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Sample records for erythroxylum coca control

  1. Biological activity of the alkaloids of Erythroxylum coca and Erythroxylum novogranatense

    NARCIS (Netherlands)

    Salemink, C.A.; Novák, M.; Khan, I.

    1984-01-01

    The cultivated Erythroxylum varieties E. coca var. coca, E. coca var. ipadu, E. novogranatense var. novogranatense and E. novogranatense var. truxillense contain 18 alkaloids, identified so far, belonging to the tropanes, pyrrolidines and pyridines, with cocaine as the main alkaloid. The biological

  2. Colombian coca plants. A critical discussion on taxonomic aspects of cultivated Erythroxylum species (Erythroxylaceae)

    International Nuclear Information System (INIS)

    Galindo Bonilla, Aida; Fernandez Alonzo, Jose Luis

    2010-01-01

    Forensic botany is in high demand in Colombia in connection with plant material, mainly coca from illicit crops. The taxonomic study of the two species and four varieties of Erythroxylum P. Browne (Erythroxylaceae) cultivated in Colombia was carried out. Hybridization between E. coca and E. novogranatense and between the two varieties of E. coca is suggested, and important changes in the geographic distribution of all taxa are described. Both, hybridization and changes in distribution patterns are due to anthropic intervention.

  3. Especies vegetales empleadas en la insalivación de hojas de “coca” (Erythroxylum coca var. Coca, Erythroxylaceae

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    Norma I. Hilgert

    2000-01-01

    Full Text Available Hilgert, N. I. 2000. Especies vegetales empleadas en la insalivación de hojas de “coca”(Erythroxylum coca var. coca, Erythroxylaceae. Darwiniana 38(3-4: 241-252.El estudio se desarrolló en comunidades campesinas de la selva nublada, en la alta cuenca del ríoBermejo, Provincia de Salta, Argentina con el objeto de documentar el uso de plantas involucradas en laelaboración de “yista”. “Yista” es el nombre asignado a las sustancias alcalinas utilizadas durante lainsalivación de hojas de coca (Erythroxylum coca Lam. var. coca. Para la obtención de la “yista” lasplantas seleccionadas deben ser incineradas. Se registraron veintisiete especies nativas y cinco exóticasempleadas, en el presente o en el pasado, para preparar “yista”. Se mencionan los nombres científicos yvulgares y las porciones de la planta utilizadas, y la comunidad donde se registró el uso. Se describe eilustra el modo de preparar “yista”

  4. Effect of the aqueous, acidic and alcoholic extract of dried leaves of Erythroxylum coca var. coca (coca in Trichophyton rubrum, Trichophyton mentagrophytes, Microsporum canis and Candida albicans in vitro

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    Medalit Luna-Vílchez

    2017-06-01

    Full Text Available Objective: To evaluate the effect of the aqueous, acidic and alcoholic extract of dried leaves of Erythroxylum coca var. coca (coca in Trichophyton rubrum (TR, Trichophyton mentagrophytes (TM, Microsporum canis (MC and Candida albicans (CA in vitro. Materials and methods: An experimental study which evaluated the presence or absence of fungal growth, and fungal growth rate from the seeding point, compared to fungal growth in Sabouraud Agar (SA using Siegel-Tukey and KruskalWallis tests (p<0.05. Results: The CA group showed a statistical difference (p<0.05 between the following groups: 99.9% ethanol vs. aqueous, 99.9% ethanol vs. 0.01M HCl, 99.9% ethanol vs. control, control vs. aqueous, 0.01M HCl vs. control. The TR group showed a statistical difference (p<0.05 between the following groups: 99.9% ethanol vs. 0.01M HCl, 99.9% ethanol vs. aqueous, 99.9% ethanol vs. control, 0.01M HCl vs. control. The TM group showed a statistical difference (p<0.05 between the following groups: 99.9% ethanol vs. 0.01M HCl, 99.9% ethanol vs. control, aqueous vs. acid, aqueous vs. control. The MC group showed a statistical difference (p<0.05 between the following groups: 99.9% ethanol vs. 0.01M HCl, 99.9% ethanol vs. control, aqueous vs. acid, aqueous vs. control. In all the cases, the results of the 0.01M HCl vs. aqueous group were not significant. Conclusions: The aqueous, acidic and alcoholic extracts have no effect on the growth of CA and TM, but the alcoholic extract has effects on the growth of TR and MC. In addition, there were differences in the growth rate of CA, TR and TM in the aqueous, acidic and alcoholic extracts compared to that in SA. However only TR, TM and MC showed differences in their growth rate in the alcoholic extract.

  5. Selection and validation of reference genes for quantitative gene expression studies in Erythroxylum coca [v1; ref status: indexed, http://f1000r.es/y1

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    Teresa Docimo

    2013-02-01

    Full Text Available Real-time quantitative PCR is a powerful technique for the investigation of comparative gene expression, but its accuracy and reliability depend on the reference genes used as internal standards. Only genes that show a high level of expression stability are suitable for use as reference genes, and these must be identified on a case-by-case basis. Erythroxylum coca produces and accumulates high amounts of the pharmacologically active tropane alkaloid cocaine (especially in the leaves, and is an emerging model for the investigation of tropane alkaloid biosynthesis. The identification of stable internal reference genes for this species is important for its development as a model species, and would enable comparative analysis of candidate biosynthetic genes in the different tissues of the coca plant. In this study, we evaluated the expression stability of nine candidate reference genes in E. coca (Ec6409, Ec10131, Ec11142, Actin, APT2, EF1α, TPB1, Pex4, Pp2aa3. The expression of these genes was measured in seven tissues (flowers, stems, roots and four developmental leaf stages and the stability of expression was assessed using three algorithms (geNorm, NormFinder and BestKeeper. From our results we conclude that Ec10131 and TPB1 are the most appropriate internal reference genes in leaves (where the majority of cocaine is produced, while Ec10131 and Ec6409 are the most suitable internal reference genes across all of the tissues tested.

  6. Efecto terapéutico del extracto etanólico de Erythroxylum coca spp. en anemia ferropénica inducida en ratas Holtzman macho

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    Evelyn F. Gonzales-Carazas

    2013-01-01

    Full Text Available Introducción: La hoja de coca ha sido usada tradicionalmente con fines medicinales y contiene altos niveles de hierro. Objetivos: Determinar el efecto del extracto etanólico de Erythroxylum coca spp. frente a anemia ferropénica inducida por dieta deficiente en hierro, en ratas Holtzman macho. Diseño: Experimental. Lugar: Laboratorio del Instituto de Patología, Facultad de Medicina, Universidad Nacional Mayor de San Marcos. Material biológico: Dieciocho ratas Holtzman macho de 16 días de edad recién destetadas. Intervenciones: Se formó tres grupos de seis ratas cada uno: a grupo hierro suficiente (HS, recibió 25 g/d de alimento balanceado durante 7 semanas; b grupo hierro deficiente (HD, recibió 25 g/d de dieta ferropénica durante 7 semanas; y, c el grupo hierro deficiente - extracto E. coca (HD-EC, recibió 25 g/d de dieta ferropénica durante 7 semanas y a partir de la semana 5 se agregó 18 g/d de extracto de E. coca. Principales medidas de resultados: Nivel sérico de hemoglobina, peso y talla. Resultados: Al finalizar el tratamiento, se observó aumento significativo de la hemoglobina en el grupo HD-EC (p=0,04. Se encontró diferencia significativa en los niveles séricos de hemoglobina entre los grupos HD-EC y HD (p=0,0062. No se encontró diferencia significativa en los valores de hemoglobina entre los grupos HD-EC y HS (p= 0,06. No se evidenció diferencia en el peso y la talla entre los grupos HD y HD-EC (p=0,20 y p=0,23, respectivamente. Conclusiones: E. coca presenta efecto antianémico experimental, sustentado en los resultados de los niveles de hemoglobina.

  7. Evaluación de sustancias fitoprotectoras usadas como estrategia de neutralización de la acción del glifosato sobre cultivos de erythroxylum coca

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    Carlos Julio Tunjano Huerta

    2011-01-01

    Full Text Available Son múltiples las estrategias empleadas por los cocaleros para resistir a los programas de erradicación. El estudio tuvo como objetivo evaluar 3 tratamientos usados por los cultivadores de coca para neutralizar la acción del glifosato, para tal efecto se estableció un cultivo de coca Erythroylum coca y mediante diseño experimental en bloques al azar se aplicaron los tratamientos consistentes en aspersiones a plantas adultas completamente establecidas (8 meses de edad compuestos en 3 tipos de sustancias disueltas en agua: Melaza 0.1 g/ml., Leche 1 g/ml, Jabón detergente 10 g/l, mediante inspección basada en la escala de ALAM se determinó los signos de toxicidad y la efectividad fitoprotectora de las sustancias empleadas encontrándose la ineficacia de las estrategias.

  8. Social control as supplyside harm reduction strategy The case of an indigenous coca growing community in Peru

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    GARCIA-YI, Jaqueline

    2014-05-01

    Full Text Available Traditional coca uses have taken place in Peru and Bolivia from three thousand years. International organizations have urged the implementation of “zero-coca” growing policies in those countries, although without tangible results. Supply-side harm reduction strategies are currently being implemented in Bolivia, which rely on social control to limit, although not totally abolish coca growing. In this article, the different motivations for traditional coca growing are extensively reviewed, and the data from a survey conducted with 496 farmers in an indigenous community is examined, in order to provide a comprehensive overview of the coca-growing problem and to evaluate if social control could potentially influence the scale of coca growing in Peru. The results suggest that social control variables, such as attachment, involvement, and beliefs, seem to limit coca-growing areas. Those factors have been largely overlooked and may offer an opportunity to reduce coca areas if explicitly considered in anti-drug policy design.

  9. Cytotoxic effect of Erythroxylum suberosum combined with radiotherapy in head and neck cancer cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, Taysa B.C.; Torres, Hianne M.; Yamamoto-Silva, Fernanda Paula; Silva, Maria Alves G. [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Escola de Odontologia; Elias, Silvia T.; Silveira, Damaris; Magalhaes, Perola O.; Lofrano-Porto, Adriana; Guerra, Eliete N.S., E-mail: elieteneves@unb.br [Universidade de Brasilia (UnB), Brasilia, DF (Brazil). Faculdade de Ciencias da Saude

    2016-01-15

    The mouth and oropharynx cancer is the 6{sup th} most common type of cancer in the world. The treatment may involve surgery, chemotherapy and radiotherapy. More than 50% of drugs against cancer were isolated from natural sources, such as Catharanthus roseus and epipodophyllotoxin, isolated from Podophyllum. The biggest challenge is to maximize the control of the disease, while minimizing morbidity and toxicity to the surrounding normal tissues. The Erythroxylum suberosum is a common plant in the Brazilian Cerrado biome and is popularly known as 'cabelo-de-negro'. The objective of this study was to evaluate the cytotoxic activity of Erythroxylum suberosum plant extracts of the Brazilian Cerrado biome associated with radiotherapy in human cell lines of oral and hypopharynx carcinomas. Cells were treated with aqueous, ethanolic and hexanic extracts of Erythroxylum suberosum and irradiated at 4 Gy, 6 Gy and 8 Gy. Cytotoxicity was evaluated by MTT assay and the absorbance was measured at 570 nm in a Beckman Counter reader. Cisplatin, standard chemotherapy, was used as positive control. The use of Erythroxylum suberosum extracts showed a possible radiosensitizing effect in vitro for head and neck cancer. The cytotoxicity effect in the cell lines was not selective and it is very similar to the effect of standard chemotherapy. The aqueous extract of Erythroxylum suberosum, combined with radiotherapy was the most cytotoxic extract to oral and hypopharynx carcinomas. (author)

  10. Cytotoxic effect of Erythroxylum suberosum combined with radiotherapy in head and neck cancer cell lines

    International Nuclear Information System (INIS)

    Macedo, Taysa B.C.; Torres, Hianne M.; Yamamoto-Silva, Fernanda Paula; Silva, Maria Alves G.; Elias, Silvia T.; Silveira, Damaris; Magalhaes, Perola O.; Lofrano-Porto, Adriana; Guerra, Eliete N.S.

    2016-01-01

    The mouth and oropharynx cancer is the 6 th most common type of cancer in the world. The treatment may involve surgery, chemotherapy and radiotherapy. More than 50% of drugs against cancer were isolated from natural sources, such as Catharanthus roseus and epipodophyllotoxin, isolated from Podophyllum. The biggest challenge is to maximize the control of the disease, while minimizing morbidity and toxicity to the surrounding normal tissues. The Erythroxylum suberosum is a common plant in the Brazilian Cerrado biome and is popularly known as 'cabelo-de-negro'. The objective of this study was to evaluate the cytotoxic activity of Erythroxylum suberosum plant extracts of the Brazilian Cerrado biome associated with radiotherapy in human cell lines of oral and hypopharynx carcinomas. Cells were treated with aqueous, ethanolic and hexanic extracts of Erythroxylum suberosum and irradiated at 4 Gy, 6 Gy and 8 Gy. Cytotoxicity was evaluated by MTT assay and the absorbance was measured at 570 nm in a Beckman Counter reader. Cisplatin, standard chemotherapy, was used as positive control. The use of Erythroxylum suberosum extracts showed a possible radiosensitizing effect in vitro for head and neck cancer. The cytotoxicity effect in the cell lines was not selective and it is very similar to the effect of standard chemotherapy. The aqueous extract of Erythroxylum suberosum, combined with radiotherapy was the most cytotoxic extract to oral and hypopharynx carcinomas. (author)

  11. COCA Commentary

    Centers for Disease Control (CDC) Podcasts

    COCA Commentary podcasts are designed to be an educational resource for healthcare providers. This podcast series provides current information on emerging health threats, emergency preparedness and response topics, and CDC clinical guidance.

  12. Control de la cocaína: ¿represión o legalización?

    OpenAIRE

    Cartay, Rafael

    2007-01-01

    Artículos Control de la cocaína: ¿represión o legalización? Cartay, Rafael El presupuesto nacional y la política económica. Contreras C., Hugo de Jesús Viejos y nuevos modelos de Venezuela. Domingo, Carlos; Fargier, María; Mora, C., Jesús Alberto; Rojas Salazar, Andrés y Tonella, Giorgio Una aplicación del análisis de componentes principales en el área educativa. González Martín, Pilar; Díaz de Pascual, Amelia; Torres Lezama, Enrique y Garnica Olmos, Elsy El proces...

  13. Spray droplet size, drift potential, and risks to nontarget organisms from aerially applied glyphosate for coca control in Colombia.

    Science.gov (United States)

    Hewitt, Andrew J; Solomon, Keith R; Marshall, E J P

    2009-01-01

    A wind tunnel atomization study was conducted to measure the emission droplet size spectra for water and Glyphos (a glyphosate formulation sold in Colombia) + Cosmo-flux sprays for aerial application to control coca and poppy crops in Colombia. The droplet size spectra were measured in a wind tunnel for an Accu-Flo nozzle (with 16 size 0.085 [2.16 mm] orifices), under appropriate simulated aircraft speeds (up to 333 km/h), using a laser diffraction instrument covering a dynamic size range for droplets of 0.5 to 3,500 microm. The spray drift potential of the glyphosate was modeled using the AGDISP spray application and drift model, using input parameters representative of those occurring in Colombia for typical aerial application operations. The droplet size spectra for tank mixes containing glyphosate and Cosmo-Flux were considerably finer than water and became finer with higher aircraft speeds. The tank mix with 44% glyphosate had a D(v0.5) of 128 microm, while the value at the 4.9% glyphosate rate was 140 microm. These are classified as very fine to fine sprays. Despite being relatively fine, modeling showed that the droplets would not evaporate as rapidly as most similarly sized agricultural sprays because the nonvolatile proportion of the tank mix (active and inert adjuvant ingredients) was large. Thus, longer range drift is small and most drift that does occur will deposit relatively close to the application area. Drift will only occur downwind and, with winds of velocity less than the modeled maximum of 9 km/h, the drift distance would be substantially reduced. Spray drift potential might be additionally reduced through various practices such as the selection of nozzles, tank mix adjuvants, aircraft speeds, and spray pressures that would produce coarser sprays. Species sensitivity distributions to glyphosate were constructed for plants and amphibians. Based on modeled drift and 5th centile concentrations, appropriate no-spray buffer zones (distance from the

  14. Flavonoides glicosilados de Erythroxylum pulchrum a. st.-hil. (Erythroxylaceae

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    Camila Holanda de Albuquerque

    2014-01-01

    Full Text Available The phytochemical investigation of Erythroxylum pulchrum St. Hil. (Erythroxylaceae led to the isolation of three known flavonoid glycosides quercetin-3-O-α-L-rhaminoside, ombuin-3-ruthinoside and ombuin-3-ruthinoside-5-glucoside. These flavonoids are being described for the first time in this E. pulchrum. The structures of the compounds were determined by analysis of IR, MS and NMR data, as well as by comparison with literature data. The methanolic extract of leaves from E. pulchrum inhibited the growth of the Bacillus subtilis CCT 0516, Escherichia coli ATCC 2536, Pseudomonas aeruginosa ATCC 8027, P. aeruginosa ATCC 25619, Staphylococcus aureus ATCC 6538, S. aureus ATCC 25925, Streptococcus sanguinis ATCC 15300, S. salivarius ATCC 7073, S. mutans ATCC 25175 and Streptococcus ATCC. S. aureus ATCC 25925 was the most sensitive among the other S. sanguinis while S. salivarius proved the most resistant.

