WorldWideScience

Sample records for eub decision 2006-112

  1. Guide 61: how the EUB responds to utility customer service complaints

    International Nuclear Information System (INIS)

    1999-07-01

    The guide answers common questions about regulated provincial utilities, how to make a formal complaint to the Electric Utilities Board (EUB) of Alberta about utility service, and how the Board handles customer concerns. The role of the EUB in regulating utilities has changed slightly with natural gas deregulation, with most consumers having the option to purchase natural gas from their supplier of choice. As the transition to electric deregulation is occuring, the EUB continues to set customer rates until the transition is complete. When a utility-related-complaint cannot be resolved, the EUB may schedule a hearing to thoroughly review the issue. The hearing and decision aspects are summarized

  2. Lattice strain accompanying the colossal magnetoresistance effect in EuB6.

    Science.gov (United States)

    Manna, Rudra Sekhar; Das, Pintu; de Souza, Mariano; Schnelle, Frank; Lang, Michael; Müller, Jens; von Molnár, Stephan; Fisk, Zachary

    2014-08-08

    The coupling of magnetic and electronic degrees of freedom to the crystal lattice in the ferromagnetic semimetal EuB(6), which exhibits a complex ferromagnetic order and a colossal magnetoresistance effect, is studied by high-resolution thermal expansion and magnetostriction experiments. EuB(6) may be viewed as a model system, where pure magnetism-tuned transport and the response of the crystal lattice can be studied in a comparatively simple environment, i.e., not influenced by strong crystal-electric field effects and Jahn-Teller distortions. We find a very large lattice response, quantified by (i) the magnetic Grüneisen parameter, (ii) the spontaneous strain when entering the ferromagnetic region, and (iii) the magnetostriction in the paramagnetic temperature regime. Our analysis reveals that a significant part of the lattice effects originates in the magnetically driven delocalization of charge carriers, consistent with the scenario of percolating magnetic polarons. A strong effect of the formation and dynamics of local magnetic clusters on the lattice parameters is suggested to be a general feature of colossal magnetoresistance materials.

  3. EUB Decision 2007-061 : West Energy Ltd., applications for well licences, Pembina Field

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-08-08

    West Energy Ltd. applied to the Alberta Energy and Utilities Board for licences to drill two level-2 sour crude oil wells to obtain crude oil from the Nisku Formation, about 3 km east of the Hamlet of Rocky Rapids, Alberta. Both wells are expected to contain 160 moles per kilomole hydrogen sulfide (H{sub 2}S). The expected cumulative H{sub 2}S release rate for the drilling and completion phases of the wells is 2.5 m{sup 3}/s, while for suspended and producing phases it is 0.44 m{sup 3}/s. Objections were received from 124 intervening parties who expressed concerns regarding health and safety, flaring, air quality, proliferation, emergency response planning, contamination of land and animals, and compensation. A public hearing was held in March 2007 to hear the views of the Board, the interested parties and the interveners. The Board considered various issues, including communication and participant involvement; need and timing of the wells; location of the wells; safety; human and livestock health; property values; and, environmental impacts. Having reviewed the evidence, the Board granted conditional approval for West Energy Ltd. to drill 2 sour crude oil wells near Rocky Rapids. The EUB imposed 10 conditions on West Energy Ltd. that will address public concerns raised during the 11-day hearing. With the conditions, the Board considers these wells to represent a low level of risk when failure probability, mitigating measures and enhanced emergency response plans are taken into account. 2 tabs., 1 fig., 4 appendices.

  4. EUB Decision 2007-061 : West Energy Ltd., applications for well licences, Pembina Field

    International Nuclear Information System (INIS)

    2007-01-01

    West Energy Ltd. applied to the Alberta Energy and Utilities Board for licences to drill two level-2 sour crude oil wells to obtain crude oil from the Nisku Formation, about 3 km east of the Hamlet of Rocky Rapids, Alberta. Both wells are expected to contain 160 moles per kilomole hydrogen sulfide (H 2 S). The expected cumulative H 2 S release rate for the drilling and completion phases of the wells is 2.5 m 3 /s, while for suspended and producing phases it is 0.44 m 3 /s. Objections were received from 124 intervening parties who expressed concerns regarding health and safety, flaring, air quality, proliferation, emergency response planning, contamination of land and animals, and compensation. A public hearing was held in March 2007 to hear the views of the Board, the interested parties and the interveners. The Board considered various issues, including communication and participant involvement; need and timing of the wells; location of the wells; safety; human and livestock health; property values; and, environmental impacts. Having reviewed the evidence, the Board granted conditional approval for West Energy Ltd. to drill 2 sour crude oil wells near Rocky Rapids. The EUB imposed 10 conditions on West Energy Ltd. that will address public concerns raised during the 11-day hearing. With the conditions, the Board considers these wells to represent a low level of risk when failure probability, mitigating measures and enhanced emergency response plans are taken into account. 2 tabs., 1 fig., 4 appendices

  5. Electronic and magnetic phase separation in EuB6. Fluctuation spectroscopy and nonlinear transport

    International Nuclear Information System (INIS)

    Amyan, Adham

    2013-01-01

    The main topics of this thesis are electrical, stationary, and time-resolved transport measurements on EuB 6 as well as the further development of measuring methods and analysis procedures of the fluctuation spectroscopy. The first part of this thesis was dedicated to the further development of the already known measuring methods under application of a fast data-acquisition card. The second part deals with the electrical transport properties of EuB 6 and the understanding of the coupling between charge and magnetic degrees of freedom. By means of resistance and nonlinear-transport measurements as well as fluctuation spectroscopy hypotheses of other scientists were systematically verified as well as new knowledge obtained. The magnetoresistance was studied as function of the temperature in small external magnetic fields between 1 mT and 700 mT. Measurements of the third harmonic resistance as function of the temperature show maxima at T MI and T C . Electrical-resistance fluctuations were measured without external magnetic field between 5 and 100 K as well in presence of a magnetic field between 18 K and 32 K. At constant temperature measurements of the spectral power density in external magnetic fields were performed in the temperature range from 18 K to 32 K. Highly resolving measurements of the thermal expansion coefficient showed a very strong coupling of the magnetic (polaronic) degrees of freedom to the crystal lattice.

  6. Adoption of the 2006 Field Triage Decision Scheme for Injured Patients

    Directory of Open Access Journals (Sweden)

    Sasser, Scott

    2011-07-01

    Full Text Available Background: When emergency medical services (EMS providers respond to the scene of an injury, they must decide where to transport the injured patients for further evaluation and treatment. This is done through a process known as “field triage”, whereby a patient’s injuries are matched to the most appropriate hospital. In 2005-2006 the National Expert Panel on Field Triage, convened by the Centers for Disease Control and Prevention and the National Highway Traffic Safety Administration, revised the 1999 American College of Surgeons Committee on Trauma Field Triage Decision Scheme. This revision, the 2006 Field Triage Decision Scheme, was published in 2006.Methods: State Public Health departments’ and EMS’ external websites were evaluated to ascertain the current status of implementation of the 2006 Field Triage Decision Scheme.Results: Information regarding field triage was located for 41 states. In nine states no information regarding field triage was available on their websites. Of the 41 states where information was located, seven were classified as “full adopters” of the 2006 Field Triage Decision Scheme; nine were considered “partial adopters”; 17 states were found to be using a full version or modification of the 1999 Field Triage Decision Scheme; and eight states were considered to be using a different protocol or scheme for field triage.Conclusion: Many states have adopted the 2006 Decision Scheme (full or partial. Further investigation is needed to determine the reasons why some states do not adopt the guidelines. [West J Emerg Med. 2011;12(3:275-283.

  7. 32 CFR 865.112 - Decisional issues.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Decisional issues. 865.112 Section 865.112...-GENERAL PERSONNEL REVIEW BOARDS Air Force Discharge Review Board § 865.112 Decisional issues. (a) The decisional document shall discuss the issues that provide a basis for the decision whether there should be a...

  8. 77 FR 20485 - Notice of Receipt of Petition for Decision That Nonconforming 1999 to 2006 Toyota Land Cruiser...

    Science.gov (United States)

    2012-04-04

    ...-0035, Notice 1] Notice of Receipt of Petition for Decision That Nonconforming 1999 to 2006 Toyota Land... Administration (NHTSA) of a petition for a decision that nonconforming 1999 to 2006 Toyota Land Cruiser IFS 100... manufacturer as complying with the safety standards (the U.S.-certified version of the 1999 to 2006 Toyota Land...

  9. Federal Government response to the September 12, 2000 environmental assessment report of the EUB-CEAA Joint Review Panel on the Cheviot Coal Project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-04-01

    The Federal Court noted four deficiencies in the joint EUB-CEAA environmental review dated September 12, 2000 for the Cheviot Coal Project. The Joint Review Panel reconvened to hear additional evidence about these deficiencies. This memorandum to cabinet comprises the Government of Canada's response to the additional evidence. Some of the Panel's recommendations are accepted. Comments are included regarding migratory birds, protection of traditional aboriginal sites, economic benefits, grizzly bears, and fish habitat.

  10. Working Memory Load and Decision Making: A Reply to Franco-Watkins, Pashler, and Rickard (2006)

    Science.gov (United States)

    Hinson, John M.; Whitney, Paul

    2006-01-01

    A. M. Franco-Watkins, H. Pashler, and T. C. Rickard (2006) discussed some interesting issues about the interpretation of working memory load effects and decision making in their reanalysis of our previously published data (J. M. Hinson, T. L. Jameson, & P. Whitney, 2003). Nonetheless, there is sufficiently strong evidence to sustain our original…

  11. Decision 99-18: Range Petroleum Corporation application for a well licence, Sturgeon Lake Area

    International Nuclear Information System (INIS)

    1999-07-01

    Range Petroleum Corporation (Range) applied to the Alberta Energy and Utilities Board (EUB) pursuant to Section 2.020 of the Oil and Gas Conservation Regulations for a well licence to drill a sour oil well from a surface location in Legal Subdivision 4, Section 34, West of the fifth Meridian, directionally to a bottom-hole location under Sturgeon Lake. The purpose of the proposed well would be to obtain sour oil production from the Leduc Formation. The well would be a Level 1 well because it would have a potential maximum hydrogen sulphide release rate of 0.0412 cubic m/s. The EUB received objections to the application from landowners, cattle ranchers, farmers, residents, and cottage owners in the area of the proposed well. The application and intervention were considered at a public hearing on 26 January 1999 in Grande Prairie, Alberta, and the Board viewed the proposed surface location, the previous Lds 3-2 surface location, and the surrounding area prior to the hearing. Having carefully considered the evidence, the Board believed that it would be possible to drill the proposed well safely and with minimal risk, subject to attached conditions. But in light of the unique setting of the area, including the residences and the road and lake configurations, and the difficulty that would exist preparing an effective environmental review process (ERP), the Board deferred its decision on the well licence application until an approved ERP is in place

  12. Decision 99-28: Mobil Oil Canada, Ltd., and Mobil Resources Ltd., - application for a well licence to drill a critical sour gas well LSD 4-36-27-28 W4, Crossfield Field, application No. 1037560

    International Nuclear Information System (INIS)

    1999-01-01

    On 12 February 1999, Mobil submitted Application No. 1037560 to the Alberta Energy and Utilities (EUB) Board on a routine basis, pursuant to Section 2.020 of the Oil and Gas Conservation Regulations, for a well licence to drill a critical sour gas well. The well would be drilled from a surface location in Legal Subdivision (LSD) 4 of Section 36, Township 27, Range 28, West of the 4th Meridian to a bottomhole location in LDS 7-36-27-28 W4M, with an 1100 m horizontal section. The aim of the 4-36 well was to obtain gas production from the Crossfield member. On 17 February 1999, the EUB issued Well Licence No. 221575 on the understanding that there were no outstanding objections to the 4-36 well. Mobil spudded the 4-36 well on 3 March 1999, drilled to 363 m and set surface casing. The EUB subsequently received objections to the application from area residents near the proposed well location. Accordingly, pursuant to Section 43 of the Energy Resources Conservation Act, the EUB directed that a public hearing be held to consider the application. The Board assessed in detail the effects that would likely result and the mitigative measures that would have to be taken to reduce any negative effects considering: the proposed well location, impacts of the proposed well, safety of the well, and public notification and consultation. Having carefully considered all the evidence, the EUB Board determined that Application No. 1037560 met all the EUB's regulatory requirements and was satisfied that appropriate measures were taken to ensure that public safety risks and impacts were minimized

  13. 40 CFR 112.13-112.15 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... POLLUTION PREVENTION Requirements for Animal Fats and Oils and Greases, and Fish and Marine Mammal Oils; and for Vegetable Oils, including Oils from Seeds, Nuts, Fruits, and Kernels. §§ 112.13-112.15 [Reserved] ...

  14. EUB Decision 2006-112 : Suncor Energy Inc. application for expansion of an oil sands mine (North Steepbank mine extension) and a bitumen upgrading facility (Voyageur Upgrader) in the Fort McMurray area

    International Nuclear Information System (INIS)

    2006-01-01

    Suncor Energy Inc. filed 2 applications to the Alberta Energy and Utilities Board for their proposed North Steepbank Mine Extension and Voyageur Upgrading Facility in the Fort McMurray area. This document provided an outline to the board of the location of the proposed projects, along with technical details concerning sulphur recovery, coke gasification, and by-product storage and use. The applications shared a common environmental impact assessment report, which presented details of tailings management programs; environmental effects to air, terrestrial resources, surface water, and groundwater; potential health effects to human populations; and traditional land use and ecological knowledge of the lands in the areas of the proposed upgrades. The social and economic effects of the projects were considered by the board, as well as the efforts of Suncor to engage with public consultation processes. It was noted that the projects are expected to provide $7.1 billion in federal taxes paid over the life of the project, in addition to $3.6 billion in provincial taxes and a further $23 million in municipal taxes. Details of several interventions filed by various First Nations groups were presented. It was noted that the Oil Sands Environmental Coalition (OSEC) has filed interventions stating concerns over consultation practices; cumulative effects; environmental monitoring; water usage; reclamation policies; and socio-economic issues. Various other groups have expressed concerns over the impacts of rapid development in the region and the subsequent strains on public infrastructure, housing and community resources. While the project is expected to provide employment, the current labour shortage in the region means that further development will be a disadvantage rather than a benefit to the communities in the region. Although a number of conditions were placed on Suncor before full acceptance of the project could be given, the board concluded that the Voyageur project was needed to increase the recovery of bitumen resources and provide the upgrading capacity required by Suncor for additional bitumen production from its mining and in situ projects. 1 fig

  15. Evaluation of the Priority Heuristic as a Descriptive Model of Risky Decision Making: Comment on Brandstatter, Gigerenzer, and Hertwig (2006)

    Science.gov (United States)

    Birnbaum, Michael H.

    2008-01-01

    E. Brandstatter, G. Gigerenzer, and R. Hertwig (2006) contended that their priority heuristic, a type of lexicographic semiorder model, is more accurate than cumulative prospect theory (CPT) or transfer of attention exchange (TAX) models in describing risky decisions. However, there are 4 problems with their argument. First, their heuristic is not…

  16. Section 112 hazardous air pollutants Clean Air Act Amendments of 1990; potential impact of fossil/NUC

    International Nuclear Information System (INIS)

    Cronmiller, R.E.

    1990-01-01

    Control of hazardous air pollutants under the Clean Air Act (CAA) goes back several decades. Section 112 of the 1970 CAA as amended in 1977 served as the national statutory basis for controlling hazardous air pollutants until the most recent 1990 Amendments. Following severe criticism of the effectiveness of the Act to address hazardous air pollutant issues and a pile of seemingly never ending lawsuits challenging the regulatory process, the U.S. Congress has substantially rewritten Section 112 in the 1990 CAA Amendments. Many provisions heretofore requiring findings or regulatory decisions by the Environmental Protection Agency (EPA) Administrator are now automatic in the sense that the decisions have already been made by the US Congress legislatively. Thus, the new Section 112 has eliminated many of the existing regulatory obstacles, or safeguards; this will likely result in sweeping new regulatory programs mandating extensive controls on many industrial activities. A much needed study program to address fossil fuel fired steam electric generating units' hazardous air emissions and to identify control alternatives to regulate these emissions, if regulation is required, was incorporated into new Section 112. Because of this study, the regulatory fate of these units under the new Section 112 remains highly uncertain. An extensive regulatory program addressing hazardous air pollutants of these utility units under Section 112 would dwarf electric utility costs associated with the new acid rain control program. First, this paper identifies major provisions of the old law and the resulting regulatory status for both coal and nuclear power facilities before addressing the new Section 112 under the 1990 CAA Amendments and potential implications for electric utilities specifically

  17. Characterization of Si(112) and In/Si(112) studied by SPA-LEED

    Energy Technology Data Exchange (ETDEWEB)

    Hoecker, Jan; Speckmann, Moritz; Schmidt, Thomas; Falta, Jens [Institute of Solid State Physics, University of Bremen, 28359 Bremen (Germany)

    2010-07-01

    High index surfaces are of strong interest in todays research because of the possibility to grow low dimensional structures. It has for instance already been shown that the adsorption of Ga can induce the formation of 1D metal chains on Si(112) (cf. Snijders et al., PRB 72, 2005). In this work we investigated the clean Si(112) surface and the adsorption of In on Si(112) to establish an analogy to Ga/Si(112) using spot profile analyzing low energy electron diffraction (SPA-LEED). By means of reciprocal space mapping we determined the bare Si(112) surface to be decomposed into alternating (5512) and (111) facets in [1 anti 10] direction with (2 x 1) and (7 x 7) reconstruction, respectively (cf. Baski et al., Surf. Sci. 392, 1997). With SPA-LEED we were able to observe the decreasing intensity of the facet spots in-situ while depositing In on Si(112) and thus reveal the smoothening of the surface due to the deposition of In. At saturation coverage we found a (3.x1) reconstruction, where x is dependent on the deposition temperature and changes from x=7 at 400 C to x=5 at 500 C. This leads us to the assumption that the reconstruction is not incommensurate but a mixture of (3 x 1) and (4 x 1) building blocks, which is very similar to the super structure of Ga on Si(112).

  18. Proactive compliance report 2004

    International Nuclear Information System (INIS)

    2005-01-01

    The Alberta Energy and Utilities Board (EUB) stipulates requirements to protect public safety, minimize environmental impacts, improve conservation, and ensure equity by promoting orderly and responsible energy development. Surveillance activities by the EUB, such as inspections and audits, ensures compliance with these requirements. This report presents statistical results of the enforcement ladder process (inspections, complaints, activities, major initiatives, and enforcement) for 2004 across ten EUB groups, including, Field Surveillance, Resources Applications Group, Operations Group, Environment Group, Utilities Branch, Facilities Applications Group, Corporate Compliance Group, Fort McMurray, Information and Dissemination Group, and Financial Management Group. When a noncompliance is identified, the EUB uses a process that has an established policy for EUB enforcement actions. Enforcement actions are determined by the severity of the noncompliance event and are escalated for subsequent noncompliance or failure to comply with the EUB's corrective order. Within the process, the EUB provides a grace period after an initial enforcement action. During this period, the EUB will take appropriate enforcement actions for subsequent noncompliances but will not escalate enforcement consequences. Enforcement consequences are escalated after the grace period has expired. 72 tabs

  19. 24 CFR 208.112 - Cost.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Cost. 208.112 Section 208.112... MULTIFAMILY SUBSIDIZED PROJECTS § 208.112 Cost. (a) The costs of the electronic transmission of the correctly... cost of contracting for those services, or the cost of centralizing the electronic transmission...

  20. PCaPAC 2006 Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Pavel Chevtsov; Matthew Bickley (Eds.)

    2007-03-30

    The 6-th international PCaPAC (Personal Computers and Particle Accelerator Controls) workshop was held at Jefferson Lab, Newport News, Virginia, from October 24-27, 2006. The main objectives of the conference were to discuss the most important issues of the use of PCs and modern IT technologies for controls of accelerators and to give scientists, engineers, and technicians a forum to exchange the ideas on control problems and their solutions. The workshop consisted of plenary sessions and poster sessions. No parallel sessions were held.Totally, more than seventy oral and poster presentations as well as tutorials were made during the conference, on the basis of which about fifty papers were submitted by the authors and included in this publication. This printed version of the PCaPAC 2006 Proceedings is published at Jefferson Lab according to the decision of the PCaPAC International Program Committee of October 26, 2006.

  1. 21 CFR 510.112 - Antibiotics used in veterinary medicine and for nonmedical purposes; required data.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Antibiotics used in veterinary medicine and for... DRUGS Specific Administrative Rulings and Decisions § 510.112 Antibiotics used in veterinary medicine and for nonmedical purposes; required data. (a) An ad hoc committee, Committee on the Veterinary...

  2. 7 CFR 1280.112 - Lamb products.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Lamb products. 1280.112 Section 1280.112 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Definitions § 1280.112 Lamb products. Lamb...

  3. 19 CFR 11.2 - Manufactured tobacco.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Manufactured tobacco. 11.2 Section 11.2 Customs... PACKING AND STAMPING; MARKING Packing and Stamping § 11.2 Manufactured tobacco. (a) If the invoice and entry presented for manufactured tobacco specify all the information necessary for prompt determination...

  4. 46 CFR 169.112 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Special consideration. 169.112 Section 169.112 Shipping... Provisions § 169.112 Special consideration. In applying the provisions of this part, the Officer in Charge, Marine Inspection, may give special consideration to departures from the specific requirements when...

  5. 22q11.2 Deletion syndrome is associated with perioperative outcome in tetralogy of Fallot.

    Science.gov (United States)

    Mercer-Rosa, Laura; Pinto, Nelangi; Yang, Wei; Tanel, Ronn; Goldmuntz, Elizabeth

    2013-10-01

    We sought to investigate the impact of 22q11.2 deletion on perioperative outcome in tetralogy of Fallot. We conducted a retrospective review of patients with tetralogy of Fallot who underwent complete surgical reconstruction at The Children's Hospital of Philadelphia between 1995 and 2006. Inclusion criteria included diagnosis of tetralogy of Fallot and known genotype. Fisher exact and Mann-Whitney tests were used for categoric and continuous variables, respectively. Regression analysis was used to determine whether deletion status predicts outcome. We studied 208 subjects with tetralogy of Fallot, 164 (79%) without and 44 (20%) with 22q11.2 deletion syndrome. There were no differences in sex, race, gestational age, age at diagnosis, admission weight, and duration of mechanical ventilation. Presenting anatomy, survival, complications and reoperations were also comparable between patients with and without 22q11.2 deletion syndrome. Those with 22q11.2 deletion syndrome had more aortopulmonary shunts preceding complete surgical repair (21% vs 7%, P = .02). This association was present after adjustment for presenting anatomy (stenosis, atresia, or absence of pulmonary valve and common atrioventricular canal) and surgical era. In addition, those with 22q11.2 deletion syndrome had longer cardiopulmonary bypass time (84 vs 72 minutes, P = .02) and duration of intensive care (6 vs 4 days, P = .007). Genotype affects early operative outcomes in tetralogy of Fallot resulting, in particular, in longer duration of intensive care. Future studies are required to determine factors contributing to such differences in this susceptible population. Copyright © 2013 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  6. 7 CFR 29.112 - Proper light.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Proper light. 29.112 Section 29.112 Agriculture... INSPECTION Regulations Inspectors, Samplers, and Weighers § 29.112 Proper light. Tobacco shall not be inspected or sampled for the purposes of the Act except when displayed in proper light for correct...

  7. 27 CFR 41.112 - Tax return.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Tax return. 41.112 Section 41.112 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF... States Deferred Payment of Tax in Puerto Rico on Tobacco Products § 41.112 Tax return. The internal...

  8. 21 CFR 163.112 - Breakfast cocoa.

    Science.gov (United States)

    2010-04-01

    ... CONSUMPTION CACAO PRODUCTS Requirements for Specific Standardized Cacao Products § 163.112 Breakfast cocoa. (a) Description. (1) Breakfast cocoa is the food prepared by pulverizing the material remaining after part of the... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Breakfast cocoa. 163.112 Section 163.112 Food and...

  9. The impact of the mode of thought in complex decisions: intuitive decisions are better

    Directory of Open Access Journals (Sweden)

    Marius eUsher

    2011-03-01

    Full Text Available A number of recent studies have reported that decision-quality is enhanced under conditions of inattention or distraction (unconscious-thought; Dijksterhuis, 2004; Dijksterhuis et al., 2006; Dijksterhuis & Nordgren, 2006. These reports have generated considerable controversy, for both experimental (problems of replication and theoretical reasons (interpretation. Here we report the results of four experiments. The first experiment replicates the unconscious thought effect, under conditions that validate and control the subjective criterion of decision quality. The second and third experiments examine the impact of a mode of thought manipulation (without distraction on decision quality in immediate decisions. Here we find that intuitive or affective manipulations improve decision quality compared to analytic/deliberation manipulations. The fourth experiment combines the two methods (distraction and mode of thought manipulations and demonstrates enhanced decision quality, in a situation that attempts to preserve ecological validity. The results are interpreted within a framework that is based on two interacting subsystems of decision-making: an affective/intuition based system and an analytic/deliberation system.

  10. 7 CFR 1260.112 - Federation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Federation. 1260.112 Section 1260.112 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS..., which includes as its State affiliates the qualified State beef councils. ...

  11. Dicty_cDB: VSK112 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VS (Link to library) VSK112 (Link to dictyBase) - - - Contig-U16538-1 VSK112P (Link... to Original site) VSK112F 515 VSK112Z 357 VSK112P 872 - - Show VSK112 Library VS (Link to library) Clone ID VSK112 (Link to dict...yBase) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U16538-1 Original site URL http://dict... 2004.12.25 Homology vs DNA Score E Sequences producing significant alignments: (bits) Value N Y17042 |Y17042.1 Dict...095O23 F, DNA sequence. 36 0.071 2 BM439182 |BM439182.1 IpLvr02248 Liver cDNA library Ict

  12. 36 CFR 406.112-406.129 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false [Reserved] 406.112-406.129 Section 406.112-406.129 Parks, Forests, and Public Property AMERICAN BATTLE MONUMENTS COMMISSION... BATTLE MONUMENTS COMMISSION §§ 406.112-406.129 [Reserved] ...

  13. 45 CFR 2490.112-2490.129 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false [Reserved] 2490.112-2490.129 Section 2490.112-2490.129 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON MEMORIAL... CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION §§ 2490.112-2490.129 [Reserved] ...

  14. 46 CFR 112.50-5 - Electric starting.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Electric starting. 112.50-5 Section 112.50-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Emergency Diesel and Gas Turbine Engine Driven Generator Sets § 112.50-5 Electric starting...

  15. 7 CFR 4287.112 - Interest rate adjustments.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Interest rate adjustments. 4287.112 Section 4287.112... Loans § 4287.112 Interest rate adjustments. (a) Reductions. The borrower, lender, and holder (if any) may collectively initiate a permanent or temporary reduction in the interest rate of the guaranteed...

  16. 41 CFR 101-1.112 - Change lines.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Change lines. 101-1.112 Section 101-1.112 Public Contracts and Property Management Federal Property Management Regulations System FEDERAL PROPERTY MANAGEMENT REGULATIONS GENERAL 1-INTRODUCTION 1.1-Regulation System § 101-1.112 Change...

  17. Hanford Tank 241-S-112 Residual Waste Composition and Leach Test Data

    Energy Technology Data Exchange (ETDEWEB)

    Cantrell, Kirk J.; Krupka, Kenneth M.; Geiszler, Keith N.; Lindberg, Michael J.; Arey, Bruce W.; Schaef, Herbert T.

    2008-08-29

    This report presents the results of laboratory characterization and testing of two samples (designated 20406 and 20407) of residual waste collected from tank S-112 after final waste retrieval. These studies were completed to characterize the residual waste and assess the leachability of contami¬nants from the solids. This is the first report from this PNNL project to describe the composition and leach test data for residual waste from a salt cake tank. All previous PNNL reports (Cantrell et al. 2008; Deutsch et al. 2006, 2007a, 2007b, 2007c) describing contaminant release models, and characterization and testing results for residual waste in single-shell tanks were based on samples from sludge tanks.

  18. 2006 Guidelines for Advancement and Promotion

    CERN Multimedia

    HR Department

    2006-01-01

    1. General The Director-General has now fixed the guidelines and schedule for the 2006 annual advancement review in the framework of the Merit Advancement and Promotion Scheme (MAPS). Procedures are set out in Administrative Circular 26 (Rev. 6). All decisions will be made by 1 July 2006. These now include career path changes for staff in Career Paths A to D. Departments are invited to comply strictly with the target date for the completion of the annual interviews which this year has been fixed at 15 March 2006. Group Leader evaluations are expected to be finalized by 13 April 2006. Exceptions due to particular circumstances (e.g. long-term absences) must be documented. The annual appraisal report should be completed using the electronic version in the EDH system. 2. Budget guidelines Within the annual advancement budget, the guideline allocations have been defined by the Director-General on a departmental basis for staff in Career Paths A to E and on a CERN-wide basis for staff in Career Paths F and ...

  19. 2006 Guidelines for Advancement and Promotion

    CERN Multimedia

    HR Department

    2006-01-01

    1. General The Director-General has now fixed the guidelines and schedule for the 2006 annual advancement review in the framework of the Merit Advancement and Promotion Scheme (MAPS). Procedures are set out in Administrative Circular 26 (Rev. 6). All decisions will be made by 1 July 2006. These now include career path changes for staff in Career Paths A to D. Departments are invited to comply strictly with the target date for the completion of the annual interviews which this year has been fixed at 15 March 2006. Group Leader evaluations are expected to be finalized by 13 April 2006. Exceptions due to particular circumstances (e.g. long-term absences) must be documented. The annual appraisal report should be completed using the electronic version in the EDH system. 2. Budget guidelines Within the annual advancement budget, the guideline allocations have been defined by the Director-General on a departmental basis for staff in Career Paths A to E and on a CERN-wide basis for staff in Career Paths F and G...

  20. 28 CFR 39.112-39.129 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false [Reserved] 39.112-39.129 Section 39.112-39.129 Judicial Administration DEPARTMENT OF JUSTICE ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE DEPARTMENT OF JUSTICE §§ 39.112-39.129 [Reserved] ...

  1. 42 CFR 51c.112 - Grantee accountability.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Grantee accountability. 51c.112 Section 51c.112 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR COMMUNITY HEALTH SERVICES General Provisions § 51c.112 Grantee accountability. (a) Accounting for grant award...

  2. 15q11.2 CNV affects cognitive, structural and functional correlates of dyslexia and dyscalculia.

    Science.gov (United States)

    Ulfarsson, M O; Walters, G B; Gustafsson, O; Steinberg, S; Silva, A; Doyle, O M; Brammer, M; Gudbjartsson, D F; Arnarsdottir, S; Jonsdottir, G A; Gisladottir, R S; Bjornsdottir, G; Helgason, H; Ellingsen, L M; Halldorsson, J G; Saemundsen, E; Stefansdottir, B; Jonsson, L; Eiriksdottir, V K; Eiriksdottir, G R; Johannesdottir, G H; Unnsteinsdottir, U; Jonsdottir, B; Magnusdottir, B B; Sulem, P; Thorsteinsdottir, U; Sigurdsson, E; Brandeis, D; Meyer-Lindenberg, A; Stefansson, H; Stefansson, K

    2017-04-25

    Several copy number variants have been associated with neuropsychiatric disorders and these variants have been shown to also influence cognitive abilities in carriers unaffected by psychiatric disorders. Previously, we associated the 15q11.2(BP1-BP2) deletion with specific learning disabilities and a larger corpus callosum. Here we investigate, in a much larger sample, the effect of the 15q11.2(BP1-BP2) deletion on cognitive, structural and functional correlates of dyslexia and dyscalculia. We report that the deletion confers greatest risk of the combined phenotype of dyslexia and dyscalculia. We also show that the deletion associates with a smaller left fusiform gyrus. Moreover, tailored functional magnetic resonance imaging experiments using phonological lexical decision and multiplication verification tasks demonstrate altered activation in the left fusiform and the left angular gyri in carriers. Thus, by using convergent evidence from neuropsychological testing, and structural and functional neuroimaging, we show that the 15q11.2(BP1-BP2) deletion affects cognitive, structural and functional correlates of both dyslexia and dyscalculia.

  3. 46 CFR 112.50-3 - Hydraulic starting.

    Science.gov (United States)

    2010-10-01

    ... POWER SYSTEMS Emergency Diesel and Gas Turbine Engine Driven Generator Sets § 112.50-3 Hydraulic starting. A hydraulic starting system must meet the following: (a) The hydraulic starting system must be a... 46 Shipping 4 2010-10-01 2010-10-01 false Hydraulic starting. 112.50-3 Section 112.50-3 Shipping...

  4. 49 CFR 28.112-28.129 - [Reserved

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false [Reserved] 28.112-28.129 Section 28.112-28.129 Transportation Office of the Secretary of Transportation ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE DEPARTMENT OF TRANSPORTATION §§ 28.112-28.129 [Reserved] ...

  5. 9 CFR 112.8 - For export only.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false For export only. 112.8 Section 112.8..., SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING § 112.8 For export... States shall apply to such biological product if exported from the United States except as otherwise...

  6. VALDOR 2006. Values in Decisions on Risk. Proceedings

    International Nuclear Information System (INIS)

    Andersson, Kjell

    2006-09-01

    Risk management, whether related to controversial facilities or the quotidian planning and response to disasters, involves a policy development and decision-making process that affects and is influenced by locally bounded communities (e.g. municipalities) as well as communities of interest (e.g. the business community and the anti-nuclear community). Environmental justice is only possible when all community perspectives are valued and incorporated into the risk management decision-making process. This raises issues of fairness such providing adequate resources for communities and ensuring equitable and fair socio-economic and political contexts. Public participation is widely seen as a means to take into account the different aspects of risk in the decision making processes. However, there are many models for public participation. Furthermore, different ideas for participation correlate with different models of democracy. The Symposium addressed theory and overall approaches as well as practical case studies. It gave insight into the problem of transparency in risk assessment and how procedures can be established to clarify the role of values versus facts, and to build trust. The following four our subject areas were covered by the conference: Nuclear waste management; Cleaning-up and remediation of contaminated sites; Risk assessment of mobile telephone systems; and Issues in biotechnology and food safety. Papers in the two first areas have been separately indexed for the database

  7. Suspension, abandonment, decontamination, and surface land reclamation of upstream oil and gas facilities : informational letter IL 98-2

    International Nuclear Information System (INIS)

    1998-01-01

    This release of the Alberta Energy and Utilities Board (EUB) is intended to clarify the jurisdictional roles of Alberta Environmental Protection (AEP) and the EUB with regard to their respective responsibilities for the regulation of the suspension, abandonment, decontamination and surface land reclamation of active and inactive upstream oil and gas facilities. The EUB, AEP and industrial operators all have separate roles and responsibilities when active and inactive upstream facilities are suspended or reclaimed. In the future, industry operators will have more interaction with the AEP during the decontamination of a site, while the EUB will concentrate on pollution prevention and abandonment of non-economic facilities. All oilfield waste generated from suspension, abandonment, decontamination, and surface land reclamation of an active or inactive upstream oil and gas facility will fall under the jurisdiction of the EUB. Contaminated soils, sludges, and waters that are physically removed as a result of decontamination activities are considered to be oilfield wastes. The regulatory responsibility between the AEP and the EUB remains unchanged for the reclamation process of on-lease and off-lease spills, releases or pipeline breaks. Industry operators are no longer allowed to discharge any produced liquid to earthen pits or ponds and are encouraged to reclaim existing ones. 3 figs

  8. 47 CFR 25.112 - Defective applications.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Defective applications. 25.112 Section 25.112 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES SATELLITE COMMUNICATIONS... internationally for such operations under the Radio Regulations of the International Telecommunication Union. (b...

  9. 13 CFR 112.7 - Illustrative applications.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Illustrative applications. 112.7 Section 112.7 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NONDISCRIMINATION IN FEDERALLY... or recruitment advertising, employment, layoff or termination, upgrading, demotion, or transfer...

  10. The european emergency number 112 - the questionnaire

    Directory of Open Access Journals (Sweden)

    Krzysztof Goniewicz

    2017-07-01

    Conclusions. Most of the respondents (92% identify the 112 number as an emergency number that allows them to connect to emergency services from anywhere in the European Union. A significant number of respondents (47% identify the 112 number as an emergency number in Poland. One in three respondents will use the 999 number to contact the emergency services as a witness to an emergency in Poland. Non-medical university students more often (63% will use the 112 emergency number than medical college students (41%. Respondents (98% confirmed the usefulness of a unified emergency number throughout Europe, but decided that they were not sufficiently informed about 112 as the European emergency number.

  11. Alberta Energy and Utilities Board, regulatory highlights for 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-01

    This new publication informs readers about what the Alberta Energy and Utilities Board (EUB) did in the past year, including important regulatory issues, trends and initiatives. The EUB is an agency of the provincial government, established to regulate Alberta`s energy resource and utility sectors. It is part of the Alberta Ministry of Energy. The four main functions of the Board are regulatory initiatives, license applications, enforcement and information. This publication summarized the EUB`s position regarding flaring (both solution gas flaring and well test flaring), and Board activities in the areas of animal health concerns, the gas over bitumen controversy, the deregulation of the electric industry and what it means to the EUB, improvements in data quality as a result of improved industry compliance in reporting, and a variety of issues related to the oil sands and the negotiated settlement process. Also, the Board has been proactive in the area of oilfield waste management guidelines, proliferation policies for gas processing facilities, sulphur recovery guidelines, and the expansion of the orphan well program to include facilities and pipelines. As a measure of the success of the EUB, a recent survey of 19 randomly selected focus groups praised EUB for its impartiality, fair and equitable enforcement and independence. It was also praised for its technically competent and experienced staff, its access to quality information and the clarity of its mandate, regulatory requirements and processes. The Board`s efforts in the area of timely stakeholder consultation was highlighted. tabs., figs.

  12. 28 CFR 11.2 - Pilot program.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Pilot program. 11.2 Section 11.2 Judicial... Pilot program. The Assistant Attorney General for Administration, in consultation with the Executive Office for United States Attorneys, shall designate the districts that will participate in the pilot...

  13. 13 CFR 112.3 - Discrimination prohibited.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Discrimination prohibited. 112.3... ASSISTED PROGRAMS OF SBA-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 § 112.3 Discrimination... be otherwise subjected to discrimination by any business or other activity. (b) Specific...

  14. Harmonization of industrial and oilfield waste management issues in Alberta

    International Nuclear Information System (INIS)

    Halla, S.

    1999-01-01

    There has been an ongoing discussion concerning the harmonization of waste management requirements within Alberta between the Alberta Energy and Utilities Board (EUB) and Alberta Environment (AENV), with the ultimate goal of publishing a memorandum of understanding (MOU) that will lay out the division of responsibilities between the two authorities on this matter. An overview is included of waste management in Alberta and of the harmonization agreements attained to date, with a stress on oil field waste issues. The EUB and AENV developed a MOE on the harmonization of waste management in Alberta, and a discussion is made of the concept of equivalency, which is used in the development of 'EUB guide 58: oilfield waste management requirements for the upstream petroleum industry' and will be a guiding principle for the MOU. Although the EUB's processes for waste management will not be exactly the same as AENV's, the EUB has made the commitment that, as a minimum, the requirements will provide the same level of environmental protection and public safety equivalent to that provided by AENV

  15. 38 CFR 4.112 - Weight loss.

    Science.gov (United States)

    2010-07-01

    .... The term “inability to gain weight” means that there has been substantial weight loss with inability... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Weight loss. 4.112... DISABILITIES Disability Ratings The Digestive System § 4.112 Weight loss. For purposes of evaluating conditions...

  16. New results on elements 111 and 112

    International Nuclear Information System (INIS)

    Hofmann, S.; Hessberger, F.P.; Ackermann, D.

    2002-01-01

    Experiments on the synthesis and identification of the nuclei 272 111 and 277 112 were performed in order to confirm previous results. Three additional decay chains were measured in the reaction 64 Ni + 209 Bi → 273 111 * . The study revealed considerably improved data on the decay chain originating from 272 111. One additional chain was measured in the reaction 70 Zn + 208 Pb → 278 112 * . The decay properties of the chain starting at 277 112 are in excellent agreement with the second chain of the first experiment down to 265 Sg, where the new chain ends by a previously unknown spontaneous-fission branch. A re-analysis of all data on elements 110, 111, and 112 measured at GSI since 1994 (a total of 34 decay chains was investigated) revealed that for 2 chains (second chain of 269 110 measured in 1994 and first chain of 277 112 measured in 1996) the results of the new analysis differed from the previous one. In all other cases the earlier data are exactly reproduced. (orig.)

  17. Special issue on activity-travel decision processes

    NARCIS (Netherlands)

    Doherty, S.; Ettema, D.F.

    2006-01-01

    Before you lies the 2006 TRB (Transportation Research Board) Special Issue of Transportation comprising selected papers presented at the 2006 Annual Meeting of the TRB in sessions sponsored by the Travel Behavior and Values committee on activity-travel decision processes. We are pleased to serve

  18. Alberta Energy and Utilities Board, regulatory highlights for 1998

    International Nuclear Information System (INIS)

    1999-01-01

    This new publication informs readers about what the Alberta Energy and Utilities Board (EUB) did in the past year, including important regulatory issues, trends and initiatives. The EUB is an agency of the provincial government, established to regulate Alberta's energy resource and utility sectors. It is part of the Alberta Ministry of Energy. The four main functions of the Board are regulatory initiatives, license applications, enforcement and information. This publication summarized the EUB's position regarding flaring (both solution gas flaring and well test flaring), and Board activities in the areas of animal health concerns, the gas over bitumen controversy, the deregulation of the electric industry and what it means to the EUB, improvements in data quality as a result of improved industry compliance in reporting, and a variety of issues related to the oil sands and the negotiated settlement process. Also, the Board has been proactive in the area of oilfield waste management guidelines, proliferation policies for gas processing facilities, sulphur recovery guidelines, and the expansion of the orphan well program to include facilities and pipelines. As a measure of the success of the EUB, a recent survey of 19 randomly selected focus groups praised EUB for its impartiality, fair and equitable enforcement and independence. It was also praised for its technically competent and experienced staff, its access to quality information and the clarity of its mandate, regulatory requirements and processes. The Board's efforts in the area of timely stakeholder consultation was highlighted. tabs., figs

  19. 13 CFR Appendix A to Part 112 - Appendix A to Part 112

    Science.gov (United States)

    2010-01-01

    ... FEDERALLY ASSISTED PROGRAMS OF SBA-EFFECTUATION OF TITLE VI OF THE CIVIL RIGHTS ACT OF 1964 Pt. 112, App. A...—economic injury Small Business Act, sec. 7(b)(4). Other Federal Financial Assistance Women's business...

  20. 46 CFR 112.01-20 - Final emergency power source.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Final emergency power source. 112.01-20 Section 112.01-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS Definitions of Emergency Lighting and Power Systems § 112.01-20 Final emergency...

  1. 9 CFR 112.6 - Packaging biological products.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Packaging biological products. 112.6... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS PACKAGING AND LABELING § 112.6 Packaging biological products. (a) Each multiple-dose final container of a biological product...

  2. 46 CFR 112.01-15 - Temporary emergency power source.

    Science.gov (United States)

    2010-10-01

    ... EMERGENCY LIGHTING AND POWER SYSTEMS Definitions of Emergency Lighting and Power Systems § 112.01-15 Temporary emergency power source. A temporary emergency power source is one of limited capacity that carries... 46 Shipping 4 2010-10-01 2010-10-01 false Temporary emergency power source. 112.01-15 Section 112...

  3. 1986-2006 Türkiye Ekonomisinin Performans Değerlendirmesi(Performance Analysis of Turkish Economy Between 1986-2006

    Directory of Open Access Journals (Sweden)

    Ali ELEREN

    2008-01-01

    Full Text Available When national and internetional competition are mentioned what firstly comes to mind has an economic competition. That is why critics on governments focus especially on economy politics and its results. In this study, the performance of Turkey’s economy between 1986-2006 is analyzed by TOPSIS method which is one of the multi-criterion decision methods. This method has an advantage for letting to analyze all criteria together with considering spesific points.

  4. 7 CFR 1703.112 - Expedited telecommunications loans

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Expedited telecommunications loans 1703.112 Section... § 1703.112 Expedited telecommunications loans RUS will expedite consideration and determination of an application submitted by an RUS telecommunications borrower for a loan under the Act or an advance of such...

  5. Children's influence on family purchase decision in India.

    OpenAIRE

    Desai, Tanvi

    2008-01-01

    The importance of children in purchase decision making has grown over the years. They not only make purchase decisions for personal consumption but they also influence family purchase decision-making (Kaur and Singh, 2006). This research looks at available literature, which is discussed with respect to children influence on product categories, decision-making stages, socialising agents like parents, peers and media and role of family communication in purchase decision making. Demographic vari...

  6. 46 CFR 112.55-15 - Capacity of storage batteries.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Capacity of storage batteries. 112.55-15 Section 112.55... LIGHTING AND POWER SYSTEMS Storage Battery Installation § 112.55-15 Capacity of storage batteries. (a) A storage battery for an emergency lighting and power system must have the capacity— (1) To close all...

  7. 19 CFR 112.46 - Report of loss or theft.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Report of loss or theft. 112.46 Section 112.46... TREASURY CARRIERS, CARTMEN, AND LIGHTERMEN Identification Cards § 112.46 Report of loss or theft. The loss or theft of an identification card shall be promptly reported by the cardholder to the port director. ...

  8. Are patient decision aids the best way to improve clinical decision making? Report of the IPDAS Symposium.

    Science.gov (United States)

    Holmes-Rovner, Margaret; Nelson, Wendy L; Pignone, Michael; Elwyn, Glyn; Rovner, David R; O'Connor, Annette M; Coulter, Angela; Correa-de-Araujo, Rosaly

    2007-01-01

    This article reports on the International Patient Decision Aid Standards Symposium held in 2006 at the annual meeting of the Society for Medical Decision Making in Cambridge, Massachusetts. The symposium featured a debate regarding the proposition that "decision aids are the best way to improve clinical decision making.'' The formal debate addressed the theoretical problem of the appropriate gold standard for an improved decision, efficacy of decision aids, and prospects for implementation. Audience comments and questions focused on both theory and practice: the often unacknowledged roots of decision aids in expected utility theory and the practical problems of limited patient decision aid implementation in health care. The participants' vote on the proposition was approximately half for and half against.

  9. DOE Hydrogen Program: 2006 Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    Milliken, J.

    2006-09-01

    This report summarizes comments from the Peer Review Panel at the FY 2006 DOE Hydrogen Program Annual Merit Review, held on May 16-19, 2006, in Arlington, Virginia. The projects evaluated support the Department of Energy and President Bush's Hydrogen Initiative. The results of this merit review and peer evaluation are major inputs used by DOE to make funding decisions. Project areas include hydrogen production and delivery; hydrogen storage; fuel cells; technology validation; safety, codes and standards; education; and systems analysis.

  10. PS1-12sk IS A PECULIAR SUPERNOVA FROM A He-RICH PROGENITOR SYSTEM IN A BRIGHTEST CLUSTER GALAXY ENVIRONMENT

    International Nuclear Information System (INIS)

    Sanders, N. E.; Soderberg, A. M.; Foley, R. J.; Chornock, R.; Milisavljevic, D.; Margutti, R.; Drout, M. R.; Moe, M.; Berger, E.; Brown, W. R.; Lunnan, R.; Smartt, S. J.; Fraser, M.; Kotak, R.; Magill, L.; Smith, K. W.; Wright, D.; Huang, K.; Urata, Y.; Mulchaey, J. S.

    2013-01-01

    We report on our discovery and observations of the Pan-STARRS1 supernova (SN) PS1-12sk, a transient with properties that indicate atypical star formation in its host galaxy cluster or pose a challenge to popular progenitor system models for this class of explosion. The optical spectra of PS1-12sk classify it as a Type Ibn SN (SN Ibn; cf. SN 2006jc), dominated by intermediate-width (3 × 10 3 km s –1 ) and time variable He I emission. Our multi-wavelength monitoring establishes the rise time dt ∼ 9-23 days and shows an NUV-NIR spectral energy distribution with temperature ∼> 17 × 10 3 K and a peak magnitude of M z = –18.88 ± 0.02 mag. SN Ibn spectroscopic properties are commonly interpreted as the signature of a massive star (17-100 M ☉ ) explosion within an He-enriched circumstellar medium. However, unlike previous SNe Ibn, PS1-12sk is associated with an elliptical brightest cluster galaxy, CGCG 208–042 (z = 0.054) in cluster RXC J0844.9+4258. The expected probability of an event like PS1-12sk in such environments is low given the measured infrequency of core-collapse SNe in red-sequence galaxies compounded by the low volumetric rate of SN Ibn. Furthermore, we find no evidence of star formation at the explosion site to sensitive limits (Σ Hα ∼ –3 M ☉ yr –1 kpc –2 ). We therefore discuss white dwarf binary systems as a possible progenitor channel for SNe Ibn. We conclude that PS1-12sk represents either a fortuitous and statistically unlikely discovery, evidence for a top-heavy initial mass function in galaxy cluster cooling flow filaments, or the first clue suggesting an alternate progenitor channel for SNe Ibn.

  11. 29 CFR 778.112 - Day rates and job rates.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Day rates and job rates. 778.112 Section 778.112 Labor... Requirements Principles for Computing Overtime Pay Based on the âregular Rateâ § 778.112 Day rates and job rates. If the employee is paid a flat sum for a day's work or for doing a particular job, without regard...

  12. A Multi-institution, Retrospective Analysis of Cervix Intracavitary Brachytherapy Treatments. Part 1: Is EQD2 Good Enough for Reporting Radiobiological Effects?

    Science.gov (United States)

    Fields, Emma C; Melvani, Rakhi; Hajdok, George; D'Souza, David; Jones, Bernard; Stuhr, Kelly; Diot, Quentin; Fisher, Christine M; Mukhopadhyay, Nitai; Todor, Dorin

    2017-09-01

    When brachytherapy doses are reported or added, biologically effective dose (BED) minimum dose covering 90% of the volume (D90) is used as if dose is delivered uniformly to the target. Unlike BED(D90), equivalent uniform BED (EUBED) and generalized biologically equivalent uniform dose (gBEUD) are quantities that integrate dose inhomogeneity. Here we compared BED(D90) and equivalent uniform BED (EUBED)/gBEUD in 3 settings: (1) 2 sites using tandem and ovoid (T&O) but different styles of implants; (2) 2 sites using different devices-T&O and tandem and ring (T&R)-and different styles; and (3) the same site using T&O and T&R with the same style. EUBED and gBEUD were calculated for 260 fractions from 3 institutions using BED(α/β = 10 Gy). EUBED uses an extra parameter α with smaller values associated with radioresistant tumors. Similarly, gBEUD uses a, which places variable emphasis on hot/cold spots. Distributions were compared using the Kolmogorov-Smirnoff test at 5% significance. For the 2 sites using T&O, the distribution of EUBED-BED(D90) was not different for values of α = 0.5 to 0.3 Gy -1 but was statistically different for values of α = 0.15 to 0.05 Gy -1 (P=.01, .002). The mean percentage differences between EUBED and BED(D90) ranged from 20% to 100% for α = 0.5 Gy -1 to 0.05 Gy -1 . Using gBEUD-BED(D90), the P values indicate the distributions to be similar for a = -10 but to be significantly different for other values of a (-5, -1, 1). Between sites and at the same site using T&O versus T&R, the distributions were statistically different with EUBED/gBEUD irrespective of parameter values at which these quantities were computed. These differences indicate that EUBED/gBEUD capture differences between the techniques and applicators that are not detected by the BED(D90). BED(D90) is unable to distinguish between plans created by different devices or optimized differently. EUBED/gBEUD distinguish between dose distributions created by different

  13. 12 CFR 410.112-410.129 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false [Reserved] 410.112-410.129 Section 410.112-410.129 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY EXPORT-IMPORT BANK OF THE UNITED STATES §§ 410...

  14. PSI Scientific Report 2006

    International Nuclear Information System (INIS)

    Schlaepfer-Miller, J.

    2007-04-01

    Selected highlights in this years report include muon spin studies and investigations of polymer films, the chemical properties of element 112 and the antitumour effects of radionuclides. In its fifth year of operation, results from the SLS include shedding light on superconductivity and understanding magnetism at the nanoscale. From the energy research departments we hear that progress has been achieved in the conversion of biomass to methane fuel, and towards the generation of hydrogen by solar thermochemistry. Combustion research, among other themes, focused on efficiency in gas turbine processes. Neutronic studies dealt with safety aspects of present nuclear reactors, thermal hydraulics with reactors of the future. safety is also the issue in how ions migrate in waste repositories or in the operation of the MEGAPIE liquid metal target. The Competence Center Energy and Mobility of the ETH domain, for which PSI acts as he facilitator, started operation at the beginning of 2006, and several projects have been successfully launched. The reports in this volume are only a fraction of the varied research undertaken at PSI in the past year; for more information visit our website www.psi.ch. (author)

  15. PSI Scientific Report 2006

    Energy Technology Data Exchange (ETDEWEB)

    Schlaepfer-Miller, J [ed.

    2007-04-15

    Selected highlights in this years report include muon spin studies and investigations of polymer films, the chemical properties of element 112 and the antitumour effects of radionuclides. In its fifth year of operation, results from the SLS include shedding light on superconductivity and understanding magnetism at the nanoscale. From the energy research departments we hear that progress has been achieved in the conversion of biomass to methane fuel, and towards the generation of hydrogen by solar thermochemistry. Combustion research, among other themes, focused on efficiency in gas turbine processes. Neutronic studies dealt with safety aspects of present nuclear reactors, thermal hydraulics with reactors of the future. safety is also the issue in how ions migrate in waste repositories or in the operation of the MEGAPIE liquid metal target. The Competence Center Energy and Mobility of the ETH domain, for which PSI acts as he facilitator, started operation at the beginning of 2006, and several projects have been successfully launched. The reports in this volume are only a fraction of the varied research undertaken at PSI in the past year; for more information visit our website www.psi.ch. (author)

  16. Tank characterization data report: Tank 241-C-112

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, B.C.; Borsheim, G.L.; Jensen, L.

    1993-09-01

    Tank 241-C-112 is a Hanford Site Ferrocyanide Watch List tank that was most recently sampled in March 1992. Analyses of materials obtained from tank 241-C-112 were conducted to support the resolution of the Ferrocyanide Unreviewed Safety Question (USQ) and to support Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Milestone M-10-00. Analysis of core samples obtained from tank 241-C-112 strongly indicates that the fuel concentration in the tank waste will not support a propagating exothermic reaction. Analysis of the process history of the tank as well as studies of simulants provided valuable information about the physical and chemical condition of the waste. This information, in combination with the analysis of the tank waste, sup ports the conclusion that an exothermic reaction in tank 241-C-112 is not plausible. Therefore, the contents of tank 241-C-112 present no imminent threat to the workers at the Hanford Site, the public, or the environment from its forrocyanide inventory. Because an exothermic reaction is not credible, the consequences of this accident scenario, as promulgated by the General Accounting Office, are not applicable.

  17. Tank characterization data report: Tank 241-C-112

    International Nuclear Information System (INIS)

    Simpson, B.C.; Borsheim, G.L.; Jensen, L.

    1993-09-01

    Tank 241-C-112 is a Hanford Site Ferrocyanide Watch List tank that was most recently sampled in March 1992. Analyses of materials obtained from tank 241-C-112 were conducted to support the resolution of the Ferrocyanide Unreviewed Safety Question (USQ) and to support Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Milestone M-10-00. Analysis of core samples obtained from tank 241-C-112 strongly indicates that the fuel concentration in the tank waste will not support a propagating exothermic reaction. Analysis of the process history of the tank as well as studies of simulants provided valuable information about the physical and chemical condition of the waste. This information, in combination with the analysis of the tank waste, sup ports the conclusion that an exothermic reaction in tank 241-C-112 is not plausible. Therefore, the contents of tank 241-C-112 present no imminent threat to the workers at the Hanford Site, the public, or the environment from its forrocyanide inventory. Because an exothermic reaction is not credible, the consequences of this accident scenario, as promulgated by the General Accounting Office, are not applicable

  18. Duplication of 17(p11.2p11.2) in a male child with autism and severe language delay.

    Science.gov (United States)

    Nakamine, Alisa; Ouchanov, Leonid; Jiménez, Patricia; Manghi, Elina R; Esquivel, Marcela; Monge, Silvia; Fallas, Marietha; Burton, Barbara K; Szomju, Barbara; Elsea, Sarah H; Marshall, Christian R; Scherer, Stephen W; McInnes, L Alison

    2008-03-01

    Duplications of 17(p11.2p11.2) have been associated with various behavioral manifestations including attention deficits, obsessive-compulsive symptoms, autistic traits, and language delay. We are conducting a genetic study of autism and are screening all cases for submicroscopic chromosomal abnormalities, in addition to standard karyotyping, and fragile X testing. Using array-based comparative genomic hybridization analysis of data from the Affymetrix GeneChip(R) Human Mapping Array set, we detected a duplication of approximately 3.3 Mb on chromosome 17p11.2 in a male child with autism and severe expressive language delay. The duplication was confirmed by measuring the copy number of genomic DNA using quantitative polymerase chain reaction. Gene expression analyses revealed increased expression of three candidate genes for the Smith-Magenis neurobehavioral phenotype, RAI1, DRG2, and RASD1, in transformed lymphocytes from Case 81A, suggesting gene dosage effects. Our results add to a growing body of evidence suggesting that duplications of 17(p11.2p11.2) result in language delay as well as autism and related phenotypes. As Smith-Magenis syndrome is also associated with language delay, a gene involved in acquisition of language may lie within this interval. Whether a parent of origin effect, gender of the case, the presence of allelic variation, or changes in expression of genes outside the breakpoints influence the resultant phenotype remains to be determined. (c) 2007 Wiley-Liss, Inc.

  19. 27 CFR 20.112 - Special industrial solvents general-use formula.

    Science.gov (United States)

    2010-04-01

    ... solvents general-use formula. 20.112 Section 20.112 Alcohol, Tobacco Products and Firearms ALCOHOL AND... AND RUM Formulas and Statements of Process General-Use Formulas § 20.112 Special industrial solvents general-use formula. (a) A special industrial solvent is any article made with any other ingredients...

  20. 40 CFR Appendix C to Part 112 - Substantial Harm Criteria

    Science.gov (United States)

    2010-07-01

    ... to Part 112 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS OIL POLLUTION PREVENTION Pt. 112, App. C Appendix C to Part 112—Substantial Harm Criteria 1.0Introduction The..., except in the Gulf of Mexico. In the Gulf of Mexico, it means the area shoreward of the lines of...

  1. 7 CFR 1160.112 - Research.

    Science.gov (United States)

    2010-01-01

    ... and Orders; Milk), DEPARTMENT OF AGRICULTURE FLUID MILK PROMOTION PROGRAM Fluid Milk Promotion Order Definitions § 1160.112 Research. Research means market research to support advertising and promotion efforts...

  2. 46 CFR 112.50-7 - Compressed air starting.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Compressed air starting. 112.50-7 Section 112.50-7... air starting. A compressed air starting system must meet the following: (a) The starting, charging... air compressors addressed in paragraph (c)(3)(i) of this section. (b) The compressed air starting...

