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Sample records for estonian test reference

  1. Speech audiometry in Estonia: Estonian words in noise (EWIN) test.

    Science.gov (United States)

    Veispak, Anneli; Jansen, Sofie; Ghesquière, Pol; Wouters, Jan

    2015-08-01

    Currently, there is no up-to-date speech perception test available in the Estonian language that may be used to diagnose hearing loss and quantify speech intelligibility. Therefore, based on the example of the Nederlandse Vereniging voor Audiologie (NVA)-lists ( Bosman, 1989 ; Wouters et al, 1994 ) an Estonian words in noise (EWIN) test has been developed. Two experimental steps were carried out: (1) selection and perceptual optimization of the monosyllables, and (2) construction of 14 lists and an evaluation in normal hearing (NH) subjects both in noise and in quiet. Thirty-six normal-hearing (NH) native speakers of Estonia (age range from 17 to 46 years). The reference psychometric curve for NH subjects was determined, with the slope and speech reception threshold being well in accordance with the respective values of the NVA lists. The 14 lists in noise yielded equivalent scores with high precision. The EWIN test is a reliable and valid speech intelligibility test, and is the first of its kind in the Estonian language.

  2. Testing the Visual Soil Assessment tool on Estonian farm fields

    Science.gov (United States)

    Reintam, Endla; Are, Mihkel; Selge, Are

    2017-04-01

    Soil quality estimation plays important role in decision making on farm as well on policy level. Sustaining the production ability and good health of the soil the chemical, physical and biological indicators should be taken into account. The system to use soil chemical parameters is usually quite well established in most European counties, including Estonia. However, measuring soil physical properties, such bulk density, porosity, penetration resistance, structural stability ect is time consuming, needs special tools and is highly weather dependent. In that reason these parameters are excluded from controllable quality parameters in policy in Estonia. Within the project "Interactive Soil Quality Assessment in Europe and China for Agricultural Productivity and Environmental Resilience" (iSQAPER) the visual soil assessment (VSA) tool was developed for easy detection of soil quality as well the different soil friendly agricultural management practices (AMP) were detected. The aim of current study was to test the VSA tool on Estonian farm fields under different management practices and compare the results with laboratory measurements. The main focus was set on soil physical parameters. Next to the VSA, the undisturbed soil samples were collected from the depth of 5-10 cm and 25-30 cm. The study revealed that results of a visually assessed soil physical parameters, such a soil structure, soil structural stability, soil porosity, presence of tillage pan, were confirmed by laboratory measurements in most cases. Soil water stable structure measurement on field (on 1 cm2 net in one 1 l box with 4-6 cm air dry clods for 5-10 min) underestimated very well structured soil on grassland and overestimated the structure aggregates stability of compacted soil. The slightly better soil quality was detected under no-tillage compared to ploughed soils. However, the ploughed soil got higher quality points compared with minimum tillage. The slurry application (organic manuring) had

  3. HIV testing and counselling in Estonian prisons, 2012 to 2013: aims, processes and impacts.

    Science.gov (United States)

    Kivimets, K; Uuskula, A

    2014-11-27

    We present data from an observational cohort study on human immunodeficiency virus (HIV) prevention and control measures in prisons in Estonia to assess the potential for HIV transmission in this setting. HIV testing and retesting data from the Estonian prison health department were used to estimate HIV prevalence and incidence in prison. Since 2002, voluntary HIV counselling and testing has routinely been offered to all prisoners and has been part of the new prisoners health check. At the end of 2012, there were 3,289 prisoners in Estonia, including 170 women: 28.5% were drug users and 15.6% were infected with HIV. Of the HIV-positive inmates, 8.3% were newly diagnosed on prison entry. In 2012, 4,387 HIV tests (including retests) were performed in Estonian prisons. Among 1,756 initially HIV-negative prisoners who were in prison for more than one year and therefore tested for HIV twice within 12 months (at entry and annual testing), one new HIV infection was detected, an incidence of 0.067 per 100 person-years (95% confidence interval (CI): 0.025–5.572). This analysis indicates low risk of HIV transmission in Estonian prisons. Implementation of HIV management interventions could impact positively on the health of prisoners and the communities to which they return.

  4. Chromosomal microarray analysis as a first-tier clinical diagnostic test: Estonian experience.

    Science.gov (United States)

    Zilina, Olga; Teek, Rita; Tammur, Pille; Kuuse, Kati; Yakoreva, Maria; Vaidla, Eve; Mölter-Väär, Triin; Reimand, Tiia; Kurg, Ants; Ounap, Katrin

    2014-03-01

    Chromosomal microarray analysis (CMA) is now established as the first-tier cytogenetic diagnostic test for fast and accurate detection of chromosomal abnormalities in patients with developmental delay/intellectual disability (DD/ID), multiple congenital anomalies (MCA), and autism spectrum disorders (ASD). We present our experience with using CMA for postnatal and prenatal diagnosis in Estonian patients during 2009-2012. Since 2011, CMA is on the official service list of the Estonian Health Insurance Fund and is performed as the first-tier cytogenetic test for patients with DD/ID, MCA or ASD. A total of 1191 patients were analyzed, including postnatal (1072 [90%] patients and 59 [5%] family members) and prenatal referrals (60 [5%] fetuses). Abnormal results were reported in 298 (25%) patients, with a total of 351 findings (1-3 per individual): 147 (42%) deletions, 106 (30%) duplications, 89 (25%) long contiguous stretches of homozygosity (LCSH) events (>5 Mb), and nine (3%) aneuploidies. Of all findings, 143 (41%) were defined as pathogenic or likely pathogenic; for another 143 findings (41%), most of which were LCSH, the clinical significance remained unknown, while 61 (18%) reported findings can now be reclassified as benign or likely benign. Clinically relevant findings were detected in 126 (11%) patients. However, the proportion of variants of unknown clinical significance was quite high (41% of all findings). It seems that our ability to detect chromosomal abnormalities has far outpaced our ability to understand their role in disease. Thus, the interpretation of CMA findings remains a rather difficult task requiring a close collaboration between clinicians and cytogeneticists.

  5. Estonian literature / Janika Kronberg

    Index Scriptorium Estoniae

    Kronberg, Janika, 1963-

    2003-01-01

    Sisu: Estonian literature - born on the margins of Europe ; Baltic German literature and its impact ; Seeking the contours of a 'truly' Estonian literature ; Literature and an independent Estonia ; Estonian literature in two cultural spheres ; The fifties and sixties ; Literature and congealed time ; A bold new Estonian literature

  6. Online Estonian Language Learning

    Science.gov (United States)

    Teral, Maarika; Rammo, Sirje

    2014-01-01

    This presentation focuses on computer-assisted learning of Estonian, one of the lesser taught European languages belonging to the Finno-Ugric language family. Impulses for this paper came from Estonian courses that started in the University of Tartu in 2010, 2011 and 2012. In all the courses the students gain introductory knowledge of Estonian and…

  7. Selenium levels of Estonians.

    Science.gov (United States)

    Rauhamaa, P; Kantola, M; Viitak, A; Kaasik, T; Mussalo-Rauhamaa, H

    2008-09-01

    The objective of this study is to sum up the dietary selenium intake of the Estonian people according to the serum selenium concentrations. This research compiles the information published in the literature about the levels of selenium in the serum of the Estonian people. We compare these results with the findings obtained from the analyses of serum samples gathered by us in the 1990s in Estonia. The selenium concentration in sera of 404 Estonians ranged from 26 to 116 microg/l; the mean was 75 microg/l. The selenium contents of Estonians were at a similar level as reported for Finns before the selenium supplementation of fertilizers carried out in Finland in 1984. In view of the selenium concentration in the sera, we suggest that the dietary selenium intake among the Estonian people might be scarce, and Estonian authorities should consider in their nutrition policies the possible low intake of selenium of Estonians.

  8. Valued Estonian Music CDs

    Index Scriptorium Estoniae

    2004-01-01

    2002. aastal välja antud eesti muusika heliplaatidest Artur Kapp "Symphonische Werke", Eduard Tubin "Symphonies No.9, No.10 and No.11", "Estonian Preludes", "Eesti heliloojad. Hortus Musicus", "Eesti Muusika Päevad", "Tallinn Saxophone Quartet. Estonian Contemporary Music", "Triskele. Kolga-Jaani vaimulikud rahvalaulud", "Helmekaala. Linnupuu Anne", "Modern Fox mängib Raimond Valgret",

  9. INTRODUCTION TO ESTONIAN LINGUISTICS.

    Science.gov (United States)

    RAUN, ALO; SAARESTE, ANDRUS

    THIS TEXT COMPRISES A SURVEY OF THE ESTONIAN LANGUAGE, WHICH IS GROUPED HERE WITH LIVONIAN, VOTIC, AND A PART OF WESTERN FINNISH, TO FORM THE SOUTHWESTERN BRANCH OF THE FINNIC (OR BALTO-FINNIC) LANGUAGES. THE AUTHORS' CLASSIFICATIONS AND A HISTORY OF THE STUDIES WHICH HAVE BEEN CARRIED OUT IN ESTONIAN ARE PRESENTED, FOLLOWED BY A PRESENTATION OF…

  10. Clinical laboratory test reference (CLTR).

    Science.gov (United States)

    Grams, R R

    1993-04-01

    As the healthcare system undergoes a transformation in scope and funding, there remain many unfinished projects which will be essential for the next generation of automated medical support services. The most demanding and labor intensive tasks for this new frontier deal with the accumulation of knowledge which can be used as a clinical database to support supervisory functions in a physician operated interactive care delivery environment. These databases will contain the worlds accumulated knowledge in specialized areas. They will be organized by topic or clinical service, and have significant impact on the quality of care as well as medical malpractice exposure. This article will describe a clinical pathology database that has been adapted for medical practice. The database contains information about laboratory tests and their interpretation. The data is structured for rapid reading and has references where indicated. The database can be used in a stand alone program or integrated into an information system within an application program. The files are reviewed on a continuing basis and quarterly updates are made available to subscribers.

  11. ESTONIAN EDUCATION SYSTEM FEATURES

    National Research Council Canada - National Science Library

    Marcos Francisco Rodríguez Bravo

    2015-01-01

    This article attempts to identify structural elements of the Estonian education system which has obtained in the last PISA 2012 international report, some results well above the average set by the OECD (494...

  12. What Determines the Response: Test or Reference?

    Science.gov (United States)

    Chukova, S. V.; Ahumada, A. J., Jr.; Null, Cynthia (Technical Monitor)

    1998-01-01

    The stability of sensory memory has been studied by presenting a reference stimulus, a delay, and a test stimulus. As has been pointed out by Lages and Treisman (1998 Vision Research 38 557-572), the usual measure of performance depends only on the effect of test variations on the responses. The Weber fraction characterizing performance is more properly called the test stimulus Weber fraction. We measure the relative contribution of the test and reference to the response by the ratio of the test Weber fraction to the reference Weber fraction. The stimuli were two dark lines on a bright background. Seven reference separations, varying from 9.5 to 16.7 arc min, were intermixed in each run. Interstimulus intervals (ISI) of 50, 200 and 2000 msec and intertrial intervals (ITI) of 500 and 2500 msec were investigated. When the ISI was short (50 or 200 msec), for both ITIs, responses were determined equally by the test and reference. For the long ISI (2000 msec), the reference stimulus contributed less. However, only for the 500 msec ITI (and not for all observers) was the contribution of the reference stimulus negligible, as Treisman's criterion setting theory might suggest.

  13. Bibliography of Testing and Evaluation Reference Material

    Science.gov (United States)

    1989-08-01

    Operational Test and Evaluation Center (AFOTEC) Software Evaluation Manager (SEM) and Deputy for Software Evaluation ( DSE ). It describes the numerous...Army87] Overview: The Software Test and Evaluation Manual is a three volume reference set that provides checklists and guidance to Department of...test plan). The content definition of a standardized test * 271 August 9, 1989 document can serve as a completeness checklist for the associated

  14. Weather Test Reference Year of Greenland

    DEFF Research Database (Denmark)

    Kragh, Jesper; Pedersen, Frank; Svendsen, Svend

    2005-01-01

    The building code of Greenland from 1982 is to be revised in the coming years fulfilling the increased demand of more energy efficient buildings. To establish appropriate levels of energy consumption for heating the weather conditions have to be analyzed. The purpose of this paper is to describe...... test reference year is constructed using measurements from the town Uummannaq located in the north part of Greenland on the west coast. The construction of the test reference years fulfills the procedures described in the standard EN ISO 15927-4 using the following main weather parameters: Dry bulb...

  15. Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu.

    Science.gov (United States)

    Leitsalu, Liis; Haller, Toomas; Esko, Tõnu; Tammesoo, Mari-Liis; Alavere, Helene; Snieder, Harold; Perola, Markus; Ng, Pauline C; Mägi, Reedik; Milani, Lili; Fischer, Krista; Metspalu, Andres

    2015-08-01

    The Estonian Biobank cohort is a volunteer-based sample of the Estonian resident adult population (aged ≥18 years). The current number of participants-close to 52000--represents a large proportion, 5%, of the Estonian adult population, making it ideally suited to population-based studies. General practitioners (GPs) and medical personnel in the special recruitment offices have recruited participants throughout the country. At baseline, the GPs performed a standardized health examination of the participants, who also donated blood samples for DNA, white blood cells and plasma tests and filled out a 16-module questionnaire on health-related topics such as lifestyle, diet and clinical diagnoses described in WHO ICD-10. A significant part of the cohort has whole genome sequencing (100), genome-wide single nucleotide polymorphism (SNP) array data (20 000) and/or NMR metabolome data (11 000) available (http://www.geenivaramu.ee/for-scientists/data-release/). The data are continuously updated through periodical linking to national electronic databases and registries. A part of the cohort has been re-contacted for follow-up purposes and resampling, and targeted invitations are possible for specific purposes, for example people with a specific diagnosis. The Estonian Genome Center of the University of Tartu is actively collaborating with many universities, research institutes and consortia and encourages fellow scientists worldwide to co-initiate new academic or industrial joint projects with us. © The Author 2014; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

  16. Residues of persistent organic pollutants in Estonian soils

    Directory of Open Access Journals (Sweden)

    Kumar, Kurunthachalam Senthil

    2009-06-01

    Full Text Available Organochlorine pesticides (OCPs, polychlorinated biphenyls (PCBs, and polybrominated diphenyl ethers (PBDEs were analysed in selected Estonian soils. The sample collection included agricultural-rural (Ahja, Eerika, industrial-urban (Kohtla-Järve, Muuga, Kunda, and reference sites (Lahemaa and Vilsandi. The PCB concentrations were greater in Ahja-1982 and Kohtla-Järve station 1, while Eerika, other Kohtla-Järve, Muuga Port, Kunda, Lahemaa, and Vilsandi Island concentrations were low. Organochlorine pesticides were slightly higher at Kohtla-Järve stations and PBDEs at Kunda stations. Overall, the predominant contaminants were PCBs (0.43–89 ng/g dw, followed by OCPs (0.21–16 ng/g dw and PBDEs (< 0.01–3.2 ng/g dw. The occurrence of 4,4'-DDT in some samples indicated recent contamination by DDT of Estonian soils. The PBDEs in Estonian soils were reported for the first time.

  17. Estonian Airi uued soodsad pakkumised

    Index Scriptorium Estoniae

    2010-01-01

    Estonian Airi kodulehelt on võimalik osta lennupileteid koostööpartnerite poolt pakutavatele mandritevahelistele lendudele ning broneerida internetis hotellituba Euroopa suurima hotelli broneerimise teenust pakkuva ettevõtte Booking.com kaudu

  18. Estonian Air sai lennukilisa / Gert D. Hankewitz

    Index Scriptorium Estoniae

    Hankewitz, Gert D.

    2007-01-01

    Lennukompanii Estonian Air liisib kolm uut lennukit. Kommenteerib Rein Loik. Vt. samas intervjuud SAS-i asepresidendi Per Jensen Mölleriga, kes eitab spekulatsioone, et SAS võiks airBalticu ja Estonian Airi liita

  19. [Mati Erelt. Estonian Language] / Katrin Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Katrin

    2004-01-01

    Arvustus: Estonian language / [Estonian Academy of Sciences] ; edited by Mati Erelt.Tallinn : Teaduste Akadeemia Kirjastus, 2003. 412, [1] lk. : ill., kaart. (Linguistica Uralica. Supplementary series, 0868-4731 ; vol. 1)

  20. Unemployment hysteresis in the “Nordic Kitten”: Evidence from five Estonian regions

    OpenAIRE

    Furuoka Fumitaka

    2015-01-01

    Unemployment hysteresis is a much discussed and researched topic in macroeconomics. The present paper examined unemployment hysteresis in five Estonian regions. It used two panel data methods, namely, the Im-Pesaran-Shin (IPS) test and the Fourier Im-Pesaran-Shin (FIPS) test. The originality and value of this paper is that this is the first study that uses the panel unit root tests to examine unemployment dynamics in the Estonian regions. The findings revea...

  1. Estonian waterworks treatment plants: clearance of residues, discharge of effluents and efficiency of removal of radium from drinking water.

    Science.gov (United States)

    Trotti, F; Caldognetto, E; Forte, M; Nuccetelli, C; Risica, S; Rusconi, R

    2013-12-01

    Considerable levels of radium were detected in a certain fraction of the Estonian drinking water supply network. Some of these waterworks have treatment systems for the removal of (mainly) iron and manganese from drinking water. Three of these waterworks and another one equipped with a radium removal pilot plant were examined, and a specific study was conducted in order to assess the environmental compatibility of effluents and residues produced in the plants. (226)Ra and (228)Ra activity concentrations were analysed in both liquid (backwash water) and solid (sand filter and sediment) materials to evaluate their compliance, from the radiological point of view, with current Estonian legislation and international technical documents that propose reference levels for radium in effluents and residues. Also with regard to water treatment by-products, a preliminary analysis was done of possible consequences of the transposition of the European Basic Safety Standards Draft into Estonian law. Radium removal efficiency was also tested in the same plants. Iron and manganese treatment plants turned out to be scarcely effective, whilst the radium mitigation pilot plant showed a promising performance.

  2. Motivational Underpinnings of Estonian Folk Dance Practices among the Estonian Diaspora over Time

    OpenAIRE

    Eha Rüütel; Iivi Zajedova; Angela Arraste

    2013-01-01

    This article is a part of a wider research on Estonian folk dance, aiming to map the emergence of folk dance groups and to study the practices and role of folk dance among the Estonian diaspora. The article sets out to explore incentives contributing to intergenerational transmission of Estonian folk dance tradition. 54 interviews (21 men and 33 women aged 38 to 87) were carried out with Estonians living in Australia, Canada, Germany, Great Britain, Sweden and the United States. The analysis ...

  3. Cohort Profile : Estonian Biobank of the Estonian Genome Center, University of Tartu

    NARCIS (Netherlands)

    Leitsalu, Liis; Haller, Toomas; Esko, Tonu; Tammesoo, Mari-Liis; Alavere, Helene; Snieder, Harold; Perola, Markus; Ng, Pauline C.; Maegi, Reedik; Milani, Lili; Fischer, Krista; Metspalu, Andres

    The Estonian Biobank cohort is a volunteer-based sample of the Estonian resident adult population (aged >= 18 years). The current number of participants-close to 52000-represents a large proportion, 5%, of the Estonian adult population, making it ideally suited to population-based studies. General

  4. Reference test courses for autonomous mobile robots

    Science.gov (United States)

    Jacoff, Adam; Messina, Elena; Evans, John

    2001-09-01

    One approach to measuring the performance of intelligent systems is to develop standardized or reproducible tests. These tests may be in a simulated environment or in a physical test course. The National Institute of Standards and Technology has developed a test course for evaluating the performance of mobile autonomous robots operating in an urban search and rescue mission. The test course is designed to simulate a collapsed building structure at various levels of fidelity. The course will be used in robotic competitions, such as the American Association for Artificial Intelligence (AAAI) Mobile Robot Competition and the RoboCup Rescue. Designed to be repeatable and highly reconfigurable, the test course challenges a robot's cognitive capabilities such as perception, knowledge representation, planning, autonomy and collaboration. The goal of the test course is to help define useful performance metrics for autonomous mobile robots which, if widely accepted, could accelerate development of advanced robotic capabilities by promoting the re-use of algorithms and system components. The course may also serve as a prototype for further development of performance testing environments which enable robot developers and purchasers to objectively evaluate robots for a particular application. In this paper we discuss performance metrics for autonomous mobile robots, the use of representative urban search and rescue scenarios as a challenge domain, and the design criteria for the test course.

  5. Schults suurendas kaalu Estonian Airis / Kadri Paas

    Index Scriptorium Estoniae

    Paas, Kadri, 1982-

    2010-01-01

    Estonian Airi nõukogu esimees, AS-i Cresco üks omanikke Olev Schults ostis ärimees Tõnu Laagilt tema osaluse Crescos ja selle tütarfirmades, saades täieliku kontrolli Cresco ja ühtlasi Estonian Airi 17-protsendilise osaluse üle

  6. Estonian Air andis muutustest teada / Mart Relve

    Index Scriptorium Estoniae

    Relve, Mart, 1973-

    2006-01-01

    Autor peab kahetsusväärseks, et Äripäev süüdistab Estonian Air'i avalikkuse eest info varjamises ning kasutab oma väidete tõestuseks avalikkuses jutuks olnud fakte. Vt. samas: Estonian Air saanud meedias kriitikat

  7. Estonian Golf & Country Club / Urmas Oja

    Index Scriptorium Estoniae

    Oja, Urmas, 1981-2012

    2005-01-01

    Konkursil "Eesti parim puitehitis 2005" pälvis voodrilaua eripreemia Jõelähtme Estonian Golf & Country Club'i katus. Arhitekt Andres Siim. Sisearhitekt Juta Lember. Konstruktor: AS Resand. 11 värv. ill

  8. Estonian Air to overhaul strategy / Matt Withers

    Index Scriptorium Estoniae

    Withers, Matt

    2008-01-01

    Estonian Air on majanduslikes raskustes, mida aitaks leevendada riigipoolne toetus. Majandus- ja kommunikatsiooniminister Juhan Parts leiab, et riik peaks omama lennufirma juhatuses esimehe kohta, et mõjutada rohkem vastuvõetavaid otsuseid ja investeeringuid

  9. On the System of Person-Denoting Signs in Estonian Sign Language: Estonian Name Signs

    Science.gov (United States)

    Paales, Liina

    2010-01-01

    This article discusses Estonian personal name signs. According to study there are four personal name sign categories in Estonian Sign Language: (1) arbitrary name signs; (2) descriptive name signs; (3) initialized-descriptive name signs; (4) loan/borrowed name signs. Mostly there are represented descriptive and borrowed personal name signs among…

  10. Estonian and Russian Federation amoxicillin formulations: a comparative study of in vitro dissolution.

    Science.gov (United States)

    Bronnikova, O; Matto, V; Meos, A

    2008-06-01

    The in vitro dissolution properties were compared for four different formulations from the Estonian drug market and four from the Russian Federation drug market. Seven of the eight formulations tested released at least 75% or 80% amoxicillin during 30- or 90-min dissolution tests (37 degrees C, purified water, 75 rpm), respectively. One marketed Russian Federation formulation released 74% amoxicillin over a 90-min period. The present study shows that, in general, the in vitro dissolution properties of the Russian Federation amoxicillin formulations are, with some minor exceptions, comparable to those of the Estonian formulations. Copyright 2008 Prous Science, S.A.U. or its licensors. All rights reserved.

  11. Testing and reference model analysis of FTTH system

    Science.gov (United States)

    Feng, Xiancheng; Cui, Wanlong; Chen, Ying

    2009-08-01

    With rapid development of Internet and broadband access network, the technologies of xDSL, FTTx+LAN , WLAN have more applications, new network service emerges in endless stream, especially the increase of network game, meeting TV, video on demand, etc. FTTH supports all present and future service with enormous bandwidth, including traditional telecommunication service, traditional data service and traditional TV service, and the future digital TV and VOD. With huge bandwidth of FTTH, it wins the final solution of broadband network, becomes the final goal of development of optical access network.. Fiber to the Home (FTTH) will be the goal of telecommunications cable broadband access. In accordance with the development trend of telecommunication services, to enhance the capacity of integrated access network, to achieve triple-play (voice, data, image), based on the existing optical Fiber to the curb (FTTC), Fiber To The Zone (FTTZ), Fiber to the Building (FTTB) user optical cable network, the optical fiber can extend to the FTTH system of end-user by using EPON technology. The article first introduced the basic components of FTTH system; and then explain the reference model and reference point for testing of the FTTH system; Finally, by testing connection diagram, the testing process, expected results, primarily analyze SNI Interface Testing, PON interface testing, Ethernet performance testing, UNI interface testing, Ethernet functional testing, PON functional testing, equipment functional testing, telephone functional testing, operational support capability testing and so on testing of FTTH system. ...

  12. Air Baltic: Estonian Air on nurka surutud / Teele Tammeorg

    Index Scriptorium Estoniae

    Tammeorg, Teele

    2010-01-01

    Air Balticu asepresidendi Janis Vanagsi hinnangul on Estonian Air aastaid jätnud tähelepanuta oma peamised turismiturud ning on praegu halvas seisus. Air Baltic on endiselt huvitatud Estonian Airi ostust. Majandus- ja kommunikatsiooniminister Juhan Partsi seisukoht

  13. Estonian and Russian Parental Attitudes to Childrearing and Play.

    Science.gov (United States)

    Saar, Aino; Niglas, Katrin

    2001-01-01

    Used Neukater and van der Kooji's parental attitude questionnaire to ask three groups of mothers (Estonian, non-Estonian in Estonia, Russians in Moscow) about their attitudes toward children's education and play. Found that Estonian mothers applied least control and that higher mother education resulted in less child control and instruction. (DLH)

  14. Reference architecture for interoperability testing of Electric Vehicle charging

    NARCIS (Netherlands)

    Lehfuss, F.; Nohrer, M.; Werkmany, E.; Lopezz, J.A.; Zabalaz, E.

    2015-01-01

    This paper presents a reference architecture for interoperability testing of electric vehicles as well as their support equipment with the smart grid and the e-Mobility environment. Pan-European Electric Vehicle (EV)-charging is currently problematic as there are compliance and interoperability

  15. Reference values for paediatric pulmonary function testing: The Utrecht dataset.

    Science.gov (United States)

    Koopman, Marije; Zanen, Pieter; Kruitwagen, Cas L J J; van der Ent, Cornelis K; Arets, Hubertus G M

    2011-01-01

    Since populations evolve, measurement protocols and equipment improve and analysis techniques progress, there is an ongoing need to reassess reference data for pulmonary function tests. Furthermore, reference values for total lung capacity and carbon monoxide diffusion capacity are scarcely available in children. We aimed to provide updated reference equations for most commonly used pulmonary function indices in Caucasian children. In the 'Utrecht Pulmonary Function Reference Data Study' we collected data in Caucasian children aged 2-18 years. We analyzed them using the 'Generalized Additive Models for Location Scale and Shape' (GAMLSS) statistical method. Measurements of interrupter resistance (R(int)) (n = 877), spirometry (n = 1042), body plethysmography (n = 723) and carbon monoxide diffusion/helium dilution (n = 543) were obtained in healthy children. Height (or the natural logarithm of height) and age (or the natural logarithm of age) were both significantly related to most outcome measures. Also sex was a significant determinant, except for RV, RV/TLC, FRC(pleth), Raw(0,5), Raw(tot), R(int) and FEF values. The application of previously published reference equations on the study population resulted in misinterpretation of pulmonary function. These new paediatric reference equations provide accurate estimates of the range of normality for most commonly used pulmonary function indices, resulting in less underdiagnosis and overdiagnosis of pulmonary diseases. Copyright © 2010 Elsevier Ltd. All rights reserved.

  16. Data Link Test and Analysis System/ATCRBS Transponder Test System Technical Reference

    Science.gov (United States)

    1990-05-01

    This document references material for personnel using or making software changes : to the Data Link Test and Analysis System (DATAS) for Air Traffic Control Radar : Beacon System (ATCRBS) transponder testing and data collection. This is one of : a se...

  17. Reference Values of Pulmonary Function Tests for Canadian Caucasians

    Directory of Open Access Journals (Sweden)

    Carlos Gutierrez

    2004-01-01

    Full Text Available A multicentre, cross-sectional study was carried out in six centres across Canada to establish a national standard for pulmonary function tests using healthy, lifetime nonsmokers, with each centre aiming to test 10 men and 10 women from each decade from 20 to 80 years of age. Data from each centre were used to derive prediction equations for each centre, and pooled data from all centres (total: 327 women and 300 men were used to derive Canadian predicted equations. The predictive models were compared with three widely used published models for selected tests. It was found that, in general, the equations modelled for each centre could be replaced by the models obtained when pooling all data (Canadian model. Comparisons with the published references showed good agreement and similar slopes for most tests. The results suggest that pulmonary function test results obtained from different centres in Canada were comparable and that standards currently used remain valid for Canadian Caucasians.

  18. Stocks of organic carbon in Estonian soils

    Directory of Open Access Journals (Sweden)

    Kõlli, Raimo

    2009-06-01

    Full Text Available The soil organic carbon (SOC stocks (Mg ha–1 ofautomorphic mineral (9 soil groups, hydromorphic mineral (7, and lowland organic soils (4 are given for the soil cover or solum layer as a whole and also for its epipedon (topsoil layer. The SOC stocks for forest, arable lands, and grasslands and for the entire Estonian soil cover were calculated on the basis of the mean SOC stock and distribution area of the respective soil type. In the Estonian soil cover (42 400 km2, a total of 593.8 ± 36.9 Tg of SOC is retained, with 64.9% (385.3 ± 27.5 Tg in the epipedon layer (O, H, and A horizons and 35.1% in the subsoil (B and E horizons. The pedo-ecological regularities of SOC retention in soils are analysed against the background of the Estonian soil ordination net.

  19. Unemployment hysteresis in the “Nordic Kitten”: Evidence from five Estonian regions

    Directory of Open Access Journals (Sweden)

    Furuoka Fumitaka

    2015-01-01

    Full Text Available Unemployment hysteresis is a much discussed and researched topic in macroeconomics. The present paper examined unemployment hysteresis in five Estonian regions. It used two panel data methods, namely, the Im-Pesaran-Shin (IPS test and the Fourier Im-Pesaran-Shin (FIPS test. The originality and value of this paper is that this is the first study that uses the panel unit root tests to examine unemployment dynamics in the Estonian regions. The findings revealed that the unemployment rates in the Estonian regions could be best described as a stationary process. This result is in line with the natural rate hypothesis. A research implication is that this study has illustrated that nonlinear tests could be an appropriate approach to examine unemployment hysteresis because other methods may fail to reject the null hypothesis. A practical implication of this study is that it sheds light on the nature of unemployment dynamics in Estonia at the regional level. As the findings revealed, the unemployment rates in the Estonian regions had the meanreversion property. Therefore, the higher-than-normal unemployment rates are likely to return to the natural level even in the absence of intervention policies initiated by the government or policy makers.

  20. [Reference Intervals of Standard Test Items in Ningen Dock Examination].

    Science.gov (United States)

    Yamakado, Minoru

    2016-03-01

    Reference intervals (RIs) were derived from records of 1,499,288 individuals who underwent ningen dock examination in 188 institutes which belong to Japan Society of Ningen Dock in 2012. Targets were 27 basic laboratory tests, including the body mass index (BMI) and systolic and diastolic blood pressures (SBP, DBP). Individuals fulfilling strict criteria were chosen: SBP dock results will enable the appropriate interpretation of test results in health screening, and promote the effective application of CDLs for therapeutic intervention, taking into account the sex, age, and other health attributes.

  1. Estonian Literature in the Schools of the Estonian-Russian Population (Changes in Literacy).

    Science.gov (United States)

    Ots, Loone

    1997-01-01

    Describes how Estonian language and literature have been taught at Russian-language schools in Estonia. Notes a lack of interesting reading materials, and describes how this instruction could be improved. (SR)

  2. Effects of Reference Performance Testing During Aging Using Commercial Cells

    Energy Technology Data Exchange (ETDEWEB)

    Jon P. Christophersen; Chinh D. Ho; David Howell

    2005-07-01

    The Advanced Technology Development Program, under the oversight of the U.S. Department of Energy’s FreedomCAR and Vehicle Technologies Program, is investigating lithium-ion batteries for hybrid-electric vehicle applications. Cells are aged under various test conditions, including temperatures and states-of-charge. Life testing is interrupted at regular intervals to conduct reference performance tests (RPTs), which are used to measure changes in the electrical performance of the cells and then to determine cell degradation as a function of test time. Although designed to be unobtrusive, data from the Advanced Technology Development Gen 2 cells indicated that RPTs actually contributed to cell degradation and failure. A study was performed at the Idaho National Laboratory using commercially available lithium-ion cells to determine the impact of RPTs on life. A series of partial RPTs were performed at regular intervals during life testing and compared to a control group that was life tested without RPT interruption. It was determined that certain components of the RPT were detrimental, while others appeared to improve cell performance. Consequently, a new "mini" RPT was designed as an unobtrusive alternative. Initial testing with commercial cells indicates that the impact of the mini RPT is significantly less than the Gen 2 cell RPT.

  3. Transformational Leadership in the Estonian Defence Forces

    Directory of Open Access Journals (Sweden)

    Antek Kasemaa

    2015-06-01

    Full Text Available Purpose – The study is a contribution to the validation of the 15 items and 5 subscales Transformational Leadership Scale (TLS proposed by Rafferty and Griffin (2004. Design/methodology/approach – The sample includes participants from different levels of the Estonian Defence Forces (EDF military hierarchy (N=2570. The structure of the TLS was examined by using exploratory and confirmatory factor analyses. Additionally ANOVA was used to compare the results between different subsamples. Findings – TLS showed satisfactory reliability. Confirmatory factor analyses found TLS as valid five dimensions instrument to measure transformational leadership in the Estonian military context. Different management levels showed different emphases among the dimensions of transformational leadership. Research and practical limitations/implications – TLS will be an important tool to use in transformational leadership research in the Estonian military context and beyond. Additionally, the current research contributes to the development of alternative measurement tools besides the most commonly used MLQ. The limitation of the work will be the rather homogenous sample from the Estonian military, however it will open the door for the subsequent research using different samplings. Originality/value – The current research found TLS to be a reliable and valid instrument, very short and therefore easy to administrate, having the possibility to use it with five dimensional and as one general transformational instrument as well.

  4. Valued Estonian Music CDs / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2003-01-01

    2002. aastal välja antud eesti muusika heliplaatidest Arvo Pärt "Summa", Lepo Sumera "Chamber Music", "Baltic Voices 1.", "Sequenzen - Europäische Orgelmusik des 20. Jahrhundrets mit...", "El silenco ئ Silence. Kuldar and Marje Sink. Songs of Mother and Son", "Riho Sibul. Estonian Dream Big Band", "Rull's Royce ئ Rull's Choice"

  5. English in the Estonian Multicultural Society.

    Science.gov (United States)

    Fonzari, Lorena

    1999-01-01

    Argues that the spread of English is not closely associated to a discourse of linguistic imperialism, basing the thesis on a case study in Estonia. Surveys of three generations of Estonians indicated that all welcomed English as a means of communications and technology in the modern world, reacting against the imposition of Russian language and…

  6. Impact of Relationships between Test and Reference Animals and between Reference Animals on Reliability of Genomic Prediction

    DEFF Research Database (Denmark)

    Wu, Xiaoping; Lund, Mogens Sandø; Sun, Dongxiao

    This study investigated reliability of genomic prediction in various scenarios with regard to relationship between test and reference animals and between animals within the reference population. Different reference populations were generated from EuroGenomics data and 1288 Nordic Holstein bulls a...

  7. Towards a standardized reference point indentation testing procedure.

    Science.gov (United States)

    Setters, Alexander; Jasiuk, Iwona

    2014-06-01

    We study the reference point indentation (RPI) technique which has a potential to directly measure mechanical properties of bone in patients. More specifically, we tested 6 month swine femoral cortical bone at mid-diaphysis region to investigate the effect of several testing variables on the RPI outputs. They include the force magnitude, preconditioning, variation within a sample and between samples, number of cycles, indentation surface (transverse versus longitudinal, polished versus unpolished), and micro-computed tomography radiation exposure. The force magnitude variation test shows that all RPI parameters increase linearly with the increasing force magnitude except the indentation distance increase which shows a cubic trend with a plateau for force magnitudes between 4N and 8N. Preconditioning does not affect the trends for a force magnitude variation test. The cycle variation test shows that most RPI parameters reach either a maximum or minimum at 15-20 cycles. Transverse surface measurements are more consistent than the longitudinal surface measurements, but a rough surface and periosteum on the longitudinal surface could account for this difference. Exposure to the micro-computed tomography radiation in general does not have effect on the RPI measurements. For the 6 month swine femoral cortical bone, testing using 6N force and 20 cycles with preconditioning on an unpolished longitudinal surface is recommended. This study advances our knowledge on how the RPI testing variables influence the RPI outputs and provides guidance on the RPI measurements. It may also serve as a framework for developing a standardized testing procedure for the RPI technique. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Impact of Relationships between Test and Reference Animals and between Reference Animals on Reliability of Genomic Prediction

    DEFF Research Database (Denmark)

    Wu, Xiaoping; Lund, Mogens Sandø; Sun, Dongxiao

    as a common test population. A GBLUP model and a Bayesian mixture model were applied to predict Genomic breeding values for bulls in the test data. Result showed that a closer relationship between test and reference animals led to a higher reliability, while a closer relationship between reference animal...... resulted in a lower reliability. Therefore, the design of reference population is important for improving the reliability of genomic prediction. With regard to model, the Bayesian mixture model in general led to slightly a higher reliability of genomic prediction than the GBLUP model......This study investigated reliability of genomic prediction in various scenarios with regard to relationship between test and reference animals and between animals within the reference population. Different reference populations were generated from EuroGenomics data and 1288 Nordic Holstein bulls...

  9. Towards a new reference test for surra in camels.

    Science.gov (United States)

    Tran, Thao; Claes, Filip; Verloo, Didier; De Greve, Henri; Büscher, Philippe

    2009-07-01

    Current serological diagnosis of Trypanosoma evansi infection in camels is based on the native variable antigen type RoTat 1.2. The goal of this study was to develop a novel serological diagnostic test based on a nonvariable protein and freed from the use of rats or mice for its production. An enzyme-linked immunosorbent assay using a recombinant extracellular domain of invariant surface glycoprotein 75 (ELISA/rISG75) was developed and tested on a collection of 184 camel sera. The results were compared to those obtained from three established antibody detection tests based on variable surface glycoprotein RoTat 1.2: an ELISA for T. evansi (ELISA/T. evansi), a card agglutination test for trypanosomiasis (CATT/T. evansi), and an immune trypanolysis (TL) assay. The ELISA/rISG75 and the ELISA/T. evansi showed a sensitivity of 94.6% (95% confidence interval [CI], 87.8 to 98.2%, at 19% positivity cutoff value) and 98.9% (95% CI, 94.1 to 99.8, at 12% positivity cutoff value), respectively. The ELISA/rISG75 had 100% specificity (CI, 95.9 to 100%), while the ELISA/T. evansi showed 98.9% specificity (CI, 95.9 to 100%). The ELISA/rISG75 demonstrated an almost perfect agreement with the TL assay, the CATT/T. evansi, and the ELISA/T. evansi, with kappa scores of at least 0.94. The ELISA/rISG75, having a performance comparable to that of the gold standard (the TL assay) and being independent of antigenic variation, may become a new reference test for surra in camels. It opens avenues for the diagnosis of T. evansi infections in other hosts as well as for the development of a pan-Trypanozoon test for detection of Trypanosoma brucei brucei, T. b. gambiense, T. b. rhodesiense, T. evansi, and T. equiperdum.

  10. Somatotype in 6-11-year-old Italian and Estonian schoolchildren.

    Science.gov (United States)

    Ventrella, A R; Semproli, S; Jürimäe, J; Toselli, S; Claessens, A L; Jürimäe, T; Brasili, P

    2008-01-01

    The study of somatotypes can contribute to the understanding of variability in human body build. The aim of this study was to compare the somatotypes of Italian and Estonian schoolchildren in order to evaluate factors that might lead to variability in somatotypes. The sample consisted of 762 Italian and 366 Estonian children aged 6-11 years. They were somatotyped by the Heath-Carter anthropometric method. Data on organised extra-curricular physical activity and hours of weekly training were also collected. One-way ANOVA was used to evaluate country-related variations of somatotype in each age/sex group, while factorial ANOVA was used to test the influence of country and organised physical activity on the variability of the anthropometric characteristics and somatotype components. There are significant differences in mean somatotypes between the Italian and Estonian children in many age classes and a different constitutional trend in children from the two different countries is observed. The Italian children are more endomorphic and less mesomorphic and ectomorphic than the Estonian children. On the other hand, it emerges from factorial ANOVA, that the somatotype components do not present significant variations related to organised physical activity and to the interaction between the country of origin and sport practice. Moreover, the results of the forward stepwise discriminant analyses show that mesomorphy is the best discriminator between the two countries, followed by ectomorphy. Our findings suggest that the observed differences between Italian and Estonian children could be related mainly to country rather than to the practice of organised physical activity in the two countries.

  11. Estonian Middle Semantics with Evidence from Discourse

    Directory of Open Access Journals (Sweden)

    Virve-Anneli Vihman

    2004-01-01

    Full Text Available This paper presents arguments for recognizing a middle voice in Estonian. The claim that the semantics of middle-marked verbs differs in a substantial way from the semantics of other intransitive constructions leads to the examination of the discourse pragmatics of these constructions, and the relationship between discourse patterns and their valency and argument properties. Various topicality measures show that the argument participant in middle clauses lies between that of the sole participant (S in intransitive clauses and the O of active transitive clauses. The results regarding the discourse behaviour of middle arguments constitute new evidence for the view that middle constructions differ from ordinary intransitive verbs, despite structural similarities, and mark a unique range on the scale of transitivity exhibited by verbs in Estonian.

  12. Transformational Leadership in the Estonian Defence Forces

    OpenAIRE

    Antek Kasemaa

    2015-01-01

    Purpose – The study is a contribution to the validation of the 15 items and 5 subscales Transformational Leadership Scale (TLS) proposed by Rafferty and Griffin (2004). Design/methodology/approach – The sample includes participants from different levels of the Estonian Defence Forces (EDF) military hierarchy (N=2570). The structure of the TLS was examined by using exploratory and confirmatory factor analyses. Additionally ANOVA was used to compare the results between different subsamples....

  13. Level of knowledge and sources of information about the rheumatoid arthritis in Estonian patients.

    Science.gov (United States)

    Põlluste, Kaja; Kallikorm, Riina; Lember, Margus

    2014-05-01

    The objective of this paper was to find out how many patients with rheumatoid arthritis (RA) know about several aspects of disease, to explain the associations between the level of self-rated knowledge and patients' background and health status and to compare the importance of the main sources of information. A random sample (n = 1,259) of adult Estonian RA patients was selected from the Estonian Health Insurance Fund Database. The patients completed a self-administered questionnaire, which included information about their socio-demographic and disease characteristics, use of health services, information about the disease, and sources of information. Regression analysis was used to calculate the associations between the independent variables and level of self-rated knowledge about several aspects of RA. The results of the study indicated that the self-reported ratings of knowledge about the disease in Estonian RA patients were rather low. Health professionals were mentioned as the primary sources of information, but the longer disease history and more frequent use of health services as considerable predictors of higher ratings of knowledge refer to role of personal experience in obtaining knowledge about the disease as well.

  14. Development of a diagnostic test based on multiple continuous biomarkers with an imperfect reference test.

    Science.gov (United States)

    García Barrado, Leandro; Coart, Els; Burzykowski, Tomasz

    2016-02-20

    Ignoring the fact that the reference test used to establish the discriminative properties of a combination of diagnostic biomarkers is imperfect can lead to a biased estimate of the diagnostic accuracy of the combination. In this paper, we propose a Bayesian latent-class mixture model to select a combination of biomarkers that maximizes the area under the ROC curve (AUC), while taking into account the imperfect nature of the reference test. In particular, a method for specification of the prior for the mixture component parameters is developed that allows controlling the amount of prior information provided for the AUC. The properties of the model are evaluated by using a simulation study and an application to real data from Alzheimer's disease research. In the simulation study, 100 data sets are simulated for sample sizes ranging from 100 to 600 observations, with a varying correlation between biomarkers. The inclusion of an informative as well as a flat prior for the diagnostic accuracy of the reference test is investigated. In the real-data application, the proposed model was compared with the generally used logistic-regression model that ignores the imperfectness of the reference test. Conditional on the selected sample size and prior distributions, the simulation study results indicate satisfactory performance of the model-based estimates. In particular, the obtained average estimates for all parameters are close to the true values. For the real-data application, AUC estimates for the proposed model are substantially higher than those from the 'traditional' logistic-regression model. Copyright © 2015 John Wiley & Sons, Ltd.

  15. Developing a list of reference chemicals for testing alternatives to whole fish toxicity tests.

    Science.gov (United States)

    Schirmer, Kristin; Tanneberger, Katrin; Kramer, Nynke I; Völker, Doris; Scholz, Stefan; Hafner, Christoph; Lee, Lucy E J; Bols, Niels C; Hermens, Joop L M

    2008-11-11

    This paper details the derivation of a list of 60 reference chemicals for the development of alternatives to animal testing in ecotoxicology with a particular focus on fish. The chemicals were selected as a prerequisite to gather mechanistic information on the performance of alternative testing systems, namely vertebrate cell lines and fish embryos, in comparison to the fish acute lethality test. To avoid the need for additional experiments with fish, the U.S. EPA fathead minnow database was consulted as reference for whole organism responses. This database was compared to the Halle Registry of Cytotoxicity and a collation of data by the German EPA (UBA) on acute toxicity data derived from zebrafish embryos. Chemicals that were present in the fathead minnow database and in at least one of the other two databases were subject to selection. Criteria included the coverage of a wide range of toxicity and physico-chemical parameters as well as the determination of outliers of the in vivo/in vitro correlations. While the reference list of chemicals now guides our research for improving cell line and fish embryo assays to make them widely applicable, the list could be of benefit to search for alternatives in ecotoxicology in general. One example would be the use of this list to validate structure-activity prediction models, which in turn would benefit from a continuous extension of this list with regard to physico-chemical and toxicological data.

  16. Estimation of reference values for liver function test analytes in ...

    African Journals Online (AJOL)

    The piccolo expressanalyzer screened for Albumin, Alanine Transaminase (ALT), AspartateTransaminase (AST), Total Protein (TP), Gamma Glutamine Transferase (GGT) and Total Bilirubin (TBIL). Results: Reference ranges were constructed using non-parametric methods to estimate 2.5 and 97.5 percentiles of distribution ...

  17. Estonian greenhouse gas emissions inventory report

    Energy Technology Data Exchange (ETDEWEB)

    Punning, J.M.; Ilomets, M.; Karindi, A.; Mandre, M.; Reisner, V. [Inst. of Ecology, Tallinn (Estonia); Martins, A.; Pesur, A. [Inst. of Energy Research, Tallinn (Estonia); Roostalu, H.; Tullus, H. [Estonian Agricultural Univ., Tartu (Estonia)

    1996-07-01

    It is widely accepted that the increase of greenhouse gas concentrations in the atmosphere due to human activities would result in warming of the Earth`s surface. To examine this effect and better understand how the GHG increase in the atmosphere might change the climate in the future, how ecosystems and societies in different regions of the World should adapt to these changes, what must policymakers do for the mitigation of that effect, the worldwide project within the Framework Convention on Climate Change was generated by the initiative of United Nations. Estonia is one of more than 150 countries, which signed the Framework Convention on Climate Change at the United Nations Conference on Environment and Development held in Rio de Janeiro in June 1992. In 1994 a new project, Estonian Country Study was initiated within the US Country Studies Program. The project will help to compile the GHG inventory for Estonia, find contemporary trends to investigate the impact of climate change on the Estonian ecosystems and economy and to formulate national strategies for Estonia addressing to global climate change.

  18. MINORITY LANGUAGES IN ESTONIAN SEGREGATIVE LANGUAGE ENVIRONMENTS

    Directory of Open Access Journals (Sweden)

    Elvira Küün

    2011-01-01

    Full Text Available The goal of this project in Estonia was to determine what languages are spoken by students from the 2nd to the 5th year of basic school at their homes in Tallinn, the capital of Estonia. At the same time, this problem was also studied in other segregated regions of Estonia: Kohtla-Järve and Maardu. According to the database of the population census from the year 2000 (Estonian Statistics Executive Office's census 2000, there are representatives of 142 ethnic groups living in Estonia, speaking a total of 109 native languages. At the same time, the database doesn’t state which languages are spoken at homes. The material presented in this article belongs to the research topic “Home Language of Basic School Students in Tallinn” from years 2007–2008, specifically financed and ordered by the Estonian Ministry of Education and Research (grant No. ETF 7065 in the framework of an international study called “Multilingual Project”. It was determined what language is dominating in everyday use, what are the factors for choosing the language for communication, what are the preferred languages and language skills. This study reflects the actual trends of the language situation in these cities.

  19. Utilisation of Estonian energy wood resources

    Energy Technology Data Exchange (ETDEWEB)

    Muiste, P.; Tullus, H.; Uri, V. [Estonian Agricultural University, Tartu (Estonia)

    1996-12-31

    In the end of the Soviet period in the 1980s, a long-term energy programme for Estonia was worked out. The energy system was planned to be based on nuclear power and the share of domestic alternative sources of energy was low. The situation has greatly changed after the re-establishment of the Estonian independence, and now wood and peat fuels play an important role in the energy system. Energy consumption in Estonia decreased during the period 1970-1993, but this process has less influenced the consumption of domestic renewable fuels - peat and wood. It means that the share of these fuels has grown. The investment on substitution of imported fossil fuels and on conversion of boiler plants from fossil fuels to domestic fuels has reached the level of USD 100 million. The perspectives of the wood energy depend mainly on two factors; the resources and the price of wood energy compared with other fuels. The situation in wood market influences both the possible quantities and the price. It is typical that the quickly growing cost of labour power in Estonia is greatly affecting the price of energy wood. Though the price level of fuel peat and wood chips is lower than the world market price today, the conditions for using biofuels could be more favourable, if higher environmental fees were introduced. In conjunction with increasing utilisation of biofuels it is important to evaluate possible emissions or removal of greenhouse gases from Estonian forests 3 refs.

  20. No association between vitamin D and β-cell autoimmunity in Finnish and Estonian children.

    Science.gov (United States)

    Reinert-Hartwall, L; Honkanen, J; Härkönen, T; Ilonen, J; Simell, O; Peet, A; Tillmann, V; Lamberg-Allardt, C; Virtanen, S M; Knip, M; Vaarala, O

    2014-11-01

    Vitamin D has immunomodulatory properties, such as regulation of FOXP3 expression and regulatory T-cell activity. Our aim was to investigate whether plasma 25-hydroxyvitamin D [25(OH)D] concentrations associate with the development of β-cell autoimmunity and the transcriptional activity of FOXP3 or vitamin D3 convertase gene (CYP27B1) in CD4+ memory T cells. We studied 83 Finnish and 32 Estonian children participating in the DIABIMMUNE and DIPP studies. Twenty-nine Finnish and six Estonian children tested positive for at least one diabetes-associated autoantibody. The plasma concentrations of 25(OH)D and 1,25(OH)₂D were analysed with an enzyme immunoassay. Gene expression of FOXP3 and CYP27B1 in the isolated CD4+ memory T cells was studied with reverse transcription quantitative polymerase chain reaction. Vitamin D status did not differ between subjects positive and negative for β-cell autoantibodies. Finnish children had higher vitamin D status than Estonian children (p Estonian CD4+ memory T-cell samples than in Finnish samples (p < 0.01) even when including in both groups only children with serum 25(OH)D concentrations in the range of 50-80 nmol/L (p < 0.001). These findings do not support a crucial role of circulating 25(OH)D as a regulator of β-cell autoimmunity or FOXP3 expression. Copyright © 2014 John Wiley & Sons, Ltd.

  1. Experimental Test Plan DOE Tidal and River Reference Turbines

    Energy Technology Data Exchange (ETDEWEB)

    Neary, Vincent S [ORNL; Hill, Craig [St. Anthony Falls Laboratory, 2 Third Avenue SE, Minneapolis, MN 55414; Chamorro, Leonardo [St. Anthony Falls Laboratory, 2 Third Avenue SE, Minneapolis, MN 55414; Gunawan, Budi [ORNL

    2012-09-01

    Our aim is to provide details of the experimental test plan for scaled model studies in St. Anthony Falls Laboratory (SAFL) Main Channel at the University of Minnesota, including a review of study objectives, descriptions of the turbine models, the experimental set-up, instrumentation details, instrument measurement uncertainty, anticipated experimental test cases, post-processing methods, and data archiving for model developers.

  2. Paediatric lung function testing : determinants and reference values

    NARCIS (Netherlands)

    Koopman, Marije

    2011-01-01

    Paediatric lung function tests provide objective measures in diagnosis and follow-up of lung diseases, and give insight in the pathophysiology of lung growth and development. In the first part of the thesis, paediatric lung function tests were used to investigate determinants of lung growth and

  3. Eesti antiigitõlke traditsioonid / Traditions of Estonian Translation from Ancient Greek and Latin

    Directory of Open Access Journals (Sweden)

    Janika Päll

    2012-06-01

    Full Text Available The tradition of translating ancient Greek and Roman authors into Estonian is short, beginning with first attempts at the end of the 18 th century and the close adaptations of two Anacreontic poems (21 and 24 by the first Estonian poet Kristjan Jaak Peterson (in 1818, which remained in manuscript for a long time. The continuous history of printed translations began in 1878 with the translations from Homer by Jaan Bergmann. At present, a new, extensive and regularly updated bibliography with a database of earlier translations is being created (EAB 2012, which also includes the translations in the journals and more extensive citations in articles, as printing separate books with ancient literature started very late (1908 and was very rare in the beginning.  The periods in Estonian translation reflect the history of the country. Almost every period has its own specific trends, beginning with the focus on Greek and the role of periodicals in the first, resembling the patchwork-model of translation that has been described by Karl Eimermacher. Alongside the wish to entertain and educate, we see a strong tendency to use these translations for the development of Estonian national identity by comparing the Estonian epic “Kalevipoeg” to Homer’s epics and translating pieces from Tacitus’ “Germania” as early references to Estonia and thereby extending Estonia’s written history.  The 1920s and 1930s bring first attempts to create a canon, with a stress on Latin and the translations made for school, as well as the development of verse translation. However, all this was disrupted by the almost total abandonment of the classical tradition during the war and the Stalinist period. The comeback in the 1960s brought the translation of central authors from the classical canon (Homer, Vergil, Sophocles, supported by other activities of canon-building (anticipated partly in the 1920s and 1930s: the composition of anthologies and histories of literature

  4. Quantitative and qualitative aspects of switching between Estonian Sign Language and spoken Estonian

    Directory of Open Access Journals (Sweden)

    Kadri Hein

    2013-04-01

    Full Text Available The central research question of the present paper is ‘What variables influence switching (code-switching and code-blending between Estonian Sign Language and spoken Estonian among bimodal bilinguals in a school environment?’ The data from guided discussions involving deaf and hearing students indicated that bimodal bilinguals predominantly code-blend, i.e. simultaneously produce speech and signs. The main function of switching among the students was to emphasise a constituent in a clause, but they also switched to express themselves in an original way. In some utterances, it proved difficult to apply a single function to a switch, thus a sequential turn-by-turn analysis was employed. A deaf student’s level of switching was influenced most by the hearing status of the interlocutor, and the amount of switching by the interlocutor.DOI: http://dx.doi.org/10.5128/ERYa9.03

  5. External factors and the interference of L1 Estonian on L2 English pronunciation: An apparent-time study

    Directory of Open Access Journals (Sweden)

    Kristiina Ader

    2015-04-01

    Full Text Available This study focusses on external factors of second language learning (L2 and their effect on L2 sound production. The aim was to find out whether young adults whose first language (L1 is Estonian speak L2 English with less accent than older speakers of L1 Estonian. Prior studies have claimed that more exposure to the target language lessens the effect of L1 interference (internal factors (e.g. Piske et al. 2001, Muñoz, Llanes 2014. An apparent-time study was imple- mented in order to test whether a change in learner setting (i.e. limited exposure to the target language vs. abundant exposure shows any evidence which can be explained by such external factors. Data was elicited from the speech samples of 97 speakers of L1 Estonian and L1 interference effects were analysed sound by sound. The results show that the younger generation displays less L1 Estonian interference than the older generation. Both greater exposure to the target language and earlier age of L2 learning onset correlate with the ability to produce more sounds target-like.

  6. An epidemiological perspective of personalized medicine: the Estonian experience

    OpenAIRE

    Milani, L.; Leitsalu, L; Metspalu, A

    2015-01-01

    Milani L, Leitsalu L, Metspalu A (University of Tartu). An epidemiological perspective of personalized medicine: the Estonian experience (Review). J Intern Med 2015; 277: 188?200. The Estonian Biobank and several other biobanks established over a decade ago are now starting to yield valuable longitudinal follow-up data for large numbers of individuals. These samples have been used in hundreds of different genome-wide association studies, resulting in the identification of reliable disease-ass...

  7. How Tests Change Teaching: A Model for Reference

    Science.gov (United States)

    Shih, Chih-Min

    2009-01-01

    The purpose of this study was to investigate the washback effects of the General English Proficiency Test (GEPT) on English teaching in two applied foreign language departments in Taiwan. One had prescribed its GEPT requirement to its day-division students whereas the other had not. Overall, the GEPT did not induce a high level of washback on…

  8. Thyroid function tests in the reference range and fracture

    DEFF Research Database (Denmark)

    Aubert, Carole E.; Floriani, Carmen; Bauer, Douglas C.

    2017-01-01

    -vertebral, and vertebral fractures. Results were presented as hazard ratios (HR) with 95% confidence interval (CI) adjusted for age and sex. For clinical relevance, we studied TSH according to five categories: 0.45-0.99mIU/L; 1.00-1.49mIU/L; 1.50-2.49mIU/L; 2.50-3.49mIU/L; 3.50-4.49mIU/L (reference). FT4 was assessed......, 1.19 (1.01-1.41) for TSH 1.00-1.49mIU/L, 1.09 (0.93-1.28) for TSH 1.50-2.49mIU/L, and 1.12 (0.94-1.33) for TSH 2.50-3.49mIU/L (P for trend = 0.004). Hip fracture was also associated with FT4 (HR [95%CI] 1.22 [1.11-1.35] per one standard deviation increase in FT4). FT4 only was associated with any...... as study-specific standard deviation increase, because assays varied between cohorts. Results: During 659,059 person-years, 2,565/56,835 participants had hip fracture (4.5%; 12 studies with data on hip fracture). The pooled adjusted HR (95% CI) for hip fracture was 1.25 (1.05-1.49) for TSH 0.45-0.99mIU/L...

  9. External Macroeconomic Shocks and the Estonian economy: How did the Russian Financial Crisis affect Estonian Unemployment and Foreign Trade?

    OpenAIRE

    Raul Eamets; Urmas Varblane; Kaja Sostra

    2003-01-01

    In this empirical paper we examine how the Russian financial crisis affected Estonian unemployment and foreign trade. In our interpretation the Russian crisis caused depression in the Estonian economy, but at the same time it also caused a relatively fast reallocation of trade. Eastward export flows (largely foodstuffs) declined drastically while exports to Finland and Sweden largely increased. Several manufacturing firms went into bankruptcy and foreign investors benefited from relatively lo...

  10. Avoidable mortality in Estonia: exploring the differences in life expectancy between Estonians and non-Estonians in 2005-2007.

    Science.gov (United States)

    Baburin, A; Lai, T; Leinsalu, M

    2011-11-01

    A considerable increase in social inequalities in mortality was observed in Eastern Europe during the post-communist transition. This study evaluated the contribution of avoidable causes of death to the difference in life expectancy between Estonians and non-Estonians in Estonia. Descriptive study. Temporary life expectancy (TLE) was calculated for Estonian and non-Estonian men and women aged 0-74 years in 2005-2007. The ethnic TLE gap was decomposed by age and cause of death (classified as preventable or treatable). The TLE of non-Estonian men was 3.53 years less than that of Estonian men, and the TLE of non-Estonian women was 1.36 years less than that of Estonian women. Preventable causes of death contributed 2.19 years to the gap for men and 0.78 years to the gap for women, while treatable causes contributed 0.67 and 0.33 years, respectively. Cardiorespiratory conditions were the major treatable causes of death, with ischaemic heart disease alone contributing 0.29 and 0.08 years to the gap for men and women, respectively. Conditions related to alcohol and substance use represented the largest proportion of preventable causes of death. Inequalities in health behaviours underlie the ethnic TLE gap in Estonia, rather than inequalities in access to health care or the quality of health care. Public health interventions should prioritize primary prevention aimed at alcohol and substance use, and should be implemented in conjunction with wider social policy measures. Copyright © 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  11. Estonian Airi Boeing sattus kaks korda hädaolukorda / Krister Kivi

    Index Scriptorium Estoniae

    Kivi, Krister, 1975-

    2011-01-01

    Estonian Airi Boeing ES-ABL sattus 2011. aasta algus kahel korral ohtlikku olukorda. Lennuamet tegi Estonian Airile ettekirjutuse, kuid seda pole ameti kodulehel avaldatud. Lennufirma kapteni ja lennuohutuse inspektori Andreas Kari, lennuameti selgitusi

  12. Acquisition of compounds in Estonian and Russian: Frequency, productivity, transparency and simplicity effect

    National Research Council Canada - National Science Library

    Reili Argus; Victoria Kazakovskaya

    2013-01-01

    ... – Estonian and Russian. Longitudinal data on three Russian and two Estonian typically-developing monolingual children and their caregivers was analysed and compared in relation to first emergence, the development...

  13. Estonian Air valmistub odavate piletitega EasyJeti tulekuks / Erkki Erilaid

    Index Scriptorium Estoniae

    Erilaid, Erkki

    2004-01-01

    Estonian Air pidi langetama piletihindu Berliini ja Londoni liinil kolmandiku võrra, kuna oktoobri lõpust hakkab Tallinna lennujaamast reise tegema uus odavlennufirma Easy-Jet. Lisa: Estonian Airi hinnad internetis

  14. Client-centeredness of Finnish and Estonian nursing students and the support from nursing education to develop it. Students' self-evaluation.

    Science.gov (United States)

    Kalam-Salminen, Ly; Valkonen, Marjo-Riitta; Aro, Ilme; Routasalo, Pirkko

    2013-10-01

    The purpose of this comparative study is to describe the differences between Finnish and Estonian students evaluations about their client-centeredness and educational support they received to develop it. Client-centeredness has many positive effects on the quality and effectiveness of care. However, some deficiencies have been identified in the client-centeredness of nursing staff. Research on the subject has been limited, and we lack knowledge of graduating students' competence in client-centeredness and the support of their education to develop it. The sample consisted of 390 undergraduate nursing students, 195 from Finland and 195 from Estonia. The data were collected in 2009 using the structured five-point scale questionnaire. The questionnaire was designed to measure students' client-centeredness and the educational support they received from nursing education. The data were analyzed by the PASW Statistics 18-programme using descriptive statistics, Kolmogorov-Smirnov test and Mann-Whitney U-test. Predominantly, students in both countries evaluated their level of client-centeredness high. The Estonian students generally evaluated their client-centeredness higher compared to the Finnish students. The same applied to support provided by nursing education. The greatest differences were related to education and particularly theoretical teaching. In Estonia, students' client-centeredness manifested itself more in politeness and willingness to serve clients, whereas respecting the clients' values was emphasized in Finland. Students' requisites, referred here as knowledge, skills and abilities to implement client-centered nursing, for client-centeredness had deficiencies, and the support from education was also the weakest regarding these aspects. In future, education on development of nursing activities, acquisition of knowledge and services provided by health care as well as legislation should be enhanced, since these areas proved the most difficult for the students

  15. Microsatellite, blood group and transferrin protein diversity of Estonian dairy cattle breeds

    Directory of Open Access Journals (Sweden)

    S. VÄRV

    2008-12-01

    Full Text Available This study investigates genetic diversity within and among three Estonian dairy cattle breeds (Estonian Native, Estonian Red and Estonian Holstein. A total of 36 markers (25 microsatellites, 10 blood group systems and transferrin protein were investigated and the within-breed diversity was quantified by expected heterozygosity, number of private alleles and mean allelic richness. The population structure was studied by computing the inbreeding coefficients, breed differentiation and relationships were investigated with random drift-based measures and a factorial correspondence analysis. In addition, a neighbour-joining tree was drawn summarising allele sharing distances for 195 individuals of the Estonian breeds, Western Finncattle, and Danish Jersey. The Estonian breeds displayed generally similar levels of within-population diversity. Depending on the set of markers used 6.2 or 4.3% of the total genetic variation can be explained by differences among the breeds. Construction of the tree for individuals revealed a distinctive pattern of grouping for Estonian Holstein, Estonian Red and Danish Jersey, but Estonian Native and Western Finncattle appeared on the same branches. This indicates that the gene pool of Estonian Native largely overlaps with that of Western Finncattle. However, our genetic marker analysis shows that the three Estonian breeds are genetically differentiated, suggesting that the current gene pool of Estonian dairy cattle is diverse.;

  16. Adapting the Survey of Attitudes towards Statistics (SATS-36) for Estonian Secondary School Students

    Science.gov (United States)

    Hommik, Carita; Luik, Piret

    2017-01-01

    The purpose of this study is to adapt the Survey of Attitudes Towards Statistics (SATS-36) for Estonian secondary school students in order to develop a valid instrument to measure students' attitudes within the Estonian educational context. The SATS-36 was administered to Estonian-speaking secondary school students before their compulsory…

  17. Joakim Helenius: Estonian Air võtku eeskuju airBalticust / Siim Sultson

    Index Scriptorium Estoniae

    Sultson, Siim

    2010-01-01

    Estonian Airi ühe võimaliku nõukogu esimehe Jaokim Heleniuse hinnangul on väikeste lennufirmade, nagu Estonian Air ja airBaltic jaoks päris palju tegutsemisruumi. Estonian Airil tuleb leida oma nišš ja kindel, kuid omanäoline strateegia

  18. SAS tahab Estonian Airi liita lätlaste firmaga airBaltic / Andres Eilart

    Index Scriptorium Estoniae

    Eilart, Andres

    2007-01-01

    SAS plaanib Estonian Airi ja Läti firma airBalticu liitmisega luua uue lennufirma. Autori hinnangul viitavad Estonian Airi laienemisplaanidele kriipsu peale tõmbamine ja SAS-i investeeringud airBalticusse sellele, et ühendamise käigus "neelab" Läti firma Estonian Airi

  19. How to deal with double partial verification when evaluating two index tests in relation to a reference test?

    NARCIS (Netherlands)

    van Geloven, Nan; Brooze, Kimiko A.; Opmeer, Brent C.; Mol, Ben Willem; Zwinderman, Aeilko H.

    2012-01-01

    Research into the diagnostic accuracy of clinical tests is often hampered by single or double partial verification mechanisms, that is, not all patients have their disease status verified by a reference test, neither do all patients receive all tests under evaluation (index tests). We show methods

  20. Results of the LIRES Round Robin test on high temperature reference electrodes for LWR applications

    Energy Technology Data Exchange (ETDEWEB)

    Bosch, R.W. [SCK.CEN, Nuclear Research Centre Belgium, Boeretang 200, B-2400 Mol (Belgium); Nagy, G. [Magyar Tudomanyos Akademia KFKI Atomenergia Kutatointezet, AEKI, Konkoly Thege ut 29-33, 1121 Budapest (Hungary); Feron, D. [CEA Saclay, 91191 Gif-Sur-Yvette Cedex (France); Navas, M. [CIEMAT, Edificio 30, Dpto. Fision Nuclear, Avda. Complutense 22, 28040 Madrid, (Spain); Bogaerts, W. [KU Leuven, Kasteelpark Arenberg 31, B-3001 Leuven (Belgium); Karnik, D. [Nuclear Research Institute, NRI, Rez (Czech Republic); Dorsch, T. [Framatone ANP, Inc., Charlotte, North Carolina (United States); Molander, A. [Studsvik AB SE-611 82 Nykoeping (Sweden); Maekelae, K. [Materials and Structural Integrity, VTT Technical Research Centre of Finland, Kemistintie 3, P.O. Box 1704, FIN-02044 VTT (Finland)

    2004-07-01

    A European sponsored research project has been started on 1 October 2000 to develop high temperature reference electrodes that can be used for in-core electrochemical measurements in Light Water Reactors (LWR's). This LIRES-project (Development of Light Water Reactor Reference Electrodes) consists of 9 partners (SCK-CEN, AEKI, CEA, CIEMAT, KU Leuven, NRI Rez, Framatone ANP, Studsvik Nuclear and VTT) and will last for four years. The main objective of this LIRES project is to develop a reference electrode, which is robust enough to be used inside a LWR. Emphasize is put on the radiation hardness of both the mechanical design of the electrode as the proper functioning of the electrode. A four steps development trajectory is foreseen: (1) To set a testing standard for a Round Robin, (2) To develop different reference electrodes, (3) To perform a Round Robin test of these reference electrodes followed by selection of the best reference electrode(s), (4) To perform irradiation tests under appropriate LWR conditions in a Material Test Reactor (MTR). Four different high temperature reference electrodes have been developed and are being tested in a Round Robin test. These electrodes are: A Ceramic Membrane Electrode (CME), a Rhodium electrode, an external Ag/AgCl electrode and a Palladium electrode. The presentation will focus on the results obtained with the Round Robin test. (authors)

  1. Reference module selection criteria for accurate testing of photovoltaic (PV) panels

    Energy Technology Data Exchange (ETDEWEB)

    Roy, J.N.; Gariki, Govardhan Rao; Nagalakhsmi, V. [Solar Semiconductor Pvt. Ltd., Banjara Hills, Hyderabad (India)

    2010-01-15

    It is shown that for accurate testing of PV panels the correct selection of reference modules is important. A detailed description of the test methodology is given. Three different types of reference modules, having different I{sub SC} (short circuit current) and power (in Wp) have been used for this study. These reference modules have been calibrated from NREL. It has been found that for accurate testing, both I{sub SC} and power of the reference module must be either similar or exceed to that of modules under test. In case corresponding values of the test modules are less than a particular limit, the measurements may not be accurate. The experimental results obtained have been modeled by using simple equivalent circuit model and associated I-V equations. (author)

  2. Estonian Airi president : uus äristrateegia toob ettevõttele edu / Borge Thornbech ; interv. Andres Reimer

    Index Scriptorium Estoniae

    Thornbech, Borge

    2007-01-01

    Estonian Air asutas regionaalsete lendude korraldamiseks ettevõtte Estonian Air Regional, idee on arendada tegevust lühidistantsidel ja luua ühenduslüli lennukompanii Euroopa-liinide vahel. Kommenteerivad Olev Schults, Oleg Harlamov, Rein Mark. Vt. samas: Kõik aktsionärid vannuvad Estonian Airile truudust; Estonian Air kaalub Tartu lennuliini avamist. Kaart: Reisijate jagunemine sihtkohtade vahel. Graafikud: Estonian Air kukkus kahjumisse

  3. Building Energy Simulation Test for Existing Homes (BESTEST-EX): Instructions for Implementing the Test Procedure, Calibration Test Reference Results, and Example Acceptance-Range Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Judkoff, R.; Polly, B.; Bianchi, M.; Neymark, J.; Kennedy, M.