  15. Flavonoid glycosides from Erythroxylum pulchrum A. St.-Hil. (Erythroxylaceae)

    International Nuclear Information System (INIS)

    Albuquerque, Camila Holanda de; Tavares, Josean Fechine; Oliveira, Steno Lacerda de; Silva, Taina Souza; Costa, Vicente Carlos de Oliveira; Silva, Marcelo Sobral da; Goncalves, Gregorio Fernandes; Pessoa, Hilzeth de Luna Freire; Agra, Maria de Fatima

    2014-01-01

    The phytochemical investigation of Erythroxylum pulchrum St. Hil. (Erythroxylaceae) led to the isolation of three known flavonoid glycosides quercetin-3-O-α-L-rhaminoside, ombuin-3-ruthinoside and ombuin-3-ruthinoside-5-glucoside. These flavonoids are being described for the first time in this E. pulchrum. The structures of the compounds were determined by analysis of IR, MS and NMR data, as well as by comparison with literature data. The methanolic extract of leaves from E. pulchrum inhibited the growth of the Bacillus subtilis CCT 0516, Escherichia coli ATCC 2536, Pseudomonas aeruginosa ATCC 8027, P. aeruginosa ATCC 25619, Staphylococcus aureus ATCC 6538, S. aureus ATCC 25925, Streptococcus sanguinis ATCC 15300, S. salivarius ATCC 7073, S. mutans ATCC 25175 and Streptococcus ATCC. S. aureus ATCC 25925 was the most sensitive among the other S. sanguinis while S. salivarius proved the most resistant. (author)

  16. Flavonoid glycosides from Erythroxylum pulchrum A. St.-Hil. (Erythroxylaceae); Flavonoides glicosilados de Erythroxylum pulchrum A. St.-Hil. (Erythroxylaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Albuquerque, Camila Holanda de; Tavares, Josean Fechine; Oliveira, Steno Lacerda de; Silva, Taina Souza; Costa, Vicente Carlos de Oliveira; Silva, Marcelo Sobral da, E-mail: josean@ltf.ufpb.br [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Centro de Ciencias da Saude. Departamento de Ciencias Farmaceuticas; Goncalves, Gregorio Fernandes; Pessoa, Hilzeth de Luna Freire [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Centro de Ciencias da Saude. Dept. de Biologica Molecular; Agra, Maria de Fatima [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Centro de Biotecnologia. Departamento de Biotecnologia

    2014-07-01

    The phytochemical investigation of Erythroxylum pulchrum St. Hil. (Erythroxylaceae) led to the isolation of three known flavonoid glycosides quercetin-3-O-α-L-rhaminoside, ombuin-3-ruthinoside and ombuin-3-ruthinoside-5-glucoside. These flavonoids are being described for the first time in this E. pulchrum. The structures of the compounds were determined by analysis of IR, MS and NMR data, as well as by comparison with literature data. The methanolic extract of leaves from E. pulchrum inhibited the growth of the Bacillus subtilis CCT 0516, Escherichia coli ATCC 2536, Pseudomonas aeruginosa ATCC 8027, P. aeruginosa ATCC 25619, Staphylococcus aureus ATCC 6538, S. aureus ATCC 25925, Streptococcus sanguinis ATCC 15300, S. salivarius ATCC 7073, S. mutans ATCC 25175 and Streptococcus ATCC. S. aureus ATCC 25925 was the most sensitive among the other S. sanguinis while S. salivarius proved the most resistant. (author)

  17. Hygrine and cuscohygrine as possible markers to distinguish coca chewing from cocaine abuse in workplace drug testing.

    Science.gov (United States)

    Rubio, C; Strano-Rossi, S; Tabernero, M J; Anzillotti, L; Chiarotti, M; Bermejo, A M

    2013-04-10

    Cocaine abuse is widespread all over the world, and is performed generally by sniffing, injecting or smoking cocaine or crack. The distinction between the recreational use of cocaine from the practice of the so called "coqueo" is still an issue in those countries where this habit is diffused and where it is not considered an addiction, by this reason is necessary to develop a method for to distinguish the coca chewers and cocaine abusers. The use of an unique marker to distinguish between cocaine abuse and chewing of coca leaves is of fundamental importance in those countries where this habit is diffused. Certain alkaloids of the leaves of Erythroxylum coca are lost during the process of extraction/purification of cocaine and it is not possible to find them neither in seizures of chlorhidrate of cocaine nor urine samples of cocaine abusers. These markers are the hygrine and cuscohygrine that are present in the leaves of E. coca. A fast GC/MS method involving a liquid:liquid extraction procedure with tertbutylmethylether (TBME) is proposed for the determination of some alkaloids in cocaine leaves, cocaine seizures and biological samples. All specimens were alkalinized to pH 9 with a carbonate/bicarbonate buffer and then extracted with TBME. The analysis was carry out by GC/MS with electron impact at 70 eV and in full scan mode. The results demonstrate that hygrine and cuscohygrine are not found neither in the urine of cocaine abusers nor in cocaine seizures. For this reason this compounds could be considered as markers of coca chewing. This developed method permits to distinguish coca chewing from cocaine abuse in workplace drug testing through the analysis of urine samples. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  18. Hjernen vil have Coca Cola

    DEFF Research Database (Denmark)

    Jantzen, Christian

    2008-01-01

    Coca Cola kan i modsætning til Pepsi aktivere den præfontale kortex eller pandelappen - derfor er det selvfølgelig den, vi vil have!......Coca Cola kan i modsætning til Pepsi aktivere den præfontale kortex eller pandelappen - derfor er det selvfølgelig den, vi vil have!...

  19. Philanthropically Always Coca-Cola.

    Science.gov (United States)

    Black Issues in Higher Education, 1997

    1997-01-01

    In an interview, the head of the Coca-Cola Foundation, Ingrid Saunders Jones, discusses the foundation's objectives for financial support of education and the role of targeted and ethnic marketing, programs at historically black colleges and universities, recent growth of the endowment, number of projects funded, and the role of the Coca-Cola…

  20. Intoxicação por Erythroxylum deciduum (Erythroxylaceae em ovinos Poisoning by Erythroxylum deciduum (Erythroxylaceae in sheep

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    Edson Moleta Colodel

    2004-09-01

    Full Text Available Este trabalho descreve os aspectos epidemiológicos, clínicos e patológicos da intoxicação natural pelos frutos de Erythroxylum deciduum ("cocão" em ovinos, que ocorreu de janeiro a março de 2004, no município de Lagoa Vermelha, RS. A doença foi reproduzida pela administração dos frutos de E. deciduum por via oral a 5 ovinos. Destes, três adoeceram e morreram. Os frutos de E. deciduum foram tóxicos em dose única de 60g/kg ou quando fracionado em pelo menos 4 doses de 17 g/kg a cada 12 horas. Os principais sinais clínicos nos animais intoxicados natural e experimentalmente, foram neurológicos e caracterizados por ataxia, hiperexcitabilidade e tremores musculares que se pronunciavam durante o manejo. Próximo à morte, os ovinos apresentavam dispnéia com respiração abdominal e cianose. Na necropsia as alterações mais importantes, em 6 casos de intoxicação espontânea e os 3 ovinos experimentalmente intoxicados, foram edema e congestão pulmonar acentuada e a presença de frutos ou sementes de E. deciduum no conteúdo ruminal. Histologicamente, exceto edema e congestão pulmonar, não foram encontradas outras alterações significativas.The epidemiological, clinical and pathological aspects of natural poisoning caused by Erythroxylum deciduum fruits in sheep are reported. The outbreak occurred from January to March of 2004, in Lagoa Vermelha county, state of Rio Grande do Sul, Brazil. The poisoning was experimentally reproduced by oral administration of E. deciduum fruits to 5 sheep.Three of them developed neurological signs and died. Poisoning was caused with a single dose of 60g/kg or when the dosage was fractioned into at least 4 doses of 17 g/kg given every 12 hours. The main clinical signs in natural and experimentally poisoned sheep were ataxia, hyperexcitability and muscular tremors which where more pronounced when the animals were moved. At the final stage, dyspnea with abdominal breathing and cyanosis was observed

  1. From Conflict to Collaboration: An Innovative Approach to Reducing Coca Cultivation in Bolivia

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    Kathryn Ledebur

    2013-03-01

    Full Text Available Upon his presidential election, Bolivian coca grower leader Evo Morales adopted a policy of promoting consensual coca reduction through social control, a sophisticated coca monitoring system, and economic development. That strategy is paying off. In 2011, coca cultivation decreased by 13 per cent according to the U.S. government. The Morales administration has also made significant progress facing the ongoing challenges of drug production and trafficking. Seizures of coca paste and cocaine and destruction of drug laboratories have steadily increased since President Morales took office. Despite continued tensions in bilateral relations, U.S.-Bolivian counter-drug cooperation continues and the signing of a new framework agreement in 2011 should lead to an exchange of ambassadors. Internationally, Bolivia has successfully gained acceptance of the right to the traditional use of coca within its own territory. But Bolivia’s efforts must be carried out in tandem with effective demand reduction strategies to shrink the global cocaine market.

  2. Transtornos mentais como fatores de risco para o desenvolvimento de abuso/dependência de cocaína: estudo caso-controle Mental disorders as risk factors for the development of cocaine abuse/dependence: case-control study

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    Claudia S Lopes

    1999-10-01

    Full Text Available OBJETIVO: Avaliar o papel dos transtornos mentais e da dependência ao álcool como possíveis fatores de risco para o abuso/dependência de cocaína. MÉTODOS: Utilizou-se o desenho caso-controle e a técnica de bola-de-neve (snowball technique para selecionar uma amostra de usuários de cocaína não tratados na comunidade (casos e parear casos e controles por sexo, idade e amizade. A coleta de dados foi feita através da utilização do questionário CIDI (Composite International Diagnostic Interview que gera diagnósticos de acordo com os critérios do Diagnostic and Statistical Manual of Mental Disorders-III-R. A análise dos dados foi feita através de regressão logística condicional. RESULTADOS: O estudo incluiu 208 indivíduos. Os principais resultados mostraram que história passada de dependência ao álcool era o principal fator associado a um aumento no risco de desenvolvimento de abuso de cocaína (OR=15,1; IC 95% 3,8-60,2; nenhum outro transtorno mental isolado manteve-se significativamente associado ao aumento deste risco após a análise multivariada. Aumento no risco de abuso de cocaína também foi encontrado entre os indivíduos que relataram pensamentos suicidas (OR=3,1; IC 95% 0,91-10,8, sugerindo associação entre quadros mais graves de depressão e abuso de cocaína. CONCLUSÕES: Esses achados sugerem que os programas voltados para a prevenção e tratamento do abuso de cocaína devem estar preparados para o manejo de questões relacionadas à co-morbidade do abuso de drogas com o álcool e outros distúrbios psiquiátricos.OBJECTIVE: To evaluate the role of psychiatric disorders and alcohol dependence as possible risk factors for cocaine abuse/dependence. METHODS: The case-control study used the "snowball" technique in order to select untreated cocaine users (cases and to match sex, age and friendship. Information was gathered using the Composite International Diagnostic Interview (CIDI, and computer diagnosis were

  3. Evaluation of heavy metals in the process of composting organic waste of coca leaves

    Directory of Open Access Journals (Sweden)

    Apaza-Condori Emma Eva

    2015-11-01

    Full Text Available The present study is to evaluate the total concentrations of the heavy metals in waste compost samples from coca leaf. This work was carried out Kallutaca Experimental Center, Biofertilizers module Career Agricultural Engineering at the Public University of El Alto, La Paz municipality of Laja. Posed treatments were: T1 (+ Yogurt Coca wastes; T2 (Coca wastes + whey; T3 (Coca wastes + yeast and T4 (Control. The design was completely randomized with 4 treatments and 3 repetitions. The concentration of heavy metals (cadmium, copper, nickel, lead, mercury and chromium; they were categorized into Class A, for the four treatments according to the classifications established by Moreno & Moral (2008.

  4. Preference of stevia level in Coca Cola

    DEFF Research Database (Denmark)

    Panovská, Zdenka; Grosová, Stanislava; Sudzina, Frantisek

    2017-01-01

    Coca Cola Life was first introduced in Argentina in June 2013. In the following 15 months, it was launched also in Chile, Sweden, and the U.K. Since January 2015, it is available in many but not all countries. In the version of Coca Cola Life, which was produced till December 2016, 35% of sugar...... was replaced by stevia. In the version produced since January 2017, 45% of sugar is replaced by stevia. This opened a limited time-frame for studying preferences between regular Coca Cola, Coca Cola Life with 35% of stevia, and Coca Cola Life with 45% of stevia. The aim of the paper is to investigate if Big...... Five Inventory personality traits, gender, age, smoking, and drinking of any cola in general influence preferred amount of stevia. The research was conducted in the Czech Republic where Coca Cola Life is not available, so all respondents are equally unaware of (or equally not used to) the taste. All...

  5. Coca-Cola’s case

    OpenAIRE

    Fabregat García, Noelia

    2015-01-01

    Treball final de Grau en Finances i Comptabilitat. Codi: FC1049. Curs acadèmic 2014-2015 Coca-Cola’s case is a research paper based on cocacola bottling companies in Spain. Its aim is to analyse its financial statements and the conclusions about its corresponding profitability and liquidity indicators to finally reach the conclusion that this large reorganizations and the labour force adjustment plan suffered were not really argued and the alleged causes were not certa...

  6. Pepsi und Coca ewige Rivallen

    OpenAIRE

    POLJAKOW ANDREJ; POLJAKOW WLADIMIR

    2016-01-01

    Fast jeder kennt Pepsi und Coca. Man kann sie treffen praktisch in jedem Geschaeft. Dennoch nicht alle wissen, dass diese Firmen Erzrivallen sind und das ihre Rivallitaet sich seit Ewigkeit dauert. In meinem Artikel, welches ich in der Zusammenarbeit mit meinem Vater schrieb versuchte ich den Weg beider Firmen von der Gruendung bis heutigen Tagen zu beschreiben. Auf diesem Weg trafen sich technologische Aenderungen, Gerichtsverhandlungen, sowie geschickte Tricks. Wichtige Rolle spielt auch Ma...

  7. Coca-Cola's Many faces

    OpenAIRE

    Nicholson, Kasper

    2014-01-01

    This reports has been written with the purpose to answer how are the semiotic choices used in advertising on the official website of Coca-Cola, both in Japan and in the US, be argued to create a different meaningful whole to guide their respective target audiences, which share characteristics with ‘John’ and ‘Kyo’, to the preferred reading. Coming from different cultural backgrounds, particularly high vs low context cultures, ‘John’ and ‘Kyo’ create meaning from the collaboration of the signs...

  8. Protective Effect of the Plant Extracts of Erythroxylum sp. against Toxic Effects Induced by the Venom of Lachesis muta Snake

    Directory of Open Access Journals (Sweden)

    Eduardo Coriolano de Oliveira

    2016-10-01

    Full Text Available Snake venoms are composed of a complex mixture of active proteins that induce toxic effects, such as edema, hemorrhage, and death. Lachesis muta has the highest lethality indices in Brazil. In most cases, antivenom fails to neutralize local effects, leading to disabilities in victims. Thus, alternative treatments are under investigation, and plant extracts are promising candidates. The objective of this work was to investigate the ability of crude extracts, fractions, or isolated products of Erythroxylum ovalifolium and Erythroxylum subsessile to neutralize some toxic effects of L. muta venom. All samples were mixed with L. muta venom, then in vivo (hemorrhage and edema and in vitro (proteolysis, coagulation, and hemolysis assays were performed. Overall, crude extracts or fractions of Erythroxylum spp. inhibited (20%–100% toxic effects of the venom, but products achieved an inhibition of 4%–30%. However, when venom was injected into mice before the plant extracts, hemorrhage and edema were not inhibited by the samples. On the other hand, an inhibition of 5%–40% was obtained when extracts or products were given before venom injection. These results indicate that the extracts or products of Erythroxylum spp. could be a promising source of molecules able to treat local toxic effects of envenomation by L. muta venom, aiding in the development of new strategies for antivenom treatment.

  9. Brandimielikuvan muodostuminen : case: Coca-Cola

    OpenAIRE

    Mollberg, Janina; Helén, Rea

    2009-01-01

    Tutkimuksen tarkoituksena oli selvittää Coca-Cola-virvoitusjuoman brandimielikuvia suhteessa yläasteikäisten ostokäyttäytymiseen ja verrata saatuja tuloksia Coca-Cola-virvoitusjuoman asettamiin mielikuvatavoitteisiin ja brandin saavuttamaan laajaan suosioon. Tämän ohella toisena ongelmana oli tutkia sitä, minkä tekijöiden perusteella 7.-9.-luokkalaisten mielikuvat nuorten keskuudessa eroavat toisistaan. Lisäksi haluttiin pohtia, miksi yläasteikäiset ostavat Coca-Cola-virvoitusjuomaa. Tutkimuk...

