[Comparison of immune response after oral and intranasal immunization with recombinant Lactobacillus casei expressing ETEC F41].

Science.gov (United States)

Liu, Jiankui; Wei, Chunhua; Hou, Xilin; Wang, Guihua; Yu, Liyun

2009-04-01

In order to represent a promising strategy for mucosal vaccination, oral or intranasal immunization of Specific Pathogen Free (SPF) BALB/c mice were performed. The mucosal immunity, systemic immune and protective immune responses were compared after immunization with the recombinant Lactobacillus casei (L. casei) harboring enterotoxigenic Escherichia coli (ETEC) F41. The recombinant fusion proteins were detected by Western blot. Surface localization of the fusion protein was verified by immunofluorescence microscopy and flow cytometry. Six-week-old female SPF BALB/c mice (160 heads) were divided into 4 groups for immunization and control. Oral and intranasal immunization of mice was performed with the recombinant strain L. casei harboring pLA-F41 or pLA. For oral immunization, the mice were inoculated daily on days 0 to 4, 7 to 11, 21 to 25, and 49 to 53. A lighter schedule was used for nasal immunization (days 0 to 2, 7 to 9, 21 and 49). Specific anti-F41 IgG antibody in the serum and specific anti-F41 secret immunoglobulin A (sIgA) antibody in the lung, intestines, vagina fluid and feces of mice were detected by indirect ELISA. The mice orally or intranasally immunized with pLA-F41/L. casei and pLA/IL. casei were challenged with standard-type ETEC F41 (C83919) (2 x 10(3) LD50). Mice immunized with pLA-F41/L. casei could produce remarkable anti-F41 antibody level. More than 90% survived in oral immunization group whereas more than 85% survived in intranasal immunization group after challenged with C83919, all dead in the control group. Ninety percent of the pups survived in oral immunization group whereas 80% survived in intranasal immunization group after challenged with C83919, but only a 5% survival rate for pups that were either immunized with a control pLA vector or unimmunized. Oral or intranasal immunization with recombinant L. casei displaying ETEC F41 antigens on the surface induced effective and similar systemic and mucosal immune responses against the

RESPONS ANTIBODI ANTI ETEC K99 PADA INDUK SAPI BUNTING SETELAH PEMBERIAN VAKSIN ESCHERICHIA COLI POLIVALEN

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Anita Esfandiari

2014-08-01

Full Text Available The objective of this experiment was to detect antibody (IgG against enterotoxigenic Escherichia coli (ETECK99 in the blood of cows vaccinated by Escherichia coli polyvalent vaccine. Eight dry cows were injectedsubcutaneously by polyvalent Escherichia coli twice prior to parturition. Before vaccinated, the cows were givenimmunomodulator orally for 3 days. Blood samples were drawn from coccigeal vein prior to the 1st vaccination,two week following the 1st vaccination and at 1, 2, and 4 weeks after the 2nd vaccination. Blood samples wereanalyzed for IgG and ETEC K99 using indirect Enzyme Linked Immunosorbent Assay (ELISA assay. Results of theexperiment indicated that absorbance values of all vaccinated cows before the first vaccination until third weekfollowing the 2nd vaccination were below cut off values. The absorbance values then increased and were above cutoff values at fourth week following the 2nd vaccination. In conclusion, antibody against ETEC K99, were detected inthe blood of cows, fourth week following the 2nd vaccination.

Effect of pea and faba bean fractions on net fluid absorption in ETEC-infected small intestinal segements of weaned piglets

NARCIS (Netherlands)

Meulen, van der J.; Jansman, A.J.M.

2010-01-01

After weaning piglets frequently have diarrhoea associated with an enterotoxigenic Escherichia coli (ETEC) infection. Alternative plant protein sources such as peas, faba beans and lupins may contribute in preventing gastrointestinal problems. In the small intestinal segment perfusion model, the

Vaccines for viral and bacterial pathogens causing acute gastroenteritis: Part II: Vaccines for Shigella, Salmonella, enterotoxigenic E. coli (ETEC) enterohemorragic E. coli (EHEC) and Campylobacter jejuni

Science.gov (United States)

O’Ryan, Miguel; Vidal, Roberto; del Canto, Felipe; Carlos Salazar, Juan; Montero, David

2015-01-01

In Part II we discuss the following bacterial pathogens: Shigella, Salmonella (non-typhoidal), diarrheogenic E. coli (enterotoxigenic and enterohemorragic) and Campylobacter jejuni. In contrast to the enteric viruses and Vibrio cholerae discussed in Part I of this series, for the bacterial pathogens described here there is only one licensed vaccine, developed primarily for Vibrio cholerae and which provides moderate protection against enterotoxigenic E. coli (ETEC) (Dukoral®), as well as a few additional candidates in advanced stages of development for ETEC and one candidate for Shigella spp. Numerous vaccine candidates in earlier stages of development are discussed. PMID:25715096

Comparison of antimicrobial resistance in E. coli isolated from rectal and floor samples in pens with diarrhoeic nursery pigs in Denmark

DEFF Research Database (Denmark)

Weber, Nicolai Rosager; Nielsen, Jens Peter; Jorsal, Sven Erik Lind

2017-01-01

and classified as ETEC when genes for adhesin factors and enterotoxins were detected. Minimum inhibitory concentrations of 13 antimicrobial agents were determined by the broth micro dilution method. Isolates were classified as resistant based on clinical breakpoints. Results. Based on logistic regression models......%: 2.87-18.10). The odds of an isolate being resistant were significantly higher in ETEC isolates compared to Non-ETEC isolates for ampicillin (p trimethoprim (p..., sulphamethoxazole, tetracycline and trimethoprim. Conclusions. We found that ETEC isolates were more resistant than Non-ETEC isolates. Furthermore, this study indicates that resistance testing of ETEC isolates from pen floor samples can be used as a convenient sampling method for resistance testing...

Development and preclinical evaluation of safety and immunogenicity of an oral ETEC vaccine containing inactivated E. coli bacteria overexpressing colonization factors CFA/I, CS3, CS5 and CS6 combined with a hybrid LT/CT B subunit antigen, administered alone and together with dmLT adjuvant.

Science.gov (United States)

Holmgren, J; Bourgeois, L; Carlin, N; Clements, J; Gustafsson, B; Lundgren, A; Nygren, E; Tobias, J; Walker, R; Svennerholm, A-M

2013-05-07

A first-generation oral inactivated whole-cell enterotoxigenic Escherichia coli (ETEC) vaccine, comprising formalin-killed ETEC bacteria expressing different colonization factor (CF) antigens combined with cholera toxin B subunit (CTB), when tested in phase III studies did not significantly reduce overall (generally mild) ETEC diarrhea in travelers or children although it reduced more severe ETEC diarrhea in travelers by almost 80%. We have now developed a novel more immunogenic ETEC vaccine based on recombinant non-toxigenic E. coli strains engineered to express increased amounts of CF antigens, including CS6 as well as an ETEC-based B subunit protein (LCTBA), and the optional combination with a nontoxic double-mutant heat-labile toxin (LT) molecule (dmLT) as an adjuvant. Two test vaccines were prepared under GMP: (1) A prototype E. coli CFA/I-only formalin-killed whole-cell+LCTBA vaccine, and (2) A "complete" inactivated multivalent ETEC-CF (CFA/I, CS3, CS5 and CS6 antigens) whole-cell+LCTBA vaccine. These vaccines, when given intragastrically alone or together with dmLT in mice, were well tolerated and induced strong intestinal-mucosal IgA antibody responses as well as serum IgG and IgA responses to each of the vaccine CF antigens as well as to LT B subunit (LTB). Both mucosal and serum responses were further enhanced (adjuvanted) when the vaccines were co-administered with dmLT. We conclude that the new multivalent oral ETEC vaccine, both alone and especially in combination with the dmLT adjuvant, shows great promise for further testing in humans. Copyright © 2013 Elsevier Ltd. All rights reserved.

Expression of colonization factor CS5 of enterotoxigenic Escherichia coli (ETEC is enhanced in vivo and by the bile component Na glycocholate hydrate.

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Matilda Nicklasson

Full Text Available Enterotoxigenic Escherichia coli (ETEC is an important cause of acute watery diarrhoea in developing countries. Colonization factors (CFs on the bacterial surface mediate adhesion to the small intestinal epithelium. Two of the most common CFs worldwide are coli surface antigens 5 and 6 (CS5, CS6. In this study we investigated the expression of CS5 and CS6 in vivo, and the effects of bile and sodium bicarbonate, present in the human gut, on the expression of CS5. Five CS5+CS6 ETEC isolates from adult Bangladeshi patients with acute diarrhoea were studied. The level of transcription from the CS5 operon was approximately 100-fold higher than from the CS6 operon in ETEC bacteria recovered directly from diarrhoeal stool without sub-culturing (in vivo. The glyco-conjugated primary bile salt sodium glycocholate hydrate (NaGCH induced phenotypic expression of CS5 in a dose-dependent manner and caused a 100-fold up-regulation of CS5 mRNA levels; this is the first description of NaGCH as an enteropathogenic virulence inducer. The relative transcription levels from the CS5 and CS6 operons in the presence of bile or NaGCH in vitro were similar to those in vivo. Another bile salt, sodium deoxycholate (NaDC, previously reported to induce enteropathogenic virulence, also induced expression of CS5, whereas sodium bicarbonate did not.

An outbreak of enterotoxigenic Escherichia coli (ETEC) infection in Norway, 2012: a reminder to consider uncommon pathogens in outbreaks involving imported products.

Science.gov (United States)

MacDonald, E; Møller, K E; Wester, A L; Dahle, U R; Hermansen, N O; Jenum, P A; Thoresen, L; Vold, L

2015-02-01

We investigated an outbreak of gastroenteritis following a Christmas buffet served on 4-9 December 2012 to ~1300 hotel guests. More than 300 people were reported ill in initial interviews with hotel guests. To identify possible sources of infection we conducted a cohort investigation through which we identified 214 probable cases. Illness was associated with consumption of scrambled eggs (odds ratio 9·07, 95% confidence interval 5·20-15·84). Imported chives added fresh to the scrambled eggs were the suspected source of the outbreak but were unavailable for testing. Enterotoxigenic Escherichia coli (ETEC) infection was eventually confirmed in 40 hotel guests. This outbreak reinforces that ETEC should be considered in non-endemic countries when the clinical picture is consistent and common gastrointestinal pathogens are not found. Following this outbreak, the Norwegian Food Safety Authority recommended that imported fresh herbs should be heat-treated before use in commercial kitchens.

Genetic fusions of a CFA/I/II/IV MEFA (multiepitope fusion antigen) and a toxoid fusion of heat-stable toxin (STa) and heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC) retain broad anti-CFA and antitoxin antigenicity.

Science.gov (United States)

Ruan, Xiaosai; Sack, David A; Zhang, Weiping

2015-01-01

Immunological heterogeneity has long been the major challenge in developing broadly effective vaccines to protect humans and animals against bacterial and viral infections. Enterotoxigenic Escherichia coli (ETEC) strains, the leading bacterial cause of diarrhea in humans, express at least 23 immunologically different colonization factor antigens (CFAs) and two distinct enterotoxins [heat-labile toxin (LT) and heat-stable toxin type Ib (STa or hSTa)]. ETEC strains expressing any one or two CFAs and either toxin cause diarrhea, therefore vaccines inducing broad immunity against a majority of CFAs, if not all, and both toxins are expected to be effective against ETEC. In this study, we applied the multiepitope fusion antigen (MEFA) strategy to construct ETEC antigens and examined antigens for broad anti-CFA and antitoxin immunogenicity. CFA MEFA CFA/I/II/IV [CVI 2014, 21(2):243-9], which carried epitopes of seven CFAs [CFA/I, CFA/II (CS1, CS2, CS3), CFA/IV (CS4, CS5, CS6)] expressed by the most prevalent and virulent ETEC strains, was genetically fused to LT-STa toxoid fusion monomer 3xSTaA14Q-dmLT or 3xSTaN12S-dmLT [IAI 2014, 82(5):1823-32] for CFA/I/II/IV-STaA14Q-dmLT and CFA/I/II/IV-STaN12S-dmLT MEFAs. Mice intraperitoneally immunized with either CFA/I/II/IV-STa-toxoid-dmLT MEFA developed antibodies specific to seven CFAs and both toxins, at levels equivalent or comparable to those induced from co-administration of the CFA/I/II/IV MEFA and toxoid fusion 3xSTaN12S-dmLT. Moreover, induced antibodies showed in vitro adherence inhibition activities against ETEC or E. coli strains expressing these seven CFAs and neutralization activities against both toxins. These results indicated CFA/I/II/IV-STa-toxoid-dmLT MEFA or CFA/I/II/IV MEFA combined with 3xSTaN12S-dmLT induced broadly protective anti-CFA and antitoxin immunity, and suggested their potential application in broadly effective ETEC vaccine development. This MEFA strategy may be generally used in multivalent

Genetic fusions of a CFA/I/II/IV MEFA (multiepitope fusion antigen and a toxoid fusion of heat-stable toxin (STa and heat-labile toxin (LT of enterotoxigenic Escherichia coli (ETEC retain broad anti-CFA and antitoxin antigenicity.

Directory of Open Access Journals (Sweden)

Xiaosai Ruan

Full Text Available Immunological heterogeneity has long been the major challenge in developing broadly effective vaccines to protect humans and animals against bacterial and viral infections. Enterotoxigenic Escherichia coli (ETEC strains, the leading bacterial cause of diarrhea in humans, express at least 23 immunologically different colonization factor antigens (CFAs and two distinct enterotoxins [heat-labile toxin (LT and heat-stable toxin type Ib (STa or hSTa]. ETEC strains expressing any one or two CFAs and either toxin cause diarrhea, therefore vaccines inducing broad immunity against a majority of CFAs, if not all, and both toxins are expected to be effective against ETEC. In this study, we applied the multiepitope fusion antigen (MEFA strategy to construct ETEC antigens and examined antigens for broad anti-CFA and antitoxin immunogenicity. CFA MEFA CFA/I/II/IV [CVI 2014, 21(2:243-9], which carried epitopes of seven CFAs [CFA/I, CFA/II (CS1, CS2, CS3, CFA/IV (CS4, CS5, CS6] expressed by the most prevalent and virulent ETEC strains, was genetically fused to LT-STa toxoid fusion monomer 3xSTaA14Q-dmLT or 3xSTaN12S-dmLT [IAI 2014, 82(5:1823-32] for CFA/I/II/IV-STaA14Q-dmLT and CFA/I/II/IV-STaN12S-dmLT MEFAs. Mice intraperitoneally immunized with either CFA/I/II/IV-STa-toxoid-dmLT MEFA developed antibodies specific to seven CFAs and both toxins, at levels equivalent or comparable to those induced from co-administration of the CFA/I/II/IV MEFA and toxoid fusion 3xSTaN12S-dmLT. Moreover, induced antibodies showed in vitro adherence inhibition activities against ETEC or E. coli strains expressing these seven CFAs and neutralization activities against both toxins. These results indicated CFA/I/II/IV-STa-toxoid-dmLT MEFA or CFA/I/II/IV MEFA combined with 3xSTaN12S-dmLT induced broadly protective anti-CFA and antitoxin immunity, and suggested their potential application in broadly effective ETEC vaccine development. This MEFA strategy may be generally used in

Oral administration of a select mixture of Bacillus probiotics generates Tr1 cells in weaned F4ab/acR- pigs challenged with an F4+ ETEC/VTEC/EPEC strain.

Science.gov (United States)

Zhou, Dong; Zhu, Yao-Hong; Zhang, Wei; Wang, Meng-Ling; Fan, Wen-Yi; Song, Dan; Yang, Gui-Yan; Jensen, Bent Borg; Wang, Jiu-Feng

2015-09-17

Although breeding of F4 receptor - negative (F4R(-)) pigs may prevent post-weaning diarrhea, the underlying immunity is poorly understood. Here, various doses of a Bacillus licheniformis and Bacillus subtilis mixture (BLS-mix) were orally administered to F4ab/acR(-) pigs for 1 week before F4 (K88) - positive ETEC/VTEC/EPEC challenge. Administration of BLS-mix increased the percentage of Foxp3(-)IL-10(+) T cells but not of Foxp3(+)IL-10(+) regulatory T (Treg) cells among peripheral blood CD4(+) T cells. A low dose of BLS-mix feeding resulted in increased the expression of IL-6, TNF-α, IL-10, and the transcription factors Foxp3 and T-bet mRNAs in the jejunum. Administration of either a low or high dose BLS-mix also led to an increase in the percentage of CD4(+)Foxp3(+) Treg cells among intraepithelial lymphocytes and CD4(+)IL-10(+) T cells in the small intestinal Peyer's patches and the lamina propria of F4ab/acR(-) pigs following F4(+) ETEC/VTEC/EPEC challenge. The increased number of IL-10-producing CD4(+) T cells was attributed to an increase in the proportion of Foxp3(-)IL-10(+) Treg cells rather than Foxp3(+)IL-10(+) Treg cells. Our data indicate that oral administration of BLS-mix to newly weaned F4ab/acR(-) pigs ameliorates enteritis in an F4(+) ETEC/VTEC/EPEC model; however, induction of IL-10-producing Foxp3(-) Treg cells by BLS-mix administration cannot account for the protection of newly weaned F4ab/acR(-) pigs from F4(+) ETEC/VTEC/EPEC infection, and that excessive generation of CD4(+)IL-10(+) T cells following consumption of BLS-mix during episodes of intestinal inflammation that is caused by enteric pathogens might prohibit clearance of the pathogen. Select probiotic mixtures may allow for tailoring strategies to prevent infectious diseases.

A City Logistics Living Lab: A Methodological Approach

NARCIS (Netherlands)

Nesterova, N.; Quak, H.

2016-01-01

The field of city logistics can be characterized by its many local demonstrations and trials, that are quite often not lasting longer than the trial period. The number of demonstrations that continued and were implemented in daily practice is limited. Freight partnerships proved to be a good first

Clinical trial to evaluate safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli prototype vaccine containing CFA/I overexpressing bacteria and recombinantly produced LTB/CTB hybrid protein.

Science.gov (United States)

Lundgren, A; Leach, S; Tobias, J; Carlin, N; Gustafsson, B; Jertborn, M; Bourgeois, L; Walker, R; Holmgren, J; Svennerholm, A-M

2013-02-06

We have developed a new oral vaccine against enterotoxigenic Escherichia coli (ETEC) diarrhea containing killed recombinant E. coli bacteria expressing increased levels of ETEC colonization factors (CFs) and a recombinant protein (LCTBA), i.e. a hybrid between the binding subunits of E. coli heat labile toxin (LTB) and cholera toxin (CTB). We describe a randomized, comparator controlled, double-blind phase I trial in 60 adult Swedish volunteers of a prototype of this vaccine. The safety and immunogenicity of the prototype vaccine, containing LCTBA and an E. coli strain overexpressing the colonization factor CFA/I, was compared to a previously developed oral ETEC vaccine, consisting of CTB and inactivated wild type ETEC bacteria expressing CFA/I (reference vaccine). Groups of volunteers were given two oral doses of either the prototype or the reference vaccine; the prototype vaccine was administered at the same or a fourfold higher dosage than the reference vaccine. The prototype vaccine was found to be safe and equally well-tolerated as the reference vaccine at either dosage tested. The prototype vaccine induced mucosal IgA (fecal secretory IgA and intestine-derived IgA antibody secreting cell) responses to both LTB and CFA/I, as well as serum IgA and IgG antibody responses to LTB. Immunization with LCTBA resulted in about twofold higher mucosal and systemic IgA responses against LTB than a comparable dose of CTB. The higher dose of the prototype vaccine induced significantly higher fecal and systemic IgA responses to LTB and fecal IgA responses to CFA/I than the reference vaccine. These results demonstrate that CF over-expression and inclusion of the LCTBA hybrid protein in an oral inactivated ETEC vaccine does not change the safety profile when compared to a previous generation of such a vaccine and that the prototype vaccine induces significant dose dependent mucosal immune responses against CFA/I and LTB. Copyright © 2013 Elsevier Ltd. All rights reserved.

Randomised, double-blind, safety and efficacy of a killed oral vaccine for enterotoxigenic E. Coli diarrhoea of travellers to Guatemala and Mexico.

Science.gov (United States)

Sack, David A; Shimko, Janet; Torres, Olga; Bourgeois, August L; Francia, Domingo Sanchez; Gustafsson, Björn; Kärnell, Anders; Nyquist, Iréne; Svennerholm, Ann-Mari

2007-05-30

We tested the efficacy of a killed oral vaccine for enterotoxigenic Escherichia coli (ETEC) diarrhoea to determine if two doses of vaccine with colonization factor antigens (CF) and cholera B subunit would protect against ETEC diarrhoea of travellers. Six hundred seventy-two healthy travellers going to Mexico or Guatemala were studied in a prospective, randomised, placebo-controlled trial. The primary outcome was a vaccine preventable outcome (VPO), defined as an episode of ETEC diarrhoea with an ETEC organism producing heat labile toxin (LT) or CF homologous with the vaccine, without other known causes. The vaccine was safe and stimulated anti-heat labile toxin antibodies. There was a significant decrease in more severe VPO episodes (PE=77%, p=0.039) as defined by symptoms that interfered with daily activities or more than five loose stools in a day, although the total number of VPO events did not differ significantly in the vaccine and placebo groups. We conclude that the new oral ETEC vaccine reduces the rate of more severe episodes of traveller's diarrhoea (TD) due to VPO-ETEC, but it did not reduce the overall rate of ETEC diarrhoea or of travellers' diarrhoea due to other causes.

Towards zero emission urban logistics: Challenges and issues for implementation of electric freight vehicles in city logistics

NARCIS (Netherlands)

Quak, H.; Nesterova, N.

2014-01-01

Purpose Electric freight vehicles (EFVs) are one of the solutions to improve city logistics’ sustainability. EFVs, that are electric powered light and heavy vehicles with a number plate, have the potential to make zero emission city logistics possible within the urban area. However, although trials

Should metacognition be measured by logistic regression?

Science.gov (United States)

Rausch, Manuel; Zehetleitner, Michael

2017-03-01

Are logistic regression slopes suitable to quantify metacognitive sensitivity, i.e. the efficiency with which subjective reports differentiate between correct and incorrect task responses? We analytically show that logistic regression slopes are independent from rating criteria in one specific model of metacognition, which assumes (i) that rating decisions are based on sensory evidence generated independently of the sensory evidence used for primary task responses and (ii) that the distributions of evidence are logistic. Given a hierarchical model of metacognition, logistic regression slopes depend on rating criteria. According to all considered models, regression slopes depend on the primary task criterion. A reanalysis of previous data revealed that massive numbers of trials are required to distinguish between hierarchical and independent models with tolerable accuracy. It is argued that researchers who wish to use logistic regression as measure of metacognitive sensitivity need to control the primary task criterion and rating criteria. Copyright © 2017 Elsevier Inc. All rights reserved.

Logistic regression for dichotomized counts.

Science.gov (United States)

Preisser, John S; Das, Kalyan; Benecha, Habtamu; Stamm, John W

2016-12-01

Sometimes there is interest in a dichotomized outcome indicating whether a count variable is positive or zero. Under this scenario, the application of ordinary logistic regression may result in efficiency loss, which is quantifiable under an assumed model for the counts. In such situations, a shared-parameter hurdle model is investigated for more efficient estimation of regression parameters relating to overall effects of covariates on the dichotomous outcome, while handling count data with many zeroes. One model part provides a logistic regression containing marginal log odds ratio effects of primary interest, while an ancillary model part describes the mean count of a Poisson or negative binomial process in terms of nuisance regression parameters. Asymptotic efficiency of the logistic model parameter estimators of the two-part models is evaluated with respect to ordinary logistic regression. Simulations are used to assess the properties of the models with respect to power and Type I error, the latter investigated under both misspecified and correctly specified models. The methods are applied to data from a randomized clinical trial of three toothpaste formulations to prevent incident dental caries in a large population of Scottish schoolchildren. © The Author(s) 2014.

Effect of folic acid on appetite in children: ordinal logistic and fuzzy logistic regressions.

Science.gov (United States)

Namdari, Mahshid; Abadi, Alireza; Taheri, S Mahmoud; Rezaei, Mansour; Kalantari, Naser; Omidvar, Nasrin

2014-03-01

Reduced appetite and low food intake are often a concern in preschool children, since it can lead to malnutrition, a leading cause of impaired growth and mortality in childhood. It is occasionally considered that folic acid has a positive effect on appetite enhancement and consequently growth in children. The aim of this study was to assess the effect of folic acid on the appetite of preschool children 3 to 6 y old. The study sample included 127 children ages 3 to 6 who were randomly selected from 20 preschools in the city of Tehran in 2011. Since appetite was measured by linguistic terms, a fuzzy logistic regression was applied for modeling. The obtained results were compared with a statistical ordinal logistic model. After controlling for the potential confounders, in a statistical ordinal logistic model, serum folate showed a significantly positive effect on appetite. A small but positive effect of folate was detected by fuzzy logistic regression. Based on fuzzy regression, the risk for poor appetite in preschool children was related to the employment status of their mothers. In this study, a positive association was detected between the levels of serum folate and improved appetite. For further investigation, a randomized controlled, double-blind clinical trial could be helpful to address causality. Copyright © 2014 Elsevier Inc. All rights reserved.

Sample size adjustments for varying cluster sizes in cluster randomized trials with binary outcomes analyzed with second-order PQL mixed logistic regression.

Science.gov (United States)

Candel, Math J J M; Van Breukelen, Gerard J P

2010-06-30

Adjustments of sample size formulas are given for varying cluster sizes in cluster randomized trials with a binary outcome when testing the treatment effect with mixed effects logistic regression using second-order penalized quasi-likelihood estimation (PQL). Starting from first-order marginal quasi-likelihood (MQL) estimation of the treatment effect, the asymptotic relative efficiency of unequal versus equal cluster sizes is derived. A Monte Carlo simulation study shows this asymptotic relative efficiency to be rather accurate for realistic sample sizes, when employing second-order PQL. An approximate, simpler formula is presented to estimate the efficiency loss due to varying cluster sizes when planning a trial. In many cases sampling 14 per cent more clusters is sufficient to repair the efficiency loss due to varying cluster sizes. Since current closed-form formulas for sample size calculation are based on first-order MQL, planning a trial also requires a conversion factor to obtain the variance of the second-order PQL estimator. In a second Monte Carlo study, this conversion factor turned out to be 1.25 at most. (c) 2010 John Wiley & Sons, Ltd.

Managing Reverse Logistics or Reversing Logistics Management?

OpenAIRE

Brito, Marisa

2004-01-01

textabstractIn the past, supply chains were busy fine-tuning the logistics from raw material to the end customer. Today an increasing flow of products is going back in the chain. Thus, companies have to manage reverse logistics as well.This thesis contributes to a better understanding of reverse logistics. The thesis brings insights on reverse logistics decision-making and it lays down theoretical principles for reverse logistics as a research field.In particular it puts together a framework ...

An Evidenced-Based Scale of Disease Severity following Human Challenge with Enteroxigenic Escherichia coli.

Directory of Open Access Journals (Sweden)

Chad K Porter

Full Text Available Experimental human challenge models have played a major role in enhancing our understanding of infectious diseases. Primary outcomes have typically utilized overly simplistic outcomes that fail to entirely account for complex illness syndromes. We sought to characterize clinical outcomes associated with experimental infection with enterotoxigenic Escherichia coli (ETEC and to develop a disease score.Data were obtained from prior controlled human ETEC infection studies. Correlation and univariate regression across sign and symptom severity was performed. A multiple correspondence analysis was conducted. A 3-parameter disease score with construct validity was developed in an iterative fashion, compared to standard outcome definitions and applied to prior vaccine challenge trials.Data on 264 subjects receiving seven ETEC strains at doses from 1x105 to 1x1010 cfu were used to construct a standardized dataset. The strongest observed correlation was between vomiting and nausea (r = 0.65; however, stool output was poorly correlated with subjective activity-impacting outcomes. Multiple correspondence analyses showed covariability in multiple signs and symptoms, with severity being the strongest factor corresponding across outcomes. The developed disease score performed well compared to standard outcome definitions and differentiated disease in vaccinated and unvaccinated subjects.Frequency and volumetric definitions of diarrhea severity poorly characterize ETEC disease. These data support a disease severity score accounting for stool output and other clinical signs and symptoms. Such a score could serve as the basis for better field trial outcomes and gives an additional outcome measure to help select future vaccines that warrant expanded testing in pivotal pre-licensure trials.

Comprehensive Logistics

CERN Document Server

Gudehus, Timm

2012-01-01

Modern logistics comprises operative logistics, analytical logistics and management of logistic networks. Central task of operative logistics is the efficient supply of required goods at the right place within the right time. Tasks of analytical logistics are designing optimal networks and systems, developing strategies for planning, scheduling and operation, and organizing efficient order and performance processes. Logistic management plans, implements and operates logistic networks and schedules orders, stocks and resources. This reference-book offers a unique survey of modern logistics. It contains proven strategies, rules and tools for the solution of a multitude of logistic problems. The analytically derived algorithms and formulas can be used for the computer-based planning of logistic systems and for the dynamic scheduling of orders and resources in supply networks. They enable significant improvements of performance, quality and costs. Their application is demonstrated by several examples from industr...

Reflexões sobre mediação pedagógica em programas de formação a distância (e-TEC Brasil)

OpenAIRE

Queiroz, Magali Aparecida Mendes; IFTM- Instituto Federal de Educação Ciência e Tecnologia do Triângulo Mineiro

2012-01-01

Resumo: A educação a distância é hoje uma realidade, não só em cursos de nível superior, mas também em nível médio como é o caso do Programa Escola Técnica Aberta do Brasil (e-TEC Brasil), do Ministério da Educação. Este artigo faz uma análise sobre a mediação pedagógica nesta modalidade de ensino no tocante ao papel do professor frente a este novo paradigma e a sua abrangência social e educacional. As reflexões teóricas fundamentam-se em Lima (2007), Behrens (2000), Moran (2003), Lévy (2000)...

Education in logistics and training of non-logistic personnel

Directory of Open Access Journals (Sweden)

Marko D. Andrejić

2011-01-01

Full Text Available The significance of education in logistics and education and training of cadets who belong to non-logistic services (non-logistic personnel will be presented. The logistical aspects of education of non-logistic personnel are elaborated as well as the knowledge in the area of logistics which is necessary to be transferred through the educational process to non-logistic personnel for the successful accomplishment of their functional duties. A general approach and the methods of logistics education and improvement of non-logistic personnel are presented as well as the institutional prerequisites necessary for improving the quality of logistics education and training. The quality of the knowledge in this area and its implementation into the methods of thinking and decision making of non-logistic personnel affect the cooperation between the non-logistic and the logistic personnel, directly contributing to the quality of life and working conditions of units and institutions as well as to the quality and synergy in task accomplishments in the framework defined by the missions of the Army of Serbia. The necessary content and means of its transfer to cadets are discussed since they are supposed to be available at all levels and forms of education, depending on the previous cadet education levels. The theoretical bases and experiences shown are of general character and they have a universal application in the process of education. Introduction In our recent defense theory and operational practice, logistics education of non-logistic personnel is not sufficiently analyzed either in organizational or technological aspects, considering the concept and the logic of a systematic and a situational approach. The analysis of the experiences gained from operational practice shows a slight decrease in the quality of task accomplishment due to the lack of necessary logistic knowledge and habits as well as an increased communication gap between logistic and non-logistic

Relationship Between Green Logistics Tendency and Logistics Performance: A Comparative Case Study on Logistics Service Providers

OpenAIRE

Ayşenur DOĞRU; Cemile SOLAK FIŞKIN

2016-01-01

Increasing concerns related to environmental side effects of the logistics services and competition between the logistics service providers are two pressuring factors on logistics service providers. This study seeks to explore the relation between green logistics tendency and logistic performance from the perspective of logistics service providers. In order to reach this aim, two logistics service providers are investigated by comparative case study method. Findings showed the effects of g...

Logistics and logistics support in crisis management and citizen protection

OpenAIRE

HOLEJŠOVSKÝ, Jan

2010-01-01

ABSTRAKT LOGISTICS AND LOGISTICS SUPPORT IN CRISIS MANAGEMENT AND CITIZEN PROTECTION The graduation thesis on topic "Logistics and logistics support in crisis management and citizen protection" is divided into several chapters, which in summary are a material presenting information about logistics and logistics support in crisis management and citizen protection. This was one of the aims at this work. Chapters I., II., III., IV. describe logistics and logistics support, crisis management, cit...

Warehouse Logistics

OpenAIRE

Panibratetc, Anastasiia

2015-01-01

This research is a review of warehouse logistics on the example of Kannustalo Oy, located in Kannus, Western region of Finland. Kannustalo is an international company of designing, manufacturing and assembling block and turn-key houses. The research subject is logistics process in warehouse system of industrial company. In my work I discussed about theoretical aspect of logistics, logistic functions and processes. Later I considered warehouse as a part of logistics system and provided inf...

Research on the Logistics Supply Chain in Port Logistics Transportation

OpenAIRE

Wang Yan-liang

2013-01-01

The aim of this study is to improve and increase the logistics system effectiveness and to solve the problem of optimal movement of different flows. Logistics transport carrying the world on material resources transfer exchange important mission and economic development and our lives are closely linked, logistics chain logistics transport occupies an important position and in the e logistics chain in port logistics has play a decisive role. For many coastal countries port logistics is the eco...

Empirical Study of E-logistics System Based on Tibet Logistics Industry

OpenAIRE

Liu, Yu

2013-01-01

With the rapid growth of E-logistics in the global logistics industry, it is important to get insight into E-logistics system in Chinese logistics industry. Regarding the current situation of E-logistics of Chinese logistics industry, there are still many problems to be concerned and resolved. This paper will review the concepts and theoretical background of E-logistics System from previous researches. After acknowledging the essential issues on E-logistics System, a research model is designe...

Indices system design of distribution logistics, transport logistics and materials flow as parts of controlling in enterprise´s logistics

Directory of Open Access Journals (Sweden)

Andrea Rosová

2010-02-01

Full Text Available There is necessary to think about two aspects while applying controlling in logistics. The main aim of the logistics in relationto business economics is assessing support to the invested financial capital resources – it is the first aspect. The second one is basedon the target of controlling – continuous monitoring of company’s economy. In order to make a logistics controlling successful and withrequired results it is necessary to utilize any logistics controlling tools. One of the tools in logistics controlling is a set of indicators.Important part of controlling logistics system is monitoring and evaluation of logistics markers. Logistic markers representsynthetic view to logistic performance and logistic costs by the means of interaction rate so that it can evaluate logistic activities area,cost economy and final productivity of logistics activities in company.This contribution deals with markers system proposal of distribution logistics, transport logistics and materials flow control.System of markers is designed with regard to basic facilities and specifications, who has to copy character and disposition rememberedsubsystems enterprise’s logistics system.

Reverse Logistics

OpenAIRE

Kulikova, Olga

2016-01-01

This thesis was focused on the analysis of the concept of reverse logistics and actual reverse processes which are implemented in mining industry and finding solutions for the optimization of reverse logistics in this sphere. The objective of this paper was the assessment of the development of reverse logistics in mining industry on the example of potash production. The theoretical part was based on reverse logistics and mining waste related literature and provided foundations for further...

Logistics Reduction: RFID Enabled Autonomous Logistics Management (REALM)

Data.gov (United States)

National Aeronautics and Space Administration — The Advanced Exploration Systems (AES) Logistics Reduction (LR) project Radio-frequency identification (RFID) Enabled Autonomous Logistics Management (REALM) task...

Relationship Between Logistics Service's Perceived Value and Outsourcing of Logistics Activities

Directory of Open Access Journals (Sweden)

Klavdij Logožar

2006-07-01

Full Text Available Outsourcing has become increasingly popular in recentyears, and is often quoted as a means of coping with rapidchanges in technology and in the business environment. Thescope of third -party logistics may range from a relatively limitedcombination of activities (e. g. transportation and warehousingto a comprehensive set of logistics services. The authorsfirst define the reasons for outsourcing with the emphasis onbusiness logistics. They particularly point out the motivationsfor logistics outsourcing, the possibilities of logistics outsourcing,and they present the process of outsourcing partner selectionas well. Finally, they analyze the specific issues of logisticsservice's perceived value in outsourcing logistics activities onthe basis of the survey carried out in Slovenian companies. Thepurpose of the survey was to measure the customers' perceptionof different characteristics of logistics provider which can be decisivewhen manufacturing firms are trying to make a decisionwhether to outsource and which logistics provider to select. Thepaper creates a framework for the selection of the importantand perceived characteristics of logistics provider relevant tocustomer in the process of the logistics supplier selection.

Logistic chain modelling

NARCIS (Netherlands)

Slats, P.A.; Bhola, B.; Evers, J.J.M.; Dijkhuizen, G.

1995-01-01

Logistic chain modelling is very important in improving the overall performance of the total logistic chain. Logistic models provide support for a large range of applications, such as analysing bottlenecks, improving customer service, configuring new logistic chains and adapting existing chains to

Potential misinterpretation of treatment effects due to use of odds ratios and logistic regression in randomized controlled trials.

Directory of Open Access Journals (Sweden)

Mirjam J Knol

Full Text Available BACKGROUND: In randomized controlled trials (RCTs, the odds ratio (OR can substantially overestimate the risk ratio (RR if the incidence of the outcome is over 10%. This study determined the frequency of use of ORs, the frequency of overestimation of the OR as compared with its accompanying RR in published RCTs, and we assessed how often regression models that calculate RRs were used. METHODS: We included 288 RCTs published in 2008 in five major general medical journals (Annals of Internal Medicine, British Medical Journal, Journal of the American Medical Association, Lancet, New England Journal of Medicine. If an OR was reported, we calculated the corresponding RR, and we calculated the percentage of overestimation by using the formula . RESULTS: Of 193 RCTs with a dichotomous primary outcome, 24 (12.4% presented a crude and/or adjusted OR for the primary outcome. In five RCTs (2.6%, the OR differed more than 100% from its accompanying RR on the log scale. Forty-one of all included RCTs (n = 288; 14.2% presented ORs for other outcomes, or for subgroup analyses. Nineteen of these RCTs (6.6% had at least one OR that deviated more than 100% from its accompanying RR on the log scale. Of 53 RCTs that adjusted for baseline variables, 15 used logistic regression. Alternative methods to estimate RRs were only used in four RCTs. CONCLUSION: ORs and logistic regression are often used in RCTs and in many articles the OR did not approximate the RR. Although the authors did not explicitly misinterpret these ORs as RRs, misinterpretation by readers can seriously affect treatment decisions and policy making.

Managing Reverse Logistics or Reversing Logistics Management?

NARCIS (Netherlands)

M.P. de Brito (Marisa)

2004-01-01

textabstractIn the past, supply chains were busy fine-tuning the logistics from raw material to the end customer. Today an increasing flow of products is going back in the chain. Thus, companies have to manage reverse logistics as well.This thesis contributes to a better understanding of reverse

Complex logistics audit system

Directory of Open Access Journals (Sweden)

Zuzana Marková

2010-02-01

Full Text Available Complex logistics audit system is a tool for realization of logistical audit in the company. The current methods for logistics auditare based on “ad hok” analysis of logisticsl system. This paper describes system for complex logistics audit. It is a global diagnosticsof logistics processes and functions of enterprise. The goal of logistics audit is to provide comparative documentation for managementabout state of logistics in company and to show the potential of logistics changes in order to achieve more effective companyperformance.

A note on Verhulst's logistic equation and related logistic maps

International Nuclear Information System (INIS)

Gutierrez, M Ranferi; Reyes, M A; Rosu, H C

2010-01-01

We consider the Verhulst logistic equation and a couple of forms of the corresponding logistic maps. For the case of the logistic equation we show that using the general Riccati solution only changes the initial conditions of the equation. Next, we consider two forms of corresponding logistic maps reporting the following results. For the map x n+1 = rx n (1 - x n ) we propose a new way to write the solution for r = -2 which allows better precision of the iterative terms, while for the map x n+1 - x n = rx n (1 - x n+1 ) we show that it behaves identically to the logistic equation from the standpoint of the general Riccati solution, which is also provided herein for any value of the parameter r.

LOGISTICS OPTIMIZATION USING ONTOLOGIES

OpenAIRE

Hendi , Hayder; Ahmad , Adeel; Bouneffa , Mourad; Fonlupt , Cyril

2014-01-01

International audience; Logistics processes involve complex physical flows and integration of different elements. It is widely observed that the uncontrolled processes can decline the state of logistics. The optimization of logistic processes can support the desired growth and consistent continuity of logistics. In this paper, we present a software framework for logistic processes optimization. It primarily defines logistic ontologies and then optimize them. It intends to assist the design of...

Toward sustainable logistics

NARCIS (Netherlands)

Soysal, Mehmet; Bloemhof-Ruwaard, Jacqueline M.

2017-01-01

The fast evolution of sustainability leads to the development of a new fast-growing concept called sustainable logistics management. This research addresses recent business trends and challenges in logistics and their implications for sustainable logistics management. Additionally, we discuss policy

Toward sustainable logistics

NARCIS (Netherlands)

Soysal, Mehmet; Bloemhof-Ruwaard, Jacqueline M.

2018-01-01

The fast evolution of sustainability leads to the development of a new fast-growing concept called sustainable logistics management. This research addresses recent business trends and challenges in logistics and their implications for sustainable logistics management. Additionally, we discuss policy

The Relationship between Logistics Sophistication and Drivers of the Outsourcing of Logistics Activities

Directory of Open Access Journals (Sweden)

Peter Wanke

2008-10-01

Full Text Available A strong link has been established between operational excellence and the degree of sophistication of logistics organization, a function of factors such as performance monitoring, investment in Information Technology [IT] and the formalization of logistics organization, as proposed in the Bowersox, Daugherty, Dröge, Germain and Rogers (1992 Leading Edge model. At the same time, shippers have been increasingly outsourcing their logistics activities to third party providers. This paper, based on a survey with large Brazilian shippers, addresses a gap in the literature by investigating the relationship between dimensions of logistics organization sophistication and drivers of logistics outsourcing. To this end, the dimensions behind the logistics sophistication construct were first investigated. Results from factor analysis led to the identification of six dimensions of logistics sophistication. By means of multivariate logistical regression analyses it was possible to relate some of these dimensions, such as the formalization of the logistics organization, to certain drivers of the outsourcing of logistics activities of Brazilian shippers, such as cost savings. These results indicate the possibility of segmenting shippers according to characteristics of their logistics organization, which may be particularly useful to logistics service providers.

Management of Logistics Planning

OpenAIRE

Bjørnar Aas; Stein W. Wallace

2010-01-01

Logistics problems are gradually becoming more complex and a better understanding of logistics management as a subject is a key to deal with the new challenges. A core element of logistics management is logistics planning, which substitutes for low customer service levels, high waste, and the use of buffers and slacks in the execution of logistic activities. Furthermore, the availability of information and problem-solving capabilities are established as the core parts of logistics planning. B...

Logistics strategic decisions

NARCIS (Netherlands)

Steadie Seifi, M.; Farahani, R.Z.; Rezapour, S.; Kardar, L.

2011-01-01

Logistics has an important economic role because it swallows the biggest part of capital and supports the flow and movement of many economic transactions. Therefore, designing the best logistics strategies is vital. In this chapter, we take a look at different kinds of logistics decisions,

Logistical Worlds

Directory of Open Access Journals (Sweden)

Ned Rossiter

2014-03-01

Full Text Available As the managerial art and science of coordinating the movement of people, finance and things, logistical operations are central to contemporary capital. Despite its materiality in the form of communications and transport infrastructure, logistics remains an abstract machine for many. This is largely due to the compartmental structure of global supply chains and the invisibility of code. In registering the mediating force of logistics, the essay considers parametric politics as an architecture of intervention for both game design and software development. There are implications here not only for gameplay, but also the invention of method and governance of labour. How, for instance, might game design facilitate the production of a political knowledge of logistics? This becomes a matter to address for labour power vis-à-vis collective research on infrastructure, software and global supply chains.

The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.

Science.gov (United States)

Strigo, Tara S; Ephraim, Patti L; Pounds, Iris; Hill-Briggs, Felicia; Darrell, Linda; Ellis, Matthew; Sudan, Debra; Rabb, Hamid; Segev, Dorry; Wang, Nae-Yuh; Kaiser, Mary; Falkovic, Margaret; Lebov, Jill F; Boulware, L Ebony

2015-10-09

Live donor kidney transplantation (LDKT), an optimal therapy for many patients with end-stage kidney disease, is underutilized, particularly by African Americans. Potential recipient difficulties initiating and sustaining conversations about LDKT, identifying willing and medically eligible donors, and potential donors' logistical and financial hurdles have been cited as potential contributors to race disparities in LDKT. Few interventions specifically targeting these factors have been tested. We report the protocol of the Talking about Living Kidney Donation Support (TALKS) study, a study designed to evaluate the effectiveness of behavioral, educational and financial assistance interventions to improve access to LDKT among African Americans on the deceased donor kidney transplant recipient waiting list. We adapted a previously tested educational and social worker intervention shown to improve consideration and pursuit of LDKT among patients and their family members for its use among patients on the kidney transplant waiting list. We also developed a financial assistance intervention to help potential donors overcome logistical and financial challenges they might face during the pursuit of live kidney donation. We will evaluate the effectiveness of these interventions by conducting a randomized controlled trial in which patients on the deceased donor waiting list receive 1) usual care while on the transplant waiting list, 2) the educational and social worker intervention, or 3) the educational and social worker intervention plus the option of participating in the financial assistance program. The primary outcome of the randomized controlled trial will measure potential recipients' live kidney donor activation (a composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) at 1 year. The TALKS study will rigorously assess the effectiveness of promising interventions to reduce race disparities in LDKT. NCT02369354.