    2011-08-01

    This publication summarizes building energy simulation test for existing homes (BESTEST-EX): instructions for implementing the test procedure, calibration tests reference results, and example acceptance-range criteria.

  4. Field trial on glucose-induced insulin and metabolite responses in Estonian Holstein and Estonian Red dairy cows in two herds

    Directory of Open Access Journals (Sweden)

    Kaart Tanel

    2010-01-01

    Full Text Available Abstract Background Insulin secretion and tissue sensitivity to insulin is considered to be one of the factors controlling lipid metabolism post partum. The objective of this study was to compare glucose-induced blood insulin and metabolite responses in Estonian Holstein (EH, n = 14 and Estonian Red (ER, n = 14 cows. Methods The study was carried out using the glucose tolerance test (GTT performed at 31 ± 1.9 days post partum during negative energy balance. Blood samples were obtained at -15, -5, 5, 10, 20, 30, 40, 50 and 60 min relative to infusion of 0.15 g/kg BW glucose and analysed for glucose, insulin, triglycerides (TG, non-esterified fatty acids (NEFA, cholesterol and β-hydroxybutyrate (BHB. Applying the MIXED Procedure with the SAS System the basal concentration of cholesterol, and basal concentration and concentrations at post-infusion time points for other metabolites, area under the curve (AUC for glucose and insulin, clearance rate (CR for glucose, and maximum increase from basal concentration for glucose and insulin were compared between breeds. Results There was a breed effect on blood NEFA (P P P P P P th min nadir (P th min postinfusion (P Conclusion Our results imply that glucose-induced changes in insulin concentration and metabolite responses to insulin differ between EH and ER dairy cows.

  5. Clinical experience of a new reference material for exercise capacity in exercise stress testing in Sweden.

    Science.gov (United States)

    Lindow, Thomas; Mosén, Henrik; Engblom, Henrik

    2017-09-21

    In 2014, the Swedish Association of Clinical Physiology recommended the use of a new reference material for exercise capacity in bicycle exercise stress testing, 'the Kalmar material'. Compared to the formerly used reference material, 'the Kristianstad material', an increase in the amount of patients being classified as having decreased exercise capacity was expected, but the extent of this in clinical practice is not known. Results of exercise capacity from 1449 bicycle exercise tests, in patients aged ≥20 years (656 women, 793 men) performed at two departments of Clinical Physiology before and after change of reference materials, were collected. Maximal workload was related to the predicted values of both reference materials. If made, recommendations for supplemental nuclear myocardial perfusion imaging study by the attending physician were noted. Using the new reference material, 31% of all patients were classified as having a decreased exercise capacity, compared to 17% using the formerly used reference material. The difference between the two reference materials was largest in the older age groups. In one of the departments, an increase in recommendations of supplemental myocardial perfusion studies was seen after introduction of the new reference material, whereas the opposite was seen at the other department. A large amount of patients are being classified as having decreased exercise capacity and very few as having good exercise capacity using the new reference material for exercise capacity. © 2017 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  6. Anodonta imbecillis copper sulfate reference toxicant test, Clinch River - Environmental Restoration Program (CR-ERP)

    Energy Technology Data Exchange (ETDEWEB)

    Simbeck, D.J.

    1997-06-01

    Reference toxicant testing using juvenile freshwater mussels was conducted as part of the CR-ERP biomonitoring study of Clinch River sediments to assess the sensitivity of test organisms and the overall performance of the test. Tests were conducted using moderately hard synthetic water spiked with known concentrations of copper as copper sulfate. Toxicity testing of copper sulfate reference toxicant was conducted from May 12-21, 1993. The organisms used for testing were juvenile fresh-water mussels (Anodonta imbecillis). Results from this test showed an LC{sub 50} value of 1.12 mg Cu/L which is lower than the value of 2.02 mg Cu/L obtained in a previous test. Too few tests have been conducted with copper as the toxicant to determine a normal range of values.

  7. An empirical test of reference price theories using a semiparametric approach

    DEFF Research Database (Denmark)

    Boztug, Yasemin; Hildebrandt, Lutz

      In this paper we estimate and empirically test different behavioral theories of consumer reference price formation. Two major theories are proposed to model the reference price reaction: assimilation contrast theory and prospect theory. We assume that different consumer segments will use...... different reference prices. The study builds on earlier research by Kalyanaram and Little (1994); however, in contrast to their work, we use parametric and semiparametric approaches to detect the structure of the underlying data sets. The different models are tested using a program module in GAUSS...

  8. A field study of frame-of-reference effects on personality test validity.

    Science.gov (United States)

    Hunthausen, John M; Truxillo, Donald M; Bauer, Talya N; Hammer, Leslie B

    2003-06-01

    As part of a test validation study at a major U.S.-based airline, the authors tested the effects of providing an "at work" frame-of-reference on the validity of the NEO Five-Factor Inventory among a sample of customer service supervisors (N = 206). Frame-of-reference moderated the validity of the Extraversion and Openness to Experience subscales after controlling for cognitive ability. In addition, the frame-of-reference personality test showed incremental validity over cognitive ability (deltaR2 = .16), but the standard personality test did not (deltaR2 = .05). The authors' discussion focuses on implications for personality theory and research and on implications for increasing the validity of personality tests in organizational settings.

  9. Trends in smoking behaviour among Estonian physicians in 1982-2014.

    Science.gov (United States)

    Pärna, Kersti; Põld, Mariliis; Ringmets, Inge

    2017-07-25

    Smoking surveys among physicians have proved useful in highlighting the importance of physicians as healthy life style exemplars and role models in tobacco control and smoking cessation. The aim of this study was to give an overview of smoking behaviour among Estonian physicians from 1982 to 2014. Three cross-sectional postal surveys using a self-administered questionnaire were carried out among all practising physicians in Estonia. The number of physicians participating in this study was 3786 in 1982, 2735 in 2002, and 2902 in 2014. Data analysis involved calculating the age-standardized prevalences of smoking, prevalences of smoking by age group and mean age of smoking initiation. A non-parametric test for trend was used to assess significant changes in smoking over time. Age-standardized prevalence of current smoking among men was 39.7% in 1982, 20.9% in 2002, and 14.3% in 2014 and among women 12.2%, 8.0%, and 5.2%, respectively (p smoking among men and women was in age groups under 35 (from 55.2% to 16.7% and from 16.7% to 2.8%, respectively) and 35-44 (from 47.1% to 8.3% and from 19.5% to 5.1%, respectively) (p smoking initiation decreased from 20.4 to 19.3 among men and from 24.5 to 20.4 among women over the study period. In 1982-2014, smoking prevalence among Estonian physicians declined substantially. This may influence the willingness of society to recognize the health consequences of smoking which could give a support to the decline of the smoking epidemic in the country. Differences between smoking among male and female physicians persisted over the study period, but mean age of smoking initiation decreased. A further decline in smoking among Estonian physicians should be encouraged by special efforts targeted at physicians.

  10. Proficiency test for gamma spectroscopic analysis with a simulated fission product reference spectrum.

    Science.gov (United States)

    Karhu, P; De Geer, L-E; McWilliams, E; Plenteda, R; Werzi, R

    2006-01-01

    Within the proficiency test programme for the radionuclide laboratories supporting the verification of the Comprehensive Nuclear-Test-Ban Treaty, a simulated gamma spectrum with the characteristics of an atmospheric nuclear test was used as reference material. The spectrum was produced by the MCNP-based Virtual Gamma Spectroscopy Laboratory (VGSL), using analysis results of a historical measurement of nuclear weapons debris as input. The method was found suitable for a proficiency test assessing laboratories' gamma spectroscopic analysis.

  11. Improved imputation accuracy of rare and low-frequency variants using population-specific high-coverage WGS-based imputation reference panel.

    Science.gov (United States)

    Mitt, Mario; Kals, Mart; Pärn, Kalle; Gabriel, Stacey B; Lander, Eric S; Palotie, Aarno; Ripatti, Samuli; Morris, Andrew P; Metspalu, Andres; Esko, Tõnu; Mägi, Reedik; Palta, Priit

    2017-06-01

    Genetic imputation is a cost-efficient way to improve the power and resolution of genome-wide association (GWA) studies. Current publicly accessible imputation reference panels accurately predict genotypes for common variants with minor allele frequency (MAF)≥5% and low-frequency variants (0.5≤MAFWGS) based reference panel, comprising of 2244 Estonian individuals (0.25% of adult Estonians). Although the Estonian-specific panel contains fewer haplotypes and variants, the imputation confidence and accuracy of imputed low-frequency and rare variants was significantly higher. The results indicate the utility of population-specific reference panels for human genetic studies.

  12. Reference value for the 6-minute walk test in children and adolescents : a systematic review

    NARCIS (Netherlands)

    Mylius, C. F.; Paap, D.; Takken, T.

    2016-01-01

    Introduction: The 6-minute walk test is a submaximal exercise test used to quantify the functional exercise capacity in clinical populations. It measures the distance walked within a period of 6-minutes. Obtaining reference values in the pediatric population is especially demanding due to factors as

  13. Estonian Golf & Country Club / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2005-01-01

    Estonian Golf & Country Club'i etnomodernistlik golfikeskus ja klubihoone Jõelähtmel. Projekteerija: Arhitektuuristuudio Siim & Kreis. Autor Andres Siim. Konstruktor: Resand. Sisekujundaja Juta Lember (SAB Lember & Padar). Projekt 2004, valmis 2005. Ill.: I ja II korruse plaan, 3 värv. välis ja 3 sisevaadet

  14. Estonian Preschool Teachers' Views on Learning in Preschool

    Science.gov (United States)

    Ugaste, Aino; Tuul, Maire; Niglas, Katrin; Neudorf, Evelyn

    2014-01-01

    As in many Western countries, children's learning in the curriculum of Estonian Early Childhood Education is seen as a lifelong process, wherein the teacher is primarily a guide to children's active learning. Thus, a child-centred approach to learning is valued in the national curriculum, but our interest was whether this approach is fixed in the…

  15. Trace metal emissions from the Estonian oil shale fired power

    DEFF Research Database (Denmark)

    Aunela-Tapola, Leena A.; Frandsen, Flemming; Häsänen, Erkki K.

    1998-01-01

    Emission levels of selected trace metals from the Estonian oil shale fired power plant were studied. The plant is the largest single power plant in Estonia with an electricity production capacity of 1170 MWe (1995). Trace metals were sampled from the flue gases by a manual method incorporating...

  16. Estonian Golf & Country Clubi klubihoone / Andres Siim, Alar Just

    Index Scriptorium Estoniae

    Siim, Andres

    2005-01-01

    Harjumaal Jõelähtme vallas rajab Estonian Golf & Country Club uut Jägala-Jõesuu spordi- ja puhkekeskust, mille südameks saab puidust golgiklubi hoone, mida tutvustavad klubihoone arhitekt ja üks inseneridest. Ill.: vaade ehitusele, projekti kaks vaadet, lõige

  17. Top 10 Estonian albums of 2004 / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2004-01-01

    Heliplaatidest: Arvo Pärt "Pro et contra", Various composers "Baltic Voices 2", Raimo Kangro "Displays", Toivo Tulev "Be Lost in the Call", Indrek Vau and Mati Mikalai "Estonian Trumpet Music", Erdmann/Sooäär "Dessert Time, Peer Gynt & Other Stories", Alo Mattiisen "50 parimat laulu", Riho Sibul "Must", Rein Rannap "Tantsib klaveril", Eesti Keeled "Kella tiksumist..."

  18. Red in Estonian popular belief and folk costume

    Science.gov (United States)

    Barrett, S.; Roper, J.

    2006-06-01

    A visit by one of the authors to Estonia, and the discovery that the term 'red' was used locally for the colour 'orange', led to a detailed study of the colour red in Estonian belief and culture. The study is reported here, together with an interpretation of the red/orange substitution based on Berlin and Kay's model of colour term development in language.

  19. Value Education in Estonian Preschool Child Care Institutions

    Science.gov (United States)

    Ülavere, Pärje; Tammik, Anu

    2017-01-01

    For systematic implementation of value education in educational institutions, the national programme "Values Development in Estonian Society 2009-2013" (Ministry of Education and Research 2009) was prepared in Estonia. However, it was launched only in 2010, and the authors intended to ascertain the values of the heads of preschool child…

  20. Organizational Commitment in Estonian University Libraries: A Review and Survey

    Science.gov (United States)

    Kont, Kate-Riin; Jantson, Signe

    2014-01-01

    The data used in this article is based on the reviewing of relevant literature to provide an overview of the concepts of organizational commitment, job security, and interpersonal relations, as well as on the results of the original online survey, conducted by the article's authors, held in 2012 in Estonian university libraries governed by public…

  1. Sources of Individual Variation in Estonian Toddlers' Expressive Vocabulary

    Science.gov (United States)

    Urm, Ada; Tulviste, Tiia

    2016-01-01

    The vocabulary size of 16- to 30-month-old children (N = 1235) was assessed using the Estonian adaptation of the MacArthur-Bates Communicative Development Inventory: Words and Sentences (ECDI-II). The relationship between children's expressive vocabulary size and different factors of the child and his/her social environment was examined. Results…

  2. Parasiitluse viljad: Estonian Air ja Eesti riik / Mikk Salu

    Index Scriptorium Estoniae

    Salu, Mikk, 1975-

    2009-01-01

    Autori hinnangul oli Estonian Airi erastamise puhul tegemist ratsionaalse, kuid parasiitliku lähenemisega kasu teenimise eesmärgil, samuti oli riigipoolne viga läbimõtlematu suhtumine riigile kuuluvasse Tallinna lennujaama, samas on aga lennuühendus Eesti kui Euroopa nurgas asuva väikeriigi jaoks strateegiliselt oluline

  3. Kas Bombardier lennutab Estonian Airi üles? / Henrik Ilves

    Index Scriptorium Estoniae

    Ilves, Henrik

    2011-01-01

    Estonian Air on saanud oma käsutusse kaks kolmest ostetud lennukist Bombardier CRJ900, millega saavutatakse Boeing 737-ga võrreldes oluline kütuse kokkuhoid. 20 aastaga on müüdud CRJ-seeria lennukeid juba üle 1700

  4. A Sediment Testing Reference Area Database for the San Francisco Deep Ocean Disposal Site (SF-DODS)

    Science.gov (United States)

    EPA established and maintains a SF-DODS reference area database of previously-collected sediment test data. Several sets of sediment test data have been successfully collected from the SF-DODS reference area.

  5. Pharmacopoieal quality of non-expired and expired nifedipine formulations from Estonian and Russian Federation medicinal products market.

    Science.gov (United States)

    Teder, Kersti; Pepeloshev, Andrei; Matto, Vallo; Meos, Andres

    2013-01-01

    The pharmacopoeial quality of non-expired and expired nifedipine tablets of the same batches purchased from the Estonian and Russian Federation medicinal product markets was evaluated. The IR spectroscopy, HPLC analysis for quantitative content and purity of the active pharmaceutical ingredient (API), and dissolution test techniques were applied. In the experiments with non-expired nifedipine tablets, in all Estonian (n = 8, label claims 10, 20, and 40 mg) and Russian Federation (n = 4, label claim 10 mg) registered formulations the API was identified and quantified as nifedipine in amounts set by the European Pharmacopoeia and without exceeding the tolerance limits for the impurities. The dissolution rate was variable but all 10 and 20 mg non-expired nifedipine tablets released at least 80% of API in 12 h. The expiration of the nifedipine tablets led to somewhat increased dissolution rate while only traces of the nifedipine degradation products were discovered in the dissolution medium. In conclusion, our present study shows that with minor variations the Estonian and Russian Federation registered nifedipine tablets are comparable, the API preserves well beyond the expiration date but the expired nifedipine tablets may release the API faster than the non-expired tablets.

  6. Termite-Susceptible Species of Wood for Inclusion as a Reference in Indonesian Standardized Laboratory Testing.

    Science.gov (United States)

    Arinana; Tsunoda, Kunio; Herliyana, Elis N; Hadi, Yusuf S

    2012-03-28

    Standardized laboratory testing of wood and wood-based products against subterranean termites in Indonesia (SNI 01.7207-2006) (SNI) has no requirement for the inclusion of a comparative reference species of wood (reference control). This is considered a weakness of the Indonesian standard. Consequently, a study was undertaken to identify a suitable Indonesian species of community wood that could be used as a reference control. Four candidate species of community woods: Acacia mangium, Hevea brasiliensis, Paraserianthes falcataria and Pinus merkusii were selected for testing their susceptibility to feeding by Coptotermes formosanus. Two testing methods (SNI and the Japanese standard method JIS K 1571-2004) were used to compare the susceptibility of each species of wood. Included in the study was Cryptomeria japonica, the reference control specified in the Japanese standard. The results of the study indicated that P. merkusii is a suitable reference species of wood for inclusion in laboratory tests against subterranean termites, conducted in accordance with the Indonesian standard (SNI 01.7207-2006).

  7. Reference Pricing, Consumer Cost-Sharing, and Insurer Spending for Advanced Imaging Tests.

    Science.gov (United States)

    Robinson, James C; Whaley, Christopher; Brown, Timothy T

    2016-12-01

    Fees charged for similar imaging tests often vary dramatically within the same market, leading to wide variation in insurer spending and consumer cost-sharing. Reference pricing is an insurance design that offers good coverage to patients up to a defined contribution limit but requires the patients who select high-priced facilities to pay the remainder out of pocket. To measure the association between implementation of reference pricing and patient choice of facility, test prices, out-of-pocket spending, and insurer spending for advanced imaging (CT and MRI) procedures. Difference-in-differences multivariable analysis of insurance claims data. Study included 4751 employees of a national grocery chain (treatment group) and 23,428 enrollees in the nation's largest private insurance plan (comparison group) that used CT or MRI tests between 2010 and 2013. Patient choice of facility, price paid per test, patient out-of-pocket cost-sharing, and employer spending. Compared with trends in prices paid by insurance enrollees not subject to reference pricing, and after adjusting for characteristics of tests and patients, implementation of reference pricing was associated with a 12.5% (95% CI, -25.0%, 2.1%) reduction in average price paid per test by the end of the second full year of the program for CT scans and a 10.5% (95% CI, -16.9%, 3.6%) for MRIs. Out-of-pocket cost-sharing by patients declined by $71,508 (13.8%). The savings accruing to employees amounted to 45.5% of total savings from reference pricing, with the remainder accruing to the employer. Implementation of reference pricing led to reductions in payments by both employer and employees.

  8. [Routine laboratory tests unnecessary for children referred for recurrent wheezing and/or asthma].

    Science.gov (United States)

    de Vries, T W; Wormmeester, L; van Pinxteren-Nagler, E; Bakker, A J; Brand, P L

    2000-10-28

    To investigate the usefulness of laboratory testing and thorax radiography in children, referred to the paediatrician for evaluation of recurrent wheezing. Retrospective. In this study, 158 children referred for recurrent wheezing to a specialized child outpatient clinic of the Medisch Centrum Leeuwarden, the Netherlands, in the period 1 January 1994-31 December 1996, were evaluated according to a routine protocol including haemoglobin, ESR, leucocytes, immunoglobulins, sweat chloride levels and allergy testing and chest roentgenograms. It was determined whether these investigations had yielded abnormal results and whether these test results aided in confirming/rejecting the diagnosis of asthma or were helpful in clinical management. In 144 of the 158 (91%) children the diagnosis 'asthma' or 'recurrent wheezing' was made. Although numerous test results were abnormal they were not helpful in establishing the diagnosis. In only one child an abnormal chest radiograph was helpful (the radiograph showed infiltrative abnormalities). Tests for aero-allergy were rarely positive in children younger than 2 years; in children older than 6 years aero-allergy was found frequently, notably to dust mite (41/144). The results of this study suggest that--except for allergy testing--routine laboratory testing and chest roentgenograms are not indicated in children referred for evaluation of wheezing disorders. Aero-allergy testing may help to decide on preventive measures.

  9. Diffusion-controlled toluene reference material for VOC emissions testing: international interlaboratory study.

    Science.gov (United States)

    Howard-Reed, Cynthia; Liu, Zhe; Cox, Steven; Leber, Dennis; Samarov, Dan; Little, John C

    2014-04-01

    The measurement of volatile organic compound (VOC) emissions from building products and materials by manufacturers and testing laboratories, and the use of the test results for labeling programs, continue to expand. One issue that hinders wide acceptance for chamber product testing is the lack of a reference material to validate test chamber performance. To meet this need, the National Institute of Standards and Technology (NIST) and Virginia Tech (VT) have developed a prototype reference material that emits a single VOC similar to the emissions of a diffusion-controlled building product source with a dynamic emissions profile. The prototype material has undergone extensive testing at NIST and a pilot interlaboratory study (ILS) with four laboratories. The next development step is an evaluation of the prototype source in multiple-sized chambers of 14 laboratories in seven countries. Each laboratory was provided duplicate specimens and a test protocol. Study results identified significant issues related to the need to store the source at a subzero Celsius temperature until tested and possible inconsistencies in large chambers. For laboratories using a small chamber and meeting all the test method criteria, the results were very encouraging with relative standard deviations ranging from 5% to 10% across the laboratories. Currently, the chamber performance of laboratories conducting product VOC emissions testing is assessed through interlaboratory studies (ILS) using a source with an unknown emission rate. As a result, laboratory proficiency can only be based on the mean and standard deviation of emission rates measured by the participating ILS laboratories. A reference material with a known emission rate has the potential to provide an independent assessment of laboratory performance as well as improve the quality of interlaboratory studies. Several international laboratories with different chamber testing systems demonstrated the ability to measure the emission rate

  10. Reference values of mechanical and thermal pain tests in a pain-free population.

    Science.gov (United States)

    Neziri, Alban Y; Scaramozzino, Pasquale; Andersen, Ole K; Dickenson, Anthony H; Arendt-Nielsen, Lars; Curatolo, Michele

    2011-04-01

    Quantitative sensory tests are widely used in human research to evaluate the effect of analgesics and explore altered pain mechanisms, such as central sensitization. In order to apply these tests in clinical practice, knowledge of reference values is essential. The aim of this study was to determine the reference values of pain thresholds for mechanical and thermal stimuli, as well as withdrawal time for the cold pressor test in 300 pain-free subjects. Pain detection and pain tolerance thresholds to pressure, heat and cold were determined at three body sites: (1) lower back, (2) suprascapular region and (3) second toe (for pressure) or the lateral aspect of the leg (for heat and cold). The influences of gender, age, height, weight, body-mass index (BMI), body side of testing, depression, anxiety, catastrophizing and parameters of Short-Form 36 (SF-36) were analyzed by multiple regressions. Quantile regressions were performed to define the 5th, 10th and 25th percentiles as reference values for pain hypersensitivity and the 75th, 90th and 95th percentiles as reference values for pain hyposensitivity. Gender, age and/or the interaction of age with gender were the only variables that consistently affected the pain measures. Women were more pain sensitive than men. However, the influence of gender decreased with increasing age. In conclusion, normative values of parameters related to pressure, heat and cold pain stimuli were determined. Reference values have to be stratified by body region, gender and age. The determination of these reference values will now allow the clinical application of the tests for detecting abnormal pain reactions in individual patients. Copyright © 2010 European Federation of International Association for the Study of Pain Chapters. Published by Elsevier Ltd. All rights reserved.

  11. Factors Predicting Suicide among Russians in Estonia in Comparison with Estonians: A Case-Control Study

    Science.gov (United States)

    Kõlves, Kairi; Sisask, Merike; Anion, Liivia; Samm, Algi; Värnik, Airi

    2006-01-01

    Aim To explore differences between suicide victims among Russian immigrants in Estonia and native Estonians, according to socio-demographic background, substance use pattern, and recent life events to find out immigration-specific factors predicting suicide. Methods The psychological autopsy study included 427 people who committed suicide in 1999 and 427 randomly selected controls matched by region, gender, age, and nationality. Results The only variable that differed significantly between Russian and Estonian suicide cases was substance use pattern. Logistic regression models showed that factors associated with suicide for both nationalities were substance dependence and abuse (Russians: odds ratio [OR], 12.9; 95% confidence interval [95% CI], 4.2-39.2; Estonians: OR, 8.1; 95% CI, 3.9-16.4), economical inactivity Russians: OR 5.5; 95% CI, 1.3-22.9; Estonians: OR, 3.1; 95% CI, 1.3-7.1), and recent family discord (Russians: OR, 3.2; 95% CI, 1.1-9.9; Estonians: OR, 4.5; 95%, CI, 2.1-9.8). The variables that remained significant in the final model were having no partner (Estonians: OR, 3.0; 95% CI, 1.6-5.5), being unemployed (Estonians: OR, 5.5; 95% CI, 2.0-15.4), and being an abstainer (Estonians: OR, 6.7; 95% CI, 2.5-17.6) for Estonians, and somatic illness (Russians: OR, 4.1; 95% CI, 1.4-11.7), separation (Russians: OR, 32.3; 95% CI, 2.9-364.1), and death of a close person (Russians: OR, 0.2; 95% CI, 0.04-0.7) for Russians. Conclusion Although the predicting factors of suicide were similar among the Estonian Russians and Estonians, there were still some differences in the nature of recent life events. Higher suicide rate among Estonian Russians in 1999 could be at least partly attributable to their higher substance consumption. PMID:17171808

  12. Factors predicting suicide among Russians in Estonia in comparison with Estonians: case-control study.

    Science.gov (United States)

    Kolves, Kairi; Sisask, Merike; Anion, Liivia; Samm, Algi; Värnik, Airi

    2006-12-01

    To explore differences between suicide victims among Russian immigrants in Estonia and native Estonians, according to socio-demographic background, substance use pattern, and recent life events to find out immigration-specific factors predicting suicide. The psychological autopsy study included 427 people who committed suicide in 1999 and 427 randomly selected controls matched by region, gender, age, and nationality. The only variable that differed significantly between Russian and Estonian suicide cases was substance use pattern. Logistic regression models showed that factors associated with suicide for both nationalities were substance dependence and abuse (Russians: odds ratio [OR], 12.9; 95% confidence interval [95% CI], 4.2-39.2; Estonians: OR, 8.1; 95% CI, 3.9-16.4), economical inactivity (Russians: OR 5.5; 95% CI, 1.3-22.9; Estonians: OR, 3.1; 95% CI, 1.3-7.1), and recent family discord (Russians: OR, 3.2; 95% CI, 1.1-9.9; Estonians: OR, 4.5; 95%, CI, 2.1-9.8). The variables that remained significant in the final model were having no partner (Estonians: OR, 3.0; 95% CI, 1.6-5.5), being unemployed (Estonians: OR, 5.5; 95% CI, 2.0-15.4), and being an abstainer (Estonians: OR, 6.7; 95% CI, 2.5-17.6) for Estonians, and somatic illness (Russians: OR, 4.1; 95% CI, 1.4-11.7), separation (Russians: OR, 32.3; 95% CI, 2.9-364.1), and death of a close person (Russians: OR, 0.2; 95% CI, 0.04-0.7) for Russians. Although the predicting factors of suicide were similar among the Estonian Russians and Estonians, there were still some differences in the nature of recent life events. Higher suicide rate among Estonian Russians in 1999 could be at least partly attributable to their higher substance consumption.

  13. Distribution of charophyte species in Estonian coastal water (NE Baltic Sea

    Directory of Open Access Journals (Sweden)

    Kaire Torn

    2004-04-01

    Full Text Available Charophytes constitute a group of macrophytes that usually inhabit soft bottoms with shallow water. They occur mostly in fresh-water environments but can also be found in brackish waters. Due to their requirement for clear water they are considered sensitive to eutrophication and therefore often used as an indicator for good water quality. The diverse structure of the Estonian coastline with its numerous sheltered bays and shallow, soft-bottom archipelago areas coupled with low salinity conditions provides an excellent habitat for charophytes. To date, seven species have been described in Estonian coastal waters, NE Baltic Sea. Last systematic investigations on charophyte distribution date back 20-30 years. During the summer of 2001 the locations where charophytes have previously been found were revisited and new sites sampled, to describe the present distribution of quantitative and qualitative parameters of charophyte species. Sampling was performed mainly by SCUBA diving; occurrence, abundance and wet weight biomass were estimated for each location. Six species of charophytes were identified. Compared to previously recorded material, no significant changes in the distribution pattern of charophytes were found. The dependence of charophyte distribution on environmental settings was tested, with depth and substrate quality explaining most of the variability in distribution. Salinity within observed range had minor influence on charophytes.

  14. Association of Reference Pricing for Diagnostic Laboratory Testing With Changes in Patient Choices, Prices, and Total Spending for Diagnostic Tests.

    Science.gov (United States)

    Robinson, James C; Whaley, Christopher; Brown, Timothy T

    2016-09-01

    Prices for laboratory and other clinical services vary widely. Employers and insurers increasingly are adopting "reference pricing" policies to create incentives for patients to select lower-priced facilities. To measure the association between implementation of reference pricing and patient choice of laboratory, test prices, patient out-of-pocket spending, and insurer spending. We conducted an observational study of changes in laboratory pricing and selection by employees of a large national grocery firm (n = 30 415) before and after the firm implemented a reference pricing policy for laboratory services and compared the findings with changes over the same period for policy holders of a large national insurer that did not implement reference pricing (n = 181 831). The grocery firm established a maximum payment limit at the 60th percentile of the distribution of prices for each laboratory test in each region. Employees were provided with data on prices at all laboratories through a mobile digital platform. Patients selecting a laboratory that charged more than the payment limit were required to pay the full difference themselves. A total of 2.13 million claims were analyzed for 285 types of in vitro diagnostic tests between 2010 and 2013. Patient choice of laboratory, price paid per test, patient out-of-pocket costs, and employer spending. Compared with trends in prices paid by insurance policy holders not subject to reference pricing, and after adjusting for characteristics of tests and patients, implementation of reference pricing was associated with a 31.9% reduction (95% CI, 20.6%-41.6%) in average price paid per test by the third year of the program. In these 3 years, total spending on laboratory tests declined by $2.57 million (95% CI, $1.59-$3.35 million). Out-of-pocket costs by patients declined by $1.05 million (95% CI, $0.73-$1.37 million). Spending by the employer declined by $1.70 million (95% CI, $0.92-$2.48 million). When combined with

  15. Round-robin testing of a reference glass for low-activity waste forms

    Energy Technology Data Exchange (ETDEWEB)

    Ebert, W. L.; Wolf, S. F.

    1999-12-06

    A round robin test program was conducted with a glass that was developed for use as a standard test material for acceptance testing of low-activity waste glasses made with Hanford tank wastes. The glass is referred to as the low-activity test reference material (LRM). The program was conducted to measure the interlaboratory reproducibility of composition analysis and durability test results. Participants were allowed to select the methods used to analyze the glass composition. The durability tests closely followed the Product Consistency Test (PCT) Method A, except that tests were conducted at both 40 and 90 C and that parallel tests with a reference glass were not required. Samples of LRM glass that had been crushed, sieved, and washed to remove fines were provided to participants for tests and analyses. The reproducibility of both the composition and PCT results compare favorably with the results of interlaboratory studies conducted with other glasses. From the perspective of reproducibility of analysis results, this glass is acceptable for use as a composition standard for nonradioactive components of low-activity waste forms present at >0.1 elemental mass % and as a test standard for PCTS at 40 and 90 C. For PCT with LRM glass, the expected test results at the 95% confidence level are as follows: (1) at 40 C: pH = 9.86 {+-} 0.96; [B] = 2.30 {+-} 1.25 mg/L; [Na] = 19.7 {+-} 7.3 mg/L; [Si] = 13.7 {+-} 4.2 mg/L; and (2) at 90 C: pH = 10.92 {+-} 0.43; [B] = 26.7 {+-} 7.2 mg/L; [Na] = 160 {+-} 13 mg/L; [Si] = 82.0 {+-} 12.7 mg/L. These ranges can be used to evaluate the accuracy of PCTS conducted at other laboratories.

  16. Course of Skin Symptoms and Quality of Life in Children Referred for Patch Testing

    DEFF Research Database (Denmark)

    Simonsen, Anne B; Sommerlund, Mette; Deleuran, Mette

    2015-01-01

    for patch testing, a retrospective questionnaire was sent to children and adolescents referred for patch testing during a 9-year period. Persistent eczema at follow-up was strongly associated to atopic dermatitis, but was not explained by gender, age, contact allergy or time span from patch testing...... to follow-up. Among patients without atopic dermatitis, 23.5% reported to suffer from chronic eczema. Persistent eczema increased the risk of severe impairment of life quality. Our findings indicate a significant risk of childhood eczema becoming chronic and affecting life quality considerably. Patch......Children are patch tested in the same manner as adults, but little has been done to establish whether positive or negative findings influence the course of skin symptoms. To uncover the course of skin symptoms and the impact of persistent eczema on life quality in paediatric patients referred...

  17. [Pärtel Lippus. The acoustic features and perception of the Estonian quantity system] / Stefan Werner

    Index Scriptorium Estoniae

    Werner, Stefan

    2012-01-01

    Arvustus: Pärtel Lippus. The acoustic features and perception of the Estonian quantity system. Tartu : Tartu University Press, 2011. (Dissertationes philologiae estonicae Universitatis Tartuensis ; 29)

  18. CLUPEA HARENGUS MEMBRAS: ABOUT THE ETYMOLOGY OF A CERTAIN FISH NAME IN ESTONIAN, LATVIAN AND LIVONIAN

    Directory of Open Access Journals (Sweden)

    Udo Uibo

    2012-01-01

    Full Text Available In this article, the names of Clupea harengus membras will be considered in Estonian, (Salaca Livonian and Latvian (respectively räim, reńǵ and reņģe ‘Baltic herring’. It will be shown that the source of all of these words is the Estonian-Swedish strämg (sträηg, or its preceding word shape *sträimg. The Latvian reņģe is borrowed from Estonian-Swedish through Salaca Livonian. Paul Ariste proposed an adequate etymology for the Estonian räim as early as 1933.

  19. Antecedents of Academic Emotions: Testing the Internal/External Frame of Reference Model for Academic Enjoyment

    Science.gov (United States)

    Goetz, Thomas; Frenzel, Anne C.; Hall, Nathan C.; Pekrun, Reinhard

    2008-01-01

    The present study focused on students' academic enjoyment as predicted by achievement in multiple academic domains. Assumptions were based on Marsh's internal/external (I/E) frame of reference model and Pekrun's control-value theory of achievement emotions, and were tested in a sample of 1380 German students from grades 5 to 10. Students' academic…

  20. A Test and Reformulation of Reference Group and Role Correlates of Premarital Sexual Permissiveness Theory

    Science.gov (United States)

    Libby, Roger W.; And Others

    1978-01-01

    Propositions concerned with reference group and role correlates of Ira Reiss' premarital sexual permissiveness theory were tested. Reiss' basic propositions are only partially supported. Closeness to mother's sexual standards is considerably more predictive of self-permissiveness than was obvious in Reiss' theory. Closeness to friends' and peers'…

  1. EVALUATION OF ALTERNATIVE REFERENCE TOXICANTS FOR USE IN THE EARTHWORM TOXICITY TEST

    Science.gov (United States)

    The use of the 14-d earthworm toxicity test to aid in the evaluation of the ecological impact of contaminated soils is becoming increasingly widespread. However,the method is in need of further standardization. As part of this continuing process, the choice of reference toxicants...

  2. Proof of concept testing of a positive reference material for in vivo and in vitro skin irritation testing.

    Science.gov (United States)

    Nomura, Yusuke; Lee, Michelle; Fukui, Chie; Watanabe, Kayo; Olsen, Daniel; Turley, Audrey; Morishita, Yuki; Kawakami, Tsuyoshi; Yuba, Toshiyasu; Fujimaki, Hideo; Inoue, Kaoru; Yoshida, Midori; Ogawa, Kumiko; Haishima, Yuji

    2017-12-11

    In vivo and in vitro irritation testing is important for evaluating the biological safety of medical devices. Here, the performance of positive reference materials for skin irritation testing was evaluated. Four reference standards, referred to as Y-series materials, were analyzed: a polyvinyl chloride (PVC) sheet spiked with 0 (Y-1), 1.0 (Y-2), 1.5 (Y-3), or 10 (Y-4) parts of Genapol X-080 per 100 parts of PVC by weight. Y-1, Y-2, and Y-3 did not induce skin irritation responses in an in vitro reconstructed human epidermis (RhE) tissue model, as measured by tissue viability or interleukin-1α release, or in an in vivo intracutaneous response test using rabbits. In contrast, Y-4 extracts prepared with saline or sesame oil at 37°C and 50°C clearly elicited positive irritation responses, including reduced viability (< 50%) and significantly higher interleukin-1α release compared with the solvent alone group, in the RhE tissue model and an intracutaneous response test, where substantial necrosis was observed by histopathology. The positive skin irritation responses induced in vitro under various extraction conditions, as well as those elicited in vivo, indicate that Y-4 is an effective extractable positive control material for in vivo and in vitro skin irritation tests of medical devices. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2017. © 2017 Wiley Periodicals, Inc.

  3. Estonian Air püüdis viimase hetkeni Top Toursi päästa / Mirko Ojakivi

    Index Scriptorium Estoniae

    Ojakivi, Mirko

    2010-01-01

    Estonian Air kaalus Top Toursile appiminekut, sest reisifirma oli Estonian Airil üks olulisemaid koostööpartnereid. Abi oleks puudutanud ennekõike uutele lendudele allahindluse tegemist, räägiti ka võimalikust krediidist

  4. Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values.

    Science.gov (United States)

    van den Bosch, Gerbrich E; van Dijk, Monique; Tibboel, Dick; Valkenburg, Abraham J

    2017-03-16

    Quantitative sensory testing (QST) is often used to measure children's and adults' detection- and pain thresholds in a quantitative manner. In children especially the Thermal Sensory Analyzer (TSA-II) is often applied to determine thermal detection and pain thresholds. As comparisons between studies are hampered by the different testing protocols used, we aimed to present a standard protocol and reference values for thermal detection- and pain thresholds in children. Our standard testing protocol includes reaction time dependent and independent tests and takes about 14-18 min to complete. Reference values were obtained from a sample of 69 healthy term born children and adolescents with a median age of 11.2 years (range 8.2 to 17.9 years old). Seventy-one children were recruited and data of 28 males and 41 females was obtained correctly. We studied possible age and sex differences. This study provides Dutch reference values and presents a standard quantitative sensory testing protocol for children with an age from 8 years onwards. This protocol appeared to be feasible, since only two out of 71 participants were not able to correctly complete the protocol due to attention deficits and were therefore excluded. We found some significant age and sex differences: females were statistically significantly more sensitive for both cold and heat pain compared to males, and the youngest children (8-9 years old) were less sensitive to detect a warm stimulus. The youngest children tend to be more sensitive to heat pain in comparison to older participants, although the difference was not statistically significant. We present a feasible thermal quantitative sensory testing protocol for children and reference values that are easy to interpret and may serve as normative values for future studies.

  5. Eesti patsient. Haiguse ja haige inimese kujutamise mudel 19. sajandi eesti kultuuris ja kirjasõnas. The Estonian Patient: A Model for the Representation of Illness and the Ill in 19th Century Estonian Culture and Letters

    Directory of Open Access Journals (Sweden)

    Janek Kraavi

    2012-04-01

    Full Text Available The portrait of the 18th and 19th century „Estonian patient” sketched in this article is a theoretical model of the ill person, based mainly on literary texts, but with reference to a variety of scientific and popular-scientific material. The point of departure is the classic postcolonial theorist, Frantz Fanon, in whose writings medicine, healing, and discourse on such topics are seen as the functioning of a specific colonial practice. The most notable characteristic of the figure of the Estonian patient is non-communicativeness. Communication is avoided and feared primarily because it has to be directed toward those in higher positions of power, or to institutions that embody power (the apothecary, the hospital. While these traits also characterize the separation between peasants and their rulers more generally, in a situation of illness the exclusion is felt with a double intensity. Sickness casts the peasant in a double bind: when in need of help or healing, contact across the divide between social rank, and – more broadly, between two cultures and ways of understanding the world, becomes unavoidable. In such situations, illness signifies an intensification of the gap in social standing. The ill person, who already stands on a lower rung of the social hierarchy, becomes all the more marginalized. In keeping with these observations, the real reason behind indecisiveness and refusal of medical treatment may well be an effort to avoid or postpone humiliation on the basis of lower social standing. Other contributing factors might include unconscious resistance – or even a conscious model of resistance – in the psyche, which manifests as an avoidance of communication. The content and motivating force for the model is not heroism, but rather a sense of shame. Indeed, behind the context of medical culture lurks ethnic and material isolation. The individual’s economic situation, living conditions, education and – most important – his

  6. Critical Success Factors and information needs in Estonian industry

    Directory of Open Access Journals (Sweden)

    Aiki Tibar

    2002-01-01

    Full Text Available The article reports the results of the study on the critical success factors and related information needs in Estonian industry conducted in 1999. Data were collected by interviews with 27 managers and engineers from 16 manufacturing companies in various industries. Most of the critical success factors taken up were related to marketing, information management, quality management, product development and technological innovations. The information needs of managers and engineers were related to competitors, customers, markets, technology, regulations, etc. Some identified CSFs expressed also priorities for development by Estonian economic authorities: to support the implementation of new technologies and introduction of quality management methods. The finding that information management was perceived as a very critical area supports the result of the recent Finnish study on CSFs.

  7. Rupturing otherness: becoming Estonian in the context of contemporary Britain.

    Science.gov (United States)

    Märtsin, Mariann

    2010-03-01

    While identity construction continues to be a widely discussed and researched area in contemporary social sciences, the existing theories have overlooked the importance of understanding why and how identities as semiotic constructions emerge in individuals' consciousness in the flow of their everyday functioning. This article seeks to address this limitation in the theorizing by proposing an alternative conceptualization of identity, according to which identity construction is triggered by rupturing life-experience, which surfaces another perspective and makes the person aware of a possibility to be otherwise or of the reality of being different. Theoretical claims put forward in the paper are drawn from data gathered in a recent study, which explored lived-through experiences of young Estonians, who made study-visits to the United Kingdom. The discussed data will also highlight some interesting aspects in Estonians' self-definition as it is constructed in relation to Eastern-European identity in the context of contemporary Britain.

  8. Exhibition of photography from the Estonian diaspora / Ellu Maar

    Index Scriptorium Estoniae

    Maar, Ellu, 1982-

    2010-01-01

    Näitus "Photography from the Estonian Diaspora / Väliseesti foto" Kumu Kunstimuuseumis 8.10.-19.11.2010, kuraatorid Eha Komissarov ja Ellu Maar. Näitus tutvustas 1944. a. Eestist lahkunud või juba võõrsil sündinud fotograafide (Eric Soovere, Karl Hintzer, Priit Vesilind, Rein Välme jt.) loomingut ja valikut väliseesti fotoarhiividest

  9. Estonian Leader's Freedom Call Creates Storm / Anna Smolchenko

    Index Scriptorium Estoniae

    Smolchenko, Anna

    2008-01-01

    President Toomas Hendrik Ilvese esinemisest soome-ugri rahvaste maailmakongressil Hantõ-Mansiiskis, kohtumisest Venemaa presidendi Dmitri Medvedeviga, Eesti delegatsiooni saalist väljamarssimisest Venemaa riigiduuma väliskomisjoni esimehe Konstantin Kossatshovi sõnavõtu ajal. Ilmunud ka: St. Petersburg Times 1. juuli 2008, pealk.: Estonian Leader's Freedom Call Creates Controversy (lüh.). Vabariigi President töövisiidil Venemaal 27.-30.06.2008

  10. Efficiency of Estonian grain farms in 2000 2004

    Directory of Open Access Journals (Sweden)

    N. VASILIEV

    2008-12-01

    Full Text Available The aim of this study is to analyse the efficiency of Estonian grain farms after Estonia’s transition to a market economy and during the accession period to the European Union (EU. The non-parametric method Data Envelopment Analysis (DEA was used to estimate the total technical, pure technical and scale efficiency of Estonian grain farms in 2000–2004. Mean total technical efficiency varied from 0.70 to 0.78. Of the grain farms 62% are operating under increasing returns to scale. Solely based on the DEA model it is not possible to determine optimum farm scale and the range of Estonian farm sizes operating efficiently is extensive. The most pure technically efficient farms were the smallest and the largest but the productivity of small farms is low compared to larger farms because of their small scale. Therefore, they are the least competitive. Since pre-accession period to the EU, large input slacks of capital have replaced the former excessive use of labour and land. This raises the question about the effects on efficiency of the EU’s investment support schemes in new member states.;

  11. Revisiting the Estonian Cyber Attacks: Digital Threats and Multinational Responses

    Directory of Open Access Journals (Sweden)

    Stephen Herzog

    2011-01-01

    Full Text Available In April 2007, the Estonian Government moved a memorial commemorating the Soviet liberation of the country from the Nazis to a less prominent and visible location in Tallinn. This decision triggered rioting among Russian-speaking minorities and cyber terrorism targeting Estonia's critical economic and political infrastructure. Drawing upon the Estonian cyber attacks, this article argues that globalization and the Internet have enabled transnational groups—such as the Russian diaspora—to avenge their grievances by threatening the sovereignty of nation-states in cyberspace. Sophisticated and virtually untraceable political "hacktivists" may now possess the ability to disrupt or destroy government operations, banking transactions, city power grids, and even military weapon systems. Fortunately, western countries banded together to effectively combat the Estonian cyber attacks and minimize their effects. However, this article concludes that in the age of globalization, interdependence, and digital interconnectedness, nation-states must engage in increased cooperative cyber-defense activities to counter and prevent devastating Internet attacks and their implications.

  12. Factorial structure of SILL revisited: adaptation of SILL for Estonian EFL learners

    Directory of Open Access Journals (Sweden)

    Katrin Saks

    2015-04-01

    Full Text Available The present study aims to contribute to the understanding of the taxonomy of language learning strategies (Oxford 1990: 14–22 and its measuring instrument, the Strategy Inventory for Language Learning (SILL, through the adaptation process of the Estonian version. The translated version of the SILL was pilot-tested with a sample of 337 tertiary students. Cronbach’s alpha (0.91 reveals an acceptable reliability of the instrument. The t-test that was conducted in addition to descriptive analysis, to check for gender differences, did not reveal any significant differences. The results of the exploratory factor analysis did not support the 2- or 6-factor structures but the 9-factor analysis provides a good comparison to similar studies published in 1995 (Oxford, Burry-Stock 1995. The ethnic and gender differences of the results are discussed from the cultural perspective.

  13. [Reference values for the 6-minutes walking test in healthy Chilean children].

    Science.gov (United States)

    Gatica, Darwin; Puppo, Homero; Villarroel, Gregory; San Martín, Iván; Lagos, Rossana; Montecino, Juan José; Lara, Cristian; Zenteno, Daniel

    2012-08-01

    The 6-minutes walking test (6WT) is the ideal submaximal test for the evaluation and follow-up of patients with chronic respiratory diseases. There are no reference values (RV) for Chilean children using the American Thoracic Society guidelines. To generate 6WT reference values for Chilean children aged 6 to 14 years. 6MW was evaluated in 192 healthy children (100 women) aged between 6 and 14 years. The test was carried out in a 30 m long indoor flat surface. Children also answered a survey about health problems and their weight and height were recorded. The distance walked by women and men was 596.5 ± 57 and 625 ± 59.7 m respectively (p < 0.05). There was a significant correlation between the distance walked and height (r = 0.58), age (r = 0.56), weight (r = 0.54) and reserve heart rate (r = 0.21). These results can be used as reference values for the 6WT in Chilean children aged 6 to 14 years. They are similar to those reported abroad.

  14. Olev Schults : SAS vajab Estonian Airi rahvusliku lennufirmana / Olev Schults ; interv. Andres Reimer

    Index Scriptorium Estoniae

    Schults, Olev

    2008-01-01

    Estonian Airi nõukogu esimees vastab küsimustele, kas SAS arendas Läti airBalticut Estonian SAS-i arvel, mis mõte on rahvuslikul lennukompaniil, kui riik ei tohi seda finantseerida, kuidas mõjutab investorite meeleolu SAS-i Eestis tabanud poliitikute kriitika tulv

  15. Estonian Air jäi kolmest Fokkerist ilma / Toivo Tänavsuu

    Index Scriptorium Estoniae

    Tänavsuu, Toivo

    2006-01-01

    Estonian Airil ei õnnestunud saada kolme väiksemat reaktiivlennukit, lennuparki püütakse mitmekesistada järgmistel aastatel. Sel aastal loodetakse saada juurde ühe Boeing 737-300. Lisa: Boeing: Estonian Air on tasemel

  16. The Representation of the Cold War in Three Estonian History Textbooks

    Science.gov (United States)

    Korbits, Keit

    2015-01-01

    The article looks at the discursive strategies different Estonian history textbooks employ to represent the Cold War period, and the "commonsense" ideologies instilled through these representations. The textbooks analysed include two history books dating back to the Estonian Soviet Socialist Republic and, for contrast, one written during…

  17. Results of Genetic Testing in 855 Consecutive Unrelated Patients Referred for Long QT Syndrome in a Clinical Laboratory

    NARCIS (Netherlands)

    Lieve, Krystien V.; Williams, Leah; Daly, Amy; Richard, Gabriele; Bale, Sherri; Macaya, Daniela; Chung, Wendy K.

    2013-01-01

    Aim: Our aim was to examine the diagnostic yield of genetic testing in 855 consecutive unrelated cases referred for Long QT syndrome (LQTS). Results: Eight hundred fifty five consecutive patients with a mean age at testing of 27.5±18.6 years, were referred for LQTS genetic testing and had

  18. Tests of Coordinate Transfer from Magnetic to Mechanical Reference for LCLS Undulator Fiducialization

    Energy Technology Data Exchange (ETDEWEB)

    Levashov, Yu.

    2010-12-13

    Fiducialization of the LCLS undulators will be based on magnetic measurements by Hall probe. Pointed magnets, proposed by I.Vasserman for quadrupole lens fiducialization will be used as an intermediate reference. A prototype of the pointed magnet fixture has been made and tested. In this note we will describe a procedure for measuring the position of the center of the Hall probe sensitive area with respect to the undulator fiducial marks. The pointed magnet calibration procedure, a two-point algorithm for locating the magnetic center of the fixture, and test results are presented.

  19. Analysis Of Covariance Structure Tests Of A Criterial Referents Theory Of Attitudes.

    Science.gov (United States)

    Kerlinger, F N

    1980-10-01

    To test a criterial referents theory of social attitudes, data obtained in the 1960's and 1970's from factor analyses of social attitudes scales administered to students in the U. S. and Europe and to a random sample of Dutch citizens were reanalyzed using an analysis of covariance structure approach. The two-factor model of the basic hypothesis of the theory -- two relatively orthogonal second-order factors, liberalism (L) and conservatism (C), underlie social attitudes -- was tested against the one-factor model of the assumption of attitude bipolarity -- attitudes have positive and negative poles (L versus C). Although the results of the separate tests of the fit of the two models were mixed, contrast tests of the two models favored the two-factor (dualistic) hypothesis.

  20. Working memory and reference memory tests of spatial navigation in mice (Mus musculus).

    Science.gov (United States)

    Lee, Sang Ah; Tucci, Valter; Sovrano, Valeria Anna; Vallortigara, Giorgio

    2015-05-01

    Researchers in spatial cognition have debated for decades the specificity of the mechanisms through which spatial information is processed and stored. Interestingly, although rodents are the preferred animal model for studying spatial navigation, the behavioral methods traditionally used to assess spatial memory do not effectively test the predictions of specificity in their representation. To address such issues, the present study tested the ability of mice to use boundary geometry and features to remember a goal location across 2 types of tasks--a working memory task with a changing goal location, and a reference memory task with 1 rewarded goal location. We show for the first time that mice, like other animals, can successfully encode boundary geometry in a working memory spatial mapping task, just as they do in a reference memory task. Their use of a nongeometric featural cue (striped pattern), in contrast, was more limited in the working memory task, although it quickly improved in the reference memory task. We discuss the implications of these findings for future research on the neural and genetic underpinnings of spatial representations. (c) 2015 APA, all rights reserved).

  1. Trends in referral patterns, invasive management, and mortality in elderly patients referred for exercise stress testing.

    Science.gov (United States)

    Bouzas-Mosquera, Alberto; Peteiro, Jesús; Broullón, Francisco J; Calviño-Santos, Ramón; Mosquera, Víctor X; Barbeito-Caamaño, Cayetana; Larrañaga-Moreira, José María; Maneiro-Melón, Nicolás; Álvarez-García, Nemesio; Vázquez-Rodríguez, José Manuel

    2015-12-01

    Scarce data are available on the temporal patterns in clinical characteristics and outcomes of elderly patients referred for exercise stress testing. We aimed to assess the trends in baseline characteristics, tests results, referrals for invasive management, and mortality in these patients. We evaluated 11,192 patients aged ≥65years who were referred for exercise stress testing between January 1998 and December 2013. Calendar years were grouped into four quadrennia (1998-2001, 2002-2005, 2006-2009, and 2010-2013), and trends in clinical characteristics of the patients, type and results of the tests, referrals for invasive management, and mortality across the different periods were assessed. Despite a progressive decrease in the proportion of patients with non-interpretable baseline electrocardiograms or prior history of coronary artery disease, there was a gradual and marked increase in the use of cardiac imaging from 32.8% in 1998-2001 to 67.6% in 2010-2013 (ptesting both without imaging (from 18.9 to 13.6%, pmortality also decreased progressively from 3% to 1.6% (ptesting, we observed a decline over time in the probability of inducible myocardial ischemia, an increase in the use of cardiac imaging and in the rate of coronary revascularization, and an improvement in the survival rate at 1year. Copyright © 2015 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  2. Comparative analysis of idiom selection and sequencing 5 in Estonian basic school EFL coursebooks

    Directory of Open Access Journals (Sweden)

    Rita Anita Forssten

    2017-05-01

    Full Text Available The article investigates the selection and sequencing of the idioms encountered in two locally-produced and international coursebook series currently employed in Estonian basic schools. It is hypothesized that there exists a positive correlation between idioms’ difficulty and coursebooks’ language proficiency level. The hypothesis is tested through a statistical analysis of the idioms found which are categorized in terms of their analysability into three categories where category 1 includes analysable semi-literal idioms, category 2 comprises analysable semi-transparent idioms, and category 3 encompasses non-analysable opaque idioms, and then analysed through an online language corpus (British National Corpus. The results of the study reveal that the coursebook authors under discussion have disregarded idioms’ frequency as a criterion for selection or sequencing, whereas the factor utilized to some extent is the degree of analysability.

  3. Preparation of reference strains for validation and comparison of mycoplasma testing methods.

    Science.gov (United States)

    Dabrazhynetskaya, A; Volokhov, D V; David, S W; Ikonomi, P; Brewer, A; Chang, A; Chizhikov, V

    2011-10-01

    To optimize growth conditions for preparation of stocks of mycoplasma reference strains to obtain highly viable and disperse samples with low ratios of genomic copy (GC) number to that of colony forming units (CFU). These stocks are required for assessment of relative limits of detection (LOD) of alternative nucleic acid testing (NAT)-based methods in comparison to the conventional microbiological methods. A kinetics study was used to assess the changes in ratios between the numbers of GC and CFU at different growth phases of six different mycoplasma cultures Acholeplasma laidlawii, Mycoplasma gallisepticum, Mycoplasma arginini, Mycoplasma fermentans, Mycoplasma orale and Mycoplasma pneumoniae. All tested mycoplasmas demonstrated low GC/CFU ratios (≤ 10) within the log and early stationary growth phases. A significant increase in GC/CFU ratios was observed at the very late stationary and death phases, when the titre of cultures has declined. Similar patterns of GC/CFU profiles were observed for A. laidlawii and Myc. gallisepticum co-cultured with suspension of Chinese hamster ovary (CHO) cells. Tested mycoplasma strains harvested at the exponential-early stationary phases of growth demonstrated the lowest GC/CFU ratios and low propensity to form filamentous structures or aggregates under proposed conditions and can be used for the preparation of a mycoplasma reference panel for methods comparability study. This study shows that the preparation and use of viable mycoplasma reference strains with low CG/CFU ratios is the most reliable way to adequately evaluate the LOD of alternative NAT-based mycoplasma testing methods. Journal of Applied Microbiology © 2011 The Society for Applied Microbiology. No claim to US Government works.

  4. Trends in smoking behaviour among Estonian physicians in 1982–2014

    Directory of Open Access Journals (Sweden)

    Kersti Pärna

    2017-07-01

    Full Text Available Abstract Background Smoking surveys among physicians have proved useful in highlighting the importance of physicians as healthy life style exemplars and role models in tobacco control and smoking cessation. The aim of this study was to give an overview of smoking behaviour among Estonian physicians from 1982 to 2014. Methods Three cross-sectional postal surveys using a self-administered questionnaire were carried out among all practising physicians in Estonia. The number of physicians participating in this study was 3786 in 1982, 2735 in 2002, and 2902 in 2014. Data analysis involved calculating the age-standardized prevalences of smoking, prevalences of smoking by age group and mean age of smoking initiation. A non-parametric test for trend was used to assess significant changes in smoking over time. Results Age-standardized prevalence of current smoking among men was 39.7% in 1982, 20.9% in 2002, and 14.3% in 2014 and among women 12.2%, 8.0%, and 5.2%, respectively (p < 0.0001 for trends. From 1982 to 2014, the biggest decline of current smoking among men and women was in age groups under 35 (from 55.2% to 16.7% and from 16.7% to 2.8%, respectively and 35–44 (from 47.1% to 8.3% and from 19.5% to 5.1%, respectively (p < 0.0001 for trends. Mean age of smoking initiation decreased from 20.4 to 19.3 among men and from 24.5 to 20.4 among women over the study period. Conclusions In 1982–2014, smoking prevalence among Estonian physicians declined substantially. This may influence the willingness of society to recognize the health consequences of smoking which could give a support to the decline of the smoking epidemic in the country. Differences between smoking among male and female physicians persisted over the study period, but mean age of smoking initiation decreased. A further decline in smoking among Estonian physicians should be encouraged by special efforts targeted at physicians.

  5. A permeation-controlled formaldehyde reference source for application in environmental test chambers.

    Science.gov (United States)

    Salthammer, Tunga; Giesen, Ruth; Schripp, Tobias

    2017-10-01

    In a wide range of indoor air pollutants, formaldehyde is one of the most-used and best-known substances. In order to protect human health, many countries have established threshold values for the release of formaldehyde from miscellaneous products and revise them constantly. Compliance with these regulations is usually assessed by emission test chamber measurements or derived methods. To control and improve the mechanisms of an emission test chamber, a reliable reference source with sample mimicking emission properties is required but not available so far. This study describes a permeation-controlled reference source based on the application of paraformaldehyde as formaldehyde releasing polymeric compound. Interactions between the formaldehyde release of the source and the governing chamber parameters temperature, relative humidity and air velocity were investigated in 1 m(3) emission chambers. Depending on the conditions, constant formaldehyde concentrations between approximately 10 ppb and 150 ppb can be adjusted for up to 600 h. A linear correlation between the logarithm of the chamber concentration and the reciprocal temperature was found. The results support the feasibility of the source for validation of emission test chamber performance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Developing a reference material for diffusion-controlled formaldehyde emissions testing.

    Science.gov (United States)

    Liu, Zhe; Liu, Xiaoyu; Zhao, Xiaomin; Cox, Steven S; Little, John C

    2013-11-19

    Formaldehyde, a known human carcinogen and mucous membrane irritant, is emitted from a variety of building materials and indoor furnishings. The drive to improve building energy efficiency by decreasing ventilation rates increases the need to better understand emissions from indoor products and to identify and develop lower emitting materials. To help meet this need, formaldehyde emissions from indoor materials are typically measured using environmental chambers. However, chamber testing results are frequently inconsistent and provide little insight into the mechanisms governing emissions. This research addresses these problems by (1) developing a reference formaldehyde emissions source that can be used to validate chamber testing methods for characterization of dynamic sources of formaldehyde emissions and (2) demonstrating that emissions from finite formaldehyde sources can be predicted using a fundamental mass-transfer model. Formaldehyde mass-transfer mechanisms are elucidated, providing practical approaches for developing diffusion-controlled reference materials that mimic actual sources. The fundamental understanding of emissions mechanisms can be used to improve emissions testing and guide future risk reduction actions.

  7. Usability Testing Analysis on The Bana Game as Education Game Design References on Junior High School

    Directory of Open Access Journals (Sweden)

    F. Adnan

    2017-04-01

    Full Text Available Learning media is one of the important elements in the learning process. Technological development support makes learning media more varied. The approach of using digital technology as a learning media has a better and more effective impact than other approaches. In order to increase the students’ learning interest, it requires the support of an interesting learning media. The use of gaming applications as learning media can improve learning outcomes. The benefits of using the maximum application cannot be separated from the determination of application design. The Bana game aims to increase the ability of critical thinking of the junior high school students. The usability-testing analysis on the Bana game application is used in order to get the design reference as an educational game development. The game is used as an object of the analysis because it has the same characteristics and goals with the game application to be developed. Usability Testing is a method used to measure the ease of use of an application by users. The Usability Testing consists of learnability, efficiency, memorability, errors, and satisfaction. The results of the analysis obtained will be used as a reference for educational game applications that will be developed.

  8. Early HIV infection among persons referred for malaria parasite testing in Nigeria.

    Science.gov (United States)

    Olusola, Babatunde A; Olaleye, David O; Odaibo, Georgina N

    2018-02-01

    Persons in the early stages of HIV infection are the major drivers of new infections. These individuals may also develop renal dysfunctions at this time. Nigeria, as other African countries, has one of the highest prevalence of newly diagnosed HIV infections. Despite this, limited information exists on early HIV detection in the continent. This may be related to difficulties in providing early HIV diagnosis and treatment. Patients referred for malaria testing may provide a unique opportunity for early HIV detection. In this study, a method for identifying early HIV-infected individuals was assessed. HIV-1 subtype and renal function biomarkers were also analyzed in these persons. To identify early HIV infection, over a period of 18 months blood samples were collected from persons referred by clinicians for malaria parasite tests in Nigeria. A total of 671 samples were collected and analyzed for HIV antigen/antibody and subtypes. 101 of these samples were categorized into one of four groups: early HIV, chronic HIV, malaria infection and control groups for renal function analysis. 29% of HIV infected individuals were at the early stages of infection. The predominant subtype detected was CRF02_AG (57.14%). The early HIV group had the highest mean serum creatinine (95 µmol/L) and urea (5.7 mmol/L) values across all groups with the difference significant at P HIV infection. Our results show the feasibility of screening persons referred for malaria tests for early HIV. This can be used to control new HIV infections in sub-Saharan Africa.

  9. Väliseestlased ja nende keel. Pidepunkte uurimisloost / A study of the Estonian language in diaspora

    Directory of Open Access Journals (Sweden)

    Jüri Viikberg

    2012-01-01

    Full Text Available The varieties of the Estonian language outside Estonia, differing from standard Estonian spoken in Estonia, are regional and generally oral language variants, influenced by local factors and variable intergenerational use. Containing loans from the dominant language, the oral language of the older generation still retains features either redundant or marginal in the current Estonian language geographic area. The first written documents on expatriate Estonians date back to the 19th century, but it was only after the Republic of Estonia was established in 1918 that a wider interest was taken in compatriots living abroad. In 1928, the Expatriate Estonian Society (Välis-Eesti Ühing was founded and the Expatriate Estonian Congress (Välis-Eesti kongress started to be held every five years. After Estonia was annexed by the Soviet Union in 1940, the word väliseestlane ’expatriate Estonian’ was used only in connection with Estonians living outside the Soviet Union. In the 1950s and 1960s, linguists became specifically interested in the Estonian settlements of Caucasus, Siberia and Ussuriland. Scholars, hoping to find in Siberia or Caucasus the archaic language of former settlers still alive, discovered that vernacular Estonian was not influenced so much by archaisms (caused by separation from the homeland as influences from long-term contact with other languages.Since the late 1990s, the study of the varieties of Estonian used outside Estonia has taken a new direction. This can be recognised by the increased interest in the varieties of Estonian in various new countries of residence (e.g. Denmark, Finland, Germany. The focus of interest moving to western countries did not mean a loss of interest in the areas of the former Soviet empire. In 1996, the Centre for Migration and Diaspora Studies was set up in the Tartu University Institute of Geography. Presently, one of the prestigious research projects (2010−2013 of Finno-Ugric languages, the EU

  10. Direct force measurements for testing the LISA Pathfinder gravitational reference sensor

    Energy Technology Data Exchange (ETDEWEB)

    Cavalleri, A [Centro Fisica degli Stati Aggregati, 38050 Povo (Italy); Ciani, G; Dolesi, R; Hueller, M; Nicolodi, D; Tombolato, D; Wass, P J; Weber, W J; Vitale, S; Carbone, L, E-mail: wass@science.unitn.i [Dipartimento di Fisica, Universita di Trento, and INFN Gruppo collegato di Trento, via Sommarive 14, 38050 Povo (Italy)

    2009-05-07

    We present results of testing of the LISA Pathfinder gravitational reference sensor (GRS) using a 4-test-mass torsion pendulum facility aimed at measuring low-frequency force-noise sources in the LISA and LISA Pathfinder frequency band. This pendulum, for the first time, allows us to make measurements which are sensitive to all forces acting along the sensitive axis of the test mass, not only those that create a torque. We will report on a campaign of testing using the LISA Pathfinder 'engineering model' prototype GRS which has set upper limits on the overall force noise acting on the test mass contributed by surface effects within the sensor at a level of 100 fN Hz{sup -1/2} at 2 mHz and measured specific sources of unwanted disturbances. These sources include forces arising from the electrostatic coupling between the sensor and test-mass motion, electrostatic fields due to surface-potential variations and thermal-gradient effects within the sensor. Finally, we describe the extension of this campaign to the LISA Pathfinder flight-model replica GRS which will be crucial in verifying the design and performance of the flight instrument.

  11. Life satisfaction and its correlates among college students in China: a test of social reference theory.

    Science.gov (United States)

    Zhang, Jie; Zhao, Sibo; Lester, David; Zhou, Chengchao

    2014-08-01

    To study life satisfaction and to test the role of social reference in determining the degree of life satisfaction, we examined a large sample of undergraduate students in China for the correlates of campus life satisfaction. A questionnaire survey was administered at a university and the final sample consisted of 439 respondents aged between 17 and 24 years, from all over the country, and studying different subjects. It was found that freshman students tended to score higher on their life satisfaction than students in other grades and the college students' life satisfaction was positively related to female gender, self-esteem, social support, and the liberal attitudes on female gender roles, but negatively correlated with depression and suicidal ideation. Contrary to common beliefs, students from an urban area or from better-off families were not necessarily more satisfied with current life than those students coming from the countryside or low income families. The findings were accounted for by the social reference theory and in this case college students' campus life satisfaction is basically affected by their pre-college life quality as a reference. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. HIV incidence in the Estonian population in 2013 determined using the HIV-1 limiting antigen avidity assay.

    Science.gov (United States)

    Soodla, P; Simmons, R; Huik, K; Pauskar, M; Jõgeda, E-L; Rajasaar, H; Kallaste, E; Maimets, M; Avi, R; Murphy, G; Porter, K; Lutsar, I

    2017-08-01

    Estonia has one the highest number of new HIV diagnoses in the European Union, mainly among injecting drug users and heterosexuals. Little is known of HIV incidence, which is crucial for limiting the epidemic. Using a recent HIV infection testing algorithm (RITA) assay, we aimed to estimate HIV incidence in 2013. All individuals aged ≥18 years newly-diagnosed with HIV in Estonia January- December 2013, except blood donors and those undergoing antenatal screening, were included. Demographic and clinical data were obtained from the Estonian Health Board and the Estonian HIV-positive patient database. Serum samples were tested for recent infection using the LAg-avidity EIA assay. HIV incidence was estimated based on previously published methods. Of 69,115 tested subjects, 286 (0.41%) were newly-diagnosed with HIV with median age of 33 years (IQR: 28-42) and 65% male. Self-reported routes of HIV transmission were mostly heterosexual contact (n = 157, 53%) and injecting drug use (n = 62, 21%); 64 (22%) were with unknown risk group. Eighty two (36%) were assigned recent, resulting in estimated HIV incidence of 0.06%, corresponding to 642 new infections in 2013 among the non-screened population. Incidence was highest (1.48%) among people who inject drugs. These high HIV incidence estimates in Estonia call for urgent action of renewed targeted public health promotion and HIV testing campaigns. © 2017 British HIV Association.

