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Sample records for essay anomalias congenitas

  1. Congenital anomalies of the inferior vena cava: importance of multiplanar imaging methods: an iconographic essay; Anomalias congenitas da veia cava inferior: valor dos metodos multiplanares em seu diagnostico - ensaio iconografico

    Energy Technology Data Exchange (ETDEWEB)

    Viana, Sergio Lopes; Mendonca, Jose Luiz Furtado de; Freitas, Flavia Mendes Oliveira [Clinica Radiologica Vila Rica, Brasilia, DF (Brazil)] (and others). E-mail: radiolog@uol.com.br

    2006-10-15

    The inferior vena cava is the result of a complex embryologic process which takes place between 6 and 8 weeks of intra-uterine life. Several variations can occur during this process, and a defective embryogenesis of this vessel may lead to the development of anatomic variants. Although many of these variants are asymptomatic, the radiologist should be aware of them and of the potential medico-legal issues involved, especially in cases in which abdominal surgery or hemodynamic procedures are contemplated. In this paper, the major congenital anomalies involving the inferior vena cava are reviewed under the form of a pictorial essay, highlighting the role of the multiplanar imaging methods (volumetric computed tomography and magnetic resonance imaging) in their diagnosis. Keywords: Congenital variations; Inferior vena cava; Renal veins; Computed tomography; Magnetic resonance imaging. author)

  2. Pachyonychia Congenita

    Science.gov (United States)

    ... Bullosa Lichen Sclerosus Pachyonychia Congenita Pemphigus Psoriasis Raynaud’s Phenomenon Rosacea Vitiligo All Diseases and Conditions Kids Pages ... on the soles of the feet when a child begins to walk. In some cases, blisters and ...

  3. Spondyloepiphyseal dysplasia congenita

    International Nuclear Information System (INIS)

    Macpherson, R.I.; Wood, B.P.

    1980-01-01

    Spondyloepiphyseal dysplasia congenita is a form of primarily short trunk dwarfism, that is manifest at birth but generally has not been regarded as a cause of lethal neonatal dwarfism. Seven neonates with severe dwarfism are presented. The first survived the newborn period, but the other six were early neonatal deaths. All displayed the clinical and radiologic features of spondyloepiphyseal dysplasia congenita. The striking similarities between spondyloepiphyseal dysplasia congenita and achondrogenesis type 2 are discussed. (orig.) [de

  4. Anomalia Pierre Robin: cuidados

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    Maria Irene Bachega

    1985-12-01

    Full Text Available A anomalia de Pierre Robin, ocupa papel relevante nas ações de saúde do Hospital de Pesquisa e Reabilitação de Lesões Lábio-Palatais (HPRLLP, pelas suas características peculiares (micrognatia, glossoptose, palato hiperarqueado ou fissurado, língua ocupando posição retraída, ocasionando cianose, tiragem, opistotomo e pneumonias de aspiração, exigindo, portanto, cuidados médicos e de enfermagem específicos. Dentre as malformações associadas a fissura lábio-palatal, a anomalia de Pierre Robin é a que apresenta maior freqüência, exigindo maiores cuidados, daí a importância de podermos relatar a Pesquisa realizada em nosso serviço, fornecendo aos profissionais de saúde, subsídios para que possam delinear uma abordagem eficaz, orientando os cuidados referentes ao posicionamento da criança, técnica de alimentação, e assistência pré e pós-operatória.

  5. Anomalia anorretal e cuidados maternos

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    Manuela Costa Melo

    Full Text Available O objetivo deste artigo foi realizar um estudo de revisão bibliográfica sobre anomalia anorretal e cuidados maternos. O assunto foi abordado por meio de revisão integrativa realizada em consulta de artigos publicados nas bases de dados indexados na Biblioteca Virtual em Saúde. Foram identificadas 25 publicações que atenderam aos critérios de inclusão e exclusão pré-estabelecidos. Nos estudos analisados observaram-se distintos desenhos metodológicos demonstrando que algumas crianças nascidas com anomalia anorretal necessitam de cirurgia de urgência. Os profissionais de saúde, juntamente aos pais, precisam desenvolver parcerias que possibilitem um acompanhamento a longo prazo e orientações cuidadosas. Faz-se necessário que novas pesquisas sejam realizadas sobre o tema, com propostas metodológicas que retratem melhor a essência do cuidado com as crianças estomizadas

  6. Anomalia anorretal e cuidados maternos

    Directory of Open Access Journals (Sweden)

    Manuela Costa Melo

    2011-02-01

    Full Text Available O objetivo deste artigo foi realizar um estudo de revisão bibliográfica sobre anomalia anorretal e cuidados maternos. O assunto foi abordado por meio de revisão integrativa realizada em consulta de artigos publicados nas bases de dados indexados na Biblioteca Virtual em Saúde. Foram identificadas 25 publicações que atenderam aos critérios de inclusão e exclusão pré-estabelecidos. Nos estudos analisados observaram-se distintos desenhos metodológicos demonstrando que algumas crianças nascidas com anomalia anorretal necessitam de cirurgia de urgência. Os profissionais de saúde, juntamente aos pais, precisam desenvolver parcerias que possibilitem um acompanhamento a longo prazo e orientações cuidadosas. Faz-se necessário que novas pesquisas sejam realizadas sobre o tema, com propostas metodológicas que retratem melhor a essência do cuidado com as crianças estomizadas

  7. Characterization of a group unrelated patients with arthrogryposis multiplex congenita

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    Margarita Valdés-Flores

    2016-01-01

    analisados os fatores ambientais, pré-natais e o histórico familiar. Relatamos as anomalias cromossômicas e as entidades clínicas associadas com a Artrogripose múltipla congênita. Não havia nenhuma aberração cromossômica nos casos com retardo mental. Também encontramos 3 casos familiares não relacionados com Artrogripose múltipla congênita, em que são possíveis padrões de herança autossômica recessiva, autossômica dominante e ligada ao cromossomo X. Também analisamos a preocupação da literatura com a Artrogripose múltipla congênita. Conclusões: Reiteramos a ideia de que é importante estabelecer programas de fisioterapia e reabilitação específicos para os pacientes. É necessária uma abordagem multidisciplinar com cuidado médico, cirúrgico, de reabilitação, social e psicológico, incluindo aconselhamento genético. Keywords: Contracture, Arthrogryposis, Amyoplasia congenita, Palavras-chave: Contratura, Artrogripose, Amioplasia congênita

  8. Genetics Home Reference: dyskeratosis congenita

    Science.gov (United States)

    ... A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons. When dyskeratosis congenita is caused by mutations in other genes, it can be inherited in an autosomal dominant or autosomal recessive pattern. Autosomal dominant means one ...

  9. Aerobic training in myotonia congenita

    DEFF Research Database (Denmark)

    Andersen, Grete; Løkken, Nicoline; Vissing, John

    2017-01-01

    Introduction: Exercise has not been investigated in myotonia congenita (MC). We investigated whether regular aerobic training can reduce myotonia and improve fitness. Methods: Untrained patients with MC (age: 24–62 years; n = 6) completed 28 ± 3 sessions of 30-minute cycle ergometer training at 75......–17%; P = 0.02) and maximal workload by 10% (95% CI, 3–18%; P = 0.03). None of the myotonia tests changed in a clinically meaningful way. Conclusions: Regular endurance training improves fitness and maximal workload performance in patients with MC. The lack of creatine kinase elevations indicates...

  10. Incidental finding of cutaneous meningeal heterotopia in aplasia cutis congenita.

    Science.gov (United States)

    Kenyon, Katharine; Zedek, Daniel; Sayed, Christopher

    2016-07-01

    Aplasia cutis congenita and cutaneous meningeal heterotopia are both rare congenital conditions that most commonly occur on the scalp and may appear clinically and histologically similar. A subtype of aplasia cutis congenita, membranous aplasia cutis congenita, and cutaneous meningeal heterotopia are both proposed to result from neural tube closure errors. However, neither non-membranous nor membranous aplasia cutis congenita are known to occur together with cutaneous meningeal heterotopia in the same lesion. We report the incidental finding of cutaneous meningeal heterotopia within a lesion of aplasia cutis congenita. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  11. Pachyonychia congenita: A rare genodermatosis

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    Puneet Agarwal

    2013-01-01

    Full Text Available Pachyonychia congenita (PC is a rare genodermatosis with only 450 cases reported since 1906. It is of two types, type I due to mutation in genes 6a and 16, and 6b and 17 in type II with an autosomal dominant inheritance in both types. A 22 yr old female patient presented in our OPD with hypertrophy of finger and toe nails, palmoplantar keratoderma, oral punctuate leukokeratosis, hyperhidrosis in palms and soles with maceration and malodour since childhood. She had a positive family history with father and grandfather affected but less severely. Microscopy and culture of nail clippings and scrapping were done to rule out fungal infection. On biopsy acanthotic epidermis, parakeratosis, orthokeratosis were seen. No evidence of any associated malignancy was found after thorough workup. She was diagnosed as PC Type 1. She was put on topical steroids and orally on acetretin 25 mg OD. Paring of the nails was done too reduce the thickness of nails & to provide symptomatic relief. She was on a regular treatment for 3-4 months and showed some improvement in the form of reduced palmoplantar hyperkeratosis and reduced oral punctate keratosis but was later lost on followup. She showed no adverse effect to therapy during this period. This case is being reported because of its rarity.

  12. Valuing Essays: Essaying Values

    Science.gov (United States)

    Badley, Graham

    2010-01-01

    The essay regularly comes under attack. It is criticised for being rigidly linear rather than flexible and reflective. I first challenge this view by examining reasons why the essay should be valued as an important genre. Secondly, I propose that in using the essay form students and academics necessarily exemplify their own critical values. Essays…

  13. Clouston syndrome can mimic pachyonychia congenita

    NARCIS (Netherlands)

    van Steensel, MAM; Jonkman, MF; van Geel, M; Steijlen, PM; McLean, WHI; Smith, FJD

    2003-01-01

    We studied three families suffering from nail abnormalities who had previously been diagnosed as pachyonychia congenita. No keratin gene mutations were detected. Sequencing of connexin 30 (GJB6 gene) in these patients identified heterozygous missense mutations G11R and A88V that are known to be

  14. Spondyloepiphyseal dysplasia congenita. A cause of lethal neonatal dwarfism

    Energy Technology Data Exchange (ETDEWEB)

    Macpherson, R.I.; Wood, B.P.

    1980-07-01

    Spondyloepiphyseal dysplasia congenita is a form of primarily short trunk dwarfism, that is manifest at birth but generally has not been regarded as a cause of lethal neonatal dwarfism. Seven neonates with severe dwarfism are presented. The first survived the newborn period, but the other six were early neonatal deaths. All displayed the clinical and radiologic features of spondyloepiphyseal dysplasia congenita. The striking similarities between spondyloepiphyseal dysplasia congenita and achondrogenesis type 2 are discussed.

  15. Anomalias branquiais: revisão de 23 casos

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    Rogério Aparecido Dedivitis

    Full Text Available A anomalia branquial é a doença congênita mais comum vista pelo cirurgião de cabeça e pescoço. Vinte e três pacientes portadores de anomalias branquiais tratados no período de 1994 a 1997 foram revisados. O diagnóstico clínico foi documentado por ultra-sonografia e comprovado pelo exame histopatológico. Encontramos seis anomalias de primeiro arco (26%; 16 do segundo arco (69,5%; e uma do terceiro (4,5%. Não houve anomalia do quarto arco. Após um seguimento que variou de três a 43 meses, não houve caso de recidiva. A prevalência de anomalias do segundo arco é compatível com a literatura, porém, foi alta a incidência do primeiro arco. O emprego da técnica cirúrgica adequada, com a ressecção de todo o trajeto fistuloso, mostrou-se eficaz.

  16. CT of the congenital and spleen acquired abnormalities; TC de las anomalias congenitas y adquiridas del bazo

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    Gil, A.; Ibarburen, C.; Anton, E.; Temprano, C.; Salgado, F. M.; Davila, J. [Hospital de Mostoles. Madrid (Spain)

    2000-07-01

    This study aims to review the X-ray characteristics of the different entities that can affect the spleen by illustrating the semiology that is seen in the Computed tomography (CT). We review 239 cases of splenic pathology that occurred during a period of 15 years (1985-1999). All of the patients underwent a CT with and without i. v. contrast. Most of the patients were submitted to a splenectomy and histological correlation was performed. The CT is the imaging technique of choice in the diagnosis of splenic diseases since the ultrasonography, although a very sensitive technique, is very inspecific. (Author) 36 refs.

  17. Dyskeratosis Congenita: A Report of Two Cases

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    Anila Karunakaran

    2013-01-01

    Full Text Available Oral manifestations play an important role in the diagnosis of many systemic conditions. Dyskeratosis congenita (DC is a rare genodermatosis which exhibits oral leukoplakia, nail dystrophy, and reticular skin pigmentations as its primary features. DC has increased risk of developing constitutional anemias and malignancies and early diagnosis enables the patient to be monitored and proper interventional therapy to be instituted. Hence, dentists need to be aware of the various manifestations of this fatal syndrome. Only few cases have been reported on DC in the dental literature. Two cases of DC are reported here with a brief review of the literature.

  18. Prenatal diagnosis of hypophosphatasia congenita using ultrasonography

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    Guguloth, Ashwitha [Dept. of Radiology, Bangalore Medical College and Research Institute, Bangalore (India); Aswani, Yashant; Anandpara, Karan Manoj [Dept. of Radiology, Seth G S Medical College and KEM Hospital, Mumbai (India)

    2016-01-15

    Congenital hypophosphatasia is a rare fatal skeletal dysplasia. Antenatal determinants of Epub ahead of print lethality include small thoracic circumference with pulmonary hypoplasia and severe micromelia. These features were present in the fetus of a 25-year-old female who came for an anomaly scan in her second trimester of pregnancy. Additional findings of generalized demineralization and osteochondral spurs led to the diagnosis of hypophosphatasia congenita. The pregnancy was terminated, and the findings were confirmed on autopsy. Common differential diagnoses with clues to diagnose the above mentioned condition have been discussed here. Early and accurate detection of this medical condition is important as no treatment has been established for this condition. Therefore, antenatal ultrasonography helps in diagnosing and decision making with respect to the current pregnancy and lays the foundation for the genetic counseling of the couple.

  19. [Aplasia cutis congenita associated with epidermolysis bullosa].

    Science.gov (United States)

    Muñoz-Guerrero, Félix; Muñoz-Solís, Adrián Antonio; Ornelas-Aguirre, José Manuel

    2017-12-01

    Aplasia cutis congenita (ACC) is a skin condition of rare presentation, this disease is characterized by absence of skin at birth and associated with facial, skin and bone skull deformities. The diagnosis is mainly clinical. Male 5 days after birth, unique product of primigravida mother and no family history of relevance. Physical examination revealed bilateral and symmetrical skin defects of both lower extremities, the disease is characterized by skin fragility, scabs, and coated pseudomembrane ulcers, decreased interdigital space between toes of the left foot, retraction of the foot and genu varum. It was handled with allograft of epidermis cultured in vitro, general wound care and clinical follow-up. ACC associated with epidermolysis bullosa is one of the rarer forms of presentation. It is necessary to rule out other skin diseases. Clinical management is recommended with biological or synthetic skin cover, infection prevention, early treatment of complications and clinical follow. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

  20. Asymptomatic myotonia congenita unmasked by severe hypothyroidism.

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    Passeri, Elena; Sansone, Valeria A; Verdelli, Chiara; Mendola, Marco; Corbetta, Sabrina

    2014-04-01

    Myotonia congenita is an inherited muscle disorder sustained by mutations in the skeletal muscle chloride channel gene CLCN1. Symptoms vary from mild to severe and generalized myotonia and worsen with cold, stressful events and hormonal fluctuations. Here we report the case of a young woman who sought medical attention because of subacute onset of diffuse and severe limb myotonia. CLCN1 gene sequencing showed a heterozygous transversion (T550M), two polymorphisms and one silent mutation. Thyroid function screening revealed severe hypothyroidism. She was placed on l-thyroxine replacement therapy which dramatically improved myotonia. We conclude that hypothyroidism unmasked a genetically determined, clinically asymptomatic chloride channelopathy. Diagnostic work-up in patients with clinically isolated myotonia should not be limited to genetic screening of non-dystrophic or dystrophic myotonias. Considering the high prevalence of hypothyroidism in females, systematic thyroid function screening by looking for additional hypothyroid symptoms and serum TSH levels measurement is mandatory in these patients. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Dyskeratosis congenita in a Nigerian boy | Ibrahim | Nigerian ...

    African Journals Online (AJOL)

    Dyskeratosis congenita is a rare hereditary disease. It mainly affects males and manifest between 5 years and 12 years. Its classic manifestation consists of skin pigmentary changes, nail dystrophy, oral leukoplakia, bone marrow failure and predisposition to malignany. We report the case of a 9-year-old boy who presented ...

  2. Video essay

    DEFF Research Database (Denmark)

    2015-01-01

    Camera movement has a profound influence on the way films look and the way films are experienced by spectators. In this visual essay Jakob Isak Nielsen proposes six major functions of camera movement in narrative cinema. Individual camera movements may serve more of these functions at the same time...

  3. Ecosociological essays

    International Nuclear Information System (INIS)

    Vaillancourt, J.

    1982-01-01

    This book contains a collection of 25 essays, articles and reports of work in the domain of environmental sociology, a new area of sociology which can be labelled ΣecosociologyΣ. This area is situated on the border between sociology and ecology but from the point of view of sociology rather than that of ecology

  4. Localised form of spondylo-epiphyseal dysplasia congenita

    International Nuclear Information System (INIS)

    Hoeffel, J.C.; Mohy, R.; Collignon, P.; Moog, G.

    1988-01-01

    We report an unusual case of spondylo-epiphyseal dysplasia congenita which affected only the hips and the thoraco-lumbar spine. The epiphysis of the long bones are normal apart from the hips. Our child has a bilateral epiphyseal dysplasia of both proximal femoral epiphysis discovered incidentally at 11 months and confirmed later on at 8 years, associated with abnormalities of the superior margin of the vertebral bodies from T11 to L2. Very few similar cases have been reported anteriorly. (orig.) [de

  5. Dyskeratosis Congenita Associated Non-Specific Interstitial Pneumonia

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    Unnati D. Desai

    2017-01-01

    Full Text Available Dyskeratosis Congenita (DC is a rare inherited disorder of ectodermal dysplasia. It consists of a classical mucocutaneous triad of abnormal skin pigmentation, nail dystrophy and leukoplakia. Pulmonary disease is seen in 10-15%. It is characterized by Idiopathic Pulmonary Fibrosis (IPF, or Idiopathic Familial Pulmonary Fibrosis (IFPF. Non-specific Interstitial Pneumonia (NSIP has been reported rarely in children with DC and in an isolated adult patient. Our patient had classical clinical presentation of DC with pancytopenia and portal hypertension and clinic-radiological features of NSIP which is a rare association.

  6. RETINAL NEOVASCULARIZATION FROM A PATIENT WITH CUTIS MARMORATA TELANGIECTATICA CONGENITA.

    Science.gov (United States)

    Sassalos, Thérèse M; Fields, Taylor S; Levine, Robert; Gao, Hua

    2018-03-14

    To report a rare case of peripheral retinal neovascularization in a patient diagnosed with cutis marmorata telangiectatica congenita (CMTC). Observational case report. A 16-year-old girl was referred to clinic for retinal evaluation. The patient had a clinical diagnosis of CMTC later confirmed by skin biopsy. Examination revealed temporal peripheral retinal sheathing, as well as lattice degeneration in both eyes. Wide-field fluorescein angiogram showed substantive peripheral retinal nonperfusion with evidence of vascular leakage from areas of presumed retinal neovascularization. The patient subsequently had pan retinal photocoagulation laser treatment to each eye without complication. Cutis marmorata telangiectatica congenita is a rare vascular condition known to affect multiple organ systems including the eyes. Although ocular manifestations of CMTC are rare, instances of congenital glaucoma, suprachoroidal hemorrhage, and bilateral total retinal detachments resulting in secondary neovascular glaucoma have been reported. Our patient demonstrates the first reported findings of peripheral nonperfusion and retinal neovascularization related to CMTC in a 16-year-old girl. We propose early retinal examination, wide-field fluorescein angiogram, and early pan retinal photocoagulation laser treatment in patients with peripheral nonperfusion and retinal neovascularization from CMTC.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  7. Sexual Essays

    DEFF Research Database (Denmark)

    Giles, James

    Through a series of interrelated essays, this book explores fundamental issues concerning gender, sexual and romantic attraction, sexual desire and fantasies, the sexual positions, age dysphoria, and the role of naked skin in human sexuality. It does so by exploring experiential, social, biological...... on sex. It is further argued that sexual desire is an existential need based on the experience of having a gendered body. A case study of age dysphoria is presented showing how the conclusions concerning concerning gender and desire apply in an atypical case. The body's fundamental role in sexuality......, and evolutionary aspects of sexual life. The author criticizes several popular views, rejecting both social constructionist accounts of gender and social constructionist and biological accounts of sexual desire. It is argued instead that gender roles and gender are often confused and that gender itself is based...

  8. Chloride channels in myotonia congenita assessed by velocity recovery cycles.

    Science.gov (United States)

    Tan, S Veronica; Z'Graggen, Werner J; Boërio, Delphine; Rayan, Dipa Raja; Norwood, Fiona; Ruddy, Deborah; Howard, R; Hanna, Michael G; Bostock, Hugh

    2014-06-01

    Myotonia congenita (MC) is caused by congenital defects in the muscle chloride channel CLC-1. This study used muscle velocity recovery cycles (MVRCs) to investigate how membrane function is affected. MVRCs and responses to repetitive stimulation were compared between 18 patients with genetically confirmed MC (13 recessive, 7 dominant) and 30 age-matched, normal controls. MC patients exhibited increased early supernormality, but this was prevented by treatment with sodium channel blockers. After multiple conditioning stimuli, late supernormality was enhanced in all MC patients, indicating delayed repolarization. These abnormalities were similar between the MC subtypes, but recessive patients showed a greater drop in amplitude during repetitive stimulation. MVRCs indicate that chloride conductance only becomes important when muscle fibers are depolarized. The differential responses to repetitive stimulation suggest that, in dominant MC, the affected chloride channels are activated by strong depolarization, consistent with a positive shift of the CLC-1 activation curve. Copyright © 2013 Wiley Periodicals, Inc.

  9. An Uncommon Reason of Osteoporosis: Spondyloepiphyseal Dysplasia Congenita

    Directory of Open Access Journals (Sweden)

    Onur Elbasan

    2017-12-01

    Full Text Available Skeletal dysplasia is a complex and rare disease group that presents with clinical and radiological findings that differ from classical metabolic bone diseases in which bone and cartilage tissue are affected together. Spondyloepiphyseal dysplasia conjenita with involvement of the spine and long bone epiphyses is seen with short stature and short body from birth. Although bone deformities such as shortness of neck and vertebrae, kyphosis, scoliosis, pectus carinatum, genu varum or valgum are frequent, association with osteopenia/osteoporosis has been rarely reported. Although spondyloepiphyseal dysplasia tarda and osteopenia are coexisting in the literature, there is no evidence of the association of spondyloepiphyseal dysplasia tarda and conjunctiva with osteoporosis. In our case report, we presented a patient who was applied to our center with short stature, diagnosed with osteoporosis and spondyloepiphyseal dysplasia congenita by detecting femur head aplasia in radiological imaging.

  10. ANOMALIAS E RETORNO ACIONÁRIO: EVIDÊNCIAS EMPÍRICAS DO MERCADO BRASILEIRO

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    Márcio André Veras Machado

    2014-10-01

    Full Text Available Este artigo teve por objetivo analisar se anomalias de valor associadas a padrões comumente documentados no comportamento dos preços das ações existem no mercado acionário Brasileiro. Especificamente, este trabalho examina os retornos anormais produzidos por estratégias baseadas nos efeitos tamanho da empresa, book-to-market (B/M, estratégia momento, lucro/preço, fluxo de caixa/preço, liquidez e alavancagem, denominadas de anomalias de valor. Além de analisar tais anomalias, este artigo avalia a capacidade do CAPM e do modelo de três fatores de Fama e French (1993 em explicá-las. Para isso, em junho de cada ano, iniciando em 1995 e terminando em 2008, todas as ações foram ordenadas de forma decrescente e divididas em cinco carteiras, conforme a variável de interesse. Os resultados apresentados indicam evidências da existência do efeito liquidez, momento e índice BM, porém, nesse caso, contrário ao previsto na teoria. Por outro lado, não há evidências que suportem a existência dos efeitos lucro/preço, fluxo de caixa/preço, tamanho e alavancagem.

  11. Pachyonychia congenita: Report of two cases and mutation analysis

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    Jia-Ming Yeh

    2012-09-01

    Full Text Available Pachyonychia congenita (PC comprises a group of rare autosomal dominant genetic disorders that involve ectodermal dysplasia. It is characterized by hypertrophic nail dystrophy, focal palmoplantar keratoderma, follicular keratoses, and oral leukokeratosis. Historically, PC has been subdivided into two subtypes, PC-1 or PC-2, on the basis of clinical presentation. However, differential diagnosis based on clinical grounds, especially in young and/or not fully penetrant patients, can be difficult. In addition, clinical analysis of the large case series has shown that there is considerable phenotypic overlap between these two subtypes recently. Based on the advent of molecular genetics and the identification of the genes causing PC, more specific nomenclature has been adopted. Therefore, diagnosis at the molecular level is useful and important to confirm the clinical impression. In this report, we describe two typical cases of PC with mutation analysis revealed a small deletion (514_516delACC, Asn172del and a point mutation (487 G > A, GAG → AAG, Glu163Lys in the KRT6A gene.

  12. Constitutional mutations in RTEL1 cause severe dyskeratosis congenita.

    Science.gov (United States)

    Walne, Amanda J; Vulliamy, Tom; Kirwan, Michael; Plagnol, Vincent; Dokal, Inderjeet

    2013-03-07

    Dyskeratosis congenita (DC) and its phenotypically severe variant, Hoyeraal-Hreidarsson syndrome (HHS), are multisystem bone-marrow-failure syndromes in which the principal pathology is defective telomere maintenance. The genetic basis of many cases of DC and HHS remains unknown. Using whole-exome sequencing, we identified biallelic mutations in RTEL1, encoding a helicase essential for telomere maintenance and regulation of homologous recombination, in an individual with familial HHS. Additional screening of RTEL1 identified biallelic mutations in 6/23 index cases with HHS but none in 102 DC or DC-like cases. All 11 mutations in ten HHS individuals from seven families segregated in an autosomal-recessive manner, and telomere lengths were significantly shorter in cases than in controls (p = 0.0003). This group had significantly higher levels of telomeric circles, produced as a consequence of incorrect processing of telomere ends, than did controls (p = 0.0148). These biallelic RTEL1 mutations are responsible for a major subgroup (∼29%) of HHS. Our studies show that cells harboring these mutations have significant defects in telomere maintenance, but not in homologous recombination, and that incorrect resolution of T-loops is a mechanism for telomere shortening and disease causation in humans. They also demonstrate the severe multisystem consequences of its dysfunction. Copyright © 2013 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  13. Essays on Strategic Communication

    NARCIS (Netherlands)

    Z. Sharif (Zara)

    2016-01-01

    markdownabstractThree essays on strategic communication are discussed in this dissertation. These essays consider different settings in which a decision maker has to rely on another agent for information. In each essay, we analyze how much information the sender is able to credibly communicate to

  14. Multitemporalidade das anomalias da temperatura de superfície: o caso da cidade de Iporá, Brasil

    Directory of Open Access Journals (Sweden)

    Elis Alves

    2017-12-01

    Full Text Available O objetivo desta pesquisa foi analisar, a partir de dados do satélite Landsat - 5, o padrão multitemporal e espacial das anomalias térmicas na cidade de Iporá - Goiás. Para tanto, foram utilizadas imagens multiespectrais (banda termal do satélite Landsat 5, dos anos de 1984 a 2011. Para o processamento das imagens foram desenvolvidos modelos matemáticos por meio da ferramenta Model Maker do software Erdas Imagine 11. Os resultados evidenciaram que: 1 - com a utilização das anomalias térmicas, os mapas ficaram homogêneos, o que possibilitou comparação temporal; 2 - Anomalias térmicas máximas de superfície ocorreram em áreas de pouca urbanização, com solo exposto; 3 - O maior número de anomalias positivas ocorreu nas áreas de baixa urbanização, com solos expostos. Enquanto que nas áreas mais urbanizadas com presença de vegetação e próximas a superfície de água, ocorreu a maior quantidade de anomalias negativas; 4 - Nos pontos B, E, F e H foram observadas tendências estatisticamente significativas.

  15. Clinical and genetic features of dyskeratosis congenita, cryptic dyskeratosis congenita, and Hoyeraal-Hreidarsson syndrome in Japan.

    Science.gov (United States)

    Yamaguchi, Hiroki; Sakaguchi, Hirotoshi; Yoshida, Kenichi; Yabe, Miharu; Yabe, Hiromasa; Okuno, Yusuke; Muramatsu, Hideki; Takahashi, Yoshiyuki; Yui, Shunsuke; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Miyano, Satoru; Inokuchi, Koiti; Ito, Etsuro; Ogawa, Seishi; Kojima, Seiji

    2015-11-01

    Dyskeratosis congenita (DKC) is an inherited bone marrow failure (BMF) syndrome typified by reticulated skin pigmentation, nail dystrophy, and mucosal leukoplakia. Hoyeraal-Hreidarsson syndrome (HHS) is considered to be a severe form of DKC. Unconventional forms of DKC, which develop slowly in adulthood but without the physical anomalies characteristic of DKC (cryptic DKC), have been reported. Clinical and genetic features of DKC have been investigated in Caucasian, Black, and Hispanic populations, but not in Asian populations. The present study aimed to determine the clinical and genetic features of DKC, HHS, and cryptic DKC among Japanese patients. We analyzed 16 patients diagnosed with DKC, three patients with HHS, and 15 patients with cryptic DKC. We found that platelet count was significantly more depressed than neutrophil count or hemoglobin value in DKC patients, and identified DKC patients with large deletions in the telomerase reverse transcriptase and cryptic DKC patients with RTEL1 mutations on both alleles. This led to some patients previously considered to have unclassifiable BMF being diagnosed with cDKC through identification of new gene mutations. It thus seems important from a clinical viewpoint to re-examine the clinical characteristics, frequency of genetic mutations, and treatment efficacy in DKC, HHS, and cDKC.

  16. Reduced muscle-fiber conduction but normal slowing after cold exposure in paramyotonia congenita

    NARCIS (Netherlands)

    Blijham, P.J.; Drost, G; Stegeman, D.F.; Zwarts, M.J.

    2008-01-01

    In this study we investigated a family with paramyotonia (PC) congenita caused by a Gly1306Val mutation in the voltage-gated sodium-channel gene SCN4A. A previous study showed that exposure to cold aggravates the muscle stiffness in patients with this mutation. However, the mechanism behind cold

  17. Trunk sway analysis to quantify the warm-up phenomenon in myotonia congenita patients.

    NARCIS (Netherlands)

    Horlings, G.C.; Drost, G.; Bloem, B.R.; Trip, J.; Pieterse, A.J.; Engelen, B.G.M. van; Allum, J.H.J.

    2009-01-01

    OBJECTIVE: Patients with autosomal recessive myotonia congenita display myotonia and transient paresis that diminish with repetitive muscle contractions (warm-up phenomenon). A new approach is presented to quantify this warm-up phenomenon under clinically relevant gait and balance tasks. METHODS:

  18. Cardiovascular and renal anomalies in Turner syndrome Anomalias cardiovasculares e renais na síndrome de Turner

    Directory of Open Access Journals (Sweden)

    Annelise Barreto Carvalho

    2010-01-01

    Full Text Available OBJECTIVE: To evaluate the frequency and type of cardiovascular (CV and renal/collecting system (R/CS abnormalities seen in a sample of patients with Turner Syndrome (TS and to verify the proportion of those anomalies detected only after diagnosis was established. METHODS: Retrospective study of 130 patients with TS diagnosed in an outpatient setting between 1989 and 2006. The mean age at diagnosis was 11.9 years. Data were obtained by personal history of CV and R/CS disorders and by results of echocardiogram and ultrasonography of the kidneys and collecting system performed after diagnosis. RESULTS: 25.6% of patients who underwent echocardiograms presented CV abnormalities. Among them, mitral regurgitation (21.4%, bicuspid aortic valve (19% and aortic coarctation (19% were the most frequent. R/CS anomalies were found in 29.3% of patients who underwent ultrasonography. Among them, duplication of the collecting system and hydronephrosis (25% each and horseshoe kidney (21.2% were the most frequent. In about 80% of cases there was no previous knowledge of these anomalies. CONCLUSION: The frequency of CV and R/CS abnormalities found in this study was similar to that of previous studies, but most were found in routine exams after TS diagnosis. Thus, early detection of associated anomalies depends on early detection of TS.OBJETIVO: Analisar a frequência e os tipos de anomalias cardiovasculares (CV e de anomalias renais ou de sistema coletor (R/SC em uma amostra de pacientes com síndrome de Turner (ST e verificar a proporção dessas anomalias que só foram detectadas após o estabelecimento do diagnóstico. MÉTODOS: Estudo retrospectivo de 130 pacientes com ST diagnosticadas em serviço ambulatorial entre 1989 e 2006. A média de idade ao diagnóstico foi 11,9 anos. Foram coletados dados sobre antecedentes pessoais de anomalias CV e R/SC e resultados de ecocardiograma e ultrassonografia de rins e vias urinárias realizados após o diagn

  19. Essays in behavioral strategy

    NARCIS (Netherlands)

    Dumas, Jean-Malik

    2016-01-01

    This dissertation is composed of three quantitative empirical essays. Using social psychology, psychology and economic theory, the first essay explores how fear of death, belief in afterlife, self-esteem and generation influence the way employees project themselves in the future of their working

  20. Essays on partial retirement

    NARCIS (Netherlands)

    Kantarci, T.

    2012-01-01

    The five essays in this dissertation address a range of topics in the micro-economic literature on partial retirement. The focus is on the labor market behavior of older age groups. The essays examine the economic and non-economic determinants of partial retirement behavior, the effect of partial

  1. Anomalias dentárias de número em pacientes ortodônticos

    Directory of Open Access Journals (Sweden)

    Priscila Ferreira Torres

    Full Text Available ResumoIntroduçãoA prevalência e a distribuição das anomalias dentárias de número variam de acordo com a população estudada.ObjetivoDeterminar a prevalência de anomalias dentárias de número, verificando-se a frequência com relação a gênero, localização e dentes mais acometidos.MétodoForam avaliadas 1.054 radiografias panorâmicas de pacientes com idade entre 5 e 30 anos, realizadas no período de janeiro a março de 2010, em uma clínica particular de diagnóstico por imagem de Teresina-PI. Foram registrados dados relativos a gênero, idade, presença ou ausência de anomalia, dente acometido e localização. Foram realizados os testes estatísticos Qui-quadrado de Pearson e Teste Binominal, para duas proporções.ResultadoA hipodontia, com prevalência de 4,9%, foi encontrada com mais frequência na maxila, não apresentando diferença entre os lados e os gêneros. Os dentes mais ausentes foram: incisivos laterais superiores e segundo pré-molar inferior. Em relação à hiperdontia, com prevalência de 4,0%, não foram observadas diferenças entre gêneros, lados e maxilares. As regiões com maior presença de supranumerários foram: distal dos terceiros molares e entre pré-molares inferiores.ConclusãoFoi observada prevalência de hipodontia de 4,9%, sendo mais comum na maxila, e de hiperdontia de 4%, não apresentando diferença entre maxilares, lados e gêneros.

  2. Anomalia megadolicobasilar: a propósito de 5 casos diagnosticados angiograficamente

    Directory of Open Access Journals (Sweden)

    Walter C. Pereira

    1977-09-01

    Full Text Available Após breves considerações sobre a sintomatologia e etiopatogenia da megadolicobasilar, são apresentados 5 casos desta anomalia vascular. Concordando com a maioria dos trabalhos sobre o assunto, a idade dos doentes desta série situava-se entre a quarta e sexta décadas da vida, apresentando todos hipertensão arterial de longa duração e aterosclerose avançada; o quadro neurológico deste doentes mostrou-se variável, tendo em comum o fato de ter se iniciado abruptamente. O estudo angiográfico do sistema vértebro-basilar foi o exame que possibilitou o diagnóstico em todos os casos.

  3. Adams-Oliver syndrome associated with cutis marmorata telangiectatica congenita and congenital cataract: a case report.

    Science.gov (United States)

    Fayol, Laurence; Garcia, Patricia; Denis, Danièle; Philip, Nicole; Simeoni, Umberto

    2006-04-01

    A female infant presented with Adams-Oliver syndrome (AOS), intrauterine growth retardation, severe cutis marmorata telangiectatica congenita, bilateral congenital cataract, and periventricular lesions. The here-reported association of bilateral congenital cataract with AOS is original. Adams-Oliver syndrome is a genetic defect that causes a vasculopathy and leads to a variety of phenotypes. This observation further supports the current understanding of the physiopathology of AOS.

  4. The role of diclofenack on inducing of aplasia cutis congenita: a case report

    OpenAIRE

    Pajaziti, Laura; Rexhepi, Syzana; Shatri-Mu?a, Ylfete; Ferizi, Mybera

    2009-01-01

    Background Aplasia cutis congenita is a disorder where e newborn child is missing skin from certain areas. It is a rare condition with no particular race or sex more at risk. May occur by itself or be associated with other physical syndromes or disorders. A classification system exists for aplasia cutis congenital consisting of 9 groups, based on the number and location of the skin defects and the presence or absence of other malformations. Causes of aplasia congenital could be heredity, tera...

  5. Myotonia congenita-associated mutations in chloride channel-1 affect zebrafish body wave swimming kinematics.

    Science.gov (United States)

    Cheng, Wei; Tian, Jing; Burgunder, Jean-Marc; Hunziker, Walter; Eng, How-Lung

    2014-01-01

    Myotonia congenita is a human muscle disorder caused by mutations in CLCN1, which encodes human chloride channel 1 (CLCN1). Zebrafish is becoming an increasingly useful model for human diseases, including muscle disorders. In this study, we generated transgenic zebrafish expressing, under the control of a muscle specific promoter, human CLCN1 carrying mutations that have been identified in human patients suffering from myotonia congenita. We developed video analytic tools that are able to provide precise quantitative measurements of movement abnormalities in order to analyse the effect of these CLCN1 mutations on adult transgenic zebrafish swimming. Two new parameters for body-wave kinematics of swimming reveal changes in body curvature and tail offset in transgenic zebrafish expressing the disease-associated CLCN1 mutants, presumably due to their effect on muscle function. The capability of the developed video analytic tool to distinguish wild-type from transgenic zebrafish could provide a useful asset to screen for compounds that reverse the disease phenotype, and may be applicable to other movement disorders besides myotonia congenita.

  6. Myotonia congenita-associated mutations in chloride channel-1 affect zebrafish body wave swimming kinematics.

    Directory of Open Access Journals (Sweden)

    Wei Cheng

    Full Text Available Myotonia congenita is a human muscle disorder caused by mutations in CLCN1, which encodes human chloride channel 1 (CLCN1. Zebrafish is becoming an increasingly useful model for human diseases, including muscle disorders. In this study, we generated transgenic zebrafish expressing, under the control of a muscle specific promoter, human CLCN1 carrying mutations that have been identified in human patients suffering from myotonia congenita. We developed video analytic tools that are able to provide precise quantitative measurements of movement abnormalities in order to analyse the effect of these CLCN1 mutations on adult transgenic zebrafish swimming. Two new parameters for body-wave kinematics of swimming reveal changes in body curvature and tail offset in transgenic zebrafish expressing the disease-associated CLCN1 mutants, presumably due to their effect on muscle function. The capability of the developed video analytic tool to distinguish wild-type from transgenic zebrafish could provide a useful asset to screen for compounds that reverse the disease phenotype, and may be applicable to other movement disorders besides myotonia congenita.

  7. Essay about nuclear right

    International Nuclear Information System (INIS)

    Puig, D.

    1994-01-01

    The present essay treat about all Uruguaian Nuclear Energy legislation. Nuclear energy history, international treaties, agreements, national programs, nuclear government politics, radiation protection regulations, wastes, radioactive materials transport, environment and safeguards has been given in this compilation

  8. Essays in energy economics

    Energy Technology Data Exchange (ETDEWEB)

    Malischek, Raimund

    2016-10-25

    This thesis presents four essays in energy economics. The first essay investigates one of the workhorse models of resource economics, the Hotelling model of an inter-temporally optimizing resource extracting firm. The Hotelling model provides a convincing theory of fundamental concepts like resource scarcity, but very few empirical validations of the model have been conducted. This essay attempts to empirically validate the Hotelling model by first expanding it to include exploration activity and market power and then using a newly constructed data set for the uranium mining industry to test whether a major resource extracting mining firm in the industry is following the theory's predictions. The results show that the theory is rejected in all considered settings. The second and third essays investigate the difference in market outcomes under spot-market based trade as compared to long-term contract based trade in oligopolistic markets with investments. The second essay investigates analytically the difference in market outcomes in an electricity market setting, showing that investments and consumer welfare may be higher under spot-market based trade than under long-term contracts. The third essay proposes techniques to solve large-scale models of this kind, empirically, by exploring the practicability of this approach in an application to the international metallurgical coal market. The final essay investigates the influence of policy uncertainty on investment decisions. With France debating the role of nuclear technology, this essay analyses how policy uncertainty regarding nuclear power in France may feature in the French and European power sector. Applying a stochastic model for the European power system, the analysis shows that the costs of uncertainty in this particular application are rather low compared to the overall costs of a nuclear phase-out.

  9. Essays in energy economics

    International Nuclear Information System (INIS)

    Malischek, Raimund

    2016-01-01

    This thesis presents four essays in energy economics. The first essay investigates one of the workhorse models of resource economics, the Hotelling model of an inter-temporally optimizing resource extracting firm. The Hotelling model provides a convincing theory of fundamental concepts like resource scarcity, but very few empirical validations of the model have been conducted. This essay attempts to empirically validate the Hotelling model by first expanding it to include exploration activity and market power and then using a newly constructed data set for the uranium mining industry to test whether a major resource extracting mining firm in the industry is following the theory's predictions. The results show that the theory is rejected in all considered settings. The second and third essays investigate the difference in market outcomes under spot-market based trade as compared to long-term contract based trade in oligopolistic markets with investments. The second essay investigates analytically the difference in market outcomes in an electricity market setting, showing that investments and consumer welfare may be higher under spot-market based trade than under long-term contracts. The third essay proposes techniques to solve large-scale models of this kind, empirically, by exploring the practicability of this approach in an application to the international metallurgical coal market. The final essay investigates the influence of policy uncertainty on investment decisions. With France debating the role of nuclear technology, this essay analyses how policy uncertainty regarding nuclear power in France may feature in the French and European power sector. Applying a stochastic model for the European power system, the analysis shows that the costs of uncertainty in this particular application are rather low compared to the overall costs of a nuclear phase-out.

  10. Avaliação da influência de substâncias fenólicas e carotenoides na anomalia do epicarpo da goiaba, "anelamento"

    Directory of Open Access Journals (Sweden)

    Taiji Watanabe

    2011-03-01

    Full Text Available A anomalia do epicarpo da goiaba, comumente relatada por agricultores e técnicos como o "anelamento juvenil da goiaba", tem causado preocupação devido à desinformação sobre o assunto. O objetivo deste estudo foi analisar quimicamente as concentrações de substâncias fenólicas e carotenoides na região do epicarpo de goiabas afetadas pelo "anelamento", visando a caracterizar essa anomalia previamente relatada. Foram analisadas substâncias fenólicas (taninos, flavonas/flavonóis, antocianinas e fenóis totais e carotenoides em epicarpos de frutos verdes e maduros de goiabeiras cv. Paluma, com e sem anomalia. O delineamento experimental adotado foi o inteiramente casualizado, sendo estabelecidos seis tratamentos com o epicarpo dos frutos maduro sem anomalia na região inferior (FMSI; frutos maduros sem injuria na região superior (FMSS; frutos verdes sem anomalia na região inferior (FVSI; frutos verdes sem anomalia na região superior (FVSS; frutos verdes com anomalia na região inferior (FVCI; frutos verdes com anomalia na região superior (FVCS. Dentre as substâncias analisadas, os carotenoides, os taninos e os fenóis totais mostram indicativos para a caracterização do anelamento. Tanto substâncias fenólicas quanto carotenoides apresentam propriedades antioxidantes e, dessa forma, poderiam estar relacionadas à defesa antioxidante causada por um fator de estresse ainda desconhecido, que promove o "anelamento" característico apresentado pelas goiabas.

  11. Essays on electricity markets

    Energy Technology Data Exchange (ETDEWEB)

    Rud, Linda

    2009-07-01

    The report covers several topics of electricity markets: The first essay, 'Selected Topics on Early Electricity Market Design in Norway' studies market design issues in establishing the market-based Norwegian electricity market. Essays 2-4 focus on issues of network congestion: 'Capacity Charges: A Price Adjustment Process for Managing Congestion in Electricity Transmission Networks' presents the capacity charge approach for managing transmission constraints in electricity networks. 'Understanding the Stochastics of Nodal Prices: Price Processes in a Constrained Network' seeks a further understanding of stochastic nodal prices processes. 'Investment Evaluation in a Constrained Electricity Network with Stochastic Nodal Price Processes' studies how the interaction of the competitive market and the capacitated network affects the evaluation of investments under uncertainty, and points out potential pitfalls of evaluation. In the last essay, 'A Newsboy Model Perspective on the Power Market: The Case of a Wind Power Producer' we discuss aspects of optimal bidding for a wind power producer. (Author)

  12. Einstein's essays in science

    CERN Document Server

    Einstein, Albert

    2009-01-01

    His name is synonymous with ""genius,"" but these essays by the renowned physicist and scholar are accessible to any reader. In addition to outlining the core of relativity theory in everyday language, Albert Einstein presents fascinating discussions of other scientific fields to which he made significant contributions. The Nobel Laureate also profiles some of history's most influential physicists, upon whose studies his own work was based.Assembled during Einstein's lifetime from his speeches and essays, this book marks the first presentation to the wider world of the scientist's accomplishme

  13. Essays in Household Finance

    DEFF Research Database (Denmark)

    Hanspal, Tobin

    This Ph.D. thesis, entitled Essays in Household Finance, analyzes the determinants and implications of investment biases, personal experiences in financial markets, and financing disruptions on households, individual investors, and entrepreneurs and small business owners. The first essay...... on risk taking is the potential bias resulting from inertia and inattention, which has been shown to be endemic in household finance. If individuals are inert or inattentive, it is difficult to establish whether changes in risk taking are caused by personal experiences or whether the change in risk taking...

  14. Prevalencia de malformaciones cardíacas congenitas en 44,985 nacimientos en Colombia§

    OpenAIRE

    Baltaxe,Erik; Zarante,Ignacio

    2006-01-01

    Objetivo: Estimar la prevalencia de malformaciones congenitas cardíacas en Colombia usando la metodología del Estudio Colaborativo Latinoamericano de Malformaciones Congenitas y hacer una descripción epidemiológica de la población estudiada. Material y métodos: Estudio prospectivo de casos y controles anidado en una cohorte que incluyó 44,985 neonatos nacidos entre junio 1 de 2001 y abril 30 de 2005 en once hospitales de Colombia. Resultados: Se reportaron 55 casos (1.2 por 1,000). Treinta y ...

  15. Essays on Character & Opportunity

    Science.gov (United States)

    Center on Children and Families at Brookings, 2014

    2014-01-01

    These essays provide richer set of writings on the philosophical, empirical and practical issues raised by a focus on character, and in particular its relationship to questions of opportunity. Each one is an intellectual pemmican: sharp and to the point. Two scholars draw attention to the gendered nature of character formation (Segal and Lexmond);…

  16. Essays in auction theory

    NARCIS (Netherlands)

    Maasland, E.

    2012-01-01

    Auction theory is a branch of game theory that considers human behavior in auction markets and the ensuing market outcomes. It is also successfully used as a tool to design real-life auctions. This thesis contains five essays addressing a variety of topics within the realm of auction theory. The

  17. Rethinking the Argumentative Essay

    Science.gov (United States)

    Schneer, David

    2014-01-01

    This article investigates the construction of the argumentative essay as it is commonly presented in academic writing textbooks and classrooms for English language learners. The author first examines the traditional three-stage structure (thesis-argument-conclusion) and then problematizes it within a genre-based approach to academic writing. He…

  18. A case of dyskeratosis congenita with primary amenorrhea and adenocarcinoma of stomach

    Directory of Open Access Journals (Sweden)

    Nandini Chakrabarti

    2011-01-01

    Full Text Available Dyskeratosis congenita (DC is a rare disease characterized by hyperpigmentation, nail dystrophy and mucous membrane abnormality. Commonly occurring in males, the patients die young usually due to bone marrow suppression. Malignancies of various descriptions have been reported in this disease, the commonest being solid tumors of head/neck (squamous cell carcinoma. We report the case of a female patient with DC, who presented to us with severe wasting and primary amenorrhea and died of carcinoma stomach in our hospital 3 weeks later.

  19. X-Linked Dyskeratosis Congenita Is Predominantly Caused by Missense Mutations in the DKC1 Gene

    OpenAIRE

    Knight, S.W.; Heiss, N.S.; Vulliamy, T.J.; Greschner, S.; Stavrides, G.; Pai, G.S.; Lestringant, G.; Varma, N.; Mason, P.J.; Dokal, I.; Poustka, A.

    1999-01-01

    Dyskeratosis congenita is a rare inherited bone marrow-failure syndrome characterized by abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia. More than 80% of patients develop bone-marrow failure, and this is the major cause of premature death. The X-linked form of the disease (MIM 305000) has been shown to be caused by mutations in the DKC1 gene. The gene encodes a 514-amino-acid protein, dyskerin, that is homologous to Saccharomyces cerevisiae Cbf5p and rat Nap57 proteins. B...

  20. Skewed X-chromosome inactivation in female carriers of dyskeratosis congenita

    Energy Technology Data Exchange (ETDEWEB)

    Devriendt, K.; Matthijs, G.; Legius, E. [Univ. Hospital Gasthuisberg, Leuven (Belgium)] [and others

    1997-03-01

    In this study, we report on a family with X-linked dyskeratosis congenita (DC). Linkage analysis with markers in the factor VIII gene at Xq28 yielded a LOD score of 2 at a recombination of 0. Clinical manifestations of DC, such as skin lesions following the Blaschko lines, were present in two obligate carrier females. Highly skewed X inactivation was observed in white blood cells, cultured skin fibroblasts, and buccal mucosa from female carriers of DC in this family. This suggests a critical role for the DC gene in bone marrow-cell and fibroblast-cell proliferation. 23 refs., 4 figs., 1 tab.

  1. Botulinum toxin in myotonia congenita: it does not help against rigidity and pain.

    Science.gov (United States)

    Dressler, Dirk; Adib Saberi, Fereshte

    2014-05-01

    Botulinum toxin (BT) is a potent local muscle relaxant with analgetic properties. Myotonia congenita (MC) is a genetic disorder producing muscle rigidity and pain. BT injected into the trapezius produced mild paresis, but no effect on rigidity and pain. There were no signs of systemic effects. Lack of BT efficacy on MC rigidity confirms its origin from muscle membrane dysfunction rather than from inappropriate neuromuscular activation. Lack of BT efficacy on pain could be caused by lack of anti-rigidity effect. It could also be due to separate non-muscular pain mechanisms unresponsive to BT.

  2. CAREM reactor thermohydraulic essays laboratory

    International Nuclear Information System (INIS)

    Horro, R.; Mazzi, R.; Rossini, A.

    1990-01-01

    The main characteristics, essays projected and the present state of the Thermohydraulic Essays Laboratory -under construction at present- prepared to meet the experimental needs resulting from a power reactor design of the CAREM type, are herein described. (Author) [es

  3. The role of diclofenack on inducing of aplasia cutis congenita: a case report.

    Science.gov (United States)

    Pajaziti, Laura; Rexhepi, Syzana; Shatri-Muça, Ylfete; Ferizi, Mybera

    2009-10-12

    Aplasia cutis congenita is a disorder where e newborn child is missing skin from certain areas. It is a rare condition with no particular race or sex more at risk. May occur by itself or be associated with other physical syndromes or disorders. A classification system exists for aplasia cutis congenital consisting of 9 groups, based on the number and location of the skin defects and the presence or absence of other malformations. Causes of aplasia congenital could be heredity, teratogenic substances, placental infarcts, intrauterine infections, ectodermal dysplasias etc. Diagnosis is made based on the clinical findings. Prognosis depends of the other organs malfunction level and lesions size. Our case was an 22 months old Albanian girl, who was recommended to dermatology for a consultation by a pediatric surgeon because of the changes she had on her parietal part of the scalp with missing hair areas. The child has stenosis congenita ani and to her was installed stoma. In order to investigate other accompanied anomalies of the disease, there are made specific consults by neurologist, orthopedist, cardiologist, nephrologists and citogenetics. It was found out a minor visual discoordination, Sy Floppy, Digiti V superductus pedis bill. Laxitas articularum generalisata. It was a great challenge for us to find out that during the first trimester of the pregnancy (unplanned pregnancy), her mother used Diclofenac. Since there is limited information regarding to teratogenic effects of diclofenac, we considered it interesting to present this case.

  4. Dental and craniofacial findings in eight miniature schnauzer dogs affected by myotonia congenita: preliminary results.

    Science.gov (United States)

    Gracis, M; Keith, D; Vite, C H

    2000-09-01

    Myotonia is a clinical sign characterized by the delay of skeletal muscle relaxation following the cessation of a voluntary activity or the termination of an electrical or mechanical stimulus. Recently, Miniature Schnauzers with myotonia congenita associated with defective chloride ion conductance across the skeletal muscle membrane were identified. Congenital myotonia in these dogs appears to follow an autosomal recessive mode of inheritance. Craniofacial and dental findings of eight Miniature Schnauzer dogs with myotonia congenita are described in the present paper. These findings include: delayed dental eruption of both deciduous and permanent dentition: persistent deciduous dentition; unerupted or partially erupted permanent teeth: crowding and rotation of premolar and or incisor teeth: missing teeth: increased interproximal space between the maxillary fourth premolar and first molar teeth: decreased interproximal space between the maxillary canine and lateral incisor teeth: inability to fully close the mouth due to malocclusion: distoclusion: and, decreased mandibular range of motion. A long narrow skull with a flattened zygomatic arch and greater mandibular body curvature were also consistent findings in the affected dogs. The small number of dogs studied prevents conclusive statements about the origin of these abnormalities, however it is interesting that only 1 of 45 unaffected Miniature Schnauzer dogs showed similar traits.