Regional logistics land allocation policies: stimulating spatial concentration of logistics firms

NARCIS (Netherlands)

Heuvel, van den F.P.; Langen, de P.W.; Donselaar, van K.H.; Fransoo, J.C.

2013-01-01

Although spatial concentration of logistics firms in logistics concentration areas can be beneficial for society at large, there is not much research on the relationship between land allocation policies and logistics concentration areas. This paper analyzes land allocation policies by means of a

Regional logistics land allocation policies : stimulating spatial concentration of logistics firms

NARCIS (Netherlands)

Heuvel, van den F.P.; Langen, de P.W.; Donselaar, van K.H.; Fransoo, J.C.

2013-01-01

Although spatial concentration of logistics firms in logistics concentration areas can be beneficial for society at large, there is not much research on the relationship between land allocation policies and logistics concentration areas. This paper analyzes land allocation policies by means of a

Management and logistics

OpenAIRE

Jereb, Borut; Drašković, Mimo; Gorenak, Irena; Bauk, Sanja; Fošner, Maja; Rosi, Bojan; Pupavac, Drago; Topolšek, Darja; Dorokhov, Oleksandr; Kramar, Uroš; Ivanović, Željko; Sternad, Marjan; Knez, Matjaž; Mlaker Kač, Sonja; Malyaretz, Ludmila

2018-01-01

The scientific monograph titled Logistics and Management – selected topics is the result of a bilateral project, lasting from 2013 to 2015 and titled “Preparation of a joint scientific monograph in the field of logistics and management issued at the Faculty of Logistics in Celje and the Maritime Faculty of Kotor”. The project was managed by Professor Maja Fošner, PhD, from the Faculty of Logistics at the University of Maribor, and Professor Veselin Draskovic, PdD, from the Maritime Faculty of...

Improving Healthcare Logistics Processes

DEFF Research Database (Denmark)

Feibert, Diana Cordes

logistics processes in hospitals and aims to provide theoretically and empirically based evidence for improving these processes to both expand the knowledge base of healthcare logistics and provide a decision tool for hospital logistics managers to improve their processes. Case studies were conducted...... processes. Furthermore, a method for benchmarking healthcare logistics processes was developed. Finally, a theoretically and empirically founded framework was developed to support managers in making an informed decision on how to improve healthcare logistics processes. This study contributes to the limited...... literature concerned with the improvement of logistics processes in hospitals. Furthermore, the developed framework provides guidance for logistics managers in hospitals on how to improve their processes given the circumstances in which they operate....

Smart logistics

NARCIS (Netherlands)

Woensel, van T.

2012-01-01

This lecture focuses on Smart Logistics referring to these intelligent managerial decisions related to the design, operations and control of the transportation chain processes in an efficient and cost-effective way. The starting point for Smart Logistics is the key observation that the real-life

Computational Logistics

DEFF Research Database (Denmark)

Pacino, Dario; Voss, Stefan; Jensen, Rune Møller

2013-01-01

This book constitutes the refereed proceedings of the 4th International Conference on Computational Logistics, ICCL 2013, held in Copenhagen, Denmark, in September 2013. The 19 papers presented in this volume were carefully reviewed and selected for inclusion in the book. They are organized in to...... in topical sections named: maritime shipping, road transport, vehicle routing problems, aviation applications, and logistics and supply chain management.......This book constitutes the refereed proceedings of the 4th International Conference on Computational Logistics, ICCL 2013, held in Copenhagen, Denmark, in September 2013. The 19 papers presented in this volume were carefully reviewed and selected for inclusion in the book. They are organized...

Computational Logistics

DEFF Research Database (Denmark)

This book constitutes the refereed proceedings of the 4th International Conference on Computational Logistics, ICCL 2013, held in Copenhagen, Denmark, in September 2013. The 19 papers presented in this volume were carefully reviewed and selected for inclusion in the book. They are organized in to...... in topical sections named: maritime shipping, road transport, vehicle routing problems, aviation applications, and logistics and supply chain management.......This book constitutes the refereed proceedings of the 4th International Conference on Computational Logistics, ICCL 2013, held in Copenhagen, Denmark, in September 2013. The 19 papers presented in this volume were carefully reviewed and selected for inclusion in the book. They are organized...

Logistics costs of the enterprise

Directory of Open Access Journals (Sweden)

Andrea Rosová

2007-06-01

Full Text Available The article describe a problem of specification and systematization of enterprise’s logistics costs. With in a growing division of labour, also logistics costs increase their part in enterprises total costs.Almost all decisions about products and production in general, influence logistics processes even logistics costs and performances.In present is not clear enough, which of the cost-particles are relevant fot logistics costs, because some of logistics cost-particles accounts within overhead are charged together with costs of other sorts.Substantive step in the process of the monitoring and evidence of logistics costs is definition of this, that costs of enterprise´s processes will be inclusive in logistics costs and determining points of contact with the others departments (acquisition, production, sale etc.. After the specification of meditation processes, there is a need to choose applicable parameters for the expression of logistics performances. Besides logistics costs is needed to know logistics performances equivalent herewith at a cost of, therefore from the control side have for enterprise bigger value indices expressive correlation costs and performances(e.g. share of logistics unit costs performance.At the proposal and evidence of logistics costs and performances is needed consistently entertain an individual conditions of enterprise. Because the area of processes included strongly affects the size of account logistics costs and its share part in total costs of enterprise. Logistics costs are flow line between economy and logistics of the enterprise.

Harvesting forest biomass for energy in Minnesota: An assessment of guidelines, costs and logistics

Science.gov (United States)

Saleh, Dalia El Sayed Abbas Mohamed

The emerging market for renewable energy in Minnesota has generated a growing interest in utilizing more forest biomass for energy. However, this growing interest is paralleled with limited knowledge of the environmental impacts and cost effectiveness of utilizing this resource. To address environmental and economic viability concerns, this dissertation has addressed three areas related to biomass harvest: First, existing biomass harvesting guidelines and sustainability considerations are examined. Second, the potential contribution of biomass energy production to reduce the costs of hazardous fuel reduction treatments in these trials is assessed. Third, the logistics of biomass production trials are analyzed. Findings show that: (1) Existing forest related guidelines are not sufficient to allow large-scale production of biomass energy from forest residue sustainably. Biomass energy guidelines need to be based on scientific assessments of how repeated and large scale biomass production is going to affect soil, water and habitat values, in an integrated and individual manner over time. Furthermore, such guidelines would need to recommend production logistics (planning, implementation, and coordination of operations) necessary for a potential supply with the least site and environmental impacts. (2) The costs of biomass production trials were assessed and compared with conventional treatment costs. In these trials, conventional mechanical treatment costs were lower than biomass energy production costs less income from biomass sale. However, a sensitivity analysis indicated that costs reductions are possible under certain site, prescriptions and distance conditions. (3) Semi-structured interviews with forest machine operators indicate that existing fuel reduction prescriptions need to be more realistic in making recommendations that can overcome operational barriers (technical and physical) and planning and coordination concerns (guidelines and communications

Logistics in Estonian business companies

Directory of Open Access Journals (Sweden)

A. Kiisler

2008-12-01

Full Text Available The article describes logistics survey in Estonia carried out in 2007 as a part of the LogOnBaltic project. The level of logistics in Estonian manufacturing, trading and logistics companies is explored through logistics costs, performance indicators, outsourcing, ICT use and logistics self-estimation of the companies responded. Responses from 186 Estonian companies were gathered through a web-based survey (38% of manufacturing, 38% of trading and 24% of logistics sector. Logistics costs as the percentage of turnover make in average 13.8% in manufacturing and 13.3% in trading. Transportation and inventory carrying cost form around 70% of overall logistics costs. Considering the logistics indicators surveyed, Estonian companies show up with relatively low perfect order fulfillment rates, short customer order fulfillment cycles and effective management of cash flows. The most widely outsourced logistics function is international transportation followed by domestic transportation, freight forwarding and reverse logistics. By 2010, the outsourcing of IT systems in logistics followed by inventory management, warehousing and product customization is expected to increase more substantially. The awareness of logistics importance is still low among Estonian companies. Only 27–44% of those agree that logistics has a considerable impact on profitability, competitive advantage, top management or customer service level.

KSC ISS Logistics Support

Science.gov (United States)

Tellado, Joseph

2014-01-01

The presentation contains a status of KSC ISS Logistics Operations. It basically presents current top level ISS Logistics tasks being conducted at KSC, current International Partner activities, hardware processing flow focussing on late Stow operations, list of KSC Logistics POC's, and a backup list of Logistics launch site services. This presentation is being given at the annual International Space Station (ISS) Multi-lateral Logistics Maintenance Control Panel meeting to be held in Turin, Italy during the week of May 13-16. The presentatiuon content doesn't contain any potential lessons learned.

WAREOOUSE LOGISTICS MANAGEMENT

OpenAIRE

Drago Pupavac

2012-01-01

Warehouse Logistics Management involves the management of storage facilities and equipment, stock, employees and technology with the aim of efficient storage, accommodation, and distribution of goods and more importantly profitably. In conditions of economic crisis and lower inventory turns, logistics managers put emphasis on those measures as a function of storage logistics cost reductions that require minimal investment. Accordingly, the fundamental objective of this scientific paper is to ...

LOGISTICS - EVOLUTION THROUGH INNOVATION

Directory of Open Access Journals (Sweden)

Petrache Alexandru Constantin

2015-07-01

Full Text Available The current economic conditions, the rapidity with which the exchange of information, resources and products in the market takes place makes the logistics seem appreciably less significant. However, the importance of logistics has been presented in the military field, through strategies that have led to wining of the great wars that mankind has seen, through the supply of troops with food or moving military equipment. The literature in the field of logistics has numerous works on this topic. But while most focuses on efficient ways of carrying out the component activities of logistics or the strategies of organizations with regard to logistics or its functions, research on dynamics of logistics is underdeveloped. To be able to propose new methods or strategies of logistic activities is necessary to understand the development of this concept, determinant factors and economic and social conditions that gave rise to such developments. Thus, after a presentation of the main landmarks of the historical development of logistics we highlight the importance of the innovation within an organization's value chain innovation, in particular, and how to conduct the business in general. Using generations of innovation identified in the literature, we determine the generation of logistics development, taking into account innovation and how to conduct business. In addition for a better highlight of the own vision over the logistics generations identified, we will present the graphical concept for each generation in part. Last but not least, for each generation identified we try to allocate the chronological landmarks featured in order to reinforce the importance played by innovation in the development of the logistics industry and to give future directions of research within this topic. The study took into account the information presented in articles, books and websites of the relevant specialty in logistics and innovation to be able to build and expose a

A grey DEMATEL approach to develop third-party logistics provider selection criteria

DEFF Research Database (Denmark)

Govindan, Kannan; Khodaverdi, Roohollah; Vafadarnikjoo, Amin

2016-01-01

- The paper's results help managers of automotive industries, particularly in developing countries, to outsource logistics activities to 3PL providers effectively and to create a significant competitive advantage. Originality/value - The main contributions of this paper are twofold. First, this paper proposes...... an integrated grey DEMATEL method to consider interdependent relationships among the 3PL provider selection criteria. Second, this study is one of the first studies to consider 3PL provider selection in a developing country like Iran....... identifies important criteria for 3PL provider selection and evaluation, and the purpose of this paper is to select 3PL providers from the viewpoint of firms which were already outsourcing their logistics services. Design/methodology/approach - This study utilized the grey decision-making trial...

Logistics Innovation Process Revisited

DEFF Research Database (Denmark)

Gammelgaard, Britta; Su, Shong-Iee Ivan; Yang, Su-Lan

2011-01-01

Purpose – The purpose of this paper is to learn more about logistics innovation processes and their implications for the focal organization as well as the supply chain, especially suppliers. Design/methodology/approach – The empirical basis of the study is a longitudinal action research project...... that was triggered by the practical needs of new ways of handling material flows of a hospital. This approach made it possible to revisit theory on logistics innovation process. Findings – Apart from the tangible benefits reported to the case hospital, five findings can be extracted from this study: the logistics...... innovation process model may include not just customers but also suppliers; logistics innovation in buyer-supplier relations may serve as an alternative to outsourcing; logistics innovation processes are dynamic and may improve supplier partnerships; logistics innovations in the supply chain are as dependent...

Total Logistic Plant Solutions

Directory of Open Access Journals (Sweden)

Dusan Dorcak

2016-02-01

Full Text Available The Total Logistics Plant Solutions, plant logistics system - TLPS, based on the philosophy of advanced control processes enables complex coordination of business processes and flows and the management and scheduling of production in the appropriate production plans and planning periods. Main attributes of TLPS is to create a comprehensive, multi-level, enterprise logistics information system, with a certain degree of intelligence, which accepts the latest science and research results in the field of production technology and logistics. Logistic model of company understands as a system of mutually transforming flows of materials, energy, information, finance, which is realized by chain activities and operations

A note on Verhulst's logistic equation and related logistic maps

Energy Technology Data Exchange (ETDEWEB)

Gutierrez, M Ranferi; Reyes, M A [Depto de Fisica, Universidad de Guanajuato, Apdo. Postal E143, 37150 Leon, Gto. (Mexico); Rosu, H C, E-mail: hcr@ipicyt.edu.m [IPICyT, Instituto Potosino de Investigacion Cientifica y Tecnologica, Apdo Postal 3-74 Tangamanga, 78231 San Luis PotosI (Mexico)

2010-05-21

We consider the Verhulst logistic equation and a couple of forms of the corresponding logistic maps. For the case of the logistic equation we show that using the general Riccati solution only changes the initial conditions of the equation. Next, we consider two forms of corresponding logistic maps reporting the following results. For the map x{sub n+1} = rx{sub n}(1 - x{sub n}) we propose a new way to write the solution for r = -2 which allows better precision of the iterative terms, while for the map x{sub n+1} - x{sub n} = rx{sub n}(1 - x{sub n+1}) we show that it behaves identically to the logistic equation from the standpoint of the general Riccati solution, which is also provided herein for any value of the parameter r.

Space Station fluid management logistics

Science.gov (United States)

Dominick, Sam M.

1990-01-01

Viewgraphs and discussion on space station fluid management logistics are presented. Topics covered include: fluid management logistics - issues for Space Station Freedom evolution; current fluid logistics approach; evolution of Space Station Freedom fluid resupply; launch vehicle evolution; ELV logistics system approach; logistics carrier configuration; expendable fluid/propellant carrier description; fluid carrier design concept; logistics carrier orbital operations; carrier operations at space station; summary/status of orbital fluid transfer techniques; Soviet progress tanker system; and Soviet propellant resupply system observations.

Accounting for center in the Early External Cephalic Version trials: an empirical comparison of statistical methods to adjust for center in a multicenter trial with binary outcomes.

Science.gov (United States)

Reitsma, Angela; Chu, Rong; Thorpe, Julia; McDonald, Sarah; Thabane, Lehana; Hutton, Eileen

2014-09-26

Clustering of outcomes at centers involved in multicenter trials is a type of center effect. The Consolidated Standards of Reporting Trials Statement recommends that multicenter randomized controlled trials (RCTs) should account for center effects in their analysis, however most do not. The Early External Cephalic Version (EECV) trials published in 2003 and 2011 stratified by center at randomization, but did not account for center in the analyses, and due to the nature of the intervention and number of centers, may have been prone to center effects. Using data from the EECV trials, we undertook an empirical study to compare various statistical approaches to account for center effect while estimating the impact of external cephalic version timing (early or delayed) on the outcomes of cesarean section, preterm birth, and non-cephalic presentation at the time of birth. The data from the EECV pilot trial and the EECV2 trial were merged into one dataset. Fisher's exact method was used to test the overall effect of external cephalic version timing unadjusted for center effects. Seven statistical models that accounted for center effects were applied to the data. The models included: i) the Mantel-Haenszel test, ii) logistic regression with fixed center effect and fixed treatment effect, iii) center-size weighted and iv) un-weighted logistic regression with fixed center effect and fixed treatment-by-center interaction, iv) logistic regression with random center effect and fixed treatment effect, v) logistic regression with random center effect and random treatment-by-center interaction, and vi) generalized estimating equations. For each of the three outcomes of interest approaches to account for center effect did not alter the overall findings of the trial. The results were similar for the majority of the methods used to adjust for center, illustrating the robustness of the findings. Despite literature that suggests center effect can change the estimate of effect in

Evaluating barriers for reverse logistics implementation under a multiple stakeholders' perspective analysis using grey decision making approach

DEFF Research Database (Denmark)

Bouzon, Marina; Govindan, Kannan; Rodriguez, Carlos Manuel Taboada

2018-01-01

In the past few decades, an interest in reverse logistics has attracted the attention of industries and also has become a subject of interest for researchers. However, while reverse logistics is becoming a mandatory element of the supply chain in developed countries particularly due to legislation...... issues, the subject is still in a state of infancy in emerging economies such as Brazil. In these connections, impediments to reverse logistics implementation must be considered and analyzed, as well as the many different perspectives from the key stakeholders for their development. The objective...... of this research is to evaluate the interrelationship among reverse logistics barriers from the perspectives of the most important stakeholders in the Brazilian context. For this purpose, a Multi-Criteria Decision Making tool named grey-based Decision Making Trial and Evaluation Laboratory (grey-DEMATEL) was used...

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

Science.gov (United States)

Sarker, Shafiqul Alam; Sultana, Shamima; Reuteler, Gloria; Moine, Deborah; Descombes, Patrick; Charton, Florence; Bourdin, Gilles; McCallin, Shawna; Ngom-Bru, Catherine; Neville, Tara; Akter, Mahmuda; Huq, Sayeeda; Qadri, Firdausi; Talukdar, Kaisar; Kassam, Mohamed; Delley, Michèle; Loiseau, Chloe; Deng, Ying; El Aidy, Sahar; Berger, Bernard; Brüssow, Harald

2016-01-01

Background Antibiotic resistance is rising in important bacterial pathogens. Phage therapy (PT), the use of bacterial viruses infecting the pathogen in a species-specific way, is a potential alternative. Method T4-like coliphages or a commercial Russian coliphage product or placebo was orally given over 4 days to Bangladeshi children hospitalized with acute bacterial diarrhea. Safety of oral phage was assessed clinically and by functional tests; coliphage and Escherichia coli titers and enteropathogens were determined in stool and quantitative diarrhea parameters (stool output, stool frequency) were measured. Stool microbiota was studied by 16S rRNA gene sequencing; the genomes of four fecal Streptococcus isolates were sequenced. Findings No adverse events attributable to oral phage application were observed (primary safety outcome). Fecal coliphage was increased in treated over control children, but the titers did not show substantial intestinal phage replication (secondary microbiology outcome). 60% of the children suffered from a microbiologically proven E. coli diarrhea; the most frequent diagnosis was ETEC infections. Bacterial co-pathogens were also detected. Half of the patients contained phage-susceptible E. coli colonies in the stool. E. coli represented less than 5% of fecal bacteria. Stool ETEC titers showed only a short-lived peak and were otherwise close to the replication threshold determined for T4 phage in vitro. An interim analysis after the enrollment of 120 patients showed no amelioration in quantitative diarrhea parameter by PT over standard care (tertiary clinical outcome). Stool microbiota was characterized by an overgrowth with Streptococcus belonging to the Streptococcus gallolyticus and Streptococcus salivarius species groups, their abundance correlated with quantitative diarrhea outcome, but genome sequencing did not identify virulence genes. Interpretation Oral coliphages showed a safe gut transit in children, but failed to achieve

Applied logistic regression

CERN Document Server

Hosmer, David W; Sturdivant, Rodney X

2013-01-01

 A new edition of the definitive guide to logistic regression modeling for health science and other applications This thoroughly expanded Third Edition provides an easily accessible introduction to the logistic regression (LR) model and highlights the power of this model by examining the relationship between a dichotomous outcome and a set of covariables. Applied Logistic Regression, Third Edition emphasizes applications in the health sciences and handpicks topics that best suit the use of modern statistical software. The book provides readers with state-of-

Logistics planning and logistics planning factors for humanitarian operations

OpenAIRE

Sullivan, Donna Marie.

1995-01-01

Due to the increasing demand on the military to conduct humanitarian operations, the need for logistics planning factors that are applicable to these operations has arisen. This thesis develops a model for humanitarian operations and employs the model to develop logistics planning factors for material consumption and a computer-assisted planning aid relating to the support of the victim population. U.S. Navy (U.S.N.) author.

In-plant logistics optimalization

OpenAIRE

Maroušek, Jan

2008-01-01

In a theoretical part of this work there is introduced a general view on logistics and its development, than a view on creating value for customer, basics of lean production, lean thinking and following methods as Six Sigma and Value Stream Mapping. At the end of the theoretical part there is mentioned outsourcing of logistics services and view on relationship between logistics provider and a client. In a practical part there is introduced a project of in-plant logistics optimalization in a f...

FEEDBACK AND LOGISTICS CONTROLLING

Directory of Open Access Journals (Sweden)

Mehesne Berek Szilvia

2015-07-01

Full Text Available The following things led to that the feedback, the supervision and improvement of the processes have become more pronounced: continuous rise in the importance of logistics; increase in complexity of its content; its activity becoming more complex. These activities are necessary for the optimum information supply. The intensification of market competition requires the corporations to possess exact and up-to-date information about their activities. Complexity of the logistics system presumes a parallel application of an effective feedback, supervision and management system simultaneously with the given logistics system. The indispensability of logistics is also proved by the fact that it can be found sporadically (in the form of logistics departments or in a complex way in case of each organization. The logistical approach means a huge support in the management since it contains the complexity, the handling as a unit in order to ensure a harmony of the different corporate departments and part activities. In addition to the professional application of a logistics system, there is an opportunity to coordinate the relations inside an organization as well as between the organizations and to handle them as a unit. The sine qua non of the success of logistical processes is a harmony of the devices applied. The controlling system is a device for feeding back the processes of a corporate system. By means of the checkpoints intercalated into the processes, the logistics controlling provides information for the leadership which contributes even more to the complex approach of logistics system. By dint of the logistics controlling, the monitoring and coordination of every logistical part activity become possible with the help of information supply ensured by the logistics controlling. The logistics controlling reviews, assesses and coordinates; these activities have an effect on the cost and income management. Its reason is to be searched in the built

Reverse logistics - a framework

NARCIS (Netherlands)

M.P. de Brito (Marisa); R. Dekker (Rommert)

2002-01-01

textabstractIn this paper we define and compare Reverse Logistics definitions. We start by giving an understanding framework of Reverse Logistics: the why-what-how. By this means, we put in context the driving forces for Reverse Logistics, a typology of return reasons, a classification of

Logistics centres development in Latvia

Directory of Open Access Journals (Sweden)

I. Kabashkin

2007-12-01

Full Text Available In the situation where a large increase in trade and freight transport volumes in the Baltic Sea region (BSR is expected and in which the BSR is facing a major economic restructuring, eff orts to achieve more integrated and sustainable transport and communication links within the BSR are needed. One of these eff orts is the development of logistics centres (LCs and their networking, which will continue to have an impact on improving communication links, spatial planning practices and approaches, logistics chain development and the promotion of sustainable transport modes. These factors will refl ect on logistics processes both in major gateway cities and in remote BSR areas. The importance of logistics systems as a whole is not seen clearly enough. Logistics actors see that logistics operations are not appreciated as much as other fi elds of activity. In addition, logistics centres and the importance of logistics activities to the business life of areas and the employment rate should be brought up better. In the paper main goal and tasks of national approach to LCs development are discussed. Strategic focus of new activities in this area is on the integration of various networks within and between logistics centres in order to improve and develop the quality of logistics networks as well as to spatially widen the networking activities. The key objectives are to integrate the links between logistics centres, ports and other logistics operators in a functional and sustainable way, to promote spatial integration by creating sustainable and integrated approaches to spatial planning of logistics centres and transport infrastructure, to improve ICT-based networking and communication practices of the fi elds of transport and logistics and to increase the competence of logistics centres and associated actors by organising educational and training events. The current activities include, for example, the creation of measures for transport networking and

SIMULATION OF LOGISTICS PROCESSES

Directory of Open Access Journals (Sweden)

Yu. Taranenko

2016-08-01

Full Text Available The article deals with the theoretical basis of the simulation. The study shows the simulation of logistic processes in industrial countries is an integral part of many economic projects aimed at the creation or improvement of logistics systems. The paper was used model Beer Game for management of logistics processes in the enterprise. The simulation model implements in AnyLogic package. AnyLogic product allows us to consider the logistics processes as an integrated system, which allows reaching better solutions. Logistics process management involves pooling the sales market, production and distribution to ensure the temporal level of customer service at the lowest cost overall. This made it possible to conduct experiments and to determine the optimal size of the warehouse at the lowest cost.

Green Maritime Logistics

DEFF Research Database (Denmark)

Psaraftis, Harilaos N.

2016-01-01

By green maritime logistics we mean achieving an acceptable environmental performance of the maritime transport logistical supply chain while at the same time respecting traditional economic criteria. In this paper the environmental focus is on maritime emissions. Achieving such goal may involve ...

Green Logistics Management

Science.gov (United States)

Chang, Yoon S.; Oh, Chang H.

Nowadays, environmental management becomes a critical business consideration for companies to survive from many regulations and tough business requirements. Most of world-leading companies are now aware that environment friendly technology and management are critical to the sustainable growth of the company. The environment market has seen continuous growth marking 532B in 2000, and 590B in 2004. This growth rate is expected to grow to 700B in 2010. It is not hard to see the environment-friendly efforts in almost all aspects of business operations. Such trends can be easily found in logistics area. Green logistics aims to make environmental friendly decisions throughout a product lifecycle. Therefore for the success of green logistics, it is critical to have real time tracking capability on the product throughout the product lifecycle and smart solution service architecture. In this chapter, we introduce an RFID based green logistics solution and service.

The logic of logistics: theory, algorithms and applications for logistics management

Directory of Open Access Journals (Sweden)

Claudio Barbieri da Cunha

2010-04-01

Full Text Available

Nesse texto o autor apresenta uma resenha acerca do livro "The logic of logistics: theory, algorithms and applications for logistics management", de autoria de Julien Bramel e David Simchi-Levi, publicado pela Springer-Verlag, em 1997.

Security in Logistics

Science.gov (United States)

Cempírek, Václav; Nachtigall, Petr; Široký, Jaromír

2016-12-01

This paper deals with security of logistic chains according to incorrect declaration of transported goods, fraudulent transport and forwarding companies and possible threats caused by political influences. The main goal of this paper is to highlight possible logistic costs increase due to these fraudulent threats. An analysis of technological processes will beis provided, and an increase of these transport times considering the possible threatswhich will beis evaluated economic costs-wise. In the conclusion, possible threat of companies'` efficiency in logistics due to the costs`, means of transport and increase in human resources` increase will beare pointed out.

Rice evapotranspiration at the field and canopy scales under water-saving irrigation

Science.gov (United States)

Liu, Xiaoyin; Xu, Junzeng; Yang, Shihong; Zhang, Jiangang

2018-04-01

Evapotranspiration (ET) is an important process of land surface water and thermal cycling, with large temporal and spatial variability. To reveal the effect of water-saving irrigation (WSI) on rice ET at different spatial scales and understand the cross spatial scale difference, rice ET under WSI condition at canopy (ETCML) and field scale (ETEC) were measured simultaneously by mini-lysimeter and eddy covariance (EC) in the rice season of 2014. To overcome the shortage of energy balance deficit by EC system, and evaluate the influence of energy balance closure degree on ETEC, ETEC was corrected as {ET}_{EC}^{*} by energy balance closure correction according to the evaporative fraction. Seasonal average daily ETEC, {ET}_{EC}^{*} and ETCML of rice under WSI practice were estimated as 3.12, 4.03 and 4.35 mm day-1, smaller than the values reported in flooded paddy fields. Daily ETEC, {ET}_{EC}^{*} and ETCML varied in a similar trends and reached the maximum in late tillering, then decreased along with the crop growth in late season. The value of ETEC was much lower than ETCML, and was frequently 1-2 h lagged behind ETCML. It indicated that the energy balance deficit resulted in underestimation of crop ET by EC system. The corrected value of {ET}_{EC}^{*} matched ETCML much better than ETEC, with a smaller RMSE (0.086 mm h-1) and higher R 2 (0.843) and IOA (0.961). The time lapse between {ET}_{EC}^{*} and ETCML was mostly shortened to less than 0.5 h. The multiple stepwise regression analysis indicated that net radiation ( R n) is the dominant factor for rice ET, and soil moisture ( θ) is another significant factor ( p rice fields. The difference between ETCML and {ET}_{EC}^{*} ({ET}_{CML} - {ET}_{EC}^{*}) were significantly ( p rice ET in WSI fields, and for its cross scale conversion.

A robust optimization model for green regional logistics network design with uncertainty in future logistics demand

Directory of Open Access Journals (Sweden)

Dezhi Zhang

2015-12-01

Full Text Available This article proposes a new model to address the design problem of a sustainable regional logistics network with uncertainty in future logistics demand. In the proposed model, the future logistics demand is assumed to be a random variable with a given probability distribution. A set of chance constraints with regard to logistics service capacity and environmental impacts is incorporated to consider the sustainability of logistics network design. The proposed model is formulated as a two-stage robust optimization problem. The first-stage problem before the realization of future logistics demand aims to minimize a risk-averse objective by determining the optimal location and size of logistics parks with CO2 emission taxes consideration. The second stage after the uncertain logistics demand has been determined is a scenario-based stochastic logistics service route choices equilibrium problem. A heuristic solution algorithm, which is a combination of penalty function method, genetic algorithm, and Gauss–Seidel decomposition approach, is developed to solve the proposed model. An illustrative example is given to show the application of the proposed model and solution algorithm. The findings show that total social welfare of the logistics system depends very much on the level of uncertainty in future logistics demand, capital budget for logistics parks, and confidence levels of the chance constraints.

A New Advanced Logistics Supply Chain for Food Management Based on Green Logistics Theory

OpenAIRE

Lanqing Liu

2013-01-01

The study aims to investigate the advanced logistics supply chain for food management using green logistics. To protect the food logistics environment and prevent the environmental pollution, it is crucial to establish powerful modern supply chains to support the food management in transportation. The construction speed of the food companies is very fast; however, the food supply lags behind the food companies. As a result, the environmental pollution caused in the food logistics becomes seve...

International Logistics Science Conference

CERN Document Server

Hompel, Michael; Meier, J

2014-01-01

The importance of logistics in all its variations is still increasing. New technologies emerge, new planning methods and algorithms are developed, only to face a market with a growing complexity and the need of weighting monetary costs against ecological impact. Mastering these challenges requires a scientific viewpoint on logistics, but always with applications in mind. This volume presents up-to-date logistics research in all its diversity and interconnectedness. It grew out of the “International Logistics Science Conference” (ILSC) held in Dortmund in September 2013, bringing together leading scientists and young academics from nine different countries. The conference was jointly organized by the “Efficiency Cluster Logistics” and the “Fraunhofer Institute for Material Flow and Logistics”. The Program Committee used a double blind review process to choose the 12 strongest contributions, which were then grouped in four areas: - Sustainability logistics, including electric mobility, smart inform...

Development of logistics information systems

Directory of Open Access Journals (Sweden)

Milan Ž. Dronjak

2012-10-01

Full Text Available An adequate logistics information system provides real time automated data processing, distribution and of information according to Terrain Commander's requirements, which leads to timely fulfillment of logistic demands of units. SAP ERP The SAP ERP application is the integrated (ERP software capable of working with complex organisational structures, personnel, equipment, and finance. It enables planning and combining forces for every type of operations. The system also enables the determination of the readiness status of modelled forces. ISL The Information System for Logistics (ISL is a comprehensive information system of the Ministry of Defence (MoD and the Army of the Czech Republic that covers many areas: acquisition, supply, ammunition and equipment maintenance, logistics, etc. The ISL provides support for military logistics in all important areas of consumer and acquisition logistics, satisfaying all kinds of Defence Forces needs in the country and abroad. LOGFAS The information system LOGFAS comprises Logistics Database (LOGBASE, Movement and Transportation software (M&T, Allied Command Europe Resource Optimisation Software System (ACROSS and Logistic Reporting System (LOGREP. The Logistics Database LOGBASE represents a logistics information source and also a database related to assets, forces, geography, infrastructure, targets, supplies, movements and medical data. The main software tools which rely on the LOGBASE are M&T, ACROSS and LOGREP. GCSS-Army The original impetus to create the SALE came in the mid-90s when the United States Department of Defense (DoD started a logistics modernisation programme. One of tasks was to build The Single Army Logistics Enterprise (SALE for the purpose of covering the whole organisational structure of the DoD. There are three components of the SALE: GCSS-Army, PLM+ and LMP. Each of them uses the commercial Enterprise Resource Planning SAP Software with a Web access. The main component, GCSS

The logic of logistics theory, algorithms, and applications for logistics management

CERN Document Server

Simchi-Levi, David; Bramel, Julien

2014-01-01

Fierce competition in today's global market provides a powerful motivation for developing ever more sophisticated logistics systems. This book, written for the logistics manager and researcher, presents a survey of the modern theory and application of logistics. The goal of the book is to present the state of the art in the science of logistics management. This third edition includes new chapters on the subjects of game theory, the power of process flexibility, supply chain competition and collaboration. Among the other materials new to the edition are sections on discrete convex analysis and its applications to stochastic inventory models, as well as extended discussions of integrated inventory and pricing models. The material presents a timely and authoritative survey of the field that will make an invaluable companion to the work of many researchers and practitioners.   Review of earlier edition:   "The present book focuses on the application of operational research and mathematical modelling technique...

The Emergence of City Logistics

DEFF Research Database (Denmark)

Gammelgaard, Britta

2015-01-01

is therefore to increase understanding of how city logistics emerge, and secondarily, to investigate whether such processes can be managed at all. Design/methodology/approach: – A paradigm shift in urban planning creates new ways of involving stakeholders in new sustainability measures such as city logistics...... dialectic forces were at play. City logistics schemes are still in an innovation phase. The biggest challenge in managing a process toward city logistics is to convince the many public and private stakeholders of their mutual interest and goals. Research limitations/implications: – Urban goods transport...... city logistics projects may fail. Thereby, cities become more environmentally and socially sustainable. Originality/value: – Insights into a city logistics project from a change management perspective has not previously been reported in literature....

The Logistics Knowledge Portal: Gateway to More Individualized Learning in Logistics.

Science.gov (United States)

Neumann, Gaby; Krzyzaniak, Stanislaw; Lassen, Carl Christian

This paper describes a research and development project initiated by a network of European logistics educators to promote all types, forms, and levels of logistics education by benefiting from the educational potential of multimedia/hypermedia as well as information technology and telecommunications. The main outcome of this project will be a…

Logistics Management: New trends in the Reverse Logistics

Science.gov (United States)

Antonyová, A.; Antony, P.; Soewito, B.

2016-04-01

Present level and quality of the environment are directly dependent on our access to natural resources, as well as their sustainability. In particular production activities and phenomena associated with it have a direct impact on the future of our planet. Recycling process, which in large enterprises often becomes an important and integral part of the production program, is usually in small and medium-sized enterprises problematic. We can specify a few factors, which have direct impact on the development and successful application of the effective reverse logistics system. Find the ways to economically acceptable model of reverse logistics, focusing on converting waste materials for renewable energy, is the task in progress.

REGIONAL LOGISTICS CENTER: FORMATION AND FUNCTIONING SPESIFIC

Directory of Open Access Journals (Sweden)

Oleg Tkach

2017-08-01

Full Text Available In this article the essence of the definition of logistics centers is defined, the main provisions concerning the formation of the logistics center are defined. The formation of a logistic hub is analyzed. The structure of the transport-logistic center is proposed. The basic requirements for the location of the regional logistics center and the principles of its operation are determined. The financial and financial mechanism of a typical logistics center and their effective functioning are presented. It is proved that the most important component of the logistics center is transport. Key words: logistics centers, logistics, hub, distribution centers, transport and logistics centers, regional logistic centers, logistics complex, transport, transport-logistic system.

Logistics innovation development

DEFF Research Database (Denmark)

Pedrosa, Alex; Blazevic, Vera; Jasmand, Claudia

2014-01-01

to investigate the role of boundary-spanning employees in deepening and broadening customer knowledge while developing logistics service innovations. Findings The results show that boundary-spanning employees’ engage sequentially in deepening and broadening customer knowledge throughout the logistics innovation...... development process. In particular it shows that deepening customer knowledge tends to occur in one-to-one interactions. When boundary-spanning employees engage in broadening customer knowledge, they develop a rich understanding of current customer. Research limitations/implications (if applicable) In general......Purpose This paper aims to investigate the microfoundations—boundary-spanning employees activities and behaviors—of deepening and broadening customer knowledge during logistics innovation development. Design/methodology/approach A multiple case study approach (six case studies) was adopted...

The logic of logistics theory, algorithms, and applications for logistics and supply chain management

CERN Document Server

Simchi-Levi, David; Bramel, Julien

2005-01-01

Fierce competition in today's global market provides a powerful motivation for developing ever more sophisticated logistics systems. This book, written for the logistics manager and researcher, presents a survey of the modern theory and application of logistics. The goal of the book is to present the state of the art in the science of logistics management. As a result, the authors have written a timely and authoritative survey of this field that many practitioners and researchers will find makes an invaluable companion to their work.

Measuring efficiency in logistics

Directory of Open Access Journals (Sweden)

Milan Milovan Andrejić

2013-06-01

Full Text Available Dynamic market and environmental changes greatly affect operating of logistics systems. Logistics systems have to realize their activities and processes in an efficient way. The main objective of this paper is to analyze different aspects of efficiency measurement in logistics and to propose appropriate models of measurement. Measuring efficiency in logistics is a complex process that requires consideration of all subsystems, processes and activities as well as the impact of various financial, operational, environmental, quality and other factors. The proposed models have a basis in the Data Envelopment Analysis method. They could help managers in decision making and corrective actions processes. The tests and results of the model show the importance of input and output variables selection.

International Production and Global Logistics Operations : Management Issues in Global Logistics with Offshored Production Systems

OpenAIRE

Korrmann, Franziska

2011-01-01

This paper is directed at discussing some of the management issues, problems and solutions of logistics in the context of offshored productive activities The introduction includes a discussion of the logistics topics and an introduction of the economic logic of offshoring. The main part analyses the logistics topics with regard to the internationally fragmented production. The topics of logistics include: Information flow and integration, transportation, inventory management, warehousing and ...

Logistic Fuel Processor Development

National Research Council Canada - National Science Library

Salavani, Reza

2004-01-01

The Air Base Technologies Division of the Air Force Research Laboratory has developed a logistic fuel processor that removes the sulfur content of the fuel and in the process converts logistic fuel...

Review on Doctoral Dissertation: Drago Pupavac: Logistics operator – the factor of dynamic optimization of global logistics chains

Directory of Open Access Journals (Sweden)

Ratko Zelenika

2007-05-01

Full Text Available The main objective of the scientific research of this doctoral thesis is the effect of the logistics operator in the function of cutting total costs of the global logistics chain. In order to achieve the objective of the research, a number of scientific methods have been applied such as survey methods, methods of dynamic programming and mixed convex programming. Owing to the applied scientific methodology,Drago Pupovac, M.Sc. has successfully interpreted the obtained results by proving that the selective model approach to active participants of the logistics chain gives the logistics operator the insight into potential logistics network, depicts skills of individual operators in the logistics network, specifies logistics activitiesof each logistics venture, provides information on costs of specific logistics activities and in that way proves that it enables logistics operator to optimize logistics chains by protecting them from the demand instability and changes.

The Emergence of City Logistics

DEFF Research Database (Denmark)

Gammelgaard, Britta; Aastrup, Jesper

2014-01-01

Purpose: Many city logistics projects in Europe have failed. The purpose of this article is to increase understanding of how city logistics emerge. A better understanding of the complex organizational processes with many actors and stakeholders in city logistics projects may prevent further failu...

Logistics, electronic commerce, and the environment

Science.gov (United States)

Sarkis, Joseph; Meade, Laura; Talluri, Srinivas

2002-02-01

Organizations realize that a strong supporting logistics or electronic logistics (e-logistics) function is important from both commercial and consumer perspectives. The implications of e-logistics models and practices cover the forward and reverse logistics functions of organizations. They also have direct and profound impact on the natural environment. This paper will focus on a discussion of forward and reverse e-logistics and their relationship to the natural environment. After discussion of the many pertinent issues in these areas, directions of practice and implications for study and research are then described.

A Study on Reverse Logistics

OpenAIRE

Reddy, Dhananjaya

2011-01-01

In the competitive world of manufacturing, companies are often searching for new ways to improve their process, customer satisfaction and stay ahead in the game with their competitors. Reverse logistics has been considered a strategy to bring these things to life for the past decade or so. This thesis work tries to shed some light on the basics of reverse logistics and how reverse logistics can be used as a management strategy. This paper points out the fundamentals of reverse logistics and l...

Logistics-production, logistics-marketing and external integration: Their impact on performance

OpenAIRE

Giménez, Cristina; Ventura, Eva

2003-01-01

Highly competitive environments are leading companies to implement Supply Chain Management (SCM) to improve performance and gain a competitive advantage. SCM involves integration, co-ordination and collaboration across organisations and throughout the supply chain. It means that SCM requires internal (intraorganisational) and external (interorganisational) integration. This paper examines the Logistics-Production and Logistics- Marketing interfaces and their relation with the external integra...

The Challenge of Moving from Performance Based Logistics to an Operational Logistics Framework

National Research Council Canada - National Science Library

Bryant, Russell E

2005-01-01

... and qualified forces for the combatant commanders of the 21st century. One focal area is within the logistics area of overall warfighter support, commonly referred to as performance based logistics (PBL...

Green Maritime Logistics

DEFF Research Database (Denmark)

Psaraftis, Harilaos N.

2014-01-01

Typical problems in maritime logistics include, among others, optimal ship speed, ship routing and scheduling, fleet deployment, fleet size and mix, weather routing, intermodal network design, modal split, transshipment, queuing at ports, terminal management, berth allocation, and total supply...... chain management. The traditional analysis of these problems has been in terms of cost- benefit and other optimization criteria from the point of view of the logistics provider, carrier, shipper, or other end-user. Such traditional analysis by and large either ignores environmental issues, or considers...... them of secondary importance. Green maritime logistics tries to bring the environmental dimension into the problem, and specifically the dimension of emissions reduction, by analyzing various trade-offs and exploring ‘win-win’ solutions. This talk takes a look at the trade-offs that are at stake...

Subset selection from generalized logistic populations

NARCIS (Netherlands)

Laan, van der M.J.; Laan, van der P.

1997-01-01

We give an introduction to the logistic and generalized logistic distributions. These generalized logistic distributions Type-I, Type-II and Type-III are indexed by a real valued parameter. They have been derived as mixtures with the standard logistic distribution and for discrete values of the

Challenges of Green Logistics in Southeast Europe

OpenAIRE

Beškovnik, Bojan; Jakomin, Livio

2010-01-01

This paper describes the trends towards green logistics in global aspect and challenges of adopting green logistics in the region of Southeast Europe. Modern logistics with supply chain management is experiencing a period of important evolution. From reversible logistics, we came to green logistics, which is a wider concept of environmentally friendly thinking. Reverse logistics includes processes of movements and transportation of waste from users to recycling plants; meanwhile, green logist...

Logistics service management; differentiating the logistics service

NARCIS (Netherlands)

Veeken, van der D.J.M.; Rutten, W.G.M.M.

1998-01-01

In this article a model is described, which enables differentiation of the logistics service that a company offers to its customers. Differentiating this service is essential for businesses with a large variation within their customer and/or products portfolio. The model consists of four phases:

The oral, live attenuated enterotoxigenic Escherichia coli vaccine ACE527 reduces the incidence and severity of diarrhea in a human challenge model of diarrheal disease.

Science.gov (United States)

Darsley, Michael J; Chakraborty, Subhra; DeNearing, Barbara; Sack, David A; Feller, Andrea; Buchwaldt, Charlotte; Bourgeois, A Louis; Walker, Richard; Harro, Clayton D

2012-12-01

An oral, live attenuated, three-strain recombinant bacterial vaccine, ACE527, was demonstrated to generate strong immune responses to colonization factor and toxin antigens of enterotoxigenic Escherichia coli (ETEC) in human volunteers. The vaccine was safe and well tolerated at doses of up to 10(11) CFU, administered in each of two doses given 21 days apart. These observations have now been extended in a phase 2b study with a total of 70 subjects. Fifty-six of these subjects were challenged 28 days after the second dose of vaccine with the highly virulent ETEC strain H10407 to obtain preliminary indicators of efficacy against disease and to support further development of the vaccine for both travelers and infants in countries where ETEC is endemic. The vaccine had a significant impact on intestinal colonization by the challenge strain, as measured by quantitative fecal culture 2 days after challenge, demonstrating the induction of a functional immune response to the CFA/I antigen. The incidence and severity of diarrhea were also reduced in vaccinees as measured by a number of secondary and ad hoc endpoints, although the 27% reduction seen in the primary endpoint, moderate to severe diarrhea, was not statistically significant. Together, these observations support the hypothesis that the ACE527 vaccine has a dual mode of action, targeting both colonization factors and the heat-labile enterotoxin (LT), and suggest that it should be further developed for more advanced trials to evaluate its impact on the burden of ETEC disease in field settings.