  3. 34 CFR 300.112 - Individualized education programs (IEP).

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Individualized education programs (IEP). 300.112 Section 300.112 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF... education programs (IEP). The State must ensure that an IEP, or an IFSP that meets the requirements of...

  4. 22q11.2 deletion syndrome

    Science.gov (United States)

    McDonald-McGinn, Donna M.; Sullivan, Kathleen E.; Marino, Bruno; Philip, Nicole; Swillen, Ann; Vorstman, Jacob A. S.; Zackai, Elaine H.; Emanuel, Beverly S.; Vermeesch, Joris R.; Morrow, Bernice E.; Scambler, Peter J.; Bassett, Anne S.

    2016-01-01

    22q11.2 deletion syndrome (22q11.2DS) is the most common chromosomal microdeletion disorder, estimated to result mainly from de novo non-homologous meiotic recombination events occurring in approximately 1 in every 1,000 fetuses. The first description in the English language of the constellation of findings now known to be due to this chromosomal difference was made in the 1960s in children with DiGeorge syndrome, who presented with the clinical triad of immunodeficiency, hypoparathyroidism and congenital heart disease. The syndrome is now known to have a heterogeneous presentation that includes multiple additional congenital anomalies and later-onset conditions, such as palatal, gastrointestinal and renal abnormalities, autoimmune disease, variable cognitive delays, behavioural phenotypes and psychiatric illness — all far extending the original description of DiGeorge syndrome. Management requires a multidisciplinary approach involving paediatrics, general medicine, surgery, psychiatry, psychology, interventional therapies (physical, occupational, speech, language and behavioural) and genetic counselling. Although common, lack of recognition of the condition and/or lack of familiarity with genetic testing methods, together with the wide variability of clinical presentation, delays diagnosis. Early diagnosis, preferably prenatally or neonatally, could improve outcomes, thus stressing the importance of universal screening. Equally important, 22q11.2DS has become a model for understanding rare and frequent congenital anomalies, medical conditions, psychiatric and developmental disorders, and may provide a platform to better understand these disorders while affording opportunities for translational strategies across the lifespan for both patients with 22q11.2DS and those with these associated features in the general population. PMID:27189754

  5. The new element 112. Short note

    International Nuclear Information System (INIS)

    Hofmann, S.; Ninov, V.; Hessberger, F.P.; Armbruster, P.; Folger, H.; Muenzenberg, G.; Schoett, H.J.; Popeko, A.G.; Yeremin, A.V.; Saro, S.; Janik, R.; Leino, M.

    1996-02-01

    The new element 112 was produced and identified unambigiously in an experiment at SHIP, GSI Darmstadt. Two decay chains of the isotope 277 112 were observed in irradiations of 208 Pb targets with 70 Zn projectiles of 344 MeV kinetic energy. The isotope decays by emission of α particles with a half-life of (240 -90 +430 ) μs. Two different α energies of (11.649±20) keV and (11.454±20) keV were measured for the two observed decays. The cross-section measured in three weeks of irradiations is (1.0 -0.4 +18 ) pb. (orig.)

  6. Movement and counter-movement: a history of abortion law reform and the backlash in Colombia 2006-2014.

    Science.gov (United States)

    Ruibal, Alba

    2014-11-01

    In 2006, the Constitutional Court of Colombia issued Decision C-355/2006, which liberalized the country's abortion law. The reform was groundbreaking in its argumentation, being one of the first judicial decisions in the world to uphold abortion rights on equality grounds, and the first by a constitutional court to rule on the constitutionality of abortion within a human rights framework. It was also the first of a series of reforms that would liberalize the abortion regulation in four other Latin American countries. The Colombian case is also notable for the process of strategic litigation carried out by feminist organizations after the Court's decision, in order to ensure its implementation and counter the opposition from conservative actors working in State institutions, as well as for the active role played by the Court in that process. Based on fieldwork carried out in Colombia in 2013, this article analyzes the process of progressive implementation and reactionary backlash after Decision C-355/2006, with an emphasis on strategic litigation by the feminist movement and subsequent decisions by the Constitutional Court, which consolidated its jurisprudence in the field of abortion rights. It highlights the role of both feminists and of conservative activists within State institutions as opposing social movements, and the dynamics of political and legal mobilization and counter-mobilization in that process. Copyright © 2014 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  7. PS1-12sk IS A PECULIAR SUPERNOVA FROM A He-RICH PROGENITOR SYSTEM IN A BRIGHTEST CLUSTER GALAXY ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    Sanders, N. E.; Soderberg, A. M.; Foley, R. J.; Chornock, R.; Milisavljevic, D.; Margutti, R.; Drout, M. R.; Moe, M.; Berger, E.; Brown, W. R.; Lunnan, R. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Smartt, S. J.; Fraser, M.; Kotak, R.; Magill, L.; Smith, K. W.; Wright, D. [Astrophysics Research Centre, School of Maths and Physics, Queens University, Belfast BT7 1NN (United Kingdom); Huang, K. [Academia Sinica Institute of Astronomy and Astrophysics, Taipei 106, Taiwan (China); Urata, Y. [Institute of Astronomy, National Central University, Chung-Li 32054, Taiwan (China); Mulchaey, J. S., E-mail: nsanders@cfa.harvard.edu [Carnegie Observatories, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); and others

    2013-05-20

    We report on our discovery and observations of the Pan-STARRS1 supernova (SN) PS1-12sk, a transient with properties that indicate atypical star formation in its host galaxy cluster or pose a challenge to popular progenitor system models for this class of explosion. The optical spectra of PS1-12sk classify it as a Type Ibn SN (SN Ibn; cf. SN 2006jc), dominated by intermediate-width (3 Multiplication-Sign 10{sup 3} km s{sup -1}) and time variable He I emission. Our multi-wavelength monitoring establishes the rise time dt {approx} 9-23 days and shows an NUV-NIR spectral energy distribution with temperature {approx}> 17 Multiplication-Sign 10{sup 3} K and a peak magnitude of M{sub z} = -18.88 {+-} 0.02 mag. SN Ibn spectroscopic properties are commonly interpreted as the signature of a massive star (17-100 M{sub Sun }) explosion within an He-enriched circumstellar medium. However, unlike previous SNe Ibn, PS1-12sk is associated with an elliptical brightest cluster galaxy, CGCG 208-042 (z = 0.054) in cluster RXC J0844.9+4258. The expected probability of an event like PS1-12sk in such environments is low given the measured infrequency of core-collapse SNe in red-sequence galaxies compounded by the low volumetric rate of SN Ibn. Furthermore, we find no evidence of star formation at the explosion site to sensitive limits ({Sigma}{sub H{alpha}} {approx}< 2 Multiplication-Sign 10{sup -3} M{sub Sun} yr{sup -1} kpc{sup -2}). We therefore discuss white dwarf binary systems as a possible progenitor channel for SNe Ibn. We conclude that PS1-12sk represents either a fortuitous and statistically unlikely discovery, evidence for a top-heavy initial mass function in galaxy cluster cooling flow filaments, or the first clue suggesting an alternate progenitor channel for SNe Ibn.

  8. New Element no. 112 prepared from Zink and Lead

    DEFF Research Database (Denmark)

    Berg, Rolf W.

    1996-01-01

    The preparation of element no. 112 in the Periodic Table of the Elements has been reviewed in a popular scientific magazine.......The preparation of element no. 112 in the Periodic Table of the Elements has been reviewed in a popular scientific magazine....

  9. Genetic mapping of 14 avirulence genes in an EU-B04 × 1639 progeny of Venturia inaequalis.

    Science.gov (United States)

    Broggini, Giovanni A L; Bus, Vincent G M; Parravicini, Gabriella; Kumar, Satish; Groenwold, Remmelt; Gessler, Cesare

    2011-02-01

    Durable resistance to apple scab (Venturia inaequalis (Cke) Wint; anamorph Spilocaea pomi Fries) is one of the major goals of apple (Malus) breeding programs. Since current scab resistance breeding is heavily reliant on genes with gene-for-gene relationships, a good understanding of the genetic basis of host-pathogen interactions needs to be developed for this strategy to be successful. While the genomic organization of apple scab resistance genes has been studied extensively, little is known about the avirulence genes in the pathogen. The progeny of a cross of European V. inaequalis race (1) isolate EU-B04 and race (1,2,8,9) isolate 1639 was used to generate a genetic map based on microsatellite and AFLP markers, and investigated for inheritance of avirulence traits on 20 Malus accessions representing 17 scab resistance genes. The accessions comprised scab differential hosts (0), (1), (2), (8), and (9), and hosts carrying known as well as not previously reported secondary resistance genes, including some identified in crosses that have resistant accessions 'Geneva', 'Dolgo', Malus baccata jackii, M. micromalus, or 'Antonovka' in their pedigree. The latter genes appear to be narrow spectrum genes that showed gene-for-gene relationships as a segregation ratio of Avr:avr=1:1 was observed on 12 accessions, while a ratio of 3:1 was observed on five accessions and a ratio of 7:1 on one host. All progenies were shown to be pathogenic, as all of them were able to infect hosts (0) and (1). A genetic map consisting of 15 major linkage groups (LGs) and spanning 972cM was generated with the aid of 156 markers. The map position of 12 avirulence traits was determined: eight avirulence genes mapped into two separate clusters (1: AvrVdg2, AvrVv1, AvrVu1, AvrVrjrd; and 2: AvrVu2, AvrVh3.2, AvrVs1, AvrVu4), while four avirulence genes (AvrRvi8, AvrVv2, AvrVt57 and AvrVsv) mapped to different LGs. AvrRvi2 and AvrRvi9 also are genetically linked, but showed an interaction with Avr

  10. Carbon trends. July 2006; Tendances carbone. Juillet 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-15

    This newsletter makes a monthly synthesis of the European CO{sub 2} market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from June 2005 to June 2006), economic activity indicators (industrial production index from April 2005 to April 2006), confidence index of business leaders (from June 2005 to June 2006), changes in energy prices (from July 2005 to June 2006), CO{sub 2} quotas allocated to European Union countries and detailed indicators of CO{sub 2} market, climate, economic activity and energy prices. (J.S.)

  11. Carbon trends. May 2006; Tendances carbone. Mai 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-05-15

    This newsletter makes a monthly synthesis of the European CO{sub 2} market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from May 2005 to April 2006), economic activity indicators (industrial production from February 2005 to February 2006), confidence index of business leaders (from April 2005 to April 2006), changes in energy prices (from May 2005 to April 2006), CO{sub 2} quotas allocated to European Union countries and detailed indicators of CO{sub 2} market, climate, economic activity and energy prices. (J.S.)

  12. Carbon trends. June 2006; Tendances carbone. Juin 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    This newsletter makes a monthly synthesis of the European CO{sub 2} market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from June 2005 to May 2006), economic activity indicators (industrial production from March 2005 to March 2006), confidence index of business leaders (from May 2005 to May 2006), changes in energy prices (from June 2005 to May 2006), CO{sub 2} quotas allocated to European Union countries and detailed indicators of CO{sub 2} market, climate, economic activity and energy prices. (J.S.)

  13. 7 CFR 766.112 - Additional security for restructured loans.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Additional security for restructured loans. 766.112..., DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-SPECIAL Loan Servicing Programs § 766.112 Additional security for restructured loans. (a) If the borrower is delinquent prior to restructuring, the...

  14. 23 CFR 635.112 - Advertising for bids and proposals.

    Science.gov (United States)

    2010-04-01

    ... OPERATIONS CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.112 Advertising for bids and proposals. (a) No work shall be undertaken on any Federal-aid project, nor shall any project be advertised for bids... 23 Highways 1 2010-04-01 2010-04-01 false Advertising for bids and proposals. 635.112 Section 635...

  15. 10 CFR 455.112 - Davis-Bacon wage rate requirement.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Davis-Bacon wage rate requirement. 455.112 Section 455.112 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS... acquisition and installation of more than $5,000, any construction contract or subcontract in excess of $2,000...

  16. Childhood cognitive development in 22q11.2 deletion syndrome: case-control study.

    Science.gov (United States)

    Chawner, Samuel J R A; Doherty, Joanne L; Moss, Hayley; Niarchou, Maria; Walters, James T R; Owen, Michael J; van den Bree, Marianne B M

    2017-10-01

    Background 22q11.2 deletion syndrome (22q11.2DS) is associated with a high risk of childhood as well as adult psychiatric disorders, in particular schizophrenia. Childhood cognitive deterioration in 22q11.2DS has previously been reported, but only in studies lacking a control sample. Aims To compare cognitive trajectories in children with 22q11.2DS and unaffected control siblings. Method A longitudinal study of neurocognitive functioning (IQ, executive function, processing speed and attention) was conducted in children with 22q11.2DS ( n = 75, mean age time 1 ( T 1 ) 9.9, time 2 ( T 2 ) 12.5) and control siblings ( n = 33, mean age T 1 10.6, T 2 13.4). Results Children with 22q11.2DS exhibited deficits in all cognitive domains. However, mean scores did not indicate deterioration. When individual trajectories were examined, some participants showed significant decline over time, but the prevalence was similar for 22q11.2DS and control siblings. Findings are more likely to reflect normal developmental fluctuation than a 22q11.2DS-specific abnormality. Conclusions Childhood cognitive deterioration is not associated with 22q11.2DS. Contrary to previous suggestions, we believe it is premature to recommend repeated monitoring of cognitive function for identifying individual children with 22q11.2DS at high risk of developing schizophrenia. © The Royal College of Psychiatrists 2017.

  17. Swiss electricity statistics 2006; Schweizerische Elektrizitaetsstatistik 2006/Statistique suisse de l'electricite 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This comprehensive report made by the Swiss Federal Office of Energy (SFOE) presents the statistics on electricity production and usage in Switzerland for the year 2006. First of all, an overview of Switzerland's electricity supply in 2006 is presented. Details are noted of the amounts generated by different sources including nuclear, hydro-power, storage schemes and thermal power stations as well as energy transfer with neighbouring countries. A second chapter takes a look at the balance of imports and exports with illustrative flow diagrams along with tables for total figures from 1950 through to 2006. For the summer and winter periods, figures from 1995 to 2006 are presented. The third chapter examines the production of electricity in the various types of power stations and the developments over the years 1950 to 2006, whereby, for example, statistics on regional generation and power station type are looked at. The fourth chapter looks at electricity consumption in various sectors from 1983 to 2006 and compares the figures with international data. The fifth chapter looks at generation, consumption and loading on particular, selected days and chapter six considers energy exchange with Switzerland's neighbours. Chapter seven takes a look at possibilities for extending generation facilities in the period up to 2013.

  18. 18 CFR 401.112 - Exempt information.

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Public Access to Records and Information § 401.112 Exempt... unwarranted invasion of personal privacy, (4) disclose the identity of a confidential source, (5) disclose...

  19. Psychopathology and cognition in children with 22q11.2 deletion syndrome

    Science.gov (United States)

    Niarchou, Maria; Zammit, Stanley; van Goozen, Stephanie H. M.; Thapar, Anita; Tierling, Hayley M.; Owen, Michael J.; van den Bree, Marianne B. M.

    2014-01-01

    Background Children with 22q11.2 deletion syndrome (22q11.2DS) have been reported to have high rates of cognitive and psychiatric problems. Aims To establish the nature and prevalence of psychiatric disorder and neurocognitive impairment in children with 22q11.2DS and test whether risk of psychopathology is mediated by the children’s intellectual impairment. Method Neurocognition and psychopathology were assessed in 80 children with 22q11.2DS (mean age 10.2 years, s.d. = 2.1) and 39 sibling controls (mean age 10.9 years, s.d. = 2.0). Results More than half (54%) of children with 22q11.2DS met diagnostic criteria for one or more DSM-IV-TR psychiatric disorder. These children had lower IQ (mean 76.8, s.d. = 13.0) than controls (mean 108.6, s.d. = 15.2) (Ppsychopathology was not mediated by intellectual impairment. Conclusions 22q11.2DS is not related to a specific psychiatric phenotype in children. Moreover, the deletion has largely independent effects on IQ and risk of psychopathology, indicating that psychopathology in 22q11.2DS is not a non-specific consequence of generalised cognitive impairment. PMID:24115343

  20. The dimensional structure of psychopathology in 22q11.2 Deletion Syndrome.

    Science.gov (United States)

    Niarchou, Maria; Moore, Tyler M; Tang, Sunny X; Calkins, Monica E; McDonald-McGuinn, Donna M; Zackai, Elaine H; Emanuel, Beverly S; Gur, Ruben C; Gur, Raquel E

    2017-09-01

    22q11.2 Deletion Syndrome (22q11.2DS) is one of the strongest known genetic risk factors for developing schizophrenia. Individuals with 22q11.2DS have high rates of neurodevelopmental disorders in childhood, while in adulthood ∼25% develop schizophrenia. Similar to the general population, high rates of comorbidity are common in 22q11.2DS. Employing a dimensional approach where psychopathology is examined at the symptom-level as complementary to diagnostic categories in a population at such high genetic risk for schizophrenia can help gain a better understanding of how psychopathology is structured as well as its genetic underpinnings. This is the first study to examine the dimensional structure of a wide spectrum of psychopathology in the context of a homogeneous genetic etiology like 22q11.2DS. We evaluated 331 individuals with 22q11.2DS, mean age (SD) = 16.9(8.7); 51% males, who underwent prospective comprehensive phenotyping. We sought to replicate previous findings by examining a bi-factor model that derives a general factor of psychopathology in addition to more specific dimensions of psychopathology (i.e., internalizing, externalizing and thought disorder). Psychopathology in 22q11.2DS was divided into one 'general psychopathology' factor and four specific dimensions (i.e., 'anxiety', 'mood', 'ADHD' and 'psychosis'). The 'psychosis' symptoms loaded strongly on the 'general psychopathology' factor. The similarity of the symptom structure of psychopathology between 22q11.2DS and community and clinical populations without the deletion indicate that 22q11.2DS can provide a model to explore alternative approaches to our current nosology. Our findings add to a growing literature indicating the need to reorganize current diagnostic classification systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. The Type II supernovae 2006V and 2006au

    DEFF Research Database (Denmark)

    Taddia, F.; Stritzinger, M. D.; Sollerman, J.

    2012-01-01

    curve evolution similar to that of SN 1987A. At the earliest epochs, SN 2006au also displays an initial dip which we interpret as the signature of the adiabatic cooling phase that ensues shock break-out. SNe 2006V and 2006au are both found to be bluer, hotter and brighter than SN 1987A. Spectra of SNe...

  2. Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements.

    Science.gov (United States)

    Demaerel, Wolfram; Hestand, Matthew S; Vergaelen, Elfi; Swillen, Ann; López-Sánchez, Marcos; Pérez-Jurado, Luis A; McDonald-McGinn, Donna M; Zackai, Elaine; Emanuel, Beverly S; Morrow, Bernice E; Breckpot, Jeroen; Devriendt, Koenraad; Vermeesch, Joris R

    2017-10-05

    Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no such inversions have been uncovered as of yet. Using fiber-FISH, we demonstrate that parents transmitting the de novo 3 Mb LCR22A-D 22q11.2 deletion, the reciprocal duplication, and the smaller 1.5 Mb LCR22A-B 22q11.2 deletion carry inversions of LCR22B-D or LCR22C-D. Hence, the inversions predispose chromosome 22q11.2 to meiotic rearrangements and increase the individual risk for transmitting rearrangements. Interestingly, the inversions are nested or flanking rather than coinciding with the deletion or duplication sizes. This finding raises the possibility that inversions are a prerequisite not only for 22q11.2 rearrangements but also for all NAHR-mediated genomic disorders. Copyright © 2017. Published by Elsevier Inc.

  3. Decision-Making Styles of Young Chinese, Motswana and ...

    African Journals Online (AJOL)

    BlignautAS

    ISSN 0378-5254 Journal of Family Ecology and Consumer Sciences, Vol 34, 2006. Decision-Making Styles of ... significantly influences shopping behaviour. Four dis- ..... Apparel is a high- involvement shopping item that is often bought for its.

  4. Adsorption of lithium-lanthanum films on W (112) face

    International Nuclear Information System (INIS)

    Gupalo, M.S.; Smereka, T.P.; Palyukh, B.M.; Babkin, G.V.

    1986-01-01

    The method of contact potential difference is employed to study the electron adsorption properties (the work function phi and adsorption heat q) lithium films on a lanthanized W(112) surface. It is found that the work function of mixed lithium-lanthanum films is intermediate between phi of the summands. The presence of lanthanum on a W(112) face reduces the adsorption heat of lithium

  5. 32 CFR 112.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN INDEBTEDNESS OF MILITARY PERSONNEL § 112.1 Purpose. This part: (a) Updates DoD policies and assigns responsibilities... U.S.C. 5520a(k). (b) Establishes responsibility for procedures implementing 5 U.S.C. 5520a(k), 15 U...

  6. CERN Technical Training 2006: LabVIEW Course Sessions (September-December 2006)

    CERN Multimedia

    2006-01-01

    The following LabVIEW course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2006, and in collaboration with National Instruments (CH): LabVIEW Basics 1 (course in English): 11-13.9.2006 (3 days, only 3 places available) LabVIEW Basics 2 (course in English): 14-15.9.2006 (2 days) LabVIEW: Working efficiently with LabVIEW 8 (course in English): 18.9.2006 (1 day) **NEW COURSE** LabVIEW Application Development (course in English): 13-15.11.2006 (3 days. Pre-requisite: LabVIEW Basics I ans II, or equivalent experience) LabVIEW Advanced Programming (course in English): 16-17.11.2006 (2 days. Pre-requisite: LabVIEW Application Development, or equivalent experience) LabVIEW Base 1 (course in French): 4-6.12.2006 (3 days, only 1 place available) LabVIEW Base 2 (course in French): 7-8.12.2006 (2 days) If you are interested in attending any of the above course sessions, please discuss with your supervisor and/or your DTO, and apply electronically via EDH from the cour...

  7. [22q11.2DS Syndrome as a Genetic Subtype of Schizophrenia].

    Science.gov (United States)

    Huertas-Rodríguez, Cindy Katherin; Payán-Gómez, César; Forero-Castro, Ruth Maribel

    2015-01-01

    The 22q11.2 deletion syndrome (22q11.2DS) is associated with the microdeletion of this chromosomal region, and represents the second most common genetic syndrome after Down's syndrome. In patients with schizophrenia, 22q11.2DS has a prevalence of 2%, and in selected groups can be increased to between 32-53%. To describe the generalities of 22q11.2DS syndrome as a genetic subtype of schizophrenia, its clinical characteristics, molecular genetic aspects, and frequency in different populations. A review was performed from 1967 to 2013 in scientific databases, compiling articles about 22q11.2DS syndrome and its association with schizophrenia. The 22q11.2 DS syndrome has a variable phenotype associated with other genetic syndromes, birth defects in many tissues and organs, and a high rate of psychiatric disorders, particularly schizophrenia. Likewise, it has been identified in clinical populations with schizophrenia selected by the presence of common syndromic characteristics. FISH, qPCR and MLPA techniques, and recently, aCGH and NGS technologies, are being used to diagnose this microdeletion. It is important in clinical practice to remember that people suffering the 22q11.2DS have a high genetic risk for developing schizophrenia, and it is considered that the simultaneous presence of this disease and 22q11.2DS represents a genetic subtype of schizophrenia. There are clear phenotypic criteria, molecular and cytogenetic methods to diagnose this group of patients, and to optimize a multidisciplinary approach in their monitoring. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  8. The comparison of deliveries in the center of Kahramanmaras in 2004 and 2006

    Directory of Open Access Journals (Sweden)

    Ayhan Coskun

    2007-09-01

    Full Text Available OBJECTIVE: To compare total delivery numbers and cesarean rates in Kahramanmaras city center during 2004 and 2006.\tDesign: Delivery records have been reviewed retrospectively.\tSetting: All hospitals in Kahramanmaras city center.\tPatients: Delivered pregnants. Interventions: None.\tMain Outcome Measures: Demographic characteritics, delivery routes of the pregnants and newborn birthweights. RESULTS: Cesarean section was performed in 3994 out of the 11611 deliveries (34.4 % in 2004 and 5573 out of the 13684 deliveries (40.2 % in 2006. There was an increase in both delivery number and cesarean rates in 2006 when compared with 2004. Delivery rates were increased from 10.3 % and 8.8 % in 2004 to 17.7 % and 12.9 % in 2006 for high risk groups like under 20 and above 35 year-old pregnants, respectively. Also, premature neonates below 2500 and macrosomic babies above 4000 g were increased in 2006 when compared with 2004. It may be thought that, an increase in delivery numbers, high risk pregnancies and cesarean rates could be inevitably cause a higher delivery complication ratios as years run.\tCONCLUSIONS: Obstetrician should be careful before a cesarean decision because previous cesarean is leading cesarean indication.

  9. Decision making by patients: An application of naturalistic decision making theory to cervical screening and chronic renal failure, Working Paper 2006/5

    OpenAIRE

    Marion Haas

    2006-01-01

    Over their lifetime, individuals typically make many decisions about health and health care. Theoretical approaches to decision making have been dominated by a rational, analytic approach which assumes that problems are relatively fixed and well-defined and which have foreseeable and measurable endpoints. Naturalistic decision making (NDM) approaches attempt to mimic ?real world? situations where problems vary, may be defined differently by individuals with diverse perspectives and where endp...

  10. Mapping 22q11.2 Gene Dosage Effects on Brain Morphometry.

    Science.gov (United States)

    Lin, Amy; Ching, Christopher R K; Vajdi, Ariana; Sun, Daqiang; Jonas, Rachel K; Jalbrzikowski, Maria; Kushan-Wells, Leila; Pacheco Hansen, Laura; Krikorian, Emma; Gutman, Boris; Dokoru, Deepika; Helleman, Gerhard; Thompson, Paul M; Bearden, Carrie E

    2017-06-28

    Reciprocal chromosomal rearrangements at the 22q11.2 locus are associated with elevated risk of neurodevelopmental disorders. The 22q11.2 deletion confers the highest known genetic risk for schizophrenia, but a duplication in the same region is strongly associated with autism and is less common in schizophrenia cases than in the general population. Here we conducted the first study of 22q11.2 gene dosage effects on brain structure in a sample of 143 human subjects: 66 with 22q11.2 deletions (22q-del; 32 males), 21 with 22q11.2 duplications (22q-dup; 14 males), and 56 age- and sex-matched controls (31 males). 22q11.2 gene dosage varied positively with intracranial volume, gray and white matter volume, and cortical surface area (deletion control > duplication). Widespread differences were observed for cortical surface area with more localized effects on cortical thickness. These diametric patterns extended into subcortical regions: 22q-dup carriers had a significantly larger right hippocampus, on average, but lower right caudate and corpus callosum volume, relative to 22q-del carriers. Novel subcortical shape analysis revealed greater radial distance (thickness) of the right amygdala and left thalamus, and localized increases and decreases in subregions of the caudate, putamen, and hippocampus in 22q-dup relative to 22q-del carriers. This study provides the first evidence that 22q11.2 is a genomic region associated with gene-dose-dependent brain phenotypes. Pervasive effects on cortical surface area imply that this copy number variant affects brain structure early in the course of development. SIGNIFICANCE STATEMENT Probing naturally occurring reciprocal copy number variation in the genome may help us understand mechanisms underlying deviations from typical brain and cognitive development. The 22q11.2 genomic region is particularly susceptible to chromosomal rearrangements and contains many genes crucial for neuronal development and migration. Not surprisingly

  11. 7 CFR 1220.112 - Industry information.

    Science.gov (United States)

    2010-01-01

    ... markets, new marketing strategies, or increased efficiency for the soybean industry, and activities to... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... CONSUMER INFORMATION Soybean Promotion and Research Order Definitions § 1220.112 Industry information. The...

  12. 48 CFR 870.112 - Telecommunications equipment.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Telecommunications... DEPARTMENT SUPPLEMENTARY REGULATIONS SPECIAL PROCUREMENT CONTROLS Controls 870.112 Telecommunications... specifications for telecommunications equipment, as defined in VA manual MP-6, Part VIII (available at any VA...

  13. Deleção 22q11.2 em pacientes com defeito cardíaco conotruncal e fenótipo da síndrome da deleção 22q11.2 Deleción 22q11.2 en pacientes con defecto cardiaco conotruncal y fenotipo del síndrome de la deleción 22q11.2 22q11.2 deletion in patients with conotruncal heart defect and del22q syndrome phenotype

    Directory of Open Access Journals (Sweden)

    Sintia Iole Nogueira Belangero

    2009-04-01

    Full Text Available FUNDAMENTO: A síndrome da deleção 22q11.2 é a mais freqüente síndrome de microdeleção humana. O fenótipo é altamente variável e caracterizado por defeito cardíaco conotruncal, dismorfias faciais, insuficiência velofaríngea, dificuldade de aprendizagem e retardo mental. OBJETIVO: O objetivo deste trabalho foi investigar a freqüência da deleção 22q11.2 em uma amostra brasileira de indivíduos portadores de cardiopatia conontrucal isolada e do fenótipo da síndrome da deleção 22q11.2. MÉTODOS: Vinte e nove pacientes foram estudados por meio de citogenética clássica, por hibridação in situ fluorescente (FISH e por técnicas moleculares. RESULTADOS: A análise citogenética por meio de bandamento G revelou cariótipo normal em todos os pacientes, com exceção de um que apresentou cariótipo 47,XX,+idic(22(q11.2. Com o uso de técnicas moleculares, a deleção foi observada em 25% dos pacientes, todos portadores do fenótipo da síndrome da deleção 22q11.2. Em nenhum dos casos, a deleção foi herdada dos pais. A freqüência da deleção 22q11.2 foi maior no grupo de pacientes portadores do espectro clínico da síndrome da deleção 22q11.2 do que no grupo de pacientes com cardiopatia conotruncal isolada. CONCLUSÃO: A investigação da presença da deleção e sua correlação com os dados clínicos dos pacientes podem auxiliar os pacientes e suas famílias a terem um melhor aconselhamento genético e um seguimento clínico mais adequado.FUNDAMENTO: El síndrome de la deleción 22q11.2 es el más frecuente síndrome de microdeleción humana. El fenotipo, altamente variable, se caracteriza por defecto cardiaco conotruncal, dismorfias faciales, insuficiencia velofaríngea, dificultad de aprendizaje y retardo mental. OBJETIVO: El objetivo de este trabajo fue investigar la frecuencia tanto de la deleción 22q11.2 en una muestra brasileña de individuos portadores de cardiopatía conotrucal aislada, como del fenotipo del s

  14. Europython 2006

    CERN Multimedia

    2006-01-01

    Europython 2006 - Annual Python Developer Conference, 3-5 July 2006, CERN Software developers from around the world will gather July 3-5 in Geneva, Switzerland for EuroPython 2006, the fifth annual conference for the Python programming language. The event is hosted this year at CERN, the birthplace of the Web, and promises an exciting slate of keynotes and talks. 'Python keeps growing each year, and EuroPython keeps getting better as well,' says Benedikt Hegner, host and one of the lead organizers for EuroPython 2006. 'This year saw Guido van Rossum, Python's creator, moving to Google with other key Python developers. Hosting EuroPython at CERN is a prestigious step for EuroPython as well. EuroPython 2006 will be keynoted both by Mr. van Rossum as well as Dr. Alan Kay, an originator of object-oriented programming and pioneer of graphical computing. The schedule has 3 days of talks in 8 tracks covering agile development, business, teaching, games, an expanded web frameworks track, and more. The organize...

  15. Balancing Information Analysis and Decision Value: A Model to Exploit the Decision Process

    Science.gov (United States)

    2011-12-01

    technical intelli- gence e.g. signals and sensors (SIGINT and MASINT), imagery (!MINT), as well and human and open source intelligence (HUMINT and OSINT ...Clark 2006). The ability to capture large amounts of da- ta and the plenitude of modem intelligence information sources provides a rich cache of...many tech- niques for managing information collected and derived from these sources , the exploitation of intelligence assets for decision-making

  16. CERN Technical Training 2006: LabVIEW Course Sessions (September-December 2006)

    CERN Multimedia

    2006-01-01

    The following LabVIEW course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2006, and in collaboration with National Instruments (CH): LabVIEW Basics 1 (course in English): 11-13.9.2006 (3 days, only 3 places available) (course in English): 14-15.9.2006 (2 days) LabVIEW: Working efficiently with LabVIEW 8 (course in English): 18.9.2006 (1 day) **NEW COURSE** LabVIEW Application Development (course in English): 13-15.11.2006 (3 days. Pre-requisite: LabVIEW Basics I ans II, or equivalent experience) LabVIEW Advanced Programming (course in English): 16-17.11.2006 (2 days. Pre-requisite: LabVIEW Application Development, or equivalent experience) LabVIEW Base 1 (course in French): 4-6.12.2006 (3 days, only 1 place available) LabVIEW Base 2 (course in French): 7-8.12.2006 (2 days) If you are interested in attending any of the above course sessions, please discuss with your supervisor and/or your DTO,...

  17. Referential communication abilities in children with 22q11.2 deletion syndrome.

    Science.gov (United States)

    Van Den Heuvel, Ellen; ReuterskiöLd, Christina; Solot, Cynthia; Manders, Eric; Swillen, Ann; Zink, Inge

    2017-10-01

    This study describes the performance on a perspective- and role-taking task in 27 children, ages 6-13 years, with 22q11.2 deletion syndrome (22q11.2DS). A cross-cultural design comparing Dutch- and English-speaking children with 22q11.2DS explored the possibility of cultural differences. Chronologically age-matched and younger typically developing (TD) children matched for receptive vocabulary served as control groups to identify challenges in referential communication. The utterances of children with 22q11.2DS were characterised as short and simple in lexical and grammatical terms. However, from a language use perspective, their utterances were verbose, ambiguous and irrelevant given the pictured scenes. They tended to elaborate on visual details and conveyed off-topic, extraneous information when participating in a barrier-game procedure. Both types of aberrant utterances forced a listener to consistently infer the intended message. Moreover, children with 22q11.2DS demonstrated difficulty selecting correct speech acts in accordance with contextual cues during a role-taking task. Both English- and Dutch-speaking children with 22q11.2DS showed impoverished information transfer and an increased number of elaborations, suggesting a cross-cultural syndrome-specific feature.

  18. Race, ethnicity, and shared decision making for hyperlipidemia and hypertension treatment: the DECISIONS survey.

    Science.gov (United States)

    Ratanawongsa, Neda; Zikmund-Fisher, Brian J; Couper, Mick P; Van Hoewyk, John; Powe, Neil R

    2010-01-01

    Racial/ethnic differences in shared decision making about cardiovascular risk-reduction therapy could affect health disparities. To investigate whether patient race/ethnicity is associated with experiences discussing cardiovascular risk-reduction therapy with health care providers. National sample of US adults identified by random-digit dialing. Cross-sectional survey conducted in November 2006 to May 2007. Among participants in the National Survey of Medical Decisions (DECISIONS), a nationally representative sample of English-speaking US adults aged 40 and older, the authors analyzed respondents who reported discussing hyperlipidemia or hypertension medications with a health care provider in the previous 2 years. In multivariate linear and logistic regressions adjusting for age, gender, income, insurance status, perceived health, and current therapy, they assessed the relation between race/ethnicity (black/Hispanic v. white) and decision making: knowledge, discussion of pros and cons of therapy, discussion of patient preference, who made the final decision, preferred involvement, and confidence in the decision. Of respondents who discussed high cholesterol (N = 738) or hypertension (N = 745) medications, 88% were white, 9% black, and 4% Hispanic. Minorities had lower knowledge scores than whites for hyperlipidemia (42% v. 52%, difference -10% [95% confidence interval (CI): 15, -5], P decision-making process.

  19. Bibliographie 2006-2007

    Directory of Open Access Journals (Sweden)

    Florence Klein

    2007-12-01

    Full Text Available 1. Histoire, genres et théories littérairesArrighetti, G. (2006, Poesia, poetiche e storia nella riflessione dei greci. Studi, Giardini, Pisa (Biblioteca di studi antichi 89.Asmis, E. (2006 « Epicurean poetics » in A. Laird (éd., Ancient literary criticism. (Oxford Readings in Classical Studies. Oxford : Oxford UP, p. 238-266.Ax, W. (2006 Text und Stil. Studien zur antiken Literatur und deren Rezeption ; Stuttgart, Steiner. Batstone, W. W. (2006 « Provocation : The Point of Reception T...

  20. The Wing Beat of the Butterfly. The Causality of Asymmetric Cultural Encounters and Escalation in Babel (2006 and Valley of Wolves – Iraq/ Kurtlar Vadisi – Irak (2006

    Directory of Open Access Journals (Sweden)

    Veronika Bernard

    2011-10-01

    Full Text Available The term ‘asymmetric conflict’ describes a war-like situation in which the opponents involved do not have equal access to decisive logistic resources. The author of this article states that cultural en­coun­ters can also be of asymmetric quality: in situations of provoked or accidental (intercultural mis­understandings, in hierarchical situations and in cases of emergency. She further states that the mo­vies Babel (2006 and Valley of Wolves – Iraq (2006 can be seen as cinematic adaptations of such cases putting the focus on the causality of asymmetric cultural encounters and escalation. The ar­tic­le deals with the major cinematic tools applied in visualizing this causality in the two films.

  1. 23 CFR 660.112 - Project development.

    Science.gov (United States)

    2010-04-01

    ... PROGRAMS (DIRECT FEDERAL) Forest Highways § 660.112 Project development. (a) Projects to be administered by... Program. Projects to be administered by a cooperator shall be developed in accordance with Federal-aid procedures and procedures documented in the statewide agreement. (b) The FH projects shall be designed in...

  2. Moving toward focal therapy in prostate cancer: dual-isotope permanent seed implants as a possible solution.

    Science.gov (United States)

    Todor, Dorin A; Barani, Igor J; Lin, Peck-Sun; Anscher, Mitchell S

    2011-09-01

    To compare the ability of single- and dual-isotope prostate seed implants to escalate biologically effective dose (BED) to foci of disease while reducing prescription dose to the prostate. Nine plans, using 125I, 103Pd, and 131Cs alone and in combination were created retrospectively for 2 patients. Ultrasound and MRI/MRS datasets were used for treatment planning. Voxel-by-voxel BED was calculated for single- and dual-isotope plans. Equivalent uniform BED (EUBED) was used to compare plans. The MRS-positive planning target volumes (PTVi) were delineated along with PTV (prostate+5 mm), rectum, and urethra. Single-isotope implants, prescribed to conventional doses, were generated to achieve good PTV coverage. The PTVi were prospectively used to generate implants using mixtures of isotopes. For mixed-radioisotope implants, we also explored the impact on EUBED of lowering prescription doses by 15%. The EUBED of PTVi in the setting of primary 125I implant increased 20-66% when 103Pd and 131Cs were used compared with 125I boost. Decreasing prescription dose by 15% in mixed-isotope implants results in a potential 10% reduction in urethral EUBED with preservation of PTV coverage while still boosting PTVi (up to 80%). When radiobiologic parameters corresponding to more-aggressive disease are assigned to foci, faster-decaying isotopes used in mixed implants have the potential to preserve the equivalent biological effect of mono-isotope implants considering less-aggressive disease distributed in the entire prostate. This is a hypothesis-generating study proposing a treatment paradigm that could be the middle ground between whole-gland irradiation and focal-only treatment. The use of two isotopes concurrent with decreasing the minimal peripheral dose is shown to increase EUBED of selected subvolumes while preserving the therapeutic effect at the level of the gland. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Core drilling of short drillholes at Olkiluoto in Eurajoki 2006

    International Nuclear Information System (INIS)

    Rautio, T.

    2007-05-01

    Posiva Oy submitted an application to the Finnish Government in May 1999 for the Decision in Principle to choose Olkiluoto in the municipality of Eurajoki as the site of the final disposal facility for spent nuclear fuel. A positive decision was made at the end of 2000 by the Government. The Finnish Parliament ratified the decision in May 2001. The decision makes it possible for Posiva to focus the confirming bedrock investigations at Olkiluoto, where in the next few years an underground rock characterisation facility, ONKALO, will be constructed. As a part of the investigations Suomen Malmi Oy (Smoy) core drilled six short drillholes with a diameter of 75.7 mm at Olkiluoto in July - August 2006. The identification numbers of the drillholes are OL-PP51 - OL-PP56. The deviation of the drillholes was measured with the deviation measuring instruments Reflex EMS. A set of monitoring measurements and samplings from the drilling and returning water was carried out during the drilling. The volume of the drilling water was recorded. Sodium fluorescein was used as a label agent in the drilling water. The total volume of the used drilling and flushing water were 37 m 3 . (orig.)

  4. 9 CFR 112.2 - Final container label, carton label, and enclosure.

    Science.gov (United States)

    2010-01-01

    ... carton; (10) In the case of a product which contains an antibiotic added during the production process... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Final container label, carton label, and enclosure. 112.2 Section 112.2 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION...

  5. 46 CFR 112.01-10 - Automatic emergency lighting and power system.

    Science.gov (United States)

    2010-10-01

    ... EMERGENCY LIGHTING AND POWER SYSTEMS Definitions of Emergency Lighting and Power Systems § 112.01-10 Automatic emergency lighting and power system. An automatic emergency lighting and power system is one in... 46 Shipping 4 2010-10-01 2010-10-01 false Automatic emergency lighting and power system. 112.01-10...

  6. RECENT REFERENCES: JULY 1, 2006 TO SEPTEMBER 30, 2006

    Energy Technology Data Exchange (ETDEWEB)

    WINCHELL, D.F.

    2006-09-30

    This document lists experimental references added to Nuclear Science References (NSR) during the period July 1, 2006 to September 30, 2006. The first section lists keynumbers and keywords sorted by mass and nuclide. The second section lists all references, ordered by keynumber.

  7. Meie tipud 2006 : ¡Eesti kirjanduskriitika artikliauhinnast 2006. aastal / Linnar Priimägi

    Index Scriptorium Estoniae

    Priimägi, Linnar, 1954-

    2007-01-01

    Eesti kirjanduskriitika 2006. aasta artikliauhinna neljast nominendist Anne Lillest (Antiiktragöödia, esteetika paradoksid ja Mati Unt. Keel ja Kirjandus 2006, nr. 6), Toomas Haugist (A. H. T. surm Aafrikas. Lisandusi Leo Frobeniuse "Jumala külalise" kadunud tõlkele. Looming 2006, nr. 6), Märt Väljatagast (Orja teadvus varjus ja valguses. Looming 2006, nr. 12) ja Eneken Laanesest (Mäletamise lühis: Ene Mihkelsoni "Ahasveeruse uni". Keel ja Kirjandus 2006, nr. 6)

  8. 24 CFR 1000.112 - How will HUD determine whether to approve model housing activities?

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false How will HUD determine whether to approve model housing activities? 1000.112 Section 1000.112 Housing and Urban Development Regulations... Activities § 1000.112 How will HUD determine whether to approve model housing activities? HUD will review all...

  9. Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome.

    Science.gov (United States)

    Larsen, Kit Melissa; Mørup, Morten; Birknow, Michelle Rosgaard; Fischer, Elvira; Hulme, Oliver; Vangkilde, Anders; Schmock, Henriette; Baaré, William Frans Christiaan; Didriksen, Michael; Olsen, Line; Werge, Thomas; Siebner, Hartwig R; Garrido, Marta I

    2018-01-30

    22q11.2 deletion syndrome (22q11.2DS) is one of the most common copy number variants and confers a markedly increased risk for schizophrenia. As such, 22q11.2DS is a homogeneous genetic liability model which enables studies to delineate functional abnormalities that may precede disease onset. Mismatch negativity (MMN), a brain marker of change detection, is reduced in people with schizophrenia compared to healthy controls. Using dynamic causal modelling (DCM), previous studies showed that top-down effective connectivity linking the frontal and temporal cortex is reduced in schizophrenia relative to healthy controls in MMN tasks. In the search for early risk-markers for schizophrenia we investigated the neural basis of change detection in a group with 22q11.2DS. We recorded high-density EEG from 19 young non-psychotic 22q11.2 deletion carriers, as well as from 27 healthy non-carriers with comparable age distribution and sex ratio, while they listened to a sequence of sounds arranged in a roving oddball paradigm. Despite finding no significant reduction in the MMN responses, whole-scalp spatiotemporal analysis of responses to the tones revealed a greater fronto-temporal N1 component in the 22q11.2 deletion carriers. DCM showed reduced intrinsic connection within right primary auditory cortex as well as in the top-down, connection from the right inferior frontal gyrus to right superior temporal gyrus for 22q11.2 deletion carriers although not surviving correction for multiple comparison. We discuss these findings in terms of reduced adaptation and a general increased sensitivity to tones in 22q11.2DS. Copyright © 2018. Published by Elsevier B.V.

  10. Attention Deficit Hyperactivity Disorder Symptoms and Psychosis in 22q11.2 Deletion Syndrome.

    Science.gov (United States)

    Niarchou, Maria; Calkins, Monica E; Moore, Tyler M; Tang, Sunny X; McDonald-McGinn, Donna M; Zackai, Elaine H; Emanuel, Beverly S; Gur, Ruben C; Gur, Raquel E

    2017-10-10

    22q11.2 Deletion Syndrome (22q11.2DS) is associated with increased risk for schizophrenia in adulthood while Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent diagnosis in childhood. Inattention symptoms are pronounced in 22q11.2DS and given that attentional impairment is a core feature of schizophrenia, inattention symptoms may reflect underlying ADHD, psychosis, or both. We investigate whether inattention is associated with psychosis in 22q11.2DS and in other groups at risk for psychosis but without the deletion (ND) (idiopathic clinical risk and first degree family members of individuals with schizophrenia). One hundred thirty-seven individuals with 22q11.2DS (mean age: 14.0), 84 ND individuals with subthreshold psychosis (mean age: 16.9) and 31 ND individuals with family history of psychosis (mean age: 17.0) were included in the study. Psychopathology was assessed using research diagnostic assessments. ADHD total symptoms were associated with overall levels of subthreshold psychosis symptoms in 22q11.2DS (β = .8, P = .04). Inattention symptoms were specifically associated with positive (β = .5, P = .004), negative (β = .5, P = .03), and disorganized (β = .5, P hyperactivity-impulsivity symptoms were associated with disorganized symptoms (β = .5, P = .01). The prevalence of ADHD inattention symptoms was higher in 22q11.2DS with subthreshold psychosis compared to ND individuals with subthreshold psychosis (P < .001), even when adjusting for cognitive impairment and overall psychopathology. The pattern was similar when comparing individuals with 22q11.2DS and ND individuals with family history of psychosis. This is the first study to examine the associations between ADHD symptoms and psychosis in 22q11.2DS. Our findings support a potentially important role of ADHD inattention symptoms in psychosis in 22q11.2DS. © The Author 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights

  11. Search of the decay of the heaviest isotopes of element 112

    International Nuclear Information System (INIS)

    Oganesyan, Yu.Ts.; Eremin, A.V.; Gul'bekyan, G.G.

    1998-01-01

    To produce heavy isotopes of element 112 in the reaction 48 Ca + 238 U two experiments at different beam energies were performed. In the first experiment the beam energy at the middle of the target was 231 MeV which leads to the production of the compound nucleus 286 112 with an excitation energy of E x = 33 MeV. In a 20 - day irradiation of the 238 U target with a beam dose of 3.5 x 10 18 on the focal plane of the recoil separator VASSILISSA two spontaneous fission events were detected. No α-particle emission preceding spontaneous fission nor α-α correlation in the energy range from 8 to 13 MeV in the time interval of up to 10000 s. have been observed. The most probable explanation of the data obtained in this experiment is that the observed spontaneous fission corresponds to the decay of the even-odd isotope (N = 171) of element 112 produced in the reaction 238 U ( 48 Ca, 3n) 283 112 with a cross section of ∼ 5 pb. The half-life of the new spontaneous fission nuclide is about 100 s. In the second experiment the beam energy was 238 MeV which increases the excitation energy of compound nuclei up to E x = 39 MeV. The total beam dose in that case was 2.2 x 10 18 . No events due either to spontaneous fission or sequential α-α decay in an energy range from 8 to 12 MeV and the time interval of 1000 s. were detected. These data give the upper limit of 3 pb for the production cross section of the even-even isotope 282 112 in the reaction 238 U ( 48 Ca, 4n) 282 112

  12. 12 CFR 221.112 - Loans by bank in capacity as trustee.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Loans by bank in capacity as trustee. 221.112... CARRYING MARGIN STOCK (REGULATION U) Interpretations § 221.112 Loans by bank in capacity as trustee. (a... been pledged as collateral for loans. Loans are not made, under the plan, from bank funds, and...

  13. 46 CFR 112.01-5 - Manual emergency lighting and power system.

    Science.gov (United States)

    2010-10-01

    ... EMERGENCY LIGHTING AND POWER SYSTEMS Definitions of Emergency Lighting and Power Systems § 112.01-5 Manual emergency lighting and power system. A manual emergency lighting and power system is one in which a single... 46 Shipping 4 2010-10-01 2010-10-01 false Manual emergency lighting and power system. 112.01-5...

  14. 7 CFR 920.112 - Late payments.

    Science.gov (United States)

    2010-01-01

    ... Miscellaneous Provisions § 920.112 Late payments. Pursuant to § 920.41(a), interest will be charged at a 1.5 percent monthly simple interest rate. Assessments for kiwifruit shall be deemed late if not received... late charge will be assessed when payment becomes 30 days late. Interest and late payment charges shall...

  15. Children with Chromosome 22q11.2 Deletion Syndrome Exhibit Impaired Spatial Working Memory

    Science.gov (United States)

    Wong, Ling M.; Riggins, Tracy; Harvey, Danielle; Cabaral, Margarita; Simon, Tony J.

    2014-01-01

    Individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS) have been shown to have impairments in processing spatiotemporal information. The authors examined whether children with 22q11.2DS exhibit impairments in spatial working memory performance due to these weaknesses, even when controlling for maintenance of attention. Children with…

  16. MN112: a new Galactic candidate luminous blue variable

    Science.gov (United States)

    Gvaramadze, V. V.; Kniazev, A. Y.; Fabrika, S.; Sholukhova, O.; Berdnikov, L. N.; Cherepashchuk, A. M.; Zharova, A. V.

    2010-06-01

    We report the discovery of a new Galactic candidate luminous blue variable (cLBV) via detection of an infrared circular nebula and follow-up spectroscopy of its central star. The nebula, MN112, is one of many dozens of circular nebulae detected at 24μm in the Spitzer Space Telescope archival data, whose morphology is similar to that of nebulae associated with known (c)LBVs and related evolved massive stars. Specifically, the core-halo morphology of MN112 bears a striking resemblance to the circumstellar nebula associated with the Galactic cLBV GAL079.29+00.46, which suggests that both nebulae might have a similar origin and that the central star of MN112 is an LBV. The spectroscopy of the central star showed that its spectrum is almost identical to that of the bona fide LBV PCygni, which also supports the LBV classification of the object. To further constrain the nature of MN112, we searched for signatures of possible high-amplitude (>~1mag) photometric variability of the central star using archival and newly obtained photometric data covering a 45-yr period. We found that the B magnitude of the star was constant within error margins, while in the I band the star brightened by ~=0.4mag during the last 17 yr. Although the non-detection of large photometric variability leads us to use the prefix `candidate' in the classification of MN112, we remind the readers that the long-term photometric stability is not unusual for genuine LBVs and that the brightness of PCygni remained relatively stable during the last three centuries. Partially based on observations collected at the German-Spanish Astronomical Center, Calar Alto, jointly operated by the Max-Planck-Institut für Astronomie Heidelberg and the Instituto de Astrofísica de Andalucía (CSIC). E-mail: vgvaram@mx.iki.rssi.ru (VVG); akniazev@saao.ac.za (AYK); fabrika@sao.ru (SF); olga@sao.ru (OS); berdnik@sai.msu.ru (LNB); cher@sai.msu.ru (AMC); alla@sai.msu.ru (AVZ)

  17. Chemical identification and properties of element 112

    Czech Academy of Sciences Publication Activity Database

    Yakushev, AB.; Zvára, Ivo; Oganessian, YT.; Belozerov, AV.; Dmitriev, S. N.; Eichler, B.; Hubener, S.; Sokol, EA.; Turler, A.; Yeremin, AV.; Buklanov, GV.; Chelnokov, ML.; Chepigin, VI.; Gorshkov, VA.; Gulyaev, AV.; Lebedev, VY.; Malyshev, ON.; Popeko, AG.; Soverna, S.; Szeglowski, Z.; Timokhin, SN.; Tretyakova, SP.; Vasko, VM.; Itkis, MG.

    2003-01-01

    Roč. 91, č. 8 (2003), s. 433-439 ISSN 0033-8230 Institutional research plan: CEZ:AV0Z1048901 Keywords : element 112 * superheavy elements * transactinoids Subject RIV: CH - Nuclear ; Quantum Chemistry Impact factor: 0.940, year: 2003

  18. Decision-making in Sport under Mental and Physical Stress

    Directory of Open Access Journals (Sweden)

    Teri J. Hepler

    2015-10-01

    Full Text Available Background: Successful decision-making in sport requires good decisions to be made quickly, but little is understood about the decision process under stress. Objective: The purpose of this study was to compare decision outcomes and the Take the First (TTF heuristic under conditions of mental, physical, and no stress.  Method:  Participants (N=112 were divided into 3 stress groups:  mental stress (mental serial subtraction, physical stress (running on treadmill at 60-70% of maximum effort, and no stress (counting backwards by 1. Participants were exposed to 30 seconds of stress and then watched a video depicting an offensive situation in basketball requiring them to decide what the player with the ball should do next. Each participant performed 10 trials of the video decision-making task.  Results: No differences were found between the 3 stress groups on decision quality, TTF frequency, number of options generated, or quality of first generated option.  However, participants in the no stress and physical stress conditions were faster in generating their first option and making their final decision as compared to the mental stress group.  Conclusion: Overall, results suggest that mental stress impairs decision speed and that TTF is an ecologically rationale heuristic in dynamic, time-pressured situations.  Keywords: Take the first, Heuristic, Pressure, Cognitive performance

  19. 47 CFR 68.112 - Hearing aid-compatibility.

    Science.gov (United States)

    2010-10-01

    .... Note: Examples of workplace non-common areas include private enclosed offices, open area individual....112 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED... workplace common areas. Note to paragraph (b)(1): Examples of workplace common areas include libraries...

  20. Scientific days of Marcoule 2006; Journees scientifiques Marcoule 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The sixth scientific days of Marcoule 2006 took place in La Grande Motte, on 15-19 May 2006. During these days, the research works of the PhD students of Marcoule and Pierrelatte centers are presented. A summary of the progress of each PhD thesis is given below. (O.M.)

  1. Areva in 2006

    International Nuclear Information System (INIS)

    2007-01-01

    This document is the 2006 activity report of the Areva group and presents the 2006 highlights of the nuclear division (front end of the nuclear cycle, pressurized water reactors, treatment and recycling of used nuclear fuel) and of the Transmission and Distribution division. Content: Message from the Chairman of the Supervisory Board; Message from the Chief Executive Officer; the World in 2006; Areva 2006 highlights; business review; key data; Areva around the World; policy of continuous innovation; five years of sustainable development; governance; Continuous improvement; Financial performance; Innovation; Customer satisfaction; Commitment to employees; Environmental protection; Risk management and prevention; Dialogue and consensus building; Community involvement; corporate governance; organization of the group; Share information and shareholder relations; glossary; learn more

  2. Developmental changes in decision making under risk: The role of executive functions and reasoning abilities in 8- to 19-year-old decision makers.

    Science.gov (United States)

    Schiebener, Johannes; García-Arias, María; García-Villamisar, Domingo; Cabanyes-Truffino, Javier; Brand, Matthias

    2015-01-01

    Previous studies have shown that children and adolescents often tend toward risky decisions despite explicit knowledge about the potential negative consequences. This phenomenon has been suggested to be associated with the immaturity of brain areas involved in cognitive control functions. Particularly, "frontal lobe functions," such as executive functions and reasoning, mature until young adulthood and are thought to be involved in age-related changes in decision making under explicit risk conditions. We investigated 112 participants, aged 8-19 years, with a frequently used task assessing decisions under risk, the Game of Dice Task (GDT). Additionally, we administered the Modified Card Sorting Test assessing executive functioning (categorization, cognitive flexibility, and strategy maintenance) as well as the Ravens Progressive Matrices assessing reasoning. The results showed that risk taking in the GDT decreased with increasing age and this effect was not moderated by reasoning but by executive functions: Particularly, young persons with weak executive functioning showed very risky decision making. Thus, the individual maturation of executive functions, associated with areas in the prefrontal cortex, seems to be an important factor in young peoples' behavior in risky decision-making situations.

  3. Examining the Overlap between Autism Spectrum Disorder and 22q11.2 Deletion Syndrome.

    Science.gov (United States)

    Ousley, Opal; Evans, A Nichole; Fernandez-Carriba, Samuel; Smearman, Erica L; Rockers, Kimberly; Morrier, Michael J; Evans, David W; Coleman, Karlene; Cubells, Joseph

    2017-05-18

    22q11.2 deletion syndrome (22q11.2DS) is a genomic disorder reported to associate with autism spectrum disorders (ASDs) in 15-50% of cases; however, others suggest that individuals with 22q11.2DS present psychiatric or behavioral features associated with ASDs, but do not meet full criteria for ASD diagnoses. Such wide variability in findings may arise in part due to methodological differences across studies. Our study sought to determine whether individuals with 22q11.2DS meet strict ASD diagnostic criteria using research-based guidelines from the Collaborative Programs of Excellence in Autism (CPEA), which required a gathering of information from three sources: the Autism Diagnostic Interview-Revised (ADI-R), the Autism Diagnostic Observational Schedule (ADOS), and a clinician's best-estimate diagnosis. Our study examined a cohort of children, adolescents, and young adults ( n = 56) with 22q11.2DS, who were ascertained irrespective of parents' behavioral or developmental concerns, and found that 17.9% ( n = 10) of the participants met CPEA criteria for an ASD diagnosis, and that a majority showed some level of social-communication impairment or the presence of repetitive behaviors. We conclude that strictly defined ASDs occur in a substantial proportion of individuals with 22q11.2DS, and recommend that all individuals with 22q11.2DS be screened for ASDs during early childhood.

  4. Building relationships with Aboriginal Communities and the Energy and Utilities Board

    Energy Technology Data Exchange (ETDEWEB)

    Barber, R.; Handel, J.; Healy, D. [Alberta Energy and Utilities Board, Calgary, AB (Canada)

    2004-07-01

    One of the challenges facing the oil and gas industry in Alberta is building a relationship between industry, government and Aboriginal people. The Alberta Energy and Utilities Board (EUB) is promoting and developing positive relationships with Aboriginal communities in terms of land-use issues and land claim agreements. A study was commissioned in 2000 by the EUB to identify concerns to communities affected by sour gas development. The study identified the need to improve working relations with Aboriginal communities. This paper describes the experience of the Field Surveillance Branch of the EUB over the past few years in building such relationships. Historical information provides insight that helps in establishing effective working relationships with Aboriginal communities. An important ingredient is appreciation of the perspective of these communities, which is achieved through awareness training. The use of local Aboriginal resource people as part of the training is recommended in order to address local issues. 1 ref.

