation. UK health research structures, and programmes funded in 2010, were determined from internet search. Expert informants were asked to comment on national uptake of eight projects EU collaborative health projects. The Faculty of Public Health and the UK Society for Social Medicine discussed the findings at a meeting with stakeholders. Health research in UK is funded by research councils, the National Health Service (NHS) and independent foundations. Reviews and reports on public health research have encouraged diversified funding. There were 15 programmes and calls in 2010. The UK participated in all eight EU projects, and there was uptake of results for four. Strategic coordination between public health researchers and practitioners, and the UK research councils, ministries of health and medical charities would strengthen research for policy and practice. With growing expertise and capacity across other EU countries, the UK should take more active leadership in European collaboration. © The Author 2013, Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved.

  18. TRANSAUTOPHAGY: European network for multidisciplinary research and translation of autophagy knowledge

    Science.gov (United States)

    Casas, Caty; Codogno, Patrice; Pinti, Marcello; Batoko, Henri; Morán, María; Proikas-Cezanne, Tassula; Reggiori, Fulvio; Sirko, Agnieszka; Soengas, María S; Velasco, Guillermo; Lafont, Frank; Lane, Jon; Faure, Mathias; Cossarizza, Andrea

    2016-01-01

    abstract A collaborative consortium, named “TRANSAUTOPHAGY,” has been created among European research groups, comprising more than 150 scientists from 21 countries studying diverse branches of basic and translational autophagy. The consortium was approved in the framework of the Horizon 2020 Program in November 2015 as a COST Action of the European Union (COST means: CO-operation in Science and Technology), and will be sponsored for 4 years. TRANSAUTOPHAGY will form an interdisciplinary platform for basic and translational researchers, enterprises and stakeholders of diverse disciplines (including nanotechnology, bioinformatics, physics, chemistry, biology and various medical disciplines). TRANSAUTOPHAGY will establish 5 different thematic working groups, formulated to cooperate in research projects, share ideas, and results through workshops, meetings and short term exchanges of personnel (among other initiatives). TRANSAUTOPHAGY aims to generate breakthrough multidisciplinary knowledge about autophagy regulation, and to boost translation of this knowledge into biomedical and biotechnological applications. PMID:27046256

  19. TRANSAUTOPHAGY: European network for multidisciplinary research and translation of autophagy knowledge.

    Science.gov (United States)

    Casas, Caty; Codogno, Patrice; Pinti, Marcello; Batoko, Henri; Morán, María; Proikas-Cezanne, Tassula; Reggiori, Fulvio; Sirko, Agnieszka; Soengas, María S; Velasco, Guillermo; Lafont, Frank; Lane, Jon; Faure, Mathias; Cossarizza, Andrea

    2016-01-01

    A collaborative consortium, named "TRANSAUTOPHAGY," has been created among European research groups, comprising more than 150 scientists from 21 countries studying diverse branches of basic and translational autophagy. The consortium was approved in the framework of the Horizon 2020 Program in November 2015 as a COST Action of the European Union (COST means: CO-operation in Science and Technology), and will be sponsored for 4 years. TRANSAUTOPHAGY will form an interdisciplinary platform for basic and translational researchers, enterprises and stakeholders of diverse disciplines (including nanotechnology, bioinformatics, physics, chemistry, biology and various medical disciplines). TRANSAUTOPHAGY will establish 5 different thematic working groups, formulated to cooperate in research projects, share ideas, and results through workshops, meetings and short term exchanges of personnel (among other initiatives). TRANSAUTOPHAGY aims to generate breakthrough multidisciplinary knowledge about autophagy regulation, and to boost translation of this knowledge into biomedical and biotechnological applications.

  20. IgE-mediated allergy to chlorhexidine

    DEFF Research Database (Denmark)

    Garvey, Lene Heise; Krøigaard, Mogens; Poulsen, Lars K.

    2007-01-01

    Investigations at the Danish Anesthesia Allergy Centre have included testing for allergy to chlorhexidine since 1999.......Investigations at the Danish Anesthesia Allergy Centre have included testing for allergy to chlorhexidine since 1999....

  1. Allergen immunotherapy for insect venom allergy : protocol for a systematic review

    NARCIS (Netherlands)

    Dhami, Sangeeta; Nurmatov, Ulugbek; Varga, Eva-Maria; Sturm, Gunter; Muraro, Antonella; Akdis, Cezmi A.; Antolin-Amerigo, Dario; Bilo, M. Beatrice; Bokanovic, Danijela; Calderon, Moises A.; Cichocka-Jarosz, Ewa; Oude Elberink, Joanna N. G.; Gawlik, Radoslaw; Jakob, Thilo; Kosnik, Mitja; Lange, Joanna; Mingomataj, Ervin; Mitsias, Dimitris I.; Mosbech, Holger; Pfaar, Oliver; Pitsios, Constantinos; Pravettoni, Valerio; Roberts, Graham; Rueeff, Franziska; Sin, Betul Ayse; Sheikh, Aziz

    2016-01-01

    Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the

  2. Allergen immunotherapy for insect venom allergy : A systematic review and meta-analysis

    NARCIS (Netherlands)

    Dhami, S.; Zaman, H.; Varga, Eva-Maria; Sturm, G. J.; Muraro, A.; Akdis, C. A.; Antolin-Amerigo, D.; Bilo, M. B.; Bokanovic, Danijela; Calderon, M. A.; Cichocka-Jarosz, E.; Elberink, J. N. G. Oude; Gawlik, R.; Jakob, T.; Kosnik, M; Lange, J; Mingomataj, Ervin; Mitsias, Dimitris I.; Mosbech, H; Ollert, Markus; Pfaar, O.; Pitsios, Constantinos; Pravettoni, V.; Roberts, G.; Rueff, F.; Sin, Betul Ayse; Asaria, M.; Netuveli, G.; Sheikh, A.

    Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines on Allergen Immunotherapy (AIT) for the management of insect venom allergy. To inform this process, we sought to assess the effectiveness, cost-effectiveness and safety of

  3. Current policy and research on radioactive waste management in the European Union

    International Nuclear Information System (INIS)

    Forsstroem, H.; Taylor, D.M.

    2000-01-01

    Each Member State of the European Union is responsible for the safe management and disposal of the radioactive waste produced on its own territory. This includes setting the policy and taking the necessary steps to ensure that the radioactive waste does not constitute a threat to the health of workers and to the general public. For the practical implementation of the policy, specific waste management organizations have been established. Extensive cooperation, not least in the area of research, is taking place between these organizations and between the regulatory authorities, both bilaterally and through the European Commission. Cooperation takes place through the European Commission by two different mechanisms, the Community Plan of Action in the field of radioactive waste and the EURATOM framework programme on research and training. In view of the future enlargement of the European Union, the Commission is also actively involved in the development of waste management practices in the Central and Eastern European countries. Waste management is also an important aspect of the Tacis and other nuclear safety support programmes to the States of the former Soviet Union. The general policies for waste management in all Member States are in harmony with the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management. The specific policies are, however, dependent on the specific conditions of that State, e.g. the existence, size and time perspective of the nuclear power programme, the geological formations available for disposal (clay, salt, crystalline rock), etc. The management of short lived waste is an established practice in many Member States and the research needs are consequently low. Most of the policy efforts and research are thus dedicated to the management, treatment, conditioning and geological disposal of long lived waste and spent fuel. Each Member State with a nuclear power programme also has an important

  4. The European radioecology alliance: encouraging the coordination and integration of research activities in radioecology

    Energy Technology Data Exchange (ETDEWEB)

    Real, A. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas - CIEMAT (Spain); European Radioecology Alliance Association, French Institute for Radiological Protection and Nuclear Safety - IRSN, 31 Avenue de la Division Leclerc, BP 17, 92262 Fontenay-aux-Roses Cedex (France); Currivan, Lorraine [Radiological Protection Institute of Ireland - RPII (Ireland); Gariel, Jean-Christophe [Institut de Radioprotection et de Surete Nucleaire - IRSN (France); Hardeman, Frank [SCK.CEN (Belgium); Howard, Brenda [Natural Environment Research Council - NERC, UK (United Kingdom); Lukashenko, Sergey [Kazakhstan Republic Institute of Nuclear Physics - NNCRK (Kazakhstan); Lund, Ingemar [Swedish Radiation Safety Authority - SSM (Sweden); Sabatier, Laure [Commissariat a l' energie atomique et aux energies alternatives - CEA (France); Sachs, Susanne [Helmholtz-Zentrum Dresden-Rossendorf - HZDR (Germany); Salomaa, Sisko [Radiation and Nuclear Safety Authority - STUK (Finland); Smith, James [University of Portsmouth - UoP (United Kingdom); Steiner, Martin [Federal Office for Radiation Protection - BfS (Germany); Strand, Per [Norwegian Radiation Protection Authority - NRPA (Norway); Tschiersch, Jochen [Helmholtz Zentrum Muenchen - HMGU (Germany); Hinton, Thomas [Strategy for Allied Radioecology - STAR Coordinator, IRSN (France); Vandenhove, Hildegarde [COordination and iMplementation of a pan-European instrumenT for radioecology - COMET Coordinator, SCK.CEN (Belgium)