3PL Services in City Logistics

DEFF Research Database (Denmark)

Aastrup, Jesper; Gammelgaard, Britta; Prockl, Günter

2012-01-01

The purpose of this paper is 1) to develop an overview of activities and services that can add value for users and consignees in city logistics schemes based on Urban Consolidation Centre, and 2) to understand and analyze the perceived value for users and consignees from using such services....... The paper will be based on studies of the city logistics literature and existing city logistics schemes, as well as survey and interview findings from studies of potential users (retailers) in Copenhagen inner city and interviews with existing users (retailers) of existing city logistics services...... in the cities of Maastricht, Netherlands, and Hasselt, Belgium. The paper provides an overview and classification of possible third party logistics services in city logistics schemes. Also, findings about value perceived by current users as well as potential users are presented. Literature on city logistics has...

Analyzing the Dependency Between National Logistics Performance and Competitiveness: Which Logistics Competence is Core for National Strategy?

Directory of Open Access Journals (Sweden)

Burmaoglu Serhat

2011-12-01

Full Text Available With the advancements in the strategic management field, logistics management has changed considerably and logistics competency has emerged as a new and important area of research. In this regard, the purpose of this study is to find the core logistics abilities, which enable nations to achieve a competitive advantage in the logistics market. Two different data sets, one from World Economic Forum and the other from the World Bank were used. Cluster and discriminant analysis were used to answer the research questions. The results indicated that while the logistics infrastructure and the customs were absolute in determining a high-competitive country, the logistics competence and the tracking & tracing were the core logistics abilities needed to sustain the competitive advantage in long term. The implications of these results are also discussed.

dLOGIS: Disaster Logistics Information System

Science.gov (United States)

Koesuma, Sorja; Riantana, Rio; Siswanto, Budi; Aji Purnomo, Fendi; Lelono, Sarjoko

2017-11-01

There are three timing of disaster mitigation which is pre-disaster, emergency response and post-disaster. All of those is important in disaster mitigation, but emergency response is important when we are talking about time. Emergency response has limited time when we should give help. Rapid assessment of kind of logistic, the number of survivors, number children and old people, their gender and also for difable person. It should be done in emergency response time. Therefore we make a mobile application for logistics management system. The name of application is dLOGIS, i.e. Disaster Logistics Information System. The application is based on Android system for mobile phone. Otherwise there is also website version. The website version is for maintenance, data input and registration. So the people or government can use it directly when there is a disaster. After login in dLOGIS, there is five main menus. The first main menu shows disaster information, refugees conditions, logistics needed, available logistics stock and already accepted logistics. In the second menu is used for entering survivors data. The field coordinator can enter survivors data based on the rapid assessment in disaster location. The third menu is used for entering kind of logistic. Number and kind of logistics are based on the BNPB needed standard for the survivor. The fourth menu displays the logistics stock available in field coordinator. And the last menu displays the logistics help that already accepted and sent by donation. By using this application when a disaster happened, field coordinator or local government can use maintenance distribution of logistics base on their needs. Also for donor people who will give help to survivor, they can give logistics with the corresponding of survivor needs.

Behavioral Operations in Logistics

NARCIS (Netherlands)

J. de Vries (Jelle)

2016-01-01

markdownabstractIn the world of logistics, a considerable share of all work is automated and performed by machines or robots. An examination of the existing logistics research reflects this image, since a substantial share of the studies focus on automated processes, and perfectly predictable

3PL, 4PL and insourcing logistics

Directory of Open Access Journals (Sweden)

Mauro Vivaldini

2015-12-01

Full Text Available Logistics services have evolved and changed over time, especially in the hiring of them according to the concepts of 3PL (third party logistics, 4PL (fourth party logistics or insourcing logistics. 3PL service is a consolidated business, 4PL is an option for outsourcing logistics and has already been adopted by some organizations, and insourcing logistics suggests the return of these activities being internalized by companies, which is still a relatively unexplored subject in logistics literature. Analyzing these themes in the literature, this study updates the view on them and proposes a conceptual framework that classifies the different models of logistics services, showing the different options that can be adopted to help the company decide how to run their logistics services.

Country logistics performance and disaster impact.

Science.gov (United States)

Vaillancourt, Alain; Haavisto, Ira

2016-04-01

The aim of this paper is to deepen the understanding of the relationship between country logistics performance and disaster impact. The relationship is analysed through correlation analysis and regression models for 117 countries for the years 2007 to 2012 with disaster impact variables from the International Disaster Database (EM-DAT) and logistics performance indicators from the World Bank. The results show a significant relationship between country logistics performance and disaster impact overall and for five out of six specific logistic performance indicators. These specific indicators were further used to explore the relationship between country logistic performance and disaster impact for three specific disaster types (epidemic, flood and storm). The findings enhance the understanding of the role of logistics in a humanitarian context with empirical evidence of the importance of country logistics performance in disaster response operations. © 2016 The Author(s). Disasters © Overseas Development Institute, 2016.

Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative

Directory of Open Access Journals (Sweden)

Rachel G. Greenberg

2018-03-01

Of the 136 providers surveyed, 52/136 (38% had previously referred a pediatric patient to a trial, and only 17/136 (12% had ever been an investigator for a pediatric trial. Lack of awareness of existing pediatric trials was a major barrier to patient referral by providers, in addition to consideration of trial risks, distance to the site, and time needed to discuss trial participation with parents. Overall, providers perceived greater challenges related to parental concerns and parent or child logistical barriers than study implementation and ethics or regulatory barriers as barriers to their practice serving as a trial site. Providers who had previously been an investigator for a pediatric trial were less likely to be concerned with potential barriers than non-investigators. Understanding the barriers that limit pediatric providers from collaboration or inhibit their participation is key to designing effective interventions to optimize pediatric trial participation.

Logistics Collaboration between Shippers and Logistics Service Providers. Observations in the chemical industry

NARCIS (Netherlands)

Drs. Lenny Visser

2007-01-01

Summary Project objectives This study fits into a larger research project on logistics collaboration and outsourcing decisions. The final objective of this larger project is to analyze the logistics collaboration decision in more detail to identify thresholds in these decisions. To reach the

Efficiency and Logistics

CERN Document Server

Hompel, Michael; Klumpp, Matthias

2013-01-01

The „EffizienzCluster LogistikRuhr“ was a winner in the Leading Edge Science Cluster competition run by the German federal Ministry of Education and Research. The mission and aim of the „EffizienzCluster LogistikRuhr“ is to facilitate tomorrow’s individuality – in the sense of individual goods supply, mobility, and production – using 75 percent of today’s resources. Efficiency – both in economical and ecological terms – is enabled by state-of-the-art and innovative logistical solutions including transportation, production and intralogistics. These proceedings “Efficiency and Logistics” give first answers from 27 research projects as an insight into the current state of research of Europe’s leading research and development cluster in logistics and as a contribution to the discussion on how logistics as a science can help to cope with foreseeable resource shortage and sustainability as global challenges.

Logistic management materials-technical support railway enterprises

OpenAIRE

Dykan, V.; Borozenetc, T.

2014-01-01

The essence of logistics management. Determine the feasibility of applying the principles of logistics management in organizing the logistics of railway transport. Discussed measures to develop suppliers in the implementation of logistics management logistics. Identified the need to develop and implement regulatory and methodical system to improve materials-technical support through the introduction of modern logistics principles. Applied systemic campaign to organize the materials-technical ...

Reverse logistics policy – differences between conservative and innovative reverse logistics management

Directory of Open Access Journals (Sweden)

Alena Klapalová

2013-01-01

Full Text Available One of the of the key barriers that hampers effective and efficient management of reverse flows detected within a number of empirical surveys and case studies focused on reverse logistics and/or return management is business (organisational policy, specifically lack of policy, deficiency in existing policy or inferior policy. Despite this fact, there is a gap in literature which would show some evidence from practice that innovative reverse logistics policy both can pay off and is associated with certain aspects of reverse logistics management. Such proof can have several implications. It can support the call for better understanding and more research of the linkages of reverse logistics with other corporate functions, promote the acceptation of strategic character of reverse logistics and stress the role of RL policy within the rest of overall corporate management.The aim of this paper is to contribute and to enrich the existing body of knowledge concerning the above-mentioned gap through presentation of survey results that was realized in 2012 among managers of 244 Czech firms. The results demonstrate the statistically significant association between the innovativeness of RL policy and profitability of firms, quality of RL planning, perception of RL importance, level of RL knowledge and perception of product innovation importance for firms’ competitiveness and frequency of product innovation. They also reveal statistically significant differences between firms with conservative and innovative RL policy and the perceived existence of some barriers to manage RL.

Quality of investments in logistics

Directory of Open Access Journals (Sweden)

Borut Jereb

2014-06-01

Full Text Available The issue problem of paper is that base on researches connected with analysis of investments in logistics based on the review of 100 pooled manuscripts from different sources (scientific journals and online magazines from 1996 to 2012 it was showed that there don't exist quality as well as leadership has no a good overview of the investment in logistics. It was claimed that the quality point of view should be demanding part of investments in logistics. Val Log was proposed as an answer to the issues of managing quality of investments in logistics at the tactical level in organizations. By Val Log it is possible to overcome the myth that logistics projects cost money while business projects bring money. Val Log also provides detailed instructions for goals and metrics for each process. By doing changes the quality should be the obvious pillar of our affords doing it.

The Logistics Performance Effect in International Trade

Directory of Open Access Journals (Sweden)

Azmat Gani

2017-12-01

Full Text Available The continuous growth in world trade depends on the efficiency of trade support structures such as the logistics services. Despite logistics integral role in supporting commercial activities, there has generally been a low level of analysis and trade policy research focus from trade practitioners. This paper explores the effect of logistics performance in international trade. The analysis draws on overall logistics performance as well as disaggregated measures of logistics specificities data for a large sample of countries. The empirical analysis involved the estimation of standard export and import equations incorporating measures of logistics performance. The findings show that the overall logistics performance is positively and statistically significantly correlated with exports and imports. The analysis is also extended by investigating if logistics specificities mattered for international trade. The findings reveal that several dimensions capturing logistics performance have statistically significant and positive effect, mostly on exports. The main policy implication is that continuous investment in logistics infrastructure and services can positively impact international trade.

Comparative analysis of antimicrobial resistance in enterotoxigenic Escherichia coli isolates from two paediatric cohort studies in Lima, Peru.

Science.gov (United States)

Medina, Anicia M; Rivera, Fulton P; Pons, Maria J; Riveros, Maribel; Gomes, Cláudia; Bernal, María; Meza, Rina; Maves, Ryan C; Huicho, Luis; Chea-Woo, Elsa; Lanata, Claudio F; Gil, Ana I; Ochoa, Theresa J; Ruiz, Joaquim

2015-08-01

Antibiotic resistance is increasing worldwide, being of special concern in low- and middle-income countries. The aim of this study was to determine the antimicrobial susceptibility and mechanisms of resistance in 205 enterotoxigenic Escherichia coli (ETEC) isolates from two cohort studies in children Peru. ETEC were identified by an in-house multiplex real-time PCR. Susceptibility to 13 antimicrobial agents was tested by disk diffusion; mechanisms of resistance were evaluated by PCR. ETEC isolates were resistant to ampicillin (64%), cotrimoxazole (52%), tetracycline (37%); 39% of the isolates were multidrug-resistant. Heat-stable toxin producing (ETEC-st) (48%) and heat-labile toxin producing ETEC (ETEC-lt) (40%) had higher rates of multidrug resistance than isolates producing both toxins (ETEC-lt-st) (21%), pPeru. However, further development of resistance should be closely monitored. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

LOGISTICS MANAGEMENT IN THE CONTEMPORARY ECONOMY

Directory of Open Access Journals (Sweden)

Ion SARBU

2014-03-01

Full Text Available The evolution of logistics management as a system in the recent decades can be characterized by the influence of the globalization processes and the economic integration in the European Union. Systemic logistic approach ensured revolutionizing the optimization of the logistics chain. Logistics management must be given to permanent forms of the new legal and organizational structure appropriate to the contemporary economy.

LOGISTICS MANAGEMENT IN THE CONTEMPORARY ECONOMY

Directory of Open Access Journals (Sweden)

Ion SARBU

2014-01-01

Full Text Available The evolution of logistics management as a system in the recent decades can be characterized by the influence of the globalization processes and the economic integration in the European Union. Systemic logistic approach ensured revolutionizing the optimization of the logistics chain. Logistics management must be given to permanent forms of the new legal and organizational structure appropriate to the contemporary economy.

Improving Clinical Trial Efficiency: Thinking outside the Box.

Science.gov (United States)

Mandrekar, Sumithra J; Dahlberg, Suzanne E; Simon, Richard

2015-01-01

Clinical trial design strategies have evolved over the past few years as a means to accelerate the drug development process so that the right therapies can be delivered to the right patients. Basket, umbrella, and adaptive enrichment strategies represent a class of novel designs for testing targeted therapeutics in oncology. Umbrella trials include a central infrastructure for screening and identification of patients, and focus on a single tumor type or histology with multiple subtrials, each testing a targeted therapy within a molecularly defined subset. Basket trial designs offer the possibility to include multiple molecularly defined subpopulations, often across histology or tumor types, but included in one cohesive design to evaluate the targeted therapy in question. Adaptive enrichment designs offer the potential to enrich for patients with a particular molecular feature that is predictive of benefit for the test treatment based on accumulating evidence from the trial. This review will aim to discuss the fundamentals of these design strategies, the underlying statistical framework, the logistical barriers of implementation, and, ultimately, the interpretation of the trial results. New statistical approaches, extensive multidisciplinary collaboration, and state of the art data capture technologies are needed to implement these strategies in practice. Logistical challenges to implementation arising from centralized assay testing, requirement of multiple specimens, multidisciplinary collaboration, and infrastructure requirements will also be discussed. This review will present these concepts in the context of the National Cancer Institute's precision medicine initiative trials: MATCH, ALCHEMIST, Lung MAP, as well as other trials such as FOCUS4.

Logistic regression applied to natural hazards: rare event logistic regression with replications

Science.gov (United States)

Guns, M.; Vanacker, V.

2012-06-01

Statistical analysis of natural hazards needs particular attention, as most of these phenomena are rare events. This study shows that the ordinary rare event logistic regression, as it is now commonly used in geomorphologic studies, does not always lead to a robust detection of controlling factors, as the results can be strongly sample-dependent. In this paper, we introduce some concepts of Monte Carlo simulations in rare event logistic regression. This technique, so-called rare event logistic regression with replications, combines the strength of probabilistic and statistical methods, and allows overcoming some of the limitations of previous developments through robust variable selection. This technique was here developed for the analyses of landslide controlling factors, but the concept is widely applicable for statistical analyses of natural hazards.

Logistic regression models

CERN Document Server

Hilbe, Joseph M

2009-01-01

This book really does cover everything you ever wanted to know about logistic regression … with updates available on the author's website. Hilbe, a former national athletics champion, philosopher, and expert in astronomy, is a master at explaining statistical concepts and methods. Readers familiar with his other expository work will know what to expect-great clarity.The book provides considerable detail about all facets of logistic regression. No step of an argument is omitted so that the book will meet the needs of the reader who likes to see everything spelt out, while a person familiar with some of the topics has the option to skip "obvious" sections. The material has been thoroughly road-tested through classroom and web-based teaching. … The focus is on helping the reader to learn and understand logistic regression. The audience is not just students meeting the topic for the first time, but also experienced users. I believe the book really does meet the author's goal … .-Annette J. Dobson, Biometric...

Macro-institutional Complexity in Logistics

DEFF Research Database (Denmark)

Wessel, Frederic; Kinra, Aseem; Kotzab, Herbert

2016-01-01

structure and transactional costs, the concept of environmental complexity is applied to the logistics management perspective. Thereby, the impacts which a given framework on a macro-institutional level might have on the situation and leeway in decision-making at the firm (micro) or the supply chain (meso......In this paper, the interlink between the concept of macro-institutional complexity in logistics and the dynamics in the logistics practice of Eastern Europe will be examined. Referring to the importance of different authors having ascribed to the external environmental uncertainty on organizational......) levels will be analysed. Furthermore, a quantitative modelling approach will be presented and exemplified by using the case of logistics infrastructure in Eastern Europe....

Genotypic and Phenotypic Characterization of Enterotoxigenic Escherichia coli Strains Isolated from Peruvian Children ▿

Science.gov (United States)

Rivera, F. P.; Ochoa, T. J.; Maves, R. C.; Bernal, M.; Medina, A. M.; Meza, R.; Barletta, F.; Mercado, E.; Ecker, L.; Gil, A. I.; Hall, E. R.; Huicho, L.; Lanata, C. F.

2010-01-01

Enterotoxigenic Escherichia coli (ETEC) is a major cause of childhood diarrhea. The present study sought to determine the prevalence and distribution of toxin types, colonization factors (CFs), and antimicrobial susceptibility of ETEC strains isolated from Peruvian children. We analyzed ETEC strains isolated from Peruvian children between 2 and 24 months of age in a passive surveillance study. Five E. coli colonies per patient were studied by multiplex real-time PCR to identify ETEC virulence factors. ETEC-associated toxins were confirmed using a GM1-based enzyme-linked immunosorbent assay. Confirmed strains were tested for CFs by dot blot assay using 21 monoclonal antibodies. We analyzed 1,129 samples from children with diarrhea and 744 control children and found ETEC in 5.3% and 4.3%, respectively. ETEC was more frequently isolated from children >12 months of age than from children <12 months of age (P < 0.001). Fifty-two percent of ETEC isolates from children with diarrhea and 72% of isolates from controls were heat-labile enterotoxin (LT) positive and heat-stable enterotoxin (ST) negative; 25% and 19%, respectively, were LT negative and ST positive; and 23% and 9%, respectively, were LT positive and ST positive. CFs were identified in 64% of diarrheal samples and 37% of control samples (P < 0.05). The most common CFs were CS6 (14% and 7%, respectively), CS12 (12% and 4%, respectively), and CS1 (9% and 4%, respectively). ST-producing ETEC strains caused more severe diarrhea than non-ST-producing ETEC strains. The strains were most frequently resistant to ampicillin (71%) and co-trimoxazole (61%). ETEC was thus found to be more prevalent in older infants. LT was the most common toxin type; 64% of strains had an identified CF. These data are relevant in estimating the burden of disease due to ETEC and the potential coverage of children in Peru by investigational vaccines. PMID:20631096

Efficacy of a single oral dose of a live bivalent E. coli vaccine against post-weaning diarrhea due to F4 and F18-positive enterotoxigenic E. coli.

Science.gov (United States)

Nadeau, É; Fairbrother, J M; Zentek, J; Bélanger, L; Tremblay, D; Tremblay, C-L; Röhe, I; Vahjen, W; Brunelle, M; Hellmann, K; Cvejić, D; Brunner, B; Schneider, C; Bauer, K; Wolf, R; Hidalgo, Á

2017-08-01

F4- and F18-positive enterotoxigenic E. coli strains (F4-ETEC and F18-ETEC) are important causes of post-weaning diarrhea (PWD) in pigs. F4 (antigenic variant ac) and F18 (ab and ac) fimbriae are major antigens that play an important role in the early stages of infection. Herein, the efficacy of a live oral vaccine consisting of two non-pathogenic E. coli strains, one F4ac- and one F18ac-positive, was evaluated using F4ac-ETEC and F18ab-ETEC challenge models. A randomized, masked, placebo-controlled, block design, parallel-group confirmatory study with two different vaccination-challenge intervals (7 and 21 days) was conducted for each challenge model. The vaccine was administered in one dose, to ≥18-day-old piglets via drinking water. Efficacy was assessed by evaluating diarrhea, clinical observations, weight gain and fecal shedding of F4-ETEC or F18-ETEC. Anti-F4 and anti-F18 immunoglobulins in blood were measured. The vaccination resulted in significant reductions in clinical PWD and fecal shedding of F4-ETEC and F18-ETEC after the 7- and 21-day-post-vaccination heterologous challenges, except for after the 21-day-post-vaccination F4-ETEC challenge, when the clinical PWD was too mild to demonstrate efficacy. A significant reduction of mortality and weight loss by vaccination were observed following the F18-ETEC challenge. The 7-day protection was associated with induction of anti-F4 and anti-F18 IgM, whereas the 21-day protection was mainly associated with anti-F4 and anti-F18 IgA. The 7-day onset and 21-day duration of protection induced by this vaccine administered once in drinking water to pigs of at least 18days of age were confirmed by protection against F4-ETEC and F18-ETEC, and induction of F4 and F18-specific immunity. Cross protection of the vaccine against F18ab-E. coli was demonstrated for both the 7- and 21-day F18-ETEC challenges. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Outsourcing Operational Logistics: Buyer Beware

Science.gov (United States)

2003-05-16

This logistics system takes far too many people to conduct support missions and does not provide the desired customer performance in terms of...FINAL 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER OUTSOURCING OPERATIONAL LOGISTICS: BUYER BEWARE (U) 5b. GRANT NUMBER 5c...Form 298 (Rev. 8-98) 1 (Unclassified Paper) NAVAL WAR COLLEGE Newport, R.I. OUTSOURCING OPERATIONAL LOGISTICS: BUYER BEWARE By LAMONT WOODY Lieutenant

Logistic regression applied to natural hazards: rare event logistic regression with replications

Directory of Open Access Journals (Sweden)

M. Guns

2012-06-01

Full Text Available Statistical analysis of natural hazards needs particular attention, as most of these phenomena are rare events. This study shows that the ordinary rare event logistic regression, as it is now commonly used in geomorphologic studies, does not always lead to a robust detection of controlling factors, as the results can be strongly sample-dependent. In this paper, we introduce some concepts of Monte Carlo simulations in rare event logistic regression. This technique, so-called rare event logistic regression with replications, combines the strength of probabilistic and statistical methods, and allows overcoming some of the limitations of previous developments through robust variable selection. This technique was here developed for the analyses of landslide controlling factors, but the concept is widely applicable for statistical analyses of natural hazards.

A Theoretic Model of Transport Logistics Demand

OpenAIRE

Natalija Jolić; Nikolina Brnjac; Ivica Oreb

2006-01-01

Concerning transport logistics as relation between transportand integrated approaches to logistics, some transport and logisticsspecialists consider the tenn tautological. However,transport is one of the components of logistics, along with inventories,resources, warehousing, infonnation and goods handling.Transport logistics considers wider commercial and operationalframeworks within which the flow of goods is plannedand managed. The demand for transport logistics services canbe valorised as ...

Logistics potentials in business competitive advantage creation

Directory of Open Access Journals (Sweden)

Rafał Matwiejczuk

2013-12-01

Full Text Available Background: Companies constantly search for ways to achieve and sustain long-term competitive advantage. Among the factors influencing the competitive advantage creation there are so called logistics potentials, which constitute a component part of a business strategic potentials. Logistics resources, logistics capabilities and logistics competences are the main components of the logistics potentials structure and hierarchy. Methods: In order to recognize the logistics potentials which determine the competitive advantage creation one may use the assumptions and elements of contemporary management concepts, including strategic management. In particular the article deals with Resource-Based View (RBV, Dynamic Capabilities Concept (DCC and - first of all - Competence-Based Management (CBM. Results and conclusions: Several significant research projects have presented a wide scope and a large number of possibilities of logistics potentials (and logistics competences in particular influence on business competitive advantage creation. The article briefly presents the research results conducted by: (1 Michigan State University (USA, (2 European Logistics Association (ELA in cooperation with A.T. Kearney, (3 Computer Sciences Corporation and (4 Capgemini. The research results have pointed out to differentiated but at the same distinctive symptoms of logistics competences influence on competitive advantage creation. The article also refers to the results of the research carried out by the Chair of Logistics & Marketing at Opole University (Poland in companies operating in Poland. The research has been mainly dealing with the significance of logistics competences in competitive advantage creation.

Combining or Separating Forward and Reverse Logistics

DEFF Research Database (Denmark)

Herbert-Hansen, Zaza Nadja Lee; Larsen, Samuel; Nielsen, Anders

2018-01-01

Purpose – While forward logistics handles and manages the flow of goods downstream in the supply chain from suppliers to customers, reverse logistics (RL) manages the flow of returned goods upstream. A firm can combine reverse logistics with forward logistics, keep the flows separated, or choose......-research addresses intra-RL issues while the relationship between forward and reverse logistics is under-researched. This paper contributes to RL-theory by identifying the contextual factors that determine the most advantageous relationship between forward and reverse logistics, and proposes a novel decision making...

Outsourcing of Logistics Activities in Manufacturing Industry

Directory of Open Access Journals (Sweden)

Anton Ogorelc

2012-10-01

Full Text Available The external supply of logistics se1vices is part of a trend towardoutsourcing non-core logistics activities. The scope ofthird-party logistics may range from a relatively limited combinationof activities (e.g. transportation and warehousing to acomprehensive set of logistics se1vices.The authors first discuss the characteristics of business logisticsin manufacturing indusfly, to be taken into account inlogistics outsourcing. They particularly point out the motimtionsfor logistics outsourcing, the possibilities of outsourcing,as well as supplier selection. Finally they analyze the outsourcingin the reverse logistics.

Fungible weights in logistic regression.

Science.gov (United States)

Jones, Jeff A; Waller, Niels G

2016-06-01

In this article we develop methods for assessing parameter sensitivity in logistic regression models. To set the stage for this work, we first review Waller's (2008) equations for computing fungible weights in linear regression. Next, we describe 2 methods for computing fungible weights in logistic regression. To demonstrate the utility of these methods, we compute fungible logistic regression weights using data from the Centers for Disease Control and Prevention's (2010) Youth Risk Behavior Surveillance Survey, and we illustrate how these alternate weights can be used to evaluate parameter sensitivity. To make our work accessible to the research community, we provide R code (R Core Team, 2015) that will generate both kinds of fungible logistic regression weights. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Outsourcing Logistics Activities: Evidence from Slovenia

Directory of Open Access Journals (Sweden)

Klemen Kavčič

2016-12-01

Full Text Available The purpose of this research is to investigate how logistics outsourcing performs activities that have been traditionally carried out within the outsourcer’s company. The study examines the characteristics of logistics and transport services, which are important in cooperation with service providers. Two groups were formed according to the average values of the characteristics of logistics activities. ‘Cost, quality and response’ are important for the first group, while ‘logistics, environment and the ability to adapt to client processes’ are important for the second group. The results of the survey carried out in Slovenian enterprises show that both groups are primarily interested in express freight and shipment services, the difference lying in the understanding of logistics, mutual trust and brand recognition. The findings will be useful both in business practice and for managers, providing them with a better understanding of the performance of logistics outsourcing.

Content Marketing Plan for Logistics Company : Case: NetLogistic JVM Oy

OpenAIRE

Riabochkina, Elizaveta

2017-01-01

This project aim is to create a Content Marketing Strategy for a Finnish logistics company. The aim of the thesis is to develop an action plan that will help the commissioning company increase sales and gain new customers. The commissioner for the study is NetLogistic JVM Oy. The Company specializes in handling trade of transit and export shipments to Russia and CIS-countries via Finland. The company does not have huge resources to run large campaign, but is looking for ways to reach new...

The Art and Science of Defense Logistics

Science.gov (United States)

1995-04-01

The Art And Science Of Defense Logistics CSC 1995 SUBJECT AREA - Logistics THE ART AND SCIENCE OF DEFENSE LOGISTICS...Government EXECUTIVE SUMMARY Title: The Art and Science of Defense Logistics Author: Major S. I. Schuler, USMC Research Questions: 1...00-1995 4. TITLE AND SUBTITLE The Art And Science Of Defense Logistics 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6

Logistics Reduction Technologies for Exploration Missions

Science.gov (United States)

Broyan, James L., Jr.; Ewert, Michael K.; Fink, Patrick W.

2014-01-01

Human exploration missions under study are limited by the launch mass capacity of existing and planned launch vehicles. The logistical mass of crew items is typically considered separate from the vehicle structure, habitat outfitting, and life support systems. Although mass is typically the focus of exploration missions, due to its strong impact on launch vehicle and habitable volume for the crew, logistics volume also needs to be considered. NASA's Advanced Exploration Systems (AES) Logistics Reduction and Repurposing (LRR) Project is developing six logistics technologies guided by a systems engineering cradle-to-grave approach to enable after-use crew items to augment vehicle systems. Specifically, AES LRR is investigating the direct reduction of clothing mass, the repurposing of logistical packaging, the use of autonomous logistics management technologies, the processing of spent crew items to benefit radiation shielding and water recovery, and the conversion of trash to propulsion gases. Reduction of mass has a corresponding and significant impact to logistical volume. The reduction of logistical volume can reduce the overall pressurized vehicle mass directly, or indirectly benefit the mission by allowing for an increase in habitable volume during the mission. The systematic implementation of these types of technologies will increase launch mass efficiency by enabling items to be used for secondary purposes and improve the habitability of the vehicle as mission durations increase. Early studies have shown that the use of advanced logistics technologies can save approximately 20 m(sup 3) of volume during transit alone for a six-person Mars conjunction class mission.

The spatial dimension of cycle logistics

Directory of Open Access Journals (Sweden)

Luca Staricco

2016-08-01

Full Text Available Cycle logistics is emerging as a promising alternative in urban freight transport. Compared to fossil fuelled vans, the use of cycles for delivering goods within urban areas offers advantages in terms of environmental friendliness, economic efficiency, flexibility, and liveability of urban neighbourhood. At the same time, cycle logistics has to face limits in terms of weight and volume of goods that can be delivered, distances that can be covered, and spatial urban structures that can be served. This latter issue has till now received less attention in the scientific literature: it is generally recognized that cycle logistics performs at its best in inner urban areas, but no systematic study has been realized to identify specific spatial requisites for the effectiveness of cycle logistics. This paper provides a brief review of the main issues that emerge from the literature over cycle logistics, and contributes to stimulate the debate over the spatial dimension of cycle logistics: it presents a classification of cycle logistics schemes, on the basis of their integration with other urban logistic facilities and of the spatial structure of delivery operations. A three-level classification is proposed, depending on the type of goods consolidation: only distribution without consolidation, consolidation in a fixed urban consolidation centre, or consolidation in a mobile depot; for each level, operational examples and case studies are provided. This systematizing typology could support both public and private operators in decisions about the organization of cycle logistics facilities, such as the location of urban consolidation centres or the composition of cycle fleets.

Logistics in Namibia: Issues and challenges

Directory of Open Access Journals (Sweden)

Christopher J. Savage

2013-08-01

Full Text Available Logistics is perceived to be important for Namibia’s growth and development, but this may be a matter of conjecture as there is a dearth of documented information about the industry in Namibia. Furthermore, it is uncertain what the understanding of logistics is for key stakeholders in the country. This article reports on a project; the objectives were to address some of these issues and to lay the foundation for a more thorough investigation in the future. The findings of the initial project were disseminated in 2012 by: a conference paper showing the challenges and opportunities facing logistics in Namibia in 2012; a report; and through a Logistics and Transport Workshop held in Walvis Bay, Namibia in September 2012. These reports, additional interviews and subsequent discussions highlighted some potential opportunities and problems. This article summarises the project to date, showing the methodology and findings as updated by subsequent feedback and further interviews. The findings from key stakeholders of the logistics industry in Namibia include: universal agreement on the importance of logistics to Namibia; the variety in the understanding of the term logistics; the strength of the continuing influence of South Africa as the dominant economic power in southern Africa; and contrasting views on the main factors limiting logistics development, including infrastructure, attitude, government, customs, training, railways, corruption and driver shortage.

FUTURE CIRCULAR COLLIDER LOGISTICS STUDY

CERN Document Server

Beißert, Ulrike; Kuhlmann, Gerd; Nettsträter, Andreas; Prasse, Christian; Wohlfahrt, Andreas

2018-01-01

The Large Hadron Collider (LHC) at the European Organization for Nuclear Research CERN in Geneva is the largest and most powerful collider in the world. CERN and its research and experimental infrastructure is not only a focus for the science community but is also very much in the public eye. With the Future Circular Collider (FCC) Study, CERN has begun to examine the feasibility of a new underground accelerator ring with a length of approximately 100 kilometres. Logistics is of great importance for the construction, assembly and operation of the FCC. During the planning, construction and assembly of the LHC, logistics proved to be one of the key factors. As the FCC is even larger than the LHC, logistics will also become more and more significant. This report therefore shows new concepts, methods and analytics for logistics, supply chain and transport concepts as part of the FCC study. This report deals with three different logistics aspects for the planning and construction phase of FCC: 1. A discussion of d...

NASA Space Rocket Logistics Challenges

Science.gov (United States)

Neeley, James R.; Jones, James V.; Watson, Michael D.; Bramon, Christopher J.; Inman, Sharon K.; Tuttle, Loraine

2014-01-01

The Space Launch System (SLS) is the new NASA heavy lift launch vehicle and is scheduled for its first mission in 2017. The goal of the first mission, which will be uncrewed, is to demonstrate the integrated system performance of the SLS rocket and spacecraft before a crewed flight in 2021. SLS has many of the same logistics challenges as any other large scale program. Common logistics concerns for SLS include integration of discreet programs geographically separated, multiple prime contractors with distinct and different goals, schedule pressures and funding constraints. However, SLS also faces unique challenges. The new program is a confluence of new hardware and heritage, with heritage hardware constituting seventy-five percent of the program. This unique approach to design makes logistics concerns such as commonality especially problematic. Additionally, a very low manifest rate of one flight every four years makes logistics comparatively expensive. That, along with the SLS architecture being developed using a block upgrade evolutionary approach, exacerbates long-range planning for supportability considerations. These common and unique logistics challenges must be clearly identified and tackled to allow SLS to have a successful program. This paper will address the common and unique challenges facing the SLS programs, along with the analysis and decisions the NASA Logistics engineers are making to mitigate the threats posed by each.

END-OF-USE PRODUCTS IN REVERSE LOGISTICS

OpenAIRE

Marta Starostka-Patyk

2007-01-01

Reverse logistics is a very useful tool for enterprises which have to deal with end-of-use products. Forward logistics is not able to manage them, because they show up on the beginning of reverse supply chain. That is the reason for growing importance of reverse flows. Reverse logistics is quite new logistics system. This paper presents the idea of reverse logistics and end-of-use products problems.

STUDY OF THE STATE OF LOGISTICS IN KAZAKHSTAN: PROSPECTS FOR DEVELOPMENT AND DEPLOYMENT OF TRANSPORT AND LOGISTICS CENTRES

Directory of Open Access Journals (Sweden)

Zhanarys RAIMBEKOV

2016-12-01

Full Text Available The creation and development of Kazakhstan as a trade, logistics and business hub of the region is on the agenda of the Government of Kazakhstan. To achieve this, central and local governments, private businesses invest in new infrastructure projects in logistics. The article investigates the problems of modern logistics infrastructure formation in the territory of the Republic of Kazakhstan. The survey results show that the attractiveness of Kazakhstan as a transport and logistics hub will depend on the state of logistics infrastructure, service quality, and technology used. Further development will largely depend on its ability to diversify and create logistics facilities with high added value. Priorities and the need for multi-level transport logistic centres have been defined; their development in domestic, export and transit directions has been described, both at the national and international levels and at the enterprise level as well.

Halal logistics: A marketing mix perspective

Directory of Open Access Journals (Sweden)

Abu Bakar Abdul Hamid

2014-12-01

Full Text Available Ḥalāl is no longer understood as solely concerning food consumption or ritual slaughter. It is at the centre of the global Muslim food industry and logistics is one of its driving forces. The growing demand for ḥalāl food integrity contributes to the need for ḥalāl logistics. However, ḥalāl logistics operation has thus far not been warmly received by the industry thus hampering the availability of such services. This conceptual study attempts to illuminate the issue by addressing ḥalāl logistics from a marketing perspective. The concept of marketing mix and how it can be practiced by industrial players in marketing or promoting ḥalāl logistics services underpins our discussion. Existing literature is reviewed and discussed to ascertain the link between ḥalāl logistics and the 7Ps of its marketing mix, namely, product, place, price, promotion, people, process, and programme.

E-LOGISTICS – MULTIMODAL TRANSPORT MANAGEMENT

Directory of Open Access Journals (Sweden)

Marcel LITRA

2013-05-01

Full Text Available The paper presents the role and the importance of logistics for products and services inorder to obtain the competitive advantage. After a short presentation of logistics evolution, we moveon to defining the logistics concept, respectively integrated logistics. The analysis of the logisticsactivities is based on the total cost concept and it has as a purpose the efficient and effectivemanagement of the physical flows of raw materials, materials and finite products, and of theinternational flows. The competitive advantage is ensured through the harmonization of the logisticsfunction with the other functions of the company and through the integration of the logistics chain ofall upstream and downstream organizations in order to ensure a high level of consumer service ateconomical costs under the farm of supply chain management. In the end we present the maintendencies in the evolution of logistics in the Romanian firms under the circumstances of the increaseof their international dimension.

A logistics professional

International Nuclear Information System (INIS)

Jaeaeskelaeinen, A.

1998-01-01

Finland's oil, chemicals, and energy company, Neste, has achieved an enviable standard of logistics serving the markets around the Baltic Rim. Neste's safe and efficient transportation services are handled by its own fleet of tankers, time-chartered vessels, contract road tankers, and rail. Neste's terminals play an important part in the company's logistics network. The company operates four terminals of its own in Finland, and works with other oil companies at three of their terminals. Neste's own terminals are located at the company's refineries at Porvoo and Naantali, and at Kokkola and Kemi on the Gulf of Bothnia. Outside Finland the completion of a new terminal at Riga in Latvia, to enhance the logistics services provided to Neste's network of service stations and direct sales customers in the Baltic countries. This joins a terminal at Muuga near Tallinn in Estonia, which has been operational for some five years. Construction work began on a terminal in St. Petersburg in December 1997 to serve customers in the St. Petersburg and Vyborg areas. Completion is scheduled for autumn 1999

Fermented soya bean (tempe) extracts reduce adhesion of enterotoxigenic Escherichia coli to intestinal epithelial cells.

Science.gov (United States)

Roubos-van den Hil, P J; Nout, M J R; Beumer, R R; van der Meulen, J; Zwietering, M H

2009-03-01

This study aimed to investigate the effect of processed soya bean, during the successive stages of tempe fermentation and different fermentation times, on adhesion of enterotoxigenic Escherichia coli (ETEC) K88 to intestinal brush border cells as well as Caco-2 intestinal epithelial cells; and to clarify the mechanism of action. Tempe was prepared at controlled laboratory scale using Rhizopus microsporus var. microsporus as the inoculum. Extracts of raw, soaked and cooked soya beans reduced ETEC adhesion to brush border cells by 40%. Tempe extracts reduced adhesion by 80% or more. ETEC adhesion to Caco-2 cells reduced by 50% in the presence of tempe extracts. ETEC K88 bacteria were found to interact with soya bean extracts, and this may contribute to the observed decrease of ETEC adhesion to intestinal epithelial cells. Fermented soya beans (tempe) reduce the adhesion of ETEC to intestinal epithelial cells of pig and human origin. This reduced adhesion is caused by an interaction between ETEC K88 bacteria and soya bean compounds. The results strengthen previous observations on the anti-diarrhoeal effect of tempe. This effect indicates that soya-derived compounds may reduce adhesion of ETEC to intestinal cells in pigs as well as in humans and prevent against diarrhoeal diseases.

Methodical approach to financial stimulation of logistics managers

Directory of Open Access Journals (Sweden)

Melnykova Kateryna V.

2014-01-01

Full Text Available The article offers a methodical approach to financial stimulation of logistics managers, which allows calculation of the incentive amount with consideration of profit obtained from introduction of optimisation logistics solutions. The author generalises measures, which would allow increase of stimulation of labour of logistics managers by the enterprise top managers. The article marks out motivation factors, which exert influence upon relation of logistics managers to execution of optimisation logistical solutions, which minimise logistical costs. The author builds a scale of financial encouragement for introduction of optimisation logistical solutions proposed by logistics managers. This scale is basic for functioning of the encouragement system and influences the increase of efficiency of logistics managers operation and also optimisation of enterprise logistical solutions.

Logistics in smallpox: the legacy.

Science.gov (United States)

Wickett, John; Carrasco, Peter

2011-12-30

Logistics, defined as "the time-related positioning of resources" was critical to the implementation of the smallpox eradication strategy of surveillance and containment. Logistical challenges in the smallpox programme included vaccine delivery, supplies, staffing, vehicle maintenance, and financing. Ensuring mobility was essential as health workers had to travel to outbreaks to contain them. Three examples illustrate a range of logistic challenges which required imagination and innovation. Standard price lists were developed to expedite vehicle maintenance and repair in Bihar, India. Innovative staffing ensured an adequate infrastructure for vehicle maintenance in Bangladesh. The use of disaster relief mechanisms in Somalia provided airlifts, vehicles and funding within 27 days of their initiation. In contrast the Expanded Programme on Immunization (EPI) faces more complex logistical challenges. Copyright © 2011 Elsevier Ltd. All rights reserved.

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 2: OSSA integrated logistics support strategy

Science.gov (United States)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

The purpose is to outline an Office of Space Science and Applications (OSSA) integrated logistics support strategy that will ensure effective logistics support of OSSA payloads at an affordable life-cycle cost. Program objectives, organizational relationships, and implementation of the logistics strategy are discussed.

Cost Calculation Model for Logistics Service Providers

Directory of Open Access Journals (Sweden)

Zoltán Bokor

2012-11-01

Full Text Available The exact calculation of logistics costs has become a real challenge in logistics and supply chain management. It is essential to gain reliable and accurate costing information to attain efficient resource allocation within the logistics service provider companies. Traditional costing approaches, however, may not be sufficient to reach this aim in case of complex and heterogeneous logistics service structures. So this paper intends to explore the ways of improving the cost calculation regimes of logistics service providers and show how to adopt the multi-level full cost allocation technique in logistics practice. After determining the methodological framework, a sample cost calculation scheme is developed and tested by using estimated input data. Based on the theoretical findings and the experiences of the pilot project it can be concluded that the improved costing model contributes to making logistics costing more accurate and transparent. Moreover, the relations between costs and performances also become more visible, which enhances the effectiveness of logistics planning and controlling significantly

Use of generalized ordered logistic regression for the analysis of multidrug resistance data.

Science.gov (United States)

Agga, Getahun E; Scott, H Morgan

2015-10-01

Statistical analysis of antimicrobial resistance data largely focuses on individual antimicrobial's binary outcome (susceptible or resistant). However, bacteria are becoming increasingly multidrug resistant (MDR). Statistical analysis of MDR data is mostly descriptive often with tabular or graphical presentations. Here we report the applicability of generalized ordinal logistic regression model for the analysis of MDR data. A total of 1,152 Escherichia coli, isolated from the feces of weaned pigs experimentally supplemented with chlortetracycline (CTC) and copper, were tested for susceptibilities against 15 antimicrobials and were binary classified into resistant or susceptible. The 15 antimicrobial agents tested were grouped into eight different antimicrobial classes. We defined MDR as the number of antimicrobial classes to which E. coli isolates were resistant ranging from 0 to 8. Proportionality of the odds assumption of the ordinal logistic regression model was violated only for the effect of treatment period (pre-treatment, during-treatment and post-treatment); but not for the effect of CTC or copper supplementation. Subsequently, a partially constrained generalized ordinal logistic model was built that allows for the effect of treatment period to vary while constraining the effects of treatment (CTC and copper supplementation) to be constant across the levels of MDR classes. Copper (Proportional Odds Ratio [Prop OR]=1.03; 95% CI=0.73-1.47) and CTC (Prop OR=1.1; 95% CI=0.78-1.56) supplementation were not significantly associated with the level of MDR adjusted for the effect of treatment period. MDR generally declined over the trial period. In conclusion, generalized ordered logistic regression can be used for the analysis of ordinal data such as MDR data when the proportionality assumptions for ordered logistic regression are violated. Published by Elsevier B.V.

THEORETICAL FRAMES FOR DESIGNING REVERSE LOGISTICS PROCESSES

OpenAIRE

Janusz K. Grabara; Sebastian Kot

2009-01-01

Logistics processes of return flow became more and more important in present business practice. Because of better customer satisfaction, environmental and financial aspects many enterprises deal with reverse logistics performance. The paper is a literature review focused on the design principles of reverse logistics processes Keywords: reverse logistics, designing.