  10. [Phytobezoar dissolution with Coca-Cola].

    Science.gov (United States)

    Martínez de Juan, F; Martínez-Lapiedra, C; Picazo, V

    2006-05-01

    The treatment of phytobezoar is empiric. The various therapeutic choices include dietary modifications, prokinetic drugs, gastric lavage, enzymatic dissolution, endoscopic treatment, and surgery. We present two cases of phytobezoar with successful outcome after Coca-Cola administration.

  11. BRANDS AND BRANDING - EXAMPLE: COCA-COLA

    Directory of Open Access Journals (Sweden)

    Ljiljana Stošić Mihajlović

    2013-01-01

    Full Text Available The most valuable brand in the world is still "Coca Cola", and the highest increase was recorded value "Apple" because that's who entered the top ten most valuable brands. Coca-Cola HBC Serbia makes a significant contribution to the local economy. In three bottling plants, distribution centers and sales offices in Serbia and employ over 1500 people. Taxes that are paid regularly Serbian authorities are yet another way of contribution to the national economy.

  12. BRANDS AND BRANDING - EXAMPLE: COCA-COLA

    OpenAIRE

    Ljiljana Stošić Mihajlović

    2013-01-01

    The most valuable brand in the world is still "Coca Cola", and the highest increase was recorded value "Apple" because that's who entered the top ten most valuable brands. Coca-Cola HBC Serbia makes a significant contribution to the local economy. In three bottling plants, distribution centers and sales offices in Serbia and employ over 1500 people. Taxes that are paid regularly Serbian authorities are yet another way of contribution to the national economy.

  13. Development of anthers and pollen in Brazilian heterostylic species of Erythroxylum (Erythroxylaceae): an ecological approach

    International Nuclear Information System (INIS)

    Silva, L.D.; Fernandes, C. L.

    2016-01-01

    This study describes the development of anthers and pollen in heterostylic flowers of two species of Erythroxylum. The features of anthers and their developmental pattern, which is of the dicotyledonous type, do not vary according to morphs or species. The pollen grains of both morphs show differences in their morphology, development, and content stored as a reserve source. In both species, thrum (short-styled) flowers presented bicellular pollen grains, while pin (long-styled) ones yielded bi- and tricellular pollen grains. The presence of inviable pollen grains in the two flower morphs of both species and the malformation of one of the four microsporanges in the thrum flowers of E. campestre are noteworthy. We verified that features found both in the anther wall and in the pollen grains could be related to the reproductive success and adaptation of the species to the Brazilian savanna biome. (author)

  14. Condoms and Coca-Cola.

    Science.gov (United States)

    Townsend, S

    1992-01-01

    Social marketing entails promoting the appropriate and quality product to be sold in the right places at the right price. Even though mass media advertisement of condoms is forbid in Zaire, condoms have been effectively promoted and sold in the country using alternate approaches. 8 million units of the condom, Prudence, were sold in 1990, and Prudence has become the generic name for condoms in the Zaire. Noting that Coca-Cola, beer, and cigarettes may be purchased virtually ubiquitously, commercial outlets and local traders were enlisted to sell condoms at reduced prices on the market. Reduced price sales are possible since donor and government agencies provide the condoms to wholesalers and merchants free of charge. The successful social marketing of condoms expands condom availability to a greater segment of a country's population while recovering some public sector costs and shifting health care away from the public sector. Condoms are especially promoted to high risk groups such as commercial sex workers and their clients in Zaire. Similar programs have been inspired in 10 African countries including Cameroon and Burundi, as well as in Brazil, Haiti, and India. Prevention programs in Latin America and Asia will benefit from these program experiences in Africa. In closing, the article notes the need for an adequate and predictable commodity supply in attaining effective social marketing. Marked program success may, however, lead to sustainability problems.

  15. No harmful effect of different Coca-cola beverages after 6 months of intake on rat testes.

    Science.gov (United States)

    Tóthová, Lubomíra; Hodosy, Július; Mettenburg, Kathryn; Fábryová, Helena; Wagnerová, Alexandra; Bábíčková, Janka; Okuliarová, Monika; Zeman, Michal; Celec, Peter

    2013-12-01

    Our laboratory recently reported that a 3-month exposure of rats to cola-like beverages induced sex hormone changes. The aim of the study was to investigate the effects of various types of Coca-cola intake with different composition for 6 months on oxidative status in testes and testosterone in adult male rats. Fifty adult male Wistar rats were divided into control group drinking water, and groups drinking different Coca-cola beverages (regular Coca-cola, Coca-cola caffeine-free, Coca-cola Light and Coca-cola Zero). Oxidative and carbonyl stress markers were measured in the testicular tissue to assess oxidative status together with testicular and plasma testosterone. StAR expression in testes as a marker of steroidogenesis was quantified. No significant differences were found between the groups in any of the measured parameters. In conclusion, oxidative and carbonyl stress in testicular tissue were not influenced by drinking any type of Coca-cola. Additionally, testosterone in testes and in plasma, as well as testicular StAR expression were comparable among the groups. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. CUSTOMER RELATIONSHIP MANAGEMENT : case study Coca-Cola Company

    OpenAIRE

    Ling, Xiaojing

    2017-01-01

    The Coca-Cola Company is an American multinational beverage corporation, a manufacturer, retailer and marketer of non-alcoholic beverage concentrates and syrups with its headquarter in Atlanta, Georgia. This thesis is aimed to affirm the superiority of the Coca-Cola Company and to find out its shortcomings in managing customer relationships based on studying the customer relationship management strategy for Coca-Cola Company and discussing the comparison between Coca-Cola and Pepsi Cola, then...

  17. Composting system for waste treatment coca leaf with the addition of three biological activators in the Experimental Center Kallutaca

    Directory of Open Access Journals (Sweden)

    Apaza-Condori Emma Eva

    2015-11-01

    Full Text Available The objective of this study was to evaluate the composting process waste coca leaf with the addition of three biological activators (yogurt, whey and yeast. This work was carried out Kallutaca Experimental Center, Biofertilizers module Career Agricultural Engineering at the Public University of El Alto, La Paz municipality of Laja. Posed treatments were: T1 (+ Yogurt Coca wastes; T2 (Coca wastes + whey; T3 (Coca wastes + yeast and T4 (Control. The design was completely randomized with 4 treatments and 3 repetitions. The values in N are classified medium and high levels the quantities of P, K are classified as middle levels. The value obtained 7.9 pH, EC 12950 µS/cm and 61% organic matter belong to treatment T1. The decomposition time was a period of 105 days corresponds to treatment T3.

  18. [Effects of coca chewing on the glucose tolerance test].

    Science.gov (United States)

    Galarza Guzmán, M; Peñaloza Imaña, R; Echalar Afcha, L; Aguilar Valerio, M; Spielvogel, H; Sauvain, M

    1997-01-01

    The effects of coca chewing on the glucose tolerance test were measured. The subjects were 14 habitual coca chewers and 14 non-chewers. All were of Aymara ancestry and came from a rural community from the "Altiplano" close to the city of La Paz. The coca users chewed coca leaves during 3 1/2 hours of the test. The non-chewers showed a significant hypoglycemia at 120 minutes of the test. This effect was not observed in the coca chewers. The hormonal counter-regulation response to hypoglycemia worked perfectly in non-chewers, since glucose levels reached normal values at 180 minutes of the test. These results suggest that coca chewers, at high altitude do not present hypoglycemia, due to an antagonic action of coca metabolites on insulin; allowing a greater availability of glucose in the organism. This would have a positive effect on metabolism in an environment of hypobaric hypoxia, known to lead to situations of hypoglycemia.

  19. The use of coca: prehistory, history, and ethnography.

    Science.gov (United States)

    Stolberg, Victor B

    2011-01-01

    The purpose of this article is to review the use of the natural mild stimulant coca, which is a story that originates with the prehistory of coca, evolves through its following historical uses, and leads up to the eventual development of cocaine. This discussion will begin with the botanical background of the coca plant, followed by a review of some of the prehistoric, historic and ethnographic evidence of coca use, which indicates the extensive antiquity and pervasiveness of coca use in South and Central America. The diverse roles that coca played among the Inca and other indigenous peoples led to the early adoption of coca in the West and, in turn, to the resultant discovery of cocaine and its assorted early applications, particularly for medicinal purposes. Copyright © Taylor & Francis Group, LLC

  20. Hardness of enamel exposed to Coca-Cola and artificial saliva.

    Science.gov (United States)

    Devlin, H; Bassiouny, M A; Boston, D

    2006-01-01

    The purpose of this study was to determine the rate of change in indentation hardness of enamel in permanent teeth exposed to Coca-Cola. In a further experiment, the ability of a commercially available artificial saliva to remineralize enamel treated with Coca-Cola was tested. Ten enamel specimens were randomly chosen to be treated with Coca-Cola (experimental groups) and seven with water (control group). The fluids were applied for 1, 2, 3 h and overnight (15 h), washed off with a few drops of water and the moist enamel indentation hardness tested after each interval. With Coca-Cola treatment, the mean enamel hardness was 92.6% (s.d. = 7.9) of the original baseline hardness after 1 h, 93.25% (s.d. = 10.15) after 2 h, 85.7% (s.d. = 12.03) after 3 h and 80.3% after 15 h. The mean indentation hardness of control specimens treated with water was 108.7% (s.d. = 16.09) of the original hardness after 1 h, 99.09% (s.d. = 18.98) after 2 h, 98.97% (s.d. =11.24) after 3 h and 98.42% (s.d. = 22.78) after 15 h. In a separate experiment, the hardness of 9 enamel specimens was tested, as previously described, before and after treatment with Coca-Cola overnight and again after application of artificial saliva for 3 min. Coca-Cola reduced the mean indentation hardness of enamel in the teeth, but the hardness was partially restored with artificial saliva (Salivart) and increased by 18% from the demineralized enamel hardness.

  1. Seasonal variation in gas exchange by plants of Erythroxylum simonis Plowman

    Directory of Open Access Journals (Sweden)

    João Everthon da Silva Ribeiro

    2018-02-01

    Full Text Available ABSTRACT Erythroxylum simonisis an understory species found in Northeast Brazil. Due to its shaded habitat,E. simonisis subjected to seasonal oscillations of the environment, to which it must respond ecophysiologically. The objective of this study was to evaluate the effects of seasonality on the ecophysiology ofE. simonis in a fragment of Seasonal Semideciduous Forest. Leaf area index, visible sky fraction and photosynthetically active radiation were measured for 10 individuals during the dry and rainy seasons. Soil moisture, temperature and monthly precipitation were measured, as well as photosynthetic rate, stomatal conductance, internal CO2concentration, transpiration, instantaneous water use efficiency, instantaneous carboxylation efficiency and chlorophyll content. Ecophysiological variables were correlated with environmental variables, with a greater association of rainfall and soil moisture with stomatal conductance, transpiration and photosynthetic rate, indicating that water availability has an effect on the ecophysiology ofE. simonis. With the exception of instantaneous carboxylation efficiency, gas exchange exhibited significant differences among the months studied, with the highest values being for months with greater water availability, thus showing that the ecophysiology of the species responds to seasonal changes throughout the year.

  2. Edge effect and phenology in Erythroxylum tortuosum (Erythroxylaceae), a typical plant of the Brazilian Cerrado.

    Science.gov (United States)

    Ishino, M N; De Sibio, P R; Rossi, M N

    2012-08-01

    The edge of a forest fragment can be considered a zone of transition between the interior of the fragment and the surrounding habitat matrix. Plants along the edge are more exposed to disturbance and microclimate variation than interior plants, resulting in the so-called edge effect. In this study, we compared leaf area, fluctuating asymmetry and chemical (water, nitrogen and tannins) leaf traits between Erythroxylum tortuosum plants inhabiting the edge with those growing in the interior of a cerrado fragment in Brazil. We also describe the temporal variation in the vegetative and reproductive phenological events of E. tortuosum plants throughout the season. Nitrogen, leaf area and fluctuating asymmetry did not differ between the two plant groups. Young leaves of the edge plants had significantly higher levels of tannins and lower levels of water than those of interior plants. We suggest that differences in leaf chemical concentrations between edge and interior plants may occur due to factors such as light intensity, wind, temperature and leaf age rather than plant stress. With respect to plant phenology, most reproductive events occurred during the spring. Leaf buds and young leaves prevailed during the rainy season. In the dry season, however, the vegetative events decreased due to leaf senescence followed by leaf abscission.

  3. Fiebre del oro blanco: la cocaína

    Directory of Open Access Journals (Sweden)

    Iván Marín Argüello

    1999-12-01

    Full Text Available La planta de coca, Erythroxylon coca es cultivada en la zona occidental de América del Sur exigiendo condiciones de suelo muy particulares. La mezcla de las hojas de cocaína con sustancias químicas origina un polvo cristalino blanco, conocido comúnmente como cocaína. Al producto obtenido del tratamiento de la cocaína con solventes se le denomina crack. El consumo de cocaína, las formas de administración más diversas y el estado fisiológico logrado por los usuarios, es denominado flash 0 high Los efectos neuro-fisiológicos son muy variados, provocando sobre todo un fuerte estímulo al Sistema Nervioso Central (SNC, producto de la liberación de dopamina en las terminaciones nerviosas.

  4. The Coca-Cola Company : equity valuation

    OpenAIRE

    Santos, André Escoval dos

    2015-01-01

    The present dissertation aims to demonstrate the process of valuing The Coca-Cola Company (KO). Valuation is not an exact science, requiring numerous assumptions and different models to be trusted. Several theories and articles from prestigious authors were followed aiming to deliver the best possible result. There is not a consensus among authors about which method yields best results, however Discounted Cash Flow is considered the finest by most of them. Therefore, KO will...

  5. COCA-COLA FINLAND – KALUSTESUUNNITELMA UUSIIN TOIMITILOIHIN

    OpenAIRE

    Luoti, Emilia

    2010-01-01

    Coca-Cola Finland muutti vanhoista tiloistaan Helsingistä Sinebrychoffin tehtaalle Keravalle. Uusista tiloista haluttiin tyylikkäät ja brandin mukaiset, sillä tiloissa vierailee myös asiakkaita. Coca-Cola Finlandin uusien toimitilojen suunnittelussa yrityksen brandin huomioiminen onkin ollut tärkeää. Suunnitelmassa on keskitytty mittatilaus kalusteiden suunnitteluun, mutta työ sisältää myös visuaalisien elementtien suunnittelua. Suunnitteluprosessin aikana on tutkittu Coca-Colaa yritykse...

  6. Fallstudie SIG - Supply Chain Prototyp mit Coca Cola Beverages

    OpenAIRE

    Senger, Enrico

    2003-01-01

    SIG, ein führender Lieferant von Verpackungsmaterialien für Getränke, hat mit Coca Cola CPFR, collaborative planning, forecasting and replenishment realisiert. Das Unternehmen kann elektronisch und ohne Zeitverzug (vorher mit bis zu 15 Tagen Verspätung) auf die Lagerbestände und Verkaufsvorhersagen bei Coca Cola zugreifen. Coca Cola erhält die exakten Liefermengen und zeiten. Coca Cola konnte dadurch den Lagerbestand von Verpackungsmaterial um 50% senken. Dies reduziert die Bearbeitungszeit d...

  7. Perbandingan Kadar Glukosa Darah Setelah Mengonsumsi Coca-cola Reguler Dan Coca-cola Zero Pada Populasi Non-diabetes

    OpenAIRE

    Hutapea, Gabriella Carolina; Ariosta, Ariosta; Hardian, Hardian

    2016-01-01

    Latar belakang : Diabetes melitus (DM) tipe II dan obesitas merupakan penyakit metabolik yang disebabkan oleh sejumlah faktor gaya hidup diantaranya adalah aktivitas fisik, merokok, konsumsi alkohol, pola diet. Coca-cola merupakan salah satu minuman yang digemari dan mengandung tinggi karbohidrat yang diduga meningkatkan risiko obesitas dan kejadian DM tipe II. Coca cola zero merupakan solusi yang diberikan oleh coca cola untuk mengurangi peningkatan glukosa darah.Tujuan : Mengetahui perbedaa...