  5. Discovery of element 112

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, S. [GSI, Darmstadt (Germany)

    1996-12-31

    The new elements 110, 111, and 112 were synthesized and unambiguously identified in experiments at SHIP. Due to strong shell effects the dominant decay mode is not fission, but emission of alpha particles. Theoretical investigations predict that maximum shell effects should exist in nuclei near proton number 114 and neutron number 184. Measurements give hope that isotopes of element 114 close to the island of spherical Superheavy Elements could be produced by fusion reactions using {sup 118}Pb as target. systematic studies of the reaction cross-sections indicate that transfer of nucleons is the important process to initiate the fusion.

  6. Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements

    NARCIS (Netherlands)

    Demaerel, Wolfram; Hestand, Matthew S.; Vergaelen, Elfi; Swillen, Ann; López-Sánchez, Marcos; Pérez-Jurado, Luis A.; McDonald-Mcginn, Donna M.; Zackai, Elaine; Emanuel, Beverly S.; Morrow, Bernice E.; Breckpot, Jeroen; Devriendt, Koenraad; Vermeesch, Joris R.; Antshel, Kevin M.; Arango, Celso; Armando, Marco; Bassett, Anne S.; Bearden, Carrie E.; Boot, Erik; Bravo-Sanchez, Marta; Breetvelt, Elemi; Busa, Tiffany; Butcher, Nancy J.; Campbell, Linda E.; Carmel, Miri; Chow, Eva W C; Crowley, T. Blaine; Cubells, Joseph; Cutler, David; Demaerel, Wolfram; Digilio, Maria Cristina; Duijff, Sasja; Eliez, Stephan; Emanuel, Beverly S.; Epstein, Michael P.; Evers, Rens; Fernandez Garcia-Moya, Luis; Fiksinski, Ania; Fraguas, David; Fremont, Wanda; Fritsch, Rosemarie; Garcia-Minaur, Sixto; Golden, Aaron; Gothelf, Doron; Guo, Tingwei; Gur, Ruben C.; Gur, Raquel E.; Heine-Suner, Damian; Hestand, Matthew; Hooper, Stephen R.; Kates, Wendy R.; Kushan, Leila; Laorden-Nieto, Alejandra; Maeder, Johanna; Marino, Bruno; Marshall, Christian R.; McCabe, Kathryn; McDonald-Mcginn, Donna M.; Michaelovosky, Elena; Morrow, Bernice E.; Moss, Edward; Mulle, Jennifer; Murphy, Declan; Murphy, Kieran C.; Murphy, Clodagh M.; Niarchou, Maria; Ornstein, Claudia; Owen, Michael J; Philip, Nicole; Repetto, Gabriela M.; Schneider, Maude; Shashi, Vandana; Simon, Tony J.; Swillen, Ann; Tassone, Flora; Unolt, Marta; Van Amelsvoort, Therese; van den Bree, Marianne B M; Van Duin, Esther; Vergaelen, Elfi; Vermeesch, Joris R.; Vicari, Stefano; Vingerhoets, Claudia; Vorstman, Jacob; Warren, Steve; Weinberger, Ronnie; Weisman, Omri; Weizman, Abraham; Zackai, Elaine; Zhang, Zhengdong; Zwick, Michael

    2017-01-01

    Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no such inversions have

  7. Early onset intellectual disability in chromosome 22q11.2 deletion syndrome.

    Science.gov (United States)

    Cascella, Marco; Muzio, Maria Rosaria

    2015-01-01

    Chromosome 22q11.2 deletion syndrome, or DiGeorge syndrome, or velocardiofacial syndrome, is one of the most common multiple anomaly syndromes in humans. This syndrome is commonly caused by a microdelection from chromosome 22 at band q11.2. Although this genetic disorder may reflect several clinical abnormalities and different degrees of organ commitment, the clinical features that have driven the greatest amount of attention are behavioral and developmental features, because individuals with 22q11.2 deletion syndrome have a 30-fold risk of developing schizophrenia. There are differing opinions about the cognitive development, and commonly a cognitive decline rather than an early onset intellectual disability has been observed. We report a case of 22q11.2 deletion syndrome with both early assessment of mild intellectual disabilities and tetralogy of Fallot as the only physic manifestation. Copyright © 2015 Sociedad Chilena de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Ocular Findings in Children With 22q11.2 Deletion Syndrome.

    Science.gov (United States)

    Gokturk, Bahar; Topcu-Yilmaz, Pinar; Bozkurt, Banu; Yildirim, Mahmut Selman; Guner, Sukru Nail; Sayar, Esra Hazar; Reisli, Ismail

    2016-07-01

    To identify the ocular features of children diagnosed as having 22q11.2 deletion syndrome in a Turkish population, which is the most common microdeletion syndrome with a wide range of facial and ocular abnormalities. Sixteen children aged between 4 months and 18 years with a microdeletion in chromosome 22q11.2 underwent a detailed ophthalmological examination including uncorrected and best corrected visual acuity testing, stereoscopic vision examination, biomicroscopic and indirect fundus examination, and ocular motility testing. All patients had at least one ocular abnormality. The major abnormalities were eyelid abnormalities (eye hooding, narrow palpebral fissure, telecanthus, hypertelorism, sparse and thin eyebrows and eyelashes, blepharitis, and distichiasis), posterior embryotoxon, and tortuous retinal vessels in at least half of the patients. Other ophthalmological disorders were refractive errors, iris remnants, and strabismus. The chromosome 22q11.2 deletion syndrome is associated with a wide range of ocular disorders, which necessitates a comprehensive eye examination for appropriate treatment and follow-up. Ocular findings sometimes can provide a clue to the diagnosis of 22q11.2 deletion. [J Pediatr Ophthalmol Strabismus. 2016;53(4):218-222]. Copyright 2016, SLACK Incorporated.

  9. Temporal trends in non-occupational sedentary behaviours from Australian Time Use Surveys 1992, 1997 and 2006

    Directory of Open Access Journals (Sweden)

    Chau Josephine Y

    2012-06-01

    Full Text Available Abstract Background Current epidemiological data highlight the potential detrimental associations between sedentary behaviours and health outcomes, yet little is known about temporal trends in adult sedentary time. This study used time use data to examine population trends in sedentary behaviours in non-occupational domains and more specifically during leisure time. Methods We conducted secondary analysis of population representative data from the Australian Time Use Surveys 1992, 1997 and 2006 involving respondents aged 20 years and over with completed time use diaries for two days. Weighted samples for each survey year were: n = 5851 (1992, n = 6419 (1997 and n = 5505 (2006. We recoded all primary activities by domain (sleep, occupational, transport, leisure, household, education and intensity (sedentary, light, moderate. Adjusted multiple linear regressions tested for differences in time spent in non-occupational sedentary behaviours in 1992 and 1997 with 2006 as the reference year. Results Total non-occupational sedentary time was slightly lower in 1997 than in 2006 (mean = 894 min/2d and 906 min/2d, respectively; B = −11.2; 95%CI: -21.5, -0.9. Compared with 2006, less time was spent in 1997 in sedentary transport (B-6.7; 95%CI: -10.4, -3.0 and sedentary education (B = −6.3; 95%CI: -10.5, -2.2 while household and leisure sedentary time remained stable. Time engaged in different types of leisure-time sedentary activities changed between 1997 and 2006: leisure-time computer use increased (B = −26.7; 95%CI: -29.5, -23.8, while other leisure-time sedentary behaviours (e.g., reading, listening to music, hobbies and crafts showed small concurrent reductions. In 1992, leisure screen time was lower than in 2006: TV-viewing (B = −24.2; 95%CI: -31.2, -17.2, computer use (B = −35.3; 95%CI: -37.7, -32.8. In 2006, 90 % of leisure time was spent sedentary, of which 53 % was screen time. Conclusions Non

  10. Measurements for municipalities 2006

    NARCIS (Netherlands)

    B. Kuhry; J.J.J. Jonker; with cooperation of Bureau Zenc

    2006-01-01

    Original title: Maten voor gemeenten 2006. Measurements for municipalities 2006 (Maten voor gemeenten 2006) presents a national picture of the performance delivered by local authorities and the costs of doing so. The analyses relate to the period 1999-2004. This is the fourth time

  11. 7 CFR 1221.112 - Budget and expenses.

    Science.gov (United States)

    2010-01-01

    ... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... INFORMATION ORDER Sorghum Promotion, Research, and Information Order Sorghum Promotion, Research, and Information Board § 1221.112 Budget and expenses. (a) Prior to the beginning of each fiscal period, and as may...

  12. Examining the Overlap between Autism Spectrum Disorder and 22q11.2 Deletion Syndrome

    Directory of Open Access Journals (Sweden)

    Opal Ousley

    2017-05-01

    Full Text Available 22q11.2 deletion syndrome (22q11.2DS is a genomic disorder reported to associate with autism spectrum disorders (ASDs in 15–50% of cases; however, others suggest that individuals with 22q11.2DS present psychiatric or behavioral features associated with ASDs, but do not meet full criteria for ASD diagnoses. Such wide variability in findings may arise in part due to methodological differences across studies. Our study sought to determine whether individuals with 22q11.2DS meet strict ASD diagnostic criteria using research-based guidelines from the Collaborative Programs of Excellence in Autism (CPEA, which required a gathering of information from three sources: the Autism Diagnostic Interview-Revised (ADI-R, the Autism Diagnostic Observational Schedule (ADOS, and a clinician’s best-estimate diagnosis. Our study examined a cohort of children, adolescents, and young adults (n = 56 with 22q11.2DS, who were ascertained irrespective of parents’ behavioral or developmental concerns, and found that 17.9% (n = 10 of the participants met CPEA criteria for an ASD diagnosis, and that a majority showed some level of social-communication impairment or the presence of repetitive behaviors. We conclude that strictly defined ASDs occur in a substantial proportion of individuals with 22q11.2DS, and recommend that all individuals with 22q11.2DS be screened for ASDs during early childhood.

  13. Comparison of the 1999 and 2006 Trauma Triage Guidelines: Where do Patients Go?

    Science.gov (United States)

    Lerner, E. Brooke; Shah, Manish N.; Swor, Robert; Cushman, Jeremy T.; Guse, Clare E.; Brasel, Karen; Blatt, Alan; Jurkovich, Gregory J.

    2010-01-01

    In 2006, the CDC released a revised Field Triage Decision Scheme. It is unknown how this modified scheme will affect the number of patients identified by EMS for transport to a trauma center. Objective To determine the change in the number of patients transported by EMS who meet the 2006 scheme, compared to the 1999 scheme, and to determine how the scheme change would affect under- and over-triage rates. Methods EMS providers in charge of care for injured adult patients transported to a regional trauma center in three mid-sized cities were interviewed immediately after completing transport. All injured patients were included, regardless of severity. The interview included patient demographics, vital signs, apparent anatomic injury, and the mechanism of injury. Included patients were then followed through hospital discharge. The 1999 and 2006 scheme criteria were each retrospectively applied to the collected data. The number of patients identified by the two schemes was determined. Patients were considered to have needed a trauma center if they had non-orthopedic surgery within 24 hours, ICU admission, or died. Data were analyzed using descriptive statistics including 95% confidence intervals. Results EMS interviews were conducted for 11,892 patients and outcome data was unavailable for one patient. Average patient age was 48 years; 51% were men. Providers reported bringing 54% of the enrolled patients to the trauma center based on their local trauma protocol. 12% of enrolled patients were identified as needing a trauma center based on medical record review. Use of the 2006 scheme would have resulted in 1,423 fewer patients (12%; 95% CI:11-13%) being identified as needing a trauma center by EMS providers (40%; 95%CI:39-41% versus 28%; 95%CI:27-29%). 1,344 of those patients did not actually need the resources of a trauma center (94%). 78 (6%) of those patients actually needed the resources of a trauma center and would have been under-triaged. Conclusion Use of the

  14. A simple tool to help decision making in infrastructure planning and ...

    African Journals Online (AJOL)

    2006-10-04

    Oct 4, 2006 ... a tool to help decision making for planning and management of phytotreatment ... mental studies aimed at the quantitative estimation of biologi- cal processes .... water has been simulated with a logistic model assuming an.

  15. Surface alloy formation by adsorption of holmium on Ag/Mo(112) bimetallic surfaces

    Science.gov (United States)

    Kołaczkiewicz, Jan; Oleksy, Czesław

    2018-03-01

    Work function change measurements, low energy electron diffraction (LEED) and density functional theory (DFT) are used to determine the structures formed on Ag/Mo(112) bimetallic surfaces upon deposition of 0.5 monolayer (ML) of holmium. As the bimetallic surfaces, we have chosen the Mo(112) substrate covered with 1 or 2 ML of Ag. Such surfaces have the same symmetry as the Mo(112) face but different electronic properties. LEED experiment indicates that the c(2 × 2) structure is formed on (1 ML Ag)/Mo(112) bimetallic surface upon deposition of 0.5 ML of Ho. DFT calculations show that a type of Ag-Ho surface alloy is formed, with Ho atoms 0.6 Å below the distorted layer of Ag. This is neither a substitutional nor a subsurface alloy. It is found that the adsorption structure formed on the (2 ML Ag)/Mo(112) bimetallic surface depends on the annealing temperature. After deposition of 0.5 ML of Ho at 300 K, the LEED pattern of p(2 × 2) symmetry is observed. Annealing of the overlayer at 640 K irreversibly changes the p(2 × 2) pattern into a pattern of c(2 × 2) type. The results of DFT computations show that the c(2 × 2) structure of the Ag-Ho surface alloy is energetically most favorable. In this structure, 0.5 ML of Ho is between the two monolayers of Ag, and the symmetry of the topmost layer is changed. The work function change calculated for the c(2 × 2) structure is in a good agreement with the measured value (0.22 eV). The results show that adsorption of Ho on the Ag/Mo(112) bimetallic surfaces is substantially different than on the clean Mo(112).

  16. The Arabidopsis Transcription Factor MYB112 Promotes Anthocyanin Formation during Salinity and under High Light Stress.

    Science.gov (United States)

    Lotkowska, Magda E; Tohge, Takayuki; Fernie, Alisdair R; Xue, Gang-Ping; Balazadeh, Salma; Mueller-Roeber, Bernd

    2015-11-01

    MYB transcription factors (TFs) are important regulators of flavonoid biosynthesis in plants. Here, we report MYB112 as a formerly unknown regulator of anthocyanin accumulation in Arabidopsis (Arabidopsis thaliana). Expression profiling after chemically induced overexpression of MYB112 identified 28 up- and 28 down-regulated genes 5 h after inducer treatment, including MYB7 and MYB32, which are both induced. In addition, upon extended induction, MYB112 also positively affects the expression of PRODUCTION OF ANTHOCYANIN PIGMENT1, a key TF of anthocyanin biosynthesis, but acts negatively toward MYB12 and MYB111, which both control flavonol biosynthesis. MYB112 binds to an 8-bp DNA fragment containing the core sequence (A/T/G)(A/C)CC(A/T)(A/G/T)(A/C)(T/C). By electrophoretic mobility shift assay and chromatin immunoprecipitation coupled to quantitative polymerase chain reaction, we show that MYB112 binds in vitro and in vivo to MYB7 and MYB32 promoters, revealing them as direct downstream target genes. We further show that MYB112 expression is up-regulated by salinity and high light stress, environmental parameters that both require the MYB112 TF for anthocyanin accumulation under these stresses. In contrast to several other MYB TFs affecting anthocyanin biosynthesis, MYB112 expression is not controlled by nitrogen limitation or an excess of carbon. Thus, MYB112 constitutes a regulator that promotes anthocyanin accumulation under abiotic stress conditions. © 2015 American Society of Plant Biologists. All Rights Reserved.

  17. PWS/AS MS-MLPA Confirms Maternal Origin of 15q11.2 Microduplication

    Directory of Open Access Journals (Sweden)

    Angelika J. Dawson

    2015-01-01

    Full Text Available The proximal region of the long arm of chromosome 15q11.2-q13 is associated with various neurodevelopmental disorders, including Prader-Willi (PWS and Angelman (AS syndromes, autism, and other developmental abnormalities resulting from deletions and duplications. In addition, this region encompasses imprinted genes that cause PWS or AS, depending on the parent-of-origin. This imprinting allows for diagnosis of PWS or AS based on methylation status using methylation sensitive (MS multiplex ligation dependent probe amplification (MLPA. Maternally derived microduplications at 15q11.2-q13 have been associated with autism and other neuropsychiatric disorders. Multiple methods have been used to determine the parent-of-origin for 15q11.2-q13 microdeletions and microduplications. In the present study, a four-year-old nondysmorphic female patient with developmental delay was found to have a de novo ~5 Mb duplication within 15q11.2 by oligonucleotide genomic array. In order to determine the significance of this microduplication to the clinical phenotype, the parent-of-origin needed to be identified. The PWS/AS MS-MLPA assay is generally used to distinguish between deletion and uniparental disomy (UPD of 15q11.2-q13, resulting in either PWS or AS. However, our study shows that PWS/AS MS-MLPA can also efficiently distinguish the parental origin of duplications of 15q11.2-q13.

  18. Carbon trends. June 2006

    International Nuclear Information System (INIS)

    2006-06-01

    This newsletter makes a monthly synthesis of the European CO 2 market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from June 2005 to May 2006), economic activity indicators (industrial production from March 2005 to March 2006), confidence index of business leaders (from May 2005 to May 2006), changes in energy prices (from June 2005 to May 2006), CO 2 quotas allocated to European Union countries and detailed indicators of CO 2 market, climate, economic activity and energy prices. (J.S.)

  19. Carbon trends. April 2006

    International Nuclear Information System (INIS)

    2006-04-01

    This newsletter makes a monthly synthesis of the European CO 2 market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from April 2005 to March 2006), economic activity indicators (industrial production from January 2005 to January 2006), confidence index of business leaders (from March 2005 to March 2006), changes in energy prices (from April 2005 to March 2006), CO 2 quotas allocated to European Union countries and detailed indicators of CO 2 market, climate, economic activity and energy prices. (J.S.)

  20. Carbon trends. May 2006

    International Nuclear Information System (INIS)

    2006-05-01

    This newsletter makes a monthly synthesis of the European CO 2 market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from May 2005 to April 2006), economic activity indicators (industrial production from February 2005 to February 2006), confidence index of business leaders (from April 2005 to April 2006), changes in energy prices (from May 2005 to April 2006), CO 2 quotas allocated to European Union countries and detailed indicators of CO 2 market, climate, economic activity and energy prices. (J.S.)

  1. 40 CFR 51.112 - Demonstration of adequacy.

    Science.gov (United States)

    2010-07-01

    ... REQUIREMENTS FOR PREPARATION, ADOPTION, AND SUBMITTAL OF IMPLEMENTATION PLANS Control Strategy § 51.112... implements. (1) The adequacy of a control strategy shall be demonstrated by means of applicable air quality... reduction of emissions (or reductions in the growth of emissions) that will result from the implementation...

  2. 37 CFR 11.2 - Director of the Office of Enrollment and Discipline.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Director of the Office of Enrollment and Discipline. 11.2 Section 11.2 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE REPRESENTATION OF OTHERS BEFORE THE UNITED STATES PATENT AND TRADEMARK OFFICE General Provisions General...

  3. 37 CFR 10.112 - Preserving identity of funds and property of client.

    Science.gov (United States)

    2010-07-01

    ... and property of client. 10.112 Section 10.112 Patents, Trademarks, and Copyrights UNITED STATES PATENT... funds and property of client. (a) All funds of clients paid to a practitioner or a practitioner's firm... therein. (2) Funds belonging in part to a client and in part presently or potentially to the practitioner...

  4. Visual processing deficits in 22q11.2 Deletion Syndrome

    Directory of Open Access Journals (Sweden)

    Marjan Biria

    2018-01-01

    The reduced activity of ventral and dorsal visual areas during early stages points to an impairment in visual processing seen both in schizophrenia and 22q11.2DS. During intervals related to perceptual closure, the inverse correlation of high amplitudes with positive symptoms suggests that participants with 22q11.2DS who show an increased brain response to illusory contours during the relevant window for contour processing have less psychotic symptoms and might thus be at a reduced prodromal risk for schizophrenia.

  5. Study of intruder band in 112Sn

    International Nuclear Information System (INIS)

    Ganguly, S.; Banerjee, P.; Ray, I.; Kshetri, R.; Raut, R.; Bhattacharya, S.; Saha-Sarkar, M.; Goswami, A.; Mukhopadhyay, S.; Mukherjee, A.; Mukherjee, G.; Basu, S.K.

    2007-01-01

    Excited states of the positive-parity intruder band in 112 Sn, populated in the 100 Mo( 20 Ne,α4n) reaction at a beam energy of 136 MeV, have been studied. The band has been observed up to 11570.0 keV with spin (24 + ). Mean lifetimes have been measured for six states up to the 22 + , 10335.1 keV level and an upper limit of the lifetime has been estimated for the 11570.0 keV (24 + ) state. The B(E2) values, derived from the present lifetime results, correspond to a moderate quadrupole deformation of β 2 ∼0.18 for states with spin J π >=12 + , and the decrease in B(E2) for the 14 + ->12 + transition is consistent with a ν(h 11/2 ) 2 alignment at ω∼0.35 MeV, predicted by a cranked shell-model calculation. Total Routhian surface calculations predict a triaxial shape following the alignment

  6. CERN Technical Training 2006: Software and System Technologies Curriculum - Scheduled Course Sessions (August-December 2006)

    CERN Multimedia

    2006-01-01

    The Software and System Technologies Curriculum of the CERN Technical Training Programme offers comprehensive training in C++, Java, Perl, Python, XML, OO programming, JCOP/PVSS, database design and Oracle. In the PERL, C++, OO and Java course series there are some places available on the following course sessions, scheduled until the end of this year: PERL 5 - Introduction: 31.8-1.9.2006 (2 days) C++ for Particle Physicists: 16-20.10.2006 (6 half days, the popular course given by Paul Kunz) Object-Oriented Analysis and Design using UML: 17-19.10.2006 (3 days) JAVA 2 Enterprise Edition - Part 1: Web Applications: 19-20.10.2006 (2 days) JAVA - Level 1: 30.10-1.11.2006 (3 days) PERL 5 - Advanced Aspects: 2.11.2006 (1 day) C++ Programming Part 1 - Introduction to Object-Oriented Design and Programming: 14-16.11.2006 (3 days) JAVA - Level 2: 4-7.12.2006 (4 days) C++ Programming Part 2 - Advanced C++ and its Traps and Pitfalls: 12-15.12.2006 (4 days) JAVA 2 Enterprise Edition - Part 2: Enterprise JavaBea...

  7. Education tools for dynamic Bayesian decision-making

    Czech Academy of Sciences Publication Activity Database

    Suzdaleva, Evgenia; Nedoma, Petr

    2006-01-01

    Roč. 5, č. 3 (2006), s. 288-295 ISSN 1790-1979 R&D Projects: GA ČR GP201/06/P434; GA ČR GA102/03/0049 Institutional research plan: CEZ:AV0Z10750506 Keywords : educational system * Bayesian decision-making * probabilistic mixtures Subject RIV: JC - Computer Hardware ; Software http://library.utia.cas.cz/prace/20060144.pdf

  8. Chymase-dependent generation of angiotensin II from angiotensin-(1-12 in human atrial tissue.

    Directory of Open Access Journals (Sweden)

    Sarfaraz Ahmad

    Full Text Available Since angiotensin-(1-12 [Ang-(1-12] is a non-renin dependent alternate precursor for the generation of cardiac Ang peptides in rat tissue, we investigated the metabolism of Ang-(1-12 by plasma membranes (PM isolated from human atrial appendage tissue from nine patients undergoing cardiac surgery for primary control of atrial fibrillation (MAZE surgical procedure. PM was incubated with highly purified ¹²⁵I-Ang-(1-12 at 37°C for 1 h with or without renin-angiotensin system (RAS inhibitors [lisinopril for angiotensin converting enzyme (ACE, SCH39370 for neprilysin (NEP, MLN-4760 for ACE2 and chymostatin for chymase; 50 µM each]. ¹²⁵I-Ang peptide fractions were identified by HPLC coupled to an inline γ-detector. In the absence of all RAS inhibitor, ¹²⁵I-Ang-(1-12 was converted into Ang I (2±2%, Ang II (69±21%, Ang-(1-7 (5±2%, and Ang-(1-4 (2±1%. In the absence of all RAS inhibitor, only 22±10% of ¹²⁵I-Ang-(1-12 was unmetabolized, whereas, in the presence of the all RAS inhibitors, 98±7% of ¹²⁵I-Ang-(1-12 remained intact. The relative contribution of selective inhibition of ACE and chymase enzyme showed that ¹²⁵I-Ang-(1-12 was primarily converted into Ang II (65±18% by chymase while its hydrolysis into Ang II by ACE was significantly lower or undetectable. The activity of individual enzyme was calculated based on the amount of Ang II formation. These results showed very high chymase-mediated Ang II formation (28±3.1 fmol × min⁻¹ × mg⁻¹, n = 9 from ¹²⁵I-Ang-(1-12 and very low or undetectable Ang II formation by ACE (1.1±0.2 fmol×min⁻¹ × mg⁻¹. Paralleling these findings, these tissues showed significant content of chymase protein that by immunocytochemistry were primarily localized in atrial cardiac myocytes. In conclusion, we demonstrate for the first time in human cardiac tissue a dominant role of cardiac chymase in the formation of Ang II from Ang-(1-12.

  9. Carbon trends. July 2006

    International Nuclear Information System (INIS)

    2006-07-01

    This newsletter makes a monthly synthesis of the European CO 2 market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from June 2005 to June 2006), economic activity indicators (industrial production index from April 2005 to April 2006), confidence index of business leaders (from June 2005 to June 2006), changes in energy prices (from July 2005 to June 2006), CO 2 quotas allocated to European Union countries and detailed indicators of CO 2 market, climate, economic activity and energy prices. (J.S.)

  10. Multitasking Abilities in Adolescents With 22q11.2 Deletion Syndrome: Results From an Experimental Ecological Paradigm.

    Science.gov (United States)

    Schneider, Maude; Eliez, Stephan; Birr, Julie; Menghetti, Sarah; Debbané, Martin; Van der Linden, Martial

    2016-03-01

    The 22q11.2 deletion syndrome (22q11.2DS) is associated with cognitive and functional impairments and increased risk for schizophrenia. We characterized multitasking abilities of adolescents with 22q11.2DS using an experimental naturalistic setting and examined whether multitasking impairments were associated with real-world functioning and negative symptoms. Thirty-nine adolescents (19 with 22q11.2DS and 20 controls) underwent the Multitasking Evaluation for Adolescents. Real-world functioning and clinical symptoms were assessed in participants with 22q11.2DS. Adolescents with 22q11.2DS performed poorly in the multitasking evaluation. Our data also suggest that multitasking abilities are related to adaptive functioning in the practical domain and negative symptoms. This study shows that adolescents with 22q11.2DS are characterized by multitasking impairments, which may be relevant for several aspects of the clinical phenotype.

  11. Supplemental design requirements document enhanced radioactive and mixed waste storage Phase V Project W-112

    International Nuclear Information System (INIS)

    Ocampo, V.P.; Boothe, G.F.; Greager, T.M.; Johnson, K.D.; Kooiker, S.L.; Martin, J.D.

    1994-11-01

    This document provides additional and supplemental information to WHC-SD-W112-FDC-001, Project W-112 for radioactive and mixed waste storage. It provides additional requirements for the design and summarizes Westinghouse Hanford Company key design guidance and establishes the technical baseline agreements to be used for definitive design of the Project W-112 facilities

  12. 48 CFR 49.112-2 - Final payment.

    Science.gov (United States)

    2010-10-01

    ... voucher or invoice and forward the documents to the disbursing officer for payment. (b) Settlement by...) Construction contracts. In the case of construction contracts, before forwarding the final payment voucher, the... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Final payment. 49.112-2...

  13. 38 CFR 75.112 - Definitions and terms.

    Science.gov (United States)

    2010-07-01

    ... personal privacy and proprietary information. Data breach means the loss or theft of, or other unauthorized...) INFORMATION SECURITY MATTERS Data Breaches § 75.112 Definitions and terms. For purposes of this subpart... the confidentiality or integrity of the data. Data breach analysis means the process used to determine...

  14. An interictal schizophrenia-like psychosis in an adult patient with 22q11.2 deletion syndrome

    OpenAIRE

    Yasutaka Tastuzawa; Kanako Sekinaka; Tetsufumi Suda; Hiroshi Matsumoto; Hiroyuki Otabe; Shigeaki Nonoyama; Aihide Yoshino

    2015-01-01

    In addition to causing polymalformative syndrome, 22q11.2 deletion can lead to various neuropsychiatric disorders including mental retardation, psychosis, and epilepsy. However, few reports regarding epilepsy-related psychosis in 22q11.2 deletion syndrome (22q11.2DS) exist. We describe the clinical characteristics and course of 22q11.2DS in a Japanese patient with comorbid mild mental retardation, childhood-onset localization-related epilepsy, and adult-onset, interictal schizophrenia-like ps...

  15. Movement Disorders and Other Motor Abnormalities in Adults With 22q11.2 Deletion Syndrome

    Science.gov (United States)

    Boot, Erik; Butcher, Nancy J; van Amelsvoort, Thérèse AMJ; Lang, Anthony E; Marras, Connie; Pondal, Margarita; Andrade, Danielle M; Fung, Wai Lun Alan; Bassett, Anne S

    2015-01-01

    Movement abnormalities are frequently reported in children with 22q11.2 deletion syndrome (22q11.2DS), but knowledge in this area is scarce in the increasing adult population. We report on five individuals illustrative of movement disorders and other motor abnormalities in adults with 22q11.2DS. In addition to an increased susceptibility to neuropsychiatric disorders, seizures, and early-onset Parkinson disease, the underlying brain dysfunction associated with 22q11.2DS may give rise to an increased vulnerability to multiple movement abnormalities, including those influenced by medications. Movement abnormalities may also be secondary to treatable endocrine diseases and congenital musculoskeletal abnormalities. We propose that movement abnormalities may be common in adults with 22q11.2DS and discuss the implications and challenges important to clinical practice. PMID:25684639

  16. Guide 52 status update : electronic capture of well test data

    International Nuclear Information System (INIS)

    Kronemeyer, W.

    1998-01-01

    As of 1 January 1999 the electronic submission of well test data is a stated requirement of the Alberta Energy and Utilities Board (EUB). Well test data is used for reserves assessment, reservoir characterization, depletion mechanism, enhanced productivity, pooling, equity disputes, monitoring pool depletion, and monitoring enhanced recovery. The challenge will be the inter-operability with popular e-mail software and security threats. The system, which will be available to everyone, promises to be affordable, simple, secure, flexible, able to convert charts and graphs, use recognized acceptable standards, and be compatible with EUB databases

  17. Clearing the air: Alberta a model of success in decreasing venting, flaring

    International Nuclear Information System (INIS)

    Harrison, L.

    2004-01-01

    An historical review of flaring and venting in the Alberta oilfields is presented. The story begins with gas production in the Turner Valley, Alberta in 1931, Western Canada's first, largest and most productive source of oil and naphtha until the discovery of Leduc in 1947. Gas production at Turner Valley reached 500 mmcf per day, of which about 486 mmcf was flared. Through the efforts of the Alberta Energy and Utilities Board (EUB) and its predecessors venting and flaring was drastically cut, to the point where in 2003 the World Bank Group, an agency of the United Nations, approached the EUB to present the Alberta flaring and venting reduction model to developing countries. Accordingly, a Flaring Workshop was held at Calgary in October 2003, attended by delegates from Algeria, Angola, Cameroon, Indonesia and Nigeria. The article also details the EUB's requirements for upstream flaring in Alberta, as laid down in 'Guide 60'. The draft Guide was released in January 2003, the final draft is targeted for February 2004. In brief, the Guide requires operators, by means of a 'decision tree analysis' method which is described in the Guide, to evaluate whether it is possible to reduce or eliminate flaring and venting; it also requires operators to evaluate economic feasibility, and to determine the feasibility of conserving as much gas as possible. New developments in the field of sensors, controls and optical flow meters are also reviewed. An appended statistical summary of gas flaring trends in selected countries, compiled by the World Bank in 2000 shows Nigeria, Iran, Russia, Algeria and Mexico as the countries with the highest volumes of flaring. To give an indication of the volume of gas wasted through flaring, it is reliably estimated that the amount of gas flared in 2000 by African countries alone, could have fuelled power plants to generate sufficient electric power to meet fully half of the continent's needs for electric power. 1 tab., 2 figs

  18. 40 CFR 266.112 - Regulation of residues.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Hazardous Waste Burned in Boilers and Industrial Furnaces § 266.112 Regulation of... furnace is not excluded from the definition of a hazardous waste under § 261.4(b) (4), (7), or (8) unless...

  19. National Wood-fuel Programme 2000-2006. Activity Report 2000-2006

    International Nuclear Information System (INIS)

    2008-01-01

    When ADEME launched its Wood-fuel programme throughout all of France in late 1999, its aim was to guide this resource supply chain to maturity and stable development in all user sectors: domestic, multi-family housing, commercial/institutional and industrial applications. To this end the Wood-fuel Programme 2000-2006 was assigned objectives and endowed with significant financial means for studies and coordination in order to support and carry out general-interest projects, piloted by ADEME. The stated goal was to replace fossil fuels, avoid carbon emissions and establish quality assurance standards for household firewood and wood-fired devices. This report presents: 1 - the Wood Energy stakes for the environment, for employment, and for the economy, the biomass energy net benefits; 2 - the Wood Energy key figures: Production and consumption, Single-family homes and wood heating, Breakdown of types of devices used, Sales of wood-fired devices, Number of housing/institutional boilers in use, Number of industrial boilers in use; 3 - the Wood Energy objectives: Domestic heating, Industrial boiler plants, District heating for housing/institutional/commercial uses; 4 - the Wood Energy program operation: Program coordination by ADEME, Partnerships and State-Region planning agreements, 2000-2006 funding system (modified in 2004) and Other financial instruments; 5 - the 2000-2006 assessment: Main results, Conclusions and recommendations, Evaluation contributions: five key points, Evaluation of employment in the solid biofuels supply chain, Supply for community, institutional and commercial boilers; 6 - Information and communication: Initiatives supported or accompanied by ADEME between 2000 and 2004, Publications supported by ADEME. In appendix: fuels and energy content, regional assessments, national research program on bio-energies - PNRB 2006 (Review and stakes, PNRB results in 2006), wood heating R and D, studies funded by ADEME, 2006 ADEME's correspondents, glossary

  20. Changes in psychosocial work factors in the French working population between 2006 and 2010.

    Science.gov (United States)

    Malard, Lucile; Chastang, Jean-François; Niedhammer, Isabelle

    2015-02-01

    The aim of the study was to assess the changes in psychosocial work factors in the French working population between 2006 and 2010 and to examine potential differential changes according to age, occupation, public/private sector, work contract and self-employed/employee status. The study sample included 5,600 workers followed up from 2006 to 2010 from the national representative Santé et Itinéraire Professionnel (SIP) survey. Psychosocial work factors included decision latitude, psychological demands, social support, reward, overcommitment, long working hours, predictability, night- and shift work, emotional demands, role conflict, ethical conflict, tensions with the public, job insecurity and work-life imbalance, and were measured using scores. Linear regressions were used to analyse the change in the scores of these factors adjusted for age and initial score. All analyses were stratified by gender. Psychosocial work factors worsened between 2006 and 2010: decision latitude, social support, reward, role conflict and work-life imbalance for both genders, and psychological demands, emotional demands, ethical conflict and tensions with the public for women. Differential changes according to age, occupation, public/private sector, work contract and self-employed/employee status were observed suggesting that some groups may be more likely to be exposed to negative changes especially the younger, low- and high-skilled and public sector workers. Monitoring exposure to psychosocial work factors over time may be crucial, and prevention policies should take into account that deterioration of psychosocial work factors may be sharper among subgroups such as younger, low- and high-skilled and public sector workers.

  1. 22q11.2 deletion syndrome lowers seizure threshold in adult patients without epilepsy.

    Science.gov (United States)

    Wither, Robert G; Borlot, Felippe; MacDonald, Alex; Butcher, Nancy J; Chow, Eva W C; Bassett, Anne S; Andrade, Danielle M

    2017-06-01

    Previous studies examining seizures in patients with 22q11.2 deletion syndrome (22q11.2DS) have focused primarily on children and adolescents. In this study we investigated the prevalence and characteristics of seizures and epilepsy in an adult 22q11.2DS population. The medical records of 202 adult patients with 22q11.2DS were retrospectively reviewed for documentation of seizures, electroencephalography (EEG) reports, and magnetic resonance imaging (MRI) findings. Epilepsy status was assigned in accordance with 2010 International League Against Epilepsy Classification. Of 202 patients, 32 (15.8%) had a documented history of seizure. Of these 32, 23 (71.8%) had acute symptomatic seizures, usually associated with hypocalcemia and/or antipsychotic or antidepressant use. Nine patients (9/32, 28%; 9/202, 4%) met diagnostic criteria for epilepsy. Two patients had genetic generalized epilepsy; two patients had focal seizures of unknown etiology; two had epilepsy due to malformations of cortical development; in two the epilepsy was due to acquired structural changes; and in one patient the epilepsy could not be further classified. Similarly to children, the prevalence of epilepsy and acute symptomatic seizures in adults with 22q11.2DS is higher than in the general population. Hypocalcemia continues to be a risk factor for adults, but differently from kids, the main cause of seizures in adults with 22q11.2DS is exposure to antipsychotics and antidepressants. Further prospective studies are warranted to investigate how 22q11.2 microdeletion leads to an overall decreased seizure threshold. Wiley Periodicals, Inc. © 2017 International League Against Epilepsy.

  2. File list: His.PSC.05.H2BS112GlcNAc.AllCell [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.PSC.05.H2BS112GlcNAc.AllCell hg19 Histone H2BS112GlcNAc Pluripotent stem cell h...ttp://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.PSC.05.H2BS112GlcNAc.AllCell.bed ...

  3. 77 FR 26321 - Reed College, Reed Research Nuclear Reactor, Renewed Facility Operating License No. R-112

    Science.gov (United States)

    2012-05-03

    ... Nuclear Reactor, Renewed Facility Operating License No. R-112 AGENCY: Nuclear Regulatory Commission... Commission (NRC or the Commission) has issued renewed Facility Operating License No. R- 112, held by Reed... License No. R-112 will expire 20 years from its date of issuance. The renewed facility operating license...

  4. CERN Technical Training 2006: Software and System Technologies Curriculum - Scheduled Course Sessions (October-December 2006)

    CERN Multimedia

    2006-01-01

    he Software and System Technologies Curriculum of the CERN Technical Training Programme offers comprehensive training in C++, Java, Perl, Python, XML, OO programming, JCOP/PVSS, database design and Oracle. In the PERL, C++, OO and Java course series there are some places available on the following course sessions, scheduled until the end of this year: Object-Oriented Analysis and Design using UML: 17-19 October 2006 (3 days) JAVA 2 Enterprise Edition - Part 1: Web Applications: 19-20 October 2006 (2 days) JAVA - Level 1: 30 Oct. -1 Nov. 2006 (3 days) PERL 5 - Advanced Aspects: 2 November 2006 (1 day) C++ Programming Part 1 - Introduction to Object-Oriented Design and Programming: 14-16 November 2006 (3 days) JAVA - Level 2: 4-7 December 2006 (4 days) C++ Programming Part 2 - Advanced C++ and its Traps and Pitfalls: 12-15 December 2006 (4 days) JAVA 2 Enterprise Edition - Part 2: Enterprise JavaBeans : 18.20 December 2006 (3 days) All the above sessions will be given in English, at the CERN Training Centre....

  5. Subthreshold social cognitive deficits may be a key to distinguish 22q11.2DS from schizophrenia.

    Science.gov (United States)

    Peyroux, Elodie; Rigard, Caroline; Saucourt, Guillaume; Poisson, Alice; Plasse, Julien; Franck, Nicolas; Demily, Caroline

    2018-03-25

    Social cognitive impairments are core features in 22q11.2 deletion syndrome (22q11.2DS) and schizophrenia (SCZ). Indeed, adults with 22q.11.2 DS often have poorer social competence as well as poorer performance on measures of social cognitive skills (emotion recognition and theory of mind, ToM) compared with typically developing people. However, studies comparing specific social cognitive components in 22q11.2DS and SCZ have not yet been widely conducted. In this study we compared performances of 22q11.2DS and SCZ on both facial emotion recognition and ToM. Patients with 22q11.2DS (n = 18) and matched SCZ patients were recruited. After neuropsychological testing, the facial emotion recognition test assessed the patients' ability to recognize six basic, universal emotions (joy, anger, sadness, fear, disgust, and contempt). The Versailles-situational intentional reading evaluated ToM with six scenes from movies showing characters in complex interactions (involving hints, lies, and indirect speech). We show that 22q11.2DS exhibited significantly lower performance in emotion recognition than SCZ patients did, especially for disgust, contempt, and fear. This impairment seems to be a core cognitive phenotype in 22q11.2DS, regardless of the presence of SCZ symptoms. Concerning ToM, our results may highlight the same impairment level in 22q11.2DS and SCZ but require to be replicated in a larger cohort. Our results document the existence of threshold social cognitive deficits distinguishing 22q11.2DS from SCZ. © 2018 John Wiley & Sons Australia, Ltd.

  6. Speech and language abilities of children with the familial form of 22q11.2 deletion syndrome

    Directory of Open Access Journals (Sweden)

    Rakonjac Marijana

    2016-01-01

    Full Text Available The 22q11.2 Deletion Syndrome (22q11.2DS, which encompasses Shprintzen syndrome, DiGeorge and velocardiofacial syndrome, is the most common microdeletion syndrome in humans with an estimated incidence of approximately 1/4000 per live births. After Down syndrome, it is the second most common genetic syndrome associated with congenital heart malformations. The mode of inheritance of the 22q11.2DS is autosomal dominant. In approximately 72 - 94% of the cases the deletion has occurred de novo, while in 6 to 28% of patients deletion was inherited from a parent. As a part of a multidisciplinary study we examined the speech and language abilities of members of two families with inherited form of 22q11.2DS. The presence of 22q11.2 microdeletion was revealed by fluorescence in situ hybridization (FISH and/or multiplex ligation-dependent probe amplification (MLPA. In one family we detected 1.5 Mb 22q11.2 microdeletion, while in the other family we found 3Mb microdeletion. Patients from both families showed delays in cognitive, socio-emotional, speech and language development. Furthermore, we found considerable variability in the phenotypic characteristics of 22q11.2DS and the degree of speech-language pathology not only between different families with 22q11.2 deletion, but also among members of the same family. In addition, we detected no correlation between the phenotype and the size of 22q11.2 microdeletion.

  7. Student decisions about lecture attendance: do electronic course materials matter?

    Science.gov (United States)

    Billings-Gagliardi, Susan; Mazor, Kathleen M

    2007-10-01

    This study explored whether first-year medical students make deliberate decisions about attending nonrequired lectures. If so, it sought to identify factors that influence these decisions, specifically addressing the potential impact of electronic materials. Medical students who completed first-year studies between 2004 and 2006 responded to an open-ended survey question about their own lecture-attendance decisions. Responses were coded to capture major themes. Students' ratings of the electronic materials were also examined. Most respondents made deliberate attendance decisions. Decisions were influenced by previous experiences with the lecturer, predictions of what would occur during the session itself, personal learning preferences, and learning needs at that particular time, with the overriding goal of maximizing learning. Access to electronic materials did not influence students' choices. Fears that the increasing availability of technology-enhanced educational materials has a negative impact on lecture attendance seem unfounded.

  8. Characterization of the apoptotic response induced by the cyanine dye D112: a potentially selective anti-cancer compound.

    Directory of Open Access Journals (Sweden)

    Ning Yang

    Full Text Available Chemotherapeutic drugs that are used in anti-cancer treatments often cause the death of both cancerous and noncancerous cells. This non-selective toxicity is the root cause of untoward side effects that limits the effectiveness of therapy. In order to improve chemotherapeutic options for cancer patients, there is a need to identify novel compounds with higher discrimination for cancer cells. In the past, methine dyes that increase the sensitivity of photographic emulsions have been investigated for anti-cancer properties. In the 1970's, Kodak Laboratories initiated a screen of approximately 7000 dye structural variants for selective toxicity. Among these, D112 was identified as a promising compound with elevated toxicity against a colon cancer cell line in comparison to a non-transformed cell line. Despite these results changing industry priorities led to a halt in further studies on D112. We decided to revive investigations on D112 and have further characterized D112-induced cellular toxicity. We identified that in response to D112 treatment, the T-cell leukemia cell line Jurkat showed caspase activation, mitochondrial depolarization, and phosphatidylserine externalization, all of which are hallmarks of apoptosis. Chemical inhibition of caspase enzymatic activity and blockade of the mitochondrial pathway through Bcl-2 expression inhibited D112-induced apoptosis. At lower concentrations, D112 induced growth arrest. To gain insight into the molecular mechanism of D112 induced mitochondrial dysfunction, we analyzed the intracellular localization of D112, and found that D112 associated with mitochondria. Interestingly, in the cell lines that we tested, D112 showed increased toxicity toward transformed versus non-transformed cells. Results from this work identify D112 as a potentially interesting molecule warranting further investigation.

  9. The Development of Cognitive Control in Children with Chromosome 22q11.2 Deletion Syndrome

    Directory of Open Access Journals (Sweden)

    Heather M Shapiro

    2014-06-01

    Full Text Available Chromosome 22q11.2 Deletion Syndrome (22q11.2DS is caused by the most common human microdeletion, and it is associated with cognitive impairments across many domains. While impairments in cognitive control have been described in children with 22q11.2DS, the nature and development of these impairments are not clear. Children with 22q11.2DS and typically developing children (TD were tested on four well-validated tasks aimed at measuring specific foundational components of cognitive control: response inhibition, cognitive flexibility, and working memory. Molecular assays were also conducted in order to examine genotype of catechol-O-methyltransferase (COMT, a gene located within the deleted region in 22q11.2DS and hypothesized to play a role in cognitive control. Mixed model regression analyses were used to examine group differences, as well as age-related effects on cognitive control component processes in a cross-sectional analysis. Regression models with COMT genotype were also conducted in order to examine potential effects of the different variants of the gene. Response inhibition, cognitive flexibility, and working memory were impaired in children with 22q11.2DS relative to TD children, even after accounting for global intellectual functioning (as measured by full-scale IQ. When compared with TD individuals, children with 22q11.2DS demonstrated atypical age-related patterns of response inhibition and cognitive flexibility. Both groups demonstrated typical age-related associations with working memory. The results of this cross-sectional analysis suggest a specific aberration in the development of systems mediating response inhibition in a sub-set of children with 22q11.2DS. It will be important to follow up with longitudinal analyses to directly examine these developmental trajectories, and correlate neurocognitive variables with clinical and adaptive outcome measures.

  10. An interictal schizophrenia-like psychosis in an adult patient with 22q11.2 deletion syndrome

    Directory of Open Access Journals (Sweden)

    Yasutaka Tastuzawa

    2015-01-01

    Full Text Available In addition to causing polymalformative syndrome, 22q11.2 deletion can lead to various neuropsychiatric disorders including mental retardation, psychosis, and epilepsy. However, few reports regarding epilepsy-related psychosis in 22q11.2 deletion syndrome (22q11.2DS exist. We describe the clinical characteristics and course of 22q11.2DS in a Japanese patient with comorbid mild mental retardation, childhood-onset localization-related epilepsy, and adult-onset, interictal schizophrenia-like psychosis. From a diagnostic viewpoint, early detection of impaired intellectual functioning and hyperprolinemia in patients with epilepsy with 22q11.2DS may be helpful in predicting the developmental timing of interictal psychosis. From a therapeutic viewpoint, special attention needs to be paid to phenytoin-induced hypocalcemia in this syndrome.

  11. Dislocation structures of Σ3 {112} twin boundaries in face centered cubic metals

    Science.gov (United States)

    Wang, J.; Anderoglu, O.; Hirth, J. P.; Misra, A.; Zhang, X.

    2009-07-01

    High resolution transmission electron microscopy of nanotwinned Cu films revealed Σ3 {112} incoherent twin boundaries (ITBs), with a repeatable pattern involving units of three {111} atomic planes. Topological analysis shows that Σ3 {112} ITBs adopt two types of atomic structure with differing arrangements of Shockley partial dislocations. Atomistic simulations were performed for Cu and Al. These studies revealed the structure of the two types of ITBs, the formation mechanism and stability of the associated 9R phase, and the influence of stacking fault energies on them. The results suggest that Σ3 {112} ITBs may migrate through the collective glide of partial dislocations.

  12. 1997/98 Orphan Well Fund annual report

    International Nuclear Information System (INIS)

    1999-04-01

    Alberta's Orphan Well Fund (previously referred as the Abandonment Fund) is funded by the oil and gas industry with provincial government support and approval. It was created to enforce and improve regulations regarding orphan wells. 1997/98 marked the year in which Orphan Well Fund activities included pipeline abandonments, facility decommissioning, and well site reclamation. The first part of this report includes the annual report of the Orphan Fund, while the second part includes the report on the Energy and Utilities Board's (EUB's) Liability Management activities which are an important part of enforcing and improving provincial regulations in the prevention of orphan wells. The fund allows liability management to be done with industry's dollars rather than taxpayer's dollars. Highlights for the year include the successful completion on eleven downhole and surface wells. Expanded activities also included the abandonment of eleven pipelines, and facilities decommissioning work at five locations. The report also includes a financial review, and a summary of the future goals of the program. The EUB enforcement activities and operations, as well as the EUB orphan prevention activities are also reviewed. tabs

  13. MicroRNA Dysregulation, Gene Networks, and Risk for Schizophrenia in 22q11.2 Deletion Syndrome

    Science.gov (United States)

    Merico, Daniele; Costain, Gregory; Butcher, Nancy J.; Warnica, William; Ogura, Lucas; Alfred, Simon E.; Brzustowicz, Linda M.; Bassett, Anne S.

    2014-01-01

    The role of microRNAs (miRNAs) in the etiology of schizophrenia is increasingly recognized. Microdeletions at chromosome 22q11.2 are recurrent structural variants that impart a high risk for schizophrenia and are found in up to 1% of all patients with schizophrenia. The 22q11.2 deletion region overlaps gene DGCR8, encoding a subunit of the miRNA microprocessor complex. We identified miRNAs overlapped by the 22q11.2 microdeletion and for the first time investigated their predicted target genes, and those implicated by DGCR8, to identify targets that may be involved in the risk for schizophrenia. The 22q11.2 region encompasses seven validated or putative miRNA genes. Employing two standard prediction tools, we generated sets of predicted target genes. Functional enrichment profiles of the 22q11.2 region miRNA target genes suggested a role in neuronal processes and broader developmental pathways. We then constructed a protein interaction network of schizophrenia candidate genes and interaction partners relevant to brain function, independent of the 22q11.2 region miRNA mechanisms. We found that the predicted gene targets of the 22q11.2 deletion miRNAs, and targets of the genome-wide miRNAs predicted to be dysregulated by DGCR8 hemizygosity, were significantly represented in this schizophrenia network. The findings provide new insights into the pathway from 22q11.2 deletion to expression of schizophrenia, and suggest that hemizygosity of the 22q11.2 region may have downstream effects implicating genes elsewhere in the genome that are relevant to the general schizophrenia population. These data also provide further support for the notion that robust genetic findings in schizophrenia may converge on a reasonable number of final pathways. PMID:25484875

  14. Orphan drugs expenditure in the Netherlands in the period 2006–2012

    OpenAIRE

    Kanters, Tim A; Steenhoek, Adri; Hakkaart, Leona

    2014-01-01

    textabstractBackground: The relatively low budget impact of orphan drugs is often used as an argument in reimbursement decisions. However, overall, the budget impact of orphan drugs can still be substantial. In this study, we assess the uptake and budget impact of orphan drugs in the Netherlands.Methods. We examined the number of orphan drugs, the number of patients and budget impact of orphan drugs in the Netherlands in the period 2006 to 2012, both for inpatient and outpatient orphan drugs....

  15. Graves disease and IgA deficiency as manifestations of 22q11.2 deletion syndrome:

    OpenAIRE

    Silva, João Miguel de Almeida; Silva, Cecília Pereira; Melo, Flavio Fernando Nogueira de; Silva, Luis Alberto A.; Utagawa, Claudia Yamada

    2010-01-01

    A síndrome de deleção 22q11.2 (SD22q11.2) está associada à alta variabilidade fenotípica, abrangendo o espectro velocardiofacial/síndrome de DiGeorge. Manifestações autoimunes, endocrinológicas e de imunodeficiência vêm sendo relatadas associadas à síndrome. O objetivo deste estudo foi relatar um caso de SD22q11.2 associado à deficiência de IgA e à doença de Graves e rever a literatura visando verificar a frequência dessas alterações na SD22q11.2. Os distúrbios autoimunes, cada vez mais relac...

  16. 16p11.2 Deletion Mice Display Cognitive Deficits in Touchscreen Learning and Novelty Recognition Tasks

    Science.gov (United States)

    Yang, Mu; Lewis, Freeman C.; Sarvi, Michael S.; Foley, Gillian M.; Crawley, Jacqueline N.

    2015-01-01

    Chromosomal 16p11.2 deletion syndrome frequently presents with intellectual disabilities, speech delays, and autism. Here we investigated the Dolmetsch line of 16p11.2 heterozygous (+/-) mice on a range of cognitive tasks with different neuroanatomical substrates. Robust novel object recognition deficits were replicated in two cohorts of 16p11.2

  17. 78 FR 22761 - Delegation of Functions Under Sections 404 and 406 of Public Law 112-208

    Science.gov (United States)

    2013-04-16

    ...--Delegation of Functions Under Sections 404 and 406 of Public Law 112-208 Presidential Determination No. 2013... and 406 of Public Law 112-208 Memorandum for the Secretary of State [and] the Secretary of the... conferred upon the President by sections 404 and 406 of Public Law 112-208 as follows: I hereby delegate to...

  18. High-spin states in odd-odd 106,108,110,112Rh

    International Nuclear Information System (INIS)

    Fotiades, N.; Cizewski, J.A.; Kruecken, R.; McNabb, D.P.; Becker, J.A.; Bernstein, L.A.; Younes, W.; Clark, R.M.; Fallon, P.; Lee, I.Y.; Macchiavelli, A.O.

    2003-01-01

    The level structures of 106,108,110,112 Rh have been studied in the fission of the compound system formed in three different heavy-ion induced reactions. Sequences of five transitions, together with weak crossover transitions, have been assigned to each isotope based on coincidences with known transitions in the complementary fragments. Comparison with the lighter odd-odd Rh isotopes supports assignment of these sequences as the yrast bands built on the πg 9/2 xνh 11/2 configuration

  19. Tank 241-BY-112 vapor sampling and analysis tank characterization report

    International Nuclear Information System (INIS)

    Huckaby, J.L.

    1995-01-01

    Tank 241-BY-112 headspace gas and vapor samples were collected and analyzed to help determine the potential risks to tank farm workers due to fugitive emissions from the tank. The drivers and objectives of waste tank headspace sampling and analysis are discussed in open-quotes Program Plan for the Resolution of Tank Vapor Issues.close quotes Tank 241-BY-112 was vapor sampled in accordance with open-quotes Data Quality Objectives for Generic In-Tank Health and Safety Issue Resolution.close quotes

  20. Summary of issues and decisions: Workshopon the politics of digital ...

    African Journals Online (AJOL)

    Summary of issues and decisions: Workshopon the politics of digital initiatives concerning africa, 4-5 August 2006, University of Illinois at Urbana-champaign. DK Easterbrook. Abstract. No Abstract. Innovation Vol.34 () 2007: pp. 1-3. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD ...

  1. Swiss electricity statistics 2006

    International Nuclear Information System (INIS)

    2007-01-01

    This comprehensive report made by the Swiss Federal Office of Energy (SFOE) presents the statistics on electricity production and usage in Switzerland for the year 2006. First of all, an overview of Switzerland's electricity supply in 2006 is presented. Details are noted of the amounts generated by different sources including nuclear, hydro-power, storage schemes and thermal power stations as well as energy transfer with neighbouring countries. A second chapter takes a look at the balance of imports and exports with illustrative flow diagrams along with tables for total figures from 1950 through to 2006. For the summer and winter periods, figures from 1995 to 2006 are presented. The third chapter examines the production of electricity in the various types of power stations and the developments over the years 1950 to 2006, whereby, for example, statistics on regional generation and power station type are looked at. The fourth chapter looks at electricity consumption in various sectors from 1983 to 2006 and compares the figures with international data. The fifth chapter looks at generation, consumption and loading on particular, selected days and chapter six considers energy exchange with Switzerland's neighbours. Chapter seven takes a look at possibilities for extending generation facilities in the period up to 2013

  2. Maailma turism 2006 / Piret Kallas

    Index Scriptorium Estoniae

    Kallas, Piret

    2007-01-01

    2006. aastal tehti kogu maailmas 842 miljonit ööbimisega välisreisi, mis on 4,5 protsenti enam kui 2005. aastal. Maailma turismitrendid 2006-2007, prognoos 2007. aastaks. Euroopa turismi arengust 2006. aastal. Allikas: UNWTO World Tourism Barometer, jaan. 2007

  3. Youth Homelessness 2006

    Science.gov (United States)

    MacKenzie, David; Chamberlain, Chris

    2008-01-01

    The third national census of homeless school students, conducted in 2006, found that the number of homeless students had decreased since 2001. There were 9,389 homeless students in 2006 compared with 12,227 in 2001. Three groups were over-represented in the homeless population: Indigenous students, young people from single parent and blended…

  4. Caregiving decision making by older mothers and adult children: process and expected outcome.

    Science.gov (United States)

    Cicirelli, Victor G

    2006-06-01

    Dyadic caregiving decision making was studied in 30 mother-son and 29 mother-daughter pairs (mother's age=65-94 years) who responded to a vignette depicting a caregiving decision situation. The observed decision-making process of mother-child pairs was largely naturalistic, with few alternatives proposed and quick convergence to a decision followed by a postdecision justification; a degree of more rational decision making was seen in some pairs. Among significant findings, adult children, especially sons, dominated the decision process, doing more talking and introducing more alternatives than did their mothers, who played a more subordinate role. Mother-son pairs expected more negative outcomes and greater regrets regarding their decisions than mother-daughter pairs. Closeness of the parent-child relationship influenced the decision-making process, expected outcomes, and regrets. Copyright (c) 2006 APA, all rights reserved.

  5. FAKTOR-FAKTOR PENENTU PENGAMBILAN KEPUTUSAN PEMILIHAN MAYOR MAHASISWA S1 TAHUN AKADEMIK 2005/2006

    Directory of Open Access Journals (Sweden)

    Megawati Simanjuntak

    2008-01-01

    Full Text Available In determining major choosing, students as consumers were influenced by internal and external factors. The aimed of this research was to study the determinant factors in decision making of undergraduate students academicyear 2005/2006. The research was conducted in Bogor Agricultural University (IPB Dramaga, Bogor since May to November 2006 by using one time cross sectional study. Sampling technique used was stratified random sampling with 331 samples. Data were collected by using questionnaire as a guide. Most of samples had determined their major since they entered IPB. Alumni job prospect was the first information they looked when read major’s information. For most samples, open house and promotion activities in Graduate Square influenced their major decision making. In addition, self interest (66.6% and alumni job prospect (53.2% influenced major decision making. This time, most samples (61.9% had first major choosing and according to them the major suited their desire (74.0%. Logistic regression showed that samples with cumulative grade index > 2.75 had opportunity 3.5 times to obtain major suited to their desire compare with samples with cumulative grade index < 2.75. Major determine based on self interest had opportunity 1.467 times to obtain major suit to their desire compare with samples not based on self interest. The active seeking information samples had opportunity 1.489 times to obtain major suited their desire compare with passive seeking information samples.