Outsourcing of Transport and Logistics Services

Directory of Open Access Journals (Sweden)

Anton Ogorelc

2007-11-01

Full Text Available The author presents the results of the research in five parts,which are interconnected. After the introduction, in part two,entitled A Framework for Logistics Outsourcing Decisions,theoretical characteristics of outsourcing are presented. Partthree, Core Competences and Outsourcing, describes the logisticscompetences. Part 4, Transp011 and Logistics Outsourcingin Europe, discusses the trends in logistics development andoutsourcing. The paper will assist managers responsible for thedevelopment of logistics strategies. The paper offers a uniquebuyer-supplier pwtnership framework by proposing that the logisticsoutsourcing will increase the competitive advantage ofmanufacturing firms.

Key Trends Shaping the Global Logistics Environment

DEFF Research Database (Denmark)

Handfield, Robert; Straube, Frank; Pfohl, Hans-Christian

A summary from the full study “Trends and Strategies in Logistics and Supply Chain Management. Embracing Global Logistics Complexity to Drive Market Advantage” (2013).......A summary from the full study “Trends and Strategies in Logistics and Supply Chain Management. Embracing Global Logistics Complexity to Drive Market Advantage” (2013)....

76 FR 54468 - Petra Pet, Inc. (a/k/a Petrapport) v. Panda Logistics Limited; Panda Logistics Co., Ltd. (f/k/a...

Science.gov (United States)

2011-09-01

... Logistics Limited; Panda Logistics Co., Ltd. (f/k/a panda Int'l Transportation Co., Ltd.); and RDM Solutions... ``Complainant,'' against Respondents Panda Logistics Limited, Panda Logistics Co., Ltd. (f/k/a Panda Int'l... alleges that Respondents Panda Logistics Limited and Panda Logistics Co., Ltd., are each a non-vessel...

Logistics hardware and services control system

Science.gov (United States)

Koromilas, A.; Miller, K.; Lamb, T.

1973-01-01

Software system permits onsite direct control of logistics operations, which include spare parts, initial installation, tool control, and repairable parts status and control, through all facets of operations. System integrates logistics actions and controls receipts, issues, loans, repairs, fabrications, and modifications and assets in predicting and allocating logistics parts and services effectively.

Building Combat Strength through Logistics: Translating the New Air Force Logistics Concept of Operations into Action

Science.gov (United States)

1988-03-31

wholesale logistics systems. Rapid reprogramming , priority distribution and repair of critical logistics resources, regional logistics control networks, and...between the id, the ego, and th- superego. Ideals impact conscious and subconscious thoughts and actions that influence our values and shape our conduct...exploited under peace and wartime conditions. Rapid and effective reprogramming actions in response to changing operational needs are the key to high

Logistic regression applied to natural hazards: rare event logistic regression with replications

OpenAIRE

Guns, M.; Vanacker, Veerle

2012-01-01

Statistical analysis of natural hazards needs particular attention, as most of these phenomena are rare events. This study shows that the ordinary rare event logistic regression, as it is now commonly used in geomorphologic studies, does not always lead to a robust detection of controlling factors, as the results can be strongly sample-dependent. In this paper, we introduce some concepts of Monte Carlo simulations in rare event logistic regression. This technique, so-called rare event logisti...

Outsourcing Operational Logistics: Buyer Beware

National Research Council Canada - National Science Library

Woody, Lamont

2003-01-01

One of the key tasks from U.S. Secretary of Defense Donald H. Rumsfeld to his Service Chiefs is to reduce DOD's overall logistic cost and footprint while transforming the warfighter-to-logistics (tooth-to-tail) force structure...

COSTS FOR IMPLEMENTING LOGISTICS INTO THE COMPANY

OpenAIRE

Mariana Man; Maria Nowicka-Skowron

2010-01-01

The ways of approaching the logistic problems need the use of some varied techniques and means, and the elaboration of a logistic project – which would aim the entire company – mobilises multiple personnel for a period of a few months and claims the intervention of logisticians within the logistic consultancy office, whom shall also act after putting the logistic project into practice. The accomplishment of any logistic wide change within the company needs an array of activities that may be g...

Case Study on Logistics Performance

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Shahryar Sorooshian

2013-05-01

Full Text Available The paper presents research carried out at a medium‐size manufacturing organization in east Asia. The study tries to highlight the importance of supply chain management; specifically, our aim for this study is to understand logistics and performance measurement in the logistics and supply chain, and we include a theoretical discussion of online data collected and a case study of the logistic performance of a real organization. The study also examines the performance of the selected company, identifies the problems and provides recommendations for improvements. This study can be a guide for business advisers and those interested in analysing company performance, especially from a logistics viewpoint. We also suggest the methodology of this case study for those who want to have a better understanding of a business environment before starting their own business, or for benchmarking practice during strategic planning.

Comparison of multinomial logistic regression and logistic regression: which is more efficient in allocating land use?

Science.gov (United States)

Lin, Yingzhi; Deng, Xiangzheng; Li, Xing; Ma, Enjun

2014-12-01

Spatially explicit simulation of land use change is the basis for estimating the effects of land use and cover change on energy fluxes, ecology and the environment. At the pixel level, logistic regression is one of the most common approaches used in spatially explicit land use allocation models to determine the relationship between land use and its causal factors in driving land use change, and thereby to evaluate land use suitability. However, these models have a drawback in that they do not determine/allocate land use based on the direct relationship between land use change and its driving factors. Consequently, a multinomial logistic regression method was introduced to address this flaw, and thereby, judge the suitability of a type of land use in any given pixel in a case study area of the Jiangxi Province, China. A comparison of the two regression methods indicated that the proportion of correctly allocated pixels using multinomial logistic regression was 92.98%, which was 8.47% higher than that obtained using logistic regression. Paired t-test results also showed that pixels were more clearly distinguished by multinomial logistic regression than by logistic regression. In conclusion, multinomial logistic regression is a more efficient and accurate method for the spatial allocation of land use changes. The application of this method in future land use change studies may improve the accuracy of predicting the effects of land use and cover change on energy fluxes, ecology, and environment.

Conference on Logistics Management : Contributions of the Section Logistics of the German Academic Association for Business Research

CERN Document Server

Spengler, Thomas; Brinkmann, Jan; Grunewald, Martin

2016-01-01

This contributed volume contains the selected and thoroughly reviewed research papers presented at the conference on logistics management LM2015 in Braunschweig, Germany. The conference of the special interest group in logistics of the German Academic Association for Business Research (VHB) was held in conjunction with the special interest group on production of the VHB. Thus, the papers reflect the current state-of-the-art in logistics and supply chain management while focusing especially on aspects of production logistics, i.e., facility layout, inventory management, line configuration, or flexible production.

LOGISTIC ACTIVITIES IN BELARUS: TRENDS AND CHALLENGES

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P. V. Bozhanov

2017-01-01

Full Text Available Main results of investigations on logistics activities in the Republic of Belarus at year-end 2016 are presented in the paper. The paper identifies and analyzes basic components of this activity on the basis of economic evaluation of indices presented in annual State statistical reporting on logistics and transport and freight forwarding activities of the Republican organizations according to form 1-logistics (Mintrans – Ministry of Transport and Communications of the Republic of Belarus, a report of the Ministry of Transport and Communications of the Republic of Belarus on the results of the implementation of Republican Program for development of logistics systems and transit potential of the Republic of Belarus for the period of 2016–2020, World Bank reports on logistics performance index, some indices of logistics infrastructure position and also results of electronic questionnaire of the largest logistics centers of the Republic of Belarus. Methods of comparative analysis, generalization and economic analysis have been used in the process of research. The analysis has shown that a network of logistics centers with various specialization and forms of property are located and operating in all regions of the Republic of Belarus. Most of them are situated in the Minsk region near the II and IX trans-European transport corridors and in the Brest region near the border with Poland. Structure of the logistics centers includes temporary storage warehouses, customs warehouses, warehouses for general use, container terminals, car parking, customs clearance office, and automotive, railway and other cargo transport facilities. Indices of logistics activity in the Republic of Belarus demonstrate its development in 2016. Storage space of logistics centers and main financial and volumetric indices of logistics activity which are included in the State statistical reporting have been increased during in recent times. These facts testify to the demand for

Transport, logistics and the region

NARCIS (Netherlands)

Langen, de P.W.

2010-01-01

Cargo transport and logistics have a huge impact on sustainable (regional) economic development. Two broad (policy) challenges are center stage: enhancing co-location of logistics activities and improving efficiency in intermodal transport chains. Academic research can provide relevant insights for

A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.

Directory of Open Access Journals (Sweden)

Wei Zhang

Full Text Available Enterotoxigenic Escherichia coli (ETEC are important intestinal pathogens that cause diarrhea in humans and animals. Although probiotic bacteria may protect against ETEC-induced enteric infections, the underlying mechanisms are unknown. In this study, porcine intestinal epithelial J2 cells (IPEC-J2 were pre-incubated with and without Lactobacillus rhamnosus ATCC 7469 and then exposed to F4+ ETEC. Increases in TLR4 and NOD2 mRNA expression were observed at 3 h after F4+ ETEC challenge, but these increases were attenuated by L. rhamnosus treatment. Expression of TLR2 and NOD1 mRNA was up-regulated in cells pre-treated with L. rhamnosus. Pre-treatment with L. rhamnosus counteracted F4+ ETEC-induced increases in TNF-α concentration. Increased PGE2. concentrations were observed in cells infected with F4+ ETEC and in cells treated with L. rhamnosus only. A decrease in phosphorylated epidermal growth factor receptor (EGFR was observed at 3 h after F4+ ETEC challenge in cells treated with L. rhamnosus. Pre-treatment with L. rhamnosus enhanced Akt phosphorylation and increased ZO-1 and occludin protein expression. Our findings suggest that L. rhamnosus protects intestinal epithelial cells from F4+ ETEC-induced damage, partly through the anti-inflammatory response involving synergism between TLR2 and NOD1. In addition, L. rhamnosus promotes EGFR-independent Akt activation, which may activate intestinal epithelial cells in response to bacterial infection, in turn increasing tight junction integrity and thus enhancing the barrier function and restricting pathogen invasion. Pre-incubation with L. rhamnosus was superior to co-incubation in reducing the adhesion of F4+ ETEC to IPEC-J2 cells and subsequently attenuating F4+ ETEC-induced mucin layer destruction and suppressing apoptosis. Our data indicate that a selected L. rhamnosus strain interacts with porcine intestinal epithelial cells to maintain the epithelial barrier and promote intestinal epithelial

A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model.

Science.gov (United States)

Zhang, Wei; Zhu, Yao-Hong; Yang, Jin-Cai; Yang, Gui-Yan; Zhou, Dong; Wang, Jiu-Feng

2015-01-01

Enterotoxigenic Escherichia coli (ETEC) are important intestinal pathogens that cause diarrhea in humans and animals. Although probiotic bacteria may protect against ETEC-induced enteric infections, the underlying mechanisms are unknown. In this study, porcine intestinal epithelial J2 cells (IPEC-J2) were pre-incubated with and without Lactobacillus rhamnosus ATCC 7469 and then exposed to F4+ ETEC. Increases in TLR4 and NOD2 mRNA expression were observed at 3 h after F4+ ETEC challenge, but these increases were attenuated by L. rhamnosus treatment. Expression of TLR2 and NOD1 mRNA was up-regulated in cells pre-treated with L. rhamnosus. Pre-treatment with L. rhamnosus counteracted F4+ ETEC-induced increases in TNF-α concentration. Increased PGE2. concentrations were observed in cells infected with F4+ ETEC and in cells treated with L. rhamnosus only. A decrease in phosphorylated epidermal growth factor receptor (EGFR) was observed at 3 h after F4+ ETEC challenge in cells treated with L. rhamnosus. Pre-treatment with L. rhamnosus enhanced Akt phosphorylation and increased ZO-1 and occludin protein expression. Our findings suggest that L. rhamnosus protects intestinal epithelial cells from F4+ ETEC-induced damage, partly through the anti-inflammatory response involving synergism between TLR2 and NOD1. In addition, L. rhamnosus promotes EGFR-independent Akt activation, which may activate intestinal epithelial cells in response to bacterial infection, in turn increasing tight junction integrity and thus enhancing the barrier function and restricting pathogen invasion. Pre-incubation with L. rhamnosus was superior to co-incubation in reducing the adhesion of F4+ ETEC to IPEC-J2 cells and subsequently attenuating F4+ ETEC-induced mucin layer destruction and suppressing apoptosis. Our data indicate that a selected L. rhamnosus strain interacts with porcine intestinal epithelial cells to maintain the epithelial barrier and promote intestinal epithelial cell activation in

The fecal presence of enterotoxin and F4 genes as an indicator of efficacy of treatment with colistin sulfate in pigs.

Science.gov (United States)

Rhouma, Mohamed; Fairbrother, John Morris; Thériault, William; Beaudry, Francis; Bergeron, Nadia; Laurent-Lewandowski, Sylvette; Letellier, Ann

2017-01-05

Enterotoxigenic Escherichia coli (ETEC) strains producing multiple enterotoxins are important causes of post-weaning diarrhea (PWD) in pigs. The aim of the present study was to investigate the fecal presence of ETEC enterotoxin as well as F4 and F18 genes as an indicator of colistin sulfate (CS) efficacy for treatment of PWD in pigs. Forty-eight piglets were weaned at the age of 21 days, and were divided into four groups: challenged treated, challenged untreated, unchallenged treated, and unchallenged untreated. Challenge was performed using 10 9  CFU of an ETEC: F4 strain, and treatment was conducted using oral CS at the dose of 50,000 IU/kg. The fecal presence of genes encoding for STa, STb, LT, F4 and F18 was detected using PCR. The PCR amplification of ETEC virulence genes showed that nearly 100% of pigs excreted genes encoding for STa and STb toxins in the feces before the challenge. These genes, in the absence of the gene encoding F4, were considered as a marker for F4-negative ETEC. One day after ETEC: F4 oral challenge pigs in the two challenged groups excreted the genes encoding LT and F4 in the feces. These genes were considered as a marker for F4-positive ETEC. However, the gene encoding F18 was not detected in any fecal samples of the 4 groups throughout the experiment. After only 3 days of successive oral treatment with CS, a significant reduction in both the F4-positive and negative ETEC populations was observed in the challenged treated group compared to the challenged untreated group (p F4-positive and F4-negative ETEC in pigs. However, CS clinical efficiency was correlated with non-detection of F4-positive ETEC in the feces. Furthermore the fecal presence of F4-negative ETEC was not associated with clinical symptoms of post-weaning diarrhea in pigs.

OWI transportation/logistics program

International Nuclear Information System (INIS)

Shappert, L.B.; Joy, D.S.; Heiskell, M.M.; Turner, D.W.

1978-01-01

In development of a comprehensive plan to assure the availability of a transport system by 1985 capable of moving commercial radioactive wastes to federal waste repositories, a series of concerns were identified as having the potential to interfere seriously with the overall objective. These are tabulated and briefly reviewed. Activities to counteract these concerns were formulated. Logistics models were then developed. The spent fuel logistics model is described

New perspectives to the enterotoxigenic E. coli F4 porcine infection model: Susceptibility genotypes in relation to performance, diarrhoea and bacterial shedding.

Science.gov (United States)

Roubos-van den Hil, Petra J; Litjens, Ralph; Oudshoorn, Anna-Katharina; Resink, Jan Willem; Smits, Coen H M

2017-04-01

Enterotoxigenic E. coli (ETEC), causing post-weaning diarrhoea, is a major problem in weaned piglets. Individual animal responses to ETEC infection show high variability in animal experiments. Two studies were designed to optimize the ETEC F4ac infection model in piglets by combining the genotype susceptibility with performance, diarrhoea incidence and bacterial shedding. The studies were performed with respectively 120 and 80 male piglets that were tested for susceptibility or resistance towards ETEC O149:F4ac by a DNA marker based test. Three different genotypes were observed; resistant (RR), susceptible heterozygote (RS) and susceptible homozygote (SS). Piglets, were orally infected with an inoculum suspension (containing 1.5E8 CFU/ml ETEC F4ac) at day 0, 1 and 2 of the study. Performance, diarrhoea incidence and bacterial shedding were followed for 21days. In the first week after challenge a difference in average daily gain was observed between resistant and susceptible piglets in both studies. For the complete study period no significant differences were observed. Diarrhoea incidence was significantly higher in susceptible pigs compared to the resistant pigs in the first week after challenge. Bacterial shedding was much higher in the susceptible pigs and ETEC excretion lasted longer. ETEC was hardly detected in the faecal material of the resistant pigs. In conclusion, susceptible pigs showed higher diarrhoea incidence and higher numbers of faecal ETEC shedding in the first week after challenge compared to resistant pigs. The DNA marker based test can be used to select pigs that are susceptible for ETEC for inclusion in ETEC infection model, resulting in less animals needed to perform infection studies. Copyright © 2016 Elsevier B.V. All rights reserved.

Planning and management of logistic cycle

Directory of Open Access Journals (Sweden)

V. N. Kudashkin

2017-01-01

Full Text Available We are considering planning and managing of logistic cycle, its impact on the content of the main processes that comprise the cycle to implement the order for the supply of material resources for industrial consumption, as well as its practical use, effectiveness, and prospects.This research paper is made on the basis of the information, received from textbooks and scientific literature of domestic and foreign authors, as well as from other sources. The main methods, used in this work are as follows: method of system analysis, method of the theory of operations’ research, prognostics. Application of these methods allows forecasting material flows, creating the integrated management systems and controlling their movements, developing systems of logistic service, to optimize supply stock and solve a number of other tasks.A logistic approach to form a modern system of logistics will save time, reduce costs for the purchase of material resources, their delivery and storage.In modern conditions of the market economy, the considered time parameters of the logistic chain are essential for manufacturing enterprises because their records significantly increase the efficiency of the logistical system.Logistics is equipped with a special complex of economic and mathematical models, the main feature of which is the adaptability, i.e. ability to solve complex optimization problems in the operational mode and in the process of the management of material flows. The primary role of these models in a market economy is to identify quickly points of compromise.Dynamics to functional cycles gives the necessity to align resource needs «input» and «output». «Input» functional cycle is an order that specifies requirements for a product or service. Logistical system, which is able to complete fully the order of any size, as a rule, needs in the «combined» functional cycles, including different transactions and operations at different stages. The «output» of

Biopharmaceutical industry-sponsored global clinical trials in emerging countries.

Science.gov (United States)

Alvarenga, Lenio Souza; Martins, Elisabeth Nogueira

2010-01-01

To evaluate biopharmaceutical industry-sponsored clinical trials placed in countries previously described as emerging regions for clinical research, and potential differences for those placed in Brazil. Data regarding recruitment of subjects for clinical trials were retrieved from www.clinicaltrials.gov on February 2nd 2009. Proportions of sites in each country were compared among emerging countries. Multiple logistic regressions were performed to evaluate whether trial placement in Brazil could be predicted by trial location in other countries and/or by trial features. A total of 8,501 trials were then active and 1,170 (13.8%) included sites in emerging countries (i.e., Argentina, Brazil, China, Czech Republic, Hungary, India, Mexico, Poland, Russia, South Korea, and South Africa). South Korea and China presented a significantly higher proportion of sites when compared to other countries (pattractiveness for biopharmaceutical industry-sponsored clinical trials.

Digital Sound Encryption with Logistic Map and Number Theoretic Transform

Science.gov (United States)

Satria, Yudi; Gabe Rizky, P. H.; Suryadi, MT

2018-03-01

Digital sound security has limits on encrypting in Frequency Domain. Number Theoretic Transform based on field (GF 2521 – 1) improve and solve that problem. The algorithm for this sound encryption is based on combination of Chaos function and Number Theoretic Transform. The Chaos function that used in this paper is Logistic Map. The trials and the simulations are conducted by using 5 different digital sound files data tester in Wave File Extension Format and simulated at least 100 times each. The key stream resulted is random with verified by 15 NIST’s randomness test. The key space formed is very big which more than 10469. The processing speed of algorithm for encryption is slightly affected by Number Theoretic Transform.

Future electric scenarios for urban logistics

Energy Technology Data Exchange (ETDEWEB)

2012-07-01

This report is produced by the SAFE Urban Logistics project - a Norden Energy and Transport project that aims to study and analyse the prospect of integrating electric vehicles in the goods distribution of urban areas. The goal of the project is to create next practice solutions, offer promising opportunities for urban logistics operations, in order to become both more efficient and more environmentally sustainable. The SAFE Urban Logistics aims to match business models for making the application of electric vehicles within inner city logistics happen. The project will also create proposals for sustainable suitable technical solutions associated with these business models. This is one out of four reports produced by the project. Read more about the project and get access to all the reports on www.safeproject.eu. This report is the final output of the project and describes four scenarios for the future of urban logistics based on the urbanization and potential political interventions. The described scenarios will be evaluated on environmental effects and describe a potential idea that can bring this future one step closer. An array of potential business and logistics models as well as technical solutions that could be applied in order to integrate EV's on a larger basis are added at the end of the document. It is supposed to act as inspiration for the strategic development of logistics companies as well as local and governmental policies. Knowledge and experiences in this report are mainly taken from Denmark, Norway and Sweden. When it comes to logistic recommendations and experiences, influence from other parts of Europe have also been included. (Author)

Future electric scenarios for urban logistics

Energy Technology Data Exchange (ETDEWEB)

2012-07-01

This report is produced by the SAFE Urban Logistics project - a Norden Energy and Transport project that aims to study and analyse the prospect of integrating electric vehicles in the goods distribution of urban areas. The goal of the project is to create next practice solutions, offer promising opportunities for urban logistics operations, in order to become both more efficient and more environmentally sustainable. The SAFE Urban Logistics aims to match business models for making the application of electric vehicles within inner city logistics happen. The project will also create proposals for sustainable suitable technical solutions associated with these business models. This is one out of four reports produced by the project. Read more about the project and get access to all the reports on www.safeproject.eu. This report is the final output of the project and describes four scenarios for the future of urban logistics based on the urbanization and potential political interventions. The described scenarios will be evaluated on environmental effects and describe a potential idea that can bring this future one step closer. An array of potential business and logistics models as well as technical solutions that could be applied in order to integrate EV's on a larger basis are added at the end of the document. It is supposed to act as inspiration for the strategic development of logistics companies as well as local and governmental policies. Knowledge and experiences in this report are mainly taken from Denmark, Norway and Sweden. When it comes to logistic recommendations and experiences, influence from other parts of Europe have also been included. (Author)

Quality of radiotherapy reporting in randomized controlled trials of prostate cancer.

Science.gov (United States)

Soon, Yu Yang; Chen, Desiree; Tan, Teng Hwee; Tey, Jeremy

2018-06-07

Good radiotherapy reporting in clinical trials of prostate radiotherapy is important because it will allow accurate reproducibility of radiotherapy treatment and minimize treatment variations that can affect patient outcomes. The aim of our study is to assess the quality of prostate radiotherapy (RT) treatment reporting in randomized controlled trials in prostate cancer. We searched MEDLINE for randomized trials of prostate cancer, published from 1996 to 2016 and included prostate RT as one of the intervention arms. We assessed if the investigators reported the ten criteria adequately in the trial reports: RT dose prescription method; RT dose-planning procedures; organs at risk (OAR) dose constraints; target volume definition, simulation procedures; treatment verification procedures; total RT dose; fractionation schedule; conduct of quality assurance (QA) as well as presence or absence of deviations in RT treatment planning and delivery. We performed multivariate logistic regression to determine the factors that may influence the quality of reporting. We found 59 eligible trials. There was significant variability in the quality of reporting. Target volume definition, total RT dose and fractionation schedule were reported adequately in 97% of included trials. OAR constraints, simulation procedures and presence or absence of deviations in RT treatment planning and delivery were reported adequately in 30% of included trials. Twenty-four trials (40%) reported seven criteria or more adequately. Multivariable logistic analysis showed that trials that published their quality assurance results and cooperative group trials were more likely to have adequate quality in reporting in at least seven criteria. There is significant variability in the quality of reporting on prostate radiotherapy treatment in randomized trials of prostate cancer. We need to have consensus guidelines to standardize the reporting of radiotherapy treatment in randomized trials.

The recruitment of patients to trials in head and neck cancer: a qualitative study of the EaStER trial of treatments for early laryngeal cancer.

Science.gov (United States)

Hamilton, D W; de Salis, I; Donovan, J L; Birchall, M

2013-08-01

We aimed to investigate the factors contributing to poor recruitment to the EaStER trial "Early Stage glottic cancer: Endoscopic excision or Radiotherapy" feasibility study. We performed a prospective qualitative assessment of the EaStER trial at three centres to investigate barriers to recruitment and implement changes. Methods used included semi-structured interviews, focus groups and audio-recordings of recruitment encounters. First, surgeons and recruiters did not all accept the primary outcome as the rationale for the trial. Surgeons did not always adhere to the trial eligibility criteria leading to variations between centres in the numbers of "eligible" patients. Second, as both treatments were considered equally successful, recruiters and patients focused on the pragmatics of the different trial arms, favouring surgery over radiotherapy. The lack of equipoise was reflected in the way recruiters presented trial information. Third, patient views, beliefs and preferences were not fully elicited or addressed by recruiters. Fourth, in some centres, logistical issues made trial participation difficult. This qualitative research identified several major issues that explained recruitment difficulties. While there was insufficient time to address these in the EaStER trial, several factors would need to be addressed to launch further RCTs in head and neck cancer. These include the need for clear ongoing agreement among recruiting clinicians regarding details in the study protocol; an understanding of the logistical issues hindering recruitment at individual centres; and training recruiters to enable them to explain the need for randomisation and the rationale for the RCT to patients.

Logistics Sourcing Strategies in Supply Chain Design

OpenAIRE

Liu, Liwen

2007-01-01

A company's logistics sourcing strategy determines whether it structures and organizeslogistics within the company or company group or integrates logistics upstream and downstreamin the supply chain. First, three different types of logistics sourcing strategies in supply chaindesign are described and the theoretical background for the development of these strategies,including both transaction cost theory and network theory, is analyzed. Two special casesabout logistics sourcing strategy decis...

A Selected Lactobacillus rhamnosus Strain Promotes EGFR-Independent Akt Activation in an Enterotoxigenic Escherichia coli K88-Infected IPEC-J2 Cell Model

OpenAIRE

Zhang, Wei; Zhu, Yao-Hong; Yang, Jin-Cai; Yang, Gui-Yan; Zhou, Dong; Wang, Jiu-Feng

2015-01-01

Enterotoxigenic Escherichia coli (ETEC) are important intestinal pathogens that cause diarrhea in humans and animals. Although probiotic bacteria may protect against ETEC-induced enteric infections, the underlying mechanisms are unknown. In this study, porcine intestinal epithelial J2 cells (IPEC-J2) were pre-incubated with and without Lactobacillus rhamnosus ATCC 7469 and then exposed to F4+ ETEC. Increases in TLR4 and NOD2 mRNA expression were observed at 3 h after F4+ ETEC challenge, but t...

Information Logistics Research report 2

NARCIS (Netherlands)

Willems, A.; Hajdasinski, A.K.; Willems, J.

2009-01-01

The goal of this research report is to further explore the concept of Information Logistics (IL), which refers to the usage and dispatch of information and methods of logistics able to support those processes. This report is based upon 6 questions that examine IL in organizations, healthcare

Simulation Integrated Design for Logistics

NARCIS (Netherlands)

Veeke, H.P.M.

2003-01-01

The design of an innovative logistic system is a complex problem in the solution of which many disciplines are involved. Each discipline developed its own way of conceptual modeling for a logistic system based on a mono disciplinary perception. In essence this leads to a communication problem

Production-logistic system in the aspect of strategies for production planning and control and for logistic customer service

Directory of Open Access Journals (Sweden)

Łukasz Hadaś

2014-09-01

Full Text Available Background: The authors made multi-dimensional review of production and logistic strategies in order to prove their coherence in shaping internal and external supply chain. The paper is concluded with definition of production-logistic system as an object of modeling in transformation of business systems of manufacturing companies. Material and methods: The paper is based on analysis of state of the art presented in the literature on the subject of production and logistics strategies. Publications of key importance were selected to identify genesis and basic assumptions of strategies and their functioning. Comparative synthesis of logistic and production strategies identified is developed with respect to authors' experience in application of predefined tools and methods characteristic for strategies identified. Results: The result of the work conducted is consolidation of production and logistic strategies according to multi-variant customer service and original definition of production and logistic system. Conclusions: Production system and logistic system can and should be treated as equal elements in context of material flows management in internal and external supply chains. Such approach enables modeling of both systems as coherent elements realizing selected strategy of customer service.     

WP6 - Application Integration, Trials and Evaluation

DEFF Research Database (Denmark)

Prasad, Neeli R.; Cetin, Bilge Kartal; Moran, Humberto

2009-01-01

of the Total cost of ownership (TCO) associated to RFID systems as well as to confirm the ease of implementation of ASPIRE open source software (OSS) components into current IT SME infrastructure.The different pilot trials described in this deliverable are the following: • A Logistics pilot for the packing...... industry to be setup at SENSAP S.A in Greece. • A pilot for company STAFF-Jeans SA, which focuses on two distinct yet complementary scenarios, namely logistics and retail scenarios for the apparel-textiles industry • PV Lab pilot, which is demonstration pilot that aims at showcasing the ASPIRE middleware....

Leak rate analysis of the Westinghouse Reactor Coolant Pump

International Nuclear Information System (INIS)

Boardman, T.; Jeanmougin, N.; Lofaro, R.; Prevost, J.

1985-07-01

An independent analysis was performed by ETEC to determine what the seal leakage rates would be for the Westinghouse Reactor Coolant Pump (RCP) during a postulated station blackout resulting from loss of ac electric power. The object of the study was to determine leakage rates for the following conditions: Case 1: All three seals function. Case 2: No. 1 seal fails open while Nos. 2 and 3 seals function. Case 3: All three seals fail open. The ETEC analysis confirmed Westinghouse calculations on RCP seal performance for the conditions investigated. The leak rates predicted by ETEC were slightly lower than those predicted by Westinghouse for each of the three cases as summarized below. Case 1: ETEC predicted 19.6 gpm, Westinghouse predicted 21.1 gpm. Case 2: ETEC predicted 64.7 gpm, Westinghouse predicted 75.6 gpm. Case 3: ETEC predicted 422 gpm, Westinghouse predicted 480 gpm. 3 refs., 22 figs., 6 tabs

Integrated tracking of components by engineering and logistics utilizing logistics asset tracking system

Science.gov (United States)

Renfroe, Michael B.; Mcdonald, Edward J.; Bradshaw, Kimberly

1988-01-01

The Logistics Asset Tracking System (LATS) devised by NASA contains data on Space Shuttle LRUs that are daily updated to reflect such LRU status changes as repair due to failure or modification due to changing engineering requirements. The implementation of LATS has substantially increased personnel responsiveness, preventing costly delays in Space Shuttle processing and obviating hardware cannibalization. An evaluation is presented of LATS achievements in the direction of an integrated logistical support posture.

Conference Logistics Management 2013

CERN Document Server

Haasis, Hans-Dietrich; Kopfer, Herbert; Kotzab, Herbert; Schönberger, Jörn

2015-01-01

This contributed volume contains the collected research papers presented at the Logistik-Management-Konferenz 2013 organized by the VHB Wissenschaftliche Kommission Logistik, held in Bremen 2013. The papers reflect the current state-of-the-art in logistics and supply chain management, focusing on environmental sustainability in logistics and supply chain network dynamics and control. The target audience primarily comprises research experts in the field as well as practitioners but the book may also be beneficial for graduate students.

Cooperation between partners in logistics outsourcing

Directory of Open Access Journals (Sweden)

Andreja KRIŽMAN

2009-01-01

Full Text Available The purpose of this article is to present the research results from a study of impact of cooperation between logistics service providers (LSP and their customers on logistics outsourcing performance conducted in the Slovenian market. On the basis of the existing literature and some new argumentations, derived from in-depth interviews with logistics experts of providers and customers, the measurement and structural models were empirically analyzed. Existing measurement scales for the constructs of cooperation, and outsourcing performance were slightly modified for this analysis. Their purification and measurement for validity and reliability were performed. Multivariate statistical methods (EFA, CFA and SEM - Partial Least Squares were utilized and hypotheses were tested. Cooperation between partners has a significant impact on the relationship and reduces problems in logistics performance. Cooperation in the model explain 58.5% of the variance of goal achievement and 36.6% of the variance of goal exceedance logistics of outsourcing performance.

SELECTED PROBLEMS OF REVERSE LOGISTICS IN POLAND

OpenAIRE

Agata Mesjasz-Lech

2009-01-01

This paper presents the essence of reverse logistics and directions of physical and information flows between logistic network partners. It also analyses effects of implementation of the principles of reverse logistics in Poland in the years 2004-2007

Sustainable logistics. Sustainability of logistic centres by means of evaluation of emissions, protection of ressources and energy efficiency; Sustainable logistics. Nachhaltigkeit von Logistikzentren durch Emissionsbewertung, Ressourcenschonung und Energieeffizienz

Energy Technology Data Exchange (ETDEWEB)

Zadek, Hartmut; Schulz, Robert (eds.)

2011-07-01

The discussion on climate change and availability of limited resources shows that resource conservation and energy efficiency in today's targets of companies are under-represented. Cost efficiency and increase of the shareholder value with respect to a measurable success determine the daily operations. The author of the contribution under consideration considers logistics centers and supply processes for manufacturing companies. After describing basic approaches to sustainability in logistics an inventory follows based on a study of logistics service providers and manufacturing companies. Methods and tools for the evaluation of CO{sub 2} emissions and resource consumption are presented. A guideline for the development of buildings, energy audits and renewable energies is considered, identified solutions to energy-efficient logistics and modernization are given, selected best-practice examples of sustainable logistics centers are presented. The contribution ends with strategic derivation targeted at policy and state as well as companies and management.

Logistic Regression: Concept and Application

Science.gov (United States)

Cokluk, Omay

2010-01-01

The main focus of logistic regression analysis is classification of individuals in different groups. The aim of the present study is to explain basic concepts and processes of binary logistic regression analysis intended to determine the combination of independent variables which best explain the membership in certain groups called dichotomous…

Logistics Support of Naval Expeditionary Units

National Research Council Canada - National Science Library

Nilsen, Jan

2004-01-01

.... Based on literature from strategic management, logistics, and supply chain management, the research evaluates the existing theater logistics capabilities and the requirements of the supported expeditionary units...

Understanding logistic regression analysis

OpenAIRE

Sperandei, Sandro

2014-01-01

Logistic regression is used to obtain odds ratio in the presence of more than one explanatory variable. The procedure is quite similar to multiple linear regression, with the exception that the response variable is binomial. The result is the impact of each variable on the odds ratio of the observed event of interest. The main advantage is to avoid confounding effects by analyzing the association of all variables together. In this article, we explain the logistic regression procedure using ex...

District logistics analysis of the Viborg county case study

DEFF Research Database (Denmark)

Hansen, Leif Gjesing; Lise Drewes, Nielsen

The paper presents results of  the logistical flows and logistical organisation used in a district logistics analysis in Viborg county, Denmark.......The paper presents results of  the logistical flows and logistical organisation used in a district logistics analysis in Viborg county, Denmark....

WHY DO LOGISTICS AND TRANSPORT MATTER FOR DEVELOPMENT

Directory of Open Access Journals (Sweden)

Nedelescu-Ionescu Daniela

2014-07-01

Full Text Available In face of the challenges of global competition, business firms are concentrating more on the needs of customers and seeking ways to reduce costs, improve quality and meet the ever-rising expectation of their customers. To these ends, many of them have identified logistics as an area to build cost and service advantages. Logistical activities have always been vital to organizations, and therefore business logistics and supply chain management represents a synthesis of many concepts, principles, and methods from the more traditional areas of production, purchasing, transportation, economics, as well as from the disciplines of applied mathematics, and organizational behaviour. It concentrates on important activities of management such as planning, organizing, and controlling, and also on a three-way relationship of related transportation, inventory, and location strategies, which are at the heart of good logistics planning and decision making. Selecting a good logistics strategy may yield a competitive advantage. Transportation provides the flow of materials, products and persons between production facilities, warehouses, distribution centers, terminals and customer locations. The progress in techniques and management principles improves the moving load, delivery speed, service quality, operation costs, the usage of facilities and energy saving. A strong system needs a clear frame of logistics and a proper transport implements and techniques to link the producing procedures. The transportation takes a crucial part in the management of logistic. Without well-developed transportation systems, logistics could not bring its advantages into full play. A good transport system in logistics activities could provide better logistics efficiency, reduce operation cost, and promote service quality. The process determines the efficiency of moving products and energy saving. Improvements in transportation and logistics make valuable contribution to production

Logistic service providers and sustainable physical distribution

Directory of Open Access Journals (Sweden)

Stef Weijers

2012-06-01

Full Text Available Background: Logistic Service Providers main concern was to ensure reliability for a low price (Christopher, 2005. Dutch Logistic Service Providers still have these two aspects at the top of their list, but also have to take in a new aspect: sustainability. 88% Of the investigated Logistic Service Providers have included sustainability in the company's goals. These Logistic Service Providers have developed different strategies to achieve a higher level of sustainability. This paper presents the results of a study into what Logistic Service Providers say what they are doing, or intend to do, to improve sustainability for their transport services. In this way insight is given in the attitude of Dutch Logistic Service Providers towards sustainability and how they intend to translate this into business practise: internal solutions or new methods incorporating external partners. Methods: Various methods of the investigations were used, among which the analysis of the statements about the sustainabilityon the websites of various companies as well as the questionnaire per Internet. The research covered 50 largest logistics companies operating in the Netherlands and 60 companies that competed for the award "Lean and Green" advertised in the Netherlands. In addition, the Internet survey was answered by 41 companies that belong to the network of our university. Results: The investigation has shown that sustainability is handled by the logistics company as an integral part of the corporate strategy. In contrast, shippers depend in the choice of logistics services primarily on such classical aspects as the reliability or the price and the sustainability play a minor role. Conclusions: Trying to find methods to improve the sustainability, Dutch logistics service providers, in the first place, look for solutions that increase the efficiency and therefore the cost reduction potential. Solutions, which require the involvement of clients, were less often

Accumulations and development in commercial logistics

OpenAIRE

Ion Schileru

2008-01-01

The work presents a connotative periplus and an evaluation of one of the most dynamic business fields- logistics. Although used for a long time in the military department, logistics has affirmed itself relatively recent in business field, where it brought revolutionary contributions and where it has a privileged statute. There are presented particular significations of logistics from some of the application fields: production, distribution, merchandise study. In addition, the whole vision of ...

Research on 6R Military Logistics Network

Science.gov (United States)

Jie, Wan; Wen, Wang

The building of military logistics network is an important issue for the construction of new forces. This paper has thrown out a concept model of 6R military logistics network model based on JIT. Then we conceive of axis spoke y logistics centers network, flexible 6R organizational network, lean 6R military information network based grid. And then the strategy and proposal for the construction of the three sub networks of 6Rmilitary logistics network are given.

A FRAMEWORK FOR STRUCTURING CITY LOGISTICS INITIATIVES

OpenAIRE

Snežana Tadić; Slobodan Zečević

2016-01-01

Interest in the problems and conceptual solutions for city logistics is increasing each year. City is the place of largest concentration of economic and social activities, and logistics is very important for the sustainability and the economy of the city. Numerous research projects indicate that the state of urban logistics is quite critical. City logistics system is extremely complex, with a large number of participants with different roles, problems, interests and goals. They all want an at...

Urban logistics profile – Yogyakarta city, Indonesia

Directory of Open Access Journals (Sweden)

Maria Sri Asih Anna

2018-01-01

Full Text Available In recent years, more rural areas are becoming urban areas accompanied by escalation of logistics activities. Unlike passenger transport, the planning, policy and control of freight transport in developing countries have not been integrated into a reliable and efficient logistics system. Therefore, generating city logistics profile is necessary in order to support the planning of urban logistics system. This study aims to establish a logistics profile of Yogyakarta city, Indonesia, by dividing urban zones into several homogeneous groups, judging from several aspects, including city area features, product characteristics and agents/delivery profile. Logistics profile variables were calculated based on administrative boundaries, resulting in 45 areas to be investigated. Profiles were matched in groups of homogeneous stores (A, large commercial stores (C and residential areas with local trade (D,with one overlapping profile, i.e. profile A and profile D, in some locations in the middle of the city.

An Exploratory Analysis of Reverse Logistics in Flanders

NARCIS (Netherlands)

Verstrepen, Sven; Cruijssen, Frans; Brito, Marisa P De; Dullaert, Wout

2007-01-01

This paper reports on a reverse logistics survey of shippers and logistics service providers in Flanders, one of the leading logistics regions in Europe. We characterise the reverse logistics activities with respect to return reasons, recovery options, outsourcing, lifecycle length and value of

Decision support modeling for sustainable food logistics management

NARCIS (Netherlands)

Soysal, M.

2015-01-01

Summary

For the last two decades, food logistics systems have seen the transition from traditional Logistics Management (LM) to Food Logistics Management (FLM), and successively, to Sustainable Food Logistics Management (SFLM). Accordingly, food industry has been subject to the recent

OUTBOUND LOGISTICS MANAGEMENT IN MANUFACTURING COMPANIES IN GHANA

OpenAIRE

Kwame Owusu Kwateng; John Frimpong Manso; Richard Osei-Mensah

2014-01-01

The optimization of outbound logistics operations through consolidation and collaboration using a third party logistics provider has potential to contribute to the profitability of an organization by lowering the cost of warehousing and transportation. The purpose of this paper is to assess outbound logistics of a manufacturing company (Guinness Ghana Breweries Limited) using the services of a third party logistics provider (DHL). Empirical research was employed to explore outbound logistics ...

Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets

NARCIS (Netherlands)

Geus, de B.; Harmsen, M.; Zijderveld, van F.

1998-01-01

In the present study we describe the effect of oral application of mAB specific for ETEC F4(ac) fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4(ac) epitopes protect animals against ETEC specific pathology. Moreover,

Design for logistics to gain competitive advantage

DEFF Research Database (Denmark)

Chaudhuri, Atanu; Biskoptsø, Rogvi

2015-01-01

. Considering logistical requirements in design of a product which is heavy and bulky and involves significant logistics costs enabled to firm to gain competitiveness. The exercise underscored the importance of understanding logistical requirements, freight costs and dimensional constraints early in the design...... phase which is usually neglected by start-up firms focused on the engineering driven innovativeness of the products. The processes developed along with guidelines facilitate future use which can help such firms to proactively consider logistics requirements at the design stage....

Rise of humanitarian logistics

CSIR Research Space (South Africa)

Maspero, EL

2008-07-01

Full Text Available but was described as fairly routine for a company of Walmart’s size with 117 distribution centres spread around the country. The nonchalant response by Rollin Ford, (Walmart’s executive vice president of logistics and supply chain) says it all, “that’s what we do...%20and%20challenges%22 [3] Boorstin, J. 2005. New lessons to learn. Fortune. 3 October. [4] Davidson, A.L. 2006. Key Performance Indicators in Humanitarian Logistics. MLOG Thesis, 2006. Viewed 24 October 2006. [5] http...

Torrefaction Quality Control. Based on logistic and end-user requirements

Energy Technology Data Exchange (ETDEWEB)

Zwart, R.W.R.; Kiel, J.H.A.; Verhoeff, F.; Pels, J.R. [ECN Biomass and Energy Efficiency, Petten (Netherlands)

2011-10-15

Torrefaction is a promising key technology for boosting large-scale implementation of bioenergy. It involves the heating of biomass in the absence of oxygen to a temperature of 200 to 300C. As a result, the biomass becomes easy to grind and water resistant, which reduces risks of spontaneous biological degradation and heating and permits outdoor storage. By combining torrefaction with pelletisation or briquetting, biomass is converted into a high-energy-density commodity solid fuel with superior properties in view of (long-distance) transport, handling and storage, and also in many major end-use applications (e.g., co-firing in coal-fired power stations, gasification-based biofuels production and production of bio-based chemicals). ECN is executing an extensive research and development program in which the most important aspects of torrefaction and pelletisation upstream as well as logistics and end-use downstream are investigated. ECN's torrefaction technology is now proven on bench-, lab- and pilot scale, with the 50-100 kg/hr pilot scale plant producing tonnes of torrefied material already used in specific semi-industrial milling and pelletisation trials. Furthermore, quality analysis are being performed in relation to logistics, on-site transport and handling, and end-use application of the torrefied wood pellets (i.e. co-firing in existing combustion and gasification plants). In the presentation, the results of torrefaction tests with different types of biomass (deciduous, herbaceous and coniferous) are outlined, including the consequences for logistics and end-use application. Furthermore, an update is be provided on the scale-up and demonstration of the ECN torrefaction technology, for which ECN has teamed up with a leading European energy company as well as a worldwide operating technology supplier to continue to develop its torrefaction technology and bring it to the market.

Reverse logistics in the construction industry.

Science.gov (United States)

Hosseini, M Reza; Rameezdeen, Raufdeen; Chileshe, Nicholas; Lehmann, Steffen

2015-06-01

Reverse logistics in construction refers to the movement of products and materials from salvaged buildings to a new construction site. While there is a plethora of studies looking at various aspects of the reverse logistics chain, there is no systematic review of literature on this important subject as applied to the construction industry. Therefore, the objective of this study is to integrate the fragmented body of knowledge on reverse logistics in construction, with the aim of promoting the concept among industry stakeholders and the wider construction community. Through a qualitative meta-analysis, the study synthesises the findings of previous studies and presents some actions needed by industry stakeholders to promote this concept within the real-life context. First, the trend of research and terminology related with reverse logistics is introduced. Second, it unearths the main advantages and barriers of reverse logistics in construction while providing some suggestions to harness the advantages and mitigate these barriers. Finally, it provides a future research direction based on the review. © The Author(s) 2015.