  8. Influence of an acidic beverage (Coca-Cola) on the absorption of itraconazole.

    Science.gov (United States)

    Jaruratanasirikul, S; Kleepkaew, A

    1997-01-01

    To evaluate the effectiveness of Coca-Cola in enhancing the absorption of itraconazole. Eight healthy volunteers were randomized to receive two treatment sequences in a two-way crossover design with a 1-week wash-out period separating each study treatment. Treatment 1, the control, consisted of 100 mg itraconazole with 325 ml water. Treatment II was identical to treatment I, except that itraconazole was administered with 325 ml of Coca-Cola (pH 2.5). Serum itraconazole concentrations, after administration with Coca-Cola (treatment II), were higher than after administration with water (treatment I). The mean AUC was 1.12 vs 2.02 micrograms.h.m1-1, the mean Cmax was 0.14 vs 0.31 micrograms.m1-1 and the mean tmax was 2.56 vs 3.38 h in treatments I and II, respectively. The absorption of itraconazole can be enhanced by Coca-Cola.

  9. "Coca got us here and now it's our weakness:" Fusarium oxysporum and the political ecology of a drug war policy alternative in Bolivia.

    Science.gov (United States)

    Pearson, Zoe

    2016-07-01

    A strain of Fusarium oxysporum fungus is killing coca plants in the Chapare coca growing region of Bolivia. Coca farmers are already constrained in the amount of coca they can grow under the government's community-based coca control approach, "social control." Coca leaf is the main ingredient in cocaine, but it is also a traditional medicine and food, is economically vital to household incomes, and is a political symbol of the current government administration. Bolivia's approach to coca control, now administered without any United States military intervention, is an innovative example of experimentation with drug policy reform. This paper is based on ethnographic research including semi-structured interviews and observation. Coca growers are worried about the dire economic, social, and political consequences of the fungus' appearance and spread since summer 2013. They have two explanations for its origins: First, that it was sent by the United States government, which in the past was developing a strain of F. oxysporum for use in the drug war; Second, and the explanation of scientists, is that the outbreak is caused by the overuse of agrochemicals and other intensive agricultural practices. More than a matter of agroecology, the practices identified in the second explanation must be understood in terms of the persistence of the international drug prohibition regime. Bolivia's social control approach is a successful alternative to violent eradication measures, however the country is constrained to uphold the fundamental principles of supply-side control in order to be a respected partner in global drug control. The supply-side logics restricting social control make intensive agriculture practices attractive, but may have contributed to the fungus' proliferation and its continued spread. The fungus draws attention to the challenges of policy reform, new collateral damages of drug control, and role environmental factors can play in drug control politics. Copyright

  10. Coca-Cola Hispanic Education Fund: Los Angeles Program Description.

    Science.gov (United States)

    Coca Cola Bottling Co. of Los Angeles, CA.

    The Coca-Cola Hispanic Education Fund was created in response to the high school dropout problem in Los Angeles. The Fund enables the Coca-Cola Bottling Company of Los Angeles to build upon the successful relationship it has developed in the Hispanic community and maximizes the effectiveness of existing student support programs by directing needy…

  11. Erythroxylum pungens elicits vasorelaxation by reducing intracellular calcium concentration in vascular smooth muscle cells of rats

    Directory of Open Access Journals (Sweden)

    Aurylene C. Oliveira

    2012-01-01

    Full Text Available The cardiovascular effects elicited by the ethanolic extract obtained from the roots of Erythroxylum pungens O.E. Schulz, Erythroxylaceae (EEEP and the vasorelaxant effect induced by its main tropane alkaloid (pungencine were investigated. In normotensive rats, administration of EEEP (1, 10, 30 and 60 mg/kg i.v., randomly produced dose-dependent hypotension (-2±1, -7±0.5 -17.6±1, -24±1 Δ mmHg, n=5 followed by tachycardia (3±0.5, 7±2, 7.1±1, 10±5 Δ bpm, n=5. In intact phenylephrine (Phe, 10 µM-pre-contracted rings, EEEP (0.01-500 µg/mL induced concentration-dependent vasorelaxation (EC50 13.7±5.5 µg/mL, Maximal Response= 92±2.6%, and this effect was unchanged after the removal of the vascular endothelium (EC50 27.2±4.7 µg/ml, Maximal Response= 88.3±3.3 %. In KCl (80 mM-pre-contracted-endothelium-denuded rings, EEEP elicited concentration-dependent relaxation (EC50= 128.2±11.2 µg/mL, Maximal Response 76.8±3.4%. Vasorelaxation has also been achieved with tonic contractions evoked by the L-type Ca2+ channel agonist Bay K 8644 (EC50 80.2±9.1 µg/mL, Maximal Response 86.3±8.3%. In addition, in a depolarizing medium, EEEP inhibited CaCl2 (30-500 µg/mL induced contractions and caused a concentration-dependent rightward shift of the relaxation curves. Lastly, the tropane alkaloid pungencine caused vasorelaxation in mesenteric arteries resembling to the EEEP responses. These results suggests that EEEP induces hypotension and vasorelaxation, at least in part, due to the reduction in [Ca2+]i in vascular smooth muscle cells.

  12. Las artes de leer e interpretar las hojas de coca

    Directory of Open Access Journals (Sweden)

    Eugenia Flores

    2017-03-01

    Full Text Available En este artículo quisiera hablar sobre un oficio secreto, subterráneo, clandestino, que es el arte de leer e interpretar las hojas de coca en espacios marginales del valle de Salta. Muestro en estas páginas las diferentes formas y modos en que la coca es utilizada por la población local, diversa y heterogénea, donde tradiciones indígenas ancestrales se manifiestan en prácticas concretas que rozan los límites entre la magia y la terapia. Presto especial interés, a partir del trabajo de campo realizado, a aquellas personas que manejan estas artes de leer las hojas de coca, las cuales en los casos analizados fueron adquiridas a partir de un ritual de paso, que fue el haber sido “tocado por el rayo”. Me interesa particularmente trabajar con estos hombres y mujeres, cuyo arte de hacer con coca es equiparable a las “maneras de hacer”. Estas maneras de hacer con la coca ritual no están visibilizadas y son subterráneas, marginales y silenciosas, en este artículo se pretende dar cuenta de estas prácticas con coca y sus dinámicas relaciones inter e intra comunales. Palabras-claves: Artes; maneras de hacer; coca; ritual.

  13. Coca-Cola - a model of transparency in research partnerships? A network analysis of Coca-Cola's research funding (2008-2016).

    Science.gov (United States)

    Serôdio, Paulo M; McKee, Martin; Stuckler, David

    2018-06-01

    To (i) evaluate the extent to which Coca-Cola's 'Transparency Lists' of 218 researchers that it funds are comprehensive; (ii) map all scientific research acknowledging funding from Coca-Cola; (iii) identify those institutions, authors and research topics funded by Coca-Cola; and (iv) use Coca-Cola's disclosure to gauge whether its funded researchers acknowledge the source of funding. Using Web of Science Core Collection database, we retrieved all studies declaring receipt of direct funding from the Coca-Cola brand, published between 2008 and 2016. Using conservative eligibility criteria, we iteratively removed studies and recreated Coca-Cola's transparency lists using our data. We used network analysis and structural topic modelling to assess the structure, organization and thematic focus of Coca-Cola's research enterprise, and string matching to evaluate the completeness of Coca-Cola's transparency lists. Three hundred and eighty-nine articles, published in 169 different journals, and authored by 907 researchers, cite funding from The Coca-Cola Company. Of these, Coca-Cola acknowledges funding forty-two authors (Coca-Cola Company appears to have failed to declare a comprehensive list of its research activities. Further, several funded authors appear to have failed to declare receipt of funding. Most of Coca-Cola's research support is directed towards physical activity and disregards the role of diet in obesity. Despite initiatives for greater transparency of research funding, the full scale of Coca-Cola's involvement is still not known.

  14. Efectividad del uso del mate de coca en la reducción del estrés laboral en

    OpenAIRE

    Rivera-Encinas, María Teresa

    2016-01-01

    Objetivo: Evaluar la efectividad del uso del mate de coca en la reducción del estrés laboral en administrativos de una universidad y determinar sus principales características sociodemográficas.Material y métodos: Se aplicó el cuestionario para la detección del estrés laboral de la OIT/OMS a dos grupos de trabajadores, experimental (10) y control (10), empleando randomización simple. Se hizo un experimento cruzado en 31 días, utilizando mate de coca y agua para cada grupo. Se utilizó el análi...

  15. Analysis of Marketing Strategy of Coca-Cola Company

    Institute of Scientific and Technical Information of China (English)

    刘燕华

    2017-01-01

    This study provides a report on marketing strategy adopted by the Coca-Cola Company. Included in the report are the various marketing and/or business issues and opportunities facing Coca-Cola Company, as wel as the characteristics of its current and potential customers. The report also provides a discussion of the various segmentation options available to Coca-Cola Company and then gives a recommendation of the most appropriate market segmentation that the company can focus in order to achieve profitable sales growth. An analysis of the company's strengths and weaknesses based on a proposed marketing mix for a positioning strategy is also given.

  16. The real thing: a profile of the coca cola company

    OpenAIRE

    Hartogh, Matthew

    2007-01-01

    Competition In its core competency, the Coca-Company has only one serious competitor, the PepsiCo Company, maker of Pepsi-Cola. Current market share of the two companies in the United States stands at 43.7% for Coca-Cola against 31.6% for PepsiCo. British firm Cadbury Schweppes comes in third in the American market with its 7UP and Dr. Pepper brands but does not have a head to head cola competitor for Coca-Cola. Supermarket “private label” cola brands are a substitute beverage for the bi...

  17. Coca: High Altitude Remedy of the Ancient Incas.

    Science.gov (United States)

    Biondich, Amy Sue; Joslin, Jeremy D

    2015-12-01

    The use of coca leaf for medicinal purposes is a centuries-old tradition of the native peoples of South America. Coca products are thought by many laypersons to provide risk-free benefits to users participating in strenuous activities at high altitude. Physiologic studies of coca have increased understanding of its possible mechanism of action as well as its potential impact on high altitude activities. This present work explores the role of coca throughout the history of the Andean peoples and explores whether this ancient remedy has a place in modern medicine. A focused summary of research articles with particular relevance to the field of wilderness medicine is also included to better provide the reader with lessons not only from history but also from another culture. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  18. Observaciones en enfermos mentales habituados a la coca

    OpenAIRE

    Gutiérrez Noriega, Carlos

    2016-01-01

    Estudio en seis enfermos mentales habituados a la coca. En sólo un caso encuentra relación entre el cocaísmo y la alteración mental. Lo más frecuente son las alucinaciones, ideas delirantes de persecución y alteraciones cenestésicas. En todos los casos hubo bradicardia e hipotensión arterial. El metabolismo basal disminuye durante la abstinencia.

  19. Corporate Citizenship: Case study of Coca-Cola Beverages Hrvatska

    OpenAIRE

    Tafra-Vlahović, Majda

    2010-01-01

    The aim of this research was to investigate whether the corporate social responsibility (CSR) strategy implemented by Coca-Cola Beverages Croatia during the past four years has had a positive impact on the reputation of this company and on the overall business. The researcher intended to explore attitudes of Coca-Cola Beverages employees about CSR and the mentioned community relations model in order to evaluate whether the CSR policy of the company has had an impact on internal stakehol...

  20. Belgian coca-cola-related outbreak: intoxication, mass sociogenic illness, or both?

    Science.gov (United States)

    Gallay, A; Van Loock, F; Demarest, S; Van der Heyden, J; Jans, B; Van Oyen, H

    2002-01-15

    An epidemic of health complaints occurred in five Belgian schools in June 1999. A qualitative investigation described the scenario. The role of soft drinks was assessed by using a case-control study. Cases were students complaining of headache, dizziness, nausea, vomiting, abdominal pain, diarrhea, or trembling. Controls were students present at school on the day of the outbreak but not taken ill. An analysis was performed separately for school A, where the outbreak started, and was pooled for schools B-E. In school A, the attack rate (13.2%) was higher than in schools B-E (3.6%, relative risk = 3.6, 95% confidence interval (CI): 2.5, 5.3). Exclusive consumption of regular Coca-Cola (school A: odds ratio (OR) = 29.7, 95% CI: 1.32, 663.6; schools B-E: OR = 7.3, 95% CI: 2.9, 18.0) and low mental health score (school A: OR = 16.1, 95% CI: 1.3, 201.9; schools B-E: OR = 3.1, 95% CI: 1.5, 6.6) were independently associated with the illness. In schools B-E, consumption of Fanta, consumption of Coca-Cola light, and female gender were also associated with the illness. It seems reasonable to attribute the first cases of illness in school A to regular Coca-Cola consumption. However, mass sociogenic illness could explain the majority of the other cases.

  1. Efectos cardiovasculares de la cocaína

    Directory of Open Access Journals (Sweden)

    Ubier Gómez

    2001-04-01

    Full Text Available

    La cocaína es un alcaloide derivado de la planta de coca, la cual es nativa de Sur América. Hay datos arqueológicos de esta planta desde 300 años a. C. en los cuales se encontró la primera prueba del uso de coca en humanos. En este tiempo la coca fue reconocida por su habilidad de producir energía, quitar la fatiga y disminuir el hambre.
    La cocaína es la droga ilícita más usada después de la marihuana. La
    frecuencia es mayor en hombres entre los 18-25 años.
    En los años 70 y 80 con el desarrollo del freebase y el crack se revolucionó el uso de esta droga, proporcionando una forma que podría ser fumada.
    Los síntomas que relatan los pacientes que usan cocaína son principalmente en el sistema cardiovascular; otros son neurológicos,
    pulmonares, gastrointestinales, etc.

     

     

  2. Coca: The History and Medical Significance of an Ancient Andean Tradition

    Directory of Open Access Journals (Sweden)

    Amy Sue Biondich

    2016-01-01

    Full Text Available Coca leaf products are an integral part of the lives of the Andean peoples from both a cultural and traditional medicine perspective. Coca is also the whole plant from which cocaine is derived. Coca products are thought to be a panacea for health troubles in regions of South America. This review will examine the toxicology of whole coca and will also look at medicinal applications of this plant, past, present, and future.

  3. Results of long-term carcinogenicity bioassays on Coca-Cola administered to Sprague-Dawley rats.

    Science.gov (United States)

    Belpoggi, Fiorella; Soffritti, Morando; Tibaldi, Eva; Falcioni, Laura; Bua, Luciano; Trabucco, Francesca

    2006-09-01

    Coca-Cola was invented in May 1886 in Atlanta, Georgia by a pharmacist who, by accident or design, mixed carbonated water with the syrup of sugar, phosphoric acid, caffeine, and other natural flavors to create what is known as "the world's favorite soft drink." Coca-Cola is currently sold in more than 200 countries and in early 2000, the company sold its 10 billionth unit case of Coca-Cola branded products. Given the worldwide consumption of Coca-Cola, a project of experimental bioassays to study its long-term effects when administered as substitute for drinking water on male and female Sprague-Dawley rats was planned and executed. The objective of the project was to study whether and how long-term consumption of Coca-Cola affects the basic tumorigram of test animals. The bioassays were performed on rats beginning at different ages, namely: (a) on males and females exposed since embryonic life or from 7 weeks of age; and (b) on males and females exposed from 30, 39, or 55 weeks of age. Overall, the project included 1999 rats. During the biophase, data were collected on fluid and feed consumption, body weight, and survival. Animals were kept under observation until spontaneous death and underwent complete necropsy. The results indicate: (a) an increase in body weight in all treated animals; (b) a statistically significant increase of the incidence in females, both breeders and offspring, bearing malignant mammary tumors; (c) a statistically significant increase in the incidence of exocrine ademonas of the pancreas in both male and female breeders and offspring; and (d) an increased incidence, albeit not statistically significant, of pancreatic islet cell carcinomas in females, a malignant tumor which occurs very rarely in our historical controls. On the basis of the results of this study, excessive consumption of regular soft-drinks should be generally discouraged, in particular for children and adolescents.

  4. Effects of an acidic beverage (Coca-Cola) on absorption of ketoconazole.

    Science.gov (United States)

    Chin, T W; Loeb, M; Fong, I W

    1995-08-01

    Absorption of ketoconazole is impaired in patients with achlorhydria. The purpose of this study was to determine the effectiveness of a palatable acidic beverage (Coca-Cola Classic, pH 2.5) in improving the absorption of ketoconazole in the presence of drug-induced achlorhydria. A prospective, randomized, three-way crossover design with a 1-week wash-out period between each treatment was employed. Nine healthy nonsmoking, nonobese volunteers between 22 and 41 years old were studied. Each subject was randomized to receive three treatments: (A) ketoconazole 200-mg tablet with water (control), (B) omeprazole (60 mg) followed by ketoconazole (200 mg) taken with water, and (C) omeprazole (60 mg) followed by ketoconazole (200 mg) taken with 240 ml of Coca-Cola Classic. The pH values of gastric aspirates were checked after omeprazole was administered to confirm attainment of a pH of > 6. Multiple serum samples were obtained for measurements of ketoconazole concentrations by high-pressure liquid chromatography. The mean area under the ketoconazole concentration-time curve from zero to infinity for the control treatment (17.9 +/- 13.1 mg.h/liter) was significantly greater than that for treatment B (3.5 +/- 5.1 mg.h/liter; 16.6% +/- 15.0% of control). The mean peak concentration was highest for the control treatment (4.1 +/- 1.9 micrograms/ml), for which the mean peak concentration showed a significant increase over that for treatment B. The absorption of ketoconazole was reduced in the presence of omeprazole-induced achlorhydria. However, drug absorption was significantly increased, to approximately 65% of the mean for the control treatment, when the drug was taken with an acidic beverage, such as Coca-Cola.