  13. Mechanical design of the University of Florida Torsion Pendulum for testing the LISA Gravitational Reference Sensor

    Science.gov (United States)

    Shelley, Ryan; Chilton, Andrew; Olatunde, Tawio; Ciani, Giacomo; Mueller, Guido; Conklin, John

    2014-03-01

    The Laser Interferometer Space Antenna (LISA) requires free falling test masses, whose acceleration must be below 3 fm/s2/rtHz in the lower part of LISA's frequency band ranging from 0.1 to 100 mHz. Gravitational reference sensors (GRS) house the test masses, shield them from external disturbances, control their orientation, and sense their position at the nm/rtHz level. The GRS torsion pendulum is a laboratory test bed for GRS technology. By decoupling the system of test masses from the gravity of the Earth, it is possible to identify and quantify many sources of noise in the sensor. The mechanical design of the pendulum is critical to the study of the noise sources and the development of new technologies that can improve performance and reduce cost. The suspended test mass is a hollow, gold-coated, aluminum cube which rests inside a gold-coated, aluminum housing with electrodes for sensing and actuating all six degrees of freedom. This poster describes the design, analysis, and assembly of the mechanical subsystems of the UF Torsion Pendulum.

  14. Modifications of the MUlti stimulus test with Hidden Reference and Anchor (MUSHRA) for use in audiology.

    Science.gov (United States)

    Völker, Christoph; Bisitz, Thomas; Huber, Rainer; Kollmeier, Birger; Ernst, Stephan M A

    2016-09-06

    Two modifications of the standardised MUlti Stimulus test with Hidden Reference and Anchor (MUSHRA), namely MUSHRA simple and MUSHRA drag&drop, were implemented and evaluated together with the original test method. The modifications were designed to maximise the accessibility of MUSHRA for elderly and technically non-experienced listeners, who constitute the typical target group in hearing aid evaluation. Three MUSHRA variants were assessed based on subjective and objective measures, e.g. test-retest reliability, discrimination ability, time exposure and overall preference. With each method, participants repeated the task to rate the quality of several hearing aid algorithms four times. Fifty listeners grouped into five subject classes were tested, including elderly and technically non-experienced participants with normal and impaired hearing. Normal-hearing, technically experienced students served as controls. Both modifications can be used to obtain compatible rating results. Both were preferred over the classical MUSHRA procedure. Technically experienced listeners performed best with the modification MUSHRA drag&drop. The comprehensive comparison of the MUSHRA variants demonstrates that the intuitive modification MUSHRA drag&drop can be generally recommended. However, considering e.g. specific evaluation demands, we suggest a differentiated and careful application of listening test methods.

  15. Estonian Language of Technology as a Factor Supporting the Evolution of Engineering Thinking

    Directory of Open Access Journals (Sweden)

    Mägi, Vahur

    2013-03-01

    Full Text Available Casual mention of teaching technology subjects in Estonian schools dates back several centuries. Navigation and construction were amongthe earliest professional skills that were taught. As both of them required mathematical thinking skills, teaching the subjects was usually accompanied by explaining the principles of mathematics. The first technology book in Estonian was published about two centuries ago and it dealed with geodesy. The earliest Estonian glossaries of technological terminology were published in the fields of physics and chemistry. The rise of Estonian as a language of higher education and science in the country came about in the 1920s and 1930s. Faculty members of the Tallinn School of Technology then published the first textbooks composed in the Estonian language for students of technology. The Estonian Society for Technology and the Estonian Association of Engineers became seriously involved in linguistic activities. Together with the Vocational Teachers’ Assembly of Tartu they published an illustrated technology glossary for machinery and tools terms. It was followed by a glossary of construction and building terms, compiled under the lead of the University of Technology. In addition, journals of technology introducedinnovations in the lexicon of technology to the general public. The postwar period in the development of the lexicon of technical terms was of little significance at first. A surge in language creativity could be detected in the 1960s, when terminology became a target of constantly growing attention to the development of technology lexicon. Series of technology glossaries were published. This tendency has continued to this day.

  16. Mechanography in childhood: references for force and power in counter movement jumps and chair rising tests.

    Science.gov (United States)

    Busche, P; Rawer, R; Rakhimi, N; Lang, I; Martin, D D

    2013-06-01

    We sought to procure age- and gender- related reference data and study the characteristics of body weight related peak force (pFrel), body mass related peak power (pPrel) for counter movement jumps (single two-legged jumps, s2LJ) and chair rising tests (CRT) in children. We examined 868 healthy participants (436 female) aged 3 to 19 years. Weight-related results of the s2LJ and CRT Mechanography parameters were reported. pPrel during s2LJ (pPrel(s2LJ)) increased linearly with age for males age 5 to 19 and female age 5 to 11 at a rate of 4.6 W/kg per year. pPrel(s2LJ) for females age 12 to 19 increased only by 2.5 W/kg. CRT time per repetition was 1.065 s, independent of age and gender. pPrel per body mass during the rise phase (pPrel(CRT)) showed similar but smaller age and gender relations as peak power during s2LJ. pFrel was 2.5 g (multiples of earth's gravity) for s2LJ and 1.5 g for CRT. This data from normal children from a healthy Caucasian population provide reference values for tests that reflect everyday motor function.

  17. Effects of ventilation behaviour on indoor heat load based on test reference years

    Science.gov (United States)

    Rosenfelder, Madeleine; Koppe, Christina; Pfafferott, Jens; Matzarakis, Andreas

    2016-02-01

    Since 2003, most European countries established heat health warning systems to alert the population to heat load. Heat health warning systems are based on predicted meteorological conditions outdoors. But the majority of the European population spends a substantial amount of time indoors, and indoor thermal conditions can differ substantially from outdoor conditions. The German Meteorological Service (Deutscher Wetterdienst, DWD) extended the existing heat health warning system (HHWS) with a thermal building simulation model to consider heat load indoors. In this study, the thermal building simulation model is used to simulate a standardized building representing a modern nursing home, because elderly and sick people are most sensitive to heat stress. Different types of natural ventilation were simulated. Based on current and future test reference years, changes in the future heat load indoors were analyzed. Results show differences between the various ventilation options and the possibility to minimize the thermal heat stress during summer by using an appropriate ventilation method. Nighttime ventilation for indoor thermal comfort is most important. A fully opened window at nighttime and the 2-h ventilation in the morning and evening are more sufficient to avoid heat stress than a tilted window at nighttime and the 1-h ventilation in the morning and the evening. Especially the ventilation in the morning seems to be effective to keep the heat load indoors low. Comparing the results for the current and the future test reference years, an increase of heat stress on all ventilation types can be recognized.

  18. The reciprocal internal/external frame of reference model using grades and test scores.

    Science.gov (United States)

    Möller, Jens; Zimmermann, Friederike; Köller, Olaf

    2014-12-01

    The reciprocal I/E model (RI/EM) combines the internal/external frame of reference model (I/EM) with the reciprocal effects model (REM). The RI/EM extends the I/EM longitudinally and the REM across domains. The model predicts that, within domains, mathematics and verbal achievement (VACH) and academic self-concept have positive effects on subsequent mathematics and VACH and academic self-concept within domains but have negative effects across domains. The main purpose is to validate the RI/EM and extend it using objective achievement indicators and grades. Two waves of data collection from grade 5 to grade 9 with N = 1,045 secondary school students were used. Test scores, grades, and self-concept data were obtained. The main analyses were conducted using hierarchical linear modelling. The positive longitudinal effects of grades and test scores on subsequent grades, test scores and academic self-concept within domains and the negative effects of grades and test scores on subsequent academic self-concept across domains supported the RI/EM. The effects of academic self-concept on subsequent grades and test scores across domains were near zero when prior achievement indicators were controlled for. Overall, the results using school grades as achievement measures were replicated using standardized achievement test scores. The results serve to highlight the importance of the combination of common theories, which are mostly investigated individually, to enhance our understanding of the complexity of within- and across-domain relations between academic self-concepts and achievement using grades as well as test scores. © 2014 The British Psychological Society.

  19. Evaluation of ability of reference toxicity tests to identify stress in laboratory populations of the amphipod Hyalella azteca

    Science.gov (United States)

    McNulty, E.W.; Dwyer, F.J.; Ellersieck, Mark R.; Greer, E.I.; Ingersoll, C.G.; Rabeni, C.F.

    1999-01-01

    Standard methods for conducting toxicity tests imply that the condition of test organisms can be established using reference toxicity tests. However, only a limited number of studies have evaluated whether reference toxicity tests can actually be used to determine if organisms are in good condition at the start of a test. We evaluated the ability of reference toxicants to identify stress associated with starvation in laboratory populations of the amphipod Hyalella azteca using acute toxicity tests and four reference toxicants: KCl, CdCl2, sodium pentachlorophenate (NaPCP), and carbaryl. Stress associated with severe starvation was observed with exposure of amphipods to carbaryl or NaPCP but not with exposure to KCl or CdCl2 (i.e., lower LC50 with severe starvation). Although the LC50s for NaPCP and carbaryl were statistically different between starved and fed amphipods, this difference may not be biologically significant given the variability expected in acute lethality tests. Stress associated with sieving, heat shock, or cold shock of amphipods before the start of a test was not evident with exposure to carbaryl or KCl as reference toxicants. The chemicals evaluated in this study provided minimal information about the condition of the organisms used to start a toxicity test. Laboratories should periodically perform reference toxicity tests to assess the sensitivity of life stages or strains of test organisms. However, use of other test acceptability criteria required in standard methods such as minimum survival, growth, or reproduction of organisms in the control treatment at the end of a test, provides more useful information about the condition of organisms used to start a test compared to data generated from reference toxicity tests.

  20. Joint helmet-mounted cueing system accuracy testing using celestial references

    Science.gov (United States)

    Marticello, Daniel N., Jr.; Spillman, Mark S.

    1999-07-01

    The Joint Helmet-Mounted Cueing System (JHMCS) incorporates a man-mounted, ejection-compatible helmet-mounted display system, with the capability to cue and verify cueing of high off-axis sensors and weapons, on U.S. Air Force and U.S. Navy single-seat and two-seat fighter aircraft. Program requirements call for the JHMCS to meet a certain level of pointing accuracy. Pointing accuracy is defined as how close the JHMCS computed line of sight (LOS) is to the actual LOS of the pilot. In order to test the pointing accuracy of JHMCS throughout the pilot's range of motion, truth data had to be established sat various azimuths and elevations. Surveyed ground locations do not provide the ability to test at different helmet elevations. Airborne targets do not provide the measurement precision needed to validate system accuracy. Therefore, celestial bodies (stars), whose locations are precisely known for a given time and date at a specific location, will serve as truth data for LOS accuracy testing. This paper addresses the theory, planning, and status of JHMCS accuracy testing utilizing celestial bodies as reference points.

  1. Improved reclassification of mortality risk by assessment of physical activity in patients referred for exercise testing.

    Science.gov (United States)

    Myers, Jonathan; Nead, Kevin T; Chang, Peter; Abella, Joshua; Kokkinos, Peter; Leeper, Nicholas J

    2015-04-01

    Inability to meet minimal guidelines on physical activity is associated with poor health outcomes, but quantifying activity can be complex. We studied whether a simple question regarding participation in regular activity improves risk classification for all-cause mortality. Maximal exercise testing was performed in 6962 patients (mean age, 58.9 ± 11 years) for clinical reasons. Subjects also were assessed for participation in regular activity using a simple yes/no response to meeting minimal recommendations on activity. The incremental value of adding a simple physical activity assessment to clinical, demographic, and exercise test information to predict mortality was determined using Cox proportional hazards models, net reclassification improvement, and integrated discrimination index during a mean follow-up of 9.7 ± 4 years. Subjects who did not meet the minimal guidelines on activity had a lower exercise capacity (7.4 ± 4.3 vs 9.1 ± 3.6 metabolic equivalents, P mortality rate (2.42% vs 1.71%, P mortality (hazard ratio, 1.36; 95% confidence interval, 1.22-1.51, P test variables, fitness had the highest C-index for predicting mortality (0.72, P mortality among patients who are referred for exercise testing. Published by Elsevier Inc.

  2. Acceptance test of an activity meter to be used as reference in a calibration methodology establishment

    Energy Technology Data Exchange (ETDEWEB)

    Correa, Eduardo L.; Kuahara, Lilian T.; Potiens, Maria da Penha A., E-mail: educorrea1905@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2014-07-01

    The nuclear medicine is a medical physics area in which radiopharmaceuticals are used in diagnostic procedures. These radioactive elements are administered in the patient and the radiation emitted is detected by an equipment, that makes the body scan, connected to a computer software, and the image is constructed. In order to operate the nuclear medicine service must have calibrated radiation detectors. Thought, it does not exist, in Brazil, an activity meter calibration methodology, which causes many measurement uncertainties. The goal of this study is to present the acceptance test results of an activity meter to be used as reference in a new calibration methodology establishment. It was checked an activity meter Capintec, CRC-25R model, using three control sources ({sup 137}Cs, {sup 57}Co, {sup 133}Ba). The tests were based on the CNEN-NN 3.05 standard, the manufacturer manual, the TRS-454 and the TECDOC 602 and include: physical inspection, chamber voltage, zero adjustment, background response, data check and repeatability. The linearity and geometry tests could not be made, because the laboratory where the activity meter is located is not authorized to receive non-sealed radioactive sources. The equipment has presented a good behavior. All the results are in the range presented by national and international standards and the equipment is now being used in the laboratory and periodically passes through the quality control tests. (author)

  3. Subjective Well-Being Under Neuroleptics Scale short form (SWN-K): reliability and validity in an Estonian speaking sample.

    Science.gov (United States)

    Haring, Liina; Mõttus, René; Jaanson, Peeter; Pilli, Raine; Mägi, Kairi; Maron, Eduard

    2013-09-11

    The Subjective Well-Being Under Neuroleptic Treatment Scale short form (SWN-K) is a self-rating scale developed to measure mentally ill patients' well-being under the antipsychotic drug treatment. This paper reports on adaptation and psychometric properties of the instrument in an Estonian psychiatric sample. In a naturalistic study design, 124 inpatients or outpatients suffering from the first psychotic episode or chronic psychotic illness completed the translated SWN-K instrument. Item content analysis, internal consistency analysis, exploratory principal components analysis, and confirmatory factor analysis were used to construct the Estonian version of the SWN-K (SWN-K-E). Additionally, socio-demographic and clinical data, observer-rated psychopathology, medication side effects, daily antipsychotic drug dosages, and general functioning were assessed at two time points, at baseline and after a 29-week period; the associations of the SWN-K-E scores with these variables were explored. After having selected 20 items for the Estonian adaptation, the internal consistency of the total SWN-K-E was 0.93 and the subscale consistencies ranged from 0.70 to 0.80. Good test-retest reliabilities were observed for the adapted scale scores, with the correlation of the total score over about 6 months being r = 0.70. Confirmatory factor analysis replicated the presence of a higher-order factor (general well-being) and five first-order factors (mental functioning, physical functioning, social integration, emotional regulation, and self-control); the model fitted the data well. The results indicated a moderate-high correlations r = 0.54 between the SWN-K-E total score and the evaluation how satisfied patients were with their lives in generally. No significant correlations were found between the overall subjective well-being score and age, severity of the psychopathology, drug adverse effects, or prescribed drug dosage. Taken together, the results demonstrated that the Estonian

  4. Results of a Saxitoxin Proficiency Test Including Characterization of Reference Material and Stability Studies

    Directory of Open Access Journals (Sweden)

    Kirsi Harju

    2015-11-01

    Full Text Available A saxitoxin (STX proficiency test (PT was organized as part of the Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk (EQuATox project. The aim of this PT was to provide an evaluation of existing methods and the European laboratories’ capabilities for the analysis of STX and some of its analogues in real samples. Homogenized mussel material and algal cell materials containing paralytic shellfish poisoning (PSP toxins were produced as reference sample matrices. The reference material was characterized using various analytical methods. Acidified algal extract samples at two concentration levels were prepared from a bulk culture of PSP toxins producing dinoflagellate Alexandrium ostenfeldii. The homogeneity and stability of the prepared PT samples were studied and found to be fit-for-purpose. Thereafter, eight STX PT samples were sent to ten participating laboratories from eight countries. The PT offered the participating laboratories the possibility to assess their performance regarding the qualitative and quantitative detection of PSP toxins. Various techniques such as official Association of Official Analytical Chemists (AOAC methods, immunoassays, and liquid chromatography-mass spectrometry were used for sample analyses.

  5. Results of a Saxitoxin Proficiency Test Including Characterization of Reference Material and Stability Studies.

    Science.gov (United States)

    Harju, Kirsi; Rapinoja, Marja-Leena; Avondet, Marc-André; Arnold, Werner; Schär, Martin; Luginbühl, Werner; Kremp, Anke; Suikkanen, Sanna; Kankaanpää, Harri; Burrell, Stephen; Söderström, Martin; Vanninen, Paula

    2015-11-25

    A saxitoxin (STX) proficiency test (PT) was organized as part of the Establishment of Quality Assurance for the Detection of Biological Toxins of Potential Bioterrorism Risk (EQuATox) project. The aim of this PT was to provide an evaluation of existing methods and the European laboratories' capabilities for the analysis of STX and some of its analogues in real samples. Homogenized mussel material and algal cell materials containing paralytic shellfish poisoning (PSP) toxins were produced as reference sample matrices. The reference material was characterized using various analytical methods. Acidified algal extract samples at two concentration levels were prepared from a bulk culture of PSP toxins producing dinoflagellate Alexandrium ostenfeldii. The homogeneity and stability of the prepared PT samples were studied and found to be fit-for-purpose. Thereafter, eight STX PT samples were sent to ten participating laboratories from eight countries. The PT offered the participating laboratories the possibility to assess their performance regarding the qualitative and quantitative detection of PSP toxins. Various techniques such as official Association of Official Analytical Chemists (AOAC) methods, immunoassays, and liquid chromatography-mass spectrometry were used for sample analyses.

  6. Validation of a reference method for total cholesterol measurement in human serum and assignation of reference values to proficiency testing samples.

    Science.gov (United States)

    Heuillet, Maud; Lalere, Beatrice; Peignaux, Maryline; De Graeve, Jacques; Vaslin-Reimann, Sophie; Pais De Barros, Jean-Paul; Gambert, Philippe; Duvillard, Laurence; Delatour, Vincent

    2013-03-01

    Our objective was to develop a reference method to measure total cholesterol in human serum, in order to assign values and assess the accuracy of field methods in French clinical laboratories. A reference method based on gas chromatography coupled with mass spectrometry and isotope dilution (GC-IDMS) was developed and validated. It was then used to assign reference values to five frozen serum samples from voluntary proficiency testing schemes gathering 170 French clinical laboratories. Three peer groups were defined and bias against the reference method target value was calculated. Accuracy of the reference method was assessed against NIST SRM 1951b. Bias of the reference method was less than 0.5% and imprecision was less than 1.0%. Our study indicated that field methods tended to overestimate total cholesterol concentration, mean bias being +5.02% ± 1.02%. The most popular methods (phenolic chromogen with spectrophotometric detection, 80% of participants) exhibited the highest bias (peer group mean bias: +5.51 ± 1.24%). Neither these methods nor those using a non-phenolic chromogen with reflectometric detection (10% of participants, peer group mean bias: +4.20 ± 1.44%) met NCEP recommendations according to which bias should be less than 3%. Only the methods using a non phenolic chromogen with a spectrophotometric detection met these recommendations (10% of participants, peer group mean bias: +1.39 ± 2.75%). As all three peer groups provided positively biased results, the consensus mean usually used to assess the trueness of routine methods is biased as well, which results in an erroneous estimation of method bias. Therefore, this study highlights the value added by reference method target values to assess trueness of field methods and monitor performance of clinical laboratories. Copyright © 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  7. Exploring the sustainability of estonian forestry: the socioeconomic drivers.

    Science.gov (United States)

    Urbel-Piirsalu, Evelin; Bäcklund, Ann-Katrin

    2009-03-01

    Forestry as an important industry has both direct as well as indirect effects on the Estonian economy. It is therefore essential that it is sustainably managed so that it can continue to contribute to the economy in the future. The first aim of this article is to establish the situation regarding felling and regeneration in Estonia. As the available forestry statistics display discrepancies and lack consistency, it was as a necessary first step to gather information about and analyze the validity and reliability of the prime data to make the data sets useful for comparison over time and establish the current trends in Estonian forestry. However, with the help of interviews we are able to show that economic instability in Estonia brings with it increased logging rates and hinders investments into regeneration and maintenance. The problems are particularly pronounced in private forestry. Second, the article seeks to explain the socioeconomic reasons behind this situation. Economic problems among private owners, a liberal forestry policy, together with rapid land reform and weak enforcement of forestry legislation are some of the reasons that can explain the forestry trends in Estonia.

  8. Development of a breeding objective for Estonian Holstein cattle

    Directory of Open Access Journals (Sweden)

    E. PÄRNA

    2008-12-01

    Full Text Available Economic weights for milk carrier (water plus lactose, fat and protein yields, calving interval, age at first service, interval between the first service and conception of heifers and length of productive life of Estonian Holsteins were estimated under assumed milk production quota and for non-quota conditions. A bio-economic model of an integrated production system of a closed herd was used. Economic values of milk carrier yield and length of productive life differed between quota and non-quota conditions, but there were only minor differences between those marketing systems in economic values for functional traits. The standardised economic values of the most important traits varied in magnitude between18 to 81% of the economic value for milk yield. Discounting had a substantial impact on the economic value of length of productive life. When defining the breeding objective for Estonian Holstein, the interval between the first service and conception of heifers, and the length of productive life should be included in the breeding goal along with the traits with the highest economic value, milk, fat and protein yield. In the optimum breeding objective, relative weights of production vs. functional traits were 79 and 21%, respectively.;

  9. Lower Ordovician Leetse Formation in the North Estonian Klint area

    Directory of Open Access Journals (Sweden)

    Nemliher, Jüri

    2006-06-01

    Full Text Available Sequences of the Leetse Formation were studied in order to find out the conodont biozonation, grain-size distribution, and glauconite mineral properties and their variations along the North Estonian Klint. On the basis of the conodont zonation of the Saka section, combined with earlier data, it was found that the Leetse Formation belongs to the Paroistodus proteus, Prioniodus elegans, and Oepikodus evae zones of various thickness and completeness along the North Estonian Klint. The Pr. elegans Zone of the Saka section was found to be remarkably complete and correlate well with equivalent intervals of sections in the St. Petersburg Region. Poorly lithified glauconitic sandstones of the Leetse Formation vary lithologically vertically as well as laterally. The Leetse Formation in the west has been repeatedly redeposited and is depleted in suspended fraction, while in the east it is more homogeneous and represents continuous shallow-water conditions. Glauconite is represented by a potassium-rich variety (about 9% K2O and most likely forms at least two discrete modifications. Laterally, glauconite of the Leetse Formation in the western part of the klint contains less K than that of the eastern part, indicating faster sedimentation. The d(001 value of glauconite diminishes upwards in the sequence, indicating acceleration of the sedimentation rate.

  10. Standard test method for determination of reference temperature, to, for ferritic steels in the transition range

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2011-01-01

    1.1 This test method covers the determination of a reference temperature, To, which characterizes the fracture toughness of ferritic steels that experience onset of cleavage cracking at elastic, or elastic-plastic KJc instabilities, or both. The specific types of ferritic steels (3.2.1) covered are those with yield strengths ranging from 275 to 825 MPa (40 to 120 ksi) and weld metals, after stress-relief annealing, that have 10 % or less strength mismatch relative to that of the base metal. 1.2 The specimens covered are fatigue precracked single-edge notched bend bars, SE(B), and standard or disk-shaped compact tension specimens, C(T) or DC(T). A range of specimen sizes with proportional dimensions is recommended. The dimension on which the proportionality is based is specimen thickness. 1.3 Median KJc values tend to vary with the specimen type at a given test temperature, presumably due to constraint differences among the allowable test specimens in 1.2. The degree of KJc variability among specimen types i...

  11. Wild Estonian and Russian sea trout (Salmo trutta) in Finnish coastal sea trout catches: results of genetic mixed-stock analysis.

    Science.gov (United States)

    Koljonen, Marja-Liisa; Gross, Riho; Koskiniemi, Jarmo

    2014-12-01

    For responsible fisheries management of threatened species, it is essential to know the composition of catches and the extent to which fisheries exploit weak wild populations. The threatened Estonian, Finnish and Russian sea trout populations in the Gulf of Finland are targets of mixed-stock fisheries. The fish may originate from rivers with varying production capacities, from different countries, and they may also have either a wild or hatchery origin. In order to resolve the composition of Finnish coastal sea trout catches, we created a standardized baseline dataset of 15 DNA microsatellite loci for 59 sea trout populations around the Gulf of Finland and tested its resolution for mixed-stock analysis of 1372 captured fish. The baseline dataset provided sufficient resolution for reliable mixture analysis at regional group level, and also for most of the individual rivers stocks. The majority (76-80%) of the total catch originated from Finnish sea trout populations, 6-9% came from Russian and 12-15% from Estonian populations. Nearly all Finnish trout in the catch were of hatchery origin, while the Russian and Estonian trout were mostly of wild origin. The proportion of fish in the Finnish catches that originated from rivers with natural production was at least one fifth (22%, 19-23%). Two different spotting patterns were observed among the captured trout, with a small and sparsely spotted form being markedly more common among individuals of Russian (28%) and Estonian origin (22%) than among fish assigned to a Finnish origin (0.7%). © 2015 The Authors.

  12. Reference values for the transformed Van Lieshout hand function test for tetraplegia.

    Science.gov (United States)

    Spooren, A I F; Arnould, C; Smeets, R J E M; Snoek, G; Seelen, H A M

    2013-10-01

    Longitudinal cohort study. Previously, the Van Lieshout hand function test for tetraplegia (short form)(VLT-SF) has been transformed into an interval scale (r_VLT-SF) using the Rasch analysis, thereby fulfilling the requirements of an objective measurement. The present study aims (1) to transform r_VLT-SFlogit scores (r_VLT-SFlogit) into 0-100 scores (r_VLT-SF100) in order to facilitate communication amongst its users and (2) to describe r_VLT-SF100 reference values in order to refine the prediction of upper extremity skilled performance in persons with tetraplegia. Eight Dutch rehabilitation centres. The VLT-SF data of tetraplegic patients from eight Dutch rehabilitation centres, gathered at the start of the active rehabilitation (t1), 3 months after t1 (t2) and at the time of discharge (t3), have been used. The r_VLT-SF100 total score for t1 and t3 were computed, anchored on the data for t2. Reference values (medians and interquartiles) for different subgroups were calculated at different moments during the rehabilitation. Data at t1 (n=64), t2 (n=73) and t3 (n=69) were used. The r_VLT-SFlogit scores (-4.78-6.32) were transformed into r_VLT-SF100 (0-100) at t2. Reference values were established for persons with motor complete or incomplete lesions with either a high (C1-C6) or a low (C7-T1) lesion level at t1, t2 and t3. Significant differences (P<0.025) in r_VLT-SF100 were found for most subgroups and different time intervals. The r_VLT-SFlogit scores were converted into r_VLT-SF100 scores, and reference values of the r_VLT-SF100 have been established for different subgroups of tetraplegic patients at different stages during rehabilitation. The r_VLT-SF100 has been proven to be able to detect improvement over time.

  13. Human papillomavirus testing for triage of women referred because of abnormal smears: a decision analysis considering outcomes and costs

    NARCIS (Netherlands)

    Meerding, Willem Jan; van Ballegooijen, Marjolein; Burger, Matthé P. M.; van den Akker-van Marle, M. Elske; Quint, Wim G. V.; Habbema, J. Dik F.

    2002-01-01

    The objective of this article was to evaluate the utility of high-risk human papillomavirus (HR-HPV) testing for triage of women referred for colposcopy because of abnormal smears. We considered women with persistent mild or moderate dyskaryosis and women with severe dyskaryosis who were referred

  14. Rahvusliku ajaloo tõlgendusi eesti draamas ja teatris 1970.–1980. aastatel. Interpretations of National History in Estonian Drama and Theatre in the 1970s–1980s

    Directory of Open Access Journals (Sweden)

    Piret Kruuspere

    2012-04-01

    Full Text Available According to theatre scholar Freddie Rokem, theatre portraying or performing historical events is seeking to overcome both the separation and the exclusion from the past, as well as ’striving to create a community where the events from this past will matter again’. This article covers the topic of interpretations of national history in Estonian theatre and in original dramaturgy during the Soviet era, with the focus on aspects like national self-reflection and the relationship to the common past. The main focus is on the 1970s, with examples from Rein Saluri’s, Mati Unt’s and Jaan Kaplinski’s drama productions. During the period in question, re-tellings of national history on Estonian theatre stages were clothed in metaphors, allusions and secret codes – Aesopian language. Within the Soviet cultural context, I analyse if and to what extent theatre of the time displayed resistance, political theatre or social allegory. Theatre was also connected with the principle of playing or playfulness, which on one hand indicates national resistance, national endurance, and a certain survival strategy, but on the other hand indicates the Estonian as being an involuntary homo ludens – the Playing Man, who through various enforced roles is trying to adjust to the whirlwinds of history. Saluri’s first play, the intellectual drama Külalised (The Guests, opens with an allusion to a drama classic the world over, William Shakespeare’s Hamlet, adding a powerful national-symbolic background to the play. The role-play which permeates and structures the play (The Host–The Guest however, displays allegorical references to changes in the status and self-image of Estonians. In Unt’s play Peaproov (Dress Rehearsal, the principle of playing/acting sheds ironic light on the makers of an historical film and their readiness to create superficially flashy interpretations at any cost: this take acts as an estranging and generalising reflection in a context

  15. [Marge Rennit. Eesti muuseumid / Estonian museums] / Tapio Mäkeläinen

    Index Scriptorium Estoniae

    Mäkeläinen, Tapio

    2009-01-01

    Tutvustus: Eesti muuseumid = Estonian museums / [Eesti Muuseumiühing ; koostaja Marge Rennit ; tõlkija Tiina Mällo ; toimetaja Ivi Tammaru ; eessõna: Piret Õunapuu ; kujundaja Marek Allvee]. Tallinn : Oomen, 2008

  16. IS THE ESTONIAN MODEL APPLICABLE TO ROMANIAN ECONOMY IN ADOPTING THE EURO?

    National Research Council Canada - National Science Library

    I Radu; M-L Ciupac-Ulici; A Petcu

    2013-01-01

    .... Since the Euro adoption process is a controversial one, in this paper the authors aim to express their concerns regarding the major changes driven from other member states of the Euro Area, i.e. the Estonian model...

  17. SAS paneb Estonian Airi kiirmüüki / Gert D. Hankewitz

    Index Scriptorium Estoniae

    Hankewitz, Gert D.

    2009-01-01

    Majandusraskustes lennufirma SAS kavatseb loobuda osalustest kõigis lennufirmades, mis ei sobi kokku nende uue tegevuskavaga. Majandus- ja kommunikatsiooniminister Juhan Parts arvab, et riik peaks leidma Estonian Airile kodumaised partnerid

  18. Russian-Estonian Economic and Investment Cooperation During the Crisis: Dynamics and Possibilities

    National Research Council Canada - National Science Library

    Nevskaya Anastasia

    2015-01-01

    The article deals with the development in Russian-Estonian relations during the crises of 2007 and 2014, taking into consideration the balance between political and economic factors in the decision...

  19. Estonian Air andis Berliini liinil loobumisvõidu / Ralf-Martin Soe

    Index Scriptorium Estoniae

    Soe, Ralf-Martin

    2006-01-01

    Estonian Air sulgeb 2007. aasta jaanuarist Tallinn-Berliin liini, mille võtab üle odavlennufirma easyJet. Diagramm: Lennureisijate arv Tallinn-Berliin. Vt. samas: easyJet kehv alternatiiv. Kommenteerivad Rein Loik ja Mati Feldmann

  20. Comparative assay of fluorescent antibody test results among twelve European National Reference Laboratories using various anti-rabies conjugates

    DEFF Research Database (Denmark)

    Robardet, E.; Andrieu, S.; Rasmussen, Thomas Bruun

    2013-01-01

    Twelve National Reference Laboratories (NRLs) for rabies have undertaken a comparative assay to assess the comparison of fluorescent antibody test (FAT) results using five coded commercial anti-rabies conjugates (Biorad, Bioveta, Fujirebio, Millipore, and SIFIN conjugates). Homogenized positive...

  1. Reference ranges for thromboelastography (TEG®) and traditional coagulation tests in term parturients undergoing caesarean section under spinal anaesthesia

    National Research Council Canada - National Science Library

    Macafee, B; Campbell, J. P; Ashpole, K; Cox, M; Matthey, F; Acton, L; Yentis, S. M

    2012-01-01

    There has been little published work defining ‘normal’ thromboelastography (TEG ® ) values in healthy parturients, and few large studies defining reference ranges for traditional coagulation tests in this patient group...

  2. [Reference values for the blood coagulation tests in Mexico: usefulness of the pooled plasma from blood donors].

    Science.gov (United States)

    Calzada-Contreras, Adriana; Moreno-Hernández, Manuel; Castillo-Torres, Noemi Patricia; Souto-Rosillo, Guadalupe; Hernández-Juárez, Jesús; Ricardo-Moreno, María Tania; Sánchez-Fernández, Maria Guadalupe de Jesús; García-González, América; Majluf-Cruz, Abraham

    2012-01-01

    The blood coagulation system maintains the blood in a liquid state and bleeding and thrombosis are the manifestations of its malfunction. Blood coagulation laboratory evaluates the physiology of this system. To establish both, the reference values for several tests performed at the blood coagulation laboratory as well as the utility of the pooled plasma to perform these assays. MATERIAL AND: In this descriptive, cross-sectional, randomized study, we collected plasma from Mexican Mestizos. Each pooled plasma was prepared with the plasma from at least 20 blood donors. We performed screening and special tests and the Levey-Jennings graphs were built and interpreted after each pass. Results of the tests were analyzed and their distribution was established using the Kolmogorov-Smirnov test. To establish the reference values we used 95% confidence intervals. We collected 72 pooled plasmas. The distribution for PT, APTT, and TT tests was abnormal. Although the PT test showed a bimodal distribution it was normal for factor VII. The reference values for the hemostatic, anticoagulant, and fibrinolytic factors were different from those suggested by the manufacturers. We established the reference values for the blood coagulation tests in the adult Mexican population. We have shown that the pooled plasma must be used for the screening tests. We suggest that each clinical laboratory should establish its own reference values (at least for the screening tests). To reach this objective, we encourage the use of the pooled plasma.

  3. Alternative buffer material. Status of the ongoing laboratory investigation of reference materials and test package 1

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Daniel [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Dueck, Ann; Nilsson, Ulf; Olsson, Siv; Sanden, Torbjoern [Clay Technology AB, Lund (Sweden); Lydmark, Sara; Jaegerwall, Sara; Pedersen, Karsten [Microbial Analytics Sweden AB, Moelnlycke (Sweden); Hansen, Staffan [LTH Lund Univ., Lund (Sweden)

    2011-07-15

    Bentonite clay is part of the Swedish KBS-3 design of final repositories for high level radioactive waste. Wyoming bentonite with the commercial name MX-80 (American Colloid Co) has long been the reference for buffer material in the KBS-3 concept. Extending the knowledge base of alternative buffer materials will make it possible to optimize regarding safety, availability and cost. For this reason the field experiment Alternative Buffer Material (ABM) was started at Aespoe Hard Rock Laboratory during 2006. The experiment includes three medium-scale test packages, each consisting of a central steel tube with heaters, and a buffer of compacted clay. Eleven different clays were chosen for the buffers to examine effects of smectite content, interlayer cations and overall iron content. Also bentonite pellets with and without additional quartz are being tested. The buffer in package 1 had been subjected to wetting by formation water and heating for more than two years (at 130 deg C for {approx} 1 year) when it was retrieved and analyzed. The main purposes of the project were to characterise the clays with respect to hydro-mechanical properties, mineralogy and chemical composition and to identify any differences in behaviour or long term stability. The diversity of clays and the heater of steel also make the experiment suitable for studies of iron-bentonite interactions. This report concerns the work accomplished up to now and is not to be treated as any final report of the project.

  4. Russian-Estonian economic and investment cooperation during the crisis: dynamics and possibilities

    OpenAIRE

    Nevskaya Anastasia

    2015-01-01

    The article deals with the development in Russian-Estonian relations during the crises of 2007 and 2014, taking into consideration the balance between political and economic factors in the decision-making by Estonian government. A number of special aspects, trends and problems in trade and investment ties are detected. The aim of the study is to uncover key motivation behind the actions of both Russia and Estonia, to identify the drivers for economic and political development in the region, a...

  5. 4-Second Exercise Test: Reference Values for Ages 18-81 Years.

    Science.gov (United States)

    Araújo, Claudio Gil; Castro, Claudia Lucia Barros de; Franca, João Felipe; Ramos, Plínio Santos

    2015-05-01

    Physiological reflexes modulated primarily by the vagus nerve allow the heart to decelerate and accelerate rapidly after a deep inspiration followed by rapid movement of the limbs. This is the physiological and pharmacologically validated basis for the 4-s exercise test (4sET) used to assess the vagal modulation of cardiac chronotropism. To present reference data for 4sET in healthy adults. After applying strict clinical inclusion/exclusion criteria, 1,605 healthy adults (61% men) aged between 18 and 81 years subjected to 4sET were evaluated between 1994 and 2014. Using 4sET, the cardiac vagal index (CVI) was obtained by calculating the ratio between the duration of two RR intervals in the electrocardiogram: 1) after a 4-s rapid and deep breath and immediately before pedaling and 2) at the end of a rapid and resistance-free 4-s pedaling exercise. CVI varied inversely with age (r = -0.33, p age were similar for men and women (p > 0.05). Considering the heteroscedasticity and the asymmetry of the distribution of the CVI values according to age, we chose to express the reference values in percentiles for eight age groups (years): 18-30, 31-40, 41-45, 46-50, 51-55, 56-60, 61-65, and 66+, obtaining progressively lower median CVI values ranging from 1.63 to 1.24. The availability of CVI percentiles for different age groups should promote the clinical use of 4sET, which is a simple and safe procedure for the evaluation of vagal modulation of cardiac chronotropism.

  6. Media representation of feminism in estonian journalism : A qualitative analysis over the newsarticles of Eesti Peavaleht

    OpenAIRE

    Berendsen, Eva

    2015-01-01

    Estonian society, as a short history of gender studies, and the introduction of the termsfeminism or feminist, only started to appear in media during the second half of the 1990s.Nevertheless, the public opinion and attitudes about feminism among Estonian society arenot clear, while sexual discrimination is still a frequent occurrence (Estonia, 2013). Thearchive of the biggest Estonian daily newspaper Eesti Paevaleht includes articles aboutfeminism written in the last 15 years that will be an...

  7. Using micro-contexts to describe a writing process in Estonian as a second language across proficiency levels

    Directory of Open Access Journals (Sweden)

    Olga Pastuhhova

    2015-04-01

    Full Text Available This paper aims to describe the writing process of native Russian‑speaking students in Estonian as a second language. 34 participants were given the assignment of writing a text in the L2. The written texts were then rated as being at levels from A2 to C1 according to the Common European Framework of Reference for Languages (CEFR. The data were collected by computer keystroke logging and analysed based on the concept of a ‘micro-context’. Micro-contexts were analysed according to their frequency and duration and were compared across proficiency levels. The results show that writing in the L2 is not a smooth process. The longest transitions in micro-contexts reveal that the most cognitive effort is made between paragraphs and sentences and when deletions are involved. The growing number of consecutive deletions demonstrates that even with developing proficiency, the linear production text is subject to constant revision, correction and modification.

  8. SU-F-J-180: A Reference Data Set for Testing Two Dimension Registration Algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Dankwa, A; Castillo, E; Guerrero, T [William Beaumont Hospital, Rochester Hills, MI (United States)

    2016-06-15

    Purpose: To create and characterize a reference data set for testing image registration algorithms that transform portal image (PI) to digitally reconstructed radiograph (DRR). Methods: Anterior-posterior (AP) and Lateral (LAT) projection and DRR image pairs from nine cases representing four different anatomical sites (head and neck, thoracic, abdominal, and pelvis) were selected for this study. Five experts will perform manual registration by placing landmarks points (LMPs) on the DRR and finding their corresponding points on the PI using computer assisted manual point selection tool (CAMPST), a custom-made MATLAB software tool developed in house. The landmark selection process will be repeated on both the PI and the DRR in order to characterize inter- and -intra observer variations associated with the point selection process. Inter and an intra observer variation in LMPs was done using Bland-Altman (B&A) analysis and one-way analysis of variance. We set our limit such that the absolute value of the mean difference between the readings should not exceed 3mm. Later on in this project we will test different two dimension (2D) image registration algorithms and quantify the uncertainty associated with their registration. Results: Using one-way analysis of variance (ANOVA) there was no variations within the readers. When Bland-Altman analysis was used the variation within the readers was acceptable. The variation was higher in the PI compared to the DRR.ConclusionThe variation seen for the PI is because although the PI has a much better spatial resolution the poor resolution on the DRR makes it difficult to locate the actual corresponding anatomical feature on the PI. We hope this becomes more evident when all the readers complete the point selection. The reason for quantifying inter- and -intra observer variation tells us to what degree of accuracy a manual registration can be done. Research supported by William Beaumont Hospital Research Start Up Fund.

  9. PRIMITIVE-BASED 3D BUILDING RECONSTRUCTION METHOD TESTED BY REFERENCE AIRBORNE DATA

    Directory of Open Access Journals (Sweden)

    W. Zhang

    2012-07-01

    Full Text Available Airborne LiDAR data and optical imagery are two datasets used for 3D building reconstruction. By study of the complementarities of these two datasets, we proposed a primitive-based 3D building reconstruction method, which can use LiDAR data and optical imagery at the same time. The proposed method comprises following steps: (1 recognize primitives from LiDAR point cloud and roughly measure primitives’ parameters as initial values, and (2 select primitives' features on the imagery, and (3 optimize primitives' parameters by the constraints of LiDAR point cloud and imagery, and (4 represent 3D building model by these optimized primitives. Compared with other model-based or CSG-based methods, the proposed method has some advantages. It is simpler, because it only uses the most straightforward features, i.e. planes of LiDAR point cloud and points of optical imagery. And it can tightly integrate LiDAR point cloud and optical imagery, that is to say, all primitives' parameters are optimized with all constraints in one step. Recently, an ISPRS Test Project on Urban Classification and 3D Building Reconstruction was launched, two datasets both with airborne LiDAR data and images are provided. The proposed method was applied to Area 3 of Dataset 1 Vaihingen, in which there are some buildings with plane roofs or gable roofs. The organizer of this test project evaluated the submitted reconstructed 3D model using reference data. The result shows the feasibility of the proposed 3D building reconstruction method.

  10. Eesti Ja Vene Opilased Soome Kaandsona Mitmuse Vormide Moodustajatena: Testi Tulemuste Statistiline Ulevaade (Learning Finnish as a Second Language in Estonia: Results of a Test).

    Science.gov (United States)

    Kaivapalu, Annekatrin

    This report is based on a test that was arranged in April and May of 1997 among first- and second-year students at Tallinn Pedagogical University who studied the Finnish language as a general subject and among the students of the eleventh and twelfth grades in some Estonian secondary schools. There were among 105 Estonians and 25 Russians among…

  11. Musical Manifestations of Textual Patterning in Estonian Regilaul

    Directory of Open Access Journals (Sweden)

    Janika Oras

    2011-05-01

    Full Text Available The article analyses the marking of song text patterns by means of musical devices in the performances of Estonian regilaul. The article examines which variants of musical rhythm and melodic contour are preferred by four singers in their performance of verses that have different functions within the song structure. In both the text and the musical rhythm, a greater number of syllables, and the attendant changes in musical rhythm, mark the verses that have an initiating function and which communicate entirely new information. In performing such verses, rather than the extension verses of parallelism groups or verse repetitions, in the short melodies with narrow pitch range, the singers prefer more "intense" variants of melody contours in which the higher notes of the scale are predominantly used. In two-line melodies, the singer's patterning of the song text is largely determined by the musical logic, attempting to align the beginnings of the melodic strophes and verse groups.

  12. Musical Manifestations of Textual Patterning in Estonian Regilaul

    Directory of Open Access Journals (Sweden)

    Janika Oras

    2010-12-01

    Full Text Available The article analyses the marking of song text patterns by means of musical devices in the performances of Estonian regilaul. The article examines which variants of musical rhythm and melodic contour are preferred by four singers in their performance of verses that have different functions within the song structure. In both the text and the musical rhythm, a greater number of syllables, and the attendant changes in musical rhythm, mark the verses that have an initiating function and which communicate entirely new information. In performing such verses, rather than the extension verses of parallelism groups or verse repetitions, in the short melodies with narrow pitch range, the singers prefer more "intense" variants of melody contours in which the higher notes of the scale are predominantly used. In two-line melodies, the singer's patterning of the song text is largely determined by the musical logic, attempting to align the beginnings of the melodic strophes and verse groups.

  13. Early vocabulary in full term and preterm Estonian children.

    Science.gov (United States)

    Schults, Astra; Tulviste, Tiia; Haan, Elis

    2013-09-01

    Preterm birth is considered to be a high risk factor for child development and early vocabulary can be used as an indicator for later development. The aim of the present study is to compare the size of early vocabulary, proportional use of different word categories, and mean length of utterance (henceforth MLU) of preterm and full term children. The sample consisted of 40 preterm (corrected ages 16-25 months) and two matched groups of full term children. First full term group consisted of 120 children who were matched by age and gender. Second full term group consisted of 109 children who were matched by age, gender and size of productive vocabulary. The data for this study were gathered using the Estonian adaptation of MacArthur-Bates Communicative Development Inventory: Words and Sentences. Full term children who were matched by age and gender had larger vocabulary as compared to the preterm children's vocabulary (U = 1758.5, p = 0.01). Poisson regression yielded that age, gender, and preterm birth explained significantly the variance in the vocabulary size. Poisson regressions showed that all three variables explained significantly variance in proportional use of social terms and predicates. Age had significant effect for proportional use of common nouns. Age and preterm birth had a significant effect on the proportional use of function words. MLU was shorter in preterm than in full term children (U = 1125.0, p = 0.002). Estonian preterm children's vocabulary is slightly smaller than full term children's vocabulary. There is a difference in the proportions of word categories used, as preterm children use more social terms, and less predicates, and function words. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Exploration of quantitative sensory testing in latent trigger points and referred pain areas

    DEFF Research Database (Denmark)

    Ambite-Quesada, Silvia; Arías-Buría, José L.; Courtney, Carol A.

    2017-01-01

    over the TrP, in the referred pain area, and in the respective contra-lateral mirror areas. A multilevel mixed-model ANOVA with site (TrP, referred pain area) and side (real or contra-lateral) as within-subjects factors and gender as between-subjects factor was conducted. RESULTS: No significant...

  15. Evaluation of tests for antibodies against bovine herpesvirus 1 performed in national reference laboratories in Europe

    NARCIS (Netherlands)

    Kramps, J.A.; Banks, M.; Beer, M.; Kerkhofs, P.; Perrin, M.; Wellenberg, G.J.; Oirschot, van J.T.

    2004-01-01

    Sets of serum and milk samples were collected from various countries and prepared, lyophilised and distributed by 1 laboratory to 12 reference laboratories in Europe. The serum sets contained the three European bovine herpesvirus 1 (BHV1) reference serum samples (EU1, EU2 and EU3), serum samples

  16. Development of internal forest soil reference samples and testing of digestion methods

    Science.gov (United States)

    J.E. Hislop; J.W. Hornbeck; S.W. Bailey; R.A. Hallett

    1998-01-01

    Our research requires determinations of total elemental concentrations of forest soils. The lack of certified forest soil reference materials led us to develop internal reference samples. Samples were collected from three soil horizons (Oa, B, and C) at three locations having forested, acidic soils similar to those we commonly analyze. A shatterbox was used to...

  17. Sodium chloride as a reference substance for the three growth endpoints used in the Lemna minor L. (1753 test

    Directory of Open Access Journals (Sweden)

    Aline Andrade Godoy

    2017-01-01

    Full Text Available Lemna sp. growth inhibition test standardized protocols suggest the use of compounds such as 3,5-dichlorophenol as reference substances for checking the test organism’s sensitivity routinely. However, this and other recommended chemicals present risks to human health and to the environment. Sodium chloride (NaCl appears as a less toxic alternative reference substance which has been successfully used in routine ecotoxicological tests. However, the evaluation of this compound in multiple growth endpoints used in the L. minor test, which is required for recommending it as a reference substance for this test organism, has not yet been reported. In the present study, NaCl was tested with L. minor for the growth endpoints frond number, total frond area and fresh weight. Results showed acceptable sensitivity and reproducibility (coefficient of variance < 15.0% for all three of the measured endpoints. Statistically significant differences were observed between the EC50 values calculated based on the three endpoints (p < 0.05. Total frond area was the most sensitive one, with average EC50 value of 2742.80 ± 245.7 mg L-1. It was anticipated that NaCl can be a suitable alternative reference substance and that total frond area should be the endpoint of choice for sensitivity toxicity tests using NaCl.

  18. Prolonged storage-induced changes in haematology parameters referred for testing

    Directory of Open Access Journals (Sweden)

    Elise Schapkaitz

    2015-05-01

    Full Text Available Background: Referral of samples for the work-up of haematological disorders from remote laboratories can result in a delay in analysis.Objective: The stability of the full blood count (FBC, differential count (DIFF, reticulocyte and peripheral blood smear (PBS morphology during extended storage was evaluated.Methods: Forty blood samples stored in ethylenediaminetetraacetic acid (EDTA were analysed on an ADVIA® 120 haematology analyser. The samples (25% abnormal; 75% normal were stored at room temperature (RT and at 4 °C – 8 °C. Analysis of samples stored at RT was performed every 12 hours for two days. Analysis of samples stored at 4 °C – 8 °C was performed at 12 hours and subsequently every 24 hours for seven days.Results: FBC parameters (red cell count, haemoglobin and DIFF parameters (percentages of basophils, lymphocytes and monocytes were stable for at least 48 hours when stored at RT. Platelets were only stable for 12 hours and the white cell count was stable for 36 hours when stored at RT. Storing samples at 4 °C – 8 °C significantly increased the stability of most parameters, in particular, mean cell volume and percentage of reticulocytes. However, DIFF parameters were associated with lower stability at 4 °C – 8 °C. PBS morphology was compromised prior to 12 hours whether stored at RT or at 4 °C – 8 °C.Conclusion: This study provides evidence that blood samples stored in EDTA at 4 °C – 8 °C for seven days are suitable for testing on the ADVIA® 120 analyser for the FBC and percentage of reticulocyte parameters. However, storage at 4 °C – 8 °C is not a solution for samples referred for DIFF and PBS morphology review.

  19. Quality specifications for the extra-analytical phase of laboratory testing: Reference intervals and decision limits.

    Science.gov (United States)

    Ceriotti, Ferruccio

    2017-07-01

    Reference intervals and decision limits are a critical part of the clinical laboratory report. The evaluation of their correct use represents a tool to verify the post analytical quality. Four elements are identified as indicators. 1. The use of decision limits for lipids and glycated hemoglobin. 2. The use, whenever possible, of common reference values. 3. The presence of gender-related reference intervals for at least the following common serum measurands (besides obviously the fertility relate hormones): alkaline phosphatase (ALP), alanine aminotransferase (ALT), creatine kinase (CK), creatinine, gamma-glutamyl transferase (GGT), IgM, ferritin, iron, transferrin, urate, red blood cells (RBC), hemoglobin (Hb) and hematocrit (Hct). 4. The presence of age-related reference intervals. The problem of specific reference intervals for elderly people is discussed, but their use is not recommended; on the contrary it is necessary the presence of pediatric age-related reference intervals at least for the following common serum measurands: ALP, amylase, creatinine, inorganic phosphate, lactate dehydrogenase, aspartate aminotransferase, urate, insulin like growth factor 1, white blood cells, RBC, Hb, Hct, alfa-fetoprotein and fertility related hormones. The lack of such reference intervals may imply significant risks for the patients. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  20. Reference Values for the Six-Minute Walk Test in Healthy Children and Adolescents: a Systematic Review

    Directory of Open Access Journals (Sweden)

    Lucas de Assis Pereira Cacau

    Full Text Available Abstract Objective: The aim of the study is to compare the available reference values and the six-minute walk test equations in healthy children/adolescents. Our systematic review was planned and performed in accordance with the PRISMA guidelines. We included all studies that established reference values for the six-minute walk test in healthy children/adolescents. Methods: To perform this review, a research was performed in PubMed, EMBASE (via SCOPUS and Cochrane (LILACS, Bibliographic Index Spanish in Health Sciences, Organization Collection Pan-American Health Organization, Publications of the World Health Organization and Scientific Electronic Library Online (SciELO via Virtual Health Library until June 2015 without language restriction. Results: The initial research identified 276 abstracts. Twelve studies met the inclusion criteria and were fully reviewed and approved by both reviewers. None of the selected studies presented sample size calculation. Most of the studies recruited children and adolescents from school. Six studies reported the use of random samples. Most studies used a corridor of 30 meters. All studies followed the American Thoracic Society guidelines to perform the six-minute walk test. The walked distance ranged 159 meters among the studies. Of the 12 included studies, 7 (58% reported descriptive data and 6 (50% established reference equation for the walked distance in the six-minute walk test. Conclusion: The reference value for the six-minute walk test in children and adolescents ranged substantially from studies in different countries. A reference equation was not provided in all studies, but the ones available took into account well established variables in the context of exercise performance, such as height, heart rate, age and weight. Countries that did not established reference values for the six-minute walk test should be encouraged to do because it would help their clinicians and researchers have a more precise

  1. The use of different reference foods in determining the glycemic index of starchy and non-starchy test foods

    Science.gov (United States)

    2014-01-01

    Background Glycemic index (GI) is intended to be a property of food but some reports are suggestive that GI is influenced by participant characteristics when glucose is used as a reference. Objective To examine the influence of different reference foods on observed GI. Design The GIs of five varieties of rice and a sugary beverage (LoGiCane™) were tested in 31 European and 32 Chinese participants using glucose or jasmine rice as reference foods. The GIs of two ready-to-eat breakfast cereals (Kellogg’s cornflakes and Sustain) were tested in 20 younger and 60 older people using glucose or Sustain as reference foods. Results The GIs of rice tended to be higher in the Chinese compared with the Europeans when glucose was used as a reference (jasmine 80 vs 68, P = 0.033; basmati 67 vs 57, P = 0.170; brown 78 vs 65, P = 0.054; Doongara 67 vs 55, P = 0.045; parboiled 72 vs 57, P = 0.011). There were no between-group differences in GI when jasmine rice was the reference. The GIs of breakfast cereals tended to be lower in younger compared with older groups (cornflakes 64 vs 81, P = 0.008; Sustain 56 vs 66, P = 0.054). There was no between-group difference in the GI of cornflakes when Sustain was the reference (cornflakes 115 vs 120, P = 0.64). There was no ethnic difference in GI when glucose was the reference for another sugary food (LoGiCane™ 60 vs 62; P = 0.69). Conclusions A starchy reference may be more appropriate than a glucose beverage when attempting to derive universally applicable GI values of starchy foods. Trial registration The Chinese/European trial is registered with the Australian New Zealand Clinical Trials Registry as ACTRN12612000519853. PMID:24885045

  2. Kolm Eesti Robinsoni: Daniel Defoe romaan eesti tõlkes / Three Estonian Robinsons: Daniel Defoe’s Novel in Estonian Translation

    Directory of Open Access Journals (Sweden)

    Ene-Reet Soovik

    2012-06-01

    Full Text Available The article discusses three Estonian translations of Daniel Defoe’s Robinson Crusoe into Estonian with the focus on the completeness of the translated texts and the characterisation given to these in paratextual information. While there are several translations and versions of the tex t available in E stonian that have either used a mediating language or do not proceed directly from Defoe’s novel, three editions explicitly list Defoe’s English-language Robinson Crusoe as their source text. These are Rudolf Sirge’s translation from 1950 and two editions translated by Valter Rummel that appeared in 1984 (reprinted in 2001 and 2007, respectively. The article sets out to discover the main differences between the three editions and the possible reasons that may have triggered their publication in Estonia at those particular times. In order to approach the issues, a general framework derived from descriptive translation studies is employed with an emphasis on Gideon Toury’s chrestomatic treatment of translation norms. Thus an attempt is made to detect the preliminary translational norms regarding translation policy, particularly the choice of texts to be translated, as well as the matricial norms that concern the fullness of the translated text and are part of operational norms manifested in the translator’s decisions which, in two of the cases at hand, may also have been decisions made by the editor or the censor. Rudolf Sirge’s translation appeared at a time when Estonia had fairly recently been incorporated into the Soviet Union and there was a lack of children’s literature ideologically appreciated by the regime. This may account for the packaging of the book as a work with a strong didactic bent, while its primary audience was taken to be children and young adults for whom the protagonist served as an example of a hard-working and tenacious hero to be emulated by young Soviets. The target text has been considerably shortened as

  3. King-Devick Test reference values and associations with balance measures in high school American football players.

    Science.gov (United States)

    Alsalaheen, B; Haines, J; Yorke, A; Diebold, J

    2016-02-01

    The King-Devick test appears to be a promising tool in screening for concussions. However, limited evidence exists on the baseline associations between the K-D test and age and baseline screening tools used after concussion. Additionally, there are no published reference values for the K-D test in high school football players. The K-D test, the Balance Error Scoring System, and the Limits of Stability (LOS) test were administered to 157 high school football players. Additionally, a subsample of 62 participants completed the test twice to examine the reliability of K-D test. There was no relationship between the K-D test and the BESS, or the reaction time and directional control of LOS test. Students aged between 16 and 18 years demonstrated faster K-D test performance compared to students between 13 and 15 years of age. However, there was no association between K-D test and history of concussion. The reliability of the K-D test was (ICC2,1 = 0.89), and the minimal detectable change was 6.10 s. Normative reference values for high school football players are presented in this study. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Anodonta imbecillis copper sulfate reference toxicant/food test, Clinch River - Environmental Restoration Program (CR-ERP)

    Energy Technology Data Exchange (ETDEWEB)

    Simbeck, D.J.

    1997-06-01

    Reference toxicant testing using juvenile freshwater mussels was conducted as part of the CR-ERP biomonitoring study of Clinch River sediments to assess the sensitivity of test organisms and the overall performance of the test. Tests were conducted using moderately hard synthetic water spiked with known concentrations of copper as copper sulfate. Two different foods, phytoplankton and YCT-Selenastrum (YCT-S), were tested in side by side tests to compare food quality. Toxicity testing of copper sulfate reference toxicant was conducted from July 6-15, 1993. The organisms used for testing were juvenile fresh-water mussels (Anodonta imbecillis). Results from this test showed LC{sub 50} values of 0.97 and 0.84 mg Cu/L for phytoplankton and YCT-S, respectively. Previously obtained values for phytoplankton tests are 2.02 and 1.12 mg Cu/L. Too few tests have been conducted with copper as the toxicant to determine a normal range of values. Although significant reduction in growth, compared to the phytoplankton control, was seen in all treatments, including the YCT-S Control, the consequence of this observation has not been established. Ninety-day testing of juvenile mussels exhibited large variations in growth within treatment and replicate groups.

  5. The Effect of the 2008 War on Estonian Public Confidence in International Organisations: A Mixed Methods Study

    NARCIS (Netherlands)

    Moes, Jeroen; Melchior, Inge; Gugushvili, Alexi

    2014-01-01

    When the so-called 5 Day War between Russia and Georgia occurred in the summer of 2008, the Estonian public reaction was especially passionate. Two major explanations stem from the strong identification of Estonians with the situation of Georgia (post-Soviet state, small country, Russian

  6. Jäätmetega kimpus Estonian Cell annab muda põldudele kompostiks / Ulvar Käärt

    Index Scriptorium Estoniae

    Käärt, Ulvar, 1982-

    2007-01-01

    Kundas asuv Estonian Celli tehas jagab ümberkaudsetele talunikele jäätmetest lahtisaamiseks kompostimissegu. Seadused ei sätesta, kuidas Estonian Cellis tekkivaid jäätmeid töödelda. Kommenteerib Peeter Eek: Aasta läbi ei saa muda põllule viia

  7. Musical Practices and Methods in Music Lessons: A Comparative Study of Estonian and Finnish General Music Education

    Science.gov (United States)

    Sepp, Anu; Ruokonen, Inkeri; Ruismäki, Heikki

    2015-01-01

    This article reveals the results of a comparative study of Estonian and Finnish general music education. The aim was to find out what music teaching practices and approaches/methods were mostly used, what music education perspectives supported those practices. The data were collected using questionnaires and the results of 107 Estonian and 50…

  8. Reference markers in computer aided orthopaedic surgery: rotational stability testings and clinical implications.

    Science.gov (United States)

    Kendoff, Daniel; Gardner, Michael J; Krettek, Christian; Hüfner, Tobias; Citak, Musa

    2008-06-01

    Navigation procedures rely on the stability of the reference arrays (RA) fixed to the bony anatomy. The risk of inadvertent collision and unnoticed movements of the RA may occur, and limb movements might also provocate collisions. Consequently, relevant measurements failures during the navigated procedure might occur and reduce the overall precision of the system. The magnitude of torque to destabilize an RA from its bony-fixation is unknown. The purpose of this study was to determine the ability of standard RA's to resist applied torque. A digital torque application device was developed to allow for precise torque application to the RA system at four cadavers. Clockwise, gradually increasing rotational force was applied to the RA in 1, 2, or 3 Nm, held for 1 s and released, repeated in 10 cycles. One pin fixation systems with 4.0 Schanz pins were used. A second RA was fixed 20 cm proximal to the tested RA. A navigation system was used to measure the relative positions of both RA's during torque application. The rotational differences at torque application were calculated and statistically evaluated. Results revealed averaged 1.0 degrees rotation [range (r), 1.0-1.1 degrees ] with first cycle of 1 Nm torque, the last cycle averaged 1.0 degrees (r, 1.0-1.1 degrees ) with no significant differences in rotation between any of the cycles (p > 0.5). Torque of 2 Nm resulted in 1.8 degrees rotation (r, 1.5-1.8 degrees ) with no significant increases between first and second cycle (p = 0.56), second and third trials (p = 0.35) while fourth cycle averaged 2.0 degrees , with significant increase (p = 0.011). All subsequent cycles resulted in significant increases. Torque of 3 Nm produced 2.9 degrees of rotation for initial cycle (r,2.5-3.3 degrees ), with significant increases with each cycle (p or =2 Nm may cause loosening of the RA, thus may lose its original position relative to the bone. Surgeons using computer aided surgery systems should be aware of possible

  9. Preferences of referring physicians regarding the role of radiologists as direct communicators of test results.

    Science.gov (United States)

    Erdoğan, Nuri; İmamoğlu, Hakan; Görkem, Süreyya Burcu; Doğan, Serap; Şenol, Serkan; Öztürk, Ahmet

    2017-01-01

    Currently, there is a growing need for patient-centered radiology in which radiologists communicate with patients directly. The aim of this study is to investigate the preferences of referring physicians (RPs) regarding direct communication between radiologists and patients. This study was conducted in a single academic hospital using a survey form. The survey items investigated the preferences of RPs regarding: 1. who should be the communicator of test results when a patient with abnormal findings requests information (the options were the radiologist; another health professional with communication skills training (CST); and the RP with CST); and 2. how the communication activity should be conducted if the radiologist is obliged (or chooses) to communicate with the patient directly (the options were that the disclosure should be limited to the findings in the radiology report; the radiologist should emphasize that the RP is the primary physician; and the communication activity should be conducted in accordance with guidelines established by consensus). The respondents were 101 RPs from various fields of specialty; they were asked to rate the items using a 5-point Likert scale. The effects of age, sex, field of specialty (surgical vs. nonsurgical), and total years of experience as a medical specialist on the ratings were statistically compared. Most RPs preferred that the radiologist transmit the information to the RP without communicating directly with the patient (89.1%). Although 69.3% of the RPs declared that health professionals with CST have priority in communication, 86.1% declared that the RP should be the person who received CST. If the radiologist communicates with patients directly, the RPs favored that 1. the disclosure should be limited to the findings in the radiology report (95%); 2. the communication activity should include an emphasis on the RP as the patient's primary agent (84.1%); and 3. communication should be conducted in accordance with

  10. Acquisition of compounds in Estonian and Russian: Frequency, productivity, transparency and simplicity effect

    Directory of Open Access Journals (Sweden)

    Reili Argus

    2013-04-01

    Full Text Available This article discusses the early phases of acquisition of noun compounds in two typologically different languages – Estonian and Russian. Longitudinal data on three Russian and two Estonian typically-developing monolingual children and their caregivers was analysed and compared in relation to first emergence, the development of different compound types, productivity, frequency, simplicity and transparency of compounds, and also to the impact of morphological wealth in the input on the output. Although the frequency of compounds is somewhat different in the two languages being observed, the first compounds emerge in the speech of Estonian and Russian children almost at the same age and quite early, at the end of the second year of life. In both Estonian and Russian, children first acquire productive pat- terns in both languages, Estonian and Russian, respectively. Factors such as simplicity and frequency are intertwined in the acquisition process. Simple structures occur at the same time as frequent ones but it cannot just be assumed that simplicity is a stronger factor influencing the choice of first noun compounds than frequency. Frequency effects are not straightforward: there are differences in the individual usage of compounds by the caregivers, and the frequency of compounds in child-directed speech does not always seem to be reflected in the speech of the children. DOI: http://dx.doi.org/10.5128/ERYa9.02

  11. On the System of Place Name Signs in Estonian Sign Language

    Directory of Open Access Journals (Sweden)

    Liina Paales

    2011-05-01

    Full Text Available A place name sign is a linguistic-cultural marker that includes both memory and landscape. The author regards toponymic signs in Estonian Sign Language as representations of images held by the Estonian Deaf community: they reflect the geographical place, the period, the relationships of the Deaf community with hearing community, and the common and distinguishing features of the two cultures perceived by community's members. Name signs represent an element of signlore, which includes various types of creative linguistic play. There are stories hidden behind the place name signs that reveal the etymological origin of place name signs and reflect the community's memory. The purpose of this article is twofold. Firstly, it aims to introduce Estonian place name signs as Deaf signlore forms, analyse their structure and specify the main formation methods. Secondly, it interprets place-denoting signs in the light of understanding the foundations of Estonian Sign Language, Estonian Deaf education and education history, the traditions of local Deaf communities, and also of the cultural and local traditions of the dominant hearing communities. Both perspectives - linguistic and folkloristic - are represented in the current article.

  12. On the System of Place Name Signs in Estonian Sign Language

    Directory of Open Access Journals (Sweden)

    Liina Paales

    2010-12-01

    Full Text Available A place name sign is a linguistic-cultural marker that includes both memory and landscape. The author regards toponymic signs in Estonian Sign Language as representations of images held by the Estonian Deaf community: they reflect the geographical place, the period, the relationships of the Deaf community with hearing community, and the common and distinguishing features of the two cultures perceived by community's members. Name signs represent an element of signlore, which includes various types of creative linguistic play. There are stories hidden behind the place name signs that reveal the etymological origin of place name signs and reflect the community's memory. The purpose of this article is twofold. Firstly, it aims to introduce Estonian place name signs as Deaf signlore forms, analyse their structure and specify the main formation methods. Secondly, it interprets place-denoting signs in the light of understanding the foundations of Estonian Sign Language, Estonian Deaf education and education history, the traditions of local Deaf communities, and also of the cultural and local traditions of the dominant hearing communities. Both perspectives - linguistic and folkloristic - are represented in the current article.

  13. Radon in Estonian dwellings - Results from a National Radon Survey

    Energy Technology Data Exchange (ETDEWEB)

    Pahapill, Lia; Rulkov, Anne; Rajamaee, Raivo [Estonian Radiation Protection Centre (Kiirguskeskus), Tallinn (Spain); Aakerblom, Gustav [Swedish Radiation Protection Authority, Stockholm (Sweden)

    2003-10-01

    A countrywide survey of radon concentrations in Estonian dwellings was carried out during the period 1998-2001. The survey formed a part of the cooperation program on radiation protection between the Estonian Radiation Protection (Kiirguskeskus) Centre and the Swedish Radiation Protection Authority (SSI). The survey included measurements in a number of dwellings representative for Estonia in detached houses and multifamily buildings (only dwellings on the bottom floor were included in the survey). Altogether, radon concentrations were measured in 515 dwellings, a number large enough to be statistically significant. All measurements were made with alphatrack film detectors of the same type that SSI uses in Sweden. The measurements were made during a 2-3 month period during the winter half-year. Two detectors were used in each dwelling. In Estonia there are 0.17 million dwellings in detached houses and 0.45 million in multi apartment buildings. Of the 1.26 million inhabitants in Estonia. 0.36 million live in detached houses and 0.90 million in multi apartment buildings. Most of the latter were built during the Soviet occupation. Of the dwellings in multifamily buildings 30 % are assumed to be situated on the first floor. The mean radon concentration in dwellings in detached hoses, according to the survey results, is 103 Bq/m{sup 3}, in dwellings on the bottom floor in multi apartment buildings it is 78 Bq/m{sup 3}. In 1% of the dwellings the radon concentration exceeded 400 Bq/m{sup 3}. The highest radon concentration found in the study was 1040 Bq/m{sup 3}. Based on the assumption that the average radon concentration in the dwellings in multi-apartment buildings that are not situated on the bottom floor is 30 Bq/m{sup 3}, and that these dwellings constitute 70% of all dwellings in multi apartment buildings, the mean radon concentration in dwellings in multi apartment buildings is calculated to be 44 Bq/m{sup 3}. The mean value for all Estonia dwellings is calculated

  14. Frost related dieback in Estonian energy plantations of willows in relation to fertilisation and pathogenic bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Cambours, M.A.; Nejad, P. [Department of Forest Mycology and Pathology, Swedish University of Agricultural Sciences, Box 7026, 750 07 Uppsala (Sweden); Heinsoo, K. [Institute of Zoology and Botany, Estonian Agricultural University, Riia 181, 51014 Tartu (Estonia); Granhall, U. [Department of Microbiology, Swedish University of Agricultural Sciences, Box 7025, 750 07 Uppsala (Sweden)

    2006-03-15

    Two 9-year old Estonian Salix plantations suffering from dieback were studied: one situated on poor mineral soil and divided into fertilised and unfertilised plots (Saare plantation) and another growing on a well-decomposed and nitrogen-rich organic soil, without fertiliser application (Kambja plantation). Bacteria from internal tissues of visually damaged shoots from seven clones were isolated in spring and autumn. The strains were subsequently biochemically characterised and tested for ice nucleation activity and pathogenicity on Salix. Some strains were also analysed with 16S rRNA. High numbers of culturable bacteria were found, belonging mainly to Erwinia, Sphingomonas, Pseudomonas and Xanthomonas spp. Fertilised plots were significantly more colonised by bacteria than unfertilised plots and also more extensively damaged, showing a lower density of living plants after 7 years of culture. More ice nucleation active (INA) strains were found in Saare fertilised plots and at Kambja than in Saare unfertilised plots. Likewise, most pathogenic strains were isolated from Saare fertilised plots and from Kambja. For some of the willow clones studied, dieback appeared to be related to both clonal frost sensitivity and abundance of INA and pathogenic bacteria. The plantations probably suffered from the presence of high amounts of pathogens and from frost related injuries aggravated by INA bacteria. Most probably the fertilisation at Saare and the nitrogen-rich soil at Kambja created a favourable environment for bacterial development and led to high dieback levels after the first harvest. (author)

  15. Reference test methods for total water in lint cotton by Karl Fischer Titration and low temperature distillation

    Science.gov (United States)

    In a study of comparability of total water contents (%) of conditioned cottons by Karl Fischer Titration (KFT) and Low Temperature Distillation (LTD) reference methods, we demonstrated a match of averaged results based on a large number of replications and weighing the test specimens at the same tim...