5th International Conference on Dynamics in Logistics

CERN Document Server

Kotzab, Herbert; Pannek, Jürgen

2017-01-01

These proceedings contain research papers presented at the 5th International Conference on Dynamics in Logistics, held in Bremen, Germany, February 2016. The conference is concerned with dynamic aspects of logistic processes and networks. The spectrum of topics reaches from modeling, planning and control of processes over supply chain management and maritime logistics to innovative technologies and robotic applications for cyber-physical production and logistic systems. The growing dynamic confronts the area of logistics with completely new challenges: it must become possible to describe, identify and analyze the process changes. Moreover, logistic processes and networks must be redevised to be rapidly and flexibly adaptable to continuously changing conditions. The book primarily addresses researchers and practitioners from the field of industrial engineering and logistics, but it may also be beneficial for graduate students.

Satellite rainfall retrieval by logistic regression

Science.gov (United States)

Chiu, Long S.

1986-01-01

The potential use of logistic regression in rainfall estimation from satellite measurements is investigated. Satellite measurements provide covariate information in terms of radiances from different remote sensors.The logistic regression technique can effectively accommodate many covariates and test their significance in the estimation. The outcome from the logistical model is the probability that the rainrate of a satellite pixel is above a certain threshold. By varying the thresholds, a rainrate histogram can be obtained, from which the mean and the variant can be estimated. A logistical model is developed and applied to rainfall data collected during GATE, using as covariates the fractional rain area and a radiance measurement which is deduced from a microwave temperature-rainrate relation. It is demonstrated that the fractional rain area is an important covariate in the model, consistent with the use of the so-called Area Time Integral in estimating total rain volume in other studies. To calibrate the logistical model, simulated rain fields generated by rainfield models with prescribed parameters are needed. A stringent test of the logistical model is its ability to recover the prescribed parameters of simulated rain fields. A rain field simulation model which preserves the fractional rain area and lognormality of rainrates as found in GATE is developed. A stochastic regression model of branching and immigration whose solutions are lognormally distributed in some asymptotic limits has also been developed.

Analysis of Jingdong Mall Logistics Distribution Model

Science.gov (United States)

Shao, Kang; Cheng, Feng

In recent years, the development of electronic commerce in our country to speed up the pace. The role of logistics has been highlighted, more and more electronic commerce enterprise are beginning to realize the importance of logistics in the success or failure of the enterprise. In this paper, the author take Jingdong Mall for example, performing a SWOT analysis of their current situation of self-built logistics system, find out the problems existing in the current Jingdong Mall logistics distribution and give appropriate recommendations.

Research on logistics scheduling based on PSO

Science.gov (United States)

Bao, Huifang; Zhou, Linli; Liu, Lei

2017-08-01

With the rapid development of e-commerce based on the network, the logistics distribution support of e-commerce is becoming more and more obvious. The optimization of vehicle distribution routing can improve the economic benefit and realize the scientific of logistics [1]. Therefore, the study of logistics distribution vehicle routing optimization problem is not only of great theoretical significance, but also of considerable value of value. Particle swarm optimization algorithm is a kind of evolutionary algorithm, which is based on the random solution and the optimal solution by iteration, and the quality of the solution is evaluated through fitness. In order to obtain a more ideal logistics scheduling scheme, this paper proposes a logistics model based on particle swarm optimization algorithm.

Logistics performance measurement system for the automotive industry

OpenAIRE

Dörnhöfer, Martin;Schröder, Falk;Günthner, Willibald A.

2017-01-01

Logistics can be seen as a key competitive factor in the automotive industry due to the rising number of model variants and options. With the increasing importance of logistics (Gunasekaran et al. in Int J Prod Econ 87(3):333-347, 2004), the evaluation of logistics effectiveness and efficiency is gaining increased attention. Logistics performance management (PM) is the key to quantifying the current state and improvement potentials within logistics. To account for the increasing importance of...

The Effect of Logistic Controlling on Business Processes

OpenAIRE

Szilvia, Berek Méhesné

2014-01-01

The increase in the significance of logistics can be attributed to two major reasons: the increasing cost sensitivity of companies and the necessity for the higher fulfilment of customer needs. Logistic controlling is a tool of management used to coordinate logistic activities and to reach logistic managerial decisions by providing information through the analysis of the system. The up-to-date and precise information that can be gained from the logistic controlling system helps the management...

Neo-logistic model for the growth of bacteria

OpenAIRE

Tashiro, Tohru; Yoshimura, Fujiko

2017-01-01

We propose a neo-logistic model that can describe bacterial growth data precisely. This model is not derived by modifying the logistic model formally, but by incorporating the synthesis of inducible enzymes into the logistic model indirectly. Therefore, the meaning of the parameters of the neo-logistic model becomes physically clear. The neo-logistic model can approximate bacterial growth better than models previously presented, and predict the order of the saturated number of bacteria in the...

A sustainable urban logistics dashboard from the perspective of a group of logistics managers

OpenAIRE

Morana , Joëlle; Gonzalez-Feliu , Jesus

2014-01-01

Urban logistics has now become a priority issue in both supply chain management and urban planning. However, the different stakeholders involved develop different approaches whose aims and objectives do not always coincide and sometimes present conflicting standpoints. The aim of this paper is to complete existing literature by proposing a sustainable dashboard for evaluating the sustainable performance of urban delivery systems, from the perspective of operational logistics managers, one of ...

Strategies on the Implementation of China's Logistics Information Network

Science.gov (United States)

Dong, Yahui; Li, Wei; Guo, Xuwen

The economic globalization and trend of e-commerce network have determined that the logistics industry will be rapidly developed in the 21st century. In order to achieve the optimal allocation of resources, a worldwide rapid and sound customer service system should be established. The establishment of a corresponding modern logistics system is the inevitable choice of this requirement. It is also the inevitable choice for the development of modern logistics industry in China. The perfect combination of modern logistics and information network can better promote the development of the logistics industry. Through the analysis of Status of Logistics Industry in China, this paper summed up the domestic logistics enterprise logistics information system in the building of some common problems. According to logistics information systems planning methods and principles set out logistics information system to optimize the management model.

Logistic Vehicle System Replacement Cost Estimate

National Research Council Canada - National Science Library

Stinson, Margaret

1998-01-01

The Logistics Vehicle System (LVS) was originally fielded from 1985-1989. Most of the LVS fleet will reach end-of-service life in 2005, therefore the goal of the Logistics Vehicle System Replacement (LVSR...

Multicriteria Optimisation in Logistics Forwarder Activities

Directory of Open Access Journals (Sweden)

Tanja Poletan Jugović

2007-05-01

Full Text Available Logistics forwarder, as organizer and planner of coordinationand integration of all the transport and logistics chains elements,uses adequate ways and methods in the process of planningand decision-making. One of these methods, analysed inthis paper, which could be used in optimisation of transportand logistics processes and activities of logistics forwarder, isthe multicriteria optimisation method. Using that method, inthis paper is suggested model of multicriteria optimisation of logisticsforwarder activities. The suggested model of optimisationis justified in keeping with method principles of multicriteriaoptimization, which is included in operation researchmethods and it represents the process of multicriteria optimizationof variants. Among many different processes of multicriteriaoptimization, PROMETHEE (Preference Ranking OrganizationMethod for Enrichment Evaluations and Promcalc& Gaia V. 3.2., computer program of multicriteria programming,which is based on the mentioned process, were used.

Regional Logistics Information Resources Integration Patterns and Countermeasures

Science.gov (United States)

Wu, Hui; Shangguan, Xu-ming

Effective integration of regional logistics information resources can provide collaborative services in information flow, business flow and logistics for regional logistics enterprises, which also can reduce operating costs and improve market responsiveness. First, this paper analyzes the realistic significance on the integration of regional logistics information. Second, this paper brings forward three feasible patterns on the integration of regional logistics information resources, These three models have their own strengths and the scope of application and implementation, which model is selected will depend on the specific business and the regional distribution of enterprises. Last, this paper discusses the related countermeasures on the integration of regional logistics information resources, because the integration of regional logistics information is a systems engineering, when the integration is advancing, the countermeasures should pay close attention to the current needs and long-term development of regional enterprises.

Multi-donor trust fund for sustainable logistics (MDTF-SL) : position note on green logistics (supply chains)

NARCIS (Netherlands)

Fransoo, J.C.

2014-01-01

Logistics – the services, knowledge, and infrastructure that allow for the free movement of goods and people – is now recognized as a key driver of competitiveness and economic development. Efficient logistics systems are a precondition for regions, countries, cities, and businesses to participate

ISS Logistics Hardware Disposition and Metrics Validation

Science.gov (United States)

Rogers, Toneka R.

2010-01-01

I was assigned to the Logistics Division of the International Space Station (ISS)/Spacecraft Processing Directorate. The Division consists of eight NASA engineers and specialists that oversee the logistics portion of the Checkout, Assembly, and Payload Processing Services (CAPPS) contract. Boeing, their sub-contractors and the Boeing Prime contract out of Johnson Space Center, provide the Integrated Logistics Support for the ISS activities at Kennedy Space Center. Essentially they ensure that spares are available to support flight hardware processing and the associated ground support equipment (GSE). Boeing maintains a Depot for electrical, mechanical and structural modifications and/or repair capability as required. My assigned task was to learn project management techniques utilized by NASA and its' contractors to provide an efficient and effective logistics support infrastructure to the ISS program. Within the Space Station Processing Facility (SSPF) I was exposed to Logistics support components, such as, the NASA Spacecraft Services Depot (NSSD) capabilities, Mission Processing tools, techniques and Warehouse support issues, required for integrating Space Station elements at the Kennedy Space Center. I also supported the identification of near-term ISS Hardware and Ground Support Equipment (GSE) candidates for excessing/disposition prior to October 2010; and the validation of several Logistics Metrics used by the contractor to measure logistics support effectiveness.

Complete Genome Sequence of Enterotoxigenic Escherichia coli Siphophage Seurat.

Science.gov (United States)

Doan, Dung P; Lessor, Lauren E; Hernandez, Adriana C; Kuty Everett, Gabriel F

2015-02-26

Enterotoxigenic Escherichia coli (ETEC) is one of the leading causes of diarrhea in developing countries. Bacteriophage therapy has the potential to aid in the prevention and treatment of ETEC-related illness. To that end, we present here the complete genome of ETEC siphophage Seurat and describe its major features. Copyright © 2015 Doan et al.

Focused Logistics: Time for Functional Command

National Research Council Canada - National Science Library

Mintzlaff, Jeffrey G

2005-01-01

.... Unfortunately, logistical support is often taken for granted. As a result, the U.S. Military's logistical system has become sluggish, often unreliable, and expensive, in part due to its fragmented and inefficient organizational structure. The U.S...

Co-location synergies : specialized versus diverse logistics concentration areas

OpenAIRE

Heuvel, van den, F.P.; Langen, de, P.W.; Donselaar, van, K.H.; Fransoo, J.C.

2012-01-01

Purpose: The purpose of this paper is to contribute to the understanding of spatial concentration of logistics firms by empirically analyzing synergies through co-location and investigating whether co-location of logistics establishments in specialized logistics concentration areas results in benefits compared to co-location in diverse logistics concentration areas. Methodology: A survey among managers of 128 logistics establishments located in logistics concentration areas was used to test f...

Production Logistics Simulation Supported by Process Description Languages

Directory of Open Access Journals (Sweden)

Bohács Gábor

2016-03-01

Full Text Available The process description languages are used in the business may be useful in the optimization of logistics processes too. The process description languages would be the obvious solution for process control, to handle the main sources of faults and to give a correct list of what to do during the logistics process. Related to this, firstly, the paper presents the main features of the frequent process description languages. The following section describes the currently most used process modelling languages, in the areas of production and construction logistics. In addition, the paper gives some examples of logistics simulation, as another very important field of logistics system modelling. The main edification of the paper, the logistics simulation supported by process description languages. The paper gives a comparison of a Petri net formal representation and a Simul8 model, through a construction logistics model, as the major contribution of the research.

DECISION-MAKING STRATEGIES REGARDING LOGISTICS ORGANIZATION

Directory of Open Access Journals (Sweden)

Ioana Olariu

2014-07-01

Full Text Available In the face of higher costs of operation and increasing pressures from customers for better service, the logistics organization must adapt to meet the challenge. An understanding of the factors that make organizations effective, and a knowledge of how these factors interrelate, are the first steps towards developing the system for a firm’s customers. Logistics organizations must of necessity become more cost and service efficient. An understanding of the factors that affect a firm’s organizational effectiveness, along with strategies to reveal weaknesses or deficiencies, can help create more efficient logistics systems. Organizational changes form the basis for procedural modifications that can reduce costs or improve service. Many firms have shown significant improvements in their logistics cost-service mix as a result of organizational changes. Logistics organizations are generally structured along the following lines: strategic versus operational, centralized versus decentralized and line versus staff, in various combinations. There is no single ideal organizational structure, but there are important elements that comprise an effective organization. In general, the factors contributing to organizational effectiveness can be categorized as organizational characteristics, environmental characteristics, employee characteristics, and managerial policies and practices.

Analysis of Unmanned Systems in Military Logistics

Science.gov (United States)

2016-12-01

performance measures: customer satisfaction , flexibility, visibility, and trust. If we apply this explanation of Li and Schulze (2011) to the military...unmanned systems, initially, we aimed to define current and proposed unmanned applications in civilian-sector logistics and current military...aimed to define current and proposed unmanned applications in civilian-sector logistics and current military logistics challenges. Then, justifying

Competitive Internal Logistics Systems through Automation

OpenAIRE

Granlund, Anna

2011-01-01

The growing demand for products and services puts great pressure on logistics performance and enhances the role that logistics plays in determining a company’s competitiveness. This research focuses on internal logistics systems, which includes all logistics activities and processes within the physical limits of an isolated company. Internal logistics is vital for the overall function of many companies. However, despite its importance, this part of logistics has traditionally not been viewed ...

The Role of Reverse Logistics on the European Market

OpenAIRE

Irina Tobosaru; Irina Nicolau

2009-01-01

The Council of Logistics Management has published the first definition of reverse logistics in 1992: “The term reverse logistics refers to the role of logistics in recycling waste, in the distribution and the handling of dangerous materials. A broader definition includes in the reverse logistics, activities that have the purpose of reducing the resources, of recycling, replacing, reusing the materials and relocating them”. Reverse logistics can be also defined using as standard the definition...

LOGISTICS MANAGEMENT IN THE GENERAL STRUCTURE OF COMPANY MANAGEMENT

OpenAIRE

SERGIU PETROVICI; ALA GUDIMA

2011-01-01

The paper is dedicated to the place of logistics management in the general structure of an enterprise. It states some rules to improve the logistic system through development of logistic management as integral system and through a complex approach, development of a market-orientated logistic management with clear short-term and long-term purposes, development of information system in logistics. The course of Logistics Management is taught at the Cooperative-Commercial University of Moldova at...

LOGISTICS AS A PART OF INNOVATION PROCESS

Directory of Open Access Journals (Sweden)

Erika Loučanová

2016-03-01

Full Text Available The paper deals with the importance of logistics in innovation process. The issue is focused on management of different logistic processes building on the innovation and on innovation process. However, logistics is an essential part of this process. The results describe logistics chain within innovation process for the satisfaction of customers´ demand and fulfilment of customers’ requests on the innovation. This approach involves “7S of logistics” which means: “create proper innovation, in the proper quality, for the right place and in the right time, as well as, with the proper price and package”.

Generation of fractals from complex logistic map

International Nuclear Information System (INIS)

Rani, Mamta; Agarwal, Rashi

2009-01-01

Remarkably benign looking logistic transformations x n+1 = r x n (1 - x n ) for choosing x 0 between 0 and 1 and 0 < r ≤ 4 have found a celebrated place in chaos, fractals and discrete dynamics. The strong physical meaning of Mandelbrot and Julia sets is broadly accepted and nicely connected by Christian Beck [Beck C. Physical meaning for Mandelbrot and Julia sets. Physica D 1999;125(3-4):171-182. Zbl0988.37060] to the complex logistic maps, in the former case, and to the inverse complex logistic map, in the latter case. The purpose of this paper is to study the bounded behavior of the complex logistic map using superior iterates and generate fractals from the same. The analysis in this paper shows that many beautiful properties of the logistic map are extendable for a larger value of r.

Logistics of LEP installation

International Nuclear Information System (INIS)

Genier, C.; Capper, S.

1988-01-01

The size of the LEP project, coupled with the tight construction schedules, calls for organized planning, logistics, monitoring and control. This is being carried out at present using tools such as ORACLE the Relational Database Management System, running on a VAX cluster for data storage and transfer, micro-computers for on-site follow-up, and PC's running Professional ORACLE, DOS and XENIX linked to a communications network to receive data feedback concerning transport and handling means. Following over 2 years of installations, this paper presents the methods used for the logistics of installation and their results

Logistics Reduction and Repurposing Beyond Low Earth Orbit

Science.gov (United States)

Ewert, Michael K.; Broyan, James L., Jr.

2012-01-01

All human space missions, regardless of destination, require significant logistical mass and volume that is strongly proportional to mission duration. Anything that can be done to reduce initial mass and volume of supplies or reuse items that have been launched will be very valuable. Often, the logistical items require disposal and represent a trash burden. Logistics contributions to total mission architecture mass can be minimized by considering potential reuse using systems engineering analysis. In NASA's Advanced Exploration Systems "Logistics Reduction and Repurposing Project," various tasks will reduce the intrinsic mass of logistical packaging, enable reuse and repurposing of logistical packaging and carriers for other habitation, life support, crew health, and propulsion functions, and reduce or eliminate the nuisance aspects of trash at the same time. Repurposing reduces the trash burden and eliminates the need for hardware whose function can be provided by use of spent logistical items. However, these reuse functions need to be identified and built into future logical systems to enable them to effectively have a secondary function. These technologies and innovations will help future logistics systems to support multiple exploration missions much more efficiently.

Roadmap towards a smart logistics ecosystem

NARCIS (Netherlands)

Hofman, W.J.; Bastiaansen, H.J.M.

2014-01-01

Currently, the fundamentals of a technical infrastructure for a logistics ‘systems-of-systems’ are laid, facilitating improved, more effective and efficient logistics services based on higher levels of self-organization. Through situation awareness with enhanced methods for sharing (real-time) data,

Production-logistic system in the aspect of strategies for production planning and control and for logistic customer service

OpenAIRE

Łukasz Hadaś; Agnieszka Stachowiak; Piotr Cyplik

2014-01-01

Background: The authors made multi-dimensional review of production and logistic strategies in order to prove their coherence in shaping internal and external supply chain. The paper is concluded with definition of production-logistic system as an object of modeling in transformation of business systems of manufacturing companies. Material and methods: The paper is based on analysis of state of the art presented in the literature on the subject of production and logistics strategies. Publ...

The system for statistical analysis of logistic information

Directory of Open Access Journals (Sweden)

Khayrullin Rustam Zinnatullovich

2015-05-01

Full Text Available The current problem for managers in logistic and trading companies is the task of improving the operational business performance and developing the logistics support of sales. The development of logistics sales supposes development and implementation of a set of works for the development of the existing warehouse facilities, including both a detailed description of the work performed, and the timing of their implementation. Logistics engineering of warehouse complex includes such tasks as: determining the number and the types of technological zones, calculation of the required number of loading-unloading places, development of storage structures, development and pre-sales preparation zones, development of specifications of storage types, selection of loading-unloading equipment, detailed planning of warehouse logistics system, creation of architectural-planning decisions, selection of information-processing equipment, etc. The currently used ERP and WMS systems did not allow us to solve the full list of logistics engineering problems. In this regard, the development of specialized software products, taking into account the specifics of warehouse logistics, and subsequent integration of these software with ERP and WMS systems seems to be a current task. In this paper we suggest a system of statistical analysis of logistics information, designed to meet the challenges of logistics engineering and planning. The system is based on the methods of statistical data processing.The proposed specialized software is designed to improve the efficiency of the operating business and the development of logistics support of sales. The system is based on the methods of statistical data processing, the methods of assessment and prediction of logistics performance, the methods for the determination and calculation of the data required for registration, storage and processing of metal products, as well as the methods for planning the reconstruction and development

The influence of logistics potentials on business management

Directory of Open Access Journals (Sweden)

Rafał Matwiejczuk

2012-09-01

Full Text Available Background: Logistics is more and more often perceived as an integrated potential of changes in a business management system. Among the particular potentials, the key importance is assigned to logistics resources, capabilities, and particularly competences. Methods: The article points at exploitation of possibilities of logistics potentials in achieving desired changes in business management and reaching desired market and economic effects by a company. Except for literature studies, empirical research has been conducted in 111 companies operating in Poland.  Results and conclusions:  Research results have shown several symptoms of logistics influence on business management system. The significance of logistics potentials in business management system capacity development has been partially confirmed. Due to logistics potentials, the company can be more effective and efficient in reaching expected market and economic outcomes.  

Generation of fractals from complex logistic map

Energy Technology Data Exchange (ETDEWEB)

Rani, Mamta [Galgotias College of Engg. and Technology, Greater Noida (India)], E-mail: mamtarsingh@rediffmail.com; Agarwal, Rashi [IEC College of Engg. and Tech., Greater Noida (India)], E-mail: agarwal_rashi@yahoo.com

2009-10-15

Remarkably benign looking logistic transformations x{sub n+1} = r x{sub n}(1 - x{sub n}) for choosing x{sub 0} between 0 and 1 and 0 < r {<=} 4 have found a celebrated place in chaos, fractals and discrete dynamics. The strong physical meaning of Mandelbrot and Julia sets is broadly accepted and nicely connected by Christian Beck [Beck C. Physical meaning for Mandelbrot and Julia sets. Physica D 1999;125(3-4):171-182. Zbl0988.37060] to the complex logistic maps, in the former case, and to the inverse complex logistic map, in the latter case. The purpose of this paper is to study the bounded behavior of the complex logistic map using superior iterates and generate fractals from the same. The analysis in this paper shows that many beautiful properties of the logistic map are extendable for a larger value of r.

Technological Innovation for China’s Logistics Industry

Directory of Open Access Journals (Sweden)

Chieh-Yu Lin

2008-01-01

Full Text Available China’s logistics industry has started to pay attention to adopt more efficient logistics technologies to provide better services for their customers. This paper employes the questionnaire survey to study the factors influencing the adoption of technological innovations by logistics service providers in China as well as the influences of technological innovation on supply chain performance. Technological innovations are categorized into data acquisition technologies, information technologies, warehousing technologies, and transportation technologies. The results show that the adoption of technological innovations is significantly influenced by technological, organizational and environmental factors, and adopting innovative technologies will increase supply chain performance for the logistics industry in China.

Consumer Perception on Halal meat logistics

NARCIS (Netherlands)

Tieman, H.; Ghazali, M.C.; Vorst, van der J.G.A.J.

2013-01-01

Purpose – The purpose of this paper is to investigate the preferred minimum level of segregation for halal meat in supermarket, transport, storage and terminals; the responsibility of halal logistics; and the willingness to pay for halal logistics in a Muslim and non-Muslim country.

Smart logistics: an enterprise architecture perspective

NARCIS (Netherlands)

van Sinderen, Marten J.; Singh, Prince Mayurank; Wieringa, Roel J.

Logistic enterprises are increasingly becoming smarter and more ecient by using real-time contextual data. A currently unsolved problem for small to medium sized logistic service providers (SMLSPs) is, how to use real time data in existing business processes & IT systems. Enterprise architecture can

Methodical approach to financial stimulation of logistics managers

OpenAIRE

Melnykova Kateryna V.

2014-01-01

The article offers a methodical approach to financial stimulation of logistics managers, which allows calculation of the incentive amount with consideration of profit obtained from introduction of optimisation logistics solutions. The author generalises measures, which would allow increase of stimulation of labour of logistics managers by the enterprise top managers. The article marks out motivation factors, which exert influence upon relation of logistics managers to execution of optimisatio...

Managing logistical processes in franchise retail trade networks

OpenAIRE

Grigorenko Tatyana N.; Kochubey Dmitriy V.

2013-01-01

The article analyses approaches to organisation of internal logistics of franchise trade networks and methodical provision of assessment of results of logistical activity at companies of franchise networks. The article justifies urgency of application of referent models of management of supply chains in construction of a system of management of logistical activity of franchise networks. It offers classification of models of management of internal logistics of franchise retail trade networks. ...

CONCEPTUAL ISSUES REGARDING REVERSE LOGISTICS

Directory of Open Access Journals (Sweden)

Ioana Olariu

2013-12-01

Full Text Available As the power of consumers is growing, the product return for customer service and customer retention has become a common practice in the competitive market, which propels the recent practice of reverse logistics in companies. Many firms attracted by the value available in the flow, have proactively participated in handling returned products at the end of their usefulness or from other parts of the product life cycle. Reverse logistics is the flow and management of products, packaging, components and information from the point of consumption to the point of origin. It is a collection of practices similar to those of supply chain management, but in the opposite direction, from downstream to upstream. It involves activities such as reuse, repair, remanufacture, refurbish, reclaim and recycle. For the conventional forward logistics systems, the flow starts upstream as raw materials, later as manufactured parts and components to be assembled and continues downstream to reach customers as final products to be disposed once they reach their economic or useful lives. In reverse logistics, the disposed products are pushed upstream to be repaired, remanufactured, refurbished, and disassembled into components to be reused or as raw material to be recycled for later use.

Logistics innovation development

DEFF Research Database (Denmark)

Pedrosa, Alex; Blazevic, Vera; Jasmand, Claudia

2015-01-01

Purpose – The purpose of this paper is to investigate the microfoundations of customer knowledge acquisition during logistics innovation development. Specifically, the authors explore the activities and behaviors of employees with customer contact (i.e. boundary-spanning employees (BSEs)) to deepen...

Logistics Takes Command

NARCIS (Netherlands)

Marullo, F.

2015-01-01

The term "logistics" derives from the Greek logizomai standing for the art of reckoning, organising, planning. Through time it achieved a strict military connotation, dealing with the composition, lodging and movements of troops, the arrangement of provisions in hostile territories, the

Logistic innovations in transport

Directory of Open Access Journals (Sweden)

Mirosław Antonowicz

2014-03-01

Full Text Available Introduction: The article discusses the issue of logistic innovations in transport. The essentials of logistic innovations in transport together with some examples of specific innovations are presented. The role of the client's needs in transport innovations is indicated. The most vital postulates affecting the innovativeness of shipping companies and derived from the author's experience as well as scholarly publications, are time, safety, reliability as well as comprehensiveness of service offer. Following the analysis of the issue, and on the grounds of Kaizen's and Lean's method, the concept of continuous innovations is suggested as very useful for the development of transport. The potential of clusters as the source of logistic innovations in transport is emphasised. Methods: The discussion of the issue was preceded by the author's analysis of written sources on innovativeness, the evaluation of ratings of innovativeness as well as the analysis of rewarded innovative solutions in transport subsequent to the businesses participation in the programme of innovative solutions in transport. The role of innovation practical business operations is argued following the analysis of some strategic documents such as: 2011 White Paper and the Strategy for the Development of Transport by 2020 adopted by the Polish government in 2013. Aim: The aim of the article is to present the role and significance of the issue of logistic innovations in transport and to cite instances of practical solutions implemented by shipping companies, the solutions which resulted in measurable effects. Following the author's observation of the instances of innovative solutions as well as his analysis of the ratings of innovativeness, the article aims to present the conclusions as for the specific kinds of activities which are indispensable to foster innovativeness in transport. Conclusions: The conclusions derived from the author's analyses and observations show that logistic

Exploration Mission Benefits From Logistics Reduction Technologies

Science.gov (United States)

Broyan, James Lee, Jr.; Schlesinger, Thilini; Ewert, Michael K.

2016-01-01

Technologies that reduce logistical mass, volume, and the crew time dedicated to logistics management become more important as exploration missions extend further from the Earth. Even modest reductions in logical mass can have a significant impact because it also reduces the packing burden. NASA's Advanced Exploration Systems' Logistics Reduction Project is developing technologies that can directly reduce the mass and volume of crew clothing and metabolic waste collection. Also, cargo bags have been developed that can be reconfigured for crew outfitting and trash processing technologies to increase habitable volume and improve protection against solar storm events are under development. Additionally, Mars class missions are sufficiently distant that even logistics management without resupply can be problematic due to the communication time delay with Earth. Although exploration vehicles are launched with all consumables and logistics in a defined configuration, the configuration continually changes as the mission progresses. Traditionally significant ground and crew time has been required to understand the evolving configuration and locate misplaced items. For key mission events and unplanned contingencies, the crew will not be able to rely on the ground for logistics localization assistance. NASA has been developing a radio frequency identification autonomous logistics management system to reduce crew time for general inventory and enable greater crew self-response to unplanned events when a wide range of items may need to be located in a very short time period. This paper provides a status of the technologies being developed and there mission benefits for exploration missions.

Logistics & Fintech : from direct benefits to big impacts

NARCIS (Netherlands)

2017-01-01

This whitepaper is the result of the Logistics & Fintech programme, focusing on exchanging knowledge, promoting interest and creating collaboration opportunities between the fintech and logistics industries. This whitepaper presents our vision of financial innovation for the logistics industry,

Big data interoperability challenges for logistics

NARCIS (Netherlands)

Singh, Prince Mayurank; van Sinderen, Marten J.; Zelm, Martin; Doumeingts, Guy; Mendonca, Joao Pedro

Analysis of real time information can be used to leverage logistic value chains and processes. It enables organizations to become more flexible and efficient. With the continued explosion of available data, challenges are aplenty for logistic companies on how to use such data for meaningful service

Sustainability assessment of food chain logistics

NARCIS (Netherlands)

Bloemhof, J.M.; Vorst, van der J.G.A.J.; Bastl, M.; Allaoui, H.

2015-01-01

Food chain logistics plays an important role in the sustainability performance of the food sector. Therefore, project SCALE (Step Change in Agri-food Logistics Ecosystems) started as a collaborative international project, aiming for tools and frameworks for the food sector to make a step change in

The Directions for Development of Logistics Management in Ukraine

Directory of Open Access Journals (Sweden)

Avramenko Elena V.

2017-09-01

Full Text Available The article is aimed at defining problems in the development of logistics management in Ukraine and identifying the main directions of the logistics development. The results of evaluation of the logistics efficiency by the World Bank on the LPI integral indicator were generalized, the dynamics of the main criteria for evaluating the efficiency of Ukrainian logistics for 2007-2016 were reviewed. The directions that will facilitate the development of logistics management in Ukraine have been formed according to the research by «Ukrainian Logistics Alliance».

Flexible use and technique extension of logistics management

Science.gov (United States)

Xiong, Furong

2011-10-01

As we all know, the origin of modern logistics was in the United States, developed in Japan, became mature in Europe, and expanded in China. This is a historical development of the modern logistics recognized track. Due to China's economic and technological development, and with the construction of Shanghai International Shipping Center and Shanghai Yangshan International Deepwater development, China's modern logistics industry will attain a leap-forward development of a strong pace, and will also catch up with developed countries in the Western modern logistics level. In this paper, the author explores the flexibility of China's modern logistics management techniques to extend the use, and has certain practical and guidance significances.

Dari 'Logistic Management' Menuju 'Supply Chain Management' Dan Technology

OpenAIRE

Irawan, Judith Felicia

2003-01-01

To procure materials, maintain in-process inventory and delivery products to customers, companies provided traditional logistics activities. Operational traditional logistics included inbound logistics, intern logistics and outbound logistics, the flow of physical goods, are being managed separately. In the time being, companies cannot handle many problems such as customer service satisfaction. To solve many problems, synchronized management of the flow of physical goods and associated inform...

Multivariate semi-logistic distribution and processes | Umar | Journal ...

African Journals Online (AJOL)

Multivariate semi-logistic distribution is introduced and studied. Some characterizations properties of multivariate semi-logistic distribution are presented. First order autoregressive minification processes and its generalization to kth order autoregressive minification processes with multivariate semi-logistic distribution as ...

Understanding logistic regression analysis.

Science.gov (United States)

Sperandei, Sandro

2014-01-01

Logistic regression is used to obtain odds ratio in the presence of more than one explanatory variable. The procedure is quite similar to multiple linear regression, with the exception that the response variable is binomial. The result is the impact of each variable on the odds ratio of the observed event of interest. The main advantage is to avoid confounding effects by analyzing the association of all variables together. In this article, we explain the logistic regression procedure using examples to make it as simple as possible. After definition of the technique, the basic interpretation of the results is highlighted and then some special issues are discussed.

Aerial Logistics Management for Carrier Onboard Delivery

Science.gov (United States)

2016-09-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS AERIAL LOGISTICS MANAGEMENT FOR CARRIER ONBOARD DELIVERY by Samuel L. Chen September 2016...AND SUBTITLE AERIAL LOGISTICS MANAGEMENT FOR CARRIER ONBOARD DELIVERY 5. FUNDING NUMBERS 6. AUTHOR(S) Samuel L. Chen 7. PERFORMING ORGANIZATION NAME(S...delivery (COD) is the use of aircraft to transport people and cargo from a forward logistics site (FLS) to a carrier strike group (CSG). The goal of

NATO Logistics Handbook

National Research Council Canada - National Science Library

2007-01-01

...), is intended as a simple guide to logistics in NATO. It does not attempt to examine current issues or provide answers to the problems that logisticians will face, but it rather aims at introducing them to some of the basic principles, policies...

Differential protection by cell wall components of Lactobacillus amylovorus DSM 16698Tagainst alterations of membrane barrier and NF-kB activation induced by enterotoxigenic F4+ Escherichia coli on intestinal cells.

Science.gov (United States)

Roselli, Marianna; Finamore, Alberto; Hynönen, Ulla; Palva, Airi; Mengheri, Elena

2016-09-29

The role of Lactobacillus cell wall components in the protection against pathogen infection in the gut is still largely unexplored. We have previously shown that L. amylovorus DSM 16698 T is able to reduce the enterotoxigenic F4 + Escherichia coli (ETEC) adhesion and prevent the pathogen-induced membrane barrier disruption through the regulation of IL-10 and IL-8 expression in intestinal cells. We have also demonstrated that L. amylovorus DSM 16698 T protects host cells through the inhibition of NF-kB signaling. In the present study, we investigated the role of L. amylovorus DSM 16698 T cell wall components in the protection against F4 + ETEC infection using the intestinal Caco-2 cell line. Purified cell wall fragments (CWF) from L. amylovorus DSM 16698 T were used either as such (uncoated, U-CWF) or coated with S-layer proteins (S-CWF). Differentiated Caco-2/TC7 cells on Transwell filters were infected with F4 + ETEC, treated with S-CWF or U-CWF, co-treated with S-CWF or U-CWF and F4 + ETEC for 2.5 h, or pre-treated with S-CWF or U-CWF for 1 h before F4 + ETEC addition. Tight junction (TJ) and adherens junction (AJ) proteins were analyzed by immunofluorescence and Western blot. Membrane permeability was determined by phenol red passage. Phosphorylated p65-NF-kB was measured by Western blot. We showed that both the pre-treatment with S-CWF and the co- treatment of S-CWF with the pathogen protected the cells from F4 + ETEC induced TJ and AJ injury, increased membrane permeability and activation of NF-kB expression. Moreover, the U-CWF pre-treatment, but not the co-treatment with F4 + ETEC, inhibited membrane damage and prevented NF-kB activation. The results indicate that the various components of L. amylovorus DSM 16698 T cell wall may counteract the damage caused by F4 + ETEC through different mechanisms. S-layer proteins are essential for maintaining membrane barrier function and for mounting an anti-inflammatory response against F4 + ETEC infection. U-CWF are

Standards for Standardized Logistic Regression Coefficients

Science.gov (United States)

Menard, Scott

2011-01-01

Standardized coefficients in logistic regression analysis have the same utility as standardized coefficients in linear regression analysis. Although there has been no consensus on the best way to construct standardized logistic regression coefficients, there is now sufficient evidence to suggest a single best approach to the construction of a…

Problems of logistic systems sustainable development in delivery chains

Directory of Open Access Journals (Sweden)

2011-12-01

Full Text Available Background: Realization of supply chains management paradigm, covering significantly more volumes of logistic space, logically leads to complication of logistic systems, which, in its turn, arises significant number of problems of both theoretical and practical character. In our opinion, not all the aspects of logistic systems design and their sustainable functioning have received by the present time corresponding coverage in scientific literature. More detailed consideration requires specific problems of logistic systems interaction with their environment. We can talk about formation of new scientific direction (which we suggest to name logistic environics, being applied addition to classical approach to design of logistic systems. Methods: the formalized description of interaction process for logistic systems with the environment was presented and discussed  from ecological, social, economical, organizational and technological, technical, natural scientific positions. Results and conclusions: There is an interaction between logistics systems and the environment, but formalized description of logistic systems interaction process with the environment requires performance of complex interdisciplinary research from many different positions.

Characteristics of Logistics Outsourcing in Bulgaria: The Perspectives of the Logistics Service Providers and their Customers

Directory of Open Access Journals (Sweden)

Rakovska Miroslava

2016-10-01

Full Text Available The increased demand and supply of logistics services bring together the logistics service providers (LSPs and the companies that outsource logistics activities. LSPs stand in between those companies and their customers, thus playing an essential role for supply chain integration. If the two parties have different viewpoints of the processes in the supply chain, the fulfillment of the goal to satisfy the end customers may be hindered. The purpose of this article is two-fold: First, to investigate the characteristics of logistics outsourcing in Bulgaria from the perspectives of the logistics service providers and their customers, and more specifically, to compare their viewpoints concerning the motives for outsourcing, the methods and contents of communication and some relationship management aspects; Second, to assess the relations of the communication and relationship management aspects to customer satisfaction. This article is based on empirical data provided by 138 manufacturing and trading companies and 136 LSPs and collected through two structured questionnaires designed to address the researched issues. The data were analyzed using descriptive statistics and the independent samples t-test. The research found that the service related reasons for logistics outsourcing are prevailing and that LSPs overestimate, compared to manufacturing and trading companies, motives related to service, organizational capabilities and relationships, while more manufacturing and trading companies concern as important the availability of logistics assets and the provision of value-added services. The research also found that both the LSPs and their customers consider that the extent of sharing of knowledge and information essential for material flow integration is very low and that the usage of team meetings and joint teams is quite rare. Also, customers do not view their relationships with the LSPs as so collaborative as viewed by the LSPs. Furthermore, the

Efficient logistic regression designs under an imperfect population identifier.

Science.gov (United States)

Albert, Paul S; Liu, Aiyi; Nansel, Tonja

2014-03-01

Motivated by actual study designs, this article considers efficient logistic regression designs where the population is identified with a binary test that is subject to diagnostic error. We consider the case where the imperfect test is obtained on all participants, while the gold standard test is measured on a small chosen subsample. Under maximum-likelihood estimation, we evaluate the optimal design in terms of sample selection as well as verification. We show that there may be substantial efficiency gains by choosing a small percentage of individuals who test negative on the imperfect test for inclusion in the sample (e.g., verifying 90% test-positive cases). We also show that a two-stage design may be a good practical alternative to a fixed design in some situations. Under optimal and nearly optimal designs, we compare maximum-likelihood and semi-parametric efficient estimators under correct and misspecified models with simulations. The methodology is illustrated with an analysis from a diabetes behavioral intervention trial. © 2013, The International Biometric Society.

Serum Antibodies Protect against Intraperitoneal Challenge with Enterotoxigenic Escherichia coli

Directory of Open Access Journals (Sweden)

Xinghong Yang

2011-01-01

Full Text Available To assess whether anticolonization factor antigen I (CFA/I fimbriae antibodies (Abs from enterotoxigenic Escherichia coli (ETEC can protect against various routes of challenge, BALB/c mice were immunized with a live attenuated Salmonella vaccine vector expressing CFA/I fimbriae. Vaccinated mice elicited elevated systemic IgG and mucosal IgA Abs, unlike mice immunized with the empty Salmonella vector. Mice were challenged with wild-type ETEC by the oral, intranasal (i.n., and intraperitoneal (i.p. routes. Naïve mice did not succumb to oral challenge, but did to i.n. challenge, as did immunized mice; however, vaccinated mice were protected against i.p. ETEC challenge. Two intramuscular (i.m. immunizations with CFA/I fimbriae without adjuvant conferred 100% protection against i.p. ETEC challenge, while a single 30 μg dose conferred 88% protection. Bactericidal assays showed that ETEC is highly sensitive to anti-CFA/I sera. These results suggest that parenteral immunization with purified CFA/I fimbriae can induce protective Abs and may represent an alternative method to elicit protective Abs for passive immunity to ETEC.

Crisis Management- Operational Logistics & Asset Visibility Technologies

National Research Council Canada - National Science Library

Braunbeck, Richard A; Mastria, Michael F

2006-01-01

The purpose of this MBA Project was to identify and explore logistical frameworks that leverage technology to overcome problems associated with coordinated logistics operations during crisis management...

Reference model analysis of suitability for logistics management

Directory of Open Access Journals (Sweden)

Cezary Mańkowski

2011-12-01

Full Text Available Reference models are one of the many instruments aspiring to find into a set of different concepts, methods and techniques used in managing the logistics. Therefore, the aim of this paper is to present the results of assessing the suitability of reference models for solving logistical problems. This evaluation indicates that they are universal, support the realization of all the logistics management function in various areas, such as logistics of manufacturing glass products.

Halal Logistics Implementation in Malaysia: A Practical View

Science.gov (United States)

Sham, Rohana; Zuraidah Rasi, Raja; Abdamia, Noranita; Mohamed, Suhana; Thahira Bibi, TKM

2017-08-01

Concept of halal is not only acceptable world wide by the Muslim society but also to the non Muslim. However, the implementing of halal logistics in daily operation experience a few difficulties especially on the implementation part. Although there are many academic research paper that highlight the issue of halal logistics and the critical success factor, until today, halal logistics in Malaysia is still experiencing a hiccup. This paper try to highlight a few simple ways of implementation of halal logistics that could enhance the total implementation concept at the very least cost to create benefit to all society. The Paper deals with a few aspect of possible implementation and practice to facilitate the halal logistics approach in daily operation. The main objective is to look at the possible method of implementation and critical success factors towards the implementation of halal logistics operation in daily goods movement in Malaysia.

ASSESSMENT OF LOGISTICS MANAGEMENT IN GHANA HEALTH SERVICE

Directory of Open Access Journals (Sweden)

john frimpong manso

2013-08-01

Full Text Available Ghana Public Health Sector runs a three-tier system of managing health commodities. Suppliers, the Central Medical Store, The Regional Medical Store, Service Delivery Points and the transportation system form the supply chain.  Ghana Health Service logistics system is centralized and the health care delivery system is decentralized. Logistics management in the health system is crucial. This is because there are instances where medicines and health commodities are not available at the Central Medical Stores and the Regional Medical Stores. Consequently, there is no commodity security at the service delivery points. Upon this backdrop the study seeks to assess the logistics management system in order to bring efficiency in the system. The study adopts a multi-case study approach to assess the practices of logistics management, the causes of inadequacy of logistics and the strengths and weaknesses in Ghana Health Service logistics system.  Two categories of participants that is, the key players of health logistics management and end-users were involved in the study.  Four variables; finance for procurement of health commodities, evenly distribution of health commodities, effective supervision and constant monitoring and evaluation were found crucial in effective and efficient logistics management. Moreover, it was found that poor procurement planning and budgeting, lack of financial resources for procurement, poor quantification and forecasting, delay in procurement process and order processing, and delay in receiving insurance claims are some of the causes of inadequacy of logistics in the health systems. It is recommended that Ghana Health Service logistics or supply system must receive constant monitoring and evaluation. Further, Ghana Health Service must ensure that there is effective top-down supervision in the system to bring up efficiency. Again, Ghana Health Service and Ministry of Health must ensure enough funds are secured from the

Space Station - An integrated approach to operational logistics support

Science.gov (United States)

Hosmer, G. J.

1986-01-01

Development of an efficient and cost effective operational logistics system for the Space Station will require logistics planning early in the program's design and development phase. This paper will focus on Integrated Logistics Support (ILS) Program techniques and their application to the Space Station program design, production and deployment phases to assure the development of an effective and cost efficient operational logistics system. The paper will provide the methodology and time-phased programmatic steps required to establish a Space Station ILS Program that will provide an operational logistics system based on planned Space Station program logistics support.

MANAGING INNOVATION PROJECTS USING DISTRIBUTION LOGISTICS

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Erika Loučanová

2015-12-01

Full Text Available A significant part of innovation projects management is the distribution logistics. From the point of view of time and material content, the properly chosen way of distribution is one of many factors for success of the project and innovation creation itself. The paper points out the fundamental basis of innovation management in the stage of its realization referring to the importance of distribution logistics in this part of innovation project management. Distribution logistics in the project management provides comprehensive solutions to efficiency of tangible relocating processes in all connections and mutual relations of project in order to maintain compliance between economy and business when implementing innovations.