  5. Aspectos bionômicos de Geometridae (Lepidoptera) Erythroxylum microphyllum (Erythroxylaceae) na região de São Carlos, SP.

    OpenAIRE

    Gláucia Marconato

    2001-01-01

    Este trabalho foi realizado em área de cerrado, próximo a mata ripária. Foram estudados os Geometridae associados a Erythroxylum microphyllum. As coletas foram realizadas quinzenalmente, durante um ano por meio de guarda-chuva entomológico. As larvas foram criadas em laboratório, utilizando a planta hospedeira para alimentá-las. Ocorreram 22 espécies de Geometridae distribuídas em 15 gêneros, 11 gêneros de Hymenoptera Parasitica e dois Diptera Tachinidae. Dentre as espécies de Geometridae,...

  6. The Coca-Cola incident in Belgium, June 1999.

    Science.gov (United States)

    Nemery, B; Fischler, B; Boogaerts, M; Lison, D; Willems, J

    2002-11-01

    The present paper describes the outbreak of health complaints that occurred in Belgium, in June 1999, among schoolchildren and members of the general public in relation to the consumption of Coca-Cola and other soft drinks. The outbreak took place in the wake of a major food crisis, caused by PCB/dioxin contamination of animal feed, that had erupted shortly before. The clinical features (absence of serious poisoning) and epidemiological characteristics of the Coca-Cola outbreak pointed to mass sociogenic illness, and no subsequent toxicological or other data have refuted this hypothesis.

  7. Strategic analysis of the coca-cola company

    OpenAIRE

    Puravankara, Dinesh

    2007-01-01

    This paper performs a strategic analysis of The Coca-Cola Company, a leader in the beverage industry. Coca-Cola, the world’s leading soft drink maker, operates in more than 200 countries and owns or licenses 400 brands of nonalcoholic beverages. The company faces challenges in today’s marketplace because of market driven changes, regulatory changes and socio-economic changes. An external analysis of the soft drink industry is performed to understand the impact of environment. An internal anal...

  8. Miks Coca-Cola enam ei kihise? / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2004-01-01

    Autor teeb USA äriajakirjanduse põhjal ülevaate Coca-Cola Company maine, turupositsiooni ja aktsiakursi langemise põhjustest alates 1997. aastast. Analüütikute sõnul on korporatsioon olnud ebaedukas tippkaadri voolavuse, sisekonfliktide, pidevate ümberkorralduste ja töötajate koondamiste tõttu. Praegune peadirektor Neville Isdelle on püstitanud eesmärgiks firma sisekultuuri parandamise, et keskenduda liidripositsiooni kindlustamisele turul. Diagramm: Karastusjookidel gaas väljas. Vt. samas: Coca-Cola ja Pepsi - üheskoos alla

  9. Hvorfor køber forbrugerne Coca Cola, når de bedst kan lide Pepsi?

    DEFF Research Database (Denmark)

    Jantzen, Christian

    2011-01-01

    Coca Cola kan i modsætning til Pepsi Cola aktivere den præfrontale cortex – derfor er det selvfølgelig Coca, vi vil have!......Coca Cola kan i modsætning til Pepsi Cola aktivere den præfrontale cortex – derfor er det selvfølgelig Coca, vi vil have!...

  10. Two new species of gall midges (Diptera, Cecidomyiidae associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    VC Maia

    Full Text Available Two new species of gall midges (Diptera, Cecidomyiidae Dasineura ovalifoliae and Clinodiplosis maricaensis are described based on material from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil. Both species are associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae. The former is the gall inducer and the latter an inquiline.

  11. Two new species of gall midges (Diptera, Cecidomyiidae) associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae) from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil.

    Science.gov (United States)

    Maia, V C; Fernandes, S P C

    2011-05-01

    Two new species of gall midges (Diptera, Cecidomyiidae) Dasineura ovalifoliae and Clinodiplosis maricaensis are described based on material from the Barra de Maricá restinga, Maricá, Rio de Janeiro, Brazil. Both species are associated with Erythroxylum ovalifolium Peyr. (Erythroxylaceae). The former is the gall inducer and the latter an inquiline.

  12. The spermicidal potency of Coca-Cola and Pepsi-Cola.

    Science.gov (United States)

    Hong, C Y; Shieh, C C; Wu, P; Chiang, B N

    1987-09-01

    The inhibitory effect of Old Coke, caffeine-free New Coke, New Coke, Diet Coke and Pepsi-Cola on human sperm motility was studied with a trans-membrane migration method. None of them could decrease sperm motility to less than 70% of control within one hour. A previous study which claimed a marked variation of spermicidal potencies among different formulations of Coca-Cola could not be confirmed. Even if cola has a spermicidal effect, its potency is relatively weak as compared with other well-known spermicidal agents.

  13. Coca leaf chewing as therapy for cocaine maintenance.

    Science.gov (United States)

    Hurtado-Gumucio, J

    2000-10-01

    Major ethnic groups in Bolivia (Aymaras and Quechuas) have chewed the coca leaf for generations upon generations without health problems. The effects of coca leaf chewing produce a level of social and economic adaptation that is beyond what is normally possible. This was a major factor during the Spanish colonization of Bolivia, when forced native labor was used extensively. The cocaine base, or "pasta", may be seen as a type of South American crack. Its obligatory method of administration is smoking. A primary condition of the "pasta" smoker is compulsive drug-search behavior and addiction to cocaine base destroys emotional and mental balance. Socio-economic maladjustment is the norm amongst "pasta" addicts. Since 1984 I have recommended the chewing of the coca leaf, between 100 to 200 grams of coca leaf per week for the treatment of cocaine dependence. Since this treatment was dispensed on an ad hoc basis, it was not possible to measure the relapses. However, an assessment was conducted on the basis of mental condition and level of social and economic adaptation before and after treatment. The patent's level of social acceptance, before treatment, only reached 60% at most, and after treatment, 26% improved their level of adaptation. Four patients among 50 reached an adaptation level of 100%. Upon final assessment, the level of social adaptation prior to treatment was only 28%, after treatment as many as 48.8% of the patients were socially adapted.

  14. NATO palkas Coca-Colast mainekujundaja / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2008-01-01

    NATO otsustas oma kaubamärgi värskendamiseks palgata viimased kaks aastat Coca-Cola mainet kujundanud Michael Stopfordi, kelle põhiülesandeks tõenäoliselt jääb tavakodanikele organisatsiooni tähtsuse ja rolli selgitamine

  15. Comunicación emocional: Coca-Cola

    OpenAIRE

    García Hernández, María

    2015-01-01

    Partiendo de la inteligencia emocional, de donde nace la comunicación emocional, llegamos a la influencia de esta en la publicidad, presente en una buena parte de las campañas publicitarias actuales. La autora se centra en el caso de Coca-Cola y sus campañas publicitarias

  16. Effect of an acidic beverage (Coca-Cola) on the pharmacokinetics of carbamazepine in healthy volunteers.

    Science.gov (United States)

    Malhotra, S; Dixit, R K; Garg, S K

    2002-01-01

    The effect of an acidic beverage (Coca-Cola) on the pharmacokinetics of a single dose of carbamazepine was studied. In a two-way cross-over design with a 1 week washout period, 10 healthy volunteers were randomized to received 200 mg carbamazepine orally with 300 ml of Coca-Cola or water. Blood samples were collected at 0, 0.5, 1, 2, 3, 6, 9, 12, 24, 48 and 72 h after drug administration. Plasma carbamazepine levels were higher with Coca-Cola as compared to water. The AUC0-infinity and Cmax of carbamazepine were significantly enhanced after Coca-Cola while tmax was achieved earlier with Coca-Cola. The results of the study indicate that concomitant administration of Coca-Cola enhances the rate and extent of absorption of carbamazepine.

  17. CHINA DREAM or CHINESE DREAM based on COCA

    Institute of Scientific and Technical Information of China (English)

    LIU Meng-qing

    2016-01-01

    There has a lot of discussion about the correct expression of CHINESE DREAM or CHINA DREAM. This paper aims to make well use of COCA, a free online corpus, to clear this question. After contrast, we finally find that the exact expression is CHINESE DREAM instead of the original CHINA DREAM. The application of corpus can also be a new pattern for us to pur-sue our study career and will also be an effective way to help us in research field.

  18. Supply Chain Maturity Assessment of Coca Cola Ghana Ltd

    OpenAIRE

    Tetteh, Quaye

    2015-01-01

    This study aims to assess the supply chain process management of Coca Cola Ghana Ltd; this research is of importance due to its potential to point out processes that can yield higher performance of the supply chain and those processes that can be enhanced for higher per-formance levels. The sample for this study was selected using purposive sampling; five supply chain man-agement practitioners in the company were used for the data extraction. Questionnaires were sent to these five respond...

  19. Promotion demand forecast: A Case Study of Coca Cola Enterprise

    OpenAIRE

    Lai, Hoi-Yin Cecilia

    2007-01-01

    In this highly competitive business environment, forecasting becomes one of the hot topics. Every business organization uses forecasts for decision marking. Forecasting can help companies to determine the market strategy. It also helps in production planning and resources allocation. A good forecast can help the management team to make the best decision. Nowadays, it is important to develop a collaborative partnership within the supply chain. Coca Cola Enterprise (CCE) is working with its cus...

  20. The effect of Coca-Cola and fruit juices on the surface hardness of glass-ionomers and 'compomers'.

    Science.gov (United States)

    Aliping-McKenzie, M; Linden, R W A; Nicholson, J W

    2004-11-01

    The interaction of tooth-coloured dental restorative materials (a conventional glass-ionomer, two resin-modified glass-ionomers and two compomers) with acidic beverages has been studied with the aim of investigating how long-term contact affects solution pH and specimen surface hardness. For each material (ChemFil Superior, ChemFlex, Vitremer Core Build-Up/Restorative, Fuji II LC, Dyract AP and F2000) disc-shaped specimens were prepared and stored in sets of six in the following storage media: 0.9% NaCl (control), Coca-Cola, apple juice and orange juice. After time intervals of 1 day, 1 week, 1 month, 3 months, 4 months, 6 months and 1 year, solution pH and Vickers Hardness Number were determined for each individual specimen. Differences were analysed by anova followed by Student-Newman-Keuls post hoc analysis. All materials were found to reduce the pH of the 0.9% NaCl, but to increase the pH of the acidic beverages. The conventional glass-ionomers dissolved completely in apple juice and orange juice, but survived in Coca-Cola, albeit with a significantly reduced hardness after 1 year. The other materials survived in apple juice and orange juice, but showed greater reductions in surface hardness in these beverages than in Coca-Cola. Fruit juices were thus shown to pose a greater erosive threat to tooth coloured materials than Coca-Cola, a finding which is similar to those concerning dentine and enamel towards these drinks.

  1. Evaluation of the Coca-Cola company travel health kit.

    Science.gov (United States)

    Harper, Lynne A; Bettinger, Julie; Dismukes, Roberta; Kozarsky, Phyllis E

    2002-01-01

    The Coca-Cola travel health kit has been used for about one decade for international travelers and required evaluation to see if the items contained were appropriate for the employees. Two hundred thirty-four travelers were sampled and filled out a voluntary survey including questions about demographic information, travel history, and usage and value of the contents of the travel health kit. One hundred eighty-one surveys were returned; 65% of the respondents were male, and the majority of travelers were between the ages of 36 and 45 years. The most useful items were analgesics and medications used for gastrointestinal problems. In general, the items identified as being the least useful were those requiring specialized use by a medical practitioner, such as needles and syringes. Suggestions of items to be added to the kit included vitamins, cough drops, sleep aids, and eye drops. A surprising result that Coca-Cola employees expressed the desire for brand name rather than generic items. Evaluation of the Coca-Cola Company travel health kit revealed it to be very useful to most corporate travelers. Suggestions that were made will be taken into consideration in designing a new kit, and consideration is being given to whether a basic travel health kit should be provided to which travelers can add other items depending on their personal needs.

  2. Modificaciones psicológicas y fisiológicas producidas por la coca y la cocaína en los coqueros

    Directory of Open Access Journals (Sweden)

    Vicente Zapata Ortiz

    1944-06-01

    Full Text Available Se ha estudiado el efecto de la cocaína y de la coca en sujetos no habituados y habituados a la coca. Los resultados son los siguientes: 1. En los sujetos no habituados la cocaína produce un moderado retardo del tiempo de reacción sensorial para estímulos auditivos, a las dosis de 0.5, 1 y 1.5 mgrs. por kilo de peso corporal. 2. En los sujetos no habituados a la cocaína disminuye el tiempo de ejecución del test de Valdizán para el estudio de la atención (en el 88 % de los casos, pero aumenta el número de errores en más del 50 % de los Casos estudiados. 3. Sobre los sujetos habituados o coqueros la coca y la cocaína (de 4 a 6 mlgr. por kg. de peso retardan el tiempo de reacción sensorial para estímulos auditivos. 4. En el 91 % de los coqueros estudiados la coca disminuye el tiempo de ejecución del test de Valdizán y en el 63% disminuyen los errores. 5. Sobre los sujetos habituados, la coca durante el coqueo produce elevación de temperatura (que puede llegar a estados subfebriles, aumento del pulso, presión arterial y reflejos tendinosos; leve aumento de la respiración; modificaciones del reflejo óculo-cardiaco de carácter parasimpaticotónico en la mayoría, y de carácter simpaticotónico en muy pocos casos.

  3. Coca-Cola ja Pepsi - vennad, nii et veri lendab / Argo Luude, Ave Peetri ; interv. Urmas Vahe

    Index Scriptorium Estoniae

    Luude, Argo

    2006-01-01

    Endine PepsiCo Eesti divisjoni juht ning Suurbritannia Coca-Cola suurte kaubanduskettide turundusjuht ettevõtete vahelisest konkurentsist. Vt. samas: Mida on vaja teada Coca-Colast?; Mida on tarvis teada Pepsi-Colast?

  4. Forests and drugs: coca-driven deforestation in tropical biodiversity hotspots.

    Science.gov (United States)

    Dávalos, Liliana M; Bejarano, Adriana C; Hall, Mark A; Correa, H Leonardo; Corthals, Angelique; Espejo, Oscar J

    2011-02-15

    Identifying drivers of deforestation in tropical biodiversity hotspots is critical to assess threats to particular ecosystems and species and proactively plan for conservation. We analyzed land cover change between 2002 and 2007 in the northern Andes, Chocó, and Amazon forests of Colombia, the largest producer of coca leaf for the global cocaine market, to quantify the impact of this illicit crop on forest dynamics, evaluate the effectiveness of protected areas in this context, and determine the effects of eradication on deforestation. Landscape-level analyses of forest conversion revealed that proximity to new coca plots and a greater proportion of an area planted with coca increased the probability of forest loss in southern Colombia, even after accounting for other covariates and spatial autocorrelation. We also showed that protected areas successfully reduced forest conversion in coca-growing regions. Neither eradication nor coca cultivation predicted deforestation rates across municipalities. Instead, the presence of new coca cultivation was an indicator of municipalities, where increasing population led to higher deforestation rates. We hypothesize that poor rural development underlies the relationship between population density and deforestation in coca-growing areas. Conservation in Colombia's vast forest frontier, which overlaps with its coca frontier, requires a mix of protected areas and strategic rural development to succeed.

  5. 75 FR 61141 - In the Matter of The Coca-Cola Company; Analysis of Agreement Containing Consent Order to Aid...

    Science.gov (United States)

    2010-10-04

    ... FEDERAL TRADE COMMISSION [File No. 101 0107] In the Matter of The Coca-Cola Company; Analysis of... should be submitted by using the following weblink: ( https://ftcpublic.commentworks.com/ftc/coca-cola....com/ftc/coca-cola ). If this Notice appears at ( http://www.regulations.gov/search/index.jsp ), you...