  5. Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy.

    Science.gov (United States)

    Gramatges, Maria M; Bertuch, Alison A

    2013-12-01

    Telomeres are DNA-protein structures that form a protective cap on chromosome ends. As such, they prevent the natural ends of linear chromosomes from being subjected to DNA repair activities that would result in telomere fusion, degradation, or recombination. Both the DNA and protein components of the telomere are required for this essential function, because insufficient telomeric DNA length, loss of the terminal telomeric DNA structure, or deficiency of key telomere-associated factors may elicit a DNA damage response and result in cellular senescence or apoptosis. In the setting of failed checkpoint mechanisms, such DNA-protein defects can also lead to genomic instability through telomere fusions or recombination. Thus, as shown in both model systems and in humans, defects in telomere biology are implicated in cellular and organismal aging as well as in tumorigenesis. Bone marrow failure and malignancy are 2 life-threatening disease manifestations in the inherited telomere biology disorder dyskeratosis congenita. We provide an overview of basic telomere structure and maintenance. We outline the telomere biology defects observed in dyskeratosis congenita, focusing on recent discoveries in this field. Last, we review the evidence of how telomere biology may impact sporadic aplastic anemia and the risk for various cancers. Copyright © 2013 Mosby, Inc. All rights reserved.

  6. Pictorial essay: Orbital tuberculosis

    International Nuclear Information System (INIS)

    Narula, Mahender K; Chaudhary, Vikas; Baruah, Dhiraj; Kathuria, Manoj; Anand, Rama

    2010-01-01

    Tuberculosis of the orbit is rare, even in places where tuberculosis is endemic. The disease may involve soft tissue, the lacrimal gland, or the periosteum or bones of the orbital wall. Intracranial extension, in the form of extradural abscess, and infratemporal fossa extension has been described. This pictorial essay illustrates the imaging findings of nine histopathologically confirmed cases of orbital tuberculosis. All these patients responded to antituberculous treatment

  7. Essays on Expressivism

    OpenAIRE

    Toppinen, Teemu

    2014-01-01

    This dissertation consists of five articles plus an introductory essay, the overarching goal being that of defending an expressivist view about normative thought and talk. According to expressivism, the meaning of normative sentences (e.g. 'We ought to cut down on our greenhouse gas emissions,' 'There is more to good life than enjoyment') is to be explained by their expressing broadly practical, 'desire-like,' states of mind, rather than by what they are about, or by their truth-conditions. T...

  8. Anomalias oculares em pacientes portadores de deficiência auditiva genética Ocular abnormalities in genetically deaf people

    Directory of Open Access Journals (Sweden)

    Jane Chen

    2000-12-01

    Full Text Available Introdução: Para se verificar a prevalência de anomalias oculares em indivíduos portadores de deficiência auditiva de causa genética definitiva ou suspeita, este trabalho apresenta a avaliação oftalmológica de 97 indivíduos portadores de deficiência auditiva. Pacientes e Métodos: 97 indivíduos com diagnóstico definitivo ou suspeito de causa genética para disacusia foram submetidos a exame clínico oftalmológico completo; destes, 10 foram excluídos. Resultados: 42 (48,28% dos pacientes apresentaram uma ou mais anomalias oculares, 22 (25,29% pacientes apresentaram várias anormalidades oculares e quadro clínico compatíveis com síndromes genéticas estabelecidas. Conclusões: O exame oftalmológico é importante no diagnóstico sindrômico e etiológico de alguns quadros de disacusia, pois as alterações oculares podem ser a única anomalia associada à mesma.Purpose: In order to verify the prevalence of ocular abnormalities in patients who are deaf due to genetic causes, this paper presents the visual assessment of 97 deaf patients. Methods: 97 patients with definite or suspected diagno- sis of congenital and genetic deafness underwent a complete ophthalmologic evaluation; 10 patients were excluded. Results: 42 (48.28% patients presented one or more ocular abnormalities, 22 (25.29% patients presented several abnormalities and clinical manifestations of established genetic diseases. Conclusions: The ocular abnormalities may be the only clinical manifestations associated with deafness. Therefore the ophthalmological examination is a helpful tool for the etiological diagnosis of deafness.

  9. Essays on electricity markets

    Energy Technology Data Exchange (ETDEWEB)

    Rud, Linda

    2009-07-01

    The report covers several topics of electricity markets: The first essay, 'Selected Topics on Early Electricity Market Design in Norway' studies market design issues in establishing the market-based Norwegian electricity market. Essays 2-4 focus on issues of network congestion: 'Capacity Charges: A Price Adjustment Process for Managing Congestion in Electricity Transmission Networks' presents the capacity charge approach for managing transmission constraints in electricity networks. 'Understanding the Stochastics of Nodal Prices: Price Processes in a Constrained Network' seeks a further understanding of stochastic nodal prices processes. 'Investment Evaluation in a Constrained Electricity Network with Stochastic Nodal Price Processes' studies how the interaction of the competitive market and the capacitated network affects the evaluation of investments under uncertainty, and points out potential pitfalls of evaluation. In the last essay, 'A Newsboy Model Perspective on the Power Market: The Case of a Wind Power Producer' we discuss aspects of optimal bidding for a wind power producer. (Author)

  10. E-education Essay

    Institute of Scientific and Technical Information of China (English)

    李妍

    2012-01-01

    This entry is filed under Examples and tagged e-education essay sample,free education essay example,sample education essay.So many things around us have been changed by development of technology of which education can't help being an exception.Some kinds of technology have applied to education and one of produc~ is the E-education which makes us be ableto get education wherever and whenever we want to.This feature of E-education has given us many advantages.However,there is debate between online education and ordinary education due to some of concern such as technology of E-education and students responsibility for learning.Even though some problems have heen found in E-education,it could be one of best way to get good quality education and supplement ordinary education because technology which supports online education keeps developing and there are a lot of good online course which offer good qualityeducation.

  11. Essays in microeconomics

    Science.gov (United States)

    Davies, Tim

    This dissertation consists of three essays in applied microeconomics. Each essay explores a different issue of economic interest. The essay in Chapter 2 describes an experiment designed to investigate if using assets with an intrinsic value that increases over time leads to persistent undervaluation in laboratory asset trading markets. This question has not previously been investigated by researchers. Results from ten sessions are reported. Three used assets with an intrinsic value that decreased over time. The results from these sessions are consistent with the findings by prior researchers who frequently observed price bubbles in laboratory asset trading experiments. The remaining seven sessions used assets with an intrinsic value that increased over time. In all these sessions trading generally occurred at prices below the asset's intrinsic value. In Chapter 3, in an essay co-authored with Adrian Stoian, we study road running races. Tournaments, where ordinal position determines rewards, are an important component of our economy. By studying sporting tournaments, we hope to shed light on the nature of other economically significant tournaments where data may be less readily available. We separately quantify the sorting and incentive effects of tournament prizes by employing a novel two-part model which we apply to a unique data set of road running race results. We present a counterfactual example of how a hypothetical change in prizes would be predicted to change race participation and speed. In Chapter 4, in an essay co-authored with Jedidiah Brewer and Joseph Cullen, we examine the combined effects of the locations and the brands of retail gasoline outlets in Tucson, Arizona on market prices. We apply an innovative approach to model the impact of competing gas stations that avoids limiting analysis to predetermined nearby locations. We show that increased brand diversity is associated with higher prices and that gas stations affiliated with mass

  12. ZC4H2 mutations are associated with arthrogryposis multiplex congenita and intellectual disability through impairment of central and peripheral synaptic plasticity

    NARCIS (Netherlands)

    Hirata, Hiromi; Nanda, Indrajit; van Riesen, Anne; McMichael, Gai; Hu, Hao; Hambrock, Melanie; Papon, Marie-Amélie; Fischer, Ute; Marouillat, Sylviane; Ding, Can; Alirol, Servane; Bienek, Melanie; Preisler-Adams, Sabine; Grimme, Astrid; Seelow, Dominik; Webster, Richard; Haan, Eric; MacLennan, Alastair; Stenzel, Werner; Yap, Tzu Ying; Gardner, Alison; Nguyen, Lam Son; Shaw, Marie; Lebrun, Nicolas; Haas, Stefan A.; Kress, Wolfram; Haaf, Thomas; Schellenberger, Elke; Chelly, Jamel; Viot, Géraldine; Shaffer, Lisa G.; Rosenfeld, Jill A.; Kramer, Nancy; Falk, Rena; El-Khechen, Dima; Escobar, Luis F.; Hennekam, Raoul; Wieacker, Peter; Hübner, Christoph; Ropers, Hans-Hilger; Gecz, Jozef; Schuelke, Markus; Laumonnier, Frédéric; Kalscheuer, Vera M.

    2013-01-01

    Arthrogryposis multiplex congenita (AMC) is caused by heterogeneous pathologies leading to multiple antenatal joint contractures through fetal akinesia. Understanding the pathophysiology of this disorder is important for clinical care of the affected individuals and genetic counseling of the

  13. Computação autonômica aplicada ao diagnóstico e solução de anomalias de redes de computadores

    OpenAIRE

    Alexandre de Aguiar Amaral

    2015-01-01

    Resumo: A tarefa de gerenciamento de redes tem se tornado cada vez mais desafiadora. Dentre esses desafios está o problema de diagnosticar e solucionar as anomalias. As soluções atuais não têm sido suficiente para atender os requisitos demandados para a aplicação em ambientes de rede de grande escala. Os principais motivos decorrem da falta de autonomicidade e escalabilidade. Nesta tese, os conceitos da computação autonômica e distribuída são explorados para diagnosticar e solucionar anomalia...

  14. Associated dental anomalies: case report Múltiplas anomalias dentárias associadas: caso clínico

    Directory of Open Access Journals (Sweden)

    Daniela Gamba Garib

    2005-12-01

    Full Text Available Certain human dental anomalies frequently occur together, supporting the accumulated evidence of the shared genetic control of dental developmental disturbances. The present study reports a rare and interesting case of a 12-year-old girl with an association of multiple dental abnormalities, including agenesis, tooth malposition and delayed development. The etiology and treatment planning are discussed with reference to the literature. The clinical implications of genetically controlled patterns of dental anomalies are important in the establishment of early diagnosis and appropriate orthodontic intervention.Certas anomalias dentárias humanas freqüentemente ocorrem concomitantemente, contribuindo para validar as evidências do controle genético nos distúrbios de desenvolvimento. O presente estudo relata um caso raro e interessante de uma jovem de 12 anos de idade, com associação de anormalidades dentárias múltiplas, incluindo agenesia, ectopia e atraso no desenvolvimento dentário. A etiologia e tratamento planejados são discutidos com referência à literatura. As implicações clínicas do padrão de anomalias dentárias geneticamente controladas são importantes no estabelecimento do diagnóstico precoce e de adequada intervenção ortodôntica.

  15. Three Essays on Macroeconomics

    Science.gov (United States)

    Doda, Lider Baran

    This dissertation consists of three independent essays in macroeconomics. The first essay studies the transition to a low carbon economy using an extension of the neoclassical growth model featuring endogenous energy efficiency, exhaustible energy and explicit climate-economy interaction. I derive the properties of the laissez faire equilibrium and compare them to the optimal allocations of a social planner who internalizes the climate change externality. Three main results emerge. First, the exhaustibility of energy generates strong market based incentives to improve energy efficiency and reduce CO 2 emissions without any government intervention. Second, the market and optimal allocations are substantially different suggesting a role for the government. Third, high and persistent taxes are required to implement the optimal allocations as a competitive equilibrium with taxes. The second essay focuses on coal fired power plants (CFPP) - one of the largest sources of CO2 emissions globally - and their generation efficiency using a macroeconomic model with an embedded CFPP sector. A key feature of the model is the endogenous choice of production technologies which differ in their energy efficiency. After establishing four empirical facts about the CFPP sector, I analyze the long run quantitative effects of energy taxes. Using the calibrated model, I find that sector-specific coal taxes have large effects on generation efficiency by inducing the use of more efficient technologies. Moreover, such taxes achieve large CO2 emissions reductions with relatively small effects on consumption and output. The final essay studies the procyclicality of fiscal policy in developing countries, which is a well-documented empirical observation seemingly at odds with Neoclassical and Keynesian policy prescriptions. I examine this issue by solving the optimal fiscal policy problem of a small open economy government when the interest rates on external debt are endogenous. Given an

  16. Essays on Labour Markets

    DEFF Research Database (Denmark)

    Buhai, Ioan Sebastian

    ), on modelling the arousal and persistence of occupational segregation and labour market inequalities between social subgroups (chapter 4), and respectively on characterizing the link between the firms' health and safety work environment and their financial performance (chapter 5). Each of the essays contributes...... return to seniority", with seniority the position of the worker in the tenure hierarchy of her firm, this concept establishing parsimoniously but effectively the link between the worker's fate in the labour market and her firm's fate in the product market; if network referrals are relevant for job search...... work") raises, but any other specific work health and safety practice indicators do not affect, a firm's productivity....

  17. Essay Genre in Tatar Journalism

    Directory of Open Access Journals (Sweden)

    Aigul A. Guseinova

    2017-11-01

    Full Text Available In this article, an essay is considered as a journalistic genre in the context of modern Tatar journalism. Using the example of works by contemporary authors in the Tatar-speaking periodicals of Russia, the main genre and the semantic features of this genre are studied. An essay is a publicistic form to reflect on the topical issues of Russian reality. The reproduction of a fact is not so important for an essay. An important role is played by the description of the author's impressions, reflections and emotions. The periodical press has many materials in the Tatar language in which the author's opinion, author's principle and subjective opinion are strongly expressed. In fact, during the last decades of the twentieth century and the beginning of the twenty-first century there was a surge of essays in modern journalism. Due to some political events in Russia during the early 90s of the twentieth century, it was possible to express their thoughts and speak on the urgent problems in society openly in comparison with the Soviet reality. The object of research is essayism as a kind of journalistic creativity, the subject of the study is the essay genre in Tatar journalism. The empirical basis of the work consisted of the essays from Tatar journalists, publicists and writers. Provided that the personality of an author is one of the effectiveness factors concerning the publications in the genre of essay, the essayization of texts in Tatar journalism will be increased in the future.

  18. Allogeneic Hematopoietic Cell Transplantation for Dyskeratosis Congenita: A Report of 3 Cases.

    Science.gov (United States)

    Tamura, Shinichi; Imamura, Toshihiko; Urata, Takayo; Kobayashi, Miki; Gen, Mari; Tomii, Toshihiro; Do, Junko; Osone, Shinya; Ishida, Hiroyuki; Hosoi, Hajime; Kuroda, Hiroshi

    2017-10-01

    Although bone marrow failure in patients with dyskeratosis congenita (DKC) can be successfully treated with allogeneic hematopoietic cell transplantation (allo-HCT) using a reduced intensity conditioning (RIC) regimen, the outcome of nonhematological disorders in patients with DKC treated with allo-HCT using RIC has not been fully elucidated. Here, we describe the clinical course of nonhematological disorders after allo-HCT with RIC in 3 consecutive patients with DKC. Allo-HCT with RIC was feasible in all cases; however, patient 1 developed lethal pulmonary disease and patient 2 experienced progression of hepatic fibrosis. Careful follow-up of patient-specific complications is required after allo-HCT in patients with DKC.

  19. A Rare Form of Corneal Opacity Associated with Spondyloepiphyseal Dysplasia Congenita

    Directory of Open Access Journals (Sweden)

    Yuichiro Ishida

    2018-02-01

    Full Text Available A 13-year-old Japanese female diagnosed with spondyloepiphyseal dysplasia congenita (SEDC was referred for ophthalmologic evaluation. Examination with slit-lamp and optical coherence tomography revealed bilateral thin cornea with diffuse corneal opacity which was localised at the posterior stromal depth in the central cornea. Unlike the two previously reported cases of diffuse and nodular patterns of corneal opacity in SEDC, the current case exhibited a rare form of corneal opacity. SEDC is one of the type II collagenopathies, characterised by dwarfism because the mutations in COL2A1 prevent bone growth. Although the existence of type II collagen has not been reported in the human corneal stroma, the aetiology of the opacity in the corneal stroma in SEDC type II collagenopathy is of interest.

  20. Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.

    Science.gov (United States)

    Duverger, Olivier; Carlson, Jenna C; Karacz, Chelsea M; Schwartz, Mary E; Cross, Michael A; Marazita, Mary L; Shaffer, John R; Morasso, Maria I

    2018-01-01

    Pachyonychia congenita (PC) is a cutaneous disorder primarily characterized by nail dystrophy and painful palmoplantar keratoderma. PC is caused by mutations in KRT6A, KRT6B, KRT6C, KRT16, and KRT17, a set of keratin genes expressed in the nail bed, palmoplantar epidermis, oral mucosal epithelium, hair follicle and sweat gland. RNA-seq analysis revealed that all PC-associated keratins (except for Krt6c that does exist in the mouse genome) are expressed in the mouse enamel organ. We further demonstrated that these keratins are produced by ameloblasts and are incorporated into mature human enamel. Using genetic and intraoral examination data from 573 adults and 449 children, we identified several missense polymorphisms in KRT6A, KRT6B and KRT6C that lead to a higher risk for dental caries. Structural analysis of teeth from a PC patient carrying a p.Asn171Lys substitution in keratin-6a (K6a) revealed disruption of enamel rod sheaths resulting in altered rod shape and distribution. Finally, this PC-associated substitution as well as more frequent caries-associated SNPs, found in two of the KRT6 genes, that result in p.Ser143Asn substitution (rs28538343 in KRT6B and rs151117600 in KRT6C), alter the assembly of K6 filaments in ameloblast-like cells. These results identify a new set of keratins involved in tooth enamel formation, distinguish novel susceptibility loci for tooth decay and reveal additional clinical features of pachyonychia congenita.

  1. X-linked adrenal hypoplasia congenita: a case report and ethical dilemma.

    Science.gov (United States)

    Ismail, Heba M; Rincon, Marielisa

    2014-07-01

    Our objective is to present the first case report of X-linked adrenal hypoplasia congenita in a child conceived by a donated egg and which also presented atypically, with initial mineralocorticoid deficiency. Case report with literature review. A late preterm fraternal twin male, conceived by in vitro fertilization of donated eggs, presented shortly after birth with feeding intolerance, hyponatremia, and hyperkalemia. Testing revealed a low aldosterone level, high plasma renin activity, normal cortisol level, and normal 17-hydroxyprogesterone level. He was diagnosed with 18-hydroxylase deficiency based on low 18-hydroxycorticosterone levels and was treated with mineralocorticoid successfully for 17 months. At age 18 months, he presented with dehydration secondary to herpetic gingivostomatitis and was found to be hypoglycemic, hyponatremic, hyperkalemic, and acidotic, with a low serum cortisol level. An adrenocorticotropic hormone (ACTH) stimulation test revealed low levels of all adrenal cortex products, with an elevated ACTH level. He was started on glucocorticoids. Genetic testing confirmed X-linked adrenal hypoplasia congenita (AHC). His asymptomatic fraternal twin underwent genetic testing and the results were negative. The fertility center records indicated that the mother had donated eggs to other families, but none of the children were known to have this disorder. The egg donor was informed but did not pursue genetic testing. We report a case of X-linked AHC presenting in the context of extraordinary ethical considerations. Our case raises a question unique to the era of assisted reproduction: should routine genetic screening of gamete donors be done for rare but potentially life-threatening conditions?

  2. Essays on Stock Issuance

    DEFF Research Database (Denmark)

    Kohl, Niklas

    Firms which issue new equity subsequently have lower returns than other firms, but does the strength of the issuance effect vary in the cross section of firms? The essay shows, that US firms with characteristics that makes them “hard to value” have returns which are strongly related to their past...... issuance activity, while the return of “easy to value” firms are less related to their past issuance activity. In most cases the difference between “hard to value” and “easy to value” firms are signiffcant. As proxies for “hard to value”, I use three different types of firm characteristics. First, I...... consider firms for which relatively little information is available as “hard to value”. Examples are firms covered by few analysts and small firms. Second, I consider firms with high levels of analyst disagreement on stock price target, next quarter earnings per share and share recommendation as “hard...

  3. Writing a pictorial essay.

    Science.gov (United States)

    Peh, W C G; Ng, K H

    2010-03-01

    A pictorial essay is a type of educational article that aims to provide both textual and visual portrayals of a topical issue. It usually consists of a short unstructured abstract, brief introduction, subheadings to organise the material and a summary. The number of references is limited to a few key articles, typically, eight to 15, or fewer. The text is usually short, often approximately 1,000 to 2,000 words in length, with much of the message contained in the figure legends. This type of article allows for a large number of figures, typically up to 20 figures or 30 figure parts. The main criteria for publication are currency, educational value and high quality of illustrations.

  4. Essays on Housing Markets

    DEFF Research Database (Denmark)

    Bäckman, Claes

    In Denmark and in many countries around the world, housing markets are of considerable importance for households and policy-makers alike. As the boom and bust in the US and Danish housing market so aptly demonstrated, disruptions in the housing market potentially have wide-ranging consequences...... for individual households and for the aggregate economy. Housing is important because we all have to live somewhere, but also because it serves as a considerable source of both wealth and debt. As such, housing market policy can not only create vast benefits for many, but can also have substantial negative...... impacts for all, and should therefore be a topic of major interest for economists and policy makers alike. This Ph.D. thesis, entitled “Essays on Housing Markets”, analyzes the Danish housing market during the 2000s, with a focus on how policy changes affected house prices and how changes in house prices...

  5. Myotonia congenita

    Science.gov (United States)

    ... trouble swallowing in an infant Long-term (chronic) joint problems Weakness of the abdominal muscles When to ... A.M. Editorial team. Muscle Disorders Read more Neuromuscular Disorders Read more NIH MedlinePlus Magazine Read more ...

  6. Myotonia Congenita

    Science.gov (United States)

    ... the disorder. Additional research is focused on developing animal models of the disorder to test potential treatments and therapies. Information from the National Library of Medicine’s MedlinePlus ...

  7. Atrichia congenita

    Directory of Open Access Journals (Sweden)

    Marfatia Y

    1991-01-01

    Full Text Available Three sisters aged 10, 13 and 14, presented with absence of scalp and facial hair. The youngest sister had scalp hair at birth, but had hair fall later, while the other two did not have hair at birth. Three other siblings had normal long hair, and there was no family history of any similar condition. Examination showed complete absence of scalp, axillary and pubic hair in all the three sisters.

  8. Essays in applied microeconomics

    Science.gov (United States)

    Davis, Lucas William

    2005-11-01

    The first essay measures the impact of an outbreak of pediatric leukemia on local housing values. A model of residential location choice is used to describe conditions under which the gradient of the hedonic price function with respect to health risk is equal to household marginal willingness to pay to avoid pediatric leukemia risk. This equalizing differential is estimated using property-level sales records from a county in Nevada where residents have recently experienced a severe increase in pediatric leukemia. Housing values are compared before and after the increase with a nearby county acting as a control group. The results indicate that housing values decreased 15.6% during the period of maximum risk. Results are similar for alternative measures of risk and across houses of different sizes. With risk estimates derived using a Bayesian learning model the results imply a statistical value of pediatric leukemia of $5.6 million. The results from the paper provide some of the first market-based estimates of the value of health for children. The second essay evaluates the cost-effectiveness of public incentives that encourage households to purchase high-efficiency durable goods. The demand for durable goods and the demand for energy and other inputs are modeled jointly as the solution to a household production problem. The empirical analysis focuses on the case of clothes washers. The production technology and utilization decision are estimated using household-level data from field trials in which participants received front-loading clothes washers free of charge. The estimation strategy exploits this quasi-random replacement of washers to derive robust estimates of the utilization decision. The results indicate a price elasticity, -.06, that is statistically different from zero across specifications. The parameters from the utilization decision are used to estimate the purchase decision using data from the Consumer Expenditure Survey, 1994-2002. Households

  9. Plagiarism in residency application essays.

    Science.gov (United States)

    Segal, Scott; Gelfand, Brian J; Hurwitz, Shelley; Berkowitz, Lori; Ashley, Stanley W; Nadel, Eric S; Katz, Joel T

    2010-07-20

    Anecdotal reports suggest that some residency application essays contain plagiarized content. To determine the prevalence of plagiarism in a large cohort of residency application essays. Retrospective cohort study. 4975 application essays submitted to residency programs at a single large academic medical center between 1 September 2005 and 22 March 2007. Specialized software was used to compare residency application essays with a database of Internet pages, published works, and previously submitted essays and the percentage of the submission matching another source was calculated. A match of more than 10% to an existing work was defined as evidence of plagiarism. Evidence of plagiarism was found in 5.2% (95% CI, 4.6% to 5.9%) of essays. The essays of non-U.S. citizens were more likely to demonstrate evidence of plagiarism. Other characteristics associated with the prevalence of plagiarism included medical school location outside the United States and Canada; previous residency or fellowship; lack of research experience, volunteer experience, or publications; a low United States Medical Licensing Examination Step 1 score; and non-membership in the Alpha Omega Alpha Honor Medical Society. The software database is probably incomplete, the 10%-match threshold for defining plagiarism has not been statistically validated, and the study was confined to applicants to 1 institution. Evidence of matching content in an essay cannot be used to infer the applicant's intent and is not sensitive to variations in the cultural context of copying in some societies. Evidence of plagiarism in residency application essays is more common in international applicants but was found in those by applicants to all specialty programs, from all medical school types, and even among applicants with significant academic honors. No external funding.

  10. Olivier's 'Essay on Hamlet'

    Directory of Open Access Journals (Sweden)

    Koprivica Zoran

    2017-01-01

    Full Text Available Laurence Olivier's Hamlet is more a renaissance character, a melancholic and a daydreamer, than a man of action, unlike his Henry V and Richard III film adaptations. However, it seems that Olivier showed outstanding courage not in his extremely liberal approach to interpreting this Shakespeare's tragedy, but in literal application of Freud's model on his inner problems, seen through the prism of the professor Ernest Johnson. Transposing Shakespeare's original text, starting with its global features, he abstracts numerous and diversified eventful and associative moments which might burden the polyphonic structure of his own - film story. Moreover, Olivier wants to avoid its dramatic deconstruction and focuses the viewer's attention to the climactic moments. However, dramatically the strongest and most effective scenes in his film adaptation of Hamlet are the ones related to the use of camera, that is to say, its movement and analyticity. The intention was to point not only to the ostentatious difference between cinematographic and theatrical stylisation, but, to a certain extent, he defines the viewer's standpoint. In his 'essay on Hamlet', Olivier does not consider chronology, that is to say, the problem of temporal relations. The visual structure of the film and its dynamics are determined a priori by the rhythmic parameters of the Elsinore's labyrinthic space.

  11. Review Essay: Controlled Openness

    Directory of Open Access Journals (Sweden)

    Andreas Wenninger

    2008-08-01

    Full Text Available The book reviewed here contains a written form of Niklas LUHMANN’s last lecture, delivered in winter term 1992/1993 at Bielefeld University, where he was professor for sociology from 1968 to 1993. A more comprehensive and systematic publication titled "Die Gesellschaft der Gesellschaft" was not published until 1997. In comparison to this and to other publications the present one provides an insight into the modality of the theoretical practice of LUHMANN. My review-essay follows up that point and reminds us that LUHMANN worked out his theory of society in view of a sociological problem he had conceived. He accused sociology of accumulating knowledge in a confusing way by empirical social research. His endeavour, in contrast, was to enable research within a consistent theoretical frame that was nevertheless open to expansive explorations. LUHMANN tries to achieve consistency through the reciprocal adjustment of his terms and his theoretical components, which should enable the construction of problems for comparison within global society. This means that his approach stays open for an empirical reality that remains to be explored because the theory of society does not deliver terms to categorize empirical reality. Instead, terms are conceptualized as distinctions with the function to construct problems that instruct observations and make them amenable to theorization. URN: urn:nbn:de:0114-fqs0803237

  12. Rhombencephalitis: pictorial essay

    Directory of Open Access Journals (Sweden)

    Líllian Gonçalves Campos

    Full Text Available Abstract The term rhombencephalitis refers to inflammatory diseases affecting the hindbrain (brainstem and cerebellum. Rhombencephalitis has a wide variety of etiologies, including infections, autoimmune diseases, and paraneoplastic syndromes. Infection with bacteria of the genus Listeria is the most common cause of rhombencephalitis. Primary rhombencephalitis caused by infection with Listeria spp. occurs in healthy young adults. It usually has a biphasic time course with a flu-like syndrome, followed by brainstem dysfunction; 75% of patients have cerebrospinal fluid pleocytosis, and nearly 100% have an abnormal brain magnetic resonance imaging scan. However, other possible causes of rhombencephalitis must be borne in mind. In addition to the clinical aspects, the patterns seen in magnetic resonance imaging can be helpful in defining the possible cause. Some of the reported causes of rhombencephalitis are potentially severe and life threatening; therefore, an accurate initial diagnostic approach is important to establishing a proper early treatment regimen. This pictorial essay reviews the various causes of rhombencephalitis and the corresponding magnetic resonance imaging findings, by describing illustrative confirmed cases.

  13. Essays on medieval computational astronomy

    CERN Document Server

    Bergón, José Chabás

    2014-01-01

    In Essays on Medieval Computational Astronomy the authors provide examples of original and intelligent approaches and solutions given by medieval astronomers to the problems of their discipline, mostly presented in the form of astronomical tables.

  14. Evidências de Anomalias Ósseas em Stahleckeria potens Huene, 1935 (Therapsida, Anomodontia.

    Directory of Open Access Journals (Sweden)

    Cibele Schwanke

    2007-07-01

    processo inflamatório,provavelmente associado às depressões descritas, o que reforça a idéia de que tais anomalias ósseas tenham sido ocasionadas durante a vida do animal. O segundo espécime (DGM 155-R apresenta umaextensa área claramente desgastada, formando epífise proximal e se prolonga até o início da diáfise, aparentemente resultante da fossildiagênese. Uma análise mais detalhada desta depressão nos permite observar além das perdas tafonômicas, estruturasque sugerem a existência de um remodelamento ósseo, que pode ter atingindo grande parte da região cortical do osso. Em áreas associadas a esta egião, encontram-se indícios de remodelamento doperiósteo, caracterizado por estrutura óssea irregular, sugerindo a existência de algum processo traumático ou infeccioso. Dessa forma, é possível inferir que esta alteração esteja associada a um processo de inflamação óssea gerado por infecções, distensões musculares ou fraturas em outros membros ou ossos da mesma pata, que possam ter afetado a postura e a locomoção do animal. Assim, considera-se que odesgaste pós-morte local tenha sido facilitado pela presença de uma estrutura mais fragilizada do osso remodelado nesta região.

  15. Three essays on economic development

    OpenAIRE

    Méndez Errico, Paula Luciana

    2014-01-01

    The main objective of this dissertation is to study some of the mechanisms suggested by the economic literature as factors that could prevent individuals from attaining certain domains of well-being. This thesis is divided in three independent essays providing new evidence on three issues within the field of economic development: the effect of social networks on immigrants' labor market outcomes (first essay), the long-lasting impact of income inequality on entrepreneurial success and job cre...

  16. ULTRASOUND GUIDED ILIOINGUINAL AND ILIOHYPOGASTRIC NERVE BLOCK FOR INGUINAL HERNIA REPAIR IN ARTHROGRYPOSIS MULTIPLEX CONGENITA

    Directory of Open Access Journals (Sweden)

    Paul O.

    2015-06-01

    Full Text Available Arthrogryposis multiplex congenita (AMC refers to a syndrome of unknown etiology with multiple congenital contractures in one or more joints with a concomitant inability of passive extension and flexion . The overall prevalence of arthrogryposis is one in 3000 live births . The extensive contractures , tense skin , minimal muscle mass and subcutaneous tissue pose challenges in anaesthetic management. We report a seven year old boy (15 kg , known case of AMC with congenital talipes equino varus (CTEV and bilateral hip dislocation posted for right sided herniot omy and orchidopexy. We planned to combine general anaesthesia without muscle relaxants and regional nerve block. The child was induced with propofol and Classic LMA Size 2 was inserted. An ilioinguinal and i liohypogastric nerve block was given under ultrasound guidance using 0.2% ropivacaine. Pateint remained hemodynamically stable during surgery with minimal anaesthetic requirement and no anlgesics. Analgesia lasted for 8 hours postoperatively. Combining narcosis with regional anaesthesia leads to a reduced demand for anaesthetics , stable circulatory conditions , maintenance of spontaneous breathing , prevention of stress and sufficient postoperative analgesia

  17. Adrenal hypoplasia congenita: a rare cause of primary adrenal insufficiency and hypogonadotropic hypogonadism

    Directory of Open Access Journals (Sweden)

    Marta Loureiro

    2015-09-01

    Full Text Available Primary adrenal insufficiency is defined by the impaired synthesis of adrenocortical hormones due to an intrinsic disease of the adrenal cortex. Determining its etiology is crucial to allow adequate long-term management and genetic counseling. We report the case of a male adolescent that presented in the neonatal period with adrenal crisis and received replacement therapy for primary adrenal insufficiency. During follow-up, adrenal hypoplasia congenita (AHC was suspected given his persistently raised adrenocorticotropic hormone levels, with markedly low 17-OH progesterone and androstenedione levels. DNA sequence analysis revealed a mutation in NR0B1 gene (c.1292delG, confirming the diagnosis. Delayed puberty and persistent low levels of gonadotropins led to testosterone replacement therapy. X-linked AHC is a rare cause of primary adrenal insufficiency and hypogonadotropic hypogonadism, related to mutations in NR0B1 gene. Despite its rarity, AHC should be considered in patients who present with primary adrenal failure, low levels of 17-OH progesterone and hypogonadotropic hypogonadism.

  18. A novel mutation in CLCN1 associated with feline myotonia congenita.

    Directory of Open Access Journals (Sweden)

    Barbara Gandolfi

    Full Text Available Myotonia congenita (MC is a skeletal muscle channelopathy characterized by inability of the muscle to relax following voluntary contraction. Worldwide population prevalence in humans is 1:100,000. Studies in mice, dogs, humans and goats confirmed myotonia associated with functional defects in chloride channels and mutations in a skeletal muscle chloride channel (CLCN1. CLCN1 encodes for the most abundant chloride channel in the skeletal muscle cell membrane. Five random bred cats from Winnipeg, Canada with MC were examined. All cats had a protruding tongue, limited range of jaw motion and drooling with prominent neck and proximal limb musculature. All cats had blepharospasm upon palpebral reflex testing and a short-strided gait. Electromyograms demonstrated myotonic discharges at a mean frequency of 300 Hz resembling the sound of a 'swarm of bees'. Muscle histopathology showed hypertrophy of all fiber types. Direct sequencing of CLCN1 revealed a mutation disrupting a donor splice site downstream of exon 16 in only the affected cats. In vitro translation of the mutated protein predicted a premature truncation and partial lack of the highly conserved CBS1 (cystathionine β-synthase domain critical for ion transport activity and one dimerization domain pivotal in channel formation. Genetic screening of the Winnipeg random bred population of the cats' origin identified carriers of the mutation. A genetic test for population screening is now available and carrier cats from the feral population can be identified.

  19. Yeast artificial chromosome cloning in the glycerol kinase and adrenal hypoplasia congenita region of Xp21

    Energy Technology Data Exchange (ETDEWEB)

    Worley, K.C.; Ellison, K.A.; Zhang, Y.H.; Wang, D.F.; Mason, J.; Roth, E.J.; Adams, V.; Fogt, D.D.; Zhu, X.M.; Towbin, J.A. [Baylor College of Medicine, Houston, TX (United States)] [and others

    1993-05-01

    The adrenal hypoplasia congenita (AHC) and glycerol kinase (GK) loci are telomeric to the Duchenne muscular dystrophy locus in Xp21. The authors developed a pair of yeast artificial chromosome (YAC) contigs spanning at least 1.2 Mb and encompassing the region from the telomeric end of the Duchenne muscular dystrophy (DMD) locus to beyond YHX39 (DXS727), including the genes for AHC and GK. The centromeric contig consists of 13 YACs reaching more than 600 kb from DMD through GK. The telomeric contig group consists of 8 YACs containing more than 600 kb including the markers YHX39 (DXS727) and QST-59 (DXS319). Patient deletion breakpoints in the region of the two YAC contigs define at least eight intervals, and seven deletion breakpoints are contained within these contigs. In addition to the probes developed from YAC ends, they have mapped eight Alu-PCR probes amplified from a radiation-reduced somatic cell hybrid, two anonymous DNA probes, and one Alu-PCR product amplified from a cosmid end, for a total of 26 new markers within this region of 2 Mb or less. One YAC in the centromeric contig contains an insert encompassing the minimum interval for GK deficiency defined by patient deletion breakpoints, and this clone includes all or part of the GK gene. 33 refs., 3 figs., 5 tabs.

  20. Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita.

    Science.gov (United States)

    Ballew, Bari J; Yeager, Meredith; Jacobs, Kevin; Giri, Neelam; Boland, Joseph; Burdett, Laurie; Alter, Blanche P; Savage, Sharon A

    2013-04-01

    Dyskeratosis congenita (DC) is an inherited bone marrow failure and cancer predisposition syndrome caused by aberrant telomere biology. The classic triad of dysplastic nails, abnormal skin pigmentation, and oral leukoplakia is diagnostic of DC, but substantial clinical heterogeneity exists; the clinically severe variant Hoyeraal Hreidarsson syndrome (HH) also includes cerebellar hypoplasia, severe immunodeficiency, enteropathy, and intrauterine growth retardation. Germline mutations in telomere biology genes account for approximately one-half of known DC families. Using exome sequencing, we identified mutations in RTEL1, a helicase with critical telomeric functions, in two families with HH. In the first family, two siblings with HH and very short telomeres inherited a premature stop codon from their mother who has short telomeres. The proband from the second family has HH and inherited a premature stop codon in RTEL1 from his father and a missense mutation from his mother, who also has short telomeres. In addition, inheritance of only the missense mutation led to very short telomeres in the proband's brother. Targeted sequencing identified a different RTEL1 missense mutation in one additional DC proband who has bone marrow failure and short telomeres. Both missense mutations affect the helicase domain of RTEL1, and three in silico prediction algorithms suggest that they are likely deleterious. The nonsense mutations both cause truncation of the RTEL1 protein, resulting in loss of the PIP box; this may abrogate an important protein-protein interaction. These findings implicate a new telomere biology gene, RTEL1, in the etiology of DC.

  1. Essays in Applied Microeconomics

    Science.gov (United States)

    Ge, Qi

    This dissertation consists of three self-contained applied microeconomics essays on topics related to behavioral economics and industrial organization. Chapter 1 studies how sentiment as a result of sports event outcomes affects consumers' tipping behavior in the presence of social norms. I formulate a model of tipping behavior that captures consumer sentiment following a reference-dependent preference framework and empirically test its relevance using the game outcomes of the NBA and the trip and tipping data on New York City taxicabs. While I find that consumers' tipping behavior responds to unexpected wins and losses of their home team, particularly in close game outcomes, I do not find evidence for loss aversion. Coupled with the findings on default tipping, my empirical results on the asymmetric tipping responses suggest that while social norms may dominate loss aversion, affect and surprises can result in freedom on the upside of tipping. Chapter 2 utilizes a novel data source of airline entry and exit announcements and examines how the incumbent airlines adjust quality provisions as a response to their competitors' announcements and the role of timing in such responses. I find no evidence that the incumbents engage in preemptive actions when facing probable entry and exit threats as signaled by the competitors' announcements in either short term or long term. There is, however, evidence supporting their responses to the competitors' realized entry or exit. My empirical findings underscore the role of timing in determining preemptive actions and suggest that previous studies may have overestimated how the incumbent airlines respond to entry threats. Chapter 3, which is collaborated with Benjamin Ho, investigates the habit formation of consumers' thermostat setting behavior, an often implicitly made decision and yet a key determinant of home energy consumption and expenditures. We utilize a high frequency dataset on household thermostat usage and find that

  2. Essays in public economics

    Science.gov (United States)

    Seligman, Jason Scott

    2002-01-01

    Three essays in the field of public economics are included in this thesis. Chapter 1 begins this work with an introduction to public economics and places the remaining chapters in context. Like all economic agents, the government must manage its cash position. Chapter 2 considers this activity. Short-term financial requirements cause the government to solicit the market for bills not previously scheduled (Cash Management Bills). Using data from the US Treasury's Proprietary Domestic Finance Database, this chapter shows that these bills have higher costs than normal bills, suggesting that both Treasury and financial markets appreciate that demand is more inelastic for these instruments. In addition, this research identifies several factors that increase finance costs for Treasury in meeting short-term financial need. Chapter 3 explores location choices for generation investment in a re-regulated electricity market. Recently, there have been significant changes in the regulation of electricity in the State of California. These changes may affect generation investment behavior within the State, an important consideration for policy makers. This work identifies the impact of public sector regulatory change on private sector investment outcomes, by comparing the location and scope of electricity generation projects before and after two specific regulatory changes in air quality management and transmission tariff charges, while controlling for expected population growth patterns within the State. Significant changes in location preference are identified using factors for the northern and southern transmission zones, NP15 and SP15, the intermediate zone ZP26, and for areas outside of ISO control. Chapter 4 considers Disability Insurance and individual public pension investment accounts. Current debate on the Social Security Administration's long-term finance of benefits includes proposals for independent private investment via individual accounts. The author investigates

  3. Geração de mapas de anomalia Bouguer a partir de dados gravimétricos terrestres e do EGM2008

    Directory of Open Access Journals (Sweden)

    Gilberto Gagg

    2017-05-01

    Full Text Available Um dos propósitos da determinação da gravidade é a obtenção das anomalias da gravidade. O campo de gravidade é um campo potencial e sofre influência da constituição geológica, pois a densidade das rochas gera pequenas variações nos valores de gravidade. As reduções matemáticas buscam eliminar a influência de fatores que interferem no campo de gravidade. A anomalia Bouguer remove o efeito gravitacional das rochas existentes entre o ponto de observação e o nível de referência. Dados da missão gravimétrica GRACE (Gravity Recovery and Climate Experiment tem auxiliado na densificação das informações, pois muitos modelos geopotenciais são deficientes devido a irregular distribuição dos dados gravimétricos. Assim, efetuou-se um estudo para o estado do Rio Grande do Sul-RS, visando gerar mapas de anomalia Bouguer através de uma análise gravimétrica sob dois aspectos: uso exclusivo de dados do modelo EGM2008 (envolve uso de dados GRACE, e uso combinado de dados EGM2008 (porção oceânica e porção continental externa ao RS com dados terrestres de campo para o Rio Grande do Sul. Concluiu-se que o emprego de dados de missão satelitais facilmente acessíveis, permitiu gerar mapas de anomalias Bouguer que atendem objetivos de cunho geral e até regional, com a vantagem de serem atuais e uniformemente espaçados.

  4. Estenose aórtica supravalvar em adulto com anomalia de vasos da base e insuficiência aórtica

    Directory of Open Access Journals (Sweden)

    Acrisio Sales Valente

    2013-12-01

    Full Text Available A estenose aórtica supravalvar é uma rara cardiopatia congênita, bastante incomum em adultos. Apresentamos um caso de estenose aórtica supravalvar em adulto com anomalia de vasos do arco aórtico, já com presença de insuficiência aórtica importante, tratado com êxito por meio de plastia da aorta ascendente e troca valvar aórtica.

  5. Anomalia de Ebstein: resultados com a reconstrução cônica da valva tricúspide

    Directory of Open Access Journals (Sweden)

    Silva José Pedro da

    2004-01-01

    Full Text Available OBJETIVO: Analisar os resultados de uma modificação técnica de plastia da valva tricúspide na anomalia de Ebstein. MÉTODOS: De novembro/1993 a agosto/2002, 21 pacientes com anomalia de Ebstein da valva tricúspide, com idades variando de 20 meses a 37 (média: 23 anos, foram submetidos a uma nova técnica de plastia da valva tricúspide, onde o megafolheto anterior tricúspide é desinserido da parede ventricular e do anel valvar, total, ou quase totalmente, transformando-o num cone, cujo vértice permanece fixo na ponta do ventrículo direito e cuja base é suturada ao verdadeiro anel tricúspide, inclusive na região septal, após o ajuste, com uma plicatura do anel, ao tamanho da base do cone. RESULTADOS: Houve um (4,7%, óbito hospitalar, causado por baixo débito cardíaco em portador de miocardiopatia causada pela hipóxia crônica. O tempo médio de seguimento foi de 4 anos e os ecocardiogramas recentes mostraram boa morfologia do ventrículo direito e valva tricúspide com discreta ou mínima insuficiência em 18 pacientes e moderada em 2. Em dois dos três portadores de feixe anômalo foi possível localizá-los e seccioná-los no ato cirúrgico. Não ocorreu bloqueio atrioventricular em nenhum dos pacientes. CONCLUSÃO: A técnica utilizada foi eficiente para a correção da insuficiência tricúspide e a restauração da morfologia do ventrículo direito, e aplicável para todos os tipos anatômicos de Ebstein, exceto o tipo D da classificação de Carpentier.

  6. Diagnóstico prenatal de artrogriposis múltiple congénita Prenatal diagnosis of arthrogryposis multiplex congenita

    Directory of Open Access Journals (Sweden)

    Ivonne Martínez Vidal

    2013-03-01

    Full Text Available La artrogriposis múltiple congénita puede definirse como una displasia articular sistémica, caracterizada por rigidez articular en múltiples localizaciones de forma congénita. Se presenta un caso en el que se diagnosticó prenatalmente este signo clínico, que puede tener múltiples causas subyacentes.Arthrogryposis multiplex congenita may be defined as a systemic articular dysplasia characterized by articular rigidity in a many locations of congenital origin. A case was presented in which this clinical sign was diagnosed at prenatal phase and it may have many underlying causes.

  7. Essays on numbers and figures

    CERN Document Server

    Prasolov, V V

    2000-01-01

    This is the English translation of the book originally published in Russian. It contains 20 essays, each dealing with a separate mathematical topic. The topics range from brilliant mathematical statements with interesting proofs, to simple and effective methods of problem-solving, to interesting properties of polynomials, to exceptional points of the triangle. Many of the topics have a long and interesting history. The author has lectured on them to students worldwide. The essays are independent of one another for the most part, and each presents a vivid mathematical result that led to current

  8. Scrapbook (a visual essay

    Directory of Open Access Journals (Sweden)

    Jonathan Carson

    2011-08-01

    Full Text Available

    Abstract: Working with a range of material (objects, ephemera, texts characteristic of a scrapbook, Carson & Miller will produce a visual essay that investigates the experience of reading such matter in this often underrated and undervalued form. In this context the notion of reading (and, subsequently re-reading and mis-reading will be utilised to explore the construction of narrative and the manner in which such narratives can present misleading, misinterpreted or inaccurate accounts of ‘things’. In doing so, such accounts can produce a multiplicity of new narratives.

                To develop this idea visually Carson & Miller will harness the tradition and format of a scrapbook. Scrapbooks imply the creative use of material which would be valued differently (or indeed undervalued in other contexts; the inclusion of scraps in the scrapbook claims that which is defined as ‘scrap’ as valuable and worthy of possession. In essence a scrapbook brings together disparate material and is often constructed according to its own internal ordering and logic; sometimes things are related by type, sometimes unlikely objects are combined or juxtaposed in fortuitous encounters. Such fortuitous encounters tell their own stories but also produce new narratives through generating new combinations of significance (Allmer iv.

  9. Spondyloepiphseal dysplasia congenita in siblings born to unaffected parents: ? germ line mosaicism

    Energy Technology Data Exchange (ETDEWEB)

    Mulla, W.; McDonald-McGinn, D.; Zackai, E. [Univ. of Pennsylvania School of Medicine, Philadelphia, PA (United States)] [and others

    1994-09-01

    Germ line mosaicism has been used to explain the birth of more than one child affected with a dominantly inherited disorder born to unaffected parents. Furthermore, it has been confirmed clinically in families where recurrence in siblings was originally thought to be autosomal recessive, but were affected individuals have reproduced affected offspring. Firm evidence of germ line mosaicism using mutation analysis by molecular methods exists for some autosomal disorders. We present two siblings with spondyloepipheseal dysplasia congenita (SEDC) born to unaffected parents. This suggests the presence of germ line mosaicism in this entity. Patient 1 was born at 32 weeks gestation to a G1P1 Puerto Rican mother. The pregnancy was complicated by polyhydramnios. The neonate, a short-limbed dwarf, died at 15 hours of age from respiratory distress and a compromised thoracic cavity. Patient 2, the sibling of patient 1 was born at 37 weeks gestation after a pregnancy complicated by polyhydramnios and prenatal ultrasound diagnosis of short-limbed dwarfism. The diagnosis of SEDC was made and, after review of the sibling`s postmortem X-rays, it was felt that she was similarly affected. The family history reveals no history of dwarfism or consanguinity. The SEDC is described as an autosomal dominant form of dwarfism with variable presentation including some cases that have been lethal in the neonatal period. SEDC is now believed to represent a family of collagen II mutations. Sporadic cases that have arisen in families with no history have been ascribed to new heterozygous mutations. Other families in which SEDC and SEMD recurred without a family history most likely represent germ line mosaicism. In these cases molecular studies should be pursued to document a collagen II mutation. We believe that germ line mosaicism is the most plausible explanation for recurrence in our family.

  10. Familial athrogryposis multiplex congenita in Gusau, Nigeria: Case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Bilkisu Ilah Garba

    2017-01-01

    Full Text Available Arthrogryposis multiplex congenita (AMC is characterized by contractions of multiple joints present at birth with fat or fibrous tissue partially or totally replacing muscles. The etiology is from the interplay of genetic and environmental factors. A 2-day-old male term neonate presented with a history of multiple contractures in all limbs since birth, fever, and vomiting of 1-day duration. An older sibling, a male child had similar multiple contractures in all limbs and died a few days after birth. A maternal aunt had a male child with multiple contractures of all limbs who also died a few days after birth. Parents are young and not related. Our case had multiple contractures and specific posture involving all the limbs; however no cardiac or neurological abnormality was observed. He was managed as a case of neonatal sepsis with AMC (likely X-linked with antibiotics and had plaster of Paris applied on the lower limbs. He did well and was discharged home to be followed up at the clinic. He, however, did not come for follow-up and died at home at the age of 10 weeks. Arthrogryposis is a common congenital presentation which requires comprehensive musculoskeletal evaluation and genetic consultation. Early rehabilitation requires the involvement of the parents or guardians and a multidisciplinary approach. This is to optimize possibility of making a diagnosis and providing parents with accurate information regarding the likelihood of recurrence. However, accurate information on recurrence is only possible when the cause of the AMC in any patient/family under investigation is identified.

  11. Loss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita

    NARCIS (Netherlands)

    Xue, Shifeng; Maluenda, Jérôme; Marguet, Florent; Shboul, Mohammad; Quevarec, Loïc; Bonnard, Carine; Ng, Alvin Yu Jin; Tohari, Sumanty; Tan, Thong Teck; Kong, Mung Kei; Monaghan, Kristin G.; Cho, Megan T.; Siskind, Carly E.; Sampson, Jacinda B.; Rocha, Carolina Tesi; Alkazaleh, Fawaz; Gonzales, Marie; Rigonnot, Luc; Whalen, Sandra; Gut, Marta; Gut, Ivo; Bucourt, Martine; Venkatesh, Byrappa; Laquerrière, Annie; Reversade, Bruno; Melki, Judith

    2017-01-01

    Arthrogryposis multiplex congenita (AMC) is a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. Through genetic mapping of disease loci and whole-exome sequencing in four unrelated multiplex families presenting with severe AMC, we

  12. Essays in Education and Macroeconomics

    Science.gov (United States)

    Herrington, Christopher M.

    2013-01-01

    This dissertation consists of three essays on education and macroeconomics. The first chapter analyzes whether public education financing systems can account for large differences among developed countries in earnings inequality and intergenerational earnings persistence. I first document facts about public education in the U.S. and Norway, which…

  13. Essays on financial market integration

    NARCIS (Netherlands)

    Pungulescu, C.

    2009-01-01

    The four essays in this dissertation address these main questions and alternate a general perspective with focused analysis on specific measures of integration and regions, providing several novel answers. First, new relevant proxies are proposed to measure financial market integration. They give

  14. Essays on mergers and acquisitions

    NARCIS (Netherlands)

    Faelten, A.I.

    2016-01-01

    Essays on Mergers and Acquisitions" tackles some of the most prominent business challenges related to M&A activity. The Introduction examines the reasons why deals fail through well-known case studies; Chapter 1 presents a new index measuring countries M&A maturity worldwide; Chapter 2 focus on the

  15. Dance for two selected essays

    CERN Document Server

    Lightman, Alan

    1996-01-01

    The author of Einstein's Dreams now presents a collection of essays, written over the past 20 years, that displays his genius for bringing literary and scientific concerns into ringing harmony. Sometimes provocative, sometimes fanciful, always elegantly conceived and written, these meditations offer readers a fascinating look into the creative compulsions shared by the scientist and the artist. Reading tour.

  16. Demise of the essay question.

    OpenAIRE

    Tombleson, P.

    1990-01-01

    Psychometric studies of the essay paper in 1988 showed this instrument to have unacceptably low levels of reliability and generalizability. Furthermore, factor analysis showed that the paper's perceived functions could not be supported statistically. It was decided to discontinue the paper and introduce a replacement which would reflect the line of development envisaged by the College in the 1990s.

  17. Essays in industrial organization and management strategy

    OpenAIRE

    de Bijl, P.W.J.

    1996-01-01

    This thesis contains five essays in the theory of industrial organization and management strategy. An introduction makes the main ideas accessible to non-specialists by presenting the essays as fictitious cases. The first essay investigates strategic disclosure of verifiable information. The disclosed information concerns a hidden action, and the transmission of information takes place in a noisy environment. The second essay explores how search costs and informational asymmetries influence t...

  18. Essays on Economic Volatility and Financial Frictions

    OpenAIRE

    Zhao, Hongyan

    2012-01-01

    This dissertation consists of three essays in macroeconomics. The first one essay discusses the reasons of Chinese huge foreign reserves holdings. It contributes to the literature of sudden stops, precautionary saving and foreign assets holdings. In the second essay, I study the price volatility of commodities and manufactured goods. I measure the price volatility of each individual goods but not on the aggregated level and therefore the results complete the related study. The third essay exp...

  19. Self-Assessment in Coursework Essays.

    Science.gov (United States)

    Longhurst, Nigel; Norton, Lin S.