Challenges of information technology and supply chain management in logistic sector: with an overview of Quehenberger logistics in Macedonia

OpenAIRE

Temjanovski, Riste

2014-01-01

Abstract— The Logistics and freight transport industries are ones of the most dynamic and important sectors of each economy. Logistics provides a vital “backbone” function in supporting macroeconomic processes and the operation of markets, critical infrastructures and distribution to both business and consumers, which extended much more with process of globalization. Every contemporary logistic company is conducted by the quality and precious with IT technologies in supply chain manage...

Wine industry logistics in Republic of Macedonia

OpenAIRE

Ivanova, Violeta; Atanasoski, Drasko

2013-01-01

The theoretical characteristics of logistics and logistics systems are numerous, with specific characteristics, different implications and missions. Logistics activities in the wine industry are very important. Macedonia is a large exporter of wine. In terms of export value of agricultural products in Macedonia, wine is at the first place in terms of exports of alcoholic beverages, and at the second place immediately after the tobacco. The winemaking in Macedonia is continuously increasing, e...

Logistics & Fintech: from direct benefits to big impacts

OpenAIRE

2017-01-01

This whitepaper is the result of the Logistics & Fintech programme, focusing on exchanging knowledge, promoting interest and creating collaboration opportunities between the fintech and logistics industries. This whitepaper presents our vision of financial innovation for the logistics industry, with best practices and future developments.

Web-Based Naval Fleet Logistics Information System

National Research Council Canada - National Science Library

Li, Yanfeng

2007-01-01

.... This project proposes the implementation of a Web-Based Logistics Information System to act as a single platform for Naval supply chain and shipboard customers for effective logistics planning...

Perceived barriers to pediatrician and family practitioner participation in pediatric clinical trials: Findings from the Clinical Trials Transformation Initiative.

Science.gov (United States)

Greenberg, Rachel G; Corneli, Amy; Bradley, John; Farley, John; Jafri, Hasan S; Lin, Li; Nambiar, Sumathi; Noel, Gary J; Wheeler, Chris; Tiernan, Rosemary; Smith, P Brian; Roberts, Jamie; Benjamin, Daniel K

2018-03-01

Despite legislation to stimulate pediatric drug development through clinical trials, enrolling children in trials continues to be challenging. Non-investigator (those who have never served as a clinical trial investigator) providers are essential to recruitment of pediatric patients, but little is known regarding the specific barriers that limit pediatric providers from participating in and referring their patients to clinical trials. We conducted an online survey of pediatric providers from a wide variety of practice types across the United States to evaluate their attitudes and awareness of pediatric clinical trials. Using a 4-point Likert scale, providers described their perception of potential barriers to their practice serving as a site for pediatric clinical trials. Of the 136 providers surveyed, 52/136 (38%) had previously referred a pediatric patient to a trial, and only 17/136 (12%) had ever been an investigator for a pediatric trial. Lack of awareness of existing pediatric trials was a major barrier to patient referral by providers, in addition to consideration of trial risks, distance to the site, and time needed to discuss trial participation with parents. Overall, providers perceived greater challenges related to parental concerns and parent or child logistical barriers than study implementation and ethics or regulatory barriers as barriers to their practice serving as a trial site. Providers who had previously been an investigator for a pediatric trial were less likely to be concerned with potential barriers than non-investigators. Understanding the barriers that limit pediatric providers from collaboration or inhibit their participation is key to designing effective interventions to optimize pediatric trial participation.

Effective factors contraceptive use by logistic regression model in Tehran, 1996

Directory of Open Access Journals (Sweden)

Ramezani F

1999-07-01

Full Text Available Despite unwillingness to fertility, about 30% of couples do not use any kind of contraception and this will lead to unwanted pregnancy. In this clinical trial study, 4177 subjects who had at least one alive child, and delivered in one of the 12 university hospitals in Tehran were recruited. This study was conducted in 1996. The questionnaire included some questions about contraceptive use, their attitudes about unwantedness or wantedness of their current pregnancies. Data were analysed using a Logistic Regrassion Model. Results showed that 20.3% of those who had no fertility intention, did not use any kind of contraception methods, 41.1% of the subjects who were using a contraception method before pregnancy, had got pregnant unwantedly. Based on Logistic Regression Model; age, education, previous familiarity of women with contraception methods and husband's education were the most significant factors in contraceptive use. Subjects who were 20 years old and less or 35 years old and more and illeterate subjects were at higher risk for unuse of contraception methods. This risk was not related to the gender of their children that suggests a positive change in their perspectives towards sex and the number of children. It is suggested that health politicians choose an appropriate model to enhance the literacy, education and counseling for the correct usage of contraceptives and prevention of unwanted pregnancy.

State of Logistics – an overview of logistics in South Africa

CSIR Research Space (South Africa)

Ittmann, HW

2010-09-01

Full Text Available Logistics and supply chain management play a big role in any economy and are a critical contributor to the competitiveness of a country. The demand for products can only be satisfied through the proper and cost-effective delivery of goods...

Logistics and Planning of Output Volume

Directory of Open Access Journals (Sweden)

V. I. Pokhabov

2005-01-01

Full Text Available On the basis of logistics conception the paper considers an adaptation of an enterprise to environmental changes with due account of its emergement properties. Taking into account emergement properties of an enterprise a logistics method for planning an optimum movement of the material flow is proposed in the paper.

Getting logistics closer to end users

NARCIS (Netherlands)

Luis, J.G.; Hernández, J.G.; Rodriguez, G.P.; Carcel, G.H.; Hofman, W.

2014-01-01

Nowadays, logistics could make you purchase a book in Amazon and delivering it in 24-hours using a service from a logistics operator or a transport company. In a more complex scenario, an order could be traveling around the globe, passing from hand to hand between unknown actors for months. In most

Lactobacillus zeae protects Caenorhabditis elegans from enterotoxigenic Escherichia coli-caused death by inhibiting enterotoxin gene expression of the pathogen.

Directory of Open Access Journals (Sweden)

Mengzhou Zhou

Full Text Available BACKGROUND: The nematode Caenorhabditis elegans has become increasingly used for screening antimicrobials and probiotics for pathogen control. It also provides a useful tool for studying microbe-host interactions. This study has established a C. elegans life-span assay to preselect probiotic bacteria for controlling K88(+ enterotoxigenic Escherichia coli (ETEC, a pathogen causing pig diarrhea, and has determined a potential mechanism underlying the protection provided by Lactobacillus. METHODOLOGY/PRINCIPAL FINDINGS: Life-span of C. elegans was used to measure the response of worms to ETEC infection and protection provided by lactic acid-producing bacteria (LAB. Among 13 LAB isolates that varied in their ability to protect C. elegans from death induced by ETEC strain JG280, Lactobacillus zeae LB1 offered the highest level of protection (86%. The treatment with Lactobacillus did not reduce ETEC JG280 colonization in the nematode intestine. Feeding E. coli strain JFF4 (K88(+ but lacking enterotoxin genes of estA, estB, and elt did not cause death of worms. There was a significant increase in gene expression of estA, estB, and elt during ETEC JG280 infection, which was remarkably inhibited by isolate LB1. The clone with either estA or estB expressed in E. coli DH5α was as effective as ETEC JG280 in killing the nematode. However, the elt clone killed only approximately 40% of worms. The killing by the clones could also be prevented by isolate LB1. The same isolate only partially inhibited the gene expression of enterotoxins in both ETEC JG280 and E. coli DH5α in-vitro. CONCLUSIONS/SIGNIFICANCE: The established life-span assay can be used for studies of probiotics to control ETEC (for effective selection and mechanistic studies. Heat-stable enterotoxins appeared to be the main factors responsible for the death of C. elegans. Inhibition of ETEC enterotoxin production, rather than interference of its intestinal colonization, appears to be the

Comparison of the binary logistic and skewed logistic (Scobit) models of injury severity in motor vehicle collisions.

Science.gov (United States)

Tay, Richard

2016-03-01

The binary logistic model has been extensively used to analyze traffic collision and injury data where the outcome of interest has two categories. However, the assumption of a symmetric distribution may not be a desirable property in some cases, especially when there is a significant imbalance in the two categories of outcome. This study compares the standard binary logistic model with the skewed logistic model in two cases in which the symmetry assumption is violated in one but not the other case. The differences in the estimates, and thus the marginal effects obtained, are significant when the assumption of symmetry is violated. Copyright © 2015 Elsevier Ltd. All rights reserved.

Facilitating Automation Development in Internal Logistics Systems

OpenAIRE

Granlund, Anna

2014-01-01

The internal logistics system includes all activities connected with managing the flow of materials within the physical limits of a facility. This system is an important part of operations in need of increased focus and continuous improvements. Automation is one possible tool with a previously confirmed great potential to improve internal logistics. Despite this great potential and a growing trend of using automation in the area, internal logistics activities are still not automated to the sa...

IMPORTANCE OF LOGISTICS OPERATORS IN INTERNATIONAL MARKET

OpenAIRE

KATARZYNA GRONDYS; RUZENA LOVASOVA; ANNA STELMASZCZYK; WIKTOR JANIK

2014-01-01

The aim of the article is to present role and importance of logistics operations in international arena. The article focuses on forms of outsourcing in logistics and their evolution over the years. The article discusses in detail the scope of logistics operators' activities on global scale over several years. Article also presents results of research, their analysis according to the sector of activities, their percentage share and financial benefits of using 3PL service providers. The progres...

INFORMATION SECURITY IN LOGISTICS COOPERATION

Directory of Open Access Journals (Sweden)

Tomasz Małkus

2015-03-01

Full Text Available Cooperation of suppliers of raw materials, semi-finished products, finished products, wholesalers, retailers in the form of the supply chain, as well as outsourcing of specialized logistics service require ensuring adequate support of information. It concerns the use of appropriate computer tools. The security of information in such conditions of collaboration becomes the important problem for parties of contract. The objective of the paper is to characterize main issues relating to security of information in logistics cooperation.

Proceedings of China modern logistics engineering inheritance, wisdom, innovation and cooperation

CERN Document Server

2015-01-01

Proceedings of China Modern Logistics Engineering covers nearly all areas of logistics engineering technology, focusing on the latest findings and the following theoretical aspects: Logistics Systems and Management Research; Green Logistics and Emergency Logistics; Enterprise Logistics; Material Handling; Warehousing Technology Research; Supply Chain Management; Logistics Equipment; Logistics Packaging Technology; Third-party Logistics, etc. The book will help readers to grasp the relevant aspects of the theory involved, research and development trends, while also offering guidance for their work and related studies. It is intended for researchers, scholars and graduate students in logistics management, logistics engineering, transportation, business administration, E-commerce and industrial engineering.

Analysis of Logistics Costs of the Ukrainian Semiconductor Industry

Directory of Open Access Journals (Sweden)

Popova Viktoriya D.

2014-01-01

Full Text Available The goal of the article is analysis of logistics costs in production of semiconductor materials using example of two Ukrainian enterprises. The article studies influence of logistics management and logistics costs upon formation of the final cost value (price of a commodity (service. It gives an assessment of logistics costs of Ukrainian semiconductor enterprises and establishes its structure by types of main expenditure items: material, transport, production and storehouse. It establishes the generalised quantitative structure of logistics costs of Ukrainian semiconductor enterprises with various forms of ownership under conditions of a situational growth of cost value of products and reduction of profitability of production, caused by common crisis tendencies in economy. Prospects of further studies in this direction are analysis of costs in production of semiconductor products and establishment of the specific feature of their grouping and classifying from the point of view of logistics and justification of the model of assessment of cost value of products, which takes into account mutually contradictory influence of direct logistics costs and logistics management upon the final result.

Customer satisfaction with the quality of the logistic services

Directory of Open Access Journals (Sweden)

Małgorzata Lisińska-Kuśnierz

2014-03-01

Full Text Available Background: Logistics services are evaluated mainly by measuring customer satisfaction. Measurement of the customer satisfaction provides the information about how organizations operate as well as how to effectively satisfy customer needs. The aim of this paper is to propose an evaluation model of the customer satisfaction of the quality of the logistic services provided. The research in this paper was focused on the evaluation of the level of customer satisfaction in the context of logistics service as well as on the analysis of importance of ten logistic services attributes influencing customer satisfaction. Methods: The research was conducted on the basis of the questionnaire designed for purchasers of logistic services. The subjects of the research were companies which are using refrigerated transport. Results: To define relation between level of customer satisfaction in the context of logistic service and logistic service attributes impacting this satisfaction Pearson's correlation method was used. In turn the model to evaluate the customer satisfaction in the context of logistic services in scope of refrigerated transport was built using multiple regression and stepwise regression methods.

Logistics and Inventory System -

Data.gov (United States)

Department of Transportation — The Logistics and Inventory System (LIS) is the agencys primary supply/support automation tool. The LIS encompasses everything from order entry by field specialists...

Integrated Computer System of Management in Logistics

Science.gov (United States)

Chwesiuk, Krzysztof

2011-06-01

This paper aims at presenting a concept of an integrated computer system of management in logistics, particularly in supply and distribution chains. Consequently, the paper includes the basic idea of the concept of computer-based management in logistics and components of the system, such as CAM and CIM systems in production processes, and management systems for storage, materials flow, and for managing transport, forwarding and logistics companies. The platform which integrates computer-aided management systems is that of electronic data interchange.

Logistics. Crucial link

International Nuclear Information System (INIS)

Wells, M.

1996-01-01

The article relates to offshore cost reduction in the UK and Norwegian sectors. Improvements within logistics and industrial co-operation are discussed being inspired by the joint government and industry NORSOK programme and the similar UK CRINE programme. Examples on cost reduction in various projects are given. 1 fig

International Trade Logistic Services Competitiveness in the Pacific Basin

Directory of Open Access Journals (Sweden)

América Ivonne Zamora Torres

2014-06-01

Full Text Available The development of efficient logistics plays a crucial role in national trade competitiveness. The present study aims to determine Mexico´s foreign trade logistics competitiveness with respect to the largest economies of the Asia-Pacific Economic Cooperation in 2012. The study considers three key variables: customs, international transport and logistics services. It uses a principal components analysis to compute a foreign trade logistics competitiveness index. The results indicate that the three variables have a direct and significant impact on international trade logistics competitiveness. According to the analyzed variables, the most competitive countries are, in descending order, Panama, China, Singapore, Korea and Thailand. The study identifies improvement opportunities for Mexico on the logistics and customs factors.

The Multinational Logistics Joint Task Force (MLJTF)

National Research Council Canada - National Science Library

Higginbotham, Matthew T

2007-01-01

In this monograph, by analyzing the UN, NATO and the US Army's evolving Modular Logistics Doctrine, the author integrates the key areas from each doctrine into a multinational logistics joint task force (MLJTF) organization...

Seasonality and the logistic map

International Nuclear Information System (INIS)

Silva, Emily; Peacock-Lopez, Enrique

2017-01-01

Nonlinear difference equations, such as the logistic map, have been used to study chaos and also to model population dynamics. Here we propose a model that extends the “lose + lose = win” behavior found in Parrondo’s Paradox, where switching between chaotic parameters in the logistic map yields periodic behavior (“chaos + chaos = order”). The model uses twelve parameters each reflecting the conditions of one of the twelve months. In this paper we study the effects of smooth-transitioning parameters and the robust system that emerges.

Comparison of bacterial culture and qPCR testing of rectal and pen floor samples as diagnostic approaches to detect enterotoxic Escherichia coli in nursery pigs

DEFF Research Database (Denmark)

Weber, N. R.; Nielsen, J. P.; Hjulsager, Charlotte Kristiane

2017-01-01

Enterotoxigenic E. coli (ETEC) are a major cause of diarrhoea in weaned pigs. The objective of this study was to evaluate the agreement at pen level among three different diagnostic approaches for the detection of ETEC in groups of nursery pigs with diarrhoea. The diagnostic approaches used were...... to determine the quantity of F18 and F4 genes. The study was carried out in three Danish pig herds and included 31 pens with a pen-level diarrhoea prevalence of > 25%, as well as samples from 93 diarrhoeic nursery pigs from these pens. All E. coli isolates were analysed by PCR and classified as ETEC when genes...... was observed between the detection of ETEC by bacterial culture and qPCR in the same pen floor sample in 26 (83.9%, Kappa = 0.679) pens. Conclusion: We observed an acceptable agreement for the detection of ETEC-positive diarrhoeic nursery pigs in pen samples for both bacterial culture of pen floor samples...

Predicting hypothetical willingness to participate (WTP) in a future phase III HIV vaccine trial among high-risk adolescents.

Science.gov (United States)

Giocos, Georgina; Kagee, Ashraf; Swartz, Leslie

2008-11-01

The present study sought to determine whether the Theory of Planned Behaviour predicted stated hypothetical willingness to participate (WTP) in future Phase III HIV vaccine trials among South African adolescents. Hierarchical logistic regression analyses showed that The Theory of Planned Behaviour (TPB) significantly predicted WTP. Of all the predictors, Subjective norms significantly predicted WTP (OR = 1.19, 95% C.I. = 1.06-1.34). A stepwise logistic regression analysis revealed that Subjective Norms (OR = 1.19, 95% C.I. = 1.07-1.34) and Attitude towards participation in an HIV vaccine trial (OR = 1.32, 95% C.I. = 1.00-1.74) were significant predictors of WTP. The addition of Knowledge of HIV vaccines and HIV vaccine trials, Perceived self-risk of HIV infection, Health-promoting behaviours and Attitudes towards HIV/AIDS yielded non-significant results. These findings provide support for the Theory of Reasoned Action (TRA) and suggest that psychosocial factors may play an important role in WTP in Phase III HIV vaccine trials among adolescents.

Logistics of Guinea worm disease eradication in South Sudan.

Science.gov (United States)

Jones, Alexander H; Becknell, Steven; Withers, P Craig; Ruiz-Tiben, Ernesto; Hopkins, Donald R; Stobbelaar, David; Makoy, Samuel Yibi

2014-03-01

From 2006 to 2012, the South Sudan Guinea Worm Eradication Program reduced new Guinea worm disease (dracunculiasis) cases by over 90%, despite substantial programmatic challenges. Program logistics have played a key role in program achievements to date. The program uses disease surveillance and program performance data and integrated technical-logistical staffing to maintain flexible and effective logistical support for active community-based surveillance and intervention delivery in thousands of remote communities. Lessons learned from logistical design and management can resonate across similar complex surveillance and public health intervention delivery programs, such as mass drug administration for the control of neglected tropical diseases and other disease eradication programs. Logistical challenges in various public health scenarios and the pivotal contribution of logistics to Guinea worm case reductions in South Sudan underscore the need for additional inquiry into the role of logistics in public health programming in low-income countries.

Service Innovation and Sustainability in the Danish Logistics Sector

DEFF Research Database (Denmark)

Gammelgaard, Britta; Prockl, Günter; Thordardottir, Kristin

2012-01-01

in the logistics sector, but also that a sustainability profile is not used as a driver for marketing new sustainable logistics services. The customers, on the other hand, are focused on price, geographical coverage and reliability of delivery. This study reports a portion of survey results that cover more issues......Sustainability in the logistics sector is much talked about, but at the same time there is little overview of the current activities. This paper provides an input to such an overview of logistics services provided in the Danish logistics sector in 2011. The purpose of the study is also...... to investigate driving forces of development towards sustainable logistics services from the industry. The paper is descriptive and based on an online survey sent to managing directors of 201 companies in the Danish logistics sector. The survey questions were developed on the basis of literature studies...

Molecular Characterization of Enterotoxin-Producing Escherichia coli Collected in 2011-2012, Russia.

Directory of Open Access Journals (Sweden)

Nikolay N Kartsev

Full Text Available Enterotoxin-producing Escherichia coli (ETEC are one of the main causative agents of diarrhea in children especially in developing countries and travel diarrhoea in adults. Pathogenic properties of ETEC associated with their ability to produce a heat-stable (ST and/or heat-labile (LT enterotoxins, as well as adhesins providing bacterial adhesion to intestinal epithelial cells. This study presents the molecular characterization of the ETEC isolates collected from the Central and Far-Eastern regions of Russia in 2011-2012. It was shown that all ETEC under study (n=18 had the heat-labile enterotoxin-coding operon elt, and had no the genes of the heat-stable enterotoxin operon est. DNA sequencing revealed two types of nucleotide exchanges in the eltB gene coding subunit B of LT in isolates collected from Cherepovets city (Central region, Russia and Vladivostok city (Far-East region, Russia. Only one ETEC strain carried genes cfaA, cfaB, cfaC and cfaD coding adhesion factor CFA/I. Expression of LT in four ETEC isolates in the agglutination reaction was detected using a latex test-system. The isolates were assigned to serogroups O142 (n = 6, О6 (n = 4, О25 (n = 5, О26 (n = 2, and O115 (n = 1. Genotyping showed that they belonged to an earlier described sequence-type ST4 (n = 3 as well as to 11 novel sequence-types ST1043, ST1312, ST3697, ST3707, ST3708, ST3709, ST3710, ST3755, ST3756, ST3757 and ST4509. The ETEC isolates displayed different levels of antimicrobial resistance. Eight isolates were resistant to only one drug, three isolates-to two drugs, one isolate-to three drugs, two isolates-to four antibacterials, and only one isolate to each of the five, six and ten antibacterials simultaneously. Genetic determinants of the resistance to beta-lactams and other classes of antibacterials on the ETEC genomes were identified. There are blaTEM (n = 10, blaCTX-M-15 (n = 1, class 1 integron (n = 3 carrying resistance cassettes to aminoglycosides and

Molecular Characterization of Enterotoxin-Producing Escherichia coli Collected in 2011-2012, Russia.

Science.gov (United States)

Kartsev, Nikolay N; Fursova, Nadezhda K; Pachkunov, Dmitry M; Bannov, Vasiliy A; Eruslanov, Boris V; Svetoch, Edward A; Dyatlov, Ivan A

2015-01-01

Enterotoxin-producing Escherichia coli (ETEC) are one of the main causative agents of diarrhea in children especially in developing countries and travel diarrhoea in adults. Pathogenic properties of ETEC associated with their ability to produce a heat-stable (ST) and/or heat-labile (LT) enterotoxins, as well as adhesins providing bacterial adhesion to intestinal epithelial cells. This study presents the molecular characterization of the ETEC isolates collected from the Central and Far-Eastern regions of Russia in 2011-2012. It was shown that all ETEC under study (n=18) had the heat-labile enterotoxin-coding operon elt, and had no the genes of the heat-stable enterotoxin operon est. DNA sequencing revealed two types of nucleotide exchanges in the eltB gene coding subunit B of LT in isolates collected from Cherepovets city (Central region, Russia) and Vladivostok city (Far-East region, Russia). Only one ETEC strain carried genes cfaA, cfaB, cfaC and cfaD coding adhesion factor CFA/I. Expression of LT in four ETEC isolates in the agglutination reaction was detected using a latex test-system. The isolates were assigned to serogroups O142 (n = 6), О6 (n = 4), О25 (n = 5), О26 (n = 2), and O115 (n = 1). Genotyping showed that they belonged to an earlier described sequence-type ST4 (n = 3) as well as to 11 novel sequence-types ST1043, ST1312, ST3697, ST3707, ST3708, ST3709, ST3710, ST3755, ST3756, ST3757 and ST4509. The ETEC isolates displayed different levels of antimicrobial resistance. Eight isolates were resistant to only one drug, three isolates-to two drugs, one isolate-to three drugs, two isolates-to four antibacterials, and only one isolate to each of the five, six and ten antibacterials simultaneously. Genetic determinants of the resistance to beta-lactams and other classes of antibacterials on the ETEC genomes were identified. There are blaTEM (n = 10), blaCTX-M-15 (n = 1), class 1 integron (n = 3) carrying resistance cassettes to aminoglycosides and

Optimalization of logistic costs by the controlling approach

OpenAIRE

Katarína Teplická

2007-01-01

Article deals with logistic cost problems, their following, reporting and evaluation in the firm. It gives basic information about possible access of the effective decreasing of the logistic cost by the way of controlling access, or evaluation of Balance Score Card. It indicates short algorithm of logistic costs reporting by the way of controlling.

Research on the Impact of Big Data on Logistics

Directory of Open Access Journals (Sweden)

Wang Yaxing

2017-01-01

Full Text Available In the context of big data development, a large amount of data will appear at logistics enterprises, especially in the aspect of logistics, such as transportation, warehousing, distribution and so on. Based on the analysis of the characteristics of big data, this paper studies the impact of big data on the logistics and its action mechanism, and gives reasonable suggestions. Through building logistics data center by using the big data technology, some hidden value information behind the data will be digged out, in which the logistics enterprises can benefit from it.

Logistics in 2025: Consider It DoneZ

National Research Council Canada - National Science Library

Edgell, Jaydee

1996-01-01

Accessibility replaces anxiety in 2025 logistics. Confident that logistics systems will generate what they need when they need it, commanders of aerospace forces in the year 2025 contemplate strategy and devote their energy to the battle...

Global Logistic Network of Courier Services for the 21" Century

Directory of Open Access Journals (Sweden)

Ratko Zelenika

2006-09-01

Full Text Available The development of logistics has contributed a lot to all thebranches of economy. A successful economic subject cannotexist without a well-developed logistic branch. In economicsthe organization of logistics is becoming a strategic element regardingthe policy making of enterprises. Logistics belongs to anarea that will play an important role in our lives; therefore, thedevelopment of a logistic system is of an exceptional significancefor the economy and also for the non-economic sphere ofactivities. So, modem logistics enables us to bring into line differentinterests in management of material current. Global organizersof logistic services are developing and specializing insome essential services, such as combining of cargo into assemblyconsignments and also their distribution. The biggest globaltenderers of logistic services are considered, DHL, TNT,FEDEX, UPS ...

Logistics in a low carbon concept: Connotation and realization way

Science.gov (United States)

Zheng, Chaocheng; Qiu, Xiaoying; Mao, Jiarong

2017-01-01

Low-carbon logistics has become a trend for the logistics industry-as a high-energy consumption industry, continuation of its previous operating mode has been significantly behind the times. So logistics industry must release lower carbon emissions. This paper sort out the literature home and abroad from three aspects, that is, the definition of low-carbon logistics, low-carbon logistics implementation mechanisms or measures, and low carbon design quantitative models. The research shows: low-carbon logistics needed to implemented both in enterprise' macro and micro level, which means the government should provide relevant policy support and micro enterprises should be actively sought from all sectors of the logistics in energy saving. In practice, low-carbon logistics optimization models are effective tools for enterprises to implement emission reduction.

The 5th National Logistics and Supply Chain Conference

OpenAIRE

PEKER, İskender

2016-01-01

Abstract. The 5thNational Logistics and Supply Chain Conference (ULTZK) held in Mersin Divan Hotel on the 26-28 May 2016. A number of academics, logistics service receiver company representatives (manufacturers, wholesalers, retailers, etc.), logistics service provider company representatives (transport, logistics, storage, etc.), non-governmental organization representatives, and the relevant public institution and organization representatives participated to the conducted panels and session...

The state of logistics: Research priorities for sustained improvement

Directory of Open Access Journals (Sweden)

Esbeth van Dyk

2008-11-01

Full Text Available The importance of logistics and supply chain management for the South African economy was re-emphasised by the findings of the CSIR’s third annual State of Logistics Survey. To meet current and future demands, the research agenda for logistics needs to be wider than the traditional (mainstream focus. System inefficiencies as well as specific non-traditional areas need to be explored, e.g. the integration of rural and small businesses, government service delivery, sector cooperation, and emergency logistics. This article provides a brief overview of the current state of logistics in the country and the government’s response in terms of the National Freight Logistics Strategy. Research needs, research priorities and the role of research organisations are discussed.

Performance Based Logistics - A Bridge Between Acquisition Reform and Logistics Supply Chain Management

National Research Council Canada - National Science Library

Hurst, Dana

2006-01-01

.... Performance based logistics links acquisition and supply chain management in the Total Life Cycle Systems Management and thus may provide the opportunity for true reform resulting in increased...

Knowledge Integrated Business Process Management for Third Party Logistics Companies

OpenAIRE

Zhang, Hongyan

2013-01-01

The growing importance of logistics as well as the increasing dynamic complexity of markets, technologies, and customer needs has brought great challenges to logistics. In order to focus on their core competency in such a competitive environment, more and more companies have outsourced a part or the entirety of the logistics process to third party logistics (3PL) service providers. 3PL has played a crucial role in managing logistics processes within supply chain management. Logistics processe...

Logistics and Transport - a conceptual model

DEFF Research Database (Denmark)

Jespersen, Per Homann; Drewes, Lise

2004-01-01

This paper describes how the freight transport sector is influenced by logistical principles of production and distribution. It introduces new ways of understanding freight transport as an integrated part of the changing trends of mobility. By introducing a conceptual model for understanding...... the interaction between logistics and transport, it points at ways to over-come inherent methodological difficulties when studying this relation...

Optimalization of logistic costs by the controlling approach

Directory of Open Access Journals (Sweden)

Katarína Teplická

2007-10-01

Full Text Available Article deals with logistic cost problems, their following, reporting and evaluation in the firm. It gives basic information about possible access of the effective decreasing of the logistic cost by the way of controlling access, or evaluation of Balance Score Card. It indicates short algorithm of logistic costs reporting by the way of controlling.

Logistics background study: underground mining

Energy Technology Data Exchange (ETDEWEB)

Hanslovan, J. J.; Visovsky, R. G.

1982-02-01

Logistical functions that are normally associated with US underground coal mining are investigated and analyzed. These functions imply all activities and services that support the producing sections of the mine. The report provides a better understanding of how these functions impact coal production in terms of time, cost, and safety. Major underground logistics activities are analyzed and include: transportation and personnel, supplies and equipment; transportation of coal and rock; electrical distribution and communications systems; water handling; hydraulics; and ventilation systems. Recommended areas for future research are identified and prioritized.

Logistics require savvy negotiation, patience

International Nuclear Information System (INIS)

Talboy, R.G.

1991-01-01

In the Soviet Union, logistics are affected by the extraordinary political, social and physical environment, so that operations are virtually all art, rather than science. Furthermore, this art, as it applies to a particular project, probably does not lend itself to broad generalizations about what would work somewhere else. Each project will have its own idiosyncrasies, depending on its type and location in the vast Soviet republics, and upon the personalities involved. This article discusses only the logistics that worked out and are still evolving for the project with which the author was associated

A q-deformed logistic map and its implications

International Nuclear Information System (INIS)

Banerjee, Subhashish; Parthasarathy, R

2011-01-01

A new q-deformed logistic map is proposed and it is found to have concavity in parts of the x-space. Its one-cycle and two-cycle non-trivial fixed points are obtained which are found to be qualitatively and quantitatively different from those of the usual logistic map. The stability of the proposed q-logistic map is studied using the Lyapunov exponent, and with a change in the value of the deformation parameter q, one is able to go from the chaotic to regular dynamical regime. The implications of this q-logistic map on Parrondo's paradox are examined.

Information Support of Processes in Warehouse Logistics

Directory of Open Access Journals (Sweden)

Gordei Kirill

2013-11-01

Full Text Available In the conditions of globalization and the world economic communications, the role of information support of business processes increases in various branches and fields of activity. There is not an exception for the warehouse activity. Such information support is realized in warehouse logistic systems. In relation to territorial administratively education, the warehouse logistic system gets a format of difficult social and economic structure which controls the economic streams covering the intermediary, trade and transport organizations and the enterprises of other branches and spheres. Spatial movement of inventory items makes new demands to participants of merchandising. Warehousing (in the meaning – storage – is one of the operations entering into logistic activity, on the organization of a material stream, as a requirement. Therefore, warehousing as "management of spatial movement of stocks" – is justified. Warehousing, in such understanding, tries to get rid of the perception as to containing stocks – a business expensive. This aspiration finds reflection in the logistic systems working by the principle: "just in time", "economical production" and others. Therefore, the role of warehouses as places of storage is transformed to understanding of warehousing as an innovative logistic system.

The transport performance evaluation system building of logistics enterprises

Directory of Open Access Journals (Sweden)

Xueli Wang

2013-09-01

Full Text Available Purpose: modern logistics has a significant role in today’s society, logistics cost accounts for 35% to 50% of total logistics costs, so it’s great significance to improve the transport performance of logistics enterprises. Design/methodology/approach: the authors select the transportation performance evaluation index of logistics enterprise, with the aid of the fuzzy theory and analytic hierarchy process (AHP, adopt the combining method of quantitative and qualitative analysis, construct the transport performance evaluation system of logistics enterprises. Findings: the choice of transport performance evaluation indicator system for Logistics enterprise is in a state of "high", which indicates the indicator selection is reasonable. Research limitations/implications: the selected indicators with experts’ subjective factors can not accurately quantify. Practical implications: it has important practical significance to promote the development of modern logistics enterprises and save social cost. Originality/value: current research methods mainly include the PDCA cycle model, key performance indicators (KPI and benchmarking method, principal component analysis method, etc. The authors for the first time with the aid of fuzzy theory and analytic hierarchy process (AHP, adopt the combining method of quantitative and qualitative research on transport performance problems.

Environmental logistics performance indicators affecting per capita income and sectoral growth: evidence from a panel of selected global ranked logistics countries.

Science.gov (United States)

Khan, Syed Abdul Rehman; Qianli, Dong; SongBo, Wei; Zaman, Khalid; Zhang, Yu

2017-01-01

The objective of the study is to examine the long-run and causal relationship between environmental logistics performance indicators (ELPI) and growth-specific factors in a panel of 15 selected global ranked logistics countries over a period of 2007-2015. This study is exclusive as we utilized a number of LPI factors including logistics performance, logistics competence, and logistics infrastructure with mediation of sustainable factors, i.e., carbon dioxide (CO 2 ), fossil fuel, and greenhouse gas (GHG) emissions in a region. The results show that the per capita income, industry, manufacturing, and service share to GDP is affected by CO 2 emissions and GHG emissions. Logistics competence and infrastructure promote economic growth and sectoral value added, while energy demand and FDI inflows both are prerequisite for sustainable agriculture in a region. The causal relationships confirm that more energy demand results in an increase in economic growth, industry value added, and the service sector (i.e., feedback hypothesis), while the sustainable supply chain system improves energy demand, FDI inflows, economic growth, and sectoral growth (i.e., conservation hypothesis) in a panel of countries.

AN OVERVIEW ON RETAIL REVERSE LOGISTICS

Directory of Open Access Journals (Sweden)

Ioana Olariu

2014-07-01

Full Text Available This article is a theoretical approach on retail reverse logistics. Environmental concern and the current marketing strategy have spurred retailers to implement strategies to facilitate product returns from end customers. Reverse logistics, indicating the process of this return flow, encompasses such activities as the movement of returned products, facilities to accommodate returned items, and overall remedy process for returned items. The retail industry, under great competitive pressure, has used return policies as a competitive weapon. Grocery retailers were the first to begin to focus serious attention on the problem of returns and to develop reverse logistics innovations. Grocery retailers first developed innovations such as reclamation centers. Reclamation centers, in turn, led to the establishment of centralized return centers. Centralizing returns has led to significant benefits for most firms that have implemented them. Over the last several years, retailers have consolidated. Now, more than ever, reverse logistics is seen as being important. This reverse distribution activity can be crucial to the survival of companies, because the permanent goodwill of the company is at stake. Businesses succeed because they respond to both external and internal changes and adjust in an effective manner to remain competitive.

Comparing the Discrete and Continuous Logistic Models

Science.gov (United States)

Gordon, Sheldon P.

2008-01-01

The solutions of the discrete logistic growth model based on a difference equation and the continuous logistic growth model based on a differential equation are compared and contrasted. The investigation is conducted using a dynamic interactive spreadsheet. (Contains 5 figures.)

A common language for logistics services interoperability

NARCIS (Netherlands)

Gonzalez-Rodriguez, M.; Vennesland, A.; Dalmolen, Simon

2015-01-01

Transport logistics is immersed in a world-wide changing process. The fluctuating market necessities, the distribution of production facilities, the influence of the emerging economies and the environmental compromise force transport logistics services to be as dynamic as possible, answering to

FEATURES OF LOGISTIC SYSTEM ADAPTIVE MANAGEMENT

Directory of Open Access Journals (Sweden)

Natalya VOZNENKO

2015-08-01

Full Text Available The study presents literature survey on enterprise logistic system adaptive management place and structure in the general enterprise management system. The theoretical basics of logistic system functioning, levels of its management and its effectiveness had been investigated. The role of adaptive management and its types had been scrutinized. The necessity of creating company’s adaptive regulator such as its economic mechanism had been proved.

Provincial logistics capability and economic development in South Africa

CSIR Research Space (South Africa)

Mashoko, L

2013-07-01

Full Text Available The study involves the determination of Provincial Logistics Capability for South African provinces. Provincial Logistic Capability (PLC) is the effectiveness and efficiency of a province in facilitating logistics activities both within the province...

Activities and Education in Logistics

Directory of Open Access Journals (Sweden)

Jasmina Pašagić Škrinjar

2008-03-01

Full Text Available Logistic approach to traffic means new business policy,economy and ownership, new internal organization, externaland internal communication, different corporate cultures, humanresources management using scientific methods, trainingand education, changed management type and awarding system,knowledge of information technology, communicationskills, electronic commerce, etc. Education is part of all theseelements. The introduction of logistics in all the business activitieshas been imposed due to the following reasons: because ofthe life-cycle shortening of the product and its delivery, becauseof sudden technological development, because of productionand market globalization, because of the increase in competitiveness.This paper describes first various logistic activities with theindication of practical and scientific approaches. The logisticsapproach in the traffic activities requires upgrading of the professionaland scientific level to a higher one which means additionaltraining and acquiring of new skills as well as new technologiesfor the employees.The basic aim of research was to specifY the basic logisticsactivities and problems in order to indicate the need of differentforms of education. Fast technological and social changes requireconstant improvement and modification of professionalknowledge and acqui1ing of new scientific methods and skills.

Proximity matters : synergies through co-location of logistics establishments

OpenAIRE

Heuvel, van den, F.P.; Langen, de, P.W.; Donselaar, van, K.H.; Fransoo, J.C.

2012-01-01

Although anecdotic evidence suggests that co-location of logistics activities can bring several benefits to the co-located logistics companies and hence, can be important to incorporate in the location decisions of these companies, this is the first paper to empirically research these benefits. This paper contributes to the understanding of spatial concentration of logistics firms by empirically analyzing synergies through co-location and investigates whether spatial concentration of logistic...

Logistički informacioni sistem / Logistics information system

Directory of Open Access Journals (Sweden)

Marko D. Andrejić

2010-01-01

Full Text Available Logistički automatizovani informacioni sistem treba razvijati kao deo jedinstvenog automatizovanog informacionog sistema (JAIS-a. Da bi se logistički automatizovani informacioni sistem uspešno razvijao i primenjivao u operativnoj praksi, neophodno je slediti globalni koncept razvoja JAIS-a i u razvoju više primenjivati timski rad profesionalnog informatičara i poznavaoca realnog logističkog sistema. Bitan uslov za razvoj kvalitetnog logističkog informacionog sistema jeste definisanje informacionih potreba o pojedinim objektima koje tretira logistički informacioni sistem. Zadatak logističkog automatizovanog informacionog sistema jeste da obezbedi: stalni uvid u stanje logističkog sistema; ukazivanje na potrebne i moguće mere poboljšanja; bolje planiranje i upravljanje radom realnog sistema; informisanje ljudstva o stanju realnog sistema i ukazivanje na pravce daljeg razvoja informacionih sistema. Logistički informacioni sistem treba razvijati vodeći računa i o kompatibilnosti sa budućim saveznicima i partnerima. / A logistics automated information system should be developed as a part of a unified automated information system (JAIS. In order to develop a logistics automated information system and to apply it successfully in operational use, it is necessary to follow the JAIS global development concept and rely more on teamwork of IT experts and specialists in real logistics systems. An important condition for the development of a high-quality logistics information system is to define information needs for particular objects treated by a logistics information system. The task of such a system is to provide: permanent insight into the logistics system, pointing to the necessary and possible measures for improvement, better real system planning and management activities, personnel information about the state of the real system, pointing to the directions of further system development. A logistics information system should be developed

Robust mislabel logistic regression without modeling mislabel probabilities.

Science.gov (United States)

Hung, Hung; Jou, Zhi-Yu; Huang, Su-Yun

2018-03-01

Logistic regression is among the most widely used statistical methods for linear discriminant analysis. In many applications, we only observe possibly mislabeled responses. Fitting a conventional logistic regression can then lead to biased estimation. One common resolution is to fit a mislabel logistic regression model, which takes into consideration of mislabeled responses. Another common method is to adopt a robust M-estimation by down-weighting suspected instances. In this work, we propose a new robust mislabel logistic regression based on γ-divergence. Our proposal possesses two advantageous features: (1) It does not need to model the mislabel probabilities. (2) The minimum γ-divergence estimation leads to a weighted estimating equation without the need to include any bias correction term, that is, it is automatically bias-corrected. These features make the proposed γ-logistic regression more robust in model fitting and more intuitive for model interpretation through a simple weighting scheme. Our method is also easy to implement, and two types of algorithms are included. Simulation studies and the Pima data application are presented to demonstrate the performance of γ-logistic regression. © 2017, The International Biometric Society.

Exploring logistics aspects of flood emergency measures

NARCIS (Netherlands)

de Leeuw, S.L.J.M.; Vis, I.F.A.; Jonkman, S.N.

2012-01-01

Floods are often preceded by warnings such as heavy rain that may make preparatory activities possible in order to prevent flooding from actually happening. However, flood emergency preparedness lacks insight in logistical aspects. This paper develops a framework of logistical aspects of emergency

Exploring Logistics Aspects of Flood Emergency Measures

NARCIS (Netherlands)

de Leeuw, Sander; Vis, Iris F. A.; Jonkman, Sebastiaan N.

Floods are often preceded by warnings such as heavy rain that may make preparatory activities possible in order to prevent flooding from actually happening. However, flood emergency preparedness lacks insight in logistical aspects. This paper develops a framework of logistical aspects of emergency

Assessment of laboratory logistics management information system ...

African Journals Online (AJOL)

Introduction: Logistics management information system for health commodities remained poorly implemented in most of developing countries. To assess the status of laboratory logistics management information system for HIV/AIDS and tuberculosis laboratory commodities in public health facilities in Addis Ababa. Methods: ...

Smart trade logistics - Compliance as an opportunity

NARCIS (Netherlands)

Zomer, G.R.

2011-01-01

Facilitation of trade logistics aims at simplification and harmonization of border procedures and related documentation. This is an accelerator for global trade and economic growth and therefore a priority in global trade policy. Trends in logistics and supply chain security and innovations in

State of logistics - a five-year review

CSIR Research Space (South Africa)

Ittmann, HW

2009-07-01

Full Text Available The state of logistics survey makes it possible to analyse and show trends over the past five years. This relates to quantitative and qualitative logistics issues that were not possible when this survey started in 2004. The paper will show...

Paradoxes and Opportunities in Logistic Outsourcing Research

Directory of Open Access Journals (Sweden)

Đurđica Stojanović

2012-11-01

Full Text Available Historically, very few logistic trends have caught the attention of academics and practitioners to the same extent as outsourcing. A comprehensive literature review reveals two reasons for this continual topicality. The problem complexity and the business environment dynamics – including an interaction with other main trends in logistics and modern supply chains – both led to a permanent literature gap, indicating the need to explore some new aspects of logistics outsourcing (LO. In this paper, a new LO research perspective has been explored by identifying some weaknesses in the main LO research streams and related common viewpoints which led to six ‘logistics outsourcing research paradoxes’. Each of these paradoxes is briefly described and their links with research streams and common views on LO discussed. Finally, the nature of some known opportunities for further research is better explained and some overlooked research opportunities are highlighted.

Transport costs: the dark continent of the logistics world? The impact of transport costs on book and newspaper logistics

NARCIS (Netherlands)

Runhaar, H.A.C.; Heijden, R. van der

2003-01-01

Contemporary logistics management has become more transport-intensive due, for example, to the centralisation of production and strategies aimed at reducing stocks. Transport costs are increasingly traded off against other logistical costs and seem to have lost importance in strategic decision

Marketing in the business activity of logistics service providers

Directory of Open Access Journals (Sweden)

Marcin Świtała

2013-09-01

Full Text Available Background: This article is a discussion on the role of marketing in the activity of logistics service providers. The strong competition and changing purchasing preferences should motivate the transport, forwarding and logistics sector managers to apply the marketing approach in practice. Methods: Results of direct research, conducted among a targeted group of 100 companies from the transport, forwarding and logistics sector, constitute the source basis. The sample group was divided into three categories of logistics providers: 2PL, 3PL and 4PL. The statistical analysis was based on three different non-parametric tests (Kruskal-Wallis, Chi-square and V Kramer.  Results and conclusions:  Currently, marketing does not play a key role in the activity of logistics services providers. The prevailing opinion is that importance of marketing in the company is average. The respondents have assessed in a similar way their activity compared to the activities of the competition. However, it was found that with the increase of the level of specialization (2PL-4PL, the awareness of impact of marketing on the logistics services sector also increased. The logistics services providers, who offer a wide range of logistics services, asses their competitive position in a better light.  