  6. The regulatory environment for drilling and oilfield waste disposal and remediation in Alberta

    International Nuclear Information System (INIS)

    MacLachlan, L.J.; Stimpson, S.

    1999-01-01

    The legislative basis of regulation of all aspects of oilfield waste, including all oil and gas, oil sands, and oilfield waste management facility operations in Alberta is discussed. The appropriate waste management practices for the upstream petroleum industry and all waste stream associated with the petroleum industry are outlined. Major topics discussed include: (1) the roles and the jurisdictions of the Alberta Energy and Utilities Board (EUB) and Alberta Environmental Protection (AEP), (2) drilling waste and oilfield waste disposal, EUB guides 50 and 58, (3) wellsite abandonment and reclamation of wellsites, (4) spills and contaminated sites, (5) environmental offences, enforcement, penalties and defences

  7. NSLS 2006 ACTIVITY REPORT (NATIONAL SYNCHROTRON LIGHT SOURCE ACTIVITY REPORT 2006)

    International Nuclear Information System (INIS)

    MILLER, L.

    2006-01-01

    This past year has seen both challenges and fantastic new opportunities for the user community at the NSLS. The fantastic new opportunities are clear and abundant. We now have a five-year strategic plan for new development and continued operation of the NSLS. The NSLS continues to be an extremely productive facility, and the UEC is delighted at how NSLS Chair Chi-Chang Kao has consulted widely within the user community to develop a five-year plan for strategic upgrades and continued operation of the facility. The NSLS-II project, led by Associate Lab Director Steve Dierker, has done very well in its Department of Energy (DOE) reviews and will hopefully soon receive Critical Decision-1 (CD-1) approval, which in DOE lingo gives a go-ahead to launch the detailed design of the facility. We also held the first joint user meeting between the NSLS and Brookhaven's Center for Functional Nanomaterials (CFN), for which the building is near completion. The joint user meeting is an important step toward the close collaboration of the two facilities. The CFN, led by Emilio Mendez, promises to provide capabilities and research foci that are complementary to those at the NSLS. Together, all of these developments give a clear path to an exciting future of synchrotron radiation research at Brookhaven. However, with opportunities come challenges. One of the largest of these faced in the past year involved congressional support for scientific research in general, and DOE user facilities in particular. As you likely know, Congress did not complete its usual budget process in 2006, with the exceptions of the departments of Defense and Homeland Security. This left science funding at the budget levels enacted in late 2005 for FY2006, and unfortunately, FY2006 was not a particularly memorable vintage for science support. The good news is that you, the user community, have spoken up with unprecedented vigor about this, and Congress appears to be listening. As we look at the FY2007 budget

  8. NSLS 2006 ACTIVITY REPORT (NATIONAL SYNCHROTRON LIGHT SOURCE ACTIVITY REPORT 2006)

    Energy Technology Data Exchange (ETDEWEB)

    MILLER, L. (EDITOR)

    2006-12-31

    This past year has seen both challenges and fantastic new opportunities for the user community at the NSLS. The fantastic new opportunities are clear and abundant. We now have a five-year strategic plan for new development and continued operation of the NSLS. The NSLS continues to be an extremely productive facility, and the UEC is delighted at how NSLS Chair Chi-Chang Kao has consulted widely within the user community to develop a five-year plan for strategic upgrades and continued operation of the facility. The NSLS-II project, led by Associate Lab Director Steve Dierker, has done very well in its Department of Energy (DOE) reviews and will hopefully soon receive Critical Decision-1 (CD-1) approval, which in DOE lingo gives a go-ahead to launch the detailed design of the facility. We also held the first joint user meeting between the NSLS and Brookhaven's Center for Functional Nanomaterials (CFN), for which the building is near completion. The joint user meeting is an important step toward the close collaboration of the two facilities. The CFN, led by Emilio Mendez, promises to provide capabilities and research foci that are complementary to those at the NSLS. Together, all of these developments give a clear path to an exciting future of synchrotron radiation research at Brookhaven! However, with opportunities come challenges! One of the largest of these faced in the past year involved congressional support for scientific research in general, and DOE user facilities in particular. As you likely know, Congress did not complete its usual budget process in 2006, with the exceptions of the departments of Defense and Homeland Security. This left science funding at the budget levels enacted in late 2005 for FY2006, and unfortunately, FY2006 was not a particularly memorable vintage for science support. The good news is that you, the user community, have spoken up with unprecedented vigor about this, and Congress appears to be listening. As we look at the FY2007

  9. The Arabidopsis Transcription Factor MYB112 Promotes Anthocyanin Formation during Salinity and under High Light Stress1[OPEN

    Science.gov (United States)

    Lotkowska, Magda E.; Tohge, Takayuki; Fernie, Alisdair R.; Xue, Gang-Ping; Balazadeh, Salma; Mueller-Roeber, Bernd

    2015-01-01

    MYB transcription factors (TFs) are important regulators of flavonoid biosynthesis in plants. Here, we report MYB112 as a formerly unknown regulator of anthocyanin accumulation in Arabidopsis (Arabidopsis thaliana). Expression profiling after chemically induced overexpression of MYB112 identified 28 up- and 28 down-regulated genes 5 h after inducer treatment, including MYB7 and MYB32, which are both induced. In addition, upon extended induction, MYB112 also positively affects the expression of PRODUCTION OF ANTHOCYANIN PIGMENT1, a key TF of anthocyanin biosynthesis, but acts negatively toward MYB12 and MYB111, which both control flavonol biosynthesis. MYB112 binds to an 8-bp DNA fragment containing the core sequence (A/T/G)(A/C)CC(A/T)(A/G/T)(A/C)(T/C). By electrophoretic mobility shift assay and chromatin immunoprecipitation coupled to quantitative polymerase chain reaction, we show that MYB112 binds in vitro and in vivo to MYB7 and MYB32 promoters, revealing them as direct downstream target genes. We further show that MYB112 expression is up-regulated by salinity and high light stress, environmental parameters that both require the MYB112 TF for anthocyanin accumulation under these stresses. In contrast to several other MYB TFs affecting anthocyanin biosynthesis, MYB112 expression is not controlled by nitrogen limitation or an excess of carbon. Thus, MYB112 constitutes a regulator that promotes anthocyanin accumulation under abiotic stress conditions. PMID:26378103

  10. Carbon trends. March 2006

    International Nuclear Information System (INIS)

    2006-03-01

    This newsletter makes a monthly synthesis of the European CO 2 market: traded volumes, spot prices, conformability of facilities, supply and demand, climate indexes (temperature, precipitations from March 2005 to February 2006), economic activity indicators (industrial production from December 2004 to December 2005), confidence index of business leaders (from February 2005 to February 2006), changes in energy prices (from March 2005 to February 2006), CO 2 quotas allocated to European Union countries and detailed indicators of CO 2 market, climate, economic activity and energy prices. (J.S.)

  11. 40 CFR 112.6 - Qualified Facilities Plan Requirements.

    Science.gov (United States)

    2010-07-01

    ... locate mobile or portable oil storage containers to prevent a discharge as described in § 112.1(b). (iii...). Construct all bulk storage container installations (except mobile refuelers and other non-transportation-related tank trucks), including mobile or portable oil storage containers, so that you provide a secondary...

  12. 15 CFR 930.112 - Request for Secretarial mediation.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Request for Secretarial mediation. 930... RESOURCE MANAGEMENT FEDERAL CONSISTENCY WITH APPROVED COASTAL MANAGEMENT PROGRAMS Secretarial Mediation § 930.112 Request for Secretarial mediation. (a) The Secretary or other head of a Federal agency, or the...

  13. Prevalence and Nature of Hearing Loss in 22q11.2 Deletion Syndrome

    Science.gov (United States)

    Van Eynde, Charlotte; Swillen, Ann; Lambeens, Elien; Verhaert, Nicolas; Desloovere, Christian; Luts, Heleen; Vander Poorten, Vincent; Devriendt, Koenraad; Hens, Greet

    2016-01-01

    Purpose: The purpose of this study was to clarify the prevalence, type, severity, and age-dependency of hearing loss in 22q11.2 deletion syndrome. Method: Extensive audiological measurements were conducted in 40 persons with proven 22q11.2 deletion (aged 6-36 years). Besides air and bone conduction thresholds in the frequency range between 0.125…

  14. Construction of radiation-reduced hybrids and their use in mapping of microclones from chromosome 10p11.2-q11.2

    International Nuclear Information System (INIS)

    Fujita, Shoichi; Shin, Eisei; Nakamura, Tsutomu; Kurahashi, Hiroki; Mori, Takesada; Takai, Shin-ichiro; Nishisho, Isamu; Kaneda, Yasufumi; Tanaka, Kiyoji.

    1993-01-01

    Radiation-reduced hybrids for mapping of DNA markers in the pericentromeric region of chromosome 10 were developed. A Chinese hamster/human somatic cell hybrid (762-8A) carrying chromosomes 10 and Y as the only human material were exposed to 40,000 rads of irradiation and then rescued by fusion with non-irradiated recipient Chinese hamster cells (GM459). Southern hybridization analyses revealed that 10 of 128 HAT-resistant clones contained human chromosomal fragments corresponding to at least one marker locus between FNRB (10p11.2) and RBP3 (10q11.2). These hybrids were then used to map microdissection clones previously isolated and roughly mapped to this chromosomal region by fluorescence in situ hybridization (FISH). Two of the six microclones studies could be mapped to the proximity of the D10S102 locus. These radiation hybrids are useful for the construction of refined genetic maps of the pericentromeric region of chromosome 10. (author) 50 refs

  15. Clinicopathologic Characteristics and Prognosis of Xp11.2 Translocation Renal Cell Carcinoma: Multicenter, Propensity Score Matching Analysis.

    Science.gov (United States)

    Choo, Min Soo; Jeong, Chang Wook; Song, Cheryn; Jeon, Hwang Gyun; Seo, Seong Il; Hong, Sung Kyu; Byun, Seok-Soo; Chung, Jin Soo; Hong, Sung-Hoo; Hwang, Eu Chang; Kim, Hyeon Hoe; Kwak, Cheol

    2017-10-01

    We evaluated the clinicopathologic characteristics and prognosis of Xp11.2 translocation (Xp11.2t) renal cell carcinoma (RCC) from a multicenter study and compare them with clear-cell RCC using a propensity score matching analysis. Between 2004 and 2013, 8384 consecutive patients from 7 institutions who were diagnosed with RCC were reviewed, and the pathologically confirmed Xp11.2t cases were enrolled. The oncological outcomes of Xp11.2t were compared with those of clear-cell RCC by selecting matched cases using 1:3 propensity score matching methods in a precollected clear-cell RCC data set from our hospital. The patients were divided into 2 subgroups on the basis of age of onset, either before (early) or after (late) 45 years old. Xp11.2t was found in 61 cases, corresponding to 0.72% of RCC cases for the 10 years. The mean age was 38.2 ± 19.4 years, and the mean tumor size was 6.2 ± 3.9 cm. The Xp11.2t cases were at more advanced stages and showed tendencies to involve lymph nodes at diagnosis. After the matching, there were no significant differences in recurrence-free and overall survival compared with clear-cell RCC. The age of incidence for Xp11.2t had a bimodal distribution, which was most common in the 30s and smaller peak in the 60s. Xp11.2t corresponded to a significantly worse prognosis for overall survival in late onset (after 45 years) subgroup (P = .038; hazard ratio, 3.199; 95% confidence interval, 1.065-9.609). This neoplasm has more aggressive clinicopathologic features at diagnosis. In older patients with onset age > 45 years, Xp11.2t showed a significantly worse prognosis than clear-cell RCC. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. End-of-year closure 2006/2007

    CERN Document Server

    HR Department

    2006-01-01

    As announced in Weekly Bulletin No. 3-4/2006, the Laboratory will be closed from Saturday 23 December 2006 to Sunday 7 January 2007 inclusive. This period consists of 16 days: 4 days' official holiday, i.e. 24, 25 and 31 December 2006, and 1 January 2007; 2 days, 26 December 2006 to compensate for 24 December 2006, and 2 January 2007 to compensate for 31 December 2006 (Article R II 4.33 of the Staff Regulations); 6 days' special paid leave in accordance with Article R II 4.34 of the Staff Regulations, i.e. 27, 28 and 29 December 2006, and 3, 4 and 5 January 2007; 3 Saturdays, i.e. 23 and 30 December 2006, and 6 January 2007; 1 Sunday, i.e. 7 January 2007. The first working day in the New Year will be Monday 8 January 2007. Further information is available from Department Secretariats, specifically concerning the conditions applicable to members of the personnel who are required to work during this period. Human Resources Department Tel. 73903

  17. Cognitive behavioral therapy in 22q11.2 microdeletion with psychotic symptoms: What do we learn from schizophrenia?

    Science.gov (United States)

    Demily, Caroline; Franck, Nicolas

    2016-11-01

    The 22q11.2 deletion syndrome (22q11.2DS) is one of the most common microdeletion syndromes, with a widely underestimated prevalence between 1 per 2000 and 1 per 6000. Since childhood, patients with 22q11.2DS are described as having difficulties to initiate and maintain peer relationships. This lack of social skills has been linked to attention deficits/hyperactivity disorder, anxiety and depression. A high incidence of psychosis and positive symptoms is observed in patients with 22q11.2DS and remains correlated with poor social functioning, anxiety and depressive symptoms. Because 22q11.2DS and schizophrenia share several major clinical features, 22q11.2DS is sometimes considered as a genetic model for schizophrenia. Surprisingly, almost no study suggests the use of cognitive and behavioral therapy (CBT) in this indication. We reviewed what should be learned from schizophrenia to develop specific intervention for 22q11.2DS. In our opinion, the first step of CBT approach in 22q11.2DS with psychotic symptoms is to identify precisely which tools can be used among the already available ones. Cognitive behavioral therapy (CBT) targets integrated disorders, i.e. reasoning biases and behavior disorders. In 22q11.2DS, CBT-targeted behavior disorders may take the form of social avoidance and withdrawal or, in the contrary, a more unusual disinhibition and aggressiveness. In our experience, other negative symptoms observed in 22q11.2DS, such as motivation deficit or anhedonia, may also be reduced by CBT. Controlled trials have been studying the benefits of CBT in schizophrenia and several meta-analyses proved its effectiveness. Therefore, it is legitimate to propose this tool in 22q11.2DS, considering symptoms similarities. Overall, CBT is the most effective psychosocial intervention on psychotic symptoms and remains a relevant complement to pharmacological treatments such as antipsychotics. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  18. Impact of Childbearing Decisions on Family Size of Korean Women with Systemic Lupus Erythematosus.

    Science.gov (United States)

    Kim, In Je; Kim, Hyoun-Ah; Suh, Chang-Hee; Park, Yong-Wook; Lee, Hye-Soon; Bang, So-Young; Bae, Sang-Cheol; Kang, Young Mo; Lee, Won Kyung; Park, Hyesook; Lee, Jisoo

    2016-05-01

    Systemic lupus erythematosus (SLE) predominantly affects women in their reproductive years and has a significant impact on childbearing. We investigated the influence of personal decision on family size among Korean women with SLE and factors that affect the decisions. A case-control study comparing childbearing history and decisions of 112 SLE patients and 135 controls was performed. Women with SLE participating in the Network for Lupus Clinical Research in South Korea and matching controls between ages of 18-45, who are/were married or living with a partner were included. Data regarding socio-demographics, reproductive history, and childbearing decisions were collected through a survey using a standardized questionnaire and medical record review. More women with SLE reported at least one pregnancy (85.7% vs. 71.9%, P = 0.009) or at least one live birth (85.7% vs. 71.9%, P = 0.003) compared with controls. Mean number of pregnancies was significantly higher (2.4 ± 1.6 vs. 1.4 ± 1.3, P family size and childbearing decisions among Korean women with SLE.

  19. Repeat Syphilis Among Men Who Have Sex With Men in California, 2002–2006: Implications for Syphilis Elimination Efforts

    Science.gov (United States)

    Chew Ng, Rilene A.; Katz, Kenneth A.; Bernstein, Kyle T.; Samuel, Michael C.; Kerndt, Peter R.; Bolan, Gail

    2012-01-01

    Objectives. We examined rates of and risk factors for repeat syphilis infection among men who have sex with men (MSM) in California. Methods. We analyzed 2002 to 2006 California syphilis surveillance system data. Results. During the study period, a mean of 5.9% (range: 4.9%–7.1% per year) of MSM had a repeat primary or secondary (PS) syphilis infection within 2 years of an initial infection. There was no significant increase in the annual proportion of MSM with a repeat syphilis infection (P = .42). In a multivariable model, factors associated with repeat syphilis infection were HIV infection (odds ratio [OR] = 1.65; 95% confidence interval [CI] = 1.14, 2.37), Black race (OR = 1.84; 95% CI = 1.12, 3.04), and 10 or more recent sex partners (OR = 1.99; 95% CI = 1.12, 3.50). Conclusions. Approximately 6% of MSM in California have a repeat PS syphilis infection within 2 years of an initial infection. HIV infection, Black race, and having multiple sex partners are associated with increased odds of repeat infection. Syphilis elimination efforts should include messages about the risk for repeat infection and the importance of follow-up testing. Public health attention to individuals repeatedly infected with syphilis may help reduce local disease burdens. PMID:22095364

  20. Single-particle states in ^112Cd probed with the ^111Cd(d,p) reaction

    Science.gov (United States)

    Garrett, P. E.; Jamieson, D.; Demand, G. A.; Finlay, P.; Green, K. L.; Leach, K. G.; Phillips, A. A.; Sumithrarachchi, C. S.; Svensson, C. E.; Triambak, S.; Wong, J.; Ball, G. C.; Hertenberger, R.; Wirth, H.-F.; Kr"Ucken, R.; Faestermann, T.

    2009-10-01

    As part of a program of detailed spectroscopy of the Cd isotopes, the single-particle neutron states in ^112Cd have been probed with the ^111Cd(d,p) reaction. Beams of polarized 22 MeV deuterons, obtained from the LMU/TUM Tandem Accelerator, bombarded a target of ^111Cd. The protons from the reaction, corresponding to excitation energies up to 3 MeV in ^112Cd, were momentum analyzed with the Q3D spectrograph. Cross sections and analyzing powers were fit to results of DWBA calculations, and spectroscopic factors were determined. The results from the experiment, and implications for the structure of ^112Cd, will be presented.

  1. 10 CFR 60.112 - Overall system performance objective for the geologic repository after permanent closure.

    Science.gov (United States)

    2010-01-01

    ... repository after permanent closure. 60.112 Section 60.112 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Technical Criteria Performance... environment following permanent closure conform to such generally applicable environmental standards for...

  2. Evaluation of 22q11.2 deletion in Cleft Palate patients

    Science.gov (United States)

    Prabodha, L. B. Lahiru; Dias, Dayanath Kumara; Nanayakkara, B. Ganananda; de Silva, Deepthi C.; Chandrasekharan, N. Vishvanath; Ileyperuma, Isurani

    2012-01-01

    Background: Cleft palate is the commonest multifactorial epigenetic disorder with a prevalence of 0.43-2.45 per 1000. The objectives of this study were to evaluate the clinical features and identify the 22q11.2 deletion in patients with cleft palate in Sri Lanka. Materials and Methods: Cleft patients attending a Teaching Hospital in Sri Lanka were recruited for this study. The relevant data were obtained from review of case notes, interviews, and examination of patients according to a standard evaluation sheet. Quantitative multiplex polymerase chain reaction (PCR) was performed to identify the 22q11.2 deletion. A gel documentation system (Bio-Doc) was used to quantify the PCR product following electrophoresis on 0.8% agarose gel. Results and Conclusion: There were 162 cleft palate patients of whom 59% were females. A total of 92 cleft palate subjects (56.2%) had other associated clinical features. Dysmorphic features (25.27%) and developmental delays (25.27%) were the commonest medical problems encountered. The cleft was limited to the soft palate in 125 patients, while in 25 patients it involved both the hard and the soft palate. There were seven subjects with bifid uvula and five subjects with submucous cleft palate. None of the patients had 22q11.2 deletion in this study population. A multicentered large population-based study is needed to confirm the results of this study and to develop guidelines on the appropriate use of 22q11.2 deletion testing, which are valid for cleft palate patients in Sri Lanka. PMID:23483617

  3. Fluency aspects of oral narrative task in del22q11.2 syndrome.

    Science.gov (United States)

    Santos, Amanda Oliveira; Rossi, Natalia Freitas; Tandel, Maria da Conceição Faria Freitas; Richieri-Costa, Antonio; Giacheti, Célia Maria

    2016-01-01

    To investigate the fluency aspects of the oral narrative task in individuals with del22q11.2 syndrome and compare them with those of individuals with typical language development. Fifteen individuals diagnosed with del22q11.2 syndrome, both genders, aged 7-17 years participated in this study. They were compared with 15 individuals with typical language development, with similar gender and chronological age profiles. The oral narrative was elicited using the book "Frog, Where Are You?", and the fluency aspects were analyzed according to speech rate and type and frequency of disfluency (typical and stuttering). The number and duration of pauses were also investigated. The data were statistically analyzed. The group with del22q11.2 syndrome showed a higher average when compared with the group without the syndrome for the percentage of typical disfluencies, mainly hesitation and revision. The group presenting the syndrome also showed a higher average for stuttering disfluencies, with pause as the most frequent disfluency. With respect to speech rate, the group with the syndrome presented a lower average for the number of words and syllables per minute. Individuals with del22q11.2 syndrome showed greater difficulties of narration than their peers. The fluency aspects of the oral narrative task in subjects with del22q11.2 syndrome were similar to those of individuals with typical language development regarding the presence of hesitation, revision, and pause, but they were different with respect to frequency of disfluency, which was higher in individuals with the syndrome.

  4. 22q11.2 deletion carriers and schizophrenia-associated novel variants.

    Science.gov (United States)

    Balan, S; Iwayama, Y; Toyota, T; Toyoshima, M; Maekawa, M; Yoshikawa, T

    2014-01-01

    The penetrance of schizophrenia risk in carriers of the 22q11.2 deletion is high but incomplete, suggesting the possibility of additional genetic defects. We performed whole exome sequencing on two individuals with 22q11.2 deletion, one with schizophrenia and the other who was psychosis-free. The results revealed novel genetic variants related to neuronal function exclusively in the person with schizophrenia (frameshift: KAT8, APOH and SNX31; nonsense: EFCAB11 and CLVS2). This study paves the way towards a more complete understanding of variant dose and genetic architecture in schizophrenia.

  5. Perspectives for deep geological formation disposal research in France beyond 2006

    International Nuclear Information System (INIS)

    Landais, P.

    2006-01-01

    One finalised aim underlies research conducted on the feasibility of geological disposal: the possibility of having a reversible disposal system available. A model has been drawn up to provide a framework for the analysis and propose possible research content between 2006 and 2015. This period will correspond to the move from the feasibility to a development, optimisation and detailed study phase. It aims at answering any questions raised by reviewers and develops forward the study of a repository. It will also correspond to the consolidation of scientific data, greater understanding of certain mechanisms and an approach of scientific and technical integration. Another goal of the period 2006-2015 would be to collect elements for a decision on the sitting issue through an extended survey. This phase of development includes confirmation of the data acquired during the previous phase and over relatively long periods, optimisation of repository concepts and detailed study of their main components, the production of full-scale mock-ups or simulations to validate the main technological design points and refining of data extrapolation methods. (author)

  6. Veemajandus, 2006 = Water management, 2006 / Kadi Siimer

    Index Scriptorium Estoniae

    Siimer, Kadi

    2007-01-01

    Eestis võeti 2006. aastal kõigist veeallikatest kokku 1,6 miljardit kuupmeetrit vett, tekkinud heitveest vajas puhastamist 264 miljonit kuupmeetrit, võrreldes 2005. aastaga vähenes 2 protsenti loodusesse juhitud heitvee orgaaniliste ainete reostuskoormus. Graafikud. Diagramm. Tabelid

  7. Learning from examples - Generation and evaluation of decision trees for software resource analysis

    Science.gov (United States)

    Selby, Richard W.; Porter, Adam A.

    1988-01-01

    A general solution method for the automatic generation of decision (or classification) trees is investigated. The approach is to provide insights through in-depth empirical characterization and evaluation of decision trees for software resource data analysis. The trees identify classes of objects (software modules) that had high development effort. Sixteen software systems ranging from 3,000 to 112,000 source lines were selected for analysis from a NASA production environment. The collection and analysis of 74 attributes (or metrics), for over 4,700 objects, captured information about the development effort, faults, changes, design style, and implementation style. A total of 9,600 decision trees were automatically generated and evaluated. The trees correctly identified 79.3 percent of the software modules that had high development effort or faults, and the trees generated from the best parameter combinations correctly identified 88.4 percent of the modules on the average.

  8. The structure of 112In nuclear isomers and their interaction with extranuclear fields

    International Nuclear Information System (INIS)

    Ionescu-Bujor, M.

    1979-01-01

    Research on the structure of short life-time isomeric states of 112 In and their interaction with extranuclear fields is presented. Isomeric states have been populated in reactions 112 Cd(p,n), 109 Ag(α,n) and 112 Cd(d,2n) using the pulsated beam method. The results of the studies performed can be summarized as it follows: I. Nuclear structure. In the case of 112 In, there are two isomeric states having Jsup(π)=8 - (Tsub(1/2)=2.81.μs) and Jsup(π)=6 + (Tsub(1/2)=0.69.μs) and excitation energies of 606,0 KeV. The desintegration procedure schematically represented of the new isomeric states is: 8 - (262.7 KeV - M2) 6 + (187.8 KeV - E2)4 + . The magnetic momenta of the isomeric states are: π(8 - )-3.03+-0.03 m.n. μ(6 + )-4.05+-0.04 m.n. The quadripolar electric momentum of the 8 - isomeric state is: [Q(8 - )] = 0.093 +- 0.006 b. The 8 - isomeric state stands for the minimum energy level of the multiplet generated by the [π(lgsub(9/2))ν(1hsub(11/2))] configuration. The 6 + isomeric state was described by a mixture of configurations resulting from coupling the lgsub(9/2) proton state with the 2dsub(5/2), 2dsub(3/2) and lgsub(7/2) neutron states. II. Population sections. In studying the relations of isomeric sections into double even isotopes sup(110-116)In, excited in (p,n) reactions, a very high population of the 8 - isomeric states is pointed out, on condition that the positive parity isomeric states were satisfactorily described in the statistical model. The anomaly observed in the population of states 8 - can be explained by the influence of the selection rule after γ upon transitions γ, which confirm the existence of the multiplet of levels generated by the [π(lgsub(9/2))ν(1hsub(11/2))] pure configuration in these nuclei. III. Examination of effects induced by irradiation defects in the InAg system. The short life-time isomeric states of 112 In, excited in reaction 109 (α,n), were used in the study of hyperfine interactions by means of the method of

  9. Avaliku sektori kulutused keskkonnakaitsele, 2006 = Environmental protection expenditure of public sector, 2006 / Kersti Salu

    Index Scriptorium Estoniae

    Salu, Kersti

    2008-01-01

    Keskvalitsus kulutas 2006. aastal 2,2 miljardit krooni keskkonnakaitsele, kohalikud omavalitsused 339 miljonit krooni ning Keskkonnainvesteeringute Keskuse keskkonnaprojektide kogumaksumus oli 2006. aastal ligikaudu 600 miljonit krooni. Tabelid. Diagramm

  10. 38 CFR 3.112 - Fractions of one cent.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Fractions of one cent. 3... Pension, Compensation, and Dependency and Indemnity Compensation Administrative § 3.112 Fractions of one cent. In all cases where the amount to be paid under any award involves a fraction of a cent, the...

  11. Autism Spectrum Disorder, Developmental and Psychiatric Features in 16p11.2 Duplication.

    Science.gov (United States)

    Green Snyder, LeeAnne; D'Angelo, Debra; Chen, Qixuan; Bernier, Raphael; Goin-Kochel, Robin P; Wallace, Arianne Stevens; Gerdts, Jennifer; Kanne, Stephen; Berry, Leandra; Blaskey, Lisa; Kuschner, Emily; Roberts, Timothy; Sherr, Elliot; Martin, Christa L; Ledbetter, David H; Spiro, John E; Chung, Wendy K; Hanson, Ellen

    2016-08-01

    The 16p11.2 duplication (BP4-BP5) is associated with Autism Spectrum Disorder (ASD), although significant heterogeneity exists. Quantitative ASD, behavioral and neuropsychological measures and DSM-IV diagnoses in child and adult carriers were compared with familial non-carrier controls, and to published results from deletion carriers. The 16p11.2 duplication phenotype ranges widely from asymptomatic presentation to significant disability. The most common diagnoses were intellectual disability, motor delays and Attention Deficit Hyperactivity Disorder in children, and anxiety in adults. ASD occurred in nearly 20 % of child cases, but a majority of carriers did not show the unique social features of ASD. The 16p11.2 duplication phenotype is characterized by wider variability than the reciprocal deletion, likely reflecting contributions from additional risk factors.

  12. CERN Technical Training 2006: ANSYS Course Sessions (August-September 2006)

    CERN Multimedia

    2006-01-01

    The following ANSYS course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2006, and in collaboration with CAD-FEM AG (CH): ANSYS Design Modeler (course in French): 29-30.8.2006 (2 days) ANSYS Workbench (course in French): 12-15.9.2006 (4 days, only 2 places available) If you are interested in attending any of the above course sessions, please discuss with your supervisor and/or your DTO, and apply electronically via EDH from the course description pages that can be found at under "Upcoming course sessions", with the detailed course programmes. The complete training offer of ANSYS courses at CERN can be found at the same website, under the Mechanical Design curriculum. CERN Technical Training courses are open only to the members of CERN personnel (staff members and fellows; associates, students, users, project associates; apprentices: employees of CERN contractors, with some restrictions). In particular, quoted prices and programmes refer specifically to the CERN ...

  13. ANDRA, 2006 activity report; ANDRA, Rapport d'activite 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The French national agency of radioactive waste management (ANDRA) was marked in 2006 by two outstanding events: the publication of the national inventory of radioactive wastes and valorisable materials, and the vote of the law from June 28, 2006 relative to the sustainable management of radioactive wastes and materials. This road-map law has an impact on ANDRA's activities for the coming years. This activity report presents several 2006 highlights of ANDRA's missions as well: the public service mission, the by-law about the effluents of the Aube plant for the storage of low-medium activity wastes, the building of the first 'double-cell' at the very-low activity waste storage plant of Aube, the research studies about the project of deep underground disposal of high-medium activity, long-living wastes, and the public information about ANDRA's technical and scientific know-how. The management and financial reports are attached in appendix. (J.S.)

  14. 2016 Annual Scientific Meeting of EUBS

    Science.gov (United States)

    2016-12-23

    Geneva, Switzerland), discussing, among others, the pharmacological effects of slight to moderate hyperoxygenation (such as in the use of hyperbaric air...34 HBO and neuroscience". i. Hadanny et al. (Tel Aviv, Israel) showed F- MRI results, coupled with cognitive function measurements (Neurotrax software...treated from 2004 to 2013, they concluded in a high efficacy of HBOT both in Visual Analogue Scoring (VAS) and MRI analysis (improvement of 90.9% in

  15. Automated Decision Tree Classification of Corneal Shape

    Science.gov (United States)

    Twa, Michael D.; Parthasarathy, Srinivasan; Roberts, Cynthia; Mahmoud, Ashraf M.; Raasch, Thomas W.; Bullimore, Mark A.

    2011-01-01

    Purpose The volume and complexity of data produced during videokeratography examinations present a challenge of interpretation. As a consequence, results are often analyzed qualitatively by subjective pattern recognition or reduced to comparisons of summary indices. We describe the application of decision tree induction, an automated machine learning classification method, to discriminate between normal and keratoconic corneal shapes in an objective and quantitative way. We then compared this method with other known classification methods. Methods The corneal surface was modeled with a seventh-order Zernike polynomial for 132 normal eyes of 92 subjects and 112 eyes of 71 subjects diagnosed with keratoconus. A decision tree classifier was induced using the C4.5 algorithm, and its classification performance was compared with the modified Rabinowitz–McDonnell index, Schwiegerling’s Z3 index (Z3), Keratoconus Prediction Index (KPI), KISA%, and Cone Location and Magnitude Index using recommended classification thresholds for each method. We also evaluated the area under the receiver operator characteristic (ROC) curve for each classification method. Results Our decision tree classifier performed equal to or better than the other classifiers tested: accuracy was 92% and the area under the ROC curve was 0.97. Our decision tree classifier reduced the information needed to distinguish between normal and keratoconus eyes using four of 36 Zernike polynomial coefficients. The four surface features selected as classification attributes by the decision tree method were inferior elevation, greater sagittal depth, oblique toricity, and trefoil. Conclusions Automated decision tree classification of corneal shape through Zernike polynomials is an accurate quantitative method of classification that is interpretable and can be generated from any instrument platform capable of raw elevation data output. This method of pattern classification is extendable to other classification

  16. The NATO SOF Air Wing: A Basing Decision

    Science.gov (United States)

    2012-12-01

    11 Susan Hesse Owen & Mark S. Daskin , “Strategic Facility Location: A Review,” European Journal of Operational Research 111, (1998), 423. 6 the...Journal of Travel Research 45, (2006):167–174. Owen, Susan Hesse and Daskin , Mark S. “Strategic Facility Location: A Review.” European Journal of...WING: A BASING DECISION by James M. Cox December 2012 Thesis Advisor: William Fox Second Reader: Brian Greenshields THIS PAGE

  17. Scientific Literacy and Student Attitudes: Perspectives from PISA 2006 science

    Science.gov (United States)

    Bybee, Rodger; McCrae, Barry

    2011-01-01

    International assessments provide important knowledge about science education and help inform decisions about policies, programmes, and practices in participating countries. In 2006, science was the primary domain for the Programme for International Student Assessment (PISA), supported by the Organisation for Economic Cooperation and Development (OECD) and conducted by the Australian Council for Educational Research (ACER). Compared to the school curriculum orientation of Trends in International Math and Science Study (TIMSS), PISA provides a perspective that emphasises the application of knowledge to science and technology-related life situations. The orientation of PISA includes both knowledge and attitudes as these contribute to students' competencies that are central to scientific literacy. In addition to students' knowledge and competencies, the 2006 PISA survey gathered data on students' interest in science, support for scientific enquiry, and responsibility towards resources and environments. The survey used both a non-contextualised student questionnaire and contextualised questions. The latter is an innovative approach which embedded attitudinal questions at the conclusion of about two-thirds of the test units. The results presented in this article make connections between students' attitudes and interests in science and scientific literacy.

  18. Eesti loomakasvatus 2006. aastal / Matti Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Matti, 1947-

    2007-01-01

    Eesti Statistikaameti ning Põllumajandusministeeriumi koostatud 2006. aasta loomakasvatuse andmete analüüs. Tabelid: Loomade ja lindude arv seisuga 31. detsember; Lihatoodang elusmassis 2005. ja 2006. aastal; Prognoositav lihatoodang tapamassis 2005. ja 2006. aastal

  19. Algorithm Theory - SWAT 2006

    DEFF Research Database (Denmark)

    This book constitutes the refereed proceedings of the 10th Scandinavian Workshop on Algorithm Theory, SWAT 2006, held in Riga, Latvia, in July 2006. The 36 revised full papers presented together with 3 invited papers were carefully reviewed and selected from 154 submissions. The papers address all...

  20. Physiology and transcriptomics of water-deficit stress responses in wheat cultivars TAM 111 and TAM 112.

    Science.gov (United States)

    Reddy, Srirama Krishna; Liu, Shuyu; Rudd, Jackie C; Xue, Qingwu; Payton, Paxton; Finlayson, Scott A; Mahan, James; Akhunova, Alina; Holalu, Srinidhi V; Lu, Nanyan

    2014-09-01

    Hard red winter wheat crops on the U.S. Southern Great Plains often experience moderate to severe drought stress, especially during the grain filling stage, resulting in significant yield losses. Cultivars TAM 111 and TAM 112 are widely cultivated in the region, share parentage and showed superior but distinct adaption mechanisms under water-deficit (WD) conditions. Nevertheless, the physiological and molecular basis of their adaptation remains unknown. A greenhouse study was conducted to understand the differences in the physiological and transcriptomic responses of TAM 111 and TAM 112 to WD stress. Whole-plant data indicated that TAM 112 used more water, produced more biomass and grain yield under WD compared to TAM 111. Leaf-level data at the grain filling stage indicated that TAM 112 had elevated abscisic acid (ABA) content and reduced stomatal conductance and photosynthesis as compared to TAM 111. Sustained WD during the grain filling stage also resulted in greater flag leaf transcriptome changes in TAM 112 than TAM 111. Transcripts associated with photosynthesis, carbohydrate metabolism, phytohormone metabolism, and other dehydration responses were uniquely regulated between cultivars. These results suggested a differential role for ABA in regulating physiological and transcriptomic changes associated with WD stress and potential involvement in the superior adaptation and yield of TAM 112. Copyright © 2014 Elsevier GmbH. All rights reserved.

  1. Study of intruder band in {sup 112}Sn

    Energy Technology Data Exchange (ETDEWEB)

    Ganguly, S. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Banerjee, P. [Saha Institute of Nuclear Physics, Kolkata 700064 (India)]. E-mail: polash.banerjee@saha.ac.in; Ray, I. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Kshetri, R. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Raut, R. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Bhattacharya, S. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Saha-Sarkar, M. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Goswami, A. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Mukhopadhyay, S. [UGC-DAE-CSR, Kolkata 700098 (India); Mukherjee, A. [Saha Institute of Nuclear Physics, Kolkata 700064 (India); Mukherjee, G. [Variable Energy Cyclotron Centre, Kolkata 700064 (India); Basu, S.K. [Variable Energy Cyclotron Centre, Kolkata 700064 (India)

    2007-06-01

    Excited states of the positive-parity intruder band in {sup 112}Sn, populated in the {sup 100}Mo({sup 20}Ne,{alpha}4n) reaction at a beam energy of 136 MeV, have been studied. The band has been observed up to 11570.0 keV with spin (24{sup +}). Mean lifetimes have been measured for six states up to the 22{sup +}, 10335.1 keV level and an upper limit of the lifetime has been estimated for the 11570.0 keV (24{sup +}) state. The B(E2) values, derived from the present lifetime results, correspond to a moderate quadrupole deformation of {beta}{sub 2}{approx}0.18 for states with spin J{sup {pi}}>=12{sup +}, and the decrease in B(E2) for the 14{sup +}->12{sup +} transition is consistent with a {nu}(h{sub 11/2}){sup 2} alignment at {omega}{approx}0.35 MeV, predicted by a cranked shell-model calculation. Total Routhian surface calculations predict a triaxial shape following the alignment.

  2. Triaxial energy relation to describe rotational band in 98-112Ru nuclei

    International Nuclear Information System (INIS)

    Singh, Yuvraj; Gupta, K.K.; Bihari, Chhail; Varshney, A.K.; Varshney, Mani; Singh, M.; Gupta, D.K.

    2010-01-01

    In a broader perspective rotation vibration coupling parameter (b) is considered changing with the change in excitation energy (ε 1 ) and is evaluated on fitting experimental energy for 98-112 Ru isotopes in the frame work of general asymmetric rotor model. The moment of inertia parameter (a), common to yrast and quasi-γ band, is calculated from deformation parameter (β) using general empirical relation. The present work is undertaken to suggest some suitable equation for the trajectories which are similar in shape in 98-112 Ru nuclei

  3. CERN Technical Training 2006: Software and System Technologies Curriculum - Scheduled Course Sessions (October 2006-March 2007)

    CERN Multimedia

    2006-01-01

    The Software and System Technologies Curriculum of the CERN Technical Training Programme offers comprehensive training in C++, Java, Perl, Python, XML, OO programming, JCOP/PVSS, database design and Oracle. In the Oracle, C++, OO and Java course series there are some places available on the following course sessions, currently scheduled until March 2007: Object-Oriented Analysis and Design using UML: 17-19 October 2006 (3 days) JAVA - Level 1: 30 October - 1 November 2006 (3 days) C++ Programming Part 1 - Introduction to Object-Oriented Design and Programming: 14-16 November 2006 (3 days) Oracle Database Server Administration: 23-29 November 2007 (5 days) JAVA - Level 2: 4-7 December 2006 (4 days) C++ Programming Part 2 - Advanced C++ and its Traps and Pitfalls: 12-15 December 2006 (4 days) JAVA 2 Enterprise Edition - Part 2: Enterprise JavaBeans: 18-20 December 2006 (3 days) JAVA 2 Enterprise Edition - Part 1: Web Applications: 15-16 January 2007 (2 days) C++ Programming Part 3 - Templates and the STL (St...

  4. 22q11.2 Deletion Syndrome Is Associated With Impaired Auditory Steady-State Gamma Response

    DEFF Research Database (Denmark)

    Larsen, Kit Melissa; Pellegrino, Giovanni; Birknow, Michelle Rosgaard

    2017-01-01

    The 22q11.2 deletion syndrome confers a markedly increased risk for schizophrenia. 22q11.2 deletion carriers without manifest psychotic disorder offer the possibility to identify functional abnormalities that precede clinical onset. Since schizophrenia is associated with a reduced cortical gamma...

  5. Areva half-year report june 30, 2006; Areva rapport semestriel 30 juin 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document is the half-year financial report of the Areva group for 2006. It presents: 1 - Highlights of the period; 2 - Key data: Summary data, Segment reporting, Backlog, Income statement, Review by business division, Cash flow, Balance sheet data; 3 - Outlook; 4 - Events subsequent to the half-year end; 5 - Consolidated financial statements: Statutory auditors' report on the interim consolidated financial statements for the period January 1, 2006 to June 30, 2006, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of changes in equity, Segment reporting, Notes to the consolidated financial statements.

  6. Areva half-year report june 30, 2006; Areva rapport semestriel 30 juin 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document is the half-year financial report of the Areva group for 2006. It presents: 1 - Highlights of the period; 2 - Key data: Summary data, Segment reporting, Backlog, Income statement, Review by business division, Cash flow, Balance sheet data; 3 - Outlook; 4 - Events subsequent to the half-year end; 5 - Consolidated financial statements: Statutory auditors' report on the interim consolidated financial statements for the period January 1, 2006 to June 30, 2006, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of changes in equity, Segment reporting, Notes to the consolidated financial statements.

  7. Some notes on writing a commentary: Isaiah 1-12

    Directory of Open Access Journals (Sweden)

    A. Groenewald

    2009-07-01

    Full Text Available I was requested by the editors of the �Historical Commentary on the Old Testament� (HCOT to contribute two volumes on Isaiah in this series. This present article, however, focuses only on volume I: Isaiah 1-12. The aim of this article can be summarised in six points. Some introductory remarks are made with regard to the genre of commentary writing. Secondly, the viewpoint of the HCOT series is outlined; in other words its methodological and epistemological viewpoint. Thirdly, recent developments in the study of the book of Isaiah are discussed. Fourthly, my own objectives and hypothesis with regard to this project are outlined. Fifthly, a short overview of Isaiah 1-12 on a synchronic level is given. Sixthly, my research methodology is defined as a �diachronically reflected synchronic� reading of the Isaianic text. In the last section some concluding remarks are made.

  8. Paper or Plastic Revisited: Let's Keep Them Both--Reply to Broderick and Stone (2006); Tennen, Affleck, Coyne, Larsen, and DeLongis (2006); and Takarangi, Garry, and Loftus (2006)

    Science.gov (United States)

    Bolger, Niall; Shrout, Patrick E.; Green, Amie S.; Rafaeli, Eshkol; Reis, Harry T.

    2006-01-01

    The authors review commentaries by J. E. Broderick and A. A. Stone (2006); H. Tennen, G. Affleck, J. C. Coyne, R. J. Larsen, and A. DeLongis (2006); and M. K. T. Takarangi, M. Garry, and E. F. Loftus (2006) on their original article (A. S. Green, E. Rafaeli, N. Bolger, P. Shrout, & H. T. Reis, 2006). The authors were pleased to find more agreement…

  9. Entamoeba histolytica EhCP112 Dislocates and Degrades Claudin-1 and Claudin-2 at Tight Junctions of the Intestinal Epithelium

    Directory of Open Access Journals (Sweden)

    Patricia Cuellar

    2017-08-01

    Full Text Available During intestinal invasion, Entamoeba histolytica opens tight junctions (TJs reflected by transepithelial electrical resistance (TEER dropping. To explore the molecular mechanisms underlying this, we studied in vitro and in vivo the damage produced by the recombinant E. histolytica cysteine protease (rEhCP112 on TJ functions and proteins. rEhCP112 reduced TEER in Caco-2 cells in a dose- and time-dependent manner; and EhCP112-overexpressing trophozoites provoked major epithelial injury compared to control trophozoites. rEhCP112 penetrated through the intercellular space, and consequently the ion flux increased and the TJs fence function was disturbed. However, macromolecular flux was not altered. Functional in vitro assays revealed specific association of rEhCP112 with claudin-1 and claudin-2, that are both involved in regulating ion flux and fence function. Of note, rEhCP112 did not interact with occludin that is responsible for regulating macromolecular flux. Moreover, rEhCP112 degraded and delocalized claudin-1, thus affecting interepithelial adhesion. Concomitantly, expression of the leaky claudin-2 at TJ, first increased and then it was degraded. In vivo, rEhCP112 increased intestinal epithelial permeability in the mouse colon, likely due to apical erosion and claudin-1 and claudin-2 degradation. In conclusion, we provide evidence that EhCP112 causes epithelial dysfunction by specifically altering claudins at TJ. Thus, EhCP112 could be a potential target for therapeutic approaches against amoebiasis.

  10. EDF - 2006 full-year results, 2006 Financial report

    International Nuclear Information System (INIS)

    Gadonneix, Pierre

    2007-04-01

    As the world's biggest electricity generator, the EDF Group covers every sector of expertise, from generation to trading and transmission grids. EDF builds on the expertise of its people, its R and D and engineering skills, its experience as a leading industry operator and the attentive support of its customers to deliver competitive solutions that successfully reconcile economic growth with climate protection. This document presents the 2006 annual results and Consolidated financial statements of the Group at 31 December 2006: Consolidated income statements, Consolidated balance sheets, Consolidated cash flow statements, Changes in consolidated equity, Notes: Group accounting policies, Summary of accounting and valuation methods, Public distribution concessions in France, Comparability, Significant events and transactions of 2006 and 2005, Changes in the scope of consolidation, Segment reporting, Sales, Fuel and energy purchases, Other external expenses, Contractual obligations and commitments, Personnel expenses, Other operating income and expenses, Impairments / reversals, Other income and expenses, Financial result, Income taxes, Goodwill, Other intangible assets, Property, plant and equipment, Investments in companies accounted for under the equity method, Financial assets, Inventories including work-in-process, Trade receivables, Other receivables, Cash and cash equivalents, Held-for-sale assets and liabilities, Equity, Provisions, Special concession liabilities, Current and non-current financial liabilities, Derivatives, Other liabilities, Contribution of joint ventures, Related parties, Environment, Subsequent events, Transition to standards IAS 32 and 39 concerning financial instruments, Scope of consolidation

  11. Annual Report 2006

    International Nuclear Information System (INIS)

    Swiboda, G.

    2007-01-01

    The Annual Report of the Institute of Atomic Energy describes the results of the research activities carried out in 2006. The document consist of seven parts: General Information; Operation and safety of MARIA reactor; Radiation protection and dosimetry; Nuclear Technology in Energy Generation; Solid State Physics; Nuclear techniques in Health and Environment Protection management of Hazards and in last section the list of published in 2006 papers, conferences, seminars, workshops, research projects and educational activities are presented

  12. Annual Report 2006

    International Nuclear Information System (INIS)

    Chmielewska, D.; Infeld, E.; Zupranski, P.

    2007-06-01

    The ''Annual Report 2006'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2006. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute Grzegorz Wrochna is also given

  13. Annual Report 2006

    Energy Technology Data Exchange (ETDEWEB)

    Chmielewska, D; Infeld, E; Zupranski, P [The Andrzej Soltan Institute for Nuclear Studies, Swierk-Otwock (Poland)

    2007-06-15

    The ''Annual Report 2006'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2006. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute Grzegorz Wrochna is also given.

  14. Neonatal hypocalcemia, neonatal seizures, and intellectual disability in 22q11.2 deletion syndrome

    Science.gov (United States)

    Cheung, Evelyn Ning Man; George, Susan R.; Andrade, Danielle M.; Chow, Eva W. C.; Silversides, Candice K.; Bassett, Anne S.

    2015-01-01

    Purpose Hypocalcemia is a common endocrinological condition in 22q11.2 deletion syndrome. Neonatal hypocalcemia may affect neurodevelopment. We hypothesized that neonatal hypocalcemia would be associated with rare, more severe forms of intellectual disability in 22q11.2 deletion syndrome. Methods We used a logistic regression model to investigate potential predictors of intellectual disability severity, including neonatal hypocalcemia, neonatal seizures, and complex congenital heart disease, e.g., interrupted aortic arch, in 149 adults with 22q11.2 deletion syndrome. Ten subjects had moderate-to-severe intellectual disability. Results The model was highly significant (P < 0.0001), showing neonatal seizures (P = 0.0018) and neonatal hypocalcemia (P = 0.047) to be significant predictors of a more severe level of intellectual disability. Neonatal seizures were significantly associated with neonatal hypocalcemia in the entire sample (P < 0.0001), regardless of intellectual level. There was no evidence for the association of moderate- to-severe intellectual disability with other factors such as major structural brain malformations in this sample. Conclusion The results suggest that neonatal seizures may increase the risk for more severe intellectual deficits in 22q11.2 deletion syndrome, likely mediated by neonatal hypocalcemia. Neonatal hypocalcemia often remains unrecognized until the postseizure period, when damage to neurons may already have occurred. These findings support the importance of early recognition and treatment of neonatal hypocalcemia and potentially neonatal screening for 22q11.2 deletions. PMID:23765047

  15. User's manual for the upper Delaware River riverine environmental flow decision support system (REFDSS), Version 1.1.2

    Science.gov (United States)

    Talbert, Colin; Maloney, Kelly O.; Holmquist-Johnson, Chris; Hanson, Leanne

    2014-01-01

    Between 2002 and 2006, the Fort Collins Science Center (FORT) at the U.S. Geological Survey (USGS) conducted field surveys, organized workshops, and performed analysis of habitat for trout and shad in the Upper Delaware River Basin. This work culminated in the development of decision support system software (the Delaware River DSS–DRDSS, Bovee and others, 2007) that works in conjunction with the Delaware River Basin Commission’s reservoir operations model, OASIS, to facilitate comparison of the habitat and water-delivery effects of alternative operating scenarios for the Basin. This original DRDSS application was developed in Microsoft Excel and is available to all interested parties through the FORT web site (http://www.fort.usgs.gov/Products/Software/DRDSS/). Initial user feedback on the original Excel-based DSS highlighted the need for a more user-friendly and powerful interface to effectively deliver the complex data and analyses encapsulated in the DSS. In order to meet this need, the USGS FORT and Northern Appalachian Research Branch (NARB) developed an entirely new graphical user interface (GUI) application. Support for this research was through the DOI WaterSmart program (http://www.doi.gov/watersmart/html/index.php) of which the USGS component is the National Water Census (http://water.usgs.gov/watercensus/WaterSMART.html). The content and methodology of the new GUI interface emulates those of the original DSS with a few exceptions listed below. Refer to Bovee and others (2007) for the original information. Significant alterations to the original DSS include: • We moved from Excel-based data storage and processing to a more powerful database back end powered by SQLite. The most notable effect of this is that the previous maximum temporal extent of 10 years has been replaced by a dynamic extent that can now cover the entire period of record for which we have data (1928–2000). • We incorporated interactive geographic information system (GIS

  16. 2006 Homeland Security Symposium and Exposition. Held in Arlington, VA on 29-31 March 2006

    Science.gov (United States)

    2006-03-31

    Consequences , Vulnerabilities, and Threats) Prioritize Implement Protective Programs Measure Effectiveness 9March 2006 Major NIPP Theme: Sector Partnership... effect of exposure • Full understanding of the levels of exposure that mark the onset of miosis • Refined human operational exposure standard for GB...Untitled Document 2006 Homeland Security Symposium and Exposition.html[7/7/2016 11:38:26 AM] 2006 Homeland Security Symposium and Exposition

  17. The clinical presentation of attention deficit-hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome.

    Science.gov (United States)

    Niarchou, Maria; Martin, Joanna; Thapar, Anita; Owen, Michael J; van den Bree, Marianne B M

    2015-12-01

    Although attention deficit-hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder in children with 22q11.2DS, it remains unclear whether its clinical presentation is similar to that in children with idiopathic ADHD. The aim of this study is to compare the ADHD phenotype in children with and without 22q11.2DS by examining ADHD symptom scores, patterns of psychiatric comorbidity, IQ and gender distribution. Forty-four children with 22q11.2DS and ADHD (mean age = 9.6), 600 clinic children (mean age = 10.8) and 77 children with ADHD from a population cohort (mean age = 10.8) participated in the study. Psychopathology was assessed using parent-report research diagnostic instruments. There was a higher proportion of females in the 22q11.2DS ADHD sample in relation to the clinical sample (χ(2)  = 18.2, P ADHD inattentive subtype (χ(2)  = 114.76, P hyperactive-impulsive symptoms compared to the clinical group (z = 8.43, P ADHD group parents reported fewer oppositional defiant disorder/conduct disorder symptoms (z = 6.33, P disorder (χ(2)  = 4.56, P = 0.03) in relation to the clinical group. Two percent of the 22q11.2 DS ADHD sample had received ADHD treatment. The results were similar when the 22q11.2 ADHD group was compared to the population cohort ADHD group. The clinical presentation of ADHD and patterns of co-morbidity in 22q11.2DS is different from that in idiopathic ADHD. This could lead to clinical under-recognition of ADHD in this group. Examining psychopathology in 22q11.2DS can provide insights into the genetic origins of psychiatric problems with implications beyond the 22q11.2DS population. © 2015 Wiley Periodicals, Inc.

  18. PIRLS 2006

    DEFF Research Database (Denmark)

    Mejding, Jan; Rønberg, Louise

    PIRLS er en international læseundersøgelse af læsefærdigheder i 4. klasse. I alt 4000 danske elever fra hele landet deltog 2006 i undersøgelsen, som involverede elever fra 40 lande i verden. Denne sammenfatning gør i korte træk rede for hovedresultaterne i undersøgelsen.......PIRLS er en international læseundersøgelse af læsefærdigheder i 4. klasse. I alt 4000 danske elever fra hele landet deltog 2006 i undersøgelsen, som involverede elever fra 40 lande i verden. Denne sammenfatning gør i korte træk rede for hovedresultaterne i undersøgelsen....

  19. STS-112 Crew Interviews: Yurchikhin

    Science.gov (United States)

    2002-01-01

    A preflight interview with mission specialist Fyodor Yurchikhin is presented. He worked for a long time in Energia in the Russian Mission Control Center (MCC). Yurchikhin discusses the main goal of the STS-112 flight, which is to install the Integrated Truss Assembly S1 (Starboard Side Thermal Radiator Truss) on the International Space Station. He also talks about the three space walks required to install the S1. After the installation of S1, work with the bolts and cameras are performed. Yurchikhin is involved in working with nitrogen and ammonia jumpers. He expresses the complexity of his work, but says that he and the other crew members are ready for the challenge.

  20. The International Atomic Energy Agency’s Decision to Find Iran in Non-Compliance, 2002-2006

    Science.gov (United States)

    2012-12-01

    Organization of Iran ( AEOI ), made the first statement to address the country’s nuclear activities since the NCRI’s press conference: “Iran is embarking on a...Find Iran in Non-Compliance, 2002–2006 ElBaradei received a letter from AEOI chief Aghazadeh declaring that Iran was “commencing a new phase of...initiative of the A.Q. Khan network and not at the request of the AEOI . Despite the bad omen, the IAEA Board decided against a referral of Iran to

  1. Slovensky plynarensky priemysel. Annual report 2006

    International Nuclear Information System (INIS)

    2007-01-01

    This Annual Report contains the review of the results of the joint stock company Slovensky plynarensky priemysel (SPP - Slovak Gas Industry) and subsidiary corporations in relation to the year 2006. This report contains the following headings: I. SPP a. s.: (1) Statement by the Chairman of the Board of Directors; (2) Statement by the General Director; (3) SPP a. s. Board of Directors as at 31. 12. 2006; (3) SPP a. s. Top Executive Management as at 31. 12. 2006; (4) SPP a. s. Supervisory Board as at 31. 12. 2006; (5) SPP a. s. - Company Profile; (6) Organisational Structure of SPP a. s. applicable as of 31. 12. 2006; (7) Economic and Financial Performance; (8) Capital Structure; (9) Natural Gas Trade; (10) Equity Holdings; (11) Summary results of SPP a. s. and Independent Auditor's Report; (12) SPP a. s. - Contact. II. SPP - distribucia a. s.: (1)Statement by the Chairman of the Board of Directors of SPP - distribucia a. s.; (2) Statement by the General Director of SPP - distribucia a. s.; (3) Establishment of the company SPP - distribucia a. s.; (4) SPP - distribucia a. s. Board of Directors as at 31. 12. 2006; (5) SPP - distribucia a. s. Supervisory Board as at 31. 12. 2006; (6) Organisational structure of SPP- distribucia a. s. applicable as of 31. 12. 2006; (7) Natural Gas Distribution; (8) SPP - distribucia a. s. - Contact. III. SPP - preprava a. s.: (1) Statement by the Chairman of the Board of Directors of SPP - preprava a. s.; (2) Statement by the General Director of SPP - preprava a. s.; (3) Establishment of the company SPP - preprava a. s.; (4) SPP - preprava a. s. Board of Directors as at 31. 12. 2006; (5) SPP - preprava a. s. Supervisory Board as at 31. 12. 2006; (6) Organisational structure of SPP - preprava a. s applicable as of 31. 12. 2006; (7) Natural Gas Transmission; (8) SPP - preprava a. s. - Contact. IV. SPP Core Group: (1) Vision, Mission; (2) Code of Conduct and the Company's Core Values; (3) Human Resources; (4) Safety and Environmental

  2. Slovensky plynarensky priemysel. Annual report 2006

    International Nuclear Information System (INIS)

    2007-01-01

    This Annual Report contains the review of the results of the joint stock company Slovensky plynarensky priemysel (SPP - Slovak Gas Industry) and subsidiary corporations in relation to the year 2006. This report contains the following headings: I. SPP a. s.: (1) Statement by the Chairman of the Board of Directors; (2) Statement by the General Director; (3) SPP a. s. Board of Directors as at 31. 12. 2006; (3) SPP a. s. Top Executive Management as at 31. 12. 2006; (4) SPP a. s. Supervisory Board as at 31. 12. 2006; (5) SPP a. s. - Company Profile; (6) Organisational Structure of SPP a. s. applicable as of 31. 12. 2006; (7) Economic and Financial Performance; (8) Capital Structure; (9) Natural Gas Trade; (10) Equity Holdings; (11) Summary results of SPP a. s. and Independent Auditor's Report; (12) SPP a. s. - Contact. II. SPP - distribucia a. s.: (1) Statement by the Chairman of the Board of Directors of SPP - distribucia a. s.; (2) Statement by the General Director of SPP - distribucia a. s.; (3) Establishment of the company SPP - distribucia a. s.; (4) SPP - distribucia a. s. Board of Directors as at 31. 12. 2006; (5) SPP - distribucia a. s. Supervisory Board as at 31. 12. 2006; (6) Organisational structure of SPP- distribucia a. s. applicable as of 31. 12. 2006; (7) Natural Gas Distribution; (8) SPP - distribucia a. s. - Contact. III. SPP - preprava a. s.: (1) Statement by the Chairman of the Board of Directors of SPP - preprava a. s.; (2) Statement by the General Director of SPP - preprava a. s.; (3) Establishment of the company SPP - preprava a. s.; (4) SPP - preprava a. s. Board of Directors as at 31. 12. 2006; (5) SPP - preprava a. s. Supervisory Board as at 31. 12. 2006; (6) Organisational structure of SPP - preprava a. s applicable as of 31. 12. 2006; (7) Natural Gas Transmission; (8) SPP - preprava a. s. - Contact. IV. SPP Core Group: (1) Vision, Mission; (2) Code of Conduct and the Company's Core Values; (3) Human Resources; (4) Safety and Environmental

  3. 14 CFR 1221.112 - Use of the NASA Program Identifiers.