  16. Estrogen and progesterone receptor testing in breast carcinoma: concordance of results between local and reference laboratories in Brazil

    Directory of Open Access Journals (Sweden)

    Sheila Cristina Lordelo Wludarski

    Full Text Available CONTEXT AND OBJECTIVE: Breast cancer accounts for approximately one quarter of all cancers in females. Estrogen and progesterone receptor testing has become an essential part of the clinical evaluation of breast carcinoma patients, and accurate results are critical in identifying patients who may benefit from hormone therapy. The present study had the aim of investigating the concordance of the results from hormone receptor tests between a reference laboratory and local (or community laboratories in Brazil. DESIGN AND SETTING: Retrospective study at a reference pathology laboratory. METHODS: The concordance in the results from hormone receptor tests between a reference laboratory and 146 local laboratories in Brazil was compared in relation to 500 invasive breast carcinoma cases, using immunohistochemistry. RESULTS: There was concordance in 89.4% (447/500 cases and 85.0% (425/500 cases of the results from estrogen (κ = 0.744, P < 0.001 and progesterone (κ = 0.688, P < 0.001 receptor tests, respectively, between local and reference laboratories. This was similar to findings in other countries. The false negative rates from estrogen and progesterone receptor tests in local laboratories were 8.7% and 14.4%, respectively. The false positive rates from estrogen and progesterone receptor tests in local laboratories were 15.5% and 16.0%, respectively. CONCLUSION: Technical and result interpretation issues may explain most of the discordances in hormone receptor testing in local laboratories. Validation of estrogen and progesterone receptor tests at local laboratories, with rigorous quality control measures, is strongly recommended in order to avoid erroneous treatment of breast cancer patients.

  17. Design and test of an artificial reference cow to simulate methane release through exhalation

    NARCIS (Netherlands)

    Wu, Liansun; Groot Koerkamp, P.W.G.; Ogink, N.W.M.

    2015-01-01

    To mitigate methane emission from dairy cows, a technique is needed to evaluate individual methane emission from a large number of cows under practical conditions in barns. For developing such a measurement technique, a known reference source that can simulate cow exhalation of methane would be a

  18. The Reciprocal Internal/External Frame of Reference Model Using Grades and Test Scores

    Science.gov (United States)

    Möller, Jens; Zimmermann, Friederike; Köller, Olaf

    2014-01-01

    Background: The reciprocal I/E model (RI/EM) combines the internal/external frame of reference model (I/EM) with the reciprocal effects model (REM). The RI/EM extends the I/EM longitudinally and the REM across domains. The model predicts that, within domains, mathematics and verbal achievement (VACH) and academic self-concept have positive effects…

  19. Genetics Home Reference: sudden infant death with dysgenesis of the testes syndrome

    Science.gov (United States)

    ... SIDDT Sudden infant death with dysgenesis of the testes syndrome Printable PDF Open All Close All Enable ... Description Sudden infant death with dysgenesis of the testes syndrome ( SIDDT ) is a rare condition that is ...

  20. The Effect of Scale Referent on Tests of Mean Structure Parameters

    Science.gov (United States)

    Kang, Yoonjeong; Hancock, Gregory R.

    2017-01-01

    Structured means analysis is a very useful approach for testing hypotheses about population means on latent constructs. In such models, a z test is most commonly used for testing the statistical significance of the relevant parameter estimates or of the differences between parameter estimates, where a z value is computed based on the asymptotic…

  1. Health hazards associated with the use of di-(2-ethylhexyl) phthalate (commonly referred to as DOP) in HEPA filter test

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-01-01

    Di-(2-ethylhexyl) phthalate (DEHP), commonly referred to as di-octyl phthalate, is an important production chemical in the US. In addition to its major use as an additive in plastics, DEHP is widely used to evaluate the effectiveness of high efficiency particulate air (HEPA) filters. Historically, DEHP was also used in quantitative fit testing for respirators. Evaluations of this compound a decade ago showed that it can induce hepatocellular carcinomas in laboratory animals. Although most Department of Energy (DOE) facilities have since discontinued using DEHP in respirator fit testing, DEHP continues to be used for evaluating HEPA filters. This report summarizes available information on the toxicity, mutagenicity, carcinogenicity, and other hazards and problems posed by DEHP, specifically with reference to HEPA filter testing. Information on work practice improvements as well as the availability and suitability of DEHP substitutes are also presented. This material should assist the DOE in the safe use of this material.

  2. The Woman as Wolf (AT 409: Some Interpretations of a Very Estonian Folk Tale

    Directory of Open Access Journals (Sweden)

    Merili Metsvahi

    2013-12-01

    Full Text Available The article analyses tale type The Woman as Wolf, which is one of the most popular folk tales in the Estonian Folklore Archives and is represented there both in the form of a fairy tale and in the form of a legend. The vast majority of the versions of The Woman as Wolf were written down in the first part of the 20th century within Estonia and where recorded from Estonians. The article introduces the content of the tale, the origin of the first records from the early 19th century, and the dissemination area of the tale, which remains outside Western Europe: apart from the Estonian versions there are Sami, Karelian, Vepsian, Livonian, Latvian, Lithuanian, Russian, Ukrainian and Belarusian versions. While in almost all the Estonian versions the main protagonist is transformed into a wolf, in most of the versions written down in other areas and ethnic groups, another animal or bird replaces the wolf. The author is of the opinion that the Finnic area is central to the distribution of the folk tale The Woman as Wolf. The animal the woman is transformed into in the plot would not have been a wolf in earlier times. The article provides an explanation why the wolf is predominant in Estonian written sources. For that purpose the ways in which the wolf and werewolf were perceived in earlier Estonian folk belief are introduced. At the end of the article interpretation of the folk tale is provided. The author states that the plot and some of the motifs found in this folk tale reflect the difficulties women had in submitting to the norms and values of patriarchal order within their society.

  3. MODELLING DICLOFENAC AND IBUPROFEN RESIDUES IN MAJOR ESTONIAN SEASIDE CITIES

    Directory of Open Access Journals (Sweden)

    Erki Lember

    2016-06-01

    Full Text Available A theoretical model was developed to model the fate of two common pharmaceutical residues: diclofenac and ibuprofen in eight Estonian seaside cities that discharge their wastewaters directly into the Baltic Sea. The consumption rates of the active ingredients of diclofenac and ibuprofen from 2006-2014 were analysed. A decrease of 19.9% for diclofenac consumption and an increase of 14.1% for ibuprofen were found. The fate of diclofenac and ibuprofen were modelled by considering the human metabolism removal rate for pharmaceuticals, the removal rate of diclofenac and ibuprofen in activated sludge wastewater treatment plants (WWTP and annual flow rates. An average decrease from 1 to 0.8 µg/l (decrease of 20% for diclofenac and an increase from 11.4 to 13.4 µg/l (increase of 14.9% for ibuprofen for the concentration in the effluents of the WWTP were modelled. The model gives us a good overview about the theoretical concentrations of pharmaceutical residues in the environment and is helpful for evaluating environmental impacts.

  4. Static renewal tests using Anodonta imbecillis (freshwater mussels). Anodonta imbecillis copper sulfate reference toxicant/food test, Clinch River-Environmental Restoration Program (CR-ERP)

    Energy Technology Data Exchange (ETDEWEB)

    Simbeck, D.J.

    1993-12-31

    Reference toxicant testing using juvenile freshwater mussels was conducted as part of the CR-ERP biomonitoring study of Clinch River sediments to assess the sensitivity of test organisms and the overall performance of the test. Tests were conducted using moderately hard synthetic water spiked with known concentrations of copper as copper sulfate. Two different foods, phytoplankton and YCT-Selenastrum (YCT-S), were tested in side by side tests to compare food quality. Toxicity testing of copper sulfate reference toxicant was conducted from July 6--15, 1993. The organisms used for testing were juvenile fresh-water mussels (Anodonta imbecillis). Although significant reduction in growth, compared to the phytoplankton control, was seen in all treatments, including the YCT-S Control, the consequence of this observation has not been established. Ninety-day testing of juvenile mussels exhibited large variations in growth within treatment and replicate groups. Attachments to this report include: Toxicity test bench sheets and statistical analyses; and Copper analysis request and results.

  5. Eesti pagulaskirjanduse keskus ja perifeeria / The centre and periphery of Estonian exile literature

    Directory of Open Access Journals (Sweden)

    Sirje Olesk

    2016-09-01

    Full Text Available This article focuses on how and why the centre and periphery of Estonian exile literature were formed. The centre developed in Sweden with the founding of the Estonian Writers’ Union Abroad in 1945 in Stockholm, and the Estonian Writers’ Cooperative in 1951 in Lund. Exile literature with the most enduring artistic merit was published in this Lund-Stockholm axis. The Writers’ Cooperative was a well-managed publishing house that took into account readers’ requests. Almost all significant writers in exile issued their works through the Cooperative. Writers whose works were rejected by the Cooperative formed the pheriphery of exile literature. The boundary between the two was not rigid, with movement from one grouping to the other, although the centre remained united. In 1957, writers of the younger generation on the periphery founded the literary magazine Mana, which devoted a great deal of space to literature published in the homeland, unlike the centre. This relationship with homeland literature differentiated the centre from the periphery. The writers of the centre did not visit the occupied homeland or publicly recognize the works of writers from Soviet Estonia. For them, it was vital to maintain control over the purity and viability of exile literature. Exile publishing flourished in the 1940s and 1950s, as homesickness and limited fluency in local languages increased interest in books written in Estonian. Later, this interest inevitably and steadily decreased. The younger generation of exiles often read in the language of the country where they had settled. It was possible to send only a very few books to the homeland. Leading writers-in-exile Bernard Kangro, Karl Ristikivi, Valev Uibopuu, Kalju Lepik, Ilmar Talve and others did their utmost to publish and distribute their works because they regarded literature as the foundation of national identity. It was necessary to protect this identity, and any competition with homeland

  6. Estonian Perceptions of Security: Not Only About Russia and the Refugees

    Directory of Open Access Journals (Sweden)

    Veebel Viljar

    2016-12-01

    Full Text Available The current study focuses on the Estonian perceptions of security and on the defence situation both globally and locally. The dynamic results of the public opinion surveys on security risks conducted in Estonia over the last 10 years (2006-2016 will be presented. In addition, to understand whether some of the security risks could be over- or underestimated in Estonia, these results will be compared with the views expressed recently by the World Economic Forum, particularly the Global Risks Report 2016. Also, the arguments why some topics have played or are currently playing key role in the Estonian security perception will be presented and discussed.

  7. Allergic contact dermatitis in Danish children referred for patch testing - a nationwide multicentre study

    DEFF Research Database (Denmark)

    Simonsen, Anne Birgitte; Deleuran, Mette; Mortz, Charlotte Gotthard

    2014-01-01

    -17 years, 25.1% had one or more positive patch test reactions. The associated relevance was 66.4%. The most common sensitizers were metals, fragrances, and hair dyes. The frequency of positive patch test reactions and allergic contact dermatitis was significantly higher among girls. CONCLUSIONS: Allergic...... during 2003-2011, to examine the frequency and relevance of positive patch test reactions, and to assess the most common allergens. METHODS: A retrospective analysis of the patch test data from the Danish National Database of Contact Allergy was performed. RESULTS: Of 2594 children and adolescents aged 1...

  8. Development and characterization of reference materials for MTHFR, SERPINA1, RET, BRCA1, and BRCA2 genetic testing.

    Science.gov (United States)

    Barker, Shannon D; Bale, Sherri; Booker, Jessica; Buller, Arlene; Das, Soma; Friedman, Kenneth; Godwin, Andrew K; Grody, Wayne W; Highsmith, Edward; Kant, Jeffery A; Lyon, Elaine; Mao, Rong; Monaghan, Kristin G; Payne, Deborah A; Pratt, Victoria M; Schrijver, Iris; Shrimpton, Antony E; Spector, Elaine; Telatar, Milhan; Toji, Lorraine; Weck, Karen; Zehnbauer, Barbara; Kalman, Lisa V

    2009-11-01

    Well-characterized reference materials (RMs) are integral in maintaining clinical laboratory quality assurance for genetic testing. These RMs can be used for quality control, monitoring of test performance, test validation, and proficiency testing of DNA-based genetic tests. To address the need for such materials, the Centers for Disease Control and Prevention established the Genetic Testing Reference Material Coordination Program (GeT-RM), which works with the genetics community to improve public availability of characterized RMs for genetic testing. To date, the GeT-RM program has coordinated the characterization of publicly available genomic DNA RMs for a number of disorders, including cystic fibrosis, Huntington disease, fragile X, and several genetic conditions with relatively high prevalence in the Ashkenazi Jewish population. Genotypic information about a number of other cell lines has been collected and is also available. The present study includes the development and commutability/genotype characterization of 10 DNA samples for clinically relevant mutations or sequence variants in the following genes: MTHFR; SERPINA1; RET; BRCA1; and BRCA2. DNA samples were analyzed by 19 clinical genetic laboratories using a variety of assays and technology platforms. Concordance was 100% for all samples, with no differences observed between laboratories using different methods. All DNA samples are available from Coriell Cell Repositories and characterization information can be found on the GeT-RM website.

  9. Optimizing cross-sectional prediction of social functioning in youth referred for neuropsychological testing.

    Directory of Open Access Journals (Sweden)

    Matthew D Lerner

    Full Text Available The current study aimed to establish a fine-grained, efficient characterization of the concurrent neuropsychological contributions to social functioning in neuropsychologically-referred youth. A secondary aim was to demonstrate a useful statistic approach for such investigations (Partial Least Squares Regression; PLSR, which is underutilized in this field. Forty-five participants (70 - 164 months; Mage = 110.89; 34 male were recruited from a large neuropsychological assessment clinic. Participants completed subtests from the NEPSY-II focusing on neuropsychological constructs that have been linked to social functioning (affect decoding, social memory, motor skills, visuomotor skills, response inhibition, attention and set-shifting, and verbal comprehension. Mothers completed the BASC-2, from which Atypicality and Social Skills scales were analyzed. PLSR revealed that difficulty with social memory, sensorimotor integration, and the ability to attend to and accurately discriminate auditory stimuli combine to best predict atypical or "odd" behavior. In terms of social skills, two factors emerged. The first factor indicated that, counterintuitively, greater emotional perception, visuospatial perception, ability to attend to and accurately discriminate auditory stimuli, and understand instructions was related to poorer social skills. The second factor indicated that a pattern of better facial memory, and sensorimotor ability (execution & integration characterized a distinct profile of greater social ability. PLSR results were compared to traditional OLS and Backwards Stepwise regression approaches to demonstrate utility. Results also suggested that these findings were consistent across age, gender, and diagnostic group, indicating common neuropsychological substrates of social functioning in this sample of referred youth. Overall, this study provides the first characterization of optimized combinations of neuropsychological variables in predicting

  10. Experimental Wave Tank Test for Reference Model 3 Floating-Point Absorber Wave Energy Converter Project

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Y. H. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lawson, M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Li, Y. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Previsic, M. [Re Vision Consulting, Sacramento, CA (United States); Epler, J. [Re Vision Consulting, Sacramento, CA (United States); Lou, J. [Oregon State Univ., Corvallis, OR (United States)

    2015-01-01

    The U.S. Department of Energy established a reference model project to benchmark a set of marine and hydrokinetic technologies including current (tidal, open-ocean, and river) turbines and wave energy converters. The objectives of the project were to first evaluate the status of these technologies and their readiness for commercial applications. Second, to evaluate the potential cost of energy and identify cost-reduction pathways and areas where additional research could be best applied to accelerate technology development to market readiness.

  11. On Further Examination of "On Further Examination." Quick Reference: Testing/SAT.

    Science.gov (United States)

    National Education Association, Washington, DC.

    Discussions of any test must focus on reliability, content validity, and interpretation of results. In this critique of On Further Examination--the report of the Advisory Panel on the Scholastic Aptitude Test (SAT) Score Decline--the National Education Association (NEA) finds no fault with the reliability of the SAT. Its content validity, however,…

  12. Flight Test of Composite Model Reference Adaptive Control (CMRAC) Augmentation Using NASA AirSTAR Infrastructure

    Science.gov (United States)

    Gregory, Irene M.; Gadient, ROss; Lavretsky, Eugene

    2011-01-01

    This paper presents flight test results of a robust linear baseline controller with and without composite adaptive control augmentation. The flight testing was conducted using the NASA Generic Transport Model as part of the Airborne Subscale Transport Aircraft Research system at NASA Langley Research Center.

  13. Prevalence of self-reported food allergy and IgE antibodies to food allergens in Swedish and Estonian schoolchildren.

    Science.gov (United States)

    Sandin, A; Annus, T; Björkstén, B; Nilsson, L; Riikjärv, M-A; van Hage-Hamsten, M; Bråbäck, L

    2005-03-01

    To compare the prevalence of self-reported food allergy and IgE antibodies to food allergens in wheezing and non-wheezing Estonian and Swedish schoolchildren, in the light of the disparities in the standard of living, food consumption and prevalence of respiratory allergies that still exist between Estonia and the Scandinavian countries. As a part of the ISAAC Phase II study, children from a random sample of schools in Tallinn in Estonia and Linköping and Ostersund in Sweden participated in skin prick tests to inhalant allergens and the parents replied to questionnaires. IgE antibodies against a panel of food allergens (egg white, milk, soy bean, fish, wheat and peanut) were taken from children with questionnaire-reported wheezing and a random sample of nonwheezing children. Children aged 10-11 y. The prevalence of self-reported food allergy was similar in Estonia and Sweden and about twice as high in wheezing children than in nonwheezing children. In Estonia, however, 3% of the children with perceived food allergy reported reactions from at least four different foods, as compared to 31% in Sweden. The prevalence of sensitisation to food allergens was similar in wheezing and nonwheezing children in Estonia (8%) while, in Swedish children, IgE antibodies to food allergens were more likely among wheezing children (Linköping 38 vs 11%, crude OR 5.1, 95% CI 2.2-11.6, and Ostersund 24 vs 7%, crude OR 4.1, 95% CI 1.9-8.5). Our study suggests that IgE-mediated food reactions were less likely in Estonian schoolchildren. Moreover, the perception of food allergy and thereby the meaning of self-reported food allergy appears to be different in the two countries.

  14. Ten years experience of isotopic breath test with special reference to Helicobacter pylori detection

    Energy Technology Data Exchange (ETDEWEB)

    Verhas, M.; Tricht, L.Van; Verschaeren, A.; Delmotte, E.; Martin, P

    1997-12-31

    The use of the carbon 14 urea breath test by comparison with culture for campylobacter of gastric endoscopic biopsies is studied in 91 patients. They were divided into 2 groups. The first group consisted of 53 patients examined by gastric endoscopy and carbon 14 urea breath test. In this population, gastric biopsies were taken at different regions of the stomach and duodenum. The breath test was performed within 3 hours after endoscopy. The second group consisted of 38 asymptomatic patients whom 23 were parent of children with campylobacter positive gastritis. For the whole population, neither antibiotic therapy nor bismuth medication was administrated within the 15 days before the realization of the test. Results were expressed in % of injected dose/mmole of CO{sub 2} after correction of endogenous production of CO{sub 2}. In conclusion, carbon 14 urea breath test is a reliable noninvasive test for detection and follow-up of gastritis caused by a widespread microorganism. Also, the precision of both tests, {sup 14} C-UBT and {sup 13} C-UBT, are compared simultaneously in 84 adults patients. The results were expressed as % of administered dose expired in 30 minutes. A better precision is observed with the {sup 13} C-UBT

  15. Equivalence testing using existing reference data: An example with genetically modified and conventional crops in animal feeding studies.

    Science.gov (United States)

    van der Voet, Hilko; Goedhart, Paul W; Schmidt, Kerstin

    2017-11-01

    An equivalence testing method is described to assess the safety of regulated products using relevant data obtained in historical studies with assumedly safe reference products. The method is illustrated using data from a series of animal feeding studies with genetically modified and reference maize varieties. Several criteria for quantifying equivalence are discussed, and study-corrected distribution-wise equivalence is selected as being appropriate for the example case study. An equivalence test is proposed based on a high probability of declaring equivalence in a simplified situation, where there is no between-group variation, where the historical and current studies have the same residual variance, and where the current study is assumed to have a sample size as set by a regulator. The method makes use of generalized fiducial inference methods to integrate uncertainties from both the historical and the current data. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Reference materials and representative test materials to develop nanoparticle characterization methods: the NanoChOp project case

    Directory of Open Access Journals (Sweden)

    Gert eRoebben

    2015-10-01

    Full Text Available This paper describes the production and characteristics of the nanoparticle test materials prepared for common use in the collaborative research project NanoChOp (Chemical and optical characterisation of nanomaterials in biological systems, in casu suspensions of silica nanoparticles and CdSe/CdS/ZnS quantum dots. This paper is the first to illustrate how to assess whether nanoparticle test materials meet the requirements of a 'reference material' (ISO Guide 30:2015 or rather those of the recently defined category of 'representative test material' (ISO TS 16195:2013. The NanoChOp test materials were investigated with small-angle X-ray scattering (SAXS, dynamic light scattering (DLS and centrifugal liquid sedimentation (CLS to establish whether they complied with the required monomodal particle size distribution. The presence of impurities, aggregates, agglomerates and viable microorganisms in the suspensions was investigated with DLS, CLS, optical and electron microscopy and via plating on nutrient agar. Suitability of surface functionalization was investigated with attenuated total reflection Fourier transform infrared spectrometry (ATR-FTIR and via the capacity of the nanoparticles to be fluorescently labeled or to bind antibodies. Between-unit homogeneity and stability were investigated in terms of particle size and zeta potential. This paper shows that only based on the outcome of a detailed characterization process one can raise the status of a test material to representative test material or reference material, and how this status depends on its intended use.

  17. Evaluation of Methacholine Challenge Test Results in Chronic Cough Patients Referring to Clinic of Pulmonary Disease

    Directory of Open Access Journals (Sweden)

    Derakhshan Deilami Gholamreza

    2009-10-01

    Full Text Available Chronic cough is a common problem in patients visiting physicians and its prevalence in different populations range from 3 to 40%. Postnasal drip, asthma and gastroesophageal reflux are the known cause of chronic cough. Although diagnosis of asthma is usually made by clinical signs and spirometeric results, methacholine challenge test is a good diagnostic test in patients who show normal physical examination and spirometeric results. In this study, the results of methacholine challenge test in chronic cough patients are investigated. This is a cross sectional study performed on patients suffering from chronic cough (over 8 weeks, who went to Pulmonary Disease Clinic of Imam Khomeini Hospital in 2006. Postnasal drip, gastroesophageal reflux was evaluated and ruled out in all patients. Then they were tested by methacholine inhalation using low to high doses of methacholine. The results of test was defined as 20% fall in FEV1 and its relationship with age, sex, history of allergic disease, family history of asthma and smoking status was investigated. 81 patients (36 female and 45 male entered this study who had mean age of 32.5 ± 13.06 years. 81.5% of patients had never smoked or closed contact with smokers, 6.2% were passive smokers, 8.6% were smokers and 3.7% had quit smoking. 37% had suffered from chronic cough less than 6 months, 11% for 6-11 months and 52% for more than 12 months. In 26% of patients, family history of asthma was present and 34.5% had a history of one type of allergy. In 29.5% the results of methacholine challenge test was positive, among them 45.8% showed an intense response and 54.2% a moderate response. The test results and its intensity had no statistically significant relationship with age, sex, smoking status, the duration of cough and family history of asthma, but the relationship between methacholine challenge test and the history of allergic disease was significant. Methacholine challenge test can be used as a

  18. Test atmospheres of diisocyanates with special reference to controlled exposure of humans.

    Science.gov (United States)

    Brorson, T; Skarping, G; Renman, L; Sangö, C

    1989-01-01

    An all glass apparatus for the generation of air concentrations of 2,4-toluene diisocyanate (2,4-TDI), 2,6-toluene diisocyanate (2,6-TDI) and 1,6-hexamethylene diisocyanate (HDI) was developed. The generation principle was based on gas-phase permeation with permeation membranes of silicon rubber. In an 8 m3 stainless steel test chamber, low and steady TDI-and HDI atmospheres (1-100 micrograms/m3) could be maintained. The diisocyanate concentrations were determined by an HPLC method, using the 9-(N-methylaminomethyl)-anthracene reagent utilizing UV detection. The sum of diisocyanates and their related amines were determined by sampling in 0.4 M hydrochloric acid solution, and analysis by capillary gas chromatography with thermionic specific detection. Related amines were determined by sampling in ethanol - 0.2% KOH and analysis on GC-TSD. A continuous band-tape monitor was used for the determination of diisocyanates. Losses of diisocyanates in the test chamber were evaluated by measuring the TDI and HDI concentrations at the inlet respectively the outlet of the test chamber. At the outlet of the test chamber, ca 25% of the TDI respectively HDI concentrations were recovered. With a male subject in the test chamber ca 15% of the HDI concentration was recovered. The air flow through the test chamber was ca 10 m3/h. The changes in isomeric composition of airborne TDI, at stopped flow conditions, showed that the decay of the 2,4-isomer was faster than of the 2,6-isomer. No trace of the related amine toluene diamine (TDA) was detected in the test chamber, at TDI concentrations ranging from 20 to 50 micrograms/m3. Sampling losses due to sampling connections were evaluated.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. The problems and development potential of revenue autonomy in Estonian municipalities. Kohalike omavalitsuste tuluautonoomia probleemid ja arenguvõimalused Eestis

    Directory of Open Access Journals (Sweden)

    Janno Reiljan

    2013-01-01

    Full Text Available In a regionally heterogeneous country like Estonia, it is a difficult task to create a local government revenue structure that guarantees even supply of public services across the entire country and, at the same time, revenue autonomy for the municipalities. In the theoretical part of the current article the suitability of different sources of own revenues are analysed in the context of Estonian municipalities. The empirical part of the article compares the financing principles of Estonian municipalities with other EU countries. Finally, the proportions of different own sources of revenues in the budgets of Estonian local governments are examined and suggestions are made for changing the current system

  20. The possibility of compensation for damages in cases of wrongful conception, wrongful birth and wrongful life. An Estonian perspective.

    Science.gov (United States)

    Sõritsa, Dina; Lahe, Janno

    2014-04-01

    While case law in cases of wrongful conception, wrongful birth and wrongful life is completely missing in Estonia, this article is aimed at providing possible solutions under Estonian law to some of the legally complex problems that these cases contain. Through the analysis of Estonian, German and U.S. legal literature and case law, the article is mainly focused on proposing some solutions to the legal problems concerning compensable damage, but also explains the Estonian legal framework of the contractual and delictual basis for compensation for the damages. The application of several grounds for the possibility of limiting the compensation in the afore-mentioned cases are analysed.

  1. Modelling the heat dynamics of a monitored Test Reference Environment for Building Integrated Photovoltaic systems using stochastic differential equations

    DEFF Research Database (Denmark)

    Lodi, C.; Bacher, Peder; Cipriano, J.

    2012-01-01

    prediction of the most influential variables. The experimental data originates from tests carried out with an air-based BIPV system installed in a Test Reference Environment. BIPV systems represent an interesting application for achieving the requirements of the EU EPBD Directive. Indeed, these systems could...... reduce the ventilation thermal losses of the building by pre-heating the fresh air. Furthermore, by decreasing PV module temperature, the ventilation air heat extraction can simultaneously increase electrical and thermal energy production of the building. A correct prediction of the PV module temperature...

  2. Swiss population-based reference data for six symptom validity tests

    Directory of Open Access Journals (Sweden)

    Peter Giger

    2013-01-01

    Full Text Available Los resultados encontrados en la evaluación de la validez de los síntomas (SVT deberían ser inmunes a las variables sociodemográficas. Así, los sujetos sanos y cooperadores deberían superar los tests de SVT. El ob- jetivo de este estudio es obtener datos de referencia de una serie de pruebas utilizadas en la evaluación de la validez de los síntomas, en una muestra representativa de 100 ciudadanos suizos, germano-hablantes, de entre 18 y 60 años: Medical Symptom Validity Test, Structured Inventory of Malingered Symptomatology, Amsterdam Short-Term Memory Test, Emotional Numbing Test, Reliable Digit Span y Maximum Span Forward. Los análisis de regresión múltiple reflejaron que las variables edad e inteligencia verbal afectaron a los resultados de varias de las pruebas, mientras que no fue así para las variables sexo y nivel educativo. La tasa de resultados positivos osciló entre el 1% (Emotional Numbing Test, Structured Inventory of Malin- gered Symptomatology y el 4% (Maximum Span Forward. Una cuestión relevante que se desprende de este estudio es si dichos resultados positivos en las muestras de referencia

  3. Computation of Estonian CORS data using Bernese 5.2 and Gipsy 6.4 softwares

    Science.gov (United States)

    Kollo, Karin; Kall, Tarmo; Liibusk, Aive

    2017-04-01

    GNSS permanent station network in Estonia (ESTREF) was established already in 2007. In 2014-15 extensive reconstruction of ESTREF was carried out, including the establishment of 18 new stations, change of the hardware in CORS stations as well as establishing GNSS-RTK service for the whole Estonia. For GNSS-RTK service one needs precise coordinates in well-defined reference frame, i.e., ETRS89. For long time stability of stations and time-series analysis the re-processing of Estonian CORS data is ongoing. We re-process data from 2007 until 2015 with program Bernese GNSS 5.2 (Dach, 2015). For the set of ESTREF stations established in 2007, we perform as well computations with GIPSY 6.4 software (Ries et al., 2015). In the computations daily GPS-only solution was used. For precise orbits, final products from CODE (CODE analysis centre at the Astronomical Institute of the University of Bern) and JPL (Jet Propulsion Laboratory) for Bernese and GIPSY solutions were used, respectively. The cut-off angle was set to 10 degrees in order to avoid near-field multipath influence. In GIPSY, precise point positioning method with fixing ambiguities was used. Bernese calculations were performed based on double difference processing. Antenna phase centers were modelled based on igs08.atx and epnc_08.atx files. Vienna mapping function was used for mapping tropospheric delays. For the GIPSY solution, the higher order ionospheric term was modelled based on IRI-2012b model. For the Bernese solution higher order ionospheric term was neglected. FES2004 ocean tide loading model was used for the both computation strategies. As a result, two solutions using different scientific GNSS computation programs were obtained. The results from Bernese and GIPSY solutions were compared, using station repeatability values, RMS and coordinate differences. KEYWORDS: GNSS reference station network, Bernese GNSS 5.2, Gipsy 6.4, Estonia. References: Dach, R., S. Lutz, P. Walser, P. Fridez (Eds); 2015

  4. Obstructive sleep apnea syndrome (OSAS): Pathophysiology in Estonians.

    Science.gov (United States)

    Veldi, Marlit; Ani, Raivo; Vaher, Heisl; Eller, Triin; Hion, Tuuliki; Aluoja, Anu; Vasar, Veiko

    2010-06-01

    The aim of the study was to clarify the roles of age, obesity, smoking, alcohol, pathoanatomy and -physiology in Estonian's OSAS. For this 164 randomly chosen such patients were selected in different regions of Estonia. They underwent naso-oropharyngeal examination, physical examination of craniofacial abnormalities, and polysomnography. They also completed a self-reported questionnaire about smoking, alcohol use, excessive daytime sleepiness, hypertension, cardiac disorders, headaches, concentration disorders, and recurrent upper-airway diseases. The patients (129 men; 35 women) aged between 19 and 75 years (mean 47+/-12), BMI between 21 and 49 (mean 30.5+/-5.15), AHI between 5 and 105 (33+/-22). The results showed that there was a high percentage of naso-oropharyngeal disorders, such as: recurrent upper-airway diseases (54.2%), nasal breathing disorders (63.5%), and hypertrophy of tonsils (57%). There was also a high percentage of general characteristics, such as alcohol use (64%), excessive daytime sleepiness (85.5%), overweight (63%), and hypertension (51.2%). The regression summary for the dependent variable AHI if p-level=0.0042 (R=0.63347013) included age, BMI, hypertension, cardiac disorders, headaches, nasal obstruction, hypertrophy of pharyngeal muscles, tongue level, submental fat and slow-wave sleep (S3+S4%). In conclusion recurrent upper-airway diseases, nasal obstruction, and hypertrophy of tonsils in combination with smoking and alcohol caused the changes in the pharyngeal and lingual muscles. The latter gives rise to such sleep apnea-related problems as heart complaints, hypertension, headache and shortage of slow-wave sleep (SWS). Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  5. Estonian Cell peab suu kasumist puhtaks pühkima / Kaisa Tahlfeld, Katre Pilvinski

    Index Scriptorium Estoniae

    Tahlfeld, Kaisa

    2008-01-01

    Estonian Cell saatis valitsusele pöördumise, milles palutakse teha parandusi elektrienergiaga seonduvates seadustes, mis aitaksid ettevõtet energia hinnatõusu ajal. Elektri hinnatõusu tõttu on muutunud küsitavaks ka Nitroferti tehase edasine eksisteerimine

  6. The Woman as Wolf (AT 409): Some Interpretations of a Very Estonian Folk Tale

    National Research Council Canada - National Science Library

    Merili Metsvahi

    2013-01-01

    The article analyses tale type The Woman as Wolf, which is one of the most popular folk tales in the Estonian Folklore Archives and is represented there both in the form of a fairy tale and in the form of a legend...

  7. Alberta's Estonians 1899 - Present TLÜ Akadeemilises Raamatukogus / Sander Jürisson

    Index Scriptorium Estoniae

    Jürisson, Sander

    2014-01-01

    Tallinna Ülikooli Akadeemilises Raamatukogus on üleval näitus "Alberta's Estonians 1899 - Present", mis annab ülevaate Kanada Alberta provintsi eestlaste loost. Näitus valmis Alberta Eesti Kultuuripärandi Seltsi koostöös Alberta Provintsi Arhiivi Kultuuripärandi Osakonnaga Edmontonis

  8. A Cross-Cultural Study of Collectivism: A Comparison of American, Estonian, and Russian Students.

    Science.gov (United States)

    Realo, Anu; Allik, Juri

    1999-01-01

    Investigates the theory that collectivism consists of at least three subtypes focused on the relations with family, peers, and society using a cross-cultural sample from the United States, Estonia, and Russia. Finds that the Estonian sample was the least collectivistic within the three subtypes and the Russian samples were the most collectivistic.…

  9. Consumer Socialisation and Value Orientations among Estonian and Chinese Young People

    Science.gov (United States)

    Waerdahl, Randi; Kalmus, Veronika; Keller, Margit

    2011-01-01

    This paper asks if Estonian and Chinese tweens' access to pocket money influences their brand valuation, as well as value orientations in the context of perceived peer popularity and personal well-being. Surveys conducted in autumns 2006 (China n = 188) and 2007 (Estonia n = 111) show an inherent cultural resistance among tweens in both countries…

  10. Estonian Science and Non-Science Students' Attitudes towards Mathematics at University Level

    Science.gov (United States)

    Kaldo, Indrek; Reiska, Priit

    2012-01-01

    This article investigates the attitudes and beliefs towards studying mathematics by university level students. A total of 970 randomly chosen, first year, Estonian bachelor students participated in the study (of which 498 were science students). Data were collected using a Likert-type scale questionnaire and analysed with a respect to field of…

  11. The 2011 Estonian High School Language Reform in the Context of Critical Language Policy and Planning

    Science.gov (United States)

    Skerrett, Delaney Michael

    2014-01-01

    This paper seeks to situate Estonian language use and policy within the emerging field of critical language policy and planning (CLPP) by investigating the discourses that frame linguistic behaviour. This done by way of an analysis of a series of interviews carried out with key actors in language policy in Estonia. The discourses framing language…

  12. Trends in tobacco use among Estonian and Russian youth in Tallinn.

    Science.gov (United States)

    Nurk, E; Mittelmark, M B; Suurorg, L; Tur, I; Luiga, E

    1999-12-01

    Smoking behaviour and exposure to environmental tobacco smoke (ETS) were examined in three cross-sectional surveys from 1991/92, 1993/94, and 1995/96. The study population comprised 3,185 Estonian and Russian adolescents from 17 schools in Tallinn, Estonia. Prevalence of ever-smoking girls increased by 13 percentage points versus 2% among boys during the study period. Mean ages of the first experimentation with tobacco and exposure to ETS did not change significantly. Regular smoking increased significantly from 1991/92 to 1995/96. Detailed analyses for the 1995/96 survey showed that among ethnic Estonians, compared with ethnic Russians, the prevalence of ever-smokers and regular smoking were higher, mean age for the first experimentation was younger, and on average, Estonians smoked more cigarettes per week. The smoking trend among adolescents in Estonia is worsening; especially among Estonian youth. This study identifies a compelling need for national and community-wide efforts to deter adolescents from smoking and to reduce the exposure to ETS.

  13. Ethnic Identity, Ethnic Attitudes, Self-Esteem, and Esteem toward Others among Estonian and Russian Adolescents.

    Science.gov (United States)

    Valk, Aune

    2000-01-01

    Investigated ethnic identity in relation to self-esteem and esteem toward others and attitudes toward one's own and other ethnic groups among Estonian and Russian adolescents. Found significant differences between majority and minority groups in ethnic pride and ethnic differentiation and with their correlation to self-esteem and esteem toward…

  14. The Perceived Impact of External Evaluation: The System, Organisation and Individual Levels-Estonian Case

    Science.gov (United States)

    Seema, Riin; Udam, Maiki; Mattisen, Heli; Lauri, Liia

    2017-01-01

    The purpose of this article is to provide an overview of how the employees of higher education institutions perceive the impact of external evaluations. The study was conducted using the concurrent mixed method and involved 361 employees from Estonian universities and professional higher education institutions. The results indicated that…

  15. Gender Advantages and Gender Normality in the Views of Estonian Secondary School Students

    Science.gov (United States)

    Kuurme, Tiiu; Kasemaa, Gertrud

    2015-01-01

    The aim of the study on Estonian secondary school students was to obtain an overview of the gender-related views and experiences of the everyday school life by students, and to analyse the school-related factors in the development of gender roles and gender-related expectations. We view gender equality as a central condition for social…

  16. Estonian Air võitis reisijaid juurde. Samas turuosa vähenes

    Index Scriptorium Estoniae

    2011-01-01

    Estonian Airi turuosa vähenes Tallinna lennujaamas regulaarliinidel 2010. aastal võrreldes 2009. aastaga 3,9% võrra, lende toimus 1,8% rohkem kui 2009. a. Lendude toimumise protsent oli 98,1, väljumise täpsus oli 86,7%. Andmeid ka 2010. aasta detsembrikuu kohta

  17. Estonian Air lendab üle võimete / Harry Tuul

    Index Scriptorium Estoniae

    Tuul, Harry

    2006-01-01

    Viimastel aastatel on Estonian Airil kasvanud nii lendude kui ka reisijate hulk, kuid lennukite arv on jäänud samaks. Tabel. Kaart: Lendude arv sihtkohtadesse nädalas. Kommenteerib Kristina Traks. Küsimustele vastab Mart Relve. Vt. samas: Lennukipuudus sunnib liine sulgema

  18. The Estonian diaspora in South-West Russia in the 1920—30s: migration results

    Directory of Open Access Journals (Sweden)

    Stupin Yuri

    2010-11-01

    Full Text Available This article analyses the spatial features of the settling of Russian Estonians in the Northwest region at the “zenith” of diaspora on the basis of 1920, 1926, and 1939 censuses. The author identifies the principal settling areas and points out the geographical preconditions for the rapid decline of the diaspora.

  19. Tiger in Focus--A National Survey of ICT in Estonian Schools

    Science.gov (United States)

    Toots, Anu; Laanpere, Mart

    2004-01-01

    Estonia has not participated in international studies of ICT in education, nor have there been any similar studies at the national level up until the year 2000. The first survey of ICT in Estonian schools was conducted after completion of the national school computerization programme called Tiger Leap. This paper focuses on the targeted responses…

  20. Estonian Airi ümber käib lehmakauplemine / Tõnu Lilleorg

    Index Scriptorium Estoniae

    Lilleorg, Tõnu

    2008-01-01

    Skandinaavia lennukompanii SAS saatis Eesti valitsusele kirja, milles teatab, et on nõus raskustes Estonian Airile lisainvesteeringuid tegema vaid siis, kui riik müüb SAS-ile oma osaluse, 34%. Vt. samas: SAS ei taha lennufirma eest maksta üle 150 miljoni. Diagramm: Majandusnäitajad, omanikud

  1. Technology, safety, and costs of decommissioning reference nuclear research and test reactors. Main report

    Energy Technology Data Exchange (ETDEWEB)

    Konzek, G.J.; Ludwick, J.D.; Kennedy, W.E. Jr.; Smith, R.I.

    1982-03-01

    Safety and Cost Information is developed for the conceptual decommissioning of two representative licensed nuclear research and test reactors. Three decommissioning alternatives are studied to obtain comparisons between costs (in 1981 dollars), occupational radiation doses, potential radiation dose to the public, and other safety impacts. The alternatives considered are: DECON (immediate decontamination), SAFSTOR (safe storage followed by deferred decontamination), and ENTOMB (entombment). The study results are presented in two volumes. Volume 1 (Main Report) contains the results in summary form.

  2. Task-Shifting and Quality of HIV Testing Services: Experiences from a National Reference Hospital in Zambia.

    Directory of Open Access Journals (Sweden)

    Sheila Mwangala

    Full Text Available With new testing technologies, task-shifting and rapid scale-up of HIV testing services in high HIV prevalence countries, assuring quality of HIV testing is paramount. This study aimed to explore various cadres of providers' experiences in providing HIV testing services and their understanding of elements that impact on quality of service in Zambia.Sixteen in-depth interviews and two focus group discussions were conducted with HIV testing service providers including lay counselors, nurses and laboratory personnel at purposively selected HIV testing sites at a national reference hospital in Lusaka. Qualitative content analysis was adopted for data analysis.Lay counselors and nurses reported confidentiality and privacy to be greatly compromised due to limited space in both in- and out-patient settings. Difficulties in upholding consent were reported in provider-initiated testing in in-patient settings. The providers identified non-adherence to testing procedures, high workload and inadequate training and supervision as key elements impacting on quality of testing. Difficulties related to testing varied by sub-groups of providers: lay counselors, in finger pricking and obtaining adequate volumes of specimen; non-laboratory providers in general, in interpreting invalid, false-negative and false-positive results. The providers had been participating in a recently established national HIV quality assurance program, i.e. proficiency testing, but rarely received site supervisory visits.Task-shifting coupled with policy shifts in service provision has seriously challenged HIV testing quality, protection of confidentiality and the process of informed consent. Ways to better protect confidentiality and informed consent need careful attention. Training, supervision and quality assurance need strengthening tailored to the needs of the different cadres of providers.

  3. The contribution of the Estonian Soil Sciences Society to the science, society and education

    Science.gov (United States)

    Rossner, Helis; Reintam, Endla; Astover, Alar; Shanskiy, Merrit

    2015-04-01

    Predecessor of todays Estonian Soil Science Society was Estonian Branch of All-Union Soil Society of Soil Scientist which acted from 1957 to 1991. In 1957-1964 Estonian Branch was leaded by prof. Osvald Hallik and in 1964-1991 by prof. Loit Reintam. After re-independence of Estonia in 1991 the society acted in informal way and was leaded by prof. L. Reintam. Non-profit organization "Estonian Soil Science Society" was officially (re)established in 10.23.2009. Estonian Soil Science Society (ESSS) is aimed to: • coordinate collaboration between institutions and individuals intrested of soil science, conservation and sustainable use of soils; • promoting soil science education and research, raising awareness of publicity on topics relating to soils in Estonia; • cooperation between local and foreign unions and associations. In recent years the ESSS had managed to reunite the number of soil scientist from different research institutions of Estonia and of related institutions. Also, the ESSS had provided numerous of materials based on later scientific findings. One of most important activity leaded by ESSS is the organizing Soil Day in Estonia with relevant seminar, where the speakers are sharing latest information with target group (researchers, teachers, policy makers, farmers, students etc.). In a frames of Soil Day the Soil of the Year is selected for Estonia. In 2015, the soil of the year is Leptosol. For current, International Year of the Soil ESSS had planned numerous activities to introduce the importance of soils to wider audience. In current presentation we would like to share the soil science researchers experience through- out the decades of soil science research in Estonia, show our latest findings and designed activities for the International Year of SOIL.

  4. Reference Book of Nuclear Testing Contractors 1945-1965. Revision 1

    Science.gov (United States)

    1987-05-30

    033 Plesset (E.H.) Associates, Inc. ** Los Angeles, CA DASA Radiation Inc. Orlando, FL Project 5.1 WADC AF 33(600)-19270 Radio Electronics...ARPA Nuclear Test Detection F33657-67-C-1553 AFTAC ARPA Normally directed by the Army Material Command (AMCOM) and operated by the Radio ...Corporation of Amercia Aerojet General Project 6.1 Army Electronics R&D Activity* AERO LAB Development Co. Projects 6.2 & 6.3 BRL* Projects 6.13

  5. Technology, safety, and costs of decommissioning reference nuclear research and test reactors. Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Konzek, G.J.; Ludwick, J.D.; Kennedy, W.E. Jr.; Smith, R.I.

    1982-03-01

    Safety and Cost Information is developed for the conceptual decommissioning of two representative licensed nuclear research and test reactors. Three decommissioning alternatives are studied to obtain comparisons between costs (in 1981 dollars), occupational radiation doses, potential radiation dose to the public, and other safety impacts. The alternatives considered are: DECON (immediate decontamination), SAFSTOR (safe storage followed by deferred decontamination), and EMTOMB (entombment). The study results are presented in two volumes. Volume 2 (Appendices) contains the detailed data that support the results given in Volume 1, including unit-component data.

  6. Noor eesti teater ja Noor-Eesti. Young Estonian Theatre and Young Estonia

    Directory of Open Access Journals (Sweden)

    Katri Aaslav-Tepandi

    2012-04-01

    Full Text Available This article begins by examining points of intersection between two professional theatres, ”Estonia” and ”Vanemuine” (both established in 1906, their young directors – Karl Menning, Paul Pinna, Theodor Altermann, and Karl Jungholz, and the literary movement Young Estonia. Subsequently, we will consider Young Estonia’s theatrical ideals and the influence of these ideas on later Estonian theatrical life. Since not much information has survived regarding direct personal contacts between ”movers and shakers” in the theatre world and Young Estonians, the main focus here shall be on indirect creative connections and influences. One such context is education: like the Young Estonians, theatre activists of the younger generation aspired to place themselves on the larger map of European culture. Thus, their artistic beliefs and goals shall be examined in relation to those of Young Estonians’ quest for modern culture. Pinna, Altermann, Menning, Jungholz, and others went on study tours to Germany and France, where they were energized and inspired by innovative German and Russian theatres, by naturalistic staging, and by psychological realism, both in acting and in performance style. Among their models were A. Antoine’s Théâtre- Libre in Paris, K. Stanislavski’s Art Theatre in Moscow, O. Brahm’s Lessing-Theater, and M. Reinhardt’s Deutsches Theater in Berlin. These models were likewise known to the Young Estonians, but if theatre activists oriented themselves more fundamentally to German naturalist and realist dramatic art, Young Estonians were more taken with ”theatrical theatre” with its symbolist and impressionist influences. The Young Estonians attended performances at both theatres, ”Vanemuine” and ”Estonia”, and wrote numerous theatre reviews. Yet in the Young Estonia albums (yearbooks and in the magazine Young Estonia, theatre topics have a relatively modest representation. Young Estonians did not have direct

  7. [Encapsulated voices : Estonian sound recordings from the German prisoner-of-war camps in 1916-1918] / Tõnu Tannberg

    Index Scriptorium Estoniae

    Tannberg, Tõnu, 1961-

    2013-01-01

    Arvustus: Encapsulated voices : Estonian sound recordings from the German prisoner-of-war camps in 1916-1918 (Das Baltikum in Geschichte und Gegenwart, 5). Hrsg. von Jaan Ross. Böhlau Verlag. Köln, Weimar und Wien 2012

  8. Estonian Business Schooli magistriharidus nüüd ka koju kätte / Madis Habakuk

    Index Scriptorium Estoniae

    Habakuk, Madis

    2007-01-01

    Sügisest hakkab Estonian Business School koos Mainori Kõrgkooliga pakkuma magistriõpet majandushariduseta inimestele, kus soovijatel on võimalus õppida EBSi Master of Business Administration programmi järgi

  9. The State, the Museum and the Ethnographer in Constructing National Heritage: Defining Estonian National Costumes in the 1930s

    Directory of Open Access Journals (Sweden)

    Marleen Nõmmela

    2011-03-01

    Full Text Available In this article I attempt to analyse the way in which the Estonian national costume, as heritage, was defined through the cooperation of the state, the museum and ethnographers in the 1930s. The nationalist state wished to strengthen the national identity of Estonia. The Estonian National Museum (ENM as a repository of memory and knowledge availed its resources to support cultural propaganda. The ethnographer Helmi Kurrik, a woman of strong will and keen interest in folk textiles, managed to fulfil her obligation at the expense of her own health. The primary result of her labours was a handbook entitled Eesti rahvarõivad (Estonian Folk Costumes (1938 which has influenced general knowledge of folk costumes in Estonia up to the present day – the ‘right’ national costumes are believed to derive from authentic ethnographical folk costumes held in the Estonian National Museum.

  10. The Rocky Road towards Professional Autonomy: The Estonian Journalists’ Organization in the Political Turmoil of the 20th Century

    Directory of Open Access Journals (Sweden)

    Epp Lauk

    2017-09-01

    Full Text Available This article attempts to explain the relationships between journalists, politics and the state from the perspective of collective autonomy, that of the professional organization of journalists. The case of Estonian Journalists’ Union demonstrates the complexity and historical contingency of professional autonomy of journalism. The development of the Estonian journalists’ organization occurred as a sequence of transformations from the Estonian Journalists’ Association to the Estonian Journalists’ Union to the Soviet type journalists’ union, and lastly to an independent trade union. This sequence was disrupted by several fatal breakdowns that changed not only the character of the association, but also professional values, the whole occupational ideology and the conditions of the existence of journalism as a profession in Estonia.

  11. Väärikas Estonian Air jäi kampaaniaga hätta / Alyona Stadnik

    Index Scriptorium Estoniae

    Stadnik, Alyona

    2010-01-01

    Estonian Air müüs veebikaupluse cherry.ee kaudu soodsaid kinkekaarte. Vastuolu tekkis asjaolust, et nõudlus kinkekaartide järele oli suurem kui pakkumine. Lennukompanii katkestas soodsate kinkekaartide müügi

  12. Kanada rahastaja tõi Estonian Airi ostu lähemale / Rivo Sarapik ; kommenteerinud Andrus Ansip

    Index Scriptorium Estoniae

    Sarapik, Rivo, 1981-

    2010-01-01

    Estonian Air ja Bombardier sõlmisid lennukite hanke lepingu, tingimused ja hind jäid samaks, muutus vaid lennukite tarneaeg. Ostu rahastab Kanada finantseerimisasutus. Uued lennukid saabuvad Eestisse 2011. a. jaanuaris

  13. Omaeluloolisus eesti teatris: Merle Karusoo lavastustest. Life Narratives and Estonian Theatre: The Productions of Merle Karusoo

    Directory of Open Access Journals (Sweden)

    Piret Kruuspere

    2012-04-01

    Full Text Available Any consideration of Estonian theatre from the point of view of biographical theatre needs to include the work of playwright and director Merle Karusoo. Productions based on various life narratives (diaries, letters, biographical interviews form the core of her work that can be defined as biographical or memory theatre. Her work has also been viewed within the context of community theatre or political theatre; Karusoo has herself referred to her work as sociological theatre. Life narratives have functioned in Karusoo’s productions as the basis for restoring oppressed or denied collective discourses of memory. Her productions emerged within the framework of the more general process of restoration of historical heritage and the rehabilitation of collective memory at the end of the 1980s and the beginning of the 1990s. Life story can be viewed as the essence of Merle Karusoo’s theatre. The personal in the life story in the production activates the emotional memory of the audience; for older generations such theatre facilitates a legitimisation of remembering one’s life story in entirety, and for younger generations it functions as a vehicle of collective, historical and national memory. The current article outlines the main stages of Karusoo’s biographical theatre, highlights major productions of each stage and provides an overview of their reception. Karusoo’s theatre dates back to 1980s. Productions based on life stories of the generations born in 1950s and 1960s, Meie elulood (Our Biographies and Kui ruumid on täis ... (Full Rooms both in 1982, mediated fragments of life stories of 16 drama students, focusing on the processes of self-conception and -reflection of young persons. In the context of the Soviet regime that exerted firm ideological control over the private lives of its citizens, Karusoo’s productions struck an especially powerful and unusual chord. Karusoo’s biographical theatre has gathered momentum and assumed a more

  14. In situ carcinoma of the esophagus. Macroscopic study with particular reference to the Lugol test.

    Science.gov (United States)

    Mandard, A M; Tourneux, J; Gignoux, M; Blanc, L; Segol, P; Mandard, J C

    1980-03-01

    The results presented here concern the study of in situ cancer and marked dysplasia revealed during the pathological study of 39 specimens removed during esophagogastrectomy for invasive carcinoma of the esophagus. In 12 cases, macroscopic study made it possible to define precisely the macroscopic features of in situ canccer; in one case, however, the mucous membrane at the site of the in situ cancer was macroscopically normal. The iodine test performed in 37 cases showed that the normal esophageal mucosa is iodine-positive and that in situ and invasive squamous cell carcinoma are always represented by sharply defined iodine-negative zones: in the case in which it was sufficiently extensive, marked dysplasia presented the same iodine-negative character. The possibilities for applying these results to early endoscopic diagnosis of esophageal cancer are presented.

  15. Development and Implementation of a Coagulation Factor Testing Method Utilizing Autoverification in a High-volume Clinical Reference Laboratory Environment.

    Science.gov (United States)

    Riley, Paul W; Gallea, Benoit; Valcour, Andre

    2017-01-01

    Testing coagulation factor activities requires that multiple dilutions be assayed and analyzed to produce a single result. The slope of the line created by plotting measured factor concentration against sample dilution is evaluated to discern the presence of inhibitors giving rise to nonparallelism. Moreover, samples producing results on initial dilution falling outside the analytic measurement range of the assay must be tested at additional dilutions to produce reportable results. The complexity of this process has motivated a large clinical reference laboratory to develop advanced computer algorithms with automated reflex testing rules to complete coagulation factor analysis. A method was developed for autoverification of coagulation factor activity using expert rules developed with on an off the shelf commercially available data manager system integrated into an automated coagulation platform. Here, we present an approach allowing for the autoverification and reporting of factor activity results with greatly diminished technologist effort. To the best of our knowledge, this is the first report of its kind providing a detailed procedure for implementation of autoverification expert rules as applied to coagulation factor activity testing. Advantages of this system include ease of training for new operators, minimization of technologist time spent, reduction of staff fatigue, minimization of unnecessary reflex tests, optimization of turnaround time, and assurance of the consistency of the testing and reporting process.

  16. The eye of the red-eared slider turtle: morphologic observations and reference values for selected ophthalmic diagnostic tests.

    Science.gov (United States)

    Somma, André T; Lima, Leandro; Lange, Rogério R; Turner-Giannico, Amália; Montiani-Ferreira, Fabiano

    2015-01-01

    To perform a descriptive investigation of the red-eared slider turtle (Trachemys scripta elegans) eye, performing selected ophthalmic diagnostic tests with the aim of establishing normal reference values for this species. Thirty adult healthy red-eared slider turtles were used to establish normal ophthalmic test values in this investigation. Selected ophthalmic tests included: collection of material for bacterial culture analysis, esthesiometry, intraocular pressure (IOP), A- and B-mode ultrasonic biometry, fundus photography, and central corneal thickness (CCT). Normal parameters found for the ocular diagnostic tests were: esthesiometry: 5.84 ± 0.48 cm; IOP: 5.42 ± 1.70 mmHg; CCT: 154.5 ± 0.14 μm; palpebral fissure length: 9.71 ± 0.55 mm; modified Schirmer tear test: 2.55 ± 3.4 mm; globe axial length: 7.60 ± 0.23 mm; anterior chamber depth: 0.76 ± 0.23 mm; lens axial length: 2.45 ± 0.28 mm; vitreous chamber depth: 4.31 ± 0.42 mm. An avascular retinal pattern with nerve fibers radiating from the small white circular optic disk was observed. None of the animals had a conus papillaris. The most frequent bacteria found were Bacillus spp. (33.33%) followed by Proteus vulgaris (20.69%) and Staphylococcus aureus (18.39%). No significant differences between left and right eyes or genders were found for any of the results. Reference data and morphologic observations obtained in this investigation might help veterinary ophthalmologists to diagnose ocular diseases in the red-eared slider turtle. © 2014 American College of Veterinary Ophthalmologists.

  17. MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies.

    Science.gov (United States)

    Haller, Toomas; Leitsalu, Liis; Fischer, Krista; Nuotio, Marja-Liisa; Esko, Tõnu; Boomsma, Dorothea Irene; Kyvik, Kirsten Ohm; Spector, Tim D; Perola, Markus; Metspalu, Andres

    2017-01-01

    Ancestry information at the individual level can be a valuable resource for personalized medicine, medical, demographical and history research, as well as for tracing back personal history. We report a new method for quantitatively determining personal genetic ancestry based on genome-wide data. Numerical ancestry component scores are assigned to individuals based on comparisons with reference populations. These comparisons are conducted with an existing analytical pipeline making use of genotype phasing, similarity matrix computation and our addition-multidimensional best fitting by MixFit. The method is demonstrated by studying Estonian and Finnish populations in geographical context. We show the main differences in the genetic composition of these otherwise close European populations and how they have influenced each other. The components of our analytical pipeline are freely available computer programs and scripts one of which was developed in house (available at: www.geenivaramu.ee/en/tools/mixfit).

  18. First definition of reference intervals of liver function tests in China: a large-population-based multi-center study about healthy adults.

    Science.gov (United States)

    Mu, Runqing; Chen, Wenxiang; Pan, Baishen; Wang, Lanlan; Hao, Xiaoke; Huang, Xianzhang; Qiao, Rui; Zhao, Min; Zhang, Chuanbao; Guo, Wei; Huang, Hengjian; Ma, Yueyun; Zhuang, Junhua; Zhang, Jie; Shang, Hong

    2013-01-01

    Reference intervals of Liver function tests are very important for the screening, diagnosis, treatment, and monitoring of liver diseases. We aim to establish common reference intervals of liver function tests specifically for the Chinese adult population. A total of 3210 individuals (20-79 years) were enrolled in six representative geographical regions in China. Analytes of ALT, AST, GGT, ALP, total protein, albumin and total bilirubin were measured using three analytical systems mainly used in China. The newly established reference intervals were based on the results of traceability or multiple systems, and then validated in 21 large hospitals located nationwide qualified by the National External Quality Assessment (EQA) of China. We had been established reference intervals of the seven liver function tests for the Chinese adult population and found there were apparent variances of reference values for the variables for partitioning analysis such as gender(ALT, GGT, total bilirubin), age(ALP, albumin) and region(total protein). More than 86% of the 21 laboratories passed the validation in all subgroup of reference intervals and overall about 95.3% to 98.8% of the 1220 validation results fell within the range of the new reference interval for all liver function tests. In comparison with the currently recommended reference intervals in China, the single side observed proportions of out of range of reference values from our study for most of the tests deviated significantly from the nominal 2.5% such as total bilirubin (15.2%), ALP (0.2%), albumin (0.0%). Most of reference intervals in our study were obviously different from that of other races. These used reference intervals are no longer applicable for the current Chinese population. We have established common reference intervals of liver function tests that are defined specifically for Chinese population and can be universally used among EQA-approved laboratories located all over China.

  19. The reference peak areas of the 1995 IAEA test spectra for gamma-ray spectrum analysis programs are absolute and traceable

    CERN Document Server

    Blaauw, M

    1999-01-01

    A previously validated algorithm for absolute peak area determination was used to verify the reference peak areas supplied with the 1995 IAEA test spectra for gamma-ray spectrometry. These reference peak areas turn out to be absolute and traceable to a precision of 0.9%: The reference peak areas are possibly too low by a factor 0.992+-0.009. It is proposed to employ the test spectra and reference areas to validate the peak areas obtained with any algorithm in gamma-ray spectrometry. (author)

  20. Fool's Gold: Why Imperfect Reference Tests Are Undermining the Evaluation of Novel Diagnostics: A Reevaluation of 5 Diagnostic Tests for Leptospirosis

    Science.gov (United States)

    Limmathurotsakul, Direk; Turner, Elizabeth L.; Wuthiekanun, Vanaporn; Thaipadungpanit, Janjira; Suputtamongkol, Yupin; Chierakul, Wirongrong; Smythe, Lee D.; Day, Nicholas P. J.; Cooper, Ben; Peacock, Sharon J.

    2012-01-01

    Background. We observed that some patients with clinical leptospirosis supported by positive results of rapid tests were negative for leptospirosis on the basis of our diagnostic gold standard, which involves isolation of Leptospira species from blood culture and/or a positive result of a microscopic agglutination test (MAT). We hypothesized that our reference standard was imperfect and used statistical modeling to investigate this hypothesis. Methods. Data for 1652 patients with suspected leptospirosis recruited during three observational studies and one randomized control trial that described the application of culture, MAT, immunofluorescence assay (IFA), lateral flow (LF) and/or PCR targeting the 16S rRNA gene were reevaluated using Bayesian latent class models and random-effects meta-analysis. Results. The estimated sensitivities of culture alone, MAT alone, and culture plus MAT (for which the result was considered positive if one or both tests had a positive result) were 10.5% (95% credible interval [CrI], 2.7%–27.5%), 49.8% (95% CrI, 37.6%–60.8%), and 55.5% (95% CrI, 42.9%–67.7%), respectively. These low sensitivities were present across all 4 studies. The estimated specificity of MAT alone (and of culture plus MAT) was 98.8% (95% CrI, 92.8%–100.0%). The estimated sensitivities and specificities of PCR (52.7% [95% CrI, 45.2%–60.6%] and 97.2% [95% CrI, 92.0%–99.8%], respectively), lateral flow test (85.6% [95% CrI, 77.5%–93.2%] and 96.2% [95% CrI, 87.7%–99.8%], respectively), and immunofluorescence assay (45.5% [95% CrI, 33.3%–60.9%] and 96.8% [95% CrI, 92.8%–99.8%], respectively) were considerably different from estimates in which culture plus MAT was considered a perfect gold standard test. Conclusions. Our findings show that culture plus MAT is an imperfect gold standard against which to compare alterative tests for the diagnosis of leptospirosis. Rapid point-of-care tests for this infection would bring an important improvement

  1. Couples’ Educational Needs Referred to Ershad and Fazel Health Centers of Tehran for Pre-marriage Tests in 2014

    Directory of Open Access Journals (Sweden)

    ّFarima Mohammadi

    2016-12-01

    Full Text Available Background and Objective: Premarital education is the foundation for the development of couples’ communications, sexual relationships, health and fertility. Therefore, this study was done with the purpose of determining couples’ educational needs referred to Ershad and Fazel health centers of Tehran for pre-marriage tests.Materials and Methods: A Cross Sectional study was conducted among couples who referred to health centers. The sample size was 1672 and the sampling method was convenience.. Demographic data was collected through interview with women based on questionnaires. Then the couples responded to the self-administered educational needs questionnaire. The collected data were entered into SPSS-21 statistical software and analyzed using Chi-Square test.Results: 883 women and 789 men completed the educational needs questionnaire. The mean (SD age of women and men were 27.1 (4.5 and 30.2 (5.3 years respectively. Of all female participants 483 (54.7% and 369 (41.8% of male participants had a bachelor's degree. 97.5% of men and 57.1% of women were employed. The ethnicity of about 72% of participants was Far. Most of the pre-marriage educational needs of men and women were marital health, importance of pre-marriage tests, unintended pregnancy prevention methods, correct marital relationship and prenatal care. 313 (64.6% women and 238 (42.8% men reported the pre-marriage educational class to be very helpful. The educational needs of couples were not different based on education, ethnicity and place of residence.Conclusion: Results of the currents study shows the need for pre-marriage education in all evaluated aspects and the importance of paying attention to it for prospering the pre-marital classes.

  2. The trade-off between money and time: A test of the theory of reference-dependent preferences

    DEFF Research Database (Denmark)

    De Borger, Bruno; Fosgerau, Mogens

    2008-01-01

    We formulate a model of reference-dependent preferences based on the marginal rate of substitution at the reference-point of a reference-free utility function. Using binary choices on the trade-off between money and travel time, reference-dependence is captured by value functions that are centere...

  3. Reliability of different mark-recapture methods for population size estimation tested against reference population sizes constructed from field data.

    Directory of Open Access Journals (Sweden)

    Annegret Grimm

    Full Text Available Reliable estimates of population size are fundamental in many ecological studies and biodiversity conservation. Selecting appropriate methods to estimate abundance is often very difficult, especially if data are scarce. Most studies concerning the reliability of different estimators used simulation data based on assumptions about capture variability that do not necessarily reflect conditions in natural populations. Here, we used data from an intensively studied closed population of the arboreal gecko Gehyra variegata to construct reference population sizes for assessing twelve different population size estimators in terms of bias, precision, accuracy, and their 95%-confidence intervals. Two of the reference populations reflect natural biological entities, whereas the other reference populations reflect artificial subsets of the population. Since individual heterogeneity was assumed, we tested modifications of the Lincoln-Petersen estimator, a set of models in programs MARK and CARE-2, and a truncated geometric distribution. Ranking of methods was similar across criteria. Models accounting for individual heterogeneity performed best in all assessment criteria. For populations from heterogeneous habitats without obvious covariates explaining individual heterogeneity, we recommend using the moment estimator or the interpolated jackknife estimator (both implemented in CAPTURE/MARK. If data for capture frequencies are substantial, we recommend the sample coverage or the estimating equation (both models implemented in CARE-2. Depending on the distribution of catchabilities, our proposed multiple Lincoln-Petersen and a truncated geometric distribution obtained comparably good results. The former usually resulted in a minimum population size and the latter can be recommended when there is a long tail of low capture probabilities. Models with covariates and mixture models performed poorly. Our approach identified suitable methods and extended options to

  4. Strategies for Estonian rural family enterprises. Eesti maapiirkonna pereettevõtete strateegia

    Directory of Open Access Journals (Sweden)

    Maret Kirsipuu

    2013-01-01

    Full Text Available The paper seeks to analyse family businesses in rural areas, family business strategies and re-registration of sole proprietors with the Centre of Registers and Information Systems (hereinafter Commercial Register in 2009, and to provide an overview of entrepreneurship policies targeted at Estonian rural businesses. Layoffs have increased the number of unemployed; some of those who have lost employment opt for social assistance benefits, but some others decide to become entrepreneurs. Many enterprising people in Estonia have set up a family enterprise, mainly in the sphere of services, agriculture and tourism. The Estonian entrepreneurship policy supports enterprising people and approves of entrepreneurship as a promoter of national economic development. One of the most positive qualities of family enterprises is their short decision-making chain, which ensures rapid implementation of the strategy.

  5. The Role of Language in (Recreating Tatar Diaspora Identity: the Case of the Estonian Tatars

    Directory of Open Access Journals (Sweden)

    Maarja Klaas

    2015-06-01

    Full Text Available This paper focuses on the meanings assigned to Tatar language among the Tatar diaspora in Estonia. According to interviews with Estonian Tatars as well as descriptions of field material from Tatarstan, language is an important aspect of Tatar ethnic identity. This paper will track common discourses about the Tatar language and the way it is connected to Tatar ethnic identity. Issues concerning Tatar language are used to demonstrate various ways of enacting Tatarness in Estonia. It is shown that Estonian Tatars worry about the vitality and purity of Tatar language, but for some, marginalization of dialects is also an issue. People categorized with the same identity labels by self and others can experience and enact their Tatarness in a variety of different ways.