  6. Coca-Cola : kasumi languses on süüdi Põhja-Euroopa kehv ilm / Raivo Sormunen

    Index Scriptorium Estoniae

    Sormunen, Raivo, 1976-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 29. sept. lk. 6. Karastusjookide tootja Coca-Cola andis kasumihoiatuse. Ettevõtte majandustulemuste languse põhjustest. Diagramm: Coca-Cola aktsia aasta madalaimal tasemel. Vt. samas: Annika Matson. Coca-Cola jooksev kvartal Eestis saladus

  7. Coca and poppy eradication in Colombia: environmental and human health assessment of aerially applied glyphosate.

    Science.gov (United States)

    Solomon, Keith R; Anadón, Arturo; Carrasquilla, Gabriel; Cerdeira, Antonio L; Marshall, Jon; Sanin, Luz-Helena

    2007-01-01

    The production of coca and poppy as well as the processing and production of cocaine and heroin involve significant environmental impacts. Both coca and poppy are grown intensively in a process that involves the clearing of land in remote areas, the planting of the crop, and protection against pests such as weeds, insects, and pathogens. The aerial spray program to control coca and poppy production in Colombia with the herbicide glyphosate is conducted with modern state-of-the-art aircraft and spray equipment. As a result of the use of best available spray and navigation technology, the likelihood of accidental off-target spraying is small and is estimated to be less than 1% of the total area sprayed. Estimated exposures in humans resulting from direct overspray, contact with treated foliage after reentry to fields, inhalation, diet, and drinking water were small and infrequent. Analyses of surface waters in five watersheds showed that, on most occasions, glyphosate was not present at measurable concentrations; only two samples had residues just above the method detection limit of 25 microg/L. Concentrations of glyphosate in air were predicted to be very small because of negligible volatility. Glyphosate in soils that are directly sprayed will be tightly bound and biologically unavailable and have no residual activity. Concentrations of glyphosate plus Cosmo-Flux will be relatively large in shallow surface waters that are directly oversprayed (maximum instantaneous concentration of 1,229microgAE/L in water 30cm deep); however, no information was available on the number of fields in close proximity to surface waters, and thus it was not possible to estimate the likelihood of such contamination. The formulation used in Colombia, a mixture of glyphosate and Cosmo-Flux, has low toxicity to mammals by all routes of exposure, although some temporary eye irritation may occur. Published epidemiological studies have not suggested a strong or consistent linkage between

  8. Performance Analysis Comparison Of Coca Cola And Pepsi

    OpenAIRE

    The, Glenny Marselia; Saerang, David Paul Elia; Tumewu, Ferdinand

    2014-01-01

    All companies fight to get as many consumers as they can and it makes, product, price, place and promotion become important factors to make a company has a successful marketing campaign. The companies spend much money for create an attractive product at an affordable price, a place that can be reached, and the promotion that can be well-received by the public. So, regarding that fact, the researcher writes a study about the performance analysis comparison of Coca Cola and Pepsi in Manado b...

  9. An Energy Dispersive X-ray Spectroscopy Analysis of Elemental Changes of a Persimmon Phytobezoar Dissolved in Coca-Cola.

    Science.gov (United States)

    Iwamuro, Masaya; Urata, Haruo; Higashi, Reiji; Nakagawa, Masahiro; Ishikawa, Shin; Shiraha, Hidenori; Okada, Hiroyuki

    To investigate the mechanism of phytobezoar dissolution by Coca-Cola(®), persimmon phytobezoar pieces removed from a 60-year-old Japanese woman were analyzed by energy dispersive X-ray spectroscopy. The amount of calcium significantly decreased after dissolution treatment using Coca-Cola(®), suggesting a potential contribution of calcium to dissolution mechanisms. Moreover, immersion in Coca-Cola(®) for 120 hours on the exterior surface revealed that Coca-Cola(®) did not permeate persimmon phytobezoars. This is the first study to investigate the mechanisms of persimmon phytobezoar permeability and dissolution induced by Coca-Cola(®).

  10. Brief communication: effect of coca-leaf chewing on salivary progesterone assays.

    Science.gov (United States)

    Vitzthum, V J; von Dornum, M; Ellison, P T

    1993-12-01

    Although there is evidence for reduced fertility in Andean and Himalayan populations at higher altitudes, factors other than hypoxia may be primarily responsible. A valuable approach in the investigation of these fertility determinants is the use of salivary steroid assays. However, coca-leaf chewing--a ubiquitous practice among high altitude Andean populations--has negative consequences for the accurate measurement of ovarian steroids. This report evaluates the effects of coca-leaf chewing on assays of salivary progesterone. Study participants include naive and habitual users of coca leaf from La Paz and El Alto, Bolivia. Approximately 300 saliva samples were collected immediately before, during, and after coca-leaf chewing. The series includes samples with and without the alkaloid enhancer typically used by coca-leaf chewers. Coca chewing produces false salivary progesterone values that mimic luteal phase values. On the basis of this study, an appropriate protocol is developed for the collection of salivary samples in coca-leaf chewing populations. These results verify the feasibility of salivary assays, even for very difficult field conditions, and highlight the necessity of establishing suitable collection procedures before full field implementation of saliva sampling.

  11. 21 CFR 182.20 - Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).

    Science.gov (United States)

    2010-04-01

    ... (clary sage) Salvia sclarea L. Clover Trifolium spp. Coca (decocainized) Erythroxylum coca Lam. and other spp. of Erythroxylum. Coffee Coffea spp. Cola nut Cola acuminata Schott and Endl., and other spp. of Cola. Coriander Coriandrum sativum L. Cumin (cummin) Cuminum cyminum L. Curacao orange peel (orange...

  12. 21 CFR 582.20 - Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).

    Science.gov (United States)

    2010-04-01

    .... Clover Trifolium spp. Coca (decocainized) Erythroxylum coca Lam. and other spp. of Erythroxylum. Coffee Coffea spp. Cola nut Cola acuminata Schott and Endl., and other spp. of Cola. Coriander Coriandrum... Cola acuminata Schott and Endl., and other spp. of Cola. Laurel berries Laurus nobilis L. Laurel leaves...

  13. Drugs and Protected Areas: Coca Cultivation and Social Acceptance of Bahuaja-Sonene National Park in Peru

    Directory of Open Access Journals (Sweden)

    Jaqueline Garcia-Yi

    2015-06-01

    Full Text Available Cocaine is extracted from coca: a native bush from the Amazon rainforest. Coca is mostly grown in remote areas to avoid government intervention, and it has been increasingly cultivated inside protected areas (PAs. The effects of coca cultivation on the preservation of PAs are largely unknown. This research uses panel data (2006–2008 from a total of 684 farmers to evaluate the influence of coca growing on the acceptance of PAs, using as case study a farmer community located within the buffer zone of Bahuaja-Sonene National Park (Peru. All farmers are coffee growers and some complement their income with coca production. The area has not been subject of forced coca eradication activities. The data were analyzed using probit models with covariance matrix correction for cluster errors by year, with and without interaction effects. The results suggest that coca growers are more likely to state a positive opinion about the PA than non-coca growers. This may reflect the fact that non-coca growers need extensive areas of land for coffee cultivation in order to approach the economic benefits obtained by farmers who also grow coca. However the likelihood of stating a positive opinion by coca growers decreases the higher the perception that coca cultivation has increased in the region. Coca growers may be afraid that large coca areas would lead to the implementation of forced eradication activities. In such a case, the BSNP would restrict the access to remote land resources, which in turn decreases the support for this PA.

  14. [Two cases of phytobezoars treated by adminsitration of Coca-Cola by oral route].

    Science.gov (United States)

    Lee, Hyun Jai; Kang, Hyoun Goo; Park, Se Young; Yi, Chea Yong; Na, Gyoung Jun; Lee, Tae Yeong; Kim, Sang Hyun; Song, Chul Soo

    2006-12-01

    Bezoars are concretions of foreign bodies found in the gastrointestinal tract. In the past, most common method for the treatment of bezoar was surgical management. However, the current treatment methods include chemical dissolution and endoscopic mechanical lithotripsy. There were few reports on the treatment of phytobezoars by nasogastric Cola lavage. However, there was no report succeeded by oral route alone. In our two cases, phytobezoars were treated by oral administration of Coca-Cola. Our patients drank 700-800 mL of Coca-Cola daily, and after two months, complete dissolutions of bezoars were achieved. We report two cases of phytobezoars completely treated by drinking Coca-Cola.

  15. Drink! : En analys av The Coca-Cola Company's marknadsföringshistoria ur ett moderniseringsperspektiv

    OpenAIRE

    Hedblom, Karin; Forsgren, Oskar

    2009-01-01

    Drink! The Marketing History of The Coca-Cola Company: A Modernization Perspective examines the development of The Coca-Cola Company’s marketing history, from the founding of the company in 1886 until today. The Coca-Cola Company has been superior on the market for over a century. It has also developed along with the urbanisation of its society, which is interesting in a modernization perspective. The essay investigates the marketing strategies of the company, with focus on three themes: gend...

  16. Presencia de plaguicidas en muestras de cocaína

    OpenAIRE

    García Fernández, J. C.; Villaamil, Edda C.; Ravenna, Alicia; Roses, Otmaro Enrique

    1989-01-01

    Se estudió por cromatografía gaseosa la presencia de residuos de plaguicidas en 51 muestras de cocaína provenientes de incautaciones realizadas en el norte argentino, identificándose en 36 muestras 13 plaguicidas distintos, mientras que en 15 muestras no se halló ninguno. Los plaguicidas revelados en mayor cantidad de muestras fueron γ-HCH (0,01 a 0,20 ppm; n = 26), Heptacloro (0,02 a 0,10 ppm; n = 15) y pp'DDE (0,04 a 1,9 ppm; n = 15), mientras en menor número se encontró Fenitrotión, α-HCL,...

  17. Coca-colonization and hybridization of diets among the Tz'utujil Maya.

    Science.gov (United States)

    Nagata, Jason M; Barg, Frances K; Valeggia, Claudia R; Bream, Kent D W

    2011-01-01

    Biomedical health professionals express increasing concern that rising consumption of soft drinks and processed foods in Mayan and Latin American eating patterns may lead to detrimental nutritional and health consequences. Scholars debate whether the pervading presence of Coca-Cola and Pepsi in developing countries represents "Coca-Colonization," synonymous with cultural imperialism, or cultural hybridization. Using mixed qualitative and quantitative research methods, including participant observation and semi-structured interviews, this study explores the development of Coca-Colonization and cultural hybridization among the Tz'utujil Maya of Santiago Atitlán, Guatemala. By specifically examining biomedical perspectives, cycles of conquest, the political economy, religion, celebrations, and the physical environment through the lens of soft drinks, this study finds that Coca-Colonization and cultural hybridization are complementary rather than mutually exclusive processes that contribute to dietary transitions, economic development, and differential health beliefs related to soft drink consumption.

  18. An Analysis of Yip's Global Strategy Model, Using Coca-Cola ...

    African Journals Online (AJOL)

    Analysis of the selected business cases suggest a weak fit between the Yip model of a truly Global strategy ... like Coca-Cola in the beverage industry for effective implementation of a global strategy. ... Keywords: Global Strategy, Leadership.

  19. Pengaruh Implementasi CSR Yang Dilakukan Oleh PT. Coca-cola Bottling Indonesia Terhadap Pengembangan Masyarakat Medan

    OpenAIRE

    Lubis, Zulfizar Syahputra

    2013-01-01

    Formulation of the problem in this research is: Is CSR Implementation conducted by PT. Coca-Cola Bottling Indonesia Significant Impact on Community Development. The purpose of this research is to study and analyze how CSR Implementation conducted by PT. Coca-Cola Bottling Indonesia Significant Impact on Community Development. This study is associative, ie research that connects two or more variables to see the effect of these variables. The data used in this study is primary data and secon...

  20. Acute intestinal obstruction caused by a persimmon phytobezoar after dissolution therapy with Coca-Cola.

    Science.gov (United States)

    Ha, Seung Soo; Lee, Hyun Suk; Jung, Min Kyu; Jeon, Seong Woo; Cho, Chang Min; Kim, Sung Kook; Choi, Yong Hwan

    2007-12-01

    Bezoars are concretions or hard masses of foreign matter that are found in the gastrointestinal tract. Recent reports have demonstrated the efficacy of Coca-Cola administration for the dissolution of phytobezors. Here we report on a 73-year-old man with a very large gastric persimmon diospyrobezoar, and this caused small intestinal obstruction after partial dissolution with oral and injected Coca-Cola.

  1. Selling Local Modernization through the Global Corporation: Coca-Cola Bottling in Colombia, 1927-1944

    OpenAIRE

    Ciafone, Amanda

    2018-01-01

    Abstract The Coca-Cola Company sold drink concentrates and licensed rights to its trade-marked brands to contracted bottlers who produced and sold bottled drinks in designated geographic areas around the world, including Colombia, beginning in 1927. The franchise system enabled international expansion without large corporate growth or direct local employment allowing the company to externalize liability and financial risk. The franchise system helped the company situate the production of Coca...

  2. Selling Local Modernization through the Global Corporation: Coca-Cola Bottling in Colombia, 1927-1944

    OpenAIRE

    Amanda Ciafone

    2018-01-01

    The Coca-Cola Company sold drink concentrates and licensed rights to its trademarked brands to contracted bottlers who produced and sold bottled drinks in designated geographic areas around the world, including Colombia, beginning in 1927. The franchise system enabled international expansion without large corporate growth or direct local employment allowing the company to externalize liability and financial risk. The franchise system helped the company situate the production of Coca-Cola with...

  3. Pepsi and Coca Cola in Delhi, India: availability, price and sales.

    OpenAIRE

    Taylor, FC; Satija, A; Khurana, S; Singh, G; Ebrahim, S

    2010-01-01

    : India is experiencing increased consumption of sugar-sweetened carbonated drinks, consumption that may be associated with increased risk of type 2 diabetes and obesity. The aim of the study was to determine the availability, price and quantity sold of 'Pepsi' and 'Coca Cola' in their 'regular' and 'diet' forms in Delhi and London. : A questionnaire about the availability, price and quantity sold per day of both regular and diet Pepsi and Coca Cola was devised and piloted. Using this, a surv...

  4. Influence of an acidic beverage (Coca-Cola) on the pharmacokinetics of phenytoin in healthy rabbits.

    Science.gov (United States)

    Kondal, A; Garg, S K

    2003-12-01

    This study was carried out to evaluate the influence of an acidic beverage (Coca-Cola) on the pharmacokinetics of phenytoin in rabbits. In a cross-over study, phenytoin was given orally at a dose of 30 mg/kg and blood samples were taken at different intervals from 0-24 h. After a washout period of 7 days, Coca-Cola (5 ml/kg) was administered in combination with phenytoin (30 mg/kg) and blood samples were taken at various time intervals from 0-24 h. The same rabbits continued to receive Coca-Cola (5 ml/kg) for another 7 days. On the 8th day, Coca-Cola (5 ml/kg) in combination with phenytoin (30 mg/kg) was administered and blood samples were taken at similar intervals. Plasma was separated and assayed for phenytoin by high performance liquid chromatography (HPLC) and various pharmacokinetic parameters were calculated. It was concluded that an acidic beverage (Coca-Cola) increases the extent of absorption of phenytoin by significantly increasing the Cmax and AUC(o-á) of phenytoin. These results warrant the reduction of phenytoin dose when administered in combination with Coca-Cola to avoid any toxicity. (c) 2003 Prous Science

  5. Colonic obstruction secondary to sigmoid fecaloma endoscopically resolved with Coca-Cola®.

    Science.gov (United States)

    Ontanilla Clavijo, Guillermo; León Montañés, Rafael; Sánchez Torrijos, Yolanda; López Ruiz, Teófilo; Bozada García, Juan Manuel

    2017-04-01

    Colonic obstruction is a relatively common condition in emergency care, with a mortality rate of up to 20%. In 90% of cases it results from colonic or rectal adenocarcinoma, volvulus, or stenosis secondary to diverticular disease. When fecal impaction is the underlying cause, the condition is usually managed conservatively, but may on occasion become complicated and even require surgical intervention. Based on the proven efficacy of Coca-Cola® to dissolve gastric phytobezoars, we report a case of colonic obstruction secondary to sigmoid fecaloma. A 58 years old woman arrived at the Emergency Room (ER) with persistent constipation for the last six days. An abdominal CT scan showed a large fecal mass at the sigmoid colon with retrograde dilated colonic loops. Cleansing enemas and oral lactulose were administered, which failed to resolve the clinical presentation, so we then proceeded to inject Coca-Cola® within the fecaloma using a sclerosing needle, and then washed the fecaloma surface also with Coca-Cola®. After a few minutes we started to fragment the fecalith, the consistency of which had been notably decreased. The use of Coca-Cola® for gastric washes in the management of phytobezoars is well established. Since fecaliths are partly composed of these same substances than phytobezoars, the use of Coca-Cola® might well be warranted against them as in our patient, without surgery. Our case report is the second one published in the literature, in which Coca-Cola® helped solve colonic obstruction secondary to fecaloma.

  6. Influence of acidic beverage (Coca-Cola) on pharmacokinetics of ibuprofen in healthy rabbits.

    Science.gov (United States)

    Kondal, Amit; Garg, S K

    2003-11-01

    The study was aimed at determining the effect of Coca-Cola on the pharmacokinetics of ibuprofen in rabbits. In a cross-over study, ibuprofen was given orally in a dose of 56 mg/kg, prepared as 0.5% suspension in carboxymethyl cellulose (CMC) and blood samples (1 ml) were drawn at different time intervals from 0-12 hr. After a washout period of 7 days, Coca-Cola in a dose of (5 ml/kg) was administered along with ibuprofen (56 mg/kg) and blood samples were drawn from 0-12 hr. To these rabbits, 5 ml/kg Coca-Cola was administered once daily for another 7 days. On 8th day, Coca-Cola (5 ml/kg) along with ibuprofen (56 mg/kg), prepared as a suspension was administered and blood samples (1 ml each) were drawn at similar time intervals. Plasma was separated and assayed for ibuprofen by HPLC technique and various pharmacokinetic parameters were calculated. The Cmax and AUC0-alpha of ibuprofen were significantly increased after single and multiple doses of Coca-Cola, thereby indicating increased extent of absorption of ibuprofen. The results warrant the reduction of ibuprofen daily dosage, frequency when administered with Coca-Cola.