    2014-07-01

    The European Radioecology Alliance was established in 2009 with a firm conviction from its eight founding European organizations that joining forces would enhance the competence of radioecology science in Europe. The main objective of the Radioecology Alliance is to progressively strengthen the coordination and integration of research in the field of radioecology at national, European and international level. The integration of the European radioecology community will be a key aspect facing the upcoming EURATOM Horizon 2020 framework programme. In 2012, the Radioecology Alliance was officially constituted as an Association, and in June 2013 grew from 8 to 14 members from 10 different countries (Belgium, Finland, France, Germany, Ireland, Kazakhstan, Norway, Spain, Sweden and United Kingdom). Within the framework of the Radioecology Alliance, a Network of Excellence in Radioecology STAR (Strategy for Allied Radioecology) was created in 2011 with financial support of the EC FP7. More recently, the project COMET (Coordination and implementation of a pan-European instrument for radioecology) has been also funded by the EC to strengthen the pan-European research initiative on the radiation impact on man and the environment by facilitating the integration of the Research and Development activities in radioecology. The Radioecology Alliance, in close collaboration with STAR in the first phase, and more recently with COMET, has developed for the first time a Strategic Research Agenda (SRA) on Radioecology. The SRA identifies three challenges: (1) To predict human and wildlife exposure more robustly by quantifying the key processes that most influence radionuclide transfers; (2) To determine ecological consequences under realistic exposure conditions and (3) To improve human and environmental protection by integrating radioecology. Within these 3 challenges, 15 research lines have been identified. After a consultation process which included not only the scientific community

  5. Challenges for EURATOM research and training in the frame of the European 'Higher Education' And 'Research' areas

    International Nuclear Information System (INIS)

    Goethem, G. Van

    2009-01-01

    The paper is intended to answer two major questions of the modern society: 1) What are the challenges for EURATOM Research and Training in the frame of the European 'Higher Education' and 'Research' areas? (main stakeholders); 2) What kind of response is offered by the EURATOM RD and DD and E and T programmes in nuclear fission and radiation protection? (scientific and societal impact). The actions of the research policy in the EU are not conducted for the sake of acquiring Knowledge as a goal per se, but as a support to other EU policies, in particular, the Energy policy. In the area of fission and radiation protection, this Community policy implies the co-operation of all stakeholders (most of them participate in the EURATOM programmes), that is: research organisations (public and private, power and medical applications, etc); systems suppliers (e.g. nuclear vendors, engineering companies, etc); energy providers (e.g. electric utilities, heat and/or hydrogen vendors, etc); nuclear regulatory bodies and associated technical safety organizations (TSO); education and training (E and T) institutions, and, in particular, universities; civil society and the international institutional framework (IAEA and OECD/NEA). The emphasis in the paper is on the improvements all along the history of nuclear fission power (Generations I, II and III) as well as on the visionary innovation proposed by the 'Generation IV International Forum' (GIF). International research (in particular, EURATOM), in this area is guided by the four 'GIF Technology Goals for industry and society', namely: sustainability: e.g. enhanced fuel utilisation and optimal waste management; economics: e.g. minimisation of costs of MWe installed and MWh generated; safety and reliability: e.g. robust safety architecture, no need for off-site measures; proliferation resistance and physical protection: e.g. absence of separated Pu. EURATOM research and training is presented in the broader context of the new EU policy

  6. Allergoids for allergy treatment.

    Science.gov (United States)

    Carnes, Jeronimo; Gallego, Maria T; Moya, Raquel; Iraola, Victor

    2018-02-21

    Background Chemically modified allergen extracts, known as allergoids, are commonly used for treating allergic patients. In general terms, the concept of allergoids implies allergen extracts with a reduction of their allergenicity maintaining their immunogenicity. Different methods to obtain allergoids have been developed in the past years, opening attractive lines of research. Objective To review the different approaches to allergoid development as well as their characterization, mechanism of action and efficacy and safety issues. Methods A revision and analysis of the different types of allergoids has been performed, with special attention to patents submitted and granted in the last years. Additionally, updated information about the mechanism of action and clinical evidence and safety of allergoids has been discussed. Results Principally, allergoids are obtained by the polymerization of native allergen extracts with aldehydes, including formaldehyde or glutaraldehyde. However, recent patents and publications about different chemical modifications have been presented, as well as about the use of new adjuvants with allergoids. Regarding the characterization, allergoids require more sophisticated analytical methods than native extracts, as a consequence of their properties and characteristics. Conclusion In the last years, the partial understanding of the mechanism of action and the generation of clinical evidence of different types of allergoids, linked to their excellent safety profile and their convenience for a quick build up phase, have made of allergoids an excellent product for allergy treatment. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  7. Sesame allergy: current perspectives

    Directory of Open Access Journals (Sweden)

    Adatia A

    2017-04-01

    Full Text Available Adil Adatia,1 Ann Elaine Clarke,2 Yarden Yanishevsky,3 Moshe Ben-Shoshan4 1Department of Medicine, University of Alberta, Edmonton, 2Division of Rheumatology, Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, 3Section of Allergy and Clinical Immunology, Department of Pediatrics, University of Alberta, Edmonton, AB, 4Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, Montreal Children’s Hospital, McGill University Health Centre, Montreal, QC, Canada Abstract: Sesame is an important global allergen affecting ~0.1% of the North American population. It is a major cause of anaphylaxis in the Middle East and is the third most common food allergen in Israel. We conducted a systematic review of original articles published in the last 10 years regarding the diagnosis and management of sesame allergy. Skin prick testing appears to be a useful predictor of sesame allergy in infants, although data are less consistent in older children and adults. The diagnostic capacity of serum-specific immunoglobulin E is poor, especially in studies that used oral food challenges to confirm the diagnosis. Double-blind, placebo-controlled food challenge thus remains the diagnostic gold standard for sesame allergy. The cornerstone of sesame allergy management is allergen avoidance, though accidental exposures are common and patients must be prepared to treat the consequent reactions with epinephrine. Novel diagnostic and treatment options such as component-resolved diagnostics, basophil activation testing, and oral immunotherapy are under development but are not ready for mainstream clinical application. Keywords: sesame allergy, skin prick testing, specific IgE, component-resolved diagnostics, epinephrine autoinjector

  8. Common definition for categories of clinical research: a prerequisite for a survey on regulatory requirements by the European Clinical Research Infrastructures Network (ECRIN)

    DEFF Research Database (Denmark)

    Kubiak, Christine; de Andres-Trelles, Fernando; Kuchinke, Wolfgang

    2009-01-01

    in relation to the wide spectrum of clinical research, the European Clinical Research Infrastructures Network (ECRIN) developed a multinational survey in ten European countries. However a lack of common classification framework for major categories of clinical research was identified, and therefore reaching...... with cell therapy, etc.); diagnostic studies; clinical research on nutrition; other interventional clinical research (including trials in complementary and alternative medicine, trials with collection of blood or tissue samples, physiology studies, etc.); and epidemiology studies. Our classification...

  9. Innovations in Doctoral Training and Research on Tinnitus: The European School on Interdisciplinary Tinnitus Research (ESIT Perspective

    Directory of Open Access Journals (Sweden)

    Winfried Schlee

    2018-01-01

    Full Text Available Tinnitus is a common medical condition which interfaces many different disciplines, yet it is not a priority for any individual discipline. A change in its scientific understanding and clinical management requires a shift toward multidisciplinary cooperation, not only in research but also in training. The European School for Interdisciplinary Tinnitus research (ESIT brings together a unique multidisciplinary consortium of clinical practitioners, academic researchers, commercial partners, patient organizations, and public health experts to conduct innovative research and train the next generation of tinnitus researchers. ESIT supports fundamental science and clinical research projects in order to: (1 advancing new treatment solutions for tinnitus, (2 improving existing treatment paradigms, (3 developing innovative research methods, (4 performing genetic studies on, (5 collecting epidemiological data to create new knowledge about prevalence and risk factors, (6 establishing a pan-European data resource. All research projects involve inter-sectoral partnerships through practical training, quite unlike anything that can be offered by any single university alone. Likewise, the postgraduate training curriculum fosters a deep knowledge about tinnitus whilst nurturing transferable competencies in personal qualities and approaches needed to be an effective researcher, knowledge of the standards, requirements and professionalism to do research, and skills to work with others and to ensure the wider impact of research. ESIT is the seed for future generations of creative, entrepreneurial, and innovative researchers, trained to master the upcoming challenges in the tinnitus field, to implement sustained changes in prevention and clinical management of tinnitus, and to shape doctoral education in tinnitus for the future.