  6. The Role of Language in (Recreating Tatar Diaspora Identity: The Case of the Estonian Tatars

    Directory of Open Access Journals (Sweden)

    Maarja Klaas

    2015-06-01

    Full Text Available This paper focuses on the meanings assigned to Tatar language among the Tatar diaspora in Estonia. According to interviews with Estonian Tatars as well as descriptions of field material from Tatarstan, language is an important aspect of Tatar ethnic identity. This paper will track common discourses about the Tatar language and the way it is connected to Tatar ethnic identity. Issues concerning Tatar language are used to demonstrate various ways of enacting Tatarness in Estonia. It is shown that Estonian Tatars worry about the vitality and purity of Tatar language, but for some, marginalization of dialects is also an issue. People categorized with the same identity labels by self and others can experience and enact their Tatarness in a variety of different ways.

  7. Variability of Temperature and Its Impact on Reference Evapotranspiration: The Test Case of the Apulia Region (Southern Italy

    Directory of Open Access Journals (Sweden)

    Abderraouf Elferchichi

    2017-12-01

    Full Text Available The present study provides an assessment of the climate variability at a subnational scale, focusing on the case of the Apulia region, in Southeastern Italy. The variables considered for the purpose of a trend analysis were the minimum, maximum, and mean temperatures, and reference evapotranspiration. These are very important in an urban–rural planning context. The study was based on 38 monitoring stations and consisted in the application of the nonparametric Mann–Kendall test and a progressive trend analysis, both used to detect the changes. The 1950–2003 period was investigated on seasonal and annual scales. The results generally showed a warming process and an acceleration of the atmospheric evaporative demand which took place especially since the mid-1970s. The latter had a significant positive trend, while the period before the break point of the 70s had a cooling effect. Finally, the warming effect was more pronounced for minimum temperatures.

  8. Potassium Dichromate as a Reference Substance for Embryonic Tests of Toxicity in the Common Carp (Cyprinus carpio L.

    Directory of Open Access Journals (Sweden)

    R. Krejčí

    2006-01-01

    Full Text Available Potassium dichromate (K2Cr2O7 has already been used as a reference substance in tests of toxicity with aquatic animals. The aim of this study was to determine and compare values of LC50 for potassium dichromate during the whole period of embryonic development (i.e., 120 h and 48 h after hatching of embryos in the common carp (Cyprinus carpio L.. Fish eggs and embryos were exposed to 5 different concentrations of potassium dichromate (i.e., 372, 409, 450, 495, 545 mg l-1 during two experiments. Such characteristics as the cumulative mortality, the start and the end of hatching, the number of deformities, body length, and body mass of surviving individuals were studied during the tests. The highest mortality was found in the hatched embryos. Mortality and frequency of deformities increased with the growing concentration of potassium dichromate. The value of 120 LC50 for potassium dichromate was 464.91 ± 23.83 mg l-1 and the value of 48 LC50 was 458.94 ± 4.14 mg l-1 (mean ± SD. No statistically significant difference between values 120 LC50 a 48 LC50 was found. This is why reduction of the exposure period to only 48 h after hatching seems a reasonable method to study the control of susceptibility using potassium dichromate in embryonic tests of toxicity.

  9. Serological evidence of exposure to globally relevant zoonotic parasites in the Estonian population

    DEFF Research Database (Denmark)

    Lassen, Brian; Janson, Marilin; Viltrop, Arvo

    2016-01-01

    We investigated Estonian population and its selected subgroups for serological evidence of exposure to Ascaris lumbricoides, Echinococcus spp., Taenia solium, Toxocara canis, Toxoplasma gondii, and Trichinella spiralis. Serum samples from 999 adults representing general population, 248 children...... spp. seroprevalence was higher in children. By contrast, T. gondii seroprevalence was higher in animal caretakers, and lower in children, than in the general population. In the general population, the WB-confirmed Echinococcus spp. seroprevalence was 0.5%, T. solium cysticercosis seroprevalence was 0...

  10. Job satisfaction and organizational trust as antecedents of organizational commitment in Finnish and Estonian SMEs

    OpenAIRE

    Kemell, Kirsi

    2015-01-01

    This empirical study examines three well-known leadership themes – organizational commitment, job satisfaction and organizational trust – from the perspective of Finnish and Estonian small and medium –sized enterprises (SMEs). The object of the study is to increase knowledge about organizational commitment and job attitudes affecting the formation of commitment. The study is cross-sectional, using previously gathered SME survey data. Organizational commitment is understood as a multidime...

  11. Short outlines of books by Estonian authors : [annotations] / Rutt Hinrikus, Janika Kronberg

    Index Scriptorium Estoniae

    Hinrikus, Rutt, 1946-

    1998-01-01

    Laretei, Käbi. Eksiil; Toona, Elin. Lotukata; Park, Eeva. Naeru õpilane; Luik, Viivi. Inimese kapike; Laaman, Ilona. Vesi ahjus; Viiding, Juhan (Üdi, Jüri). Kogutud luuletused; Paju, Juhan. Katkenud romaan; Paju, Juhan. Hõõguv rist; Estonian short stories / toim. Kajar Pruul ja Darlene Reddaway; Traat, Mats. Kartaago kiirrong; Kauksi Ülle. Säng; Kross, Jaan. Paigallend; Puhvel, Madli. Symbol of dawn; Kaplinski, Jaan. Võimaluste võimalikkus; Kaplinski, Jaan. Usk on uskmatus

  12. Comparison of six-minute walk test in children with moderate/severe asthma with reference values for healthy children

    Directory of Open Access Journals (Sweden)

    Lívia Barboza de Andrade

    2014-06-01

    Full Text Available OBJECTIVE: to compare physical performance and cardiorespiratory responses in the six-minute walk test (6MWT in asthmatic children with reference values for healthy children in the same age group, and to correlate them with intervening variables. METHODS: this was a cross-sectional, prospective study that evaluated children with moderate/severe asthma, aged between 6 and 16 years, in outpatient follow-up. Demographic and spirometric test data were collected. All patients answered the pediatric asthma quality of life (QoL questionnaire (PAQLQ and level of basal physical activity. The 6MWT was performed, following the American Thoracic Society recommendations. Comparison of means was performed using Student's t-test and Pearson's correlation to analyze the 6MWT with study variables. The significance level was set at 5%. RESULTS: 40 children with moderate or severe asthma were included, 52.5% males, 70% with normal weight and sedentary. Mean age was 11.3 ± 2.1 years, mean height was 1.5 ± 0.1 m, and mean weight was 40.8 ± 12.6 Kg. The mean distance walked in the 6MWT was significantly lower, corresponding to 71.9% ± 19.7% of predicted values; sedentary children had the worst values. The difference between the distance walked on the test and the predicted values showed positive correlation with age (r = 0.373, p = 0.018 and negative correlation with cardiac rate at the end of the test (r = -0.518, p < 0.001. Regarding QoL assessment, the values in the question about physical activity limitations showed the worst scores, with a negative correlation with walked distance difference (r = -0.311, p = 0.051. CONCLUSIONS: asthmatic children's performance in the 6MWT evaluated through distance walked is significantly lower than the predicted values for healthy children of the same age, and is directly influenced by sedentary life style.

  13. Cancer incidence and thyroid disease among Estonian Chernobyl clean-up workers

    Energy Technology Data Exchange (ETDEWEB)

    Auvinen, A.; Salomaa, S. [eds.] [Radiation and Nuclear Safety Authority, Helsinki (Finland); Rahu, M.; Veidebaum, T.; Tekkel, M. [eds.] [Inst. of Experimental and Clinical Medicine, Tallinn (Estonia); Hakulinen, T. [ed.] [Finnish Cancer Registry, Helsinki (Finland); Boice, J.D. Jr. [ed.] [Int. Epidemiology Inst., MD (United States)

    1998-09-01

    The report describes the development and summarizes the results of the project Cancer incidence and thyroid disease among Estonian Chernobyl clean-up workers. One of the goals of the report is to give research protocols and questionnaires for researchers involved in other studies. Eight previously published articles are also included summarizing the results. The development of the collaboration work of the project is described in the introduction of the report. Epidemiological methods are described in an article complemented by the protocol and English version of the questionnaire administered to all cleanup workers, as well as the data collection form of the thyroid study. The results from biological biodosimetry using both glycophorin A and FISH methods have shown that the radiation doses received by the Chernobyl cleanup workers were relatively low. Thyroid nodularity was not associated with any radiation exposure characteristic in the thyroid screening study. Estonian Chernobyl cleanup workers were followed up for cancer incidence through the Estonian Cancer Registry. No cases of leukemia or thyroid cancer were observed by the end of 1993. It is too early to observe possible effect on other types of cancer. However, mortality from suicides was increased compared with general population. Further follow-up and the extension to other Baltic countries in the future will undoubtedly strengthen the study. There are also plans for future projects covering areas from psychosocial factors to radiation biology

  14. Estonian folk traditional experiences on natural anticancer remedies: from past to the future.

    Science.gov (United States)

    Sak, Katrin; Jürisoo, Kadi; Raal, Ain

    2014-07-01

    Despite diagnostic and therapeutic advancements, the burden of cancer is still increasing worldwide. Toxicity of current chemotherapeutics to normal cells and their resistance to tumor cells highlights the urgent need for new drugs with minimal adverse side effects. The use of natural anticancer agents has entered into the area of cancer research and increased efforts are being made to isolate bioactive products from medicinal plants. To lead the search for plants with potential cytotoxic activity, ethnopharmacological knowledge can give a great contribution. Therefore, the attention of this review is devoted to the natural remedies traditionally used for the cancer treatment by Estonian people over a period of almost 150 years. Two massive databases, the first one stored in the Estonian Folklore Archives and the second one in the electronic database HERBA ( http://herba.folklore.ee/ ), containing altogether more than 30 000 ethnomedicinal texts were systematically reviewed to compile data about the Estonian folk traditional experiences on natural anticancer remedies. As a result, 44 different plants with potential anticancer properties were elicited, 5 of which [Angelica sylvestris L. (Apiaceae), Anthemis tinctoria L. (Asteraceae), Pinus sylvestris L. (Pinaceae), Sorbus aucuparia L. (Rosaceae), and Prunus padus L. (Rosaceae)] have not been previously described with respect to their tumoricidal activities in the scientific literature, suggesting thus the potential herbal materials for further investigations of natural anticancer compounds.

  15. Some remarks on reported evidentiality in French and in Estonian: A contrastive approach

    Directory of Open Access Journals (Sweden)

    Anu Treikelder

    2010-05-01

    Full Text Available Among the multiple meanings of the French conditional, the marking of mediated information is generally pointed out in the studies treating this mood in French. In Estonian there is a specialized grammatical(ized form for marking reported evidentiality – the quotative mood. Our paper aims to study the contrast between the use of evidentiality strategies in French and Estonian. The analysis will be based on a translated parallel corpus and on different types of texts and studies of monolingual corpora of both languages.In typological studies the French conditional and the Estonian grammatical evidentials are considered as belonging to the same type of evidentiality, that of reported information (Aikhenvald 2006. However, it appears that they tend to be used in different types of discourse. This observation has served as a starting point for our study: the aim of our contrastive analysis is to find out whether these divergences are confirmed by translated texts, whether they also reveal semantic differences between these evidentiality markers, and which strategies are used in the translations in both directions.

  16. Macrostructure in the narratives of Estonian children with typical development and language impairment.

    Science.gov (United States)

    Soodla, Piret; Kikas, Eve

    2010-10-01

    This study examined the macrostructure in Estonian children's narratives according to the story grammar (SG) model. The study's aims were to determine whether differences exist in narrative macrostructure between Estonian- and English-speaking children, among typically developed (TD) children, and between children with and without language impairment (LI). A clinical group of 18 children with LI (ages 6-8) and a control group of 216 TD children (ages 6-7), divided into 3 language competence subgroups, participated in the study. Narratives were analyzed for the presence of SG components and quantity of story information units. Estonian children's narratives reflected age-expected SG structures similar to those of children in English-speaking countries. The analyses revealed significant group influences for the setting category, demonstrating the superior skills of TD children with high language competence in starting stories, compared with their peers. The quantity of story information units differed significantly between the high and low language competence TD subgroups, likewise between the control and the clinical groups. The contrasts between stories of TD children and between TD and LI children are discussed. The findings support the suitability of the SG model in terms of quantity of story information units for language assessment.

  17. Pilk ingliskeelse kirjanduse tõlgetele 18. sajandi lõpust 20. sajandi algusveerandini / A Look at Estonian Translations of English Literature from the late 18th Century to the Early 20th Century

    Directory of Open Access Journals (Sweden)

    Krista Mits

    2012-06-01

    of  English  literature  were  still  made  via  German and, to a lesser extent, via Russian, Swedish or Finnish. Thus, English literature often reached the Estonian audiences in a mediated form. The selection of authors and books, the structure of the texts and the overall meaning and tone of the texts often depended on the mediating text or culture. However, many changes were made by the translator: explanations of new words and phrases, pronunciations, references to the Estonian reader, etc. Here paratexts are quite important: the titles often explained the content or the purpose of the book and referred to the language from which the book was translated. In the prefaces, translators or publishers explained their aims or connected the book to discussions in society (e.g. the translator of Uncle Tom’s Cabin connected it to anabolitionist argument of slavery as a moral evil; on the other hand, the editor connected it to the Estonian fight for freedom; the translation of The Pathfinder was related to the polemics in the Estonian newspapers over migration. However, in very many cases it was difficult to positively identify the mediating or source language or text and to establish whether it was a translation of English literature.

  18. How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs.

    Science.gov (United States)

    Lim, Cherry; Paris, Daniel H; Blacksell, Stuart D; Laongnualpanich, Achara; Kantipong, Pacharee; Chierakul, Wirongrong; Wuthiekanun, Vanaporn; Day, Nicholas P J; Cooper, Ben S; Limmathurotsakul, Direk

    2015-01-01

    The indirect immunofluorescence assay (IFA) is considered a reference test for scrub typhus. Recently, the Scrub Typhus Infection Criteria (STIC; a combination of culture, PCR assays and IFA IgM) were proposed as a reference standard for evaluating alternative diagnostic tests. Here, we use Bayesian latent class models (LCMs) to estimate the true accuracy of each diagnostic test, and of STIC, for diagnosing scrub typhus. Data from 161 patients with undifferentiated fever were re-evaluated using Bayesian LCMs. Every patient was evaluated for the presence of an eschar, and tested with blood culture for Orientia tsutsugamushi, three different PCR assays, IFA IgM, and the Panbio IgM immunochromatographic test (ICT). True sensitivity and specificity of culture (24.4% and 100%), 56kDa PCR assay (56.8% and 98.4%), 47kDa PCR assay (63.2% and 96.1%), groEL PCR assay (71.4% and 93.0%), IFA IgM (70.0% and 83.8%), PanBio IgM ICT (72.8% and 96.8%), presence of eschar (42.7% and 98.9%) and STIC (90.5% and 82.5%) estimated by Bayesian LCM were considerably different from those obtained when using STIC as a reference standard. The IgM ICT had comparable sensitivity and significantly higher specificity compared to IFA (p=0.34 and p<0.001, respectively). The low specificity of STIC was caused by the low specificity of IFA IgM. Neither STIC nor IFA IgM can be used as reference standards against which to evaluate alternative diagnostic tests. Further evaluation of new diagnostic tests should be done with a carefully selected set of diagnostic tests and appropriate statistical models.

  19. Wheezing in relation to atopy and environmental factors in Estonian and Swedish schoolchildren.

    Science.gov (United States)

    Annus, T; Björkstén, B; Mai, X M; Nilsson, L; Riikjärv, M A; Sandin, A; Bråbäck, L

    2001-12-01

    The prevalence of asthma and allergic diseases is significantly lower in post socialist Eastern Europe than in Western industrialized countries. The reason for this difference is largely unknown. Different types of childhood wheezing could be related to different risk factors. To compare the prevalence of respiratory symptoms, asthma and atopic diseases among Estonian and Swedish schoolchildren and to evaluate characteristics for wheezing in the two countries. In a prevalence study, population-based random samples of 10-11-year-old schoolchildren in Tallinn (n = 979), Estonia and in Linköping (n = 911) and Ostersund (n = 1197), Sweden were studied by a parental questionnaire and skin prick tests (SPT). All 275 children with wheeze in the past 12 months and 710 randomly selected controls within the original cohorts were invited to a case-control study involving a parental questionnaire, examination for flexural dermatitis and bronchial challenge with hypertonic saline. The study adhered to the International Study of Asthma and Allergies in Childhood (ISAAC) Phase II protocol. The prevalence of current wheezing was similar (8-10%) in the three centres, while diagnosed asthma and atopic symptoms were more common in Sweden and cold-related respiratory symptoms were more prevalent in Estonia. Frequent wheezing was more common in Sweden than in Estonia (but significantly so only in Ostersund). Wheezing children in Sweden had a high rate of positive SPT (49% in Linköping and 58% in Ostersund) bronchial hyper-responsiveness (BHR) (48% in Linköping and Ostersund) and anti-asthmatic treatment (63% in Linköping and 81% in Ostersund). In Estonia, the proportion of wheezing children with positive SPT, BHR and anti-asthmatic treatment was only 26%, 13% and 17%, respectively. Domestic crowding was inversely related to wheezing in one of the study areas (Ostersund). The mean baseline forced expiratory volume in one second (FEV1) was higher in Estonia than in Sweden, both in

  20. On-farm mortality, causes and risk factors in Estonian beef cow-calf herds.

    Science.gov (United States)

    Mõtus, Kerli; Reimus, Kaari; Orro, Toomas; Viltrop, Arvo; Emanuelson, Ulf

    2017-04-01

    High on-farm mortality is associated with lower financial return of production and poor animal health and welfare. Understanding the reasons for on-farm mortality and related risk factors allows focus on specific prevention measures. This retrospective cohort study used cattle registry data from the years 2013 and 2014, collected from cattle from all Estonian cow-calf beef herds. The dataset contained 78,605 animal records from 1321 farms in total. Including unassisted deaths and euthanasia (2199 in total) the on-farm mortality rate was 2.14 per 100 animal-years. Across all age groups of both sexes the mortality rate (MR) was highest for bull calves up to three months old (MR=7.78 per 100 animal-years, 95% CI 6.97; 8.68) followed by that for heifer calves (MR=6.21 per 100 animal-years, 95% CI 5.49; 7.02). For female cattle the mortality risk declined after three months of age but increased again among animals over 18 months. The reason for death stated by the farmers was analysed for cattle under animal performance testing. Other/unknown reasons, trauma and accidents, as well as metabolic and digestive disorders, formed the three most commonly reported reasons for death in cattle of all age groups. Weibull proportional hazard models with farm frailty effects were applied in three age categories (calves up to three months, youngstock from three to 18 months and cattle aged over 18 months) to identify factors associated with the risk of mortality. Male sex was associated with increased risk of mortality in cattle up to 18 months of age. No difference between breeds was found for cattle up to 18 months of age. Beef cattle breeds rarely represented or dairy breeds (breed category 'Other') had the highest mortality hazard (HR=1.41, 95% CI 1.11; 1.78) compared to Hereford. The hazard of mortality generally increased with herd size for calves, young stock and older bulls. In female cattle over 18 months of age there was no difference in mortality hazard over herd size

  1. Valores de referência para o teste cardiopulmonar para homens e mulheres sedentários e ativos

    Directory of Open Access Journals (Sweden)

    Artur Haddad Herdy

    2011-01-01

    Full Text Available FUNDAMENTO: Os valores de referência de teste cardiopulmonar (TCP disponíveis no Brasil foram derivados de cicloergômetro, em população sedentária e relativamente pequena. OBJETIVO: Fornecer valores de referência para o TCP em brasileiros de ambos os sexos, sedentários e ativos. MÉTODOS: ENtre 2006 e 2008, 3.992 TCP de indivíduos saudáveis foram selecionados de nosso laboratório. Atletas, fumantes, portadores de qualquer patologia conhecida, usuários de medicação contínua e obesos foram excluídos. VO2 pico foi considerado VO2 máx. Analisamos também VO2 de limiar anaeróbico, ventilação máxima e pulso de oxigênio de acordo com sexo, faixa etária, sedentários e ativos. As faixas etárias foram assim divididas: G1 (15-24 anos, G2 (25-34, G3 (35-44, G4 (45-54, G5 (55-64 e G6 (65-74. RESULTADOS: De acordo com as faixas etárias, os valores médios de VO2 em ml/kg/min com os respectivos desvios-padrão foram: Homem ativo: G1-50,6 ± 7,3; G2-47,4 ± 7,4; G3-45,4 ± 6,8; G4-40,5 ± 6,5; G5-35,3 ± 6,2; G6-30,0 ± 6,1. Mulher ativa: G1-38,9 ± 5,7; G2-38,1 ± 6,6; G3-34,9 ± 5,9; G4-31,1 ± 5,4; G5-28,6 ± 6,1; G6-25,1 ± 4,4. Homem sedentário: G1-47,4 ± 7,9; G2-41,9 ± 7,2; G3-39,0 ± 6,8; G4-35,6 ± 7,7; G5-30,0 ± 6,3; G6-23,1 ± 6,3. Mulher sedentária: G1-35,6 ± 5,7; G2-34,0 ± 4,8; G3-30,0 ± 5,4; G4-27,2 ± 5,0; G5-23,9 ± 4,2; G6-21,2 ± 3,4. CONCLUSÃO: ESte artigo fornece valores de referência de VO2 máx, entre outros parâmetros, no Teste Cardiopulmonar realizados na esteira ergométrica em indivíduos de ambos os sexos, ativos e sedentários.

  2. Reference Materials

    Science.gov (United States)

    Merkus, Henk G.

    Reference materials for measurement of particle size and porosity may be used for calibration or qualification of instruments or for validation of operating procedures or operators. They cover a broad range of materials. On the one hand there are the certified reference materials, for which governmental institutes have certified one or more typical size or porosity values. Then, there is a large group of reference materials from commercial companies. And on the other hand there are typical products in a given line of industry, where size or porosity values come from the analysis laboratory itself or from some round-robin test in a group of industrial laboratories. Their regular application is essential for adequate quality control of particle size and porosity measurement, as required in e.g., ISO 17025 on quality management. In relation to this, some quality requirements for certification are presented.

  3. Determination of reference values for intraocular pressure and Schirmer tear test results in clinically normal domestic donkeys (Equus asinus).

    Science.gov (United States)

    Selk Ghaffari, Masoud; Sabzevari, Amin; Ghamsari, SeyedMehdi; Shad, Hussein

    2017-11-25

    This study was conducted to establish normal reference range for the Schirmer tear test (STT) and intraocular pressure (IOP) in clinically normal donkeys for use in clinical practice. Sixteen adult Ethiopian domestic donkeys were used in this study. Complete ophthalmic examinations were performed without chemical restraint. STT values were evaluated in both eyes of all donkeys using a commercial STT strip. IOP was measured in both eyes with a Tono-Pen Vet (Reichert. USA) without using regional nerve blocks. STT values for all eyes (n=32) were 22.1±6.9 mm/minute with a range of 13-35 mm/minute. Comparison of mean STT values between right (n=16) and left eyes (n=16) showed no differences (P=0.6). Mean ±sd IOP values by applanation tonometry were 17.8±3.7 mmHg (range 13.5-24.5 mmHg). Comparison of mean IOP values between right (n=16) and left eyes (n=16) showed no differences (P=0.7). This initial survey provides means and ranges for IOP and STT values in donkeys. These data will assist veterinary ophthalmologists in more accurate diagnosis and management of ophthalmic diseases in donkeys, including keratoconjunctivitis sicca and glaucoma. © British Veterinary Association (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  4. The Ethics of Ethnographic Attraction: Reflections on the Production of the Finno-Ugric Exhibitions at the Estonian National Museum

    Directory of Open Access Journals (Sweden)

    Art Leete

    2015-06-01

    Full Text Available We intend to explore the production of the Finno-Ugric exhibitions at the Estonian National Museum. Our particular aim is to reveal methodological changes of ethnographic reproduction and to contextualise the museum’s current efforts in ideologically positioning of the permanent exhibition. Through historical–hermeneutical analysis we plan to establish particular museological trends at the Estonian National Museum that have led curators to the current ideological position. The history of the Finno-Ugric displays at the Estonian National Museum and comparative analysis of international museological practices enable us to reveal and interpret different approaches to ethnographic reconstructions. When exhibiting indigenous cultures, one needs to balance ethnographic charisma with the ethics of display. In order to employ the approach of ethical attraction, curators must comprehend indigenous cultural logic while building up ethnographic representations.

  5. Founder mutations characterise the mutation panorama in 200 Swedish index cases referred for Long QT syndrome genetic testing.

    Science.gov (United States)

    Stattin, Eva-Lena; Boström, Ida Maria; Winbo, Annika; Cederquist, Kristina; Jonasson, Jenni; Jonsson, Björn-Anders; Diamant, Ulla-Britt; Jensen, Steen M; Rydberg, Annika; Norberg, Anna

    2012-10-25

    Long QT syndrome (LQTS) is an inherited arrhythmic disorder characterised by prolongation of the QT interval on ECG, presence of syncope and sudden death. The symptoms in LQTS patients are highly variable, and genotype influences the clinical course. This study aims to report the spectrum of LQTS mutations in a Swedish cohort. Between March 2006 and October 2009, two hundred, unrelated index cases were referred to the Department of Clinical Genetics, Umeå University Hospital, Sweden, for LQTS genetic testing. We scanned five of the LQTS-susceptibility genes (KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2) for mutations by DHPLC and/or sequencing. We applied MLPA to detect large deletions or duplications in the KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 genes. Furthermore, the gene RYR2 was screened in 36 selected LQTS genotype-negative patients to detect cases with the clinically overlapping disease catecholaminergic polymorphic ventricular tachycardia (CPVT). In total, a disease-causing mutation was identified in 103 of the 200 (52%) index cases. Of these, altered exon copy numbers in the KCNH2 gene accounted for 2% of the mutations, whereas a RYR2 mutation accounted for 3% of the mutations. The genotype-positive cases stemmed from 64 distinct mutations, of which 28% were novel to this cohort. The majority of the distinct mutations were found in a single case (80%), whereas 20% of the mutations were observed more than once. Two founder mutations, KCNQ1 p.Y111C and KCNQ1 p.R518*, accounted for 25% of the genotype-positive index cases. Genetic cascade screening of 481 relatives to the 103 index cases with an identified mutation revealed 41% mutation carriers who were at risk of cardiac events such as syncope or sudden unexpected death. In this cohort of Swedish index cases with suspected LQTS, a disease-causing mutation was identified in 52% of the referred patients. Copy number variations explained 2% of the mutations and 3 of 36 selected cases (8%) harboured a mutation in the

  6. Founder mutations characterise the mutation panorama in 200 Swedish index cases referred for Long QT syndrome genetic testing

    Directory of Open Access Journals (Sweden)

    Stattin Eva-Lena

    2012-10-01

    Full Text Available Abstract Background Long QT syndrome (LQTS is an inherited arrhythmic disorder characterised by prolongation of the QT interval on ECG, presence of syncope and sudden death. The symptoms in LQTS patients are highly variable, and genotype influences the clinical course. This study aims to report the spectrum of LQTS mutations in a Swedish cohort. Methods Between March 2006 and October 2009, two hundred, unrelated index cases were referred to the Department of Clinical Genetics, Umeå University Hospital, Sweden, for LQTS genetic testing. We scanned five of the LQTS-susceptibility genes (KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 for mutations by DHPLC and/or sequencing. We applied MLPA to detect large deletions or duplications in the KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 genes. Furthermore, the gene RYR2 was screened in 36 selected LQTS genotype-negative patients to detect cases with the clinically overlapping disease catecholaminergic polymorphic ventricular tachycardia (CPVT. Results In total, a disease-causing mutation was identified in 103 of the 200 (52% index cases. Of these, altered exon copy numbers in the KCNH2 gene accounted for 2% of the mutations, whereas a RYR2 mutation accounted for 3% of the mutations. The genotype-positive cases stemmed from 64 distinct mutations, of which 28% were novel to this cohort. The majority of the distinct mutations were found in a single case (80%, whereas 20% of the mutations were observed more than once. Two founder mutations, KCNQ1 p.Y111C and KCNQ1 p.R518*, accounted for 25% of the genotype-positive index cases. Genetic cascade screening of 481 relatives to the 103 index cases with an identified mutation revealed 41% mutation carriers who were at risk of cardiac events such as syncope or sudden unexpected death. Conclusion In this cohort of Swedish index cases with suspected LQTS, a disease-causing mutation was identified in 52% of the referred patients. Copy number variations explained 2% of the

  7. Tests of Nacelle-Propeller Combinations in Various Positions with Reference to Wings V : Clark Y Biplane Cellule - NACA Cowled Nacelle - Tractor Propeller

    Science.gov (United States)

    Valentine, E Floyd

    1935-01-01

    This report is the fifth of a series giving the results obtained from wind tunnel tests on the interference drag and propulsive efficiency of nacelle-propeller-wing combinations. This report gives results of tests of an NACA cowled air-cooled engine nacelle with tractor propeller located in 12 positions with reference to a Clark Y biplane cellule.

  8. A Fresh Look: Testing the Internal/External Frame of Reference Model with Frame-Specific Academic Self-Concepts

    Science.gov (United States)

    Dickhauser, Oliver

    2005-01-01

    Background: Students' self-concepts play an important role in explaining achievement-related behaviour. According to the internal/external frame of reference model (I/E Model), students use two frames of reference to form their mathematical and verbal self-concepts. The model predicts that external comparisons will lead to a positive association,…

  9. The Woman as Wolf (AT 409): Some Interpretations of a Very Estonian Folk Tale

    OpenAIRE

    Merili Metsvahi

    2013-01-01

    The article analyses tale type The Woman as Wolf, which is one of the most popular folk tales in the Estonian Folklore Archives and is represented there both in the form of a fairy tale and in the form of a legend. The vast majority of the versions of The Woman as Wolf were written down in the first part of the 20th century within Estonia and where recorded from Estonians. The article introduces the content of the tale, the origin of the first records from the early 19th century, and the diss...

  10. Identification and testing of reference genes for Sesame gene expression analysis by quantitative real-time PCR.

    Science.gov (United States)

    Wei, Libin; Miao, Hongmei; Zhao, Ruihong; Han, Xiuhua; Zhang, Tide; Zhang, Haiyang

    2013-03-01

    Sesame (Sesamum indicum L.) is an ancient and important oilseed crop. However, few sesame reference genes have been selected for quantitative real-time PCR until now. Screening and validating reference genes is a requisite for gene expression normalization in sesame functional genomics research. In this study, ten candidate reference genes, i.e., SiACT, SiUBQ6, SiTUB, Si18S rRNA, SiEF1α, SiCYP, SiHistone, SiDNAJ, SiAPT and SiGAPDH, were chosen and examined systematically in 32 sesame samples. Three qRT-PCR analysis methods, i.e., geNorm, NormFinder and BestKeeper, were evaluated systematically. Results indicated that all ten candidate reference genes could be used as reference genes in sesame. SiUBQ6 and SiAPT were the optimal reference genes for sesame plant development; SiTUB was suitable for sesame vegetative tissue development, SiDNAJ for pathogen treatment, SiHistone for abiotic stress, SiUBQ6 for bud development and SiACT for seed germination. As for hormone treatment and seed development, SiHistone, SiCYP, SiDNAJ or SiUBQ6, as well as SiACT, SiDNAJ, SiTUB or SiAPT, could be used as reference gene, respectively. To illustrate the suitability of these reference genes, we analyzed the expression variation of three functional sesame genes of SiSS, SiLEA and SiGH in different organs using the optimal qRT-PCR system for the first time. The stability levels of optimal and worst reference genes screened for seed development, anther sterility and plant development were validated in the qRT-PCR normalization. Our results provided a reference gene application guideline for sesame gene expression characterization using qRT-PCR system.

  11. Noor-Eesti rollist eesti kirjandus- ja kultuuriloos. The Role of Young Estonia in Estonian Literary and Cultural History

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    Sirje Olesk

    2012-04-01

    Full Text Available From the beginning of the 20th century on, the activities of the Young Estonia literary movement have had a significant influence on the development of Estonian culture. The group published five Young Estonia albums (1905–1915, the magazine Young Estonia, devoted to science, literature, and the arts (1910– 1911, and the newspaper Vaba Sõna (1914–1916, Free Word. The core of the group was composed of five or six active writers who maintained lively interactions with art and theatre circles. The publications of the Young Estonia Press brought about a revolutionary turn in the design and printing styles of the Estonian-language book. The questions of Young Estonia’s role and meaning have intrigued the Estonian cultural public at different times and in different ways. Young Estonia brought to cultural consciousness liberal views on the interpretation of art as well as an elitist aesthetics. At different times their openness to Europe irritated both the nationalist-minded and internationalists; thus the reception of the Young Estonia movement has been polemical throughout Estonian cultural history. Elapsed time has both opened the way for broader generalizations and, conversely, created a need to reconstruct the cultural context of the beginning of the 20th century. Polemic around Young Estonia was certainly caused by the group as a whole; however, in this article the role of individual members is also highlighted. It is emphasized that the political and aesthetic ideas of the Young Estonians changed synchronously with social conditions, from the 1905 Russian revolution to the world war that ravaged Europe. If the early part of this period saw a more social and nationalist bent to their thinking, then in the years of reaction, positions were taken that were more in keeping with l’art pour l’art. Young Estonia was not a hierarchical organization; rather, its small core group was composed of a narrow circle of friends with various

  12. Long-term complications in Estonian galactosemia patients with a less strict lactose-free diet and metabolic control.

    Science.gov (United States)

    Krabbi, K; Uudelepp, M-L; Joost, K; Zordania, R; Õunap, K

    2011-07-01

    The main aim of our study was to retrospectively evaluate long-term complications and measure urinary galactose and galactitol excretion in classical galactosemia patients in Estonia who have been treated with a less restricted lactose-free diet and metabolic control. Our study group consisted of five classical galactosemia patients aged 7-14 years and diagnosed since 1996 in Estonia. Their diet eliminates lactose present in dairy foods, but we did not restrict the consumption of mature cheeses, fruits and vegetables. All patients had normal growth, except for one patient who was overweight at the last evaluation. In three patients mental and speech development was normal. One patient, number 1, who was diagnosed latest (at 6 weeks of age), had moderate mental retardation, verbal dyspraxia, extrapyramidal signs and bilateral cataracts. In both patients with developmental problems, a brain MRI showed bilateral subcortical changes in the cerebral white matter. Of four females, only patient 4 (p.Q188R homozygote) has premature ovarian insufficiency. Urinary galactose and galactitol content were retrospectively measured using high-performance liquid chromatography and refractive-index detection from urinary samples that were preserved during the years 1996-2009. Galactose ranged from 60 to 600 mmol/mol creatinine (normal=4-6), and galactitol ranged from 70 to 1200 mmol/mol creatinine (normal=2-4), which was 10-100 and 17-300 times higher than the respective reference ranges for galactose and galactitol. We conclude that a less strict lactose-free diet and metabolic control performed in Estonian classical galactosemia patients does not change long-term outcome compared to previously published studies. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Reference values for spirometry and their use in test interpretation: A Position Statement from the Australian and New Zealand Society of Respiratory Science.

    Science.gov (United States)

    Brazzale, Danny; Hall, Graham; Swanney, Maureen P

    2016-10-01

    Traditionally, spirometry testing tended to be confined to the realm of hospital-based laboratories but is now performed in a variety of health care settings. Regardless of the setting in which the test is conducted, the fundamental basis of spirometry is that the test is both performed and interpreted according to the international standards. The purpose of this Australian and New Zealand Society of Respiratory Science (ANZSRS) statement is to provide the background and recommendations for the interpretation of spirometry results in clinical practice. This includes the benchmarking of an individual's results to population reference data, as well as providing the platform for a statistically and conceptually based approach to the interpretation of spirometry results. Given the many limitations of older reference equations, it is imperative that the most up-to-date and relevant reference equations are used for test interpretation. Given this, the ANZSRS recommends the adoption of the Global Lung Function Initiative (GLI) 2012 spirometry reference values throughout Australia and New Zealand. The ANZSRS also recommends that interpretation of spirometry results is based on the lower limit of normal from the reference values and the use of Z-scores where available. © 2016 The Authors. Respirology published by John Wiley & Sons Australia, Ltd on behalf of Asian Pacific Society of Respirology.

  14. Modernizing the Estonian farmhouse, redefining the family, 1880s-1930s.

    Science.gov (United States)

    L'Heureux, Marie-Alice

    2010-01-01

    In the nineteenth century, the transition from a Baltic-German-controlled manor-and-serf economy to individually owned farmsteads transformed all aspects of life including the spatial organization and form of farmhouses in the western provinces of Tsarist Russia. Agricultural experts and social reformers discussed how to update the traditional threshing-room dwelling house (rehielamu) into a healthy dwelling for successful farmers and, after the Estonian War of Independence, for new settlers. Using material culture such as contemporary plans, I show that changing household relationships, in addition to economic and technological factors, helped to transform the ancient rehielamu into a modern dwelling.

  15. Names in Estonian Folk Astronomy - from 'Bird's Way' to 'Milky Way'

    OpenAIRE

    Andres Kuperjanov

    2002-01-01

    This article offers an overview of the different names for the Milky Way and the accompanying beliefs and myths, based on the material in the Estonian Folklore Archives. Astronomically speaking, the Milky Way is a big stellar system – a galaxy. All stellar systems of similar type are called galaxies. Our sun is a fairly common star, lying at the outskirts of the Galaxy. The core of the Galaxy is located in the Sagittarius Constellation where the Milky Way is widest and brightest, but i...

  16. Freedom from theory? An attempt to analyse Sten Karling’s views on (Estonian) art history

    OpenAIRE

    Krista Kodres

    2010-01-01

    This article focuses on a Swedish-born art historian Sten Ingvar Karling who was a professor in the Estonian national University of Tartu from 1933 to 1940. Karling published a great number of texts on local art history that were based on substantial archival inquiry, careful observation and stylistic systematisation of works of art. Karling’s discussions about the nature of art were brief and he hardly stressed the need for theoretical self-reflection. It is, however, obvious that his presen...

  17. Comparative evaluation of bivalent malaria rapid diagnostic tests versus traditional methods in field with special reference to heat stability testing in Central India.

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    Neeru Singh

    Full Text Available BACKGROUND: Malaria presents a diagnostic challenge in areas where both Plasmodium falciparum and P.vivax are co-endemic. Bivalent Rapid Diagnostic tests (RDTs showed promise as diagnostic tools for P.falciparum and P.vivax. To assist national malaria control programme in the selection of RDTs, commercially available seven malaria RDTs were evaluated in terms of their performance with special reference to heat stability. METHODOLOGY/PRINCIPAL FINDINGS: This study was undertaken in four forested districts of central India (July, 2011- March, 2012. All RDTs were tested simultaneously in field along with microscopy as gold standard. These RDTs were stored in their original packing at 25°C before transport to the field or they were stored at 35°C and 45°C upto 100 days for testing the performance of RDTs at high temperature. In all 2841 patients with fever were screened for malaria of which 26% were positive for P.falciparum, and 17% for P.vivax. The highest sensitivity of any RDT for P.falciparum was 98% (95% CI; 95.9-98.8 and lowest sensitivity was 76% (95% CI; 71.7-79.6. For P.vivax highest and lowest sensitivity for any RDT was 80% (95% CI; 94.9 - 83.9 and 20% (95% CI; 15.6-24.5 respectively. Heat stability experiments showed that most RDTs for P.falciparum showed high sensitivity at 45°C upto 90 days. While for P.vivax only two RDTs maintained good sensitivity upto day 90 when compared with RDTs kept at room temperature. Agreement between observers was excellent for positive and negative readings for both P.falciparum and P.vivax (Kappa >0.6-0.9. CONCLUSION: This is first field evaluation of RDTs regarding their temperature stability. Although RDTs are useful as diagnostic tool for P.falciparum and P.vivax even at high temperature, the quality of RDTs should be regulated and monitored more closely.

  18. Building an astrometric reference frame for tests of General Relativity with stellar orbits at the Galactic center with HST and GAIA

    Science.gov (United States)

    Do, Tuan

    2017-08-01

    The short-period star S0-2 will reach its closest approach to the supermassive black hole at the Galactic center in 2018 at a separation of event will offer the first of a series of tests of General Relativity with stellar orbits around a supermassive black hole, an unexplored regime for tests of gravity. While S0-2 has been monitored for over 20 years with high angular resolution measurements from the ground, the astrometric reference frame is currently not stable enough for GR tests. The current reference frame is constructed using observations of 7 radio masers with narrow-field adaptive optics imaging from the ground. While this method provides a reference frame that is stable enough to measure the Keplerian orbits, it does not meet the more stringent requirements needed to measure post-Newtonian effects such as the precession of the periapse of the orbit. The small number of reference stars and the systematic errors associated with using large mosaics to observe these stars limit the accuracy of this method. We propose to construct a new reference frame for tests of gravity with WFC3-IR observations in Cycles 25, 26, & 27. When combined with absolute positions and proper motions from GAIA, these observations will provide the required precision in the reference frame. The WFC3-IR field of view has over 1000 times greater areal coverage than the narrow-field AO observations, providing 3 times the number of absolute reference sources from GAIA. The proposed observations build on a legacy of HST, GAIA, and adaptive optics data to open an era of gravitational science with orbits at the Galactic center.

  19. A proficiency test system to improve performance of milk analysis methods and produce reference values for component calibration samples for infrared milk analysis.

    Science.gov (United States)

    Wojciechowski, Karen L; Melilli, Caterina; Barbano, David M

    2016-08-01

    Our goal was to determine the feasibility of combining proficiency testing, analytical method quality-assurance system, and production of reference samples for calibration of infrared milk analyzers to achieve a more efficient use of resources and reduce costs while maximizing analytical accuracy within and among milk payment-testing laboratories. To achieve this, we developed and demonstrated a multilaboratory combined proficiency testing and analytical method quality-assurance system as an approach to evaluate and improve the analytical performance of methods. A set of modified milks was developed and optimized to serve multiple purposes (i.e., proficiency testing, quality-assurance and method improvement, and to provide reference materials for calibration of secondary testing methods). Over a period of years, the approach has enabled the group of laboratories to document improved analytical performance (i.e., reduced within- and between-laboratory variation) of chemical reference methods used as the primary reference for calibration of high-speed electronic milk-testing equipment. An annual meeting of the laboratory technicians allows for review of results and discussion of each method and provides a forum for communication of experience and techniques that are of value to new analysts in the group. The monthly proficiency testing sample exchanges have the added benefit of producing all-laboratory mean reference values for a set of 14 milks that can be used for calibration, evaluation, and troubleshooting of calibration adjustment issues on infrared milk analyzers. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  20. Idiographic duo-trio tests using a constant-reference based on preference of each consumer: Sample presentation sequence in difference test can be customized for individual consumers to reduce error.

    Science.gov (United States)

    Kim, Min-A; Sim, Hye-Min; Lee, Hye-Seong

    2016-11-01

    As reformulations and processing changes are increasingly needed in the food industry to produce healthier, more sustainable, and cost effective products while maintaining superior quality, reliable measurements of consumers' sensory perception and discrimination are becoming more critical. Consumer discrimination methods using a preferred-reference duo-trio test design have been shown to be effective in improving the discrimination performance by customizing sample presentation sequences. However, this design can add complexity to the discrimination task for some consumers, resulting in more errors in sensory discrimination. The objective of the present study was to investigate the effects of different types of test instructions using the preference-reference duo-trio test design where a paired-preference test is followed by 6 repeated preferred-reference duo-trio tests, in comparison to the analytical method using the balanced-reference duo-trio. Analyses of d' estimates (product-related measure) and probabilistic sensory discriminators in momentary numbers of subjects showing statistical significance (subject-related measure) revealed that only preferred-reference duo-trio test using affective reference-framing, either by providing no information about the reference or information on a previously preferred sample, improved the sensory discrimination more than the analytical method. No decrease in discrimination performance was observed with any type of instruction, confirming that consumers could handle the test methods. These results suggest that when repeated tests are feasible, using the affective discrimination method would be operationally more efficient as well as ecologically more reliable for measuring consumers' sensory discrimination ability. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Proficiency Assessment of Male Volleyball Teams of the 13-15-Year Age Group at Estonian Championships

    Science.gov (United States)

    Stamm, Meelis; Stamm, Raini; Koskel, Sade

    2008-01-01

    Study aim: Assessment of feasibility of using own computer software "Game" at competitions. Material and methods: The data were collected during Estonian championships in 2006 for male volleyball teams of the 13-15-years age group (n = 8). In all games, the performance of both teams was recorded in parallel with two computers. A total of…

  2. Exploring Constructivist Social Learning Practices in Aiding Russian-Speaking Teachers to Learn Estonian: An Action Research Approach

    Science.gov (United States)

    Kiilo, Tatjana; Kutsar, Dagmar

    2012-01-01

    Based on appreciative inquiry and threshold concepts from an intercultural learning perspective, the article makes insights into the constructivist social learning practice of Estonian language learning amongst Russian-speaking teachers in Estonia. The application of educational action research methodology, more specifically that of Bridget…

  3. Radium isotopes in Estonian groundwater: measurements, analytical correlations, population dose and a proposal for a monitoring strategy

    Energy Technology Data Exchange (ETDEWEB)

    Forte, M; Rusconi, R [ARPA Lombardia (Environmental Protection Agency of Lombardia), via Juvara 22, 20129 Milan (Italy); Bagnato, L [Department of Quantitative Methods for Business and Economic Sciences, University of Milan-Bicocca, Piazza dell' Ateneo Nuovo 1, 20126 Milan (Italy); Caldognetto, E; Trotti, F [ARPAV (Environmental Protection Agency of Veneto), via Dominutti 8, 37135 Verona (Italy); Risica, S, E-mail: m.forte@arpalombardia.it [Istituto Superiore di Sanita, Technology and Health Department, viale Regina Elena 299, 00161 Rome (Italy)

    2010-12-01

    In some areas of Estonia, groundwater contains a significant number of natural radionuclides, especially radium isotopes, which may cause radiation protection concern depending on the geological structure of the aquifer. Indeed, the parametric value of 0.1 mSv y{sup -1} for the total indicative dose established by European Directive 98/83/EC, adopted as a limit value in Estonian national legislation, is often exceeded. A Twinning Project between Estonia and Italy was carried out within the framework of the Estonian Transition Facility Programme, sponsored by the European Union. Its aims were to assess the radiological situation of Estonian groundwater and related health consequences. The first step was a study of Estonian aqueducts and the population served by them, and a thorough analysis of the radiological database for drinking water, from which the relevant effective doses for the population were obtained. Particular attention was devoted to doses to children and infants. Correlations between the chemical parameters were investigated, in order to suggest the best possible analytical approach. Lastly, a monitoring strategy, i.e. sampling points and sampling frequencies, was proposed.

  4. The risk of motor neurone disease and multiple sclerosis is different in Estonians and Russians. Data from South Estonia.

    Science.gov (United States)

    Gross-Paju, K; Oöpik, M; Lüüs, S; Kalbe, I; Kaasik, A E

    1999-03-01

    Epidemiological studies were performed in South Estonia to establish the prevalence rate of multiple sclerosis (MS) and motor neurone disease (MND). The case finding method included information from the hospital records of the central hospital in the region-the University Hospital (for MS from 1942 to 1989), from all neurologists in the region, from the Estonian MS Society and Association of Muscular Disorders, and from nursing homes in the region. The prevalence day was 31 December 1989. MND incidence was established for the period of 1986-1995. The results demonstrated high prevalence rates of MS among native Estonians (55.3 per 100 000), somewhat lower prevalence among native-born representatives of other nationalities (43.6 per 100 000) and the lowest prevalence rate of MS among non-Estonian immigrants (26.6 per 100 000). The differences were not statistically significant. The results for MND demonstrated the opposite pattern. The mean annual incidence rate of MND for 10 years was statistically significantly higher among people of other nationalities (2.5 per 100 000) and Russians (2.6 per 100 000), and lower in native-born Estonians (1.1 per 100 000). No differences in health care or clinical picture were established. The reasons for the demonstrated differences in MND incidence remain unclear. Copyright 1999 Lippincott Williams & Wilkins.

  5. Normal weight estonian prepubertal boys show a more cardiovascular-risk-associated adipose tissue distribution than austrian counterparts.

    Science.gov (United States)

    Wallner-Liebmann, Sandra J; Moeller, Reinhard; Horejsi, Renate; Jürimäe, Toivo; Jürimäe, Jaak; Mäestu, Jarek; Purge, Priit; Saar, Meeli; Tafeit, Erwin; Kaimbacher, Petra; Kruschitz, Renate; Weghuber, Daniel; Schnedl, Wolfgang J; Mangge, Harald

    2013-01-01

    Objective. Risk phenotypes for cardiovascular disease (CVD) differ markedly between countries, like the reported high difference in CVD mortality in Austria and Estonia. Hitherto, the goal of this study was to find out risk profiles in body fat distribution yet present in childhood, paving the way for later clinical end points. Methods. he subcutaneous adipose tissue (SAT) distribution patterns in 553 Austrian (A) and Estonian (E) clinically healthy normal weight boys aged 11.1 (±0.8) years were analysed. We applied the patented optical device Lipometer which determines the individual subcutaneous adipose tissue topography (SAT-Top). Results. Total body fat did not differ significantly between E and A boys. A discriminant analysis using all Lipometer data, BMI, and the total body fat (TBF) yielded 84.6% of the boys correctly classified in Estonians and Austrians by 9 body sites. A factor analysis identified the SAT distribution of E as critically similar to male adult patients with coronary heart disease (CHD). Conclusions. We show in normal weight Estonian boys a highly significant decreased fat accumulation on the lower body site compared to age matched Austrian males. This SAT-Top phenotype may play an important role for the increased cardiovascular risk seen in the Estonian population.

  6. The Teacher as the Main Factor Influencing the Welfare of a Child at School: Perspectives from Estonian Families

    Science.gov (United States)

    Tiko, Anne

    2012-01-01

    This article is based on a larger study that examined the expectations and experiences of Estonian parents related to preparation for school, factors influencing the choice of the school, and school troubles and joys. This article focuses on the part of the study concerning the families' expectations for schools and teachers, and on the real…

  7. The Anonymity of Catalan and the Authenticity of Estonian: Two Paths for the Development of Medium-Sized Languages

    Science.gov (United States)

    Soler, Josep

    2013-01-01

    Catalan and Estonian can be considered "medium-sized" languages with some key common features that allow us to analyze the evolution of the two cases comparatively. Firstly, other formerly hegemonic languages (Spanish and Russian, respectively) have historically minoritized them. Secondly, the political equilibrium has now changed in…

  8. University Language Policies and Language Choice among Ph.D. Graduates in Estonia: The (Unbalanced) Interplay between English and Estonian

    Science.gov (United States)

    Soler-Carbonell, Josep

    2014-01-01

    The role of English as a global language and its consequences for the internationalization of higher education are matters that have increasingly drawn the attention of researchers from different fields of language and communication. In this paper, an overview of the situation in Estonia is presented. The Estonian context has not previously been…

  9. Radium isotopes in Estonian groundwater: measurements, analytical correlations, population dose and a proposal for a monitoring strategy.

    Science.gov (United States)

    Forte, M; Bagnato, L; Caldognetto, E; Risica, S; Trotti, F; Rusconi, R

    2010-12-01

    In some areas of Estonia, groundwater contains a significant number of natural radionuclides, especially radium isotopes, which may cause radiation protection concern depending on the geological structure of the aquifer. Indeed, the parametric value of 0.1 mSv y⁻¹ for the total indicative dose established by European Directive 98/83/EC, adopted as a limit value in Estonian national legislation, is often exceeded. A Twinning Project between Estonia and Italy was carried out within the framework of the Estonian Transition Facility Programme, sponsored by the European Union. Its aims were to assess the radiological situation of Estonian groundwater and related health consequences. The first step was a study of Estonian aqueducts and the population served by them, and a thorough analysis of the radiological database for drinking water, from which the relevant effective doses for the population were obtained. Particular attention was devoted to doses to children and infants. Correlations between the chemical parameters were investigated, in order to suggest the best possible analytical approach. Lastly, a monitoring strategy, i.e. sampling points and sampling frequencies, was proposed.

  10. Enhancing Teachers' Curriculum Ownership via Teacher Engagement in State-Based Curriculum-Making: The Estonian Case

    Science.gov (United States)

    Mikser, Rain; Kärner, Anita; Krull, Edgar

    2016-01-01

    Teachers' curriculum ownership is increasingly gaining attention in many countries. It is particularly important that under the conditions of centralized curriculum-making, teachers as final implementers of curricular ideas identify themselves with these ideas. This study investigates Estonian upper secondary school teachers' views on the impact…

  11. Course of Skin Symptoms and Quality of Life in Children Referred for Patch Testing - A Long-term Follow-up Study

    DEFF Research Database (Denmark)

    Simonsen, Anne B; Sommerlund, Mette; Deleuran, Mette

    2014-01-01

    Children are patch tested in the same manner as adults, but little has been done to establish whether positive or negative findings influence the course of skin symptoms. To uncover the course of skin symptoms and the impact of persistent eczema on life quality in paediatric patients referred...... for patch testing, a retrospective questionnaire was sent to children and adolescents referred for patch testing during a 9-year period. Persistent eczema at follow-up was strongly associated to atopic dermatitis, but was not explained by gender, age, contact allergy or time span from patch testing...... to follow-up. Among patients without atopic dermatitis, 23.5% reported to suffer from chronic eczema. Persistent eczema increased the risk of severe impairment of life quality. Our findings indicate a significant risk of childhood eczema becoming chronic and affecting life quality considerably. Patch...

  12. Inverse of Wallin's relation for the effect of strain rate on the ASTM E-1921 reference temperature and its application to reference temperature estimation from Charpy tests

    Energy Technology Data Exchange (ETDEWEB)

    Sreenivasan, P.R., E-mail: sreeprs@yahoo.co.i [Metallurgy and Materials Group, Indira Gandhi Centre for Atomic Research, Kalpakkam 603102 (India)

    2011-01-15

    Research highlights: An inverse relation for the Wallin strain rate equation (WSRE), that is, IWSRE, has been derived for predicting the static reference temperature from dynamic results. Using the IWSRE and some other correlations, a procedure, called IGCAR-procedure, has been developed for conservative estimation of the ASTM E-1921 reference temperature, T{sub 0-est}, from Charpy V-notch ductile-brittle transition tests alone. The T{sub 0-est} by the IGCAR-procedure is termed T{sub q-IGC} to distinguish it from other estimates. {yields}T{sub q-IGC} is neither too conservative nor unacceptably non-conservative. The T{sub q-IGC} along with the conservative Master Curve procedure helps provide assuredly conservative lower-bound fracture toughness curve. - Abstract: An inverse relation to that of Wallin's strain rate equation has been obtained for predicting the static reference temperature from dynamic results. Wallin strain rate equation (WSRE) predicts the reference temperature at faster loading rates (expressed as stress intensity factor - SIF-rates) from room temperature yield strength (RT-YS) and quasi-static reference temperature, T{sub 0}. The inverse WSRE (IWSRE) predicts T{sub 0} from T{sub 0}{sup dy}, that is, T{sub 0} at dynamic loading rates as obtained in impact and other dynamic tests. For this purpose, the same dataset that was used by Wallin for deriving the original WSRE has been used. It has also been found that the dynamic reference temperature obtained by applying the modified Schindler procedure (MSP) to Charpy V-notch (CVN) impact tests, that is, T{sub QSch}{sup dy}, provides a conservative or close estimate of reference temperature corresponding to a loading rate of {approx}10{sup 6} MPa {radical}m s{sup -1}. Then using the T{sub QSch}{sup dy} in the IWSRE along with RT-YS and SIF rate of 10{sup 6} MPa {radical}m s{sup -1}, results in an estimate of quasi-static T{sub 0}, namely, T{sub QMSP-IW}, the subscript indicating use of both the

  13. Tabud ja reeglid. Sissevaateid eesti laagriromaani / Taboos and Rules. Insights into Prison Camp Novels by Estonian Writers

    Directory of Open Access Journals (Sweden)

    Anneli Kõvamees

    2013-12-01

    Full Text Available The article concentrates on Estonian novels depicting Soviet prison camps in the 1940s and 1950s. The goal is to map themes, motifs and characteristics in such novels, concentrating on various taboos and rules in the prison camp environment. For a long time the Soviet prison camp theme was not publicly discussed in Estonia due to political reasons. Texts dealing with prison camps could appear in print only outside the Soviet Union; the way Estonians saw these historical events and hellish experiences were depicted mostly in exile novels. Most notable are the novels by Arved Viirlaid (b. 1922, e.g., Kes tappis Eerik Hormi? (Who Killed Eerik Horm? (1974, Surnud ei loe (The Dead do not Read (1975, Vaim ja ahelad (Mind and Chains (1961. Estonian prison camp novels can be seen as “the literature of testimony”, to use the term by Leona Toker. Dramatic historical events are written down to record the events and to show the inhumane nature of Soviet society. These records of the dramatic past follow certain patterns and create certain self- and hetero-images. A prison camp is a closed territory within a closed territory; prison camps can be seen as small models of Soviet society. Prison camp novels give a detailed view of the environment of the prison camp, its inhabitants and activities. Two central aspects are labour and food; the life of the prisoner whirls around these. The most important thing is to survive, which often leads to moral decline, e.g., stealing, cheating. However, there are lines Estonians do not cross, e.g., cannibalism or homosexual relationships with superiors. Estonians are always depicted as political prisoners (not common criminals and heterosexuals, while Russians are portrayed mainly as criminals and often also as homosexuals. Another important component of the image of the Estonians is their enterprising spirit and ability to manage even under very difficult conditions. Therefore, several oppositions can be identified, e

  14. Behind the Curtains of e-State: Determinants of Online Sexual Harassment among Estonian Children

    Directory of Open Access Journals (Sweden)

    Veronika Kalmus

    2012-11-01

    Full Text Available This article analyses the risk of receiving online sexual messages and experiencing harm among Estonian children. In particular, the paper examines the association between receiving sexual messages and behavioural, psychological and demographic characteristics, and the social mediation of children’s Internet use. Estonian data from EU Kids Online survey are used, involving 780 children aged 11-16. Results demonstrate that 19% of children who use the Internet have received online sexual messages, and 6% have felt disturbed. The probability of receiving sexual messages online is higher for children with risky online and offline behaviour and psychological difficulties. Perceiving online messages as sexually harassing is higher among children with excessive Internet use, lower levels of parental monitoring and higher levels of peer mediation of Internet use. The risk of exposure to harassing sexual messages also differs by age and, more notably, by the minority status. Mediation by parents and teachers plays an insignificant role in reducing teenagers’ risks of receiving sexual messages.

  15. Detection and genetic characterization of relapsing fever spirochete Borrelia miyamotoi in Estonian ticks.

    Directory of Open Access Journals (Sweden)

    Julia Geller

    Full Text Available During the years 2008-2010 I. ricinus and I. persulcatus ticks were collected from 64 sites in mainland Estonia and on the island Saaremaa. Presence of B. miyamotoi was found in 0.9% (23/2622 of ticks. The prevalence in I. persulcatus and I. ricinus ticks differed significantly, 2.7% (15/561 and 0.4% (8/2061, respectively. The highest prevalence rates were in found South-Eastern Estonia in an area of I. persulcatus and I. ricinus sympatry and varied from 1.4% (1/73 to 2.8% (5/178. Co-infections with B. burgdorferi s.l. group spirochetes and tick-borne encephalitis virus were also revealed. Genetic characterization of partial 16S rRNA, p66 and glpQ genes demonstrated that Estonian sequences belong to two types of B. miyamotoi and cluster with sequences from Europe and the European part of Russia, as well as with sequences from Siberia, Asia and Japan, here designated as European and Asian types, respectively. Estonian sequences of the European type were obtained from I. ricinus ticks only, whereas the Asian type of B. miyamotoi was shown for both tick species in the sympatric regions.

  16. Cultural Value Differences, Value Stereotypes, and Diverging Identities in Intergroup Conflicts: The Estonian Example

    Directory of Open Access Journals (Sweden)

    Henrik Dobewall

    2011-07-01

    Full Text Available

    An examination of the relationship between cultural values, value stereotypes and social identities in Estonia, where intergroup conflicts triggered riots in the capital
    Tallinn in April 2007, using data from the European Social Survey on cultural differences and value trends as the background to a survey exploring perceived
    group values and assessed social identities among ethnic Estonians and members of the Russian-speaking minority. The study, conducted in summer 2008, found
    agreement across both ethnic groups about the values of a typical group member, but no accuracy in their attribution. The Estonian students (n = 152 avoided
    Eastern-European identification, while the Russian-speaking students (n = 54 did not want to give up Estonia’s Soviet past. We found that attributed rather than
    self-rated value differences between groups caused the conflicts, whilst diverging identities were found to make value stereotypes more extreme.

  17. Linking a Population Biobank with National Health Registries—The Estonian Experience

    Directory of Open Access Journals (Sweden)

    Liis Leitsalu

    2015-04-01

    Full Text Available The Estonian population-based biobank, with 52,000 participants’ genetic and health data, is the largest epidemiological cohort in the Baltic region. Participants were recruited through a network of medical professionals throughout Estonia (population 1.34 million. Unique legislation as well as a broad consent form give the Estonian Genome Center, a research institute of the University of Tartu, permission to re-contact participants and to retrieve participants’ data from national registries and databases. In addition to two re-contacting projects to update the health data of participants, extensive clinical characterizations have been retrieved from national registries and hospital databases regularly since 2010. Acquiring data from electronic health records and registries has provided a means to update and enhance the database of the Genome Center in a timely manner and at low cost. The resulting database allows a wide spectrum of genomic and epidemiological research to be conducted with the aim of benefitting public health. Future plans include linking the genome center database with the national health information system through X-road and exchanging data in real time, as well as using the genetic data and the technical infrastructure available for piloting personalized medicine in Estonia.

  18. Locally calibrated wave hindcasts in the Estonian coastal sea in 1966–2011

    Directory of Open Access Journals (Sweden)

    Ülo Suursaar

    2013-02-01

    Full Text Available Wave parameters were studied in four differently exposed fetch-limited Estonian coastal sea locations: the Harilaid Peninsula facing W–NW, Letipea N–NE, Matsi SW and Kõiguste SE. Based on high-quality measurements of waves with the bottom-mounted Recording Doppler Current Profiler in 2006–2011, a model for significant wave height was calibrated separately for those locations. Using wind forcing data from Estonian coastal meteorological stations, a set of hindcasts was obtained over the period of 1966–2011. The wave heights showed some quasi-periodic cycles with a high stage in 1980–1995, and probably also from 2007; a prevailing overall decrease in the mean wave height; an increase in high wave events at the windward coasts of West Estonia but a decrease at the northern and southeastern coasts. The spatially contrasting results for differently exposed coasts reflect the corresponding variations in local wind, which are probably caused by changes in large-scale atmospheric pressure patterns above Northern Europe and a poleward shift of cyclones’ trajectories. Although featuring outstanding calibration results, the long-term wave hindcast may be impacted by possible inhomogeneities in the older wind data.

  19. Intestinal lactoflora in Estonian and Norwegian patients with antibiotic associated diarrhea.

    Science.gov (United States)

    Sepp, Epp; Stšepetova, Jelena; Smidt, Imbi; Rätsep, Merle; Kõljalg, Siiri; Lõivukene, Krista; Mändar, Reet; Jaanimäe, Liis; Löhr, Iren H; Natås, Olav B; Naaber, Paul

    2011-12-01

    The disruption of intestinal microbiota is an important risk factor for the development of Clostridium difficile caused antibiotic associated diarrhea (AAD). The role of intestinal lactoflora in protection against C. difficile is unclear. Fecal samples (n = 74) from AAD patients were investigated for C. difficile and lactobacilli by culture and real-time PCR. Lactobacilli were identified by enterobacterial repetitive intergenic consensus PCR (ERIC-PCR) and sequencing of 16S rRNA. In C. difficile negative cases we found somewhat higher counts of intestinal Lactobacilli (5.02 vs. 2.15 CFU log(10)/g; p = 0.053) by culture and more frequently Lactobacillus plantarum (33.3% vs. 9.4%; p = 0.03) as compared with positive ones. Results of total counts of lactobacilli comparing Estonian and Norwegian samples were conflicting by culture and PCR. We found higher colonization of Norwegian AAD patients with L. plantarum (21% vs. 5%, p = 0.053) and Estonians with Lactobacillus gasseri (19% vs. 2%, p = 0.023). Particular lactobacilli (e.g. L. plantarum) may have a role in protection against C. difficile, whereas the meaning of total counts of lactobacilli remains questionable. In different persons and nations, different lactobacilli species may have a protective role against C. difficile. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Mental health and alcohol problems among Estonian cleanup workers 24 years after the Chernobyl accident.

    Science.gov (United States)

    Laidra, Kaia; Rahu, Kaja; Tekkel, Mare; Aluoja, Anu; Leinsalu, Mall

    2015-11-01

    To study the long-term mental health consequences of the 1986 Chernobyl nuclear accident among cleanup workers from Estonia. In 2010, 614 Estonian Chernobyl cleanup workers and 706 geographically and age-matched population-based controls completed a mail survey that included self-rated health, the Posttraumatic Stress Disorder Checklist (PCL), alcohol symptoms (AUDIT), and scales measuring depressive, anxiety, agoraphobia, fatigue, insomnia, and somatization symptoms. Respondents were dichotomized into high (top quartile) and low symptom groups on each measure. Logistic regression analysis detected significant differences between cleanup workers and controls on all measures even after adjustment for ethnicity, education, marital status, and employment status. The strongest difference was found for somatization, with cleanup workers being three times more likely than controls to score in the top quartile (OR = 3.28, 95% CI 2.39-4.52), whereas for alcohol problems the difference was half as large (OR = 1.52, 95% CI 1.16-1.99). Among cleanup workers, arrival at Chernobyl in 1986 (vs. later) was associated with sleep problems, somatization, and symptoms of agoraphobia. The toll of cleanup work was evident 24 years after the Chernobyl accident among Estonian cleanup workers indicating the need for focused mental health interventions.

  1. Linking a population biobank with national health registries-the estonian experience.

    Science.gov (United States)

    Leitsalu, Liis; Alavere, Helene; Tammesoo, Mari-Liis; Leego, Erkki; Metspalu, Andres

    2015-04-16

    The Estonian population-based biobank, with 52,000 participants' genetic and health data, is the largest epidemiological cohort in the Baltic region. Participants were recruited through a network of medical professionals throughout Estonia (population 1.34 million). Unique legislation as well as a broad consent form give the Estonian Genome Center, a research institute of the University of Tartu, permission to re-contact participants and to retrieve participants' data from national registries and databases. In addition to two re-contacting projects to update the health data of participants, extensive clinical characterizations have been retrieved from national registries and hospital databases regularly since 2010. Acquiring data from electronic health records and registries has provided a means to update and enhance the database of the Genome Center in a timely manner and at low cost. The resulting database allows a wide spectrum of genomic and epidemiological research to be conducted with the aim of benefitting public health. Future plans include linking the genome center database with the national health information system through X-road and exchanging data in real time, as well as using the genetic data and the technical infrastructure available for piloting personalized medicine in Estonia.

  2. Groundwater flow model of the Estonian oil shale mining area towards to innovative system

    Energy Technology Data Exchange (ETDEWEB)

    Lind, H. [Tallinn Univ. of Technology (Estonia). Dept. of Mining

    2010-07-01

    Changes in the Estonian groundwater regime are anticipated as oil shale deposits are mined. This paper described a dynamic groundwater flow model used to develop a 3-D groundwater elevation map of the Estonian oil shale mining area. The model was used to provide preliminary estimations of water inflow into the working underground mine areas. The model included 9 closed underground mines, 5 active mine sites, and 2 small open-cast sites. The closed mine sites were filled with water flowing in from the working mine sites. New mines and dewatering programs are planned for the future. A database from observation wells installed within the Keila-Kukruse aquifer was used to extract outputs and determine time steps. The model included 35 pumping stations from the active mine sites. The hydraulic properties for each model layer were defined in 4 model zones. Results of the model showed higher water in-flows from the closed underground sites than earlier predictions had anticipated. 9 refs., 1 tab., 4 figs.

  3. BASIC COLOUR TERMS IN FIVE FINNOUGRIC LANGUAGES AND ESTONIAN SIGN LANGUAGE: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Liivi Hollman

    2012-01-01

    Full Text Available In this paper we compare five Finno-Ugric languages – Estonian,Finnish, Hungarian, Udmurt and Komi-Zyrian – and the Estonian Sign Language (unclassified in different aspects: established basic colour terms, the proportion of basic colour terms and different colour terms in the collected word-corpora, the cognitive salience index values in the list task and the number of dominant colour tiles in the colour naming task. The data was collected, using the field method of Davies and Corbett, from all languages under consideration, providing a distinctive foundation for linguistic comparison. We argue that Finno-Ugric languages seem to possess relatively large colour vocabularies,especially due to their rich variety of word-formation types,e.g. the composition of compound words. All of the languages under consideration have developed to Stage VI or VII, possessing 7 to 11lexicalised basic colour terms. The cognitive salience index helps to distinguish primary and secondary basic colour terms, showing certain comprehensive patterns which are similar to Russian and English.

  4. Freedom from theory? An attempt to analyse Sten Karling’s views on (Estonian art history

    Directory of Open Access Journals (Sweden)

    Krista Kodres

    2010-12-01

    Full Text Available This article focuses on a Swedish-born art historian Sten Ingvar Karling who was a professor in the Estonian national University of Tartu from 1933 to 1940. Karling published a great number of texts on local art history that were based on substantial archival inquiry, careful observation and stylistic systematisation of works of art. Karling’s discussions about the nature of art were brief and he hardly stressed the need for theoretical self-reflection. It is, however, obvious that his presentation and evaluation of artistic material was theory based. His ideas of art as an expression of 'will of art' and 'spirit of the time' and his views about change of styles mostly originated from the Vienna school of art history. At the same time he was a promoter of the concept of Baltic-Nordic artedominium, the construction that confronted the concept of German-dominated artistic past of the Baltic countries. Thus Karling’s logic of the 'construction of (Estonian heritage' was coherent with the aim to strengthen one's own national identity through a new positive art historical narrative that took place intensively in the whole of Europe over the 1920-1930s.