    Science.gov (United States)

    2010-01-01

    ..., NASA Program Identifiers, NASA Flags, and the Agency's Unified Visual Communications System § 1221.112... for Public Affairs. (e) The manufacture, sale, or use of any colorable imitation of the design of an...

  4. MicroRNA Dysregulation, Gene Networks, and Risk for Schizophrenia in 22q11.2 Deletion Syndrome

    OpenAIRE

    Merico, Daniele; Costain, Gregory; Butcher, Nancy J.; Warnica, William; Ogura, Lucas; Alfred, Simon E.; Brzustowicz, Linda M.; Bassett, Anne S.

    2014-01-01

    The role of microRNAs (miRNAs) in the etiology of schizophrenia is increasingly recognized. Microdeletions at chromosome 22q11.2 are recurrent structural variants that impart a high risk for schizophrenia and are found in up to 1% of all patients with schizophrenia. The 22q11.2 deletion region overlaps gene DGCR8, encoding a subunit of the miRNA microprocessor complex. We identified miRNAs overlapped by the 22q11.2 microdeletion and for the first time investigated their predicted target genes...

  5. EDF - Electricite de France, 2006 annual Results

    International Nuclear Information System (INIS)

    2007-01-01

    The EDF Group is an integrated energy supplier operating in a wide range of electricity-related businesses: generation, transmission, distribution, sale and trading of energy. It is the main operator in the French electricity market and one of the leading electricity groups in Europe. The EDF Group has built a business model balanced between deregulated and regulated operations in France and an international presence. This document is EDF Group's annual Results for 2006. It is made of several reports: the 2006 Annual Results presentation, the 2006 Financial Report, the press releases for the first and third quarters 2006 quarterly financial information, the 2006 Half-year results presentation, the Management Report for the first half 2006, and the consolidated financial statements at 30 June 2006

  6. CERN Technical Training 2006: ANSYS Course Sessions (August-September 2006)

    CERN Multimedia

    Davide Vitè

    2006-01-01

    If you wish to participate in one of the following courses, please tell to your supervisor and apply electronically from the course description pages that can be found on the Web at: http://www.cern.ch/Training/ or fill in an 'application for training'form available from your Departmental Secretariat or from your DTO (Departmental Training Officer). Applications will be accepted in the order in which they are received. The following ANSYS course sessions are currently scheduled in the framework of the CERN Technical Training Programme 2006, and in collaboration with CAD-FEM AG (CH): ANSYS DesignModeler (course in French): 29-30.8.2006 (2 days) ANSYS Workbench (course in French): 12-15.9.2006 (4 days, only 3 places available) If you are interested in attending any of the above course sessions, please discuss with your supervisor and/or your DTO, and apply electronically via EDH from the course description pages that can be found at http://cta.cern.ch/cta2/f?p=300 under 'Upcoming course sessions', with th...

  7. Facilitators and constraints at each stage of the migration decision process.

    Science.gov (United States)

    Kley, Stefanie

    2017-10-01

    Behavioural models of migration emphasize the importance of migration decision-making for the explanation of subsequent behaviour. But empirical migration research regularly finds considerable gaps between those who intend to migrate and those who actually realize their intention. This paper applies the Theory of Planned Behaviour, enriched by the Rubicon model, to test specific hypotheses about distinct effects of facilitators and constraints on specific stages of migration decision-making and behaviour. The data come from a tailor-made panel survey based on random samples of people drawn from two German cities in 2006-07. The results show that in conventional models the effects of facilitators and constraints on migration decision-making are likely to be underestimated. Splitting the process of migration decision-making into a pre-decisional and a pre-actional phase helps to avoid bias in the estimated effects of facilitators and constraints on both migration decision-making and migration behaviour.

  8. End-of-year-closure 2005/2006

    CERN Multimedia

    HR Department

    2005-01-01

    As announced in Weekly Bulletin Nº 2/2005, the Laboratory will be closed from Thursday 22 December 2005 to Wednesday 4 January 2006 inclusive. This period consists of 14 days: 4 days' official holiday, i.e. 24, 25 and 31 December 2005 and 1st January 2006; 6 days' special paid leave in accordance with Article R II 4.34 of the Staff Regulations, i.e.  26, 27, 28, 29, 30 December 2005 and 4 January 2006; 4 days, 22 and 23 December 2005 to compensate for 24 and 25 December 2005 and 2 and 3 January 2006 to compensate for 31 December 2005 and 1st January 2006 (Article R II 4.33 of the Staff Regulations); The first working day in the New Year will be Thursday, 5 January 2006. Further information is available from Department Secretariats, specifically concerning the conditions applicable to members of the personnel who are required to work during this period. Human Resources Department Tel. 73903

  9. End-of-year-closure 2005/2006

    CERN Multimedia

    2005-01-01

    As announced in Weekly Bulletin No. 2/2005, the Laboratory will be closed from Thursday 22 December 2005 to Wednesday 4 January 2006 inclusive. This period consists of 14 days: 4 days' official holiday, i.e. 24, 25 and 31 December 2005 and 1st January 2006; 6 days' special paid leave in accordance with Article R II 4.34 of the Staff Regulations, i.e.  26, 27, 28, 29, 30 December 2005 and 4 January 2006; 4 days, 22 and 23 December 2005 to compensate for 24 and 25 December 2005 and 2 and 3 January 2006 to compensate for 31 December 2005 and 1st January 2006 (Article R II 4.33 of the Staff Regulations); The first working day in the New Year will be Thursday, 5 January 2006. Further information is available from Department Secretariats, specifically concerning the conditions applicable to members of the personnel who are required to work during this period. Human Resources Department Tel. 73903

  10. LPGs in 2006

    International Nuclear Information System (INIS)

    Anon.

    2007-01-01

    During the 2006 year, the French committee of butane and propane (CFBP) went on with mobilizing and sustaining the LPG industry companies in their actions for improving and valorizing the energy efficiency of butane, propane, and LPG fuels. These efforts were carried out in a context of general decay of energy consumption in France and in particular for LPG. The publication of the 2006 activity report of CFBP is a good opportunity to make a status of the development of this industry. (J.S.)

  11. The european emergency number 112 - the questionnaire

    OpenAIRE

    Goniewicz Krzysztof; Goniewicz Mariusz; Misztal Okońska Patrycja; Witold Pawłowski; Czerski Robert

    2017-01-01

    Goniewicz Krzysztof, Goniewicz Mariusz, Misztal Okońska Patrycja, Witold Pawłowski, Czerski Robert. The european emergency number 112 - the questionnaire. Journal of Education, Health and Sport. 2017;7(7):1165-1174. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1117736 http://ojs.ukw.edu.pl/index.php/johs/article/view/5134 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01....

  12. MAKE UP SEPT 2006

    African Journals Online (AJOL)

    Winnie

    2006-09-01

    Sep 1, 2006 ... had led to an interest in the concept of STIs – providing breaks in therapy in a structured fashion to minimise the ... was terminated by the Data Safety Monitoring Board in. January 2006 because of an increased risk ... This study assessed the safety of a single treatment interruption in a cohort of patients who ...

  13. 2006 statistical data of the French gas industry; Statistiques 2006 de l'industrie gaziere en France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-12-15

    This document makes a synthesis of the 2006 results of the annual inquiry about the French natural gas industry: 1 - organization of the French gas market (production, transport, methane terminals, storage facilities, distribution, commercialization, main steps of the opening of the gas market in France); 2 - the 2006 gas year (consumption, imports, production, stockpiles); 3 - results of the 2006 inquiry: infrastructures (storage capacities, pipelines and distribution network), production (evolution of natural gas and industrial gases production, uses), transport (inputs and outputs, geographical origin of inputs in 2005 and 2006, raw imports evolution since 1973), storage (evolution of stockpiles variation), natural gas supplies (sectoral uses), supplies by region and by sector in 2006, consumption by sector; 4 - power generation by gas cogeneration in 2005 (plants characteristics, classification, cogeneration status (in TWh), regional distribution of plants); 5 - 2006 monthly changes (inputs, net imports, consumption and useful stockpile, consumption and net imports); 6 - international comparisons (gas share in the overall energy consumption, consumption per user, evolution of main sectors of consumption in some European countries since 1973); 7 - appendixes: French transportation network, main gas roads in Europe, European gas fluxes, 2006 energy status, gas statuses during the past three years. (J.S.)

  14. A Study of the Relationship between Family Communication Patterns and Adolescents’ Pre-Purchase Decision-Making Process

    OpenAIRE

    Shahriar Azizi; Abasali Haji Karimi; Saedeh Haji Ebrahimi; Amin Dini

    2013-01-01

    Introduction Today's adolescents have a great influence on the family purchasing behavior. Adolescent's critical role is based on the four pillars: 1) they have more money for purchasing, 2) they are potential consumers in the future, 3) adolescents influence family purchasing decisions (Hawkins, 2006), and 4) they receive more attention from their parents. According to the last statistics of IRAN general census in 2006, adolescents (aged 15-19) composed %38.12 .of the total population. So...

  15. Mitmekülgne eesti lastekirjandus [2006. a.] / Jaanika Palm

    Index Scriptorium Estoniae

    Palm, Jaanika, 1973-

    2008-01-01

    Arvustus: Tungal, Leelo. Lätikeelne jäätis ja teisi luuletusi. Tallinn : Tuum, 2006 ; Trull, Ilmar. Musta kassi mumba. Tallinn : Eesti Ekspressi Kirjastus, 2006 ; Wimberg. Põngerjate laulud. Tallinn : Varrak, 2006 ; Muidugi, Eino. Lõbus pere ütleb tere! Tallinn : Koolibri, 2006 ; Nemvalts, Urmas. Väikeste meeste jutud. [Tallinn] : Grenader, 2006 ; Kangro, Maarja, Kangro, Kirke. Puuviljadraakon. Tallinn : Koolibri, 2006 ; Kilkson, Tiina. Pisikese Peetri pikk pühapäev. Tallinn : Koolibri, 2006 ; Pelmas, Elsa. Sussipäkapikk Siisi seiklused. Tallinn : TEA Kirjastus, 2006 ; Sauter, Peeter. Laiskade laste raamat. Tallinn : Huma, 2006 ; Kivirähk, Andrus. Leiutajateküla Lotte. Tallinn : Eesti Joonisfilm, 2006 ; Ulman, Mihkel. Nukkude teater. Tartu : Elmatar, 2006 ; Rannap, Jaan. Roheline kindlus. Tallinn : Tiritamm, 2006 ; Vallik, Aidi. Narkohollo ehk Florose vabastamine. Haapsalu : Lugu-Loo, 2006 ; Leesalu, Diana. Mängult on päriselt. Tallinn : Tänapäev, 2006 ; Laidla, Siiri. Pärnaõietee. Tallinn : Canopus, 2006

  16. Mitmekülgne eesti lastekirjandus [2006. a.] / Jaanika Palm

    Index Scriptorium Estoniae

    Palm, Jaanika, 1973-

    2007-01-01

    Arvustus: Tungal, Leelo. Lätikeelne jäätis ja teisi luuletusi. Tallinn : Tuum, 2006 ; Trull, Ilmar. Musta kassi mumba. Tallinn : Eesti Ekspressi Kirjastus, 2006 ; Wimberg. Põngerjate laulud. Tallinn : Varrak, 2006 ; Muidugi, Eino. Lõbus pere ütleb tere! Tallinn : Koolibri, 2006 ; Nemvalts, Urmas. Väikeste meeste jutud. [Tallinn] : Grenader, 2006 ; Kangro, Maarja, Kangro, Kirke. Puuviljadraakon. Tallinn : Koolibri, 2006 ; Kilkson, Tiina. Pisikese Peetri pikk pühapäev. Tallinn : Koolibri, 2006 ; Pelmas, Elsa. Sussipäkapikk Siisi seiklused. Tallinn : TEA Kirjastus, 2006 ; Sauter, Peeter. Laiskade laste raamat. Tallinn : Huma, 2006 ; Kivirähk, Andrus. Leiutajateküla Lotte. Tallinn : Eesti Joonisfilm, 2006 ; Ulman, Mihkel. Nukkude teater. Tartu : Elmatar, 2006 ; Rannap, Jaan. Roheline kindlus. Tallinn : Tiritamm, 2006 ; Vallik, Aidi. Narkohollo ehk Florose vabastamine. Haapsalu : Lugu-Loo, 2006 ; Leesalu, Diana. Mängult on päriselt. Tallinn : Tänapäev, 2006 ; Laidla, Siiri. Pärnaõietee. Tallinn : Canopus, 2006

  17. 40 CFR 280.112 - Drawing on financial assurance mechanisms.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Drawing on financial assurance... OF UNDERGROUND STORAGE TANKS (UST) Financial Responsibility § 280.112 Drawing on financial assurance... agency may draw on a standby trust fund when: (1) The Director makes a final determination that a release...

  18. STS-112 Flight Day 7 Highlights

    Science.gov (United States)

    2002-10-01

    On this seventh day of STS-112 mission members of the crew (Commander Jeff Ashby; Pilot Pam Melroy; Mission Specialist Sandy Magnus, Piers Sellers, Dave Wolf, and Fyodor Yurchikhin) along with the Expedition Five crew (Commander Valery Korzun; Flight Engineer Peggy Whitson, and Sergei Treschev) are seen answering questions during the mission's press interview and photo opportunity. They answered various questions regarding the mission's objectives, the onboard science experiments, the extravehicular activities (EVAs) and the effects of living in space. Shots of the test deployment of the S1 truss radiator and Canadarm rotor joint are also shown.

  19. Advance directives and outcomes of surrogate decision making before death.

    Science.gov (United States)

    Silveira, Maria J; Kim, Scott Y H; Langa, Kenneth M

    2010-04-01

    Recent discussions about health care reform have raised questions regarding the value of advance directives. We used data from survey proxies in the Health and Retirement Study involving adults 60 years of age or older who had died between 2000 and 2006 to determine the prevalence of the need for decision making and lost decision-making capacity and to test the association between preferences documented in advance directives and outcomes of surrogate decision making. Of 3746 subjects, 42.5% required decision making, of whom 70.3% lacked decision-making capacity and 67.6% of those subjects, in turn, had advance directives. Subjects who had living wills were more likely to want limited care (92.7%) or comfort care (96.2%) than all care possible (1.9%); 83.2% of subjects who requested limited care and 97.1% of subjects who requested comfort care received care consistent with their preferences. Among the 10 subjects who requested all care possible, only 5 received it; however, subjects who requested all care possible were far more likely to receive aggressive care as compared with those who did not request it (adjusted odds ratio, 22.62; 95% confidence interval [CI], 4.45 to 115.00). Subjects with living wills were less likely to receive all care possible (adjusted odds ratio, 0.33; 95% CI, 0.19 to 0.56) than were subjects without living wills. Subjects who had assigned a durable power of attorney for health care were less likely to die in a hospital (adjusted odds ratio, 0.72; 95% CI, 0.55 to 0.93) or receive all care possible (adjusted odds ratio, 0.54; 95% CI, 0.34 to 0.86) than were subjects who had not assigned a durable power of attorney for health care. Between 2000 and 2006, many elderly Americans needed decision making near the end of life at a time when most lacked the capacity to make decisions. Patients who had prepared advance directives received care that was strongly associated with their preferences. These findings support the continued use of advance

  20. Social Impairments in Chromosome 22q11.2 Deletion Syndrome (22q11.2DS): Autism Spectrum Disorder or a Different Endophenotype?

    Science.gov (United States)

    Angkustsiri, Kathleen; Goodlin-Jones, Beth; Deprey, Lesley; Brahmbhatt, Khyati; Harris, Susan; Simon, Tony J.

    2014-01-01

    High prevalence of autism spectrum disorders (ASD) has been reported in 22q11.2DS, although this has been based solely on parent report measures. This study describes the presence of ASD using a procedure more similar to that used in clinical practice by incorporating history (Social Communication Questionnaire) AND a standardized observation…

  1. Reduction in acute myocardial infarction mortality in the United States: risk-standardized mortality rates from 1995-2006.

    Science.gov (United States)

    Krumholz, Harlan M; Wang, Yun; Chen, Jersey; Drye, Elizabeth E; Spertus, John A; Ross, Joseph S; Curtis, Jeptha P; Nallamothu, Brahmajee K; Lichtman, Judith H; Havranek, Edward P; Masoudi, Frederick A; Radford, Martha J; Han, Lein F; Rapp, Michael T; Straube, Barry M; Normand, Sharon-Lise T

    2009-08-19

    During the last 2 decades, health care professional, consumer, and payer organizations have sought to improve outcomes for patients hospitalized with acute myocardial infarction (AMI). However, little has been reported about improvements in hospital short-term mortality rates or reductions in between-hospital variation in short-term mortality rates. To estimate hospital-level 30-day risk-standardized mortality rates (RSMRs) for patients discharged with AMI. Observational study using administrative data and a validated risk model to evaluate 3,195,672 discharges in 2,755,370 patients discharged from nonfederal acute care hospitals in the United States between January 1, 1995, and December 31, 2006. Patients were 65 years or older (mean, 78 years) and had at least a 12-month history of fee-for-service enrollment prior to the index hospitalization. Patients discharged alive within 1 day of an admission not against medical advice were excluded, because it is unlikely that these patients had sustained an AMI. Hospital-specific 30-day all-cause RSMR. At the patient level, the odds of dying within 30 days of admission if treated at a hospital 1 SD above the national average relative to that if treated at a hospital 1 SD below the national average were 1.63 (95% CI, 1.60-1.65) in 1995 and 1.56 (95% CI, 1.53-1.60) in 2006. In terms of hospital-specific RSMRs, a decrease from 18.8% in 1995 to 15.8% in 2006 was observed (odds ratio, 0.76; 95% CI, 0.75-0.77). A reduction in between-hospital heterogeneity in the RSMRs was also observed: the coefficient of variation decreased from 11.2% in 1995 to 10.8%, the interquartile range from 2.8% to 2.1%, and the between-hospital variance from 4.4% to 2.9%. Between 1995 and 2006, the risk-standardized hospital mortality rate for Medicare patients discharged with AMI showed a significant decrease, as did between-hospital variation.

  2. Overweight and Underweight Prevalence Trends in Children from Romania - Pooled Analysis of Cross-Sectional Studies between 2006 and 2015.

    Science.gov (United States)

    Chirita-Emandi, Adela; Barbu, Carmen Gabriela; Cinteza, Elena Eliza; Chesaru, Bianca Ioana; Gafencu, Mihai; Mocanu, Veronica; Pascanu, Ionela M; Tatar, Simona Alexandra; Balgradean, Mihaela; Dobre, Michaela; Fica, Simona Vasilica; Ichim, Gabriela Edita; Pop, Raluca; Puiu, Maria

    2016-01-01

    High-quality national representative data on obesity in Romanian children are needed to shape public health policies. To provide a unified data landscape on national prevalence, trends and other factors associated with underweight, overweight, and obesity in Romanian children aged 6-19 years, across the last decade (2006-2015). Using a common protocol, we selected published and unpublished studies that measured Romanian children in schools between 2006 and 2015. Children's BMI was classified using the current WHO, IOTF, and CDC references. 25,060 children from 8 Romanian counties were included in the analysis. The prevalence of underweight children was 5%/4.5%/8.5% (WHO/IOTF/CDC), while the prevalence of overweight (including obese) children was 28.3%/23%/23.2% (WHO/IOTF/CDC). The prevalence of overweight children did not change significantly over the last decade (chi-square test p = 0.6). Male gender (odds ratio (OR) 1.37; 95% CI 1.29-1.45, compared to female); prepubertal age (OR = 3.86; 95% CI 3.41-4.36,compared to postpubertal age), and urban environment (OR 1.12; 95% CI 1.01-1.26, compared to rural environment) had higher risk for overweight. While the prevalence of underweight children was low, almost one in four children in Romania was overweight or obese (according to WHO criteria) between 2006 and 2015. This prevalence remained relatively stable over the last decade. Male gender, prepubertal age, and urban environment, were the most relevant risk factors associated with overweight status in Romanian children. © 2016 The Author(s) Published by S. Karger GmbH, Freiburg.

  3. Modelling the motion of {112-bar 2} twinning dislocations in the HCP metals

    International Nuclear Information System (INIS)

    Serra, A.; Bacon, D.J.

    2005-01-01

    Deformation twinning is important for plasticity of the hcp metals, but little is known about the dynamics of the mechanisms that control twin boundary motion. With the exception of the {112-bar 1} twin, atomic shuffles are required for glide of twinning dislocations and hence boundary movement is temperature-dependent. A computer method has been developed to simulate a step with dislocation character in a boundary with full periodicity in the boundary plane, i.e. along both the direction of the line of the defect and its direction of motion. It may be used to investigate the properties of such interfaces as the defects in them move over large distances. We explain the nature of the method and apply it to study the motion of twinning dislocations in the {112-bar 2} boundary as a function of applied stress and temperature. A new reaction at the boundary leading to the creation of a (c+a) crystal dislocation and a {112-bar 1} micro-twin is described

  4. Magnetic properties of deformed dipole bands in 110,112Te

    International Nuclear Information System (INIS)

    Evans, A O; Paul, E S; Boston, A J; Chantler, H J; Chiara, C J; Devlin, M; Fletcher, A M; Fossan, D B; LaFosse, D R; Lane, G J; Lee, I Y; Macchiavelli, A O; Nolan, P J; Sarantites, D G; Sears, J M; Semple, A T; Smith, J F; Starosta, K; Vaman, C; Ragnarsson, I; Afanasjev, A V

    2006-01-01

    A lifetime analysis using the Doppler-shift attenuation method has been performed on the Tellurium isotopes 110,112 Te. The experiment was performed using the Gammasphere array in conjunction with the MICROBALL charged-particle detector. Three strongly coupled bands were previously established in 110,112 Te which were observed up to unusually high spins. In the current experiment, it has been possible to extract lifetime measurements using a Doppler broadened lineshape analysis on one of the ΔI=1 band structures in 110 Te. In contrast to similar ΔI=1 structures in other nuclei in this mass region, the extracted B(M1) values did not rapidly decrease with increasing angular momentum. Instead, the strongly coupled band in 110 Te represents a deformed 1p-1h structure, rather than a weakly deformed structure showing the shears mechanism

  5. Public safety and sour gas quarterly progress report October - December 2002

    Energy Technology Data Exchange (ETDEWEB)

    Sikora, V.; Lillo, H.; Craig, M.; Neilson, G.

    2003-01-01

    This third quarterly progress report for the business year 2002-2003 on the Alberta Energy and Utilities Board (EUB) Public Safety and Sour Gas initiative covers projects based on the 87 recommendations made by the Provincial Advisory Committee on Public Safety and Sour Gas (Advisory Committee) in December 2000. As of December 2002, work has been completed on 16 recommendations and is proceeding on 50 recommendations. This report includes several tables indicating the status of recommendations as either complete or ongoing. The recommendation categories include: (1) sour gas development, planning and approval, (2) sour gas operations, (3) emergency preparedness, and (4) information, communication and consultation. The report also summarizes the health effects and sour gas research. Recommendations completed as of December 2002 include: plant proliferation; pre-license review of critical well license applications; license application training/certification information requirement; increase sour gas inspections; increase inspections of new and noncompliant operators; implement 100 per cent inspection rate for critical wells near people; response to sour gas complaints; enhance EUB capability to monitor for complaint response/compliance; complaint/incident response program for Aboriginal communities; interim policy on ERP review and reduced EPZs; infrastructure and resources for Aboriginal community ERP; field staff in industry-landowner discussions; EUB involvement in mediation of application issues; and, timely and meaningful public consultation for First Nations and Metis. Alberta Health and Wellness is currently evaluating the health effects of H{sub 2}S and SO{sub 2} and the work is near completion. Other ongoing work includes the development of a draft protocol to address the involvement of regional health authorities (RHAs), the early involvement of RHAs and other local government bodies, and a process for communication between the EUB field staff and

  6. Negative subthreshold psychotic symptoms distinguish 22q11.2 deletion syndrome from other neurodevelopmental disorders: A two-site study.

    Science.gov (United States)

    Mekori-Domachevsky, Ehud; Guri, Yael; Yi, James; Weisman, Omri; Calkins, Monica E; Tang, Sunny X; Gross, Raz; McDonald-McGinn, Donna M; Emanuel, Beverly S; Zackai, Elaine H; Zalsman, Gil; Weizman, Abraham; Gur, Ruben C; Gur, Raquel E; Gothelf, Doron

    2017-10-01

    About one third of individuals with 22q11.2 deletion syndrome (22q11.2DS) develop schizophrenia. Notably, a full-blown psychotic disorder is usually preceded by subthreshold symptoms. Therefore, it is important to identify early signs of psychosis in this population, a task that is complicated by the intellectual disabilities typically seen in 22q11.2DS. We aimed to identify subthreshold psychotic symptoms that distinguish 22q11.2DS from other neurodevelopmental disorders. The study included two independent cohorts from Tel Aviv and Philadelphia. 22q11.2DS (N=171) and typically developing (TD; N=832) individuals were enrolled at both sites and further compared to two groups with intellectual disabilities: Williams syndrome (WS; N=21) in the Tel Aviv cohort and idiopathic developmental disabilities (IDD; N=129) in the Philadelphia cohort. Participants and their primary caregivers were interviewed with the Structured Interview for Prodromal Symptoms (SIPS) and psychopathologies were assessed using standardized tools; general cognitive abilities were assessed with the Computerized Neurocognitive Battery. Negative/disorganized subthreshold syndrome was significantly more common in the 22q11.2DS group than in the WS (OR=3.90, 95% CI=1.34-11.34) or IDD (OR=5.05, 95% CI=3.01-10.08) groups. The 22q11.2DS group had higher scores than the two intellectual disabilities groups on several SIPS negative items, including avolition and decreased expression of emotion. Overall, there were few significant correlations between level of cognitive deficits and severity of negative symptoms in 22q11.2DS and only in the Tel Aviv cohort. Our findings suggest that 22q11.2DS individuals at the age of risk for developing psychosis should be closely monitored for negative symptoms. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. MRI-based decision tree model for diagnosis of biliary atresia.

    Science.gov (United States)

    Kim, Yong Hee; Kim, Myung-Joon; Shin, Hyun Joo; Yoon, Haesung; Han, Seok Joo; Koh, Hong; Roh, Yun Ho; Lee, Mi-Jung

    2018-02-23

    To evaluate MRI findings and to generate a decision tree model for diagnosis of biliary atresia (BA) in infants with jaundice. We retrospectively reviewed features of MRI and ultrasonography (US) performed in infants with jaundice between January 2009 and June 2016 under approval of the institutional review board, including the maximum diameter of periportal signal change on MRI (MR triangular cord thickness, MR-TCT) or US (US-TCT), visibility of common bile duct (CBD) and abnormality of gallbladder (GB). Hepatic subcapsular flow was reviewed on Doppler US. We performed conditional inference tree analysis using MRI findings to generate a decision tree model. A total of 208 infants were included, 112 in the BA group and 96 in the non-BA group. Mean age at the time of MRI was 58.7 ± 36.6 days. Visibility of CBD, abnormality of GB and MR-TCT were good discriminators for the diagnosis of BA and the MRI-based decision tree using these findings with MR-TCT cut-off 5.1 mm showed 97.3 % sensitivity, 94.8 % specificity and 96.2 % accuracy. MRI-based decision tree model reliably differentiates BA in infants with jaundice. MRI can be an objective imaging modality for the diagnosis of BA. • MRI-based decision tree model reliably differentiates biliary atresia in neonatal cholestasis. • Common bile duct, gallbladder and periportal signal changes are the discriminators. • MRI has comparable performance to ultrasonography for diagnosis of biliary atresia.

  8. Clarification of the interaction between Au atoms and the anatase TiO2 (112) surface using density functional theory

    Science.gov (United States)

    Tada, Kohei; Koga, Hiroaki; Okumura, Mitsutaka; Tanaka, Shingo

    2018-04-01

    A model (112) surface slab of anatase TiO2 (112) was optimized, and the adsorption of Au atoms onto the (112) surface was investigated by first-principles calculations based on DFT (density functional theory) with the generalized gradient approximation (GGA). Furthermore, the results were compared with those of Au/anatase TiO2 (101) system. The (112) surface has a ridge and a groove (zig-zag structure). The Au atoms were strongly adsorbed in the grooves but became unstable as they climbed toward the ridges, and the promotion of electrons in the 5d orbitals to the 6s and 6p orbitals in the absorbed Au atom occurred. At the Au/anatase TiO2 interface, the Au-Ti4+ coordinate bond in the (112) system is stronger than that in the (101) system because the promotion of electrons is greater in the former interaction than the latter. The results suggest that Au/anatase TiO2 catalysts with a higher dispersion of Au nanoparticles could be prepared when the (112) surface is preferentially exposed.

  9. The multislice CT findings of renal carcinoma associated with XP11.2 translocation/TFE gene fusion and collecting duct carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Qingqiang; Zhu Wenrong; Chen Wenxin; Wu Jingtao [Subei People' s Hospital, Clinical School of Medical Coll., Yangzhou (China)], e-mail: wujingtaodoctor@163.com; Wang Zhongqiu [Dept. of Radiology, East Hospital, Tongji Univ. School of Medicine, Shanghai (China)

    2013-04-15

    Background: Renal cell carcinoma associated with Xp11.2 translocation and TFE gene fusion (Xp11.2/TFE RCC), and collecting duct carcinoma (CDC) are uncommon subtypes of renal cell carcinomas. Purpose: To investigate the multislice CT (MSCT) characteristics of these two tumor types. Material and Methods Nine patients with Xp11.2/TFE RCC and 10 patients with CDC were studied retrospectively. MSCT was undertaken to investigate differences in tumor characteristics and enhancement patterns. Results: All patients had single tumors centered in the renal medulla. Two patients with each tumor type had lymph node involvement and there was a single case of hepatic metastasis (Xp11.2/TFE RCC). The mean tumor diameter of Xp11.2/TFE RCC tumors was significantly larger than for CDC tumors. Two patients with Xp11.2/TFE RCC had cystic components as did eight patients with CDC (P < 0.05). Calcifications were present in six patients, each with CDC. Clear tumor boundaries were visible in two patients with CDC and in nine with Xp11.2/TFE RCC (P < 0.05). The density of Xp11.2/TFE RCC tumors was greater than that of CDC tumors, normal renal cortex, or medulla on unenhanced CT. Enhancement was higher with Xp11.2/TFE RCC than with CDC tumors during all phases. Xp11.2/TFE RCC enhancement was higher than in the renal medulla during cortical and medullary phase but lower than in normal renal medulla during the delayed phase. CDC tumor enhancement was lower than that for normal renal medulla during all enhanced phases. Conclusion: Both tumor types originated from the renal medulla. Distinguishing features included density on unenhanced CT, enhancement patterns, and capsule signs. Identifying these differences may aid diagnosis.

  10. The clinical presentation of attention deficit‐hyperactivity disorder (ADHD) in children with 22q11.2 deletion syndrome

    Science.gov (United States)

    Martin, Joanna; Thapar, Anita; Owen, Michael J.

    2015-01-01

    Background: Although attention deficit‐hyperactivity disorder (ADHD) is the most prevalent psychiatric disorder in children with 22q11.2DS, it remains unclear whether its clinical presentation is similar to that in children with idiopathic ADHD. The aim of this study is to compare the ADHD phenotype in children with and without 22q11.2DS by examining ADHD symptom scores, patterns of psychiatric comorbidity, IQ and gender distribution. Methods: Forty‐four children with 22q11.2DS and ADHD (mean age = 9.6), 600 clinic children (mean age = 10.8) and 77 children with ADHD from a population cohort (mean age = 10.8) participated in the study. Psychopathology was assessed using parent‐report research diagnostic instruments. Results: There was a higher proportion of females in the 22q11.2DS ADHD sample in relation to the clinical sample (χ2 = 18.2, P ADHD inattentive subtype (χ2 = 114.76, P ADHD group parents reported fewer oppositional defiant disorder/conduct disorder symptoms (z = 6.33, P ADHD sample had received ADHD treatment. The results were similar when the 22q11.2 ADHD group was compared to the population cohort ADHD group. Conclusions: The clinical presentation of ADHD and patterns of co‐morbidity in 22q11.2DS is different from that in idiopathic ADHD. This could lead to clinical under‐recognition of ADHD in this group. Examining psychopathology in 22q11.2DS can provide insights into the genetic origins of psychiatric problems with implications beyond the 22q11.2DS population. © 2015 The Authors. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics Published by Wiley Periodicals, Inc. PMID:26400629

  11. Court decisions on medical malpractice.

    Science.gov (United States)

    Knaak, Jan-Paul; Parzeller, Markus

    2014-11-01

    Recent studies on court cases dealing with medical malpractice are few and far between. This retrospective study, therefore, undertakes an analysis of medical malpractice lawsuits brought before regional courts in two judicial districts of the federal state of Hesse. Over a 5-year period (2006-2010), 232 court decisions on medical malpractice taken by the regional courts (Landgericht) of Kassel and Marburg were evaluated according to medical discipline, diagnosis, therapy, relevant level of care, charge of neglect of duty by the claimant party, outcome of the lawsuit, and further criteria. With certain overlaps, the disciplines most frequently confronted with claims of medical malpractice were accident surgery and orthopedics (30.2%; n = 70), dentistry (16.4%; n = 38), surgery (12.1%; n = 28), and gynecology and obstetrics (7.8%; n = 18), followed by the remaining medical disciplines (38.8%; n = 90). Malpractice allegations were brought against the practice-based sector in 35.8 % (n = 83) of cases, the hospital-based sector in 63.3% (n = 147) of cases, and other sectors in 0.9% (n = 2) of cases. The allegation grounds included false administration of treatment (67.2%; n = 156), false indication of treatment (37.1%; n = 86), false diagnosis (31.5%; n = 73), and/or organizational negligence (13.8%; n = 32). A breach of duty to inform was given as grounds for the claim in 38.8% (n = 90) of cases. A significant majority of 65.6% (n = 152) of cases ended in a court settlement. Of the cases, 18.9% (n = 44) were concluded by claim withdrawal, 11.2% (n = 26) by claim dismissal and 2.6% (n = 6) by criminal sentence. Of the cases, 1.7% (n = 4) were for purposes of securing evidence. Although there was no conclusive evidence of malpractice, two thirds of the cases ended in a court settlement. On the one hand, this outcome reduces the burden on the courts, but on the other, it can in the long term give

  12. 3. quarter 2006 sales revenue; Chiffres d'affaires du 3. trimestre 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-10-15

    This document presents the sales revenue of the 3. quarter 2006 for the Group AREVA. The sales revenues for the first nine months of 2006 are up by 8,1% to 7,556 millions euros; the nuclear operations are up by 5,2% reflecting strong performance in the front end division; the transmission and distribution division is up by 14%. (A.L.B.)

  13. 19 CFR 11.2a - Release from Customs custody without payment of tax on cigars, cigarettes and cigarette papers...

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Release from Customs custody without payment of tax on cigars, cigarettes and cigarette papers and tubes. 11.2a Section 11.2a Customs Duties U.S... STAMPING; MARKING Packing and Stamping § 11.2a Release from Customs custody without payment of tax on...

  14. 14 CFR 1214.112 - Patent, data and information matters.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Patent, data and information matters. 1214... Customers § 1214.112 Patent, data and information matters. (a) Patent and data rights. NASA will not acquire rights to inventions, patents or proprietary data which may be used in, or arise from, activities for...

  15. Interfacing with the regulator after the year 2000

    International Nuclear Information System (INIS)

    Finlaison, J.G.; Karmali, A.

    1998-01-01

    Y2K experiences at the Alberta Energy and Utilities Board (EUB) and the Alberta Department of Energy (DOE) were highlighted. Work on Y2K problems at the DOE has been underway since 1995. The main focus has been on business applications, hardware and software. Currently the focus is on contingency planning. DOE's expectations are that industry will continue to submit data without any interruptions. Work on Y2K problems at the EUB was initiated in 1996, also focusing on business applications, hardware and software. Software has been upgraded where required. Building security and phone systems have been tested for compliance, and preparation of a contingency plan is underway. 1 fig

  16. 2006-2009年辽宁省大连市学龄儿童智商监测分析%Analysis of intelligence quotient of school children surveyed in Dalian city of Liaoning province during 2006 to 2009

    Institute of Scientific and Technical Information of China (English)

    姚伟; 张斌; 邵世亮; 梅丹; 陈凤义

    2011-01-01

    目的 了解实施全民食盐加碘后学龄儿童智商变化情况,为碘缺乏病防治工作提供科学依据.方法 2006-2009年选择辽宁省大连市11所小学校1580名儿童,采用中国联合型瑞文测验第二次修订版(CRT-C2)测验智商.智商分度及标准:非常优秀(≥130)、优秀(120~129)、中上(110~119)、中等(90~109)、中下(80~89)、边缘(70~79)、智力落后(≤69).采集儿童随意1次尿样(2006年未开展尿碘监测),用砷铈催化分光光度法检测尿碘.按监测年份及儿童出生年份分析全民食盐加碘前后儿童智商增长特点.结果 2006-2009年8~10岁儿童智商值分别为110.4 4-14.0、112.5±12.4、117.2 ±11.4、116.2±12.6,呈逐年增长趋势:2007-2009年与2006年比较年均增长值分别为2.1、3.4、1.9个智商点.2007-2009年8~10岁儿童尿碘中位数分别为224.7、266.7、222.1μg/L,均在200~300μg/L,人群碘营养处于超足量水平.1994-2000年出生的儿童智商值分别为106.7±13.0、108.1 ±13.9、108.5±134、111.3±14.3、113.6±12.5、115.3±12.3、119.8±11.2;1995-2000年与1994年比较年均增长值分别为1.4、0.9、1.5、1.7、1.7、2.2个智商点;智力落后和边缘智力的比例各年度均<2%;优秀和非常优秀的检出率呈逐年上升趋势,中等和中下的检出率呈逐年下降趋势(x2值分别为52.471、34.329、66.483、11.148,P均<0.01).结论 全民食盐加碘可快速提高学龄儿童智商水平.在碘缺乏病防治工作中,应加强智商指标的监测和应用.%Objective To obtain scientific data for control of iodine deficiency disorders(IDD) by reviewing the surveillance information of school children intelligence quotient(IQ) after the implementation of universal salt iodization. Methods One thousand five hundred and eighty children were selected from 11 primary school in Dalian city of Liaoning province during 2006 to 2009. IQ was measured by Combined Raven Test-C2(CRT-C2) in China. Groups of IQ

  17. Enhanced Maternal Origin of the 22q11.2 Deletion in Velocardiofacial and DiGeorge Syndromes

    DEFF Research Database (Denmark)

    Delio, Maria; Guo, Tingwei; McDonald-McGinn, Donna M

    2013-01-01

    Velocardiofacial and DiGeorge syndromes, also known as 22q11.2 deletion syndrome (22q11DS), are congenital-anomaly disorders caused by a de novo hemizygous 22q11.2 deletion mediated by meiotic nonallelic homologous recombination events between low-copy repeats, also known as segmental duplication...

  18. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion

    Directory of Open Access Journals (Sweden)

    Marcília S. Grassi

    2014-11-01

    Full Text Available Background: To alert for the diagnosis of the 22q11.2 deletion syndrome (22q11.2DS in patients with congenital heart disease (CHD. Objective: To describe the main CHDs, as well as phenotypic, metabolic and immunological findings in a series of 60 patients diagnosed with 22q11.2DS. Methods: The study included 60 patients with 22q11.2DS evaluated between 2007 and 2013 (M:F=1.3, age range 14 days to 20 years and 3 months at a pediatric reference center for primary immunodeficiencies. The diagnosis was established by detection of the 22q11.2 microdeletion using FISH (n = 18 and/or MLPA (n = 42, in association with clinical and laboratory information. Associated CHDs, progression of phenotypic facial features, hypocalcemia and immunological changes were analyzed. Results: CHDs were detected in 77% of the patients and the most frequent type was tetralogy of Fallot (38.3%. Surgical correction of CHD was performed in 34 patients. Craniofacial dysmorphisms were detected in 41 patients: elongated face (60% and/or elongated nose (53.3%, narrow palpebral fissure (50%, dysplastic, overfolded ears (48.3%, thin lips (41.6%, elongated fingers (38.3% and short stature (36.6%. Hypocalcemia was detected in 64.2% and decreased parathyroid hormone (PTH level in 25.9%. Decrease in total lymphocytes, CD4 and CD8 counts were present in 40%, 53.3% and 33.3%, respectively. Hypogammaglobulinemia was detected in one patient and decreased concentrations of immunoglobulin M (IgM in two other patients. Conclusion: Suspicion for 22q11.2DS should be raised in all patients with CHD associated with hypocalcemia and/or facial dysmorphisms, considering that many of these changes may evolve with age. The 22q11.2 microdeletion should be confirmed by molecular testing in all patients.

  19. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion

    International Nuclear Information System (INIS)

    Grassi, Marcília S.; Jacob, Cristina M. A.; Kulikowski, Leslie D.; Pastorino, Antonio C.; Dutra, Roberta L.; Miura, Nana; Jatene, Marcelo B.; Pegler, Stephanie P.; Kim, Chong A.; Carneiro-Sampaio, Magda

    2014-01-01

    To alert for the diagnosis of the 22q11.2 deletion syndrome (22q11.2DS) in patients with congenital heart disease (CHD). To describe the main CHDs, as well as phenotypic, metabolic and immunological findings in a series of 60 patients diagnosed with 22q11.2DS. The study included 60 patients with 22q11.2DS evaluated between 2007 and 2013 (M:F=1.3, age range 14 days to 20 years and 3 months) at a pediatric reference center for primary immunodeficiencies. The diagnosis was established by detection of the 22q11.2 microdeletion using FISH (n = 18) and/or MLPA (n = 42), in association with clinical and laboratory information. Associated CHDs, progression of phenotypic facial features, hypocalcemia and immunological changes were analyzed. CHDs were detected in 77% of the patients and the most frequent type was tetralogy of Fallot (38.3%). Surgical correction of CHD was performed in 34 patients. Craniofacial dysmorphisms were detected in 41 patients: elongated face (60%) and/or elongated nose (53.3%), narrow palpebral fissure (50%), dysplastic, overfolded ears (48.3%), thin lips (41.6%), elongated fingers (38.3%) and short stature (36.6%). Hypocalcemia was detected in 64.2% and decreased parathyroid hormone (PTH) level in 25.9%. Decrease in total lymphocytes, CD4 and CD8 counts were present in 40%, 53.3% and 33.3%, respectively. Hypogammaglobulinemia was detected in one patient and decreased concentrations of immunoglobulin M (IgM) in two other patients. Suspicion for 22q11.2DS should be raised in all patients with CHD associated with hypocalcemia and/or facial dysmorphisms, considering that many of these changes may evolve with age. The 22q11.2 microdeletion should be confirmed by molecular testing in all patients

  20. Congenital Heart Disease as a Warning Sign for the Diagnosis of the 22q11.2 Deletion

    Energy Technology Data Exchange (ETDEWEB)

    Grassi, Marcília S., E-mail: marcilia.grassi@hc.fm.usp.br; Jacob, Cristina M. A. [Instituto da Criança - HC-FMUSP, São Paulo, SP (Brazil); Kulikowski, Leslie D. [Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP (Brazil); Pastorino, Antonio C. [Instituto da Criança - HC-FMUSP, São Paulo, SP (Brazil); Dutra, Roberta L. [Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP (Brazil); Miura, Nana; Jatene, Marcelo B. [Instituto do Coração - HC-FMUSP, São Paulo, SP (Brazil); Pegler, Stephanie P.; Kim, Chong A.; Carneiro-Sampaio, Magda [Instituto da Criança - HC-FMUSP, São Paulo, SP (Brazil)

    2014-11-15

    To alert for the diagnosis of the 22q11.2 deletion syndrome (22q11.2DS) in patients with congenital heart disease (CHD). To describe the main CHDs, as well as phenotypic, metabolic and immunological findings in a series of 60 patients diagnosed with 22q11.2DS. The study included 60 patients with 22q11.2DS evaluated between 2007 and 2013 (M:F=1.3, age range 14 days to 20 years and 3 months) at a pediatric reference center for primary immunodeficiencies. The diagnosis was established by detection of the 22q11.2 microdeletion using FISH (n = 18) and/or MLPA (n = 42), in association with clinical and laboratory information. Associated CHDs, progression of phenotypic facial features, hypocalcemia and immunological changes were analyzed. CHDs were detected in 77% of the patients and the most frequent type was tetralogy of Fallot (38.3%). Surgical correction of CHD was performed in 34 patients. Craniofacial dysmorphisms were detected in 41 patients: elongated face (60%) and/or elongated nose (53.3%), narrow palpebral fissure (50%), dysplastic, overfolded ears (48.3%), thin lips (41.6%), elongated fingers (38.3%) and short stature (36.6%). Hypocalcemia was detected in 64.2% and decreased parathyroid hormone (PTH) level in 25.9%. Decrease in total lymphocytes, CD4 and CD8 counts were present in 40%, 53.3% and 33.3%, respectively. Hypogammaglobulinemia was detected in one patient and decreased concentrations of immunoglobulin M (IgM) in two other patients. Suspicion for 22q11.2DS should be raised in all patients with CHD associated with hypocalcemia and/or facial dysmorphisms, considering that many of these changes may evolve with age. The 22q11.2 microdeletion should be confirmed by molecular testing in all patients.

  1. Rare Genome-Wide Copy Number Variation and Expression of Schizophrenia in 22q11.2 Deletion Syndrome.

    Science.gov (United States)

    Bassett, Anne S; Lowther, Chelsea; Merico, Daniele; Costain, Gregory; Chow, Eva W C; van Amelsvoort, Therese; McDonald-McGinn, Donna; Gur, Raquel E; Swillen, Ann; Van den Bree, Marianne; Murphy, Kieran; Gothelf, Doron; Bearden, Carrie E; Eliez, Stephan; Kates, Wendy; Philip, Nicole; Sashi, Vandana; Campbell, Linda; Vorstman, Jacob; Cubells, Joseph; Repetto, Gabriela M; Simon, Tony; Boot, Erik; Heung, Tracy; Evers, Rens; Vingerhoets, Claudia; van Duin, Esther; Zackai, Elaine; Vergaelen, Elfi; Devriendt, Koen; Vermeesch, Joris R; Owen, Michael; Murphy, Clodagh; Michaelovosky, Elena; Kushan, Leila; Schneider, Maude; Fremont, Wanda; Busa, Tiffany; Hooper, Stephen; McCabe, Kathryn; Duijff, Sasja; Isaev, Karin; Pellecchia, Giovanna; Wei, John; Gazzellone, Matthew J; Scherer, Stephen W; Emanuel, Beverly S; Guo, Tingwei; Morrow, Bernice E; Marshall, Christian R

    2017-11-01

    Chromosome 22q11.2 deletion syndrome (22q11.2DS) is associated with a more than 20-fold increased risk for developing schizophrenia. The aim of this study was to identify additional genetic factors (i.e., "second hits") that may contribute to schizophrenia expression. Through an international consortium, the authors obtained DNA samples from 329 psychiatrically phenotyped subjects with 22q11.2DS. Using a high-resolution microarray platform and established methods to assess copy number variation (CNV), the authors compared the genome-wide burden of rare autosomal CNV, outside of the 22q11.2 deletion region, between two groups: a schizophrenia group and those with no psychotic disorder at age ≥25 years. The authors assessed whether genes overlapped by rare CNVs were overrepresented in functional pathways relevant to schizophrenia. Rare CNVs overlapping one or more protein-coding genes revealed significant between-group differences. For rare exonic duplications, six of 19 gene sets tested were enriched in the schizophrenia group; genes associated with abnormal nervous system phenotypes remained significant in a stepwise logistic regression model and showed significant interactions with 22q11.2 deletion region genes in a connectivity analysis. For rare exonic deletions, the schizophrenia group had, on average, more genes overlapped. The additional rare CNVs implicated known (e.g., GRM7, 15q13.3, 16p12.2) and novel schizophrenia risk genes and loci. The results suggest that additional rare CNVs overlapping genes outside of the 22q11.2 deletion region contribute to schizophrenia risk in 22q11.2DS, supporting a multigenic hypothesis for schizophrenia. The findings have implications for understanding expression of psychotic illness and herald the importance of whole-genome sequencing to appreciate the overall genomic architecture of schizophrenia.

  2. Annual Site Environmental Report: 2006

    International Nuclear Information System (INIS)

    Nuckolls, H

    2008-01-01

    This report provides information about environmental programs during the calendar year (CY) of 2006 at the Stanford Linear Accelerator Center (SLAC), Menlo Park, California. Activities that span the calendar year; i.e., stormwater monitoring covering the winter season of 2006/2007 (October 2006 through May 2007), are also included. Production of an annual site environmental report (ASER) is a requirement established by the United States Department of Energy (DOE) for all management and operating (M and O) contractors throughout the DOE complex. SLAC is a federally-funded research and development center with Stanford University as the M and O contractor. SLAC continued to follow the path to self-declare an environmental management system under DOE Order 450.1, 'Environmental Protection Program' and effectively applied environmental management in meeting the site's integrated safety and environmental management system goals. For normal daily activities, all SLAC managers and supervisors are responsible for ensuring that proper procedures are followed so that Worker safety and health are protected; The environment is protected; and Compliance is ensured. Throughout 2006, SLAC focused on these activities through the SLAC management systems. These systems were also the way SLAC approached implementing 'greening of the government' initiatives such as Executive Order 13148. The management systems at SLAC are effective, supporting compliance with all relevant statutory and regulatory requirements. The SLAC Office of Assurance was created during 2006 in response to DOE Order 226.1. During 2006, there were no reportable releases to the environment from SLAC operations, and there were no Notice of Violations issued to SLAC from any of the regulatory agencies that oversee SLAC. In addition, many improvements in waste minimization, recycling, stormwater drain system, groundwater restoration, and SLAC's chemical management system (CMS) were continued during 2006 to better manage

  3. Ethane-1,1,2-trisphosphonic acid hemihydrate.

    Science.gov (United States)

    Delain-Bioton, Lise; Lohier, Jean François; Villemin, Didier; Sopková-de Oliveira Santos, Jana; Hix, Gary; Jaffrès, Paul Alain

    2008-02-01

    Ethane-1,1,2-trisphosphonic acid crystallizes as a hemihydrate, C(2)H(9)O(9)P(3).0.5H(2)O, in which the water O atom lies on an inversion centre in the space group P2(1)/c. The acid component, which contains a short but noncentred O-H...O hydrogen bond, adopts a gauche conformation. The acid components are linked by an extensive series of O-H...O hydrogen bonds to form layers, which are linked into pairs by the water molecules.

  4. Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome

    DEFF Research Database (Denmark)

    Larsen, Kit Melissa; Mørup, Morten; Birknow, Michelle Rosgaard

    2018-01-01

    . Mismatch negativity (MMN), a brain marker of change detection, is reduced in people with schizophrenia compared to healthy controls. Using dynamic causal modelling (DCM), previous studies showed that top-down effective connectivity linking the frontal and temporal cortex is reduced in schizophrenia......11.2 deletion carriers. DCM showed reduced intrinsic connection within right primary auditory cortex as well as in the top-down, connection from the right inferior frontal gyrus to right superior temporal gyrus for 22q11.2 deletion carriers although not surviving correction for multiple comparison...

  5. Developmental course of conversational behaviour of children with 22q11.2 deletion syndrome and Williams syndrome

    OpenAIRE

    Van Den Heuvel, E.; Botting, N.; Boudewijns, I.; Manders, E.; Swillen, A.; Zink, I.

    2017-01-01

    This study investigated three conversational subskills in children with 22q11.2 deletion syndrome (22q11.2DS, n = 8, ages 7–13) and Williams syndrome (WS, n = 8, ages 6–12). We re-evaluated these subskills after 18 to 24 months and compared them to those of peers with idiopathic intellectual disability (IID) and IID and comorbid autism spectrum disorders (IID+ASD). Children with 22q11.2DS became less actively involved over time. Lower assertiveness than in children with IID was demonstrated. ...

  6. Energy situation, January 2006; Conjoncture energetique, janvier 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-15

    The monthly energy situation analysis in France, at January 2006, is presented. Statistics are given for energy consumption, demand, import and export. A special attention is given to the primary energy, the solid fuels, the petroleum products, the natural gas and the electric power. (A.L.B.)

  7. Vedelgaasi kasutamine Eestis 2006. aastal / Sandor Tabo

    Index Scriptorium Estoniae

    Tabo, Sandor

    2007-01-01

    Eesti vedelgaasiturg, müügikasv vedelgaasi kasutusviisi järgi. Diagramm: Vedelgaasi tarbimine Eestis 2001-2006. a. Tabel: Eesti vedelgaasiäriühingute peamised näitajad 2005-2006. a. Graafik: Vedelgaasi propaan hind maailmaturul 2002-2006. a.

  8. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2. 81...

  9. Does Differential Visual Exploration Contribute to Visual Memory Impairments in 22Q11.2 Microdeletion Syndrome?

    Science.gov (United States)

    Bostelmann, M.; Glaser, B.; Zaharia, A.; Eliez, S.; Schneider, M.

    2017-01-01

    Background: Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is a genetic syndrome characterised by a unique cognitive profile. Individuals with the syndrome present several non-verbal deficits, including visual memory impairments and atypical exploration of visual information. In this study, we seek to understand how visual attention may…

  10. POWERNEXT futures statistics November 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the November 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for November 2006, base-load and peak-load contracts overview from May 2005 or May 2006 to November 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price in euros/MWh), base-load and peak-load price spreads and market liquidity in November 2006 (average bid ask spread and availability). (J.S.)

  11. POWERNEXT futures statistics September 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the September 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for September 2006, base-load and peak-load contracts overview from April 2005 or March 2006 to September 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price in euros/MWh), base-load and peak-load price spreads and market liquidity in September 2006 (average bid ask spread and availability). (J.S.)

  12. Vitamin D deficiency, behavioral atypicality, anxiety and depression in children with chromosome 22q11.2 deletion syndrome.

    Science.gov (United States)

    Kelley, L; Sanders, A F P; Beaton, E A

    2016-12-01

    Chromosome 22q11.2 deletion syndrome (22q11.2DS) is a complex developmental disorder with serious medical, cognitive and emotional symptoms across the lifespan. This genetic deletion also imparts a lifetime risk for developing schizophrenia that is 25-30 times that of the general population. The origin of this risk is multifactorial and may include dysregulation of the stress response and immunological systems in relation to brain development. Vitamin D is involved in brain development and neuroprotection, gene transcription, immunological regulation and influences neuronal signal transduction. Low levels of vitamin D are associated with schizophrenia, depression and anxiety in the general population. Yet, little is known about how vitamin D levels in children with 22q11.2DS could mediate risk of psychosis in adulthood. Blood plasma levels of vitamin D were measured in children aged 7-16 years with (n=11) and without (n=16) 22q11.2DS in relation to parent reports of children's anxiety and atypicality. Anxiety and atypicality in childhood are risk indicators for the development of schizophrenia in those with 22q11.2DS and the general population. Children with 22q11.2DS had lower vitamin D levels, as well as elevated anxiety and atypicality compared with typical peers. Higher levels of anxiety, depression and internalizing problems but not atypicality were associated with lower levels of vitamin D. Vitamin D insufficiency may relate to higher levels of anxiety and depression, in turn contributing to the elevated risk of psychosis in this population. Further study is required to determine casual linkages between anxiety, stress, mood and vitamin D in children with 22q11.2DS.

  13. The hippocampi of children with chromosome 22q11.2 deletion syndrome have localized anterior alterations that predict severity of anxiety.

    Science.gov (United States)

    Scott, Julia A; Goodrich-Hunsaker, Naomi; Kalish, Kristopher; Lee, Aaron; Hunsaker, Michael R; Schumann, Cynthia M; Carmichael, Owen T; Simon, Tony J

    2016-04-01

    Individuals with 22q11.2 deletion syndrome (22q11.2DS) have an elevated risk for schizophrenia, which increases with history of childhood anxiety. Altered hippocampal morphology is a common neuroanatomical feature of 22q11.2DS and idiopathic schizophrenia. Relating hippocampal structure in children with 22q11.2DS to anxiety and impaired cognitive ability could lead to hippocampus-based characterization of psychosis-proneness in this at-risk population. We measured hippocampal volume using a semiautomated approach on MRIs collected from typically developing children and children with 22q11.2DS. We then analyzed hippocampal morphology with Localized Components Analysis. We tested the modulating roles of diagnostic group, hippocampal volume, sex and age on local hippocampal shape components. Lastly, volume and shape components were tested as covariates of IQ and anxiety. We included 48 typically developing children and 69 children with 22q11.2DS in our study. Hippocampal volume was reduced bilaterally in children with 22q11.2DS, and these children showed greater variation in the shape of the anterior hippocampus than typically developing children. Children with 22q11.2DS had greater inward deformation of the anterior hippocampus than typically developing children. Greater inward deformation of the anterior hippocampus was associated with greater severity of anxiety, specifically fear of physical injury, within the 22q11.2DS group. Shape alterations are not specific to hippocampal subfields. Alterations in the structure of the anterior hippocampus likely affect function and may impact limbic circuitry. We suggest these alterations potentially contribute to anxiety symptoms in individuals with 22q11.2DS through modulatory pathways. Altered hippocampal morphology may be uniquely linked to anxiety risk factors for schizophrenia, which could be a powerful neuroanatomical marker of schizophrenia risk and hence protection.