The challenge of defining standards of prevention in HIV prevention trials

NARCIS (Netherlands)

Philpott, Sean; Heise, Lori; McGrory, Elizabeth; Paxton, Lynn; Hankins, Catherine; Alexander, Lorraine; Apuuli, David Kihumuro; Baeten, Jared; Birx, Deborah; de Bruyn, Guy; Bukusi, Elizabeth; Burns, David; Calazans, Gabriela; Campbell, James; Caswell, Georgina; Coutinho, Alex; Dawson, Liza; Dhai, Amaboo; Dube, Samukeliso; Ecuru, Julius; Essack, Zaynab; Farley, Timothy; Gafos, Mitzy; Irungu, Pauline; Kaleebu, Pontiano; Kamali, Anatoli; Kestelyn, Evelyne; Kublin, James; Lohse, Nicolai; Lutalo, Tom; Macklin, Ruth; Mâsse, Benôıt; Mauney, Chris; McCormack, Sheena; Miller, Lori; Mfutso-Bengo, Joseph; Misra, Rajender; Muganwa, Margaret; Ndase, Patrick; Nel, Annalene; Nielsen, Leslie; Nkala, Busisiwe; O'Reilly, Kevin; Okware, Sam; Paicheler, Geneviève; Rees, Helen; Rerks-Ngarm, Supachai; Ridzon, Renee; Rosenberg, Zeda; Singh, Jerome

2011-01-01

As new HIV prevention tools are developed, researchers face a number of ethical and logistic questions about how and when to include novel HIV prevention strategies and tools in the standard prevention package of ongoing and future HIV prevention trials. Current Joint United Nations Programme on

Waste acceptance and logistics

International Nuclear Information System (INIS)

Carlson, James H.

1992-01-01

There are three major components which are normally highlighted when the Civilian Radioactive Waste Management Program is discussed - the repository, the monitored retrievable storage facility, and the transportation system. These are clearly the major physical system elements and they receive the greatest external attention. However, there will not be a successful, operative waste management system without fully operational waste acceptance plans and logistics arrangements. This paper will discuss the importance of developing, on a parallel basis to the normally considered waste management system elements, the waste acceptance and logistics arrangements to enable the timely transfer of spent nuclear fuel from more than one hundred and twenty waste generators to the Federal government. The paper will also describe the specific activities the Program has underway to make the necessary arrangements. (author)

METHODS FOR DETERMINATION AND OPTIMIZATION OF LOGISTICS COSTS

OpenAIRE

Mihaela STET

2016-01-01

The paper is dealing with the problems of logistics costs, highlighting some methods for estimation and determination of specific costs for different transport modes in freight distribution. There are highlighted, besides costs of transports, the other costs in supply chain, as well as costing methods used in logistics activities. In this context, there are also revealed some optimization means of transport costs in logistics chain.

Humanitarian logistics: Review and case study of Zimbabwean experiences

Directory of Open Access Journals (Sweden)

Charles Mbohwa

2010-11-01

Full Text Available This paper reviews and presents findings on mini-case studies done on the difficulties and problems faced by humanitarian organisations in running logistics systems in Zimbabwe. Document analysis was done and this was complemented by mini-case studies and semi-structured interviews and site visits. Mini-case studies of the operations of the World Food Programme, the International Red Cross Society and the Zimbabwe Red Cross Society, the World Health Organisation, the United Nations Children's Fund and the Zimbabwean Civil Protection Organisation in Zimbabwe are discussed. These clarify the difficulties and problems faced such as the lack of trained logistics personnel, lack of access to specialised humanitarian logistics courses and research information, the difficulty in using and adapting existing logistics systems in attending to humanitarian logistics and the lack of collaborative efforts that address the area specifically. This study seeks to use primary and secondary information to inform decision-making in humanitarian logistics with possible lessons for neighbouring countries, other regions in Africa and beyond. Activities on collaborative networks that are beneficial to humanitarian logistics are also suggested.

Spine device clinical trials: design and sponsorship.

Science.gov (United States)

Cher, Daniel J; Capobianco, Robyn A

2015-05-01

Multicenter prospective randomized clinical trials represent the best evidence to support the safety and effectiveness of medical devices. Industry sponsorship of multicenter clinical trials is purported to lead to bias. To determine what proportion of spine device-related trials are industry-sponsored and the effect of industry sponsorship on trial design. Analysis of data from a publicly available clinical trials database. Clinical trials of spine devices registered on ClinicalTrials.gov, a publicly accessible trial database, were evaluated in terms of design, number and location of study centers, and sample size. The relationship between trial design characteristics and study sponsorship was evaluated using logistic regression and general linear models. One thousand six hundred thrity-eight studies were retrieved from ClinicalTrials.gov using the search term "spine." Of the 367 trials that focused on spine surgery, 200 (54.5%) specifically studied devices for spine surgery and 167 (45.5%) focused on other issues related to spine surgery. Compared with nondevice trials, device trials were far more likely to be sponsored by the industry (74% vs. 22.2%, odds ratio (OR) 9.9 [95% confidence interval 6.1-16.3]). Industry-sponsored device trials were more likely multicenter (80% vs. 29%, OR 9.8 [4.8-21.1]) and had approximately four times as many participating study centers (pdevices not sponsored by the industry. Most device-related spine research is industry-sponsored. Multicenter trials are more likely to be industry-sponsored. These findings suggest that previously published studies showing larger effect sizes in industry-sponsored vs. nonindustry-sponsored studies may be biased as a result of failure to take into account the marked differences in design and purpose. Copyright © 2015 Elsevier Inc. All rights reserved.

Space Shuttle Orbiter logistics - Managing in a dynamic environment

Science.gov (United States)

Renfroe, Michael B.; Bradshaw, Kimberly

1990-01-01

The importance and methods of monitoring logistics vital signs, logistics data sources and acquisition, and converting data into useful management information are presented. With the launch and landing site for the Shuttle Orbiter project at the Kennedy Space Center now totally responsible for its own supportability posture, it is imperative that logistics resource requirements and management be continually monitored and reassessed. Detailed graphs and data concerning various aspects of logistics activities including objectives, inventory operating levels, customer environment, and data sources are provided. Finally, some lessons learned from the Shuttle Orbiter project and logistics options which should be considered by other space programs are discussed.

The distributional properties of the family of logistic distributions ...

African Journals Online (AJOL)

The distributional properties of half logistic distribution and Type I generalized logistic distribution were studied, bringing out the L-moments (up to order four) of each of these. Skewness and Kurtosis were obtained. Keywords: Logistic distribution, L-moments ...

Logistics Services Communication

CERN Multimedia

2006-01-01

Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorisedto have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding. Logistics Services - FI Department - 79947

Logistics Services Communication

CERN Document Server

2006-01-01

Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding. Logistics Services - FI Department - 79947

Phenomenological approach to describe logistic growth and ...

Indian Academy of Sciences (India)

In this communication, different classes of phenomenological universalities of carrying capacity dependent growth processes have been proposed. The logistic as well as carrying capacity-dependent West-type allometry-based biological growths can be explained in this proposed framework. It is shown that logistic and ...

Current situation and countermeasures of port logistics park information construction

Directory of Open Access Journals (Sweden)

Zhen Liu

2013-03-01

Full Text Available Purpose: Improve work efficiency of logistics park department, and drive the economy of the park and its surrounding areas. Design/methodology/approach: Analyze the information development situation and existent questions of current national logistics park, and design proper scheme to meet the demand of port logistics park. Findings: Proposed an information construction implementation plan using technology of the Internet of things which can be applied to port logistics park. Designed a scheme for the park information construction and explained the system's implementation strategy and implementation steps. Practical implications: The proposed construction program is particularly suitable for the northwest port logistics parks in China, and also has reference function to other logistics park construction. Originality/value: Group the information construction of the logistics park into four levels, three types of users, and two requirements. The scheme is innovative and comprehensive, which can ensure the development of port logistics park.

GIS-based spatial decision support system for grain logistics management

Science.gov (United States)

Zhen, Tong; Ge, Hongyi; Jiang, Yuying; Che, Yi

2010-07-01

Grain logistics is the important component of the social logistics, which can be attributed to frequent circulation and the great quantity. At present time, there is no modern grain logistics distribution management system, and the logistics cost is the high. Geographic Information Systems (GIS) have been widely used for spatial data manipulation and model operations and provide effective decision support through its spatial database management capabilities and cartographic visualization. In the present paper, a spatial decision support system (SDSS) is proposed to support policy makers and to reduce the cost of grain logistics. The system is composed of two major components: grain logistics goods tracking model and vehicle routing problem optimization model and also allows incorporation of data coming from external sources. The proposed system is an effective tool to manage grain logistics in order to increase the speed of grain logistics and reduce the grain circulation cost.

The Cold Chain Logistics for Perishable Agricultural Products in China

OpenAIRE

Hou Yanfang; Xie Dong; Wang Jianbo

2015-01-01

This study introduces concepts of the agricultural product cold chain logistics and domestic and international researches. Also, the study discusses issues of Chinese agricultural cold chain logistics in the development process as the following aspects: the dividing of cold chain logistics market, refrigeration hardware facilities, third-party cold chain logistics development, the level of cold chain technologies, cold chain logistics professionals and the legal system and the standard system...

Co-location synergies : specialized versus diverse logistics concentration areas

NARCIS (Netherlands)

Heuvel, van den F.P.; Langen, de P.W.; Donselaar, van K.H.; Fransoo, J.C.

2012-01-01

Purpose: The purpose of this paper is to contribute to the understanding of spatial concentration of logistics firms by empirically analyzing synergies through co-location and investigating whether co-location of logistics establishments in specialized logistics concentration areas results in

Logistics management skills development: A Zimbabwean case

Directory of Open Access Journals (Sweden)

Jacobus N. Cronjé

2015-02-01

Full Text Available Background: Since logistics emerged as an applied discipline during the latter part of the 20th century, there has been an increased need for skills development in logistics and supply chain management. However, literature suggests a general shortage of educated and skilled logistics and supply chain managers worldwide. Objectives: The purpose of this article was to benchmark an in-house training programme in logistics management in the beverage industry of Zimbabwe with international best practice. Method: A case study approach was followed focusing on the programme curriculum, content and delivery. The article reports on the nature and effectiveness of the programme. The curriculum was benchmarked with skills requirements identified in literature. Relevance was evaluated based on participant perceptions over a period of 3 years using questionnaires with both closed- and open-ended questions. Results: Findings suggested that the programme offering is in line with international practice whilst it also addresses particular issues in Third World countries. Participants perceived the programme as being practical and valuable for enhancing their job performance and career development. Conclusion: The article provides a framework for evaluating logistics training programmes. Future research could include an evaluation that measures changes in on-the-job behaviour of participants.

METHODS FOR DETERMINATION AND OPTIMIZATION OF LOGISTICS COSTS

Directory of Open Access Journals (Sweden)

Mihaela STET

2016-12-01

Full Text Available The paper is dealing with the problems of logistics costs, highlighting some methods for estimation and determination of specific costs for different transport modes in freight distribution. There are highlighted, besides costs of transports, the other costs in supply chain, as well as costing methods used in logistics activities. In this context, there are also revealed some optimization means of transport costs in logistics chain.

76 FR 22681 - Defense Logistics Agency (DLA) Address Directory

Science.gov (United States)

2011-04-22

... DEPARTMENT OF DEFENSE Office of the Secretary Defense Logistics Agency (DLA) Address Directory AGENCY: Department of Defense. ACTION: Notice. SUMMARY: The Defense Logistics Agency (DLA) is updating... Directory: Defense Logistics Agency Headquarters, Andrew T. McNamara Building, 8725 John J. Kingman Road...

Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrhea.

Science.gov (United States)

Flores, Jose; DuPont, Herbert L; Paredes-Paredes, Mercedes; Aguirre-Garcia, M Magdalena; Rojas, Araceli; Gonzalez, Alexei; Okhuysen, Pablo C

2010-05-01

Enterotoxigenic Escherichia coli (ETEC), which produces heat-labile toxin (LT), is a common cause of travelers' diarrhea (TD). The B subunit of ETEC LT is immunologically related to the B subunit of Vibrio cholerae toxin (CT). In this pilot study we evaluated the whole-blood gamma interferon response to CT B in 17 U.S. adults traveling to Mexico. Only one of nine subjects who demonstrated a cellular immune response as determined by whole-blood gamma interferon production to CT B on arrival to Mexico developed diarrhea, whereas five of eight without a cellular response developed diarrhea. Markers of the cellular immune response to ETEC LT could help in identifying individuals immune to ETEC LT, and these markers deserve additional study.

Porcine aminopeptidase N binds to F4+ enterotoxigenic Escherichia coli fimbriae.

Science.gov (United States)

Xia, Pengpeng; Wang, Yiting; Zhu, Congrui; Zou, Yajie; Yang, Ying; Liu, Wei; Hardwidge, Philip R; Zhu, Guoqiang

2016-02-09

F4(+) enterotoxigenic Escherichia coli (ETEC) strains cause diarrheal disease in neonatal and post-weaned piglets. Several different host receptors for F4 fimbriae have been described, with porcine aminopeptidase N (APN) reported most recently. The FaeG subunit is essential for the binding of the three F4 variants to host cells. Here we show in both yeast two-hybrid and pulldown assays that APN binds directly to FaeG, the major subunit of F4 fimbriae, from three serotypes of F4(+) ETEC. Modulating APN gene expression in IPEC-J2 cells affected ETEC adherence. Antibodies raised against APN or F4 fimbriae both reduced ETEC adherence. Thus, APN mediates the attachment of F4(+) E. coli to intestinal epithelial cells.

Enterotoxigenic Escherichia coli Subclinical Infection in Pigs: Bacteriological and Genotypic Characterization and Antimicrobial Resistance Profiles.

Science.gov (United States)

Moredo, Fabiana A; Piñeyro, Pablo E; Márquez, Gabriela C; Sanz, Marcelo; Colello, Rocío; Etcheverría, Analía; Padola, Nora L; Quiroga, María A; Perfumo, Carlos J; Galli, Lucía; Leotta, Gerardo A

2015-08-01

Enterotoxigenic Escherichia coli (ETEC) is the major pathogen responsible for neonatal diarrhea, postweaning diarrhea, and edema disease in pigs. Although it can be harmless, ETEC is also present in the intestines of other animal species and humans, causing occasional diarrhea outbreaks. The evaluation of this pathogen's presence in food sources is becoming an increasingly important issue in human health. In order to determine the prevalence of ETEC in nondiarrheic pigs, 990 animals from 11 pig farms were sampled. Using end-time polymerase chain reaction (PCR), eltA, estI genes, or both, were detected in 150 (15.2%) animals. From the positive samples, 40 (26.6%) ETEC strains were isolated, showing 19 antibiotic-resistance patterns; 52.5% of these strains had multiple antibiotic resistances, and 17.5% carried the intI2 gene. The most prevalent genotypes were rfb(O157)/estII/aidA (32.5%) and estI/estII (25.0%). The estII gene was identified most frequently (97.5%), followed by estI (37.5%), astA (20.0%), and eltA (12.5%). The genes coding the fimbriae F5, F6, and F18 were detected in three single isolates. The aidA gene was detected in 20 ETEC strains associated with the estII gene. Among the isolated ETEC strains, stx(2e)/estI, stx(2e)/estI/estII, and stx(2e)/estI/estII/intI2 genotypes were identified. The ETEC belonged to 12 different serogroups; 37.5% of them belonged to serotype O157:H19. Isolates were grouped by enterobacterial repetitive intergenic consensus-PCR into 5 clusters with 100.0% similarity. In this study, we demonstrated that numerous ETEC genotypes cohabit and circulate in swine populations without clinical manifestation of neonatal diarrhea, postweaning diarrhea, or edema disease in different production stages. The information generated is important not only for diagnostic and epidemiological purposes, but also for understanding the dynamics and ecology of ETEC in pigs in different production stages that can be potentially transmitted to humans

Logistics hubs: an integration of transport infrastructure

CSIR Research Space (South Africa)

Botha, M

2008-07-01

Full Text Available " that have jumped on the band wagon pushing for logistics hubs to be established in their regions or within their areas of jurisdiction. The feasibility of a logistics hub is dependent on a number of criteria with access to ideally more than two...

Reverse logistics: A review of case studies

NARCIS (Netherlands)

Brito, de M.P.; Dekker, Rommert; Flapper, S.D.P.; Fleischmann, B.; Klose, A.

2004-01-01

This paper gives an overview of scientific literature that describes and discusses cases of reverse logistics activities in practice. Over sixty case studies are considered. Based on these studies we are able to indicate critical factors for the practice of reverse logistics. In addition we compare

Transport logistical effects of new traffic infrastructures

DEFF Research Database (Denmark)

Hansen, Leif Gjesing

2004-01-01

The article examines the consequences for transport and logistics reorganisation following the establishment of fixed links across Great belt and Oresund in Denmark......The article examines the consequences for transport and logistics reorganisation following the establishment of fixed links across Great belt and Oresund in Denmark...

APPLICATION OF MULTIPLE LOGISTIC REGRESSION, BAYESIAN LOGISTIC AND CLASSIFICATION TREE TO IDENTIFY THE SIGNIFICANT FACTORS INFLUENCING CRASH SEVERITY

Directory of Open Access Journals (Sweden)

MILAD TAZIK

2017-11-01

Full Text Available Identifying cases in which road crashes result in fatality or injury of drivers may help improve their safety. In this study, datasets of crashes happened in TehranQom freeway, Iran, were examined by three models (multiple logistic regression, Bayesian logistic and classification tree to analyse the contribution of several variables to fatal accidents. For multiple logistic regression and Bayesian logistic models, the odds ratio was calculated for each variable. The model which best suited the identification of accident severity was determined based on AIC and DIC criteria. Based on the results of these two models, rollover crashes (OR = 14.58, %95 CI: 6.8-28.6, not using of seat belt (OR = 5.79, %95 CI: 3.1-9.9, exceeding speed limits (OR = 4.02, %95 CI: 1.8-7.9 and being female (OR = 2.91, %95 CI: 1.1-6.1 were the most important factors in fatalities of drivers. In addition, the results of the classification tree model have verified the findings of the other models.

Perspectives of transport logistics in the railway transport enterprises

OpenAIRE

Elagin, Yu; Obruch, A.

2014-01-01

In this paper, the authors study the main directions of development of transport logistics. Identified as the main types of general transport logistics, as well as the rail sector, in which logistics acquires a dominant role in terms of reform. Also highlights the main features of transport logistics for railway transport enterprises and proved the importance of integrating function in modern conditions of development. The authors noted that to ensure the effective development of railway tran...

LOGISTICS CUSTOMER SERVICE ON THE EXAPLE OF LOGISTIC’S OPERATOR

Directory of Open Access Journals (Sweden)

Joanna WALASEK

2014-03-01

Full Text Available The article is an attempt to approach essential issues in modern logistics customer service. It shows the direct link between logistics operations and customer satisfaction before, during and after the service is provided. Third party logistics operator “GAMA” serves as an example of a successful logistics strategy appliance, which translates into high customer satisfaction. A detailed description of logistics services and the role they play in the modern market is provided.

Reverse Logistics: RFID the key to optimality

Directory of Open Access Journals (Sweden)

Rezwan Asif

2011-07-01

Full Text Available Purpose: The purpose of this paper is to find ways to reduce uncertainties in Reverse logistic supply chain (RLSC through the use of Radio-frequency identification (RFID technology.Design/methodology/approach: This paper reviews literature and builds model to relate RFID with uncertainties in order to optimize Reverse Logistics. Findings: RFID is really efficient to determine and detect quantity, variety and cycle times of returns; however it's not as convenient to determine quality of the returns. The collected information from RFID can be used to standardize the RLSC.Research limitations: Though it’s several and unique advantages some limitations of RFID have been identified in quality and processing sequence, collecting points and different standards, and in global usage.Originality/value: Previous studies in the area of Reverse Logistics and RFID don’t cover all impacts of this technology on RLSC. This review paper has investigated these impacts and offers a model for optimizing the Reverse Logistics Supply Chain.

BIM for Construction Site Logistics Management

Directory of Open Access Journals (Sweden)

K. Whitlock

2018-01-01

Full Text Available Emerging Building Information Modelling (BIM has been hailed as a revolutionary technology and information management process that facilitates collaboration and more efficient design and construction processes through innovative 3D modelling software, open access to information and multidisciplinary integration. The deadline of compliance to BIM level 2 on all public sector centrally procured construction projects has expired leaving many construction firms anxious to adopt BIM. Most common documented applications of BIM have been in the areas of architectural and structural design, quantity surveying, construction project management, and sustainability with very limited peer-reviewed studies on construction logistics management. The aim of this study is to investigate how BIM can be applied to construction logistics management. This study adopts a desk-top approach, with articles sources from renowned scientific databases such as ScienceDirect, Google Scholar and Emerald. The study culminated in the identification of benefits and barriers of adopting BIM for construction logistics management. Given only a desk-top approach has been used, the recommendation for future study is to build on this to conduct an empirical study using both qualitative and quantitative data. This will provide an in-depth understanding of the use of BIM for construction logistics management and open opportunities for further research.

Sustainable logistics and transportation optimization models and algorithms

CERN Document Server

Gakis, Konstantinos; Pardalos, Panos

2017-01-01

Focused on the logistics and transportation operations within a supply chain, this book brings together the latest models, algorithms, and optimization possibilities. Logistics and transportation problems are examined within a sustainability perspective to offer a comprehensive assessment of environmental, social, ethical, and economic performance measures. Featured models, techniques, and algorithms may be used to construct policies on alternative transportation modes and technologies, green logistics, and incentives by the incorporation of environmental, economic, and social measures. Researchers, professionals, and graduate students in urban regional planning, logistics, transport systems, optimization, supply chain management, business administration, information science, mathematics, and industrial and systems engineering will find the real life and interdisciplinary issues presented in this book informative and useful.

Segmentasi Pasar Penyedia Jasa Logistik (Third Party Logistics di Indonesia

Directory of Open Access Journals (Sweden)

Darjat Sudrajat

2010-11-01

Full Text Available Market segmentation is fundamental in marketing strategy and the first step of market-based strategy preparation, to strengthen its marketing efficiency, and creating opportunities for sales growth and profits. This also applies to market segmentation logistics service providers (TPL - Third Party Logistics, the market is highly developed in the last decade, so that the logistics service providers has to develop marketing strategies properly. The purpose of this research is to gain a better understanding of different industries that exist today and map the needs of the logistics services of TPL customers. Based on exploration research conducted, it can be found in conformities relating to the logistics industry from several companies, ie appropriateness to the complexity of logistics activities of some companies and degree of investment of TPL services company in conducting the activity. Logistics service provider market segmentation can be based on variable complexity of logistics activities, whether it is high, medium or low and variable degrees of investment in the company whether minor, major, or integrated/total. Companies in different industries can have the same logistic service requirements and companies in the same industry can have different logistic service requirements. Client companies for logistics service providers which product handling are classified as semi-complex is the most attractive customer segments for being penetrated. The industries are classified into this segment is automotive, food and beverage, animal food, ceramic, and plantation. 

An allometric scaling relation based on logistic growth of cities

International Nuclear Information System (INIS)

Chen, Yanguang

2014-01-01

Highlights: • An allometric scaling based on logistic process can be used to model urban growth. • The traditional allometry is based on exponential growth instead of logistic growth. • The exponential allometry represents a local scaling of urban growth. • The logistic allometry represents a global scaling of urban growth. • The exponential allometry is an approximation relation of the logistic allometry. - Abstract: The relationships between urban area and population size have been empirically demonstrated to follow the scaling law of allometric growth. This allometric scaling is based on exponential growth of city size and can be termed “exponential allometry”, which is associated with the concepts of fractals. However, both city population and urban area comply with the course of logistic growth rather than exponential growth. In this paper, I will present a new allometric scaling based on logistic growth to solve the above mentioned problem. The logistic growth is a process of replacement dynamics. Defining a pair of replacement quotients as new measurements, which are functions of urban area and population, we can derive an allometric scaling relation from the logistic processes of urban growth, which can be termed “logistic allometry”. The exponential allometric relation between urban area and population is the approximate expression of the logistic allometric equation when the city size is not large enough. The proper range of the allometric scaling exponent value is reconsidered through the logistic process. Then, a medium-sized city of Henan Province, China, is employed as an example to validate the new allometric relation. The logistic allometry is helpful for further understanding the fractal property and self-organized process of urban evolution in the right perspective

Logistics as a Competitive Warfighting Advantage

Science.gov (United States)

2016-10-20

to the current logistics enterprise – Inventory management and reduction Final – Approved by DBB on 20 OCT 2016 7 Findings - Supply Chain ...adversaries have “Operationalized Globalization ” Final – Approved by DBB on 20 OCT 2016 8 Recommendations - Supply Chain Resiliency -  DoD needs a...savings • Target supply chain and excess depot warehouse and capacity  Pursue other tools to leverage and or redeploy logistics assets. • Performance

Solving Complex Logistics Problems with Multi-Artificial Intelligent System

Directory of Open Access Journals (Sweden)

Y.K. Tse

2009-10-01

Full Text Available The economy, which has become more information intensive, more global and more technologically dependent, is undergoing dramatic changes. The role of logistics is also becoming more and more important. In logistics, the objective of service providers is to fulfill all customers? demands while adapting to the dynamic changes of logistics networks so as to achieve a higher degree of customer satisfaction and therefore a higher return on investment. In order to provide high quality service, knowledge and information sharing among departments becomes a must in this fast changing market environment. In particular, artificial intelligence (AI technologies have achieved significant attention for enhancing the agility of supply chain management, as well as logistics operations. In this research, a multi-artificial intelligence system, named Integrated Intelligent Logistics System (IILS is proposed. The objective of IILS is to provide quality logistics solutions to achieve high levels of service performance in the logistics industry. The new feature of this agile intelligence system is characterized by the incorporation of intelligence modules through the capabilities of the case-based reasoning, multi-agent, fuzzy logic and artificial neural networks, achieving the optimization of the performance of organizations.

Analysis of the logistics processes in the wine distribution

OpenAIRE

Slavkovský, Matúš

2011-01-01

Master's thesis is referring the importance of logistics in the retail business and the importance of reducing logistics costs. It includes so theoretical knowledge as well as the analysis of the relevant markets, which are producing and consuming wine in the largest quantities. Thesis is focused on analysis of the logistical processes and costs of an e-shop. Based on this analysis measures to improve the logistics of the process of the company are proposed. The goal of the Master's thesis is...

Principles of Logistics Applied to Railway Passenger Transport

Directory of Open Access Journals (Sweden)

Vojtek Martin

2017-01-01

Full Text Available Main challenge of logistics is delivering right assortment of products in exact amount, to exact place, in exact time, ecologically and for exact price. Logistics deals with freight transport but when the word ‘products’ is changed to ‘passengers’, then many principles can be applied to passenger transport. Railway passenger transport is the key part of passenger transport system, so it is necessary to optimize it on logistics philosophy at first.

Logistics engineering education from the point of view environment

Science.gov (United States)

Bányai, Ágota

2010-05-01

A new field of MSc programme offered by the Faculty of Mechanical Engineering and Informatics of the University of Miskolc is represented by the programme in logistics engineering. The Faculty has always laid great emphasis on assigning processes connected with environment protection and globalisation issues the appropriate weight in its programmes. This is based on the fact that the Faculty has initiated and been involved in a great number of research and development projects with a substantial emphasis on the fundamental principles of sustainable development. The objective of the programme of logistics engineering is to train engineers who, in possession of the science, engineering, economic, informatics and industrial, transportation technological knowledge related to the professional field of logistics, are able to analyse, design, organise, and control logistics processes and systems (freight transportation, materials handling, storage, commissioning, loading, purchasing, distribution and waste management) as well as to design and develop machinery and equipment as the elements of logistic systems and also to be involved in their manufacture and quality control and are able to control their operation. The programme prepares its students for performing the logistics management tasks in a company, for creative participation in solving research and development problems in logistics and for pursuing logistics studies in doctoral programmes. There are several laboratories available for practice-oriented training. The 'Integrated Logistics Laboratory' consists of various fixed and mobile, real industrial, i.e. not model-level equipment, the integration of which in one system facilitates not only the presentation, examination and development of the individual self-standing facilities, but the study of their interaction as well in terms of mechatronics, engineering, control engineering, informatics, identification technology and logistics. The state

RISK ANALYSIS AND EVALUATION FOR CRITICAL LOGISTICAL INFRASTRUCTURE

Directory of Open Access Journals (Sweden)

Sascha Düerkop

2016-12-01

Full Text Available Logistical infrastructure builds the backbone of an economy. Without an effective logistical infrastructure in place, the supply for both enterprises and consumers might not be met. But even a high-quality logistical infrastructure can be threatened by risks. Thus, it is important to identify, analyse, and evaluate risks for logistical infrastructure that might threaten logistical processes. Only if those risks are known and their impact estimated, decision makers can implement counteractive measures to reduce risks. In this article, we develop a network-based approach that allows for the evaluation of risks and their consequences onto the logistical network. We will demonstrate the relevance of this approach by applying it to the logistics network of the central German state of Hesse. Even though transport data is extensively tracked and recorded nowadays, typical daily risks, like accidents on a motorway, and extraordinary risks, like a bridge at risk to collapse, terrorist attacks or climate-related catastrophes, are not systematically anticipated. Several studies unveiled recently that the overall impact for an economy of possible failures of single nodes and/or edges in a network are not calculated, and particularly critical edges are not identified in advance. We address this information gap by a method that helps to identify and quantify risks in a given network. To reach this objective, we define a mathematical optimization model that quantifies the current “risk-related costs” of the overall network and quantify the risk by investigating the change of the overall costs in the case a risk is realized.

Prevention of abdominal wound infection (PROUD trial, DRKS00000390: study protocol for a randomized controlled trial

Directory of Open Access Journals (Sweden)

Heger Ulrike

2011-11-01

Full Text Available Abstract Background Wound infection affects a considerable portion of patients after abdominal operations, increasing health care costs and postoperative morbidity and affecting quality of life. Antibacterial coating has been suggested as an effective measure to decrease postoperative wound infections after laparotomies. The INLINE metaanalysis has recently shown the superiority of a slowly absorbable continuous suture for abdominal closure; with PDS plus® such a suture has now been made available with triclosan antibacterial coating. Methods/Design The PROUD trial is designed as a randomised, controlled, observer, surgeon and patient blinded multicenter superiority trial with two parallel groups and a primary endpoint of wound infection during 30 days after surgery. The intervention group will receive triclosan coated polydioxanone sutures, whereas the control group will receive the standard polydioxanone sutures; abdominal closure will otherwise be standardized in both groups. Statistical analysis is based on intention-to-treat population via binary logistic regression analysis, the total sample size of n = 750 is sufficient to ensure alpha = 5% and power = 80%, an interim analysis will be carried out after data of 375 patients are available. Discussion The PROUD trial will yield robust data to determine the effectiveness of antibacterial coating in one of the standard sutures for abdominal closure and potentially lead to amendment of current guidelines. The exploration of clinically objective parameters as well as quality of life holds immediate relevance for clinical management and the pragmatic trial design ensures high external validity. Trial Registration The trial protocol has been registered with the German Clinical Trials Register (DRKS00000390.

Decision-making on reverse logistics in the construction industry

Directory of Open Access Journals (Sweden)

Thanwadee Chinda

2016-02-01

Full Text Available With the growing competition, many construction organizations attempt to improve their productivity, quality, and efficiency. Construction waste management, by means of reverse logistics, becomes a key issue to improve the productivity, and raise the company’s green image. In this study, four reverse logistics methods-direct reuse, remanufacturing, recycling, and landfill-are considered to manage construction and demolition (C&D waste. Two factors (economic and site-specific with their 15 sub-factors affecting the decisions to implement the reverse logistics are examined. The hierarchy model of reverse logistics decisions, developed through the analytic hierarchy process, reveal the importance of the economic factor over the site-specific factor. It is suggested that the transportation cost, the processing cost, the specific sorting technology, and the limited project time must be first considered before making decisions on reverse logistics plans. The construction company can utilize the developed hierarchy model to decide on the most appropriate reverse logistics plan to achieve the best benefits.

LOGISTIC FUNCTION PROFILE FIT: A least-squares program for fitting interface profiles to an extended logistic function

International Nuclear Information System (INIS)

Kirchhoff, William H.

2012-01-01

The extended logistic function provides a physically reasonable description of interfaces such as depth profiles or line scans of surface topological or compositional features. It describes these interfaces with the minimum number of parameters, namely, position, width, and asymmetry. Logistic Function Profile Fit (LFPF) is a robust, least-squares fitting program in which the nonlinear extended logistic function is linearized by a Taylor series expansion (equivalent to a Newton–Raphson approach) with no apparent introduction of bias in the analysis. The program provides reliable confidence limits for the parameters when systematic errors are minimal and provides a display of the residuals from the fit for the detection of systematic errors. The program will aid researchers in applying ASTM E1636-10, “Standard practice for analytically describing sputter-depth-profile and linescan-profile data by an extended logistic function,” and may also prove useful in applying ISO 18516: 2006, “Surface chemical analysis—Auger electron spectroscopy and x-ray photoelectron spectroscopy—determination of lateral resolution.” Examples are given of LFPF fits to a secondary ion mass spectrometry depth profile, an Auger surface line scan, and synthetic data generated to exhibit known systematic errors for examining the significance of such errors to the extrapolation of partial profiles.

Intensification of Development of Mixed Transportation of Freight in Ukraine through Formation of the Network of Transportation and Logistic Centres and Transportation and Logistic Clusters

Directory of Open Access Journals (Sweden)

Karpenko Oksana O.

2013-11-01

Full Text Available Development of mixed transportation is a prospective direction of development of the transportation system of Ukraine. The article analyses the modern state of development of mixed transportation of freight in Ukraine. The most popular types of combined transportation (refers to multi-modal are container and contrailer trains, which are formed both in Ukraine (Viking and Yaroslav and in other countries, first of all, Belarus (Zubr. One of the reasons of underdevelopment of mixed transportation of freight in Ukraine is absence of a developed network of transportation and logistic centres. The article offers to form a network of transportation and logistic centres in Ukraine as a way of intensification of development of mixed transportations of freight, since they facilitate co-ordination of use of various types of transport and support integrated management of material flows. Transportation and logistic centres should become a start-up complex, around which transportation and logistic clusters would be gradually formed. Transportation and logistic clusters is a new efficient form of network organisation and management of transportation and logistic services and they also ensure growth of efficiency of use of the regional transportation and logistic potential of Ukraine. The article shows prospective supporting transportation and logistic centres and centres of formation of transportation and logistic clusters in the territory of Ukraine. Formation of efficient transportation and logistic system of Ukraine on the basis of a network of transportation and logistic clusters would facilitate entering of Ukraine into the world transportation environment and would allow acceleration of introduction of efficient logistic schemes of freight delivery, in particular, mixed transportation of freight.

An Interactive Logistics Centre Information Integration System Using Virtual Reality

Science.gov (United States)

Hong, S.; Mao, B.

2018-04-01

The logistics industry plays a very important role in the operation of modern cities. Meanwhile, the development of logistics industry has derived various problems that are urgent to be solved, such as the safety of logistics products. This paper combines the study of logistics industry traceability and logistics centre environment safety supervision with virtual reality technology, creates an interactive logistics centre information integration system. The proposed system utilizes the immerse characteristic of virtual reality, to simulate the real logistics centre scene distinctly, which can make operation staff conduct safety supervision training at any time without regional restrictions. On the one hand, a large number of sensor data can be used to simulate a variety of disaster emergency situations. On the other hand, collecting personnel operation data, to analyse the improper operation, which can improve the training efficiency greatly.

AN INTERACTIVE LOGISTICS CENTRE INFORMATION INTEGRATION SYSTEM USING VIRTUAL REALITY

Directory of Open Access Journals (Sweden)

S. Hong

2018-04-01

Full Text Available The logistics industry plays a very important role in the operation of modern cities. Meanwhile, the development of logistics industry has derived various problems that are urgent to be solved, such as the safety of logistics products. This paper combines the study of logistics industry traceability and logistics centre environment safety supervision with virtual reality technology, creates an interactive logistics centre information integration system. The proposed system utilizes the immerse characteristic of virtual reality, to simulate the real logistics centre scene distinctly, which can make operation staff conduct safety supervision training at any time without regional restrictions. On the one hand, a large number of sensor data can be used to simulate a variety of disaster emergency situations. On the other hand, collecting personnel operation data, to analyse the improper operation, which can improve the training efficiency greatly.

Marshall-Olkin multivariate semi-logistic distribution and minification ...

African Journals Online (AJOL)

Olkin multivariate logistic distribution (MO-ML) are introduced and studied. Various characterizations properties of Marshall-Olkin multivariate semi-logistic distribution are investigated and studied. First order autoregressive minification processes ...

Consumer Dispersion and Logistics Costs in Various Distribution Systems

DEFF Research Database (Denmark)

Turkensteen, Marcel; Klose, Andreas

We address the relationship between the geographical dispersion of a set of demand points and the expected logistics costs. This is relevant in the strategic marketing decision which groups of consumers to target. We devise quickly computable measures for the logistics costs. In our experiments......, dispersed sets of demand points are created. For various types of distribution systems, expected logistics costs are computed using continuous approximation, location and routing methodologies. We find that the average distance between locations is an effective estimate of the logistics costs....

Low-Carbon Warehousing: Examining Impacts of Building and Intra-Logistics Design Options on Energy Demand and the CO2 Emissions of Logistics Centers

Directory of Open Access Journals (Sweden)

Julia Freis

2016-05-01

Full Text Available Logistics centers contribute to CO2 emissions in the building and logistics sector and therefore share a responsibility to decarbonize not only the supply chain. Synergy effects in both building and intra-logistics should be considered as suitable levers to lower energy demand and related CO2 emissions. This research develops firs t with a systemic approach an integrated analytical model for energy calculation and reference building models for different types of logistics centers to provide basic knowledge and a methodological framework for planners and managers to aid in the selection of different intra-logistics and building design options for optimum energy efficiency. It then determines the energy demand in reference building models and performs parameter studies to examine interrelations and impacts of design options for intra-logistics, building technology, and building skin on energy demand. It combines these to optimized reference building models to show the extent to which energy and CO2 emission savings can be reached. The results show that it is possible to significantly lower CO2 emissions. However, there are clear differences between the different types of logistics centers and the impacts of different design options.

Humanitarian response: improving logistics to save lives.

Science.gov (United States)

McCoy, Jessica

2008-01-01

Each year, millions of people worldwide are affected by disasters, underscoring the importance of effective relief efforts. Many highly visible disaster responses have been inefficient and ineffective. Humanitarian agencies typically play a key role in disaster response (eg, procuring and distributing relief items to an affected population, assisting with evacuation, providing healthcare, assisting in the development of long-term shelter), and thus their efficiency is critical for a successful disaster response. The field of disaster and emergency response modeling is well established, but the application of such techniques to humanitarian logistics is relatively recent. This article surveys models of humanitarian response logistics and identifies promising opportunities for future work. Existing models analyze a variety of preparation and response decisions (eg, warehouse location and the distribution of relief supplies), consider both natural and manmade disasters, and typically seek to minimize cost or unmet demand. Opportunities to enhance the logistics of humanitarian response include the adaptation of models developed for general disaster response; the use of existing models, techniques, and insights from the literature on commercial supply chain management; the development of working partnerships between humanitarian aid organizations and private companies with expertise in logistics; and the consideration of behavioral factors relevant to a response. Implementable, realistic models that support the logistics of humanitarian relief can improve the preparation for and the response to disasters, which in turn can save lives.

4th International Conference on Dynamics in Logistics

CERN Document Server

Pannek, Jürgen; Thoben, Klaus-Dieter

2016-01-01

This contributed volume brings together research papers presented at the 4th International Conference on Dynamics in Logistics, held in Bremen, Germany in February 2014. The conference focused on the identification, analysis and description of the dynamics of logistics processes and networks. Topics covered range from the modeling and planning of processes, to innovative methods like autonomous control and knowledge management, to the latest technologies provided by radio frequency identification, mobile communication, and networking. The growing dynamic poses wholly new challenges: logistics processes and networks must be(come) able to rapidly and flexibly adapt to constantly changing conditions. The book primarily addresses the needs of researchers and practitioners from the field of logistics, but will also be beneficial for graduate students.

WHY DO LOGISTICS AND TRANSPORT MATTER FOR DEVELOPMENT

OpenAIRE

Nedelescu-Ionescu Daniela; Rujan Ovidiu

2014-01-01

In face of the challenges of global competition, business firms are concentrating more on the needs of customers and seeking ways to reduce costs, improve quality and meet the ever-rising expectation of their customers. To these ends, many of them have identified logistics as an area to build cost and service advantages. Logistical activities have always been vital to organizations, and therefore business logistics and supply chain management represents a synthesis of many concepts, principle...

Multiepitope fusion antigen induces broadly protective antibodies that prevent adherence of Escherichia coli strains expressing colonization factor antigen I (CFA/I), CFA/II, and CFA/IV.

Science.gov (United States)

Ruan, Xiaosai; Knudsen, David E; Wollenberg, Katie M; Sack, David A; Zhang, Weiping

2014-02-01

Diarrhea is the second leading cause of death in children younger than 5 years and continues to be a major threat to global health. Enterotoxigenic Escherichia coli (ETEC) strains are the most common bacteria causing diarrhea in developing countries. ETEC strains are able to attach to host small intestinal epithelial cells by using bacterial colonization factor antigen (CFA) adhesins. This attachment helps to initiate the diarrheal disease. Vaccines that induce antiadhesin immunity to block adherence of ETEC strains that express immunologically heterogeneous CFA adhesins are expected to protect against ETEC diarrhea. In this study, we created a CFA multiepitope fusion antigen (MEFA) carrying representative epitopes of CFA/I, CFA/II (CS1, CS2, and CS3), and CFA/IV (CS4, CS5, and CS6), examined its immunogenicity in mice, and assessed the potential of this MEFA as an antiadhesin vaccine against ETEC. Mice intraperitoneally immunized with this CFA MEFA exhibited no adverse effects and developed immune responses to CFA/I, CFA/II, and CFA/IV adhesins. Moreover, after incubation with serum of the immunized mice, ETEC or E. coli strains expressing CFA/I, CFA/II, or CFA/IV adhesins were significantly inhibited in adherence to Caco-2 cells. Our results indicated this CFA MEFA elicited antibodies that not only cross-reacted to CFA/I, CFA/II and CFA/IV adhesins but also broadly inhibited adherence of E. coli strains expressing these seven adhesins and suggested that this CFA MEFA could be a candidate to induce broad-spectrum antiadhesin protection against ETEC diarrhea. Additionally, this antigen construction approach (creating an MEFA) may be generally used in vaccine development against heterogenic pathogens.

Basic elements of logistics. Support for the cooperatives

Directory of Open Access Journals (Sweden)

Hilda Rosa Alvarez Puentes

2014-12-01

Full Text Available The logistical focus is constituting a demand of the current environment and conforming a new factor of competitive diferentiation, it is needed to develop it observing the due integration and the necessities of the organization in each moment. To accept this challenge it becomes necessary a development of the logistics in the organizations or cooperative at level of their philosophy, the structure, the concepts and the techniques.    The Logistics, as strategic tool of administration, is more and more grateful at international level, due to the high competitiveness that exists at the moment in all the sectors, and to the globalization of the markets.    The necessities of elementary knowledge of logistics for the best support in the new cooperatives on inherent basic aspects to this discipline, it will allow to appear the necessities and more urgent weaknesses that facilitate to endow certain presidents or associates, interested of basic knowledge for the sake of assuring their entities with supports keys for a sure and prosperous administration, relative to the essential topics of the logistics.

Integrated planning aimed at sustainability city logistics solutions

Directory of Open Access Journals (Sweden)

Tadić Snežana R.

2015-01-01

Full Text Available The main objective of city logistics system is sustainability, or efficiency, wide acceptability, environmental protection and safety. On the other hand, the city logistics system is very complex. It is characterized by a large number of participants, with different, usually conflicting goals and complex interactions. In addition, the system of city logistics is part of a wider system of the town, the region, and there are complex interactions with the external environment. The system depends on the specific characteristics of the city, affects other forms of urban mobility and is subject to the policies of higher rank (regional, national policy. Given the exceptional complexity, sustainable city logistics solution requires an integrated approach in all phases of planning, from stages of problem identification, definition of alternative solutions and effects assessment, to implementation and by exploitation. In this way, the solution of city logistics is becoming widely accepted and not only affects the efficiency of the socio-economic system of town, already on the sustainability of the whole region.

Impacts of infrastructure investment on logistics and transport

DEFF Research Database (Denmark)

Hansen, Leif Gjesing

2005-01-01

The article investigates the impacts of major traffic infrastructures on firms' organisation of logistics and transport.......The article investigates the impacts of major traffic infrastructures on firms' organisation of logistics and transport....

How is the DoD Logistics Transformation Going?

National Research Council Canada - National Science Library

Eden, Rick

2001-01-01

...: Cost Reduction--The DoD logistics system must reduce the costs of providing support. Responsiveness--The DoD logistics system must improve its basic business processes to match best commercial performance levels...