    1997-01-01

    Self-assessments of coursework essays were compared with tutor grades for 67 college students. Students could accurately assess their overall essay grades and could give an overall rank for deep processing, but when judging essays on individual criteria they were not so accurate when compared to tutor evaluations. (SLD)

  20. Essays in industrial organization and management strategy

    NARCIS (Netherlands)

    de Bijl, P.W.J.

    1996-01-01

    This thesis contains five essays in the theory of industrial organization and management strategy. An introduction makes the main ideas accessible to non-specialists by presenting the essays as fictitious cases. The first essay investigates strategic disclosure of verifiable information. The

  1. Essays on Dynamic Competition and Academic Entrepreneurship

    Science.gov (United States)

    Pham, Huyen T.

    2012-01-01

    My dissertation focuses on dynamic firm competition and academic entrepreneurship. The first essay studies the dynamics and equilibrium outcomes of a duopoly in which firms make decisions about both capacity expansion and cost reduction. The second essay is an extension of the framework used in the first essay to study the strategic roles of…

  2. Anomalia anorretal e cuidados maternos Anormalidades anorectales y la atención materna Anorectal anomaly and maternal care

    Directory of Open Access Journals (Sweden)

    Manuela Costa Melo

    2011-02-01

    Full Text Available O objetivo deste artigo foi realizar um estudo de revisão bibliográfica sobre anomalia anorretal e cuidados maternos. O assunto foi abordado por meio de revisão integrativa realizada em consulta de artigos publicados nas bases de dados indexados na Biblioteca Virtual em Saúde. Foram identificadas 25 publicações que atenderam aos critérios de inclusão e exclusão pré-estabelecidos. Nos estudos analisados observaram-se distintos desenhos metodológicos demonstrando que algumas crianças nascidas com anomalia anorretal necessitam de cirurgia de urgência. Os profissionais de saúde, juntamente aos pais, precisam desenvolver parcerias que possibilitem um acompanhamento a longo prazo e orientações cuidadosas. Faz-se necessário que novas pesquisas sejam realizadas sobre o tema, com propostas metodológicas que retratem melhor a essência do cuidado com as crianças estomizadasEl objetivo de este artículo fue realizar un estudio de revisión bibliográfica sobre anomalía ano retal y cuidados maternos. El asunto fue abordado por medio de una revisión integral realizada por consulta de artículos publicados en las bases de datos indexados en la Biblioteca Virtual en Salud. Fueron identificadas 25 publicaciones que atendieron a los criterios de inclusión y exclusión pre-establecidos. En los estudios analizados se observaron distintos dibujos metodológicos demostrando que algunos niños nacidos con anomalía ano retal necesitan de cirugía de urgencia. Los profesionales de salud, juntamente con los padres, necesitan desarrollar grupos que posibiliten un acompañamiento a largo plazo y orientaciones cuidadosas. Se hace necesario que nuevos estudios sean realizados sobre el tema, con propuestas metodológicas que retraten mejor la esencia del cuidado con los niños con ostomíaThis purpose of the article was to make a bibliographic review about anorectal malformations and maternal cares. The matter was addressed through an integrative

  3. Essays on liberalized energy markets

    Energy Technology Data Exchange (ETDEWEB)

    Nese, Gjermund

    2003-07-01

    This thesis consists of four essays that aim at contributing to the understanding of some of the new challenges associated by the liberalized energy markets. More specifically the essays consider investments in energy generation projects; international trade of Green Certificates, market power in a Green Certificate system, and finally the behaviour of public firms in liberalized markets. Essay 1 considers energy investment, when a choice has to be made between fossil fuel and biomass fired production technologies. A dynamic model is presented to illustrate the effect of the different degrees of input price uncertainty on the choice of technology and the timing of the investment. It is shown that when the choice of technology is irreversible, it may be optimal to postpone the investment even if it would otherwise be optimal to invest in one or both of the plant types. We provide a numerical example based on cost estimates of two different power plant types. Essay 2 presents an analytical equilibrium model for simultaneously functioning international markets for electricity and Green Certificates is formulated. The percentage requirement is perceived as the policy instrument affecting the level of green electricity in end-use consumption. In none of the cases considered does an increase in the country's percentage requirement necessarily result in an increase in the generation of green electricity in that country, but it may have a positive effect on the trading partner's generation of green electricity. Further, under quite realistic assumptions, a country maximizes its generation of green electricity by setting the percentage requirement to zero. In essay 3 an analytic equilibrium model for a simultaneously functioning electricity market and a market for Green Certificates is formulated. The major focus of the paper is the effect of market power in a Green Certificate system. One of the main results is that the certificate system faced with market power

  4. Essays on liberalized energy markets

    International Nuclear Information System (INIS)

    Nese, Gjermund

    2003-01-01

    This thesis consists of four essays that aim at contributing to the understanding of some of the new challenges associated by the liberalized energy markets. More specifically the essays consider investments in energy generation projects; international trade of Green Certificates, market power in a Green Certificate system, and finally the behaviour of public firms in liberalized markets. Essay 1 considers energy investment, when a choice has to be made between fossil fuel and biomass fired production technologies. A dynamic model is presented to illustrate the effect of the different degrees of input price uncertainty on the choice of technology and the timing of the investment. It is shown that when the choice of technology is irreversible, it may be optimal to postpone the investment even if it would otherwise be optimal to invest in one or both of the plant types. We provide a numerical example based on cost estimates of two different power plant types. Essay 2 presents an analytical equilibrium model for simultaneously functioning international markets for electricity and Green Certificates is formulated. The percentage requirement is perceived as the policy instrument affecting the level of green electricity in end-use consumption. In none of the cases considered does an increase in the country's percentage requirement necessarily result in an increase in the generation of green electricity in that country, but it may have a positive effect on the trading partner's generation of green electricity. Further, under quite realistic assumptions, a country maximizes its generation of green electricity by setting the percentage requirement to zero. In essay 3 an analytic equilibrium model for a simultaneously functioning electricity market and a market for Green Certificates is formulated. The major focus of the paper is the effect of market power in a Green Certificate system. One of the main results is that the certificate system faced with market power may

  5. Anomalias oculares e características genéticas na síndrome de Marfan

    Directory of Open Access Journals (Sweden)

    Sallum Juliana Maria Ferraz

    2002-01-01

    Full Text Available Objetivo: Para se identificar as alterações oculares presentes na síndrome de Marfan, este trabalho apresenta a avaliação oftalmológica de 46 indivíduos portadores desta doença. Métodos: Estudo prospectivo com avaliação clínica de 46 pacientes portadores de síndrome de Marfan com avaliação oftalmológica completa. Dezessete pacientes também foram submetidos a exame genético clínico e estudo molecular. Resultados: Dos quarenta e seis pacientes incluídos neste estudo, as seguintes alterações oculares foram encontradas com maior freqüência: subluxação do cristalino (67,3%, hipoplasia de íris (23,9%, descolamento de retina (7,6%, córnea plana (2,2%, megalocórnea (2,2% e miopia ou astigmatismo miópico (34,8%. Cinco pacientes (10,9% apresentaram exame ocular normal em ambos os olhos. Detectou-se uma mutação patogênica distinta das relatadas na literatura em uma paciente, uma mutação de sentido trocado que ocorreu no éxon 28 levando à mudança de aminoácido C1166Y. Conclusões: As alterações oculares da síndrome de Marfan são freqüentes e o conhecimento do gene responsável FBN-1 e de sua expressão no olho auxiliam para o diagnóstico e tratamento destas anomalias.

  6. Essays on Entrepreneurship and Innovation

    OpenAIRE

    Queiro, Francisco

    2015-01-01

    These essays investigate the role of entrepreneurial human capital as a driver of innovation and growth. In the first chapter, I estimate the effect of manager education on firm employment growth using administrative panel data on the universe of firms in Portugal between 1995 and 2009. I exploit manager changes and switches between management and other occupations to account for unobserved firm and manager characteristics as well as selection into management. I find that a year of manager sc...

  7. Three essays in risky behaviors

    OpenAIRE

    Sampaio, Mafalda

    2012-01-01

    A PhD Dissertation, presented as part of the requirements for the Degree of Doctor of Philosophy from the NOVA - School of Business and Economics This dissertation consists of three essays on the relationship between risky behaviors and social environment, including the strategic construction of conversational networks to discuss HIV related issues, the impact of social stigma on risky behaviors, and how subjective expectations from parents can influence childhood obesity. Underst...

  8. Essays in Empirical Asset Pricing

    DEFF Research Database (Denmark)

    Rzeznik, Aleksandra

    This thesis consists of three essays investigating financial and real estate markets and identifying a relationship between them. A 2008 financial crises provides a perfect example of sizeable interactions between US housing market and equity prices, where a negative shock to house prices trigger...... a word-wide recession. Therefore, understanding forces driving investors behaviour and preferences, which in turn affect asset prices in both equity and housing market are of great interest....

  9. Five essays in property valuation

    OpenAIRE

    Yang, Zan

    2000-01-01

    This doctoral thesis consists of five self-contained essayspresented to the Faculty Board of the Royal Institute ofTechnology. Property valuation is a central issue that forms acommon thread in the analysis in these essays. In the thesisproperty is considered in a mixed asset context in an attemptto build a bridge between valuation, property investment andfinancial theory. The object of the thesis is to value propertyfor finance, sales and purchases and investment. Theinvestigation of the the...

  10. Anomalia de Peters, seus aspectos clínicos e terapêuticos: relato de caso Peter's anomaly, clinical and therapeutic aspects: case report

    Directory of Open Access Journals (Sweden)

    Isadora Meyer

    2010-08-01

    Full Text Available A anomalia de Peters consiste na mais comum opacidade corneana congênita e é secundária à malformação do segmento anterior do olho. Suas principais características são opacidade corneana central e sinéquias da íris e/ou do cristalino com a região do leucoma. Pode apresentar-se de forma isolada ou associada a outras anomalias oculares e sistêmicas, tendo prognóstico mais sombrio nestes casos. A etiologia da anomalia Peters permanece incerta, sendo aventadas causas genéticas, infecciosas, traumáticas e tóxicas. O tratamento varia com a apresentação do quadro, sendo importante a pronta detecção da doença, possibilitando o tratamento precoce, com bom desenvolvimento da visão. Este trabalho relata um caso de anomalia de Peters diagnosticado tardiamente e discute as características da doença e possibilidades de tratamento.Peter's anomaly consists in the most common congenital corneal opacity related to a malformation of the anterior segment of the eye. Its main characteristics are central leukoma and iridocorneal adherences at the area affected by the leukoma. It can be identified isolated or in association with other ocular or systemic abnormalities, and the prognostic tend to be worse in the latter cases. The etiology of Peter's anomaly remains uncertain, but the most likely causes are related to genetic, infectious, traumatic and toxic factors. A range of possible treatment strategies exists, though the effectiveness of each of them depends on how the disease occurs and whether it is identified in early or advanced stages - the earlier the diagnosis, the higher the possibility of a successful intervention, given that precocious treatments are more likely to result in a good development of the vision. This work reports a case of Peter's anomaly that was diagnosed in an advanced stage, discussing the characteristics of the case and treatment possibilities.

  11. Essay

    Science.gov (United States)

    Xu, Shuping

    2018-05-01

    Professor Yukihiro Ozaki has made great impacts in the spectroscopy communities all over the world. Throughout his career, he has established strong collaborations and communications with scientists from Asian countries, which solidified his grand academic stature in the field of molecular spectroscopy. In the past years, he has been pushing forward the development of spectroscopy in many Asian countries, particularly to China. Since his first trip to China in 1994, he has visited China almost 40 times. Under his continuous efforts during these years, deep and long-term collaborations with several universities and research institutes in China were established. Prof. Ozaki was endowed with honorary professorships in numerous institutes and universities in China including Jilin University and Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. He has been a visiting professor of many Chinese universities including Shanghai JiaoTong University, Hunan University, Central South University, Peking University, East China Normal University, and Beijing University of Chemical Technology. Great friendships have been established between him and his Chinese colleagues as a result of mutual respect and common scientific interests. Prof. Ozaki is an expert in various facets of spectroscopy including two-dimensional correlation spectroscopy, polymer material science, deep-UV and near infrared spectroscopy, chemometrics, and surface-enhanced Raman spectroscopy. Over the past decades, Prof. Ozaki has contributed greatly to training the Chinese youth scientists: 11 doctoral students, 16 post-doctoral researchers and 9 guest-professors and 17 visiting scholars from China have been studied/worked in his research group. He is not only a historical witness for the development of molecular spectroscopy in China, but also a creator. He has served on the editorial board of several Chinese journals such as the Journal of Light Scattering, Spectroscopy and Spectral Analysis, Journal of Near Infrared and Millimeter Waves, etc. He has coauthored more than 200 publications with Chinese researchers. Owing to his great contributions to the spectroscopy research of China, Prof. Ozaki has been awarded Changbai Mountain Friendship Award, the highest honor from Jilin Province, China in 2010 and China Friendship Award on Molecular Spectroscopy, from the Chinese Optical Society in 2016. Prof. Ozaki is a trustworthy and respected mentor, as well as a meritorious friend for Chinese spectroscopic scientists. His outstanding contributions to the field of spectroscopy in China is already a shining hallmark to Prof. Ozaki's career and will be remembered by all who follow.

  12. Osteopathia striata congenita with cranial sclerosis and intellectual disability due to contiguous gene deletions involving the WTX locus

    DEFF Research Database (Denmark)

    Holman, Sk; Morgan, T; Baujat, G

    2013-01-01

    Osteopathia striata congenita with cranial sclerosis (OSCS) is a skeletal dysplasia caused by germline deletions of or truncating point mutations in the X-linked gene WTX (FAM123B, AMER1). Females present with longitudinal striations of sclerotic bone along the long axis of long bones and cranial...... sclerosis, with a high prevalence of cleft palate and hearing loss. Intellectual disability or neurodevelopmental delay is not observed in females with point mutations in WTX leading to OSCS. One female has been described with a deletion spanning multiple neighbouring genes suggesting that deletion of some...... neighbouring loci may result in abnormal neurodevelopment. In this cohort of 13 females with OSCS resulting from deletions of WTX, a relationship is observed where deletion of ARHGEF9 and/or MTMR8 in conjunction with WTX results in an additional neurodevelopmental phenotype whereas deletion of ASB12 along...

  13. Art and Pornography: Philosophical Essays

    OpenAIRE

    2012-01-01

    Art and Pornography presents a series of essays\\ud which investigate the artistic status and aesthetic\\ud dimension of pornographic pictures, films, and\\ud literature, and explores the distinction, if there is\\ud any, between pornography and erotic art. Is there\\ud any overlap between art and pornography, or are\\ud the two mutually exclusive? If they are, why is\\ud that? If they are not, how might we characterize\\ud pornographic art or artistic pornography, and how\\ud might pornographic art b...

  14. A philosophical essay on probabilities

    CERN Document Server

    Laplace, Marquis de

    1996-01-01

    A classic of science, this famous essay by ""the Newton of France"" introduces lay readers to the concepts and uses of probability theory. It is of especial interest today as an application of mathematical techniques to problems in social and biological sciences.Generally recognized as the founder of the modern phase of probability theory, Laplace here applies the principles and general results of his theory ""to the most important questions of life, which are, in effect, for the most part, problems in probability."" Thus, without the use of higher mathematics, he demonstrates the application

  15. Essays on mergers and acquisitions

    OpenAIRE

    Faelten, A.I.

    2016-01-01

    Essays on Mergers and Acquisitions" tackles some of the most prominent business challenges related to M&A activity. The Introduction examines the reasons why deals fail through well-known case studies; Chapter 1 presents a new index measuring countries M&A maturity worldwide; Chapter 2 focus on the importance of corporate governance when conducting deals in unknown territories; whilst Chapter 3 and 4 conduct research on companies’ decision to tap capital markets and their subsequent M&A acti...

  16. Essays on Customization Applications in Marketing

    OpenAIRE

    Adiguzel, Feray

    2006-01-01

    The primary objective of this thesis is to develop and validate new methodologies to improve the collection of data and the effectiveness of promotion customization. This thesis contains two essays. In these essays, we search for optimal combinations of components of questionnaires to design split questionnaires and product categories to offer promotions. The first essay deals with how to improve collection of data. We focus on split questionnaires to collect data instead of using the more ty...

  17. DNA Damage and Oxidative Stress in Dyskeratosis Congenita: Analysis of Pathways and Therapeutic Stategies Using CPISPR and iPSC Model Systems

    Science.gov (United States)

    2017-06-01

    via p53. Together, this evidence suggests that ROS may be causative towards establishing a senescent state in a short-telomere background. Little ...attrition facilitates entry into senescence. Keywords (limit to 20 words ) Dyskeratosis congenita, bone marrow failure, aging, telomere...Results Dissemination Data from this project has been presented publicly at the American Society of Hematology (ASH) in December of 2015 as a poster

  18. Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients

    OpenAIRE

    Gu, Bai-Wei; Apicella, Marisa; Mills, Jason; Fan, Jian-Meng; Reeves, Dara A.; French, Deborah; Podsakoff, Gregory M.; Bessler, Monica; Mason, Philip J.

    2015-01-01

    Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized by the presence of short telomeres at presentation. Mutations in ten different genes, whose products are involved in the telomere maintenance pathway, have been shown to cause DC. The X-linked form is the most common form of the disease and is caused by mutations in the gene DKC1, encoding the protein dyskerin. Dyskerin is required for the assembly and stability of telomerase and is also involved in ribosom...

  19. IMAGENES EN ANOMALIAS ANORECTALES

    OpenAIRE

    Moënne B, Karla

    2003-01-01

    Las malformaciones anorectales incluyen una amplia variedad de anomalías, de grados variables de complejidad, que con frecuencia se presentan asociadas a otras malformaciones: genitourinarias, espinales, cardíacas, esofágicas y de la pared abdominal entre las más habituales. Las imágenes diagnósticas tienen un importante rol en el estudio de estos pacientes, que está orientado a demostrar adecuadamente la anatomía de la malformación y, por otra parte, precisar la existencia de anomalías asoci...

  20. Anomalias dentárias associadas: o ortodontista decodificando a genética que rege os distúrbios de desenvolvimento dentário Associated dental anomalies: the orthodontist decoding the genetics which regulates the dental development disturbances

    Directory of Open Access Journals (Sweden)

    Daniela Gamba Garib

    2010-04-01

    Full Text Available O presente trabalho versa sobre o diagnóstico e a abordagem ortodôntica das anomalias dentárias, enfatizando os aspectos etiológicos que definem tais irregularidades de desenvolvimento. Parece existir uma inter-relação genética na determinação de algumas dessas anomalias, considerando-se a alta frequência de associações. Um mesmo defeito genético pode originar diferentes manifestações fenotípicas, incluindo agenesias, microdontias, ectopias e atraso no desenvolvimento dentário. As implicações clínicas das anomalias dentárias associadas são muito relevantes, uma vez que o diagnóstico precoce de uma determinada anomalia dentária pode alertar o clínico sobre a possibilidade de desenvolvimento de outras anomalias associadas no mesmo paciente ou em outros membros da família, permitindo a intervenção ortodôntica em época oportuna.This article aims to approach the diagnosis and orthodontic intervention of the dental anomalies, emphasizing the etiological aspects which define these developmental irregularities. It seems to exist a genetic inter-relationship determining some dental anomalies, considering the high frequency of associations. The same genetic defect may give rise to different phenotypes, including tooth agenesis, microdontia, ectopias and delayed dental development. The clinical implications of the associated dental anomalies are relevant, since early detection of a single dental anomaly may call the attention of professionals to the possible development of other associated anomalies in the same patient or in the family, allowing timely orthodontic intervention.

  1. Essays on Customization Applications in Marketing

    NARCIS (Netherlands)

    Adiguzel, Feray

    2006-01-01

    The primary objective of this thesis is to develop and validate new methodologies to improve the collection of data and the effectiveness of promotion customization. This thesis contains two essays. In these essays, we search for optimal combinations of components of questionnaires to design split

  2. Essays on preference formation and home production

    NARCIS (Netherlands)

    Xu, Yan

    2017-01-01

    This thesis consists of three essays in quantitative marketing, focusing on structural empirical analysis of the evolution of consumer brand preference under incomplete information and the effect of time on consumer purchase behavior. The first essay studies the evolution of consumer brand

  3. Constitution 200: A Bicentennial Collection of Essays.

    Science.gov (United States)

    Hepburn, Mary A., Ed.; And Others

    Constitutional essays which formed the basis of public assemblies throughout three states are compiled in this book. The first three essays consider the U.S. government principles of federalism, judicial review, and the separation of powers. Michael L. Benedict proposes that the question of ultimate sovereignty has been answered differently by…

  4. Essays on top management and corporate behavior

    NARCIS (Netherlands)

    Wu, H.T.

    2010-01-01

    Human behavior is fascinating, and there is no exception to what its influences are on the financial market. This dissertation consists of three essays that examine corporate behavior that is affected by decisions made by the top management. The first essay studies the rationale for leveraged buyout

  5. Audiotape Feedback for Essays in Distance Education

    NARCIS (Netherlands)

    Kirschner, P.A.; Brink, H. van den; Meester, M.

    1991-01-01

    Students who were required to write three short essays for a university level course on photochemistry at the Open university of the Netherlands received either audio-cassette or written feedback on their essays. The students receiving the audio feedback described their experience as personal,

  6. Essays on financial structure and macroeconomic performance

    NARCIS (Netherlands)

    Zhu, D.

    2006-01-01

    In addressing the matter, two essays study the effects of the debt vs. equity dimension of the financial structure on international consumption smoothing and macroeconomic volatility (in particular, economic downturns). Another essay evaluates the role of informal financial institution by looking

  7. Essays in financial reporting, tax, and politics

    NARCIS (Netherlands)

    Janssen, W.H.P.

    2015-01-01

    This dissertation contains three essays on financial reporting, tax, and politics. The first essay explores whether the tax authority is able to generate spillover effects for auditors. The IRS can generate spillover effects for auditors, as a strong IRS increases manager’s incentives to comply with

  8. Essays on Industrial Organization and Political Economy

    Science.gov (United States)

    Camara, Odilon Roberto VG de a

    2009-01-01

    This thesis presents three essays on industrial organization and political economy. In the first essay, I show how the attributes of a managerial workforce affect firms' placement decisions and wage offers, and managers' quit decisions. My OLG model features two division managers and a CEO, where each executive may be at a different point in his…

  9. How Reflective Is the Academic Essay?

    Science.gov (United States)

    Maclellan, Effie

    2004-01-01

    The purpose of this study was to examine the extent of reflection in academic essays. Forty essays, all previously deemed to be of merit quality, were analysed in terms of three elements of reflection--how the educational issue is conceptualized; what the issue means for practice; and how practice might be changed to resolve the problematic. Each…

  10. Three essays on access pricing

    Science.gov (United States)

    Sydee, Ahmed Nasim

    In the first essay, a theoretical model is developed to determine the time path of optimal access price in the telecommunications industry. Determining the optimal access price is an important issue in the economics of telecommunications. Setting a high access price discourages potential entrants; a low access price, on the other hand, amounts to confiscation of private property because the infrastructure already built by the incumbent is sunk. Furthermore, a low access price does not give the incumbent incentives to maintain the current network and to invest in new infrastructures. Much of the existing literature on access pricing suffers either from the limitations of a static framework or from the assumption that all costs are avoidable. The telecommunications industry is subject to high stranded costs and, therefore, to address this issue a dynamic model is imperative. This essay presents a dynamic model of one-way access pricing in which the compensation involved in deregulatory taking is formalized and then analyzed. The short run adjustment after deregulatory taking has occurred is carried out and discussed. The long run equilibrium is also analyzed. A time path for the Ramsey price is shown as the correct dynamic price of access. In the second essay, a theoretical model is developed to determine the time path of optimal access price for an infrastructure that is characterized by congestion and lumpy investment. Much of the theoretical literature on access pricing of infrastructure prescribes that the access price be set at the marginal cost of the infrastructure. In proposing this rule of access pricing, the conventional analysis assumes that infrastructure investments are infinitely divisible so that it makes sense to talk about the marginal cost of investment. Often it is the case that investments in infrastructure are lumpy and can only be made in large chunks, and this renders the marginal cost concept meaningless. In this essay, we formalize a model of

  11. Clinical heterogeneity in a family with DKC1 mutation, dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome in first cousins

    Directory of Open Access Journals (Sweden)

    Cristina Olivieri

    2017-10-01

    Full Text Available Dyskeratosis congenita (DC is an inherited bone marrow failure disorder characterized by mucocutaneous features (skin pigmentation, nail dystrophy and oral leukoplakia, pulmonary fibrosis, hematologic and solid malignancies. Its severe form, recognized as Hoyeraal-Hreidarsson syndrome (HHS, also includes cerebellar hypoplasia, microcephaly, developmental delay and prenatal growth retardation. In literature phenotypic variability among DC patients sharing the same mutation is wellknown. To our knowledge this report describes for the first time a family of DC patients, characterized by a member with features of classic DC and another one with some features of HHS, both with the same mutation in DKC1. Our family confirms again that one mutation can be associated with different phenotypes and different hematological manifestations. It’s possible to speculate that there are likely to be patients who do not clinically fit neatly into either classical DC or HHS, but whose clinical features are due to mutations in DKC1 or in genes responsible for autosomal DC/HHS.

  12. The Gulf War: A Critical Essay

    National Research Council Canada - National Science Library

    Tzu, Sun

    1992-01-01

    This essay, written by the famous Chinese military theoretician, Sun Tzu, proposes a thesis that ought to provoke considerable discussion among theoreticians in training at the National War College...

  13. Transforming the Reserve Component: Four Essays

    National Research Council Canada - National Science Library

    Binnendijk, Hans; Baranick, Michael J; Bell, Raymond E., Jr; Cordero, Gina; Duncan, Stephen M; Holshek, Christopher; Wentz, Larry

    2005-01-01

    This volume contains four essays on various aspects of the Reserve Component. We publish it at a time when Reserves are serving overseas at historically high rates and when new missions like homeland security demand their attention...

  14. Transforming the Reserve Component: Four Essays

    National Research Council Canada - National Science Library

    Binnendijk, Hans; Baranick, Michael J; Bell, Raymond E., Jr; Cordero, Gina; Duncan, Stephen M; Holshek, Christopher; Wentz, Larry

    2005-01-01

    .... The first essay calls for a fundamental restructuring of the Reserve Component in light of the largest mobilization since the Korean War, which has been fraught with problems in terms of combat...

  15. Guidelines for writing an argumentative essay

    OpenAIRE

    Aleksandra Egurnova

    2014-01-01

    The guidelines below are intended for teachers, professors, students, and the public at large who are interested in the issues of English writing culture. They provide a detailed plan for completing the writing task–writing an argumentative essay.

  16. Essays on the theory of numbers

    CERN Document Server

    Dedekind, Richard

    1963-01-01

    Two classic essays by great German mathematician: one provides an arithmetic, rigorous foundation for the irrational numbers, the other is an attempt to give the logical basis for transfinite numbers and properties of the natural numbers.

  17. Three essays on utility regulation

    Science.gov (United States)

    Hlasny, Vladimir

    To induce utilities in the gas distribution market to operate efficiently, US states have deployed consumer choice programs, price caps, and variations of sliding scale plans. My first essay studies the impact of these restructuring and deregulation efforts on consumer rates, using panel data from a custom survey of state commissions and the Department of Energy. I estimate the residential, small commercial and industrial price equations jointly, and use instrumental variables to control for the potentially endogenous demand and status of deregulation. Consumer choice programs lower the prices by 2.2-20.1% compared to the rate of return regulation, benefiting industrial consumers the most and households the least. These effects appear even one to two years prior to the programs' implementation, and become stronger over time. Price caps lower all prices by 0.0-20.0%, with the same ranking. The impacts of sliding scale plans are close to zero, between -2.6% and +4.0% The second paper evaluates health damages caused by air concentrations of SO2 under three alternative environmental policies leading to identical aggregate emissions: emission caps, a nationwide emission tax, and a system of tradable emission allowances such as the one currently used in the US. The numerical model of the industry finds generators' output, participation in energy trade and SO2 abatement effort under each policy. The resulting SO2 concentrations are used to derive the aggregate health damages using estimates in the medical literature. SO2 concentrations vary across policies even when the aggregate emissions are the same. These variations translate into substantially different losses for any individual state, and, nationwide, to hundreds of millions of dollars of difference in aggregate damages. Emission caps are found to lead to the lowest damages, outperforming the currently used system of allowances by 452 million. A uniform emission tax leads to very similar damages as the system of

  18. Two Essays in Financial Economics

    Science.gov (United States)

    Putnam, Kyle J.

    The following dissertation contains two distinct empirical essays which contribute to the overall field of Financial Economics. Chapter 1, entitled "The Determinants of Dynamic Dependence: An Analysis of Commodity Futures and Equity Markets," examines the determinants of the dynamic equity-commodity return correlations between five commodity futures sub-sectors (energy, foods and fibers, grains and oilseeds, livestock, and precious metals) and a value-weighted equity market index (S&P 500). The study utilizes the traditional DCC model, as well as three time-varying copulas: (i) the normal copula, (ii) the student's t copula, and (iii) the rotated-gumbel copula as dependence measures. Subsequently, the determinants of these various dependence measures are explored by analyzing several macroeconomic, financial, and speculation variables over different sample periods. Results indicate that the dynamic equity-commodity correlations for the energy, grains and oilseeds, precious metals, and to a lesser extent the foods and fibers, sub-sectors have become increasingly explainable by broad macroeconomic and financial market indicators, particularly after May 2003. Furthermore, these variables exhibit heterogeneous effects in terms of both magnitude and sign on each sub-sectors' equity-commodity correlation structure. Interestingly, the effects of increased financial market speculation are found to be extremely varied among the five sub-sectors. These results have important implications for portfolio selection, price formation, and risk management. Chapter 2, entitled, "US Community Bank Failure: An Empirical Investigation," examines the declining, but still pivotal role, of the US community banking industry. The study utilizes survival analysis to determine which accounting and macroeconomic variables help to predict community bank failure. Federal Deposit Insurance Corporation and Federal Reserve Bank data are utilized to compare 452 community banks which failed between

  19. Empirical essays on energy economics

    Energy Technology Data Exchange (ETDEWEB)

    Thoenes, Stefan

    2013-06-13

    The main part of this thesis consists of three distinct essays that empirically analyze economic issues related to energy markets in the United States and Europe. The first chapter provides an introduction and discusses the motivation for the different analyses pursued in this thesis. The second chapter examines attention effects in the market for hybrid vehicles. We show that local media coverage, gasoline price changes and unprecedented record gasoline prices have a significant impact on the consumers' attention. As attention is not directly observable, we analyze online search behavior as a proxy for the revealed consumer attention. Our study is based on a unique weekly panel dataset for 19 metropolitan areas in the US. Additionally, we use monthly state-level panel data to show that the adoption rate of hybrid vehicles is robustly related to our measure of attention. Our results show that the consumers' attention fluctuates strongly and systematically. The third chapter shows how the effect of fuel prices varies with the level of electricity demand. It analyzes the relationship between daily prices of electricity, natural gas and carbon emission allowances with a semiparametric varying smooth coefficient cointegration model. This model is used to analyze the market impact of the nuclear moratorium by the German Government in March 2011. Futures prices of electricity, natural gas and emission allowances are used to show that the market efficiently accounts for the suspended capacity and correctly expects that several nuclear plants will not be switched on after the moratorium. In the fourth chapter, we develop a structural vector autoregressive model (VAR) for the German natural gas market. In particular, we illustrate the usefulness of our approach by disentangling the effects of different fundamental influences during four specific events: The financial crisis starting in 2008, the Russian-Ukrainian gas dispute in January 2009, the Libyan civil war

  20. Empirical essays on energy economics

    International Nuclear Information System (INIS)

    Thoenes, Stefan

    2013-01-01

    The main part of this thesis consists of three distinct essays that empirically analyze economic issues related to energy markets in the United States and Europe. The first chapter provides an introduction and discusses the motivation for the different analyses pursued in this thesis. The second chapter examines attention effects in the market for hybrid vehicles. We show that local media coverage, gasoline price changes and unprecedented record gasoline prices have a significant impact on the consumers' attention. As attention is not directly observable, we analyze online search behavior as a proxy for the revealed consumer attention. Our study is based on a unique weekly panel dataset for 19 metropolitan areas in the US. Additionally, we use monthly state-level panel data to show that the adoption rate of hybrid vehicles is robustly related to our measure of attention. Our results show that the consumers' attention fluctuates strongly and systematically. The third chapter shows how the effect of fuel prices varies with the level of electricity demand. It analyzes the relationship between daily prices of electricity, natural gas and carbon emission allowances with a semiparametric varying smooth coefficient cointegration model. This model is used to analyze the market impact of the nuclear moratorium by the German Government in March 2011. Futures prices of electricity, natural gas and emission allowances are used to show that the market efficiently accounts for the suspended capacity and correctly expects that several nuclear plants will not be switched on after the moratorium. In the fourth chapter, we develop a structural vector autoregressive model (VAR) for the German natural gas market. In particular, we illustrate the usefulness of our approach by disentangling the effects of different fundamental influences during four specific events: The financial crisis starting in 2008, the Russian-Ukrainian gas dispute in January 2009, the Libyan civil war in 2011 as

  1. Essays on incomplete contracts in regulatory activities

    Science.gov (United States)

    Saavedra, Eduardo Humberto

    This dissertation consists of three essays. The first essay, The Hold-Up Problem in Public Infrastructure Franchising, characterizes the equilibria of the investment decisions in public infrastructure franchising under incomplete contracting and ex-post renegotiation. The parties (government and a firm) are unable to credibly commit to the contracted investment plan, so that a second step investment is renegotiated by the parties at the revision stage. As expected, the possibility of renegotiation affects initial non-verifiable investments. The main conclusion of this essay is that not only underinvestment but also overinvestment in infrastructure may arise in equilibrium, compared to the complete contracting case. The second essay, Alternative Institutional Arrangements in Network Utilities: An Incomplete Contracting Approach, presents a theoretical assessment of the efficiency implications of privatizing natural monopolies which are vertically related to potential competitive firms. Based on the incomplete contracts and asymmetric information paradigm. I develop a model that analyzes the relative advantages of different institutional arrangements---alternative ownership and market structures in the industry--- in terms of their allocative and productive efficiencies. The main policy conclusion of this essay is that both ownership and the existence of conglomerates in network industries matter. Among other conclusions, this essay provides an economic rationale for a mixed economy in which the network is public and vertical separation of the industry when the natural monopoly is under private ownership. The last essay, Opportunistic Behavior and Legal Disputes in the Chilean Electricity Sector, analyzes post-contractual disputes in this newly privatized industry. It discusses the presumption that opportunistic behavior and disputes arise due to inadequate market design, ambiguous regulation, and institutional weaknesses. This chapter also assesses the presumption

  2. Axenfeld-Rieger anomaly and corneal endothelial dystrophy: a case series Anomalia de Axenfeld-Rieger e distrofia corneana endotelial: uma série de casos

    Directory of Open Access Journals (Sweden)

    Mariana Borges Oliveira

    2008-12-01

    Full Text Available Report of a study of a family with a remarkable combination of endothelial corneal dystrophy, and anterior chamber dysgenesis classified as Axenfeld-Rieger anomaly. A 56 year-old female had blurred vision complaints. A slit lamp evaluation showed a bilateral posterior embryotoxon and guttata with corneal edema, Descemet membrane's folds, characterizing Fuchs endothelial dystrophy. A 27 year-old daughter was asymptomatic. The biomicroscopic exam disclosed a bilateral nasal and temporal posterior embryotoxon and a central guttata. Gonioscopy showed iridocorneal strands with a prominent Schwalbe´s line. The intraocular pressure was normal. Her sister, a 25 year-old female presented very similar abnormalities along with her brother (22 years old. A 19 year-old female sister presented the iridocorneal angle alterations, without Fuchs endothelial dystrophy, until this moment. This paper presents a family with a central cornea guttata or Fuchs dystrophy associated with Axenfeld-Rieger anomaly. Two different inherited diseases appearing together in an entire family may suggest a single molecular and genetic etiology, with high penetrance.Relato dos resultados do estudo de uma família com distrofia corneana endotelial associada a uma disgenesia do segmento anterior, a anomalia de Axenfeld-Rieger. Paciente de 56 anos, feminina, queixava-se de visão borrada. O exame na lâmpada de fenda evidenciou embriotoxo posterior bilateral e guttata no centro da córnea, edema estromal e dobras na membrana de Descemet, caracterizando distrofia endothelial de Fuchs. A filha de 27 anos estava assintomática. A biomicroscopia revelou embriotoxo posterior nasal e temporal bilateral e guttata central. A gonioscopia evidenciou processos iridocorneanos até a linha de Schwalbe, que se encontrava anteriorizada e proeminente. A pressão intra-ocular estava normal. Não foram observadas alterações sistêmicas. Sua irmã, 25 anos, sexo feminino, apresentava altera

  3. ANÁLISE DE PADRÕES E DE ANOMALIAS DE DRENAGEM DA PORÇÃO MÉDIA DA BACIA DO RIO TIBAGI (PR

    Directory of Open Access Journals (Sweden)

    Idjarrury Gomes Firmino

    2017-03-01

    Full Text Available A porção média da bacia do rio Tibagi está localizada entre os municípios de Tibagi (PR e Telêmaco Borba (PR. A região compreende a borda planáltica da Bacia Sedimentar do Paraná e é o local por onde se projeta parte do eixo do Arco de Ponta Grossa. O objetivo principal desta pesquisa é a análise dos tipos de padrões e a identificação de anomalias de drenagem e de seus significados. A análise da rede de drenagem desta área permitiu identificar um predomínio de 68% do padrão treliça e subtipos, o que sugere que os rios possuem um forte controle estrutural por parte das falhas da Zona de Falha Curitiba-Maringá, alinhadas no sentido NW-SE e um sistema secundário de falhas e juntas no sentido NE-SW. A baixa sinuosidade para rios de primeira e segunda ordem, a angularidade média da rede de canais (maioria 90º, o predomínio de lineações e a tropia bidirecional também são fortes indicativos deste tipo de controle. A densidade de drenagem maior para as vertentes dos canais principais sugere um aprofundamento das vertentes em um processo de ascensão. As anomalias de drenagem identificadas (inflexões, alinhamentos, curvas fluviais comprimidas, planícies e terraços assimétricos estão relacionadas ao cruzamento de segmentos retilíneos e aos diques de diabásio. A análise da rede e de suas propriedades também permitiu setorizar áreas com controles distintos, como no reverso da escarpa, onde predomina o controle da atitude das camadas da Formação Furnas e da reentrância do Arco de Ponta Grossa.

  4. A técnica do cone para correção da anomalia de Ebstein: resultados imediatos e em longo prazo

    Directory of Open Access Journals (Sweden)

    José Pedro da Silva

    2011-09-01

    Full Text Available FUNDAMENTO: As principais correções da anomalia de Ebstein (AE baseiam-se na reconstrução monocúspide da valva tricúspide e são limitadas pela frequente necessidade de substituição ou pela alta reincidência de insuficiência valvar. OBJETIVO: Avaliar a viabilidade e os efeitos da correção anatômica da anomalia de Ebstein com a técnica do cone na evolução clínica dos pacientes, na função da valva tricúspide e na morfologia do ventrículo direito. MÉTODOS: Foram comparados os dados clínicos, ecocardiográficos e radiológicos de 52 pacientes consecutivos, com idade média de 18,5 ± 13,8anos, submetidos à técnica do cone, obtidos nos períodos pré-operatório, pós-operatório imediato (POI e em longo prazo (POL. RESULTADOS: Houve dois óbitos hospitalares (3,8% e mais dois durante o seguimento. A classe funcional média de insuficiência cardíaca pré-operatória de 2,2 melhorou para 1,2 após 57 meses de seguimento médio de 97% dos pacientes (p 0,05. A área funcional indexada do VD aumentou de 8,53 ± 7,02 cm2/m2 no préoperatório para 21,01±6,87 cm2/m2 no POI (p 0,05. O índice cardiotorácico médio foi reduzido de 0,66 ± 0,09 para 0,54 ± 0,06 (p < 0,001 em longo prazo. CONCLUSÃO: A técnica do cone apresentou baixa mortalidade hospitalar, corrigindo a insuficiência tricúspide de maneira eficaz e duradoura, com a restauração da área funcional do ventrículo direito, permitindo o remodelamento reverso do coração e a melhora clínica na maioria dos pacientes em longo prazo.

  5. Essays on Empirical Asset Pricing : Essays over het empirisch prijzen van financiele producten

    NARCIS (Netherlands)

    R.W.M. Verbeek (Roy)

    2017-01-01

    textabstractThis dissertation consists of three essays on empirical asset pricing. In the first essay, I investigate whether common risk factors are priced across investment horizons. I show that only the market and size factors are priced, but only up to sixteen months. The results highlight the

  6. Low estriol levels in the maternal marker screen as a predictor of X-linked adrenal hypoplasia congenita: Case report

    Directory of Open Access Journals (Sweden)

    Durković Jasmina

    2014-01-01

    Full Text Available Introduction. X-linked adrenal hypoplasia congenita (AHC is a rare cause of adrenocortical insufficiency. Early postnatal diagnosis may prevent severe hypoglycemia, Addisonian crises and death. Low maternal estriol (E3 levels in the second trimester of pregnancy could indicate the possibility that the fetus suffers from a disorder that causes adrenal insufficiency. Suspicion is based on the fact that E3 originates from dehydroepiandrosterone (DHEA synthesized in the fetal adrenals. In case of adrenal insufficiency, the impaired production of fetal DHEA leads to a subsequent reduction of E3 concentrations in maternal serum. There are only a few reports of AHC suspected prenatally due to low maternal E3 levels. Case Outline. We describe two brothers with adrenal insufficiency due to AHC. The older brother was admitted to the hospital at the age of 33 days due to failure to thrive, vomiting, and dehydration. Genetic analysis revealed a hemizygous mutation in DAX-1 gene, thus confirming the diagnosis of ACH. The same mutation was detected in his mother. In the second pregnancy, E3 concentrations were determined from maternal serum. Estriol levels during the second trimester were extremely low suggesting the diagnosis of AHC. The diagnosis was confirmed during the neonatal period by genetic testing, and replacement therapy was started at the age of 10 days. This boy never experienced an adverse episode such as hypoglycemia or adrenal crises. Conclusion. Since determination of E3 is a simple, sensitive, noninvasive and cheap method, its use as an obligatory prenatal screening test should be accepted as a standard practice in Serbia.

  7. Complex phenotype of dyskeratosis congenita and mood dysregulation with novel homozygous RTEL1 and TPH1 variants.

    Science.gov (United States)

    Ungar, Rachel A; Giri, Neelam; Pao, Maryland; Khincha, Payal P; Zhou, Weiyin; Alter, Blanche P; Savage, Sharon A

    2018-06-01

    Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome caused by germline mutations in telomere biology genes. Patients have extremely short telomeres for their age and a complex phenotype including oral leukoplakia, abnormal skin pigmentation, and dysplastic nails in addition to bone marrow failure, pulmonary fibrosis, stenosis of the esophagus, lacrimal ducts and urethra, developmental anomalies, and high risk of cancer. We evaluated a patient with features of DC, mood dysregulation, diabetes, and lack of pubertal development. Family history was not available but genome-wide genotyping was consistent with consanguinity. Whole exome sequencing identified 82 variants of interest in 80 genes based on the following criteria: homozygous, <0.1% minor allele frequency in public and in-house databases, nonsynonymous, and predicted deleterious by multiple in silico prediction programs. Six genes were identified likely contributory to the clinical presentation. The cause of DC is likely due to homozygous splice site variants in regulator of telomere elongation helicase 1, a known DC and telomere biology gene. A homozygous, missense variant in tryptophan hydroxylase 1 may be clinically important as this gene encodes the rate limiting step in serotonin biosynthesis, a biologic pathway connected with mood disorders. Four additional genes (SCN4A, LRP4, GDAP1L1, and SPTBN5) had rare, missense homozygous variants that we speculate may contribute to portions of the clinical phenotype. This case illustrates the value of conducting detailed clinical and genomic evaluations on rare patients in order to identify new areas of research into the functional consequences of rare variants and their contribution to human disease. © 2018 Wiley Periodicals, Inc.

  8. Three essays in energy and environmental economics

    Science.gov (United States)

    Redlinger, Michael

    This thesis exploits the boom in U.S. oil and gas production to explore several empirical questions in environmental and energy economics. In the first essay, statistical techniques are employed to evaluate learning-by-doing in the Bakken Shale Play. Furthermore, the essay demonstrates organizational forgetting and knowledge spillovers among firms. The results show rates of learning in an important sector the U.S. economy and may have broader lessons for productivity gains and losses. The second essay investigates interfirm learning economies in oil well drilling in terms of productivity improvements and increases in environmental safety. The empirical results improve our understanding of how interfirm relationships influence productivity as well as the drivers of environmental incidents. Lastly, the third essay analyzes the impacts of stricter environmental regulations on oil production and well drilling in North Dakota. The results have particular relevance for policymakers seeking to understand the trade-offs between resource development and environmental quality. These three essays ultimately expand our knowledge of how learning economies occur and the effects of environmental regulations on economic activity.

  9. Essays on Macroeconomics and Oil

    Science.gov (United States)

    Cakir, Nida

    In these essays, I examine (i) the empirical methods that are widely used in the literature to measure total factor productivity growth and (ii) the impact of nationalization on productivity in the oil industry. The first chapter, which is an ongoing work with SHI, Wei, investigates two empirical measures, quantity-based (primal) measure and price-based (dual) measure, of total factor productivity growth. My co-author and I analyze how these two measures are affected by output market imperfection or variable capacity utilization. We find that under constant-returns-to-scale production function assumption, existence of the imperfect competition in the output market creates a gap between the measured TFP growth and the true TFP growth, no matter which method is used. However, theoretically, it does not affect the equivalence between the two measures. Under variable capacity utilization, we show that constant-returns-to-scale assumption is almost enough to guarantee the validity of the two methods in correctly capturing the true TFP growth. In the second and third chapters, I analyze the link between nationalization and productivity. The second chapter documents the trends in expropriation acts, and evaluates the impact of expropriations on labor productivity of resource-rich developing countries in the oil industry. In the first part of this chapter, I investigate the trends in the expropriation acts that took place in 102 developing countries during the period 1922-2006. I find that more than half of the acts occurred between 1970 and 1976, there has been an increase in the number of expropriations in recent years, and the extractive sector including petroleum is more likely to be expropriated. Motivated by these facts, in the second part, I examine the oil industry in a period of widespread expropriations, the 1970s. In a sample of major oil-producing countries including OPEC and non-OPEC members, I show that losses in relative labor productivity after

  10. Blue Marble Space Institute essay contest

    Science.gov (United States)

    Wendel, JoAnna

    2014-04-01

    The Blue Marble Space Institute of Science, based in Seattle, Wash., is inviting college students to participate in its essay contest. Essays need to address the question, "In the next 100 years, how can human civilization prepare for the long-term changes to the Earth system that will occur over the coming millennium?" According to the institute, the purpose of the contest is "to stimulate creative thinking relating to space exploration and global issues by exploring how changes in the Earth system will affect humanity's future."

  11. The Early (Feminist) Essays of Victoria Ocampo

    OpenAIRE

    Doris Meyer

    1996-01-01

    This study examines the essays written by Ocampo between 1920 and 1934, prior to the time when she publicly voiced her adhesion to feminism and the rights of women in Argentine society. In these works from her Testimonios in which Ocampo struggles to find her voice as a female writer, the maleable essay serves her need to engage in discursive dialogues from the margins of the literary culture of her time. Both as a woman and a member of the oligarchy, she questions cultural assumptions and ...

  12. Essays in empirical finance and monetary policy

    NARCIS (Netherlands)

    van Holle, Frederiek

    2017-01-01

    This dissertation consists of three essays. In the first paper, “Stock-Bond Correlations, Macroeconomic Regimes and Monetary Policy”, we link the evolution of stock-bond correlations for an international sample to both local and global regimes in inflation, the output gap and monetary policy. We

  13. French Higher Education: A Cartoon Essay

    Science.gov (United States)

    Hall, Matthew Henry

    2012-01-01

    In this cartoon essay, the author shares his experience from a travel to Paris to see the French higher education system. From his travel, he learned that in France, "degree" inflation may be an issue, but not grade inflation. On the flight home, the author reflects how French and American academics answer one question about the state of…

  14. Can Style Be Creative? An Exploratory Essay

    Science.gov (United States)

    Clinton, Gregory

    2016-01-01

    This essay explores the nature of creativity of the practicing professional through the examination of the role of personal style in creative work, as well as how personality can affect and sustain creativity. Instructional designers, as practicing creatives, must balance the divergent and novel with the restraints of clients, projects, and…

  15. A Small Essay About a Big Boulevard

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2015-08-01

    Full Text Available The essay presents the analogies of turning city borders and walls into boulevards and gardens through the examples of Moscow and Irkutsk. The main street of Irkutsk is viewed in a new light, as a boulevard. It is proposed to take into consideration the peculiarities of the four sense-parts of the street when working on design codes.

  16. Aristotle, De Memoria et Reminiscentia. Text, Translation and Interpretive Essays

    DEFF Research Database (Denmark)

    Bloch, David Kristian

    2006-01-01

    The dissertation analyses Aristotle's De Memoria et Reminiscentia. It contains an introduction, a critical edition accompanied by an English translation, an essay on Aristotle's own theories and an essay on the Aristotelian tradition.......The dissertation analyses Aristotle's De Memoria et Reminiscentia. It contains an introduction, a critical edition accompanied by an English translation, an essay on Aristotle's own theories and an essay on the Aristotelian tradition....

  17. Essaying the essay: nursing scholarship and the hegemony of the laboratory.

    Science.gov (United States)

    Gardner, Lyn; Rolfe, Gary

    2013-01-01

    It might appear odd or even perverse to be arguing for the essay as a vehicle for academic thought and writing, particularly given the current emphasis on scientific research and evidence-based practice. In fact, the scholarly essay has virtually ceased to exist as an academic form in practice disciplines such as nursing, excluded by what we will identify and refer to as the hegemony of the laboratory. In a practical as well as an intellectual attempt to reinstate it, this paper is structured in the form of two consecutive short essays. In the first, we identify the character, features and purpose of the scholarly essay and examine its demise as an academic form. In the second, we explore some possible reasons why the essay never became fully accepted as an academic form in nursing. We suggest that the essay is thematically eclectic and stylistically promiscuous, drawing from a broad range of cultural, disciplinary and academic reference points. As such, it presents a challenge to the dominant technical rational approach to academic nursing in both its form and its content, particularly in its disregard for the rigidly imposed genres and structures increasingly demanded by academic nursing journals. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Conceptualizing Essay Tests' Reliability and Validity: From Research to Theory

    Science.gov (United States)

    Badjadi, Nour El Imane

    2013-01-01

    The current paper on writing assessment surveys the literature on the reliability and validity of essay tests. The paper aims to examine the two concepts in relationship with essay testing as well as to provide a snapshot of the current understandings of the reliability and validity of essay tests as drawn in recent research studies. Bearing in…

  19. Intertextual Trips: Teaching the Essay in the Composition Class.

    Science.gov (United States)

    Kline, Nancy

    1989-01-01

    Cites essays by Joan Didion, John Berryman, and Martin Luther King in arguing that the essay, no matter how serious, can be considered as a fiction and a playful, exploratory and deeply interesting rhetorical game. Describes how these works were used to teach students that the essay is a living document calling for interaction. (SG)

  20. Essays on Social Media Fundraising and E-Commerce

    Science.gov (United States)

    Tan, Xue

    2017-01-01

    This dissertation has two components: social media fundraising and e-commerce. The first component of social media fundraising discusses social media users' charitable content generation in essay 1 and charitable giving in essay 2. In essay 1, we examine how reciprocity of followees affects social influence on users' charitable content generation.…

  1. Giving Personal Examples and Telling Stories in Academic Essays.

    Science.gov (United States)

    Hinkel, Eli

    2001-01-01

    Analyzes the extensive use of personal examples and stories in the academic essays of students who are nonnative speakers of English. Draws on a large database of college examination essays to compare the use of personal examples in essays written by native and nonnative speakers. Finds nonnative students not only use examples more often than…

  2. Tricuspid valve dysplasia and Ebstein's anomaly in dogs: case report Displasia da valva tricúspide e anomalia de Ebstein em cães: relato de caso

    Directory of Open Access Journals (Sweden)

    M.G. Sousa

    2006-10-01

    Full Text Available Two cases of tricuspid valve dysplasia are reported. Dogs were presented for evaluation of weakness and ascites. In both cases, echocardiography disclosed tricuspid insufficiency and, in one of them, tricuspid leaflets also were displaced down into the right ventricle, substantiating Ebstein's anomaly. Medical therapy for congestive heart failure was initiated. One of the dogs suddenly died shortly after diagnosis was established. Although the other dog recovered much better initially, sudden death also occurred. Post-mortem examinations showed right atrioventricular enlargement, and thickened tricuspid leaflets. Clinical features, diagnostic methods and medical therapy are discussed in this paper.Dois casos de displasia da valva tricúspide são relatados neste trabalho. Os cães foram avaliados devido à fraqueza e presença de ascite. Em ambos os casos, o exame ecocardiográfico mostrou insuficiência tricúspide e, em um deles, a inserção dos folhetos da valva tricúspide encontrava-se deslocada para baixo do ventrículo direito, caracterizando a anomalia de Ebstein. A terapia medicamentosa para insuficiência cardíaca congestiva foi iniciada, mas um dos animais veio a óbito subitamente alguns dias após o diagnóstico. O outro cão, apesar de inicialmente ter apresentado melhora significativa do quadro clínico, apresentou morte súbita. A necropsia dos animais revelou dilatação atrioventricular direita e folhetos tricúspides espessados. As características clínicas, métodos de diagnóstico e terapia medicamentosa são discutidas neste artigo.