  5. Cardiac stress testing for the diagnosis and management of coronary artery disease: a reference for the primary care physician.

    Science.gov (United States)

    Gajulapalli, Rama Dilip; Aneja, Ashish; Rovner, Aleksandr

    2012-02-01

    Choosing the appropriate stress test is important in the workup of patients with possible myocardial ischemia. This choice often is challenging and sometimes confusing because of the plethora of tests and guidelines available. We present a broad overview of commonly available stress tests and indications to help physicians select the most appropriate stress test for their patients.

  6. Feasibility study for the development of certified reference materials for specific migration testing. Part 1: Initial migrant concentration and specific migration

    NARCIS (Netherlands)

    Stoffers, N.H.; Störmer, A.; Bradley, E.L.; Brandsch, R.; Cooper, I.; Linssen, J.P.H.; Franz, R.

    2004-01-01

    The paper describes a project with the main objective of developing the know how to produce certified reference materials (CRMs) for specific migration testing. Certification parameters discussed are the initial concentration of the migrant in the polymer (C-P,C- 0) and the specific migration into a

  7. Accurate Answers to Reference Queries May Be Provided Less Frequently Than Expected. A Review of: Hernon, P., & McClure, C. (1986. Unobtrusive reference testing: The 55 percent rule. Library Journal, 111(7, 37-41.

    Directory of Open Access Journals (Sweden)

    Eamon C. Tewell

    2010-12-01

    Full Text Available Objective – To determine the number of government documents reference questions that are answered correctly by professional library staff.Design – The authors utilized unobtrusive reference testing: reference queries posed to library personnel who were unaware they were being evaluated. As opposed to other designs that require the researcher’s presence in the setting, unobtrusive testing utilizes proxies to administer test questions to the subjects, reducing the possibility of reporter bias.Setting – Twenty-six public and academic libraries participating in the U.S. Government Printing Office Depository Program located in the Western, Southern, and Midwestern United States. The Federal Depository Program consisted of 1400 libraries at the time of the study. One public and one academic library were chosen for each city.Subjects – Reference and government documents librarians. These two staff types were selected in order to compare the accuracy of each group’s responses to the queries.Methods – A set of 15 predetermined factual and bibliographic questions were developed by the authors and administered to library staff respondents by proxies. Government documents were selected as the foundation for the test questions. In selecting federal depository libraries for their sample the authors could ensure all queries may hypothetically be answered using U.S. Government Printing Office documents, as all of the libraries would hold the resources in question.Graduate students enrolled in the University of Arizona and University of Oklahoma library science programs were trained by the authors to serve as proxies. The proxies posed as library users and administered the set of queries at each selected library. Reference librarians and government documents librarians were tested separately, receiving seven and eight questions respectively at each library visited. Over a four-month period a total of 390 questions were posed and their answers

  8. Vene kirjandus venestusaja eesti koolides. Russian Literature in the Estonian Schools of the Russification Era

    Directory of Open Access Journals (Sweden)

    Ülle Pärli

    2012-04-01

    Full Text Available This article aims to give an overview of literary instruction in schools of the russification era at the beginning of the 20th century in Estonia; this was likewise the curriculum of literary study offered to the generation of educated youth which included the Young Estonians. Based on official documents, archival materials, and memoirs, and through analyses of anthologies, literary histories, and teaching methods in use at the time, we attempt to reconstruct the outlines of literary reading and requirements for students in various types of schools. When, as a result of school reform, Russian became the language of instruction; lessons in Russian became central in the curriculum, alongside the word of God; selections from Russian literature were read in the original language. In the lower grades, teaching was by the so-called ”natural method”, intended to guarantee swift achievement of fluency in ”living Russian language”; this was later replaced by systematic textual analysis, which distinguished between belles lettres and other types of texts. However, the study of literature was always subordinated to the goals of language instruction. In institutions of secondary education, study of Russian literature was separate from language instruction. Indeed, Russian literature was the only literature systematically studied in high schools (though one must keep in mind that not all schools completely followed the official program. Private schools were especially noticeable for their greater freedom, though all of them had to take general curriculum directives into account. Reading of literary texts connected with other languages thus had to remain almost purely illustrative. In view of the above, in the upper grades of elementary school and high school, students obtained a thorough introduction to the Russian classics. According to the official school curriculum, Russian literary history ended with Nikolai Gogol. Attempts were made to ignore

  9. The use of regression analysis in determining reference intervals for low hematocrit and thrombocyte count in multiple electrode aggregometry and platelet function analyzer 100 testing of platelet function.

    Science.gov (United States)

    Kuiper, Gerhardus J A J M; Houben, Rik; Wetzels, Rick J H; Verhezen, Paul W M; Oerle, Rene van; Ten Cate, Hugo; Henskens, Yvonne M C; Lancé, Marcus D

    2017-11-01

    Low platelet counts and hematocrit levels hinder whole blood point-of-care testing of platelet function. Thus far, no reference ranges for MEA (multiple electrode aggregometry) and PFA-100 (platelet function analyzer 100) devices exist for low ranges. Through dilution methods of volunteer whole blood, platelet function at low ranges of platelet count and hematocrit levels was assessed on MEA for four agonists and for PFA-100 in two cartridges. Using (multiple) regression analysis, 95% reference intervals were computed for these low ranges. Low platelet counts affected MEA in a positive correlation (all agonists showed r(2) ≥ 0.75) and PFA-100 in an inverse correlation (closure times were prolonged with lower platelet counts). Lowered hematocrit did not affect MEA testing, except for arachidonic acid activation (ASPI), which showed a weak positive correlation (r(2) = 0.14). Closure time on PFA-100 testing was inversely correlated with hematocrit for both cartridges. Regression analysis revealed different 95% reference intervals in comparison with originally established intervals for both MEA and PFA-100 in low platelet or hematocrit conditions. Multiple regression analysis of ASPI and both tests on the PFA-100 for combined low platelet and hematocrit conditions revealed that only PFA-100 testing should be adjusted for both thrombocytopenia and anemia. 95% reference intervals were calculated using multiple regression analysis. However, coefficients of determination of PFA-100 were poor, and some variance remained unexplained. Thus, in this pilot study using (multiple) regression analysis, we could establish reference intervals of platelet function in anemia and thrombocytopenia conditions on PFA-100 and in thrombocytopenia conditions on MEA.

  10. ASVCP quality assurance guidelines: external quality assessment and comparative testing for reference and in-clinic laboratories.

    Science.gov (United States)

    Camus, Melinda S; Flatland, Bente; Freeman, Kathleen P; Cruz Cardona, Janice A

    2015-12-01

    The purpose of this document is to educate providers of veterinary laboratory diagnostic testing in any setting about comparative testing. These guidelines will define, explain, and illustrate the importance of a multi-faceted laboratory quality management program which includes comparative testing. The guidelines will provide suggestions for implementation of such testing, including which samples should be tested, frequency of testing, and recommendations for result interpretation. Examples and a list of vendors and manufacturers supplying control materials and services to veterinary laboratories are also included. © 2015 American Society for Veterinary Clinical Pathology.

  11. Reference gene selection for quantitative gene expression studies during biological invasions: A test on multiple genes and tissues in a model ascidian Ciona savignyi.

    Science.gov (United States)

    Huang, Xuena; Gao, Yangchun; Jiang, Bei; Zhou, Zunchun; Zhan, Aibin

    2016-01-15

    As invasive species have successfully colonized a wide range of dramatically different local environments, they offer a good opportunity to study interactions between species and rapidly changing environments. Gene expression represents one of the primary and crucial mechanisms for rapid adaptation to local environments. Here, we aim to select reference genes for quantitative gene expression analysis based on quantitative Real-Time PCR (qRT-PCR) for a model invasive ascidian, Ciona savignyi. We analyzed the stability of ten candidate reference genes in three tissues (siphon, pharynx and intestine) under two key environmental stresses (temperature and salinity) in the marine realm based on three programs (geNorm, NormFinder and delta Ct method). Our results demonstrated only minor difference for stability rankings among the three methods. The use of different single reference gene might influence the data interpretation, while multiple reference genes could minimize possible errors. Therefore, reference gene combinations were recommended for different tissues - the optimal reference gene combination for siphon was RPS15 and RPL17 under temperature stress, and RPL17, UBQ and TubA under salinity treatment; for pharynx, TubB, TubA and RPL17 were the most stable genes under temperature stress, while TubB, TubA and UBQ were the best under salinity stress; for intestine, UBQ, RPS15 and RPL17 were the most reliable reference genes under both treatments. Our results suggest that the necessity of selection and test of reference genes for different tissues under varying environmental stresses. The results obtained here are expected to reveal mechanisms of gene expression-mediated invasion success using C. savignyi as a model species. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. The screening of SLC6A8 deficiency among Estonian families with X-linked mental retardation.

    Science.gov (United States)

    Puusepp, H; Kall, K; Salomons, G S; Talvik, I; Männamaa, M; Rein, R; Jakobs, C; Õunap, K

    2010-12-01

    The urinary creatine:creatinine (Cr:Crn) ratio was measured in males from 49 families with a family history compatible with X-linked mental retardation (XLMR) in order to estimate the prevalence of SLC6A8 deficiency in Estonia. We identified 11 boys from 9 families with an increased urinary Cr:Crn ratio (18%). In three related boys, a hemizygous missense mutation (c.1271G>A; p.Gly424Asp) was identified. Their mother was heterozygous for the same mutation. Although many missense mutations have been described, the p.Gly424Asp mutation has not been previously reported. The clinical expression varied widely among affected males of this family. Patients 1 and 3 had relatively mild clinical expression (mild mental retardation (MR) and attention deficit disorder), but patient 2 had all typical clinical signs of SLC6A8 defect such as moderate MR, autistic features, expressive dysphasia and epilepsy. Among our patients, we saw significant problems in speech and language development combined with attention and behavioural difficulties. The number of false-positive biochemical results with increased urinary Cr:Crn ratio was higher (18%) in our study than in previous reports (1.8–10%). We therefore suggest that repeated biochemical testing should be performed before DNA sequencing analysis. Our study suggests that 2% (95% confidence limits: 0.05–11.1%) of this Estonian XLMR panel are due to mutations in the SLC6A8, which is similar to the prevalence reported in other populations. We therefore conclude that creatine transporter deficiency is a relatively common genetic disorder in males with sporadic or familiar MR and diagnostic screening of them should always include screening for SLC6A8 deficiency.

  13. Ultrasonic calibration and certification of V1 and V2 type reference standard blocks for use in Non-Destructive Testing

    OpenAIRE

    Maggi, Luís Eduardo; Silva, Cristiane Evelise Ribeiro da; Alvarenga, André Victor; Costa-Félix, Rodrigo Pereira Barretto da

    2011-01-01

    Ultrasonic Non-Destructive Testing (US-NDT) has many industrial applications,such as flaws detection, welding integrity evaluation and solid material thickness measurement.To evaluate the instrumentation conditions, before a measurement begins, a “calibration” should be carried out with the aid of a reference standard block (RSB). Types V1 (ISO 2400) and V2 (ISO 7963) are the most widely used in US-NDT. Due their characteristics, V1 and V2 RSB can be classified as Reference Material, so that ...

  14. Reference Standards for Cardiorespiratory Fitness Measured With Cardiopulmonary Exercise Testing Using Cycle Ergometry: Data From the Fitness Registry and the Importance of Exercise National Database (FRIEND) Registry.

    Science.gov (United States)

    Kaminsky, Leonard A; Imboden, Mary T; Arena, Ross; Myers, Jonathan

    2017-02-01

    The importance of cardiorespiratory fitness (CRF) is well established. This report provides newly developed standards for CRF reference values derived from cardiopulmonary exercise testing (CPX) using cycle ergometry in the United States. Ten laboratories in the United States experienced in CPX administration with established quality control procedures contributed to the "Fitness Registry and the Importance of Exercise: A National Database" (FRIEND) Registry from April 2014 through May 2016. Data from 4494 maximal (respiratory exchange ratio, ≥1.1) cycle ergometer tests from men and women (20-79 years) from 27 states, without cardiovascular disease, were used to develop these references values. Percentiles of maximum oxygen consumption (VO2max) for men and women were determined for each decade from age 20 years through age 79 years. Comparisons of VO2max were made to reference data established with CPX data from treadmill data in the FRIEND Registry and previously published reports. As expected, there were significant differences between sex and age groups for VO2max (Pstandard differences from treadmill testing reference values. Copyright © 2016 Mayo Foundation for Medical Education and Research. All rights reserved.

  15. Standard practice for fabrication and control of metal, other than aluminum, reference blocks used in ultrasonic testing

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2013-01-01

    1.1 This practice covers a procedure for fabrication and control of metal alloy reference blocks used in ultrasonic examination that have a flat-surface sound entry, are cylindrical in shape, and contain flat-bottom holes (FBH) which may be used for checking the performance of ultrasonic examination instrumentation and search units and for standardization and control of ultrasonic examination of metal alloy products. The reference blocks described are suitable for use with either the direct-contact method or immersion pulse-echo ultrasonic methods. Note 1—Use of flat-surface reference blocks may not be suitable for cylindrical materials (3) . 1.2 While this procedure is basically designed for the fabrication and control of carbon and alloy steel blocks to be used in conjunction with the examination of these materials, the fabrication and control procedures may also be suitable for the preparation of blocks for other types of materials such as nickel-base alloys, certain types of aluminum alloys, and so fo...

  16. Development and characterization of a human antibody reference panel against erythropoietin suitable for the standardization of ESA immunogenicity testing.

    Science.gov (United States)

    Mytych, Daniel T; Barger, Troy E; King, Chadwick; Grauer, Stephanie; Haldankar, Raj; Hsu, Eric; Wu, Michelle Min; Shiwalkar, Mukta; Sanchez, Sergio; Kuck, Andrew; Civoli, Francesca; Sun, Jilin; Swanson, Steven J

    2012-08-31

    Recombinant human erythropoietin (EPO) has been used therapeutically for more than two decades in the treatment of anemia. Although EPO is generally well tolerated, in rare cases, patients have developed anti-EPO antibodies that can negatively impact safety and efficacy. Therefore, the detection of antibodies against EPO is a regulatory requirement during clinical development and post-approval. Although it is a rare phenomenon, antibody-mediated pure red cell aplasia (PRCA) is a serious complication than can result from antibodies that develop and neutralize EPO as well as endogenous erythropoietin. Currently, there are no universally accepted analytical methods to detect the full repertoire of binding and neutralizing anti-EPO antibodies. A number of different methods that differ in terms of antibodies detected and assay sensitivities are used by different manufacturers. There is also a lack of antibody reference reagents, and therefore no consistent basis for detecting and measuring anti-EPO antibodies. Reference reagents, with established ranges, are essential to monitor the safety and efficacy of all erythropoiesis-stimulating agents (ESAs) structurally related to human erythropoietin. This is the first report of the development and characterization of a panel of fully human antibodies against EPO suitable as reference reagents. The characteristics of antibodies within the panel were selected based on the prevalence of non-neutralizing IgG and IgM antibodies in non-PRCA patients and neutralizing IgG antibodies, including IgG1 and IgG4, in antibody-mediated PRCA subjects. The reference panel includes antibodies of high- and low-affinity with binding specificity to neutralizing and non-neutralizing erythropoietin epitopes. The subclass of human antibodies in this reference panel includes an IgG1, IgG2, and IgG4, as well as an IgM isotype. This antibody panel could help select appropriate immunogenicity assays, guide validation, and monitor assay performance

  17. Effect of salt supplementation on the rate of inadequate sweat collection for infants less than 3 months of age referred for the sweat test.

    Science.gov (United States)

    Guglani, Lokesh; Abdulhamid, Ibrahim

    2015-01-01

    Sweat testing in young infants (≤ 3 months) with a positive newborn screen for Cystic Fibrosis (CF) can yield higher rates of inadequate sweat collection. The role of salt supplements in improving sweat collection has not been studied before. All young infants referred to our CF center for sweat testing were randomized to either receive salt supplements {1/8th teaspoon salt (750 mg)} mixed in formula feeds 1 day prior to sweat testing (study group) or no salt supplement (controls). Of the 151 young infants that underwent sweat testing over 18 months, 75 received salt supplements, while 76 did not. A total of 9 (11.8%) infants in the salt supplement group had inadequate sweat collection, as compared to 4 (5.2%) infants in the control group (p = 0.16, Fisher's Exact Test). Oral salt supplementation for young infants prior to sweat testing does not help to reduce the rates of inadequate sweat collection.

  18. A DANREF certified reference plastic for measurement of overall migration into the food simulant olive oil by single sided testing

    DEFF Research Database (Denmark)

    Lund, K. H.; Lillemark, L.; Petersen, Jens Højslev

    2000-01-01

    A reference material for the determination of overall migration from a plastic coextrudate into the fatty food simulant olive oil was produced and certified in an interlaboratory study. The analyses were carried out according to the ENV 1186 standard from the European Committee for Standardization...... (CEN) [1, 2, 3] with exposure of the coextrudate to olive oil for 10 days at 40 degrees C. After an initial preliminary interlaboratory study eight laboratories participated in the certification round, and two different methods were used to obtain single sided exposure of the plastic to the oil...

  19. Trans fatty acid contents in selected dietary fats in the Estonian market.

    Science.gov (United States)

    Meremäe, Kadrin; Roasto, Mati; Kuusik, Sirje; Ots, Meelis; Henno, Merike

    2012-08-01

    In response to public concern, this study assessed the fatty acid (FA) composition of blended spreads, margarines and shortenings in the Estonian retail market in 2011. Special attention was paid to the trans fatty acids (TFA) composition. The changes in these characteristics of selected dietary fats in the market over recent years are also presented. Twenty-six edible fat brands, available in the Estonian retail market in 2011, were purchased and FA compositions were analyzed by chromatography. Saturated fatty acids (SFA) were the dominant group of FAs for all blended spreads (49.6 to 65.8%), and for the majority of shortenings (from 21.1 to 54.6%). Cis monounsaturated fatty acids (MUFA) were the dominant group of FAs for the majority of margarines, ranging from 25.3% to 50.5%. The total TFA for blended spreads varied from 1.18% to 9.08%, for margarines from 0.04% to 34.96% and for shortenings from 0.14% to 39.50%. Octadecenoic (C18:1) isomers were the main TFA found. Compared to 2008/2009, the industrially produced TFA (IP-TFA) content in several of the dietary fat brands was much reduced in 2011. This voluntary reformulation was probably a response to consumer demand associated with a public health campaign directed against IP-TFA in Estonian foods, and were mainly achieved by replacing TFA with SFA C12:0-C16:0. Present paper is directed toward public health related institutions and food industries producing foods with potentially high contents of trans fatty acids (TFA). According to the public concern TFA content in domestic blended spreads has declined significantly over the past 3 y in Estonia. The reduction in the TFA content was achieved by replacing TFA with saturated fatty acids (SFA) (C12:0-C16:0). To shift food composition toward healthier product formulations, mandatory labeling of the sum of IP-TFA and SFA (C12:0-C16:0) was recommended. © 2012 Institute of Food Technologists®

  20. Detection of Candidatus Neoehrlichia mikurensis and Ehrlichia muris in Estonian ticks.

    Science.gov (United States)

    Ivanova, Anna; Geller, Julia; Katargina, Olga; Värv, Kairi; Lundkvist, Åke; Golovljova, Irina

    2017-01-01

    So far neglected bacteria like Candidatud Neoehrlichia mikurensis and Ehrlichia muris-like agents get increased attention in the recent past. Ixodid ticks were demonstrated to harbor both of these pathogens. Estonia is populated by two medically important tick species, I. ricinus and I. persulcatus. In this study the presence of E. muris and Candidatus N. mikurensis in these two tick species was investigated. Tick DNA was analyzed by nested PCR and subsequent sequencing for the presence of 16S rRNA of E. muris and Candidatus N. mikurensis. Positive samples were further confirmed by amplification and sequencing of the partial groESL-operon. The obtained partial groESL sequences were used for construction of a maximum likelihood tree. In total, 776 ticks from 36 collection sites situated in 7 counties on the mainland of Estonia and 2 sites situated in one county on the island Saaremaa were collected. 548 were I. ricinus and 228 were I. persulcatus. Only in 5 counties (11 sites) samples positive for the Anaplasmataceae 16S rRNA gene were found. The percentage of Candidatus N. mikurensis positive ticks varied from 1% to 9.1% at different sites. In Eastern and South-Eastern Estonia, the area where I. ricinus and I. persulcatus are sympatric, no Candidatus N. mikurensis was found. Ticks carrying E. muris were found in three counties, the site-specific percentage of positive ticks varied from 1.2% to 25.6%. This is the first study revealing the presence of Candidatus N. mikurensis and E. muris in Estonian ticks. Candidatus N. mikurensis was found only in the western part of the country exclusively in I. ricinus and the phylogenetic analysis revealed close relatedness of the Estonian sequences to other European Candidatus N. mikurensis strains. E. muris was detected mostly in I. persulcatus and only in one I. ricinus in the sympatric area of both tick species. This is in correspondence with the observation that this pathogen is more often found in I. persulcatus than in I

  1. Re-conceptualizing mother tongue tuition of Estonian abroad as a transnational phenomenon

    Directory of Open Access Journals (Sweden)

    Maarja Siiner

    2017-05-01

    Full Text Available The governmental initiative called the Compatriots Programme, which supports language tuition in Estonian schools and societies abroad, reveals an increased interest in developing intergenerational language transmission in the growing Estonian diaspora. This transnational language political activity signals a new era in language policy, where nation states are increasingly decentralized by migration. The evaluation of the program furthermore reveals that organizing such schools requires a willingness to take language political agency, typically conducted by well-educated and well-integrated resourceful transnational multilingual parents. The present article outlines the results of an ethnographic study of the process of establishing the Estonian School in Copenhagen. This step has demanded a change in the mindset still prevailing in Estonia that language political activities, such as planning language acquisition, are solely the responsibility of the state. Since the prevailing language ideology in Denmark is not favorable towards multilingualism in migrant languages, intergenerational language transmission furthermore presupposes a feeling of ownership of the language and high language self-esteem. "Hargmaise keelepoliitika sünd. Eesti keeleõppe korraldamise võimalikkusest välismaal Taani näitel" Hargmaisus, kasvav väljarändajate arv ja sellega ka eesti keele rääkijate hulk välismaal on jätnud oma jälje eesti keelepoliitikale. Kui varem uuriti peamiselt seda, kuidas eesti keel muukeelses kontekstis muutub, siis viimasel kümnendil on riik asunud aktiivselt toetama eesti keele jätkuvat kasutamist välismaal, rahastades rahvuskaaslaste programmi abil haridusprogramme. Kuid millised faktorid määravad selle, kas uus eestlaste põlvkond oskab ja tahab eesti keelt rääkida? Artikkel hindab etnograafilises ja sotsiolingvistilises võtmes Kopenhaagenis kolm aastat tegutsenud Eesti Kooli ja Lasteklubi näitel, millised on keelekasutust

  2. Diagnosis of pediatric pulmonary tuberculosis with special reference to polymerase chain reaction based nucleic acid amplification test

    Directory of Open Access Journals (Sweden)

    Shreshtha Tiwari

    2015-01-01

    Conclusion/recommendation: The present study reinforces better case detection rate with PCR-based nucleic acid amplification test as compared with microscopy and culture in pediatric pulmonary TB. PCR showed a higher correlation with clinical diagnosis as compared with microscopy and solid culture. Hence, a molecular platform should be the test of choice for detecting PPTB.

  3. Influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza annual report, 2014.

    Science.gov (United States)

    Sullivan, Sheena G; Chow, Michelle K; Barr, Ian G; Kelso, Anne

    2015-12-31

    The WHO Collaborating Centre for Reference and Research on Influenza in Melbourne is part of the World Health Organization's (WHO) Global Influenza Surveillance and Response System. In 2014 the Centre received a total of 5,374 influenza samples from laboratories primarily in the Asia-Pacific region. Viruses were characterised by their antigenic, genetic and antiviral drug resistance properties. Of the viruses successfully analysed 52% were A(H1N1)pdm09 viruses. The majority of these were antigenically and genetically similar to the WHO recommended reference strain for the 2014 Southern Hemisphere influenza vaccine. Results for A(H3N2) and B/Yamagata viruses suggested that circulating viruses of this subtype and lineage, respectively, had undergone antigenic and/or genetic changes, consistent with the decision by WHO to change recommended strains for the 2015 Southern Hemisphere vaccine. A small number of A(H1N1)pdm09 and B/Victoria viruses had highly reduced inhibition to the neuraminidase inhibitors oseltamivir and zanamivir. The Centre also undertook primary isolation of vaccine candidate viruses directly into eggs. A total of 38 viruses were successfully isolated in eggs, of which 1 (B/Phuket/3073/2013) was included in the 2015 Southern Hemisphere influenza vaccine.

  4. Strength and fatigue testing of large size wind turbines rotors. Vol. II: Full size natural vibration and static strength test, a reference case

    Energy Technology Data Exchange (ETDEWEB)

    Arias, F.; Soria, E.

    1996-12-01

    This report shows the methods and procedures selected to define a strength test for large size wind turbine, anyway in particular it application on a 500 kW blade and it results obtained in the test carried out in july of 1995 in Asinel`s test plant (Madrid). Henceforth, this project is designed in an abbreviate form whit the acronym SFAT. (Author)

  5. Single-Patient Molecular Testing with NanoString nCounter Data Using a Reference-Based Strategy for Batch Effect Correction

    OpenAIRE

    Talhouk, Aline; Kommoss, Stefan; Mackenzie, Robertson; Cheung, Martin; Leung, Samuel; Chiu, Derek S.; Kalloger, Steve E.; Huntsman, David G.; Chen, Stephanie; Intermaggio, Maria; Gronwald, Jacek; Chan, Fong C.; Ramus, Susan J.; Steidl, Christian; Scott, David W.

    2016-01-01

    A major weakness in many high-throughput genomic studies is the lack of consideration of a clinical environment where one patient at a time must be evaluated. We examined generalizable and platform-specific sources of variation from NanoString gene expression data on both ovarian cancer and Hodgkin lymphoma patients. A reference-based strategy, applicable to single-patient molecular testing is proposed for batch effect correction. The proposed protocol improved performance in an established H...

  6. Between-Day Reliability and Usefulness of a Fitness Testing Battery in Youth Sport Athletes: Reference Data for Practitioners

    Science.gov (United States)

    Sawczuk, Thomas; Jones, Ben; Scantlebury, Sean; Weakley, Jonathan; Read, Dale; Costello, Nessan; Darrall-Jones, Joshua David; Stokes, Keith; Till, Kevin

    2018-01-01

    This study aimed to evaluate the between-day reliability and usefulness of a fitness testing battery in a group of youth sport athletes. Fifty-nine youth sport athletes (age = 17.3 ± 0.7 years) undertook a fitness testing battery including the isometric mid-thigh pull, counter-movement jump, 5-40 m sprint splits, and the 5-0-5 change of direction…

  7. Sovietisation and the Estonian National Museum during 1940s-1950s

    Directory of Open Access Journals (Sweden)

    Karin Konksi

    2007-12-01

    Full Text Available The article deals with the impacts of the policy of the 1940s-1950s Soviet authority on the Estonian National Museum. The first, introductory part observes the general frameworks of the (ethnographical museums in the Soviet Union, thus providing an overview of the goal of Sovietisation policy – what was the system’s perception of the institution that the ENM was supposed to become. The main part of the article focuses on Sovietisation practice in the ENM: what kind of reorganisation took place within the work of the museum in connection with political changes, whether and how the new norms were adapted to and to what extent they were adopted. The source material used for the treatment of the subject matter comprises, in addition to the ENM’s archive materials, the memories of three ethnologists who worked in the ENM during the observed period.

  8. User Preferences for Improving the Estonian National e-Prescription Service.

    Science.gov (United States)

    Parv, Liisa; Monkman, Helen; Laus, Raimo

    2015-01-01

    National e-Prescription services are becoming more common in Europe. While enhancing communication between levels of health care, few solutions have demonstrated enhanced quality of care and patient safety benefits. The article presents the results of a project to map the user needs the Estonian national e-prescription service. A survey was conducted among primary care physicians (PCPs) to inquire about their needs in the medication management process. The results showed that PCPs lacked a medication management tool to support patient care across different care settings. A mockup for the national service was developed based on the survey results. The medication management tool features a visual presentation of a patient's medication list and includes decision support functions for allergies and potential interactions. This mockup will be used to further investigate the needs of PCPs as well as other care providers in the medication management process.

  9. Probing the perceptual and cognitive underpinnings of braille reading. An Estonian population study.

    Science.gov (United States)

    Veispak, Anneli; Boets, Bart; Männamaa, Mairi; Ghesquière, Pol

    2012-01-01

    Similar to many sighted children who struggle with learning to read, a proportion of blind children have specific difficulties related to reading braille which cannot be easily explained. A lot of research has been conducted to investigate the perceptual and cognitive processes behind (impairments in) print reading. Very few studies, however, have aimed for a deeper insight into the relevant perceptual and cognitive processes involved in braille reading. In the present study we investigate the relations between reading achievement and auditory, speech, phonological and tactile processing in a population of Estonian braille reading children and youngsters and matched sighted print readers. Findings revealed that the sequential nature of braille imposes constant decoding and effective recruitment of phonological skills throughout the reading process. Sighted print readers, on the other hand, seem to switch between the use of phonological and lexical processing modes depending on the familiarity, length and structure of the word. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Mobility of Cd, Pb, Cu, and Cr in some Estonian soil types

    Directory of Open Access Journals (Sweden)

    Irha, Natalya

    2009-09-01

    Full Text Available The sorption capacity of selected heavy metals (Cd, Pb, Cu, Cr to five Estonian soils was evaluated using spiked subsoil samples in laboratory experiments. The experimental sorption data fitted well to the linear Freundlich isotherm. The sorption of metals in subsoil depended on the soil type, e.g., mineral composition. The results indicate that the content of quartz and carbonates is important in affecting the metal sorption capacity of subsoil. On the basis of our data the possibility of penetration in depth and accumulation of mobile metals was evaluated. It was concluded that increase in dissolved Cd and accumulation of other metals in the subsoil of Podzol is expected. The accumulation of Pb could be the main process for soils with a high amount of dolomite.

  11. Grammar School Students’ Opinions on the Art Curriculum: An Estonian, Portuguese and Slovenian Comparative Study

    Directory of Open Access Journals (Sweden)

    Tomaž Zupančič

    2015-09-01

    Full Text Available The article presents the attitude of grammar school students towards the art curriculum. It first provides an overview of the characteristics of contemporary art education, with an emphasis on the postmodern art curriculum and on linking course content with students’ interests. The study is based on the descriptive and causal non-experimental method, with a sample comprising 387 Slovenian, Estonian and Portuguese students. It was established that the students place the highest value on developing creativity, and are less interested in art history content and learning about the basics of the formal art language. They are attracted to contemporary topics, such as graffiti, multicultural art, the use of new media, and digital technologies. The results of the study provide opportunities for future comparative analyses and starting points for updating art curricula.

  12. Whole-word frequency and inflectional paradigm size facilitate Estonian case-inflected noun processing.

    Science.gov (United States)

    Lõo, Kaidi; Järvikivi, Juhani; Baayen, R Harald

    2018-02-15

    Estonian is a morphologically rich Finno-Ugric language with nominal paradigms that have at least 28 different inflected forms but sometimes more than 40. For languages with rich inflection, it has been argued that whole-word frequency, as a diagnostic of whole-word representations, should not be predictive for lexical processing. We report a lexical decision experiment, showing that response latencies decrease both with frequency of the inflected form and its inflectional paradigm size. Inflectional paradigm size was also predictive of semantic categorization, indicating it is a semantic effect, similar to the morphological family size effect. These findings fit well with the evidence for frequency effects of word n-grams in languages with little inflectional morphology, such as English. Apparently, the amount of information on word use in the mental lexicon is substantially larger than was previously thought. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Stroke awareness in two Estonian cities: better knowledge in subjects with advanced age and higher education.

    Science.gov (United States)

    Vibo, Riina; Kõrv, Liisa; Väli, Merle; Tomson, Kadi; Piirsoo, Erika; Schneider, Siim; Kõrv, Janika

    2013-01-01

    This study was undertaken to assess stroke awareness of the Estonian population. Investigators were asked to fill in an original, closed-ended multiple-choice questionnaire about the definition, risk factors, symptoms and behavior at the onset of stroke by randomly selected subjects in public places of the two biggest cities in Estonia (Tallinn and Tartu). The study included 355 persons. Most of the respondents knew that stroke is an acute disease and that one should call the ambulance at the onset of a stroke. Speech disorder and paresis were the best known symptoms, while hypertension was the best known risk factor. There were no differences between the sexes, but advanced age and higher level of education were related to higher awareness. The overall knowledge was better compared to many other studies. Future awareness campaigns should be addressed to younger subjects with lower education. Copyright © 2012 S. Karger AG, Basel.

  14. Fractal and multifractal analysis of complex networks: Estonian network of payments

    Science.gov (United States)

    Rendón de la Torre, Stephanie; Kalda, Jaan; Kitt, Robert; Engelbrecht, Jüri

    2017-12-01

    Complex networks have gained much attention from different areas of knowledge in recent years. Particularly, the structures and dynamics of such systems have attracted considerable interest. Complex networks may have characteristics of multifractality. In this study, we analyze fractal and multifractal properties of a novel network: the large scale economic network of payments of Estonia, where companies are represented by nodes and the payments done between companies are represented by links. We present a fractal scaling analysis and examine the multifractal behavior of this network by using a sandbox algorithm. Our results indicate the existence of multifractality in this network and consequently, the existence of multifractality in the Estonian economy. To the best of our knowledge, this is the first study that analyzes multifractality of a complex network of payments.

  15. Revision of the SNPforID 34-plex forensic ancestry test: Assay enhancements, standard reference sample genotypes and extended population studies.

    Science.gov (United States)

    Fondevila, M; Phillips, C; Santos, C; Freire Aradas, A; Vallone, P M; Butler, J M; Lareu, M V; Carracedo, A

    2013-01-01

    A revision of an established 34 SNP forensic ancestry test has been made by swapping the under-performing rs727811 component SNP with the highly informative rs3827760 that shows a near-fixed East Asian specific allele. We collated SNP variability data for the revised SNP set in 66 reference populations from 1000 Genomes and HGDP-CEPH panels and used this as reference data to analyse four U.S. populations showing a range of admixture patterns. The U.S. Hispanics sample in particular displayed heterogeneous values of co-ancestry between European, Native American and African contributors, likely to reflect in part, the way this disparate group is defined using cultural as well as population genetic parameters. The genotyping of over 700 U.S. population samples also provided the opportunity to thoroughly gauge peak mobility variation and peak height ratios observed from routine use of the single base extension chemistry of the 34-plex test. Finally, the genotyping of the widely used DNA profiling Standard Reference Material samples plus other control DNAs completes the audit of the 34-plex assay to allow forensic practitioners to apply this test more readily in their own laboratories. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  16. Estimation of the crustal motion and noise properties from the time series of Estonian permanent GNSS stations

    Science.gov (United States)

    Kall, Tarmo; Oja, Tõnis; Kollo, Karin; Liibusk, Aive

    2017-04-01

    The Earth's crust is moving continuously due to the processes such as plate tectonics, Earth and ocean tides, glacial isostatic adjustment (GIA), local deformations, atmospheric and hydrological mass variations. Accordingly, the effect of those processes are expected on the measured coordinates of continuously operating GNSS stations. Simultaneously, the imperfections of GNSS such as clock and orbit errors, antenna phase center variations, atmospheric delay, shortcomings due to the site selection and construction, snow accumulation on the antenna radome, etc., generate spurious signals and noise in the observation data. In Estonia and its surrounding, the GIA process is the main cause of the long-term intra-continental deformations and the motion of the permanent GNSS stations. Therefore, the purpose of this contribution was to estimate the long-term velocities and GIA-related signal relied on the coordinate time series of Estonian GNSS stations. For the accurate estimation of GIA-related velocity, known signals were modelled and the properties of spurious signal and noise were analysed. Raw data from the GNSS stations were processed independently with programs GIPSY 6.4 (precise point positioning with fixing ambiguities) and Bernese 5.2 (double difference processing). Accordingly, for every GNSS station two solutions in IGb08 reference frame for the north, east, and up coordinates were computed to form 10 years long time series (from 2007 to 2016). The ITRF2008 velocity model was used to model and subtract the effect of Eurasian plate tectonic motion from data. For the estimation of long-term velocity, the linear trend model complemented with the sinusoidal and step functions (for annual, semi-annual signals and discontinuities in time series) was fitted separately to the north, east, and up coordinate series. Initially, power spectral density was plotted to assess and visualize the noise properties of the residual time series. Additionally, different stochastic

  17. Six consecutive false positive cases from cell-free fetal DNA testing in a single referring centre

    Science.gov (United States)

    Dugo, Nella; Padula, Francesco; Mobili, Luisa; Brizzi, Cristiana; D’Emidio, Laura; Cignini, Pietro; Mesoraca, Alvaro; Bizzoco, Domenico; Cima, Antonella; Giorlandino, Claudio

    2014-01-01

    Introduction recent studies have proposed the introduction of cell-free fetal DNA testing (NIPT-Non Invasive Prenatal Testing) in routine clinical practice emphasizing its high sensibility and specificity. In any case, false positive and false negative findings may result from placental mosaicism, because cell-free fetal DNA originates mainly from placenta. Case we report six cases of women who underwent chorionic villus sampling (CVS) or amniocentesis to confirm the results from NIPT: two Turner syndromes, two Triple X, one Patau syndrome, one Edward syndrome. Results using classic cytogenetic analysis and, also, Array - Comparative Genomic Hybridization (Array CGH) the karyotype of all 5 fetuses was found to be normal. Conclusion results from NIPT must always be confirmed by invasive prenatal diagnosis. It is mandatory to inform the patient that the CVS and amniocentesis still represent the only form of prenatal diagnostic test available. PMID:25332757

  18. Six consecutive false positive cases from cell-free fetal DNA testing in a single referring centre.

    Science.gov (United States)

    Dugo, Nella; Padula, Francesco; Mobili, Luisa; Brizzi, Cristiana; D'Emidio, Laura; Cignini, Pietro; Mesoraca, Alvaro; Bizzoco, Domenico; Cima, Antonella; Giorlandino, Claudio

    2014-01-01

    recent studies have proposed the introduction of cell-free fetal DNA testing (NIPT-Non Invasive Prenatal Testing) in routine clinical practice emphasizing its high sensibility and specificity. In any case, false positive and false negative findings may result from placental mosaicism, because cell-free fetal DNA originates mainly from placenta. WE REPORT SIX CASES OF WOMEN WHO UNDERWENT CHORIONIC VILLUS SAMPLING (CVS) OR AMNIOCENTESIS TO CONFIRM THE RESULTS FROM NIPT: two Turner syndromes, two Triple X, one Patau syndrome, one Edward syndrome. using classic cytogenetic analysis and, also, Array - Comparative Genomic Hybridization (Array CGH) the karyotype of all 5 fetuses was found to be normal. results from NIPT must always be confirmed by invasive prenatal diagnosis. It is mandatory to inform the patient that the CVS and amniocentesis still represent the only form of prenatal diagnostic test available.

  19. Analysis of Properties of Reflectance Reference Targets for Permanent Radiometric Test Sites of High Resolution Airborne Imaging Systems

    Directory of Open Access Journals (Sweden)

    Eero Ahokas

    2010-08-01

    Full Text Available Reliable and optimal exploitation of rapidly developing airborne imaging methods requires geometric and radiometric quality assurance of production systems in operational conditions. Permanent test sites are the most promising approach for cost-efficient performance assessment. Optimal construction of permanent radiometric test sites for high resolution airborne imaging systems is an unresolved issue. The objective of this study was to assess the performance of commercially available gravels and painted and unpainted concrete targets for permanent, open-air radiometric test sites under sub-optimal climate conditions in Southern Finland. The reflectance spectrum and reflectance anisotropy and their stability were characterized during the summer of 2009. The management of reflectance anisotropy and stability were shown to be the key issues for better than 5% reflectance accuracy.

  20. Acute toxicity of metals and reference toxicants to a freshwater ostracod, Cypris subglobosa Sowerby, 1840 and correlation to EC{sub 50} values of other test models

    Energy Technology Data Exchange (ETDEWEB)

    Khangarot, B.S., E-mail: bkhangarot@hotmail.com [Ecotoxicology Division, Indian Institute of Toxicology Research (Formerly: Industrial Toxicology Research Centre), Post Box No. 80, Mahatma Gandhi Marg, Lucknow 226001 (India); Das, Sangita [Ecotoxicology Division, Indian Institute of Toxicology Research (Formerly: Industrial Toxicology Research Centre), Post Box No. 80, Mahatma Gandhi Marg, Lucknow 226001 (India)

    2009-12-30

    The ostracod Cypris subglobosa Sowerby, 1840 static bioassay test on the basis of a 48 h of 50% of immobilization (EC{sub 50}) has been used to measure the toxicity of 36 metals and metalloids and 12 reference toxicants. Among the 36 metals and metalloids, osmium (Os) was found to be the most toxic in the test while boron (B), the least toxic. The EC{sub 50} values of this study revealed positive linear relationship with the established test models of cladoceran (Daphnia magna), sludge worm (Tubifex tubifex), chironomid larvae (Chironomus tentans), protozoan (Tetrahymena pyriformis), fathead minnow (Pimephales promelas), bluegill sunfish (Lepomis macrochirus), and aquatic macrophyte duckweed (Lemna minor). Correlation coefficients (r{sup 2}) for 17 physicochemical properties of metals or metal ions and EC{sub 50}s (as pM) were examined by linear regression analysis. The electronegativity, ionization potential, melting point, solubility product of metal sulfides (pK{sub sp}), softness parameter and some other physicochemical characteristics were significantly correlated with EC{sub 50}s of metals to C. subglobosa. The reproducibility of toxicity test was determined using 12 reference toxicants. The coefficient of variability of the EC{sub 50}s ranged from 6.95% to 55.37% and variability was comparable to that noticed for D. magna and other aquatic test models. The study demonstrated the need to include crustacean ostracods in a battery of biotests to detect the presence of hazardous chemicals in soils, sewage sludges, sediments and aquatic systems.

  1. Exercise capacity and mortality - a follow-up study of 3033 subjects referred to clinical exercise testing.

    Science.gov (United States)

    Korpelainen, Raija; Lämsä, Jenni; Kaikkonen, Kaisu M; Korpelainen, Juha; Laukkanen, Jari; Palatsi, Ilkka; Takala, Timo E; Ikäheimo, Tiina M; Hautala, Arto J

    2016-08-01

    Exercise stress testing is used as a diagnostic and prognostic tool. We determined the prognostic significance of exercise test findings for cardiovascular (CVD) and all-cause mortality in men and women. 3033 subjects underwent a symptom-limited bicycle exercise test. Exercise capacity was defined as the mean of last four minutes of exercise workload. During an average follow-up of 19 years, 186 (11.6%) CVD and 370 (20.6%) all-cause deaths in men and 57 (5.0%) CVD and 155 (12.5%) all-cause deaths in women occurred. Among exercise test variables (workload, ECG, BP, HR), exercise capacity was the strongest predictor of mortality. Low exercise capacity (1st quartile) was associated with a hazard ratio of 4.2 (95% CI: 1.7, 10.8) for CVD and 4.0 (95% CI: 2.5, 6.4) for all-cause mortality compared with high exercise capacity (4th quartile) among men and in women with a 5.4-fold (95% CI: 1.2, 24.0) risk for CVD and 2.3-fold (95% CI: 1.2, 4.3) risk for all-cause mortality, respectively. The relationship between other exercise test variables and mortality was much weaker. Among exercise test variables exercise capacity was the strongest predictor of CVD and all-cause mortality in both genders, and especially CVD deaths in women. Key Messages Exercise capacity was the most powerful predictor of CVD and all-cause mortality in both men and women. Low exercise capacity is a strong predictor of CVD death, especially among women.

  2. Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva

    2008-01-01

    PURPOSE: To compare apparent diffusion coefficient (ADC) measurements from hyperpolarized (HP) helium ((3)He)-magnetic resonance imaging (MRI) with quantitative data from multislice Computed Tomography (CT) (MSCT) of the whole lungs and pulmonary function tests (PFT). MATERIALS AND METHODS: Twenty...... from MSCT. Both mean ADC and MSCT data were compared to PFT, especially percent of predicted diffusing capacity of carbon monoxide (%predicted DLCO), using Pearson's correlation test. RESULTS: Mean ADC and standard deviation values were 0.392+/-0.119 cm(2)/s for the established emphysema group and 0...

  3. Improving search efficiency for systematic reviews of diagnostic test accuracy: an exploratory study to assess the viability of limiting to MEDLINE, EMBASE and reference checking.

    Science.gov (United States)

    Preston, Louise; Carroll, Christopher; Gardois, Paolo; Paisley, Suzy; Kaltenthaler, Eva

    2015-06-26

    Increasing numbers of systematic reviews evaluating the diagnostic test accuracy of technologies are being published. Currently, review teams tend to apply conventional systematic review standards to identify relevant studies for inclusion, for example sensitive searches of multiple bibliographic databases. There has been little evaluation of the efficiency of searching only one or two such databases for this type of review. The aim of this study was to assess the viability of an approach that restricted searches to MEDLINE, EMBASE and the reference lists of included studies. A convenience sample of nine Health Technology Assessment (HTA) systematic reviews of diagnostic test accuracy, with 302 included citations, was analysed to determine the number and proportion of included citations that were indexed in and retrieved from MEDLINE and EMBASE. An assessment was also made of the number and proportion of citations not retrieved from these databases but that could have been identified from the reference lists of included citations. 287/302 (95 %) of the included citations in the nine reviews were indexed across MEDLINE and EMBASE. The reviews' searches of MEDLINE and EMBASE accounted for 85 % of the included citations (256/302). Of the forty-six (15 %) included citations not retrieved by the published searches, 24 (8 %) could be found in the reference lists of included citations. Only 22/302 (7 %) of the included citations were not found by the proposed, more efficient approach. The proposed approach would have accounted for 280/302 (93 %) of included citations in this sample of nine systematic reviews. This exploratory study suggests that there might be a case for restricting searches for systematic reviews of diagnostic test accuracy studies to MEDLINE, EMBASE and the reference lists of included citations. The conduct of such reviews might be rendered more efficient by using this approach.

  4. Reference citation

    National Research Council Canada - National Science Library

    Brkić, Silvija

    2013-01-01

    .... This paper deals with different styles of reference citation. Special emphasis was placed on the Vancouver Style for reference citation in biomedical journals established by the International Committee of Medical Journal Editors...

  5. Performances on Rey Auditory Verbal Learning Test and Rey Complex Figure Test in a healthy, elderly Danish sample--reference data and validity issues

    DEFF Research Database (Denmark)

    Vogel, Asmus; Stokholm, Jette; Jørgensen, Kasper

    2012-01-01

    This study presents Danish data for Rey Auditory Verbal Learning Test (RAVLT) and Rey Complex Figure Test (RCFT) from 100 subjects aged 60-87 years. Education and estimated verbal intelligence (DART score) had a significant impact on the RAVLT trial 1-5 score but not on other RAVLT measures...... to the subjects' copying performance (in separate tables for age and education groups). For all measures on both RAVLT and RCFT wide distributions of scores were found and the impact of this broad score range on the tests' discriminative validity is discussed. RAVLT performances for elderly were similar...

  6. Determination of maximum aerobic velocity by a five minute test with reference to running world records. A theoretical approach.

    Science.gov (United States)

    Chamoux, A; Berthon, P; Laubignat, J F

    1996-01-01

    Field measurement of the maximal aerobic velocity (MAV) is closely linked to effort-duration then to the used protocol. We construct the relationship between running speed and running-duration logarithm from running world records. It appears a noteworthy point at 4.97 minutes, to be suggested as MAV duration point. By agreement, MAV could be measured on field by a five minute test whatever the sport may be.

  7. Phosphorus in Finnish soils in the 1900s with particular reference to the acid ammonium acetate soil test

    Directory of Open Access Journals (Sweden)

    I. SAARELA

    2008-12-01

    Full Text Available Comprehensive research into phosphorus (P in soils and crops began in Finland in the early 1900s. The average amount of total P in the ploughed topsoil layer of mineral soils was about two tonnes per hectare in the 1930s, before the abundant use of fertilisers. The main chemical fractions of P in mineral soils were organic matter, primary apatite and secondary complexes of the hydrous oxides of Al and Fe. Of the smaller amounts of P in light peat soils, as much as 80% was present in stable organic compounds. Field experiments showed that the native P reserves of Finnish soils are poorly available to plants, and that P fertilisers are inefficiently utilised because of the strong fixation of applied phosphate in soils. In evaluations before the late 1950s, all simple chemical tests appeared to be rather unreliable indicators of the supply of P from soils to plants, but later research has shown that the results were impaired by errors implicit in the research materials. Some soil test P values (STPobtained from old samples stored for more than ten years evidently were too high, particularly for organic soils, and many of the soils studied were strongly acidic and therefore biologically less fertile than the chemical P tests indicated. The acid ammonium acetate method (pH 4.65 was introduced in the early 1950s and has since been used in routine soil testing in Finland, not only for P but for all macronutrients except N. In later evaluations of different methods used for estimating the requirement of P fertilisation, the acid ammonium acetate method has proven equal or superior to any other simple chemical method.;

  8. Mutational analysis of COL1A1 and COL1A2 genes among Estonian osteogenesis imperfecta patients.

    Science.gov (United States)

    Zhytnik, Lidiia; Maasalu, Katre; Reimann, Ene; Prans, Ele; Kõks, Sulev; Märtson, Aare

    2017-08-15

    Osteogenesis imperfecta (OI) is a rare bone disorder. In 90% of cases, OI is caused by mutations in the COL1A1/2 genes, which code procollagen α1 and α2 chains. The main aim of the current research was to identify the mutational spectrum of COL1A1/2 genes in Estonian patients. The small population size of Estonia provides a unique chance to explore the collagen I mutational profile of 100% of OI families in the country. We performed mutational analysis of peripheral blood gDNA of 30 unrelated Estonian OI patients using Sanger sequencing of COL1A1 and COL1A2 genes, including all intron-exon junctions and 5'UTR and 3'UTR regions, to identify causative OI mutations. We identified COL1A1/2 mutations in 86.67% of patients (26/30). 76.92% of discovered mutations were located in the COL1A1 (n = 20) and 23.08% in the COL1A2 (n = 6) gene. Half of the COL1A1/2 mutations appeared to be novel. The percentage of quantitative COL1A1/2 mutations was 69.23%. Glycine substitution with serine was the most prevalent among missense mutations. All qualitative mutations were situated in the chain domain of pro-α1/2 chains. Our study shows that among the Estonian OI population, the range of collagen I mutations is quite high, which agrees with other described OI cohorts of Northern Europe. The Estonian OI cohort differs due to the high number of quantitative variants and simple missense variants, which are mostly Gly to Ser substitutions and do not extend the chain domain of COL1A1/2 products.

  9. Toxicity testing with the benthic diatom Navicula libonensis (Schoeman 1970): procedure optimisation and assessment of the species sensitivity to reference chemicals.

    Science.gov (United States)

    Vidal, Tânia; Pereira, Joana Luísa; Abrantes, Nelson; Almeida, Salomé F P; Soares, Amadeu M V M; Gonçalves, Fernando

    2014-07-01

    Periphytic communities are good indicators of river quality due to their general sensitivity to several pollutants. The primary objective of this study was to develop and optimize an ecotoxicological testing methodology using the freshwater benthic diatom Navicula libonensis. This species was selected due to its ubiquity and suitability for use under laboratory conditions. In the most suitable test medium (Chu10) the diatom demonstrated comparable sensitivity to potassium dichromate and 3,5-dichlorophenol using growth rate as the reference parameter, with median effect concentrations (ErC50) in the same order of magnitude (0.119 and 0.799 mg L(-1)) respectively. Yield-based estimates did not confirm this pattern and potassium dichromate was one order of magnitude more toxic than 3,5-dichlorophenol. The sensitivity of N. libonensis to the reference chemicals was higher than that published in the literature for several standard planktonic microalgae. This advantage, as well as the ability to grow the species in the laboratory, supports further efforts towards the standardisation of a toxicity testing protocol. In addition, the functional role of benthic diatoms in lotic ecosystems justifies their inclusion in risk assessment test batteries to better cover an environmental compartment that has so far been neglected.

  10. Comparison of a flow assay for brucellosis antibodies with the reference cELISA test in West African Bos indicus.

    Directory of Open Access Journals (Sweden)

    Barend M deC Bronsvoort

    Full Text Available Brucellosis is considered by the Food and Agricultural Organisation and the World Health Organisation as one of the most widespread zoonoses in the world. It is a major veterinary public health challenge as animals are almost exclusively the source of infection for people. It is often undiagnosed in both human patients and the animal sources and it is widely acknowledged that the epidemiology of brucellosis in humans and animals is poorly understood, particularly in sub-Saharan Africa. It is therefore important to develop better diagnostic tools in order to improve our understanding of the epidemiology and also for use in the field for disease control and eradication. As with any new diagnostic test, it is essential that it is validated in as many populations as possible in order to characterise its performance and improve the interpretation of its results. This paper describes a comparison between a new lateral flow assasy (LFA for bovine brucellosis and the widely used cELISA in a no gold standard analysis to estimate test performance in this West African cattle population. A Bayesian formulation of the Hui-Walter latent class model incorporated previous studies' data on sensitivity and specificity of the cELISA. The results indicate that the new LFA is very sensitive (approximately 87% and highly specific (approximately 97%. The analysis also suggests that the current cut-off of the cELSIA may not be optimal for this cattle population but alternative cut-offs did not significantly change the estimates of the LFA. This study demonstrates the potential usefulness of this simple to use test in field based surveillance and control which could be easily adopted for use in developing countries with only basic laboratory facilities.

  11. Comparison of a Flow Assay for Brucellosis Antibodies with the Reference cELISA Test in West African Bos indicus

    Science.gov (United States)

    Bronsvoort, Barend M. deC.; Koterwas, Bronwyn; Land, Fiona; Handel, Ian G.; Tucker, James; Morgan, Kenton L.; Tanya, Vincent N.; Abdoel, Theresia H.; Smits, Henk L.

    2009-01-01

    Brucellosis is considered by the Food and Agricultural Organisation and the World Health Organisation as one of the most widespread zoonoses in the world. It is a major veterinary public health challenge as animals are almost exclusively the source of infection for people. It is often undiagnosed in both human patients and the animal sources and it is widely acknowledged that the epidemiology of brucellosis in humans and animals is poorly understood, particularly in sub-Saharan Africa. It is therefore important to develop better diagnostic tools in order to improve our understanding of the epidemiology and also for use in the field for disease control and eradication. As with any new diagnostic test, it is essential that it is validated in as many populations as possible in order to characterise its performance and improve the interpretation of its results. This paper describes a comparison between a new lateral flow assasy (LFA) for bovine brucellosis and the widely used cELISA in a no gold standard analysis to estimate test performance in this West African cattle population. A Bayesian formulation of the Hui-Walter latent class model incorporated previous studies' data on sensitivity and specificity of the cELISA. The results indicate that the new LFA is very sensitive (∼87%) and highly specific (∼97%). The analysis also suggests that the current cut-off of the cELSIA may not be optimal for this cattle population but alternative cut-offs did not significantly change the estimates of the LFA. This study demonstrates the potential usefulness of this simple to use test in field based surveillance and control which could be easily adopted for use in developing countries with only basic laboratory facilities. PMID:19381332

  12. Equações de referência para os testes de caminhada de campo em adultos saudáveis Reference equations for the performance of healthy adults on field walking tests

    Directory of Open Access Journals (Sweden)

    Victor Zuniga Dourado

    2011-10-01

    Full Text Available OBJETIVO: Desenvolver equações de regressão para a previsão das distâncias caminhadas nos testes de caminhada de seis minutos e incremental shuttle walk test (DTC6 e ISWD baseadas em atributos demográficos, antropométricos e força de preensão manual. MÉTODOS: Avaliamos a DTC6 e ISWD em 98 adultos saudáveis. Estatura, peso e força de preensão manual foram também avaliados. Equações ajustadas para idade, gênero, estatura e peso e equações, incluindo também a força de preensão manual, foram desenvolvidas dos dados de 90 participantes (40 homens; 60 ± 9 anos. Aplicamos prospectivamente as equações em 8 participantes (4 homens; 59 ± 10 anos randomicamente selecionados da amostra inicial. RESULTADOS: Idade, gênero, altura e peso explicaram coletivamente 54,5% e 64,9% da variância da DTC6 e ISWD, respectivamente, ao passo que idade, altura, peso e força de preensão manual explicaram coletivamente 54,4% e 69.0% da variância da DTC6 e ISWD, respectivamente. A diferença entre a DTC6 prospectivamente avaliada e prevista não foi significativa usando equações com e sem força de preensão manual (14 ± 57 m vs. 13 ± 67 m. Resultados semelhantes foram observados para a ISWD (25 ± 104 m vs. 25 ± 93 m. CONCLUSÕES: A força de preensão manual é um determinante para DTC6 e ISWD; entretanto, não foi capaz de aumentar o poder das equações ajustadas por variáveis demográficas e antropométricas. A validade de nossos modelos incluindo a força de preensão manual deve ser avaliada em pacientes com disfunção muscular esquelética.OBJECTIVE: To develop regression equations for predicting six-minute and incremental shuttle walk distances (6MWD and ISWD, respectively, based on demographic characteristics, anthropometric variables, and grip strength. METHODS: We evaluated 6MWD and ISWD in 98 healthy adults. Height, weight, and grip strength were also assessed. Using data from 90 of the participants (40 males; 60 ± 9 years

  13. Equações de referência para o teste de caminhada de seis minutos em indivíduos saudáveis Ecuaciones de referencia para el test de caminata de seis minutos en individuos sanos Reference equations for the 6-minute walk test in healthy individuals

    Directory of Open Access Journals (Sweden)

    Victor Zuniga Dourado

    2011-06-01

    Full Text Available O teste de caminhada de 6 minutos (TC6 tem sido amplamente utilizado no ambiente clínico. Algumas equações de referência para a previsão da distância percorrida no teste (DTC6 estão disponíveis na literatura. Esta revisão teve como objetivo discutir criticamente os achados da literatura, publicados em português e em inglês (LILACS, SCIELO, MEDLINE e PUBMED, que avaliaram os valores normais e elaboraram equações de referência para a previsão da DTC6 em indivíduos saudáveis, comparando-os aos resultados recentemente obtidos em indivíduos brasileiros. Idade, gênero, peso, estatura e índice de massa corporal foram os atributos demográficos e antropométricos mais frequentemente correlacionados com a DTC6. As equações resultantes desses atributos foram capazes de explicar entre 25 e 66% da variabilidade total da DTC6. Lamentavelmente, as equações estrangeiras não são adequadas para a população brasileira. Mesmo quando o teste é realizado sob padronização rigorosa, a diferença de performance no TC6 entre estrangeiros e brasileiros permanece, indicando a necessidade dos valores de referências específicos para cada população e/ou etnia. Nesse sentido, as equações desenvolvidas recentemente no Brasil são, provavelmente, as mais apropriadas para interpretar a performance de caminhada dos nossos compatriotas com doenças crônicas que afetam a capacidade para realizar exercícios. Estudos futuros com amostras substancialmente maiores (e.g. multicêntricos e com técnica de amostragem randomizada são necessários para que os valores de referência da DTC6 sejam mais representativos.El test de caminata de 6 minutos (TC6 ha sido ampliamente utilizado en el ambiente clínico. Algunas ecuaciones de referencia para la previsión de la distancia recorrida en el test (DTC6 están disponibles en la literatura. Esta revisión tuvo como objetivo discutir críticamente los hallazgos de la literatura, publicados en portugués y

  14. Scanning Optical Head with Nontilted Reference Beam: Assuring Nanoradian Accuracy for a New Generation Surface Profiler in the Large-Slope Testing Range

    Directory of Open Access Journals (Sweden)

    Shinan Qian

    2011-01-01

    Full Text Available Nanoradian Surface Profilers (NSPs are required for state-of-the-art synchrotron radiation optics and high-precision optical measurements. Nano-radian accuracy must be maintained in the large-angle test range. However, the beams' notable lateral motions during tests of most operating profilers, combined with the insufficiencies of their optical components, generate significant errors of ∼1 μrad rms in the measurements. The solution to nano-radian accuracy for the new generation of surface profilers in this range is to apply a scanning optical head, combined with nontilted reference beam. I describe here my comparison of different scan modes and discuss some test results.

  15. [Possibilities of testing the biological acceptability of composite filling materials, with special reference to the microscopic test for pulp vitality. Review of the literature].

    Science.gov (United States)

    Nyárasdy, I

    1990-08-01

    The main problem of microscopically observing the living pulpa consists in that it lies embedded into hard tissue. The haemodynamics of the pulpa may be defined by studying the physical parameters by examining the characteristics of blood flow and by the factors determining them. By comparison with other tissues little work is dealing with regulating the blood flow. The vital microscopic model of the rat incisor pulpa was first employed by Gängler to testing dental filling materials. The results thereof well complete the findings of standardized tests. On basis of the foregoing the sublining in case of clinical employment of composite filling materials is unconditionally suggested.

  16. Comparison of two rapid influenza A/B test kits with reference methods showing high specificity and sensitivity for influenza A infection.

    Science.gov (United States)

    Booth, Susanne; Baleriola, Cristina; Rawlinson, William D

    2006-05-01

    The rapid detection of influenza viruses is important for forming preventative strategies, directing initiation of anti-viral therapy, detecting potential avian influenza viruses, and excluding influenza-like pathogens, such as SARS. The ImmunoCard STAT! Flu A and B Plus test (Meridian Bioscience, Cincinnati, OH) is a new point of care (POC) test utilizing influenza-specific monoclonal antibodies for rapid diagnosis. The performance of this assay was compared to the established POC Binax NowFlu A and NowFlu B test, and the reference diagnostic standards of viral culture, indirect immunofluorescence (IFA), and RT-PCR where appropriate. Testing of nasopharyngeal aspirates (NPA) from children, throat swabs, and nasal swabs from adults indicated ImmunoCard STAT! specificity of 98% and 100% for influenza A and B, respectively in 224 specimens. The Binax test showed specificity of 99% and 100%, respectively for influenza A and B. Sensitivity results were identical for both rapid detection kits (80% and 47% for Flu A and B, respectively). Overall results were very similar for both testing devices with the advantage of ImmunoCard STAT! Flu A and B Plus test detecting influenza A and B with sharp and easy to read results. Copyright 2006 Wiley-Liss, Inc.

  17. Submicroscopic chromosome imbalance in patients with developmental delay and/or dysmorphism referred specifically for Fragile X testing and karyotype analysis

    Directory of Open Access Journals (Sweden)

    Docherty Zoe

    2008-03-01

    Full Text Available Abstract Background Microdeletion syndromes are generally identified because they usually give rise to specific phenotypic features; many of these deletions are mediated by duplicons or LCRs. The phenotypes associated with subtelomeric deletions are also becoming recognised. However, reciprocal duplication events at these loci are less easily recognised and identified, as they may give rise to milder phenotypic features, and the individuals carrying them may not therefore be referred for appropriate testing. 403 patients with developmental delay and/or dysmorphism, referred to our Genetics Centre for karyotyping and Fragile X expansion testing, were assessed for chromosome imbalance by Multiplex Ligation-dependent Probe Amplification (MLPA. Two MLPA kits were used, one containing probes for the subtelomere regions, and one containing probes for common microdeletion loci. 321 patients were tested with both kits, 75 with the subtelomere kit alone, and 7 with the microdeletion kit alone. Results 32 patients had abnormal results; the overall abnormality detection rate was 2.5% for karyotype analysis and 7.2% for MLPA testing; 5.5% of subtelomere tests and 2.1% of microdeletion tests gave abnormal results. Of the abnormal MLPA results, 5 were in cases with cytogenetically visible abnormalities; of the remaining, submicroscopic, changes, 3 results were established as de novo and 8 were inherited; parental samples were not available for the remaining cases. None of the patients was found to have a Fragile X expansion. Conclusion Karyotype analysis in combination with MLPA assays for subtelomeres and microdeletion loci may be recommended for this patient group.

  18. Targeted Next Generation Sequencing Approach in Patients Referred for Silver-Russell Syndrome Testing Increases the Mutation Detection Rate and Provides Decisive Information for Clinical Management.

    Science.gov (United States)

    Meyer, Robert; Soellner, Lukas; Begemann, Matthias; Dicks, Severin; Fekete, György; Rahner, Nils; Zerres, Klaus; Elbracht, Miriam; Eggermann, Thomas

    2017-08-01

    To investigate the contribution of differential diagnoses to the mutation spectrum of patients referred for Silver-Russell syndrome (SRS) testing. Forty-seven patients referred for molecular testing for SRS were examined after exclusion of one of the SRS-associated alterations. After clinical classification, a targeted next generation sequencing approach comprising 25 genes associated with other diagnoses or postulated as SRS candidate genes was performed. By applying the Netchine-Harbinson clinical scoring system, indication for molecular testing for SRS was confirmed in 15 out of 47 patients. In 4 out of these 15 patients, disease-causing variants were found in genes associated with other diagnoses. These patients carried mutations associated with Bloom syndrome, Mulibrey nanism, KBG syndrome, or IGF1R-associated short stature. We could not detect any pathogenic mutation in patients with a negative clinical score. Some of the differential diagnoses detected in the cohort presented here have a major impact on clinical management. Therefore, we emphasize that the molecular defects associated with these clinical pictures should be excluded before the clinical diagnosis "SRS" is made. Finally, we could show that a broad molecular approach including the differential diagnoses of SRS increases the detection rate. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Results of Drug addiction Test and its Correlation With the Demographic Specifications Among People Referred to Yazd Addiction Diagnostic Laboratory Centre

    Directory of Open Access Journals (Sweden)

    2014-05-01

    Full Text Available Abstract Introduction: Addiction changes people from positive, active and healthy beings to consuming and negative patients. This study was carried out with the aim of determining the prevalence of the abuse of epioid substances among people referring to Yazd Addiction Diagnosis Laboratory using Rapid Test and Chromatography. Methods: In this descriptive cross-sectional study, all people who attended Yazd Addiction Diagnosis Laboratory for any reason, that is, marriage, employment or obtaining job license between 1386 and 1388, were examined. Totally, 2790 individuals were selected randomly. First, their demographic information was entered in the questionnaire. Then, urine samples were collected at the presence of a laboratory technician and tested using Ennissan Strip Rapid Test if the result was positive, the rest of the sample was tested with Chromatography. Results: Totally, 2790 individuals were surveyed in this study. The mean age of the participants was 25.9±7.2 years. About 62.9% were male and the rest were female. In addition, the reason for taking the test was marriage in 73.2%, employment in 15.5%, obtaining job license in 3.3% and other reasons for others. The prevalence of the abuse of opioid substances was 5.3% (95% CI 4.5% - 6.1%. Conclusions: Many test takers are aware of the fact that the result of the drug test becomes negative after three days of withdrawal, which might be the reason for the low prevalence of addiction in this study. However, prenuptial testing for addiction is quite prudent and necessary. Moreover, calculation of OR showed a male to female ratio of 15 to 1 for opioid abuse which was significant. Higher age, lower education level, labor work and working freelance, smoking and history of addiction in family were other risk factors for opioid substance abuse. Keywords: Addiction test, Addiction prevalence rate, Rapid test, Yazd

  20. Direct Comparison of the Histidine-rich Protein-2 Enzyme-linked Immunosorbent Assay (HRP-2 ELISA) and Malaria SYBR Green I Fluorescence (MSF) Drug Sensitivity Tests in Plasmodium falciparum Reference Clones and Fresh ex vivo Field Isolates from Cambodia

    Science.gov (United States)

    2013-07-12

    fluorescence (MSF) drug sensitivity tests in Plasmodium falciparum reference clones and fresh ex vivo field isolates from Cambodia Suwanna...assay (HRP-2 ELISA) and malaria SYBR Green I fluorescence (MSF) drug sensitivity tests were directly compared using Plasmodium falciparum reference... Plasmodium falciparum reference clones and fresh ex vivo field isolates from Cambodia Suwanna Chaorattanakawee 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c

  1. With or without articles? A comparison of article-like determiners in Estonian and Finnish

    Directory of Open Access Journals (Sweden)

    Helen Hint

    2017-10-01

    Full Text Available In this paper, we compare the use and functions of definite and indefinite article-like determiners in Estonian and Finnish. Our main aim is to explore whether the factors that explain the choice of particular determiner forms are similar in Estonian and Finnish. We use a picture-sequence based elicitation experiment to collect spoken narratives from adult native speakers of Estonian and Finnish, and apply non-parametric tree and forest models to analyze the data. Our findings indicate that number of mention and animacy are important predictor variables in both languages, but their exact effect is divergent. We also find that in Finnish, case of the determiner NP proves to be an important factor, while in Estonian, syntactic role of the NP explains some aspects of determiner form choice. Nevertheless, the overall usage frequency of determiners is modest in the Estonian and Finnish data, and the process of grammaticalizing articles is only in initial stages in both languages. *** Artikliga, artiklita? Eesti ja soome keele artiklilaadsete määratlejate võrdlus Siinses uurimuses analüüsime võrdlevalt artiklilaadseid definiitseid ja indefiniitseid määratlejaid eesti ja soome keeles. Eelkõige kõrvutame eesti keele definiitset määratlejat see ja soome keele definiitseid määratlejaid se ja tämä ning eesti ja soome indefiniitset määratlejat üks/yks(i. Samuti vaatleme eesti keele possessiivpronoomeni oma ning soome 3sg possessiivsufiksi (-nsa/-nsä, -Vn referentsiaalseid omadusi. Uurimuse põhieesmärgiks on selgitada, millised on peamised määratlejate kasutust mõjutavad keelelised faktorid eesti ja soome keeles ning kas need faktorid on keeliti sarnased või erinevad. Ühtlasi otsime vastust küsimusele, kas eesti ja soome keeles on põhjust rääkida määratlejate grammatisatsioonist artikliteks. Uuritav keelematerjal pärineb pildiseeria põhjal kogutud suulistest narratiividest. Uurimuses osales 20 eesti ja 20 soome keele

  2. Relationship of the Kaufman Brief Intelligence Test-Second Edition and the Wechsler Abbreviated Scale of Intelligence in children referred for ADHD.