  10. For the Anniversary Edition of the Scientific Journal European Researcher. Series A – 110 issue

    Directory of Open Access Journals (Sweden)

    Goran Rajović

    2016-09-01

    Full Text Available This article is a review of the jubilee scientific journal "European Researcher. Series A ", marked at all in 2016 – the sixth anniversary, of regular and of continuous publication. In addition to the history of the newspaper are exposed to the development phase of its program concept. The journal is the period 2010 – 2016 year, profiled in an important factor of development and the formation of professional and scientific thought. Journal “European Research. Series A” is now open forum for publicizing and stimulating innovative thinking on all aspects of the social sciences, the entire international academic community. In all this we emphasize the infinite persistence, creative energy but also authoring and management merits chief editor and founder of the Journal, DrAleksandrCherkasov for survival and development for this great publishing project.

  11. European neonatal intensive care nursing research priorities: an e-Delphi study.

    Science.gov (United States)

    Wielenga, Joke M; Tume, Lyvonne N; Latour, Jos M; van den Hoogen, Agnes

    2015-01-01

    This study aimed to identify and prioritise neonatal intensive care nursing research topics across Europe using an e-Delphi technique. An e-Delphi technique with three questionnaire rounds was performed. Qualitative responses of round one were analysed by content analysis and research statements were generated to be ranged on importance on a scale of 1-6 (not important to most important). Neonatal intensive care units (NICUs) in 17 European countries. NICU clinical nurses, managers, educators and researchers (n=75). None. A list of 43 research statements in eight domains. The six highest ranking statements (≥5.0 mean score) were related to prevention and reduction of pain (mean 5.49; SD 1.07), medication errors (mean 5.20; SD 1.13), end-of-life care (mean 5.05; SD 1.18), needs of parents and family (mean 5.04; SD 1.23), implementing evidence into nursing practice (mean 5.02; SD 1.03), and pain assessment (mean 5.02; SD 1.11). The research domains were prioritised and ranked: (1) pain and stress; (2) family centred care; (3) clinical nursing care practices; (4) quality and safety; (5) ethics; (6) respiratory and ventilation; (7) infection and inflammation; and (8) professional issues in neonatal intensive care nursing. The results of this study might support developing a nursing research strategy for the nursing section of the European Society of Paediatric and Neonatal Intensive Care. In addition, this may promote more European researcher collaboratives for neonatal nursing research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  12. NFFA-Europe: enhancing European competitiveness in nanoscience research and innovation (Conference Presentation)

    Science.gov (United States)

    Carsughi, Flavio; Fonseca, Luis

    2017-06-01

    NFFA-EUROPE is an European open access resource for experimental and theoretical nanoscience and sets out a platform to carry out comprehensive projects for multidisciplinary research at the nanoscale extending from synthesis to nanocharacterization to theory and numerical simulation. Advanced infrastructures specialized on growth, nano-lithography, nano-characterization, theory and simulation and fine-analysis with Synchrotron, FEL and Neutron radiation sources are integrated in a multi-site combination to develop frontier research on methods for reproducible nanoscience research and to enable European and international researchers from diverse disciplines to carry out advanced proposals impacting science and innovation. NFFA-EUROPE will enable coordinated access to infrastructures on different aspects of nanoscience research that is not currently available at single specialized ones and without duplicating their specific scopes. Approved user projects will have access to the best suited instruments and support competences for performing the research, including access to analytical large scale facilities, theory and simulation and high-performance computing facilities. Access is offered free of charge to European users and users will receive a financial contribution for their travel, accommodation and subsistence costs. The users access will include several "installations" and will be coordinated through a single entry point portal that will activate an advanced user-infrastructure dialogue to build up a personalized access programme with an increasing return on science and innovation production. The own research activity of NFFA-EUROPE will address key bottlenecks of nanoscience research: nanostructure traceability, protocol reproducibility, in-operando nano-manipulation and analysis, open data.

  13. 77 FR 2736 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-19

    ... Infectious Diseases Special Emphasis Panel; NIAID Clinical Trial Planning and Implementation. Date: February..., Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and Infectious Diseases Research...

  14. 77 FR 74676 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-17

    ... Allergy and Infectious Diseases Special Emphasis Panel; NIAID Clinical Trial Planning and Implementation... Transplantation Research; 93.856, Microbiology and Infectious Diseases Research, National Institutes of Health...

  15. 77 FR 20645 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Science.gov (United States)

    2012-04-05

    ... Diseases Special Emphasis Panel; NIAID Clinical Trial Implementation Cooperative Agreements. Date: May 1..., Allergy, Immunology, and Transplantation Research; 93.856, Microbiology and Infectious Diseases Research...

  16. 76 FR 32980 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings

    Science.gov (United States)

    2011-06-07

    ... Allergy and Infectious Diseases Special Emphasis Panel; Clinical Trial Implementation Grants. Date: June... Research; 93.856, Microbiology and Infectious Diseases Research, National Institutes of Health, HHS) Dated...

  17. Obstacles to European research projects with data and tissue: solutions and further challenges.

    Science.gov (United States)

    van Veen, Evert-Ben

    2008-07-01

    Most European biomedical research projects are about data. Research with tissue is about data as well; data will accompany the tissue, and data will be derived from analysing the tissue. Data can be merged with data from various sources, copied and re-analysed in the context of European projects. Privacy enhancing technologies (PET) should be used for transferring data from participating centres to the level where data are being merged. PET provide coding techniques which allow donors to be anonymous and still uniquely discernable. It is defended that under certain conditions two-way coded data can be considered as anonymous data in the sense of the European Data Protection Directive. Divergent interpretations of this Directive and most of all about the concept of coded-anonymous data is one of the main obstacles to observational research in Europe. The Data Protection Authorities will have to relax the extremely high threshold before data cannot be considered personal data anymore. Arguments are given for such relaxation. Besides the logic and logistics of data transfer in European projects, it is also about trust and a realistic risk assessment. In spite of the massive dataflow in European research projects no breach of confidentiality has ever been reported. The ethical rationale of such projects can be based on the principles of citizenship and solidarity provided that certain safeguards are met by which that research will remain observational. However, if the project does not preclude individual feed-back on the outcomes of research, as in theory would be possible with two-way coded tissue, that tissue cannot be considered anonymous. It is argued that in most tissuebanking projects individual feed-back should be excluded. Tissuebanking for research should not turn into medical screening without applying the established criteria for screening to it. If individual feed-back is not foreseen, two-way tissue should be considered anonymous, under the same conditions

  18. Excessive nickel release from mobile phones--a persistent cause of nickel allergy and dermatitis

    DEFF Research Database (Denmark)

    Jensen, Peter; Johansen, Jeanne D; Zachariae, Claus

    2011-01-01

    Despite the political intention to limit nickel allergy and dermatitis in Europeans, nickel allergy remains frequent. There are several explanations for the persistence of nickel allergy and dermatitis, including the increasing use of mobile phones. Before regulation of nickel release from mobile...... phones, we showed that eight (19.5%) of 41 mobile phones marketed in Denmark between 2003 and 2007 released nickel in concentrations that may result in nickel allergy and dermatitis. In 2009, the EU Nickel Directive was revised to include nickel-releasing mobile phones....

  19. Excessive nickel release from mobile phones--a persistent cause of nickel allergy and dermatitis

    DEFF Research Database (Denmark)

    Jensen, Peter; Johansen, Jeanne D; Zachariae, Claus

    2011-01-01

    phones, we showed that eight (19.5%) of 41 mobile phones marketed in Denmark between 2003 and 2007 released nickel in concentrations that may result in nickel allergy and dermatitis. In 2009, the EU Nickel Directive was revised to include nickel-releasing mobile phones.......Despite the political intention to limit nickel allergy and dermatitis in Europeans, nickel allergy remains frequent. There are several explanations for the persistence of nickel allergy and dermatitis, including the increasing use of mobile phones. Before regulation of nickel release from mobile...