  3. Análise do regime hídrico de Patos-PB por meio do Índice de Anomalia de Chuvas (IAC

    Directory of Open Access Journals (Sweden)

    M. F. A. Alves

    2015-12-01

    Full Text Available A seca é um fenômeno natural que o ser humano não consegue impedir que ocorra. Nesse sentido, a presente pesquisa tem por objetivo, analisar o comportamento do regime hídrico do município de Patos interior da Paraíba, no período de 1994 a 2009 utilizando o IAC. Para o desenvolvimento da pesquisa, realizou-se um levantamento pluviométrico de 15 anos obtidos no site da Agência Executiva de Gestão das Águas da Paraíba (AESA de 1994 a 2009. Os dados foram disponibilizados em planilha eletrônica do Microsoft Excel com informações diárias, mensais e anuais e por último foi analisado o comportamento das precipitações através do Índice de Anomalia de Chuva (IAC, que é bastante simples e empregado para avaliação dos períodos secos ou úmidos. Pelo o estudo observou-se que apenas 2009 apresentou um mês (abril, como extremamente úmido e os demais anos foram classificados como muito úmidos, úmidos e secos. O ano mais seco foi 1998 que apresentou anomalias negativas de fevereiro a maio, seguido de 1999 com anomalias negativas em fevereiro e abril do período chuvoso. Dos resultados se percebe que as principais chuvas que ocorrem sob a região estudada caem sobre a terra de forma mal distribuída e irregular, e que o índice pluviométrico da região, se comparado com outras regiões áridas do planeta, o semiárido paraibano é um dos que mais chove em todo mundo, deixando claro que a falta de água que assola os nordestinos são decorrentes das características das chuvas. Percebe-se que apenas 2009 apresentou mês tido como extremamente úmido e isso não é caraterístico da região, devendo-se, sobretudo a modelos de estabilização da atmosfera por eventos meteorológicos que provocaram as chuvas fora do período chuvoso de Patos. Analysis of water regime of Patos-PB through Rainfall Anomaly Index (RAIAbstract: Drought is a natural phenomenon that humans can't prevent that from occurring. In this sense, this research aims

  4. Anomalia de Ebstein detectada in utero e síndrome de Down: diagnóstico pré-natal de uma combinação rara Intrauterine detection of Ebstein's anomaly and Down's syndrome: prenatal diagnosis of a rare combination

    Directory of Open Access Journals (Sweden)

    Maria de Fátima M.P. Leite

    2004-04-01

    Full Text Available A anomalia de Ebstein é uma doença rara, embora seja a malformação mais comum da valva tricúspide. A associação com outras síndromes e anomalias extracardíacas é muito incomum e matéria de poucos relatos de caso. Apresenta-se um caso de diagnóstico pré-natal de anomalia de Ebstein em um paciente com síndrome de Down.Ebstein's anomaly, although the most common malformation of the tricuspid valve, is a rare disease. Its association with other syndromes and extracardiac anomalies is very rare and has been reported in only a few cases. A case of prenatal diagnosis of Ebstein's anomaly in a patient with Down's syndrome is reported.

  5. Essays on Asset Pricing with Financial Frictions

    DEFF Research Database (Denmark)

    Klingler, Sven

    The first essay focuses on Credit default swap (CDS) premiums of safe sovereigns, that is, the insurance against the default of countries with a low credit risk, like Germany, Japan, or the United States. We motivate the essay by establishing the following two stylized facts. First, we document...... insurance against the default of safe sovereigns? Second, what drives safe-haven CDS premiums if not credit risk?...... between bond yield and risk-free rate, for safe sovereigns. This finding is in opposition to the no-arbitrage theory that CDS premiums and yield spreads should move in lockstep. Motivated by these stylized facts, we investigate the following two questions: First, what are the motives behind purchasing...

  6. Essays in renewable energy and emissions trading

    Science.gov (United States)

    Kneifel, Joshua D.

    Environmental issues have become a key political issue over the past forty years and has resulted in the enactment of many different environmental policies. The three essays in this dissertation add to the literature of renewable energy policies and sulfur dioxide emissions trading. The first essay ascertains which state policies are accelerating deployment of non-hydropower renewable electricity generation capacity into a states electric power industry. As would be expected, policies that lead to significant increases in actual renewable capacity in that state either set a Renewables Portfolio Standard with a certain level of required renewable capacity or use Clean Energy Funds to directly fund utility-scale renewable capacity construction. A surprising result is that Required Green Power Options, a policy that merely requires all utilities in a state to offer the option for consumers to purchase renewable energy at a premium rate, has a sizable impact on non-hydro renewable capacity in that state. The second essay studies the theoretical impacts fuel contract constraints have on an electricity generating unit's compliance costs of meeting the emissions compliance restrictions set by Phase I of the Title IV SO2 Emissions Trading Program. Fuel contract constraints restrict a utility's degrees of freedom in coal purchasing options, which can lead to the use of a more expensive compliance option and higher compliance costs. The third essay analytically and empirically shows how fuel contract constraints impact the emissions allowance market and total electric power industry compliance costs. This paper uses generating unit-level simulations to replicate results from previous studies and show that fuel contracts appear to explain a large portion (65%) of the previously unexplained compliance cost simulations. Also, my study considers a more appropriate plant-level decisions for compliance choices by analytically analyzing the plant level decision-making process to

  7. På kant med Kant : Et bekjennende essay

    OpenAIRE

    Dahl, Per

    2013-01-01

    Kant can’t always be right. There are some aspects of Kant’s philosophy that make him unsuitable for the understanding of a musical experience. His contribution to aesthetic theory is developed in the Critique of Judgement (1790), where he investigates the possibility and logical status of “judgements of taste”. In this essay, I argue that his exploration of the inherent limits of our knowledge through philosophical reasoning seems to impede an understanding of the musical expe...

  8. Essays on investor behavior and trading activity

    OpenAIRE

    Kyröläinen, P. (Petri)

    2007-01-01

    Abstract This thesis investigates a set of equity market phenomena associated with investors' trading activity, using a comprehensive Finnish Central Securities Depository (FCSD) database that records practically all trades by Finnish investors. This database enables us to classify a large number of heterogeneous investors using both economic and institutional characteristics. The first essay classifies investors by trading activity. It analyzes trading styles of active and passive inv...

  9. Three essays in control, entrepreneurship and innovation

    OpenAIRE

    Cardenas, F.

    2012-01-01

    One of the key emphases of these three essays is to provide practical managerial insight. However, good practical insight, can only be created by grounding it firmly on theoretical and empirical research. Practical experience-based understanding without theoretical grounding remains tacit and cannot be easily disseminated. Theoretical understanding without links to real life remains sterile. My studies aim to increase the understanding of how radical innovation could be generated at large est...

  10. Essays on Learning, Uncertainty, and Choice

    OpenAIRE

    Frick, Mira Anna Phyllis

    2015-01-01

    This dissertation presents three independent essays in microeconomic theory. Motivated by the rise of social media, Chapter 1 (co-authored with Yuhta Ishii) builds a model studying the effect of an economy's potential for social learning on the adoption of innovations of uncertain quality. Provided consumers are forward-looking (i.e. recognize the value of waiting for information), equilibrium dynamics depend non-trivially on qualitative and quantitative features of the informational envir...

  11. Essays on environmental policies, corruption, and energy

    Science.gov (United States)

    Baksi, Soham

    This thesis consists of four essays. The first essay looks at pollution taxation under capital mobility, and analyzes the role of pre-commitment by countries to their pollution tax rate. A polluting firm sells its product in two countries, and can locate and produce in a single country or in both countries. Due to the discrete-choice nature of the firm's location problem, the countries' welfare functions are discontinuous in their pollution tax rate. We show that when the countries cannot pre-commit to their pollution tax, the firm can still engender tax competition between them by strategically locating in both the countries. Moreover, pre-commitment pollution taxation may not be welfare improving for the countries, although it always makes the firm better off. The second essay studies the effect of liberalization on corruption. Corruptible inspectors enforce an environmental regulation on firms, and are monitored by an honest regulator. Liberalization not only increases the variety of goods and the marginal utility of accepting a bribe, but also puts pressure on the regulator to curb corruption. The interaction of these two effects can cause corruption to initially increase with liberalization, and then decrease beyond a threshold. Moreover, equilibrium corruption is lower when the regulator is able to pre-commit to her monitoring frequency. The third essay analyzes optimal labeling (information revelation) procedures for hidden attributes of credence goods. Consumers are heterogeneous in their preference for the hidden attribute, and producers can either self-label their products, or have them certified by a third party. The government can impose self or third-party labeling requirements on either the "green" or the "brown" producers. When corrupt producers can affix spurious labels, the government needs to monitor them. A mandatory self-labeling policy is shown to generally dominate mandatory third-party labeling. The fourth essay develops formulas for

  12. Anomalias craniofaciais: descrição e avaliação das características gerais da atenção no Sistema Único de Saúde

    Directory of Open Access Journals (Sweden)

    Isabella Lopes Monlleó

    2006-05-01

    Full Text Available A primeira iniciativa para incluir a atenção às anomalias craniofaciais no SUS ocorreu em 1993. Um importante avanço foi a criação da Rede de Referência no Tratamento de Deformidades Craniofaciais (RRTDCF, atualmente com 29 centros credenciados. Os objetivos deste estudo foram descrever e avaliar as características gerais da atenção às anomalias craniofaciais nos centros que integram a referida rede. Foi utilizado questionário semi-estruturado, remetido por correio. Obteve-se 86,2% de respostas. Os resultados demonstram agregação de centros no Sudeste, em universidades e na área de fissuras labiopalatais; financiamento predominantemente público; equipes constituídas principalmente de acordo com parâmetros norte-americanos; atendimento de rotina em cerca de 90% e utilização de protocolos em cerca de 70% dos centros. A denominação da RRTDCF não parece corresponder à sua abrangência. Os achados sugerem necessidade de revisão da definição, objetivos e abrangência da RRTDCF e dos critérios de credenciamento de centros.

  13. Síndrome de Rubinstein-Taybi: anomalias físicas, manifestações clínicas e avaliação auditiva

    Directory of Open Access Journals (Sweden)

    Martins Regina H. G.

    2003-01-01

    Full Text Available INTRODUÇÃO: A Síndrome de Rubinstein-Taybi foi descrita pela primeira vez em 1963, após a observação dos traços físicos semelhantes apresentados por sete crianças com retardo mental, baixa estatura, polegares grandes e largos e anomalias faciais. Mais tarde, novas publicações definiram outras características dessa síndrome, a qual incide em 1 a cada 300.000 nascidos e apresenta etiologia incerta. Sintomas otorrinolaringológicos e fonoaudiológicos são freqüentes, daí a importância de melhor conhecimento dessa síndrome por esses especialistas. RELATO DE CASO: Apresentamos as principais manifestações clínicas, traços físicos e as avaliações auditivas de cinco crianças portadoras da Síndrome de Rubinstein-Taybi, em atendimento na Faculdade de Medicina de Botucatu (UNESP. Para as avaliações auditivas foram realizados exames de audiometria tonal, imitanciometria e potenciais evocados do tronco encefálico (BERA. As principais características observadas foram: retardo mental, baixa estatura, polegares largos, pirâmide nasal alta, palato ogival, má oclusão dentária, atraso no desenvolvimento neuropsicomotor e de linguagem. DISCUSSÃO: Os traços físicos característicos dos portadores dessa síndrome facilitam o diagnóstico, e muitos deles são responsáveis por sintomas otorrinolaringológicos e fonoaudiológicos, como infeções de vias aéreas superiores, obstrução nasal, otites médias, hipertrofia adenoamigdaliana, surdez condutiva, hipotonia perioral e disfagia. O importante comprometimento cognitivo é responsável pelo atraso no desenvolvimento da linguagem e pelo baixo rendimento escolar. CONCLUSÕES: Frente às várias manifestações otorrinolaringológicas e fonoaudiológicas apresentadas pelas crianças portadoras da Síndrome de Rubinstein-Taybi, torna-se necessário que esses especialistas conheçam melhor essa síndrome para que possam fazer o diagnóstico precoce e orientar o tratamento dessas

  14. Estudo da morbidade e da mortalidade perinatal em maternidades: III - Anomalias congênitas em nascidos vivos A study of perinatal morbidity and mortality in maternity hospitals: III - Congenital anomalies in live briths

    Directory of Open Access Journals (Sweden)

    José Maria Pacheco de Souza

    1987-02-01

    Full Text Available Realizou-se estudo das anomalias congênitas encontradas em recém-nascidos vivos, em nove maternidades, durante o ano de 1981-1982. O material é parte de uma pesquisa desenvolvida em sete maternidade do Estado de São Paulo, uma do Rio de Janeiro e uma de Florianópolis, Santa Catarina (Brasil, no período de agosto de 1981 a julho de 1982, quando foram coletados dados sobre todos os nascimentos ocorridos nesses nove serviços. As anomalias congênitas foram definidas como as descritas no XIV.° capítulo da Classificação Internacional de Doenças - 1975, 9ª Revisão, tendo sido utilizada essa classificação para codificá-las. Na análise estatística foram utilizados o X² (com um grau de liberdade, o teste de inclinação para proporções ("Trend test" e a técnica de Berkson para a verificação da hipótese de aderência à distribuição de Poisson. Em 12.782 recém-nascidos vivos, 286 (2,24% apresentavam algum tipo de anomalia congênita, tendo havido 26 (0,20% crianças com duas anomalias, 9 (0,07% com três e duas (0,02 apresentando quatro tipos de malformações congênitas. As deformidades osteomusculares congênitas (código 754 da CID foram as mais freqüentes (19%;segue-se as outras anomalias congênitas do coração (746 com uma freqüência de 14,1%. Ao se analisar a prevalência dessas malformações pela idade da mãe nota-se que há um aumento da prevalência à medida que a idade avança, apenas para Sindrome de Down (758.Congenital anomalies in live births in nine maternities in the period 1981-1982 were studied. This was one aspect of a research project carried out in seven maternities in the State of S.Paulo, one in Rio de Janeiro and another in Florianópolis (Brazil, from which data on all births occurring between August 1981 and July 1982 were obtained. Congenital anomalies were classified according to the XIVth chapter of the CID-1975 - 9thRevision. Chi square for associations and for trend and Berkson

  15. The theory of relativity and other essays

    CERN Document Server

    Einstein, Albert

    2011-01-01

    E=mc2: It may be Einstein's most well-known contribution to modern science, but how many people understand the thought process or physics behind this famous equation?In this collection of his seven most important essays on physics, Einstein guides his reader step-by-step through the many layers of scientific theory that formed a starting point for his discoveries. By both supporting and refuting the theories and scientific efforts of his predecessors, Einstein reveals in a clear voice the origins and meaning of such significant topics as physics and reality, the fundamentals of theoretical ph

  16. Essays on oil and the macroeconomy

    Energy Technology Data Exchange (ETDEWEB)

    Melolinna, M.

    2012-07-01

    This dissertation studies the effects of crude oil on the macroeconomy using a vector autoregression (VAR) modelling framework. In particular, the importance of identifying different types of oil shocks is explored for both small and large open economies. A VAR model is also used to study the information content of oil futures contracts. The dissertation consists of three essays. The first essay of the dissertation introduces a methodology for identifying oil supply shocks in a small open economy. Financial market information is used to construct an identification scheme that forces the response to an oil shock of the VAR model to be the same as that implied by futures markets. Due to the identification scheme, the model is only partially identified, and confidence intervals for impulse responses are calculated by using a bootstrapping procedure. The methodology is applied in illustrative examples to two small open economies in a VAR model that includes key domestic and international macroeconomic variables. The results suggest that while oil supply shocks have had an effect on domestic inflation during recent past, the effect on domestic GDP is ambiguous. The second essay of the dissertation studies the existence of risk premiums in crude oil futures prices with simple ordinary least squares regression and Bayesian VAR models. It also studies the importance of three main theoretical risk premium models in explaining and forecasting the risk premiums in practice. Whilst the existence of the premiums and the validity of the models can be established at certain time points, it turns out that the choice of sample period has a considerable effect on the results. Hence, the risk premiums are highly time-varying. The study also establishes a model, based on speculative positions in the futures markets, which has some predictive power for future oil spot prices. The third essay of the dissertation explores oil market and other macroeconomic shocks in a structural VAR

  17. Three essays on human resource management

    OpenAIRE

    Avgoustaki, Argyro

    2012-01-01

    This thesis comprises three essays on human resource management. The first one studies the effect of on-the-job training on firm productivity using a micro-dataset of a large firm in Greece for the period 2005 to 2006. The data consist of daily observations on the productivity of the same workers tracked before, during, and after the receipt of training. Overall, the empirical findings show that after the implementation of on-the-job training, productivity improves by almost 6.5 percent. Resu...

  18. Essays in real-time forecasting

    OpenAIRE

    Liebermann, Joelle

    2012-01-01

    This thesis contains three essays in the field of real-time econometrics, and more particularlyforecasting.The issue of using data as available in real-time to forecasters, policymakers or financialmarkets is an important one which has only recently been taken on board in the empiricalliterature. Data available and used in real-time are preliminary and differ from ex-postrevised data, and given that data revisions may be quite substantial, the use of latestavailable instead of real-time can s...

  19. Archives and societal provenance Australian essays

    CERN Document Server

    Piggott, Michael

    2012-01-01

    Records and archival arrangements in Australia are globally relevant because Australia's indigenous people represent the oldest living culture in the world, and because modern Australia is an ex-colonial society now heavily multicultural in outlook. Archives and Societal Provenance explores this distinctiveness using the theoretical concept of societal provenance as propounded by Canadian archival scholars led by Dr Tom Nesmith. The book's seventeen essays blend new writing and re-workings of earlier work, comprising the fi rst text to apply a societal provenance perspective to a national sett

  20. Cholestatic jaundice by malignant lesions: pictorial essay

    International Nuclear Information System (INIS)

    Santa Anna, Tatiana Kelly Brasileiro de; Santana, Alex Menezes; Rizzuto, Mauricio Soares; Chagas, Alessandro Rosa Rodrigues; Zuppani, Aguinaldo Cunha; Rezende, Marcelo Bruno; Viveiros, Marcelo de Melo

    2009-01-01

    Malignant obstructive jaundice is most commonly caused by cancer of pancreatic head, papilla tumor, cholangiocarcinoma and biliary obstruction induced by secondary lesions of the liver or lymph nodes. Patients usually present with weight loss, abdominal pain, jaundice and progressive increase of direct bilirubin, being essential the evaluation by imaging methods for the proper diagnosis, staging and therapeutic planning. This essay illustrates the imaging aspects of ultrasound and computed tomography - and in specific situations magnetic resonance cholangiography - of the major malignancies that lead to cholestatic jaundice. (author)

  1. Automated Essay Grading using Machine Learning Algorithm

    Science.gov (United States)

    Ramalingam, V. V.; Pandian, A.; Chetry, Prateek; Nigam, Himanshu

    2018-04-01

    Essays are paramount for of assessing the academic excellence along with linking the different ideas with the ability to recall but are notably time consuming when they are assessed manually. Manual grading takes significant amount of evaluator’s time and hence it is an expensive process. Automated grading if proven effective will not only reduce the time for assessment but comparing it with human scores will also make the score realistic. The project aims to develop an automated essay assessment system by use of machine learning techniques by classifying a corpus of textual entities into small number of discrete categories, corresponding to possible grades. Linear regression technique will be utilized for training the model along with making the use of various other classifications and clustering techniques. We intend to train classifiers on the training set, make it go through the downloaded dataset, and then measure performance our dataset by comparing the obtained values with the dataset values. We have implemented our model using java.

  2. Essays on regulation, institutions, and industrial organization

    Science.gov (United States)

    Bergara, Mario Esteban

    Essay I develops a comparative institutional analysis of network access price regulation and "light-handed" regulation. While the former is a specific-agency-based arrangement with higher political influence, the latter is a court-based system. Consequently, the main trade-off between both frameworks reflects the merits of having efficient political and judicial institutions. Price regulation is superior when distributional concerns are irrelevant and information asymmetries are lower. Poorly functioning political systems and high welfare costs of raising funds make price regulation less attractive. Light regulation is more attractive when potential rents are smaller, the monopolist is more risk averse, the judicial system is more efficient, and the threat of government intervention is more credible. The possibility of private transfers makes price regulation more advantageous. Higher information asymmetries among firms makes light-handed regulation more attractive. The main results are consistent with a plausible interpretation of the drastic deregulatory process in New Zealand. Essay II studies the preliminary effects of the deregulation of direct access in the New Zealand's electricity market. A slight improvement in quality standards and an overall efficiency increase took place after two years of deregulation. Retailers were able to successfully enter in large demand, dense areas, with a large proportion of industrial and commercial users, where incumbents were not distributing electricity efficiently. Pricing policies appears to be influenced by market forces (associated to economic and demographic characteristics) as expected in a light regulatory framework. Essay III focuses on the possibility of endogenous sunk costs and the introduction of new products. Firms that exert some monopoly power in one market and introduce a new good whose demand is determined by a broader set of consumers might be forced to change their competing strategies. If the new product

  3. Essays in energy economics: The electricity industry

    Science.gov (United States)

    Martinez-Chombo, Eduardo

    Electricity demand analysis using cointegration and error-correction models with time varying parameters: The Mexican case. In this essay we show how some flexibility can be allowed in modeling the parameters of the electricity demand function by employing the time varying coefficient (TVC) cointegrating model developed by Park and Hahn (1999). With the income elasticity of electricity demand modeled as a TVC, we perform tests to examine the adequacy of the proposed model against the cointegrating regression with fixed coefficients, as well as against the spuriousness of the regression with TVC. The results reject the specification of the model with fixed coefficients and favor the proposed model. We also show how some flexibility is gained in the specification of the error correction model based on the proposed TVC cointegrating model, by including more lags of the error correction term as predetermined variables. Finally, we present the results of some out-of-sample forecast comparison among competing models. Electricity demand and supply in Mexico. In this essay we present a simplified model of the Mexican electricity transmission network. We use the model to approximate the marginal cost of supplying electricity to consumers in different locations and at different times of the year. We examine how costs and system operations will be affected by proposed investments in generation and transmission capacity given a forecast of growth in regional electricity demands. Decomposing electricity prices with jumps. In this essay we propose a model that decomposes electricity prices into two independent stochastic processes: one that represents the "normal" pattern of electricity prices and the other that captures temporary shocks, or "jumps", with non-lasting effects in the market. Each contains specific mean reverting parameters to estimate. In order to identify such components we specify a state-space model with regime switching. Using Kim's (1994) filtering algorithm

  4. Essay on Option Pricing, Hedging and Calibration

    DEFF Research Database (Denmark)

    da Silva Ribeiro, André Manuel

    Quantitative finance is concerned about applying mathematics to financial markets.This thesis is a collection of essays that study different problems in this field: How efficient are option price approximations to calibrate a stochastic volatilitymodel? (Chapter 2) How different is the discretely...... of dynamics? (Chapter 5) How can we formulate a simple free-arbitrage model to price correlationswaps? (Chapter 6) A summary of the work presented in this thesis: Approximation Behooves Calibration In this paper we show that calibration based on an expansion approximation for option prices in the Heston...... stochastic volatility model gives stable, accurate, and fast results for S&P500-index option data over the period 2005 to 2009. Discretely Sampled Variance Options: A Stochastic Approximation Approach In this paper, we expand Drimus and Farkas (2012) framework to price variance options on discretely sampled...

  5. Review essay: empires, ancient and modern.

    Science.gov (United States)

    Hall, John A

    2011-09-01

    This essay drews attention to two books on empires by historians which deserve the attention of sociologists. Bang's model of the workings of the Roman economy powerfully demonstrates the tributary nature of per-industrial tributary empires. Darwin's analysis concentrates on modern overseas empires, wholly different in character as they involved the transportation of consumption items for the many rather than luxury goods for the few. Darwin is especially good at describing the conditions of existence of late nineteenth century empires, noting that their demise was caused most of all by the failure of balance of power politics in Europe. Concluding thoughts are offered about the USA. © London School of Economics and Political Science 2011.

  6. Essays in Education, Crime, and Job Displacement

    DEFF Research Database (Denmark)

    Bennett, Patrick

    , Crime, and Job Displacement”, analyzes the determinants and social implications of these three factors. While independent, each essay within this thesis examines the impact of factors such as education, in terms of reduced crime, job loss, in terms of increased crime, and discrimination, in terms of its......With a limited budget and resources, governments must decide how to allocate funds across a variety of factors which benefit society such as education, crime deterrence, and public safety. Each increase in spending on one area comes with the knowledge that this money cannot be spent on social...... problems in another area. As such, externalities and unexpected spillover effects impact the costs and benefits of public spending to society and may have large and meaningful implications on how to most effectively allocate resources across a multitude of outcomes. For example, an increase in education...

  7. Pictorial Essay: Infants of diabetic mothers

    International Nuclear Information System (INIS)

    Alorainy, Ibrahim A; Barlas, Nauman B; Al-Boukai, Amer A

    2010-01-01

    About 3 to 10% of pregnancies are complicated by glycemic control abnormalities. Maternal diabetes results in significantly greater risk for antenatal, perinatal, and neonatal morbidity and mortality, as well as congenital malformations. The number of diabetic mothers is expected to rise, as more and more of the obese pediatric female population in developed and some developing countries progresses to childbearing age. Radiologists, being part of the teams managing such pregnancies, should be well aware of the findings that may be encountered in infants of diabetic mothers. Timely, accurate, and proper radiological evaluation can reduce morbidity and mortality in these infants. The purpose of this essay is to illustrate the imaging findings in the various pathological conditions involving the major body systems in the offspring of women with diabetes

  8. Essays on Arbitrage and Market Liquidity

    DEFF Research Database (Denmark)

    Tomio, Davide

    The first essay investigates how credit risk, the risk that a bond issuer will default, affects bond market liquidity. Specifically, we depart from the current literature in that we analyze the direct and indirect channels through which credit risk affects market liquidity, rather than determining...... whether both are priced in the bond. We focus on the Italian sovereign bond market, which allows us to determine how central bank interventions affect the sensitivity of the liquidity provision by market makers to default risk. We motivate our empirical analysis with a simple model of a risk averse market...... maker, holding an inventory of a risky asset and setting her optimal marginal quotes (and, therefore, the optimal bid-ask spread), in the presence of margin constraints and borrowing costs. The margins, set by a clearing house, depend on the risk of the asset, as measured by the CDS spread...

  9. Jeremy Bentham's essay on "Paederasty". Part 2.

    Science.gov (United States)

    Crompton, L

    1978-01-01

    This is Part 2 of a transcription of Bentham's manuscript essay on "Paederasty" (1785), Part 1 of which appeared in Vol. 3, No. 4. In Part 1 Bentham argued for the decriminalization of sodomy and opposed the theories of Montesquieu and Voltaire as to its social dangers. In Part 2 Bentham speculates on its causes and alleges that the real reason such behavior is so severely punished is an irrational "antipathy" to pleasure generally and to sexual pleasure in particular. He discusses the danger of blackmail and false accusations and the punishment of lesbian acts, bestiality, and masturbation. Some miscellaneous related notes by Bentham are appended: these deal with religious fears based on the destruction of Sodom, the threat to population, the harshness of English naval law, and other topics.

  10. Pictorial Essay: Infants of diabetic mothers

    Directory of Open Access Journals (Sweden)

    Alorainy Ibrahim

    2010-01-01

    Full Text Available About 3 to 10% of pregnancies are complicated by glycemic control abnormalities. Maternal diabetes results in significantly greater risk for antenatal, perinatal, and neonatal morbidity and mortality, as well as congenital malformations. The number of diabetic mothers is expected to rise, as more and more of the obese pediatric female population in developed and some developing countries progresses to childbearing age. Radiologists, being part of the teams managing such pregnancies, should be well aware of the findings that may be encountered in infants of diabetic mothers. Timely, accurate, and proper radiological evaluation can reduce morbidity and mortality in these infants. The purpose of this essay is to illustrate the imaging findings in the various pathological conditions involving the major body systems in the offspring of women with diabetes

  11. Mathematical statistics essays on history and methodology

    CERN Document Server

    Pfanzagl, Johann

    2017-01-01

    This book presents a detailed description of the development of statistical theory. In the mid twentieth century, the development of mathematical statistics underwent an enduring change, due to the advent of more refined mathematical tools. New concepts like sufficiency, superefficiency, adaptivity etc. motivated scholars to reflect upon the interpretation of mathematical concepts in terms of their real-world relevance. Questions concerning the optimality of estimators, for instance, had remained unanswered for decades, because a meaningful concept of optimality (based on the regularity of the estimators, the representation of their limit distribution and assertions about their concentration by means of Anderson’s Theorem) was not yet available. The rapidly developing asymptotic theory provided approximate answers to questions for which non-asymptotic theory had found no satisfying solutions. In four engaging essays, this book presents a detailed description of how the use of mathematical methods stimulated...

  12. Essays on empirical industrial organization : Entry and innovation

    NARCIS (Netherlands)

    Fernandez Machado, Roxana

    2017-01-01

    The dissertation contains three essays on empirical industrial organization devoted to studying firms' strategic interaction in different settings. The first essay develops an entry model to address an important matter in the area of urban economics: the development of cities. In particular, it

  13. Cooperation, networks and emotions: Three essays in behavioral economics

    NARCIS (Netherlands)

    van Leeuwen, B.

    2015-01-01

    This thesis contains three essays that study how people behave in a social context. The first two essays are on cooperation and networks. Chapter 2 investigates a mechanism to facilitate public good provision in networks. It relies on the idea that people compete for attractive network positions (or

  14. Empirical essays on behavioral economics and lifecycle decisions

    NARCIS (Netherlands)

    Dillingh, Rik

    2016-01-01

    This dissertation consists of four empirical essays that study decisions on insurance, consumption and the accumulation and decumulation of wealth. The studies pay due attention to behavioral factors that may limit rationality, such as complexity and intertemporal choice. The first essay looks at

  15. A Crosscultural Analysis of Argumentative Strategies in Student Essays.

    Science.gov (United States)

    Kamimura, Taeko; Oi, Kyoko

    A study of essays on a single topic (capital punishment) written by 22 American high school students and 30 second-year Japanese college students investigated: cultural differences in organizational patterns in argumentative essays; comparative use of rational and affective appeals; differences in content of rational and affective appeals;…

  16. Writing anxiety: an affective filter for essay writing instruction among ...

    African Journals Online (AJOL)

    This study which adopted the descriptive research design investigated the relationship between writing anxiety and students' achievement in essay writing. SS2 Students from six schools in Ibadan Metropolis were used for the study. The instruments used were Essay Writing Achievement Test(r=0.81) and Writing Anxiety ...

  17. The future-essay as a design tool

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl; Kappel, Anne

    2007-01-01

    The aim of this paper is to present scenarios, photo-essays and future-essays as tools in communication, and as tools for clarifying the use of products in the future and the aesthetic qualities in the programme. In the design process, the programme is a description of the function, the condition...

  18. Essays and Explorations: Studies in Ideas, Language, and Literature.

    Science.gov (United States)

    Bloomfield, Morton W.

    Seventeen reprinted essays and an unpublished one are contained in this collection and organized under five headings: History of Ideas, Approaches to Medieval Literature, Chaucer and Fourteenth-Century English Literature, Language and Linguistics, and Essay-Reviews. Topics discussed include the origin of the concept of the Seven Cardinal Sins;…

  19. The Doctorate in Chemistry. Carnegie Essays on the Doctorate: Chemistry.

    Science.gov (United States)

    Breslow, Ronald

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  20. Essays in game theory and natural resource management

    NARCIS (Netherlands)

    Pham Do, K.H.

    2003-01-01

    This thesis presents a collection of essays in game theory with applications to environmental resource problems and their management. A major focus of these essays is related to coalitional games in which several classes of games, their properties and solution concepts are studied. Game theory is

  1. Reliability of Holistic Scoring for the 1985 MCAT Essays.

    Science.gov (United States)

    Mitchell, Karen J.; Anderson, Judith A.

    A pilot essay was included in the 1985 Spring and Fall administrations of the Medical College Admission Test. A sample of 320 of the essays written by Fall examinees who had expressed an interest in allopathic medicine was used to calculate interrater reliability estimates. Sixteen of 20 readers who had been trained by White's suggestions for…

  2. An interim report on the MCAT Essay Pilot Project.

    Science.gov (United States)

    Koenig, J A; Mitchell, K J

    1988-01-01

    Results from four pilot administrations of the Medical College Admission Test essay question are reported. Analyses focused on (a) the performance characteristics of sample groups differentiated by gender, size of hometown, race/ethnicity, and dominant language; (b) the relationships between essay scores and academic/demographic characteristics; and (c) the reliability of one 45-minute versus two 30-minute essays. No differences were found for examinees grouped by gender and size of home community. Mean differences among the racial/ethnic groups were explained largely by reading level differences. Differences in essay performance by language group were large and unexplained by reading level differences. No relationship was found between the essay score and the academic/demographic characteristics. Reliability estimates for two 30-minute essays were higher than for one 45-minute essay; however, the 30-minute period yielded writing of poorer quality. Test-retest reliabilities for the 45-minute topics will remain the focus of future studies as will performance by examinees for whom English is a second language. The impact of the essay on the selection process will also be assessed.

  3. Scaffolding for Second Language Writers: Producing an Academic Essay.

    Science.gov (United States)

    Cotterall, Sara; Cohen, Robin

    2003-01-01

    Describes how a group of intermediate learners of English were guided through the process of producing their first academic essays in English. The approach applied the concept of scaffolding to the academic writing process by proving flexible support for the learners throughout the writing of their essays. (Author/VWL)

  4. Metaphor of society (a sociological essay

    Directory of Open Access Journals (Sweden)

    Gennadii Vasil’evich Osipov

    2014-11-01

    Full Text Available The essay by Academician G.V. Osipov, who is the patriarch of Russian sociology, is dedicated to one of the most cognitive topics of modern sociology – identification of sociological metaphor as such and its application in research projects. This topic is avant-garde for the world sociological thought, and in Russia such kind of research is making its first steps. However, its future importance is difficult to overestimate. Sociological metaphor, if a methodology for its application is developed, can provide scientists with qualitatively new synthetic research tools. It can also bring together scientific structures and artifacts on the space of interdisciplinary and inter-subject borderland and give them qualitatively new intellectual and sensuous (system and mental technological capabilities for learning the surrounding world. The advantage of the following essay can be found in the fact that it is based on the objective analysis of the real embodiment of social metaphor in the work of art – a pictorial triptych “The Mystery of the 21st Century”. This is the first such experience in domestic sociological and artistic-painting practice. The authors of the final product are a scientist of great scientific and life experience and a young artist, who received in-depth sociological training and defended his Ph.D. in Sociology dissertation. But the main result of their collaboration is a product that combines scientific (sociological knowledge and insight and intuitive-creative artistic perception in a qualitatively new perception of the world and world outlook

  5. The future of the city. Essays; De toekomst van de stad. Essays

    Energy Technology Data Exchange (ETDEWEB)

    Uitermark, J.; Schinkel, W. [Erasmus Universiteit Rotterdam EUR, Rotterdam (Netherlands); Engelen, E. [Universiteit van Amsterdam UvA, Amsterdam (Netherlands); Raspe, O.; Hamers, D. [Planbureau voor de Leefomgeving PBL, Den Haag (Netherlands); Janssen, J.; Beunen, R. [Wageningen University WUR, Wageningen (Netherlands); Schutten, I. [Studio Iris Schutten, Den Haag (Netherlands); Mommaas, H. [Universiteit Tilburg, Telos, Brabants Centrum voor Duurzame Ontwikkeling, Tilburg (Netherlands); Tillie, N. [Landschapsarchitect en adviseur duurzaamheid, Technische Universiteit Delft TUD, Delft (Netherlands); Verheijen, M. [Hogeschool Rotterdam, Rotterdam (Netherlands); Schuilenburg, M. [Vrije Universiteit VU, Amsterdam (Netherlands); De Jong, J.D. [Rebond onderzoek en advies, Amsterdam (Netherlands); Van Steekelenburg, M. [Spatialplanning.com, Provinciehuis Zuid-Holland, Den Haag (Netherlands); Vermeulen, P. [Dienst Ruimtelijke Ordening Amsterdam, Amsterdam (Netherlands); De Waal, M. [The Public Matters, Amsterdam (Netherlands); Mulder, B. [Mandorla Consultancy, Bussum (Netherlands); Soeterbroek, F. [De Ruimtemaker, Utrecht (Netherlands); Wijma, J. [Programmabureau Regio Groningen-Assen, Groningen (Netherlands)

    2012-08-15

    The essays discuss nine tasks for the city. Each problem will be approached from two angles. The focus is on the relationship between governments and the self-resolving power in the city, the capacity of individuals, groups and organizations to change. Where In what cases does the self-resolving power of the city hamper? When is government intervention required? What is the role of connections between tasks, policies and groups? [Dutch] De essays gaan in op negen opgaven voor de stad. Elke opgave wordt vanuit twee invalshoeken belicht. Centraal staat de verhouding tussen overheden en zelfoplossend vermogen in de stad, de 'veranderkracht' van individuen, groepen en organisaties. Waar hapert het zelfoplossend vermogen van de stad? Wanneer is overheidsinterventie gewenst? Welke rol spelen verbindingen tussen opgaven, beleidssectoren en groepen daarbij?.

  6. The future of the city. Essays; De toekomst van de stad. Essays

    Energy Technology Data Exchange (ETDEWEB)

    Uitermark, J.; Schinkel, W. [Erasmus Universiteit Rotterdam EUR, Rotterdam (Netherlands); Engelen, E. [Universiteit van Amsterdam UvA, Amsterdam (Netherlands); Raspe, O.; Hamers, D. [Planbureau voor de Leefomgeving PBL, Den Haag (Netherlands); Janssen, J.; Beunen, R. [Wageningen University WUR, Wageningen (Netherlands); Schutten, I. [Studio Iris Schutten, Den Haag (Netherlands); Mommaas, H. [Universiteit Tilburg, Telos, Brabants Centrum voor Duurzame Ontwikkeling, Tilburg (Netherlands); Tillie, N. [Landschapsarchitect en adviseur duurzaamheid, Technische Universiteit Delft TUD, Delft (Netherlands); Verheijen, M. [Hogeschool Rotterdam, Rotterdam (Netherlands); Schuilenburg, M. [Vrije Universiteit VU, Amsterdam (Netherlands); De Jong, J. D. [Rebond onderzoek en advies, Amsterdam (Netherlands); Van Steekelenburg, M. [Spatialplanning.com, Provinciehuis Zuid-Holland, Den Haag (Netherlands); Vermeulen, P. [Dienst Ruimtelijke Ordening Amsterdam, Amsterdam (Netherlands); De Waal, M. [The Public Matters, Amsterdam (Netherlands); Mulder, B. [Mandorla Consultancy, Bussum (Netherlands); Soeterbroek, F. [De Ruimtemaker, Utrecht (Netherlands); Wijma, J. [Programmabureau Regio Groningen-Assen, Groningen (Netherlands)

    2012-08-15

    The essays discuss nine tasks for the city. Each problem will be approached from two angles. The focus is on the relationship between governments and the self-resolving power in the city, the capacity of individuals, groups and organizations to change. Where In what cases does the self-resolving power of the city hamper? When is government intervention required? What is the role of connections between tasks, policies and groups? [Dutch] De essays gaan in op negen opgaven voor de stad. Elke opgave wordt vanuit twee invalshoeken belicht. Centraal staat de verhouding tussen overheden en zelfoplossend vermogen in de stad, de 'veranderkracht' van individuen, groepen en organisaties. Waar hapert het zelfoplossend vermogen van de stad? Wanneer is overheidsinterventie gewenst? Welke rol spelen verbindingen tussen opgaven, beleidssectoren en groepen daarbij?.

  7. Chocolate das bagas e clorose foliar: anomalia da videira causada por deficiência de boro Internal browning ("chocolate" and leaf chlorosis of the 'pink Niagara' grafe, a boron deficiency anomaly

    Directory of Open Access Journals (Sweden)

    Hugo Kuniyuki

    1985-01-01

    Full Text Available A anomalia do cultivar de videira Niagara Rosada, caracterizada por sintomas de clorose nas folhas, chocolate das bagas e cachos malformados, não é de natureza virótica, de acordo com resultados de testes de transmissão e de perpetuação. Essa anomalia, presente em áreas definidas de alguns vinhedos de Indaiatuba e Jundiaí (SP, está associada à deficiência nutricional de boro. O teor médio de boro em amostras de plantas afetadas de 'Niagara Rosada' (18 ppm no limbo e 7 ppm nos frutos foi menor do que nas de plantas normais (24 ppm no limbo e 10 ppm nos frutos das mesmas plantaçoes; um material coletado de um vinhedo bastante afetado mostrou 13 e 1 ppm respectivamente no limbo e nos frutos de plantas deficientes contra 20 e 6 ppm nos de plantas sem sintomas. Amostras de três vinhedos vizinhos sem essa anomalia apresentaram um teor médio de 35 ppm no limbo. As do porta-enxerto 'Traviú' com clorose e sem clorose mostraram 16 ppm e 43 ppm de boro respectivamente. A aplicação de bórax, nas doses de 5, 10 e 20g por planta, 1ogo após a poda de inverno, ou pulverização de ácido bórico nas concentraçoes de 0,3% e 0,6% sobre a folhagem, durante o início do florescimento e durante a fase de uva chumbinho, permitiram controlar a anomalia nas condições de campo. Foi notada resposta favorável por um ciclo vegetativo, pelo menos, indicando controle por efeito residual de uma aplicação.The 'pink Niagara' grape (V. labrusca L. x V. vinifera L. anomaly characterized by leaf chlorosis and "chocolate" (internal browning of the young fruit, at first thought to be a virus disease, has been found to be a result of boron deficiency. The anomaly was first recorded in 1974. It occurs in patches in vineyards of Indaiatuba and Jundiaí, two grape-growing counties of the State of São Paulo, Brazil. Affected plants show yellowing between the primary and secondary veins of the upper leaves and malformed clusters, with normal-sized berries and

  8. Exposure to misoprostol and hormones during pregnancy and risk of congenital anomalies Exposição ao misoprostol e hormônios durante a gravidez e risco de anomalia congênita

    Directory of Open Access Journals (Sweden)

    Tatiane da Silva Dal Pizzol

    2008-06-01

    Full Text Available This study evaluated the association between use of misoprostol and other drugs to induce menstruation, and congenital anomalies. A sample of 4,856 pregnant women 20 years and older were enrolled consecutively in prenatal services in the Unified National Health System, in six Brazilian State capitals. Data on socio-demographics and use of medicines were obtained using an interview from the 21st to 28th week of pregnancy. Other data, including information on delivery and diagnosis of congenital anomalies by the attending neonatal physician were obtained from patient charts. Potential confounders were adjusted by logistic regression. Use of drugs to induce menstruation was reported by 707 women (14.6%, of whom 120 (17% reported use of misoprostol. After adjusting for the study center, a positive association was observed between misoprostol and congenital anomalies (OR = 2.64; 95%CI: 1.03-6.75; a positive association was also observed for sex hormones (OR = 2.24; 95%CI: 1.06-4.74. The results suggest that the use of misoprostol or sex hormones during pregnancy increases the risk of congenital anomalies.Este estudo avalia a associação do uso do misoprostol e de outros produtos utilizados para induzir a menstruação com anomalia congênita. Foram arroladas consecutivamente 4.856 mulheres com vinte anos de idade ou mais, procedentes de serviços de pré-natal do Sistema Único de Saúde em seis capitais brasileiras. Dados sócio-demográficos e o uso de medicamentos foram obtidos por meio de entrevista, entre a 21ª e a 28ª semanas de gestação. Outros dados, incluindo informações sobre o parto e o diagnóstico de anomalia congênita, realizado pelo médico que assistiu o recém-nascido, foram obtidos no prontuário. Potenciais confundidores foram ajustados por meio de regressão logística. O uso de produtos para induzir a menstruação foi relatado por 707 gestantes (14,6%, das quais 120 (17% referiram-se ao misoprostol. Após ajustamento

  9. Obtenção de anticorpos policlonais contra proteínas presentes em plantas afetadas pela anomalia declínio dos citros Production of antibodies against proteins expressed in plants affected by citrus blight

    Directory of Open Access Journals (Sweden)

    Sanzio Carvalho Lima Barrios

    2006-10-01

    Full Text Available O declínio dos citros, uma anomalia de etiologia desconhecida, continua sendo um dos entraves para o setor citrícola, uma vez que não existem medidas de prevenção e controle para as plantas acometidas pela anomalia. Para a caracterização e estudo da anomalia, muita ênfase tem sido dada à mudança na expressão gênica de plantas afetadas, que culmina no acúmulo de proteínas. Proteínas totais extraídas dos vasos do xilema de raízes de plantas afetadas pela anomalia, quando separadas por eletroforese no sistema SDS-PAGE 12,5%, apresentam um perfil eletroforético contendo proteínas com massas moleculares de cerca de 21, 23, 31 e 42 kDa, sendo que plantas consideradas sadias apresentam proteínas de 21, 31 e 42 kDa. Com este trabalho objetivou-se obter anticorpos contra essas proteínas, bem como a titulação adequada para os mesmos. Duas inoculações subcutâneas foram realizadas em coelhos, espaçadas de 15 dias, ambas usando cerca de 120 µg de proteína isolada, sendo que cada coelho recebeu uma proteína específica, visando à produção de anticorpos. A primeira sangria foi realizada aos 21 dias após a primeira inoculação e as demais semanalmente. A técnica Western Blotting foi realizada para a confirmação da especificidade dos anticorpos, bem como para determinação das respectivas titulações. O título 1:1500 foi aquele que proporcionou maior especificidade para as proteínas de 21, 23 e 31 kDa. Para a proteína de 42 kDa a melhor titulação foi de 1:3000. Estes anticorpos poderão ser utilizados em estudos para caracterização dessas proteínas.Citrus blight, an abnormality of unknown etiology, is a major problem in citrus production, since there are no prevention and control measures to be taken. In order to characterize this abnormality, changes in genetic expression of the affected plants have exhaustedly been studied. Crude proteec extract obtained from the root xylem of the abnormal plants, when separated

  10. ARL6IP6, a susceptibility locus for ischemic stroke, is mutated in a patient with syndromic Cutis Marmorata Telangiectatica Congenita.

    Science.gov (United States)

    Abumansour, Iman S; Hijazi, Hadia; Alazmi, Anas; Alzahrani, Fatma; Bashiri, Fahad A; Hassan, Hamdy; Alhaddab, Mohammed; Alkuraya, Fowzan S

    2015-08-01

    Cutis Marmorata Telangiectatica Congenita (CMTC) is a congenital localized or generalized vascular anomaly, usually sporadic in occurrence. It can be associated with other cutaneous or systemic manifestations. About 300 cases have been reported. The molecular etiology remains largely unknown. The main purpose of this study is to delineate the molecular basis for a syndromic CMTC phenotype in a consanguineous Saudi family. Clinical phenotyping including detailed neurological imaging, followed by autozygosity mapping and trio whole exome sequencing (WES) are also studied. We have identified a homozygous truncating mutation in ARL6IP6 as the likely cause of a syndromic form of CMTC associated with major dysmorphism, developmental delay, transient ischemic attacks and cerebral vascular malformations. This gene was previously implicated by genome wide association study (GWAS) as a susceptibility locus to ischemic stroke in young adults. We identify ARL6IP6 as a novel candidate gene for a syndromic form of CMTC. This suggests that ischemic stroke or transient ischemic attacks (TIA) may represent, at least in some cases, the mild end of a phenotypic spectrum that has at its severe end autosomal recessive CMTC. This finding contributes to a growing appreciation of the continuum of Mendelian and common complex diseases.

  11. Loss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita.

    Science.gov (United States)

    Xue, Shifeng; Maluenda, Jérôme; Marguet, Florent; Shboul, Mohammad; Quevarec, Loïc; Bonnard, Carine; Ng, Alvin Yu Jin; Tohari, Sumanty; Tan, Thong Teck; Kong, Mung Kei; Monaghan, Kristin G; Cho, Megan T; Siskind, Carly E; Sampson, Jacinda B; Rocha, Carolina Tesi; Alkazaleh, Fawaz; Gonzales, Marie; Rigonnot, Luc; Whalen, Sandra; Gut, Marta; Gut, Ivo; Bucourt, Martine; Venkatesh, Byrappa; Laquerrière, Annie; Reversade, Bruno; Melki, Judith

    2017-04-06

    Arthrogryposis multiplex congenita (AMC) is a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. Through genetic mapping of disease loci and whole-exome sequencing in four unrelated multiplex families presenting with severe AMC, we identified biallelic loss-of-function mutations in LGI4 (leucine-rich glioma-inactivated 4). LGI4 is a ligand secreted by Schwann cells that regulates peripheral nerve myelination via its cognate receptor ADAM22 expressed by neurons. Immunolabeling experiments and transmission electron microscopy of the sciatic nerve from one of the affected individuals revealed a lack of myelin. Functional tests using affected individual-derived iPSCs showed that these germline mutations caused aberrant splicing of the endogenous LGI4 transcript and in a cell-based assay impaired the secretion of truncated LGI4 protein. This is consistent with previous studies reporting arthrogryposis in Lgi4-deficient mice due to peripheral hypomyelination. This study adds to the recent reports implicating defective axoglial function as a key cause of AMC. Copyright © 2017 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

  12. Essays on energy derivatives pricing and financial risk management =

    Science.gov (United States)

    Madaleno, Mara Teresa da Silva

    This thesis consists of an introductory chapter (essay I) and five more empirical essays on electricity markets and CO2 spot price behaviour, derivatives pricing analysis and hedging. Essay I presents the structure of the thesis and electricity markets functioning and characteristics, as well as the type of products traded, to be analyzed on the following essays. In the second essay we conduct an empirical study on co-movements in electricity markets resorting to wavelet analysis, discussing long-term dynamics and markets integration. Essay three is about hedging performance and multiscale relationships in the German electricity spot and futures markets, also using wavelet analysis. We concentrate the investigation on the relationship between coherence evolution and hedge ratio analysis, on a time-frequency-scale approach, between spot and futures which conditions the effectiveness of the hedging strategy. Essays four, five and six are interrelated between them and with the other two previous essays given the nature of the commodity analyzed, CO2 emission allowances, traded in electricity markets. Relationships between electricity prices, primary energy fuel prices and carbon dioxide permits are analyzed on essay four. The efficiency of the European market for allowances is examined taking into account markets heterogeneity. Essay five analyzes stylized statistical properties of the recent traded asset CO2 emission allowances, for spot and futures returns, examining also the relation linking convenience yield and risk premium, for the German European Energy Exchange (EEX) between October 2005 and October 2009. The study was conducted through empirical estimations of CO2 allowances risk premium, convenience yield, and their relation. Future prices from an ex-post perspective are examined to show evidence for significant negative risk premium, or else a positive forward premium. Finally, essay six analyzes emission allowances futures hedging effectiveness, providing

  13. Back to the future: eugenics--a bibliographic essay.

    Science.gov (United States)

    Cullen, David

    2007-01-01

    The following essay is a review of the literature about the American eugenics movement produced by scholars over the last fifty years. The essay provides an explanation for today's renewed interest in the subject and for why the science of eugenics remains relevant to contemporary society. The essay examines the catalyst to re-examine the eugenics movement, the influence of Darwinian thought upon its development, the political and institutional support for its growth, the relationship between eugenics, sterilization, and sex, and how the twentieth-century promises of the science of better breeding was a precursor to the twenty-first-century promise of genetic engineering.

  14. Writing an academic essay: a practical guide for nurses.

    Science.gov (United States)

    Booth, Y

    Writing academic essays can be a major hurdle and source of anxiety for many students. Fears and misconceptions relating to this kind of writing can be dispelled if the task is approached in a logical and systematic manner. This article outlines the key steps involved in successfully completing an essay and provides some practical tips to facilitate critical and analytical writing. These steps are: analysing the task; exploring the subject; planning the essay; writing the account; and revising the drafts. Although this process is challenging, academic writing is a means of developing both personally and professionally.

  15. "ESSAY ON CI" BY LI QINGZHAO

    Directory of Open Access Journals (Sweden)

    Anna Dashchenko

    2016-10-01

    Full Text Available The article presents the first Russian translation of "Essay on Ci" with detailed comments. It was written by the outstanding Chinese poetess Li Qingzhao and considered to be the first theoretical treatise dedicated to genre ci. The article revealed that the poetess used three strategies to make a genre demarcation: to legitimise, dichotomise and historicise. To legitimise means to justify that ci is a genre of poetry by identifying the same traits with official poetry shi (e.g. using the classical quotations and allusions. To dichotomise is to determine a core element of genre and oppose it to the other element identifying the similar genre (e.g. music separates ci from shi. To historicise is to develop or discover the unique historical past (e.g. the source of ci is in antiquity. The article also examined the strategy to invent classics: Li Qingzhao wrote the apophatic history of genre ci pointing not to the merits but weaknesses of her predecessors.

  16. Latin America: Essays Interpretating Colonial Legacy

    Directory of Open Access Journals (Sweden)

    María Pia López

    2013-12-01

    Full Text Available A large part of the Latin–American literature of the 19th and 20th century tried to deal with the national question intertwining different dimensions: the weight of colonial legacy, the cultural peculiarity of the nation and the inner relations between social classes and ethnic groups. Thinking the nation implied, in any case, to think the difference and the conflict with others, as well as the inner conflict and the logic of local colonialism. Analyzing some of these essays that played a central role in such process of recasting the origin of the nation, the author moves around three main axes: the formulation of dualist writings (colonial/national; white /indigenous; civilization/wilderness, the issue of language (the language inherited from the colonial experience versus the multilingual nature of indigenous Latin American societies, and the hypothesis about the birth of the nation – appointed to different groups – and its normal functioning as legitimization of the order sprung from independences.

  17. The Test of Practice–An Essay

    Directory of Open Access Journals (Sweden)

    Lars Løvlie

    2017-02-01

    Full Text Available This essay starts in medias res, in the puzzling reappearance of the classical metaphor of Bildung as the transformation of man’s “first” animal nature into the “second” cultivated one. I call it the two-natures metaphor. I think it misrepresents children by prescribing form rather than asking what actually takes form in the child’s mind—in his/her relationship with adults. It made me wonder whether this mistake also lingers on in the current discourse on education. I then turn to aspects of John Dewey’s subtle and revolutionary critique of the classical theory of formation, but also to make the controversial point that he, too, seems to miss the importance of the child’s internal point of view. The importance of the subjective life of the child is suggested first by reinscribing Rousseau and Kant into the intersubjective theories of Hegel and Dewey; second, by reference to recent studies in developmental psychology that offer detailed and in-depth descriptions of our relationship with children. My basic point of departure is the existential encounters between children and adults, for example, as part of classroom practices. The title has a double connotation. It means that theory must be taken as the measure of practice. It means, too, that practice must work as the measure of theory. I will, in the main, try and pursue the last course.

  18. Rhetorical, Metacognitive, and Cognitive Strategies in Teacher Candidates’ Essay Writing

    Directory of Open Access Journals (Sweden)

    Claudio Díaz Larenas

    2017-07-01

    Full Text Available This paper reports on a study about the rhetoric, metacognitive, and cognitive strategies pre-service teachers use before and after a process-based writing intervention when completing an argumentative essay. The data were collected through two think-aloud protocols while 21 Chilean English as a foreign language pre-service teachers completed an essay task. The findings show that strategies such as summarizing, reaffirming, and selecting ideas were only evidenced during the post intervention essay, without the use of communication and socio-affective strategies in either of the two essays. All in all, a process-based writing intervention does not only influence the number of times a strategy is used, but also the number of students who employs strategies when writing an essay—two key considerations for the devising of any writing program.