    Science.gov (United States)

    Raggio, Donald J; Scattone, Dorothy; May, Warren

    2010-04-01

    This study examines the relationship between the Wechsler Abbreviated Scale of Intelligence (WASI) and the Kaufman Brief Intelligence Test-Second Edition (KBIT-2). Increasingly, psychologists are using brief measures of intelligence, but scant information exists regarding their clinical utility in various populations. 44 children referred for evaluation of ADHD were administered the KBIT-2 and WASI in counterbalanced order. Results of this study indicated the WASI to be a more stable measure of ADHD children's intelligence, that the KBIT-2 Vocabulary scores were significantly lower than the WASI Verbal score, and that there was significant variability within participants.

  3. Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva

    2008-01-01

    -seven subjects, 22 with established emphysema and 5 with preclinical emphysema defined by PFT criteria, were examined with HP (3)He-MRI and MSCT. Mean age was 55 (+/-12) years, 18 female and 9 male. Mean ADC from (3)He-MRI was compared with emphysema index (EI), 15th percentile and mean lung density (MLD) values...... from MSCT. Both mean ADC and MSCT data were compared to PFT, especially percent of predicted diffusing capacity of carbon monoxide (%predicted DLCO), using Pearson's correlation test. RESULTS: Mean ADC and standard deviation values were 0.392+/-0.119 cm(2)/s for the established emphysema group and 0.......216+/-0.046 for the pre-clinical emphysema group. MSCT values for the established emphysema group and pre-clinical emphysema group were: EI (%) 11+/-12 and 0.4+/-0.6, respectively; 15th percentile (Hounsfield Units (HU)), -956+/-25 and -933+/-13, respectively and MLD (HU) -877+/-20 and -863+/-15, respectively...

  4. Grupuskulaarne identiteediloome paremäärmuslaste võrgusuhtluses / The Formation of Groupuscular Identity in the Web Communication of the Estonian Extreme Right

    Directory of Open Access Journals (Sweden)

    Mari-Liis Madisson

    2015-06-01

    .  Focusing on meaning-creation by the groupuscular extreme right, one can examine groupuscules communicating in the internet environments as different semiotic wholes, or semiospheres: these can be specific posts, popular discussion topics, or the network as a whole. The semiotic wholeness of a groupuscule is guaranteed by a boundary. By means of the boundary, a groupuscule can distinguish itself from its semiotic other, filter information from outside, and restate this in its own language. Groupuscules of the extreme right bring those people together who use the web medium both for the formation and the confirmation of their personal racial/ethnic identity. Their relatively marginal status as a „public voice“ can be explained by the fact that on the webpages we examined, a dominant strategy for identity formation was creating the image of an extreme rightist as a sufferer or victim. They often presented themselves as persecuted and unjustly excluded from public discussions. In the communications of the Estonian extreme right, the designated antagonists are the mainstream media, the European Union, and its corrupt politicians.  In terms of its internal structure, the groupuscular extreme right is heterogeneous. When a specific groupuscule enters interaction with other extreme right cells, it is no longer identical with itself, since its identity is largely determined by connecting with other groupuscules; that is, its particularity only emerges through communication with other groupuscules. The Estonian extreme right groupuscules we studied are relatively well known publicly in the so-called local counterculture; some of their articles are frequently commented and cited (on the pages we studied, reciprocal reference and quotation was frequent.  However, in every semiotic whole, dominants or nuclei develop, which, compared to more marginal semiotic units are usually more rigidly structured. Similar nuclear structures also play an important role in groupuscular identity

  5. Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.

    Science.gov (United States)

    Susswein, Lisa R; Marshall, Megan L; Nusbaum, Rachel; Vogel Postula, Kristen J; Weissman, Scott M; Yackowski, Lauren; Vaccari, Erica M; Bissonnette, Jeffrey; Booker, Jessica K; Cremona, M Laura; Gibellini, Federica; Murphy, Patricia D; Pineda-Alvarez, Daniel E; Pollevick, Guido D; Xu, Zhixiong; Richard, Gabi; Bale, Sherri; Klein, Rachel T; Hruska, Kathleen S; Chung, Wendy K

    2016-08-01

    Germ-line testing for panels of cancer genes using next-generation sequencing is becoming more common in clinical care. We report our experience as a clinical laboratory testing both well-established, high-risk cancer genes (e.g., BRCA1/2, MLH1, MSH2) as well as more recently identified cancer genes (e.g., PALB2, BRIP1), many of which have increased but less well-defined penetrance. Clinical genetic testing was performed on over 10,000 consecutive cases referred for evaluation of germ-line cancer genes, and results were analyzed for frequency of pathogenic or likely pathogenic variants, and were stratified by testing panel, gene, and clinical history. Overall, a molecular diagnosis was made in 9.0% of patients tested, with the highest yield in the Lynch syndrome/colorectal cancer panel. In patients with breast, ovarian, or colon/stomach cancer, positive yields were 9.7, 13.4, and 14.8%, respectively. Approximately half of the pathogenic variants identified in patients with breast or ovarian cancer were in genes other than BRCA1/2. The high frequency of positive results in a wide range of cancer genes, including those of high penetrance and with clinical care guidelines, underscores both the genetic heterogeneity of hereditary cancer and the usefulness of multigene panels over genetic tests of one or two genes.Genet Med 18 8, 823-832.

  6. Ultrasonic calibration and certification of V1 and V2 type reference standard blocks for use in Non-Destructive Testing

    Science.gov (United States)

    Maggi, L. E.; Silva, C. E. R.; Alvarenga, A. V.; Costa-Felix, R. P. B.

    2011-02-01

    Ultrasonic Non-Destructive Testing (US-NDT) has many industrial applications, such as flaws detection, welding integrity evaluation and solid material thickness measurement. To evaluate the instrumentation conditions, before a measurement begins, a "calibration" should be carried out with the aid of a reference standard block (RSB). Types V1 (ISO 2400) and V2 (ISO 7963) are the most widely used in US-NDT. Due their characteristics, V1 and V2 RSB can be classified as Reference Material, so that they can be certified, resulting in a Certified Reference Material (CRM). This paper describes technical aspects of a V1 and V2 RSB certification, based on ISO 2400, ISO 7963, EN 12223 and EN 27963. According the certification protocol established at Inmetro's Laboratory of Ultrasound, RSB relevant dimensions were determined through calibration. Ultrasound velocity was assessed by using a scope and a signal generator at 5 MHz. Uncertainties were determined including measurement accuracy under repeatability conditions. A complete uncertainty budget was determined for both parameters. Within the specimens used, velocities were in accordance with specifications 5920 ± 30 m/s.

  7. PET imaging of serotonin transporters with [c-11]DASB: test-retest reproducibility using a multilinear reference tissue parametric imaging method

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Seung; Janet, Sangare; Rober, B Innis [Asan Medical Center, Seoul (Korea, Republic of); Masanori, Ichise [Harvard medical school, Boston (United States)

    2005-07-01

    Parametric imaging of serotonin transporters (SERT) with [C-11]DASB PET is a useful data analysis tool. The purpose of this study was to evaluate the reproducibility of measurements of SERT binding potential (BP) and relative blood flow (R1) by a two-parameter multilinear reference tissue parametric imaging method (MRTM2) for human [C-11]DASB studies. Eight healthy subjects (M/F=3/5, 26{+-}9 y) underwent two [C-11]DASB PET scans separated by 1 h on the same day. Parametric images of BP and R1 were generated by MRTM2 using the cerebellum as a reference region. The k2'(clearance rate constant from the reference region) required by MRTM2 was estimated by the 3-parameter MRTM. Reproducibility of BP and R1 measurements were evaluated by calculating bias, variability, and reliability (r) for several representative regions of interest (ROIs). BP and R1 were estimated for ROI time activity curves (TACs) fitted by MRTM2 and were compared to those based on the parametric images. The test/retest MRTM k2' reproducibility was excellent with small bias (3%) and variability (6%), and high reliability (0.95). Retest BP values were consistently lower than those of test in all regions (a mean negative bias of {approx}6%, p <0.001). The test/retest BP variability was relatively small, ranging from 4 to 13% with r ranging from 0.44 to 0.85. In contrast to BP, test/retest R1 values were similar with negligible bias. The test/retest R1 variability was excellent and smaller than that of BP ranging from 3 to 6%, with r ranging from 0.58 to 0.95. BP and R1 values estimated by ROI TAC fitting method were slightly lower ({approx}3% and {approx}1%, respectively) than those by the parametric imaging method (P<0.001). However, the test/retest bias and variability of BP and R1 were very similar for both ROI and parametric methods. Our results suggest that [C-11]DASB parametric imaging of BP and R1 with the noninvasive MRTM2 method is reproducible and reliable for PET imaging studies of

  8. Reevaluation of the thyroidal radioactive iodine uptake test, with special reference to reversible primary hypothyroidism with elevated thyroid radioiodine uptake

    Energy Technology Data Exchange (ETDEWEB)

    Okamura, K.; Sato, K.; Ikenoue, H.; Yoshinari, M.; Nakagawa, M.; Kuroda, T.; Fujishima, M.

    1988-10-01

    The clinical significance of the thyroidal radioactive iodine uptake (RAIU) test was reevaluated in patients with various thyroid disorders. Compared with 262 normal subjects or 194 patients with euthyroid diffuse goiter with normal serum TSH levels, RAIU values were significantly higher in 100 patients with latent primary hypothyroidism (serum TSH, 5-40 mU/L). In 126 patients with overt primary hypothyroidism (serum TSH, greater than 40 mU/L), RAIU values were either extremely high (49 patients with reversible hypothyroidism and 10 patients with postpartum hypothyroidism) or low (67 patients with irreversible hypothyroidism). The increase in RAIU values in latent, or reversible overt hypothyroidism was TSH dependent, and there was a good correlation between RAIU values and serum TSH levels (r = 0.6203; P less than 0.001). In overt primary hypothyroidism, spontaneous recovery of thyroid function during iodide restriction alone occurred in 52 of 53 patients with RAIU values above 35%, in only 7 of 23 patients with RAIU values between 10-35%, and in none of 50 patients with RAIU below 10%. Thus, recovery was predicted by high RAIU values (P less than 0.001; prediction rate, 91.4%). Goiter was found in about 80% of the patients with reversible hypothyroidism, compared with only 34% of the patients with irreversible hypothyroidism. Recovery of thyroid function during iodide restriction also occurred in 71% of the patients with latent hypothyroidism. However, RAIU measurements did not predict the prognosis of patients with latent hypothyroidism. We conclude that iodine-induced reversible hypothyroidism is common in our patient population, and RAIU measurements may be helpful in determining the prognosis of patients with overt primary hypothyroidism.

  9. Equações de referência para o teste de caminhada de seis minutos em indivíduos saudáveis

    Directory of Open Access Journals (Sweden)

    Victor Zuniga Dourado

    2011-06-01

    Full Text Available O teste de caminhada de 6 minutos (TC6 tem sido amplamente utilizado no ambiente clínico. Algumas equações de referência para a previsão da distância percorrida no teste (DTC6 estão disponíveis na literatura. Esta revisão teve como objetivo discutir criticamente os achados da literatura, publicados em português e em inglês (LILACS, SCIELO, MEDLINE e PUBMED, que avaliaram os valores normais e elaboraram equações de referência para a previsão da DTC6 em indivíduos saudáveis, comparando-os aos resultados recentemente obtidos em indivíduos brasileiros. Idade, gênero, peso, estatura e índice de massa corporal foram os atributos demográficos e antropométricos mais frequentemente correlacionados com a DTC6. As equações resultantes desses atributos foram capazes de explicar entre 25 e 66% da variabilidade total da DTC6. Lamentavelmente, as equações estrangeiras não são adequadas para a população brasileira. Mesmo quando o teste é realizado sob padronização rigorosa, a diferença de performance no TC6 entre estrangeiros e brasileiros permanece, indicando a necessidade dos valores de referências específicos para cada população e/ou etnia. Nesse sentido, as equações desenvolvidas recentemente no Brasil são, provavelmente, as mais apropriadas para interpretar a performance de caminhada dos nossos compatriotas com doenças crônicas que afetam a capacidade para realizar exercícios. Estudos futuros com amostras substancialmente maiores (e.g. multicêntricos e com técnica de amostragem randomizada são necessários para que os valores de referência da DTC6 sejam mais representativos.

  10. Correlations of scores on the Gifted Evaluation Scale with those on WISC-III and Kaufman Brief Intelligence Test for students referred for Gifted Evaluation.

    Science.gov (United States)

    Levinson, E M; Folino, L

    1994-04-01

    29 students (M age of 8.0 yr.) who were referred for evaluation were administered the Gifted Evaluation Scale, the Kaufman Brief Intelligence Test, and the WISC-III. Paired t tests comparing the mean GES Quotient with the K-BIT mean IQ and WISC-III Verbal, Performance, and Full Scale IQs yielded no statistically significant differences (range of IQs = 120.6 to 122.9). While the significant correlation of the GES Quotient and WISC-III Performance IQ was .42, r = -.37 for the GES Quotient and WISC-III Verbal IQ. No significant correlation was found between the GES Quotient and the WISC-III Full Scale or K-BIT IQs. The limitations and implications of the study, with regard to the use of the Gifted Evaluation Scale, are discussed.

  11. Establishment of a reference material for standardization of the anti-complementary activity test in intravenous immunoglobulin products used in Japan: A collaborative study.

    Science.gov (United States)

    Nojima, Kiyoko; Okuma, Kazu; Ochiai, Masaki; Kuramitsu, Madoka; Tezuka, Kenta; Ishii, Mieko; Ueda, Sadao; Miyamoto, Takashi; Kamimura, Koichiro; Kou, Enki; Uchida, Sanae; Watanabe, Yoshiharu; Okada, Yoshiaki; Hamaguchi, Isao

    2017-03-01

    Aggregates of human plasma-derived intravenous immunoglobulins (IVIGs) carries a risk of severe adverse events after nonspecific complement activation induced in humans administrated. Therefore, the anti-complementary activity (ACA) test is legally required in every batch of IVIGs in Japan. However, due to the intrinsic nature of this bioassay, there might be large differences in the results of ACA tests from laboratories, even when the same batch of IVIGs was measured. Our six laboratories evaluated whether there were such differences and argued for establishment of a reference material (RM) for standardization of the ACA test. Our results revealed inter-laboratory differences in ACA values, indicating a need to establish an RM. Therefore, after ACA values in candidate RMs were measured collaboratively, one RM was selected from two candidates and unit value-assigned. The RM in fact normalized the ACA test values for samples measured in parallel at almost all the laboratories, when the values were calculated relative to the assigned unit value of the RM. Thus, we established a first RM to standardize the ACA test in Japan, which enabled each laboratory to normalize ACA values constantly for IVIGs. This indicates that the establishment of an RM can contribute to quality control of IVIGs. Copyright © 2017 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.

  12. Survival of the Unfit: Path Dependence and the Estonian Oil Shale Industry

    Energy Technology Data Exchange (ETDEWEB)

    Holmberg, Rurik

    2009-01-15

    Estonia is the only country in the world, which is totally dependent on oil shale in its energy system. Although this fossil fuel exists in enormous quantities around the world, it has so far not been utilized on a larger scale. The reasons for this have been both economic and, in recent times, ecological. It can therefore be argued that in most cases, oil shale represents an inferior solution compared to other energy sources. This work examines why a technology utilizing oil shale has developed in Estonia and why Estonia appears not to be in a position to switch to other energy sources. In this work it is claimed that oil shale actually has been an appropriate solution to short-term concerns, despite the fact that its long-term drawbacks have been identified. These circumstances led to path dependence. Once the technology was in place, it advanced along its learning curve producing a satisfactory outcome, but not an optimal one. However, this situation has been accepted due to the extremely turbulent institutional environment Estonia has undergone in the 20th century. In Sweden, a somewhat similar (but smaller) oil shale industry was shut down in the 1960s because of poor economic performance, but also because of the competition from other energy sources. Such competition did not take place in Estonia, in part due to the specific institutional set-up of the Soviet Union. This made it possible for the Estonian oil shale industry to develop further, causing the present lock-in. Today the existing infrastructure, the knowledge-base, and the particular socio-political circumstances of Estonia effectively prevent change. Furthermore, it is argued that because there was only little oil shale-related technology developed outside Estonia, most technology had to be developed domestically. This in turn has forced the Estonian oil shale industry to make several highly inconvenient alliances in order to gain room to manoeuvre. Partially as a result of this, there is today

  13. Environmental Sensitivity Index: Estonian shoreline geology classification (Gulf of Finland, Baltic Sea)

    Science.gov (United States)

    Aps, Robert; Kopti, Madli; Tõnisson, Hannes; Orviku, Kaarel; Suursaar, Ülo

    2013-04-01

    At International Maritime Organization's (IMO) Marine Environment Protection Committee's 53rd session in July 2005, the Baltic Sea was designated as a Particularly Sensitive Sea Area (PSSA). At the same time the oil transportation is growing significantly in the Baltic Sea area and especially in the Gulf of Finland exceeding 250 million tons a year by 2015. Despite of improving navigation measures there is a growing risk for incidental oil spills and associated oil pollution. Oil spill accident history and simulations show that once the oil spill at sea has occurred, it is almost impossible to prevent it from reaching ashore. Advice on sensitive shoreline likely to be impacted by the oil washing ashore is of critical importance in order to support decisions whether or not a response is necessary or what kind and extent of response is appropriate. Furthermore, choices made in cleanup strategies and the decisionmaking process in the aftermath of a spill are significantly affecting the cleanup costs. This paper introduces the Environmental Sensitivity Index (ESI) shoreline geology classification adapted and modified according to the environmental conditions of the Estonian coast of the Gulf of Finland (Baltic Sea) and ranked according to substrate type and grain size related natural persistence of oil and ease of cleanup. Relative exposure to wave (hydrodynamic energy level) and the shoreline slope are characterized and taken into account. The length of the shoreline is over 700 km. The most common shore types are till shores (40%) and sandy shores (25%). Long stretches of cliff shores (11% in total) and gravel-pebble shores (10%) on the close neighborhood of the cliffs are the most characteristic features of the Estonian coast of the Gulf of Finland. Silty shores and artificial shores make up to 7% and 6% respectively of the total shoreline length here. Over 2/3 of the shores here are with very high ESI values. Till shores are often covered by coarse gravel, pebble

  14. Survey of the Prevalence of Glucose-6-Phosphate Dehydrogenase (G6PD Deficiency in Admitted Men for Premarriage Tests in Zahedan-Iran Reference Laboratory

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    Nakhaee Ali Reza

    2009-09-01

    Full Text Available Background: GLucose-6-phosphate dehydrogenase (G6PD deficiency is the most common known enzymopathy in human. G6PD deficiency is usually asymptomatic, however, deficient individuals are at increased risk of developing acute hemolytic anemia and hyperbilirubinemia following intake of oxidative agents and fava. The objective of present study was to detect prevalence of G6PD deficiency in admitted males for premarriage tests in Zahedan Reference Laboratory. Also, we compared blood indices of normal and G6PD deficient individuals.Materials and Methods: This descriptive study was carried out on 1340 admitted males in Zahedan Reference Laboratory from February 2008 to March 2009. G6PD activity was determined in EDTA containing blood samples by qualitative fluorescence spot test, then G6PD deficiency was confirmed by quantitative spectrophotometric method. Total leukocyte count and RBC indices of G6PD deficient samples and the same number of normal samples were compared. The differences between two groups were compared using Sigmaplot software and t-Student test. A P-value less than 0.05 was considered statistically significant.Results: G6PD deficiency was found in 84 individuals of total 1340 by fluorescence spot test and confirmed in 79 by quantitative method. Therefore, prevalence of G6PD deficiency in Zahedan was estimated to be 5.9%. Comparison of deficient and normal individuals did not show significant difference in WBC count, RBC count, hemoglobin concentration, hematocrit, mean corpuscular hemoglobin (MCH and RDW-SD. However, mean corpuscular volume (MCV was significantly high and mean corpuscular hemoglobin concentration (MCHC and RDW-CV were significantly low in G6PD deficient individuals compared to those with normal enzyme level.Discussion: Present study revealed that the prevalence of G6PD deficiency in Zahedan is 5.9%. Severity of G6PD deficiency in quantitative assay indicated that class I and II are probably dominant variants in

  15. Characteristics of cyclones causing extreme sea levels in the northern Baltic Sea** The study was supported by the Estonian Ministry of Education and Research (IUT20-11 and Grant ETF9134 and by the EU Regional Development Foundation, Environmental Conservation and Environmental Technology R&D Programme Project No. 3.2.0801.12-0044.

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    Piia Post

    2014-01-01

    Full Text Available The basic parameters of extra-tropical cyclones in the northern Baltic are examined in relation to extreme sea level events at Estonian coastal stations between 1948 and 2010. The hypothesis that extreme sea level events might be caused not by one intense extra-tropical cyclone, as suggested by earlier researchers, but by the temporal clustering of cyclones in a certain trajectory corridor, is tested. More detailed analysis of atmospheric conditions at the time of the two most extreme cases support this concept: the sequence of 5 cyclones building up the extreme sea level within about 10 days was very similar in structure and periodicity.

  16. Helicobacter pylori test-and-treat program can be cost-effective to prevent gastric cancer in Taiwanese adults: referred to the nationwide reimbursement database.

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    Cheng, Hsiu-Chi; Wang, Jung-Der; Chen, Wei-Ying; Chen, Chian-Wei; Chang, Shun-Chiao; Sheu, Bor-Shyang

    2015-04-01

    Helicobacter pylori infection increases the risk of gastric cancer. The study aimed to compare cost-effectiveness ratios of H. pylori test-and-treat programs to prevent gastric cancer in Taiwan, referring to the nationwide reimbursement database and expected years of life lost. During 1998-2009, there were 12,857 females and 24,945 males with gastric adenocarcinoma in Taiwan National Cancer Registry. They were followed up to 2010 and linked to the reimbursement database of National Health Insurance and the national mortality registry to determine lifetime health expenditures and expected years of life lost. Cost-effectiveness ratios of H. pylori test-and-treat programs for prevention of gastric adenocarcinoma were compared between screenings with (13) C-urea breath test and with anti-H. pylori IgG. The test-and-treat program with anti-H. pylori IgG to prevent gastric adenocarcinoma had lower incremental cost-effectiveness ratios than that with (13) C-urea breath test in both sexes (females: 244 vs 1071 US dollars/life-year; males: 312 vs 1431 US dollars/life-year). Cost saving would be achieved in an endemic area where H. pylori prevalence was >73.5%, or by selecting subpopulations with high absolute risk reduction rates of cancer after eradication. Moreover, expected years of life lost of gastric adenocarcinoma were higher and the incremental cost-effectiveness ratios of test-and-treat programs were more cost-effective in young adults (30-69 y/o) than in elders (≥70 y/o). The test-and-treat program with anti-H. pylori IgG shall be cost-effective to prevent gastric adenocarcinoma in a high endemic area, especially beginning at 30 years of age when H. pylori prevalence rates become stabilized. © 2014 John Wiley & Sons Ltd.

  17. Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

    Science.gov (United States)

    Aschner, Michael; Ceccatelli, Sandra; Daneshian, Mardas; Fritsche, Ellen; Hasiwa, Nina; Hartung, Thomas; Hogberg, Helena T.; Leist, Marcel; Li, Abby; Mundy, William R.; Padilla, Stephanie; Piersma, Aldert H.; Bal-Price, Anna; Seiler, Andrea; Westerink, Remco H.; Zimmer, Bastian; Lein, Pamela J.

    2016-01-01

    Summary There is a paucity of information concerning the developmental neurotoxicity (DNT) hazard posed by industrial and environmental chemicals. New testing approaches will most likely be based on batteries of alternative and complementary (non-animal) tests. As DNT is assumed to result from the modulation of fundamental neurodevelopmental processes (such as neuronal differentiation, precursor cell migration or neuronal network formation) by chemicals, the first generation of alternative DNT tests target these processes. The advantage of such types of assays is that they capture toxicants with multiple targets and modes-of-action. Moreover, the processes modelled by the assays can be linked to toxicity endophenotypes, i.e. alterations in neural connectivity that form the basis for neurofunctional deficits in man. The authors of this review convened in a workshop to define criteria for the selection of positive/negative controls, to prepare recommendations on their use, and to initiate the setup of a directory of reference chemicals. For initial technical optimization of tests, a set of >50 endpoint-specific control compounds was identified. For further test development, an additional “test” set of 33 chemicals considered to act directly as bona fide DNT toxicants is proposed, and each chemical is annotated to the extent it fulfills these criteria. A tabular compilation of the original literature used to select the test set chemicals provides information on statistical procedures, and toxic/non-toxic doses (both for pups and dams). Suggestions are provided on how to use the >100 compounds (including negative controls) compiled here to address specificity, adversity and use of alternative test systems. PMID:27452664

  18. STATIC AND DYNAMIC STATES: THE CASE OF ESTONIAN STATIVE COLOUR EXPRESSIONS

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    Geda Paulsen

    2012-01-01

    Full Text Available The aim of this study is to account for stative situations through the example of structurally different but semantically close colour expressions: the Estonian stative verbs derived from colour adjectives and colour adjectives appearing as the predicative. Stative verbs are assumed to be similar to copula constructions, with the aspectual distinction of temporary/permanent property. In this article, the stative colour expressions are analysed using the linguistic diagnostics developed for the determination of ontological properties of different types of states – the sc. Davidsonian and Kimian states(see e.g. Maienborn 2003. Analysis reveals that the copula construction with colour adjective as predicative is ambiguous, inclining to the Kimian states but also assigning properties characteristic to the Davidsonian states; the stative colour verbs, in turn, are true examples of Davidsonian states. In addition to the examination of the stative properties, the conceptual structure analysis of the colour expressions instantiating stative and dynamic states is given. The observer’s evaluation of the coloured object as a mental image is treated as part of the lexical information of the colour statives. Also, sentential and contextual phenomena of the colour statives are discussed.

  19. Sexual behavior, depressive feelings, and suicidality among Estonian school children aged 13 to 15 years.

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    Heidmets, L; Samm, A; Sisask, M; Kõlves, K; Aasvee, K; Värnik, A

    2010-01-01

    The present paper is based on a WHO Collaborative Cross-National Study "Health Behavior in School-Aged Children (HBSC)." It aimed at describing and analyzing how the sexual behaviors of 13- to 15-year-old Estonian school children were associated with self-reported depressive feelings and suicidality. Distinctive behavioral traits in relation to age of first sexual intercourse were also investigated. Self-reported questionnaires from school children (n = 3,055) were analyzed. In total, 15.2% of school children reported being nonvirgin. Among 13-year-olds, 2.9% of girls and 6.8% of boys were nonvirgins. Approximately 25% of the 15-year-old girls and boys were nonvirgins. The likelihood of depressive feelings and suicidal ideation increased significantly in both genders with loss of virginity. Boys who had lost their virginity at 13 years or younger were 4.2 times more likely to have suicidal thoughts; comparable girls were 7.8 times more likely to have suicidal thoughts. Compared to virgins, youths who had lost their virginity reported poor self-assessed health and more risk behaviors in themselves and their peers. Experiences of sexual intercourse increased the odds ratios for depressive feelings and suicidality. The earlier sexual intercourse was initiated, the greater were the odds of lower mental well-being. Risk behaviors emerged as a complex phenomenon requiring complex prevention.

  20. Reported contraceptive use, risk behaviours and STIs among military conscripts in Estonian defence forces.

    Science.gov (United States)

    David Parker, R; Regier, Michael D; Widmeyer, Joseph; Honaker, John; Rüütel, Kristi

    2015-10-01

    Limited research exists on sexually transmitted infection (STI) and risk behaviour among military personnel. Published research on condom use and types of contraceptives used yield mixed results, yet, the perception that military members are at higher risk for STIs remains. The objectives of this cross-sectional study were to measure factors such as condom use, contraceptive methods, and risky behaviours (i.e. drug use and sex with commercial sex workers) and investigate differences between ethnic groups, where culture could influence behaviour. Data were collected from a recruited population of 584 male, military conscripts in northeastern Europe. Using multinomial logistic regression models, statistically significant findings include an interaction between the use of contraceptive methods of Russians with casual partners and ethnicity, with higher odds of effective methods used among Estonians with regular partners (OR = 8.13) or casual partners (OR = 11.58) and Russians with regular partners (OR = 4.98). Effective contraceptive methods used less frequently with casual partners by ethnic Russians is important in providing education and risk reduction services to young, male conscripts. These findings may be used as a baseline to inform health education and STI prevention programmes tailored to military members in Eastern Europe in the absence of other published studies. © The Author(s) 2015.

  1. Nordic-Baltic cooperation in adult education: A collective story of Estonian adult educators

    Science.gov (United States)

    Jõgi, Larissa; Karu, Katrin

    2017-03-01

    Adult Education has many values, including experiences and co-operation among people, and the fact that adult education is full of stories from adult educators, which can help to understand trends in the past and developments in the present. Established in 1991 as part of a more general regional cooperation among five Nordic and three Baltic countries (NB8), Nordic-Baltic cooperation in adult education has been mutually enriching and has resulted in the growth of a professional network. The cooperation has led participants through a time of new sources of values, knowledge and contacts, socialisation and transformation, inspiration and challenges, which has influenced their experiences and professional identities. This paper is based on the results of a study entitled "Nordic-Baltic cooperation in adult education: Experience and stories" and focuses on the experiences and professional identities of two generations of Estonian adult educators. The empirical data for the study were collected using narrative-biographical interviews. The paper discusses two research questions: (1) What is the perception and influence of experiences for adult educators? and (2) How have their experiences influenced the professional identity of adult educators?

  2. Symptoms of anxiety and depression in Estonian medical students with sleep problems.

    Science.gov (United States)

    Eller, Triin; Aluoja, Anu; Vasar, Veiko; Veldi, Marlit

    2006-01-01

    High emotional stress in medical students has been observed in many studies. Our aim in this article was to assess the prevalence of symptoms of anxiety and depression among Estonian medical students and to find relationships between sleep complaints and emotional symptoms. The study group consisted of 413 medical students, ages 19-33 years, at the University of Tartu. Each was asked to complete two questionnaires: the Emotional State Questionnaire (EST-Q), containing 28 questions, and the Questionnaire on Sleep and Daytime Habits, with 25 questions. The anxiety and depression subscales from the EST-Q were applied. From the study group, 21.9% students had symptoms of anxiety, and 30.6% had symptoms of depression. The frequency of anxiety and depressive symptoms was higher in females. In regression and multiple regression analysis, we determined which sleep problems were related to emotional symptoms. The associations were different for men and women. In women, anxiety remained significantly related to waking up because of nightmares and feeling tired in the morning; depressive symptoms were related to difficulties in getting to sleep at night, waking up because of nightmares and nocturnal eating habits, daytime sleepiness, and sleepiness during school lessons. In men, significant relations were clear only for depression: difficulties in falling asleep at night before an exam and subjective sleep quality. The study demonstrated that a high percentage of medical students had emotional symptoms. We found that some sleep problems indicated underlying symptoms of anxiety and depression. (c) 2006 Wiley-Liss, Inc.

  3. A study of bovine mastitis, milking procedures and management practices on 25 Estonian dairy herds

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    Spiridonova Irina

    2006-11-01

    Full Text Available Abstract Background Mastitis prevalence, milking procedures and management practices were investigated in 25 big dairy herds supplying milk to an Estonian dairy company. The aim of the study was to provide information for the company to be used in their new udder health improvement program to be set up after the completion of this study. Methods Quarter milk samples were collected from 3,166 cows for bacterial analysis and SCC (somatic cell counting. During the farm visit the veterinarian filled in a questionnaire about milking procedures and management practices with the help of farm managers. If the milk SCC of a cow or of a quarter exceeded 200,000/ml, the cow was defined as having mastitis. Results The percentage of cows having inflammation in one or more quarters measured by SCC (200,000/ml was 52.7%. Corynebacterium bovis, Staphylococcus aureus and coagulase negative staphylococci were the most common bacterial isolates. Women as farm owners, and participating in the milking, were associated with lower mastitis prevalence on the farm. Peat bedding was associated with higher mastitis prevalence. Conclusion We demonstrated relatively high mastitis prevalence in this study. Contagious bacteria (eg. S. aureus, C. bovis, S. agalactiae and coagulase negative staphylococci caused most of the infections. These infections are usually spread from cow to cow at milking if the milking hygiene is not good enough. The mastitis situation could be improved by improving milking procedures and hygiene.

  4. Trade Union Responses to Transnational Labour Mobility in the Finnish-Estonian Context

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    Rolle Alho

    2013-09-01

    Full Text Available This article examines trade union strategies in relation to labor migration in Estonia and Finland, drawing on face-to-face interviews with trade unionists and official union statements. The study considers the national trade union strategies located in two separate but interconnected localities that represent different approaches to market economy. Previous research suggests that the national industrial relations system is a key factor in explaining unions’ labor migration strategies. Unions operating in liberal market economies are claimed to be more open toward immigration and more inclusive toward immigrants than unions in coordinated markets. This study analyzes the extent to which this theory holds in the context of Estonia and Finland—Finland representing a coordinated market economy and Estonia a liberal market economy. Furthermore, the analysis examines how the emergence of a translocal labor market, resulting from the geographical vicinity and linguistic affinity between Finland and Estonia as well as from free mobility within the EU, is reflected in trade union approaches to labor migration. The study finds that Finnish trade union strategies influence labor mobility, whereas Estonian trade unions remain bystanders in the issue.

  5. Survey of the diagnostic retooling process in national TB reference laboratories, with special focus on rapid speciation tests endorsed by WHO in 2007.

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    Sanne C van Kampen

    Full Text Available BACKGROUND: Successful integration of new diagnostics in national tuberculosis (TB control programs, also called 'retooling', is highly dependent on operational aspects related to test availability, accessibility and affordability. This survey aimed to find out whether recommendations to use new diagnostics lead to successful retooling in high TB endemic countries, using immunochromatographic tests (ICTs for TB culture speciation as a case study. ICTs are recommended to accurately confirm the presence of bacteria of the Mycobacterium tuberculosis complex in liquid culture isolates. METHODS AND FINDINGS: Questionnaires were sent to national TB reference laboratories (NRLs in 42 high TB endemic countries to address their access to information on ICT implementation, logistics related to availability, accessibility and affordability of ICTs, and testing algorithms. Results from 16 responding countries indicated that half of the NRLs were aware of the contents of WHO guidance documents on liquid culture and ICT implementation, as well as their eligibility for a negotiated pricing agreement for ICT procurement. No major issues with availability and accessibility of ICTs were raised. When asked about testing algorithms, ICTs were not used as stand-alone or first test for TB culture identification as recommended by WHO. CONCLUSIONS: The low response rate was a limitation of this survey and together with NRLs managers' unawareness of global guidance, suggests a lack of effective communication between partners of the global laboratory network and NRLs. TB tests could become more affordable to high TB endemic countries, if the possibility to negotiate lower prices for commercial products is communicated to them more successfully. NRLs need additional guidance to identify where available technologies can be most usefully implemented and in what order, taking into account long-term laboratory strategies.

  6. Survey of the diagnostic retooling process in national TB reference laboratories, with special focus on rapid speciation tests endorsed by WHO in 2007.

    Science.gov (United States)

    van Kampen, Sanne C; Oskam, Linda; Tuijn, Coosje J; Klatser, Paul R

    2012-01-01

    Successful integration of new diagnostics in national tuberculosis (TB) control programs, also called 'retooling', is highly dependent on operational aspects related to test availability, accessibility and affordability. This survey aimed to find out whether recommendations to use new diagnostics lead to successful retooling in high TB endemic countries, using immunochromatographic tests (ICTs) for TB culture speciation as a case study. ICTs are recommended to accurately confirm the presence of bacteria of the Mycobacterium tuberculosis complex in liquid culture isolates. Questionnaires were sent to national TB reference laboratories (NRLs) in 42 high TB endemic countries to address their access to information on ICT implementation, logistics related to availability, accessibility and affordability of ICTs, and testing algorithms. Results from 16 responding countries indicated that half of the NRLs were aware of the contents of WHO guidance documents on liquid culture and ICT implementation, as well as their eligibility for a negotiated pricing agreement for ICT procurement. No major issues with availability and accessibility of ICTs were raised. When asked about testing algorithms, ICTs were not used as stand-alone or first test for TB culture identification as recommended by WHO. The low response rate was a limitation of this survey and together with NRLs managers' unawareness of global guidance, suggests a lack of effective communication between partners of the global laboratory network and NRLs. TB tests could become more affordable to high TB endemic countries, if the possibility to negotiate lower prices for commercial products is communicated to them more successfully. NRLs need additional guidance to identify where available technologies can be most usefully implemented and in what order, taking into account long-term laboratory strategies.

  7. Capacitive sensing of test mass motion with nanometer precision over millimeter-wide sensing gaps for space-borne gravitational reference sensors

    Science.gov (United States)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Bassan, M.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, A. M.; Danzmann, K.; de Deus Silva, M.; De Rosa, R.; Di Fiore, L.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E. D.; Flatscher, R.; Freschi, M.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Grado, A.; Grimani, C.; Grzymisch, J.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C. J.; Lobo, J. A.; Lloro, I.; Liu, L.; López-Zaragoza, J. P.; Maarschalkerweerd, R.; Mance, D.; Martín, V.; Martin-Polo, L.; Martino, J.; Martin-Porqueras, F.; Madden, S.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mendes, L.; Meshksar, N.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Robertson, D. I.; Rozemeijer, H.; Rivas, F.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Stanga, R.; Sumner, T. J.; Texier, D.; Thorpe, J. I.; Trenkel, C.; Tröbs, M.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Wass, P. J.; Wealthy, D.; Weber, W. J.; Wissel, L.; Wittchen, A.; Zambotti, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.; LISA Pathfinder Collaboration

    2017-09-01

    We report on the performance of the capacitive gap-sensing system of the Gravitational Reference Sensor on board the LISA Pathfinder spacecraft. From in-flight measurements, the system has demonstrated a performance, down to 1 mHz, that is ranging between 0.7 and 1.8 aF Hz-1 /2 . That translates into a sensing noise of the test mass motion within 1.2 and 2.4 nm Hz-1 /2 in displacement and within 83 and 170 nrad Hz-1 /2 in rotation. This matches the performance goals for LISA Pathfinder, and it allows the successful implementation of the gravitational waves observatory LISA. A 1 /f tail has been observed for frequencies below 1 mHz, the tail has been investigated in detail with dedicated in-flight measurements, and a model is presented in the paper. A projection of such noise to frequencies below 0.1 mHz shows that an improvement of performance at those frequencies is desirable for the next generation of gravitational reference sensors for space-borne gravitational waves observation.

  8. Are Health State Valuations from the General Public Biased? A Test of Health State Reference Dependency Using Self-assessed Health and an Efficient Discrete Choice Experiment.

    Science.gov (United States)

    Jonker, Marcel F; Attema, Arthur E; Donkers, Bas; Stolk, Elly A; Versteegh, Matthijs M

    2016-10-27

    Health state valuations of patients and non-patients are not the same, whereas health state values obtained from general population samples are a weighted average of both. The latter constitutes an often-overlooked source of bias. This study investigates the resulting bias and tests for the impact of reference dependency on health state valuations using an efficient discrete choice experiment administered to a Dutch nationally representative sample of 788 respondents. A Bayesian discrete choice experiment design consisting of eight sets of 24 (matched pairwise) choice tasks was developed, with each set providing full identification of the included parameters. Mixed logit models were used to estimate health state preferences with respondents' own health included as an additional predictor. Our results indicate that respondents with impaired health worse than or equal to the health state levels under evaluation have approximately 30% smaller health state decrements. This confirms that reference dependency can be observed in general population samples and affirms the relevance of prospect theory in health state valuations. At the same time, the limited number of respondents with severe health impairments does not appear to bias social tariffs as obtained from general population samples. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  9. Omaeluloolisus nullindatel / Estonian Life Writing of the 2000s as a Continuity Over the Post-Soviet Period

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    Rutt Hinrikus

    2013-06-01

    Full Text Available A distinctive feature of the (literary culture of the 2000s is a sudden increase in the publication of works of life writing in different genres. Although life writing as a phenomenon has received considerably more critical attention in recent years, it has not yet settled within the literary canon, and theoretical debates concerning its diverse textual practises are still in initial phases. The current article provides an overview of Estonian life writing of the 2000s, viewing the emergence of new forms, themes and perspectives as a continuity within the wider framework of the post-Soviet period and in comparison with some recent developments and theoretical foci of life writing studies in general.The processes of the construction of subjectivity and identity in a number of autobiographical writings published in the first half of the 2000s can be traced back to the emergence of Estonian “memorial culture” in the late 1980s and 1990s, where oral and written testimonial accounts of personal experience focusing on the period of the Soviet occupation played an important role in the process of dismantling the official Soviet discourses of history and contributed to the process of regaining independence. A number of life writing texts by well-known Estonian literary figures published in the mid-2000s employ modes of collective and individual self-conception and self-reflection similar to those prevalent in the texts of life stories. No longer employed for the purposes of implementing socio-political change, these works confirm and consolidate such modes of identification and self-representation within the framework of (literary culture. Another important trend of Estonian life writing of the 2000s involves “textual games”, where lived experience and the construction of fictional worlds are intertwined in a complex and self-conscious manner. Visible most strongly in the work of Tõnu Õnnepalu and Madis Kõiv, this feature of Estonian life

  10. Seltsi muuseumist riigi keskmuuseumiks: ikka ajutiste lahendustega / Changes in the Estonian National Museum from 1909 to the present.

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    Krista Aru

    2011-01-01

    Full Text Available Changes in the Estonian National Museum from 1909 to the presentThe Estonian National Museum was founded in Tartu in 1909 as part of the national movement. With its activities and connections in society, the ENM helped create Estonian society, the nation’s collective memory and identity.The ENM has always been – despite the changing locations, names, and content – one of the symbols of national identity. But at the same time, ENM has never had its own building designed specially for the museum’s purposes.Since 1909 there have been several attempts to establish a home for the ENM. At first (1909–1923, Estonian society wanted to establish the museum in the center of Tartu. The museum was intended to become a key institution of the growing nation and establishing the nation’s identity.At last in 1923 the ENM secured the Raadi manor, outside the center of the city, in a beautiful park, near the lake with its boats and water attractions. In this manor the first permanent exhibition of mainly 19th century Estonian peasant life was compiled, and the ENM operated in the Raadi manor from 1923–1940 as the “Estonian’s own museum” The years of alternating occupations, World War II, and political terror damaged and destroyed the whole society. The Raadi manor was destroyed in the war too, and the ENM itself was divided into two parts – the State Ethnographic Museum and the State Literary Museum. The collections of the ENM were given to Tallinn and to many different places inside and outside Tartu. Then began “the period of temporary location” that continues today. The museum is located in several places in the city of Tartu.In 1988, the prior name of the State Ethnographic Museum – the Estonian National Museum – was reinstated. Since the 1990s there have been many attempts to secure a special building for the ENM. Now, at last, as a result of serious economic pressure, we are closer to this goal than ever. During the last five

  11. Single-Patient Molecular Testing with NanoString nCounter Data Using a Reference-Based Strategy for Batch Effect Correction.

    Science.gov (United States)

    Talhouk, Aline; Kommoss, Stefan; Mackenzie, Robertson; Cheung, Martin; Leung, Samuel; Chiu, Derek S; Kalloger, Steve E; Huntsman, David G; Chen, Stephanie; Intermaggio, Maria; Gronwald, Jacek; Chan, Fong C; Ramus, Susan J; Steidl, Christian; Scott, David W; Anglesio, Michael S

    2016-01-01

    A major weakness in many high-throughput genomic studies is the lack of consideration of a clinical environment where one patient at a time must be evaluated. We examined generalizable and platform-specific sources of variation from NanoString gene expression data on both ovarian cancer and Hodgkin lymphoma patients. A reference-based strategy, applicable to single-patient molecular testing is proposed for batch effect correction. The proposed protocol improved performance in an established Hodgkin lymphoma classifier, reducing batch-to-batch misclassification while retaining accuracy and precision. We suggest this strategy may facilitate development of NanoString and similar molecular assays by accelerating prospective validation and clinical uptake of relevant diagnostics.

  12. Single-Patient Molecular Testing with NanoString nCounter Data Using a Reference-Based Strategy for Batch Effect Correction.

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    Aline Talhouk

    Full Text Available A major weakness in many high-throughput genomic studies is the lack of consideration of a clinical environment where one patient at a time must be evaluated. We examined generalizable and platform-specific sources of variation from NanoString gene expression data on both ovarian cancer and Hodgkin lymphoma patients. A reference-based strategy, applicable to single-patient molecular testing is proposed for batch effect correction. The proposed protocol improved performance in an established Hodgkin lymphoma classifier, reducing batch-to-batch misclassification while retaining accuracy and precision. We suggest this strategy may facilitate development of NanoString and similar molecular assays by accelerating prospective validation and clinical uptake of relevant diagnostics.

  13. Establishing quality control ranges for antimicrobial susceptibility testing of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus: a cornerstone to develop reference strains for Korean clinical microbiology laboratories.

    Science.gov (United States)

    Hong, Sung Kuk; Choi, Seung Jun; Shin, Saeam; Lee, Wonmok; Pinto, Naina; Shin, Nari; Lee, Kwangjun; Hong, Seong Geun; Kim, Young Ah; Lee, Hyukmin; Kim, Heejung; Song, Wonkeun; Lee, Sun Hwa; Yong, Dongeun; Lee, Kyungwon; Chong, Yunsop

    2015-11-01

    Quality control (QC) processes are being performed in the majority of clinical microbiology laboratories to ensure the performance of microbial identification and antimicrobial susceptibility testing by using ATCC strains. To obtain these ATCC strains, some inconveniences are encountered concerning the purchase cost of the strains and the shipping time required. This study was focused on constructing a database of reference strains for QC processes using domestic bacterial strains, concentrating primarily on antimicrobial susceptibility testing. Three strains (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus) that showed legible results in preliminary testing were selected. The minimal inhibitory concentrations (MICs) and zone diameters (ZDs) of eight antimicrobials for each strain were determined according to the CLSI M23. All resulting MIC and ZD ranges included at least 95% of the data. The ZD QC ranges obtained by using the CLSI method were less than 12 mm, and the MIC QC ranges extended no more than five dilutions. This study is a preliminary attempt to construct a bank of Korean QC strains. With further studies, a positive outcome toward cost and time reduction can be anticipated.

  14. Establishing Quality Control Ranges for Antimicrobial Susceptibility Testing of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus: A Cornerstone to Develop Reference Strains for Korean Clinical Microbiology Laboratories

    Science.gov (United States)

    Hong, Sung Kuk; Choi, Seung Jun; Shin, Saeam; Lee, Wonmok; Pinto, Naina; Shin, Nari; Lee, Kwangjun; Hong, Seong Geun; Kim, Young Ah; Lee, Hyukmin; Kim, Heejung; Song, Wonkeun; Lee, Sun Hwa; Lee, Kyungwon; Chong, Yunsop

    2015-01-01

    Quality control (QC) processes are being performed in the majority of clinical microbiology laboratories to ensure the performance of microbial identification and antimicrobial susceptibility testing by using ATCC strains. To obtain these ATCC strains, some inconveniences are encountered concerning the purchase cost of the strains and the shipping time required. This study was focused on constructing a database of reference strains for QC processes using domestic bacterial strains, concentrating primarily on antimicrobial susceptibility testing. Three strains (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus) that showed legible results in preliminary testing were selected. The minimal inhibitory concentrations (MICs) and zone diameters (ZDs) of eight antimicrobials for each strain were determined according to the CLSI M23. All resulting MIC and ZD ranges included at least 95% of the data. The ZD QC ranges obtained by using the CLSI method were less than 12 mm, and the MIC QC ranges extended no more than five dilutions. This study is a preliminary attempt to construct a bank of Korean QC strains. With further studies, a positive outcome toward cost and time reduction can be anticipated. PMID:26354353

  15. Estimation of sensitivity, specificity and predictive values of two serologic tests for the detection of antibodies against Actinobacillus pleuropneumoniae serotype 2 in the absence of a reference test (gold standard)

    DEFF Research Database (Denmark)

    Enøe, Claes; Andersen, Søren; Sørensen, Vibeke

    2001-01-01

    Latent-class models were used to determine the sensitivity, specificity and predictive values of a polyclonal blocking enzyme-linked immunosorbent assay (ELISA) and a modified complement-fixation test (CFT) when there was no reference test. The tests were used for detection of antibodies against.......9-95.3%) and of the CFT were 90.6% (86.0-95.3%) and 98.7% (98.0-99.3%). The sensitivity and specificity of a combined test, where the CFT is subsequently applied to the pig sera that test positive in the ELISA, A ere estimated at 90.2% (85.6-95.0%) and 99.9% (99.8-100%), respectively. The cost of the combined test...... independence was assumed to models allowing for conditional dependence, given the true disease status. No strong evidence of conditional dependence in either test sensitivity or specificity was found. Assuming independence, maximum-likelihood estimates and 95% confidence intervals of the sensitivity...

  16. Applying the Writing Scales of the "Common European Framework of Reference for Languages" to the New HSK Test of Proficiency in Chinese: Realities, Problems and Some Suggestions for Chinese Language Teachers and Learners

    Science.gov (United States)

    Hsiao, Ya Ping; Broeder, Peter

    2013-01-01

    This article explores levels of proficiency in Chinese with reference to the new HSK (Hanyu Shuiping Kaoshi) Chinese Proficiency Test and the "Common European Framework of Reference for Languages" (CEFR). Special attention is given to learning and teaching the writing of Chinese characters and the use of Pinyin, a phonetic Romanization…

  17. The relationship between history and physical examination findings and the outcome of electrodiagnostic testing in patients with sciatica referred to physical therapy.

    Science.gov (United States)

    Savage, Nathan J; Fritz, Julie M; Thackeray, Anne

    2014-07-01

    Cross-sectional diagnostic accuracy study. To investigate the relationship between history and physical examination findings and the outcome of electrodiagnostic testing in patients with sciatica referred to physical therapy. Electrodiagnostic testing is routinely used to evaluate patients with sciatica. Recent evidence suggests that the presence of radiculopathy identified with electrodiagnostic testing may predict better functional outcomes in these patients. While some patient history and physical examination findings have been shown to predict the presence of disc herniation or neurological insult, little is known about their relationship to the results of electrodiagnostic testing. Electrodiagnostic testing was performed on 38 patients with sciatica who participated in a randomized trial that compared different physical therapy interventions. The diagnostic gold standard was the presence or absence of radiculopathy, based on the results of the needle electromyographic examination. Diagnostic sensitivity and specificity values were calculated, along with corresponding likelihood ratios, for select patient history and physical examination variables. No significant relationship was found between select patient history and physical examination findings, analyzed individually or in combination, and the outcome of electrodiagnostic testing. Diagnostic sensitivity values ranged from 0.03 (95% confidence interval [CI]: 0.00, 0.24) to a high of 0.95 (95% CI: 0.72, 0.99), and specificity values ranged from 0.10 (95% CI: 0.02, 0.34) to a high of 0.95 (95% CI: 0.72, 0.99). Positive likelihood ratios ranged from 0.15 (95% CI: 0.01, 2.87) to a high of 2.33 (95% CI: 0.71, 7.70), and negative likelihood ratios ranged from 2.00 (95% CI: 0.35, 11.48) to a low of 0.50 (95% CI: 0.03, 8.10). In this investigation, the relationship between patient history and physical examination findings and the outcome of electrodiagnostic testing among patients with sciatica was not found to be

  18. Bernhard Linde. Noor-Eesti vooriülem. Bernhard Linde. Leader of the Young Estonian Pack

    OpenAIRE

    Jaanus Kulli

    2012-01-01

    Bernhard Linde (1886–1954) was a recognized and prolific Estonian theatre critic of the first quarter of the 20th century, who mediated and propagated western as well as eastern European theatrical innovations. In addition, he was active as a literary and art critic, publisher, and proponent of libraries, to a modest extent he was a prose writer and poet. Unquestionably, however, Bernhard Linde’s most prominent role was as one of the founding members of the literary movement Young Estonia. He...

  19. Linking English-Language Test Scores onto the Common European Framework of Reference: An Application of Standard-Setting Methodology. TOEFL iBT Research Report TOEFL iBt-06. ETS RR-08-34

    Science.gov (United States)

    Tannenbaum, Richard J.; Wylie, E. Caroline

    2008-01-01

    The Common European Framework of Reference (CEFR) describes language proficiency in reading, writing, speaking, and listening on a 6-level scale. In this study, English-language experts from across Europe linked CEFR levels to scores on three tests: the TOEFL® iBT test, the TOEIC® assessment, and the TOEIC "Bridge"™ test.…

  20. 40 CFR Table E-1 to Subpart E of... - Summary of Test Requirements for Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5

    Science.gov (United States)

    2010-07-01

    ... Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5 E Table E-1 to Subpart E of Part 53..., Subpt. E, Table E-1 Table E-1 to Subpart E of Part 53—Summary of Test Requirements for Reference and Class I Equivalent Methods for PM2.5 and PM10-2.5 Subpart E procedure Performance test Performance...

  1. The Baltic Klint beneath the central Baltic Sea and its comparison with the North Estonian Klint

    Science.gov (United States)

    Tuuling, Igor; Flodén, Tom

    2016-06-01

    Along its contact with the Baltic Shield, the margin of the East European Platform reveals a well-developed, flooded terraced relief. The most striking and consistent set of escarpments at the contact of the Lower Palaeozoic calcareous and terrigenous rocks, known as the Baltic Klint (BK), extends from northwest of Russia to the Swedish island of Öland. Marine seismic reflection profiling in 1990-2004 revealed the central Baltic Sea Klint (BSK) section in detail and enabled comparison of its geology/geomorphology with a classical klint-section onshore, namely the North Estonian Klint (NEK). The conception of the BK onshore, which is based on the land-sea separating terraced relief in northern Estonia, is not fully applicable beneath the sea. Therefore, we consider that the BSK includes the entire terraced Cambrian outcrop. We suggest the term "Baltic Klint Complex" to include the well-terraced margin of the Ordovician limestone outcrop, which is weakly developed in Estonia. Because of a steady lithological framework of the bedrock layers across the southern slope of the Fennoscandian Shield, the central BSK in the western and the NEK in the eastern part of the Baltic Homocline have largely identical morphologies. The North Estonian Ordovician limestone plateau with the calcareous crest of the BK extends across the central Baltic Sea, whereas morphological changes/variations along the Klint base occur due to the east-westerly lithostratigraphic/thickness changes in the siliciclastic Cambrian sequence. The verge of the NEK, located some 30-50 m above sea level, starts to drop in altitude as its east-westerly course turns to northeast-southwest in western Estonia. Further westwards, the BK shifts gradually into southerly deepening (0.1-0.2°) layers as its crest drops to c. 150 m below sea level (b.s.l.) near Gotska Sandön. This course change is accompanied by a considerable decrease in thickness of the platform sedimentary cover, as below the central Baltic Sea the

  2. Normative reference values for the 20 m shuttle‐run test in a population‐based sample of school‐aged youth in Bogota, Colombia: the FUPRECOL study

    Science.gov (United States)

    Palacios‐López, Adalberto; Humberto Prieto‐Benavides, Daniel; Enrique Correa‐Bautista, Jorge; Izquierdo, Mikel; Alonso‐Martínez, Alicia; Lobelo, Felipe

    2016-01-01

    Abstract Objectives Our aim was to determine the normative reference values of cardiorespiratory fitness (CRF) and to establish the proportion of subjects with low CRF suggestive of future cardio‐metabolic risk. Methods A total of 7244 children and adolescents attending public schools in Bogota, Colombia (55.7% girls; age range of 9–17.9 years) participated in this study. We expressed CRF performance as the nearest stage (minute) completed and the estimated peak oxygen consumption (V˙O2peak). Smoothed percentile curves were calculated. In addition, we present the prevalence of low CRF after applying a correction factor to account for the impact of Bogota's altitude (2625 m over sea level) on CRF assessment, and we calculated the number of participants who fell below health‐related FITNESSGRAM cut‐points for low CRF. Results Shuttles and V˙O2peak were higher in boys than in girls in all age groups. In boys, there were higher levels of performance with increasing age, with most gains between the ages of 13 and 17. The proportion of subjects with a low CRF, suggestive of future cardio‐metabolic risk (health risk FITNESSGRAM category) was 31.5% (28.2% for boys and 34.1% for girls; X2 P = .001). After applying a 1.11 altitude correction factor, the overall prevalence of low CRF was 11.5% (9.6% for boys and 13.1% for girls; X2 P = .001). Conclusions Our results provide sex‐ and age‐specific normative reference standards for the 20 m shuttle‐run test and estimated V˙O2peak values in a large, population‐based sample of schoolchildren from a large Latin‐American city at high altitude. PMID:27500986

  3. Normative reference values for the 20 m shuttle-run test in a population-based sample of school-aged youth in Bogota, Colombia: the FUPRECOL study.

    Science.gov (United States)

    Ramírez-Vélez, Robinson; Palacios-López, Adalberto; Humberto Prieto-Benavides, Daniel; Enrique Correa-Bautista, Jorge; Izquierdo, Mikel; Alonso-Martínez, Alicia; Lobelo, Felipe

    2017-01-01

    Our aim was to determine the normative reference values of cardiorespiratory fitness (CRF) and to establish the proportion of subjects with low CRF suggestive of future cardio-metabolic risk. A total of 7244 children and adolescents attending public schools in Bogota, Colombia (55.7% girls; age range of 9-17.9 years) participated in this study. We expressed CRF performance as the nearest stage (minute) completed and the estimated peak oxygen consumption (V˙O2peak ). Smoothed percentile curves were calculated. In addition, we present the prevalence of low CRF after applying a correction factor to account for the impact of Bogota's altitude (2625 m over sea level) on CRF assessment, and we calculated the number of participants who fell below health-related FITNESSGRAM cut-points for low CRF. Shuttles and V˙O2peak were higher in boys than in girls in all age groups. In boys, there were higher levels of performance with increasing age, with most gains between the ages of 13 and 17. The proportion of subjects with a low CRF, suggestive of future cardio-metabolic risk (health risk FITNESSGRAM category) was 31.5% (28.2% for boys and 34.1% for girls; X2 P = .001). After applying a 1.11 altitude correction factor, the overall prevalence of low CRF was 11.5% (9.6% for boys and 13.1% for girls; X2 P = .001). Our results provide sex- and age-specific normative reference standards for the 20 m shuttle-run test and estimated V˙O2peak values in a large, population-based sample of schoolchildren from a large Latin-American city at high altitude. © 2016 The Authors American Journal of Human Biology Published by Wiley Periodicals, Inc.

  4. [The algorithm for the determination of the sufficient number of dynamic electroneurostimulation procedures based on the magnitude of individual testing voltage at the reference point].

    Science.gov (United States)

    Chernysh, I M; Zilov, V G; Vasilenko, A M; Frolkov, B K

    This article was designed to present evidence of the advantages of the personified approach to the treatment of the patients presenting with arterial hypertension (AH), lumbar spinal dorsopathy (LSD), chronic obstructive pulmonary disease (COPD), and duodenal ulcer (DU) at the stage of exacerbation obtained by the measurements of testing voltage at the reference point (Utest). The objective of the present study was to develop the algorithm for the determination of the sufficient number (optimal duration) of therapeutic procedures of the protracted treatment with the use of the Utest at the reference point. The study included 647 patients (439 women and 208 men at the age varying from 25 to 72 years) with grade I-II AH, DU at the stage of exacerbation, grades II and III lumbar spinal dorsopathy, grade II-III COPD. The informed written content to participate in the study was obtained from all the patients. They were divided into three groups. Those comprising group 1 were treated by standard therapy, patients of group 2 received the same treatment supplemented by dynamic electroneurostimulation (DENS) while the patients of the third group were given personified DENS in accordance with the determined sufficient number of DENS procedures. The blood pressure in the patients with AH comprising group 3 was found to decrease more significantly in comparison with those in groups 1 an 2 (by 9% and 3% respectively). The intensity of pain syndrome in the patients with lumbar spinal dorsopathy evaluated based on the visual analog scale decreased two-fold in group 3 in comparison with the 1.2 and 1.8 times decrease in groups 1 and 2 respectively. The level of pH in the stomach of patients with DU increased by 33.3% in group 3 in comparison with 12,5%, in group 1 and 21,8% in group 2. Vital capacity of the lungs in the patients of group 3 presenting with COPD and treated with the use of the personified approach was found to increase almost up to 612 ml in comparison with 477 ml

  5. Non-cancer morbidity among Estonian Chernobyl cleanup workers: a register-based cohort study.

    Science.gov (United States)

    Rahu, Kaja; Bromet, Evelyn J; Hakulinen, Timo; Auvinen, Anssi; Uusküla, Anneli; Rahu, Mati

    2014-05-14

    To examine non-cancer morbidity in the Estonian Chernobyl cleanup workers cohort compared with the population sample with special attention to radiation-related diseases and mental health disorders. Register-based cohort study. Estonia. An exposed cohort of 3680 men (cleanup workers) and an unexposed cohort of 7631 men (population sample) were followed from 2004 to 2012 through the Population Registry and Health Insurance Fund database. Morbidity in the exposed cohort compared with the unexposed controls was estimated in terms of rate ratio (RR) with 95% CIs using Poisson regression models. Elevated morbidity in the exposed cohort was found for diseases of the nervous system, digestive system, musculoskeletal system, ischaemic heart disease and for external causes. The most salient excess risk was observed for thyroid diseases (RR=1.69; 95% CI 1.38 to 2.07), intentional self-harm (RR=1.47; 95% CI 1.04 to 2.09) and selected alcohol-related diagnoses (RR=1.25; 95% CI 1.12 to 1.39). No increase in morbidity for stress reactions, depression, headaches or sleep disorders was detected. No obvious excess morbidity consistent with biological effects of radiation was seen in the exposed cohort, with the possible exception of benign thyroid diseases. Increased alcohol-induced morbidity may reflect alcohol abuse, and could underlie some of the higher morbidity rates. Mental disorders in the exposed cohort were probably under-reported. The future challenge will be to study mental and physical comorbidities in the Chernobyl cleanup workers cohort. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  6. Mixotrophy in Pyroleae (Ericaceae) from Estonian boreal forests does not vary with light or tissue age.

    Science.gov (United States)

    Lallemand, Félix; Puttsepp, Ülle; Lang, Mait; Luud, Aarne; Courty, Pierre-Emmanuel; Palancade, Cécile; Selosse, Marc-André

    2017-09-01

    In temperate forests, some green plants, namely pyroloids (Pyroleae, Ericaceae) and some orchids, independently evolved a mode of nutrition mixing photosynthates and carbon gained from their mycorrhizal fungi (mixotrophy). Fungal carbon is more enriched in 13C than photosynthates, allowing estimation of the proportion of carbon acquired heterotrophically from fungi in plant biomass. Based on 13C enrichment, mixotrophic orchids have previously been shown to increase shoot autotrophy level over the growth season and with environmental light availability. But little is known about the plasticity of use of photosynthetic versus fungal carbon in pyroloids. Plasticity of mixotrophy with leaf age or light level (estimated from canopy openness) was investigated in pyroloids from three Estonian boreal forests. Bulk leaf 13C enrichment of five pyroloid species was compared with that of control autotrophic plants along temporal series (over one growth season) and environmental light gradients (n=405 samples). Mixotrophic 13C enrichment was detected at studied sites for Pyrola chlorantha and Orthilia secunda (except at one site for the latter), but not for Chimaphila umbellata, Pyrola rotundifolia and Moneses uniflora. Enrichment with 13C did not vary over the growth season or between leaves from current and previous years. Finally, although one co-occurring mixotrophic orchid showed 13C depletion with increasing light availability, as expected for mixotrophs, all pyroloids responded identically to autotrophic control plants along light gradients. A phylogenetic trend previously observed is further supported: mixotrophy is rarely supported by 13C enrichment in the Chimaphila + Moneses clade, whereas it is frequent in the Pyrola + Orthilia clade. Moreover, pyroloid mixotrophy does not respond plastically to ageing or to light level. This contrasts with the usual view of a convergent evolution with orchids, and casts doubt on the way pyroloids use the carbon gained from their

  7. Personality traits and eating habits in a large sample of Estonians.

    Science.gov (United States)

    Mõttus, René; Realo, Anu; Allik, Jüri; Deary, Ian J; Esko, Tõnu; Metspalu, Andres

    2012-11-01

    Diet has health consequences, which makes knowing the psychological correlates of dietary habits important. Associations between dietary habits and personality traits were examined in a large sample of Estonians (N = 1,691) aged between 18 and 89 years. Dietary habits were measured using 11 items, which grouped into two factors reflecting (a) health aware and (b) traditional dietary patterns. The health aware diet factor was defined by eating more cereal and dairy products, fish, vegetables and fruits. The traditional diet factor was defined by eating more potatoes, meat and meat products, and bread. Personality was assessed by participants themselves and by people who knew them well. The questionnaire used was the NEO Personality Inventory-3, which measures the Five-Factor Model personality broad traits of Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness, along with six facets for each trait. Gender, age and educational level were controlled for. Higher scores on the health aware diet factor were associated with lower Neuroticism, and higher Extraversion, Openness and Conscientiousness (effect sizes were modest: r = .11 to 0.17 in self-ratings, and r = .08 to 0.11 in informant-ratings, ps < 0.01 or lower). Higher scores on the traditional diet factor were related to lower levels of Openness (r = -0.14 and -0.13, p < .001, self- and informant-ratings, respectively). Endorsement of healthy and avoidance of traditional dietary items are associated with people's personality trait levels, especially higher Openness. The results may inform dietary interventions with respect to possible barriers to diet change.

  8. Non-cancer morbidity among Estonian Chernobyl cleanup workers: a register-based cohort study

    Science.gov (United States)

    Rahu, Kaja; Bromet, Evelyn J; Hakulinen, Timo; Auvinen, Anssi; Uusküla, Anneli; Rahu, Mati

    2014-01-01

    Objective To examine non-cancer morbidity in the Estonian Chernobyl cleanup workers cohort compared with the population sample with special attention to radiation-related diseases and mental health disorders. Design Register-based cohort study. Setting Estonia. Participants An exposed cohort of 3680 men (cleanup workers) and an unexposed cohort of 7631 men (population sample) were followed from 2004 to 2012 through the Population Registry and Health Insurance Fund database. Methods Morbidity in the exposed cohort compared with the unexposed controls was estimated in terms of rate ratio (RR) with 95% CIs using Poisson regression models. Results Elevated morbidity in the exposed cohort was found for diseases of the nervous system, digestive system, musculoskeletal system, ischaemic heart disease and for external causes. The most salient excess risk was observed for thyroid diseases (RR=1.69; 95% CI 1.38 to 2.07), intentional self-harm (RR=1.47; 95% CI 1.04 to 2.09) and selected alcohol-related diagnoses (RR=1.25; 95% CI 1.12 to 1.39). No increase in morbidity for stress reactions, depression, headaches or sleep disorders was detected. Conclusions No obvious excess morbidity consistent with biological effects of radiation was seen in the exposed cohort, with the possible exception of benign thyroid diseases. Increased alcohol-induced morbidity may reflect alcohol abuse, and could underlie some of the higher morbidity rates. Mental disorders in the exposed cohort were probably under-reported. The future challenge will be to study mental and physical comorbidities in the Chernobyl cleanup workers cohort. PMID:24833681

  9. Prevalence of enteropathogenic Yersinia in Estonian, Latvian, and Russian (Leningrad region) pigs.

    Science.gov (United States)

    Martínez, Pilar Ortiz; Fredriksson-Ahomaa, Maria; Sokolova, Yulia; Roasto, Mati; Berzins, Aivars; Korkeala, Hannu

    2009-01-01

    Tonsils of 457 fattening pigs from Estonia (n = 151), Latvia (n = 109), and the Leningrad Region of Russia (n = 197) were collected between 2004 and 2007 to study the prevalence of enteropathogenic Yersinia in slaughter pigs. Yersinia enterocolitica and Yersinia pseudotuberculosis were isolated by selective and cold enrichment. Pathogenic Y. enterocolitica and Y. pseudotuberculosis were identified by PCR targeting the chromosomal genes ail and inv, respectively. The presence of the virulence plasmid was confirmed by PCR targeting the virF gene of Y. enterocolitica and Y. pseudotuberculosis. The prevalence of ail-positive Y. enterocolitica was 89% in Estonia, 64% in Latvia, and 34% in Russia, with 81% of ail-positive samples being virF-positive. A statistically significant (p Estonian and Latvian pigs and between pigs from Latvia and the Leningrad Region of Russia was observed when assuming randomized sampling. Y. enterocolitica bioserotype 4/O:3 was the only pathogenic type found. The prevalence of inv and virF-positive Y. pseudotuberculosis was higher in Russia (7%) than in Latvia (5%) and Estonia (1%), with a statistically significant difference between pigs from Estonia and the Leningrad Region of Russia when assuming both randomized sampling and clustering at farms. All Y. pseudotuberculosis isolates were bioserotype 2/O:3. A total of eight pigs (2%), one pig from Latvia and seven pigs from the Leningrad Region of Russia, carried both pathogenic Y. enterocolitica and Y. pseudotuberculosis in the tonsils. Cold enrichment was found to be a more efficient method compared to selective enrichment to isolate both species. Pigs seem to be an important reservoir of human enteropathogenic Y. enterocolitica 4/O:3 and Y. pseudotuberculosis 2/O:3 in these countries.