  14. A cross-sectional analysis of the development of response inhibition in children with Chromosome 22q11.2 Deletion Syndrome

    Directory of Open Access Journals (Sweden)

    Heather M Shapiro

    2013-08-01

    Full Text Available Chromosome 22q11.2 Deletion Syndrome (22q11.2DS is a neurogenetic disorder that is associated with cognitive impairments and significantly elevated risk for developing schizophrenia. While impairments in response inhibition are central to executive dysfunction in schizophrenia, the nature and development of such impairments in children with 22q11.2DS, a group at high risk for the disorder, are not clear. Here we used a classic Go/No-Go paradigm to quantify proactive (anticipatory stopping and reactive (actual stopping response inhibition in 47 children with 22q11.2DS and 36 typically developing (TD children, all ages 7-14. A cross-sectional design was used to examine age-related associations with response inhibition. When compared with TD individuals, children with 22q11.2DS demonstrated typical proactive response inhibition at all ages. By contrast, reactive response inhibition was impaired in children with 22q11.2DS relative to TD children. While older age predicted better reactive response inhibition in TD children, there was no age-related association with reactive response inhibition in children with 22q11.2DS. Closer examination of individual performance data revealed a wide range of performance abilities in older children with 22q11.2DS; some typical and others highly impaired. The results of this cross-sectional analysis suggest an impaired developmental trajectory of reactive response inhibition in some children with 22q11.2DS that might be related to atypical development of neuroanatomical systems underlying this cognitive process. As part of a larger study, this investigation might help identify risk factors for conversion to schizophrenia and lead to early diagnosis and preventive intervention.

  15. Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement

    Science.gov (United States)

    Bien-Willner, Gabriel A.; López-Terrada, Dolores; Bhattacharjee, Meena B.; Patel, Kayuri U.; Stankiewicz, Paweł; Lupski, James R.; Pfeifer, John D.; Perry, Arie

    2012-01-01

    Medulloblastoma is diagnosed histologically; treatment depends on staging and age of onset. Whereas clinical factors identify a standard- and a high-risk population, these findings cannot differentiate which standard-risk patients will relapse and die. Outcome is thought to be influenced by tumor subtype and molecular alterations. Poor prognosis has been associated with isochromosome (i)17q in some but not all studies. In most instances, molecular investigations document that i17q is not a true isochromosome but rather an isodicentric chromosome, idic(17)(p11.2), with rearrangement breakpoints mapping within the REPA/REPB region on 17p11.2. This study explores the clinical utility of testing for idic(17)(p11.2) rearrangements using an assay based on fluorescent in situ hybridization (FISH). This test was applied to 58 consecutive standard- and high-risk medulloblastomas with a 5-year minimum of clinical follow-up. The presence of i17q (ie, including cases not involving the common breakpoint), idic(17)(p11.2), and histologic subtype was correlated with clinical outcome. Overall survival (OS) and disease-free survival (DFS) were consistent with literature reports. Fourteen patients (25%) had i17q, with 10 (18%) involving the common isodicentric rearrangement. The presence of i17q was associated with a poor prognosis. OS and DFS were poor in all cases with anaplasia (4), unresectable disease (7), and metastases at presentation (10); however, patients with standard-risk tumors fared better. Of these 44 cases, tumors with idic(17)(p11.2) were associated with significantly worse patient outcomes and shorter mean DFS. FISH detection of idic(17)(p11.2) may be useful for risk stratification in standard-risk patients. The presence of this abnormal chromosome is associated with early recurrence of medulloblastoma. PMID:22573308

  16. Subthreshold Psychosis in 22q11.2 Deletion Syndrome: Multisite Naturalistic Study.

    Science.gov (United States)

    Weisman, Omri; Guri, Yael; Gur, Raquel E; McDonald-McGinn, Donna M; Calkins, Monica E; Tang, Sunny X; Emanuel, Beverly; Zackai, Elaine H; Eliez, Stephan; Schneider, Maude; Schaer, Marie; Kates, Wendy R; Antshel, Kevin M; Fremont, Wanda; Shashi, Vandana; Hooper, Stephen R; Armando, Marco; Vicari, Stefano; Pontillo, Maria; Kushan, Leila; Jalbrzikowski, Maria; Bearden, Carrie E; Cubells, Joseph F; Ousley, Opal Y; Walker, Elaine F; Simon, Tony J; Stoddard, Joel; Niendam, Tara A; van den Bree, Marianne B M; Gothelf, Doron

    2017-09-01

    Nearly one-third of individuals with 22q11.2 deletion syndrome (22q11.2DS) develop a psychotic disorder during life, most of them by early adulthood. Importantly, a full-blown psychotic episode is usually preceded by subthreshold symptoms. In the current study, 760 participants (aged 6-55 years) with a confirmed hemizygous 22q11.2 microdeletion have been recruited through 10 medical sites worldwide, as part of an international research consortium. Of them, 692 were nonpsychotic and with complete measurement data. Subthreshold psychotic symptoms were assessed using the Structured Interview for Prodromal Syndromes (SIPS). Nearly one-third of participants met criteria for positive subthreshold psychotic symptoms (32.8%), less than 1% qualified for acute positive subthreshold symptoms, and almost a quarter met criteria for negative/disorganized subthreshold symptoms (21.7%). Adolescents and young adults (13-25 years) showed the highest rates of subthreshold psychotic symptoms. Additionally, higher rates of anxiety disorders and attention deficit/hyperactivity disorder (ADHD) were found among the study participants with subthreshold psychotic symptoms compared to those without. Full-scale IQ, verbal IQ, and global functioning (GAF) scores were negatively associated with participants' subthreshold psychotic symptoms. This study represents the most comprehensive analysis reported to date on subthreshold psychosis in 22q11.2DS. Novel findings include age-related changes in subthreshold psychotic symptoms and evidence that cognitive deficits are associated with subthreshold psychosis in this population. Future studies should longitudinally follow these symptoms to detect whether and how early identification and treatment of these manifestations can improve long-term outcomes in those that eventually develop a psychotic disorder. © The Author 2017. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For

  17. Association between prematurity and the evolution of psychotic disorders in 22q11.2 deletion syndrome.

    Science.gov (United States)

    Midbari Kufert, Yael; Nachmani, Ariela; Nativ, Einat; Weizman, Abraham; Gothelf, Doron

    2016-12-01

    In this study, we report the developmental, physical and psychiatric manifestations of 22q11.2 deletion syndrome (22q11.2DS) in a large Israeli cohort, and search for a possible association between preterm birth and the risk for psychotic disorders. The study population consisted of 128 individuals with 22q11.2DS (77 male, 51 female), aged 1-55 years (mean ± SD 12.9 ± 11.0). All subjects underwent a comprehensive medical evaluation. All subjects older than 5 years (n = 104) were also evaluated psychiatrically. Overall, we found rates of physical manifestations similar to those previously reported in the literature. Psychiatric disorders were very common among our study population, with psychotic disorders occurring in 16.3 % of the psychiatrically evaluated population. We found an association between the presence of psychotic disorders and preterm birth. Our results replicate and extend the findings of a previous work and suggest that the evolution of psychosis in 22q11.2DS is a neurodevelopmental process with early obstetric and medical precursors.

  18. 2006. aasta arhitektuurikonkursid / Karen Jagodin

    Index Scriptorium Estoniae

    Jagodin, Karen, 1982-

    2006-01-01

    Toodud ka 2006. a. konkursside tulemused: Eesti Rahva Muuseumi uus hoone, Tartu Ida t. lastead, Kiviõli linnaväljak, Tartu Lutsu t. korterelamu fassaadilahendus, Paide spordihall, Pärnu piirivalvekordoni hoone, Tartu Rebase t. kortermajade kompleks, Viljandi Maagümnaasiumi juurdeehitus, Veneetsia X arhitektuuribiennaali Eesti kuraatorinäitus, betoonehitis 2005, Estonia Seltsi vana teatrimaja asukoha tähistamine, TTÜ uus raamatukogu, Maakri kvartali arhitektuurikonkursi I etapp, Viljandi Uku t. 1A Lidli kauplusehoone ja südalinna kvartali detailplaneering, Pärnu jõeäärse keskuse ideeplaneering, Karksi-Nuia keskväljak ja roheala, terasehitis 2006, Edela-Eesti loodus- ja keskkonnahariduskeskuse ehk ökomaja eskiisprojekt, puitehitis 2006

  19. 45 CFR 400.112 - Child welfare services for refugee children.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Child welfare services for refugee children. 400... RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Child Welfare Services § 400.112 Child welfare services for refugee children. (a) In...

  20. Characteristic face: a key indicator for direct diagnosis of 22q11.2 deletions in Chinese velocardiofacial syndrome patients.

    Science.gov (United States)

    Wu, Dandan; Chen, Yang; Xu, Chen; Wang, Ke; Wang, Huijun; Zheng, Fengyun; Ma, Duan; Wang, Guomin

    2013-01-01

    Velocardiofacial syndrome (VCFS) is a disease in human with an expansive phenotypic spectrum and diverse genetic mechanisms mainly associated with copy number variations (CNVs) on 22q11.2 or other chromosomes. However, the correlations between CNVs and phenotypes remain ambiguous. This study aims to analyze the types and sizes of CNVs in VCFS patients, to define whether correlations exist between CNVs and clinical manifestations in Chinese VCFS patients. In total, 55 clinically suspected Chinese VCFS patients and 100 normal controls were detected by multiplex ligation-dependent probe amplification (MLPA). The data from MLPA and all the detailed clinical features of the objects were documented and analyzed. A total of 44 patients (80.0%) were diagnosed with CNVs on 22q11.2. Among them, 43 (78.2%) presented with 22q11.2 heterozygous deletions, of whom 40 (93.0%) had typical 3-Mb deletion, and 3 (7.0%) exhibited proximal 1.5-Mb deletion; no patient was found with atypical deletion on 22q11.2. One patient (1.8%) presented with a 3-Mb duplication mapping to the typical 3-Mb region on 22q11.2, while none of the chromosomal abnormalities in the MLPA kit were found in the other 11 patients and 100 normal controls. All the 43 patients with 22q11.2 deletions displayed characteristic face and palatal anomalies; 37 of them (86.0%) had cognitive or behavioral disorders, and 23 (53.5%) suffered from immune deficiencies; 10 patients (23.3%) manifested congenital heart diseases. Interestingly, all patients with the characteristic face had 22q11.2 heterozygous deletions, but no difference in phenotypic spectrum was observed between 3-Mb and 1.5-Mb deletions. Our data suggest that the characteristic face can be used as a key indicator for direct diagnosis of 22q11.2 deletions in Chinese VCFS patients.

  1. The relationship between career decision self-efficacy and self-directed learning amongst female university students : a cross-cultural study

    OpenAIRE

    2011-01-01

    M.A. The career landscape has undergone considerable change within the past three decades (Hackett, Lent & Greenhaus, 1991; Sharf, 2002). Globalisation, the opening up of markets and rapid technological advances have produced a new world of work. Career choices and career challenges are more numerous and the career decision-making process more complex (Stead & Watson, 2006b). Baruch (2006) suggests that with these changes comes a need to address the preparation of future recruits. Accordin...

  2. Final disposal of spent nuclear fuel - regulatory system and roles of different actors during the decision process

    Energy Technology Data Exchange (ETDEWEB)

    2009-03-15

    In November 2006 Swedish Nuclear Fuels Co. applied for a license to build a plant for encapsulation of spent nuclear fuels at Oskarshamn, Sweden. The company also have plans to apply, in 2009, for a license to construct a underground repository for spent nuclear fuels. KASAM arranged a seminar in November 2006 in order to describe and discuss the licensing rules and regulations and the roles of different parties in the decision making. Another objective of the seminar was to point out possible ambiguities in this process. Another interesting question under discussion was in what ways the basic data for the decision should be produced. The seminar covered the part of the process beginning with the application for a license and ending with the government approval/rejection of the application. Most time was spent on the legal aspects of the process

  3. Final disposal of spent nuclear fuel - regulatory system and roles of different actors during the decision process

    International Nuclear Information System (INIS)

    2009-03-01

    In November 2006 Swedish Nuclear Fuels Co. applied for a license to build a plant for encapsulation of spent nuclear fuels at Oskarshamn, Sweden. The company also have plans to apply, in 2009, for a license to construct a underground repository for spent nuclear fuels. KASAM arranged a seminar in November 2006 in order to describe and discuss the licensing rules and regulations and the roles of different parties in the decision making. Another objective of the seminar was to point out possible ambiguities in this process. Another interesting question under discussion was in what ways the basic data for the decision should be produced. The seminar covered the part of the process beginning with the application for a license and ending with the government approval/rejection of the application. Most time was spent on the legal aspects of the process

  4. Transposition of the great arteries - a phenotype associated with 16p11.2 duplications?

    Science.gov (United States)

    Karunanithi, Zarmiga; Vestergaard, Else Marie; Lauridsen, Mette H

    2017-12-26

    Genetic analyses of patients with transposition of the great arteries have identified rare copy number variations, suggesting that they may be significant to the aetiology of the disease. This paper reports the identification of a 16p11.2 microduplication, a variation that has yet to be reported in association with transposition of the great arteries. The 16p11.2 microduplication is associated with autism spectrum disorder and developmental delay, but with highly variable phenotypic effects. Autism and attention deficit disorders are observed more frequently in children with congenital heart disease than in the general population. Neonatal surgery is proposed as a risk factor, but as yet unidentified genetic abnormalities should also be taken into account. Thus, congenital heart abnormalities may constitute a part of the phenotypic spectrum associated with duplications at 16p11.2. We suggest chromosomal microarray be considered part of the diagnostic work-up in patients with transposition of the great arteries.

  5. Annual Site Environmental Report: 2006

    Energy Technology Data Exchange (ETDEWEB)

    Nuckolls, H.; /SLAC

    2008-02-22

    This report provides information about environmental programs during the calendar year (CY) of 2006 at the Stanford Linear Accelerator Center (SLAC), Menlo Park, California. Activities that span the calendar year; i.e., stormwater monitoring covering the winter season of 2006/2007 (October 2006 through May 2007), are also included. Production of an annual site environmental report (ASER) is a requirement established by the United States Department of Energy (DOE) for all management and operating (M&O) contractors throughout the DOE complex. SLAC is a federally-funded research and development center with Stanford University as the M&O contractor. SLAC continued to follow the path to self-declare an environmental management system under DOE Order 450.1, 'Environmental Protection Program' and effectively applied environmental management in meeting the site's integrated safety and environmental management system goals. For normal daily activities, all SLAC managers and supervisors are responsible for ensuring that proper procedures are followed so that Worker safety and health are protected; The environment is protected; and Compliance is ensured. Throughout 2006, SLAC focused on these activities through the SLAC management systems. These systems were also the way SLAC approached implementing 'greening of the government' initiatives such as Executive Order 13148. The management systems at SLAC are effective, supporting compliance with all relevant statutory and regulatory requirements. The SLAC Office of Assurance was created during 2006 in response to DOE Order 226.1. During 2006, there were no reportable releases to the environment from SLAC operations, and there were no Notice of Violations issued to SLAC from any of the regulatory agencies that oversee SLAC. In addition, many improvements in waste minimization, recycling, stormwater drain system, groundwater restoration, and SLAC's chemical management system (CMS) were continued during

  6. Tank characterization report for single-shell tank 241-BY-112

    International Nuclear Information System (INIS)

    Baldwin, J.H.

    1997-01-01

    This document summarizes the information on the historical uses, present status, and the sampling and analysis results of waste stored in Tank 241-BY-112. This report supports the requirements of the Tri-Party Agreement Milestone M-44-10. (This tank has been designated a Ferrocyanide Watch List tank.)

  7. 34 CFR 692.112 - May a State use the funds it receives from the GAP Program to pay administrative costs?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false May a State use the funds it receives from the GAP Program to pay administrative costs? 692.112 Section 692.112 Education Regulations of the Offices of the... Assistance and How May It Be Used? § 692.112 May a State use the funds it receives from the GAP Program to...

  8. The energy market in Flanders, Belgium, in 2006

    International Nuclear Information System (INIS)

    2007-05-01

    The Flemish Regulation Entity for the Electricity and Gas market (VREG) aims at becoming the knowledge centre of the liberalised energy market in Flanders, Belgium. Knowledge must be obtained and made available to the public with respect to the market for energy. This does not only involve aspects pertaining to the physical connection of grids across the borders of districts and countries, but also the effects of economic, political and financial decisions and tendencies in Flanders and surrounding area. In the past, data on the energy market were publishes as part of the annual report. As of 2006, reporting is separated. This Energy Market Report is built up based on data that was made available by the market parties. It focuses on the various actors and their market positions as well as on the specific historical and future evolutions. Moreover, market forces are portrayed. The price evolutions of the past years are analysed. Finally, attention is paid to the growing market of certificates.(mk) [nl

  9. Progress Report Sustainable Energy 2006; Voortgangsrapportage Duurzame Daadkracht 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-02-15

    In the title program it is described how the Netherlands will fulfil the agreements that were made at the Johannesburg summit on sustainable development. The program consists of an international and a national strategy. In this document an overview is given of the results so far. The focus is on administration, energy and biological diversity. [Dutch] Het Actieprogramma Duurzame Ontwikkeling, getiteld 'Duurzame Daadkracht' (2003), is de Nederlandse uitwerking van de afspraken die in 2002 op de World Summit on Sustainable Development (WSSD) in Johannesburg zijn gemaakt. In de voorliggende voortgangsrapportage over 2006 worden de vorderingen in het bereiken van de ambities van het rijk, zowel voor het nationale als het internationale deel, verder uitgediept. Daarbij is dit jaar gekozen voor een meer thematische benadering dan in voorgaande rapportages, mede naar aanleiding van het Algemeen Overleg van 4 oktober 2006 over de rapportage 2005. De thema's zijn bestuur, energie en biodiversiteit. In hoofdstuk 2 wordt een beschouwing gegeven over de aansturing van duurzame ontwikkeling, een thema dat in 2006 vooral in internationale bijeenkomsten veel aandacht kreeg. Hoofdstuk 3 belicht het thema duurzame energiehuishouding. In hoofdstuk 4 wordt het thema natuurlijke hulpbronnen en biodiversiteit nader bezien. Hoofdstuk 5 geeft informatie over een aantal relevante instrumenten, waaronder de internationale partnerschappen, innovatieprojecten en de peer review van het Nederlandse duurzaamheidsbeleid. Hoofdstuk 6 presenteert de voortgang in duurzaam inkopen bij de Rijksoverheid en illustreert aan de hand van een aantal voorbeelden de wijze waarop vijf ministeries concreet invulling geven aan duurzame ontwikkeling binnen de eigen organisatie. De bijlage bevat een afkortingenregister.

  10. Rare genome-wide copy number variation and expression of schizophrenia in 22q11.2 deletion syndrome

    NARCIS (Netherlands)

    Bassett, Anne S.; Lowther, Chelsea; Merico, Daniele; Costain, Gregory; Chow, Eva W C; Van Amelsvoort, Therese; McDonald-Mcginn, Donna M.; Gur, Raquel E.; Swillen, Ann; van den Bree, Marianne B M; Murphy, Kieran C.; Gothelf, Doron; Bearden, Carrie E.; Eliez, Stephan; Kates, Wendy R.; Philip, Nicole; Sashi, Vandana; Campbell, Linda E.; Vorstman, Jacob; Cubells, Joseph; Repetto, Gabriela M.; Simon, Tony J.; Boot, Erik; Heung, Tracy; Evers, Rens; Vingerhoets, Claudia; Van Duin, Esther; Zackai, Elaine; Vergaelen, Elfi; Devriendt, Koen; Vermeesch, Joris R.; Owen, Michael J; Murphy, Clodagh M.; Michaelovosky, Elena; Kushan, Leila; Schneider, Maude; Fremont, Wanda; Busa, Tiffany; Hooper, Stephen R.; McCabe, Kathryn; Duijff, Sasja; Isaev, Karin; Pellecchia, Giovanna; Wei, John; Gazzellone, Matthew J.; Scherer, Stephen W.; Emanuel, Beverly S.; Guo, Tingwei; Morrow, Bernice E.; Marshall, Christian R.

    2017-01-01

    Objective: Chromosome 22q11.2 deletion syndrome (22q11.2DS) is associated with a more than 20-fold increased risk for developing schizophrenia. The aim of this studywas to identify additional genetic factors (i.e., "second hits") that may contribute to schizophrenia expression. Method: Through an

  11. The Type II supernovae 2006V and 2006au: two SN 1987A-like events

    DEFF Research Database (Denmark)

    Taddia, F.; Stritzinger, M. D.; Sollerman, J.

    2012-01-01

    1987A. Methods. Optical and near-infrared (NIR) light curves, and optical spectroscopy of SNe 2006V and 2006au are presented. These observations are compared to those of SN 1987A, and are used to estimate properties of their progenitors. Results. Both objects exhibit a slow rise to maximum and light...

  12. ANDRA, 2006 activity report

    International Nuclear Information System (INIS)

    2006-01-01

    The French national agency of radioactive waste management (ANDRA) was marked in 2006 by two outstanding events: the publication of the national inventory of radioactive wastes and valorisable materials, and the vote of the law from June 28, 2006 relative to the sustainable management of radioactive wastes and materials. This road-map law has an impact on ANDRA's activities for the coming years. This activity report presents several 2006 highlights of ANDRA's missions as well: the public service mission, the by-law about the effluents of the Aube plant for the storage of low-medium activity wastes, the building of the first 'double-cell' at the very-low activity waste storage plant of Aube, the research studies about the project of deep underground disposal of high-medium activity, long-living wastes, and the public information about ANDRA's technical and scientific know-how. The management and financial reports are attached in appendix. (J.S.)

  13. Orçamento empresarial: levantamento da produção científica no período de 1995 a 2006 Business budget: a survey of scientific production in the period from 1995 to 2006

    Directory of Open Access Journals (Sweden)

    Rita Mara Leite

    2008-08-01

    Full Text Available Esta pesquisa aborda a produção científica (teses e dissertações na área de orçamento empresarial no período de 1995 a 2006. O objetivo é resgatar estudos que versam orçamento empresarial. As informações foram coletadas nos programas brasileiros de mestrado e doutorado em ciências contábeis, reconhecidos e recomendados pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES. Para o estudo e interpretação dos dados utilizou-se a análise de conteúdo fundamentada em Bardin. Foram analisados todos os títulos das 1257 dissertações e 112 teses com categorização a priori nas subáreas temáticas: orçamento público, orçamento empresarial, orçamento operacional, orçamento financeiro, considerando-se a presença ou ausência do termo "orçamento". Verificou-se que, do total de 1257 dissertações, apenas 27 dissertações abordam o tema orçamento, sendo que 16 enfocam especificamente o orçamento empresarial, representando 1,27% da produção científica; as outras 11 tratam de orçamento público. Quanto às teses, das 112 encontradas, apenas 1 aborda o orçamento na área pública. Os resultados revelam que o tema "orçamento" é muito pouco investigado entre a produção científica mais expressiva em instituições de ensino superior. Infere-se que a baixa produção na área está relacionada com as dificuldades dos pesquisadores na obtenção de dados para o desenvolvimento da pesquisa empírica, pelo fato de as informações relativas ao processo orçamentário serem estratégicas para as organizações. A abordagem mais freqüente das pesquisas é o estudo da aplicação dos orçamentos, mais precisamente voltado a casos únicos, o que demonstra a preocupação ou necessidade de as universidades constatarem como as empresas fazem o orçamento na prática. Na área pública, as pesquisas abordaram, com mais freqüência, o orçamento em órgãos da administração pública.This research looks at

  14. Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome

    DEFF Research Database (Denmark)

    Starnawska, A; Hansen, C S; Sparsø, T

    2017-01-01

    Individuals with 22q11.2 deletion syndrome (DS) have an increased risk of comorbid mental disorders including schizophrenia, attention deficit hyperactivity disorder, depression, as well as intellectual disability. Although most 22q11.2 deletion carriers have the long 3-Mb form of the hemizygous...... deletion, there remains a large variation in the development and progression of psychiatric disorders, which suggests that alternative factors contribute to the pathogenesis. In this study we investigated whether neonatal DNA methylation signatures in individuals with the 22q11.2 deletion associate...

  15. 40 CFR 112.3 - Requirement to prepare and implement a Spill Prevention, Control, and Countermeasure Plan.

    Science.gov (United States)

    2010-07-01

    ... § 112.1(b), you must prepare and implement a Plan within six months after you begin operations. (c) If... per day, or at the nearest field office if the facility is not so attended, and (2) Have the Plan... discharges as described in § 112.1(b) that are the result of natural disasters, acts of war, or terrorism...

  16. Powernext Day-AheadTM statistics - June 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the June 30, 2006 update of Powernext Day-Ahead TM statistics: daily traded volumes and base-load prices from November 2001 to June 2006, monthly overview from June 2005 to June 2006 (volumes and prices), weekly overview from March to June 2006 (volumes and prices), daily and hourly overview and market resilience for June 2006, power consumption in May and June 2006 (average consumption, average forecasted consumption and average price on Powernext Day-Ahead TM ), power consumption on the French hub from July 2005 to May 2006 and Powernext Day-Ahead TM prices, transfer capacities in June 2006 (auction results for France-Germany, France-Belgium, France-UK, France-Spain and France-Italy, and daily capacity allocation for France-Switzerland), temperature variations in France from January 2005 to June 2006 and base-load Powernext Day-Ahead TM prices, and balancing mechanism for April, May and June 2006 (half-hourly imbalance settlement prices). (J.S.)

  17. UV and infrared absorption spectra, atmospheric lifetimes, and ozone depletion and global warming potentials for CCl2FCCl2F (CFC-112, CCl3CClF2 (CFC-112a, CCl3CF3 (CFC-113a, and CCl2FCF3 (CFC-114a

    Directory of Open Access Journals (Sweden)

    M. E. Davis

    2016-07-01

    Full Text Available The potential impact of CCl2FCF3 (CFC-114a and the recently observed CCl2FCCl2F (CFC-112, CCl3CClF2 (CFC-112a, and CCl3CF3 (CFC-113a chlorofluorocarbons (CFCs on stratospheric ozone and climate is presently not well characterized. In this study, the UV absorption spectra of these CFCs were measured between 192.5 and 235 nm over the temperature range 207–323 K. Precise parameterizations of the UV absorption spectra are presented. A 2-D atmospheric model was used to evaluate the CFC atmospheric loss processes, lifetimes, ozone depletion potentials (ODPs, and the associated uncertainty ranges in these metrics due to the kinetic and photochemical uncertainty. The CFCs are primarily removed in the stratosphere by short-wavelength UV photolysis with calculated global annually averaged steady-state lifetimes (years of 63.6 (61.9–64.7, 51.5 (50.0–52.6, 55.4 (54.3–56.3, and 105.3 (102.9–107.4 for CFC-112, CFC-112a, CFC-113a, and CFC-114a, respectively. The range of lifetimes given in parentheses is due to the 2σ uncertainty in the UV absorption spectra and O(1D rate coefficients included in the model calculations. The 2-D model was also used to calculate the CFC ozone depletion potentials (ODPs with values of 0.98, 0.86, 0.73, and 0.72 obtained for CFC-112, CFC-112a, CFC-113a, and CFC-114a, respectively. Using the infrared absorption spectra and lifetimes determined in this work, the CFC global warming potentials (GWPs were estimated to be 4260 (CFC-112, 3330 (CFC-112a, 3650 (CFC-113a, and 6510 (CFC-114a for the 100-year time horizon.

  18. Fondihaldurid 2006

    Index Scriptorium Estoniae

    2005-01-01

    Investeerimisfondide LHV-Seesam Varahaldus, Hansa Investeerimisfondid, SEB Ühispanga Fondid, Trigon Kesk- ja Ida-Euroopa Fond, Trigon Uus Euroopa Väikeettevõtete Fond, Trigon Teise Laine Fond, SEB Ühispanga Võlakirjafond ja LHV Kauplemismandaat juhid tutvustavad fondide tegevust 2005. aastal ja prognoosivad investeerimisvõimalusi oma piirkonnas aastal 2006

  19. A highly penetrant form of childhood apraxia of speech due to deletion of 16p11.2.

    Science.gov (United States)

    Fedorenko, Evelina; Morgan, Angela; Murray, Elizabeth; Cardinaux, Annie; Mei, Cristina; Tager-Flusberg, Helen; Fisher, Simon E; Kanwisher, Nancy

    2016-02-01

    Individuals with heterozygous 16p11.2 deletions reportedly suffer from a variety of difficulties with speech and language. Indeed, recent copy-number variant screens of children with childhood apraxia of speech (CAS), a specific and rare motor speech disorder, have identified three unrelated individuals with 16p11.2 deletions. However, the nature and prevalence of speech and language disorders in general, and CAS in particular, is unknown for individuals with 16p11.2 deletions. Here we took a genotype-first approach, conducting detailed and systematic characterization of speech abilities in a group of 11 unrelated children ascertained on the basis of 16p11.2 deletions. To obtain the most precise and replicable phenotyping, we included tasks that are highly diagnostic for CAS, and we tested children under the age of 18 years, an age group where CAS has been best characterized. Two individuals were largely nonverbal, preventing detailed speech analysis, whereas the remaining nine met the standard accepted diagnostic criteria for CAS. These results link 16p11.2 deletions to a highly penetrant form of CAS. Our findings underline the need for further precise characterization of speech and language profiles in larger groups of affected individuals, which will also enhance our understanding of how genetic pathways contribute to human communication disorders.

  20. 22q11.2 deletion status and disease burden in children and adolescents with tetralogy of Fallot.

    Science.gov (United States)

    Mercer-Rosa, Laura; Paridon, Stephen M; Fogel, Mark A; Rychik, Jack; Tanel, Ronn E; Zhao, Huaqing; Zhang, Xuemei; Yang, Wei; Shults, Justine; Goldmuntz, Elizabeth

    2015-02-01

    Patients with repaired tetralogy of Fallot experience variable outcomes for reasons that are incompletely understood. We hypothesize that genetic variants contribute to this variability. We sought to investigate the association of 22q11.2 deletion status with clinical outcome in patients with repaired tetralogy of Fallot. We performed a cross-sectional study of tetralogy of Fallot subjects who were tested for 22q11.2 deletion, and underwent cardiac magnetic resonance, exercise stress test, and review of medical history. We studied 165 subjects (12.3±3.1 years), of which 30 (18%) had 22q11.2 deletion syndrome (22q11.2DS). Overall, by cardiac magnetic resonance the right ventricular ejection fraction was 60±8%, pulmonary regurgitant fraction was 34±17%, and right ventricular end-diastolic volume was 114±39 cc/m(2). On exercise stress test, maximum oxygen consumption was 76±16% predicted. Despite comparable right ventricular function and pulmonary regurgitant fraction, on exercise stress test the 22q11.2DS had significantly lower percent predicted: forced vital capacity (61.5±16 versus 80.5±14; Ptetralogy of Fallot. These findings may provide avenues for intervention to improve outcomes, and should be re-evaluated longitudinally because these associations may become more pronounced with time. © 2015 American Heart Association, Inc.

  1. Final disposal of spent nuclear fuels - regulations and the roles of different stakeholders during the decision making process

    International Nuclear Information System (INIS)

    2007-05-01

    In November 2006 Swedish Nuclear Fuels Co. applied for a license to build a plant for encapsulation of spent nuclear fuels at Oskarshamn, Sweden. The company also have plans to apply, in 2009, for a license to construct a underground repository for spent nuclear fuels. KASAM arranged a seminar in November 2006 in order to describe and discuss the licensing rules and regulations and the roles of different parties in the decision making. Another objective of the seminar was to point out possible ambiguities in this process. Another interesting question under discussion was in what ways the basic data for the decision should be produced. The seminar covered the part of the process beginning with the application for a license and ending with the government approval/rejection of the application. Most time was spent on the legal aspects of the process

  2. Does unconscious thought outperform conscious thought on complex decisions? A further examination

    Directory of Open Access Journals (Sweden)

    Todd J. Thorsteinson

    2009-04-01

    Full Text Available Two experiments examined the benefits of unconscious thought on complex decisions (Dijksterhuis, 2004. Experiment 1 attempted to replicate and extend past research by examining the effect of providing reasons prior to rating the options. Results indicated no significant differences between the conditions. Experiment 2 attempted to replicate the findings of Dijksterhuis, Bos, Nordgren, and van Baaren (2006 and determine if a memory aid could overcome the limitations of conscious thought on complex tasks. Results revealed that a memory aid improved decisions compared to the conscious thought condition. Participants in the unconscious thought condition did not perform significantly better than did participants in the conscious thought condition.

  3. 3. quarter 2006 sales revenue

    International Nuclear Information System (INIS)

    2006-10-01

    This document presents the sales revenue of the 3. quarter 2006 for the Group AREVA. The sales revenues for the first nine months of 2006 are up by 8,1% to 7,556 millions euros; the nuclear operations are up by 5,2% reflecting strong performance in the front end division; the transmission and distribution division is up by 14%. (A.L.B.)

  4. Séminaire de l'enseignement technique : Forum AutoCAD 2006 et AutoCAD Mechanical 2006 - French version only

    CERN Multimedia

    Davide Vitè

    2005-01-01

    Jeudi 17 novembre 2005 de 14:30 à 16:30 - Training Centre Auditorium Forum AutoCAD 2006 et AutoCAD Mechanical 2006 CADSCHOOL, CH-1207 GENEVE, Suisse Ce nouveau séminaire de l'Enseignement technique, organisé en forme de forum et en collabora- tion avec TS-MME et notre entreprise partenaire en formation, sera consacré à la présentation de la nouvelle version d'AutoCAD, AutoCAD 2006 et AutoCAD Mechanical 2006, disponible au CERN. Au programme : Présentation d'AutoCAD Mechanical 2006 Améliorations par rapport à AutoCAD Mechanical 6 Power Pack Questions - Réponses Langue: Français. Séminaire libre, sans inscription. Organisateurs: Manfred Mayer / TS-MME / 74499 ; Davide Vitè / HR-PMD / 75141 Pour plus d'information, veuillez SVP visiter les pages des Séminaires de l'Enseignement Technique à l'adresse http://www.cern.ch/TechnicalTraining/special/TTseminars.asp . ENSEIGNEMENT TECHNIQUE TECHNICAL TRAINING technical.training@cern.ch

  5. The phosphoric acid leak from the wreck of the MV Ece in the English Channel in 2006: Assessment with a ship of opportunity, an operational ecosystem model and historical data

    Energy Technology Data Exchange (ETDEWEB)

    Kelly-Gerreyn, Boris A. [National Oceanography Centre, Southampton, Waterfront Campus, European Way, Southampton SO14 3ZH (United Kingdom)]. E-mail: bag@noc.soton.ac.uk; Hydes, David J. [National Oceanography Centre, Southampton, Waterfront Campus, European Way, Southampton SO14 3ZH (United Kingdom); Hartman, Mark C. [National Oceanography Centre, Southampton, Waterfront Campus, European Way, Southampton SO14 3ZH (United Kingdom); Siddorn, John [Ocean Forecasting Research and Development, Met Office, FitzRoy Road, Exeter EX1 3PB (United Kingdom); Hyder, Patrick [Ocean Forecasting Research and Development, Met Office, FitzRoy Road, Exeter EX1 3PB (United Kingdom); Holt, Martin W. [Ocean Forecasting Research and Development, Met Office, FitzRoy Road, Exeter EX1 3PB (United Kingdom)

    2007-07-15

    This study evaluates the ship of opportunity (Ferrybox) concept for both sustained monitoring of UK shelf sea waters and numerical model validation. Release of phosphate from the wreck of a chemical tanker (MV Ece) in the western English Channel (49.73{sup o}N, 3.25{sup o}W) in March 2006 is used to demonstrate the importance of sustained observations in decision support systems and policy development. The Ferrybox system continuously collects sea surface (5 m) data from a suite of autonomous electronic sensors installed on a passenger ferry operating year-round between Portsmouth (UK) and Bilbao (Spain). The detection of anomalously high concentrations of phosphate (1.54 mmol m{sup -3}, four times the usual level) and onset of phytoplankton growth close to the wreck site in March 2006 was placed in the context of multiple years of measurements (phosphate, nitrate, silicate and chlorophyll) collected from the Ferrybox system (2003-2006) and the long-term time series station E1 (50.03{sup o}N, 4.65{sup o}W, 1930-1987) in the English Channel. With regard to decision support, release of phosphate from the tanker is unlikely to pose a threat as phytoplankton growth at the end of winter is not unusual in this region and dissolved inorganic nitrogen rather than phosphate (DIN:DIP = 10-18) is likely to ultimately limit algal growth in spring 2006. With regard to policy development, the Oslo and Paris (OSPAR) commissions recommendation of sampling every three years in 'non-problem areas' is likely to provide statistically inadequate data, given the interannual and decadal variability identified in the Ferrybox and E1 data: the Ferrybox data show that oceanic winter nutrient concentrations varied by 35-50% between 2003/2004 and 2005/2006 due to deeper mixing of water off-shelf in early 2005/2006 and comparisons between the Ferrybox and E1 years show that the western English Channel is currently experiencing a low in phosphate concentrations similar to those in the

  6. The phosphoric acid leak from the wreck of the MV Ece in the English Channel in 2006: Assessment with a ship of opportunity, an operational ecosystem model and historical data

    International Nuclear Information System (INIS)

    Kelly-Gerreyn, Boris A.; Hydes, David J.; Hartman, Mark C.; Siddorn, John; Hyder, Patrick; Holt, Martin W.

    2007-01-01

    This study evaluates the ship of opportunity (Ferrybox) concept for both sustained monitoring of UK shelf sea waters and numerical model validation. Release of phosphate from the wreck of a chemical tanker (MV Ece) in the western English Channel (49.73 o N, 3.25 o W) in March 2006 is used to demonstrate the importance of sustained observations in decision support systems and policy development. The Ferrybox system continuously collects sea surface (5 m) data from a suite of autonomous electronic sensors installed on a passenger ferry operating year-round between Portsmouth (UK) and Bilbao (Spain). The detection of anomalously high concentrations of phosphate (1.54 mmol m -3 , four times the usual level) and onset of phytoplankton growth close to the wreck site in March 2006 was placed in the context of multiple years of measurements (phosphate, nitrate, silicate and chlorophyll) collected from the Ferrybox system (2003-2006) and the long-term time series station E1 (50.03 o N, 4.65 o W, 1930-1987) in the English Channel. With regard to decision support, release of phosphate from the tanker is unlikely to pose a threat as phytoplankton growth at the end of winter is not unusual in this region and dissolved inorganic nitrogen rather than phosphate (DIN:DIP = 10-18) is likely to ultimately limit algal growth in spring 2006. With regard to policy development, the Oslo and Paris (OSPAR) commissions recommendation of sampling every three years in 'non-problem areas' is likely to provide statistically inadequate data, given the interannual and decadal variability identified in the Ferrybox and E1 data: the Ferrybox data show that oceanic winter nutrient concentrations varied by 35-50% between 2003/2004 and 2005/2006 due to deeper mixing of water off-shelf in early 2005/2006 and comparisons between the Ferrybox and E1 years show that the western English Channel is currently experiencing a low in phosphate concentrations similar to those in the 1960s. The importance of

  7. The phosphoric acid leak from the wreck of the MV Ece in the English Channel in 2006: Assessment with a ship of opportunity, an operational ecosystem model and historical data.

    Science.gov (United States)

    Kelly-Gerreyn, Boris A; Hydes, David J; Hartman, Mark C; Siddorn, John; Hyder, Patrick; Holt, Martin W

    2007-07-01

    This study evaluates the ship of opportunity (Ferrybox) concept for both sustained monitoring of UK shelf sea waters and numerical model validation. Release of phosphate from the wreck of a chemical tanker (MV Ece) in the western English Channel (49.73 degrees N, 3.25 degrees W) in March 2006 is used to demonstrate the importance of sustained observations in decision support systems and policy development. The Ferrybox system continuously collects sea surface (5m) data from a suite of autonomous electronic sensors installed on a passenger ferry operating year-round between Portsmouth (UK) and Bilbao (Spain). The detection of anomalously high concentrations of phosphate (1.54mmolm(-3), four times the usual level) and onset of phytoplankton growth close to the wreck site in March 2006 was placed in the context of multiple years of measurements (phosphate, nitrate, silicate and chlorophyll) collected from the Ferrybox system (2003-2006) and the long-term time series station E1 (50.03 degrees N, 4.65 degrees W, 1930-1987) in the English Channel. With regard to decision support, release of phosphate from the tanker is unlikely to pose a threat as phytoplankton growth at the end of winter is not unusual in this region and dissolved inorganic nitrogen rather than phosphate (DIN:DIP=10-18) is likely to ultimately limit algal growth in spring 2006. With regard to policy development, the Oslo and Paris (OSPAR) commissions recommendation of sampling every three years in "non-problem areas" is likely to provide statistically inadequate data, given the interannual and decadal variability identified in the Ferrybox and E1 data: the Ferrybox data show that oceanic winter nutrient concentrations varied by 35-50% between 2003/2004 and 2005/2006 due to deeper mixing of water off-shelf in early 2005/2006 and comparisons between the Ferrybox and E1 years show that the western English Channel is currently experiencing a low in phosphate concentrations similar to those in the 1960s. The

  8. Detection of Hb Rothschild HBB: c.[112T>A or 112T>C], Through High Index of Suspicion on Abnormal Pulse Oximetry.

    Science.gov (United States)

    Alli, Nazeer A; Wessels, Piet; Rampersad, Narisha; Clark, Barnaby E; Thein, Swee Lay

    2017-03-01

    We describe a case with a low oxygen affinity hemoglobin (Hb) variant who presented with cyanosis in the absence of cardiopulmonary disease. The patient, a 27-year-old pregnant female (P1G2), complained of a productive cough and bluish discoloration of the lips that started 3 days prior to seeking attention. She had no previous episodes and has generally been in good health. A positive family history of cyanosis was obtained in one sibling. Systematic examination, notably the cardiorespiratory system, revealed no abnormalities. The arterial Hb oxygen saturation (SpO 2 ) on pulse oximetry was 81.0% and Hb separation studies revealed an Hb variant identified as Hb Rothschild [β37(C3)Trp→Arg] (HBB: c.[112 T>A or 112 T>C]) by gene sequencing. The amino acid substitution (Trp→Arg) is an important contact point at the α1β2 interface and favors a T-quaternary state of the Hb tetramer. This leads to a low oxygen affinity state, which results in premature release of oxygen and drop in oxygen saturation. In the absence of cardiopulmonary disease, a decreased oxygen saturation reading, with or without cyanosis, should arouse suspicion for a possible dysHb.

  9. Characterization of the past and current duplication activities in the human 22q11.2 region

    Directory of Open Access Journals (Sweden)

    Morrow Bernice

    2011-01-01

    Full Text Available Abstract Background Segmental duplications (SDs on 22q11.2 (LCR22, serve as substrates for meiotic non-allelic homologous recombination (NAHR events resulting in several clinically significant genomic disorders. Results To understand the duplication activity leading to the complicated SD structure of this region, we have applied the A-Bruijn graph algorithm to decompose the 22q11.2 SDs to 523 fundamental duplication sequences, termed subunits. Cross-species syntenic analysis of primate genomes demonstrates that many of these LCR22 subunits emerged very recently, especially those implicated in human genomic disorders. Some subunits have expanded more actively than others, and young Alu SINEs, are associated much more frequently with duplicated sequences that have undergone active expansion, confirming their role in mediating recombination events. Many copy number variations (CNVs exist on 22q11.2, some flanked by SDs. Interestingly, two chromosome breakpoints for 13 CNVs (mean length 65 kb are located in paralogous subunits, providing direct evidence that SD subunits could contribute to CNV formation. Sequence analysis of PACs or BACs identified extra CNVs, specifically, 10 insertions and 18 deletions within 22q11.2; four were more than 10 kb in size and most contained young AluYs at their breakpoints. Conclusions Our study indicates that AluYs are implicated in the past and current duplication events, and moreover suggests that DNA rearrangements in 22q11.2 genomic disorders perhaps do not occur randomly but involve both actively expanded duplication subunits and Alu elements.

  10. Progress report on recommendations of the Flaring Project Team

    International Nuclear Information System (INIS)

    Macken, C.

    1999-01-01

    Part of the mandate of the Clean Air Strategic Alliance (CASA) is to share decision-making responsibility for air quality management with the government of Alberta, through the ministries of Environmental Protection, Energy, and Health, and the Alberta Energy and Utilities Board (EUB). CASA's vision for air quality in Alberta is that 'the air will be odourless, tasteless, look clear, and have no measurable short- or long-term adverse effects on people, animals, or the environment'. In 1997, CASA approved the establishment of the Flaring Project Team in response to public concern about potential and observed impacts associated with flaring of solution gas. Members of that team established a framework for the management of solution gas flaring. Their long-term goal is to eliminate routine flaring of solution gas. The Project Team assessed existing information on solution gas flaring, including technologies, efficiencies, emissions and impacts. Alternative technologies were also reviewed along with biological and health effects of solution gas flaring. A list of data gaps and research needs was compiled in order to help with the development of the Team's recommendations. The Team's final report was delivered in June 1998. It was recommended that the following policy objective hierarchy be used to guide decisions related to routine solution gas flaring: (1) eliminate routine solution gas flaring, (2) reduce volumes of gas flared, and (3) improve the efficiency of flares. By way of progress the Project Team was able to report that in March, 1999, the EUB issued a draft interim directive to address upstream petroleum industry flaring. The draft Directive incorporates the recommendations from the CASA Flaring Project Team with respect to management of solution gas flaring. In December 1998, changes to the royalty structure to encourage the productive use of flare gas have been announced by the Alberta Department of Energy and Alberta Environmental protection, thus

  11. National fuel-treatment budgeting in US federal agencies: capturing opportunities for transparent decision-making

    Science.gov (United States)

    Keith M. Reynolds; Paul F. Hessburg; Robert E. Keane; James P. Menakis

    2009-01-01

    The Ecosystem Management Decision Support (EMDS) system has been used by the US Department of Agriculture, Forest Service and Bureaus of the Department of the Interior since 2006 to evaluate wildfire potential across all administrative units in the continental US, and to establish priorities for allocating fuel-treatment budgets. This article discusses an EMDS fuels-...

  12. Parental Rearing Behavior Prospectively Predicts Adolescents' Risky Decision-Making and Feedback-Related Electrical Brain Activity

    Science.gov (United States)

    Euser, Anja S.; Evans, Brittany E.; Greaves-Lord, Kirstin; Huizink, Anja C.; Franken, Ingmar H. A.

    2013-01-01

    The present study examined the role of parental rearing behavior in adolescents' risky decision-making and the brain's feedback processing mechanisms. Healthy adolescent participants ("n" = 110) completed the EMBU-C, a self-report questionnaire on perceived parental rearing behaviors between 2006 and 2008 (T1). Subsequently, after an…

  13. Perceived Need for a Parental Decision Aid for the HPV Vaccine: Content and Format Preferences

    Science.gov (United States)

    Lechuga, Julia; Swain, Geoffrey; Weinhardt, Lance S.

    2014-01-01

    The human papillomavirus (HPV) is a precursor of cervical cancer. In 2006, the Federal Drug Administration licensed a vaccine to protect against four types of HPV. Three years postlicensure of the vaccine, HPV vaccination is still fraught with controversy. To date, research suggests that contrary to popular notions, parents are less concerned with controversies on moral issues and more with uncertainty regarding because long-term safety of a drug is resolved after licensure. This study was designed to understand whether mothers from diverse ethnicities perceive a need for a decision support tool. Results suggest that the design of a culturally tailored decision support tool may help guide parents through the decision-making process. PMID:21444922

  14. Perceived need of a parental decision aid for the HPV vaccine: content and format preferences.

    Science.gov (United States)

    Lechuga, Julia; Swain, Geoffrey; Weinhardt, Lance S

    2012-03-01

    The human papillomavirus (HPV) is a precursor of cervical cancer. In 2006, the Federal Drug Administration licensed a vaccine to protect against four types of HPV. Three years postlicensure of the vaccine, HPV vaccination is still fraught with controversy. To date, research suggests that contrary to popular notions, parents are less concerned with controversies on moral issues and more with uncertainty regarding because long-term safety of a drug is resolved after licensure. This study was designed to understand whether mothers from diverse ethnicities perceive a need for a decision support tool. Results suggest that the design of a culturally tailored decision support tool may help guide parents through the decision-making process.

  15. Upstream petroleum industry flaring guide : review draft

    International Nuclear Information System (INIS)

    1999-03-01

    The Alberta requirements and expectations for upstream petroleum flaring are presented. Flaring is associated with a wide range of energy activities including oil and gas well drilling and well completion operations. The guide incorporates the recommendations made to the Alberta Energy and Utilities Board (EUB) in June 1998 by the multi-stakeholder Clean Air Strategic Alliance (CASA) on associated or solution gas flaring. Additional requirements which address flaring issues not covered in the CASA report are also included in this guide. The Guide requires a 15 per cent reduction in solution gas flare volume by the end of year 2000 from the 1996 baseline, and a 25 per cent reduction by the end of 2001. The Guide prescribes new flare performance requirements for all flares, within three years for existing solution gas flares, five years for flares at other existing permanent facilities. It sets personal consultation and public notification requirements for new and existing solution gas batteries, and new sulphur recovery requirements for facilities not covered by existing EUB regulations. The Guide also addresses the question of conflict resolution to deal with flaring concerns, the release of flaring and venting data, the proposed reduction of flare limits, progress towards minimizing requirements for electricity generators using otherwise flared gas, annual reporting to the EUB, and management framework review in 2001

  16. CERN Technical Training 2006: Introduction à Dreamweaver MX (26-27 juillet 2006)

    CERN Multimedia

    2006-01-01

    CERN Enseignement technique 2006: Introduction à Dreamweaver MX (26-27 juillet 2006) Learning for the LHC! Une nouvelle session du cours pratique Introduction à Dreamweaver MX est proposée à l'ensemble du personnel par le service de l'Enseignement technique. Cette session aura lieu en français mercredi 26 et jeudi 27 juillet 2006. Objectifs: Maîtriser les différentes fonctions de base de Dreamweaver MX pour créer et gérer des pages ou des sites web. Programme: L'interface Dreamweaver MX. Images, couleurs et fonds. Ajouter des liens. Présenter des données en tables. Utiliser les tables pour la mise en page. L'Interface mise en page. L'image réactive. Les tags META et les moteurs de recherche. Les formulaires. Les éléments dynamiques. Boutons dynamiques. Boutons flash et texte. La barre de navigation. Les styles HTML. Feuilles de style. Positionnement par couches. Gestion du site. Révision générale et évaluation. Durée: 2 jours. Coût estimé: entre 750.- et 350.- CHF par personne, se...

  17. ISEA2006 Kalifornias

    Index Scriptorium Estoniae

    2006-01-01

    San Jose rahvusvahelisel kunstifestivalil ZeroOne koos elektroonilise kunsti sümpoosioniga ISEA2006 esindas Eestit Mare Tralla projektiga "Kõigi rahvaste sõprus". Mare Tralla jätkab doktoriõppes Westminsteri Ülikoolis

  18. Terasehitis 2006

    Index Scriptorium Estoniae

    2006-01-01

    Eesti Teraskonstruktsiooniühing kuulutas välja konkursi "Terasehitis 2006" võitjad. Tervikobjekti auhinna sai Tartu spordimaja A. Le Coq Sport (arhitekt Eero Palm); insenerliku lahenduse ja teostuse auhinna pälvisid Riga Arena hokihalli katusekonstruktsioonid ning arhitektuurse idee auhind läks Eesti Panga galeriile (arhitektuuribüroo Urbanmark). Kalju Looritsa kommentaarid

  19. Motion of 1/3<111> dislocations on Σ3 (112) twin boundaries in nanotwinned copper

    Energy Technology Data Exchange (ETDEWEB)

    Lu, N.; Du, K., E-mail: kuidu@imr.ac.cn [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Beijing National Center for Electron Microscopy, Tsinghua University, Beijing 100084 (China); Lu, L.; Ye, H. Q. [Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China)

    2014-01-14

    The atomic structure of Σ3 (112) ITBs in nanotwinned Cu is investigated by using aberration-corrected high resolution transmission electron microscopy (HRTEM) and in situ HRTEM observations. The Σ3 (112) ITBs are consisted of periodically repeated three partial dislocations. The in situ HRTEM results show that 1/3[111] partial dislocation moves on the Σ3 (112) incoherent twin boundary (ITB), which was accompanied by a migration of the ITB. A dislocation reaction mechanism is proposed for the motion of 1/3[111] Frank partial dislocation, in which the 1/3[111] partial dislocation exchanges its position with twin boundary dislocations in sequence. In this way, the 1/3[111] dislocation can move on the incoherent twin boundary in metals with low stacking fault energy. Meanwhile, the ITB will migrate in its normal direction accordingly. These results provide insight into the reaction mechanism of 1/3[111] dislocations and ITBs and the associated migration of ITBs.

  20. Comparative study of polar and semipolar (112¯2) InGaN layers grown by metalorganic vapour phase epitaxy

    International Nuclear Information System (INIS)

    Dinh, Duc V.; Zubialevich, V. Z.; Oehler, F.; Kappers, M. J.; Humphreys, C. J.; Alam, S. N.; Parbrook, P. J.; Caliebe, M.; Scholtz, F.

    2014-01-01

    InGaN layers were grown simultaneously on (112 ¯ 2) GaN and (0001) GaN templates by metalorganic vapour phase epitaxy. At higher growth temperature (≥750 °C), the indium content ( ¯ 2) and (0001) InGaN layers was similar. However, for temperatures less than 750 °C, the indium content of the (112 ¯ 2) InGaN layers (15%–26%) were generally lower than those with (0001) orientation (15%–32%). The compositional deviation was attributed to the different strain relaxations between the (112 ¯ 2) and (0001) InGaN layers. Room temperature photoluminescence measurements of the (112 ¯ 2) InGaN layers showed an emission wavelength that shifts gradually from 380 nm to 580 nm with decreasing growth temperature (or increasing indium composition). The peak emission wavelength of the (112 ¯ 2) InGaN layers with an indium content of more than 10% blue-shifted a constant value of ≈(50–60) nm when using higher excitation power densities. This blue-shift was attributed to band filling effects in the layers.

  1. State of the Environment Report of the Slovak Republic 2006

    International Nuclear Information System (INIS)

    Anon

    2008-01-01

    Environmental awareness is to be raised also through regular information on the state of environment, which forms the basis for political decisions to achieve the objectives of the National strategy for sustainable development, control and evaluation of outcomes of the national environmental policy and sectoral integration strategies. State of the Environment Report in the Slovak Republic in 2006 is only one of the forms of publishing this type of information. The Report informs the general public about environmental situation in Slovakia and also makes comparisons to other EU member states. The following sections of the report are included: Foreword; Complex environmental monitoring and information system; Components of the environment and their protection; Major cumulative environmental pressures; Nature and landscape protection; Environmental regionalization; State of the environment - causes and consequences; Environmental risk factors; Environmental care; International co-operation; Abbreviations and SR districts.

  2. State of the Environment Report of the Slovak Republic 2006

    International Nuclear Information System (INIS)

    Klinda, J.; Lieskovska, Z.

    2008-01-01

    Environmental awareness is to be raised also through regular information on the state of environment, which forms the basis for political decisions to achieve the objectives of the National strategy for sustainable development, control and evaluation of outcomes of the national environmental policy and sectoral integration strategies. State of the Environment Report in the Slovak Republic in 2006 is only one of the forms of publishing this type of information. The Report informs the general public about environmental situation in Slovakia and also makes comparisons to other EU member states. The following sections of the report are included: Foreword; Complex environmental monitoring and information system; Components of the environment and their protection; Major cumulative environmental problems; Nature and landscape protection; Environmental regionalization; State of the environment - causes and consequences; Environmental risk factors; Environmental care; International co-operation; Abbreviations and texts to figures.

  3. French electric power balance sheet 2006

    International Nuclear Information System (INIS)

    Derdevet, Michel; Usatorre, Karine de

    2007-01-01

    The mission of RTE, the French electricity Transportation grid, a public service assignment, is to balance the electricity supply and demand in real time. This report presents RTE's technical results for the year 2006: key figures of the electricity balance sheet, RTE's public utility commitments, efficient market mechanisms and free flow of trades, lessons learnt from the power breakdown of November 4, 2006. The evolution of RTE's infrastructures and production means, the contract with Gaz de France for the improvement of Brittany's security of supply, and the results of RTE's 2006 satisfaction survey are presented in appendixes

  4. Powernext FuturesTM statistics. Jun 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the June 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for June 2006, base-load and peak-load contracts overview from January 2006 to June 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period), and market liquidity in June 2006 (average bid ask spread and availability for base-load and peak-load contracts). (J.S.)

  5. PIRLS 2006

    DEFF Research Database (Denmark)

    Mejding, Jan; Rønberg, Louise

    PIRLS 2006 er en international komparativ undersøgelse om læsekompetence i 4. klasse. Elever fra 40 lande og provinser over hele verden deltog i undersøgelsen. Det er første gang siden 1991, at danske elever på mellemtrinnet har deltaget i en international undersøgelse af læsekompetence. Dengang ...

  6. 2006 Long Range Development Plan Final Environmental ImpactReport

    Energy Technology Data Exchange (ETDEWEB)

    Philliber, Jeff

    2007-01-22

    This environmental impact report (EIR) has been prepared pursuant to the applicable provisions of the California Environmental Quality Act (CEQA) and its implementing guidelines (CEQA Guidelines), and the Amended University of California Procedures for Implementation of the California Environmental Quality Act (UC CEQA Procedures). The University of California (UC or the University) is the lead agency for this EIR, which examines the overall effects of implementation of the proposed 2006 Long Range Development Plan (LRDP; also referred to herein as the 'project' for purposes of CEQA) for Lawrence Berkeley National Laboratory (LBNL; also referred to as 'Berkeley Lab,' 'the Laboratory,' or 'the Lab' in this document). An LRDP is a land use plan that guides overall development of a site. The Lab serves as a special research campus operated by the University employees, but it is owned and financed by the federal government and as such it is distinct from the UC-owned Berkeley Campus. As a campus operated by the University of California, the Laboratory is required to prepare an EIR for an LRDP when one is prepared or updated pursuant to Public Resources Code Section 21080.09. The adoption of an LRDP does not constitute a commitment to, or final decision to implement, any specific project, construction schedule, or funding priority. Rather, the proposed 2006 LRDP describes an entire development program of approximately 980,000 gross square feet of new research and support space construction and 320,000 gross square feet of demolition of existing facilities, for a total of approximately 660,000 gross square feet of net new occupiable space for the site through 2025. Specific projects will undergo CEQA review at the time proposed to determine what, if any, additional review is necessary prior to approval. As described in Section 1.4.2, below, and in Chapter 3 of this EIR (the Project Description), the size of the project has been

  7. Powernext futures statistics - March 31, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the March 31, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for March 2006, base-load and peak-load contracts overview from October 2005 to March 2006 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity in March 2006 (average bid ask spread and availability). (J.S.)

  8. Powernext futures statistics - January 31, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the January 31, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for January 2006, base-load and peak-load contracts overview from August 2005 to January 2006 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity in January 2006 (average bid ask spread and availability). (J.S.)