  19. Essays on Public Documents and Government Policies (3).

    Science.gov (United States)

    Morehead, Joe

    1986-01-01

    Eight essays on government documents examine a variety of subjects--the publication "Policy and Supporting Positions," Supreme Court and separation of powers rulings, private legislation, environmental information, publications of the Department of Education, physical fitness, and national cemeteries. (EM)

  20. Biotechnology essay competition: biotechnology and sustainable food practices.

    Science.gov (United States)

    Peng, Judy; Schoeb, Helena; Lee, Gina

    2013-06-01

    Biotechnology Journal announces our second biotechnology essay competition with the theme "biotechnology and sustainable food practices", open to all undergraduate students. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Technology and Military Doctrine. Essays on a Challenging Relationship

    National Research Council Canada - National Science Library

    Holley, I

    2004-01-01

    .... In these essays, Holley primarily addresses the need for the Air Force to adapt its doctrine and the processes of formulating and disseminating that guidance as the technology of air and space warfare improves. Dr...

  2. Librarianship and literature essays in honour of Jack Pafford

    CERN Document Server

    Milne, A T

    2014-01-01

    These essays are produced in honour of the seventieth birthday of Dr J. H. Pafford, Goldsmith's Librarian of the University of London from 1945 to 1967, and reflect his interests in librarianship, textual editing and local history.

  3. Essays on the Determinants of Prosocial Behavior in Singapore

    OpenAIRE

    Lim, Daniel

    2015-01-01

    Previous research has sought to explain why people engage in prosocial behavior and undertake activities that are costly to themselves and mostly benefit others, such as volunteering and donating. My dissertation comprises three essays that collectively explore the determinants of prosocial behavior and leverages insights from behavioral economics to design interventions to nudge people to behave more prosocially. The first essay is an observational study that examines how rapid demographic c...

  4. Four essays on market power in energy economics

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Petter Vegard

    2008-07-01

    Market power in energy markets is discussed intensively in both academic and public arenas. There has been an intense energy debate on market power at least since the Organization of Petroleum Exporting Countries (OPEC) exercised its market power and caused the 'oil crisis' of the 1970s, and again following the deregulation of electricity markets at the beginning of the 1990s. However, this debate is not new. In 1911, for example, the US Supreme Court divided Standard Oil into 34 separate companies using antitrust law. With increasing energy prices and the ongoing process of liberalization of electricity markets throughout the world, the topic is still relevant for future markets. The four essays in this dissertation discuss specific aspects of market power in energy markets. The first essay concerns the crude oil market, and the remaining three essays relate to market power in the Nordic and Norwegian electricity markets. In the first essay, a multi-equation dynamic econometric model tests whether the behaviour of OPEC, as a whole or as different subgroups, is consistent with the behaviour of dominant producers in the world crude oil market. The second essay is a theoretical work that introduces uncertainty in inflow to the discussion of market power in hydropower markets by analysing the effects of uncertainty in inflow on market performance under alternative assumptions about market structure. In the third essay, high-frequency data are used to analyse how price signals from the spot market affect end-user demand in the Norwegian and Swedish electricity markets. Finally, in the fourth essay, retailer and household behaviour in the Norwegian electricity market are analysed using detailed information on prices and other market characteristics. In the following section, I provide highlights from a general discussion of market power in order to set the essays included in this dissertation in context. (Author). refs., figs., tabs

  5. Essays on oil: project evaluation and investment impact

    OpenAIRE

    Bagh, Dima

    2015-01-01

    This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University London This thesis contains three essays related to fixed investment and crude oil. The first essay examines the implications of building a cross-border oil infrastructure project within the context of the bargaining problem (the Nash bargaining solution, and the alternating offer bargain of Rubinstein). We examine the viability of the Baku-Tbilisi-Ceyhan oil pipeline project, which is empl...

  6. Essays in Industrial Organization: Intermediation, Marketing, and Strategic Pricing

    OpenAIRE

    Wismer, Sebastian

    2014-01-01

    This dissertation deals with certain business strategies that have become particularly relevant with the spread and development of new information technologies. The introduction explains the motivation, discusses different ways of defining the term "two-sided market", and briefly summarizes the subsequent essays. The first essay examines the effects of product information on the pricing and advertising decision of a seller who offers an experience good whose quality is unknown to cons...

  7. Essays on incentives and pro-environmental behaviour

    OpenAIRE

    De Martino, Samantha

    2017-01-01

    This thesis consists of four self-contained essays at the nexus of applied microeconomics, behavioural economics, and environmental economics. In the essays of the thesis, I use field experiments and econometric tools to examine the impact of monetary and non monetary incentives for behavioural change during resource scarcity. I use methods of eliciting intrinsic motivations and then empirically test theories on the interaction of intrinsic motivation and extrinsic incentives. Specifically I ...

  8. An RNA-splicing mutation (G{sup +51VS20}) in the Type II collagen gene (COL2A1) in a family with spondyloepiphyseal dysplasia congenita

    Energy Technology Data Exchange (ETDEWEB)

    Tiller, G.E.; Polumbo, P.A. [Vanderbilt Univ. School of Medicine, Nashville, TN (United States); Weis, M.A.; Eyre, D.R. [Univ. of Washington, Seattle, WA (United States); Gruber, H.E.; Rimoin, D.L.; Cohn, D.H. [Cedars-Sinai Medical Center, Los Angeles, CA (United States)]|[Univ. of California School of Medicine, Los Angeles, CA (United States)

    1995-02-01

    Defects in type II collagen have been demonstrated in a phenotypic continuum of chondrodysplasias that includes achondrogenesis II, hypochondrogenesis, spondyloepiphyseal dysplasia congenita (SEDC), Kniest dysplasia, and Stickler syndrome. We have determined that cartilage from a terminated fetus with an inherited form of SEDC contained both normal {alpha}1(II) collagen chains and chains that lacked amino acids 256-273 of the triple-helical domain. PCR amplification of this region of COL2A1, from genomic DNA, yielded products of normal size, while amplification of cDNA yielded a normal sized species and a shorter fragment missing exon 20. Sequence analysis of genomic DNA from the fetus revealed a G{yields}T transversion at position +5 of intron 20; the affected father was also heterozygous for the mutation. Allele-specific PCR and heteroduplex analysis of a VNTR in COL2A1 independently confirmed the unaffected status of a fetus in a subsequent pregnancy. Thermodynamic calculations suggest that the mutation prevents normal splicing of exon 20 by interfering with binding of U{sub 1} small-nuclear RNA to pre-mRNA, thus leading to skipping of exon 20 in transcripts from the mutant allele. Electron micrographs of diseased cartilage showed intracellular inclusion bodies, which were stained by an antibody to {alpha}1(II) procollagen. Our findings support the hypothesis that {alpha}-chain length alterations that preserve the Gly-X-Y repeat motif of the triple helix result in partial intracellular retention of {alpha}1(II) procollagen and produce mild to moderate chondrodysplasia phenotypes. 50 refs., 6 figs., 1 tab.

  9. Disceratose congênita: relato de caso e revisão da literatura Dyskeratosis congenita: case report and literature review

    Directory of Open Access Journals (Sweden)

    Sílvia Pimenta de Carvalho

    2003-10-01

    Full Text Available A disceratose congênita é doença hereditária rara, caracterizada pela tríade de pigmentação reticulada da pele, distrofia ungueal e leucoceratose em mucosas. Alterações dentárias, gastrintestinais, geniturinárias, neurológicas, oftalmológicas, pulmonares e esqueléticas associadas têm sido relatadas. A falência medular é a principal causa de morte precoce e também é descrita predisposição para doenças malignas. Afeta principalmente homens, e reconhecem-se formas recessivas ligadas ao X, autossômicas dominantes e recessivas. Relata-se o caso de uma criança do sexo masculino, que apresentava a tríade clássica das lesões sem antecedentes familiares. Faz-se revisão da literatura com o objetivo de enfatizar a necessidade do acompanhamento médico multidisciplinar, de modo a permitir diagnóstico precoce das possíveis complicações.Dyskeratosis congenita is an inherited disease characterised by the triad of abnormal skin pigmentation, nail dystrophy and mucosal leukoplakia. Non-cutaneous abnormalities (dental, gastrointestinal, genitourinary, neurological, ophthalmic, pulmonary and skeletal have also been reported. Bone marrow failure is the main cause of early mortality, with an additional predisposition to malignancy. Men are more affected than women and X-linked recessive, autosomal dominant and autosomal recessive forms of the disease are recognised. We report a case of a male child who presented the classic triad of lesions, without familial cases. A review of the literature is also made, emphasizing the importance of a multidisciplinary approach, which is fundamental for an early diagnosis of the complications.

  10. ZC4H2 Mutations Are Associated with Arthrogryposis Multiplex Congenita and Intellectual Disability through Impairment of Central and Peripheral Synaptic Plasticity

    Science.gov (United States)

    Hirata, Hiromi; Nanda, Indrajit; van Riesen, Anne; McMichael, Gai; Hu, Hao; Hambrock, Melanie; Papon, Marie-Amélie; Fischer, Ute; Marouillat, Sylviane; Ding, Can; Alirol, Servane; Bienek, Melanie; Preisler-Adams, Sabine; Grimme, Astrid; Seelow, Dominik; Webster, Richard; Haan, Eric; MacLennan, Alastair; Stenzel, Werner; Yap, Tzu Ying; Gardner, Alison; Nguyen, Lam Son; Shaw, Marie; Lebrun, Nicolas; Haas, Stefan A.; Kress, Wolfram; Haaf, Thomas; Schellenberger, Elke; Chelly, Jamel; Viot, Géraldine; Shaffer, Lisa G.; Rosenfeld, Jill A.; Kramer, Nancy; Falk, Rena; El-Khechen, Dima; Escobar, Luis F.; Hennekam, Raoul; Wieacker, Peter; Hübner, Christoph; Ropers, Hans-Hilger; Gecz, Jozef; Schuelke, Markus; Laumonnier, Frédéric; Kalscheuer, Vera M.

    2013-01-01

    Arthrogryposis multiplex congenita (AMC) is caused by heterogeneous pathologies leading to multiple antenatal joint contractures through fetal akinesia. Understanding the pathophysiology of this disorder is important for clinical care of the affected individuals and genetic counseling of the families. We thus aimed to establish the genetic basis of an AMC subtype that is associated with multiple dysmorphic features and intellectual disability (ID). We used haplotype analysis, next-generation sequencing, array comparative genomic hybridization, and chromosome breakpoint mapping to identify the pathogenic mutations in families and simplex cases. Suspected disease variants were verified by cosegregation analysis. We identified disease-causing mutations in the zinc-finger gene ZC4H2 in four families affected by X-linked AMC plus ID and one family affected by cerebral palsy. Several heterozygous females were also affected, but to a lesser degree. Furthermore, we found two ZC4H2 deletions and one rearrangement in two female and one male unrelated simplex cases, respectively. In mouse primary hippocampal neurons, transiently produced ZC4H2 localized to the postsynaptic compartment of excitatory synapses, and the altered protein influenced dendritic spine density. In zebrafish, antisense-morpholino-mediated zc4h2 knockdown caused abnormal swimming and impaired α-motoneuron development. All missense mutations identified herein failed to rescue the swimming defect of zebrafish morphants. We conclude that ZC4H2 point mutations, rearrangements, and small deletions cause a clinically variable broad-spectrum neurodevelopmental disorder of the central and peripheral nervous systems in both familial and simplex cases of both sexes. Our results highlight the importance of ZC4H2 for genetic testing of individuals presenting with ID plus muscle weakness and minor or major forms of AMC. PMID:23623388

  11. Energy resources and the environment. [6 essays

    Energy Technology Data Exchange (ETDEWEB)

    Lenihan, J; Fletcher, W W [eds.

    1975-01-01

    Exploitation of energy has some impact on the environment. Six essays are presented to examine the variety of problems: (1) Sir Samuel Curran, in Energy and the Needs of Man, concludes that techniques to produce new energy sources will be found, bur conservation and the population explosion must be seriously examined; (2) Dr. Earl Cook, in Flow of Energy Through Technological Society, shows where energy comes from, how it is used and how it returns to the environment; he emphasizes the inefficiency of many energy conversion processes in consequence of the Second law of Thermodynamics; (3) Dr. Andrew Parteous, in Economical Use of Energy and Materials, explains energy not only used in heating, lighting, and transport, but in industry; his accounting of energy shows waste, and he stresses recycling and recovering the energy in domestic waste; (4) Sir Frank McFadzean, in Energy--the International Scene, examines the interplay of economics, technology, and politics in the oil industry; he suggests that more mature international leadership is needed to overcome the current difficulties facing producers and consumers; (5) J. D. Dunster, in The Atom and the Environment, examines the environmental impact of nuclear energy where the safety standards are more strenuous, but are feared more; he is a proponent of nuclear energy, but says an overall energy policy, balancing environmental factors against economic and political considerations, is needed; Dr. B. J. Brinkworth, in Direct Use of Solar Energy, reminds us that the Sun is the ultimate source of energy, and says solar energy can be exploited globally without damaging the environment. (MCW)

  12. Essays on U.S. energy markets

    Science.gov (United States)

    Brightwell, David A.

    2008-04-01

    This dissertation examines three facets of U.S. energy use and policy. First, I examine the Gulf Coast petroleum refining industry to determine the structure of the industry. Using the duality between cost-minimization and production functions, I estimate the demand for labor to determine the underlying production function. The results indicate that refineries have become more capital intensive due to the relative price increase of labor. The industry has consolidated in response to higher labor costs and costs of environmental compliance. Next, I examine oil production in the United States. An empirical model based on the theoretical framework of Pindyck is used to estimate production. This model differs from previous research by using state level data rather than national level data. The results indicate that the production elasticity with respect to reserves and the price elasticity of supply are both inelastic in the long run. The implication of these findings is that policies designed to increase domestic production through subsidies, tax breaks, or royalty reductions will likely provide little additional oil. We simulate production under three scenarios. In the most extreme scenario, prices double between 2005 and 2030 while reserves increase by 50%. Under this scenario, oil production in 2030 is approximately the same as the 2005 level. The third essay estimates demand for fossil fuels in the U.S. and uses these estimates to forecast CO2 emissions. The results indicate that there is almost no substitution from one fossil fuel to another and that all three fossil fuels are inelastic in the long run. Additionally, all three fuels respond differently to changes in GDP. The result of the differing elasticities with respect to GDP is that the energy mix has changed over time. The implication for forecasting CO2 emissions is that models that cannot distinguish changes in the energy mix are not effective in forecasting CO2 emissions.

  13. Essays on information disclosure and the environment

    Science.gov (United States)

    Mathai, Koshy

    The essays in this dissertation study information disclosure and environmental policy. The first chapter challenges the longstanding result that firms will, in general, voluntarily disclose information about product quality, in light of the unrealism of the assumption, common to much of the literature, that consumers are identical. When this assumption is relaxed, an efficiency-enhancing role may emerge for disclosure regulation, insofar as it can improve information provision and thus help protect consumers with "moderately atypical" preferences. The paper also endogenizes firms's choice of quality and suggests that disclosure regulation may also raise welfare indirectly, by inducing firms to improve product quality. The second chapter explores the significance of policy-induced technological change (ITC) for the design of carbon-abatement policies. The paper considers both R&D-based and learning-by-doing-based knowledge accumulation, examining each specification under both a cost-effectiveness and a benefit-cost policy criterion. We show analytically that the presence of ITC generally implies a lower profile of optimal carbon taxes, a shifting of abatement effort into the future (in the R&D scenarios), and an increase in the scale of abatement (in the benefit-cost scenarios). Numerical simulations indicate that the impact of ITC on abatement timing is very slight, but the effects on costs, optimal carbon taxes, and cumulative abatement can be large. The third chapter uses a World Bank dataset on Chinese state-owned enterprises to estimate price elasticities of industrial coal demand. A simple coal-demand equation is estimated in many forms, and significant price sensitivity is almost always found: the own-price elasticity is estimated to be roughly -0.5. A cost-function/share-equation system is also estimated, and although the function is frequently ill-behaved, indicating that firms may not be minimizing costs, the elasticity estimates again are large and

  14. Anomalias e prognóstico fetal associados à translucência nucal aumentada e cariótipo anormal Fetal abnormalities and prognosis associated with increased nuchal translucency and abnormal karyotype

    Directory of Open Access Journals (Sweden)

    Fátima Aparecida Targino Saldanha

    2009-01-01

    Full Text Available OBJETIVO: Descrever a frequência de anomalias cromossômicas em fetos com translucência nucal (TN aumentada, e a frequência de malformações estruturais, a evolução e o resultado da gestação nos fetos com TN aumentada e cariótipo anormal. MÉTODOS: Estudo retrospectivo envolvendo 246 casos com medida da TN acima do percentil 95º para a idade gestacional, com cariótipo fetal conhecido ou avaliação clínica das crianças no período pós-natal. Os casos foram acompanhados no setor de Medicina Fetal do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. RESULTADOS: O resultado do cariótipo fetal esteve alterado em 14,2% dos casos. O acompanhamento dessas gestações revelou anormalidade estruturais em 80,8% dos fetos, sendo as anormalidades cardíacas as mais comuns (61,5%. Resultados gestacionais adversos, como abortamento, óbitos intraútero e neonatal ocorreram em 76,5% dos fetos. CONCLUSÃO: Translucência nucal aumentada, entre 11 - 13 semanas e 6 dias, é importante marcador de anomalias cromossômicas fetais e malformações estruturais fetais, principalmente cardíacas. Diante deste achado, há aumento do risco de abortamento, óbito intrauterino e neonatal para estas gestações.OBJECTIVES: This study aimed to evaluate the incidence of chromosomal abnormalities in fetuses with increased nuchal translucency (NT measurement. Incidence of structural abnormalities and pregnancy outcome was also described in fetuses with increased NT and abnormal karyotype. METHODS: This was a retrospective study involving 246 fetuses with increased NT and known karyotype followed at the Fetal Medicine Unit, Hospital das Clínicas, São Paulo University Medical School. RESULTS: Fetal karyotype was abnormal in 14.2% of the cases. Ultrasound anomaly scan and specialized echocardiographic studies in these cases showed fetal structural abnormalities in 80.8% and cardiac defects were found in 61.5% of the fetuses. Pregnancy

  15. Hematology, micronuclei and nuclear abnormalities in fishes from São Francisco river, Minas Gerais state, Brazil = Hematologia, micronúcleos e anomalias nucleares em peixes do rio São Francisco, Estado de Minas Gerais, Brasil

    Directory of Open Access Journals (Sweden)

    Robson Seriani

    2011-01-01

    Full Text Available This study aimed to determine the variables leukocytary, erythrocytary, frequency of micronuclei and nuclear abnormalities in peripheral erythrocytes of Prochilodus argenteus, Pimelodus maculatus and Myleus micans from São Francisco river basin, Minas Gerais State, during the summer and winter. Thrombocytes, hematocrit and leukocyte of P.argenteus series, was influenced by climatic conditions. In P. maculatus, not were significant differences for all leukocytes and thrombocytes. In M. micans, values are unprecedented in the literature, with MCV and absolute number of leukocytes found superior to other species of the family Characidae. The frequency of micronuclei and nuclear abnormalities in erythrocytes, the three species not showed seasonal differences between the sites. However, the highest values were found in summer. Furthermore, we observed a positive correlation between the increase in the percentage of micronuclei with nuclear abnormalities.O presente estudo teve como objetivo, determinar as variáveis leucocitárias, eritrocíticas, freqüência de micronúcleos e anomaliasnucleares nos eritrócitos do sangue periférico de Prochilodus argenteus, Pimelodus maculatus e Myleus micans de um trecho da bacia do rio São Francisco, Minas Gerais, no verão e inverno. Trombóctios, hematócrito e a serie leucocítária de P.argenteus, foi influenciado pela sazonalidade. Em P. maculatus, não ocorreram diferenças significativas para todos os leucócitos e trombócitos. Em M. micans, os valores são inéditos na literatura, apresentando VCM e número absoluto de leucócitos superior ao encontrados para outras espécies dafamília Characidae. A freqüência de micronúcleos e de anomalias nucleares nos eritrócitos, nas três espécies não apresentou diferenças sazonais e entre os pontos amostrais. No entanto, os valores mais altos foram encontrados no verão. Além disso, foi possível observar correlação positiva entre o aumento da

  16. Five essays on fiscal policy, intergenerational welfare and petroleum wealth

    Energy Technology Data Exchange (ETDEWEB)

    Thoegersen, Oe

    1994-12-01

    Motivated by current macro economic problems facing the Norwegian economy, this thesis deals with fiscal policy and the management of petroleum wealth in a small open resource economy. The thesis highlights the fact that considerable parts of the petroleum revenues are collected by the government and studies in particular the interaction between fiscal policy, uncertain petroleum revenues and welfare between generations. Essay 1 is a paper on the calculation of the Norwegian petroleum wealth and surveys economic effects of the development of the petroleum sector and the spending of the petroleum revenues. Essay 2 deals with the effects of uncertain government petroleum revenues on fiscal policy, wealth accumulation and inter generational welfare. In Essay 3 a discussion is given of the effects of oil price risk on international risk sharing. Petroleum importing and exporting countries are considered within OECD-Europe. A possible wealth consumption policy is found to have serious and long-lasting negative effects on the welfare of coming generations, as described in Essay 4. Finally, Essay 5 considers a dynamic dependent economy model extended to incorporate finite horizons of the households and structural adjustment costs in production. 121 refs., 19 figs., 10 tabs.

  17. LEARNER AUTONOMY ON ESSAY WRITING ACCURACY

    Directory of Open Access Journals (Sweden)

    Mohammad Hafidz

    2018-01-01

    Full Text Available Abstract: Learner autonomy on writing is independently teaching and learning that keeps students’ control to explore their knowledge and experiences in written language, find out and evaluate their errors based on the conceptual courses to make accurately simple essay. The aim was to know the effectiveness of the learner autonomy on writing accuracy. This quantitative research conducted in one group pretest and posttest design. The number of samples was 21 students in Bangkalan. The instrument were tests to gain students’ writing score before and after treatment. Researcher statistically analyzed the data using SPSS 23 version by running a Paired Samples Test. The result shown the means of pretes score was 66,83 and posttest score was 74,57, Paired Samples Correlations was 0,614 (strong correlation. Significance was 0,005, it means that  a (0,05 is higher than r value (0,005 with high variance of mean value (14,091. As a result, the hypothesis (H1­ was received that learner autonomy contributed effectively to learners’ in organizing own ideas (Ene, 2006 such as making a topic  map becomes some explanable sub-topics, writing down main and supporting idea, clustering some objects, editing next and learners  absolutely accumulate some selected vocabularies inappropriate topics  (Chengping W, 2008. Keyword: Learner Autonomy, Learning process, outcomes Absrak: Pembelajaran otonomi  adalah pembelajaran mandiri yang mengontrol mahasiswa untuk menyampaikan gagasan dan pengalamannya, mencatat dan mengevaluasi kesalahan yang terjadi dalam penulisan esai sederhana berdasarkan pembelajaran yang tersetruktur. Tujuan adalah untuk mengetahui efektifitas pembelajaran otonomi terhadap akurasi tulisan secara statistik. Penelitian ini dilakukan dengan menggunakan desain tes awal dan akhir. Jumlah sampel terdiri dari 21 siswa di Bangkalan. Isntrumen yang digunakan adalah tes untuk mengetahui hasil nilai mahasiswa sebelum dan sesudah melakukan

  18. APLICAÇÃO DA FERRAMENTA PDCA NA SOLUÇÃO DE PROBLEMAS DE ANOMALIAS NO PROCESSO DE OPERAÇÕES PORTUÁRIAS – ATIVIDADE PRÉ-EMBARQUE

    Directory of Open Access Journals (Sweden)

    Luísa Lemos Vilaça

    2011-06-01

    Full Text Available O objetivo deste trabalho é utilizar a técnica do PDCA em conjunto com as ferramentas da qualidade a fim de otimizar o processo de recebimento de materiais offshore no setor de pré-embarque do Porto Privado da empresa PTBR Offshore, localizado na cidade de Macaé-RJ. Tais materiais têm como destino as unidades marítimas de exploração e produção de petróleo, localizadas na Bacia de Campos e são em geral, equipamentos, ferramentas e materiais utilizados nas principais atividades da empresa, como também, mantimentos, materiais de apoio e outras cargas utilizadas e consumidas pelos trabalhadores. Todo carregamento antes de ser embarcado, é verificado e inspecionado pelos conferentes e fiscais do pré- embarque por questões de segurança, saúde e ambientais. Todo o carregamento que não é aprovado nesta etapa de inspeção e verificação, não é liberado para o embarque e retorna à sua origem para os devidos reparos da anomalia destacada. Esse processo de não-aprovação para embarque e retorno de material é chamado de desvio e será o foco deste trabalho.

  19. Essays on the frontiers of modern astrophysics and cosmology

    CERN Document Server

    Mathew, Santhosh

    2014-01-01

    This book is a collection of engaging and intriguing essays that describe an intellectual journey from the beginning to the end of universe. It is the product of an ongoing effort to know our place in the universe and share with readers the underpinnings of the magnificent cosmos where we are given a chance to exist only very briefly. The essays incorporate a group of challenging ideas that modern physics and cosmology are struggling to understand, in a unique way that incorporates mythological, religious, and philosophical perspectives. The author relies on a simple and powerful philosophy that we are part of the universe and the universe is part of us.   This wonderful collection of essays provides a journey through the current frontiers of modern astrophysics and cosmology. Its depiction of the most important unsolved mysteries about our place in the Universe is peppered with original insights and philosophical perspectives, making it an intellectual treat. – Avi Loeb, Professor, Harvard University Chai...

  20. Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.

    Directory of Open Access Journals (Sweden)

    Bai-Wei Gu

    Full Text Available Dyskeratosis congenita (DC is an inherited bone marrow failure syndrome characterized by the presence of short telomeres at presentation. Mutations in ten different genes, whose products are involved in the telomere maintenance pathway, have been shown to cause DC. The X-linked form is the most common form of the disease and is caused by mutations in the gene DKC1, encoding the protein dyskerin. Dyskerin is required for the assembly and stability of telomerase and is also involved in ribosomal RNA (rRNA processing where it converts specific uridines to pseudouridine. DC is thought to result from failure to maintain tissues, like blood, that are renewed by stem cell activity, but research into pathogenic mechanisms has been hampered by the difficulty of obtaining stem cells from patients. We reasoned that induced pluripotent stem (iPS cells from X-linked DC patients may provide information about the mechanisms involved. Here we describe the production of iPS cells from DC patients with DKC1 mutations Q31E, A353V and ΔL37. In addition we constructed "corrected" lines with a copy of the wild type dyskerin cDNA expressed from the AAVS1 safe harbor locus. We show that in iPS cells with DKC1 mutations telomere maintenance is compromised with short telomere lengths and decreased telomerase activity. The degree to which telomere lengths are affected by expression of telomerase during reprograming, or with ectopic expression of wild type dyskerin, is variable. The recurrent mutation A353V shows the most severe effect on telomere maintenance. A353V cells but not Q31E or ΔL37 cells, are refractory to correction by expression of wild type DKC1 cDNA. Because dyskerin is involved in both telomere maintenance and ribosome biogenesis it has been postulated that defective ribosome biogenesis and translation may contribute to the disease phenotype. Evidence from mouse and zebra fish models has supported the involvement of ribosome biogenesis but primary cells

  1. Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.

    Science.gov (United States)

    Gu, Bai-Wei; Apicella, Marisa; Mills, Jason; Fan, Jian-Meng; Reeves, Dara A; French, Deborah; Podsakoff, Gregory M; Bessler, Monica; Mason, Philip J

    2015-01-01

    Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized by the presence of short telomeres at presentation. Mutations in ten different genes, whose products are involved in the telomere maintenance pathway, have been shown to cause DC. The X-linked form is the most common form of the disease and is caused by mutations in the gene DKC1, encoding the protein dyskerin. Dyskerin is required for the assembly and stability of telomerase and is also involved in ribosomal RNA (rRNA) processing where it converts specific uridines to pseudouridine. DC is thought to result from failure to maintain tissues, like blood, that are renewed by stem cell activity, but research into pathogenic mechanisms has been hampered by the difficulty of obtaining stem cells from patients. We reasoned that induced pluripotent stem (iPS) cells from X-linked DC patients may provide information about the mechanisms involved. Here we describe the production of iPS cells from DC patients with DKC1 mutations Q31E, A353V and ΔL37. In addition we constructed "corrected" lines with a copy of the wild type dyskerin cDNA expressed from the AAVS1 safe harbor locus. We show that in iPS cells with DKC1 mutations telomere maintenance is compromised with short telomere lengths and decreased telomerase activity. The degree to which telomere lengths are affected by expression of telomerase during reprograming, or with ectopic expression of wild type dyskerin, is variable. The recurrent mutation A353V shows the most severe effect on telomere maintenance. A353V cells but not Q31E or ΔL37 cells, are refractory to correction by expression of wild type DKC1 cDNA. Because dyskerin is involved in both telomere maintenance and ribosome biogenesis it has been postulated that defective ribosome biogenesis and translation may contribute to the disease phenotype. Evidence from mouse and zebra fish models has supported the involvement of ribosome biogenesis but primary cells from human

  2. Essays on the economics of decarbonization and renewable energy support

    International Nuclear Information System (INIS)

    Jaegemann, Cosima Claudia

    2014-01-01

    The thesis consists of five essays investigating various aspects associated with the decarbonization of Europe's power sector and the politically incentivized expansion of renewable energy generation. The first essay analyzes the economic implications of alternative decarbonization pathways and policy instruments for Europe's power sector up to 2050 and illustrates the importance of ensuring competition between all low-carbon technologies in order to limit the costs of decarbonization. The second essay analyzes the economic inefficiency associated with the concept of grid parity for the case of photovoltaic (PV). In order to both enhance overall welfare and avoid redistributional effects, the indirect financial incentive for in-house PV electricity consumption should be abolished. The third essay discusses the system price effect of wind and solar power generation and illustrates that the decrease in the marginal value of wind and solar power (as a consequence of increased penetration) is already highly relevant for both wind and solar power generation in Germany. The fourth essay adds to the ongoing debate surrounding the cost-efficient achievement of politically implemented renewable energy targets. Renewable energy support schemes that fail to incentivize investors to account for differences in the marginal value of wind and solar power generation are associated with excess costs as they prevent the equalization of net marginal costs across technologies and regions. The fifth essay analyzes the economic value of storage as a function of the overall generation mix and illustrates the economic inefficiency arising from feed-in tariff systems for the special case of thermal energy storage units in concentrating solar power plants.

  3. Essays on the economics of decarbonization and renewable energy support

    Energy Technology Data Exchange (ETDEWEB)

    Jaegemann, Cosima Claudia

    2014-06-05

    The thesis consists of five essays investigating various aspects associated with the decarbonization of Europe's power sector and the politically incentivized expansion of renewable energy generation. The first essay analyzes the economic implications of alternative decarbonization pathways and policy instruments for Europe's power sector up to 2050 and illustrates the importance of ensuring competition between all low-carbon technologies in order to limit the costs of decarbonization. The second essay analyzes the economic inefficiency associated with the concept of grid parity for the case of photovoltaic (PV). In order to both enhance overall welfare and avoid redistributional effects, the indirect financial incentive for in-house PV electricity consumption should be abolished. The third essay discusses the system price effect of wind and solar power generation and illustrates that the decrease in the marginal value of wind and solar power (as a consequence of increased penetration) is already highly relevant for both wind and solar power generation in Germany. The fourth essay adds to the ongoing debate surrounding the cost-efficient achievement of politically implemented renewable energy targets. Renewable energy support schemes that fail to incentivize investors to account for differences in the marginal value of wind and solar power generation are associated with excess costs as they prevent the equalization of net marginal costs across technologies and regions. The fifth essay analyzes the economic value of storage as a function of the overall generation mix and illustrates the economic inefficiency arising from feed-in tariff systems for the special case of thermal energy storage units in concentrating solar power plants.

  4. Cosmopolitanism and peace in Kant's essay on 'Perpetual Peace'

    DEFF Research Database (Denmark)

    Huggler, Jørgen

    2010-01-01

    Immanuel Kant's essay on Perpetual Peace (1795/96) contains a rejection of the idea of a world government (earlier advocated by Kant himself). In connexion with a substantial argument for cosmopolitan rights based on the human body and its need for a space on the surface of the Earth, Kant presents...... the most rigorous philosophical formulation ever given of the limitations of the cosmopolitan law. In this contribution, Kant's essay is analysed and the reasons he gives for these restrictions discussed in relation to his main focus: to project a realistic path to perpetual peace....

  5. Proposing a Wiki-Based Technique for Collaborative Essay Writing

    Directory of Open Access Journals (Sweden)

    Mabel Ortiz Navarrete

    2014-10-01

    Full Text Available This paper aims at proposing a technique for students learning English as a foreign language when they collaboratively write an argumentative essay in a wiki environment. A wiki environment and collaborative work play an important role within the academic writing task. Nevertheless, an appropriate and systematic work assignment is required in order to make use of both. In this paper the proposed technique when writing a collaborative essay mainly attempts to provide the most effective way to enhance equal participation among group members by taking as a base computer mediated collaboration. Within this context, the students’ role is clearly defined and individual and collaborative tasks are explained.

  6. Space, Time, Matter, and Form Essays on Aristotle's Physics

    CERN Document Server

    Bostock, David

    2006-01-01

    Space, Time, Matter, and Form collects ten of David Bostock's essays on themes from Aristotle's Physics, four of them published here for the first time. The first five papers look at issues raised in the first two books of the Physics, centred on notions of matter and form, and the idea of substance as what persists through change. They also range over other of Aristotle's scientific works, such as his biology and psychology and the account of change in his De Generatione et Corruptione. The volume's remaining essays examine themes in later books of the Physics, including infinity, place, time

  7. Essays in general relativity a Festschrift for Abraham Taub

    CERN Document Server

    Tipler, Frank J

    1981-01-01

    Essays in General Relativity: A Festschrift for Abraham Taub is collection of essays to honor Professor Abraham H. Taub on the occasion of his retirement from the mathematics faculty of the University of California at Berkeley. Relativistic hydrodynamics has always been a subject dear to Taub's heart. In fact, many basic results on special relativistic fluid flows are due to him, and he has been a major contributor to the study of fluid flows near shocks. The book contains 16 chapters and begins with a discussion of a geometrical approach to general relativity. This is followed by separate cha

  8. Essays on Energy Technology Innovation Policy

    Science.gov (United States)

    Chan, Gabriel Angelo Sherak

    .S. Department of Energy's National Laboratories, and provide the first quantitative evidence that technology transfer agreements at the Labs lead to greatly increased rates of innovation spillovers. This chapter also makes a key methodological contribution by introducing a technique to utilize automated text analysis in an empirical matching design that is broadly applicable to other types of social science studies. This work has important implications for how policies should be designed to maximize the social benefits of the $125 billion in annual federal funding allocated to research and development and the extent to which private firms can benefit from technology partnerships with the government. The final chapter of this dissertation explores the effectiveness of international policy to facilitate the deployment of low-emitting energy technologies in developing countries. Together with Joern Huenteler, I examine wind energy deployment in China supported through international climate finance flows under the Kyoto Protocol's Clean Development Mechanism. Utilizing a project-level financial model of wind energy projects parameterized with high-resolution observations of Chinese wind speeds, we find that the environmental benefits of projects financed under the Clean Development Mechanism are substantially lower than reported, as many Chinese wind projects would have been built without the Mechanism's support, and thus do not represent additional clean energy generation. Together, the essays in this dissertation suggest several limitations of energy technology innovation policy and areas for reform. Public funds for energy research and development could be made more effective if decision making approaches were better grounded in available technical expertise and developed in framework that captures the important interactions of technologies in a research and development portfolio. The first chapter of this dissertation suggests a politically feasible path towards this type of

  9. EDITORIAL: George W Series Memorial Essays

    Science.gov (United States)

    Dodd, J. N.

    1997-01-01

    tuneable lasers, generally with the emphasis on understanding the underlying physics rather than accumulating data. He had a highly original mind, which showed both in his choice of research topics and in his method of approach. He did not follow fashion; his instinct for an interesting problem was at odds with the modem policy of direct funding and the identification of "growth areas". His applications for research grants were often unsuccessful, despite his high international standing and integrity. He was never interested in building up a large research team, and had comparatively few research students, but his enthusiasm and commitment to the quality of his science attracted a succession of overseas visitors to his laboratory. Following my own year at the Clarendon, and some subsequent visits both to Oxford and to Reading, there was a continuing strong association between the Clarendon and Otago Physics that continues until today. George Series was the William Evans Visiting Professor to Otago University in 1972. He never lost his interest in the fundamentals of physics inspired by his first researches into the structure of the hydrogen atom; he wrote on the Rydberg constant, the physics of spontaneous emission, and on the fine-structure constant α = e2/hc. He donated a garden seat to St Edmund Hall (Oxford), of which he was a Fellow. On it he placed a plaque* in recognition of the ubiquitous nature of this constant; it almost had magical significance for him. He served physics in many ways outside research. He was for a number of years the Editor of the European Journal of Physics and was also Editor of the Journal of Physics B: Atomic and Molecular Physics, He was also on the Editorial Board of a number of journals. He was elected to Fellowship of a number of physics societies. The Editorial Board of these Memorial Essays dedicate them to George's memory, and to his wife Annette and his family.

  10. General And Specific Features In Realizing An Essay In English Language – A Case Study Of Essay On Economic Themes

    Directory of Open Access Journals (Sweden)

    Daliana Ecaterina TASCOVICI

    2016-04-01

    Full Text Available The present paper wants to be a systematic and not only a theoretical approach on essays. This type of writing knows several points of view connecting its form, content, specific features and types, rules to be observed in its writing, structures or styles. As we know, it implies freedom of composition, originality, associations of surprising images and propensity for aphorism. We try to frame all its specifications within the economic essay, as economics is a field of exact utterance, where the speaker cannot play with the words and their meaning.

  11. Classification of Swedish Learner Essays by CEFR Levels

    Science.gov (United States)

    Volodina, Elena; Pilán, Ildikó; Alfter, David

    2016-01-01

    The paper describes initial efforts on creating a system for the automatic assessment of Swedish second language (L2) learner essays from two points of view: holistic evaluation of the reached level according to the Common European Framework of Reference (CEFR), and the lexical analysis of texts for receptive and productive vocabulary per CEFR…

  12. Essays on the economics of British Columbian timber policy

    NARCIS (Netherlands)

    Niquidet, Kurt

    2007-01-01

    This thesis examines the process of institutional change in British Columbia’s timber sector. It is composed of a series of essays which highlight the underlying political and economic factors that have shaped past and current reforms. Taking center stage in the analysis, are the resource rents

  13. Mass Media and the National Experience; Essays in Communications History.

    Science.gov (United States)

    Farrar, Ronald T., Ed.; Stevens, John D., Ed.

    In 11 different essays, journalism historians reflect on the present state of their art and suggest ways and means of doing the important work that lies ahead. Areas of productive research suggested include freedom of expression, politics and economics, technology regionalism, Black journalism, the journalist as social critic, photographic…

  14. Cosmopolitanism and Peace in Kant's Essay on "Perpetual Peace"

    Science.gov (United States)

    Huggler, Jorgen

    2010-01-01

    Immanuel Kant's essay on Perpetual Peace (1795/96) contains a rejection of the idea of a world government (earlier advocated by Kant himself). In connexion with a substantial argument for cosmopolitan rights based on the human body and its need for a space on the surface of the Earth, Kant presents the most rigorous philosophical formulation ever…

  15. Entrepreneurship and innovation. Essays in honour of Wim During

    NARCIS (Netherlands)

    van der Sijde, Peter; Ridder, Annemarie; Groen, Arend J.

    2004-01-01

    Wim During started his work at the University of Twente in 1973. During his academic career, he elaborated two main themes: (high tech) entrepreneurship and high-tech small firms. The essays in this book -published on the occasion of his retirement as professor of Innovative Entrepreneurship at the

  16. Sources of Social Control in School: A Speculative Essay.

    Science.gov (United States)

    Schlechty, Phillip C.; Burke, William I.

    1980-01-01

    This essay attempts to demonstrate that age segregation and subject matter specialization are two important supports of the authority of teachers and the school's ability to control students. Therefore, efforts to change these organizational patterns without considering alternative means of establishing control are doomed to failure. (Author/SJL)

  17. Should God Get Tenure? Essays on Religion and Higher Education.

    Science.gov (United States)

    Gill, David W., Ed.

    Essays on the role of religion in higher education include: "Should God Get Tenure?" (David W. Gill); "On Being a Professor: The Case of Socrates" (Bruce R. Reichenbach); "Academic Excellence: Cliche or Humanizing Vision?" (Merold Westphal); "Religion, Science, and the Humanities in the Liberal Arts Curriculum" (H. Newton Maloney); "Tolstoy and…

  18. Rhetorical, Metacognitive, and Cognitive Strategies in Teacher Candidates' Essay Writing

    Science.gov (United States)

    Diaz Larenas, Claudio; Ramos Leiva, Lucía; Ortiz Navarrete, Mabel

    2017-01-01

    This paper reports on a study about the rhetoric, metacognitive, and cognitive strategies pre-service teachers use before and after a process-based writing intervention when completing an argumentative essay. The data were collected through two think-aloud protocols while 21 Chilean English as a foreign language pre-service teachers completed an…

  19. Certainty Judgements and the Status of Propositions in Undergraduate Essays

    Science.gov (United States)

    Siew Mei, Wu

    2013-01-01

    This paper explores the expression of certainty in a set of high- and low-rated Geography argumentative essays. Using one aspect of Hunston's (1989, 2000) concept of the evaluation of status, the paper compares the statement types used to construe the writer's expression of certainty in the construction of arguments. Drawing on the framework,…

  20. Improving Undergraduates' Argumentative Group Essay Writing through Self-Assessment

    Science.gov (United States)

    Fung, Yong Mei; Mei, Hooi Chee

    2015-01-01

    When writing an argumentative essay, writers develop and evaluate arguments to embody, initiate, or simulate various kinds of interpersonal and textual interaction for reader consideration (Wu & Allison, 2003). This is quite challenging for English as a second language (ESL) learners. To improve the quality of their writing, students need to…

  1. "Argument!" Helping Students Understand What Essay Writing Is About

    Science.gov (United States)

    Wingate, Ursula

    2012-01-01

    Argumentation is a key requirement of the essay, which is the most common genre that students have to write. However, how argumentation is realised in disciplinary writing is often poorly understood by academic tutors, and therefore not adequately taught to students. This paper presents research into undergraduate students' concepts of argument…

  2. Gaia and the Daysies' Revolution: an Essay about Lovelockian Theory

    Directory of Open Access Journals (Sweden)

    Andrés Betancourt Morales

    2000-07-01

    Full Text Available This essay tries to stand, from an explanatory and argumentative point of view, some aspects of the James Lovelock's Gaia's theory, such as its main ideas and influence, having in count the difficulties it had to be accepted and the consequences for the Biology's development of Gaia's theory in general and of the Daysyworld model in particular.

  3. Accounting Issues: An Essay Series Part V--Intangible Assets

    Science.gov (United States)

    Laux, Judy

    2008-01-01

    This article represents the fifth in a series of theoretical essays intended to supplement the introductory financial accounting course and investigates the accounting treatment and related conceptual connections for intangibles. In addition, intangibles present unique accounting issues, conceptual challenges, and measurement dilemmas not found…

  4. Dostoevsky: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Wellek, Rene, Ed.

    One of a series of works aimed at presenting contemporary opinion on major authors, this collection includes essays by Rene Wellek, Philip Rahv, Murray Krieger, Irving Howe, Eliseo Vivas, D. H. Lawrence, Sigmund Freud, Dmitri Chizhevsky, V. V. Zenkovsky, Georg Lukacs, and Derek Traversi--all dealing with the biography and literary work of…

  5. The Sensible and Insensible Body: A Visual Essay

    Directory of Open Access Journals (Sweden)

    Joanna Bourke

    2012-12-01

    Full Text Available Translating pain into tangible images brings it into the public consciousness, raising the spectre of bodily suffering as virtually intrinsic to the human condition. Beginning with Descartes, who famously advanced mind-body theories in the late seventeenth century, this essay explores the effects of his influence together with shifting attitudes towards pain and its role over the long nineteenth century.

  6. The Psychology of Reading Instruction (A Collection of Essays).

    Science.gov (United States)

    Ediger, Marlow

    Focusing on various areas of concern to classroom teachers, this collection contains the following essays: (1) "Herbart versus Froebel on Teaching Pupils"; (2) "The Integrated Reading Curriculum"; (3) "Motivation and the Learner in Reading"; (4) "Issues in the Reading Curriculum"; (5) "Inservice Education and the Curriculum"; (6) "Textbooks and…

  7. Mucinous carcinoma of the breast: iconographic essay with histopathological correlation

    Directory of Open Access Journals (Sweden)

    Gustavo Nunes Medina Coeli

    2013-07-01

    Full Text Available The present essay is aimed at describing the most characteristic imaging findings of mucinous carcinoma of the breast, with emphasis on the patterns related to better prognosis. The authors selected cases of mucinous carcinoma of the breast whose images were available, highlighting the imaging findings suggestive of this subtype of breast cancer, either at mammography, ultrasonography or magnetic resonance imaging.

  8. Towards a Realist Sociology of Education: A Polyphonic Review Essay

    Science.gov (United States)

    Grenfell, Michael; Hood, Susan; Barrett, Brian D.; Schubert, Dan

    2017-01-01

    This review essay evaluates Karl Maton's "Knowledge and Knowers: Towards a Realist Sociology of Education" as a recent examination of the sociological causes and effects of education in the tradition of the French social theorist Pierre Bourdieu and the British educational sociologist Basil Bernstein. Maton's book synthesizes the…

  9. Three Essays on Bureaucracy at American Research Universities

    Science.gov (United States)

    Taggart, Gabel

    2017-01-01

    The three essays in this dissertation each examine how aspects of contemporary administrative structure within American research universities affect faculty outcomes. Specific aspects of administrative structure tested in this dissertation include the introduction of new administrative roles, administrative intensity (i.e., relative size of…

  10. The Education of a Teacher. Essays on American Culture.

    Science.gov (United States)

    Wolf, Howard

    Written in the immediacy of the Vietnam period and its aftermath, these essays record, from the perspective of a college professor, the dramatic shifts of students from the active, even violent, style of protests for social justice of the sixties to the self-interested "protest of style" of the seventies, to the insecurity and career orientation…

  11. MDCT imaging of post interventional liver: a pictorial essay

    International Nuclear Information System (INIS)

    Romano, Stefania; Tortora, Giovanni; Scaglione, Mariano; Lassandro, Francesco; Guidi, Guido; Grassi, Roberto; Romano, Luigia

    2005-01-01

    In this pictorial essay, we consider the post operative MDCT findings after liver resection, transplantation, surgical managed major trauma and radiofrequency ablation of focal lesions. Common complications such as fluid collections, hemorrhage, biloma, vascular disease, hematoma, abscesses will be also considered

  12. Essays on Pricing of Information Goods and Services

    Science.gov (United States)

    Lahiri, Atanu

    2010-01-01

    This dissertation consists of three essays that examine, in three specific contexts, issues related to pricing of information goods and services. As the ability to measure technology resource usage gets easier with increased connectivity, the question whether a technology resource should be priced by the amount of the resource used or by the…

  13. Yeats: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Unterecker, John, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by John Unterecker, W. H. Auden, High Kenner, Giogio Melchiori, Frank Kermode, W. Y. Tindall, T. S. Eliot, R. P. Blackmur, Alex Zwerdling, Curtis Bradford, D. J. Gordon, Ian Fletcher, A. G. Stock, Allen Tate, and Richard…

  14. Homer: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Steiner, George, Ed.; Fagles, Robert, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by George Steiner, Leo Tolstoy, Ezra Pound, Erich Auerbach, Edwin Muir, Cedric H. Whitman, Albert B. Lord, W. H. Auden, Ernst Bloch, Georg Lukacs, C. Day Lewis, Gabriel Germain, Franz Kafka, Rachel Bespaloff, Robert…

  15. Hardy: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Guerard, Albert J., Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Albert Guerard, Donald Davidson, Morton Dauwen Zabel, D. H. Lawrence, John Hollowan, Dorothy Van Ghent, John Paterson, A. Alvarez, Delmore Schwartz, W. H. Auden, David Perkins, and Samuel Hynes--all dealing with the…

  16. Evaluating the assessment of essay type questions in the basic ...

    African Journals Online (AJOL)

    Methodology: We examined the merits and demerits of the closed and open systems of assessment of essay type questions and viva voce in professional exams in the Basic Medical Sciences together with the challenges of present day Medical Education. Result: The result showed that the closed system of marking in its ...

  17. Admitted or Denied: Multilingual Writers Negotiate Admissions Essays

    Science.gov (United States)

    Wight, Shauna

    2017-01-01

    This article presents data from a collection of yearlong case studies on resident multilingual writers' college admissions essays. The focal student in this piece revealed the challenges that such writers face in presenting themselves to college admissions officers. Exploring these cultural and linguistic conflicts, this analysis uses Goffman's…

  18. Effectiveness of Student Admission Essays in Identifying Attrition.

    Science.gov (United States)

    Sadler, Judith

    2003-01-01

    From a longitudinal sample of nursing students, 193 completers and 43 noncompleters were compared, revealing significant differences in the groups' mean scores on admission essays but not admission grade point averages. Content analysis revealed how completers had internalized the role of nurse. (Contains 12 references.) (SK)

  19. Imaging evaluation of middle ear cholesteatoma: iconographic essay

    Energy Technology Data Exchange (ETDEWEB)

    Avila, Ana Flavia Assis de; Aburjeli, Bruna de Oliveira Melim; Moreira, Wanderval; Motta, Emilia Guerra Pinto Coelho; Ribeiro, Marcelo Almeida; Diniz, Renata Lopes Furletti Caldeira, E-mail: fauassis@hotmail.com [Hospital Mater Dei, Belo Horizonte, MG (Brazil)

    2013-06-15

    Middle ear cholesteatoma is a relevant and relatively common disease that may have severe consequences. In the present pictorial essay, the authors have selected illustrative examples of multislice computed tomography and magnetic resonance imaging depicting the main presentations of cholesteatomas, and describing their characteristics, locations, and major complications. (author)

  20. Profiling Learners' Achievement Goals when Completing Academic Essays

    Science.gov (United States)

    Ng, Chi-Hung Clarence

    2009-01-01

    This study explored adult learners' goal profiles in relation to the completion of a compulsory academic essay. Based on learners' scores on items assessing mastery, performance-approach, and work-avoidance goals, cluster analyses produced three distinct categories of learners: performance-focused, work-avoidant, and multiple-goal learners. These…

  1. Source-Based Tasks in Writing Independent and Integrated Essays

    Directory of Open Access Journals (Sweden)

    Javad Gholami

    2017-07-01

    Full Text Available Integrated writing tasks have gained considerable attention in ESL and EFL writing assessment and are frequently needed and used in academic settings and daily life. However, they are very rarely practiced and promoted in writing classes. This paper explored the effects of source-based writing practice on EFL learners’ composing abilities and investigated the probable differences between those tasks and independent writing ones in improving Iranian EFL learners’ essay writing abilities. To this end, a quasi-experimental design was implemented to gauge EFL learners’ writing improvements using a pretest-posttest layout. Twenty female learners taking a TOEFL iBT preparation course were randomly divided into an only-writing group with just independent writing instruction and essay practice, and a hybrid-writing-approach group receiving instruction and practice on independent writing plus source-based essay writing for ten sessions. Based on the findings, the participants with hybrid writing practice outperformed their counterparts in integrated essay tests. Their superior performance was not observed in the case of traditional independent writing tasks. The present study calls for incorporating more source-based writing tasks in writing courses.

  2. Essays in competition with product differentiation and bargaining in markets

    NARCIS (Netherlands)

    Bouckaert, J.M.C.

    1996-01-01

    The fourth essay uses bargaining theory and compares the outcome of a negotiation in two differently organized markets. In the first market, sellers simultaneously offer their good or service for sale. In the second market, sellers queue and offer their good or service sequentially for sale.

  3. Hemingway; A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Weeks, Robert P., Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Lillian Ross, Malcolm Crowley, E.M. Halliday, Harry Levin, Leslie Fiedler, D.H. Lawrence, Philip Young, Sean O'Faolain, Cleanth Brooks and Robert Penn Warren, Carlos Baker, Mark Spilka, Ray B. West, Jr., Nemi D'Agostino,…

  4. Essays on Port, Container, and Bulk Chemical Logistics Optimization

    NARCIS (Netherlands)

    E. van Asperen (Eelco)

    2009-01-01

    textabstractThe essays in this thesis are concerned with two main themes in port logistics. The first theme is the coordination of transport arrivals with the distribution processes and the use of storage facilities. We study this for both containerized and bulk chemical transport. The second theme

  5. Anatomy of the ankle ligaments: a pictorial essay

    NARCIS (Netherlands)

    Golanó, Pau; Vega, Jordi; de Leeuw, Peter A. J.; Malagelada, Francesc; Manzanares, M. Cristina; Götzens, Víctor; van Dijk, C. Niek

    2010-01-01

    Understanding the anatomy of the ankle ligaments is important for correct diagnosis and treatment. Ankle ligament injury is the most frequent cause of acute ankle pain. Chronic ankle pain often finds its cause in laxity of one of the ankle ligaments. In this pictorial essay, the ligaments around the

  6. Anatomy of the ankle ligaments: a pictorial essay

    NARCIS (Netherlands)

    Golanó, Pau; Vega, Jordi; de Leeuw, Peter A. J.; Malagelada, Francesc; Manzanares, M. Cristina; Götzens, Víctor; van Dijk, C. Niek

    2016-01-01

    Understanding the anatomy of the ankle ligaments is important for correct diagnosis and treatment. Ankle ligament injury is the most frequent cause of acute ankle pain. Chronic ankle pain often finds its cause in laxity of one of the ankle ligaments. In this pictorial essay, the ligaments around the

  7. Three Epiphanic Fragments: Education and the Essay in Memory

    Science.gov (United States)

    Aldridge, David

    2014-01-01

    Pádraig Hogan has argued for a powerful conception of education as epiphany that is illuminated by the work of Heidegger and Joyce. But what are we to make of Stephen Dedalus' intention (pretension?) to "Remember your epiphanies"? Developing the phenomenological Erinnerungsversuch or "essay in memory" of David Farrell…

  8. Antropologie tussen wetenschap en kunst : Essays over Clifford Geertz

    NARCIS (Netherlands)

    Kuiper, Yme; Bakker, Jan Willem; Miedema, Jelle

    1987-01-01

    Clifford Geertz (*1926) is one of the most influential anthropologists of his generation. His most famous monographs and collection of essays are The Religion of Java, Agricultural Involution, Islam Observed, The Interpretation of Cultures, Local Knowledge, Negara: The Balinese Theatre State in

  9. Review Essay: Recent Scholarship from the Buryat Mongols of Siberia

    Directory of Open Access Journals (Sweden)

    Robert W. Montgomery

    2012-11-01

    Full Text Available Review essay on the edited volume Etnicheskaia istoriia i kul’turno-bytovye traditsii narodov baikal’skogo regiona. [The Ethnic History and the Traditions of Culture and Daily Life of the Peoples of the Baikal Region] Ed. M. N. Baldano, O. V. Buraeva and D. D. Nimaev (Ulan-Ude, 2010

  10. Automated Guidance for Thermodynamics Essays: Critiquing versus Revisiting

    Science.gov (United States)

    Donnelly, Dermot F.; Vitale, Jonathan M.; Linn, Marcia C.