  10. Occurrence of clinical mastitis in primiparous Estonian dairy cows in different housing conditions

    Directory of Open Access Journals (Sweden)

    Aasmäe Birgit

    2006-11-01

    Full Text Available Abstract Background Objectives of the study were to document the impact of some management factors on the occurrence of clinical mastitis in primiparous dairy cows and to identify common udder pathogens of clinical mastitis in freshly calved heifers and multiparous cows on the day of calving. Methods A one-year study was conducted during 2004 and 2005 in 11 selected Estonian dairy herds. Data consisted of 68 heifers with clinical mastitis and 995 heifers without clinical mastitis on the day of calving. Multivariable logistic regression with a random herd effect was used to investigate any association between housing system or the time interval from movement of heifers to the calving facility and day of calving on occurrence of clinical mastitis. Milk samples for bacteriological analysis were collected from affected heifers and multiparous cows on the day of calving Results Clinical mastitis occurrence in the study population of freshly calved heifers equalled 6.1 %. Housing system was not a significant risk factor for clinical mastitis of freshly calved heifers. Moving heifers to the cowbarn less than two weeks before calving in tiestall farms increased risk (OR = 5.9 p = 0.001 for clinical mastitis at parturition. The most frequently isolated udder pathogens among heifers were Escherichia coli (22.1%, Streptococcus uberis (19.1% and coagulase-negative staphylococci (8.8%. In comparison, the main pathogen in multiparous cows with clinical mastitis at parturition was Staphylococcus aureus (11.2%. Conclusion Moving heifers to the calving facilities too late in tiestall farms increased risk for clinical mastitis at parturition. The isolated udder pathogens did not differ significantly in tiestall farms compared to freestall farms in heifers, but differences were found between heifers and multiparous cows at parturition.

  11. Prevalence of alcohol-related pathologies at autopsy: Estonian Forensic Study of Alcohol and Premature Death.

    Science.gov (United States)

    Tuusov, Jana; Lang, Katrin; Väli, Marika; Pärna, Kersti; Tõnisson, Mailis; Ringmets, Inge; McKee, Martin; Helander, Anders; Leon, David A

    2014-12-01

    Alcohol can induce diverse serious pathologies, yet this complexity may be obscured when alcohol-related deaths are classified according to a single underlying cause. We sought to quantify this issue and its implications for analysing mortality data. Cross-sectional study included 554 men aged 25-54 in Estonia undergoing forensic autopsy in 2008-09. Potentially alcohol-related pathologies were identified following macroscopic and histological examination. Alcohol biomarkers levels were determined. For a subset (26%), drinking behaviour was provided by next-of-kin. The Estonian Statistics Office provided underlying cause of death. Most deaths (75%) showed evidence of potentially alcohol-related pathologies, and 32% had pathologies in two or more organs. The liver was most commonly affected [60.5%, 95% confidence interval (CI) = 56.3-64.6] followed by the lungs (18.6%, 95% CI = 15.4-22.1), stomach (17.5%, 95% CI = 14.4-20.9), pancreas (14.1%, 95% CI = 11.3-17.3), heart (4.9%, 95% CI = 3.2-7.0) and oesophagus (1.4%, 95% CI = 0.6-2.8). Only a minority with liver pathology had a second pathology. The number of pathologies correlated with alcohol biomarkers (phosphatidylethanol, gamma-glytamyl transpeptidase in blood, ethylglucuronide, ethylsulphate in urine). Despite the high prevalence of liver pathology, few deaths had alcoholic liver disease specified as the underlying cause. The majority of 554 men aged 25-54 undergoing forensic autopsy in Estonia in 2008-09 showed evidence of alcohol-related pathology. However, the recording of deaths by underlying cause failed to capture the scale and nature of alcohol-induced pathologies found. © 2014 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

  12. Reference intervals and discrimination values of the Lanthony desaturated D-15 panel test in young to middle-aged Japanese army officials: the Okubo Color Study Report 1.

    Science.gov (United States)

    Shoji, T; Sakurai, Y; Chihara, E; Nishikawa, S; Omae, K

    2009-06-01

    To better understand the reference values and adequate discrimination values of colour vision function with described quantitative systems for the Lanthony desaturated D-15 panel (D-15DS). A total of 1042 Japanese male officials were interviewed and underwent testing using Ishihara pseudoisochromatic plates, standard pseudoisochromatic plates part 2, and the D-15DS. The Farnsworth-Munsell (F-M) 100-hue test and the criteria of Verriest et al were used as definitive tests. Outcomes of the D-15DS were calculated using Bowman's Colour Confusion Index (CCI). The study design included two criteria. In criterion A, subjects with current or past ocular disease and a best-corrected visual acuity less than 0.7 on a decimal visual acuity chart were excluded. In criterion B, among subjects who satisfied criterion A, those who had a congenital colour sense anomaly were excluded. Overall, the 90th percentile (95th percentile) CCI values for criteria A and B in the worse eye were 1.70 (1.95) and 1.59 (1.73), respectively. In subjects satisfying criterion B, the area under the receiver operating characteristic curve was 0.951 (95% confidence interval, 0.931-0.971). The CCI discrimination values of 1.52 or 1.63 showed 90.3% sensitivity and 90% specificity, or 71.5% sensitivity and 95% specificity, respectively, for discriminating acquired colour vision impairment (ACVI). We provided the 90th and 95th percentiles in a young to middle-aged healthy population. The CCI is in good agreement with the diagnosis of ACVI. Our results could be helpful for using D-15DS for screening purposes.

  13. RAI1 Alternate Probe Identifies Additional Breast Cancer Cases as Amplified Following Equivocal HER2 Fluorescence In Situ Hybridization Testing: Experience From a National Reference Laboratory.

    Science.gov (United States)

    Hui, Ling; Geiersbach, Katherine B; Downs-Kelly, Erinn; Gulbahce, H Evin

    2017-02-01

    -In 2013 the American Society of Clinical Oncology and College of American Pathologists updated the HER2 guidelines and changed the equivocal category for HER2 in situ hybridization testing to an average HER2 copy number of 4.0 to 5.9 with a HER2:CEP17 ratio of less than 2.0 and proposed retesting, with an option of using another control probe to avoid false-negative results. RAI1, located at band position 17p11.2, is a popular alternate probe locus for retesting equivocal changes. -To review experience with the RAI1 alternate probe in HER2 fluorescence in situ hybridization equivocal breast cancers. -Primary and metastatic breast cancers with equivocal HER2 fluorescence in situ hybridization, retested with an alternate (RAI1) probe, were identified. HER2, RAI1, and CEP17 copy numbers, HER2 to control probe ratios, and genetic heterogeneity were recorded. Hematoxylin-eosin-stained slides were reviewed for type and grade of cancer. -Of 876 cases tested with CEP17 as the reference probe, 97 (11.1%) had equivocal HER2 fluorescence in situ hybridization results. Additional testing with the RAI1 probe classified 39.2% cases (38 of 97) as amplified with a HER2:RAI1 ratio ranging from 2.0 to 3.2 (mean, 2.37); 3.1% (3 of 97) were still unclassifiable because of a deletion of RAI1. -RAI1 identified close to 40% of original HER2 fluorescence in situ hybridization equivocal cases as amplified, making these patients eligible for targeted therapies. It is not known whether guidelines for US Food and Drug Administration-approved probes can be extrapolated to alternate probes when an alternate control probe shows losses or gains. Because of the lack of guidelines for reporting HER2 status with alternate probes, laboratories face challenges in interpreting results.

  14. The Role of Parents and Parental Mediation on 0-3-Year Olds' Digital Play with Smart Devices: Estonian Parents' Attitudes and Practices

    Science.gov (United States)

    Nevski, Elyna; Siibak, Andra

    2016-01-01

    In this manuscript, we analyse the attitudes and practices of Estonian parents (N = 198) who allowed their 0-3-year olds to use smart devices. We aimed to discover if there was an interaction between parental use of smart technologies, parents' attitudes and the child's age that would predict young children's usage of smart devices. We also wanted…

  15. Economic modelling of the capture-transport-sink scenario of industrial CO2 emissions: The Estonian-Latvian cross-border case study

    NARCIS (Netherlands)

    Shogenova, A.; Shogenov, K.; Pomeranceva, R.; Nulle, I.; Neele, F.; Hendriks, C.

    2011-01-01

    Industrial CO2 emissions and opportunities for CO2 geological storage in the Baltic Region were studied within the EU GeoCapacity project supported by the European Union Framework Programme 6. Estonia produces the largest amounts of CO2 emissions in the region, due to the combustion of Estonian oil

  16. Attitudes of Academic Staff towards Their Own Work and towards External Evaluation, from the Perspective of Self-Determination Theory: Estonian Case

    Science.gov (United States)

    Seema, Riin; Udam, Maiki; Mattisen, Heli

    2016-01-01

    The purpose of this study was to ascertain the attitudes of academic staff towards their own work as well as towards external evaluations. The study was based on (1) an analysis of assessment reports of institutional accreditations conducted by the Estonian Quality Agency for Higher and Vocational Education and (2) self-determination theory on…

  17. “... if there’s a party, then there’s definitely alcohol”. Construction of partying practices and abstinence in Estonian youth forums

    Directory of Open Access Journals (Sweden)

    Parder Mari-Liisa

    2015-12-01

    Full Text Available AIMS – Adolescents’ abstinence from alcohol has not been much researched in terms of providing suggestions for prevention strategies. This study aims to fill that gap by offering a practice theory-inspired analysis of how the unwritten rules of partying practices are communicated between posters of Estonian youth forums.

  18. A Silent Finn, a Silent Finno-Ugric, or a Silent Nordic? A Comparative Study of Estonian, Finnish, and Swedish Mother-Adolescent Interactions.

    Science.gov (United States)

    Tulviste, Tiia; Mizera, Luule; de Geer, Boel; Tryggvason, Marja-Terttu

    2003-01-01

    Compared verbal characteristics of family interaction in the stereotypically tongue-tied Nordic region of the Western world. Compared mothers' and early adolescents' talkativeness and monologuing and mothers' conversational dominance emerging in real-life video recordings in Estonian, Finnish, and Swedish monolingual and bilingual families. (VWL)

  19. Health-related quality of life of Estonian adolescents: reliability and validity of the PedsQL™ 4.0 Generic Core Scales in Estonia.

    Science.gov (United States)

    Viira, Roomet; Koka, Andre

    2011-07-01

    The main aim of this study was to examine the reliability and validity of the Pediatric Quality of Life Inventory™ 4.0 (PedsQL™ 4.0) Generic Core Scales among Estonian adolescents. Gender differences in health-related quality of life (HRQoL) were also investigated. The 654 adolescents (309 boys and 345 girls) aged 13-14 years (M age = 13.57 years, SD = 0.62) completed Estonian version of the PedsQL™ 4.0. Results of the confirmatory factor analysis for a five-factor model of the Estonian version of PedsQL™ 4.0 approached the criteria of acceptable fit after setting error covariance to be free between some of the items within physical health, emotional functioning and social functioning subscales. Cronbach's alpha coefficients exceeded the minimum criterion of 0.70 for all subscales except for days missed from school because of illness subscale. With regard to gender differences, consistent with previous studies, girls reported lower level on total score of HRQoL as well as its aspects of physical health, emotional functioning and psychosocial health. The present study revealed that after some modifications, the PedsQL™ 4.0 could be considered as suitable instrument to measure HRQoL among Estonian adolescents. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

  20. Corporate Governance from the Perspective of Stakeholder Theory and in Light of Perceptions among Estonian Owners and Managers of Relations with Stakeholders / Mari Kooskora

    Index Scriptorium Estoniae

    Kooskora, Mari, 1969-

    2006-01-01

    Äriühingute valitsemise kontseptsioon ja teoreetiline taust; Eesti omanike ja tippjuhtide ootused suhetes erinevate huvigruppidega ning äriühingute valitsemine huvigruppide teooriast lähtudes. Skeem: The stakeholder model. Tabelid: Contractual and community stakeholders; Overview of how perceptions of the main stakeholder groups among Estonian business leaders between 1995-2004 have changed

  1. Characterisation of Estonian Kukersite by spectroscopy and pyrolysis: Evidence for abundant alkyl phenolic moieties in an Ordovician, marine, Type II/I kerogen

    NARCIS (Netherlands)

    Sinninghe Damsté, J.S.; Derenne, S.; Largeau, C.; Casadevall, E.; Tegelaar, E.W.

    1990-01-01

    The kerogen of a sample of Estonian Kukersite (Ordovician) was examined by spectroscopic (solid state 13C NMR, FTIR) and pyrolytic ('off-line', flash) methods. This revealed an important contribution of long, linear alkyl chains in Kukersite kerogen. The hydrocarbons formed upon pyrolysis are

  2. Euroopa-ihalusest taasiseseisvusperioodi autobiograafiates / European Identifications in Post-Soviet Estonian Life Writing

    Directory of Open Access Journals (Sweden)

    Leena Kurvet-Käosaar

    2016-12-01

    Full Text Available Teesid: Artikkel käsitleb Euroopat kui identiteedi ja minaduse sõlmpunkti ja enesevahenduse mõõdet kolmes omaelulookirjutuslikus teoses, mille autoritel on väljapaistev positsioon eesti (kirjanduskultuuris: Jaan Krossi „Kallid kaasteelised“ (2003a, 2008, Jaan Kaplinski „Isale“ (2003 ja Tõnu Õnnepalu „Flandria päevik“ (2007. Artikkel keskendub sellele, kuidas küsimused suhestumise trajektooridest Euroopa mäluruumiga haakuvad Krossi, Kaplinski ja Õnnepalu teostes esiletuleva enesemääratlusliku raamiga, neist lähtuvate vastastikuse kõnetuse võimaluste ja oma aegruumi tunnetuse pidepunktidega. Kuigi tegemist on eesti keeles ilmunud ning eesti kultuuriruumi lugejale suunatud teostega, seostuvad neis väljajoonistuvad enesemääratluse teljed viimastel aastakümnetel hoogustunud laiemate aruteludega ühtse Euroopa mäluraami ning identiteedi võimalikkusest ja selle toimimise tingimustest.   In recent years, the question of the possibility of a shared frame of memory and identity in Europe, its desired manifestations and practices for attaining it as well as its obstacles and limitations to it have gained prominence in scholarly debates in a number of disciplines. In terms of the division between the East and West of Europe, these discussions take as their starting point the collapse of the Soviet system in 1989 as well as the European Union enlargement in 2004. Far from uniform, the exceedingly complex and contrasting ranges of arguments have put forward a varied palette of perspectives and suggestions about possible and desirable implications of Europe in different socio-political and cultural configurations. Taking these debates as my starting point, the current article offers an analysis of three life writing works by contemporary Estonian authors and intellectuals, Kallid kaasteelised (Dear Fellow Travellers, 2003, 2008 by Jaan Kross, Isale (To My Father, 2003 by Jaan Kaplinski and Flandria päevik (The Flemish Diary

  3. References: BSCW

    Data.gov (United States)

    National Aeronautics and Space Administration — Benchmark Supercritical Wing was also tested on the OTT with oscillations in Pitch. Only one row of pressure transducers were acquired during these tests. The time...

  4. Valores de referência para o teste cardiopulmonar para homens e mulheres sedentários e ativos Valores de referencia para el test cardiopulmonar para hombres y mujeres sedentarios y activos Reference values for cardiopulmonary exercise testing for sedentary and active men and women

    Directory of Open Access Journals (Sweden)

    Artur Haddad Herdy

    2011-01-01

    Full Text Available FUNDAMENTO: Os valores de referência de teste cardiopulmonar (TCP disponíveis no Brasil foram derivados de cicloergômetro, em população sedentária e relativamente pequena. OBJETIVO: Fornecer valores de referência para o TCP em brasileiros de ambos os sexos, sedentários e ativos. MÉTODOS: ENtre 2006 e 2008, 3.992 TCP de indivíduos saudáveis foram selecionados de nosso laboratório. Atletas, fumantes, portadores de qualquer patologia conhecida, usuários de medicação contínua e obesos foram excluídos. VO2 pico foi considerado VO2 máx. Analisamos também VO2 de limiar anaeróbico, ventilação máxima e pulso de oxigênio de acordo com sexo, faixa etária, sedentários e ativos. As faixas etárias foram assim divididas: G1 (15-24 anos, G2 (25-34, G3 (35-44, G4 (45-54, G5 (55-64 e G6 (65-74. RESULTADOS: De acordo com as faixas etárias, os valores médios de VO2 em ml/kg/min com os respectivos desvios-padrão foram: Homem ativo: G1-50,6 ± 7,3; G2-47,4 ± 7,4; G3-45,4 ± 6,8; G4-40,5 ± 6,5; G5-35,3 ± 6,2; G6-30,0 ± 6,1. Mulher ativa: G1-38,9 ± 5,7; G2-38,1 ± 6,6; G3-34,9 ± 5,9; G4-31,1 ± 5,4; G5-28,6 ± 6,1; G6-25,1 ± 4,4. Homem sedentário: G1-47,4 ± 7,9; G2-41,9 ± 7,2; G3-39,0 ± 6,8; G4-35,6 ± 7,7; G5-30,0 ± 6,3; G6-23,1 ± 6,3. Mulher sedentária: G1-35,6 ± 5,7; G2-34,0 ± 4,8; G3-30,0 ± 5,4; G4-27,2 ± 5,0; G5-23,9 ± 4,2; G6-21,2 ± 3,4. CONCLUSÃO: ESte artigo fornece valores de referência de VO2 máx, entre outros parâmetros, no Teste Cardiopulmonar realizados na esteira ergométrica em indivíduos de ambos os sexos, ativos e sedentários.FUNDAMENTO: Los valores de referencia de test cardiopulmonar (TCP disponibles en el Brasil fueron derivados de ciclóergómetro, en población sedentaria y relativamente pequeña. OBJETIVO: Proveer valores de referencia para el TCP en brasileños de ambos sexos, sedentarios y activos. MÉTODOS: Entre 2006 y 2008, 3.992 TCP de individuos sanos fueron seleccionados de nuestro

  5. In vitro genotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment.

    Science.gov (United States)

    El Yamani, Naouale; Collins, Andrew R; Rundén-Pran, Elise; Fjellsbø, Lise Marie; Shaposhnikov, Sergey; Zienolddiny, Shanbeh; Dusinska, Maria

    2017-01-01

    There is serious concern about the potential harmful effects of certain nanomaterials (NMs), on account of their ability to penetrate cell membranes and the increased reactivity that results from their increased surface area compared with bulk chemicals. To assess the safety of NMs, reliable tests are needed. We have investigated the possible genotoxicity of four representative NMs, derived from titanium dioxide, zinc oxide, cerium oxide and silver, in two human cell lines, A549 alveolar epithelial cells and lymphoblastoid TK6 cells. A high-throughput version of the comet assay was used to measure DNA strand beaks (SBs) as well as oxidised purines (converted to breaks with the enzyme formamidopyrimidine DNA glycosylase). In parallel, cytotoxicity was measured with the alamarBlue® assay, and the ability of NM-treated cells to survive was assessed by their colony-forming efficiency. TiO2 and CeO2 NMs were only slightly cytotoxic by the alamarBlue® test, and had no long-term effect on colony-forming efficiency. However, both induced DNA damage at non-cytotoxic concentrations; the damage decreased from 3 to 24-h exposure, except in the case of CeO2-treated A549 cells. ZnO and Ag NMs affected cell survival, and induced high levels of DNA damage at cytotoxic concentrations. At lower concentrations, there was significant damage, which tended to persist over 24 h. The implication is that all four reference metal NMs tested-whether cytotoxic or not-are genotoxic. A full assessment of NM toxicity should include tests on different cell types, different times of incubation and a wide range of (especially non-cytotoxic) concentrations; a test for cell viability should be performed in parallel. Inclusion of Fpg in the comet assay allows detection of indirect genotoxic effects via oxidative stress. © The Author 2016. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Two Decades of Estonian Police and the (Irrelevance of Police Models for the Development of Safety Policy

    Directory of Open Access Journals (Sweden)

    Priit Suve

    2016-07-01

    Full Text Available Police models are designed to improve safety in society. Although Estonia has not deliberately used any (combination of police models for developing its policies of safety and its police reforms since the country regained independence, its safety has improved considerably during the last couple of decades. The scholarly discussions about police models are overwhelmingly about the possible effects of different models on safety management and about their application to particular countries. However, countries like Estonia with no consistent conceptions of police have received little attention in academic literature. We aim to fill this gap by analysing the developments of the Estonian police in its philosophical, strategic, tactical and organisational dimensions over the period between 1991 and 2013. The analysed materials include the official police development plans, legislation, statutes, training programs and statistics about the police. Our analysis shows that although safety in Estonia has improved considerably, developments of the Estonian police are characterised by internal discrepancies and inconsistencies. In view of this, we put forth some hypotheses for further studies regarding policy development in a situation where policy is not explicitly stated or where organisational reforms are seen not as “simple” or “complex” problems, but as “wicked” problems.

  7. Diversity of Helicobacter pylori genotypes among Estonian and Russian patients with perforated peptic ulcer, living in Southern Estonia.

    Science.gov (United States)

    Sillakivi, T; Aro, H; Ustav, M; Peetsalu, M; Peetsalu, A; Mikelsaar, M

    2001-02-05

    To compare the genomic variation of Helicobacter pylori in samples obtained from patients with perforated peptic ulcer, living in the same area of Estonia but belonging to different nationalities, 50 non-consecutive patients (32 Estonians and 18 Russians) admitted in the Tartu University Hospital in 1997-1999 were studied. Gastric samples of antral mucosa were obtained during operation and analysed histologically and with PCR for detection of different genotypes of H. pylori (cagA and vacA s and m subtypes). Among the 50 perforated peptic ulcer patients with histologically proven H. pylori colonisation no sample of gastric mucosa showed the s1b subtype of the vacA gene. The perforated peptic ulcer patients were mainly infected with cagA (82%) and s1 (98%) genotypes of H. pylori. The distribution of s1a/m1, s1a/m2 and s2/m2 subtypes of vacA genes was statistically different in Estonian and Russian patients (PEstonian and Russian patients with perforated peptic ulcer from Southern Estonia.

  8. Isamaalaulud ja okupatsioonirežiim – nostalgia, utoopia ja reaalsus. Estonian Patriotic Songs and the Occupational Regime – Nostalgia, Utopia and Reality

    Directory of Open Access Journals (Sweden)

    Kanni Labi

    2012-04-01

    Full Text Available Estonian knowledge of history emanates from the fact that constituting an independent nation has for the most part been nothing but a utopia, and was a reality for a relatively short time. When it comes to selfidentification though, the expression ’a singing people’ is often used by the Estonians to describe themselves. Nostalgia for freedom is reflected in the Estonian culture of almost all periods and is carried on by the singing tradition, where patriotic songs emerge independent of different musical tastes within a particular generation and form an important part of a common Estonian repertoire. Patriotic songs occupy a central place in several fields of Estonian culture: besides music culture also in popular culture,and literary history – the works of poetry which have gained the most popularity are those which when put to music have been the most widely spread among the people. The main part of the most popular Estonian patriotic songs are choral songs from the national awakening at the end of the 19th century. Despite the national programmes aiming to wipe out ‘bourgeois nationalism’, they were sung at the song festivals in the Soviet era and were published in song books, expressing the people’s nostalgia for freedom lost. After the end of the Second World War, there was an attempt at launching a kind of patriotic new creation, where patriotism was merged with Soviet pathos; the aim was to show that the people’s utopia was in fact communism, but not a single one of those songs made it into the people’s common repertoire. Only the patriotic songs composed in the 1980s during the so-called new national awakening reached a popularity comparable to that of the old songs. The discourse on ’Estonianness’ and the shaping of a matching repertoire under imperial Russian rule took place under very different circumstances than its preservation and development in the second half of the 20th century under Soviet occupation, but

  9. Use of a national database as a tool to identify primary medication non-adherence: The Estonian ePrescription system.

    Science.gov (United States)

    Laius, Ott; Pisarev, Heti; Volmer, Daisy; Kõks, Sulev; Märtson, Aare; Maasalu, Katre

    2017-10-05

    Medication adherence can be divided into primary and secondary adherence. Primary medication non-adherence (PMN) occurs when a patient does not obtain medicine with their initial prescription. Secondary non-adherence measures prescription refills among patients who previously filled their first prescription. While secondary non-adherence has been studied thoroughly, PMN has been assessed less extensively, due to lack of available data. Estonian ePrescription system might prove a valuable tool for this. The aim of this study was to evaluate PMN and the interval between prescribing and dispensing of medicines using the Estonian ePrescriptions database to establish its potential use for this purpose and for other qualitative drug utilization research measures. Osteoporosis medicines were used as an example. The Estonian Prescription Centre was used to evaluate if patients purchase medicines after initial prescription of osteoporosis medicine. Prescriptions from 2012 to 2015 of all patients over 18 were included. PMN was defined as the first prescription not being dispensed before it expired (60 days). The rate of PMN was calculated. Estonian ePrescription System enabled fast evaluation of PMN of osteoporosis patients based on data about prescribing, dispensing and time intervals in-between. Of patients who started osteoporosis treatment 13.1% were primary non-adherent. Of primary non-adherent patients 42% still started treatment at some point during the study. Of patients who did purchase their first prescription 80.4% did so within a week and 95% within 25 days. The Estonian ePrescription system is a useful tool for monitoring PMN. The PMN of osteoporosis medicines was identified as lower than previously reported. More similar type of studies about other groups of medicines would be needed to understand the pattern of PMN and give valuable information to healthcare specialists about how to increase initiation of treatment. Copyright © 2017 Elsevier Inc. All rights

  10. Reappraisal of Leishmanin Skin Test (LST) in the management of American Cutaneous Leishmaniasis: A retrospective analysis from a reference center in Argentina.

    Science.gov (United States)

    Krolewiecki, Alejandro Javier; Almazan, Maria Cristina; Quipildor, Marcelo; Juarez, Marisa; Gil, Jose Fernando; Espinosa, Marco; Canabire, Maria; Cajal, Silvana Pamela

    2017-10-01

    Leishmania (Viannia) braziliensis is the species most frequently implicated with cutaneous and mucosal leishmaniasis in the Americas; its diagnosis is based on the identification of amastigotes in lesions, which is limited by low parasite burden. Leishmanin Skin Test (LST) is a support tool for diagnosis, based on delayed type hypersensitivity responses to Leishmania antigens injected intradermally, used in endemic areas as a complement to diagnosis. A retrospective analysis of individuals evaluated for their first episode of tegumentary leishmaniasis at a reference center in Argentina during the period 2006-2015 was performed, with the goal of assessing its usefulness as a support tool in the diagnosis of leishmaniasis. Demographic, clinical and diagnostic work-up were analyzed in individuals with clinically compatible lesions, lesion`s smear and LST. A total of 733 cases that met the case definition were included in the analysis; 678 (93%) localized cutaneous cases, 50 (7%) with mucosal involvement and 5 (high. Standardization of this technique and further research into its most adequate preparation and utilization protocols across different sites will help in the management of suspicious clinical cases.

  11. Evaluation of RAD51C as cancer susceptibility gene in a large breast-ovarian cancer patient population referred for genetic testing.

    Science.gov (United States)

    De Leeneer, K; Van Bockstal, M; De Brouwer, S; Swietek, N; Schietecatte, P; Sabbaghian, N; Van den Ende, J; Willocx, S; Storm, K; Blaumeiser, B; Van Asperen, C J; Wijnen, J T; Leunen, K; Legius, E; Michils, G; Matthijs, G; Blok, M J; Gomez-Garcia, E; De Paepe, A; Tischkowitz, M; Poppe, B; Claes, K

    2012-05-01

    Despite extensive analysis of the BRCA1 and BRCA2 genes, germline mutations are detected in <20% of families with a presumed genetic predisposition for breast and ovarian cancer. Recent literature reported RAD51C as a new breast cancer susceptibility gene. In this study, we report the analysis of 410 patients from 351 unrelated pedigrees. All were referred for genetic testing and we selected families with at least one reported case of ovarian cancer in which BRCA1&2 mutations were previously ruled out. We analyzed the coding exons, intron-exons boundaries, and UTRs of RAD51C. Our mutation analysis did not reveal any unequivocal deleterious mutation. In total 12 unique sequence variations were identified of which two were novel. Our study and others suggest a low prevalence of RAD51C mutations with an exception for some founder populations. This observation is in favor of the rare allele hypothesis in the debate over the nature of the genetic contribution to individual susceptibility to breast and ovarian cancer and further genome-wide studies in high risk families are warranted.

  12. Collaborative study to establish World Health Organization international reference reagents for dengue virus Types 1 to 4 RNA for use in nucleic acid testing.

    Science.gov (United States)

    Añez, Germán; Volkova, Evgeniya; Jiang, Zhen; Heisey, Daniel A R; Chancey, Caren; Fares, Rafaelle C G; Rios, Maria

    2017-08-01

    Dengue is the most important reemerging mosquito-borne viral disease worldwide. Caused by dengue virus (DENV), a member of the genus Flavivirus in the Flaviviridae family, dengue can be asymptomatic (approx. 80% of cases) or symptomatic, ranging from a flu-like illness known as dengue fever, to a life-threatening form called severe dengue. DENV is primarily transmitted from human to human through the bite of mosquitoes of the genus Aedes; however, it is also transmissible by transfusion of blood and blood components and by solid organ transplant. Nucleic acid test (NAT) assays are considered the most appropriate approach for blood donor screening for recent DENV infections, but there is no Food and Drug Administration-approved assay for the screening of blood for DENV. An international collaborative study was conducted to assess the suitability of reference reagent (RR) candidates for DENV Types 1 to 4 RNA for use in NAT-based assays. Two sets of RR candidates were prepared for each DENV type, one liquid frozen (Set 1) and one lyophilized (Set 2). A total of 28 laboratories from 20 countries agreed to participate in the study, of which 21 submitted the results for qualitative and/or quantitative assessments. The World Health Organization has established the lyophilized materials as international RRs for DENV RNA with a unitage of 13,500, 69,200, 23,400, and 33,900 units/mL for DENV-1 to -4, respectively. © 2017 AABB.

  13. Effects of achievement differences for internal/external frame of reference model investigations: A test of robustness of findings over diverse student samples.

    Science.gov (United States)

    Schmidt, Isabelle; Brunner, Martin; Preckel, Franzis

    2017-11-12

    Achievement in math and achievement in verbal school subjects are more strongly correlated than the respective academic self-concepts. The internal/external frame of reference model (I/E model; Marsh, 1986, Am. Educ. Res. J., 23, 129) explains this finding by social and dimensional comparison processes. We investigated a key assumption of the model that dimensional comparisons mainly depend on the difference in achievement between subjects. We compared correlations between subject-specific self-concepts of groups of elementary and secondary school students with or without achievement differences in the respective subjects. The main goals were (1) to show that effects of dimensional comparisons depend to a large degree on the existence of achievement differences between subjects, (2) to demonstrate the generalizability of findings over different grade levels and self-concept scales, and (3) to test a rarely used correlation comparison approach (CCA) for the investigation of I/E model assumptions. We analysed eight German elementary and secondary school student samples (grades 3-8) from three independent studies (Ns 326-878). Correlations between math and German self-concepts of students with identical grades in the respective subjects were compared with the correlation of self-concepts of students having different grades using Fisher's Z test for independent samples. In all samples, correlations between math self-concept and German self-concept were higher for students having identical grades than for students having different grades. Differences in median correlations had small effect sizes for elementary school students and moderate effect sizes for secondary school students. Findings generalized over grades and indicated a developmental aspect in self-concept formation. The CCA complements investigations within I/E-research. © 2017 The British Psychological Society.

  14. Eesti autobiograafilise kirjutuse kujunemisest 18. sajandist Teise maailmasõjani. The Development of Estonian Autobiographical Writing from the 18th Century to the Second World War

    Directory of Open Access Journals (Sweden)

    Rutt Hinrikus

    2012-04-01

    Full Text Available In this article I examine the development of Estonian autobiographical writing from its first manifestations to published memoirs, and the development of life writing and its diversification. The beginnings of life writing can be traced back to Estonian folk song and Estonian incidental poetry. The Moravian Brethren movement in Estonia in the 18th century promoted the spread of canonical autobiography. The Moravian Brethren offered alternative opportunities for self-realisation for Estonians who were serfs, and were therefore popular with the people. The practice of the Moravian Brethren made use of retelling and writing about the life of the congregation members, which sometimes became suitable biographies in print, especially stories of awakening. Several manuscript biographies have survived from the Brethren times, such as the biographies of Mäletu Jaan and Mihkel Sarapuu. In addition to the history of the Moravian Brethren movement, these biographies give information about the educational situation and living conditions of the people of the time. The Estonian life writing tradition emerged within the reigning Baltic German cultural space thanks to the Estophiles among the Baltic Germans (J. H. Rosenplänter and the first Estonian men of letters; from the early 19th century we have the diary by Rosenplänter, an estophile pastor from Pärnu, and the diary by the Estonian poet, the then-student Kristjan Jaak Peterson, both in the Estonian language. Johann Voldemar Jannsen, the founder of Estonian-language journalism, kept a diary in the German language for a longer period of time; it was usual that the first Estonian intellectuals (Lilli Suburg, and others in the late 19th century wrote in German. Admittedly, the first Estonian-language life history was written by a forward-looking 19th century peasant named Märt Mitt (1833-1912, who was conscious of himself as a historical subject and gave his memoirs, begun in the 1880s, a memorable title

  15. Riik võib lüüa SAS-i esmaspäevaks Estonian Airi omanikeringist välja / Erik Müürsepp, Mikk Salu

    Index Scriptorium Estoniae

    Müürsepp, Erik

    2008-01-01

    SAS osaleb Estonian Airþile lisakapitali eraldamises ainult juhul, kui Eesti riik müüb oma osaluses lennukompaniis SAS-ile. Peaminister Andrus Ansipi ning majandus- ja kommunikatsiooniminister Juhan Partsi seisukoht

  16. Postmodernistlikke jooni eesti noore režissuuri lavastustes 1969–1975 / Postmodernist Traits in the Performances of Young Estonian Directors 1969-1975

    Directory of Open Access Journals (Sweden)

    Rein Heinsalu

    2015-06-01

    Full Text Available Teesid: 1960. aastate lõpus toimusid eesti teatris suured muutused. Ilmus nähtus, mida hakati nimetama nooreks režissuuriks. Eeskätt on see seotud Evald Hermaküla, Jaan Toominga, Kalju Komissarovi, Kaarin Raidi jt nimedega. Noor režissuur tõstis mässu ahtaks muutunud realismi raamide vastu, mis ei vastanud noore põlvkonna teatriootustele. Olles mõjutatud ideeliselt radikaalsest eksperimentaalteatrist USAs, aga ka Jerzy Grotowski katsetustest ning teistest avangardsetest liikumistest, muutis see füüsilist teatrikeelt. Tõusis improvisatsiooni osakaal. Teater lakkas olemast dramaturgiliste tekstide esituskoht, vaid hakkas otsima etendustes vahetut kohalolu. Tajuprotsessi hakkas juhtima mängu põhimõte. Suured müüdid dekonstrueeriti, autoritaarsusele vastanduti. Seksuaalsus ilmutas end uuel jõul, toetatud alateadvuse impulssidest. Uue laine radikaalsus kestis 1970. aastate lõpuni, mil see sulandus peavoolu. Murrang teatriesteetikas mõjutas kogu järgnenud teatriperioodi, seda on kutsutud ka eesti teatri kuldajaks. SU M M A R Y Young directors emerged in Estonian theatre at the end of the 1960s. More specifically, during the years 1969–1974 many new directors’ names appeared on theatre posters, and the fundamental changes in the language and content of the theatre at the end of the 1960s and the 1970s began to be associated with these names. Most important among these are Evald Hermaküla, Jaan Tooming, Kalju Komissarov, and Karin Raid. Within a short time these young directors changed prevailing assumptions about the purpose, means, and content of the theatre in Estonia. This phenomenon came to be referred to as the breakthrough, or the new wave; later on, in sum, as the renewal of theatre. A generational change was taking place in the theatre, and in this framework a different language of theatre emerged, which began carrying innovative emotional and aesthetic paradigms. As in the Anglo-American cultural space, this new

  17. Comparação entre equações de referência e o teste de caminhada de seis minutos

    Directory of Open Access Journals (Sweden)

    Simone Korn

    2014-04-01

    Full Text Available INTRODUÇÃO: Devido à importância do teste de caminhada de seis minutos (TC6, algumas equações têm sido propostas para predizer o resultado esperado. OBJETIVO: Comparar os valores encontrados em diferentes equações de referência para predição da distância percorrida no TC6 em idosos praticantes de exercícios físicos. MÉTODOS: Participaram 696 idosos de ambos os sexos, sendo 600 mulheres e 96 homens, praticantes de exercícios físicos do Grupo de Estudos da Terceira Idade (GETI, Programa Viver Ativo e do Programa Saúde e Lazer. Para avaliar a resistência aeróbia, foi utilizado o TC6, conforme proposto por Rikli e Jones. Para o cálculo da distância percorrida prevista, foram utilizadas as equações de Enright & Sherrill, Troosters e Enright. Utilizou-se estatística descritiva e inferencial, com nível de significância de 5%. RESULTADOS: A média da distância percorrida prevista pelas equações foram 305,29±46,98 m, 529,05 ±50,31 m e 415,37±38,77 m, respectivamente. No TC6, a média foi de 513,05 ± 87,26 m. Observou-se correlação significativa (p < 0,001 entre o TC6 e as equações de Enright & Sherrill e Troosters. Na comparação entre os valores, nota-se que as equações de Enright & Sherrill e Enright subestimam e as de Troosters superestima a resistência aeróbia de idosos praticantes de exercícios físicos. CONCLUSÃO: As equações de referência para predição da distância percorrida no TC6 analisadas no presente estudo não refletem a resistência aeróbia de idosos praticantes de exercícios físicos. Novas equações e/ou variáveis devem ser incluídas para calcular com certa precisão a distância percorrida por idosos fisicamente ativos. Dessa forma, as equações analisadas no presente estudo devem ser utilizadas com cautela por pesquisadores e profissionais que lidam com este público no Brasil.

  18. Lower Leg Injury Reference Values and Risk Curves from Survival Analysis for Male and Female Dummies: Meta-analysis of Postmortem Human Subject Tests.

    Science.gov (United States)

    Yoganandan, Narayan; Arun, Mike W J; Pintar, Frank A; Banerjee, Anjishnu

    2015-01-01

    Derive lower leg injury risk functions using survival analysis and determine injury reference values (IRV) applicable to human mid-size male and small-size female anthropometries by conducting a meta-analysis of experimental data from different studies under axial impact loading to the foot-ankle-leg complex. Specimen-specific dynamic peak force, age, total body mass, and injury data were obtained from tests conducted by applying the external load to the dorsal surface of the foot of postmortem human subject (PMHS) foot-ankle-leg preparations. Calcaneus and/or tibia injuries, alone or in combination and with/without involvement of adjacent articular complexes, were included in the injury group. Injury and noninjury tests were included. Maximum axial loads recorded by a load cell attached to the proximal end of the preparation were used. Data were analyzed by treating force as the primary variable. Age was considered as the covariate. Data were censored based on the number of tests conducted on each specimen and whether it remained intact or sustained injury; that is, right, left, and interval censoring. The best fits from different distributions were based on the Akaike information criterion; mean and plus and minus 95% confidence intervals were obtained; and normalized confidence interval sizes (quality indices) were determined at 5, 10, 25, and 50% risk levels. The normalization was based on the mean curve. Using human-equivalent age as 45 years, data were normalized and risk curves were developed for the 50th and 5th percentile human size of the dummies. Out of the available 114 tests (76 fracture and 38 no injury) from 5 groups of experiments, survival analysis was carried out using 3 groups consisting of 62 tests (35 fracture and 27 no injury). Peak forces associated with 4 specific risk levels at 25, 45, and 65 years of age are given along with probability curves (mean and plus and minus 95% confidence intervals) for PMHS and normalized data applicable to

  19. Kerlinger's Criterial Referents Theory Revisited.

    Science.gov (United States)

    Zak, Itai; Birenbaum, Menucha

    1980-01-01

    Kerlinger's criterial referents theory of attitudes was tested cross-culturally by administering an education attitude referents summated-rating scale to 713 individuals in Israel. The response pattern to criterial and noncriterial referents was examined. Results indicated empirical cross-cultural validity of theory, but questioned measuring…

  20. Comparison of Occlusive and Open Application in a Psoriasis Plaque Test Design, Exemplarily Using Investigations of Mapracorat 0.1% Ointment versus Vehicle and Reference Drugs.

    Science.gov (United States)

    Wigger-Alberti, Walter; Williams, Ragna; von Mackensen, Yi-Ling; Hoffman-Wecker, Maciej; Grossmann, Ulrike; Staedtler, Gerald; Nkulikiyinka, Richard; Shakery, Kaweh

    2017-01-01

    Psoriasis plaque tests (PPTs) are important tools in the early phases of antipsoriatic drug development. Two distinct PPT design variants (open vs. occluded drug application) are commonly used, but no previous work has aimed to directly compare and contrast their performance. We compared the antipsoriatic efficacy of mapracorat 0.1% ointment and reference drugs reported in 2 separate studies, representing open and occluded PPT designs. The drug effect size was measured by sonography (mean change in echo-poor band thickness), chromametry, and standardized clinical assessment. Antipsoriatic effects were detectable for the study drugs in both occluded and open PPTs. Differences between the potency of antipsoriatic drugs and vehicle were observable. The total antipsoriatic effect size appeared to be higher in the occluded PPT than the open PPT, despite the shorter treatment duration (2 vs. 4 weeks). Effect dynamics over time revealed greater differences between some study drugs in the open PPT compared to the occluded PPT. Taking the higher technical challenges for the open PPT into account, we recommend the occluded PPT as a standard screening setting in early drug development. In special cases, considering certain drug aspects or study objectives that would require procedural adaptations, an open PPT could be the better-suited design. Finally, both PPT models show clear advantages: classification as phase I studies, small number of psoriatic subjects, relatively short study duration, excellent discrimination between compounds and concentrations, parallel measurement of treatment response, and go/no go decisions very early in clinical development. © 2017 S. Karger AG, Basel.

  1. Normative reference values for the 20-meter shuttlerun test in a population-based sample of schoolchildren in Bogota, Colombia: The FUPRECOL Study

    OpenAIRE

    Palacios-López, Adalberto

    2016-01-01

    Our aim was to determine the normative reference values of cardiorespiratory fitness (CRF) and to establish the proportion of subjects with low CRF suggestive of future cardio-metabolic risk. Our aim was to determine the normative reference values of cardiorespiratory fitness (CRF) and to establish the proportion of subjects with low CRF suggestive of future cardio-metabolic risk. Methods: A total of 7244 children and adolescents attending public schools in Bogota, Colomb...

  2. GDB Pocket Reference

    CERN Document Server

    Robbins, Arnold

    2009-01-01

    The GNU debugger is valuable for testing, fixing, and retesting software because it allows you to see exactly what's going on inside of a program as it's executing. This new pocket reference shows you how to specify a target for debugging, perform a careful examination to find the cause of program failure, and make quick changes for further testing. The guide covers several popular programming languages.

  3. Iseseisvusdeklaratsioonid 1776–1918. The Estonian Declaration of Sovereignty: An Example of the Civilizing Force of Hypocrisy

    Directory of Open Access Journals (Sweden)

    Hent Kalmo

    2012-06-01

    Full Text Available Sovereignty has been characterised as a form of “organized hypocrisy”, a system governed by a set of rules that are generally recognised as binding and yet are continually infringed upon by the most powerful actors. This idea can be extended to analyse the role of sovereignty within the Soviet Union. The Soviet Union was nominally governed by a Constitution which endowed the Union Republics with the right of secession, but there was no realistic possibility of exercising this right. One should not rush to conclude, however, that the actual wording of the Soviet Constitution of 1977 was entirely without relevance. As Jon Elster has argued, hypocrisy can have a “civilizing force” when the need to appear impartial and to retain public credibility forces actors to choose a strategy they would not choose otherwise. A good example of this kind of argumentative constraint is offered by the dilemma faced by the Soviet leadership after the mid-1980s, as it became reluctant to use military force to suppress independence movements within the Baltic States while, at the same time, promising to give more weight to the Soviet Constitution and respect the “sovereignty” of the Union Republics. In this setting, the ambiguity of the word “sovereignty” could be played upon by a whole gamut of political movements in order to further their agenda, from local communists eager to expand their autonomy within the Soviet system to those making an explicit bid for the restoration of independence. Significant legal and political changes could be justified as mere conclusions from the constitutionally recognised status of the Union Republics – a strategy which was all the more effective as Moscow struggled to formulate an alternative line of constitutional interpretation that could be used to counter the Baltic claims. This exchange of opinions escalated into a constitutional conflict in November 1988, when the Estonian Supreme Soviet responded to

  4. Individual and work-related risk factors for musculoskeletal pain: a cross-sectional study among Estonian computer users.

    Science.gov (United States)

    Oha, Kristel; Animägi, Liina; Pääsuke, Mati; Coggon, David; Merisalu, Eda

    2014-05-28

    Occupational use of computers has increased rapidly over recent decades, and has been linked with various musculoskeletal disorders, which are now the most commonly diagnosed occupational diseases in Estonia. The aim of this study was to assess the prevalence of musculoskeletal pain (MSP) by anatomical region during the past 12 months and to investigate its association with personal characteristics and work-related risk factors among Estonian office workers using computers. In a cross-sectional survey, the questionnaires were sent to the 415 computer users. Data were collected by self-administered questionnaire from 202 computer users at two universities in Estonia. The questionnaire asked about MSP at different anatomical sites, and potential individual and work related risk factors. Associations with risk factors were assessed by logistic regression. Most respondents (77%) reported MSP in at least one anatomical region during the past 12 months. Most prevalent was pain in the neck (51%), followed by low back pain (42%), wrist/hand pain (35%) and shoulder pain (30%). Older age, right-handedness, not currently smoking, emotional exhaustion, belief that musculoskeletal problems are commonly caused by work, and low job security were the statistically significant risk factors for MSP in different anatomical sites. A high prevalence of MSP in the neck, low back, wrist/arm and shoulder was observed among Estonian computer users. Psychosocial risk factors were broadly consistent with those reported from elsewhere. While computer users should be aware of ergonomic techniques that can make their work easier and more comfortable, presenting computer use as a serious health hazard may modify health beliefs in a way that is unhelpful.

  5. Tõlkepärl eesti ilukirjanduse algusaegadest – esimene eestikeelne robinsonaad / A Translation Gem from the Beginnings of Estonian Literature - the First Robinsonade

    Directory of Open Access Journals (Sweden)

    Ave Mattheus

    2015-06-01

    Full Text Available Teesid: Artiklis uuritakse Eesti Kirjandusmuuseumis asuvat mahukat, ligi 800 lk tõlkekäsikirja „Norem Robinson“, mida võib pidada esimeseks eesti kirjanduse täiemahuliseks robinsonaadiks. Selle valmistas Pärnu koolmeister Heinrich Gottlieb Lorenzsonn saksa pedagoogi ja koolikirjaniku Joachim Heinrich Campe menukast noorsooromaanist „Robinson der Jüngere“ (1779–1780. Tõlge valmis 1822.–1823. aastal, kuid jõudis trükki alles 1842. aastal tugevasti kärbitud ja mugandatud kujul. Toetudes deskriptiivse tõlkeuurimuse analüüsikategooriatele, vaadeldakse artiklis, millised tegurid tõlkeprotsessi suunasid ja milline oli kultuuriruum, kuhu tõlge omal ajal paigutus. SU M M A R Y This article discusses a voluminous manuscript translation of almost 800 pages entitled Norem Robinson (Engl. Robinson the Younger, from the collections of the Estonian Literary Museum. This manuscript can be considered as the first complete Robinsonade in Estonian literature. Its author is a schoolteacher from Pärnu, Heinrich Gottlieb Lorenzsonn (1803–1847, who translated it from the youth novel Robinson der Jüngere(1779–1780, Engl. Robinson the Younger, a bestseller by the educator, writer and a major representative of German Enlightenment, Heinrich Joachim Campe. Lorenzsonn’s translation was completed in 1822–1823, but not printed until 1842 in a strongly adapted version titled Norema Robinsoni ello ja juhtumised ühhe tühja sare peäl (Engl. The Life and Adventures of Robinson the Younger on a deserted island. The print version of the Robinsonade lacks a pedagogical frame story, where the father tells children about the adventures of Robinson and takes the opportunity to discuss and imitate with children all the actions taken by Robinson the Younger. Due to this and other extirpated parts, the possible target audience was enlarged – besides children and youth, the text was now addressed to adults as well. In accordance with the

  6. Enterprise Reference Library

    Science.gov (United States)

    Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

    2011-01-01

    Introduction: Johnson Space Center (JSC) offers two extensive libraries that contain journals, research literature and electronic resources. Searching capabilities are available to those individuals residing onsite or through a librarian s search. Many individuals have rich collections of references, but no mechanisms to share reference libraries across researchers, projects, or directorates exist. Likewise, information regarding which references are provided to which individuals is not available, resulting in duplicate requests, redundant labor costs and associated copying fees. In addition, this tends to limit collaboration between colleagues and promotes the establishment of individual, unshared silos of information The Integrated Medical Model (IMM) team has utilized a centralized reference management tool during the development, test, and operational phases of this project. The Enterprise Reference Library project expands the capabilities developed for IMM to address the above issues and enhance collaboration across JSC. Method: After significant market analysis for a multi-user reference management tool, no available commercial tool was found to meet this need, so a software program was built around a commercial tool, Reference Manager 12 by The Thomson Corporation. A use case approach guided the requirements development phase. The premise of the design is that individuals use their own reference management software and export to SharePoint when their library is incorporated into the Enterprise Reference Library. This results in a searchable user-specific library application. An accompanying share folder will warehouse the electronic full-text articles, which allows the global user community to access full -text articles. Discussion: An enterprise reference library solution can provide a multidisciplinary collection of full text articles. This approach improves efficiency in obtaining and storing reference material while greatly reducing labor, purchasing and

  7. Multi-test analysis and model-based estimation of the prevalence of Taenia saginata cysticercus infection in naturally infected dairy cows in the absence of a 'gold standard' reference test.

    Science.gov (United States)

    Eichenberger, R M; Lewis, F; Gabriël, S; Dorny, P; Torgerson, P R; Deplazes, P

    2013-09-01

    The diagnostic values of seven serological tests (ELISAs) and of the obligatory European Union-approved routine visual meat inspection for the detection of Taenia saginata cysticercosis were investigated. A total of 793 slaughtered dairy cows were selected in three European Union approved abattoirs in Switzerland, an endemic area (apparent prevalence by enhanced meat inspection up to 4.5%) with typically low parasite burdens. ELISAs based on a somatic larval antigen, isoelectric focused somatic larval antigen, larval excretory/secretory antigens, peptide HP6-2, peptide Ts45S-10, pooled peptide solution and a monoclonal antibody antigen capture assay were initially screened. As there is no perfect diagnostic 'gold standard' reference test, the obligatory meat inspection and four selected serological tests were further analysed using Bayesian inference to estimate the "true" prevalence and the diagnostic test sensitivities and specificities. The ELISA for specific antibody detection based on excretory/secretory antigens showed highest sensitivity and specificity with 81.6% (95% credible interval: 70-92) and 96.3% (95% credible interval: 94-99), respectively. The Bayesian model estimated the specificity of the ELISA, based on the synthetic peptide Ts45S-10 as 55.2% (95% credible interval: 46-65) and sensitivity as 84.7% (95% credible interval: 82-88). The sensitivity of the ELISA based on mAbs, detecting circulating antigen, was 14.3% (95% credible interval: 9-23) with a specificity of 93.7% (95% credible interval: 92-96). The diagnostic sensitivity of the obligatory standard European Union meat inspection procedure for the detection of T. saginata cysticercus infection at the abattoir was estimated to be 15.6% (95% credible interval: 10-23). Based on these data, the modelled prevalence of cysticercosis in dairy cows presented at abattoirs in Switzerland was estimated to be 16.5% (95% credible interval: 13-21). These cattle also had a high prevalence of infection with

  8. Valores de referência para o teste de caminhada com carga progressiva em indivíduos saudáveis: da distância percorrida às respostas fisiológicas Reference values for the incremental shuttle walk test in healthy subjects: from the walk distance to physiological responses

    Directory of Open Access Journals (Sweden)

    Victor Zuniga Dourado

    2013-04-01

    Full Text Available OBJETIVO: Determinar valores de referência para a distância caminhada (DC e para respostas fisiológicas durante o teste de caminhada com carga progressiva (TCCP e desenvolver equações preditivas para essas variáveis em adultos saudáveis. MÉTODOS: Foram avaliados 103 participantes saudáveis com idade > 40 anos (54 mulheres e 49 homens. Os participantes usaram um sistema de análise de gases durante o TCCP. Consumo de oxigênio (VO2, liberação de gás carbônico, ventilação minuto, FC, DC e velocidade máxima da caminhada (VMC foram obtidos como desfechos primários. Avaliamos também a força de preensão manual (FPM e a massa magra corporal (MMC. RESULTADOS: Os modelos de regressão utilizando variáveis fisiológicas, DC e VMC ajustados por idade, massa corporal, estatura e sexo apresentaram valores de R² entre 0,40 e 0,65 (para FC e pico de VO2, respectivamente. Os modelos incluindo MMC e FPM não aumentaram consideravelmente os valores de R² na previsão do pico de VO2, embora esses modelos tenham aumentado discretamente os valores do R² para DC e VMC (8% e 12%, respectivamente. As variáveis DC, VMC e DC × massa corporal, respectivamente, explicaram 76,7%, 73,3% e 81,2% da variabilidade do pico de VO2. CONCLUSÕES: Nossos resultados originaram valores de referência para a DC e respostas fisiológicas ao TCCP, que podem ser estimados adequadamente por características demográficas e antropométricas simples em adultos saudáveis com idade > 40 anos. O TCCP poderia ser utilizado na avaliação da capacidade física na população geral de adultos e no desenvolvimento de programas de caminhada individualizados.OBJECTIVE: To determine reference values for incremental shuttle walk distance (ISWD and peak physiological responses during the incremental shuttle walk test (ISWT, as well as to develop a series of predictive equations for those variables in healthy adults. METHODS: We evaluated 103 healthy participants > 40 years of

  9. On using an efficiency matrix in analysing profit per employee (on the basis of the Estonian SME software sector) 

    OpenAIRE

    Paavo Siimann; Jaan Alver

    2015-01-01

    Service companies earn their profit mainly due to their employees’ intellectual skills, therefore, increasing profit per employee is one opportunity to increase profit and thereby also the company’s market value. In this article the number of employees, the value of owners’ equity and loan capital, operating expenses, net sales and profit before income tax have been used to analyse the change in profit per employee of the Estonian software small and medium-sized enterprise (SME) sector in ...

  10. 'No, Facebook isn't distracting me, I can study at night': ICT habits and boundary management among Estonian secondary pupils

    OpenAIRE

    Marcus Persson

    2014-01-01

    The topic of this article is the use of information and communication technologies (computers, tablets, and mobile phones) in adolescents and boundary management between mental domains (school and home domain). More specifically, how do Estonian secondary pupils perceive and manage mental boundaries between school work and leisure activities in environments with ubiquitous access to ICT. Building on a mixed methods study consisting of a web survey with structured, closed-ended questions and o...

  11. Non-market value of Estonian seminatural grasslands: a contingent valuation study. Eesti poolloodusliku rohumaa turuväline väärtus: tingliku hindamise uuring

    Directory of Open Access Journals (Sweden)

    Helli Lepasaar

    2015-12-01

    Full Text Available Seminatural grasslands i.e. the floodplain meadows, seashore meadows, wooded meadows, dry meadows, wooded pastures are the very traditional part of Estonian landscapes, which play an important role in the appearance of the landscape in general and also serve as an important habitat for many plant and animal species. In order to preserve the seminatural grasslands continuous annual mowing and/or pasturing is needed. This activity is not economically profitable and needs subsidizing. The authors of the work raise a hypothesis that the Estonian seminatural grasslands could be viewed as a valuable non-market environmental good for which a significant public demand exists. In order to find out the non-market value of the seminatural grasslands a contingent valuation study was carried out among the Estonian working-age population (size of the sample 1061 individuals. The average individual willingness to pay was 11.3 euros. During the study, the authors constructed the total demand function and discovered that the total annual demand for seminatural grasslands was 17.9 million euros.

  12. Breast milk cytokine and IgA composition differ in Estonian and Swedish mothers-relationship to microbial pressure and infant allergy.

    Science.gov (United States)

    Tomicić, Sara; Johansson, Git; Voor, Tiia; Björkstén, Bengt; Böttcher, Malin Fagerås; Jenmalm, Maria C

    2010-10-01

    The immune system of the neonate is influenced by maternal immunity during pregnancy and lactation. An altered microbial exposure, possibly underlying the increase of allergic diseases in affluent societies, may affect maternal breast milk immune composition. Secretory IgA (SIgA), IL-4, IL-10, IL-13, IFN-[gamma], TGF-[beta]1, and TGF-[beta]2 were analyzed with ELISA in colostrum and 1-mo mature milk from mothers from Estonia (n = 39) and Sweden (n = 60), the two geographically adjacent countries with different living conditions and allergy incidence. The IL-10 and IFN-[gamma] levels were higher in colostrum from Estonian than Swedish mothers, whereas the opposite was true for TGF-[beta]2. In mature milk, higher SIgA and IFN-[gamma] levels but lower TGF-[beta]1 and TGF-[beta]2 levels were observed in Estonian than Swedish mothers. Interestingly, in Sweden but not Estonia, the TGF-[beta]1 and TGF-[beta]2 levels correlated inversely with environmental endotoxin concentrations, whereas positive correlations to microbial load were observed for IL-4, IL-10, and IFN-[gamma]. High colostral IL-13 levels were associated with allergic sensitization during infancy in Sweden. In conclusion, Estonian mothers have lower breast milk levels of TGF-[beta], particularly TGF-[beta]2, but higher levels of SIgA, IL-10, and IFN-[gamma] than Swedish mothers, possibly because of differences in microbial load.

  13. Superior performance of constant-saltier-reference DTF and DTFM to same-different tests by consumers for discriminating products varying sodium contents

    DEFF Research Database (Denmark)

    Choi, Yoon-Jung; Kim, Jin-Young; Christensen, Rune Haubo Bojesen

    2014-01-01

    Reducing sodium content in foods and beverages has become very important, and great efforts are being made to achieve this while maintaining overall taste/acceptance of food. This requires more robust sensory discrimination test methods in terms of operational power because discrimination tests u...... when using naïve consumer subjects and when the sample in the first position in a test was a stronger (saltier) sample. This observation granted operational superiority to the DTF and DTFM in comparison to the same-different test, using the stronger (saltier) product as a constant...

  14. Bernhard Linde. Noor-Eesti vooriülem. Bernhard Linde. Leader of the Young Estonian Pack

    Directory of Open Access Journals (Sweden)

    Jaanus Kulli

    2012-04-01

    Full Text Available Bernhard Linde (1886–1954 was a recognized and prolific Estonian theatre critic of the first quarter of the 20th century, who mediated and propagated western as well as eastern European theatrical innovations. In addition, he was active as a literary and art critic, publisher, and proponent of libraries, to a modest extent he was a prose writer and poet. Unquestionably, however, Bernhard Linde’s most prominent role was as one of the founding members of the literary movement Young Estonia. He was the group’s first general manager; later on, he was the secretary of the Estonian Writers’ Association Young Estonia, and the chairman of the board of the Young Estonia Publishing House. Linde’s formal education culminated in graduation from Tartu University as a Slavic philologist; he was the only member of the Young Estonia group to demonstrate serious and sustained interest toward Slavic cultures and peoples. Linde was a contradictory figure, evoking a range of responses from his contemporaries: on the one hand, there was the unbelievably broad range of his participation in cultural life, his organizing skills and business instincts in directing publishing houses; on the other hand, a superficiality in his writings, his often rash and subjective style as a critic, and his financial intrigues. If one adds in Linde’s stubbornness, egocentrism, and intense spirit of protest, which often led to lawsuits, the outcome is the portrait of an extremely complicated, fascinating, and passionate man—both in his creative work and his personal life Linde guaranteed a place for himself in literary history through a small catch of texts: a few foundational essays (for example, on August Kitzberg, a translation of Balzac’s Le père Goriot, the essay collection Omad ja võõrad (Own and Foreign and a travel book focusing on the literature and theatre of eastern Europe (Loova Kesk-Euroopa Poole (Toward A Creative Central Europe. The prominent public

  15. Application of the reference method isotope dilution gas chromatography mass spectrometry (ID/GC/MS) to establish metrological traceability for calibration and control of blood glucose test systems.

    Science.gov (United States)

    Andreis, Elisabeth; Küllmer, Kai; Appel, Matthias

    2014-05-01

    Self-monitoring of blood glucose (BG) by means of handheld BG systems is a cornerstone in diabetes therapy. The aim of this article is to describe a procedure with proven traceability for calibration and evaluation of BG systems to guarantee reliable BG measurements. Isotope dilution gas chromatography mass spectrometry (ID/GC/MS) is a method that fulfills all requirements to be used in a higher-order reference measurement procedure. However, this method is not applicable for routine measurements because of the time-consuming sample preparation. A hexokinase method with perchloric acid (PCA) sample pretreatment is used in a measurement procedure for such purposes. This method is directly linked to the ID/GC/MS method by calibration with a glucose solution that has an ID/GC/MS-determined target value. BG systems are calibrated with whole blood samples. The glucose levels in such samples are analyzed by this ID/GC/MS-linked hexokinase method to establish traceability to higher-order reference material. For method comparison, the glucose concentrations in 577 whole blood samples were measured using the PCA-hexokinase method and the ID/GC/MS method; this resulted in a mean deviation of 0.1%. The mean deviation between BG levels measured in >500 valid whole blood samples with BG systems and the ID/GC/MS was 1.1%. BG systems allow a reliable glucose measurement if a true reference measurement procedure, with a noninterrupted traceability chain using ID/GC/MS linked hexokinase method for calibration of BG systems, is implemented. Systems should be calibrated by means of a traceable and defined measurement procedure to avoid bias. © 2014 Diabetes Technology Society.

  16. Barriers to Pap Smear Test for the Second Time in Women Referring to Health Care Centers in the South of Tehran: A Qualitative Approach.

    Science.gov (United States)

    Hassani, Laleh; Dehdari, Tahereh; Hajizadeh, Ebrahim; Shojaeizadeh, Davoud; Abedini, Mehrandokht; Nedjat, Saharnaz

    2017-10-01

    Cervical cancer is a preventable disease with a regular screening program. Many studies have reported a large number of barriers that women had for the first time, but this study decided to find other barriers for the second time pap smear. In this qualitative research, data were gathered through in-depth interviews and expressed through conventional content analysis in the form of constant comparison. The participants were 15 women with family profile at 30 health care centers who lived in the south of Tehran and had done Pap smear for one time but didn't do it for the second time. Three main themes emerged from the analysis of the interviews: negative experiences of the first Pap test were as follows: results of the first time test, readiness for performing the test, getting the test itself, and the site of the first Pap test. Personal barriers to getting the second Pap test were: inattention to time, physical barriers to the second Pap test, and inhibitory beliefs. Perceived social barriers to getting the second Pap test with two sub-themes included social supports and abstract norms. This study provided other barriers about Pap smear including lack of the spouse's support, the role of health care providers and physicians in screening program for early diagnosis in women.

  17. Discrepant test findings in early infant diagnosis of HIV in a national reference laboratory in Kenya: challenges and opportunities for programs.

    Science.gov (United States)

    Kageha, Sheila; Okoth, Vincent; Kadima, Silvia; Vihenda, Stella; Okapesi, Elphas; Nyambura, Elizabeth; Maiyo, Alex; Ndung'u, Nancy; Khamadi, Samoel; Mwau, Matilu

    2012-08-01

    In Kenya, the availability of a cheap diagnostic service for HIV-exposed infants has helped scale-up access to treatment, and provided a means by which programs that support Prevention of Mother to Child Transmission of HIV can be evaluated. As expected for any large testing program, discrepant and indeterminate results present a significant challenge. Dried Blood Spots were collected from health centers countrywide and couriered to four laboratories for tests. Results were dispatched either by email, telephone, GSM SMS printer or courier. Between 2006 and 2009, tests were conducted with the Manual Roche v. 1.5 Assay. In 2010 the labs switched fully to the Cobas® AmpliPrep/ Cobas® TaqMan® HIV-1 Qual automated Roche Test. Between 2006 and 2010, the KEMRI CVR EID Lab conducted 64 591 HIV tests in on children HIV tests (38 834) used the manual assay, while 17 133 tests used the automated assay. Overall, 10.7% (6915) of the samples tested positive, while 86.6% (55 967) tested negative. A total of 1.6% (1041) tested indeterminate and required a re-bleed of the infant. Two hundred positive tests by the manual assay were retrieved randomly and retested using the automated assay. Among them, 192 (96%) remained positive, 5 (2.5%) were negative while 3 (1.5%) failed. A total of 160 negative samples by the manual assay were retrieved and retested with the automated assay. Among them, 154 (96.24%) remained negative, 3 (1.88%) tested positive while 3 (1.88%) failed. A total of 215 samples that gave indeterminate results by the manual assay were retested using the automated system. Among them, 62 (28.8%) gave positive results, 144 (66.97%) negative and 6 (2.8%) samples still gave discrepant results. Three (1.4%) did not amplify successfully. A few infants who were apparently positive appeared to test HIV negative with age. Indeterminate results are a significant challenge for HIV diagnostic services, as seen in the Kenyan EID Program. In our experience, they are more

  18. A Jeziorski-Monkhorst fully uncontracted multi-reference perturbative treatment. I. Principles, second-order versions, and tests on ground state potential energy curves

    Science.gov (United States)

    Giner, Emmanuel; Angeli, Celestino; Garniron, Yann; Scemama, Anthony; Malrieu, Jean-Paul

    2017-06-01

    The present paper introduces a new multi-reference perturbation approach developed at second order, based on a Jeziorski-Mokhorst expansion using individual Slater determinants as perturbers. Thanks to this choice of perturbers, an effective Hamiltonian may be built, allowing for the dressing of the Hamiltonian matrix within the reference space, assumed here to be a CAS-CI. Such a formulation accounts then for the coupling between the static and dynamic correlation effects. With our new definition of zeroth-order energies, these two approaches are strictly size-extensive provided that local orbitals are used, as numerically illustrated here and formally demonstrated in the Appendix. Also, the present formalism allows for the factorization of all double excitation operators, just as in internally contracted approaches, strongly reducing the computational cost of these two approaches with respect to other determinant-based perturbation theories. The accuracy of these methods has been investigated on ground-state potential curves up to full dissociation limits for a set of six molecules involving single, double, and triple bond breaking together with an excited state calculation. The spectroscopic constants obtained with the present methods are found to be in very good agreement with the full configuration interaction results. As the present formalism does not use any parameter or numerically unstable operation, the curves obtained with the two methods are smooth all along the dissociation path.

  19. The homogeneity testing of EtG in hair reference materials: a high-throughput procedure using GC-NCI-MS.

    Science.gov (United States)

    Mönch, Bettina; Becker, Roland; Jung, Christian; Nehls, Irene

    2013-03-10

    The validation of a robust quantification procedure for EtG in hair using GC-NCI-MS is presented. Aqueous extraction is followed by complete lyophylization of the extract and derivatization with pentafluoropropionic anhydride (PFPA) under controlled temperature and duration. Clean-up of extracts was dispensable and standard single quadrupole MS displayed sufficient selectivity and sensitivity. The method displayed a wide linearity range and enabled LOD of 0.68 pg/mg, LOQ of 2.4 pg/mg, and precision below 8.12%. Since EtG was seen to display prolonged stability in the aqueous extracts and after derivatization with PFPA this straightforward procedure allows a routine throughput of large quantities of samples with little proneness to procedural scatter of results. The method was applied to demonstrate the homogeneity of two hair reference materials with mean EtG contents of 8.48 pg/mg and 22.0 pg/mg. Aside from the application in homogeneity studies of hair reference materials predominantly in the concentration range of 10-50 pg/mg the method was also designed for daily routine quantification of real-world sample with regard to drinking behavior assessment. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  20. Experiences of a long-term randomized controlled prevention trial in a maiden environment: Estonian Postmenopausal Hormone Therapy trial

    Directory of Open Access Journals (Sweden)

    Rahu Mati

    2008-08-01

    Full Text Available Abstract Background Preventive drugs require long-term trials to show their effectiveness or harms and often a lot of changes occur during post-marketing studies. The purpose of this article is to describe the research process in a long-term randomized controlled trial and discuss the impact and consequences of changes in the research environment. Methods The Estonian Postmenopausal Hormone Therapy trial (EPHT, originally planned to continue for five years, was planned in co-operation with the Women's International Study of Long-Duration Oestrogen after Menopause (WISDOM in the UK. In addition to health outcomes, EPHT was specifically designed to study the impact of postmenopausal hormone therapy (HT on health services utilization. Results After EPHT recruited in 1999–2001 the Women's Health Initiative (WHI in the USA decided to stop the estrogen-progestin trial after a mean of 5.2 years in July 2002 because of increased risk of breast cancer and later in 2004 the estrogen-only trial because HT increased the risk of stroke, decreased the risk of hip fracture, and did not affect coronary heart disease incidence. WISDOM was halted in autumn 2002. These decisions had a major influence on EPHT. Conclusion Changes in Estonian society challenged EPHT to find a balance between the needs of achieving responses to the trial aims with a limited budget and simultaneously maintaining the safety of trial participants. Flexibility was the main key for success. Rapid changes are not limited only to transiting societies but are true also in developed countries and the risk must be included in planning all long-term trials. The role of ethical and data monitoring committees in situations with emerging new data from other studies needs specification. Longer funding for preventive trials and more flexibility in budgeting are mandatory. Who should prove the effectiveness of an (old drug for a new preventive indication? In preventive drug trials companies may