  9. Developmental Course of Conversational Behaviour of Children with 22q11.2 Deletion Syndrome and Williams Syndrome

    Science.gov (United States)

    Van Den Heuvel, Ellen; Botting, Nicola; Boudewijns, Inge; Manders, Eric; Swillen, Ann; Zink, Inge

    2017-01-01

    This study investigated three conversational subskills in children with 22q11.2 deletion syndrome (22q11.2DS, n = 8, ages 7-13) and Williams syndrome (WS, n = 8, ages 6-12). The researchers re-evaluated these subskills after 18 to 24 months and compared them to those of peers with idiopathic intellectual disability (IID) and IID and comorbid…

  10. Uninformed Clinical Decisions Resulting From Lack of Adherence Assessment in Children with New Onset Epilepsy

    Science.gov (United States)

    Modi, Avani C.; Wu, Yelena P.; Guilfoyle, Shanna M.; Glauser, Tracy A.

    2012-01-01

    This study examined the relationship between non-adherence to antiepileptic drug (AED) therapy and clinical decision-making in a cohort of 112 children with newly-diagnosed epilepsy. AED adherence was monitored using electronic monitoring over the first six months of therapy. The primary outcome measure was rate of uninformed clinical decisions as defined by number of participants with AED dosage or drug changes to address continued seizures who demonstrated non-adherence prior to the seizure. Among the 52 (47%) participants who had an AED change for continued seizures, 30 (27% of the overall cohort) had imperfect medication adherence prior to their seizures. A quarter of children with new onset epilepsy had uninformed medication changes because adherence was not rigorously assessed in clinical practice. Results highlight the importance of routinely assessing medication adherence in this population. PMID:23159375

  11. 2006 nuclear power world report

    International Nuclear Information System (INIS)

    Anon.

    2007-01-01

    At the turn of 2006/2007, 437 nuclear power plants were available for energy supply, or were being commissioned, in 31 countries of the world. This is seven plants less than at the turn of 2005/2006. The aggregate gross power of the plants amounted to approx. 389.5 GWe, the aggregate net power, to 370.5 GWe. This indicates a slight decrease of gross power by some 0.15 GWe compared to the level the year before, while the available net power increased, also slightly, by approx. 0.2 GWe. The Tarapur 3 nuclear generating unit in India, a D 2 O PWR of 540 MWe gross power, was newly commissioned. In 2006, 8 nuclear power plants in Europe (4 in the United Kingdom, 2 in Bulgaria, 1 each in the Slovak Republic and in Spain) discontinued power operation for good. 29 nuclear generating units, i.e. 6 plants more than at the end of 2005, were under construction in late 2006 in 9 countries with an aggregate gross power of approx. 25.5 GWe. Worldwide, some 40 new nuclear power plants are in the concrete project design, planning, and licensing phases; in some of these cases, contracts have already been signed. Net electricity generation in nuclear power plants worldwide in 2006 achieved another top ranking level of approx. 2,660 billion kWh (2005: approx. 2,750 billion kWh). Since the first generation of electricity in a nuclear power plant in the EBR-1 fast breeder (USA) on December 20, 1951, cumulated gross production has reached approx. 56,875 billion kWh, and operating experience has grown to some 12,399 reactor years. (orig.)

  12. Probabilistic Decision Based Block Partitioning for Future Video Coding

    KAUST Repository

    Wang, Zhao

    2017-11-29

    In the latest Joint Video Exploration Team development, the quadtree plus binary tree (QTBT) block partitioning structure has been proposed for future video coding. Compared to the traditional quadtree structure of High Efficiency Video Coding (HEVC) standard, QTBT provides more flexible patterns for splitting the blocks, which results in dramatically increased combinations of block partitions and high computational complexity. In view of this, a confidence interval based early termination (CIET) scheme is proposed for QTBT to identify the unnecessary partition modes in the sense of rate-distortion (RD) optimization. In particular, a RD model is established to predict the RD cost of each partition pattern without the full encoding process. Subsequently, the mode decision problem is casted into a probabilistic framework to select the final partition based on the confidence interval decision strategy. Experimental results show that the proposed CIET algorithm can speed up QTBT block partitioning structure by reducing 54.7% encoding time with only 1.12% increase in terms of bit rate. Moreover, the proposed scheme performs consistently well for the high resolution sequences, of which the video coding efficiency is crucial in real applications.

  13. 2006 statistical data of the French gas industry

    International Nuclear Information System (INIS)

    2007-12-01

    This document makes a synthesis of the 2006 results of the annual inquiry about the French natural gas industry: 1 - organization of the French gas market (production, transport, methane terminals, storage facilities, distribution, commercialization, main steps of the opening of the gas market in France); 2 - the 2006 gas year (consumption, imports, production, stockpiles); 3 - results of the 2006 inquiry: infrastructures (storage capacities, pipelines and distribution network), production (evolution of natural gas and industrial gases production, uses), transport (inputs and outputs, geographical origin of inputs in 2005 and 2006, raw imports evolution since 1973), storage (evolution of stockpiles variation), natural gas supplies (sectoral uses), supplies by region and by sector in 2006, consumption by sector; 4 - power generation by gas cogeneration in 2005 (plants characteristics, classification, cogeneration status (in TWh), regional distribution of plants); 5 - 2006 monthly changes (inputs, net imports, consumption and useful stockpile, consumption and net imports); 6 - international comparisons (gas share in the overall energy consumption, consumption per user, evolution of main sectors of consumption in some European countries since 1973); 7 - appendixes: French transportation network, main gas roads in Europe, European gas fluxes, 2006 energy status, gas statuses during the past three years. (J.S.)

  14. Séminaire de l'enseignement technique : Forum AutoCAD 2006 et AutoCAD Mechanical 2006

    - French version only

    CERN Multimedia

    Davide Vitè

    2005-01-01

    Jeudi 17 novembre 2005 de 14:30 à 16:30 - Training Centre Auditorium, Bât 593 Forum AutoCAD 2006 et AutoCAD Mechanical 2006 CADSCHOOL, CH-1207 GENEVE, Suisse Ce nouveau séminaire de l'Enseignement technique, organisé en forme de forum et en collaboration avec TS-MME et notre entreprise partenaire en formation, sera consacré à la présentation de la nouvelle version d'AutoCAD, AutoCAD 2006 et AutoCAD Mechanical 2006, disponible au CERN. Au programme : Présentation d'AutoCAD Mechanical 2006 Améliorations par rapport à AutoCAD Mechanical 6 Power Pack Questions - Réponses Langue: Français. Séminaire libre, sans inscription. Organisateurs: Manfred Mayer / TS-MME / 74499 ; Davide Vitè / HR-PMD / 75141 Pour plus d'information, veuillez SVP visiter les pages des Séminaires de l'Enseignement Technique à l'adresse http://www.cern.ch/TechnicalTraining/special/TTseminars.asp . ENSEIGNEMENT TECHNIQUE TECHNICAL TRAINING technical.training@cern.ch

  15. Official holidays in 2006 and end-of-year closure 2006/2007

    CERN Multimedia

    2006-01-01

    (Application of Articles R II 4.33 and R II 4.34 of the Staff Regulations) Official holidays in 2006 (in addition to the end-of-year holidays) : Friday, 14th April (Good Friday) Monday, 17th April (Easter Monday) Monday,1st May Thursday, 25th May (Ascension Day) Monday, 5th June (Whit Monday) Thursday, 7th September ('Jeûne genevois') Annual closure of the site of the Organization during the Christmas holidays and day of special leave granted by the Director-General : The Laboratory will be closed from Saturday, 23rd December 2006 to Sunday, 7th January 2007 inclusive (without deduction of annual leave). The first working day in the New Year will be Monday, 8th January 2007. Human Resources Department Tel. 74128

  16. Installation and testing of the 112 boards for the front-end electronics.

    CERN Multimedia

    2006-01-01

    Installation and testing of the 112 boards for the front-end electronics. 28 boards are interconnected to a TPC type Readout Controller Unit trought the horizontal bus strips. The blue tubes are for the circulating cooling water.

  17. Annual report 2006

    International Nuclear Information System (INIS)

    Anon

    2007-04-01

    In this Annual report the operating of the Slovak Environmental Agency in 2006 is reported. The structure of the Agency, mission, personnel structure, financing, monitoring of the environment, international cooperation and coordination of research programmes are reviewed

  18. Accelerator/Experiment operations - FY 2006

    Energy Technology Data Exchange (ETDEWEB)

    Brice, S.; Conrad, J.; Denisov, D.; Ginther, G.; Holmes, S.; James, C.; Lee, W.; Louis, W.; Moore, C.; Plunkett, R.; Raja, R.; /Fermilab

    2006-10-01

    This Technical Memorandum (TM) summarizes the Fermilab accelerator and experiment operations for FY 2006. It is one of a series of annual publications intended to gather information in one place. In this case, the information concerns the FY 2006 Run II at the Tevatron Collider, the MiniBooNE experiments running in the Booster Neutrino Beam in neutrino and antineutrino modes, MINOS using the Main Injector Neutrino Beam (NuMI), and SY 120 activities.

  19. Mother-Child Interaction as a Window to a Unique Social Phenotype in 22q11.2 Deletion Syndrome and in Williams Syndrome

    Science.gov (United States)

    Weisman, Omri; Feldman, Ruth; Burg-Malki, Merav; Keren, Miri; Geva, Ronny; Diesendruck, Gil; Gothelf, Doron

    2015-01-01

    Mother-child interactions in 22q11.2 Deletion syndrome (22q11.2DS) and Williams syndrome (WS) were coded for maternal sensitivity/intrusiveness, child's expression of affect, levels of engagement, and dyadic reciprocity. WS children were found to express more positive emotions towards their mothers compared to 22q11.2DS children and those with…

  20. 22q11.2 deletion syndrome: behaviour problems of children and adolescents and parental stress.

    Science.gov (United States)

    Briegel, W; Schneider, M; Schwab, K Otfried

    2008-11-01

    22q11.2 deletion syndrome can be associated with a variety of somatic symptoms, developmental delays and psychiatric disorders. At present, there is little information on behaviour problems, parental stress and possible relations between these factors. Therefore, this study investigates behaviour problems of children and adolescents with 22q11.2DS, and their primary caregivers' stress. Parents of 4-17 year old subjects known to the German 22q11.2 deletion syndrome foundation were anonymously asked to fill out several questionnaires, e.g. the Child Behavior Checklist 4-18 (CBCL/4-18). The primary caregivers of 77/126 children [43 males, 34 females, mean age: 8;0 (4;0-16;11) years] sent back filled-out questionnaires. Forty-six of 76 subjects were rated as clinical on at least one of the CBCL-scales. Males had significantly higher scores on the total problems scale and the internalizing problems scale than females. The patients' age correlated with several CBCL-scales. Eleven of 49 subjects were suspicious of an autism spectrum disorder. Compared with the general population, but not with other parents of mentally and/or physically handicapped children, the primary caregivers experienced higher levels of stress, but showed normal life satisfaction. In spite of high rates of clinical behaviour problems among children and adolescents with 22q11.2DS and despite increased parental stress, most primary caregivers seem to have effective coping strategies, e.g. partnership support, to sustain normal levels of life satisfaction.

  1. Parental explicit heuristics in decision-making for children with life-threatening illnesses.

    Science.gov (United States)

    Renjilian, Chris B; Womer, James W; Carroll, Karen W; Kang, Tammy I; Feudtner, Chris

    2013-02-01

    To identify and illustrate common explicit heuristics (decision-making aids or shortcuts expressed verbally as terse rules of thumb, aphorisms, maxims, or mantras and intended to convey a compelling truth or guiding principle) used by parents of children with life-threatening illnesses when confronting and making medical decisions. Prospective cross-sectional observational study of 69 parents of 46 children who participated in the Decision-making in Pediatric Palliative Care Study between 2006 and 2008 at the Children's Hospital of Philadelphia. Parents were guided individually through a semistructured in-depth interview about their experiences and thoughts regarding making medical decisions on behalf of their ill children, and the transcribed interviews were qualitatively analyzed. All parents in our study employed explicit heuristics in interviews about decision-making for their children, with the number of identified explicit heuristics used by an individual parent ranging from tens to hundreds. The heuristics served 5 general functions: (1) to depict or facilitate understanding of a complex situation; (2) to clarify, organize, and focus pertinent information and values; (3) to serve as a decision-making compass; (4) to communicate with others about a complex topic; and (5) to justify a choice. Explicit heuristics played an important role in decision-making and communication about decision-making in our population of parents. Recognizing explicit heuristics in parent interactions and understanding their content and functions can aid clinicians in their efforts to partner with parents in the decision-making process.

  2. INIS Progress and Activity Report 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-05-15

    Highlights of INIS Activities 2006: INIS, the International Nuclear Information System, is an established nuclear information resource operated by the IAEA on behalf of its Members. Its primary mission is to foster an open information exchange for the scientific benefit of its Members. In 2006, four new members joined INIS: the Central African Republic, Namibia, Luxembourg, and the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC). This brings the total number of INIS members to 140. 2006 saw a significant increase in the support provided to INIS Member States through the IAEA Technical Co-operation Department. INIS Database: With the successful completion of volume 37 of the INIS Bibliographic Database, a total of 122 412 records were added in 2006, which is the best result in INIS history and corresponds to a 100% increase compared to 1999 when INIS started the Computer-Assistance-Indexing (CAI) project. This very impressive result was achieved with the competent work of the INIS team and in cooperation with Member States. The total number of records in the INIS Database has reached 2 778 427. INIS NCL Collection: In 2006, the electronic full-text of 14 610 NCL documents were processed and added to the INIS NCL collection and a total of 47 NCL CDs were produced and distributed to designated Document Delivery Centres in INIS Member States.

  3. INIS Progress and Activity Report 2006

    International Nuclear Information System (INIS)

    2007-05-01

    Highlights of INIS Activities 2006: INIS, the International Nuclear Information System, is an established nuclear information resource operated by the IAEA on behalf of its Members. Its primary mission is to foster an open information exchange for the scientific benefit of its Members. In 2006, four new members joined INIS: the Central African Republic, Namibia, Luxembourg, and the Brazilian-Argentine Agency for Accounting and Control of Nuclear Materials (ABACC). This brings the total number of INIS members to 140. 2006 saw a significant increase in the support provided to INIS Member States through the IAEA Technical Co-operation Department. INIS Database: With the successful completion of volume 37 of the INIS Bibliographic Database, a total of 122 412 records were added in 2006, which is the best result in INIS history and corresponds to a 100% increase compared to 1999 when INIS started the Computer-Assistance-Indexing (CAI) project. This very impressive result was achieved with the competent work of the INIS team and in cooperation with Member States. The total number of records in the INIS Database has reached 2 778 427. INIS NCL Collection: In 2006, the electronic full-text of 14 610 NCL documents were processed and added to the INIS NCL collection and a total of 47 NCL CDs were produced and distributed to designated Document Delivery Centres in INIS Member States

  4. In vitro corrosion of Mg–1.21Li–1.12Ca–1Y alloy

    Directory of Open Access Journals (Sweden)

    Rongchang Zeng

    2014-10-01

    Full Text Available The influence of the microstructure on mechanical properties and corrosion behavior of the Mg–1.21Li–1.12Ca–1Y alloy was investigated using OM, SEM, XRD, EPMA, EDS, tensile tests and corrosion measurements. The results demonstrated that the microstructure of the Mg–1.21Li–1.12Ca–1Y alloy was characterized by α-Mg substrate and intermetallic compounds Mg2Ca and Mg24Y5. Most of the fine Mg2Ca particles for the as-cast alloy were distributed along the grain boundaries, while for the as-extruded along the extrusion direction. The Mg24Y5 particles with a larger size than the Mg2Ca particles were positioned inside the grains. The mechanical properties of Mg–1.21Li–1.12Ca–1Y alloy were improved by the grain refinement and dispersion strengthening. Corrosion pits initiated at the α-Mg matrix neighboring the Mg2Ca particles and subsequently the alloy exhibited general corrosion and filiform corrosion as the corrosion product layer of Mg(OH2 and MgCO3 became compact and thick.

  5. 112-Gbit/s × 4-lane duobinary-4-PAM for 400GBase

    DEFF Research Database (Denmark)

    Suhr, Lau Frejstrup; Vegas Olmos, Juan José; Mao, B.

    2014-01-01

    Novel duobinary-4-PAM signaling is experimentally demonstrated to support a 4-lane low-latency 400GbE client side solution. Direct detection of 112 Gbps transmission over a 5 km single wavelength and polarization fiber link is achieved....

  6. Decision making technical support study for the US Army's Chemical Stockpile Disposal Program

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, D.L.; Dobson, J.E.

    1990-08-01

    This report examines the adequacy of current command and control systems designed to make timely decisions that would enable sufficient warning and protective response to an accident at the Edgewood area of Aberdeen Proving Ground (APG), Maryland, and at Pine Bluff Arsenal (PBA), Arkansas. Institutional procedures designed to facilitate rapid accident assessment, characterization, warning, notification, and response after the onset of an emergency and computer-assisted decision-making aids designed to provide salient information to on- and-off-post emergency responders are examined. The character of emergency decision making at APG and PBA, as well as potential needs for improvements to decision-making practices, procedures, and automated decision-support systems (ADSSs), are described and recommendations are offered to guide equipment acquisition and improve on- and off-post command and control relationships. We recommend that (1) a continued effort be made to integrate on- and off-post command control, and decision-making procedures to permit rapid decision making; (2) the pathways for alert and notification among on- and off-post officials be improved and that responsibilities and chain of command among off-post agencies be clarified; (3) greater attention be given to organizational and social context factors that affect the adequacy of response and the likelihood that decision-making systems will work as intended; and (4) faster improvements be made to on-post ADSSs being developed at APG and PBA, which hold considerable promise for depicting vast amounts of information. Phased development and procurement of computer-assisted decision-making tools should be undertaken to balance immediate needs against available resources and to ensure flexibility, equity among sites, and compatibility among on- and off-post systems. 112 refs., 6 tabs.

  7. Defining the Effect of the 16p11.2 Duplication on Cognition, Behavior, and Medical Comorbidities

    DEFF Research Database (Denmark)

    D'Angelo, Debra; Lebon, Sébastien; Chen, Qixuan

    2016-01-01

    Importance: The 16p11.2 BP4-BP5 duplication is the copy number variant most frequently associated with autism spectrum disorder (ASD), schizophrenia, and comorbidities such as decreased body mass index (BMI). Objectives: To characterize the effects of the 16p11.2 duplication on cognitive...... subgroups not observed with the deletion. These results suggest that additional genetic and familial factors contribute to this variability. Additional studies will be necessary to characterize the predictors of cognitive deficits....

  8. Comparing the Broad Socio-Cognitive Profile of Youth with Williams Syndrome and 22Q11.2 Deletion Syndrome

    Science.gov (United States)

    Weisman, O.; Feldman, R.; Burg-Malki, M.; Keren, M.; Geva, R.; Diesendruck, G.; Gothelf, D.

    2017-01-01

    Background: Numerous studies have assessed the socio-cognitive profile in Williams syndrome (WS) and, independently, in 22q11.2 deletion syndrome (22q11.2DS). Yet, a cross-syndrome comparison of these abilities between individuals with these two syndromes with known social deficits has not been conducted. Methods: Eighty-two children participated…

  9. Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology

    Science.gov (United States)

    Sanders, Ashley F.; Hobbs, Diana A.; Stephenson, David D.; Laird, Robert D.; Beaton, Elliott A.

    2017-01-01

    Stress and anxiety have a negative impact on working memory systems by competing for executive resources and attention. Broad memory deficits, anxiety, and elevated stress have been reported in individuals with chromosome 22q11.2 deletion syndrome (22q11.2DS). We investigated anxiety and physiological stress reactivity in relation to visuospatial…

  10. Bioactivation mechanism of the cytotoxic and nephrotoxic S-conjugate S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine

    International Nuclear Information System (INIS)

    Dekant, W.; Lash, L.H.; Anders, M.W.

    1987-01-01

    The bioactivation of S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine (CTFC) was studied with purified bovine kidney cysteine conjugate β-lyase and with N-dodecylpyridoxal bromide in cetyltrimethylammonium bromide micelles as a pyridoxal model system. The β-lyase and the pyridoxal model system converted CTFC to chlorofluoroacetic acid and inorganic fluoride, which were identified by 19 F NMR spectrometry. 2-Chloro-1,1,2-trifluoroethanethiol and chlorofluorothionoacetyl fluoride were formed as metabolites of CTFC and were trapped with benzyl bromide and diethylamine, respectively, to yield benzyl 2-chloro-1,1,2-trifluoroethyl sulfide and N,N-diethyl chlorofluorothioacetamide, which were identified by gas chromatography/mass spectrometry. The bioactivation mechanism of CTFC therefore involves the initial formation of the unstable thiol 2-chloro-1,1,2-trifluoroethanethiol, which loses hydrogen fluoride to form the acylating agent chlorofluorothionoacetyl fluoride; hydrolysis of the thionoacyl fluoride affords the stable, terminal metabolites chlorofluoroacetic acid and inorganic fluoride. The intermediate acylating agent and chlorofluoroacetic acid may contribute to the cytotoxic effects of CTFC

  11. 34 CFR 200.6 - Inclusion of all students.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Inclusion of all students. 200.6 Section 200.6... Basic Programs Operated by Local Educational Agencies Standards and Assessments § 200.6 Inclusion of all...— (A) For each student with a disability, as defined under section 602(3) of the IDEA, appropriate...

  12. GeNF - Experimental report 2006

    International Nuclear Information System (INIS)

    Pranzas, P.K.; Schreyer, A.; Willumeit, R.

    2007-01-01

    At the Geesthacht Neutron Facility GeNF about 212 experiments were performed in 2006 by GKSS and by or for external users, partners or contractors. In most cases the measurements were performed and analysed in cooperation by the guests and by the GKSS staff or by the permanent external user group staff. The activities, which are based on a proposal procedure and on the in house R and D program, are reported in 71 contributions in the present annual experimental report for the year 2006. The contributions may contain one or also several combined experiments. During 2006 the GKSS research reactor FRG-1 achieved an operation time of 197 days at the full 5 MW reactor power providing a neutron flux of ca. 1.4 x 10 14 thermal neutrons/cm 2 s. The cold neutron source was available during the complete operation time. The focus of the in house R and D work at GeNF instruments was the characterisation of nanostructures in engineering materials, the analysis of stresses and textures in welds and technical structures at ARES-2, TEX-2, DCD and SANS-2, the structural investigation of hydrogen containing substances such as polymers, colloids and biological macromolecules at SANS-1 as well as the characterisation of magnetic thin films at PNR, NeRo, POLDI and ROeDI. The thoroughly upgraded residual stress diffractomer ARES-2 went in full operation in spring 2006 as well as the new neutron tomography device at GENRA-3. The installation of modern experiment control hardware and software based on LabView was completed on all designated instruments. In the appendices I and II the experimental reports of REFSANS at FRM II are attached as well as of the GKSS outstation HARWI-II at DESY. Both instruments started full operation in 2006. (orig.)

  13. GeNF - Experimental report 2006

    Energy Technology Data Exchange (ETDEWEB)

    Pranzas, P K; Schreyer, A; Willumeit, R [GKSS-Forschungszentrum Geesthacht GmbH (Germany). Inst. of Materials Research

    2007-07-01

    At the Geesthacht Neutron Facility GeNF about 212 experiments were performed in 2006 by GKSS and by or for external users, partners or contractors. In most cases the measurements were performed and analysed in cooperation by the guests and by the GKSS staff or by the permanent external user group staff. The activities, which are based on a proposal procedure and on the in house R and D program, are reported in 71 contributions in the present annual experimental report for the year 2006. The contributions may contain one or also several combined experiments. During 2006 the GKSS research reactor FRG-1 achieved an operation time of 197 days at the full 5 MW reactor power providing a neutron flux of ca. 1.4 x 10{sup 14} thermal neutrons/cm{sup 2}s. The cold neutron source was available during the complete operation time. The focus of the in house R and D work at GeNF instruments was the characterisation of nanostructures in engineering materials, the analysis of stresses and textures in welds and technical structures at ARES-2, TEX-2, DCD and SANS-2, the structural investigation of hydrogen containing substances such as polymers, colloids and biological macromolecules at SANS-1 as well as the characterisation of magnetic thin films at PNR, NeRo, POLDI and ROeDI. The thoroughly upgraded residual stress diffractomer ARES-2 went in full operation in spring 2006 as well as the new neutron tomography device at GENRA-3. The installation of modern experiment control hardware and software based on LabView was completed on all designated instruments. In the appendices I and II the experimental reports of REFSANS at FRM II are attached as well as of the GKSS outstation HARWI-II at DESY. Both instruments started full operation in 2006. (orig.)

  14. Tank characterization report for single-shell tank 241-U-112

    International Nuclear Information System (INIS)

    Field, J.G.

    1998-01-01

    A major function of the Tank Waste Remediation System (TWRS) is to characterize waste in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis and other available information about a tank are compiled and maintained in a tank characterization report (TCR). This report and its appendixes serve as the TCR for single-shell tank 241-U-112. The objectives of this report are (1) to use characterization data in response to technical issues associated with tank 241-U-112 waste, and (2) to provide a standard characterization of this waste in terms of a best-basis inventory estimate. Section 2.0 summarizes the response to technical issues, Section 3.0 shows the best-basis inventory estimate, Section 4.0 makes recommendations about the safety status of the tank and additional sampling needs. The appendixes contain supporting data and information. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1997), Milestone M-44-15b, change request M-44-97-03 to issue characterization deliverables consistent with the Waste Information Requirements Document developed for 1998

  15. Tank characterization report for single-shell tank 241-T-112

    International Nuclear Information System (INIS)

    McCain, D.J.

    1998-01-01

    A major function of the Tank Waste Remediation System (TWRS) is to characterize waste in support of waste management and disposal activities at the Hanford Site. Analytical data from sampling and analysis and other available information about a tank are compiled and maintained in a tank characterization report (TCR). This report and its appendices serve as the TCR for single-shell tank 241-T-112. The objectives of this report are (1) to use characterization data in response to technical issues associated with tank 241-T-112 waste and (2) to provide a standard characterization of this waste in terms of a best-basis inventory estimate. Section 2.0 summarizes the response to technical issues, Section 3.0 shows the best-basis inventory estimate, Section 4.0 makes recommendations about the safety status of the tank and additional sampling needs. The appendices contain supporting data and information. This report supports the requirements of the Hanford Federal Facility Agreement and Consent Order (Ecology et al. 1997), Milestone M-44-15b, change request M-44-97-03, to ''issue characterization deliverables consistent with the Waste Information Requirements Documents developed for 1998.''

  16. Association of COMT and PRODH gene variants with intelligence quotient (IQ) and executive functions in 22q11.2DS subjects.

    Science.gov (United States)

    Carmel, Miri; Zarchi, Omer; Michaelovsky, Elena; Frisch, Amos; Patya, Miriam; Green, Tamar; Gothelf, Doron; Weizman, Abraham

    2014-09-01

    The 22q11.2 deletion syndrome (22q11.2DS) carries the highest genetic risk factor for the development of schizophrenia. We investigated the association of genetic variants in two schizophrenia candidate genes with executive function (EF) and IQ in 22q11.2DS individuals. Ninety two individuals with 22q11.2 deletion were studied for the genetic association between COMT and PRODH variants and EF and IQ. Subjects were divided into children (under 12 years old), adolescents (between 12 and 18 years old) and adults (older than 18 years), and genotyped for the COMT Val158Met (rs4680) and PRODH Arg185Trp (rs4819756) polymorphisms. The participants underwent psychiatric evaluation and EF assessment. Our main finding is a significant influence of the COMT Val158Met polymorphism on both IQ and EF performance. Specifically, 22q11.2DS subjects with Met allele displayed higher IQ scores in all age groups compared to Val carriers, reaching significance in both adolescents and adults. The Met allele carriers performed better than Val carriers in EF tasks, being statistically significant in the adult group. PRODH Arg185Trp variant did not affect IQ or EF in our 22q11.2DS cohort. In conclusion, functional COMT variant, but not PRODH, affects IQ and EF in 22q11.2DS subjects during neurodevelopment with a maximal effect at adulthood. Future studies should monitor the cognitive performance of the same individuals from childhood to old age. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. CERN Technical Training 2006: Software and System Technologies Curriculum - Scheduled

    CERN Multimedia

    2006-01-01

    Course Sessions (October 2006-March 2007) The Software and System Technologies Curriculum of the CERN Technical Training Programme offers comprehensive training in C++, Java, Perl, Python, XML, OO programming, JCOP/PVSS, database design and Oracle. In the PERL, C++, OO and Java course series there are some places available on the following course sessions, currently scheduled until March 2007: Object-Oriented Analysis and Design using UML: 17-19 October 2006 (3 days) JAVA 2 Enterprise Edition - Part 1: Web Applications: 19-20 October 2006 (2 days) JAVA - Level 1: 30 October -1 November 2006 (3 days) PERL 5 - Advanced Aspects: 2 November 2006 (1 day) C++ Programming Part 1 - Introduction to Object-Oriented Design and Programming: 14-16 November 2006 (3 days) JAVA - Level 2: 4-7 December 2006 (4 days) C++ Programming Part 2 - Advanced C++ and its Traps and Pitfalls: 12-15 December 2006 (4 days) JAVA 2 Enterprise Edition - Part 2: Enterprise JavaBeans: 18-20 December 2006 (3 days) C++ for Particle Physicists:...

  18. Annual report and balance 2006; Memoria y balance 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    A summary of the research, development, services and production activities of the National Atomic Energy Commission (CNEA) of Argentina is given as well as details of management resources together with the evolution of the budget. The activities of the CNEA related companies during 2006 are also outlined. A special mention is made of the activities of the three CNEA educational and training institutes.

  19. 2006, a year of strong headwind; 2006 war ein Jahr mit viel Gegenwind

    Energy Technology Data Exchange (ETDEWEB)

    Schuermann, H.J. [Handelsblatt, Duesseldorf (Germany)

    2006-12-15

    2006 was a 'hot' year: The image of the power industry suffered as a result of monopolistic practices and excessive profits. Politicians and consumers also state that investments in the development of new capacities and in an environment-friendly infrastructure are kept at allow level in order to maintain a situation of relative supply shortage, which is favourable to the high price level. There are calls for more rigid control and regulation of the energy market. Even more than former years, 2006 showed that the energy problem is an international challenge. The review of the year therefore focuses on the internationalisation of the energy market. (orig.)

  20. Biotechnology Industry, 2006

    Science.gov (United States)

    2006-01-01

    for commercial or other purposes. Because it is a process resting on the understanding of genetics, proteomics , and life science, biotechnology has...Luhnow & Samor, 2006). Novel biotechnologies could bring down the costs of making ethanol. Iogen Corporation has genetically modified a fungus to

  1. Inequality in the distribution of expense allocated to the main energy fuels for Mexican households. 1968-2006

    Energy Technology Data Exchange (ETDEWEB)

    Rosas-Flores, Jorge Alberto [Division de Estudios de Posgrado, Facultad de Ingenieria, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria Coyoacan 04510, DF (Mexico); Morillon Galvez, David; Fernandez Zayas, Jose Luis [Instituto de Ingenieria, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Coyoacan 04510, DF (Mexico)

    2010-09-15

    Energy is a decisive and essential factor to provide quality of life, technological development related to its use, and an economic development overview of a given country. This essay presents the expense distribution allocated to the main fuel sources used at Mexican households. The essay herein was carried out for the 1968-2006 period. The main purpose of this essay is to determine the expense allocation of the main energy fuels (electricity, gas, firewood, kerosene, gasoline).The methodology used in this essay is based on the Lorenz curves and Gini coefficient. (author)

  2. 19 CFR 12.112 - Notice of arrival of pesticides and devices.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Notice of arrival of pesticides and devices. 12...; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Pesticides and Devices § 12.112 Notice of arrival of pesticides and devices. (a) General. An importer desiring to import pesticides or devices into the...

  3. STS-112 final main engine is installed after welding/polishing process

    Science.gov (United States)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- The last engine is installed in orbiter Atlantis after a welding and polishing process was undertaken on flow liners where cracks were detected. All engines were removed for inspection of flow liners. Atlantis will next fly on mission STS-112, scheduled for launch no earlier than Oct. 2.

  4. Forest science in the South - 2006

    Science.gov (United States)

    Southern Research Station USDA Forest Service

    2007-01-01

    Welcome to the Southern Research Station's 2006 Forest Science in the South. Our summary highlights key accomplishments and activities from this past fiscal year, October 1, 2005, through September 30, 2006.This was a dynamic year for the Station! We recently realigned our 28 research work units (RWUs) into 15 RWUs grouped under five science areas –...

  5. Schostakowitsch: Sinfonie Nr. 12 op. 112 (Das Jahr 1917) / Hans-Christian Dadelsen

    Index Scriptorium Estoniae

    Dadelsen, Hans-Christian

    1991-01-01

    Uuest heliplaadist "Schostakowitsch: Sinfonie Nr. 12 op. 112 (Das Jahr 1917). Hamlet-Suite op. 32a. Das goldene Zeitalter [The Age of Gold] (Suite) op. 22a. Göteborger Symphoniker, Neeme Järvi". DG CD 431 688-2 (WD:77'21") DDD

  6. VUEZ. Annual report 2006

    International Nuclear Information System (INIS)

    2007-01-01

    A brief account of activities carried out by the Vyskumny ustav energetickych zariadeni, a.s. (VUEZ) in 2006 is presented. These activities are reported under the headings: (1) Introductory address by the Chairman of the Board of Directors; (2) Company profile; (3) Organisational structure; (4) Portfolio of products and services in 2006; (5) Quality management system; (6) Human resources; (7) Financial statements and auditor's report; (8) Auditor's certificate; (9) Basic and contact data. The year 2006 was a year of changes in the Slovak energy sector what, in a certain degree, became evident also in the related sphere of supplies. In the course of the year, Slovenske elektrarne a.s. Company was divided into two entities and its proprietary structure was changed. At the same time, the number of capital investment projects was reduced and the related procedure of procurement was changed. VUEZ, as a supplier to the energy sector, had to promptly respond to the changes. That was why in the first half of 2006, the organisational structure of VUEZ was modified. In the course of the year, also the structure of customers on the domestic market was partly changed. To stable partners such as Slovenske elektrarne (and its successors after the company splitting), another important partner was added - Vodohospodarska vystavba s.p. Bratislava. As to Slovenske elektrarne, our supplies were oriented mainly on nuclear reactor units in the Jaslovske Bohunice and Mochovce NPPs. At the end of the year, a joint convention was agreed and concluded on application of the results of the joint research at third parties. In the preparation for the decommissioning of the Jaslovske Bohunice V1 NPP, VUEZ continued its participation in on-going projects of an international consortium of companies. Similarly important were the customers such as CEZ a.s., Czech Republic (in particular its Dukovany NPP), and the Paks NPP (Hungary)

  7. Closing Rocky Flats by 2006

    International Nuclear Information System (INIS)

    Tuor, N. R.; Schubert, A. L.

    2002-01-01

    Safely accelerating the closure of Rocky Flats to 2006 is a goal shared by many: the State of Colorado, the communities surrounding the site, the U.S. Congress, the Department of Energy, Kaiser-Hill and its team of subcontractors, the site's employees, and taxpayers across the country. On June 30, 2000, Kaiser-Hill (KH) submitted to the Department of Energy (DOE), KH's plan to achieve closure of Rocky Flats by December 15, 2006, for a remaining cost of $3.96 billion (February 1, 2000, to December 15, 2006). The Closure Project Baseline (CPB) is the detailed project plan for accomplishing this ambitious closure goal. This paper will provide a status report on the progress being made toward the closure goal. This paper will: provide a summary of the closure contract completion criteria; give the current cost and schedule variance of the project and the status of key activities; detail important accomplishments of the past year; and discuss the challenges ahead

  8. Annual Statistical Supplement, 2006

    Data.gov (United States)

    Social Security Administration — The Annual Statistical Supplement, 2006 includes the most comprehensive data available on the Social Security and Supplemental Security Income programs. More than...

  9. The influence of discrete emotions on judgement and decision-making: a meta-analytic review.

    Science.gov (United States)

    Angie, Amanda D; Connelly, Shane; Waples, Ethan P; Kligyte, Vykinta

    2011-12-01

    During the past three decades, researchers interested in emotions and cognition have attempted to understand the relationship that affect and emotions have with cognitive outcomes such as judgement and decision-making. Recent research has revealed the importance of examining more discrete emotions, showing that same-valence emotions (e.g., anger and fear) differentially impact judgement and decision-making outcomes. Narrative reviews of the literature (Lerner & Tiedens, 2006 ; Pham, 2007 ) have identified some under-researched topics, but provide a limited synthesis of findings. The purpose of this study was to review the research examining the influence of discrete emotions on judgement and decision-making outcomes and provide an assessment of the observed effects using a meta-analytic approach. Results, overall, show that discrete emotions have moderate to large effects on judgement and decision-making outcomes. However, moderator analyses revealed differential effects for study-design characteristics and emotion-manipulation characteristics by emotion type. Implications are discussed.

  10. Two phloem nitrate transporters, NRT1.11 and NRT1.12, are important for redistributing xylem-borne nitrate to enhance plant growth.

    Science.gov (United States)

    Hsu, Po-Kai; Tsay, Yi-Fang

    2013-10-01

    This study of the Arabidopsis (Arabidopsis thaliana) nitrate transporters NRT1.11 and NRT1.12 reveals how the interplay between xylem and phloem transport of nitrate ensures optimal nitrate distribution in leaves for plant growth. Functional analysis in Xenopus laevis oocytes showed that both NRT1.11 and NRT1.12 are low-affinity nitrate transporters. Quantitative reverse transcription-polymerase chain reaction and immunoblot analysis showed higher expression of these two genes in larger expanded leaves. Green fluorescent protein and β-glucuronidase reporter analyses indicated that NRT1.11 and NRT1.12 are plasma membrane transporters expressed in the companion cells of the major vein. In nrt1.11 nrt1.12 double mutants, more root-fed (15)NO3(-) was translocated to mature and larger expanded leaves but less to the youngest tissues, suggesting that NRT1.11 and NRT1.12 are required for transferring root-derived nitrate into phloem in the major veins of mature and larger expanded leaves for redistributing to the youngest tissues. Distinct from the wild type, nrt1.11 nrt1.12 double mutants show no increase of plant growth at high nitrate supply. These data suggested that NRT1.11 and NRT1.12 are involved in xylem-to-phloem transfer for redistributing nitrate into developing leaves, and such nitrate redistribution is a critical step for optimal plant growth enhanced by increasing external nitrate.

  11. E-learning Nordic 2006

    DEFF Research Database (Denmark)

    Pedersen, Sanya Gertsen

    2006-01-01

    E-learning Nordic 2006 er den første fællesnordiske undersøgelse, som specifikt fokuserer på effekten af it i uddannelsessektoren. Studiet er gennemført i Finland, Sverige, Norge og Danmark og mere end 8000 personer (elever, lærere, forældre og skoleledere i grundskoler og på de gymnasiale...... ungdomsuddannelser) har deltaget. Dette studie giver en række svar på centrale spørgsmål såsom: Hvad har vi fået ud af satsningen på it i uddannelsessektoren indtil nu? Og hvilke udfordringer inden for uddannelsessektoren står de nordiske lande foran i en globaliseret verden? E-learning Nordic 2006 er designet og...

  12. Risk of Psychiatric Disorders Among Individuals With the 22q11.2 Deletion or Duplication

    DEFF Research Database (Denmark)

    Hoeffding, Louise K; Trabjerg, Betina B; Olsen, Line

    2017-01-01

    ) age at diagnosis of any psychiatric disorder was 12.5 (8.3) years for individuals with deletions and 6.1 (0.9) years for duplication carriers. A parental diagnosis of schizophrenia-but not of other psychiatric diagnoses-was associated with a 22q11.2 deletion, and parental psychiatric diagnoses other.......2 deletion or duplicationwas performed. A total of 3 768 943 individuals born in Denmark from 1955 to 2012 were followed up during the study period (total follow-up, 57.1 million person-years). Indicators of 22q11.2 deletion or duplication and cumulative incidenceswere estimated using a nested case...

  13. Women's autonomy in household decision-making: a demographic study in Nepal.

    Science.gov (United States)

    Acharya, Dev R; Bell, Jacqueline S; Simkhada, Padam; van Teijlingen, Edwin R; Regmi, Pramod R

    2010-07-15

    How socio-demographic factors influence women's autonomy in decision making on health care including purchasing goods and visiting family and relatives are very poorly studied in Nepal. This study aims to explore the links between women's household position and their autonomy in decision making. We used Nepal Demographic Health Survey (NDHS) 2006, which provided data on ever married women aged 15-49 years (n = 8257). The data consists of women's four types of household decision making; own health care, making major household purchases, making purchase for daily household needs and visits to her family or relatives. A number of socio-demographic variables were used in multivariable logistic regression to examine the relationship of these variables to all four types of decision making. Women's autonomy in decision making is positively associated with their age, employment and number of living children. Women from rural area and Terai region have less autonomy in decision making in all four types of outcome measure. There is a mixed variation in women's autonomy in the development region across all outcome measures. Western women are more likely to make decision in own health care (1.2-1.6), while they are less likely to purchase daily household needs (0.6-0.9). Women's increased education is positively associated with autonomy in own health care decision making (p make decision in own healthcare. Women from rural area and Terai region needs specific empowerment programme to enable them to be more autonomous in the household decision making. Women's autonomy by education, wealth quintile and development region needs a further social science investigation to observe the variations within each stratum. A more comprehensive strategy can enable women to access community resources, to challenge traditional norms and to access economic resources. This will lead the women to be more autonomous in decision making in the due course.

  14. Prevalence of Swimming Puppy Syndrome in 2,443 Puppies during the Years 2006–2012 in Thailand

    Directory of Open Access Journals (Sweden)

    Korakot Nganvongpanit

    2013-01-01

    Full Text Available The purpose of this study was to report on the prevalence of swimming puppy syndrome (SPS and investigate predisposing factors. Data were recorded from 2,443 puppies (1,183 males and 1,260 females in Thailand, October 2006–September 2012, including breed, sex, number of puppies per litter, type of nest floor, number of affected limbs, and occurrence of pectus excavatum. Fifty-two puppies (2.13% were diagnosed with SPS. The breed most frequently affected was English Bulldog (8.33%. There was no significant difference (P>0.05 between presence and absence of disease based on sex, breed, and nest floor type. The number of puppies per litter was associated with SPS; puppies from smaller litters (1.92 ± 1.12 had a higher prevalence of the disease (P<0.01 than puppies from larger litters (3.64 ± 2.24. Moreover, 15.38% of puppies with affected limbs showed signs of pectus excavatum (8/52; this clinical sign was more prevalent (P<0.01 in puppies with all four limbs affected with SPS.

  15. INDAG newsletter, No. 6, September 2006

    International Nuclear Information System (INIS)

    2006-09-01

    The current issue presents information about the following: recent activities in Nuclear desalination in Member States - The eighth meeting of the International Nuclear Desalination Advisory Group (INDAG), held from 6 to 8 February 2006 at the VIC, Vienna; an overview of El- Dabaa RO experimental facility; coupling of LTMED with KANUPP, Pakistan; highlights of ongoing and future activities of the IAEA (2005-2006)

  16. Die Reichstagswahl 2006 – Eine Zäsur in der schwedischen Parteiengeschichte

    Directory of Open Access Journals (Sweden)

    Sven Jochem

    2006-01-01

    Full Text Available Sweden is the social democratic model in Europe. Despite good economic conditions, the social democratic minority government under the leadership of Göran Persson lost the election on 17th September 2006. Since then, a four party coalition headed by the conservative Prime Minister Fredrik Reinfeldt is governing Sweden. In this contribution the electoral campaign as well as the electoral result is analysed. It will be shown that there occurred a paradigm shift in Swedish party history. A majority government has managed to overcome the programmatic differences in the bourgeois camp. It is further argued that the new government will hardly change the Swedish model at once. However, small but decisive reform steps will alter the contours of the Swedish welfare state and will make it more similar to welfare states in Continental Europe.

  17. Decision rules for decision tables with many-valued decisions

    KAUST Repository

    Chikalov, Igor

    2011-01-01

    In the paper, authors presents a greedy algorithm for construction of exact and partial decision rules for decision tables with many-valued decisions. Exact decision rules can be \\'over-fitted\\', so instead of exact decision rules with many attributes, it is more appropriate to work with partial decision rules with smaller number of attributes. Based on results for set cover problem authors study bounds on accuracy of greedy algorithm for exact and partial decision rule construction, and complexity of the problem of minimization of decision rule length. © 2011 Springer-Verlag.

  18. ENEL Slovenske elektrarne. Annual report 2006

    International Nuclear Information System (INIS)

    2007-01-01

    A brief account of activities carried out by the ENEL Slovenske elektrarne, a.s. (SE) in 2006 year is presented. These activities are reported under the following headings: (1) Evaluation Report and Foreword of the Chairman of the Board of Directors; (2) SE, a.s., Board of Directors in 2006; (3) SE, a.s., Supervisory Board in 2006; (4) The year in brief; (5) SE, a.s., Organisation Structure; (6) Company stakes; (7) Company strategy; (8) Electricity and heat generation; (9) Trade in electricity, support services and heat; (10) Investments; (11) Nuclear safety; (12) Occupational health and safety and fi re protection; (13) Environment; (14) Human resources; (15) Report on Financial Statements and Performance of the Company; (16) Auditor's report; (17) Abbreviations

  19. IMD riikide rahvusvahelise konkurentsivõime aastaraamat 2006 / L Kuum

    Index Scriptorium Estoniae

    Kuum, L

    2006-01-01

    Ilmunud ka: Konjunktuur : Quarterly Review of the Estonian Economy 2006/Aug nr. 2 lk. 49-51.Lausanne'is asuva Juhtimise Arendamise Instituudi (IMD) poolt koostatud riikide rahvusvahelise konkurentsivõime 2006. aasta edetabel. Eesti positsioonist 2006. aasta edetabelis. Tabelid. Graafikud

  20. An assessment tool to ensure compliance for the Imperial Oil Cold Lake operations

    Energy Technology Data Exchange (ETDEWEB)

    Wright, R. [HFP Acoustical Consultants Corp., Calgary, AB (Canada); Nixon, J.K. [Imperial Oil Resources Canada, Calgary, AB (Canada)

    2005-07-01

    In order to address noise issues at Imperial Oil Resources' (IOR) Cold Lake facility, HFP Acoustical Consultants Corp. was hired to develop a noise assessment tool. The innovative tool which has been used successfully by IOR for the past 2 years to self-monitor IOR's predicted sound level contributions for the Cold Lake Operations Lease area, consists of a noise computer model and a noise assessment spreadsheet. The tool is designed to ensure that the sound levels are below those designated by the Alberta Energy and Utilities Board's (EUB) Permissible Sound Level of 40 dBa from a facility to the nearest or most impacted residence. The tool has exceeded design expectations and goals and the spreadsheet has proven to be effective in predicting non-compliance concerns prior to a new facility being constructed or operated. The tool has been incorporated into IOR's corporate project planning process. The tool has shown that the noise contributions from the Cold Lake Lease area are below the EUB Permissible Sound Levels. IOR does not believe that the noise contribution from this area will increase over the life of the project unless a facility is added close to a residence. The IOR-EUB Compliance Self-Assessment Framework, which allows IOR to self-manage noise for its operations, made it possible for IOR to implement this new, site specific regulatory tool which provides accurate, immediate and auditable due-diligence documentation. 6 refs., 2 figs.

  1. Numerical Modeling of the Severe Cold Weather Event over Central Europe (January 2006

    Directory of Open Access Journals (Sweden)

    D. Hari Prasad

    2010-01-01

    Full Text Available Cold waves commonly occur in higher latitudes under prevailing high pressure systems especially during winter season which cause serious economical loss and cold related death. Accurate prediction of such severe weather events is important for decision making by administrators and for mitigation planning. An Advanced high resolution Weather Research and Forecasting mesoscale model is used to simulate a severe cold wave event occurred during January 2006 over Europe. The model is integrated for 31 days starting from 00UTC of 1 January 2006 with 30 km horizontal resolution. Comparison of the model derived area averaged daily mean temperatures at 2m height from different zones over the central Europe with observations indicates that the model is able to simulate the occurrence of the cold wave with the observed time lag of 1 to 3days but with lesser intensity. The temperature, winds, surface pressure and the geopential heights at 500 hPa reveal that the cold wave development associates with the southward progression of a high pressure system and cold air advection. The results have good agreement with the analysis fields indicates that the model has the ability to reproduce the time evolution of the cold wave event.

  2. Værkanalyse 2006

    DEFF Research Database (Denmark)

    2006-01-01

    Kompendiet er en introduktion og en tekstbog i forbindelse med et kursus i værkanalyse, som andetårsstuderende på Kunstakademiets Arkitektskole gennemgik i foråret 2006. Publikationen rummer 10 markante arkitekturmanifester fra det 20. århundrede af arkitekterne Heinrich Tessenow, Le Corbusier...

  3. Utilizing a Web-Based Career Development Workshop to Address Career Decision-Making Difficulty among Community College Distance Learners

    Science.gov (United States)

    Brown, Johanna Michele

    2011-01-01

    Career decision making difficulty, as it relates to undecided college students and career indecision, has been a concern for counselors and academic advisors for decades (Gordon, 2006; Mau, 2004). Individuals struggling with career indecision often seek assistance via career counseling, self-help tools, and/or computer-assisted career guidance…

  4. SN 2006oz

    DEFF Research Database (Denmark)

    Leloudas, Georgios; Chatzopoulos, E.; Dilday, B.

    2012-01-01

    to contribute to a better understanding of these objects by studying SN 2006oz, a newly-recognized member of this class. Methods. We present multi-color light curves of SN 2006oz from the SDSS-II SN Survey that cover its rise time, as well as an optical spectrum that shows that the explosion occurred at z ~ 0.......376. We fitted black-body functions to estimate the temperature and radius evolution of the photosphere and used the parametrized code SYNOW to model the spectrum. We constructed a bolometric light curve and compared it with explosion models. In addition, we conducted a deep search for the host galaxy...... to a recombination wave in a circumstellar medium (CSM) and discuss whether this is a common property of all similar explosions. The subsequent rise can be equally well described by input from a magnetar or by ejecta-CSM interaction, but the models are not well constrained owing to the lack of post...

  5. Spectroscopic Factors from the Single Neutron Transfer Reaction 111Cd(d,p)112Cd

    Science.gov (United States)

    Jamieson, D. S.; Garrett, P. E.; Demand, G. A.; Finlay, P.; Green, K. L.; Leach, K. G.; Phillips, A. A.; Svensson, C. E.; Sumithrarachchi, C. S.; Triambak, S.; Wong, J.; Ball, G.; Faestermann, T.; Krücken, R.; Hertenberger, R.; Wirth, H.-F.

    2013-03-01

    The cadmium isotopes have been cited as excellent examples of vibrational nuclei for decades, with multi-phonon quadrupole, quadrupole-octupole, and mixed-symmetry states proposed. From a variety of experimental studies, a large amount of spectroscopic data has been obtained, recently focused on γ-ray studies. In the present work, the single-particle structure of 112Cd has been investigated using the 111Cd(ěcd, p)112Cd reaction. The investigation was carried out using a 22 MeV beam of polarized deuterons obtained from the Maier-Leibnitz Laboratory at Garching, Germany. The reaction ejectiles were momentum analyzed using a Q3D spectrograph, and 115 levels have been identified up to 4.2 MeV of excitation energy. Spin-parity has been assigned to each analyzed level, and angular distributions for the reaction cross sections and analyzing powers were obtained. Many additional levels have been observed compared with the previous (d,p) study performed with 8 MeV deuterons,1 including strongly populated 5- and 6- states. The former was previously assigned as a member of the quadrupole-octupole quintuplet, based on a strongly enhanced B(E2) value to the 3- state, but is now re-assigned as being predominately s1/2 ⊗ h11/2 configuration.

  6. A survey on new nuclear legislative documents issued in the period 1 October, 2005 - 30 April, 2006

    International Nuclear Information System (INIS)

    Chiripus, Vlad

    2006-01-01

    The paper presents a number of 46 legal documents concerning nuclear problems. issued in the period 1 October, 2005 - 30 April, 2006 in the 'Official Gazette' of Romania (Monitorul Oficial al Romaniei). These documents appear to be decisions of the Romanian Government, decisions of the Dentist Medical College, Ordinances of the National Commission for Nuclear Activities Control, CNCAN, Ordinances of the Ministry of Transports Buildings and Tourism, Ministry of Economy and Trade, Ministry of Public Finances, Ministry of Administration and Internal Affairs, Ministry of Public Health, a presidential decree, laws and regulations. The documents are related to items concerning protection of environment in the neighborhood of nuclear facilities, radioactive sources handling, nuclear licensing, nuclear safeguards, emergency measures in case of nuclear events, financing the construction of Cernavoda NPP Unit 3, radioactive waste management, fast shutdown of CANDU type reactors, etc. Each document mentioned is shortly presented and commented

  7. Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs.

    Science.gov (United States)

    Liu, Yujia; Ji, Xiaoyu; Nie, Xianguang; Qu, Min; Zheng, Lei; Tan, Zilong; Zhao, Huimin; Huo, Lin; Liu, Shengnan; Zhang, Bing; Wang, Yucheng

    2015-08-01

    Plant basic helix-loop-helix (bHLH) transcription factors play essential roles in abiotic stress tolerance. However, most bHLHs have not been functionally characterized. Here, we characterized the functional role of a bHLH transcription factor from Arabidopsis, AtbHLH112, in response to abiotic stress. AtbHLH112 is a nuclear-localized protein, and its nuclear localization is induced by salt, drought and abscisic acid (ABA). In addition, AtbHLH112 serves as a transcriptional activator, with the activation domain located at its N-terminus. In addition to binding to the E-box motifs of stress-responsive genes, AtbHLH112 binds to a novel motif with the sequence 'GG[GT]CC[GT][GA][TA]C' (GCG-box). Gain- and loss-of-function analyses showed that the transcript level of AtbHLH112 is positively correlated with salt and drought tolerance. AtbHLH112 mediates stress tolerance by increasing the expression of P5CS genes and reducing the expression of P5CDH and ProDH genes to increase proline levels. AtbHLH112 also increases the expression of POD and SOD genes to improve reactive oxygen species (ROS) scavenging ability. We present a model suggesting that AtbHLH112 is a transcriptional activator that regulates the expression of genes via binding to their GCG- or E-boxes to mediate physiological responses, including proline biosynthesis and ROS scavenging pathways, to enhance stress tolerance. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

  8. Individuals with 22q11.2 Deletion Syndrome Are Impaired at Explicit, but Not Implicit, Discrimination of Local Forms Embedded in Global Structures

    Science.gov (United States)

    Giersch, Anne; Glaser, Bronwyn; Pasca, Catherine; Chabloz, Mélanie; Debbané, Martin; Eliez, Stephan

    2014-01-01

    Individuals with 22q11.2 deletion syndrome (22q11.2DS) are impaired at exploring visual information in space; however, not much is known about visual form discrimination in the syndrome. Thirty-five individuals with 22q11.2DS and 41 controls completed a form discrimination task with global forms made up of local elements. Affected individuals…

  9. Impact of reserves information on formulating government policy

    International Nuclear Information System (INIS)

    Ekelund, M.W.; Anderson, B.; Khan, M.; Hudson, B.

    1997-01-01

    Policies regarding the development and production of Alberta's mineral resources such as oil, gas, and bitumen, are developed by the Alberta Ministry of Energy. The Ministry is divided into the Energy and Utilities Board (EUB) and the Department of Energy. The EUB deals with conservation, production measurement and reporting, environmental issues and some public utility issues. The Department of Energy deals with determining the appropriate fiscal and tenure regimes, market effectiveness issues and collection of Alberta's share of production. Reserve estimates are used for policy development and implementation purposes. The impact of some doubts regarding the reliability of reserves information and its impact on provincial policy recommendations were highlighted. Examples were drawn from bitumen reserves determination in the Athabasca Oil Sands area, enhanced oil recovery programs within the conventional oil sector, and royalty formulation within the conventional oil and gas sectors

  10. Decision rules for decision tables with many-valued decisions

    KAUST Repository

    Chikalov, Igor; Zielosko, Beata

    2011-01-01

    In the paper, authors presents a greedy algorithm for construction of exact and partial decision rules for decision tables with many-valued decisions. Exact decision rules can be 'over-fitted', so instead of exact decision rules with many attributes

  11. Single- versus dual-process models of lexical decision performance: insights from response time distributional analysis.

    Science.gov (United States)

    Yap, Melvin J; Balota, David A; Cortese, Michael J; Watson, Jason M

    2006-12-01

    This article evaluates 2 competing models that address the decision-making processes mediating word recognition and lexical decision performance: a hybrid 2-stage model of lexical decision performance and a random-walk model. In 2 experiments, nonword type and word frequency were manipulated across 2 contrasts (pseudohomophone-legal nonword and legal-illegal nonword). When nonwords became more wordlike (i.e., BRNTA vs. BRANT vs. BRANE), response latencies to nonwords were slowed and the word frequency effect increased. More important, distributional analyses revealed that the Nonword Type = Word Frequency interaction was modulated by different components of the response time distribution, depending on the specific nonword contrast. A single-process random-walk model was able to account for this particular set of findings more successfully than the hybrid 2-stage model. (c) 2006 APA, all rights reserved.

  12. The Number of Genomic Copies at the 16p11.2 Locus Modulates Language, Verbal Memory, and Inhibition.

    Science.gov (United States)

    Hippolyte, Loyse; Maillard, Anne M; Rodriguez-Herreros, Borja; Pain, Aurélie; Martin-Brevet, Sandra; Ferrari, Carina; Conus, Philippe; Macé, Aurélien; Hadjikhani, Nouchine; Metspalu, Andres; Reigo, Anu; Kolk, Anneli; Männik, Katrin; Barker, Mandy; Isidor, Bertrand; Le Caignec, Cédric; Mignot, Cyril; Schneider, Laurence; Mottron, Laurent; Keren, Boris; David, Albert; Doco-Fenzy, Martine; Gérard, Marion; Bernier, Raphael; Goin-Kochel, Robin P; Hanson, Ellen; Green Snyder, LeeAnne; Ramus, Franck; Beckmann, Jacques S; Draganski, Bogdan; Reymond, Alexandre; Jacquemont, Sébastien

    2016-07-15

    Deletions and duplications of the 16p11.2 BP4-BP5 locus are prevalent copy number variations (CNVs), highly associated with autism spectrum disorder and schizophrenia. Beyond language and global cognition, neuropsychological assessments of these two CNVs have not yet been reported. This study investigates the relationship between the number of genomic copies at the 16p11.2 locus and cognitive domains assessed in 62 deletion carriers, 44 duplication carriers, and 71 intrafamilial control subjects. IQ is decreased in deletion and duplication carriers, but we demonstrate contrasting cognitive profiles in these reciprocal CNVs. Deletion carriers present with severe impairments of phonology and of inhibition skills beyond what is expected for their IQ level. In contrast, for verbal memory and phonology, the data may suggest that duplication carriers outperform intrafamilial control subjects with the same IQ level. This finding is reminiscent of special isolated skills as well as contrasting language performance observed in autism spectrum disorder. Some domains, such as visuospatial and working memory, are unaffected by the 16p11.2 locus beyond the effect of decreased IQ. Neuroimaging analyses reveal that measures of inhibition covary with neuroanatomic structures previously identified as sensitive to 16p11.2 CNVs. The simultaneous study of reciprocal CNVs suggests that the 16p11.2 genomic locus modulates specific cognitive skills according to the number of genomic copies. Further research is warranted to replicate these findings and elucidate the molecular mechanisms modulating these cognitive performances. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  13. POWERNEXT Carbon statistics September 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 trading market, for the July-September 2006 period: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The monthly volumes and closing prices for the September 2005 - September 2006 era are summarized in a graphics. (J.S.)