  7. Selling Local Modernization through the Global Corporation: Coca-Cola Bottling in Colombia, 1927-1944

    Directory of Open Access Journals (Sweden)

    Amanda Ciafone

    2018-01-01

    Full Text Available The Coca-Cola Company sold drink concentrates and licensed rights to its trademarked brands to contracted bottlers who produced and sold bottled drinks in designated geographic areas around the world, including Colombia, beginning in 1927. The franchise system enabled international expansion without large corporate growth or direct local employment allowing the company to externalize liability and financial risk. The franchise system helped the company situate the production of Coca-Cola within local economies, conscripting local elites and workers into its industry, and negotiating its representational forms to fit local contexts. The Coca-Cola Company thus benefited from the economic and political power of both the U.S. and the Colombian elite as it established its business in the country beginning in 1927. Examining print advertising from the 1920s and 1940s, the papers of Coca-Cola executives, and publications of the U.S. multinational and its Colombian franchise bottler, this article argues that The Coca-Cola Company tenuously constructed its industry, products, and brands as simultaneously global and local. While localizing the Coca-Cola industry, products, and brand, the company alluded to its modernity and global popularity, available for purchase by enterprising merchants and thirsty consumers in Colombia.

  8. Intoxicação espontânea e experimental por folhas e frutos de erythroxylum deciduum (cocão) em ovinos no Estado de Santa Catarina

    OpenAIRE

    Borelli, Vanessa

    2009-01-01

    Descreve-se uma enfermidade em ovinos de ocorrência sazonal, caracterizada por manifestações nervosas e morte rápida, nos municípios de Rancho Queimado e Ponte Alta do Sul, no estado de Santa Catarina. Alguns produtores relacionavam a doença ao consumo de frutos de uma árvore conhecida como cocão (Erythroxylum deciduum), cuja toxidez já foi descrita anteriormente. Em virtude da ausência de frutos maduros desta árvore por ocasião da ocorrência dos surtos no município de Rancho...

  9. Studi Pendapat Konsumen Terhadap Brand Awareness Brand Equity Dan Brand Image Minuman Coca-cola Di Kota Makassar

    OpenAIRE

    Rezkiawaty, Sitti Utami

    2011-01-01

    The aims of the research are to find out (1) the implementation of the strategy of PT Coca-Cola bottling Indonesia southern Sulawesi in creating brand awareness, brand equity and brand image of coca-cola beverages in the city of Makassar, (2) the consumer opinion about coca-cola beverage product in the city of Makassar, (3) the factors that influence consumer ratings of brand awareness, brand equity, brand image coca-cola beverage products. The research was a descriptive quantitative study co...

  10. Regional Monopoly and Interregional and Intraregional Competition: The Parallel Trade in Coca-Cola between Shanghai and Hangzhou in China

    OpenAIRE

    Yeung, Godfrey; Mok, Vincent

    2006-01-01

    This article uses a “principal-agent-subagent” analytical framework and data that were collected from field surveys in China to (1) investigate the nature and causes of the parallel trade in Coca-Cola between Shanghai and Hangzhou and (2) assess the geographic and theoretical implications for the regional monopolies that have been artificially created by Coca-Cola in China. The parallel trade in Coca-Cola is sustained by its intraregional rivalry with Pepsi-Cola in Shanghai, where Coca-Cola (...

  11. 75 FR 1812 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-01-13

    ... of controlled substances listed in schedule II: Drug Schedule Phenylacetone (8501) II Coca Leaves... registration or re-registration to import crude opium, poppy straw, concentrate of poppy straw or coca leaves... such basic classes of controlled substances listed in schedule I or II, which fall under the authority...

  12. 76 FR 5827 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-02-02

    ... basic classes of controlled substances: Drug Schedule Phenylacetone (8501) II Coca Leaves (9040) II... re-registration to import crude opium, poppy straw, concentrate of poppy straw or coca leaves. As... classes of controlled substances listed in schedule I or II, which fall under the authority of section...

  13. Anestesia no paciente usuário de cocaína Anestesia en el paciente usuario de cocaína Anesthesia in cocaine users

    Directory of Open Access Journals (Sweden)

    Ana Luft

    2007-06-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A cocaína é a droga ilícita mais freqüentemente associada a óbitos, e suas implicações perioperatórias nos pacientes agudamente intoxicados ou com história de uso crônico precisam ser bem conhecidas pelos anestesiologistas. O conhecimento da neurofisiologia, da farmacologia e das conseqüências fisiopatológicas decorrentes do uso da cocaína poderá facilitar o cuidado desses pacientes. O objetivo deste trabalho foi revisar as informações sobre a cocaína e suas interações com a anestesia. CONTEÚDO: O artigo discute a farmacologia da cocaína, as conseqüências fisiopatológicas decorrentes do seu uso e as interações com a anestesia. CONCLUSÕES: A compreensão e o reconhecimento precoce das complicações associadas ao uso de cocaína são essenciais para o manuseio adequado de pacientes usuários desta droga. O anestesiologista deve estar preparado, pois tanto as anestesias regionais quanto a geral apresentam riscos significativos nesses pacientes.JUSTIFICATIVA Y OBJETIVOS: La cocaína es la droga ilícita más frecuentemente asociada a decesos, y sus implicaciones perioperatorias en los pacientes agudamente intoxicados o con historial de uso crónico necesitan ser muy bien conocidas por los anestesiólogos. El conocimiento de la neurofisiología, de la farmacología y de las consecuencias fisiopatológicas provenientes del uso de la cocaína podrá facilitar el cuidado de esos pacientes. El objetivo de este trabajo fue revisar las informaciones sobre la cocaína y sus interacciones con la anestesia. CONTENIDO: El artículo discute la farmacología de la cocaína, las consecuencias fisiopatológicas provenientes de su uso y las interacciones con la anestesia. CONCLUSIONES: La comprensión y el reconocimiento precoz de las complicaciones asociadas al uso de la cocaína son esenciales para el manejo adecuado de pacientes usuarios de esa droga. El anestesiólogo debe estar preparado, pues tanto las

  14. Efectos de la cocaína sobre los niveles de y-aminobutirato, glutamato y aspartato en el núcleo accumbens e hipocampo de rata

    Directory of Open Access Journals (Sweden)

    Rafael A. Ulloque

    2001-09-01

    Full Text Available Se estudiaron los efectos agudos y crónicos de la cocaína sobre los niveles de y-aminobutirato (GABA, glutamato y aspartato en el núcleo accumbens e hipocampo de ratas, para lo cual se administró cocaína en forma aguda y crónica (intraperitoneal a grupos de ratas. El primer grupo recibió 30 mglkg; la administración crónica se inició con 30 mg/kg y se incrementaron 5 mg/kg cada cuatro dias durante 20 días. Los grupos controles recibieron el respectivo volumen de solución salina, por la misma vía y por el tiempo respectivo. A los 30 minutos de administrada la cocaína en forma aguda y 24 horas después de la última dosis crónica, los animales fueron decapitados, los cerebros separados rápidamente del cráneo y colocados en solución salina normal a O OC durante 10 minutos. Posteriormente, se tomaron muestras del núcleo accumbens y del hipocampo. Se procedió igual con los grupos controles. Los niveles de GABA, glutamato y aspartato se determinaron utilizando técnicas enzimáticas y medidas espectrofotométricas. Los resultados muestran que la administración aguda o crónica de cocaína incrementa significativamente el glutamato y el aspartato tanto en el núcleo accumbens como en el hipocampo. Además, se observó un descenso significativo del GABA con la administración crónica. Estos resultados experimentales sustentan la hipótesis de que la administración de cocaína produce efectos excitadores, posiblemente, a través del incremento de las actividades glutaaspartatérgicas o a través de una disminución de actividad GABAérgica en el núcleo accumbens y en el hipocampo.

  15. Importancia dopaminérgica en farmacodinamia de cocaína evaluada por alteraciones de GABA y glutamato en el núcleo accumbens de ratas

    Directory of Open Access Journals (Sweden)

    Edgar A. Gélvez

    1996-06-01

    Full Text Available Este trabajo se propuso demostrar la importancia del sistema dopaminérgico en la farmacodinamia de cocaína en el SNC de ratas. Este postulado se verificó evaluando las alteraciones de GABA y glutamato en el núcleo accumbens. Este enfoque se sustenta en la gran cantidad de evidencias que muestran, consistentemente alteraciones en la actividad dopaminérgica por cocaína. Además, el GABA y el glutamato tienen gran importancia en los efectos agudos y crónicos por cocaína. Es bien conocida la interrelación de GABA y glutamato con la actividad dopaminérgica en el núcleo accumbens. Se diseñó un estudio por 16 días de administración de cocaína a ratas a la dosis inicial de 30 mglkgldía (IP con incremento de 5 mglkg cada 4 días, a las cuales se les había lesionado la actividad dopaminérgica en el núcleo accumbens con la neurotoxina 6- hidroxidopamina en ácido ascórbico. Además, se conformó un grupo basal que recibió estereotáxicamante, en el núcleo accumbens, ácido ascórbico en solución salina 0,9% y se trató con un volumen correspondiente de solución salina (IP y, un grupo control, al cual estereotáxicamente, en el núcleo mencionado, se le administró 6-OHDA (en ácido ascórbico, recibiendo posteriormente como tratamiento solución salina (IP. La determinación de los niveles de GABA y glutamato se realizó por métodos enzimáticos. Se observó que la administración crónica de cocaína produce una disminución significativa en el nivel de GABA en el núcleo accumbens del grupo problema, con relación a los grupos basal y control. En tanto, el nivel de glutamato en el grupo problema mostró un incremento significativo con relación al grupo basal, pero, no con relación al grupo control. En conclusión, los resultados de este trabajo sostienen la hipótesis del papel importante que tiene la dopamina en la farmacoterapia de cocaína a través de las alteraciones en los niveles de GABA y glutamato o alteraciones en

  16. Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatment.

    Science.gov (United States)

    Ladas, S D; Kamberoglou, D; Karamanolis, G; Vlachogiannakos, J; Zouboulis-Vafiadis, I

    2013-01-01

    Gastric phytobezoars represent the most common bezoars in patients with poor gastric motility. A variety of dissolution therapies and endoscopic fragmentation techniques have been evaluated as conservative treatment so as to avoid surgery. To investigate the effectiveness of Coca-Cola for gastric phytobezoars dissolution. We performed a systematic search to identify publications on gastric phytobezoars to assess the efficacy of Coca-Cola as a dissolution therapy. Diospyrobezoars, formed after persimmon ingestion, are a distinct type of phytobezoars characterized by their hard consistency. Thus, these two subgroups of bezoars were compared in terms of successful dissolution. Over a 10-year period (2002-2012), 24 papers including 46 patients have been published. In 91.3% of the cases, phytobezoar resolution with Coca-Cola administration was successful, either as a single treatment (50%) or combined with further endoscopic techniques, whereas only 4 patients underwent surgery. Phytobezoars were more likely to dissolve after initial attempt with Coca-Cola compared with diospyrobezoars (60.6% vs. 23%, P = 0.022). Coca-Cola alone is effective in gastric phytobezoar dissolution in half of the cases and, combined with additional endoscopic methods, is successful in more than 90% of them. © 2012 Blackwell Publishing Ltd.

  17. Happing: Nativos digitales al servicio de la imagen corporativa de Coca-Cola

    Directory of Open Access Journals (Sweden)

    Carmen Llorente Barroso

    2012-04-01

    Full Text Available Happing, la comunidad de la gente que se atreve a ser feliz, es la nueva propuesta de la compañía Coca-Cola para su promoción web en España; su éxito entre los nativos digitales pone de manifiesto el acierto de esta gran marca internacional, que ha sabido aprovechar la creatividad de los nativos digitales que participan en la comunidad, para dar brillo a una Imagen Corporativa Intencional de sobra solvente. Los nativos digitales que contribuyen a la creación del mágico mundo Coca-Cola, participan gustosos de la oportunidad expresiva que les brida la compañía, fascinados por la filosofía de vida que siempre ha sido bandera de la Imagen de marca de Coca-Cola, ahora alimentada y, en parte, creada por esos nativos digitales.

  18. ATRIBUT KEPUASAN KONSUMEN PRODUK MINUMAN RINGAN COCA COLA DI KOTA BANDARLAMPUNG

    Directory of Open Access Journals (Sweden)

    Adrina Yustitia

    2012-12-01

    Full Text Available The Objective of this research is to analyze the attributes that influence Coca Cola customer satisfaction. Gap analysis shows that the priority attributes must be improved performance were: interesting promotion (-0.83, color of the product (0.61, attractive design (-0.59, refill packaging (-0.58 and product safety (-0.08 while the other attributes have accordanced with customer expectations. Importance-Performance Analysis showed the top priority attributes (quadrant A were an interesting campaign, the next priority for the enhanced importance (quadrant C were the product color, attractive design, packaging, rechargeable and affordable prices. Coca Cola has been able to meet consumer expectations in reaching the level of satisfaction ( multi-attribute test : 1.78, total value of satisfaction (13,508. Keywords: attributes, coca cola, consumer expectations

  19. Geographically Sourcing Cocaine’s Origin - Delineation of the Nineteen Major Coca Growing Regions in South America

    Science.gov (United States)

    Mallette, Jennifer R.; Casale, John F.; Jordan, James; Morello, David R.; Beyer, Paul M.

    2016-03-01

    Previously, geo-sourcing to five major coca growing regions within South America was accomplished. However, the expansion of coca cultivation throughout South America made sub-regional origin determinations increasingly difficult. The former methodology was recently enhanced with additional stable isotope analyses (2H and 18O) to fully characterize cocaine due to the varying environmental conditions in which the coca was grown. An improved data analysis method was implemented with the combination of machine learning and multivariate statistical analysis methods to provide further partitioning between growing regions. Here, we show how the combination of trace cocaine alkaloids, stable isotopes, and multivariate statistical analyses can be used to classify illicit cocaine as originating from one of 19 growing regions within South America. The data obtained through this approach can be used to describe current coca cultivation and production trends, highlight trafficking routes, as well as identify new coca growing regions.

  20. 75 FR 64743 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-10-20

    ... Phenylacetone (8501) II Coca Leaves (9040) II Thebaine (9333) II Opium, raw (9600) II Noroxymorphone (9668) II... re-registration to import crude opium, poppy straw, concentrate of poppy straw, and coca leaves. As... such basic classes of controlled substances listed in schedule I or II, which fall under the authority...

  1. 76 FR 39123 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-07-05

    ... Carfentanil (9743) II Coca Leaves (9040) II Cocaine (9041) II Codeine (9050) II Dextropropoxyphene, bulk (non... registration or re-registration to import crude opium, poppy straw, concentrate of poppy straw, and coca leaves... such basic classes of controlled substances listed in schedule I or II, which fall under the authority...

  2. A pausa que refresca... Tempo e espaço nas propagandas da Coca-Cola

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Furquim de Campos

    2004-01-01

    Full Text Available

    Com base nas reflexões de Mikhail Bakhtin (1988 sobre cronótopo e nos estudos dos semióticos, principalmente no que tange ao percurso passional do sujeito, analisamos propagandas impressas e comerciais televisivos da Coca-Cola. O objetivo principal é traçar a trajetória discursiva da Coca-Cola desde sua entrada no Brasil, em 1941, até a campanha Gostoso é viver, lançada em 2001. O discurso da Coca-Cola apresenta valores positivos como a alegria, emoção e prazer. Entretanto, são eliminados valores negativos e ocultados interditos, como: Coca-Cola é um produto norte-americano e industrializado, portanto, não é natural, engorda e vicia. Constrói-se, assim, um discurso que privilegia aspectos temáticos voltados para os estados passionais eufóricos (paixão, emoção, alegria. A Coca-Cola também reforça a idéia de que está presente em todo tempo e lugar. Assim, as categorias espaço-temporais são elementos importantes para a construção de sentido de suas propagandas. Reafirmando os mesmos valores e mantendo as categorias cronotópicas para a construção de sentido de suas propagandas, a Coca-Cola consolida a idéia de onipotência, ou seja, ela tem o "poder" de refrescar, trazer alegria, provovar emoção e satisfazer prazeres. Cria-se, assim, um estilo, isto é, uma identidade calcada em categorias divinas, tais como onipresença e onipotência.