8th Workshop on Logistics and Supply Chain Management

CERN Document Server

Kaminsky, Phil; Müller, Thomas

2015-01-01

This contributed volume presents selected research papers from the 8th workshop on Logistics and Supply Chain Management, which was held in October 2013 in Berkeley, California. It focuses on the topical issue of quantitative approaches in logistics and supply chain management, mainly covering facility location and location routing; vehicle routing and scheduling; courier, express and parcel service network design; healthcare logistics as well as logistics risk management. The target audience primarily comprises research experts and practitioners in the field, but the book will also be beneficial to graduate students.

Relations between decision indicators for implementing technology in healthcare logistics – a bed logistics case study

DEFF Research Database (Denmark)

Feibert, Diana Cordes; Jacobsen, Peter

2015-01-01

The cost of healthcare is rising and reforms have been introduced across Europe to address the cost issue in healthcare. There is potential to improve logistical processes within healthcare to save costs and at the same time provide services that support high quality patient care. Re......-designing processes and implementing technology can improve the efficiency of processes and reduce costs. A relations diagram has been developed that identifies the effects between the constructs Logistics, Technology, Procedure and Structure. Knowledge about how these constructs affect each other is important when...

Cooperation and consolidation of flows in city logistics

Directory of Open Access Journals (Sweden)

Tadić Snežana R.

2015-01-01

Full Text Available Urban logistics systems are intensively changing and adapting to the demands of efficient supply and environmental protection. The productivity and profitability of companies and satisfaction of the resident's requirements in terms of the availability of various goods at lower prices, depends on the efficiency of the urban logistics system. On the other side, the level of interest in the environment is growing and initiates researches and implementation of effective and sustainable initiatives, city logistics concepts. The most frequently applied initiatives are those that relate to the regulation or restrictions and control of access for the urban freight vehicles. However, these initiatives don't solve the problems of commodity flows and can worsen logistics performance. Furthermore, they have not proved effective in terms of the environment and economy. For this reason, the concepts that involve the cooperation of carriers and consolidation of flows are promoted. They are focused on logistics activities and can provide many positive effects for the purpose of environmental and economic sustainability. Nevertheless, they are rarely implemented in practice, and most were scarcely successful. Mentioned facts indicate the importance of research of these conceptions, both from the aspect of the structure and characteristics of the logistics system, and the aspect of the role and functions of the public sector in their promotion.

Situational Awareness and Logistics Division

Data.gov (United States)

Federal Laboratory Consortium — Volpe's Situational Awareness and Logistics Division researches, develops, implements, and analyzes advanced systems to protect, enhance, and ensure resilienceof the...

The logistic model-generated carrying capacities, maximum ...

African Journals Online (AJOL)

This paper deals with the derivation of logistic models for cattle, sheep and goats in a commercial ranching system in Machakos District, Kenya, a savannah ecosystem with average annual rainfall of 589.3 ± 159.3mm and an area of 10 117ha. It involves modelling livestock population dynamics as discrete-time logistic ...

Perceived safety management practices in the logistics sector.

Science.gov (United States)

Auyong, Hui-Nee; Zailani, Suhaiza; Surienty, Lilis

2016-03-09

Malaysia's progress on logistics has been slowed to keep pace with its growth in trade. The Government has been pressing companies to improve the safety of their activities in order to reduce society's loss due to occupational accidents and illnesses. Occupational safety and health is a crucial part of a workplace because every worker has to take care of his/her own safety and health. The main occupational safety and health (OSH) national policy in Malaysia is the enactment of the Occupational Safety and Health Act (OSHA) 1994. Only those companies which have excellent health and safety care have good quality and productive employees. This study investigated safety management practices in the logistics sector. The present study is concerned with the human factors to safety in the logistics industry. The authors examined the perceived safety management practices of workers in the logistics sector. The purpose was to identify the perception of safety management practices of Malaysian logistics personnel. Survey questionnaires were distributed to assess logistics personnel about management commitment. The quantitative method using the availability sampling method was applied. The data gathered from the survey were analysed using SPSS software. The responses to the survey were rated according to the Likert scale type, with '1' indicating strongly disagree and '5' indicating strongly agree. One hundred and three employees of logistics functions completed the survey. The highest mean scores were found for fire apparatus, prioritisation of safety, and safety policy. The results from this study also emphasise the importance of the management's commitment in enhancing workplace safety. Specifically, companies should maintain good relations between the employer and the employee to help reduce workplace injuries.

Performance evaluation on aquatic product cold-chain logistics

Directory of Open Access Journals (Sweden)

Wenbing Wu

2015-11-01

Full Text Available Purpose: The requirements for high quality and diversification aquatic products are increasing with the improvement of Chinese living standard. However, the distribution between place of production and place of consumption are uneven, which results in large cold-chain logistics demand for aquatic products. At present, the low-level development of cold chain logistics has a bad impact on the circulation of aquatic products in China. So it is very urgent to develop cold-chain logistics in China. Design/methodology/approach: In order to do this, we apply performance evaluation, a well-known management tool, to study Chinese aquatic product cold-chain logistics. In this paper we first propose SISP(Subjects, Indexes, Standards, and Phases of performance evaluation model and ACSSN model(Aquatic product, Customer, Supply Chain, Society, and Node enterprises of supply chain for aquatic products cold-chain logistics performance evaluation. Then an ANP-Fuzzy method is proposed to evaluate the operational performance of Shandong Oriental Ocean Sci-Tech Co., Ltd. Furthermore, a system dynamic model is built to simulate the impact of temperature on the profits in aquatic products cold-chain sales section. Findings: We find out within a reasonable temperature range, lower temperature brings higher profit level. Also, performance improvement methods are proposed and the simulation of performance evaluation system is developed. Practical implications: Our findings can help to improve the level of aquatic product cold-chain logistics in China. Originality/value: The paper proposes the SISP (Subjects, Indexes, Standards, and Phases of performance evaluation model and ACSSN model (Aquatic product, Customer, Supply Chain, Society, and Node enterprises of supply chain for aquatic products cold-chain logistics performance evaluation.

Risk assessment of logistics outsourcing based on BP neural network

Science.gov (United States)

Liu, Xiaofeng; Tian, Zi-you

The purpose of this article is to evaluate the risk of the enterprises logistics outsourcing. To get this goal, the paper first analysed he main risks existing in the logistics outsourcing, and then set up a risk evaluation index system of the logistics outsourcing; second applied BP neural network into the logistics outsourcing risk evaluation and used MATLAB to the simulation. It proved that the network error is small and has strong practicability. And this method can be used by enterprises to evaluate the risks of logistics outsourcing.

Planning model of purchasing logistics in outsourcing

Directory of Open Access Journals (Sweden)

Igor JAKOMIN

2014-03-01

Full Text Available It is often the case that when preparing their offers, potential outsourcers of logistic activities do not thoroughly research all the activities that have an influence on the process of logistics. Consequently, they prepare relatively expensive offers (that can later lead to greater unexpected costs which, in many cases, business partners decide against and persist with their own existing methods of doing business. The original contribution to science in this article is a model that will aid better understanding of dealing with problems and will, in practice, serve as a tool for the successful execution of business offers by outsourcers. Following research we have discovered, and are able to confirm, that despite the high start-up costs of the outsourcing, in the long term the company can reduce logistic costs. The model presented serves as an in-depth analysis of the company which enables the definition of favourable and optimal offers for outsourcing. The model shown helps to minimise the influence of mistrust and emphasises the importance of reducing the logistic costs with outsourcing.

The Effects of Logistics Leverage in Marketing Systems

OpenAIRE

G.N. Okeudo

2012-01-01

An effective logistics system when incorporated into marketing can strengthen its operations and further give the firm a competitive edge. To design a marketing system which must maintain its market share, a firm must consider the effects of logistics and how its integration into marketing can produce several points of leverage. It is the purpose of this paper to highlight the leverage points available in any logistics units and to further analyze how marketing managers can work in sync with ...

Logistics: Price Rises Incurred by High Oil Price

Institute of Scientific and Technical Information of China (English)

Lai Zhihui

2011-01-01

@@ "When the oil price grows by 100%, the logistic indus-try will see a price growth of 40%, while the logistics in-dustry a price rise of 35%, which means every price increase of 5% in the oil price will bring along that of 2% in this industry." said Liu Zongsheng, General Manager of Itochu Logistics Co., Ltd., on the seminar "Focusing on the eco-nomic consequences of raising oil price, interest rate and deposit reserve ratio", which was held recently.

An integrated operation mode for green logistics of enterprises

Institute of Scientific and Technical Information of China (English)

Yu Chengxue; Wu Chunyou; Fan Yu

2006-01-01

The integrated operation mode of green logistics is a new enterprise's logistics operation and management mode concerning environment issues based on the traditional integrated mode. Through comparative study on the integrated operation mode of logistics based on self-operation, the operation mode of an integrated logistics of enterprises based on TPL, the green-supply chain management, and the operation mode of eco-industrial park (EIP), a relatively complete objective system structure is put forward for the integrated operation mode of green logistics of enterprises. Furthermore, the correspondent practical mode is also set up to help enterprises, especially for the manufacturing companies, not only improve the environment effectively, but support the technological framework for the enterprise's economic performance and social benefits in order to realize economic, social and environmental benefits are concerned.

Impact of Different Carbon Policies on City Logistics Network

Directory of Open Access Journals (Sweden)

Yang Jianhua

2015-01-01

Full Text Available A programming model for a four-layer urban logistics distribution network is constructed and revised based on three types of carbon emissions policies such as Carbon tax, carbon emissions Cap, Carbon Trade. Effects of different policies on logistics costs and carbon emissions are analyzed based on a spatial Logistics Infrastructure layout of Beijing. Research findings are as follows: First, based on low-carbon policies, the logistics costs and carbon emissions can be changed by different modes of transport in a certain extent; second, only when carbon taxes and carbon trading prices are higher, carbon taxes and carbon trading policies can reduce carbon emissions while not significantly increase logistics costs at the same time, and more effectively achieve carbon reduction targets than use carbon cap policy.

Activity-based Management of Logistic Costs in a Manufacturing Company: A Case of Increased Visibility of Logistics Costs in a Slovenian Paper Manufacturing Company

Directory of Open Access Journals (Sweden)

Julijana Krajnc

2012-01-01

Full Text Available Both the transparent reporting of logistics costs and the related accounting of their cost drivers present a significant factor for the successful management of material flows and the related logistics activities in production companies. These costs, which are mainly reported as part of overhead (indirect costs in such companies, usually remain hidden or are not explicitly visible when the traditional method of accounting is applied. The aim of this research is to create a model of activity-based accounting of logistics costs in a production company, and to test its efficiency in the disclosure of logistics costs compared with traditional cost accounting. The application of the model in a production company shows that an activity-based approach discloses as much as 108% more logistics costs at the level of a group of products than the traditional cost-accounting approach. Further, detailed information on logistics costs obtained in this way enables their more efficient management. Key words: logistics costs; activity-based costing; cost allocation; cost visibility; cost management

Nordic research in logistics and supply chain management

DEFF Research Database (Denmark)

Arlbjørn, Jan Stentoft; Jonsson, Patrik; Johansen, John

2006-01-01

management and to explain how the discipline differs in terms of demographics, research areas, methodological approach, resources and publication. The analysis is conducted in a Nordic research context through a survey distributed to persons with research interest in logistics and supply chain management......This article reflects on research completed within logistics and supply chain management in the Nordic countries based on an empirical analysis. The purpose of this paper is to describe the characteristics of the Nordic academic discipline working in the field of logistics and supply chain....... The research does not provide clear empirical evidence of the contours of a Nordic research paradigm within logistics and supply chain management. The analysis shows that the significant and typical research issues among the Nordic researchers are the focus on supply chains/networks as the most important...

Visualizing the Logistic Map with a Microcontroller

Science.gov (United States)

Serna, Juan D.; Joshi, Amitabh

2012-01-01

The logistic map is one of the simplest nonlinear dynamical systems that clearly exhibits the route to chaos. In this paper, we explore the evolution of the logistic map using an open-source microcontroller connected to an array of light-emitting diodes (LEDs). We divide the one-dimensional domain interval [0,1] into ten equal parts, an associate…

Analysis of Logistics in Support of a Human Lunar Outpost

Science.gov (United States)

Cirillo, William; Earle, Kevin; Goodliff, Kandyce; Reeves, j. D.; Andrashko, Mark; Merrill, R. Gabe; Stromgren, Chel

2008-01-01

Strategic level analysis of the integrated behavior of lunar transportation system and lunar surface system architecture options is performed to inform NASA Constellation Program senior management on the benefit, viability, affordability, and robustness of system design choices. This paper presents an overview of the approach used to perform the campaign (strategic) analysis, with an emphasis on the logistics modeling and the impacts of logistics resupply on campaign behavior. An overview of deterministic and probabilistic analysis approaches is provided, with a discussion of the importance of each approach to understanding the integrated system behavior. The logistics required to support lunar surface habitation are analyzed from both 'macro-logistics' and 'micro-logistics' perspectives, where macro-logistics focuses on the delivery of goods to a destination and micro-logistics focuses on local handling of re-supply goods at a destination. An example campaign is provided to tie the theories of campaign analysis to results generation capabilities.

and Multinomial Logistic Regression

African Journals Online (AJOL)

This work presented the results of an experimental comparison of two models: Multinomial Logistic Regression (MLR) and Artificial Neural Network (ANN) for classifying students based on their academic performance. The predictive accuracy for each model was measured by their average Classification Correct Rate (CCR).

Who controls the logistics emissions? Challenges in making fragmented supply chains environmentally sustainable from logistics service providers’ perspective

DEFF Research Database (Denmark)

Abbasi, Maisam; Sternberg, Henrik; Nilsson, Fredrik

2014-01-01

that impact the cost and time requirements from customers of logistics services are not yet a reality. Research limitations/implications (if applicable) This paper implies that LSP sustainability cannot be investigated in isolation if a company does not manage proprietary resources. Practical implications (if......Purpose The purpose of this article is to explore the environmental impact of Logistics Service Provider (LSP) activities in the light of increased customer attention and fragmentation of the industry. It also explores to what extent the LSPs can actually monitor the environmental impact...... of logistics activities in the supply chain? Design/methodology/approach The methodology of this paper is a literature review, a qualitative interview survey, and three case studies. A framework on sustainability challenges in supply chains derived from the literature is used to structure and analyze...

SPD-based Logistics Management Model of Medical Consumables in Hospitals

Science.gov (United States)

LIU, Tongzhu; SHEN, Aizong; HU, Xiaojian; TONG, Guixian; GU, Wei; YANG, Shanlin

2016-01-01

Background: With the rapid development of health services, the progress of medical science and technology, and the improvement of materials research, the consumption of medical consumables (MCs) in medical activities has increased in recent years. However, owing to the lack of effective management methods and the complexity of MCs, there are several management problems including MC waste, low management efficiency, high management difficulty, and frequent medical accidents. Therefore, there is urgent need for an effective logistics management model to handle these problems and challenges in hospitals. Methods: We reviewed books and scientific literature (by searching the articles published from 2010 to 2015 in Engineering Village database) to understand supply chain related theories and methods and performed field investigations in hospitals across many cities to determine the actual state of MC logistics management of hospitals in China. Results: We describe the definition, physical model, construction, and logistics operation processes of the supply, processing, and distribution (SPD) of MC logistics because of the traditional SPD model. With the establishment of a supply-procurement platform and a logistics lean management system, we applied the model to the MC logistics management of Anhui Provincial Hospital with good effects. Conclusion: The SPD model plays a critical role in optimizing the logistics procedures of MCs, improving the management efficiency of logistics, and reducing the costs of logistics of hospitals in China. PMID:27957435

SPD-based Logistics Management Model of Medical Consumables in Hospitals.

Science.gov (United States)

Liu, Tongzhu; Shen, Aizong; Hu, Xiaojian; Tong, Guixian; Gu, Wei; Yang, Shanlin

2016-10-01

With the rapid development of health services, the progress of medical science and technology, and the improvement of materials research, the consumption of medical consumables (MCs) in medical activities has increased in recent years. However, owing to the lack of effective management methods and the complexity of MCs, there are several management problems including MC waste, low management efficiency, high management difficulty, and frequent medical accidents. Therefore, there is urgent need for an effective logistics management model to handle these problems and challenges in hospitals. We reviewed books and scientific literature (by searching the articles published from 2010 to 2015 in Engineering Village database) to understand supply chain related theories and methods and performed field investigations in hospitals across many cities to determine the actual state of MC logistics management of hospitals in China. We describe the definition, physical model, construction, and logistics operation processes of the supply, processing, and distribution (SPD) of MC logistics because of the traditional SPD model. With the establishment of a supply-procurement platform and a logistics lean management system, we applied the model to the MC logistics management of Anhui Provincial Hospital with good effects. The SPD model plays a critical role in optimizing the logistics procedures of MCs, improving the management efficiency of logistics, and reducing the costs of logistics of hospitals in China.

Urban Logistics in Master Plan and a Review on Istanbul Master Plan

OpenAIRE

Senay Oguztimur; Metin Canci

2011-01-01

Urban logistics might be called as city logistics, urban freight transportation is a specific subsection of logistics concept. Urban logistics is generally based on logistics and freight activities in urban areas and focus on these activities' linkage with urban areas. Urban logistics issues might be evaluated under seven subtitles: These are respectively: logistics activities regarding with citizen subsistence, energy supply, industrial manufacturing, construction-maintenance activities, par...

Capturing Real-Time Data in Disaster Response Logistics

Directory of Open Access Journals (Sweden)

Kezban Yagci Sokat

2016-06-01

Full Text Available The volume, accuracy, accessibility and level of detail of near real-time data emerging from disaster-affected regions continue to significantly improve. Integration of dynamically evolving in-field data is an important, yet often overlooked, component of the humanitarian logistics models. In this paper, we present a framework for real-time humanitarian logistics data focused on use in mathematical modeling along with modeling implications of this framework. We also discuss how one might measure the attributes of the framework and describe the application of the presented framework to a case study of near real-time data collection in the days following the landfall of Typhoon Haiyan. We detail our first-hand experience of capturing data as the post-disaster response unfolds starting on November 10, 2013 until March 31, 2014 and assess the characteristics and evolution of data pertaining to humanitarian logistics modeling using the proposed framework. The presented logistical content analysis examines the availability of data and informs modelers about the current state of near real-time data. This analysis illustrates what data is available, how early it is available, and how data changes after the disaster. The study describes how our humanitarian logistics team approached the emergence of dynamic online data after the disaster and the challenges faced during the collection process, as well as recommendations to address these challenges in the future (when possible from an academic humanitarian logistics perspective.

Logistics Outsourcing and The Role of Logistics Service Providers: A Study About Steel Pipe Production Enterprises in Turkey

OpenAIRE

Yıldız, Mehmet Selami; Turan, İlker

2015-01-01

Specialization requirement led the outsourcing preferred intensely by firms. Evidently “logistics activities” constitute an important part in the outsourced business activities. In this study, interviews were conducted with the managers from Turkey's steel pipe production enterprises who have knowledge of logistics management. Fourteen steel pipe enterprises were included in the study. The collected data were analyzed by using quantitative methods and data were obtained by interview and face-...

Bifurcation and Fractal of the Coupled Logistic Map

Science.gov (United States)

Wang, Xingyuan; Luo, Chao

The nature of the fixed points of the coupled Logistic map is researched, and the boundary equation of the first bifurcation of the coupled Logistic map in the parameter space is given out. Using the quantitative criterion and rule of system chaos, i.e., phase graph, bifurcation graph, power spectra, the computation of the fractal dimension, and the Lyapunov exponent, the paper reveals the general characteristics of the coupled Logistic map transforming from regularity to chaos, the following conclusions are shown: (1) chaotic patterns of the coupled Logistic map may emerge out of double-periodic bifurcation and Hopf bifurcation, respectively; (2) during the process of double-period bifurcation, the system exhibits self-similarity and scale transform invariability in both the parameter space and the phase space. From the research of the attraction basin and Mandelbrot-Julia set of the coupled Logistic map, the following conclusions are indicated: (1) the boundary between periodic and quasiperiodic regions is fractal, and that indicates the impossibility to predict the moving result of the points in the phase plane; (2) the structures of the Mandelbrot-Julia sets are determined by the control parameters, and their boundaries have the fractal characteristic.

Cradle-to-Grave Logistic Technologies for Exploration Missions

Science.gov (United States)

Broyan, James L.; Ewert, Michael K.; Shull, Sarah

2013-01-01

Human exploration missions under study are very limited by the launch mass capacity of exiting and planned vehicles. The logistical mass of crew items is typically considered separate from the vehicle structure, habitat outfitting, and life support systems. Consequently, crew item logistical mass is typically competing with vehicle systems for mass allocation. NASA is Advanced Exploration Systems (AES) Logistics Reduction and Repurposing (LRR) Project is developing four logistics technologies guided by a systems engineering cradle-to-grave approach to enable used crew items to augment vehicle systems. Specifically, AES LRR is investigating the direct reduction of clothing mass, the repurposing of logistical packaging, the processing of spent crew items to benefit radiation shielding and water recovery, and the conversion of trash to propulsion supply gases. The systematic implementation of these types of technologies will increase launch mass efficiency by enabling items to be used for secondary purposes and improve the habitability of the vehicle as the mission duration increases. This paper provides a description, benefits, and challenges of the four technologies under development and a status of progress at the mid ]point of the three year AES project.

Bayesian logistic regression analysis

NARCIS (Netherlands)

Van Erp, H.R.N.; Van Gelder, P.H.A.J.M.

2012-01-01

In this paper we present a Bayesian logistic regression analysis. It is found that if one wishes to derive the posterior distribution of the probability of some event, then, together with the traditional Bayes Theorem and the integrating out of nuissance parameters, the Jacobian transformation is an

THE MAIN PROBLEMS OF DEVELOPMENT OF LOGISTIC CENTERS IN RUSSIAN REGIONS

Directory of Open Access Journals (Sweden)

Sergey Kalenteev

2012-01-01

Full Text Available The article covers the problem of the formation of modern logistics centers in Russia: the absence of a common interpretation of the term "logistics center", the lack of legislative frameworks formation and operation of logistics infrastructure, the underestimation of the social significance of logistics centers. There are suggestions to set of measures to remove barriers to service quality logistics services in the article.

Operation Mode and Optimum Design of China's Agricultural Modern Logistics System

OpenAIRE

Qin, Shi-bo

2012-01-01

Using comparative analysis and logical reasoning methods, in combination with traditional logistics theory and practice, and on the basis of objective demand of modern agricultural development for logistics service, we analyze features of logistics function. Besides, we discuss functional elements and service contents of agricultural modern logistics. In addition, we explore innovation model of agricultural modern logistics and systematized operation of supply chain. Finally, it is concluded ...

Relationship Marketing Researches in Logistics' Organizations: Foreign Countries Experience

OpenAIRE

Juščius, Vytautas; Grigaitė, Viktorija

2009-01-01

This paper presents the analysis of foreign researchers' works which scrutinize relationship marketing, its principles' adjustment in logistics organizations. Relationship marketing elements identified by different researchers, their influence and importance in relationship with clients in logistics organizations, relationship marketing implementation in business-to-business level are analyzed and compared. It leads to the conclusion that in logistics organizations relationship marketing elem...

[Appliancation of logistics in resources management of medical asset].

Science.gov (United States)

Miroshnichenko, Iu V; Goriachev, A B; Bunin, S A

2011-06-01

The usage of basic regulations of logistics in practical activity for providing joints and military units with medical asset is theoretically justified. The role of logistics in organizing, building and functioning of military (armed forces) medical supply system is found out. The methods of solving urgent problems of improvement the resources management of medical asset on the basis of logistics are presented.

Logistics Reduction: Heat Melt Compactor

Data.gov (United States)

National Aeronautics and Space Administration — The Advanced Exploration Systems (AES) Logistics Reduction (LR) project Heat Melt Compactor (HMC) technology is a waste management technology. Currently, there are...

IMPROVING HOSPITAL LOGISTICS BY RETHINKING TECHNOLOGY ASSESSMENT

DEFF Research Database (Denmark)

Jacobsen, Peter; Jørgensen, Pelle Morten Thomas

2011-01-01

In order to cope with the future challenges of the health care sector, there is an urging need for improving efficiency at hospitals. The study presents a framework enabling health care managers of improving the in-house logistics. The distinctiveness of the framework is the way in which it relates...... technology, logistics, structure and procedures to efficiency. Changing one factor e.g. technology, initiates an iterative loop focusing on change in the related factors in order to obtain the optimal efficiency. The search for an optimal efficient solution is the driving force of the framework...... at a Danish hospital. The framework is tested on the blood sample logistics between the emergency department and laboratory with the goal of enhancing the efficiency of the emergency department....

Logistic chaotic maps for binary numbers generations

International Nuclear Information System (INIS)

Kanso, Ali; Smaoui, Nejib

2009-01-01

Two pseudorandom binary sequence generators, based on logistic chaotic maps intended for stream cipher applications, are proposed. The first is based on a single one-dimensional logistic map which exhibits random, noise-like properties at given certain parameter values, and the second is based on a combination of two logistic maps. The encryption step proposed in both algorithms consists of a simple bitwise XOR operation of the plaintext binary sequence with the keystream binary sequence to produce the ciphertext binary sequence. A threshold function is applied to convert the floating-point iterates into binary form. Experimental results show that the produced sequences possess high linear complexity and very good statistical properties. The systems are put forward for security evaluation by the cryptographic committees.

Logistics case study based research: Towards higher quality

DEFF Research Database (Denmark)

Pedrosa, Alex; Näslund, Dag; Jasmand, Claudia

2012-01-01

analysis of 134 case study based articles published in six leading logistics and supply chain management (SCM) journals between 1998 and 2010 is used to assess and evaluate the quality of the case study based research approach as documented in these publications. Findings – This research provides...... to address to ensure high quality of the case study based research approach in published articles. Research limitations/implications – This study is limited to the analysis of published articles in six logistics and SCM journals. Further research should investigate different journals in logistics and other...

Analysis of the South African fruit logistics infrastructure

CSIR Research Space (South Africa)

Van Dyk, FE

2004-10-01

Full Text Available This paper gives an overview of a study that was done on the logistics infrastructure used by the South African fruit industry. Given the increasing production and export volumes, development of new markets and the shortage of logistics...

An allometric scaling relation based on logistic growth of cities

Science.gov (United States)

Chen, Yanguang

2014-08-01

The relationships between urban area and population size have been empirically demonstrated to follow the scaling law of allometric growth. This allometric scaling is based on exponential growth of city size and can be termed "exponential allometry", which is associated with the concepts of fractals. However, both city population and urban area comply with the course of logistic growth rather than exponential growth. In this paper, I will present a new allometric scaling based on logistic growth to solve the abovementioned problem. The logistic growth is a process of replacement dynamics. Defining a pair of replacement quotients as new measurements, which are functions of urban area and population, we can derive an allometric scaling relation from the logistic processes of urban growth, which can be termed "logistic allometry". The exponential allometric relation between urban area and population is the approximate expression of the logistic allometric equation when the city size is not large enough. The proper range of the allometric scaling exponent value is reconsidered through the logistic process. Then, a medium-sized city of Henan Province, China, is employed as an example to validate the new allometric relation. The logistic allometry is helpful for further understanding the fractal property and self-organized process of urban evolution in the right perspective.

Logistics Reduction and Repurposing Project

Data.gov (United States)

National Aeronautics and Space Administration — The project enables a largely mission-independent, cradle-to-grave-to-cradle approach to minimize logistics contributions to total mission architecture mass. The...

Formation and development of theoretical principles for mineral resources logistics

Directory of Open Access Journals (Sweden)

Б. К. Плоткин

2017-03-01

Full Text Available Market transformations in Russia became foundations for formation and development of a new scientific and practical field in economics – logistics. Out of more than 30 existing definitions of logistics the authors according to their opinion have chosen the most appropriate. Logistics of mineral resources should be attributed to production (industrial logistics. It is a proven fact that processes of supply chain management in mining industry and its infrastructure in the framework of mineral resources chain have some fundamental distinctions. Importance of material resources recycling in theory and practice of mineral resources logistics has been highlighted. Special features of merchandise assortment and classifications in the mining industry have been examined in conjunction with substantial contents of material flow. Special consideration has been given to relevant issues in the field of price formation for mining produce, in the view of specific relations between its costs and logistic procurement of the industry. Moreover, questions of inventory control in the mining industry, activity of commodity exchanges, management of mining logistics system have been addressed.

On interactions between Packaging and Logistics - Exploring implications of technological developments

OpenAIRE

Hellström, Daniel

2007-01-01

Packaging is a fundamental element in logistics systems. Packaging not only affects every logistical activity; it is also recognised as having a significant impact on logistics costs and performance. In order for logisticians and packaging professionals to gain insight into packaging-dependent costs and performance, the interactions between packaging systems and logistics systems must be understood. This is instead of dividing packaging and logistics into separate systems which are analysed o...

Viability analysis for use of hydrogen as fuel in logistics centers

OpenAIRE

Clemente Jul, María del Carmen; Fúnez Guerra, Carlos; Nieto Calderón, Beatriz; Jaén Caparros, María; Sendarrubias Carbonero, Vanessa; Reyes Bozo, Lorenzo; Godoy-faúndez, Álex; Vyhmeister, Eduardo

2017-01-01

The electricity cost in battery logistic center is cheaper (access to electricity grid with three period contract) that green hydrogen cost in hydrogen logistic center (hydrogen production plant, hydrogen transport and hydrogen refueling station in logistic center). The investment cost of hydrogen logistic center is cheaper (hydrogen forklift) than battery logistic center (battery forklift, second battery, battery charger and batteries area). The operation and maintenance cost for hydrogen lo...

Global trends and their impact on city logistics management

Directory of Open Access Journals (Sweden)

Tadić Snežana R.

2016-01-01

Full Text Available Changes in economic and social environments are more dynamic, and survival in the market requires a wide range, increase efficiency and quality of logistics services. The competitiveness of the region and the city, as the leader of economic development, depends on the efficiency of logistics solutions that must be adaptive to new conditions and demands of the market. This paper presents some of the most important global trends in terms of impact on the urban logistics. In order to define sustainable solutions, the analysis of presented social, economic, technological, environmental and other trends should be integral part of the city logistics planning and management.

Application of wireless sensor network technology in logistics information system

Science.gov (United States)

Xu, Tao; Gong, Lina; Zhang, Wei; Li, Xuhong; Wang, Xia; Pan, Wenwen

2017-04-01

This paper introduces the basic concepts of active RFID (WSN-ARFID) based on wireless sensor networks and analyzes the shortcomings of the existing RFID-based logistics monitoring system. Integrated wireless sensor network technology and the scrambling point of RFID technology. A new real-time logistics detection system based on WSN and RFID, a model of logistics system based on WSN-ARFID is proposed, and the feasibility of this technology applied to logistics field is analyzed.

Research and design of logistical information system based on SOA

Science.gov (United States)

Zhang, Bo

2013-03-01

Through the study on the existing logistics information systems and SOA technology, based on the current situation of enterprise logistics management and business features, this paper puts forward a SOA-based logistics system design program. This program is made in the WCF framework, with the combination of SOA and the actual characteristics of logistics enterprises, is simple to realize, easy to operate, and has strong expansion characteristic, therefore has high practical value.

Education, Training and the Role of Logistic Managers in Ireland

OpenAIRE

Mangan, John; Gregory, Orla

2001-01-01

The paper is based on the analysis of the responses of a questionnaire survey of logistics managers working in manufacturing firms in Ireland. The objectives of the survey were to establish the educational and training needs of the practicing logistics manager. The questionnaire was designed to address issues including the various logistics practices undertaken by the respondents' company and the time spent by respondents on these activities; the skills currently required by logistics manager...

Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization Factors

KAUST Repository

Joffré , Enrique; von Mentzer, Astrid; Abd El Ghany, Moataz; Oezguen, Numan; Savidge, Tor; Dougan, Gordon; Svennerholm, Ann-Mari; Sjö ling, Å sa

2015-01-01

Enterotoxigenic Escherichia coli (ETEC) is a significant cause of morbidity and mortality in the developing world. ETEC-mediated diarrhea is orchestrated by heat-labile toxin (LT) and heat-stable toxins (STp and STh), acting in concert with a repertoire of more than 25 colonization factors (CFs). LT, the major virulence factor, induces fluid secretion after delivery of a monomeric ADP-ribosylase (LTA) and its pentameric carrier B subunit (LTB). A study of ETEC isolates from humans in Brazil reported the existence of natural LT variants. In the present study, analysis of predicted amino acid sequences showed that the LT amino acid polymorphisms are associated with a geographically and temporally diverse set of 192 clinical ETEC strains and identified 12 novel LT variants. Twenty distinct LT amino acid variants were observed in the globally distributed strains, and phylogenetic analysis showed these to be associated with different CF profiles. Notably, the most prevalent LT1 allele variants were correlated with major ETEC lineages expressing CS1 + CS3 or CS2 + CS3, and the most prevalent LT2 allele variants were correlated with major ETEC lineages expressing CS5 + CS6 or CFA/I. LTB allele variants generally exhibited more-stringent amino acid sequence conservation (2 substitutions identified) than LTA allele variants (22 substitutions identified). The functional impact of LT1 and LT2 polymorphisms on virulence was investigated by measuring total-toxin production, secretion, and stability using GM1-enzyme-linked immunosorbent assays (GM1-ELISA) and in silico protein modeling. Our data show that LT2 strains produce 5-fold more toxin than LT1 strains (P < 0.001), which may suggest greater virulence potential for this genetic variant. Our data suggest that functionally distinct LT-CF variants with increased fitness have persisted during the evolution of ETEC and have spread globally.

Allele Variants of Enterotoxigenic Escherichia coli Heat-Labile Toxin Are Globally Transmitted and Associated with Colonization Factors

KAUST Repository

Joffré, Enrique

2015-01-15

Enterotoxigenic Escherichia coli (ETEC) is a significant cause of morbidity and mortality in the developing world. ETEC-mediated diarrhea is orchestrated by heat-labile toxin (LT) and heat-stable toxins (STp and STh), acting in concert with a repertoire of more than 25 colonization factors (CFs). LT, the major virulence factor, induces fluid secretion after delivery of a monomeric ADP-ribosylase (LTA) and its pentameric carrier B subunit (LTB). A study of ETEC isolates from humans in Brazil reported the existence of natural LT variants. In the present study, analysis of predicted amino acid sequences showed that the LT amino acid polymorphisms are associated with a geographically and temporally diverse set of 192 clinical ETEC strains and identified 12 novel LT variants. Twenty distinct LT amino acid variants were observed in the globally distributed strains, and phylogenetic analysis showed these to be associated with different CF profiles. Notably, the most prevalent LT1 allele variants were correlated with major ETEC lineages expressing CS1 + CS3 or CS2 + CS3, and the most prevalent LT2 allele variants were correlated with major ETEC lineages expressing CS5 + CS6 or CFA/I. LTB allele variants generally exhibited more-stringent amino acid sequence conservation (2 substitutions identified) than LTA allele variants (22 substitutions identified). The functional impact of LT1 and LT2 polymorphisms on virulence was investigated by measuring total-toxin production, secretion, and stability using GM1-enzyme-linked immunosorbent assays (GM1-ELISA) and in silico protein modeling. Our data show that LT2 strains produce 5-fold more toxin than LT1 strains (P < 0.001), which may suggest greater virulence potential for this genetic variant. Our data suggest that functionally distinct LT-CF variants with increased fitness have persisted during the evolution of ETEC and have spread globally.

A new experimental approach to study the stability of logistic map

International Nuclear Information System (INIS)

Rani, Mamta; Agarwal, Rashi

2009-01-01

Remarkably benign looking logistic transformations x n+1 = rx n (1 - x n ) for choosing x 0 between 0 and 1 and 0 < r ≤ 4 have found a celebrated place in chaos, fractals and discrete dynamics. The purpose of this paper is to enhance the capabilities of logistic map via superior iterations. Stability of logistic map has been studied by running computer programs. Logistic map is stable for 0 < r ≤ 3.2 in Picard orbit. In superior orbit, we see that the range of stability of logistic map increases drastically. Also, chaotic behavior of logistic map disappears in certain cases.

Logistics Outsourcing : Current state of the market of outsourcing logistics services

OpenAIRE

Odnokonnaya, Marina

2017-01-01

In this thesis the market of outsourcing logistics services was studied. The thesis is divided into three major parts. First part regards the outsourcing itself: types of outsourcing, reasons to outsource, activities that company may outsource, possible risks, consequences and decision-making process. The second part concerns providers: types of providers, parameters for choosing the right provider, the decision-making process in terms of choosing provider and management of relationships with...

NASA Advanced Explorations Systems: Concepts for Logistics to Living

Science.gov (United States)

Shull, Sarah A.; Howe, A. Scott; Flynn, Michael T.; Howard, Robert

2012-01-01

The NASA Advanced Exploration Systems (AES) Logistics Reduction and Repurposing (LRR) project strives to enable a largely mission-independent cradle-to-grave-to-cradle approach to minimize logistics contributions to total mission architecture mass. The goals are to engineer logistics materials, common crew consumables, and container configurations to meet the following five basic goals: 1. Minimize intrinsic logistics mass and improve ground logistics flexibility. 2. Allow logistics components to be directly repurposed for on-orbit non-logistics functions (e.g., crew cabin outfitting) thereby indirectly reducing mass/volume. 3. Compact and process logistics that have not been directly repurposed to generate useful on-orbit components and/or compounds (e.g., radiation shielding, propellant, other usable chemical constituents). 4. Enable long-term stable storage and disposal of logistics end products that cannot be reused or repurposed (e.g., compaction for volume reduction, odor control, and maintenance of crew cabin hygienic conditions). 5. Allow vehicles in different mission phases to share logistics resources. This paper addresses the work being done to meet the second goal, the direct repurposing of logistics components to meet other on-orbit needs, through a strategy termed Logistics to Living (L2L). L2L has several areas but can be defined as repurposing or converting logistical items (bags, containers, foam, components, etc.) into useful crew items or life support augmentation on-orbit after they have provided their primary logistics function. The intent is that by repurposing items, dedicated crew items do not have to be launched and overall launch mass is decreased. For non-LEO missions, the vehicle interior volume will be relatively fixed so L2L will enable this volume to be used more effectively through reuse and rearrangement of logistical components. Past work in the area of L2L has already conceptually developed several potential technologies [Howe

Logistics research report : Framework in the healthcare industry

NARCIS (Netherlands)

Willems, A.; Hajdasinski, A.K.; Willems, J.

2009-01-01

The research report takes the perspective of Information Logistics and investigates relating concepts like Knowledge Management, Information Systems and Context Awareness in the context of the healthcare industry. The aim of Information Logistics is to deliver the right information product, in the

ANIMAL ENTEROTOXIGENIC ESCHERICHIA COLI

Science.gov (United States)

Dubreuil, J. Daniel; Isaacson, Richard E.; Schifferli, Dieter M.

2016-01-01

Enterotoxigenic Escherichia coli (ETEC) is the most common cause of E. coli diarrhea in farm animals. ETEC are characterized by the ability to produce two types of virulence factors; adhesins that promote binding to specific enterocyte receptors for intestinal colonization and enterotoxins responsible for fluid secretion. The best-characterized adhesins are expressed in the context of fimbriae, such as the F4 (also designated K88), F5 (K99), F6 (987P), F17 and F18 fimbriae. Once established in the animal small intestine, ETEC produces enterotoxin(s) that lead to diarrhea. The enterotoxins belong to two major classes; heat-labile toxin that consist of one active and five binding subunits (LT), and heat-stable toxins that are small polypeptides (STa, STb, and EAST1). This chapter describes the disease and pathogenesis of animal ETEC, the corresponding virulence genes and protein products of these bacteria, their regulation and targets in animal hosts, as well as mechanisms of action. Furthermore, vaccines, inhibitors, probiotics and the identification of potential new targets identified by genomics are presented in the context of animal ETEC. PMID:27735786

Feed Fermentation with Reuteran- and Levan-Producing Lactobacillus reuteri Reduces Colonization of Weanling Pigs by Enterotoxigenic Escherichia coli.

Science.gov (United States)

Yang, Yan; Galle, Sandra; Le, Minh Hong Anh; Zijlstra, Ruurd T; Gänzle, Michael G

2015-09-01

This study determined the effect of feed fermentation with Lactobacillus reuteri on growth performance and the abundance of enterotoxigenic Escherichia coli (ETEC) in weanling piglets. L. reuteri strains produce reuteran or levan, exopolysaccharides that inhibit ETEC adhesion to the mucosa, and feed fermentation was conducted under conditions supporting exopolysaccharide formation and under conditions not supporting exopolysaccharide formation. Diets were chosen to assess the impact of organic acids and the impact of viable L. reuteri bacteria. Fecal samples were taken throughout 3 weeks of feeding; at the end of the 21-day feeding period, animals were euthanized to sample the gut digesta. The feed intake was reduced in pigs fed diets containing exopolysaccharides; however, feed efficiencies did not differ among the diets. Quantification of L. reuteri by quantitative PCR (qPCR) detected the two strains used for feed fermentation throughout the intestinal tract. Quantification of E. coli and ETEC virulence factors by qPCR demonstrated that fermented diets containing reuteran significantly (P reuteri reduced the level of colonization of weaning piglets with ETEC, and feed fermentation supplied concentrations of reuteran that may specifically contribute to the effect on ETEC. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Single Chain Variable Fragments Produced in Escherichia coli against Heat-Labile and Heat-Stable Toxins from Enterotoxigenic E. coli.

Directory of Open Access Journals (Sweden)

Christiane Y Ozaki

Full Text Available Diarrhea is a prevalent pathological condition frequently associated to the colonization of the small intestine by enterotoxigenic Escherichia coli (ETEC strains, known to be endemic in developing countries. These strains can produce two enterotoxins associated with the manifestation of clinical symptoms that can be used to detect these pathogens. Although several detection tests have been developed, minimally equipped laboratories are still in need of simple and cost-effective methods. With the aim to contribute to the development of such diagnostic approaches, we describe here two mouse hybridoma-derived single chain fragment variable (scFv that were produced in E. coli against enterotoxins of ETEC strains.Recombinant scFv were developed against ETEC heat-labile toxin (LT and heat-stable toxin (ST, from previously isolated hybridoma clones. This work reports their design, construction, molecular and functional characterization against LT and ST toxins. Both antibody fragments were able to recognize the cell-interacting toxins by immunofluorescence, the purified toxins by ELISA and also LT-, ST- and LT/ST-producing ETEC strains.The developed recombinant scFvs against LT and ST constitute promising starting point for simple and cost-effective ETEC diagnosis.

Overview of Low Carbon Logistics Development in China and Foreign Countries

Science.gov (United States)

Cheng, Dongxiang; Zhang, Xiang

2017-12-01

High energy consumption is a major feature of the logistics industry. Under the current low-carbon development requirements, the low carbon development of logistics is bound to be a new direction, and more scholars will turn their attention to low-carbon logistics. This paper presents a detailed introduction to low-carbon logistics from four aspects: the definition of low-carbon logistics, the influencing factors and Countermeasures of development, and the evaluation of carbon emission efficiency.

Diagnostical Procedure for Logistical Management in Turistical Entities

Directory of Open Access Journals (Sweden)

Libia Arlen Fergusson-Álvarez

2016-06-01

Full Text Available This research aims to design a diagnostic procedure of the logistics management for turistical entities, they could be hotels or not. This procedure was validated in Commercial Branch Caracol Santiago de Cuba and finally, different actions for the detected problems were proposed with the objective of improving the logistics management of the organization. To develop this research various tools and techniques served as support, such as: surveys, SPSS software (Statistical Package for Social Sciences 15.0 version and Decision 1.0 version, exponential smoothing, Cronbach's Alpha, the coefficient of Kendall W, financial and logistical indicators, the ABC or Pareto Method, the matrices for the classification of stocks and suppliers, among others. This research made possible the design of a diagnostic procedure for logistical management for turistical entities. And it was validated in the Comercial Branch Caracol Santiago, which allowed the proposition of improvement actions for increasing customer satisfaction.

Green Logistic Practices: A Theoretical Approach of the Theme

Directory of Open Access Journals (Sweden)

Emanuele Engelage

2016-12-01

Full Text Available This study aims to identify the main practices of green logistic considered in national and international academic literature. Using standard techniques for selection of previous studies, this study firts presents the definition of green logistic term in order to differentiate it from other concepts commonly treated similarly, as circular economy, the green chain management (GSCM, the reverse logistics and the environmental certifications (ISO 14001, to obtain clarity about their delimitations, scopes and depth. The study also organizes a taxonomy that involves different functional areas of the company, giving direction to the sustainable conduct, resulting in nine components of green logistic that serve as subsidy for the classification of the identified practices. Based on this conceptual definition and taxonomy, lists 112 practices of green logistic, among which 85 are enterprise ambit, 24 governmental and 3 towards consumers. Regarding the quantity of identified practices and the number of citations, both in business sphere as well as in governmental, the most representative part is related to green  Among the most cited practices are the search by more efficient deliveries, using intermodal and multimodal transport that are less polluting and the programming and optimization of flows deliveries. The survey also revealed that although the concept of green logistics is consolidated in the literature, the majority of studies, especially the empirical, concentrates on some of its components, in particular transport and reverse logistic.