  20. Oral allergy syndrome to chicory associated with birch pollen allergy

    NARCIS (Netherlands)

    Cadot, P.; Kochuyt, A.-M.; van Ree, R.; Ceuppens, J. L.

    2003-01-01

    BACKGROUND: A few cases of IgE-mediated chicory allergy with oral, cutaneous, and/or respiratory symptoms are reported. We present 4 patients with inhalant birch pollen allergy and oral allergy syndrome to chicory. IgE-binding proteins in chicory and cross-reactivity with birch pollen were studied.

  1. Accelerating science and innovation societal benefits of European research in Particle Physics

    CERN Multimedia

    Radford, Tim; Jakobsson, Camilla; Marsollier, Arnaud; Mexner, Vanessa; O'Connor, Terry

    2013-01-01

    The story so far. Collaborative research in particle physics. The lesson for Europe: co-operation pays. Medicine and life sciences. The body of knowledge: particles harnessed for health. Energy and the environment. Think big: save energy and clean up the planet. Communication and new technologies. The powerhouse of invention. Society and skills. Power to the people. The European Strategy for Particle Physics. Update 2013.

  2. Enterprises’ Growth Potential in the European Union: Implications for Research and Innovation Policy

    OpenAIRE

    MONCADA PATERNO' CASTELLO Pietro; CINCERA Michele

    2012-01-01

    One of the main objectives of the new European research and innovation policy agenda is to favour the positive demographics (creation and growth) of EU companies operating in new/knowledge-intensive industries, especially Small and Medium Enterprises (SMEs). These companies play an important role in shaping the dynamism of the economy’s sectoral composition, favouring the transition towards more knowledge-intensive activities and in contributing to the overall economic growth objectives and m...

  3. What Are the Main Drivers of Young Consumers Purchasing Traditional Food Products? European Field Research

    Science.gov (United States)

    Kyrgiakos, Leonidas

    2018-01-01

    In this research, the attitude of European young adults (age 18 to 30 years) regarding their consumption of local and traditional products was examined. The survey was conducted on a sample of 836 consumers from seven European countries (Greece, Bulgaria, Romania, Slovenia, Croatia, Denmark and France). Data collection was made by distributing a developed questionnaire through social media and university mail services. Principal Component Analysis (PCA) was used to identify consumer perception comparing the overall sample with two subsets (consumers from Eastern and Western European countries). Six major factors were revealed: consumer behavior, uncertainty about health issues, cost, influence of media and friends and availability in store. Young adults had a positive attitude to local and traditional food products, but they expressed insecurity about health issues. Cost factor had less of an influence on interviewees from Eastern European countries than those from the overall sample (3rd and 5th factor accordingly). Influence of close environment was a different factor in Eastern countries compared to Western ones, for which it was common to see an influence from media. Females and older people (25–30 years old) have fewer doubts about Traditional Food Products, while media have a high influence on consumers’ decisions. The aim of this survey was to identify the consumer profiles of young adults and create different promotion strategies of local and traditional products among the two groups of countries. PMID:29439536

  4. What Are the Main Drivers of Young Consumers Purchasing Traditional Food Products? European Field Research

    Directory of Open Access Journals (Sweden)

    George Vlontzos

    2018-02-01

    Full Text Available In this research, the attitude of European young adults (age 18 to 30 years regarding their consumption of local and traditional products was examined. The survey was conducted on a sample of 836 consumers from seven European countries (Greece, Bulgaria, Romania, Slovenia, Croatia, Denmark and France. Data collection was made by distributing a developed questionnaire through social media and university mail services. Principal Component Analysis (PCA was used to identify consumer perception comparing the overall sample with two subsets (consumers from Eastern and Western European countries. Six major factors were revealed: consumer behavior, uncertainty about health issues, cost, influence of media and friends and availability in store. Young adults had a positive attitude to local and traditional food products, but they expressed insecurity about health issues. Cost factor had less of an influence on interviewees from Eastern European countries than those from the overall sample (3rd and 5th factor accordingly. Influence of close environment was a different factor in Eastern countries compared to Western ones, for which it was common to see an influence from media. Females and older people (25–30 years old have fewer doubts about Traditional Food Products, while media have a high influence on consumers’ decisions. The aim of this survey was to identify the consumer profiles of young adults and create different promotion strategies of local and traditional products among the two groups of countries.

  5. The European fusion research and development programme and the ITER Project

    International Nuclear Information System (INIS)

    Green, B.J.

    2004-01-01

    The EURATOM fusion R and D programme is a well integrated and co-ordinated programme a good example of a European Research Area. Its goal is 'the joint creation of prototype reactors for power stations to meet the needs of society: operational safety, environmental compatibility, economic viability'. The programme is focussed on the magnetic confinement approach to fusion energy and supports 21 associated laboratories and a range of experimental and fusion technology facilities. The paper will briefly describe this programme and how it is organised and implemented. Its success and that of other national programmes has defined the international ITER Project, which is the next logical step in fusion R and D. The paper will describe ITER, its aims, its design, and the supporting manufacture of prototype components. The European contribution to ITER, as well as the exploitation of the Joint European Torus (JET) and long-term fusion reactor technology R and D are carried out under the European Fusion Development Agreement (EFDA). Finally, the potential advantages of fusion as an energy source will be presented. (author)

  6. Research infrastructures of pan-European interest: The EU and Global issues

    Energy Technology Data Exchange (ETDEWEB)

    Pero, Herve, E-mail: Herve.Pero@ec.europa.e [' Research Infrastructures' Unit, DG Research, European Commission, Brussels (Belgium)

    2011-01-21

    Research Infrastructures act as 'knowledge industries' for the society and as a source of attraction for world scientists. At European level, the long-term objective is to support an efficient and world-class eco-system of Research Infrastructures, encompassing not only the large single-site facilities but also distributed research infrastructures, based on a network of 'regional partner facilities', with strong links with world-class universities and centres of excellence. The EC support activities help to promote the development of this fabric of research infrastructures of the highest quality and performance in Europe. Since 2002 ESFRI is also aimed at supporting a coherent approach to policy-making on research infrastructures. The European Roadmap for Research Infrastructures is ESFRI's most significant achievement to date, and KM3Net is one of its identified projects. The current Community support to the Preparatory Phase of this project aims at solving mainly governance, financial, organisational and legal issues. How should KM3Net help contributing to an efficient Research Infrastructure eco-system? This is the question to which the KM3Net stakeholders need to be able to answer very soon!

  7. Research infrastructures of pan-European interest: The EU and Global issues

    International Nuclear Information System (INIS)

    Pero, Herve

    2011-01-01

    Research Infrastructures act as 'knowledge industries' for the society and as a source of attraction for world scientists. At European level, the long-term objective is to support an efficient and world-class eco-system of Research Infrastructures, encompassing not only the large single-site facilities but also distributed research infrastructures, based on a network of 'regional partner facilities', with strong links with world-class universities and centres of excellence. The EC support activities help to promote the development of this fabric of research infrastructures of the highest quality and performance in Europe. Since 2002 ESFRI is also aimed at supporting a coherent approach to policy-making on research infrastructures. The European Roadmap for Research Infrastructures is ESFRI's most significant achievement to date, and KM3Net is one of its identified projects. The current Community support to the Preparatory Phase of this project aims at solving mainly governance, financial, organisational and legal issues. How should KM3Net help contributing to an efficient Research Infrastructure eco-system? This is the question to which the KM3Net stakeholders need to be able to answer very soon!

  8. Research infrastructures of pan-European interest: The EU and Global issues

    Science.gov (United States)

    Pero, Hervé

    2011-01-01

    Research Infrastructures act as “knowledge industries” for the society and as a source of attraction for world scientists. At European level, the long-term objective is to support an efficient and world-class eco-system of Research Infrastructures, encompassing not only the large single-site facilities but also distributed research infrastructures, based on a network of “regional partner facilities”, with strong links with world-class universities and centres of excellence. The EC support activities help to promote the development of this fabric of research infrastructures of the highest quality and performance in Europe. Since 2002 ESFRI is also aimed at supporting a coherent approach to policy-making on research infrastructures. The European Roadmap for Research Infrastructures is ESFRI's most significant achievement to date, and KM3Net is one of its identified projects. The current Community support to the Preparatory Phase of this project aims at solving mainly governance, financial, organisational and legal issues. How should KM3Net help contributing to an efficient Research Infrastructure eco-system? This is the question to which the KM3Net stakeholders need to be able to answer very soon!