  14. POWERNEXT Carbon statistics November 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 trading market, for the September-November 2006 period: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The monthly volumes and closing prices for the November 2005 - November 2006 era are summarized in a graphics. (J.S.)

  15. Powernext Carbon statistics - June 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 quotas trading market, for the second quarter of 2006: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The monthly volumes and closing prices from June 2005 to June 2006 are summarized in a graphics. (J.S.)

  16. POWERNEXT Carbon statistics October 31, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 trading market, for the August-October 2006 period: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The monthly volumes and closing prices for the October 2005 - October 2006 era are summarized in a graphics. (J.S.)

  17. Powernext Carbon statistics - May 31, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 quotas trading market, for March, April and May 2006: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The daily volume and closing price from June 2005 to May 2006 are summarized in a graphics. (J.S.)

  18. Arhitektuuriaasta 2006 = The year in architecture 2006 / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2007-01-01

    Eesti Kultuurkapitali aastapreemia 2006 saanutest. Peaauhinna sai Raine Karp, restaureerimispreemia Mart Kalm ja Ado Talimaa (O. Siinmaa villa ja mööbli restaureerimine), parima arhitektuurse objekti preemia Andrus Kõresaar ja Raivo Kotov (Fahle maja), sisekujunduspreemia Tarmo Piirmets (Skype'i büroo), arhitektuurialase uurimuse preemia Mart Siilivask ("Tartu arhitektuur 1830-1918"), disainipreemia Eesti Disainerite Liit

  19. Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

    DEFF Research Database (Denmark)

    Horne, Hisani N; Chung, Charles C; Zhang, Han

    2016-01-01

    rs11249433 in 45,276 breast cancer cases and 48,998 controls of European, Asian and African ancestry from 50 studies in the Breast Cancer Association Consortium. Genotyping was done using iCOGS, a custom-built array. Due to the complicated nature of the region on chr1p11.2: 120......The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identified a single nucleotide polymorphism (SNP) rs11249433 at 1p11.2 associated with breast cancer risk. To fine-map this locus, we genotyped 92 SNPs in a 900kb region (120,505,799-121,481,132) flanking......,300,000-120,505,798, that lies near the centromere and contains seven duplicated genomic segments, we restricted analyses to 429 SNPs excluding the duplicated regions (42 genotyped and 387 imputed). Per-allelic associations with breast cancer risk were estimated using logistic regression models adjusting for study and ancestry...

  20. Technical training: AXEL-2006 - Introduction to Particle Accelerators

    CERN Multimedia

    Davide Vitè

    2006-01-01

    CERN Technical Training 2006: Learning for the LHC! AXEL-2006 is a course series on particle accelerators, given at CERN within the framework of the 2006 Technical Training Programme. Known in the past as the PS Complex Operation Course (or the 'PS Shutdown Course'), the general accelerator physics module is organised since 2003 as a joint venture between the AB department and Technical Training, and is open to a wider CERN community. The AXEL-2006 course series is designed for technicians who are operating an accelerator, or whose work is closely linked to accelerators, but it is open to technicians, engineers, and physicists interested in this field. The course does not require any prior knowledge on accelerators. However, some basic knowledge on trigonometry, matrices and differential equations, and some basic notions of magnetism would be an advantage. The course series will be composed of 10 one-hour lectures (mornings and afternoons) during the week 6-10 February March 2006, and given in English...

  1. Comparing the broad socio-cognitive profile of youth with Williams syndrome and 22q11.2 deletion syndrome.

    Science.gov (United States)

    Weisman, O; Feldman, R; Burg-Malki, M; Keren, M; Geva, R; Diesendruck, G; Gothelf, D

    2017-12-01

    Numerous studies have assessed the socio-cognitive profile in Williams syndrome (WS) and, independently, in 22q11.2 deletion syndrome (22q11.2DS). Yet, a cross-syndrome comparison of these abilities between individuals with these two syndromes with known social deficits has not been conducted. Eighty-two children participated in four study groups: WS (n = 18), 22q112.DS (n = 24), age-matched individuals with idiopathic developmental disability (IDD; n = 20) and typically developing (TD) controls (n = 20). Participants completed four socio-cognitive tests: facial emotion recognition, mental state attribution, differentiating real from apparent emotions and trait inference based on motives and actions-outcomes. The current findings demonstrate that children with WS were better in labelling happy faces compared with children with 22q11.2DS, partially reflecting their exaggerated social drive. In the false belief task, however, the WS and IDD groups performed poorly compared with the 22q11.2DS group, possibly due to their difficulty to interpret subtle social cues. When asked to identify the gap between real-negative vs. apparent-positive emotions, the 22q11.2DS group performed similarly to TD children but better than the WS group, possibly due to their anxious personality and their innate bias towards negatively valence cues. Finally, individuals with WS were more willing to become friends with a story character even when the character's motives were negative, reflecting their difficulty to avoid potentially harmful real-life situations. Overall, our multi-facet socio-cognitive battery uncovered strengths and weaknesses in social cognition that are syndrome-specific, shared among the genetic syndromes, or common to the three clinical groups compared with healthy controls. Our findings underscore the need to devise age-specific and condition-specific assessment tools and intervention programs towards improving these children's socio-cognitive deficits. © 2017

  2. System dependence of the correlation function of IMFs in 36Ar + 112,124Sn at 35 MeV/u

    International Nuclear Information System (INIS)

    Xiao, Z.G.; Hu, R.J.; Wu, H.Y.; Jin, G.M.; Li, Z.Y.; Duan, L.M.; Wang, H.W.; Zhang, B.G.; Wang, S.F.; Wei, Z.Y.; Xu, H.S.; Zhu, Y.T.; Li, S.L.; Fu, F.; Yuan, X.H.; Feng, Z.Q.

    2006-01-01

    The inclusive reduced velocity correlation functions of the intermediate mass fragments were measured in the reactions of 36 Ar + 112,124 Sn at 35 MeV/u. The anti-correlation is observed to be stronger in 36 Ar + 124 Sn system than that in 36 Ar + 112 Sn. The difference of the correlation functions between the two reactions is mainly contributed by the particle pairs with high momenta. A three body Coulomb repulsive trajectory model is employed to calculate the emission time scale of the IMFs for the two systems. The time scale is 150 fm/c in 36 Ar + 112 Sn and 120 fm/c in the 36 Ar + 124 Sn, respectively

  3. Areva half-year report june 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This document is the half-year financial report of the Areva group for 2006. It presents: 1 - Highlights of the period; 2 - Key data: Summary data, Segment reporting, Backlog, Income statement, Review by business division, Cash flow, Balance sheet data; 3 - Outlook; 4 - Events subsequent to the half-year end; 5 - Consolidated financial statements: Statutory auditors' report on the interim consolidated financial statements for the period January 1, 2006 to June 30, 2006, Consolidated income statement, Consolidated balance sheet, Consolidated cash flow statement, Consolidated statement of changes in equity, Segment reporting, Notes to the consolidated financial statements

  4. Analysis of 22q11.2 deletions by FISH in a series of velocardiofacial syndrome patients

    Energy Technology Data Exchange (ETDEWEB)

    Ravnan, J.B.; Golabi, M.; Lebo, R.V. [Univ. of California, San Francisco, CA (United States)

    1994-09-01

    Deletions in chromosome 22 band q11.2 have been associated with velocardiofacial (VCF or Shprintzen) syndrome and the DiGeorge anomaly. A study of VCF patients evaluated at the UCSF Medical Center was undertaken to correlate disease phenotype with presence or absence of a deletion. Patients referred for this study had at least two of the following: dysmorphic facial features, frequent ear infections or hearing loss, palate abnormalities, thymic hypoplasia, hypocalcemia, congenital heart defect, hypotonia, and growth or language delay. Fluorescence in situ hybridization (FISH) using the DiGeorge critical region probe N25 was used to classify patients according to the presence or absence of a deletion in 22q11.2, and the results were compared to clinical characteristics. We have completed studies on 58 patients with features of VCF. Twenty-one patients (36%) were found to have a deletion in 22q11.2 by FISH. A retrospective study of archived slides from 14 patients originally studied only by prometaphase GTG banding found six patients had a deletion detected by FISH; of these, only two had a microscopically visible chromosome deletion. Our study of 11 sets of parents of children with the deletion found two clinically affected mothers with the deletion, including one with three of three children clinically affected. A few patients who did not fit the classical VCF description had a 22q11.2 deletion detected by FISH. These included one patient with both cleft lip and palate, and another with developmental delay and typical facial features but no cardiac or palate abnormalities. Both patients with the DiGeorge anomaly as part of VCF had the deletion. On the other hand, a number of patients diagnosed clinically with classical VCF did not have a detectable deletion. This raises the question whether they represent a subset of patients with a defect of 22q11.2 not detected by the N25 probe, or whether they represent a phenocopy of VCF.

  5. The United States Revised Uniform Anatomical Gift Act (2006: New challenges to balancing patient rights and physician responsibilities

    Directory of Open Access Journals (Sweden)

    McGregor Joan L

    2007-09-01

    Full Text Available Abstract Advance health care directives and informed consent remain the cornerstones of patients' right to self-determination regarding medical care and preferences at the end-of-life. However, the effectiveness and clinical applicability of advance health care directives to decision-making on the use of life support systems at the end-of-life is questionable. The Uniform Anatomical Gift Act (UAGA has been revised in 2006 to permit the use of life support systems at or near death for the purpose of maximizing procurement opportunities of organs medically suitable for transplantation. Some states have enacted the Revised UAGA (2006 and a few of those have included amendments while attempting to preserve the uniformity of the revised Act. Other states have introduced the Revised UAGA (2006 for legislation and remaining states are likely to follow soon. The Revised UAGA (2006 poses challenges to the Patient Self Determination Act (PSDA embodied in advance health care directives and individual expression about the use of life support systems at the end-of-life. The challenges are predicated on the UAGA revising the default choice to presumption of donation intent and the use of life support systems to ensure medical suitability of organs for transplantation. The default choice trumps the expressed intent in an individual's advance health care directive to withhold and/or withdraw life support systems at the end-of-life. The Revised UAGA (2006 overrides advance directives on utilitarian grounds, which is a serious ethical challenge to society. The subtle progression of the Revised UAGA (2006 towards the presumption about how to dispose of one's organs at death can pave the way for an affirmative "duty to donate". There are at least two steps required to resolve these challenges. First, physicians and hospitals must fulfill their responsibilities to educate patients on the new legislations and document their preferences about the use of life support

  6. Annual report 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    This report represents all the activities and accomplishment of Philippine Nuclear Research Institute (PNRI) for the calendar year 2006 which cited the activities of diffusion of knowledge and technologies; generation of new knowledge and technologies; provision of quality S and T services; linking and net working; and development of human resources.

  7. Annual report 2006

    International Nuclear Information System (INIS)

    2007-01-01

    This report represents all the activities and accomplishment of Philippine Nuclear Research Institute (PNRI) for the calendar year 2006 which cited the activities of diffusion of knowledge and technologies; generation of new knowledge and technologies; provision of quality S and T services; linking and net working; and development of human resources

  8. Evaluation of Palm PCRTM G1-12 System: a portable battery-operated PCR thermal cycler

    Directory of Open Access Journals (Sweden)

    Siti Aminah Ahmed

    2016-08-01

    Full Text Available Polymerase chain reaction (PCR is the basis of recombinant and other molecular biological techniques. Availability of cheap and robust PCR platforms enables the tests to be performed easily, even in resource constrained settings. Herein we compared the efficacy of a portable thermal cycler ( Palm PCRTM G1-12 System for rapid DNA amplification against the standard Peltier-based thermal cycler using plasmid DNA and genomic DNA in single and multiplex PCR experiments. Our study revealed that the Palm PCRTM G1-12 System could be a portable DNA amplification system to conduct various molecular techniques, especially in places where resources are limited.

  9. Powernext FuturesTM statistics. April 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the April 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for April 2006, base-load and peak-load contracts overview from November 2005 to April 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period), and market liquidity in April 2006 (average bid ask spread and availability for base-load and peak-load contracts). (J.S.)

  10. Nonattainment Areas in Louisiana, Geographic NAD83, EPA (2006) [Nonattainment_LA_EPA_2006

    Data.gov (United States)

    Louisiana Geographic Information Center — EPA Region 6 NonAttainment Areas in Louisiana, current as of May 2006. This shapefile contains parish boundaries and attributes that determine whether the parishes...

  11. Powernext Carbon statistics - March 31, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This short document summarizes the statistics of Powernext Carbon, the European CO 2 quotas trading market, for the first quarter of 2006: total market volume, daily average, highest, number and average size of trades, number of members, average closing price, variation, low and high traded. The daily volume and closing price from June 2005 to March 2006 are summarized in a graphics and a members list is supplied. (J.S.)

  12. Hematological abnormalities and 22q11.2 deletion syndrome

    Directory of Open Access Journals (Sweden)

    Rafael Fabiano Machado Rosa

    2011-01-01

    Full Text Available The 22q11.2 deletion syndrome (22q11DS is a common genetic disease characterized by broad phenotypic variability. Despite the small number of studies describing hematological alterations in individuals with 22q11DS, it appears that these abnormalities are more frequent than previously imagined. Thus, the objective of our study was to report on a patient with 22q11DS presenting thrombocytopenia and large platelets and to review the literature. The patient, a 13-year-old boy, was originally evaluated due to craniofacial dysmorphia and speech delay. He also had a history of behavioral changes, neuropsychomotor delay and recurrent otitis/sinusitis. The identification of a 22q11.2 microdeletion by fluorescent in situ hybridization diagnosed the syndrome. Despite his hematological alterations, he only had a history of epistaxis and bruising of the upper and lower limbs. Assessments of the prothrombin time, thrombin time, partial thromboplastin time, bleeding time, fibrinogen levels and platelet aggregation (including the ristocetin induced platelet aggregation test were all normal. Hematological alterations observed in 22q11DS are directly related to the genetic disorder itself (especially in respect to deletion of the GPIb gene and secondary to some clinical findings, such as immunodeficiency. Macrothrombocytopenia is increasingly being considered a feature of the broad spectrum of 22q11DS and may potentially be a clinical marker for the syndrome.

  13. Final disposal of spent nuclear fuel in Sweden: The evolving role for KASAM when society is preparing for important decisions

    International Nuclear Information System (INIS)

    Glimelius, Kristina; Hedberg, Bjoern; Norrby, Soeren; Soederberg, Olof

    2006-01-01

    KASAM, the Swedish National Council for Nuclear Waste, is an independent scientific council attached to the Ministry of Sustainable Development. The members of KASAM are independent scientists within a wide range of areas of importance for the final disposal of radioactive waste, not only within technology and natural sciences but also within areas such as ethics and social sciences. Swedish nuclear waste management policy and implementation is currently in a protracted phase of planning and decisions. Starting in 2006 , the Swedish Nuclear Waste Management Co (SKB) is expected to submit the necessary applications for permits to construct an encapsulation facility and a disposal facility for spent nuclear fuel (in crystalline bedrock about 500 meters below the ground). According to Swedish legislation, basic permits have to be granted by the Government, but the Government will not grant such permits unless the concerned host municipality accepts the proposal. The Government decision will form the basis for detailed licensing decisions by the regulatory authorities. KASAM has an important role as an independent advisory body to the Ministry of Sustainable Development. Also, KASAM will continue its function of creating forums for dialogue that could contribute to increase knowledge and understanding and improve the knowledge base for decision-making. There are a number of questions that are relevant. Examples are: Will society have a satisfactory basis for decision-making? What happens if society is not capable of making necessary decisions? Does the decision-making process enable society to postpone important decisions if more time is needed, to avoid obstacles if they appear, and - if needed - reverse decisions? Considering issues like this, KASAM has set up a plan for its activities in the next few years. These activities are meant to contribute to the ability of society as a whole to arrive at a well-founded decision that is widely accepted. Based on facts

  14. 15 CFR 2006.3 - Determinations regarding petitions.

    Science.gov (United States)

    2010-01-01

    ..., including but not limited to a domestic firm or worker, a representative of consumer interests, a United... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Determinations regarding petitions. 2006.3 Section 2006.3 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements...

  15. 1+1+2 gravitational perturbations on LRS class II spacetimes: decoupling gravito-electromagnetic tensor harmonic amplitudes

    International Nuclear Information System (INIS)

    Burston, R B

    2008-01-01

    This is the first in a series of papers which considers gauge-invariant and covariant gravitational perturbations on arbitrary vacuum locally rotationally symmetric (LRS) class II spacetimes. Ultimately, we derive four decoupled equations governing four specific combinations of the gravito-electromagnetic (GEM) 2-tensor harmonic amplitudes. We use the gauge-invariant and covariant 1+1+2 formalism which Clarkson and Barrett (2003 Class. Quantum Grav. 20 3855) developed for analysis of vacuum Schwarzschild perturbations. In particular we focus on the first-order 1+1+2 GEM system and use linear algebra techniques suitable for exploiting its structure. Consequently, we express the GEM system new 1+1+2 complex form by choosing new complex GEM tensors, which is conducive to decoupling. We then show how to derive a gauge-invariant and covariant decoupled equation governing a newly defined complex GEM 2-tensor. Finally, the GEM 2-tensor is expanded in terms of arbitrary tensor harmonics and linear algebra is used once again to decouple the system further into four real decoupled equations

  16. Congenital Arthrogryposis: An Extension of the 15q11.2 BP1-BP2 Microdeletion Syndrome?

    Directory of Open Access Journals (Sweden)

    K. M. Usrey

    2014-01-01

    Full Text Available The proximal 15q11–q13 region contains 5 breakpoints (BP1–BP5. The BP1-BP2 region spans approximately 500 kb and contains four evolutionarily conserved genes. The genes in this region are known to play a role in central nervous system development and/or function. Microdeletions within the 15q11.2 BP1-BP2 region have been reported in patients with neurological dysfunction, developmental delays, behavioral problems, and dysmorphic features. We report two unrelated subjects with the 15q11.2 BP1-BP2 microdeletion and presenting with congenital arthrogryposis, a feature which has not been previously reported as part of this newly recognized microdeletion syndrome. While arthrogryposis seen in these two subjects may be coincidental, we propose that congenital arthrogryposis may result from neurological dysfunction and involvement of the microdeletion of the 15q11.2 BP1-BP2 region, further expanding the phenotype of this microdeletion syndrome. We encourage others to report patients with this chromosome microdeletion and neurological findings to further characterize the clinical phenotype.

  17. Annual survey air quality 2003-2006

    International Nuclear Information System (INIS)

    Beijk, R.; Mooibroek, D.; Hoogerbrugge, R.

    2007-01-01

    Results from the Dutch National Air Quality Monitoring Network (LML) show that several European air quality limit values were exceeded in the Netherlands between 2003 and 2006. This applied mainly to nitrogen dioxide, particulate matter (PM10) and ozone. The number of exceedances was especially high in 2003, partly due to weather conditions such as enduring dry episodes. Ozone concentration levels above the alert threshold (smog alert) were measured in 2003 and 2006, with concentration levels above the alert threshold occurring mostly during heat episodes. Measurements for nitrogen dioxide showed a yearly average concentration at city street locations above the European limit value at approximately half the measuring sites between 2003 and 2006. Yearly average concentrations measured at regional locations have changed relatively little in the past four years, remaining below the limit value for this entire period. Particulate matter concentrations have been relatively constant in the past few three years, after peaking in 2003. There is an EU standard for particulate matter for short- and long-term exposure of the population, which is represented by year and day average concentrations, with a maximum number of exceedances per year allowed. The year averages for the 2003 to 2006 period are less than the standard for long-term exposure. The maximum number of days showing average concentrations above the limit value was violated at several locations in 2006. Both nitrogen dioxide and particulate matter are characterized by a clear downward trend when measured over a long period of time (15 and 14 years, respectively). However, it is not possible to determine from the past seven years whether this trend is still valid [nl

  18. RTE - annual report 2006

    International Nuclear Information System (INIS)

    2006-01-01

    RTE is the French electricity transmission system operator responsible for operation, maintenance and development, With a system which is the largest in Europe - 100,000 kilometres of high voltage and extra-high voltage circuits and 46 cross-border interconnections, plus a key location at the geographical hub - RTE is playing a key role in the development of the European electricity market. RTE is a public service company guaranteeing the efficient operation and reliability of the French power system, and providing equitable access to all system users. The company is part of the EDF Group, but has totally independent management and administration, as required by law. In 2005, RTE became a limited liability company with an Executive Board and Supervisory Board; this corporate status guarantees due neutrality in providing service to all players on the electricity market. RTE is the Number 1 electricity transmission system in Europe with 8,300 employees and 4 billion euros turnover. This activity report presents: 1 - Background: The RTE Transmission System, Message from the Chairman of the Executive Board; 2 - A High Performance Public Service Company at the Hub of the European Electricity Market: 2006 overview and Highlights, RTE Governance and Organisation; 3 - A Year with Many Developments: Satisfied Customers on a More Efficient Market, Reliable, Upgraded Industrial Facilities, A Commitment to Environmentally Friendly Public Service, New Foundations for Human Resources Policy, International Business on the Move, A Good Improvement in Financial Performance; 4 - Glossary; 5 - Management Report: Financial and Legal Information (Highlights in 2006, Market Trends, Business and Results for 2006, Capital, Financial Structure, Prospects for 2007, Other Financial and Legal Information), Information on the Environment (Environment Policy - Review, Respect for Natural Environments and Landscapes, Consultation and Consideration, Research, Continuing Improvement, Environmental

  19. Motion of 1/3⟨111⟩ dislocations on Σ3 {112} twin boundaries in nanotwinned copper

    Science.gov (United States)

    Lu, N.; Du, K.; Lu, L.; Ye, H. Q.

    2014-01-01

    The atomic structure of Σ3 {112} ITBs in nanotwinned Cu is investigated by using aberration-corrected high resolution transmission electron microscopy (HRTEM) and in situ HRTEM observations. The Σ3 {112} ITBs are consisted of periodically repeated three partial dislocations. The in situ HRTEM results show that 1/3[111] partial dislocation moves on the Σ3 {112} incoherent twin boundary (ITB), which was accompanied by a migration of the ITB. A dislocation reaction mechanism is proposed for the motion of 1/3[111] Frank partial dislocation, in which the 1/3[111] partial dislocation exchanges its position with twin boundary dislocations in sequence. In this way, the 1/3[111] dislocation can move on the incoherent twin boundary in metals with low stacking fault energy. Meanwhile, the ITB will migrate in its normal direction accordingly. These results provide insight into the reaction mechanism of 1/3[111] dislocations and ITBs and the associated migration of ITBs.

  20. The VAEC - Annual Report for 2006

    International Nuclear Information System (INIS)

    Vuong Huu Tan; Le Van Hong; Nguyen Hoang Anh; Nguyen Trong Trang; Dang Thi Hong

    2007-12-01

    The VAEC Annual Report for 2006 has been prepared as an account of works carried out at the Vietnam Atomic Energy Commission (VAEC) for the year 2006. The Report contains mains results from the VAEC's activities of research and development in following fields: nuclear physics, reactor physics and nuclear energy, nuclear methods, radiation protection and radioactive waste management, ecology and environment, biotechnology and agriculture, radiation technology, radiochemistry and materials sciences, computation and other topics. (NHA)

  1. The VAEC - Annual Report for 2006

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Vuong Huu; Hong, Le Van; Anh, Nguyen Hoang; Trang, Nguyen Trong; Hong, Dang Thi [eds.

    2007-12-15

    The VAEC Annual Report for 2006 has been prepared as an account of works carried out at the Vietnam Atomic Energy Commission (VAEC) for the year 2006. The Report contains mains results from the VAEC's activities of research and development in following fields: nuclear physics, reactor physics and nuclear energy, nuclear methods, radiation protection and radioactive waste management, ecology and environment, biotechnology and agriculture, radiation technology, radiochemistry and materials sciences, computation and other topics. (NHA)

  2. Contribution of systematic reviews to management decisions.

    Science.gov (United States)

    Cook, Carly N; Possingham, Hugh P; Fuller, Richard A

    2013-10-01

    Systematic reviews comprehensively summarize evidence about the effectiveness of conservation interventions. We investigated the contribution to management decisions made by this growing body of literature. We identified 43 systematic reviews of conservation evidence, 23 of which drew some concrete conclusions relevant to management. Most reviews addressed conservation interventions relevant to policy decisions; only 35% considered practical on-the-ground management interventions. The majority of reviews covered only a small fraction of the geographic and taxonomic breadth they aimed to address (median = 13% of relevant countries and 16% of relevant taxa). The likelihood that reviews contained at least some implications for management tended to increase as geographic coverage increased and to decline as taxonomic breadth increased. These results suggest the breadth of a systematic review requires careful consideration. Reviews identified a mean of 312 relevant primary studies but excluded 88% of these because of deficiencies in design or a failure to meet other inclusion criteria. Reviews summarized on average 284 data sets and 112 years of research activity, yet the likelihood that their results had at least some implications for management did not increase as the amount of primary research summarized increased. In some cases, conclusions were elusive despite the inclusion of hundreds of data sets and years of cumulative research activity. Systematic reviews are an important part of the conservation decision making tool kit, although we believe the benefits of systematic reviews could be significantly enhanced by increasing the number of reviews focused on questions of direct relevance to on-the-ground managers; defining a more focused geographic and taxonomic breadth that better reflects available data; including a broader range of evidence types; and appraising the cost-effectiveness of interventions. © 2013 The Authors. Conservation Biology published by Wiley

  3. Hard probes 2006 Asilomar

    CERN Multimedia

    2006-01-01

    "The second international conference on hard and electromagnetic probes of high-energy nuclear collisions was held June 9 to 16, 2006 at the Asilomar Conference grounds in Pacific Grove, California" (photo and 1/2 page)

  4. Annual Report 2006

    International Nuclear Information System (INIS)

    Gawlikowicz, W.; Pienkowski, L.

    2007-03-01

    The Annual Report of the Heavy Ion Laboratory, Warsaw University describes the activities of Laboratory in 2006. The document consist of four parts: 'Laboratory Overview', 'Experiments and Experimental Set-ups', 'Experiments Using the Outside Facilities' and 'General Information on HIL Activities'. An 'Introduction' written by director of the Department prof. J. Jastrzebski is also given

  5. Plim + Plex 2006

    International Nuclear Information System (INIS)

    2006-01-01

    This document gathers only the program and the transparencies of about half the contributions to this 2006 conference on plant life management (PLIM) and plant licence extension (PLEX). The topics addressed are: -) technical aspects of nuclear power plant ageing, -) plant life management in different countries like Usa, France, South-Africa, Germany, Mexico..., and -) licence renewal

  6. Plim + Plex 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This document gathers only the program and the transparencies of about half the contributions to this 2006 conference on plant life management (PLIM) and plant licence extension (PLEX). The topics addressed are: -) technical aspects of nuclear power plant ageing, -) plant life management in different countries like Usa, France, South-Africa, Germany, Mexico..., and -) licence renewal.

  7. A Decision Model for Merging Base Operations: Outsourcing Pest Management on Joint Base Anacostia-Bolling

    Science.gov (United States)

    2011-11-30

    OH: South- Western Cengage Learning. Mankiw , N. G. (2006). Principles of economics (4th ed.). Mason, OH: Thompson South- Western. Private...When the choice to in-source or outsource an installation function or service requirement exists, in these challenging economic times, it is now more...decision uncertainties. When the choice to in-source or outsource an installation function or service requirement exists, in these challenging economic

  8. Trisomy 2q11.2-->q21.1 resulting from an unbalanced insertion in two generations.

    Science.gov (United States)

    Glass, I A; Stormer, P; Oei, P T; Hacking, E; Cotter, P D

    1998-01-01

    In this communication, we describe two cases of proximal 2q trisomy (2q11.2--> q21.1) resulting from an interchromosomal insertion. The chromosomal origin of the insertion was confirmed by fluorescence in situ hybridisation. An unbalanced karyotype, 46,XX,der(8) ,ins(8;2) (p21.3; q21.1q11.2), was found in the proband and her mother, who both have mild mental retardation, short stature, dysmorphic features, insulin dependent diabetes mellitus, and a psychotic illness. This family is a rare example of direct transmission of a partial autosomal trisomy. Images PMID:9598728

  9. The LNG Industry in 2006

    International Nuclear Information System (INIS)

    Anon.

    2007-01-01

    Estimates for the marketed production of natural gas in 2006 show a rise of about 3% over 2005. The share of LNG in the gas trade accounts for 23% of the total. In 2006, the international trade in liquid form accounted for 348.4 10 6 m 3 or almost 159 10 6 t. It rose by 38.4 10 6 m 3 , or 12.4%, the highest growth rate ever recorded over the last decade. As to imports: - Japan remained by far the world's largest LNG importer with 136 10 6 m 3 , or 39% of all imports, followed by Korea with 55.3 10 6 m 3 (15.9%) and Spain with 41.6 10 6 m 3 (12.0%), markedly higher than the U.S.A. ranking fourth with 26 10 6 m 3 (7.5%). Seventeen countries were involved in LNG imports with the addition of China and Mexico in 2006. - The growth rate of European imports remained stable at 21%, above the global growth rate of 12.4%, resulting in a market share for Europe of 27.4% and demonstrating the dynamism of this region in the LNG trade. With a 12% market share in worldwide trade, Spain maintained its position as Europe's largest LNG market. - After substantial increases during the early part of this decade, the US market suffered most from the shortage in LNG production and price arbitration prompted some shippers to divert spot LNG away from the US market. Imports for the Americas as a whole still decreased by 3.2% and their global market share fell to 8.5%. - The Asian market kept on growing steadily by 11.4% with imports to the region rising from 200.6 10 6 m 3 to 223.4 10 6 m 3 or an increase of 22.8 10 6 m 3 , mainly due to the continued rise of Indian imports with a 3.9% market share, and the emergence of China on the LNG scene. Japanese imports steadily rose to 136 10 6 m 3 . Korea also enjoyed a significant growth by 13.5% to 55.3 10 6 m 3 while Taiwan's imports grew by 8.5% to 17 10 6 m 3 . As to sources of imports: Indonesia lost its leading position and Qatar became the world's largest LNG producer with 15.5% of all exports. Indonesia ranked second with 13.9%, Malaysia

  10. Scientific Report 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-09-15

    The annual scientific report gives a summary overview of the research and development activities at the Belgian Nuclear Research Centre SCK-CEN in 2006. The report discusses progress and main achievements in the following areas: reactor safety, radioactive waste and clean-up, radiation protection, the BR2 reactor, nuclear research and society, managing nuclear knowledge and fusion research.

  11. Scientific Report 2006

    International Nuclear Information System (INIS)

    2007-09-01

    The annual scientific report gives a summary overview of the research and development activities at the Belgian Nuclear Research Centre SCK-CEN in 2006. The report discusses progress and main achievements in the following areas: reactor safety, radioactive waste and clean-up, radiation protection, the BR2 reactor, nuclear research and society, managing nuclear knowledge and fusion research

  12. JUNE 2006 make up

    African Journals Online (AJOL)

    Winnie

    2006-06-02

    Jun 2, 2006 ... coverage is below par given its economic, institutional and .... Mexico. Malaysia. Malawi. Latvia. Kenya. Iran. Indonesia. Honduras. Guyana .... Tuberculosis and Malaria: A case study of Grant SAF-304-G04-H in the Western.

  13. Modulation of reactive oxygen species production alters responses of lung inflammatory cells to endotoxin

    Czech Academy of Sciences Publication Activity Database

    Krejčová, Daniela; Konopka, Roman; Lojek, Antonín; Číž, Milan; Kubala, Lukáš

    2006-01-01

    Roč. 40, č. 1 (2006), S112-S112 ISSN 1071-5762 R&D Projects: GA ČR(CZ) GA524/06/1197 Institutional research plan: CEZ:AV0Z50040507 Keywords : myeloperoxidase * inflammation * endotoxin Subject RIV: BO - Biophysics

  14. The Compensation Act 2006 and School Trips

    Science.gov (United States)

    Hunter-Jones, John

    2006-01-01

    The Compensation Act 2006 received its Royal Assent on 25 July 2006. The Act allows the courts to have regard to the social utility of "desirable activities", including school trips, in considering negligence claims. The article reviews the law of negligence as it affects teachers of the very young and considers the possible impact of…

  15. Brain and behaviour in children with 22q11.2 deletion syndrome: a volumetric and voxel-based morphometry MRI study

    NARCIS (Netherlands)

    Campbell, Linda E.; Daly, Eileen; Toal, Fiona; Stevens, Angela; Azuma, Rayna; Catani, Marco; Ng, Virginia; van Amelsvoort, Therese; Chitnis, Xavier; Cutter, William; Murphy, Declan G. M.; Murphy, Kieran C.

    2006-01-01

    In people with velo-cardio-facial syndrome [or 22q11.2 deletion syndrome (22qDS)], a single interstitial deletion of chromosome 22q11.2 causes a wide spectrum of cognitive deficits ranging from global learning difficulties to specific cognitive deficits. People with 22qDS are also at high risk of

  16. 2006 LANL Radionuclide Air Emissions Report

    Energy Technology Data Exchange (ETDEWEB)

    David P. Fuehne

    2007-06-30

    This report describes the impacts from emissions of radionuclides at Los Alamos National Laboratory (LANL) for calendar year 2006. This report fulfills the requirements established by the Radionuclide National Emissions Standards for Hazardous Air Pollutants (Rad-NESHAP). This report is prepared by LANL's Rad-NESHAP compliance team, part of the Environmental Protection Division. The information in this report is required under the Clean Air Act and is being reported to the U.S. Environmental Protection Agency (EPA). The highest effective dose equivalent (EDE) to an off-site member of the public was calculated using procedures specified by the EPA and described in this report. LANL's EDE was 0.47 mrem for 2006. The annual limit established by the EPA is 10 mrem per year. During calendar year 2006, LANL continuously monitored radionuclide emissions at 28 release points, or stacks. The Laboratory estimates emissions from an additional 58 release points using radionuclide usage source terms. Also, LANL uses a network of air samplers around the Laboratory perimeter to monitor ambient airborne levels of radionuclides. To provide data for dispersion modeling and dose assessment, LANL maintains and operates meteorological monitoring systems. From these measurement systems, a comprehensive evaluation is conducted to calculate the EDE for the Laboratory. The EDE is evaluated as any member of the public at any off-site location where there is a residence, school, business, or office. In 2006, this location was the Los Alamos Airport Terminal. The majority of this dose is due to ambient air sampling of plutonium emitted from 2006 clean-up activities at an environmental restoration site (73-002-99; ash pile). Doses reported to the EPA for the past 10 years are shown in Table E1.

  17. Decision trees and decision committee applied to star/galaxy separation problem

    Science.gov (United States)

    Vasconcellos, Eduardo Charles

    Vasconcellos et al [1] study the efficiency of 13 diferente decision tree algorithms applied to photometric data in the Sloan Digital Sky Digital Survey Data Release Seven (SDSS-DR7) to perform star/galaxy separation. Each algorithm is defined by a set fo parameters which, when varied, produce diferente final classifications trees. In that work we extensively explore the parameter space of each algorithm, using the set of 884,126 SDSS objects with spectroscopic data as the training set. We find that Functional Tree algorithm (FT) yields the best results by the mean completeness function (galaxy true positive rate) in two magnitude intervals:14=19 (82.1%). We compare FT classification to the SDSS parametric, 2DPHOT and Ball et al (2006) classifications. At the faintest magnitudes (r > 19), our classifier is the only one that maintains high completeness (>80%) while simultaneously achieving low contamination ( 2.5%). We also examine the SDSS parametric classifier (psfMag - modelMag) to see if the dividing line between stars and galaxies can be adjusted to improve the classifier. We find that currently stars in close pairs are often misclassified as galaxies, and suggest a new cut to improve the classifier. Finally, we apply our FT classifier to separate stars from galaxies in the full set of 69,545,326 SDSS photometric objects in the magnitude range 14 train six FT classifiers with random selected objects from the same 884,126 SDSS-DR7 objects with spectroscopic data that we use before. Both, the decision commitee and our previous single FT classifier will be applied to the new ojects from SDSS data releses eight, nine and ten. Finally we will compare peformances of both methods in this new data set. [1] Vasconcellos, E. C.; de Carvalho, R. R.; Gal, R. R.; LaBarbera, F. L.; Capelato, H. V.; Fraga Campos Velho, H.; Trevisan, M.; Ruiz, R. S. R.. Decision Tree Classifiers for Star/Galaxy Separation. The Astronomical Journal, Volume 141, Issue 6, 2011.

  18. Tantsuaasta 2006 / Nele Suisalu

    Index Scriptorium Estoniae

    Suisalu, Nele

    2007-01-01

    2006. aasta kolmest tantsusündmusest Kanuti Gildi saalis : Made in Estonia maraton (25. märtsil), Räägime tantsust (25.-27. apr.) ja tantsu loomingulisest laboratooriumist Colina (Collaboration in Arts) Lab Tallinn (22. juuli - 4. aug)

  19. A large de novo distal 16p11.2 deletion in a patient with normal intelligence: Evidence for a neuropsychological phenotype

    NARCIS (Netherlands)

    Egger, J.I.M.; Verhoeven, W.M.A.; Verbeeck, W.J.C.; Leeuw, N. de

    2014-01-01

    Objective: The 16p11.2 microdeletion syndrome is characterized by a wide range of phenotypic expressions and is often associated with developmental delay, symptoms from the autism spectrum, epilepsy, congenital anomalies and obesity. Usually, these phenotypes are related to a proximal 16p11.2

  20. Neuropsychological phenotype of a patient with a de novo 970 kb interstitial deletion in the distal 16p11.2 region

    NARCIS (Netherlands)

    Egger, J.I.; Verhoeven, W.M.A.; Verbeeck, W.J.C.; Leeuw, N. de

    2014-01-01

    The 16p11.2 microdeletion syndrome is characterized by a wide range of phenotypic expressions and is frequently associated with developmental delay, symptoms from the autism spectrum, epilepsy, congenital anomalies, and obesity. These phenotypes are often related to a proximal 16p11.2 deletion of

  1. Neuropsychological phenotype of a patient with a de novo 970 kb interstitial deletion in the distal 16p11.2 region

    NARCIS (Netherlands)

    J.I.M. Egger (Jos); W.M.A. Verhoeven (Wim); W. Verbeeck (Wim); N. de Leeuw (Nicole)

    2014-01-01

    textabstractThe 16p11.2 microdeletion syndrome is characterized by a wide range of phenotypic expressions and is frequently associated with developmental delay, symptoms from the autism spectrum, epilepsy, congenital anomalies, and obesity. These phenotypes are often related to a proximal 16p11.2

  2. Confirmation that the conotruncal anomaly face syndrome is associated with a deletion within 22q11.2

    Energy Technology Data Exchange (ETDEWEB)

    Matsuoka, Rumiko; Takao, Atsuyoshi; Kimura, Misa; Kondo, Chisato; Ando, Masahiko; Momma, Kazuo; Imamura, Shin-ichiro [Heart Institute, Tokyo (Japan); Joh-o, Kunitaka [Welfare Pension Hospital, Kyushu (Japan); Ikeda, Kazuo [Sapporo Medical Univ. (Japan); Nishibatake, Makoto [Kagoshima Seikyo Hospital (Japan)

    1994-11-15

    The so-called {open_quotes}conotruncal anomaly face syndrome{close_quotes} (CTAFS) is characterized by a peculiar facial appearance associated with congenital heart disease (CHD), especially cardiac outflow tract defects such as tetralogy of Fallot (TOF), double outlet ring ventricle (DORV), and truncus arteriosus (TAC). CTAFS and the DiGeorge anomaly (DGA) have many similar phenotypic characteristics, suggesting that they share a common cause. In many cases DGA is known to be associated with monosomy for a region of chromosome 22q11.2. Fifty CTAFS patients and 10 DGA patients, 11 parents couples and 10 mothers of CTAFS patients, and 3 parents couples and 2 mothers of DGA patients were examined by fluorescent in situ hybridization (FISH) using the N25 (D22S75) DGCR probe (Oncor). Monosomy for a region of 22q11.2 was found in 42 CTAFS, 9 DGA, 4 mothers, and 1 father who had CTAF without CHD. The remaining 8 CTAFS patients, 1 DGA patient and 1 mother who had questionable CTAF without CHD, showed no such chromosome abnormality. For the control, 60 patients who had CHD without CTAF or other know malformation syndromes were examined and had no deletion of 22q11.2. Therefore, we conclude that CTAFS is a part of the CATCH 22 syndrome; cardiac defects, abnormal faces, thymic hypoplasia, cleft palate, and hypocalcemia (CATCH) resulting from 22q11.2 deletions. 20 refs., 3 figs., 2 tabs.

  3. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.

    Directory of Open Access Journals (Sweden)

    Anthony R Isles

    2016-05-01

    Full Text Available Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS region have been associated with developmental delay (DD, autism spectrum disorder (ASD and schizophrenia (SZ. Due to presence of imprinted genes within the region, the parental origin of these duplications may be key to the pathogenicity. Duplications of maternal origin are associated with disease, whereas the pathogenicity of paternal ones is unclear. To clarify the role of maternal and paternal duplications, we conducted the largest and most detailed study to date of parental origin of 15q11.2-q13.3 interstitial duplications in DD, ASD and SZ cohorts. We show, for the first time, that paternal duplications lead to an increased risk of developing DD/ASD/multiple congenital anomalies (MCA, but do not appear to increase risk for SZ. The importance of the epigenetic status of 15q11.2-q13.3 duplications was further underlined by analysis of a number of families, in which the duplication was paternally derived in the mother, who was unaffected, whereas her offspring, who inherited a maternally derived duplication, suffered from psychotic illness. Interestingly, the most consistent clinical characteristics of SZ patients with 15q11.2-q13.3 duplications were learning or developmental problems, found in 76% of carriers. Despite their lower pathogenicity, paternal duplications are less frequent in the general population with a general population prevalence of 0.0033% compared to 0.0069% for maternal duplications. This may be due to lower fecundity of male carriers and differential survival of embryos, something echoed in the findings that both types of duplications are de novo in just over 50% of cases. Isodicentric chromosome 15 (idic15 or interstitial triplications were not observed in SZ patients or in controls. Overall, this study refines the distinct roles of maternal and paternal interstitial duplications at 15q11.2-q13.3, underlining the critical importance of

  4. Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders

    Science.gov (United States)

    Isles, Anthony R.; Ingason, Andrés; Lowther, Chelsea; Gawlick, Micha; Stöber, Gerald; Potter, Harry; Georgieva, Lyudmila; Pizzo, Lucilla; Ozaki, Norio; Kushima, Itaru; Ikeda, Masashi; Iwata, Nakao; Levinson, Douglas F.; Gejman, Pablo V.; Shi, Jianxin; Sanders, Alan R.; Duan, Jubao; Sisodiya, Sanjay; Costain, Gregory; Degenhardt, Franziska; Giegling, Ina; Rujescu, Dan; Hreidarsson, Stefan J.; Saemundsen, Evald; Ahn, Joo Wook; Ogilvie, Caroline; Stefansson, Hreinn; Stefansson, Kari; O’Donovan, Michael C.; Owen, Michael J.; Bassett, Anne; Kirov, George

    2016-01-01

    Duplications at 15q11.2-q13.3 overlapping the Prader-Willi/Angelman syndrome (PWS/AS) region have been associated with developmental delay (DD), autism spectrum disorder (ASD) and schizophrenia (SZ). Due to presence of imprinted genes within the region, the parental origin of these duplications may be key to the pathogenicity. Duplications of maternal origin are associated with disease, whereas the pathogenicity of paternal ones is unclear. To clarify the role of maternal and paternal duplications, we conducted the largest and most detailed study to date of parental origin of 15q11.2-q13.3 interstitial duplications in DD, ASD and SZ cohorts. We show, for the first time, that paternal duplications lead to an increased risk of developing DD/ASD/multiple congenital anomalies (MCA), but do not appear to increase risk for SZ. The importance of the epigenetic status of 15q11.2-q13.3 duplications was further underlined by analysis of a number of families, in which the duplication was paternally derived in the mother, who was unaffected, whereas her offspring, who inherited a maternally derived duplication, suffered from psychotic illness. Interestingly, the most consistent clinical characteristics of SZ patients with 15q11.2-q13.3 duplications were learning or developmental problems, found in 76% of carriers. Despite their lower pathogenicity, paternal duplications are less frequent in the general population with a general population prevalence of 0.0033% compared to 0.0069% for maternal duplications. This may be due to lower fecundity of male carriers and differential survival of embryos, something echoed in the findings that both types of duplications are de novo in just over 50% of cases. Isodicentric chromosome 15 (idic15) or interstitial triplications were not observed in SZ patients or in controls. Overall, this study refines the distinct roles of maternal and paternal interstitial duplications at 15q11.2-q13.3, underlining the critical importance of maternally

  5. Economic Decisions in Farm Animal Health

    DEFF Research Database (Denmark)

    Ettema, Jehan Frans; Kudahl, Anne Braad; Sørensen, Jan Tind

    Animal health economics deals with quantifying the economic effects of animal disease, decision support tools in animal health management and further analysis of the management's impact at animal, herd or national level. Scientists from The Netherlands, France and Sweden have since 1988 organised...... informal workshops to exchange their knowledge and expertise in this field of science. This report contains the summary of the presentations given by 12 PhD students and 2 senior scientists of the Animal Health Economics workshops which was held on the 9th and 10th of November, 2006 at the Research Centre...... Foulum in Denmark. Different disciplines and approaches within Animal Health Economics are dealt with by the different scientists and the report contains a variety of novel results and projects. The resulting discussion is summarized in the report....

  6. 50 CFR 86.112 - What are the advantages of doing a survey?

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false What are the advantages of doing a survey... INFRASTRUCTURE GRANT (BIG) PROGRAM How States Will Complete Access Needs Surveys § 86.112 What are the advantages of doing a survey? Surveys provide the information necessary to fully understand the needs of boaters...

  7. The wastes management: possible scenario for 2006

    International Nuclear Information System (INIS)

    Capdevila, J.M.

    2003-03-01

    This document gathers the slides presented by J.M. Capdevila at the Seminar DEN/SAC the 13 mars 2003. They deal with the law of the 30 december 1991 concerning the radioactive wastes management, the research and development programs begun at the Cea and the short dated projects (2006), the forecast of the situation after 2006. (A.L.B.)

  8. Interesting coin finds of 2006 / Mauri Kiudsoo

    Index Scriptorium Estoniae

    Kiudsoo, Mauri, 1973-

    2007-01-01

    2006. aasta huvitavamatest mündileidudest. Lisaks arheoloogilistelt kaevamistelt saadud vermingutele omandati 2006. aastal kolm mündiaaret : Alansi aare Harjumaalt, ligi poolsada araabia hõbemünti sisaldav aare Tartust ning tänu politsei kaasabile jõudsid Eestisse tagasi Ubina hõbeaadre kaevamistelt varastatud hõbemündid. Eestist leitud rooma müntidest

  9. Characterization of ultra-thin TiO2 films grown on Mo(112)

    International Nuclear Information System (INIS)

    Kumar, D.; Chen, M.S.; Goodman, D.W.

    2006-01-01

    Ultra-thin TiO 2 films were grown on a Mo(112) substrate by stepwise vapor depositing of Ti onto the sample surface followed by oxidation at 850 K. X-ray photoelectron spectroscopy showed that the Ti 2p peak position shifts from lower to higher binding energy with an increase in the Ti coverage from sub- to multilayer. The Ti 2p peak of a TiO 2 film with more than a monolayer coverage can be resolved into two peaks, one at 458.1 eV corresponding to the first layer, where Ti atoms bind to the substrate Mo atoms through Ti-O-Mo linkages, and a second feature at 458.8 eV corresponding to multilayer TiO 2 where the Ti atoms are connected via Ti-O-Ti linkages. Based on these assignments, the single Ti 2p 3/2 peak at 455.75 eV observed for the Mo(112)-(8 x 2)-TiO x monolayer film can be assigned to Ti 3+ , consistent with our previous results obtained with high-resolution electron energy loss spectroscopy

  10. C1-2 vertebral anomalies in 22q11.2 microdeletion syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Konen, Osnat; Armstrong, Derek; Padfield, Nancy; Blaser, Susan [Hospital for Sick Children, Diagnostic Imaging, Toronto (Canada); Clarke, Howard [Hospital for Sick Children, Plastic Surgery, Toronto (Canada); Weksberg, Rosanna [Hospital for Sick Children, Clinical and Metabolic Genetics, Toronto (Canada)

    2008-07-15

    Chromosome 22q11.2 microdeletion syndrome (22q11DS) is characterized by cleft palate, cardiac anomalies, characteristic facies, high prevalence of skeletal anomalies and learning disability. To evaluate the prevalence of craniovertebral junction anomalies in children with 22q11DS and compare these findings to those in nonsyndromic children with velopharyngeal insufficiency (VPI). Sequential CT scans performed for presurgical carotid assessment in 76 children (45 children positive for chromosome 22q11.2 deletion and 31 negative for the deletion) with VPI were retrospectively evaluated for assessment of C1-2 anomalies. C1-2 vertebral anomalies, specifically midline C1 defects, uptilted or upswept posterior elements of C2 and fusions of C2-3, were nearly universal in our cohort of 22q11DS patients with VPI. They were strikingly absent in the majority of non-22q11DS patients with VPI. C1-2 vertebral anomalies, particularly those listed above, are important radiographic markers for 22q11DS. (orig.)

  11. C1-2 vertebral anomalies in 22q11.2 microdeletion syndrome

    International Nuclear Information System (INIS)

    Konen, Osnat; Armstrong, Derek; Padfield, Nancy; Blaser, Susan; Clarke, Howard; Weksberg, Rosanna

    2008-01-01

    Chromosome 22q11.2 microdeletion syndrome (22q11DS) is characterized by cleft palate, cardiac anomalies, characteristic facies, high prevalence of skeletal anomalies and learning disability. To evaluate the prevalence of craniovertebral junction anomalies in children with 22q11DS and compare these findings to those in nonsyndromic children with velopharyngeal insufficiency (VPI). Sequential CT scans performed for presurgical carotid assessment in 76 children (45 children positive for chromosome 22q11.2 deletion and 31 negative for the deletion) with VPI were retrospectively evaluated for assessment of C1-2 anomalies. C1-2 vertebral anomalies, specifically midline C1 defects, uptilted or upswept posterior elements of C2 and fusions of C2-3, were nearly universal in our cohort of 22q11DS patients with VPI. They were strikingly absent in the majority of non-22q11DS patients with VPI. C1-2 vertebral anomalies, particularly those listed above, are important radiographic markers for 22q11DS. (orig.)

  12. Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome

    DEFF Research Database (Denmark)

    Starnawska, A; Hansen, C S; Sparsø, T

    2017-01-01

    Individuals with 22q11.2 deletion syndrome (DS) have an increased risk of comorbid mental disorders including schizophrenia, attention deficit hyperactivity disorder, depression, as well as intellectual disability. Although most 22q11.2 deletion carriers have the long 3-Mb form of the hemizygous...... with mental disorder later in life. DNA methylation was measured genome-wide from neonatal dried blood spots in a cohort of 164 individuals with 22q11.2DS, including 48 individuals diagnosed with a psychiatric disorder. Among several CpG sites with P-value...-98), in NOSIP (P-value=5.12 × 10-8) with disorders of psychological development (F80-89) and in SEMA4B (P-value=4.02 × 10-7) with schizophrenia spectrum disorders (F20-29). In conclusion, our study suggests an association of DNA methylation differences at birth with development of mental disorder later in life...

  13. FY 2006 Supplement to the President`s Budget

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — This Supplement to the Presidents Budget for Fiscal Year 2006 offers a brief technical outline of the 2006 budget request for the Networking and Information...

  14. What practice can learn from theory: The potential impact of disposition decision factors on organisational performance

    Directory of Open Access Journals (Sweden)

    Amanda Badenhorst

    2018-02-01

    Full Text Available Background: Effective disposition decisions can lead to a number of value-adding benefits including economic, environmental and marketing benefits. Despite this, many organisations are not aware of the importance of disposition decisions and the impact they can have on organisational performance. Objectives: The aim of this study was to demonstrate the potential impact of disposition decision factors on organisational performance. Method: This study made use of a qualitative content analysis method on previously published scientific articles on reverse logistics. The sample included 67 published scientific articles between 2006 and 2016. ATLAS.ti software was used to assist with the data analysis process. Findings: The findings showed a number of factors for disposition decision-making resulting in a number of value-adding benefits, which can improve organisational performance. From the findings, a conceptual framework was developed linking the disposition decision factors with the value-adding benefits and areas of organisational performance improvements. Conclusion: The framework developed in this article contributes to new insights and can help organisations to identify different performance improvement areas associated with certain disposition decision factors.

  15. Choosing between 7-, 10- and 13-valent pneumococcal conjugate vaccines in childhood: a review of economic evaluations (2006-2014).

    Science.gov (United States)

    Wu, David Bin-Chia; Chaiyakunapruk, Nathorn; Chong, Huey-Yi; Beutels, Philippe

    2015-03-30

    Seven-valent pneumococcal conjugate vaccines (PCV7) have been used in children for more than a decade. Given the observed increase in disease caused by pneumococcal serotypes not covered by PCV7, an increasing number of countries are switching from 7-valent to 10- and 13-valent PCVs ("PCV10" and "PCV13"). Economic evaluations are important tools to inform decisions and price negotiations to make such a switch. This review aims to provide a critical assessment of economic evaluations involving PCV10 or PCV13, published since 2006. We searched Scopus, ISI Web of Science (SCI and SSCI) and Pubmed to retrieve, select and review relevant studies, which were archived between 1st January 2006 and 31st January 2014. The review protocol involved standard extraction of assumptions, methods, results and sponsorships from the original studies. Sixty-three economic evaluations on PCVs published since January 2006 were identified. About half of these evaluated PCV10 and/or PCV13, the subject of this review. At current prices, both PCV13 and PCV10 were likely judged preferable to PCV7. However, the combined uncertainty related to price differences, burden of disease, vaccine effectiveness, herd and serotype replacement effects determine the preference base for either PCV10 or PCV13. The pivotal assumptions and results of these analyses also depended on which manufacturer sponsored the study. A more thorough exploration of uncertainty should be made in future analyses on this subject, as we lack understanding to adequately model herd and serotype replacement effects to reliably predict the population impact of PCVs. The introduction of further improved PCVs in an environment of evolving antibiotic resistance and under the continuing influence of previous PCVs implies that the complexity and data requirements for relevant analyses will further increase. Decision makers using these analyses should not just rely on an analysis from a single manufacturer. Copyright © 2015 Elsevier

  16. 2006 Israeli-Hezbollah War: a Fight of Operational Synchronization

    Science.gov (United States)

    2016-05-13

    13. 2 Stephen Biddle and Jeffrey A. Friedman, The 2006 Lebanon Campaign and the Future of Warfare (Carlisle: Strategic Studies Institute, 2008...fighters.” 18 18 Stephen Biddle and Jeffrey A. Friedman, The 2006 Lebanon Campaign and the...Stephen Biddle and Jeffrey A. Friedman, The 2006 Lebanon Campaign and the Future of Warfare, 32. 28 Ibid., 32. 29 Ibid., 32. 30 Matt M. Matthews, “Hard

  17. Ethnic differences in informed decision-making about prenatal screening for Down's syndrome.

    Science.gov (United States)

    Fransen, Mirjam P; Essink-Bot, Marie-Louise; Vogel, Ineke; Mackenbach, Johan P; Steegers, Eric A P; Wildschut, Hajo I J

    2010-03-01

    The aim of this study was to assess ethnic variations in informed decision-making about prenatal screening for Down's syndrome and to examine the contribution of background and decision-making variables. Pregnant women of Dutch, Turkish and Surinamese origin were recruited between 2006 and 2008 from community midwifery or obstetrical practices in The Netherlands. Each woman was personally interviewed 3 weeks (mean) after booking for prenatal care. Knowledge, attitude and participation in prenatal screening were assessed following the 'Multidimensional Measure of Informed Choice' that has been developed and applied in the UK. In total, 71% of the Dutch women were classified as informed decision-makers, compared with 5% of the Turkish and 26% of the Surinamese women. Differences between Surinamese and Dutch women could largely be attributed to differences in educational level and age. Differences between Dutch and Turkish women could mainly be attributed to differences in language skills and gender emancipation. Women from ethnic minority groups less often made an informed decision whether or not to participate in prenatal screening. Interventions to decrease these ethnic differences should first of all be aimed at overcoming language barriers and increasing comprehension among women with a low education level. To further develop diversity-sensitive strategies for counselling, it should be investigated how women from different ethnic backgrounds value informed decision-making in prenatal screening, what decision-relevant knowledge they need and what they take into account when considering participation in prenatal screening.

  18. The discovery of elements 107 to 112

    Directory of Open Access Journals (Sweden)

    Hofmann Sigurd

    2016-01-01

    Full Text Available In the 1960s, theoretical concepts prepared the path to nuclear matter with proton and neutron numbers far beyond the nuclei known at that time. The new laboratory GSI was founded for research on reactions with heavy ions, in particular those for production of the predicted super-heavy nuclei. In this contribution it is presented how the interaction between experiment and theory resulted in a continuous improvement of the experimental set-ups on the one hand, and of the knowledge of the processes during the nuclear reaction and of the properties of the produced nuclei on the other hand. In the course of this work six new elements from 107 to 112 were produced and identified. An overview of the present status of experimental results and a comparison with theoretical interpretations is given.

  19. Densitometria clínica: posições oficiais 2006 Clinical densitometry: official positions 2006

    Directory of Open Access Journals (Sweden)

    Cristiano A. F. Zerbini

    2007-02-01

    Full Text Available Descrevemos as posições oficiais da Sociedade Brasileira de Densitometria Clínica (SBDens para a realização e o relato do exame de densitometria óssea. Essas posições foram obtidas por consenso em encontro realizado em São Paulo no ano de 2006. A SBDens contou com o apoio de várias sociedades científicas descritas no texto.We describe the official positions of the Brazilian Society for Clinical Densitometry (SBDens for the performance and report of the bone mineral density testing. These positions were obtained by consensus in a meeting at São Paulo in 2006. SBDens positions were supported by other scientific societies described in the text.

  20. The benefit of enterprise ontology in identifying business components

    OpenAIRE

    Albani, Antonia

    2006-01-01

    The benefit of enterprise ontology in identifying business components / A. Albani, J. Dietz. - In: Artificial intelligence in theory and practice : IFIP 19th World Computer Congress ; TC 12: IFIP AI 2006 Stream, August 21-24, 2006, Santiago, Chile / ed. by Max Bramer. - New York : Springer, 2006. - S. 1-12. - (IFIP ; 217)