    2015-01-01

    Middle school students struggle to explain thermodynamics concepts. In this study, to help students succeed, we use a natural language processing program to analyze their essays explaining the aspects of thermodynamics and provide guidance based on the automated score. The 346 sixth-grade students were assigned to either the critique condition…

  11. Ideals and realities selected essays of Abdus Salam

    CERN Document Server

    Salam, Abdus; Lai, CH

    1989-01-01

    The latest edition of "Ideals and Realities" includes some of the most recent talks given by Professor Abdus Salam. They replace a few essays which were published in the second edition. An attempt has also been made to update some of the figures rendered absolete with the passage of time.

  12. Calculation of uncertainties in influence quantities in biological essays

    Directory of Open Access Journals (Sweden)

    Pierre Morel

    2006-01-01

    Full Text Available Due to the need of showing the reliability of results from biological essays, such as in health and environmental areas, laboratories have been implementing quality systems, particularly ABNT NBR ISO/IEC 17025 (ABNT, 2001, which include as one of the requirements, the calculation of uncertainty in essays results. It is of common knowledge that estimating uncertainty in essays using organisms, such as animal and vegetal species, is difficult, preventing from meeting that requirement in the standard. The paper shows the calculation of uncertainties in influences quantities in these essays as a tool to allow validating the measuring process, by using the essays performed by Rhodia Environmental Impact Analysis Laboratory and IPEN Ecotoxicology Laboratory as examples.Devido à necessidade de demonstrar a confiabilidade dos resultados de ensaios biológicos como, por exemplo, nas áreas de saúde e ambiental, laboratórios vêm implementando sistemas da qualidade, em especial a ABNT NBR ISO/IEC 17025 (ABNT, 2001 que inclui como um dos requisitos o cálculo da incerteza dos resultados dos ensaios. É reconhecidamente difícil de estimar a incerteza de ensaios que utilizam organismos, como com espécies animais e vegetais o que impede, consequentemente, o atendimento deste requisito da norma. O trabalho apresenta o cálculo de incerteza das grandezas de influências nestes ensaios como uma ferramenta que permite validar o processo de medição, utilizando como exemplos aqueles realizados pelos Laboratórios de Análise de Impacto Ambiental da Rhodia e de Ecologia e Ecotoxicologia do IPEN.

  13. Essays on the role of accounting in acquisition decision-making

    OpenAIRE

    Puhakka, Hannu

    2017-01-01

    This dissertation investigates the role of accounting in acquisition decision-making via three essays. First essay examines the influence of accounting on trust development during the acquisition negotiation process. Essay 2 explores the interplay of formal and informal pre-decision control mechanisms and seeks to provide new insights on the interplay of various pre-decision control mechanisms at different stages of the acquisition decision-making process. Third essay seeks to specify how acc...

  14. Estratégia para o tratamento cirúrgico das anomalias da conexão ventrículo-arterial com comunicação interventricular: surgical strategy Repair of anomalies of ventriculo-arterial connections

    Directory of Open Access Journals (Sweden)

    José Caliani

    1989-08-01

    Full Text Available Designamos anomalias da conexão ventrículo-arterial toda a conexão que difere daquela de um coração normal. Dentro desta abordagem, não utilizamos os termos ventrículo direito ou esquerdo com dupla via de saída, Taussig-Bing e transposição das grandes artérias, quando estes estão associados a uma comunicação interventricular. Nestas anomalias, o objetivo da correção é o de conectar o ventrículo esquerdo com a aorta e o ventrículo direito com a artéria pulmonar. A estratégia que escolhemos é baseada na hipótese de que a correção mais simples é aquela que não exige a utilização de um tubo profético, a transferência de coronárias, ou a septação complexa da cavidade ventricular. Baseados na experiência de 162 correções para as anomalias da conexão ventrículo-arterial, em uma série de 197 pacientes, utilizamos três tipos de correção anatômica: a correção intraventricular (tunelização ventrículo esquerdo-aorta em 35 pacientes, o REV (tunelização ventrículo esquerdo-aorta associada a translocação do tronco pulmonar sobre o ventrículo direito em 78 pacientes, e a operação de Jatene associada ao fechamento da comunicação interventricular em 49 pacientes. O tipo de correção ideal é a correção intraventricular, na qual a simples tunelização ventrículo esquerdo-aorta estabelece uma conexão ventrículo-arterial normal. Quando a correção intraventricular não é possível, nós indicamos o REV em presença de estenose pulmonar e a operação de Jatene na ausência desta. A questão principal é saber quando uma correção intraventricular é realizável. A realização desta é função da distância entre a valva tricúspide e a valva pulmonar. Se esta distância é suficientemente grande (igual ou superior ao diâmetro do orifício aórtico, o túnel intraventricular é realizável; se não, outra modalidade de correção é indicada. Nossa experiência atual sugere que a exploração pr

  15. Discussion of David Thissen's Bad Questions: An Essay Involving Item Response Theory

    Science.gov (United States)

    Wainer, Howard

    2016-01-01

    The usual role of a discussant is to clarify and correct the paper being discussed, but in this case, the author, Howard Wainer, generally agrees with everything David Thissen says in his essay, "Bad Questions: An Essay Involving Item Response Theory." This essay expands on David Thissen's statement that there are typically two principal…

  16. Discourse Connector Usage in Argumentative Essays by American and Thai University Students

    Science.gov (United States)

    Jangarun, Kamolphan; Luksaneeyanawin, Sudaporn

    2016-01-01

    This study investigated the similarities and differences in the use of discourse connectors (DCs) in argumentative essays of American undergraduate students (AMs), Thai with high-English exposure (THHs) and Thai with low-English exposure (THLs). The data of these three groups were collected from 60 essays; 20 essays were from the corpus of…

  17. Rethinking the Ph.D. in English. Carnegie Essays on the Doctorate: English.

    Science.gov (United States)

    Lunsford, Andrea Abernethy

    The Carnegie Foundation commissioned a series of essays as part of the Carnegie Initiative on the Doctorate (CID). The essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. The essay explores the Ph.D. in English and suggests changes the author would make in…

  18. Essays on pricing electricity and electricity derivatives in deregulated markets

    Science.gov (United States)

    Popova, Julia

    2008-10-01

    This dissertation is composed of four essays on the behavior of wholesale electricity prices and their derivatives. The first essay provides an empirical model that takes into account the spatial features of a transmission network on the electricity market. The spatial structure of the transmission grid plays a key role in determining electricity prices, but it has not been incorporated into previous empirical models. The econometric model in this essay incorporates a simple representation of the transmission system into a spatial panel data model of electricity prices, and also accounts for the effect of dynamic transmission system constraints on electricity market integration. Empirical results using PJM data confirm the existence of spatial patterns in electricity prices and show that spatial correlation diminishes as transmission lines become more congested. The second essay develops and empirically tests a model of the influence of natural gas storage inventories on the electricity forward premium. I link a model of the effect of gas storage constraints on the higher moments of the distribution of electricity prices to a model of the effect of those moments on the forward premium. Empirical results using PJM data support the model's predictions that gas storage inventories sharply reduce the electricity forward premium when demand for electricity is high and space-heating demand for gas is low. The third essay examines the efficiency of PJM electricity markets. A market is efficient if prices reflect all relevant information, so that prices follow a random walk. The hypothesis of random walk is examined using empirical tests, including the Portmanteau, Augmented Dickey-Fuller, KPSS, and multiple variance ratio tests. The results are mixed though evidence of some level of market efficiency is found. The last essay investigates the possibility that previous researchers have drawn spurious conclusions based on classical unit root tests incorrectly applied to

  19. Three Essays Examining Household Energy Demand and Behavior

    Science.gov (United States)

    Murray, Anthony G.

    This dissertation consists of three essays examining household energy decisions and behavior. The first essay examines the adoption of energy efficient Energy Star home appliances by U.S. households. Program effectiveness requires that consumers be aware of the labeling scheme and also change their purchase decisions based on label information. The first essay examines the factors associated with consumer awareness of the Energy Star label of recently purchased major appliances and the factors associated with the choice of Energy Star labeled appliances. The findings suggest that eliminating identified gaps in Energy Star appliance adoption would result in house electricity cost savings of $164 million per year and associated carbon emission reductions of about 1.1 million metric tons per year. The second essay evaluates household energy security and the effectiveness of the Low-Income Home Energy Assistance Program (LIHEAP), the single largest energy assistance program available to poor households within the United States. Energy security is conceptually akin to the well-known concept of food security. Rasch models and household responses to energy security questions in the 2005 Residential Energy Consumption Survey are used to generate an energy insecurity index that is consistent with those found in the food insecurity literature. Participating in LIHEAP is found to significantly reduce household energy insecurity score in the index. Further, simulations show that the elimination of the energy assistance safety net currently available to households increases the number of energy insecure house- holds by over 16 percent. The third essay develops a five equation demand system to estimate household own-price, cross-price and income elasticities between electricity, natural gas, food at home, food away from home, and non-durable commodity groups. Household cross-price elasticities between energy and food commodities are of particular importance. Energy price shocks

  20. Essays on alternative energy policies affecting the US transportation sector

    Science.gov (United States)

    O'Rear, Eric G.

    This dissertation encompasses three essays evaluating the impacts of different policies targeting the greenhouse gas (GHG) emissions, fuel demands, etc. of the transportation sector. Though there are some similarities across the three chapters, each essay stands alone as an independent work. The 2010 US EPA MARKAL model is used in each essay to evaluate policy effects. Essay 1 focuses on the recent increases in Corporate Average Fuel Economy (CAFE) standards, and the implications of a "rebound effect." These increases are compared to a carbon tax generating similar reductions in system-wide emissions. As anticipated, the largest reductions in fuel use by light-duty vehicles (LDV) and emissions are achieved under CAFE. Consideration of the rebound effect does little to distort CAFE benefits. Our work validates many economists' belief that a carbon tax is a more efficient approach. However, because the tax takes advantage of cheaper abatement opportunities in other sectors, reductions in transportation emissions will be much lower than what we observe with CAFE. Essay 2 compares CAFE increases with what some economists suggest would be a much more "efficient" alternative -- a system-wide oil tax internalizing some environmental externalities. Because oil taxes are likely to be implemented in addition to CAFE standards, we consider a combined policy case reflecting this. Our supplementary analysis approximates the appropriate tax rates to produce similar reductions in oil demands as CAFE (CAFE-equivalent tax rates). We discover that taxes result in greater and more cost-effective reductions in system-wide emissions and net oil imports than CAFE. The current fuel tax system is compared to three versions of a national vehicle miles traveled (VMT) tax charged to all LDVs in Essay 3. VMT taxes directly charge motorists for each mile driven and help to correct the problem of eroding tax revenues given the failure of today's fuel taxes to adjust with inflation. Results

  1. Photo Essay: Pictures for Our “Honorable American Friends”

    Directory of Open Access Journals (Sweden)

    Samuel Hideo Yamashita

    2013-03-01

    Full Text Available An American minister’s outrage over a celebration of the dropping of the atomic bombs on Japan led to a generous gift of school supplies for students at a primary school in Hiroshima City. In gratitude, students at this school sent dozens of drawings and paintings to the minister’s church. This exchange was inspired by the minister’s Unitarian faith and moral decency and realized through the generosity of his parishioners. But the Japanese children’s artwork can be read in several other ways that greatly complicate the story and implicate Cold War narratives of victory and defeat as well as powerful memories of the destruction, death, and suffering caused by the war. This essay accompanies the “Hiroshima Children’s Drawings” photo essay featured in the March 2013 issue of Cross-Currents: East Asian History and Culture Review...

  2. Tourism in a World of Risks (Essay Review

    Directory of Open Access Journals (Sweden)

    Maximiliano E. KORSTANJE

    2016-06-01

    Full Text Available Though tourism combines curiosity with security, over the recent decades, we are facing an inflation of risks that caused big problems for policy makers and officials interested in promoting tourism in their respective nations. As a result of this, one might speculate that the future of industry is uncertain. This essay review explores the already existent literature in risk perception applied on tourism fields as well as introduces the theory of attachment to explain how the world is constructed.

  3. Essays on inheritance, small businesses and energy consumption

    OpenAIRE

    Escobar, Sebastian

    2017-01-01

    Essay 1: People’s planning to evade the inheritance tax curtails its merits. However, the extent of planning remains a matter of argument. According to popular belief, it is widespread, but few estimates have been presented. This study estimates the extent of estate size under-reporting, a form of inheritance tax planning, using the repeal of the Swedish tax on spousal bequests, in 2004, and a regression discontinuity design. The results show that, on average, estate sizes were 17 percent low...

  4. Three Essays on Economic Agents' Incentives and Decision Making

    OpenAIRE

    Lee, Dongryul

    2009-01-01

    This dissertation consists of three essays on theoretical analysis of economic agents' decision making and incentives. Chapter 1 gives an outline of the subjects to be examined in the subsequent chapters and shows their conclusions in brief. Chapter 2 explores the decision problem of a superordinate (a principal) regarding whether to delegate its authority or right to make a decision to a subordinate (an agent) in an organization. We first study the optimal contracting problem of the su...

  5. Three essays in labour economics and the economics of education

    OpenAIRE

    Javdani Haji, Mohsen

    2012-01-01

    This thesis consists of three empirical essays. The first chapter is focused on the economics of gender, and the other two chapters are focused on the economics of education. A common theme in all these three chapters is studying the outcomes of disadvantaged groups in society, with an eye to policy interventions that could improve these outcomes. The first chapter examines whether women face a glass ceiling in the labour market, which would imply that they are under-represented in high wag...

  6. Essays on the behavior of the oil market and OPEC

    Science.gov (United States)

    Algudhea, Salim

    This dissertation consists of three essays. The first essay is mainly concerned with investigating the risk-responsive behavior of OPEC members. Economic theory suggests that producers respond to the risk of volatile price by lowering production level. In the case of OPEC, the risk of the volatility in the price of crude oil does not seem to be a key determinant in the production decision-making process. Engineering constraints, data frequency, and political consideration may be the main causes of such a result. In the second essay, we tested the presence of the asymmetric adjustment in the cheating behavior as a result of crude oil price shocks. We utilize a set of cointegration and error correction methods that do not assume a linear adjustment to test whether cheaters within OPEC respond more to positive or negative crude oil price shocks. We conclude that cheaters respond more to negative shocks than positive shocks in oil price. The inelastic nature of demand for oil seems to play a crucial role in such asymmetric behavior. When there is a negative price shock, OPEC producers compensate for the loss in revenue by overproducing (i.e. cheat). Yet, if there is a positive shock in the price of crude oil, OPEC producers have less incentive to overproduce because of the inelastic demand for oil. The third essay is concerned with testing for the asymmetric adjustment in gasoline prices in the U.S. We consider a Momentum Threshold Autoregressive (MTAR) process to test for the asymmetric adjustment in all of the possible stages that a gallon of gasoline goes through in order to find the source of asymmetry. Then, we examine the dynamics of gasoline prices using asymmetric error correction models based on the MTAR specifications. We find the asymmetric adjustment present in all stages. The asymmetry in the retail stage seems to be the result of insufficient demand faced by retailers.

  7. Essays on the Effects of Medical Marijuana Laws

    OpenAIRE

    Smart, Rosanna

    2016-01-01

    Over half of the US states have adopted "medical marijuana" laws (MMLs), and 58% of Americans now favor marijuana legalization. Despite public support, federal law continues to prohibit the use and sale of marijuana due to public health concerns of increased dependence and abuse, youth access, and drugged driving. These essays contribute toward understanding the likely health consequences of marijuana liberalization using evidence from MMLs.Chapter 1 -- Growing Like Weed: Explaining Variation...

  8. Essays on Online and Multi-Channel Marketing

    OpenAIRE

    Zhang, Lingling

    2016-01-01

    Firms increasingly adopt online and multi-channel marketing strategies to reach and persuade consumers. Therefore, designing an effective marketing mix is critical to their success. The aim of my dissertation is to understand the strategy behind firms’ channel choices and assess marketing effectiveness. It consists of three large-scale empirical studies examining several important aspects of online and multi-channel marketing. My first essay focuses on the business-to-business (B2B) inte...

  9. Virtual Reality: A Definition History - A Personal Essay

    OpenAIRE

    Bryson, Steve

    2013-01-01

    This essay, written in 1998 by an active participant in both virtual reality development and the virtual reality definition debate, discusses the definition of the phrase "Virtual Reality" (VR). I start with history from a personal perspective, concentrating on the debate between the "Virtual Reality" and "Virtual Environment" labels in the late 1980's and early 1990's. Definitions of VR based on specific technologies are shown to be unsatisfactory. I propose the following definition of VR, b...

  10. The Organizational Approach of Capability Theory: A Review Essay

    OpenAIRE

    Garzarelli, Giampaolo

    2006-01-01

    Richard Langlois, Tony Yu & Paul Robertson have assembled a collection of previously published papers that move beyond textbook production theory. This essay discusses work by Frank Knight and Hendrik Houthakker not reproduced in LYR in relation to the capability theory of economic organization. Knight identified the problem of organization as the search for and the coordination of different dispersed capabilities. Houthakker helps us to see more clearly that the benefits of specialization ar...

  11. Pulp fictions of medieval England: Essays in popular romance

    OpenAIRE

    McDonald, Nicola

    2004-01-01

    Middle English popular romance is the most audacious and compendious testimony to the imaginary world of the English Middle Ages. Yet, with few exceptions, it remains under read and under studied. Pulp fictions of medieval England demonstrates that popular romance merits and rewards serious critical attention and that it is crucial to our understanding of the complex and conflicted world of medieval England. Pulp fictions of medieval England comprises ten essays on individual romances that, w...

  12. Essay on Methods in Futures Studies and a Selective Bibliography

    DEFF Research Database (Denmark)

    Poulsen, Claus

    2005-01-01

    Futures studies is often conflated with science fiction or pop-futurism. Consequently there is a need for demarcation of what is futures studies and what is not. From the same reason the essay stresses the need for quality control to focus on futures research and its methods: Publications in futu...... programme are (only) partly reduced by applying Causal Layered Analysis as an internal quality control. The following selective bibliography is focussed on these methodological issues...

  13. Essays on Currency Competition, Institutional Restrictions and Exchange Rates

    OpenAIRE

    Bhattacharya, Arghya

    2017-01-01

    This dissertation consists of three essays on currency competition, institutional restrictions and exchange rates. When faced with currency competition, a country's government has two tools at its disposal: reduce the level of inflation or place institutional barriers to the use of foreign currency. In the first chapter, I propose a two-country, two-currency New Monetarist model to study currency competition. I model institutional barriers as a `tax' on the real value of foreign currency hol...

  14. Unusual lesions that distend the knee joint: pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Lima, Luana T. Barros de, E-mail: luanatbl@hotmail.com [Universidade Federal de Alagoas (HUPAA/UFAL), Maceio (Brazil). Hospital Universitario; Albuquerque Filho, Eolo Santana de; Batista, Laecio Leitao [Universidade Federal de Pernambuco (UFPE), Recife (Brazil). Hospital das Clinicas; Moraes, Talita Peixoto de [Clinica Derbimagem, Recife, PE (Brazil); Pereira, Bruno Perez Guedes [Instituto de Medicina Integral Professor Fernando Figueira (IMIP), Recife, PE (Brazil)

    2016-09-15

    The high number of knee imaging exams at radiology clinics, together with the wide variety of knee disorders, calls for expanding the knowledge about the less common lesions seen in routine diagnostic practice. The purpose of this pictorial essay was to illustrate unusual lesions that distend the knee joint, selected by relevance and evaluated with multiple imaging modalities, including X-ray, computed tomography, and magnetic resonance imaging, as well as to perform a brief review of the literature. (author)

  15. Essays on electricity transmission investment and financial transmission rights

    Science.gov (United States)

    Shang, Wenzhuo

    The U.S. electric power industry has been going through fundamental restructuring and realignment since the 1990's. Many issues and problems have emerged during the transition, and both economists and engineers have been looking for the solutions fervently. In this dissertation, which consists primarily of three essays, we apply economics theory and techniques to the power industry and address two related issues, transmission investment and financial transmission rights (FTRs). The first essay takes the decentralized perspective and investigates the efficiency attribute of market-based transmission investment under perfect competition. We clarify, for the first time, the nature of the externality created by loop flows that causes transmission investment to be inefficient. Our findings have important implications for better understanding of transmission market design and creating incentives for efficient transmission investment. In the second essay, we define several rules for allocating transmission investment cost within the framework of cooperative game theory. These rules provide fair, stable or efficient cost allocations in theory and are good benchmarks against which the allocation mechanism in practice can be compared and improved upon. In the last essay, we make exploratory efforts in analyzing and assessing empirically the performance of the Midwest independent system operator (MISO) FTR auction market. We reveal some stylized facts about this young market and find that it is not efficient under the risk-neutrality assumption. We also point out and correct the drawbacks in previous related work and suggest about more complete empirical work in future. In all, this dissertation makes both theoretic and empirical analysis of the two hot issues related to the power industry and comes up with findings that have important implications for the development of this industry.

  16. Essays on Incentives and Measurement of Online Marketing Efforts

    OpenAIRE

    Berman, Ron

    2014-01-01

    This dissertation contains three essays that examine different aspects of online marketing activities, the ability of marketers to measure the effectiveness of such activities, and the design of experiments to aid in this measurement.Chapter 2 examines the impact of search engine optimization (SEO) on the competition between advertisers for organic and sponsored search results. The results show that a positive level of search engine optimization may improve the search engine's ranking quality...

  17. Three essays on the exploration for non-renewable resources

    International Nuclear Information System (INIS)

    Sadorsky, P.A.

    1990-06-01

    A new additional motive for exploration activity is proposed in the first essay. When exploration occurs before the resource is extracted, there is an incentive to use exploration activity as a strategic instrument to capture market share and inflict capital losses on rivals. This provides an incentive for governments to use strategic taxation to capture greater rents from the imperfectly competitive world output markets. Analytic expressions for the optimal domestic extraction tax and exploration subsidy are presented. In the second essay, Canadian data are used to estimate a multiple-output translog exploration cost function. A new definition of depletion is introduced and its estimated coefficient is found to be statistically significant. Monte Carlo integration techniques were applied to ensure the estimated cost function satisfies concavity and monotonicity. The fitted cost function parameters are then used to estimate the marginal cost of oil and gas exploration. These estimates are used, along with estimates of exploration rents, to measure resource scarcity. In the third essay, Canadian data are used to estimate a stochastic and dynamic model of oil exploration and extraction in Alberta. The main determinants of current period extraction are one period lagged extraction and one period expected extraction. The main determinants of current period exploration are one period lagged cumulative exploration and a relative price variable. 150 refs., 13 figs., 19 tabs

  18. Telling Lives in Science: Essays on Scientific Biography

    International Nuclear Information System (INIS)

    Harman, Peter

    1997-01-01

    This collection of ten essays by historians of science, several of them biographers, is concerned with the role of scientific biography in forming conceptions of science and scientists. The essays include studies of the biographies of individual scientists, assessments of the aims and style of scientific portraits in different historical contexts, examinations of changing biographical interpretations of scientists, and much discussion of the methodological issues involved in the writing of scientific biographies. Many historians consider biography to be an ambiguous genre, its appeal based on nostalgia rather than history, with a focus on personality rather than historical context, but the biographer can reply that scientific biography reveals the practice of science at its most fundamental level. Indeed, scientific biography has provided a powerful medium in which public conceptions of science have been established. Einstein observed that 'the essential being of a man of my type lies in what he thinks and how he thinks', and his Autobiographical Notes suppress personality in favour of physics. But the biographer may see matters differently, and wish to integrate the public and the private life of the scientist. In their substantial introduction the editors discuss these and other problems, and the book is directed to the professional concerns of historians of science. While there is little here on the history of physics, Geoffrey Cantor's essay on public images of Faraday as constructed in popular biographies, a discussion of conflicting portraits of Faraday as romantic genius or hard-working slogger, may interest readers of this journal. (book review)

  19. Assessing the use of multiple sources in student essays.

    Science.gov (United States)

    Hastings, Peter; Hughes, Simon; Magliano, Joseph P; Goldman, Susan R; Lawless, Kimberly

    2012-09-01

    The present study explored different approaches for automatically scoring student essays that were written on the basis of multiple texts. Specifically, these approaches were developed to classify whether or not important elements of the texts were present in the essays. The first was a simple pattern-matching approach called "multi-word" that allowed for flexible matching of words and phrases in the sentences. The second technique was latent semantic analysis (LSA), which was used to compare student sentences to original source sentences using its high-dimensional vector-based representation. Finally, the third was a machine-learning technique, support vector machines, which learned a classification scheme from the corpus. The results of the study suggested that the LSA-based system was superior for detecting the presence of explicit content from the texts, but the multi-word pattern-matching approach was better for detecting inferences outside or across texts. These results suggest that the best approach for analyzing essays of this nature should draw upon multiple natural language processing approaches.

  20. THE EFFECTS OF TEACHING CRITICAL THINKING ON STUDENTS’ ARGUMENTATIVE ESSAY

    Directory of Open Access Journals (Sweden)

    A’am Rifaldi Khunaifi

    2015-03-01

    Full Text Available This study is directed to find out whether teaching critical thinking affects the writing ability of argumentative essay. This research employed quasi experimental design as it was intended to measure the effects of the strategy on the students’ ability in writing argumentative essay. The samples of the study were the students of class A and B enrolled in the seventh semester of the English Education Department of State Islamic College of Palangka Raya. To collect the data needed, it was used test as the instrument; it was Academic Writing for IELTS Test. The data were processed and analyzed by using SPSS 19.0 statistic technique of independent t-test and paired-sample t-test, and the analized data were concluded. From the result of the test, the independent t-test calculation in posttest scores in both groups shows that the significance value is higher than level of significance (0.194 > 0.05. It indicates that there is no significant difference between experimental and control groups. Moreover, the paired t-test calculation shows the result of paired sample test (0.000 < 0.05 in which there is a significant difference between pretest and posttest scores in experimental group after having treatments. Keywords: critical thinking, writing ability, argumentative essay

  1. Application essays and future performance in medical school: are they related?

    Science.gov (United States)

    Dong, Ting; Kay, Allen; Artino, Anthony R; Gilliland, William R; Waechter, Donna M; Cruess, David; DeZee, Kent J; Durning, Steven J

    2013-01-01

    There is a paucity of research on whether application essays are a valid indicator of medical students' future performance. The goal is to score medical school application essays systematically and examine the correlations between these essay scores and several indicators of student performance during medical school and internship. A journalist created a scoring rubric based on the journalism literature and scored 2 required essays of students admitted to our university in 1 year (N = 145). We picked 7 indicators of medical school and internship performance and correlated these measures with overall essay scores: preclinical medical school grade point average (GPA), clinical medical school GPA, cumulative medical school GPA, U.S. Medical Licensing Exam (USMLE) Step 1 and 2 scores, and scores on a program director's evaluation measuring intern professionalism and expertise. We then examined the Pearson and Spearman correlations between essay scores and the outcomes. Essay scores did not vary widely. American Medical College Application Service essay scores ranged from 3.3 to 4.5 (M = 4.11, SD = 0.15), and Uniformed Services University of the Health Sciences essay scores ranged from 2.9 to 4.5 (M = 4.09, SD = 0.17). None of the medical school or internship performance indicators was significantly correlated with the essay scores. These findings raise questions about the utility of matriculation essays, a resource-intensive admission requirement.

  2. Re-Theorizing the Role of Creative Writing in Composition Studies: Cautionary Notes towards Re-Thinking the Essay in the Teaching of Writing.

    Science.gov (United States)

    Julier, Laura

    An essay, often called a personal essay, familiar essay, lyric essay, the disjunctive or spiral essay, is a piece of writing which takes its form in the shifts and turns of a particular mind at work. The essay is a piece of writing which pays attention to and sometimes plays with form; often uses images and figures that are familiar with poetry;…

  3. Genetics Home Reference: myotonia congenita

    Science.gov (United States)

    ... Manual Consumer Version: Congenital Myopathies Orphanet: Thomsen and Becker disease Patient Support and Advocacy Resources (3 links) Muscular Dystrophy Association National Organization for Rare Disorders (NORD) Resource ...

  4. Genetics Home Reference: pachyonychia congenita

    Science.gov (United States)

    ... 27 [updated 2014 Jul 24]. In: Pagon RA, Adam MP, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Ledbetter N, Mefford HC, Smith RJH, Stephens K, editors. GeneReviews® [Internet]. Seattle (WA): ...

  5. Pachyonychia Congenita and Mental Deficiency

    Directory of Open Access Journals (Sweden)

    V Ramesh

    1988-01-01

    Full Text Available Pachyonychia congenital was seen in two different families. In one family the disease was present in only one child, while in the other family the disease was traceable in 5 generations involving 36 members. One individual had associated mental retardation.

  6. MRI findings of congenita dysosmia

    International Nuclear Information System (INIS)

    You Hui; Feng Feng; Liu Jianfeng; Wu Xueyan; Wang Jian; Ni Daofeng; Sun Hongyi; Chen Jun; Jin Zhengyu

    2009-01-01

    Objective: To study the MRI findings of congenital dysosmia. Methods: Forty-seven patients with congenital dysosmia (39 with Kallmann syndrome and 8 with isolated dysosmia) and 21 normal volunteers underwent MRI examination. The features of congenital malformation were recorded. The volume of olfactory bulbs, depth of olfactory sulci as well as diameters of pituitary glands and stalks were measured. The rate of dysplasia of olfactory bulbs and tracts in the two patients groups was compared with X 2 test. The difference of volume of olfactory bulbs between the two groups was evaluated with nonparametric test. And the difference of diameters of pituitary glands and stalks was analyzed with analysis of variance. Results: All the patients had abnormal findings in olfactory bulbs, tracts and/or olfactory sulci on MR images. The patterns of congenital malformation may be dysplastic of hypoplastic, symmetric or asymmetric. The proportion of patients with dysplasia of olfactory bulbs and tracts in Kallmann syndrome patients (31/39) was higher than that in isolated dysosmia ones (2/8) (X 2 = 6.998, P =0.008), and the olfactory bulbs'volume of patients with Kallmann syndrome (median 8 mm 3 ) was smaller than that of patients with isolated dysosmia (median 22 mm 3 ) (Z = -2.902, P =0.004). The pituitary glands were smaller and the stalks were thinner in patients with Kallmann syndrome than those in volunteers [ the anteroposterior diameter of pituitary glands in Kallmann syndrome (7.22 ± 1.93) mm, that in normal volunteers (9.94 ± 1.59) mm, F= 16.835, P =0.000; height of pituitary glands in Kallmann syndrome (3.71 ± 1.74) mm, that in normal volunteers (6.00 ± 1.24) mm, F =16.092, P =0.000; the anteroposterior diameter of pituitary stalks in Kallmann syndrome (1.19 ± 0.55) mm, that in normal volunteers (1.88 ± 0.49) mm, F =13.060, P =0.000]. Conclusions: In congenital dysosmic patients, dysplasia or hypoplasia of olfactory bulbs, tracts and sulci can be clearly depicted on MR images. MR imaging is valuable for clinical diagnosis and treatment. (authors)

  7. Essays on energy, equity, and the environment in developing countries

    Science.gov (United States)

    Israel, Debra Kim

    1999-11-01

    The essays in this dissertation explore different environmental and public policy issues relevant to developing countries. Essay I examines household-level survey responses to the question "How willing would you be to pay somewhat higher taxes to the government if you knew the money would be spent to protect the environment and prevent land, water and air pollution?" Specifically, for twelve developing and three developed countries included in the survey, the empirical relationships among willingness to pay for environmental quality, relative household income and national income are investigated. The results indicate that when the effects of household and national income are combined, households with below-average income in low-income countries are less willing to pay for environmental protection than those with above-average income in high-income countries. Furthermore, willingness to pay for environmental protection increases more significantly with relative household income than with national income. Essay II uses data from urban Bolivia to study the determinants of household fuel choice, an important link between deforestation and indoor air pollution in developing countries. In particular, the effects of fixed fuel costs, income growth, and female earned income on household fuel choice are examined. The results imply that reduction in firewood use in developing countries is not likely to occur simply as the result of income growth. The essay discusses possible policy implications based on the results that fixed fuel costs appear to be a deterrent to switching to a cleaner fuel and households with female earned income seem less likely to use firewood than other households. Essay III analyzes the equity implications of the elimination of fuel subsidies in the 1985 Bolivian economic reforms. An analysis of the direct static burden shows that while the elimination of gasoline subsidies was progressively distributed, the elimination of LPG and kerosene subsidies

  8. The SAT® Essay and College Performance: Understanding What Essay Scores Add to HSGPA and SAT. Research Report 2012-9 (REV: 4-2013)

    Science.gov (United States)

    Shaw, Emily J.; Kobrin, Jennifer L.

    2013-01-01

    This study examines the relationship between students' SAT essay scores and college outcomes, including first-year grade point average (FYGPA) and first-year English course grade average (FY EngGPA), overall and by various demographic and academic performance subgroups. Results showed that the SAT essay score has a positive relationship with both…

  9. Study of the density of ganglion cells in the terminal bowel of rats with anorectal malformations Estudo da densidade das células ganglionares no intestino terminal de ratos portadores de anomalia anorretal

    Directory of Open Access Journals (Sweden)

    Maurício Macedo

    2007-12-01

    Full Text Available PURPOSE: To study the ganglion cells (GC in the terminal bowel of rats with ethylenethiourea (ETU induced anorectal malformations (ARM. METHODS: The animals were divided into three groups: Group A - normal fetuses from pregnant rats that were not administered ETU; Group B - fetuses without ARM born from pregnant rats that were administered ETU and Group C - fetuses with ARM born from pregnant rats that received ETU. ETU was administered on the 11th day of pregnancy at the dose of 125 mg/kg body weight by gastric gavage. The rats had cesarean section on the 21st day of gestation. The fetuses’ terminal bowel tissue was analyzed by immunohistochemistry to demonstrate ganglion cells. RESULTS: Statistically significant differences were found between groups A, B and C regarding ganglion cell densities. Group A had the highest cell density, followed by Group B and the lowest density was found in Group C. CONCLUSION: Ganglion cell densities are decreased in the terminal bowel of rats with ARM.OBJETIVO: Estudar as células ganglionares (CG no intestino terminal de ratos portadores de anomalia anorretal (AAR induzida pela etilenotiouréia (ETU. MÉTODOS: Os animais foram distribuídos em três grupos: Grupo A - fetos normais, obtidos de ratas grávidas às quais não foi administrada ETU; Grupo B - fetos não portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU e Grupo C - fetos portadores de AAR obtidos de ratas grávidas às quais foi administrada ETU. A ETU foi administrada no décimo primeiro dia de gestação na dose de 125 mg/Kg, por gavagem. As ratas foram submetidas à laparotomia e histerotomia para retirada dos fetos no vigésimo primeiro dia de gestação. O intestino terminal dos fetos foi retirado e analisado por imunohistoquímica para pesquisa de CG. RESULTADOS: Foram encontradas diferenças estatisticamente significantes entre os grupos A, B e C quanto à densidade de CG. O grupo A apresentou a maior densidade

  10. Clinical and molecular diagnosis of a Costa Rican family with autosomal recessive myotonia congenita (Becker disease carrying a new mutation in the CLCN1 gene

    Directory of Open Access Journals (Sweden)

    Fernando Morales

    2008-03-01

    Full Text Available Myotonia congenita is a muscular disease characterized by myotonia, hypertrophy, and stiffness. It is inherited as either autosomal dominant or recessive known as Thomsen and Becker diseases, respectively. Here we confirm the clinical diagnosis of a family diagnosed with a myotonic condition many years ago and report a new mutation in the CLCN1 gene. The clinical diagnosis was established using ocular, cardiac, neurological and electrophysiological tests and the molecular diagnosis was done by PCR, SSCP and sequencing of the CLCN1 gene. The proband and the other affected individuals exhibited proximal and distal muscle weakness but no hypertrophy or muscular pain was found. The myotatic reflexes were lessened and sensibility was normal. Electrical and clinical myotonia was found only in the sufferers. Slit lamp and electrocardiogram tests were normal. Two affected probands presented diminution of the sensitive conduction velocities and prolonged sensory distal latencies. The clinical spectrum for this family is in agreement with a clinical diagnosis of Becker myotonia. This was confirmed by molecular diagnosis where a new disease-causing mutation (Q412P was found in the family and absent in 200 unaffected chromosomes. No latent myotonia was found in this family; therefore the ability to cause this subclinical sign might be intrinsic to each mutation. Implications of the structure-function-genotype relationship for this and other mutations are discussed. Adequate clinical diagnosis of a neuromuscular disorder would allow focusing the molecular studies toward the confirmation of the initial diagnosis, leading to a proper clinical management, genetic counseling and improving in the quality of life of the patients and relatives. Rev. Biol. Trop. 56 (1: 1-11. Epub 2008 March 31.La miotonía congénita es una enfermedad muscular caracterizada por miotonía, hipertrofia y rigidez. Se presenta con dos patrones de herencia, autosómica dominante en cuyo

  11. Telling Lives in Science: Essays on Scientific Biography

    Energy Technology Data Exchange (ETDEWEB)

    Harman, Peter

    1997-09-01

    This collection of ten essays by historians of science, several of them biographers, is concerned with the role of scientific biography in forming conceptions of science and scientists. The essays include studies of the biographies of individual scientists, assessments of the aims and style of scientific portraits in different historical contexts, examinations of changing biographical interpretations of scientists, and much discussion of the methodological issues involved in the writing of scientific biographies. Many historians consider biography to be an ambiguous genre, its appeal based on nostalgia rather than history, with a focus on personality rather than historical context, but the biographer can reply that scientific biography reveals the practice of science at its most fundamental level. Indeed, scientific biography has provided a powerful medium in which public conceptions of science have been established. Einstein observed that 'the essential being of a man of my type lies in what he thinks and how he thinks', and his Autobiographical Notes suppress personality in favour of physics. But the biographer may see matters differently, and wish to integrate the public and the private life of the scientist. In their substantial introduction the editors discuss these and other problems, and the book is directed to the professional concerns of historians of science. While there is little here on the history of physics, Geoffrey Cantor's essay on public images of Faraday as constructed in popular biographies, a discussion of conflicting portraits of Faraday as romantic genius or hard-working slogger, may interest readers of this journal. (book review)

  12. Essays in Energy Policy: The Interplay Between Risks and Incentives

    Science.gov (United States)

    Lordan-Perret, Rebecca Jane Bishop

    My dissertation considers examples of how social, economic, and political incentives associated with energy production, distribution, and consumption increase the risk of harm to society and the environment. In the first essay, "Why America should move toward dry cask consolidated interim storage of used nuclear fuel," my co-authors and I discuss how the confluence of the U.S. Government and electricity utilities' political and economic incentives created a gridlock preventing a long-term nuclear waste disposal solution. We find that our current policies undermine the safety and security of the nuclear waste, and so, suggest a temporary, consolidated storage solution. In the second essay, "Import-Adjusted Fatality Rates for Individual OECD Countries Caused by Accidents in the Oil Energy Chain," my co-authors and I adopt a technique from the greenhouse gas accounting literature and assign CO2 emissions to the final consumer (rather than the producer) by allocating the risk - measured in fatalities - associated with oil production to the final consumer. The new assignments show that normal methods of tracking oil production impacts only capture part of the actual costs. In the third essay, "Insurgent Attacks on Energy Infrastructure and Electoral Institutions in Colombia," my co-authors and I consider the economic and political incentives that an energy resource create in a conflict environment. Our research shows that insurgents in Colombia, Las Fuerzas Armadas Revolucionarias de Colombia (FARC) and Ejercito de Liberacion Nacional (ELN), strategically time attacks on critical energy infrastructure during elections. These results are the first to quantify insurgent tactics to target critical energy infrastructure, which potentially undermine state capacity and democratic processes.

  13. Essays on the future in honor of Nick Metropolis

    CERN Document Server

    Rota, Gian-Carlo

    2000-01-01

    This collection represents a unique undertaking in scientific publishing to honor Nick Metropolis. Nick was the last survivor of the World War II Manhattan Project in Los Alamos, and was an important member of the Los Alamos national Laboratory until his death in October, 1999. In this volume, some of the leading scientists and humanists of our time have contributed essays related to their respective disciplines, exploring various aspects of future developments in science and society, philosophy, national security, nuclear power, pure and applied mathematics, physics and biology, particle physics, computing, and information science.

  14. Imaging Findings of Scrotal Tumors in Children: A Pictorial Essay

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Myung Hee [Kang-Dong Hospital, Busan (Korea, Republic of); Kim, Jee Eun [Gachon University, Gil Hospital, Incheon (Korea, Republic of); Kim, Ji Hye [Sungkyunkwan University, Samsung Medical Center, Changwon (Korea, Republic of); Yang, Dal Mo [Kyung Hee University Hospital at Gangdong, Seoul (Korea, Republic of)

    2011-12-15

    The diagnosis of scrotal tumors in children can be challenging because of the rarity, vague symptoms, and varied imaging features of the tumors. The pathology and frequency of scrotal tumors that occur in children are different from tumors that arise in adults. In this pictorial essay, we illustrate the imaging findings of scrotal tumors in children with pathological correlations. In addition, we present the clinical manifestations that are valuable for a differential diagnosis. Familiarity with the imaging findings and clinical manifestations of pediatric scrotal tumors may be helpful in making an accurate diagnosis and providing proper patient management

  15. Magnetic resonance imaging in lower urinary tract endometriosis: iconographic essay

    International Nuclear Information System (INIS)

    Lima, Claudio Marcio Amaral de Oliveira; Coutinho, Elisa Pompeu Dias; Ribeiro, Erica Barreiros; Domingues, Marisa Nassar Aidar; Junqueira, Flavia Pegado; Coutinho Junior, Antonio Carlos

    2009-01-01

    Endometriosis is defined as the presence of functional endometrial tissue outside the endometrial cavity and myometrium. Although this is a frequent disease with multifactorial causes, involvement of the lower urinary tract is rare. Magnetic resonance imaging is highly sensitive, specific and accurate in the diagnosis of endometriosis in the lower urinary tract, especially for allowing the identification of lesions obscured by adhesions or with subperitoneal extension. The present iconographic essay presents the main magnetic resonance imaging findings of the lower urinary tract involvement by endometriosis. (author)

  16. Essays in theoretical physics in honour of Dirk Ter Haar

    CERN Document Server

    Parry, W E

    2013-01-01

    Essays in Theoretical Physics: In Honour of Dirk ter Haar is devoted to Dirk ter Haar, detailing the breadth of Dirk's interest in physics. The book contains 15 chapters, with some chapters elucidating stellar dynamics with non-classical integrals; a mean-field treatment of charge density waves in a strong magnetic field; electrodynamics of two-dimensional (surface) superconductors; and the Bethe Ansatz and exact solutions of the Kondo and related magnetic impurity models. Other chapters focus on probing the interiors of neutron stars; macroscopic quantum tunneling; unitary transformation meth

  17. [Suicide -- an essay trying to reveal the theme].

    Science.gov (United States)

    Sampaio, M A; Boemer, M R

    2000-12-01

    This essay proposes to reveal facets of the suicide through the discourse of different authors treating this theme as well as through contacts that I was able to have in my nursing training, through my academic trajectory. This trajectory includes an incursion by phenomenological ideas, mainly by the ideas of Heidegger and his existential analysis of the man as being-there. In this way, the understanding of a person who decides to finalize his/her existence, can be, by the existential analysis perspective, a way to reconstruct and redimension his/her existential perspectives.

  18. Ten mathematical essays on approximation in analysis and topology

    CERN Document Server

    López-Gómez, J; Ruiz del Portal, F R

    2005-01-01

    This book collects 10 mathematical essays on approximation in Analysis and Topology by some of the most influent mathematicians of the last third of the 20th Century. Besides the papers contain the very ultimate results in each of their respective fields, many of them also include a series of historical remarks about the state of mathematics at the time they found their most celebrated results, as well as some of their personal circumstances originating them, which makes particularly attractive the book for all scientist interested in these fields, from beginners to experts. These gem pieces

  19. Blazing the trail essays by leading women in science

    CERN Document Server

    Ideal, Emma

    2013-01-01

    Name a famous scientist. Got one? Now name a famous physicist. Ok, now name a famous female physicist. Ok, now name a famous living female physicist. Stumped? In Blazing the Trail: Essays by Leading Women in Science, 35 highly successful physicists, engineers, and chemists share their personal histories, their passion for discovery, and their secrets for success with the next generation. Essayists candidly recount their experiences – both positive and negative – with an uplifting tone, focusing on lessons learned along the way. The combination of personal stories and advice sends a powerful message to all young women considering scientific careers: I did it, so can you. Here’s how.

  20. On Voting, Violence, and Health: Essays on Political Economics and Development

    OpenAIRE

    Leon, Gianmarco

    2012-01-01

    The three essays conforming this thesis are representative pieces of my approach to analyzing the causes and consequences of economic underdevelopment. The overaching topic that ties together these essays is role that institutions and culture play in affecting specific behaviors that undermine development. The approach to the questions addressed in each essay is empirical, using data from Per\\'{u} and Sierra Leone, and relies on economic theory to provide a general framework and deepen our un...

  1. An essay on the importance of being nonlinear

    CERN Document Server

    West, Bruce J

    1985-01-01

    One of my favorite quotes is from a letter of Charles Darwin (1887): "I have long discovered that geologists never read each other's works, and that the only object in writing a book is proof of earnestness, and that you do not form your opinions without undergoing labour of some kind. " It is not clear if this private opinion of Darwin was one that he held to be absolutely true, or was one of those opinions that, as with most of us, coincides with our "bad days," but is replaced with a more optimistic view on our "good days. " I hold the sense of the statement to be true in general, but not with regard to scientists never reading each other's work. Even if that were true however, the present essay. would still have been written as a proof of earnestness. This essay outlines my personal view of how nonlinear mathematics may be of value in formulating models outside the physical sciences. This perspective has developed over a number of years during which time I have repeatedly been amazed at how an "accepted" ...

  2. Essays on market design and strategic behaviour in energy markets

    International Nuclear Information System (INIS)

    Lorenczik, Stefan

    2017-01-01

    The thesis at hand consists of four essays which are divided into two parts. In the first part, consisting of the first two essays, market design issues in electricity markets are discussed. More precisely, it deals with concerns regarding security of supply: First, the concerns regarding the availability of sufficient flexibility to cope with intermittent renewable energy electricity generation. And second, the consequences of insufficient investments signals in energy only markets in interconnected electricity markets. Part two deals with strategic behaviour in spatial natural resource markets. Strategic behaviour and the exertion of market power have always been a matter of concern in energy markets, especially in natural resource markets. The exertion of market power can result in deadweight losses - regulatory bodies try to address this by market regulations aiming for a welfare maximising market outcome. The first problem is to detect collusive behaviour as available data is frequently limited. The second question is how regulatory decisions may influence the market outcome. Both topics are investigated by using the example of the international metallurgical coal market.

  3. Essays on market design and strategic behaviour in energy markets

    Energy Technology Data Exchange (ETDEWEB)

    Lorenczik, Stefan

    2017-11-13

    The thesis at hand consists of four essays which are divided into two parts. In the first part, consisting of the first two essays, market design issues in electricity markets are discussed. More precisely, it deals with concerns regarding security of supply: First, the concerns regarding the availability of sufficient flexibility to cope with intermittent renewable energy electricity generation. And second, the consequences of insufficient investments signals in energy only markets in interconnected electricity markets. Part two deals with strategic behaviour in spatial natural resource markets. Strategic behaviour and the exertion of market power have always been a matter of concern in energy markets, especially in natural resource markets. The exertion of market power can result in deadweight losses - regulatory bodies try to address this by market regulations aiming for a welfare maximising market outcome. The first problem is to detect collusive behaviour as available data is frequently limited. The second question is how regulatory decisions may influence the market outcome. Both topics are investigated by using the example of the international metallurgical coal market.

  4. Improving Undergraduates’ Argumentative Group Essay Writing through Self-assessment

    Directory of Open Access Journals (Sweden)

    Yong Mei Fung

    2015-10-01

    Full Text Available When writing an argumentative essay, writers develop and evaluate arguments to embody, initiate, or simulate various kinds of interpersonal and textual interaction for reader consideration (Wu & Allison, 2003. This is quite challenging for English as a second language (ESL learners. To improve the quality of their writing, students need to review their draft throughout the writing process. This study aimed to investigate the effect of self-assessment in group writing and how group work improves students’ writing ability. An intact class comprising 22 first-year undergraduates participated in the study.  Data were collected from pre- and post-treatment writing tests, semi-structured interview and reflection entries. The results revealed that self-assessment has a significant effect on students’ writing performance. Group work also enhanced social and cognitive development of the students. This study provides insights into the use of self-assessment in writing class to develop learner autonomy and improve writing ability. Keywords: Argumentative essay, Self-assessment, Learner autonomy, Group writing, ESL learners

  5. Essays on carbon policy and enhanced oil recovery

    Science.gov (United States)

    Cook, Benjamin R.

    The growing concerns about climate change have led policy makers to consider various regulatory schemes designed to reduce the stock and growth of atmospheric CO2 concentrations while at the same time improving energy security. The most prominent proposals are the so called "cap-and-trade" frameworks which set aggregate emission levels for a jurisdiction and then issue or sell a corresponding number of allowances to emitters. Typically, these policy measures will also encourage the deployment of carbon capture and storage (CCS) in geological formations and mature oil fields through subsidies or other incentives. The ability to store CO 2 in mature oil fields through the deployment of CO2 enhanced oil recovery (CO2--EOR) is particularly attractive as it can simultaneously improve oil recovery at those fields, and serve as a possible financial bridge to the development of CO2 transportation infrastructure. The purpose of this research is to explore the impact that a tandem subsidy-tax policy regime may have on bargaining between emitters and sequestration providers, and also to identify oil units in Wyoming that can profitably undertake CO 2--EOR as a starting point for the build-out of CO2 pipelines. In the first essay an economics lab experiment is designed to simulate private bargaining between carbon emitters (such as power plants) and carbon sequestration sites when the emitter faces carbon taxes, sequestration subsidies or both. In a tax-subsidy policy regime the carbon tax (or purchased allowances) can be avoided by sequestering the carbon, and in some cases the emitter can also earn a subsidy to help pay for the sequestration. The main policy implications of the experiment results are that the sequestration market might be inefficient, and sequestration providers seem to have bargaining power sufficient to command high prices. This may lead to the integration of CO2 sources and sequestration sites, and reduced prices for the injectable CO2 purchased by oil

  6. The C-terminal extension unique to the long isoform of the shelterin component TIN2 enhances its interaction with TRF2 in a phosphorylation- and dyskeratosis congenita-cluster-dependent fashion.

    Science.gov (United States)

    Nelson, Nya D; Dodson, Lois M; Escudero, Laura; Sukumar, Ann T; Williams, Christopher L; Mihalek, Ivana; Baldan, Alessandro; Baird, Duncan M; Bertuch, Alison A

    2018-03-26

    TIN2 is central to the shelterin complex, linking the telomeric proteins TRF1 and TRF2 with TPP1/POT1. Mutations in TINF2 , which encodes TIN2, that are found in dyskeratosis congenita (DC) result in very short telomeres and cluster in a region shared by the two TIN2 isoforms, TIN2S (short) and TIN2L (long). Here we show that TIN2L, but not TIN2S, is phosphorylated. TRF2 interacts more with TIN2L than TIN2S, and both the DC-cluster and phosphorylation promote this enhanced interaction. The binding of TIN2L, but not TIN2S, is affected by TRF2-F120, which is also required for TRF2's interaction with end processing factors such as Apollo. Conversely, TRF1 interacts more with TIN2S than with TIN2L. A DC-associated mutation further reduces TIN2L-TRF1, but not TIN2S-TRF1, interaction. Cells overexpressing TIN2L or phosphomimetic-TIN2L are permissive to telomere elongation, whereas cells overexpressing TIN2S or phosphodead-TIN2L are not. Telomere lengths are unchanged in cell lines in which TIN2L expression has been eliminated by CRISPR/Cas9-mediated mutation. These results indicate that TIN2 isoforms are biochemically and functionally distinguishable, and that shelterin composition could be fundamentally altered in patients with TINF2 mutations. Copyright © 2018 Nelson et al.

  7. Central nervous system abnormalities on midline facial defects with hypertelorism detected by magnetic resonance image and computed tomography Anomalias de sistema nervoso central em defeitos de linha média facial com hipertelorismo detectados por ressonância magnética e tomografia computadorizada

    Directory of Open Access Journals (Sweden)

    Vera Lúcia Gil-da-Silva-Lopes

    2006-12-01

    Full Text Available The aim of this study were to describe and to compare structural central nervous system (CNS anomalies detected by magnetic resonance image (MRI and computed tomography (CT in individuals affected by midline facial defects with hypertelorism (MFDH isolated or associated with multiple congenital anomalies (MCA. The investigation protocol included dysmorphological examination, skull and facial X-rays, brain CT and/or MRI. We studied 24 individuals, 12 of them had an isolated form (Group I and the others, MCA with unknown etiology (Group II. There was no significative difference between Group I and II and the results are presented in set. In addition to the several CNS anomalies previously described, MRI (n=18 was useful for detection of neuronal migration errors. These data suggested that structural CNS anomalies and MFDH seem to have an intrinsic embryological relationship, which should be taken in account during the clinical follow-up.Este estudo objetivou descrever e comparar as anomalias estruturais do sistema nervoso central (SNC detectadas por meio de ressonância magnética (RM e tomografia computadorizada (TC de crânio em indivíduos com defeitos de linha média facial com hipertelorismo (DLMFH isolados ou associados a anomalias congênitas múltiplas (ACM. O protocolo de investigação incluiu exame dismorfológico, RX de crânio e face, CT e RM de crânio. Foram estudados 24 indivíduos, sendo que 12 apresentavam a forma isolada (Grupo I e os demais, DLMFH com ACM de etiologia não esclarecida (Grupo II. Não houve diferença entre os dois grupos e os resultados foram agrupados. Além de várias anomalias de SNC já descritas, a RM foi útil para detecção de erros de migração neuronal. Os dados sugerem que as alterações estruturais de SNC e os DLMFH têm relação embriológica, o que deve ser levado em conta durante o seguimento clínico.