  9. A European Flood Database: facilitating comprehensive flood research beyond administrative boundaries

    Directory of Open Access Journals (Sweden)

    J. Hall

    2015-06-01

    Full Text Available The current work addresses one of the key building blocks towards an improved understanding of flood processes and associated changes in flood characteristics and regimes in Europe: the development of a comprehensive, extensive European flood database. The presented work results from ongoing cross-border research collaborations initiated with data collection and joint interpretation in mind. A detailed account of the current state, characteristics and spatial and temporal coverage of the European Flood Database, is presented. At this stage, the hydrological data collection is still growing and consists at this time of annual maximum and daily mean discharge series, from over 7000 hydrometric stations of various data series lengths. Moreover, the database currently comprises data from over 50 different data sources. The time series have been obtained from different national and regional data sources in a collaborative effort of a joint European flood research agreement based on the exchange of data, models and expertise, and from existing international data collections and open source websites. These ongoing efforts are contributing to advancing the understanding of regional flood processes beyond individual country boundaries and to a more coherent flood research in Europe.

  10. European Training and Research in Peritoneal Dialysis: scientific objectives, training, implementation and impact of the programme.

    Science.gov (United States)

    Foster, Tom L; Ferrantelli, Evelina; van Wier-van der Schaaf, Tanja; Beelen, Robert H J

    2014-03-01

    Peritoneal dialysis (PD) offers many advantages over hospital-based haemodialysis, including better quality of life. Despite this, there is a general under-utilisation of PD in Europe, which, to some extent, can be attributed to a lack of knowledge and education amongst renal clinicians and nurses. The specific aim of the European Training and Research in Peritoneal Dialysis (EuTRiPD) programme is to address this lack of knowledge, to develop a minimum of five biomarkers that allow the prediction of outcome in PD and three therapeutic treatments to improve outcome in PD. EuTRiPD is a EU-wide consortium with clinical, academic and commercial partners set up to address this knowledge gap. By training through research and close collaboration between academic and commercial entities we hope to improve the outcome and uptake of PD. It is the goal of EuTRiPD to improve the currently hampered diagnostic therapeutic developments in renal replacement therapy (RRT) and structure existing high-quality PD-related research across Europe. It is hoped that EuTRiPD can and will have a significant impact on socio-economic and scientific aspects of PD. It is the aim for EuTRiPD to boost the uptake of PD throughout Europe by making PD the obvious choice for patients. © 2013 European Dialysis and Transplant Nurses Association/European Renal Care Association.

  11. Allergy and orthodontics

    Science.gov (United States)

    Chakravarthi, Sunitha; Padmanabhan, Sridevi; Chitharanjan, Arun B.

    2012-01-01

    The aim of this paper is to review the current literature on allergy in orthodontics and to identify the predisposing factors and the implications of the allergic reaction in the management of patients during orthodontic treatment. A computerized literature search was conducted in PubMed for articles published on allergy in relation to orthodontics. The MeSH term used was allergy and orthodontics. Allergic response to alloys in orthodontics, particularly nickel, has been extensively studied and several case reports of nickel-induced contact dermatitis have been documented. Current evidence suggests that the most common allergic reaction reported in orthodontics is related to nickel in orthodontic appliances and allergic response is more common in women due to a previous sensitizing exposure from nickel in jewellery. Studies have implicated allergy in the etiology of hypo-dontia. It has also been considered as a high-risk factor for development of extensive root resorption during the course of orthodontic treatment. This review discusses the relationship and implications of allergy in orthodontics. PMID:24987632

  12. Lettuce contact allergy.

    Science.gov (United States)

    Paulsen, Evy; Andersen, Klaus E

    2016-02-01

    Lettuce (Lactuca sativa L.) and its varieties are important vegetable crops worldwide. They are also well-known, rarely reported, causes of contact allergy. As lettuce allergens and extracts are not commercially available, the allergy may be underdiagnosed. The aims of this article are to present new data on lettuce contact allergy and review the literature. Lettuce is weakly allergenic, and occupational cases are mainly reported. Using aimed patch testing in Compositae-allergic patients, two recent Danish studies showed prevalence rates of positive lettuce reactions of 11% and 22%. The majority of cases are non-occupational, and may partly be caused by cross-reactivity. The sesquiterpene lactone mix seems to be a poor screening agent for lettuce contact allergy, as the prevalence of positive reactions is significantly higher in non-occupationally sensitized patients. Because of the easy degradability of lettuce allergens, it is recommended to patch test with freshly cut lettuce stem and supplement this with Compositae mix. As contact urticaria and protein contact dermatitis may present as dermatitis, it is important to perform prick-to-prick tests, and possibly scratch patch tests as well. Any person who is occupationally exposed to lettuce for longer periods, especially atopics, amateur gardeners, and persons keeping lettuce-eating pets, is potentially at risk of developing lettuce contact allergy. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. Fish allergy: in review.

    Science.gov (United States)

    Sharp, Michael F; Lopata, Andreas L

    2014-06-01

    Globally, the rising consumption of fish and its derivatives, due to its nutritional value and divergence of international cuisines, has led to an increase in reports of adverse reactions to fish. Reactions to fish are not only mediated by the immune system causing allergies, but are often caused by various toxins and parasites including ciguatera and Anisakis. Allergic reactions to fish can be serious and life threatening and children usually do not outgrow this type of food allergy. The route of exposure is not only restricted to ingestion but include manual handling and inhalation of cooking vapors in the domestic and occupational environment. Prevalence rates of self-reported fish allergy range from 0.2 to 2.29 % in the general population, but can reach up to 8 % among fish processing workers. Fish allergy seems to vary with geographical eating habits, type of fish processing, and fish species exposure. The major fish allergen characterized is parvalbumin in addition to several less well-known allergens. This contemporary review discusses interesting and new findings in the area of fish allergy including demographics, novel allergens identified, immunological mechanisms of sensitization, and innovative approaches in diagnosing and managing this life-long disease.

  14. Pediatric allergy and immunology in Brazil.

    Science.gov (United States)

    Rosario-Filho, Nelson A; Jacob, Cristina M; Sole, Dirceu; Condino-Neto, Antonio; Arruda, Luisa K; Costa-Carvalho, Beatriz; Cocco, Renata R; Camelo-Nunes, Inês; Chong-Neto, Herberto J; Wandalsen, Gustavo F; Castro, Ana P M; Yang, Ariana C; Pastorino, Antonio C; Sarinho, Emanuel S

    2013-06-01

    The subspecialty of pediatric allergy and immunology in Brazil is in its early years and progressing steadily. This review highlights the research developed in the past years aiming to show the characteristics of allergic and immunologic diseases in this vast country. Epidemiologic studies demonstrated the high prevalence of asthma in infants, children, and adolescents. Mortality rates and average annual variation of asthma hospitalization have reduced in all pediatric age groups. Indoor aeroallergen exposure is excessively high and contributes to the high rates of allergy sensitization. Prevalence of food allergy has increased to epidemic levels. Foods (35%), insect stings (30%), and drugs (23%) are the main etiological agents of anaphylaxis in children and adolescents. Molecular diagnosis of primary immunodeficiencies (PID) showed a high incidence of fungal infections including paracoccidioidomycosis in X-linked hyper-IgM syndrome, and the occurrence of BCG adverse reactions or other mycobacterial infections in patients with chronic granulomatous disease. Education in pediatric allergy and immunology is deficient for medical students, but residency programs are effective in training internists and pediatricians for the practice of allergy. The field of PID requires further training. Last, this review is a tribute to Prof. Dr. Charles Naspitz, one of the pioneers of our specialty in Brazil. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

  15. Allergies in Germany -- prevalence and perception by the public.

    Science.gov (United States)

    Augustin, Matthias; Franzke, Nadine; Beikert, Florian C; Stadler, Rudolf; Reusch, Michael; Schmitt, Jochen; Schäfer, Ines

    2013-06-01

    During the recent decades allergies have become more frequent all over the world. However, it is unclear how important the topic of allergies is for the general German population and how appropriately patients with allergies are treated. A telephone survey was performed on a representative random sample of n = 1,004 adults in Germany. The survey was performed by the Forsa Institute for Social Research and Statistical Analysis, Berlin, Germany, in the period from 31 January to 2 February 2012. Of the interviewees 52% responded that the topic of allergies concerned them; in 33% actually an allergy had been diagnosed by a physician. The proportion of allergies in the population correlated with the level of school education and was higher among people with a higher educational status. No differences in allergy rates were found between Eastern and Western Germany. Among allergic persons, 53% reported to be burdened by their allergy, 48% suffered from impaired performance because of their allergic symptoms. Among people suffering from pollen allergy, only 28% received sublingual immune therapy, with which 70% were satisfied. While 58% practiced self-medication, only 21% of the allergic persons were treated with anti-allergic drugs during their allergy flares. Allergic diseases are a common, often burdensome problem in the German population, but nevertheless the medical treatment of people affected is still insufficient. The proportion of patients receiving sublingual immune therapy as causal treatment is comparatively low. Active steps are needed to improve the utilization behavior of patients, e. g. to take advice of an allergy specialist. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

  16. Research on prisoners - a comparison between the IOM Committee recommendations (2006) and European regulations.

    Science.gov (United States)

    Elger, Bernice S; Spaulding, Anne

    2010-01-01

    The Institute of Medicine (IOM) Committee on Ethical Considerations for Revisions to DHHS Regulations for Protection of Prisoners Involved in Research published its report in 2006. It was charged with developing an ethical framework for the conduct of research with prisoners and identifying the safeguards and conditions necessary to ensure that research with prisoners is conducted ethically. The recommendations contained in the IOM report differ from current European regulations in several ways, some being more restrictive and some less so. For example, the IOM report suggests limiting the percentage of prisoners that should be involved in a biomedical study to 50%, a limit that does not exist in Europe. However, the report does not specifically advise against research without a direct benefit to an individual prisoner: the European regulations are more restrictive than the IOM committee recommendations in this respect. The definition of minimal risk varies, as well as the proposed role of the minimal risk requirement and of the principle of subsidiarity (research that can only be done effectively in prisons). The IOM report proposes a number of thoughtful suggestions, which it would be beneficial to implement everywhere, such as registers of research on prisoners. The European regulations offer pragmatic solutions to several thorny issues. In summary, the IOM committee report represents an admirable effort to tackle the present inconsistencies and deficiencies of federal regulations in the US on research on prisoners (45 CFR 46 Subpart C). Nonetheless, before acting on the recommendations, US regulators might consider revisiting international guidelines such as those published by the Council for International Organizations of Medical Science (CIOMS) and the Declaration of Helsinki.

  17. Report of the Independent Expert Group on the Future of European Public Health Research

    DEFF Research Database (Denmark)

    Olsen, Jørn

    2013-01-01

    Directorate General has set up an independent expert group. Its task was to take stock of the impacts, challenges and limitations of EU-funded public health research under the current and previous research framework programmes, and to identify priorities for future research. The experts, who worked in two...... agendas and national policy agendas? How to improve the uptake of evidence generated from public health research in the development of public health policy? This report summarises the recommendations from Subgroup 2.......The next EU research and innovation framework programme 'Horizon 2020' will address a number of important societal challenges including health, demographic changes and well-being. To prepare the work in these areas, the Health Directorate of the European Commission's Research & Innovation...

  18. The European Research on Severe Accidents in Generation-II and -III Nuclear Power Plants

    Directory of Open Access Journals (Sweden)

    Jean-Pierre Van Dorsselaere

    2012-01-01

    Full Text Available Forty-three organisations from 22 countries network their capacities of research in SARNET (Severe Accident Research NETwork of excellence to resolve the most important remaining uncertainties and safety issues on severe accidents in existing and future water-cooled nuclear power plants (NPP. After a first project in the 6th Framework Programme (FP6 of the European Commission, the SARNET2 project, coordinated by IRSN, started in April 2009 for 4 years in the FP7 frame. After 2,5 years, some main outcomes of joint research (modelling and experiments by the network members on the highest priority issues are presented: in-vessel degraded core coolability, molten-corium-concrete-interaction, containment phenomena (water spray, hydrogen combustion…, source term issues (mainly iodine behaviour. The ASTEC integral computer code, jointly developed by IRSN and GRS to predict the NPP SA behaviour, capitalizes in terms of models the knowledge produced in the network: a few validation results are presented. For dissemination of knowledge, an educational 1-week course was organized for young researchers or students in January 2011, and a two-day course is planned mid-2012 for senior staff. Mobility of young researchers or students between the European partners is being promoted. The ERMSAR conference is becoming the major worldwide conference on SA research.

  19. Pediatric allergy and immunology in Japan.

    Science.gov (United States)

    Ebisawa, Motohiro; Nishima, Sankei; Ohnishi, Hidenori; Kondo, Naomi

    2013-11-01

    The Japanese Society of Pediatric Allergy and Clinical Immunology (JSPACI) was started in 1966 and currently has 3613 members as of August 1, 2012. The number of pediatricians specializing in allergies who have been certified by the Japanese Society of Allergology is 817. Among these, there are 125 training directors and training facilities for allergy and clinical immunology. The JSPACI first published an asthma guideline specific for children in 2000, and this has been revised every 3 yrs, contributing to better control of pediatric asthma. Food allergy management guidelines were first developed in 2005, which have helped to improve the care of food allergy patients. Among 514 pediatric training programs by the Japanese Society of Pediatrics, there are 312 facilities routinely performing oral food challenges. Among these, there were already 53 facilities performing oral immunotherapy at the end of 2011, treating 1400 cases of food allergy. The prevalence of pediatric allergic diseases has increased in Japan over the past 50 yrs. A number of International Study of Asthma and Allergies in Childhood surveys have been conducted in the past at specific times. The prevalence of wheezing among children aged 13-14 yrs in 2002 was 13.0%. Multi-year surveys found a 1.5- to 2-fold increase every 10 yrs until 2002. However, according to the latest data in 2012, asthma prevalence seems to have slightly decreased in Japan. Food allergy mainly associated with infantile atopic eczema among infants younger than 1 yr of age is the most common form as with other developed countries. The estimated food allergy prevalence based on data from several surveys is 5-10% among infants (0-6 yrs) and 1-2% among schoolchildren (6-15 yrs). A variety of patients suffering from primary deficiency syndrome have been actively analyzed. Previously, antibody defects and well-defined syndromes with immunodeficiency were analyzed, but recent research is focusing on not only acquired immune

  20. The European Community's research and development programme on the decommissioning of nuclear installations

    International Nuclear Information System (INIS)

    Skupinski, E.

    1988-01-01

    The Commission of the European Communities (CEC) continued with a second research programme on the decommissioning of nuclear installations (1984-88), after having completed a first programme on the decommissioning of nuclear power plants (1979-83). The programme, which has about 70 research contracts with organisations or private firms in the member states, includes the development and testing of advanced techniques, such as decontamination and dismantling, and the consideration of the radioactive waste arising therefrom. Work is done at laboratory scale or in the context of large-scale decommissioning operations. The paper will give an overview on the technical content and on some selected results. (author)

  1. European Community research on improving the governance of nuclear waste management and other risks

    International Nuclear Information System (INIS)

    Forsstroem, H.; Kelly, N.

    2002-01-01

    Increasing attention is being given to broader socio-economic issues (eg, science and society, governance of risk, etc) within the European Commission's research programmes. This reflects the recognition of the importance of such issues for science policy and decision making with respect to nuclear and other technologies. This paper summarises those projects, supported by the Commission's Euratom research programme, which focus on socio-economic as opposed to narrower technical issues. These projects are concerned with risk governance in general, the governance of nuclear waste management and stakeholder involvement in the off-site management of accidents. (author)

  2. European legislation impedes critical care research and fails to protect patients' rights

    DEFF Research Database (Denmark)

    Berg, Ronan M G; Møller, Kirsten; Rossel, Peter Johannes Hancke

    2011-01-01

    in which a waiver of consent is deemed necessary, the Ethical Review Board should ensure that non-therapeutic risks are minimal, that the research is specifically designed to benefit critically ill patients, and that it cannot be conducted under circumstances where an informed consent can be obtained....... If the European Directive is changed accordingly, this permits clinical trials in critical care settings, while adequate protection from risky non-therapeutic procedures is ensured and exploitation of the patient as an easily accessible research subject is prevented....

  3. Observations and actions to ensure equal treatment of all candidates by the European Research Council

    Science.gov (United States)

    Rydin, Claudia Alves de Jesus; Farina Busto, Luis; El Mjiyad, Nadia; Kota, Jhansi; Thelen, Lionel

    2017-04-01

    The European Research Council (ERC), Europe's premiere funding agency for frontier research, views equality of opportunities as an important challenge. The ERC monitors closely gender figures on every call and has taken actions to tackle imbalances and potential unconscious biases. The ERC talk is focused on efforts made to understand and ensure equal treatment of all candidates, with particular focus on gender balance and with specific attention to geosciences. Data and statistics collected in running highly competitive and internationally recognised funding schemes are presented. Recent initiatives to tackle geographical imbalances will also be presented.