  8. Towards a sustainable agriculture in 2030. An essay on transition; Naar een duurzame landbouw in 2030. Een essay over transitie

    Energy Technology Data Exchange (ETDEWEB)

    Hees, E.M.; Van der Weijden, W.J.; Hin, C.J.A.

    2002-05-01

    Sustainable development of the agricultural sector in the Netherlands is high on the list of priorities in the environmental policy of the Netherlands. In this report special attention is paid to sustainability indicators which can be used in the transition of a Dutch National Environmental Balance towards a Dutch National Sustainability Balance. The report consists of three parts: (1) an essay in the form of an imaginary review from the year 2030 back to the transition process of the agricultural sector from the year 2000 onwards; (2) 14 texts on proposals for economical, socio-cultural and ecological indicators; and (3) four maps which present chances for offering 'green' services in Dutch agricultural areas. [Dutch] Een van de sectoren waar duurzame ontwikkeling hard nodig is, is de landbouw. Het 4e Nationaal Miliebeleidsplan (NMP4) noernt de landbouw naast de energiesector en biodiversiteit als een prioritaire sector. In dit rapport is een visie neergelegdeen met speciale aandacht voor duurzaamheidindicatoren. Die indicatoren zouden bouwstenen kunnen zijn voor de voorgenomen overgang van een Nationale Milieubalans naar een Nationale Duurzaamheidsbalans. Dit rapport bestaat uit drie uiteenlopende delen: een essay in de vorm van een denkbeeldige terugblik vanuit het jaar 2030 naar het transitieproces dat de landbouw vanaf 2000 heeft doorgemaakt; een 14-tal tekstuele bijIagen, met onder meer voorstellen voor te hanteren economische, sociaal-culturele en ecologische indicatoren; en een viertal kaart-bijlagen waarop staat aangegeven waar in het Nederlandse landbouwareaal kansen liggen voor groene diensten.

  9. Essays on environmental, energy, and natural resource economics

    Science.gov (United States)

    Zhang, Fan

    My dissertation focuses on examining the interrelationship among the environment, energy and economic development. In the first essay, I explore the effects of increased uncertainty over future output prices, input costs and productivity levels on intertemporal emission permits trading. In a dynamic programming setting, a permit price is a convex function of each of these three sources of uncertainty. Increased uncertainty about future market conditions increases the expected permit price and causes risk-neutral firms to reduce ex ante emissions to smooth marginal abatement costs over time. Empirical analysis shows that increased price volatility induced by electricity market restructuring could explain 8-11% of the allowances banked during Phase I of the U.S. sulfur dioxide trading program. Numerical simulation suggests that high uncertainty may generate substantial initial compliance costs, thereby deterring new entrants and reducing efficiency; sharp emission spikes are also more likely to occur under industry-wide uncertainty shocks. In the second essay, I examine whether electricity restructuring improves the efficiency of U.S. nuclear power generation. Based on the full sample of 73 investor-owned nuclear plants in the United States from 1992 to 1998, I estimate cross-sectional and longitudinal efficiency changes associated with restructuring, at the plant level. Various modeling strategies are presented to deal with the policy endogeneity bias that high cost plants are more likely to be restructured. Overall, I find a strikingly positive relationship between the multiple steps of restructuring and plant operating efficiency. In the third essay, I estimate the economic impact of China's national land conversion program on local farm-dependent economies. The impact of the program on 14 industrial sectors in Gansu provinces are investigated using an input-output model. Due to regulatory restrictions, the agricultural sector cannot automatically expand or shrink

  10. Anomalia de Ebstein em paciente adulto: valvuloplastia modificada para correção de insuficiência tricúspide Ebstein's anomaly in adult patients: modified repair technique for tricuspid insufficiency

    Directory of Open Access Journals (Sweden)

    Mauro Barbosa ARRUDA FILHO

    2002-06-01

    Full Text Available OBJETIVOS: Avaliar a correção cirúrgica em pacientes adultos portadores de anomalia de Ebstein, utilizando uma variação técnica para correção da insuficiência tricúspide. CASUÍSTICA E MÉTODOS: Entre janeiro de 1990 e março de 2001, seis pacientes adultos foram submetidos à correção cirúrgica com uma variação da técnica apresentada por Carpentier. A idade variou de 18 a 34 anos. Todos se apresentavam em classe funcional III ou IV (NYHA, com piora da cianose ou arritmias freqüentes. Em quatro pacientes a valva tricúspide era do tipo B e em dois do tipo A (Carpentier, quatro apresentavam comunicação interatrial (CIA associada. O hematócrito variou de 33% a 68%. O índice cardíaco variou de 0.47 a 0.88. A fração de ejeção do ventrículo esquerdo variou de 50% a 80%. RESULTADOS: Não se registrou óbitos no período hospitalar. Um paciente foi reoperado por sangramento no pós-operatório imediato. Em dois pacientes ocorreram derrames pericárdicos de repetição. Foi registrado um óbito no 14º mês de pós-operatório por morte súbita. Os pacientes foram seguidos por um período de 10 a 108 meses. Quatro encontram-se em classe funcional I e um encontra-se em classe funcional II (NYHA. O ecocardiograma no pós-operatório imediato e na última avaliação mostra insuficiência tricúspide discreta ou moderada em quatro e importante em um paciente. CONCLUSÃO: Apesar do pequeno número de pacientes nesta série, a modificação técnica cumpriu o seu papel, com a melhora clínica e funcional dos pacientes tratados em até nove anos de seguimento.PURPOSE: To value the surgical treatment of adult patients with Ebstein's anomaly, using a Carpentier's modified repair technique. MATERIAL AND METHODS: Between January 1990 and March 2001 six adult patients with Ebstein's anomaly were treated using a modification of Carpentier's repair technique, four were males and two were females, ages ranging from 18 to 34 years (Mean 23

  11. Et essay om konkurrenceevnens mangfoldige rødder

    DEFF Research Database (Denmark)

    Pedersen, Kurt

    2012-01-01

    Konkurrenceevnen dukker jævnligt op i den politiske og økonomiske debat. Spørger man til, hvad det er for en størrelse, får man et mere eller mindre kompliceret indeks, der viser hvordan valutakurs og nominalløn har udviklet sig over en periode i forhold til vore samhandelspartnere. Det er...... ændringen i vor konkurrenceevne, der finder udtryk, ikke begrebet som sådant. I dette lille essay anlægges en bred teorihistorisk vinkel med henblik på at få begrebet som sådant indkredset. Dets eklektiske natur afskærer os dog fra at angive en mere præcis definition....

  12. Splenic Anomalies of Shape, Size, and Location: Pictorial Essay

    Directory of Open Access Journals (Sweden)

    Adalet Elcin Yildiz

    2013-01-01

    Full Text Available Spleen can have a wide range of anomalies including its shape, location, number, and size. Although most of these anomalies are congenital, there are also acquired types. Congenital anomalies affecting the shape of spleen are lobulations, notches, and clefts; the fusion and location anomalies of spleen are accessory spleen, splenopancreatic fusion, and wandering spleen; polysplenia can be associated with a syndrome. Splenosis and small spleen are acquired anomalies which are caused by trauma and sickle cell disease, respectively. These anomalies can be detected easily by using different imaging modalities including ultrasonography, computed tomography, magnetic resonance imaging, and also Tc-99m scintigraphy. In this pictorial essay, we review the imaging findings of these anomalies which can cause diagnostic pitfalls and be interpreted as pathologic processes.

  13. Essays on variational approximation techniques for stochastic optimization problems

    Science.gov (United States)

    Deride Silva, Julio A.

    This dissertation presents five essays on approximation and modeling techniques, based on variational analysis, applied to stochastic optimization problems. It is divided into two parts, where the first is devoted to equilibrium problems and maxinf optimization, and the second corresponds to two essays in statistics and uncertainty modeling. Stochastic optimization lies at the core of this research as we were interested in relevant equilibrium applications that contain an uncertain component, and the design of a solution strategy. In addition, every stochastic optimization problem relies heavily on the underlying probability distribution that models the uncertainty. We studied these distributions, in particular, their design process and theoretical properties such as their convergence. Finally, the last aspect of stochastic optimization that we covered is the scenario creation problem, in which we described a procedure based on a probabilistic model to create scenarios for the applied problem of power estimation of renewable energies. In the first part, Equilibrium problems and maxinf optimization, we considered three Walrasian equilibrium problems: from economics, we studied a stochastic general equilibrium problem in a pure exchange economy, described in Chapter 3, and a stochastic general equilibrium with financial contracts, in Chapter 4; finally from engineering, we studied an infrastructure planning problem in Chapter 5. We stated these problems as belonging to the maxinf optimization class and, in each instance, we provided an approximation scheme based on the notion of lopsided convergence and non-concave duality. This strategy is the foundation of the augmented Walrasian algorithm, whose convergence is guaranteed by lopsided convergence, that was implemented computationally, obtaining numerical results for relevant examples. The second part, Essays about statistics and uncertainty modeling, contains two essays covering a convergence problem for a sequence

  14. Review Essay: "Personal Relations" as a Sociological Category?

    Directory of Open Access Journals (Sweden)

    Rainer Schützeichel

    2010-08-01

    Full Text Available This review essay discusses the question raised by the handbook "Personal Relations": whether and to what extent personal relations can be understood as a fundamental sociological category, one that is uniform and covers social relations such as pair relationships, brother-sister and parent-child relationships, family relations, friendships, neighbourhoods or informal working groups. It examines the different criteria which—according to the publishers—plead for establishing personal relations as a joint structural form. However, it also considers further aspects, such as the ways in which these forms of personal relations differ from other social relations, and raises the question of whether these differences can only be reconstructed through the means of an a-historical, systematic comparison of social relations—as suggested by the handbook. URN: urn:nbn:de:0114-fqs1003187

  15. On Emotions, Knowledge and Educational Institutions: An Explorative Essay

    Directory of Open Access Journals (Sweden)

    Thomas Karlsohn

    2016-06-01

    Full Text Available In this essay I formulate some reflections around the theme feelings and education.1 I will outline some essential features of the research and will argue that a historical approach to the subject will contribute by adding nuance to and complementing the often one-sided and misleading discussions that have marked the debate both within and outside of academia. In a subsequent part of the text I will concretise my reasoning by discussing one specific phenomenon from the past. I have chosen the example of love and will discuss the function it serves in higher education. The focus of the discussion will alternate between the Swedish context and international perspectives.

  16. The Weinberg-Witten theorem on massless particles: an essay

    International Nuclear Information System (INIS)

    Loebbert, F.

    2008-01-01

    In this essay we deal with the Weinberg-Witten theorem which imposes limitations on massless particles. First we motivate a classification of massless particles given by the Poincare group as the symmetry group of Minkowski spacetime. We then use the fundamental structure of the background in the form of Poincare covariance to derive restrictions on charged massless particles known as the Weinberg-Witten theorem. We address possible misunderstandings in the proof of this theorem motivated by several papers on this topic. In the last section the consequences of the theorem are discussed. We treat it in the context of known particles and as a constraint for emergent theories. (Abstract Copyright [2008], Wiley Periodicals, Inc.)

  17. Common findings and pseudolesions at computed tomography colonography: pictorial essay

    International Nuclear Information System (INIS)

    Atzingen, Augusto Castelli von; Tiferes, Dario Ariel; Matsumoto, Carlos Alberto; Nunes, Thiago Franchi; Maia, Marcos Vinicius Alvim Soares; D'Ippolito, Giuseppe

    2012-01-01

    Computed tomography colonography is a minimally invasive method for screening for polyps and colorectal cancer, with extremely unusual complications, increasingly used in the clinical practice. In the last decade, developments in bowel preparation, imaging, and in the training of investigators have determined a significant increase in the method sensitivity. Images interpretation is accomplished through a combined analysis of two-dimensional source images and several types of three-dimensional renderings, with sensitivity around 96% in the detection of lesions with dimensions equal or greater than 10 mm in size, when analyzed by experienced radiologists. The present pictorial essay includes examples of diseases and pseudolesions most frequently observed in this type of imaging study. The authors present examples of flat and polypoid lesions, benign and malignant lesions, diverticular disease of the colon, among other conditions, as well as pseudolesions, including those related to inappropriate bowel preparation and misinterpretation. (author)

  18. Review Essay: Grenzgänger Seeks Reflexive Methodology

    Directory of Open Access Journals (Sweden)

    Wolff-Michael Roth

    2002-09-01

    Full Text Available Reflexive Methodology reviews major strands of current thought in epistemology, philosophy, social science, and interpretive methods. The book falls short in that it neither does a thorough job reviewing the literature nor does it provide method-related advice useful to students. Grenzgängerin constitutes a collection of essays on a broad range of topics, but which are only loosely connected if at all. Drawing on DERRIDA and the notion of a historical science of the historical subject, I attempt to practice method, something I missed in both texts. I make explicit the historical nature of my own writing and the historical nature of my subject. I make explicit intertextuality and in the process practice reflexivity in the particular way I am writing. URN: urn:nbn:de:0114-fqs020328

  19. An Essay on Project Management in Organisational Change

    DEFF Research Database (Denmark)

    Ry Nielsen, Jens Carl; Ry, Morten

    2003-01-01

    ,indicating what we are not dealing with. We prefer to make a positive delineation, emphasisingwhat we are going to take up in our essay.Positively phrased we are inspired by 3 sources that will make the foundation for our differentangles:1. Decision making theory (Enderud,1976)4. One of the authors has previously...... with successapplied decision-making theory as an approach for analysing organisation change processes5. Both authors have followed the same line in analysing organisational changes inthe Danish public sector6. That success has inspired us to re-use the distinction betweenrational, political and anarchic processes...... differentangles, although not forgetting the sources you used. The implication of this is that we are not ableor willing to make an encompassing study of the literature on project management3. We thus knowthat many angles will not be covered. Furthermore we do not intend a make a negative delineation...

  20. Hierarchical decision modeling essays in honor of Dundar F. Kocaoglu

    CERN Document Server

    2016-01-01

    This volume, developed in honor of Dr. Dundar F. Kocaoglu, aims to demonstrate the applications of the Hierarchical Decision Model (HDM) in different sectors and its capacity in decision analysis. It is comprised of essays from noted scholars, academics and researchers of engineering and technology management around the world. This book is organized into four parts: Technology Assessment, Strategic Planning, National Technology Planning and Decision Making Tools. Dr. Dundar F. Kocaoglu is one of the pioneers of multiple decision models using hierarchies, and creator of the HDM in decision analysis. HDM is a mission-oriented method for evaluation and/or selection among alternatives. A wide range of alternatives can be considered, including but not limited to, different technologies, projects, markets, jobs, products, cities to live in, houses to buy, apartments to rent, and schools to attend. Dr. Kocaoglu’s approach has been adopted for decision problems in many industrial sectors, including electronics rese...

  1. Discrete thoughts essays on mathematics, science, and philosophy

    CERN Document Server

    Kac, Mark; Schwartz, Jacob T

    1992-01-01

    This is a volume of essays and reviews that delightfully explore mathematics in all its moods — from the light and the witty, and humorous to serious, rational, and cerebral. Topics include: logic, combinatorics, statistics, economics, artificial intelligence, computer science, and applications of mathematics broadly. You will also find history and philosophy covered, including discussion of the work of Ulam, Kant, Heidegger among others. "...these papers reflect on mathematics and its influence on human society. They can help the specialist to notice what is going on around him, and they may lead educated people from other domains to a better understanding of mathematics. Many of these papers can advise educators how to form a modern mathematics education, which develops approved ideas and institutions...I admire the stimulating perspectives of the authors."---American Mathematical Society "‘Mathematicians, like Proust and everyone else, are at their best when writing about their first love’ … They a...

  2. Short Essay on Managing Multicultural Students Groups within Diversity Context

    Directory of Open Access Journals (Sweden)

    Cătălin Ploae

    2016-01-01

    Full Text Available The present essay focuses on summarizing the key elements that should be considered wheneducators are in a position to manage and interact with a group of students from different culturesor social environments. In this respect, we consider that the challenge educators’ face inconnecting with students of diverse backgrounds is to develop a critical consciousness of the waysin which these larger discourses operate in their classrooms and to care enough to question them,to challenge them and to advocate for their students. To care for students who come fromhistorically marginalized populations educators need to remember that schooling can serve eithera liberating or marginalizing function. They can empower students to identify structures in societythat have contributed to marginalizing their perspective and seek to maintain inequitable structuresin society or even narrow communities.

  3. Imagination and rigor essays on Eduardo R Caianiello's scientific heritage

    CERN Document Server

    Termini, Settimo

    2006-01-01

    The aim of this Volume of scientific essays is twofold. From one side, by remembering the scientific figure of Eduardo R. Caianiello, it aims at focusing his outstanding contributions - from theoretical physics to cybernetics - which after so many years still represent occasion of innovative paths to be fruitfully followed. It must be stressed the contribution that his interdisciplinary methodology can still be of great help in affording and solving present day complex problems. On the other side, it aims at pinpointing with the help of the scientists contributing to the Volume - some crucial problems in present day research in the fields of interest of Eduardo Caianiello and which are still among the main lines of investigation of some of the Istitutes founded by Eduardo (Istituto di Cibernetica del CNR, IIAS, etc).

  4. Common findings and pseudolesions at computed tomography colonography: pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Atzingen, Augusto Castelli von [Clinical Radiology, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil); Tiferes, Dario Ariel; Matsumoto, Carlos Alberto; Nunes, Thiago Franchi; Maia, Marcos Vinicius Alvim Soares [Abdominal Imaging Section, Department of Imaging Diagnosis - Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil); D' Ippolito, Giuseppe, E-mail: giuseppe_dr@uol.com.br [Department of Imaging Diagnosis, Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil)

    2012-05-15

    Computed tomography colonography is a minimally invasive method for screening for polyps and colorectal cancer, with extremely unusual complications, increasingly used in the clinical practice. In the last decade, developments in bowel preparation, imaging, and in the training of investigators have determined a significant increase in the method sensitivity. Images interpretation is accomplished through a combined analysis of two-dimensional source images and several types of three-dimensional renderings, with sensitivity around 96% in the detection of lesions with dimensions equal or greater than 10 mm in size, when analyzed by experienced radiologists. The present pictorial essay includes examples of diseases and pseudolesions most frequently observed in this type of imaging study. The authors present examples of flat and polypoid lesions, benign and malignant lesions, diverticular disease of the colon, among other conditions, as well as pseudolesions, including those related to inappropriate bowel preparation and misinterpretation. (author)

  5. The Effects of Browse Time on the Internet on Students' Essay Scores

    Science.gov (United States)

    Doan, Kim; Bloomfield, Aaron

    2014-01-01

    This study examined how 30 minutes of search time on the Web affected students' essay scores in response to a writing prompt. Expository essays were obtained from 49 fourth- and fifth-grade students enrolled in an elementary school in Virginia, in the United States. Students were placed by random assignment into three groups with the same writing…

  6. Team Dynamics. Essays in the Sociology and Social Psychology of Sport Including Methodological and Epistemological Issues.

    Science.gov (United States)

    Lenk, Hans

    This document contains nine essays on the sociology and social psychology of team dynamics, including methodological and epistemological issues involved in such study. Essay titles are: (1) Conflict and Achievement in Top Athletic Teams--Sociometric Structures of Racing Eight Oar Crews; (2) Top Performance Despite Internal Conflict--An Antithesis…

  7. Essays on Crowdfunding: Exploring the Funding and Post-Funding Phases and Outcomes

    Science.gov (United States)

    Fan-Osuala, Onochie

    2017-01-01

    In the recent years, crowdfunding (a phenomenon where individuals collectively contribute money to back different goals and projects through the internet) has been gaining a lot of attention especially for its socio-economic impact. This dissertation explores this phenomenon in three distinct but related essays. The first essay explores the nature…

  8. Comparing Postsecondary Marketing Student Performance on Computer-Based and Handwritten Essay Tests

    Science.gov (United States)

    Truell, Allen D.; Alexander, Melody W.; Davis, Rodney E.

    2004-01-01

    The purpose of this study was to determine if there were differences in postsecondary marketing student performance on essay tests based on test format (i.e., computer-based or handwritten). Specifically, the variables of performance, test completion time, and gender were explored for differences based on essay test format. Results of the study…

  9. Topical Structure in Argumentative Essays of EFL Learners and Implications for Writing Classes

    Science.gov (United States)

    Kiliç, Mehmet; Genç, Bilal; Bada, Erdogan

    2016-01-01

    The literature on the topical organization of essays suggests that there are four possible types of progression from the topic of one clause to the topics of the following clauses. These are parallel, sequential, extended parallel, and extended sequential progressions. Essay writers' ability to create cohesion and coherence can be evaluated on the…

  10. Argument-Counterargument Structure in Indonesian EFL Learners' English Argumentative Essays: A Dialogic Concept of Writing

    Science.gov (United States)

    Rusfandi

    2015-01-01

    This study investigates the potential use of the argument-counterargument structure in English L2 essays written by Indonesian EFL learners. It examines whether L2 proficiency affects the use of opposing views in their essays, and measures whether there is a correlation between the use of the rhetorical structure and the participants' overall…

  11. Lexical Cohesion in Students' Argumentative Essay among a Select Group of Filipino College Students

    Science.gov (United States)

    Alarcon, Josephine B.

    2013-01-01

    This study analyzed the lexical devices used by undergraduate students in their argumentative text using Halliday and Hasan (1976) and Halliday's (2004) taxonomy. One hundred forty-eight argumentative essays were analyzed. The essays underwent interrating by three independent raters using a 20-point rubric and were grouped according to rating.…

  12. Enhancing Argumentative Essay Writing of Fourth-Grade Students with Learning Disabilities

    Science.gov (United States)

    Deatline-Buchman, Andria; Jitendra, Asha K.

    2006-01-01

    A within-subject pretest-posttest comparison design was used to explore the effectiveness of a planning and writing intervention in improving the argumentative writing performance of five fourth-grade students with learning disabilities. Students were taught to collaboratively plan and revise their essays and independently write their essays using…

  13. Relations between scripted online peer feedback processes and quality of written argumentative essay

    NARCIS (Netherlands)

    Noroozi, Omid; Biemans, Harm; Mulder, Martin

    2016-01-01

    Teachers often complain about the quality of students' written essays in higher education. This study explores the relations between scripted online peer feedback processes and quality of written argumentative essay as they occur in an authentic learning situation with direct practical relevance.

  14. Automated Assessment of Non-Native Learner Essays: Investigating the Role of Linguistic Features

    Science.gov (United States)

    Vajjala, Sowmya

    2018-01-01

    Automatic essay scoring (AES) refers to the process of scoring free text responses to given prompts, considering human grader scores as the gold standard. Writing such essays is an essential component of many language and aptitude exams. Hence, AES became an active and established area of research, and there are many proprietary systems used in…

  15. Essays on the Impact of Social Media: Evidence from the Music Industry and the Stock Market

    Science.gov (United States)

    Chen, Hailiang

    2012-01-01

    As both individuals and businesses are starting to embrace social media, understanding the power and influence of social media becomes an important question. This dissertation aims to address this issue and study the impact of social media in different contexts. It consists of two essays. The first essay examines the effectiveness of social media…

  16. Computer-Automated Approach for Scoring Short Essays in an Introductory Statistics Course

    Science.gov (United States)

    Zimmerman, Whitney Alicia; Kang, Hyun Bin; Kim, Kyung; Gao, Mengzhao; Johnson, Glenn; Clariana, Roy; Zhang, Fan

    2018-01-01

    Over two semesters short essay prompts were developed for use with the Graphical Interface for Knowledge Structure (GIKS), an automated essay scoring system. Participants were students in an undergraduate-level online introductory statistics course. The GIKS compares students' writing samples with an expert's to produce keyword occurrence and…

  17. The Ph.D. in Education. Carnegie Essays on the Doctorate: Education.

    Science.gov (United States)

    Richardson, Virginia

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  18. Words and Responsibilities: Graduate Education and the Humanities. Carnegie Essays on the Doctorate: Humanities.

    Science.gov (United States)

    Stimpson, Catharine R.

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  19. The Mathematics Doctorate: A Time for Change? Carnegie Essays on the Doctorate: Mathematics.

    Science.gov (United States)

    Chan, Tony F.

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  20. The Carnegie Initiative on the Doctorate: The Case of Mathematics. Carnegie Essays on the Doctorate: Mathematics.

    Science.gov (United States)

    Bass, Hyman

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  1. The Ph.D. in English: Towards a New Consensus. Carnegie Essays on the Doctorate: English.

    Science.gov (United States)

    Graff, Gerald

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  2. Reflections on Doctoral Education in Chemistry. Carnegie Essays on the Doctorate: Chemistry.

    Science.gov (United States)

    Kwiram, Alvin L.

    The Carnegie Foundation commissioned a collection of essays as part of the Carnegie Initiative on the Doctorate (CID). Essays and essayists represent six disciplines that are part of the CID: chemistry, education, English, history, mathematics, and neuroscience. Intended to engender conversation about the conceptual foundation of doctoral…

  3. A Strategy for Detection of Inconsistency in Evaluation of Essay Type Answers

    Science.gov (United States)

    Shukla, Archana; Chaudhary, Banshi D.

    2014-01-01

    The quality of evaluation of essay type answer books involving multiple evaluators for courses with large number of enrollments is likely to be affected due to heterogeneity in experience, expertise and maturity of evaluators. In this paper, we present a strategy to detect anomalies in evaluation of essay type answers by multiple evaluators based…

  4. Using Automated Essay Scores as an Anchor When Equating Constructed Response Writing Tests

    Science.gov (United States)

    Almond, Russell G.

    2014-01-01

    Assessments consisting of only a few extended constructed response items (essays) are not typically equated using anchor test designs as there are typically too few essay prompts in each form to allow for meaningful equating. This article explores the idea that output from an automated scoring program designed to measure writing fluency (a common…

  5. The Determination of Children's Knowledge of Global Lunar Patterns from Online Essays Using Text Mining Analysis

    Science.gov (United States)

    Cheon, Jongpil; Lee, Sangno; Smith, Walter; Song, Jaeki; Kim, Yongjin

    2013-01-01

    The purpose of this study was to use text mining analysis of early adolescents' online essays to determine their knowledge of global lunar patterns. Australian and American students in grades five to seven wrote about global lunar patterns they had discovered by sharing observations with each other via the Internet. These essays were analyzed for…

  6. Essays on optimal hedging and investment strategies and on derivative pricing

    NARCIS (Netherlands)

    van den Goorbergh, R.W.J.

    2004-01-01

    This dissertation encompasses four essays on various topics within the field of finance. Chapter 1 presents an overview of the contributions of each essay. Chapter 2, titled Risk Aversion, Price Uncertainty, and Irreversible Investments, extends the theory of irreversible investment under

  7. Researching Race and Social Justice in Education: Essays in Honour of Barry Troyna.

    Science.gov (United States)

    Sikes, Pat, Ed.; Rizvi, Fazal, Ed.

    The essays in this book comprise a "festschrift", a group of essays, to commemorate Barry Troyna, who made an important contribution to thinking about race, racism, and research on social-justice issues in the school context. Much of his work was directed at showing that it was impossible to research questions of "race"…

  8. Passages to Literature: Essays on Teaching in Australia, Canada, England, the United States, and Wales.

    Science.gov (United States)

    Milner, Joseph O'Beirne, Ed.; Milner, Lucy Floyd Morcock, Ed.

    Representing Australia, Canada, England, the United States, and Wales, this collection of essays focuses on ways in which teachers can adapt classroom activities and modify writing assignments to encourage personal response and exploration of texts. Essays, their authors, and nationalities are as follows: (1) "The River and Its Banks:…

  9. ‘Everybody’s Doing It’ : Essays on trust, social norms and integration

    NARCIS (Netherlands)

    Smerdon, D.C.

    2017-01-01

    This thesis investigates three topics at the intersection of behavioural and development economics, using a combination of experiments, econometric analysis and mathematical theory. The essays are borne out of topical questions with important policy implications. The first essay seeks to answer why

  10. An Evaluation of the IntelliMetric[SM] Essay Scoring System

    Science.gov (United States)

    Rudner, Lawrence M.; Garcia, Veronica; Welch, Catherine

    2006-01-01

    This report provides a two-part evaluation of the IntelliMetric[SM] automated essay scoring system based on its performance scoring essays from the Analytic Writing Assessment of the Graduate Management Admission Test[TM] (GMAT[TM]). The IntelliMetric system performance is first compared to that of individual human raters, a Bayesian system…

  11. ReaderBench Learns Dutch: Building a Comprehensive Automated Essay Scoring System for Dutch Language

    NARCIS (Netherlands)

    Dascalu, Mihai; Westera, Wim; Ruseti, Stefan; Trausan-Matu, Stefan; Kurvers, Hub

    2018-01-01

    Automated Essay Scoring has gained a wider applicability and usage with the integration of advanced Natural Language Processing techniques which enabled in-depth analyses of discourse in order capture the specificities of written texts. In this paper, we introduce a novel Automatic Essay Scoring

  12. What Do Education Students Think about Their Ability to Write Essays?

    Science.gov (United States)

    Quintero, Gisela Consolación

    2018-01-01

    The present study reflects the results obtained from a diagnosis carried out with Education students concerning the writing of academic essays. The objective was to identify the perceptions that Comprehensive Education students have about their ability to write academic essays. A descriptive cross-sectional research study was conducted at a single…

  13. Academic Essay Writing as Imitative Problem Solving: Examples from Distance Learning

    Science.gov (United States)

    Robertson, Sydney Ian

    2014-01-01

    Students in tertiary education are often faced with the prospect of writing an essay on a topic they know nothing about in advance. In distance learning institutions, essays are a common method of assessment in the UK, and specified course texts remain the main sources of information the students have. How do students use a source text to…

  14. Corrections on Grammar, Sentence Variety and Developing Detail to Qualify Academic Essay of Indonesian Learners

    Science.gov (United States)

    Solikhah, Imroatus

    2017-01-01

    This experimental research examines: (1) significant differences of corrections on grammar, sentence variety and developing details on the quality of the essay by Indonesian learners; and (2) different effect of corrections on grammar, sentence variety, and developing details on the quality of the essay. Treatments for each were served as follows:…

  15. The Impact of Training Students How to Write Introductions for Academic Essays: An Exploratory, Longitudinal Study

    Science.gov (United States)

    Brown, Gavin T. L.; Marshall, Jennifer C.

    2012-01-01

    Successful academic writing requires strong command of the rhetorical moves that orient the reader to the theme and substantive material of an academic essay. Effective control of the introduction leads to better overall writing. The goal of this study was to devise and evaluate a pedagogy for teaching the writing of academic essay introductions.…

  16. An Analysis of the Language of Attribution in University Students' Academic Essays

    Science.gov (United States)

    Jabulani, Sibanda

    2014-01-01

    The study reports on challenges related to the use of the language of attribution in academic essay writing by Post-Graduate Certificate in Education (PGCE) students at Rhodes University, as a microcosm of similar challenges faced by university students elsewhere. The study content-analysed 150 essays written by 50 PGCE students taking the course…

  17. Bioremediation of polluted wasewaterwater influent: phiosphorus and nitrogen removal. Scientific Research and Essays

    DEFF Research Database (Denmark)

    Muchie, Mammo; Akpor, OB

    2010-01-01

    Akpor OB and Muchie M. (2010). Bioremediation of polluted wasewaterwater influent: phiosphorus and nitrogen removal. Scientific Research and Essays, Vol. 5(21), pp. 3222–3230......Akpor OB and Muchie M. (2010). Bioremediation of polluted wasewaterwater influent: phiosphorus and nitrogen removal. Scientific Research and Essays, Vol. 5(21), pp. 3222–3230...

  18. Consumption-based learning about brand quality : Essays on how private labels share and borrow reputation

    NARCIS (Netherlands)

    Szymanowski, M.G.

    2009-01-01

    CONSUMPTION-BASED LEARNING ABOUT BRAND QUALITY: ESSAYS ON HOW PRIVATE LABELS SHARE AND BORROW REPUTATION is a collection of essays exploring the process of consumer cross-brand learning in the context of brands belonging to retailers: the so-called private labels. Private labels have gradually grown

  19. Intracranial involvement in plasmacytomas and multiple myeloma: a pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Cerase, Alfonso; Gennari, Paola; Monti, Lucia; Venturi, Carlo [Azienda Ospedaliera Universitaria Senese, Unit of Diagnostic and Therapeutic Neuroradiology, and InterDepartmental Center of Nuclear Magnetic Resonance, Policlinico ' Santa Maria alle Scotte' , Siena (Italy); Tarantino, Annachiara; Muccio, Carmine Franco [Azienda Ospedaliera ' G. Rummo' , Unit of Neuroradiology, Department of Neurosciences, Benevento (Italy); Gozzetti, Alessandro [University of Siena, Unit of Hematology and Transplants, Policlinico ' Santa Maria alle Scotte' , Siena (Italy); Di Blasi, Arturo [Azienda Ospedaliera ' G. Rummo' , Unit of Pathology, Department of Oncology, Benevento (Italy)

    2008-08-15

    The purpose of this pictorial essay is to increase awareness of the clinical presentation, neuroradiological findings, treatment options, and neuroradiological follow-up of plasmacytomas and multiple myeloma with intracranial growth. This pictorial essay reviews the clinical features and neuroradiological findings in seven patients (four women, three men; age range at diagnosis 62-82 years) followed in two institutions. Six patients, one with IgG-{kappa} plasmacytoma, and five with IgG-{kappa}(n=3), IgG-{lambda}(n=1), and nonsecretory (n=1) multiple myeloma, had been seen over a period of 9 years in one institution, and the other patient with IgG-{kappa} plasmacytoma had been seen over a period of 3.5 years in the other. Intracranial involvement is rare, most frequently resulting from osseous lesions in the cranial vault, skull base, nose, or paranasal sinuses. Primary dural or leptomeningeal involvement is rarer. Some typical findings of a dural and/or osseous plasmacytoma include iso- to hyperdensity on CT scan, T1 equal to high signal intensity and T2 markedly hypointense signal on MRI, and high vascularity possibly documented on intraarterial digital subtraction angiography. However, the neuroradiological findings generally lack specificity, since they are generally no different from those of meningioma, metastasis, lymphoma, dural sarcoma, plasma cell granuloma, infectious meningitis, and leptomeningeal carcinomatosis. The spectrum of clinical and neuroradiological evaluation shows that intracranial involvement from plasmacytoma and multiple myeloma must be taken into account in the differential diagnosis of cranial osseous and meningeal disease. (orig.)

  20. A Flipped Writing Classroom: Effects on EFL Learners’ Argumentative Essays

    Directory of Open Access Journals (Sweden)

    Fatemeh Soltanpour

    2018-02-01

    Full Text Available According to the literature, flipped teaching is a relatively new pedagogical approach in which the typical activities of classroom lectures followed by homework in common teaching practice are reversed in order, and most often integrated or supplemented with some types of instructional materials, such as instructional videos or PowerPoint files. This experimental study, using a pre-test-treatment-posttest-delayed posttest design, was aimed at investigating the effect of flipped instruction on Iranian EFL learners’ quality of argumentative essays. The participants were 55 students, who were assigned to two groups: the flipped classroom (FC and the traditional classroom (TC. Each group received 3 sessions of treatment. First, whether there was any significant difference between the FC and TC in the overall quality of the essays was investigated. The FC group significantly outperformed the TC one. Then, whether the difference between the groups varied over time was explored, and it was revealed that the FC was still significantly superior over the TC. Next, whether there would be any significant change in the FC in the long run was examined, and no significant change was seen. The promising results found in FC group can be attributed to not only the flipped instruction but also the process of actively engaging the learners in their learning in addition to incorporating different techniques, such as the video screencasting, collaborative writing, as well as in-class teacher-learner interaction and negotiation because it is argued that the crucial point in flipped instruction is how teachers best use in-class-time with students.

  1. Chlorination disinfection by-products in drinking water and congenital anomalies: review and meta-analyses Subprodutos da desinfecção com cloro em água potável e anomalias congênitas: revisão e meta-análise

    Directory of Open Access Journals (Sweden)

    Mark J. Nieuwenhuijsen

    2010-10-01

    Full Text Available This study aims to review epidemiologic evidence of the association between exposure to chlorination disinfection by-products (DBPs and congenital anomalies. All epidemiologic studies that evaluated a relationship between an index of DBP exposure and risk of congenital anomalies were analyzed. For all congenital anomalies combined, the meta-analysis gave a statistically significant excess risk for high versus low exposure to water chlorination or TTHM (17%; 95% CI, 3-34 based on a small number of studies. The meta-analysis also suggested a statistically significant excess risk for ventricular septal defects (58%; 95% CI, 21-107, but based on only three studies, and there was little evidence of an exposure-response relationship. It was observed no statistically significant relationships in the other meta-analyses and little evidence for publication bias, except for urinary tract defects and cleft lip and palate. Although some individual studies have suggested an association between chlorination disinfection by-products and congenital anomalies, meta-analyses of all currently available studies demonstrate little evidence of such association.O objetivo deste estudo é revisar evidências epidemiológicas da associação entre a exposição a subprodutos da desinfecção com cloro (DBPs e anomalias congênitas. Todos os estudos epidemiológicos que avaliaram a relação entre o índice de exposição a DBPs e o risco de anomalias congênitas foram analisados. Para todas as anomalias congênitas combinadas, a meta-análise resultou em um risco de excesso estatisticamente significante para alta versus baixa exposição à cloração da água ou ao TTHM (17%; 95% CI, 3-34 baseado em um pequeno número de estudos. A meta-análise também sugere um excesso de risco estatisticamente significante para defeitos septais ventriculares (58%; 95% CI, 21-107, porém com base em apenas três estudos, nos quais se encontrou pouca evidência na relação exposi

  2. THE STRATEGY OF USING PERSUASIVE ESSAY IN ENGLISH FOR MEDICAL ACADEMIC WRITING

    Directory of Open Access Journals (Sweden)

    Ellie Setyo Wahyuni

    2014-06-01

    Full Text Available Writing persuasive essay has the purpose of providing some techniques in organizing the idea and constructing the sentences in coherence. The content of this essay contains the health issue and medical terms. The students of medical faculty are expected to make a good persuasive essay in order to find out the recommendation solution of a health problem through the strategies (1 brainstorming (2 mapping (3 the 5 W’s (4 setting thesis statement (5 providing fact, statistic, and example (5 conclusion. The techniques have improved the student writing as the essays have been evaluated and given positive input on the content and development of paragraphs. This academic writing aims to give some practices for the Medical Faculty students of Hang Tuah University in order to produce a good persuasive essay in term of coherence, sentence structure, and organization.

  3. Characteristics and distribution of dental anomalies in a Brazilian cleft population = Características e distribuição de anomalias dentárias em uma população brasileira de portadores de fissuras lábio-palatais

    Directory of Open Access Journals (Sweden)

    Menezes, Luciane Macedo de

    2010-01-01

    Full Text Available Objetivos: Determinar a prevalência de anomalias dentárias em 200 pacientes com fissura sob tratamento ortodôntico no Centro de Reabilitação Lábio-Palatal (CERLAP da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS. Metodologia: Os dados referentes à idade, raça, gênero, tipo de fissura (pré, trans ou pós-forame incisivo, lado afetado (uni ou bilateral, agenesias e supranumerários em ambas arcadas foram avaliados a partir da documentação ortodôntica constituída por radiografias panorâmicas, cefalométricas, oclusais e periapicais, modelos de estudo e fotografias intra e extrabucais obtidas no início do tratamento, fornecendo informações necessárias para diagnóstico de anomalias dentárias. Os dados coletados foram registrados em planilhas. Resultados: A média de idade dos pacientes foi de 13. 5 anos; 86% eram brancos; e 57% eram meninos. Fissuras transforame incisivo demonstraram-se mais frequentes (83%; o lado esquerdo foi mais afetado (48. 5%. Agenesias foram encontradas em 66. 5% dos pacientes. Incisivos laterais superiores foram os dentes mais ausentes (78. 5%. Supranumerários foram encontrados em 35. 5 % dos pacientes. Conclusão: Meninos demonstraram maior tendência a apresentar fissuras e a manifestar agenesias dentárias e supranumerários. As fissuras completas de lábio e palato prevaleceram e os incisivos laterais superiores foram os dentes mais ausentes. Os supranumerários localizaram-se distalmente à fissura na maioria dos casos

  4. Essays on the Determinants of Energy Related CO2 Emissions =

    Science.gov (United States)

    Moutinho, Victor Manuel Ferreira

    Overall, amongst the most mentioned factors for Greenhouse Gases (GHG) growth are the economic growth and the energy demand growth. To assess the determinants GHG emissions, this thesis proposed and developed a new analysis which links the emissions intensity to its main driving factors. In the first essay, we used the 'complete decomposition' technique to examine CO2 emissions intensity and its components, considering 36 economic sectors and the 1996-2009 periods in Portugal. The industry (in particular 5 industrial sectors) is contributing largely to the effects of variation of CO2 emissions intensity. We concluded, among others, the emissions intensity reacts more significantly to shocks in the weight of fossil fuels in total energy consumption compared to shocks in other variables. In the second essay, we conducted an analysis for 16 industrial sectors (Group A) and for the group of the 5 most polluting manufacturing sectors (Group B) based on the convergence examination for emissions intensity and its main drivers, as well as on an econometric analysis. We concluded that there is sigma convergence for all the effects with exception to the fossil fuel intensity, while gamma convergence was verified for all the effects, with exception of CO2 emissions by fossil fuel and fossil fuel intensity in Group B. From the econometric approach we concluded that the considered variables have a significant importance in explaining CO2 emissions and CO2 emissions intensity. In the third essay, the Tourism Industry in Portugal over 1996-2009 period was examined, specifically two groups of subsectors that affect the impacts on CO2 emissions intensity. The generalized variance decomposition and the impulse response functions pointed to sectors that affect tourism more directly, i. e. a bidirectional causality between the intensity of emissions and energy intensity. The effect of intensity of emissions is positive on energy intensity, and the effect of energy intensity on

  5. A Pilot Intervention to Improve the Structural Quality of Exam Essay Writing in UK Undergraduate Psychology Students

    Science.gov (United States)

    Connelly, Vincent; Dockrell, Julie E.; Barnett, Jo

    2006-01-01

    Psychology undergraduates need to produce good quality essays in order to succeed at university. Students find the transition to university writing difficult. Using a rubric, a profile of student weakness in psychology essay writing was described. The students were generally poor at the structural organisation of their essays. A pilot intervention…

  6. Three essays in transportation energy and environmental policy

    Science.gov (United States)

    Hajiamiri, Sara

    Concerns about climate change, dependence on oil, and unstable gasoline prices have led to significant efforts by policymakers to cut greenhouse gas (GHG) emissions and oil consumption. The transportation sector is one of the principle emitters of CO2 in the US. It accounts for two-thirds of total U.S. oil consumption and is almost entirely dependent on oil. Within the transportation sector, the light-duty vehicle (LDV) fleet is the main culprit. It is responsible for more than 65 percent of the oil used and for more than 60 percent of total GHG emissions. If a significant fraction of the LDV fleet is gradually replaced by more fuel-efficient technologies, meaningful reductions in GHG emissions and oil consumption will be achieved. This dissertation investigates the potential benefits and impacts of deploying more fuel-efficient vehicles in the LDV fleet. Findings can inform decisions surrounding the development and deployment of the next generation of LDVs. The first essay uses data on 2003 and 2006 model gasoline-powered passenger cars, light trucks and sport utility vehicles to investigate the implicit private cost of improving vehicle fuel efficiencies through reducing other desired attributes such as weight (that is valued for its perceived effect on personal safety) and horsepower. Breakeven gasoline prices that would justify the estimated implicit costs were also calculated. It is found that to justify higher fuel efficiency standards from a consumer perspective, either the external benefits need to be very large or technological advances will need to greatly reduce fuel efficiency costs. The second essay estimates the private benefits and societal impacts of electric vehicles. The findings from the analysis contribute to policy deliberations on how to incentivize the purchase and production of these vehicles. A spreadsheet model was developed to estimate the private benefits and societal impacts of purchasing and utilizing three electric vehicle

  7. Three Essays In and Tests of Theoretical Urban Economics

    Science.gov (United States)

    Zhao, Weihua

    This dissertation consists of three essays on urban economics. The three essays are related to urban spatial structure change, energy consumption, greenhouse gas emissions, and housing redevelopment. Chapter 1 answers the question: Does the classic Standard Urban Model still describe the growth of cities? Chapter 2 derives the implications of telework on urban spatial structure, energy consumption, and greenhouse gas emissions. Chapter 3 investigates the long run effects of minimum lot size zoning on neighborhood redevelopment. Chapter 1 identifies a new implication of the classic Standard Urban Model, the "unitary elasticity property (UEP)", which is the sum of the elasticity of central density and the elasticity of land area with respect to population change is approximately equal to unity. When this implication of the SUM is tested, it fits US cities fairly well. Further analysis demonstrates that topographic barriers and age of housing stock are the key factors explaining deviation from the UEP. Chapter 2 develops a numerical urban simulation model with households that are able to telework to investigate the urban form, congestion, energy consumption and greenhouse gas emission implications of telework. Simulation results suggest that by reducing transportation costs, telework causes sprawl, with associated longer commutes and consumption of larger homes, both of which increase energy consumption. Overall effects depend on who captures the gains from telework (workers versus firms), urban land use regulation such as height limits or greenbelts, and the fraction of workers participating in telework. The net effects of telework on energy use and GHG emissions are generally negligible. Chapter 3 applies dynamic programming to investigate the long run effects of minimum lot size zoning on neighborhood redevelopment. With numerical simulation, comparative dynamic results show that minimum lot size zoning can delay initial land conversion and slow down demolition and

  8. How to improve nuclear security worldwide: Three young women win IAEA essay contest

    International Nuclear Information System (INIS)

    Li, Jeremy

    2016-01-01

    Three essays that provided actionable and innovative recommendations to strengthen nuclear security through stronger border controls, closer international cooperation and public education won the IAEA’s first ever nuclear security essay contest. In preparation for the International Conference on Nuclear Security: Commitments and Actions, the IAEA invited students and young professionals to submit essays focusing on challenges and recommendations to strengthen nuclear security. A panel of experts from the IAEA and the International Nuclear Security Education Network selected three winners from among the 353 submissions received. The winners will present their papers at the conference, taking place in Vienna in December 2016

  9. How to improve nuclear security worldwide: Three young women win IAEA essay contest

    International Nuclear Information System (INIS)

    Li, Jeremy

    2016-01-01

    Three essays that provided actionable and innovative recommendations to strengthen nuclear security through stronger border controls, closer international cooperation and public education won the IAEA’s first ever nuclear security essay contest. In preparation for the International Conference on Nuclear Security: Commitments and Actions, the IAEA invited students and young professionals to submit essays focusing on challenges and recommendations to strengthen nuclear security. A panel of experts from the IAEA and the International Nuclear Security Education Network selected three winners from among the 353 submissions received. The winners will present their papers at the conference, taking place in Vienna in December 2016.

  10. Neuroimaging findings of congenital Zika virus infection: a pictorial essay.

    Science.gov (United States)

    Zare Mehrjardi, Mohammad; Poretti, Andrea; Huisman, Thierry A G M; Werner, Heron; Keshavarz, Elham; Araujo Júnior, Edward

    2017-03-01

    Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family. It had caused several epidemics since its discovery in 1947, but there was no significant attention to this virus until the recent outbreak in Brazil in 2015. The main concern is the causal relationship between prenatal ZIKV infection and congenital microcephaly, which has been confirmed recently. Moreover, ZIKV may cause other central nervous system abnormalities such as brain parenchymal atrophy with secondary ventriculomegaly, intracranial calcification, malformations of cortical development (such as polymicrogyria, and lissencephaly-pachygyria), agenesis/hypoplasia of the corpus callosum, cerebellar and brainstem hypoplasia, sensorineural hearing-loss, and ocular abnormalities as well as arthrogryposis in the infected fetuses. Postnatal (acquired) ZIKV infection usually has an asymptomatic or mildly symptomatic course, while prenatal (congenital) ZIKV infection has a more severe course and may cause severe brain anomalies that are described as congenital Zika syndrome. In this pictorial essay, we aim to illustrate the prenatal and postnatal neuroimaging findings that may be seen in fetuses and neonates with congenital Zika syndrome, and will discuss possible radiological differential diagnoses. A detailed knowledge of these findings is paramount for an early correct diagnosis, prognosis determination, and counseling of the affected children and families.

  11. Magnetic resonance imaging of the growth plate: pictorial essay

    International Nuclear Information System (INIS)

    Cairns, R.

    2003-01-01

    The approach to musculoskeletal magnetic resonance imaging (MRI) is very different in children than adults because of different disease processes, immature structures and the variable size and age of the patients. Use of routine adult musculoskeletal protocols and techniques may not provide sufficient information in children, and most pediatric examinations should be customized to specifically address the child's age and clinical problem. This pictorial essay will illustrate MRI of the growth plate - often an area of uncertainty or error for radiologists who infrequently perform musculoskeletal MRI on children. The growth plate or physis is a structure unique to the growing skeleton. It is a cartilaginous zone located between the epiphysis and the metaphysis that functions to provide longitudinal bone growth. Disturbance of physeal growth as a result of trauma, infection, tumour, ischemia or radiation can result in leg length discrepancy, angular deformity or altered joint mechanics and cause significant long-term disability. MRI can directly image cartilaginous structures and has thus become the imaging method of choice for evaluation of the growth plate. An understanding of the normal and abnormal appearance of growth cartilage and of MRI protocols optimized for imaging the growth plate, combined with an approach to risk assessment for the development of significant growth deformity, is needed to confidently image the growth plate and help direct the management of these patients. (author)

  12. Review Essay: Situational Analysis—Strauss Meets Foucault?

    Directory of Open Access Journals (Sweden)

    Rainer Diaz-Bone

    2012-11-01

    Full Text Available With the (German translation of the volume "Situational Analysis" by Adele CLARKE, a new approach to the development of Grounded Theory Methodology (GTM is presented. CLARKE radicalizes the methodological standpoint of classical pragmatism. She integrates structuralist and post-structuralist analytic elements into GTM. This review essay critically analyzes this new integration and employs the methodological notion of the "theory/methods package" introduced by CLARKE, which denotes the cohesion of theory, methodology and methods, and can be conceived as a kind of “methodic holism” (not to be confused with the different concept of methodological holism. CLARKE puts more emphasis on objects and power than classical GTM, and attempts to integrate a FOUCAULTian discourse model. However, she does not succeed in integrating the pragmatic and structuralist/post-structuralist methodologies in a fully coherent way. Her situational analysis does not incorporate a discourse-analytic methodology, and has not implemented the methods needed for a FOUCAULTian discourse analysis. Nevertheless, this valuable work presents an important development in pragmatic social research. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1301115

  13. Reading and Theorizing James Baldwin: A Bibliographic Essay

    Directory of Open Access Journals (Sweden)

    Conseula Francis

    2015-09-01

    Full Text Available Readers and critics alike, for the past sixty years, generally agree that Baldwin is a major African-American writer. What they do not agree on is why. Because of his artistic and intellectual complexity, Baldwin’s work resists easy categorization and Baldwin scholarship, consequently, spans the critical horizon. This essay provides an overview of the three major periods of Baldwin scholarship. 1963–73 is a period that begins with the publication of The Fire Next Time and sees Baldwin grace the cover of Time magazine. This period ends with Time declaring Baldwin too passé to publish an interview with him and with critics questioning his relevance. The second period, 1974–87, finds critics attempting to rehabilitate Baldwin’s reputation and work, especially as scholars begin to codify the African-American literary canon in anthologies and American universities. Finally, scholarship in the period after Baldwin’s death takes the opportunity to challenge common assumptions and silences surrounding Baldwin’s work. Armed with the methodologies of cultural studies and the critical insights of queer theory, critics set the stage for the current Baldwin renaissance.

  14. Computed tomographic features of afferent loop syndrome: pictorial essay

    Energy Technology Data Exchange (ETDEWEB)

    Zissin, R. [Tel-Aviv Univ., Dept. of Diagnostic Imaging, Sapir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv (Israel); Hertz, M. [Tel-Aviv Univ., Dept. of Diagnostic Imaging, Chaim Sheba Medical Center, Tel Hashomer, Tel Aviv (Israel); Paran, H. [Tel-Aviv Univ., Dept. of Diagnostic Imaging, Surgery ' A' , Sapir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv (Israel); Osadchy, A. [Tel-Aviv Univ., Dept. of Diagnostic Imaging, Sapir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv (Israel); Gayer, G. [Tel-Aviv Univ., Dept. of Diagnostic Imaging, Assaf Harofe Medical Center, Zrifin, Sackler Faculty of Medicine, Tel Aviv (Israel)

    2005-04-15

    This pictorial essay reviews the computed tomography (CT) findings of afferent loop syndrome (ALS) in various pathological conditions to demonstrate the contribution of a common imaging modality-that is, abdominal CT, used nowadays for various abdominal complaints-to the diagnosis of ALS. ALS is caused by obstruction of the duodenum and jejunum proximal to a gastrojejunostomy anastomosis. It is a rare complication after Billroth II subtotal gastrectomy and even more rare after total or subtotal gastrectomy with Roux-en-Y reconstruction. Although currently advanced medical treatment and endoscopic interventions have dramatically decreased the necessity of surgery for peptic ulcer disease, ALS may appear years after previously common operations. Alternatively, the use of surgical resection for early gastric cancer nowadays leads to an increasing rate of malignancy-related ALS. Clinically, ALS may be difficult to diagnose as its presentation may be vague and nonspecific, but it has a characteristic appearance on CT. Clinicians and radiologists should therefore be familiar with this rare complication. Prompt recognition and correct diagnosis of this syndrome and its probable etiology are important as a guide for treatment. This review illustrates the CT features of ALS in various conditions. (author)

  15. The mythical man-month essays on software engineering

    CERN Document Server

    Brooks, Frederick Phillips

    1995-01-01

    Few books on software project management have been as influential and timeless as The Mythical Man-Month. With a blend of software engineering facts and thought-provoking opinions, Fred Brooks offers insight for anyone managing complex projects. These essays draw from his experience as project manager for the IBM System/360 computer family and then for OS/360, its massive software system. Now, 20 years after the initial publication of his book, Brooks has revisited his original ideas and added new thoughts and advice, both for readers already familiar with his work and for readers discovering it for the first time. The added chapters contain (1) a crisp condensation of all the propositions asserted in the original book, including Brooks' central argument in The Mythical Man-Month: that large programming projects suffer management problems different from small ones due to the division of labor; that the conceptual integrity of the product is therefore critical; and that it is difficult but possible to achi...