  4. Strategies for the implementation of a European Volcano Observations Research Infrastructure

    Science.gov (United States)

    Puglisi, Giuseppe

    2015-04-01

    Active volcanic areas in Europe constitute a direct threat to millions of people on both the continent and adjacent islands. Furthermore, eruptions of "European" volcanoes in overseas territories, such as in the West Indies, an in the Indian and Pacific oceans, can have a much broader impacts, outside Europe. Volcano Observatories (VO), which undertake volcano monitoring under governmental mandate and Volcanological Research Institutions (VRI; such as university departments, laboratories, etc.) manage networks on European volcanoes consisting of thousands of stations or sites where volcanological parameters are either continuously or periodically measured. These sites are equipped with instruments for geophysical (seismic, geodetic, gravimetric, electromagnetic), geochemical (volcanic plumes, fumaroles, groundwater, rivers, soils), environmental observations (e.g. meteorological and air quality parameters), including prototype deployment. VOs and VRIs also operate laboratories for sample analysis (rocks, gases, isotopes, etc.), near-real time analysis of space-borne data (SAR, thermal imagery, SO2 and ash), as well as high-performance computing centres; all providing high-quality information on the current status of European volcanoes and the geodynamic background of the surrounding areas. This large and high-quality deployment of monitoring systems, focused on a specific geophysical target (volcanoes), together with the wide volcanological phenomena of European volcanoes (which cover all the known volcano types) represent a unique opportunity to fundamentally improve the knowledge base of volcano behaviour. The existing arrangement of national infrastructures (i.e. VO and VRI) appears to be too fragmented to be considered as a unique distributed infrastructure. Therefore, the main effort planned in the framework of the EPOS-PP proposal is focused on the creation of services aimed at providing an improved and more efficient access to the volcanological facilities

  5. Overview and status of the Next European Dipole Joint Research Activity

    International Nuclear Information System (INIS)

    Devred, A; Baudouy, B; Baynham, D E

    2006-01-01

    The Next European Dipole (NED) Joint Research Activity was launched on 1 January 2004 to promote the development of high-performance Nb 3 Sn conductors in collaboration with European industry (aiming at a non-copper critical current density of 1500 A mm -2 at 4.2 K and 15 T) and to assess the suitability of Nb 3 Sn technology to the next generation of accelerator magnets (aiming at an aperture of 88 mm and a conductor peak field of ∼15 T). It is part of the Coordinated Accelerator Research in Europe (CARE) project, which involves eight collaborators, and is half-funded by the European Union. After briefly recalling the Activity organization, we report the main progress achieved over the last year, which includes: the manufacturing of a double-bath He II cryostat for heat transfer measurements through Nb 3 Sn conductor insulation, detailed quench computations for various NED-like magnet configurations, the award of two industrial subcontracts for Nb 3 Sn conductor development, the first results of a cross-calibration programme of test facilities for Nb 3 Sn wire characterization, detailed investigations of the mechanical properties of heavily cold-drawn Cu/Nb/Sn composite wires, and the preliminary assessment of a new insulation system based on polyimide-sized glass fibre tapes. Last, we briefly review the efforts of an ongoing Working Group on magnet design and optimization

  6. Overview and status of the Next European Dipole (NED) joint research activity

    CERN Document Server

    Devred, Arnaud; Baynham, D Elwyn; Boutboul, T; Canfer, S; Chorowski, M; Fabbricatore, P; Farinon, S; Félice, H; Fessia, P; Fydrych, J; Granata, V; Greco, Michela; Greenhalgh, J; Leroy, D; Loveridge, P W; Matkowski, M; Michalski, G; Michel, F; Oberli, L R; den Ouden, A; Pedrini, D; Pietrowicz, S; Polinski, J; Previtali, V; Quettier, L; Richter, D; Rifflet, J M; Rochford, J; Rondeaux, F; Sanz, S; Scheuerlein, C; Schwerg, N; Sgobba, Stefano; Sorbi, M; Toral-Fernandez, F; Van Weelderen, R; Védrine, P; Volpini, G

    2006-01-01

    The Next European Dipole (NED) Joint Research Activity was launched on 1st January 2004 to promote the development of high performance Nb$_{3}$Sn conductors in collaboration with European industry (aiming at a non-copper critical current density of 1500 A/mm2 at 4.2 K and 15 T) and to assess the suitability of Nb$_{3}$Sn technology to the next generation of accelerator magnets (aiming at an aperture of 88 mm and a conductor peak field of ~ 15 T). It is part of the Coordinated Accelerator Research in Europe (CARE) project, involves eight collaborators and is half-funded by the European Union. After briefly recalling the Activity organization, we report the main progress achieved over the last year, which includes: the manufacturing of a double-bath He II cryostat for heat transfer measurements through Nb$_{3}$Sn conductor insulation, detailed quench computations for various NED-like magnet configurations, the award of two industrial subcontracts for Nb$_{3}$Sn conductor development, the first results of a cros...

  7. Boron Neutron Capture Therapy at European research reactors - Status and perspectives

    International Nuclear Information System (INIS)

    Moss, R.L.

    2004-01-01

    Over the last decade. there has been a significant revival in the development of Boron Neutron Capture Therapy (BNCT) as a treatment modality for curing cancerous tumours, especially glioblastoma multiforme and subcutaneous malignant melanoma. In 1987 a European Collaboration on BNCT was formed, with the prime task to identify suitable research reactors in Europe where BNCT could be applied. Due to reasons discussed in this paper, the HFR Petten was chosen as the test-bed for demonstrating BNCT. Currently, the European Collaboration is approaching the start of clinical trials, using epithermal neutrons and borocaptate sodium (BSH) as the 10 B delivery agent. The treatment is planned to start in the first half of 1996. The paper here presents an overview on the principle of BNCT, the requirements imposed on a research reactor in order to be considered for BNCT, and the perspectives for other European materials testing reactors. A brief summary on the current status of the work at Petten is given, including: the design, construction and characterisation of the epithermal neutron beam: performance and results of the healthy tissue tolerance study; the development of a treatment planning programme based on the Monte Carlo code MCNP; the design of an irradiation room; and on the clinical trials themselves. (author)

  8. Deciphering the black box of food allergy mechanisms.

    Science.gov (United States)

    Sampath, Vanitha; Tupa, Dana; Graham, Michelle Toft; Chatila, Talal A; Spergel, Jonathan M; Nadeau, Kari C

    2017-01-01

    To review our current understanding of immunotherapy, the immune mechanisms underlying food allergy, and the methodological advances that are furthering our understanding of the role of immune cells and other molecules in mediating food allergies. Literature searches were performed using the following combination of terms: allergy, immunotherapy, food, and mechanisms. Data from randomized clinical studies using state-of-the-art mechanistic tools were prioritized. Articles were selected based on their relevance to food allergy. Current standard of care for food allergies is avoidance of allergenic foods and the use of epinephrine in case of severe reaction during unintentional ingestion. During the last few decades, great strides have been made in understanding the cellular and molecular mechanisms underlying food allergy, and this information is spearheading the development of exciting new treatments. Immunotherapy protocols are effective in desensitizing individuals to specific allergens; however, recurrence of allergic sensitization is common after discontinuation of therapy. Interestingly, in a subset of individuals, immunotherapy is protective against allergens even after discontinuation of immunotherapy. Whether this protection is permanent is currently unknown because of inadequate long-term follow-up data. Research on understanding the underlying mechanisms may assist in modifying protocols to improve outcome and enable sustained unresponsiveness, rather than a temporary relief against food allergies. The cellular changes brought about by immunotherapy are still a black box, but major strides in our understanding are being made at an exciting pace. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  9. Indoor and Outdoor Allergies.

    Science.gov (United States)

    Singh, Madhavi; Hays, Amy

    2016-09-01

    In last 30 to 40 years there has been a significant increase in the incidence of allergy. This increase cannot be explained by genetic factors alone. Increasing air pollution and its interaction with biological allergens along with changing lifestyles are contributing factors. Dust mites, molds, and animal allergens contribute to most of the sensitization in the indoor setting. Tree and grass pollens are the leading allergens in the outdoor setting. Worsening air pollution and increasing particulate matter worsen allergy symptoms and associated morbidity. Cross-sensitization of allergens is common. Treatment involves avoidance of allergens, modifying lifestyle, medical treatment, and immunotherapy. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Sustainable Bridges – A European Integrated Research Project – Background Overview and Results

    DEFF Research Database (Denmark)

    Täljsten, Björn; Elfgren, Lennart

    2008-01-01

    of energy and release of greenhouse gases. To help our society to be more sustainable, it is important to retain and use what we already have where possible, rather than investing in new structures. Instead of tearing down old, often beautiful, railway bridges and replacing them with new ones, we need...... to preserve and upgrade them by using better assessment, monitoring and strengthening methods. This was also the aim of the European Integrated Research Project “Sustainable Bridges – Assessment for Future Traffic Demands and Longer Lives” when it was accepted for funding by the European Commission in 2003....... The project established the following three specific goals: 1. increase the transport capacity of existing railway bridges by allowing higher axle loads (up to 33 tons) for freight traffic at moderate speeds or by allowing higher speeds (up to 350 km/hour) for passenger traffic with low axle loads 2. extend...

  11. Responsible decision-making for plant research and breeding innovations in the European Union

    DEFF Research Database (Denmark)

    Eriksson, Ulf Dennis; Chatzopoulou, Sevasti

    2017-01-01

    Plant research and breeding has made substantial technical progress over the past few decades, indicating a potential for tremendous societal impact. Due to this potential, the development of policies and legislation on plant breeding and the technical progress should preferably involve all...... relevant stakeholders. However, we argue here that there is a substantial imbalance in the European Union (EU) regarding the influence of the various stakeholder groups on policy makers. We use evidence from three examples in order to show that the role of science is overlooked: 1) important delays...... in the decision process concerning the authorization of genetically modified (GM) maize events, 2) the significance attributed to non-scientific reasons in new legislation concerning the prohibition of GM events in EU member states, and 3) failure of the European Commission to deliver legal guidance to new plant...

  12. Poverty-Related Diseases College: a virtual African-European network to build research capacity.

    Science.gov (United States)

    Dorlo, Thomas P C; Fernández, Carmen; Troye-Blomberg, Marita; de Vries, Peter J; Boraschi, Diana; Mbacham, Wilfred F

    2016-01-01

    The Poverty-Related Diseases College was a virtual African-European college and network that connected young African and European biomedical scientists working on poverty-related diseases. The aim of the Poverty-Related Diseases College was to build sustainable scientific capacity and international networks in poverty-related biomedical research in the context of the development of Africa. The Poverty-Related Diseases College consisted of three elective and mandatory training modules followed by a reality check in Africa and a science exchange in either Europe or the USA. In this analysis paper, we present our experience and evaluation, discuss the strengths and encountered weaknesses of the programme, and provide recommendations to policymakers and funders.

  13. First Tuesday@CERN: Industrial partnership and innovation management at European research laboratories

    CERN Multimedia

    2003-01-01

    On Wednesday 19 March, CERN will host for the second time the 'First Tuesday Geneva' events for entrepreneurs, investors and all those interested in new technologies. The event is organised by the non-profit group Rezonance. The theme of this "First Tuesday@CERN" is familiar to CERN, as it concerns new trends of industrial partnership and innovation management at European research laboratories. As major sources of innovative technologies, large laboratories such as CERN, ESA, EMBL or ESRF have adopted over the past few years new strategies in the areas of industrial partnership and technological spin-offs. Speakers include: - Pierre Brisson, Head of Technology Transfer and Promotion Office, ESA : "The European Space Incubator at ESA" - Gabor Lamm, Managing Director EMBL Enterprise Management Technology Transfer : "EMBL Enterprise Management: Innovation Works" - Edward Mitchell, Coordinator of the PSB, ESRF : "The Partnership for Structural Biology" - Wolfgang von Rüden, Leader of Information Tech...

  14. PERL - European research project on characterization of gaskets for bolted flange connections

    International Nuclear Information System (INIS)

    Kockelmann, H.; Hahn, R.

    2004-01-01

    Great progress was observed in the European standardization in the last years in the field of the design of floating type bolted flange connections. New design rules were developed (EN 1591) which include new definitions of gasket characteristics for the calculation of floating type flanged joints. In addition a new gasket testing standard was drafted (prEN 13555) which assures a comprehensive characterization of gaskets for bolted flanged joints. This draft standard contains some new features which were examined and validated within the European research project PERL (Pressure Equipment - Reduction of Leak Rate). The gasket testing strategy laid down in prEN 13555 is presented in this paper. Some testing results highlighten the measuring procedures and the evaluation of the gasket characteristics. (orig.)

  15. Building a strong European alliance for personality disorder research and intervention.

    Science.gov (United States)

    Mehlum, Lars; Bateman, Anthony; Dalewijk, Henk Jan; Doering, Stephan; Kaera, Andres; Moran, Paul Anthony; Renneberg, Babette; Ribaudi, Joaquim Soler; Simonsen, Sebastian; Wilberg, Theresa; Bohus, Martin

    2018-01-01

    People with personality disorders frequently face stigma, ignorance and pessimism regarding the treatability of their disorders. This is despite substantial progress that has been made in developing a number of effective evidence based psychotherapeutic treatments. However, expertise in how to systematically deliver these treatments in a sustainable way throughout Europe is largely lacking. To bridge the gap between evidence based treatments and their implementation in health services, the European Society for the Study of Personality Disorders is currently building a new alliance of experts to promote personality disorder scholarship, and to support the development of clinical expertise and systematic treatment implementation throughout Europe. The aim of this paper is to describe how the Society is currently using its interdisciplinary and international roster of experts to address the specific treatment and research needs of the European personality disorder field, particularly to countries in which expertise in the field is less developed.

  16. Allergies and suicidal behaviors: a systematic literature review.

    Science.gov (United States)

    Kõlves, Kairi; Barker, Emma; De Leo, Diego

    2015-01-01

    Allergies are among the most common chronic conditions. In addition to physical and social impacts, a number of studies have consistently linked allergies to poor psychological outcomes, including depression and anxiety. The aim of the present systematic literature review was to analyze the existing literature about the relationship between allergies and fatal and nonfatal suicidal behaviors. Data sources include articles retrieved from Scopus, PubMed, ProQuest, and Web of Knowledge. Search terms: "suicid* and (allerg* or hay fever or atop* or eczema or aeroallergen*)" in English-language peer-reviewed journals between 1990 and 2014. Original research articles that provide empiric evidence about the potential link between allergies and suicidal behaviors. The initial search identified a total of 769 articles with 17 original research articles that present empiric evidence. Nine articles analyzed the relationship between allergies and fatal suicidal behavior, and nine analyzed nonfatal suicidal behaviors (one article included both). There currently is little research into the relationship between allergies and suicidal behavior. The review was restricted to English-language articles published within the chosen time period; other limitations included the small number of articles that involve suicide mortality, and the fact that the majority of articles originated from the United States and Scandinavia. Analysis of the results indicates a link between allergies and suicidality, particularly suicide mortality; however, results for nonfatal suicidal behaviors are mixed. It is important that further research by using more rigorous study designs be carried out to lend strength to these findings.

  17. What Principals Should Know About Food Allergies.

    Science.gov (United States)

    Munoz-Furlong, Anne

    2002-01-01

    Describes what principals should know about recent research findings on food allergies (peanuts, tree nuts, milk, eggs, soy, wheat) that can produce severe or life-threatening reactions in children. Asserts that every school should have trained staff and written procedures for reacting quickly to allergic reactions. (PKP)

  18. Historical European Martial Art a crossroad between academic research, martial heritage re-creation and martial sport practices

    Directory of Open Access Journals (Sweden)

    Jaquet Daniel

    2015-05-01

    Full Text Available Historical European martial arts (HEMA have to be considered an important part of our common European cultural heritage. Studies within this field of research have the potential to enlighten the puzzle posed by past societies, for example in the field of history, history of science and technology, or fields related to material culture.

  19. Indicators of prescribing quality in drug utilisation research : report of a European meeting (DURQUIM, 13-15 May 2004)

    NARCIS (Netherlands)

    Hoven, JL; Haaijer-Ruskamp, FM; Vander Stichele, RH

    An invitational expert meeting on indicators of prescribing quality was held on 13-15 May 2004, bringing together-from 19 European countries, the US, Canada, and Australia-40 researchers specialized in the development and application of indicators. The meeting was organized by the European Drug

  20. The power of science economic research and European decision-making : the case of energy and environment policies

    CERN Document Server

    Rossetti di Valdalbero, Domenico

    2010-01-01

    This book highlights the interaction between science and politics and between research in economics and European Union policy-making. It focuses on the use of Quantitative tools, Top-down and Bottom-up models in up-stream European decision-making process through five EU policy case studies: energy taxation, climate change, energy efficiency, renewable energy, and internalisation of external costs.