  16. PROBLEMS FACED BY INDONESIAN EFL LEARNERS IN WRITING ARGUMENTATIVE ESSAY

    Directory of Open Access Journals (Sweden)

    Wulan Rahmatunisa

    2014-12-01

    Full Text Available This study aims to find out problems in writing argumentative essay faced by Indonesian EFL learners. It is carried out in a qualitative research design as it attempted to describe the problems and their ways out. The data were taken from university students’ writing task and interview. The participants are the second year of university Indonesia students who enrol their study in English Department. Results of the data indicated that Indonesian EFL learners faced the problems in three categories, those are linguistics problems, cognitive problems, and psychological problems. Mostly, students faced problems in linguistics related to the grammatical structure (23.2%, formatting words (30.2%, words classes (16.3%, error in using words (9.3%, and the use of article (21%. Second, cognitive problems are related to organizing paragraph, difficulties in remaining word classes, getting lost the generic structure, making a conclusion, and putting punctuation. Last, psychological problems which included laziness, egoism, bad mood, and difficulties to start writing also faced by Indonesian EFL learners. Data analysis also indicated the problem solving which hopefully will be beneficial for EFL teachers in writing class. It is strongly recommended that the EFL class should strengthen all the language skills in general and writing in particular, motivate the students to use English with the teachers, introduce pair work, peer-correction, and use dictionaries frequently etc.

  17. Computed tomography of intra - and extramural ethmoid cells: iconographic essay

    International Nuclear Information System (INIS)

    Goncalves, Fabricio Guimaraes; Moura, Leonardo de Oliveira

    2011-01-01

    The development of the paranasal sinuses is an intricate process that begins in the intrauterine life and terminates in early adulthood. Among the paranasal sinuses, the ethmoid cells or labyrinth are probably the most complex structures, being associated with the highest number of normal variants. Variations in the pattern of pneumatization of the ethmoid cells can be divided into intra - and extramural cells. Intramural cells are those which develop within the ethmoid labyrinth. Extramural cells are those that develop isolatedly. Computed tomography is the most useful tool in the evaluation of inflammatory processes of the paranasal sinuses. Computed tomography also plays a relevant role in the preoperative planning as well as in the postoperative follow-up, since it demonstrates exact anatomical details of normal structures with accuracy in the detection of variants. In the present pictorial essay, the authors describe the most common anatomical variants of the ethmoid labyrinth and their relationship with adjacent structures. Endoscopic sinonasal surgery has become increasingly less invasive, requiring more detailed anatomical imaging of this region. (author)

  18. Pictorial essay: Vascular interventions in extra cranial head and neck

    Directory of Open Access Journals (Sweden)

    Suyash S Kulkarni

    2012-01-01

    Full Text Available Medicine is an ever changing field and interventional radiology (IR procedures are becoming increasingly popular because of high efficacy and its minimally invasive nature of the procedure. Management of disease processes in the extra cranial head and neck (ECHN has always been a challenge due to the complex anatomy of the region. Cross sectional imaging of the ECHN has grown and evolved tremendously and occupies a pivotal and integral position in the clinical management of variety of head and neck pathologies. Advances in angiographic technologies including flat panel detector systems, biplane, and 3-dimensional rotational angiography have consolidated and expanded the role of IR in the management of various ECHN pathologies. The ECHN is at cross roads between the origins of great vessels and the cerebral vasculature. Thorough knowledge of functional and technical aspects of neuroangiography is essential before embarking on head and neck vascular interventions. The vessels of the head and neck can be involved by infectious and inflammatory conditions, get irradiated during radiotherapy and injured due to trauma or iatrogenic cause. The ECHN is also a common site for various hypervascular neoplasms and vascular malformations, which can be treated with endovascular and percutaneous embolization. This pictorial essay provides a review of variety of ECHN pathologies which were managed by various IR procedures using different approaches.

  19. ESSAY ON THE EFFECTIVENESS OF THE COLLECTIVE PROTECTION IN PORTUGAL

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    Luciano Picoli Gagno

    2017-08-01

    Full Text Available This essay aims to examine certain aspects concerning collective judicial process by the light of some Portuguese cases, having as base the collective judicial protection understood as a fundamental right. With regard to the employed research method, the approach is the qualitative one, while the method is the deductive and the technique is the bibliographic e jurisprudential research. The theoretical framework is based on the doctrine and theory of some of the cited authors during the research. Among them are Robert Alexy, Mauro Cappelletti and Bryant Garth. In addition, this paper is divided into three sections: the first one is a brief study on access to justice clarified as a fundamental right of the citizen. In the second section a parallel is made with the first one, but the collective judicial protection is therefore seen as a fundamental right. In the third and last section we have the analysis of four cases of two superior courts of Portugal, being them the Supreme Court of Justice (STJ and the Supreme Administrative Court (STA, in order to understand the collective process in Portugal and to see which points that can offer a contribution for the brazilian collective procedural technic. As a result, it is found that collective judicial protection is inevitable and immanent for a substantial vision of the fundamental right of access to justice, understood like a orders of optimization, that may his realization in the biggest measure is possible

  20. Essays in the history of Lie groups and algebraic groups

    CERN Document Server

    Borel, Armand

    2001-01-01

    Lie groups and algebraic groups are important in many major areas of mathematics and mathematical physics. We find them in diverse roles, notably as groups of automorphisms of geometric structures, as symmetries of differential systems, or as basic tools in the theory of automorphic forms. The author looks at their development, highlighting the evolution from the almost purely local theory at the start to the global theory that we know today. Starting from Lie's theory of local analytic transformation groups and early work on Lie algebras, he follows the process of globalization in its two main frameworks: differential geometry and topology on one hand, algebraic geometry on the other. Chapters II to IV are devoted to the former, Chapters V to VIII, to the latter. The essays in the first part of the book survey various proofs of the full reducibility of linear representations of \\mathbf{SL}_2{(\\mathbb{C})}, the contributions of H. Weyl to representations and invariant theory for semisimple Lie groups, and con...

  1. Fertility in the Age of Demographic Maturity: An Essay

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    Anatole Romaniuk

    2010-01-01

    Full Text Available As humanity is moving into a new age of its demographic evolution, I call it demographic maturity, the emerging demographic configurations – generational sub-replacement fertility, advanced aging and potential population implosion – call for new ways of thinking about population and new policy approaches. While we live longer and healthier, we also reproduce less and less. We are stuck in a culture of low fertility. The strong motivations for foregoing motherhood are financial: a two-salary wage is better than one even for the higher middle class. No less important is the woman’s financial independence in a societal environment where marriage as an institution is under considerable stress. Motherhood is to be rewarded adequately for its highly important social role and it has to be sufficient to reassure potential mothers of their financial concerns. What is required is a more balanced resource allocation between production and reproduction. The old welfare type hand-outs like child bonuses do not work. Societies, particularly the rich, ought to realize that to raise fertility, even to generational replacement level, not only is a much greater financial effort called for but some of the tenants of the liberal economy need to be put into question to make room for social concerns such a renewal of generations, if they want to survive as national entities. This essay advocates a stationary population as the best response to challenges such as ecological health, national identity and cohesion, and possibly world peace.

  2. Fertility in the Age of Demographic Maturity: An Essay

    Directory of Open Access Journals (Sweden)

    Anatole Romaniuk

    2010-12-01

    wage is better than one even for the higher middle class. No less important is the woman’s financial independence in a societal environment where marriage as an institution is under considerable stress. Motherhood is to be rewarded adequately for its highly important social role and it has to be sufficient to reassure potential mothers of their financial concerns. What is required is a more balanced resource allocation between production and reproduction. The old welfare type hand-outs like child bonuses do not work. Societies, particularly the rich, ought to realize that to raise fertility, even to generational replacement level, not only is a much greater financial effort called for but some of the tenants of the liberal economy need to be put into question to make room for social concerns such a renewal of generations, if they want to survive as national entities. This essay advocates a stationary population as the best response to challenges such as ecological health, national identity and cohesion, and possibly world peace.

  3. Can that be right? essays on experiment, evidence, and science

    CERN Document Server

    Franklin, Allan

    1999-01-01

    In this collection of essays Allan Franklin defends the view that science provides us with knowledge about the world which is based on experimental evidence and on reasoned and critical discussion. In short, he argues that science is a reasonable enterprise. He begins with detailed studies of four episodes from the history of modern physics: (1) the early attempts to detect gravity waves, (2) how the physics community decided that a proposed new elementary particle, 17-keV neutrino, did not exist, (3) a sequence of experiments on K meson decay, and (4) the origins of the Fifth Force hypothesis, a proposed modification of Newton's Law of Universal Gravitation. The case studies are then used to examine issues such as how discord between experimental results is resolved, calibration of an experimental apparatus and its legitimate use in validating an experimental result, and how experimental results provide reasonable grounds for belief in both the truth of physical theories and in the existence of the entities ...

  4. Three essays on productivity and risk, marketing decisions, and changes in well-being over time

    OpenAIRE

    Larochelle, Catherine

    2011-01-01

    This dissertation is composed of three essays; the first two examine the decision-making of potato producing households in Bolivia and the third examines well-being changes among Zimbabwe households. The first essay entitled â The role of risk mitigation in production efficiency: A case study of potato cultivation in the Bolivian Andesâ estimates the costs of self-managing environmental risk through activity and environmental diversification. Risk management has the potential to reduce in...

  5. Our 9/11 of hope: Short essays on European democracy since 1989

    OpenAIRE

    Tassinari, Fabrizio

    2010-01-01

    This collection of short essays proceeds from an international conference organized by DIIS on 9th November 2009, the day of the twentieth anniversary of the fall of the Berlin Wall. The volume centers on the political, social, and economic implications of the revolutions of 1989 on European democracy. The authors of these essays come from very different backgrounds and interests: ranging from academics and public intellectuals that have written extensively on post-Cold War Europe, to practit...

  6. Use of X-ray essay and fluoroscopy in the armament industry

    International Nuclear Information System (INIS)

    Bohnsack, G.

    1989-01-01

    Of the nondestructive testing the process of test by radiography has a special place. With view to great variety of problems of essays in the armament industry, the X-Ray radiography has excellent possibilities of testing, that not possible, for example, with ultrasonography. Different possibilities that the X-ray radiography offer to essays of grenade and blasting cap, through practice examples described case to case are presented. (V.R.B.)

  7. Essays on the effects of human capital, innovation and technology on economic performance

    OpenAIRE

    Tiruneh, Esubalew Alehegn

    2014-01-01

    This thesis is on human capital (HC) and innovation in Germany and comprises of three essays. The first essay provides a comparative analysis on the economic performance impacts of creative class and HC at regional level with the purpose of testing whether the contemporary occupation-based creative class or the conventional education-based HC can be used as a better driver of regional economy. In doing so, I disaggregate creative class into creative core (scientific experts), creative profess...

  8. Essays on household time allocation decisions in a collective household model

    OpenAIRE

    Silvennoinen, Heidi

    2008-01-01

    This thesis considers the consequences of traditional division of labour in households in a setting where spouses are allowed to have distinct preferences. This approach leads to different results compared to the traditional unitary approach and is better equipped to take into consideration gender related issues of household decision making. The thesis consists of three theoretical essays where the household production theory is applied in the collective household model. The first essay ...

  9. The use of an essay examination in evaluating medical students during the surgical clerkship.

    Science.gov (United States)

    Smart, Blair J; Rinewalt, Daniel; Daly, Shaun C; Janssen, Imke; Luu, Minh B; Myers, Jonathan A

    2016-01-01

    Third-year medical students are graded according to subjective performance evaluations and standardized tests written by the National Board of Medical Examiners (NBME). Many "poor" standardized test takers believe the heavily weighted NBME does not evaluate their true fund of knowledge and would prefer a more open-ended forum to display their individualized learning experiences. Our study examined the use of an essay examination as part of the surgical clerkship evaluation. We retrospectively examined the final surgical clerkship grades of 781 consecutive medical students enrolled in a large urban academic medical center from 2005 to 2011. We examined final grades with and without the inclusion of the essay examination for all students using a paired t test and then sought any relationship between the essay and NBME using Pearson correlations. Final average with and without the essay examination was 72.2% vs 71.3% (P essay examination increasing average scores by .4, 1.8, and 2.5 for those receiving high pass, pass, and fail, respectively. The essay decreased the average score for those earning an honors by .4. Essay scores were found to overall positively correlate with the NBME (r = .32, P essay examination as part of the third-year surgical core clerkship final did increase the final grade a modest degree, especially for those with lower scores who may identify themselves as "poor" standardized test takers. A more open-ended forum may allow these students an opportunity to overcome this deficiency and reveal their true fund of surgical knowledge. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Aesthetic Function Realized in the Selected Modern Chinese Essays by Zhang Peiji

    Institute of Scientific and Technical Information of China (English)

    罗丹

    2014-01-01

    The selected modern Chinese essays translated by Zhang Peiji is a masterpiece for Chinese scholars to do translation research. Prof. Zhang not only excels at translating the Chinese works accurately but also conveys the aesthetic value in the translated version. This paper wil analyse the aesthetic function used in Zhang Peiji’s selected modern Chinese essays from five aspects, music value, rhythm value, ful-grownness value, conciseness value and artistic conception value.

  11. Anomalias ósseas congênitas em Sotalia guianensis (Mammalia, Cetacea, Delphinidae da costa centro-norte do Estado do Rio de Janeiro Congenital bone defects in Guiana dolphin, Sotalia guianensis (Mammalia, Cetacea, Delphinidae in the northcentral coast of Rio de Janeiro State, Brazil

    Directory of Open Access Journals (Sweden)

    Maíra Laeta

    2010-06-01

    Full Text Available Carcaças de botos-cinza Sotalia guianensis (van Bénéden, 1864 foram recuperadas entre 20 de agosto de 2001 e 13 de fevereiro de 2006, na costa centro-norte fluminense. A maior parte delas (85% entre Barra de São João (22º35'S 41º59'W e Quissamã (22º06'S 41º28'W. Foram estudadas as colunas vertebrais dos 20 exemplares que apresentavam mais de 60% das vértebras presentes. A coleção é formada por 75% de animais imaturos, e todos os esqueletos mostram alterações tafonômicas mínimas. Duas categorias de anomalias congênitas foram diagnosticadas, ambas relacionadas ao desenvolvimento do mesoderma paraxial. A sétima vértebra cervical (C7 foi a única afetada, as costelas cervicais e o não fechamento do arco neural atingiram 15 (75% dos indivíduos analisados, dos quais três (15% apresentam ambas as anomalias. Nove (45% indivíduos apresentaram costelas cervicais uni ou bilateral, e nove (45% indivíduos apresentaram não fechamento do arco neural; em todos os casos as vértebras contíguas eram normais. A ocorrência de anomalias nesta série do Rio de Janeiro é maior do que as referidas na literatura brasileira para outras séries de Sotalia do Amazonas, Ceará e Santa Catarina. A série de Sotalia descrita vem de uma região do litoral muito limitada e provavelmente representa uma população local. As costelas cervicais são geneticamente determinadas e podem estar concentradas por uma condição de grande proximidade biológica entre os animais; o não fechamento do arco pode ter também um componente ambiental, a ser investigado futuramente.Carcasses of Guiana dolphins, Sotalia guianensis (van Bénéden, 1864 were recovered from August 20, 2001 to February 13, 2006 along the north-central coast of Rio de Janeiro state. Most of the animals (85% were found between Barra de São João (22º35'S 41º59'W and Quissamã (22º06'S 41º28'W. We studied the vertebral columns of all the 20 specimens that had more than 60% of the

  12. Essays in the Economics of Energy Development and Disamenities

    Science.gov (United States)

    Rakitan, Timothy J.

    This dissertation consists of three essays broadly themed around evaluating the impact of energy infrastructure on local consumers and industries. Taken together, they characterize ways in which the presence of energy activity is reflected in local land and labor market conditions, with a particular focus on the deployment of wind energy generation and shale resource extraction. The first chapter examines the relationship between the placement of wind energy infrastructure and house values and incomes in Iowa. The results suggest that income growth offsets some of the negative house-value effects commonly observed in the evaluation literature, but also that income gains reported in the literature are geographically distributed away from wind farm locations. I conclude that proximity to wind turbines does not increase the real incomes of local residents. The second chapter applies a regional model to county-level wage, house value, employment and energy production data to characterize the economic impact of the U.S. shale boom of the mid-2000s. While the boom has been responsible for wage and employment gains in counties located within the bounds of U.S. shale oil and gas plays, the net effect on house values has been negative. Within the set of energy-producing counties, however, house value declines are mitigated during the boom period as willingness-to-pay for residential space can overcome some of the negative impacts of energy industry activity. I conclude that shale energy extraction is a disamenity at the local level. The third chapter extends the analysis of the impact of the shale boom by examining possible spillovers in agriculture. Using parcel-level data from North Dakota, I analyze rental rates to assess the extent to which oil industry activity affects the returns to agricultural land. While "on-shale" parcels lease at lower rates than parcels located outside the oil fields, I cannot reject the hypothesis that proximity to an oil well has no impact on

  13. Essays on forecasting stationary and nonstationary economic time series

    Science.gov (United States)

    Bachmeier, Lance Joseph

    This dissertation consists of three essays. Chapter II considers the question of whether M2 growth can be used to forecast inflation at horizons of up to ten years. A vector error correction (VEC) model serves as our benchmark model. We find that M2 growth does have marginal predictive content for inflation at horizons of more than two years, but only when allowing for cointegration and when the cointegrating rank and vector are specified a priori. When estimating the cointegration vector or failing to impose cointegration, there is no longer evidence of causality running from M2 growth to inflation at any forecast horizon. Finally, we present evidence that M2 needs to be redefined, as forecasts of the VEC model using data on M2 observed after 1993 are worse than the forecasts of an autoregressive model of inflation. Chapter III reconsiders the evidence for a "rockets and feathers" effect in gasoline markets. We estimate an error correction model of gasoline prices using daily data for the period 1985--1998 and fail to find any evidence of asymmetry. We show that previous work suffered from two problems. First, nonstationarity in some of the regressors was ignored, leading to invalid inference. Second, the weekly data used in previous work leads to a temporal aggregation problem, and thus biased estimates of impulse response functions. Chapter IV tests for a forecasting relationship between the volume of litigation and macroeconomic variables. We analyze annual data for the period 1960--2000 on the number of cases filed, real GDP, real consumption expenditures, inflation, unemployment, and interest rates. Bivariate Granger causality tests show that several of the macroeconomic variables can be used to forecast the volume of litigation, but show no evidence that the volume of litigation can be used to forecast any of the macroeconomic variables. The analysis is then extended to bivariate and multivariate regression models, and we find similar evidence to that of the

  14. Essays on pricing dynamics, price dispersion, and nested logit modelling

    Science.gov (United States)

    Verlinda, Jeremy Alan

    The body of this dissertation comprises three standalone essays, presented in three respective chapters. Chapter One explores the possibility that local market power contributes to the asymmetric relationship observed between wholesale costs and retail prices in gasoline markets. I exploit an original data set of weekly gas station prices in Southern California from September 2002 to May 2003, and take advantage of highly detailed station and local market-level characteristics to determine the extent to which spatial differentiation influences price-response asymmetry. I find that brand identity, proximity to rival stations, bundling and advertising, operation type, and local market features and demographics each influence a station's predicted asymmetric relationship between prices and wholesale costs. Chapter Two extends the existing literature on the effect of market structure on price dispersion in airline fares by modeling the effect at the disaggregate ticket level. Whereas past studies rely on aggregate measures of price dispersion such as the Gini coefficient or the standard deviation of fares, this paper estimates the entire empirical distribution of airline fares and documents how the shape of the distribution is determined by market structure. Specifically, I find that monopoly markets favor a wider distribution of fares with more mass in the tails while duopoly and competitive markets exhibit a tighter fare distribution. These findings indicate that the dispersion of airline fares may result from the efforts of airlines to practice second-degree price discrimination. Chapter Three adopts a Bayesian approach to the problem of tree structure specification in nested logit modelling, which requires a heavy computational burden in calculating marginal likelihoods. I compare two different techniques for estimating marginal likelihoods: (1) the Laplace approximation, and (2) reversible jump MCMC. I apply the techniques to both a simulated and a travel mode

  15. Essays on globalization. Policies in trade, development, resources and climate change

    Energy Technology Data Exchange (ETDEWEB)

    Kerkelae, L.

    2009-07-01

    This research study on globalization consists of an introduction on the methodology applied, a summary and four independent essays focussing on applied policy research in international trade. The study follows the CGE (Computable General Equilibrium) research tradition. The simulation environment is the publicly available GTAP model. The essays examine the specific topics of trade and aid policies, price liberalization of the Russian energy markets, trade preferences in the sugar sector of the EU and the role of carbon sinks in mitigating climate change. The first essay examines trade and aid policies in Mozambique. The essay analyses the impact of alternative options like trade agreements, aid and trade facilitation. The results suggest that Mozambique has very little to gain from trade agreements or the Doha Round, although some agreements with the EU do yield some benefit. Trade facilitation and aid-for-trade programs on the other hand have the potential for larger benefits. The second essay examines the impact of liberalising RussiaAEs energy sector. The analysis is based on the implicit subsidies in regulated prices of electricity and gas and focuses on the effect of the different taxes and subsidies with respect to welfare and GDP in Russia and abroad. Increases in the price of electricity and gas improve efficiency and shift output from domestic markets to exports. The third essay investigates the impact of liberalising the EUAEs sugar sector by taking into account the complex structure of the EU sugar market and preferences in imports for developing countries. The fourth essay focuses on the effects of including carbon sinks into the analysis of the impacts of the Kyoto agreement. (orig.)

  16. Astr 101 Students' Attitudes Towards Essays On Transits, Eclipses And Occultations

    Science.gov (United States)

    D'Cruz, Noella L.

    2012-05-01

    Joliet Junior College, Joliet, IL offers a one semester introductory astronomy course each semester. We teach over 110 primarily non-science major students each semester. We use proven active learning strategies such lecture tutorials, think-pair-share questions and small group discussions to help these students develop and retain a good understanding of astrophysical concepts. Occasionally, we offer projects that allow students to explore course topics beyond the classroom. We hope that such projects will increase students' interest in astronomy. We also hope that these assignments will help students to improve their critical thinking and writing skills. In Spring 12, we are offering three short individual essay assignments in our face-to-face sections. The essays focus on transits, eclipses and occultations to highlight the 2012 transit of Venus. For the first essay, students will find images of transit and occultation events using the Astronomy Picture of the Day website and describe their chosen events. In addition, students will predict how variations in certain physical and orbital parameters would alter their particular events. The second essay involves transits, eclipses and occultations observed by spacecraft. Students will describe their transit event, their spacecraft's mission, orbital path, how the orbital path was achieved, etc. The third essay deals with transiting exoplanets. Students will choose at least two exoplanets from an exoplanet database, one of which has been discovered through the transit method. This essay will enable students to learn about detecting exoplanets and how they compare with our solar system. Details of the essay assignments and students' reactions to them will be presented at the meeting.

  17. Metadiscourse in persuasive essays by elementary students in South Korea and the US

    Directory of Open Access Journals (Sweden)

    Kim Il-Hee

    2017-05-01

    Full Text Available This study investigated metadiscourse in the persuasive essays of fourth graders from both urban and rural communities: 224 students in South Korea and 188 in the US. Each student was asked to write a persuasive essay in his or her native Korean or English in response to a story not previously read or discussed. Analysis with a taxonomy developed by Hyland (2004 indicated significant differences in the metadiscourse by country. In terms of interactive metadiscourse, South Korean students used more sentence-level transitions than U.S. students, who used more frame markers and endophoric markers. With regard to interactional metadiscourse, U.S. students used more hedges, boosters, engagement markers, and self-mentions in their essays. This study also compared the students′ essays by the type of community in which the writers lived. In the US the essays of students in rural communities contained more hedges, whereas those of students in urban areas included significantly more self-mentions. In South Korea, no significant difference was detected in the metadiscourse of students living in rural and urban areas.

  18. HGSA DNA day essay contest winner 60 years on: still coding for cutting-edge science.

    Science.gov (United States)

    Yates, Patrick

    2013-08-01

    MESSAGE FROM THE EDUCATION COMMITTEE: In 2013, the Education Committee of the Human Genetics Society of Australasia (HGSA) established the DNA Day Essay Contest in Australia and New Zealand. The contest was first established by the American Society of Human Genetics in 2005 and the HGSA DNA Day Essay Contest is adapted from this contest via a collaborative partnership. The aim of the contest is to engage high school students with important concepts in genetics through literature research and reflection. As 2013 marks the 60th anniversary of the discovery of the double helix of DNA by James Watson and Francis Crick and the 10th anniversary of the first sequencing of the human genome, the essay topic was to choose either of these breakthroughs and explain its broader impact on biotechnology, human health and disease, or our understanding of basic genetics, such as genetic variation or gene expression. The contest attracted 87 entrants in 2013, with the winning essay authored by Patrick Yates, a Year 12 student from Melbourne High School. Further details about the contest including the names and schools of the other finalists can be found at http://www.hgsa-essay.net.au/. The Education Committee would like to thank all the 2013 applicants and encourage students to enter in 2014.

  19. Essays on Industry Response to Energy and Environmental Policy

    Science.gov (United States)

    Sweeney, Richard Leonard

    This dissertation consists of three essays on the relationship between firm incentives and energy and environmental policy outcomes. Chapters 1 and 2 study the impact of the 1990 Clean Air Act Amendments on the United States oil refining industry. This legislation imposed extensive restrictions on refined petroleum product markets, requiring select end users to purchase new cleaner versions of gasoline and diesel. In Chapter 2, I estimate the static impact of this intervention on refining costs, product prices and consumer welfare. Isolating these effects is complicated by several challenges likely to appear in other regulatory settings, including overlap between regulated and non-regulated markets and deviations from perfect competition. Using a rich database of refinery operations, I estimate a structural model that incorporates each of these dimensions, and then use this cost structure to simulate policy counterfactuals. I find that the policies increased gasoline production costs by 7 cents per gallon and diesel costs by 3 cents per gallon on average, although these costs varied considerably across refineries. As a result of these restrictions, consumers in regulated markets experienced welfare losses on the order of 3.7 billion per year, but this welfare loss was partially offset by gains of 1.5 billion dollars per year among consumers in markets not subject to regulation. The results highlight the importance of accounting for imperfect competition and market spillovers when assessing the cost of environmental regulation. Chapter 2 estimates the sunk costs incurred by United States oil refineries as a result of the low sulfur diesel program. The complex, regionally integrated nature of the industry poses many challenges for estimating these costs. I overcome them by placing the decision to invest in sulfur removal technology within the framework of a two period model and estimate the model using moment inequalities. I find that the regulation induced between 2

  20. Tales from the front lines: the creative essay as a tool for teaching genetics.

    Science.gov (United States)

    Koehler, K E; Hawley, R S

    1999-07-01

    In contrast to the more typical mock grant proposals or literature reviews, we describe the use of the creative essay as a novel tool for teaching human genetics at the college level. This method has worked well for both nonmajor and advanced courses for biology majors. The 10- to 15-page essay is written in storylike form and represents a student's response to the choice of 6-8 scenarios describing human beings coping with various genetic dilemmas. We have found this tool to be invaluable both in developing students' ability to express genetic concepts in lay terms and in promoting student awareness of genetic issues outside of the classroom. Examples from student essays are presented to illustrate these points, and guidelines are suggested regarding instructor expectations of student creativity and scientific accuracy. Methods of grading this assignment are also discussed.

  1. Humanizing mathematics and its philosophy essays celebrating the 90th birthday of Reuben Hersh

    CERN Document Server

    2017-01-01

    This Festschrift contains numerous colorful and eclectic essays from well-known mathematicians, philosophers, logicians, and linguists celebrating the 90th birthday of Reuben Hersh. The essays offer, in part, attempts to answer the following questions set forth by Reuben himself as a focus for this volume: Can practicing mathematicians, as such, contribute anything to the philosophy of math? Can or should philosophers of math, as such, say anything to practicing mathematicians? Twenty or fifty years from now, what will be similar, and what will, or could, or should be altogether different: About the philosophy of math? About math education? About math research institutions? About data processing and scientific computing? The essays also offer glimpses into Reuben’s fertile mind and his lasting influence on the mathematical community, as well as revealing the diverse roots, obstacles and philosophical dispositions that characterize the working lives of mathematicians. With contributions from a veritable “w...

  2. Scoring and setting pass/fail standards for an essay certification examination in nurse-midwifery.

    Science.gov (United States)

    Fullerton, J T; Greener, D L; Gross, L J

    1992-03-01

    Examination for certification or licensure of health professionals (credentialing) in the United States is almost exclusively of the multiple choice format. The certification examination for entry into the practice of the profession of nurse-midwifery has, however, used a modified essay format throughout its twenty-year history. The examination has recently undergone a revision in the method for score interpretation and for pass/fail decision-making. The revised method, described in this paper, has important implications for all health professional credentialing agencies which use modified essay, oral or practical methods of competency assessment. This paper describes criterion-referenced scoring, the process of constructing the essay items, the methods for assuring validity and reliability for the examination, and the manner of standard setting. In addition, two alternative methods for increasing the validity of the pass/fail decision are evaluated, and the rationale for decision-making about marginal candidates is described.

  3. Four essays on the economics of climate change - with a supplement

    International Nuclear Information System (INIS)

    Torvanger, A.

    1993-01-01

    Climate change has been a main environmental issue over the last decade. The atmospheric concentration of some trace gases are increased through various human activities. Some of these trace gases, the greenhouse gases (GHGs), are transparent to incoming solar radiation, but absorb the infrared radiation from the Earth's surface. Through this mechanism the GHGs are able to induce global warming and climate change, even if their concentration is relatively low. The essays of this dissertation relate to different aspects of the climate change issue. The first essay and the supplement analyze the carbon dioxide emission sources and the distribution of emissions. In the first essay, ''Manufacturing sector carbon dioxide emissions in nine OECD countries 1973-87'', the relation between carbon dioxide emissions in manufacturing and output, structure, energy source mix and technology is discussed. In the supplement, ''Global, regional and national carbon dioxide emissions 1949-86'', the geographical distribution and time series of emissions are described. The next three essays relate to various aspects of climate policy. In ''An optimal growth model for Norway with a carbon dioxide emissions constraint'', the focus is on the economic consequences of an emissions abatement policy implemented as a carbon tax on fossil fuels. The topic of the subsequent essay, ''Efficient contracts in a game of nations pursuing greenhouse gas emissions abatement'', is the design and enforcement by a policing institution of efficient contracts to reduce GHG emissions under country moral hazard. Finally, in the last essay, ''Uncertain change in an intergenerational planning model'', some long-term aspects of climate policy such as intergenerational equity and uncertainty are analyzed

  4. Electrochemical noise measurements techniques and the reversing dc potential drop method applied to stress corrosion essays

    International Nuclear Information System (INIS)

    Aly, Omar Fernandes; Andrade, Arnaldo Paes de; MattarNeto, Miguel; Aoki, Idalina Vieira

    2002-01-01

    This paper aims to collect information and to discuss the electrochemical noise measurements and the reversing dc potential drop method, applied to stress corrosion essays that can be used to evaluate the nucleation and the increase of stress corrosion cracking in Alloy 600 and/or Alloy 182 specimens from Angra I Nuclear Power Plant. Therefore we will pretend to establish a standard procedure to essays to be realized on the new autoclave equipment on the Laboratorio de Eletroquimica e Corrosao do Departamento de Engenharia Quimica da Escola Politecnica da Universidade de Sao Paulo - Electrochemical and Corrosion Laboratory of the Chemical Engineering Department of Polytechnical School of Sao Paulo University, Brazil. (author)

  5. Games in libraries essays on using play to connect and instruct

    CERN Document Server

    Kirsch, Breanne A

    2014-01-01

    Librarians are beginning to see the importance of game based learning and the incorporation of games into library services. This book is written for them--so they can use games to improve people's understanding and enjoyment of the library. Full of practical suggestions, the essays discuss not only innovative uses of games in libraries but also the game making process. The contributors are all well versed in games and game-based learning and a variety of different types of libraries are considered. The essays will inspire librarians and educators to get into this exciting new area of patron

  6. The Multimedia Essay. The Information Technologies as a Tool for The Humanities’ Statements

    Directory of Open Access Journals (Sweden)

    Piotr Cichocki

    2012-06-01

    Full Text Available The article applies for the educational experiment practiced during last several years at The Institute of Ethnology and Culture Anthropology, University of Warsaw, related to the multimedia essay. More accomplished than a multimedia presentation, more connected with textual analysis than a movie or videoclip, the multimedia essay may be mean especially fitted to humanities’ statements. The kind of attempts may result in the new discoursive hypertextual field, however nowadays they deal with dilemmas connected with copyrights and corporative control under the datas. Therefore the science is entangled with processes of constant change in the legislation.

  7. Three essays on the incentive structure of energy conservation programs

    Science.gov (United States)

    Okwelum, Edson Ogochukwu

    This dissertation is comprised of three related essays examining the potential effectiveness of government energy efficiency programs from both the producer and consumer perspectives. The first chapter is based on a paper I coauthored with Corey Lang. In this manuscript, I address the question of whether strategic behavior by consumers could result in the erosion of energy savings in a demand response program. Understanding how the strategic behavior of consumers affects the net benefits from a demand response program has policy implications because of the increasing importance that demand response has come to play in utility load and reliability management during peak times. Using data from a large field experiment in California in 2007, we test the hypothesis that under a technology program, consumers' strategic behavior results in outcomes that are opposite what is obtainable under a program with price incentive or based of behavior. Chapter II is also an empirical study which explores how the preferences of consumers for large and heavy vehicles imposes costs on society in the form of external costs of accident. This chapter looks at how fleet changes in weight distribution due to corporate average fuel economy and consumer demand for heavier vehicles results in fatalities. It is important to understand how consumer behavior affects the accident rates so that one can obtain unbiased estimates of accident costs that go into benefit-cost analysis of the impact of regulations in automobiles. Chapter three addresses how unobserved heterogeneity and sorting affect the estimates of the consumer willingness to pay for reduction in future gasoline costs. This tradeoff is important to policy makers and manufactures because it could help explain why manufacturers fail to adopt technologies for which the fuel savings far outweigh the costs. The remainder of the abstract provides a more detailed outlines of the three essays. Chapter 1 explores strategic behavior by

  8. Essays on the economics of natural gas pipelines

    Science.gov (United States)

    Oliver, Matthew E.

    The natural gas pipeline transportation industry is comprised of a primary market and a secondary market. In the primary market, pipelines sell 'firm' transport capacity contracts to gas traders, local distribution companies, and other parties. The (per unit) secondary market value of transport is rarely comparable to the regulated primary market two-part tariff. When and where available capacity in the secondary market is scarce, its value can far exceed the primary market tariffs paid by firm contract holders, generating scarcity rents. The following essays demonstrate that this phenomenon has predictable effects on natural gas spot prices, firm capacity reservations, the pipeline's capacity construction and expansion decisions, and the economic welfare of producers and consumers at the market hubs connected by the pipeline. Chapter 1 provides a theoretical framework for understanding how pipeline congestion affects natural gas spot prices within the context of the current regulatory environment, and empirically quantifies this effect over a specific regional pipeline network. As available pipeline capacity over a given route connecting two hubs becomes scarce, the spot prices for gas at the hubs are driven apart---a phenomenon indicative of some market friction that inhibits the ability of spot price arbitrage to fully integrate the two prices, undermining economic efficiency. The theoretical component of Chapter 1 illuminates a potential source of this friction: the deregulated structure of the secondary market for gas transportation services. To support and quantify the predictions of the theoretical model, the empirical component demonstrates that the effect of congestion on the secondary market value of transport---the key factor in driving apart spot prices---can be quite strong. Coefficient estimates indicate that dramatic increases in transport costs are likely to result from marginal increases in congestion. This result has important implications because

  9. To Write or to Type? The Effects of Handwriting and Word-Processing on the Written Style of Examination Essays

    Science.gov (United States)

    Mogey, Nora; Hartley, James

    2013-01-01

    There is much debate about whether or not these days students should be able to word-process essay-type examinations as opposed to handwriting them, particularly when they are asked to word-process everything else. This study used word-processing software to examine the stylistic features of 13 examination essays written by hand and 24 by…

  10. Reflecting on 25 Years of Teaching, Researching, and Textbook Writing for Introduction to Management: An Essay with Some Lessons Learned

    Science.gov (United States)

    Dyck, Bruno

    2017-01-01

    This essay describes innovations made and lessons learned while teaching introduction to management courses during a 25-year career. The essay describes how teaching two approaches to management increases students' critical and ethical thinking, and reverses the tendency for business students to become increasingly materialistic and…

  11. An Examination of the Instruction Provided in Australian Essay Guides for Students' Development of a Critical Viewpoint

    Science.gov (United States)

    Hammer, Sara

    2017-01-01

    The argumentative essay has endured as a popular form of university assessment, yet students still struggle to meet key intended learning outcomes, such as those associated with critical thinking. This paper presents the results of a study that examines the instruction provided by Australian essay writing guides to support students' development of…

  12. The Role of Women in Foreign-Language Textbooks: A Collection of Essays. Collection d'"Etudes linguistiques" No. 24.

    Science.gov (United States)

    Freudenstein, R., Ed.

    Essays that consider the way that women are portrayed in foreign language textbooks are presented. The selected essays were submitted to a competition sponsored by the Federation Internationale des Professeurs de Langues Vivantes, which requested that language teachers assess such concerns as: (1) whether women were described in a stereotyped way;…

  13. Effectiveness of a Test-Taking Strategy on Achievement in Essay Tests for Students with Learning Disabilities

    Science.gov (United States)

    Therrien, William J.; Hughes, Charles; Kapelski, Cory; Mokhtari, Kouider

    2009-01-01

    Research was conducted to ascertain if an essay-writing strategy was effective at improving the achievement on essay tests for 7th- and 8th-grade students with reading and writing disabilities. Students were assigned via a stratified random sample to treatment or control group. Student scores were also compared to students without learning…

  14. 'Korenizatsiia' and its Discontents: Ukraine and the Soviet Nationality Policies during the 1920s: A Review Essay

    OpenAIRE

    VUSHKO, Iryna

    2009-01-01

    This essay reviews the recent literature on the nationalities policy in Soviet Ukraine during the 1920s. It brings together different Western (English and German) and native (Ukrainian and Russian) historical narratives, all produced after 2001. Different approaches to the Soviet nationalities policy, as this essay demonstrates, reveal broader methodological differences between historians working within distinct historiographical traditions. Despite the increasing contacts between...

  15. Automated Subscores for TOEFL iBT[R] Independent Essays. Research Report. ETS RR-11-39

    Science.gov (United States)

    Attali, Yigal

    2011-01-01

    The e-rater[R] automated essay scoring system is used operationally in the scoring of TOEFL iBT[R] independent essays. Previous research has found support for a 3-factor structure of the e-rater features. This 3-factor structure has an attractive hierarchical linguistic interpretation with a word choice factor, a grammatical convention within a…

  16. Cohesion and the Social Construction of Meaning in the Essays of Filipino College Students Writing in L2 English

    Science.gov (United States)

    Castro, Carolyn D.

    2004-01-01

    This study compares the degree of cohesion and coherence in the essays written by thirty Filipino college freshmen and analyzes how the social construction of meaning was made evident in their writing. Results showed that low, mid and highly rated essays were comparable in grammatical cohesive device use. Lexical repetition and use of synonyms…

  17. Suffering eases over time: the experience of families in the care of children with congenital anomalies El sufrimiento amenizado con el tiempo: la experiencia de la familia en el cuidado del niño con anomalía congénita O sofrimento amenizado com o tempo: a experiência da família no cuidado da criança com anomalia congênita

    Directory of Open Access Journals (Sweden)

    Cristiana Araújo Guiller

    2009-08-01

    Full Text Available This study aimed to understand the experience of caring for a child with a congenital anomaly from the family's perspective. Symbolic Interactionism and Grounded Theory were the theoretical and methodological references, respectively. Data collection was carried out with eight families with children having congenital anomalies through semi-structured interviews and participating observation. Data analysis reached axial coding. Results revealed two phenomena in the experience of families in delivering care to children with congenital anomalies - Facing an initially difficult experience and suffering eases over time. We concluded that the understanding of this experience supports the need to reconsider the nursing care provided to families in the care of children with congenital anomalies.El objetivo de este estudio fue comprender el significado de la vivencia del proceso de cuidar de niños con anomalía congénita bajo la perspectiva de la familia. El Interaccionismo Simbólico y la Teoría Fundamentada en los Datos fueron utilizados como marcos teóricos y metodológicos, respectivamente. La recolección de los datos fue realizada en ocho familias de niños con anomalía congénita, utilizándose la entrevista semiestructurada y la observación participante. El análisis de los datos fue conducido hasta la codificación axial. Como resultados, fueron evidenciados dos fenómenos en la vivencia de la familia al cuidar del niño con anomalía congénita: deparándose con una vivencia inicialmente difícil, y teniendo el sufrimiento amenizado con el tiempo. Se concluye que la comprensión de esa vivencia ofrece subsidios importantes para repensar la asistencia de enfermería a la familia que cuida de niños con anomalía congénita.O objetivo deste estudo foi compreender o significado da vivência do processo de cuidar da criança com anomalia congênita sob a perspectiva da família. O Interacionismo Simbólico e a Teoria Fundamentada nos Dados

  18. Coherence in the Argumentative Essays of First Year College of Liberal Arts Students at De La Salle University

    Directory of Open Access Journals (Sweden)

    Alphie G. Garing

    2013-12-01

    Full Text Available The study investigates five textual features of coherence in the students’ argumentative essays for text comprehensibility and overall writing quality. Specifically, it examines how comprehensible the students’ argumentative essays considering the following: focus, organization, cohesion, support and elaboration, and conventions; and the relationship between the textual features and the comprehensibility of the students’ argumentative essays. The data consists of 13 argumentative essays written in ENGLCOM class first year College of Liberal Arts students of De La Salle University. Two techniques were used to analyze the data. First, an analytic and holistic scorings using a four-point writing rubric were used to evaluate each of the textual features of coherence and comprehensibility, respectively. Second, correlation analysis was performed to determine the relationship between the coherence features and the comprehensibility of the students’ texts and between the comprehensibility of the students’ argumentative essays.

  19. Material Teaching Aids: Enhancement Tool for Teaching Essay Writing in Secondary Schools

    Science.gov (United States)

    Fidelia, Okonkwo Adaobi

    2015-01-01

    The purpose of this study is to investigate the use of material teaching aids as enhancement tool for teaching essay writing in secondary schools in Ebonyi State. A 4-point Likert-scale questionnaire was used as the instrument. A trial test was conducted and tested for reliability and a value of 0.75 was obtained from the test. The instrument was…

  20. Accounting Issues: An Essay Series Part VI--Investments in Securities

    Science.gov (United States)

    Laux, Judy

    2008-01-01

    The sixth in a series of theory-based essays, this article presents accounting for investments in debt and equity securities along with some related conceptual and measurement issues. Additional coverage is devoted to potential ethical dilemmas and both theoretical and empirical literature related to this asset. (Contains 1 footnote.)

  1. Prognosis Essay Scoring and Article Relevancy Using Multi-Text Features and Machine Learning

    Directory of Open Access Journals (Sweden)

    Arif Mehmood

    2017-01-01

    Full Text Available This study develops a model for essay scoring and article relevancy. Essay scoring is a costly process when we consider the time spent by an evaluator. It may lead to inequalities of the effort by various evaluators to apply the same evaluation criteria. Bibliometric research uses the evaluation criteria to find relevancy of articles instead. Researchers mostly face relevancy issues while searching articles. Therefore, they classify the articles manually. However, manual classification is burdensome due to time needed for evaluation. The proposed model performs automatic essay evaluation using multi-text features and ensemble machine learning. The proposed method is implemented in two data sets: a Kaggle short answer data set for essay scoring that includes four ranges of disciplines (Science, Biology, English, and English language Arts, and a bibliometric data set having IoT (Internet of Things and non-IoT classes. The efficacy of the model is measured against the Tandalla and AutoP approach using Cohen’s kappa. The model achieves kappa values of 0.80 and 0.83 for the first and second data sets, respectively. Kappa values show that the proposed model has better performance than those of earlier approaches.

  2. Effects of Analytical and Holistic Scoring Patterns on Scorer Reliability in Biology Essay Tests

    Science.gov (United States)

    Ebuoh, Casmir N.

    2018-01-01

    Literature revealed that the patterns/methods of scoring essay tests had been criticized for not being reliable and this unreliability is more likely to be more in internal examinations than in the external examinations. The purpose of this study is to find out the effects of analytical and holistic scoring patterns on scorer reliability in…

  3. Deepening, Broadening and Scaling up: a Framework for Steering Transition Experiments. : Essay 02

    NARCIS (Netherlands)

    S.J.M. van den Bosch (Suzanne); J. Rotmans (Jan)

    2008-01-01

    markdownabstractThis essay presents a conceptual framework for analyzing and influencing the contribution of small-scale experiments to transitions towards a more sustainable society. This framework is aimed at providing academics and practitioners with a theoretical and practice oriented

  4. A Window to the Past: What an Essay Contest Reveals about Early American Education

    Science.gov (United States)

    Justice, Benjamin

    2015-01-01

    In 1795 America's premier scholarly association, the American Philosophical Society (APS), posed the following question: [Write] an essay on a system of liberal education, and literary instruction, adapted to the genius of the government, and best calculated to promote the general welfare of the United States; comprehending, also, a plan for…

  5. This Bridge Called My Leadership: An Essay on Black Women as Bridge Leaders in Education

    Science.gov (United States)

    Horsford, Sonya Douglass

    2012-01-01

    The purpose of this essay is to contextualize the existing research literature on leadership for diversity, equity, and social justice in education with "bridge leadership" as historically practiced by Black women leaders in the USA. Its primary aim is to demonstrate how the intersection of race and gender as experienced by the Black…

  6. The Donkey Institute of Contemporary Art (DICA): A Photo-Essay

    OpenAIRE

    Yam Lau

    2014-01-01

    This photo-essay documents the conception and realization of a ‘mobile display unit,’ a kind of cabinet of curiosities attached to a donkey, and made to travel through the streets of Beijing so that the texts, works and videos displayed there were accessible to passers-by.

  7. The Donkey Institute of Contemporary Art (DICA: A Photo-Essay

    Directory of Open Access Journals (Sweden)

    Yam Lau

    2014-02-01

    Full Text Available This photo-essay documents the conception and realization of a ‘mobile display unit,’ a kind of cabinet of curiosities attached to a donkey, and made to travel through the streets of Beijing so that the texts, works and videos displayed there were accessible to passers-by.

  8. Edgeware Security Risk Management: A Three Essay Thesis on Cloud, Virtualization and Wireless Grid Vulnerabilities

    Science.gov (United States)

    Brooks, Tyson T.

    2013-01-01

    This thesis identifies three essays which contribute to the foundational understanding of the vulnerabilities and risk towards potentially implementing wireless grid Edgeware technology in a virtualized cloud environment. Since communication networks and devices are subject to becoming the target of exploitation by hackers (e.g. individuals who…

  9. Jane Austen: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Watt, Ian, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Virginia Woolf, C. S. Lewis, Edmund Wilson, Ian Watt, Alan D. McKillop, Reuben A. Brower, Marvin Mudrick, Mark Schorer, Arnold Kettle, Lionel Trilling, Kingsley Amis, Andrew H. Wright, Donald J. Greene, and D. W.…

  10. Using the Creative Cognition Approach in Essay Assignments in Leadership Education

    Science.gov (United States)

    Atkinson, Tim

    2018-01-01

    This application brief covers, "The Final Question," an alternative essay design that encourages the learner to think creatively in Ph.D. Organization Theory or Leadership courses. "The Final Question" asks, "Do leaders change organizations or do organizations change leaders?" It is a simple question, but only the…

  11. Tutor Feedback on Draft Essays: Developing Students' Academic Writing and Subject Knowledge

    Science.gov (United States)

    Court, Krista

    2014-01-01

    Providing feedback on draft essays is an accepted means of enacting a social-constructivist approach to assessment, aligning with current views on the value of formative feedback and assessment for learning (AFL). However, the use of this process as a means of improving not only content but also students' academic writing skills has not been…

  12. STUDENTS’ PERCEPTIONS OF THEIR REFLECTIVE ESSAY WRITING EXPERIENCE AND TEACHER FEEDBACK COMMENTS

    Directory of Open Access Journals (Sweden)

    Asiah Mohd Sharif

    2017-01-01

    Full Text Available Reflection which encompasses critical and analytical capabilities is a critical 21st century skill for students to develop. To ensure students are equipped with this skill, reflective writing has been identified as a possible tool. Teacher feedback on students’ written output therefore plays a role in developing students’ reflective skills. This study asks two questions: How do students perceive their experience writing reflective essays? What is the nature of the teacher’s feedback comments on students’ reflective essays and how do students perceive them? To answer these questions, nineteen ESL students in an entry-level Medical programme completed a questionnaire concerning their experiences writing reflective essays and perceptions of teacher feedback on these essays. Interviews were conducted with two students to follow-up on questionnaire responses. The content analysis showed that the students believed reflective writing played a small contribution to their language learning. Further investigation into the students’ perspectives of their teachers’ feedback comments suggests that even though the teachers’ feedback was positive, the students also referred to the comments as inadequate and ineffective. Pedagogical implications and suggestions for future research are discussed.

  13. PICTORIAL ESSAY Bamboo spine – X-ray findings of ankylosing ...

    African Journals Online (AJOL)

    Pathology and imaging characteris- tics. In this pictorial essay, we focus on the characteristic axial skeleton imaging findings of AS, as it presents on conventional X-ray:1. • florid anterior spondylitis (Romanus lesions). • florid diskitis (Andersson lesions). Ankylosing spondylitis is a debilitating disease that is one of the sero-.

  14. Taking Stock, Placing Orders: A Historiographic Essay on the Business History of the Newspaper.

    Science.gov (United States)

    Smith, Carol; Dyer, Carolyn Stewart

    This historiographic essay discusses and seeks to begin to address the need for a business history of the newspaper. The paper's first section clarifies the terms "business history,""economic history,""political history," and "history of economics," (which the paper suggests have been used interchangeably in…

  15. Two Essays on Learning Disabilities in the Application of Fundamental Financial Principles

    Science.gov (United States)

    Auciello, Daria Joy

    2010-01-01

    This dissertation consists of two essays which examine the relationship between dyslexia and the application and acquisition of financial knowledge. Recent behavioral research has documented that factors such as representativeness, overconfidence, loss aversion, naivete, wealth, age and gender all impact a person's risk perception and asset…

  16. The Flight from Reason. Essays on Intellectual Freedom in the Academy, the Press, and the Library.

    Science.gov (United States)

    Berninghausen, David K.

    David K. Berninghousen's writings on intellectual freedom in the library, the university, and the press are collected in this volume. These essays cover the education of librarians for intellectual freedom, the communications process, the threat to liberal values (intellectualism, objectivity) in the communications institutions, the erosion of…

  17. Essays on the valuation of discretionary liabilities and pension fund investment policy

    NARCIS (Netherlands)

    Broeders, D.W.G.A.

    2010-01-01

    The four essays collected in this dissertation serve as a contribution to the broad field of pension finance. They focus on the economic understanding of liability valuation on the one hand and investment policy for pension funds on the other. The first article concerns the impact of the sponsor’s

  18. Accounting Issues: An Essay Series Part IX--Statement of Cash Flows

    Science.gov (United States)

    Laux, Judy

    2009-01-01

    This essay series, beginning with Laux [2007a], defends the proposition that eliminating the theoretical chapter from the principles level accounting course has weakened the introduction for students new to this subject, perhaps resulting in some adverse selection for the accounting profession. As a remedy, it offers concise theoretical articles…

  19. Solving the Students’ Problems in Writing Argumentative Essay Through the Provision of Planning

    Directory of Open Access Journals (Sweden)

    Lestari Setyowati

    2017-10-01

    Full Text Available Most Indonesian students who are learning English often consider writing as not only the most difficult skill to master, but also a demanding activity. To help them cope these problems, the application of planning in the writing process seems to be a solution. This study attempts to find out howdifferent planning formats can improve EFL students’ writing performance in argumentative essays. The subjects of the studywere the fourth semester students taking essay writing class. The research was conducted from May to June 2015, consisting of three cycles in Classroom Action Research design by using different planning types, namely rough drafting and outlining strategy in which each cycle consisted of two meetings.The students’ compositions were measured by using primary trait scoring rubric for argumentative essay. The result of the study shows that the provision of planning is effective to improve the students’ performance in writing argumentative essay. The effectiveness of different types planningdepends on the students’ preference of which to use.

  20. Correlation Between Lexical Richness and Overall Quality of Argumentative Essays Written by English Department Students

    Directory of Open Access Journals (Sweden)

    Rizky Lutviana

    2015-03-01

    Full Text Available Abstract: This study aims at revealing the contribution of diction to the overall quality of argumenta-tive essays written by 42 EFL students. The researcher compared two sets of scores, the score of students’ lexical richness, measured with LFP (Lexical Frequency Profile, and the score of overall quality of EFL students’ argumentative essay, using analytical scoring rubric. The small and not significant correlation (ñ=.18, sig=.23 implied that diction had small contribution to the overall quality of the essay. There might be another factor related to the diction that supports the quality of written text. Thus, further research is needed to be conducted. Key Words: diction, lexical richness, overall quality, argumentative essay Abstrak: Penelitian ini bertujuan untuk menemukan kontribusi diksi untuk kualitas keseluruhan dari esai argumentatif yang ditulis oleh 42 siswa EFL. Peneliti membandingkan dua set nilai, skor siswa kekayaan leksikal, diukur dengan LFP (Lexical Frequency Profile, dan skor keseluruhan kualitas siswa EFL pada esai argumentatif, dengan menggunakan rubrik skoring analitis. Korelasi kecil dan tidak signifikan (ñ = 0,18, sig = 0,23 menunjukkan bahwa diksi memiliki kontribusi kecil untuk kualitas keseluruhan dari esai. Kemungkinan, ada faktor lain yang berhubungan dengan diksi yang mendukung kualitas dari teks. Dengan demikian, penelitian lebih lanjut diperlukan untuk dilakukan. Kata kunci: diksi, kekayaan leksikal, kualitas secara keseluruhan, esai argumentatif