  3. Colonic obstruction secondary to sigmoid fecaloma endoscopically resolved with Coca-Cola®

    Directory of Open Access Journals (Sweden)

    Guillermo Ontanilla-Clavijo

    Full Text Available Background: Colonic obstruction is a relatively common condition in emergency care, with a mortality rate of up to 20%. In 90% of cases it results from colonic or rectal adenocarcinoma, volvulus, or stenosis secondary to diverticular disease. When fecal impaction is the underlying cause, the condition is usually managed conservatively, but may on occasion become complicated and even require surgical intervention. Based on the proven efficacy of Coca-Cola® to dissolve gastric phytobezoars, we report a case of colonic obstruction secondary to sigmoid fecaloma. Case report: A 58 years old woman arrived at the Emergency Room (ER with persistent constipation for the last six days. An abdominal CT scan showed a large fecal mass at the sigmoid colon with retrograde dilated colonic loops. Cleansing enemas and oral lactulose were administered, which failed to resolve the clinical presentation, so we then proceeded to inject Coca-Cola® within the fecaloma using a sclerosing needle, and then washed the fecaloma surface also with Coca-Cola®. After a few minutes we started to fragment the fecalith, the consistency of which had been notably decreased. Discussion: The use of Coca-Cola® for gastric washes in the management of phytobezoars is well established. Since fecaliths are partly composed of these same substances than phytobezoars, the use of Coca-Cola® might well be warranted against them as in our patient, without surgery. Our case report is the second one published in the literature, in which Coca-Cola® helped solve colonic obstruction secondary to fecaloma.

  4. IDENTIFICATION AND IDENTITY OF THE COCA-COLA BRAND LEXICAL FIELDS

    Directory of Open Access Journals (Sweden)

    Mărioara VLIONCU

    2012-12-01

    Full Text Available Cet article traite un problème très actuel dans le domaine de la linguistique, notamment les champs lexicaux. L’article démontre le fait que les champs lexicaux du brand “ Coca-Cola” se trouve à la frontière entre le langage commun et le langage de spécialité. Le but de l’article est de mettre en évidence les particularités des champs lexicaux des slogans du brand “Coca-Cola”. Le corpus analysé comprend des slogans du brand « Coca-Cola » à partir du XIXème siècle jusqu’au début du XXIème siècle. L’article délimite un cadre théorique et une démonstration pratique concernant les éléments distinctifs des champs lexicaux du brand « Coca-Cola ».Dans ce sens l’article présente et développe le problème des relations entre les champs lexicaux homogènes et hétérogènes, les micro champs lexicaux des slogans du brand « Coca-Cola » les éléments centraux et périphériques des champs lexicaux des slogans de ce brand, les structures syntagmatiques et paradigmatiques des champs lexicaux du brand « Coca-Cola ». L’article met en évidence des champs corrélatifs, multimodaux, pluridimensionnels, en série, récursifs etc. La prémisse dont on est parti a été celle que « jusqu'à présent le problème des champs lexicaux du brand « Coca-Cola » n’a pas été analysé en détail ».Cet article propose une perspective explicative et démonstrative de ces champs lexicaux à l’intention de contribuer à la réalisation d’une analyse linguistique pertinente concernant les champs lexicaux des slogans du brand américain « Coca-Cola ».

  5. The Image and Politics of Coca-Cola: From the Early Years to the Present

    OpenAIRE

    Al-Othman, Dalia

    2001-01-01

    This paper examines the history of Coca-Cola from its early years to the present and discusses how the Company perpetuated the various images it sought for Coke through brilliant leadership, marketing, and the manipulation of events, and how it was able to develop and use its political connections to overcome government-created obstacles and cultural resistance to its products both within and without the United States. The paper will discuss the history of Coca-Cola’s inter...

  6. Importancia de la resiliencia e inteligencia emocional en el consumo de cocaína

    OpenAIRE

    Martínez López, Ana

    2016-01-01

    Según los datos epidemiológicos disponibles, 14.1 millones de europeos adultos consumieron cocaína alguna vez en sus vidas(OED 2012). En la actualidad, ningún tratamiento farmacológico ha sido considerado eficaz para tratar la dependencia a la cocaína, sin embargo algunos tratamientos psicológicos han encontrado resultados positivos en el tratamiento de esta adicción. En este trabajo de investigación se utilizó una muestra de 101 sujetos que acudían a la Unidad de Conductas Adictivas de...

  7. Coca-Cola, caffeine, and mental deficiency: Harry Hollingworth and the Chattanooga trial of 1911.

    Science.gov (United States)

    Benjamin, L T; Rogers, A M; Rosenbaum, A

    1991-01-01

    Harry Hollingworth's 1911 investigation of the behavioral effects of caffeine is one of the earliest examples of psychological research contracted by a large corporation. The research was necessitated by a federal government suit against the Coca-Cola Company for marketing a beverage with a deleterious ingredient, namely, caffeine. Although Hollingworth's research played little role in the outcome of the Coca-Cola trials, it was important as a model of sophistication in experimental design. As such, it set a standard for psychopharmacological research. It also was particularly important in directing Hollingworth toward a life-long career in applied psychology.

  8. Pepsi and Coca Cola in Delhi, India: availability, price and sales.

    Science.gov (United States)

    Taylor, Fiona C; Satija, Ambika; Khurana, Swati; Singh, Gurpreet; Ebrahim, Shah

    2011-04-01

    India is experiencing increased consumption of sugar-sweetened carbonated drinks, consumption that may be associated with increased risk of type 2 diabetes and obesity. The aim of the study was to determine the availability, price and quantity sold of 'Pepsi' and 'Coca Cola' in their 'regular' and 'diet' forms in Delhi and London. A questionnaire about the availability, price and quantity sold per day of both regular and diet Pepsi and Coca Cola was devised and piloted. Using this, a survey of food and drink outlets within a 100 m radius of randomly selected Metro stations was conducted in both cities. Store vendors, owners and staff of food and drink outlets. Delhi, India; London, United Kingdom. In Delhi, of the outlets stocking regular Pepsi and Coca Cola, only 34% sold diet versions and these were more readily available in the most affluent areas than in the poorest areas (34% v. 6%, Z=3.67, PCoca Cola was observed in Delhi; however, profit margins were better for regular, relative to diet, Coca Cola. Sales of regular products were significantly greater than those of diet products (PCoca Cola in less affluent areas of Delhi is likely to exacerbate the obesity and diabetes trends. Price differentials to promote diet versions and other healthier or traditional low-energy drinks may be beneficial.

  9. Stimulatory effect of Coca-Cola on gastroduodenal HCO3- secretion in rats.

    Science.gov (United States)

    Sasaki, Y; Aihara, E; Ise, F; Kita, K; Takeuchi, K

    2007-10-01

    We examined the effect of various carbonated beverages, especially Coca-Cola, on the HCO3- secretion in the rat stomach and duodenum. Under urethane anaesthesia, a chambered stomach or a proximal duodenal loop was perfused with saline, and HCO3- secretion was measured at pH 7.0 using a pH-stat method and by adding 2 mM HCl. The amount of CO2 contained in these beverages was about 4-7 g/mL. Coca-Cola topically applied to the mucosa for 10 min significantly increased the HCO3- secretion in both the stomach and the duodenum. The HCO3- response in the duodenum was totally abolished by indomethacin and also partially inhibited by acetazolamide, an inhibitor of carbonic anhydrase. Likewise, the response in the stomach was also markedly inhibited by either acetazolamide or indomethacin. The mucosal application of Coca-Cola increased the PGE2 contents in both the stomach and the duodenum. Other carbonated beverages, such as sparkling water, Fanta Grape or cider, also increased the HCO3- secretion in these tissues. These results suggest that Coca-Cola induces HCO3- secretion in both the stomach and the duodenum, and these responses may be attributable to both the intracellular supply of HCO3- generated via carbonic anhydrase, and endogenous PGs, probably related to the acidic pH of the solution.

  10. Coca-Cola jõulukaravan tõi lastekodulastele palju rõõmu

    Index Scriptorium Estoniae

    2007-01-01

    Vt. ka Linnaleht : Tartu 21. dets., lk. 13, Linnaleht : Pärnu 21. dets., lk. B5. Sel nädalal Eestis ringi sõitnud heategevuslik Coca-Cola jõulukaravan viis kingitusi 17 Tartu ja Tartumaa, Tallinna, Jõgevamaa ning Ida-Virumaa lastekodusse

  11. Coca-Cola Valued Youth Program. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2009

    2009-01-01

    The Coca-Cola Valued Youth Program offers secondary school students who are considered at risk of dropping out the opportunity to serve as tutors in elementary schools. By having these at-risk students serve as tutors, the program aims to improve their basic academic skills and self-esteem, with the goal of keeping them enrolled in school. The…

  12. SUSTAINABLE DEVELOPMENT – AN IMPERATIVE OF INDUSTRIAL COMPANIES. CASE STUDY: COCA-COLA HBC ROMANIA

    Directory of Open Access Journals (Sweden)

    Catalin POPESCU

    2015-06-01

    Full Text Available The paper begins with a summary of the concept, emphasizing that sustainable development is a strongly supported policy around the world. The case study examines specific aspects of sustainable development in Coca-Cola HBC Romania. Finally it presents the main obstacles and opportunities identified for adoption by Romanian companies in their business of sustainable competitiveness strategies.

  13. Valuing Brazilian Youth: IDRA's Coca Cola Valued Youth Program in Latin America

    Science.gov (United States)

    Montecel, Maria Robledo

    2008-01-01

    Intercultural Development Research Association (IDRA) is an independent, non-profit organization with a vision for schools that work for all children. It partnered with Coca-Cola in 1984 and began a dropout prevention program just as it was conducting the first comprehensive study of school dropouts in Texas. Its annual studies since then have…

  14. 21 CFR 1304.32 - Reports of manufacturers importing coca leaves.

    Science.gov (United States)

    2010-04-01

    ... manufacturer importing or manufacturing from raw coca leaves shall submit information accounting for the importation and for all manufacturing operations performed between the importation and the manufacture of bulk or finished products standardized in accordance with U.S. Pharmacopoeia, National Formulary, or other...

  15. SUSTAINABLE DEVELOPMENT – AN IMPERATIVE OF INDUSTRIAL COMPANIES. CASE STUDY: COCA-COLA HBC ROMANIA

    OpenAIRE

    Catalin POPESCU; Mihaela OTELEA

    2015-01-01

    The paper begins with a summary of the concept, emphasizing that sustainable development is a strongly supported policy around the world. The case study examines specific aspects of sustainable development in Coca-Cola HBC Romania. Finally it presents the main obstacles and opportunities identified for adoption by Romanian companies in their business of sustainable competitiveness strategies.

  16. Komunikasi Pemasaran Produk Big-Cola Dan Coca-Cola Terhadap Minat Beli Konsumen (Studi Komparatif Komunikasi Pemasaran Produk Big-Cola Dan Coca-Cola Terahadap Minat Beli Konsumen Pada Mahasiswa Di Universitas Sumatera Utara )

    OpenAIRE

    Harahap, Mirza swardani

    2015-01-01

    Research is called communication of its marketing Big-Cola and Coca-Cola to interest in buying types of buyers in student at the university of north sumatra.The purpose of this research to know the influence of communication of its marketing Big-Cola and Coca-Cola to interest in buying student at the university of north sumatra. A study of correlational to perceive the difference or comparative marketing communications Big-Cola products and Coca-Cola to interest in buying types of buyers in s...

  17. Efectos toxicológicos y neuropsiquiátricos producidos por consumo de cocaína

    OpenAIRE

    Téllez Mosquera, Jairo; Cote Menéndez, Miguel

    2014-01-01

    Este artículo realiza una revisión sobre la historia, la cultura, los aspectos clínico toxicológicos y los efectos en el comportamiento producidos por el uso agudo y crónico de la cocaína. La cocaína como sustancia psicoactiva sin importar su forma de consumo, una vez dentro del organismo sigue las mismas vías metabólicas, produciendo efecto sobre los diferentes órganos. La toxicidad de la cocaína es debida a su metabolito el benzoilecgonina un potente agonista a...

  18. Lesión de paladar duro por uso crónico de cocaína. Reporte de un caso

    Directory of Open Access Journals (Sweden)

    José Luis D’Addino

    2014-09-01

    Full Text Available El objetivo de este trabajo fue presentar una lesión inusual de gran tamaño comprometiendo paladar duro. Se describe su diagnóstico, manejo terapéutico y evolución. El paciente de raza blanca de 37 años, desde hace 12 meses presentaba lesión ulcerada con perforación de paladar duro. Dentro de los antecedentes personales se resalta el uso de cocaína desde hace 20 años, tabaquista desde hace 23 años. Como antecedentes familiares de importancia cabe citarse 2 casos de Hipertermia Maligna en familiares consanguíneos operados anteriormente. La biopsia de la lesión fue lesión benigna. Se intervino quirúrgicamente efectuándose un colgajo tipo Randal para el cierre del defecto y Rintala para la cobertura de la cara nasal del orificio. Se reforzó con malla de colágeno entre los dos colgajos. El último control a los 6 meses de seguimiento, mostraba buena evolución post quirúrgica aunque recayó en el consumo de cocaína y no regresó a la consulta. En conclusión, el uso crónico de cocaína suele destruir el tabique nasal y el paladar. La reparación resulta un desafió por lo dificultoso de la obtención de tejidos sumado a la escasa adhesión de los enfermos al abandono de la droga.

  19. 78 FR 12101 - Importer of Controlled Substances; Notice of Application; Mallinckrodt, LLC.

    Science.gov (United States)

    2013-02-21

    ... Coca Leaves (9040) II Opium, raw (9600) II Poppy Straw Concentrate (9670) II The company plans to... or coca leaves. Comments and requests for hearings on applications to import narcotic raw material... to manufacture such basic classes of controlled substances listed in schedules I or II, which fall...

  20. Developing Industry-Sponsored Entrepreneurship Education Programmes. The Experiences of the Coca-Cola National Enterprise Award.

    Science.gov (United States)

    Henry, Colette; Titterington, Albert; Wiseman, Kate

    1998-01-01

    A partnership among Dundalk Institute of Technology (Ireland), Coca Cola, and government encourages young entrepreneurs through formal education in business management, workshops, mentoring, and financial rewards provided by the corporation's National Enterprise Award. (SK)

  1. Huge gastric diospyrobezoars successfully treated by oral intake and endoscopic injection of Coca-Cola.

    Science.gov (United States)

    Chung, Y W; Han, D S; Park, Y K; Son, B K; Paik, C H; Jeon, Y C; Sohn, J H

    2006-07-01

    A diospyrobezoar is a type of phytobezoar that is considered to be harder than any other types of phytobezoars. Here, we describe a new treatment modality, which effectively and easily disrupted huge gastric diospyrobezoars. A 41-year-old man with a history of diabetes mellitus was admitted with lower abdominal pain and vomiting. Upper gastrointestinal endoscopy revealed three huge, round diospyrobezoars in the stomach. He was made to drink two cans of Coca-Cola every 6 h. At endoscopy the next day, the bezoars were partially dissolved and turned to be softened. We performed direct endoscopic injection of Coca-Cola into each bezoar. At repeated endoscopy the next day, the bezoars were completely dissolved.

  2. La coca en el intercambio mercante Atlántico-Mediterráneo

    Directory of Open Access Journals (Sweden)

    Ortega Villoslada, Antonio

    2008-06-01

    Full Text Available One approaches the passage of the coca to the Mediterranean and its relevancy in the medieval navigation. Superiority determined by the rudder of sternpost, know generically by the sailors of the mediterranean basin as bayonés, that is to say, of the Gulf of Biscay, whose skippers will arrive regularly to Majorca.

    Se aborda el paso de la coca al Mediterráneo y su relevancia en la náutica medieval. Primacía determinada por el timón de codaste, conocido genéricamente por los marinos de la cuenca mediterránea como bayonés, es decir, del Golfo de Vizcaya, cuyos patrones arribarán regularmente a Mallorca.

  3. Duodenal pH in health and duodenal ulcer disease: effect of a meal, Coca-Cola, smoking, and cimetidine.

    Science.gov (United States)

    McCloy, R F; Greenberg, G R; Baron, J H

    1984-04-01

    Intraluminal duodenal pH was recorded using a combined miniature electrode and logged digitally every 10 or 20 seconds for five hours (basal/meal/drink) in eight control subjects and 11 patients with duodenal ulcer (five on and off treatment with cimetidine). Over the whole test there were no significant differences in duodenal mean pH or log mean hydrogen ion activity (LMHa) between control subjects and patients with duodenal ulcer, but there were significantly longer periods of duodenal acidification (pH less than 4) and paradoxically more periods of duodenal alkalinisation (pH greater than 6) in the duodenal ulcer group compared with controls. After a meal duodenal mean pH and LMHa fell significantly in both controls and patients with duodenal ulcer, with more periods of duodenal acidification and alkalinisation in the duodenal ulcer group. An exogenous acid load (Coca-Cola) significantly increased the periods of duodenal acidification, and reduced alkalinisation, in both groups. Cimetidine significantly increased mean pH and LMHa and abolished the brief spikes of acidification in four of five patients with duodenal ulcer. Peak acid output (but not basal acid output) was significantly correlated with duodenal mean pH and LMHa but not with the periods of duodenal acidification. Smoking did not affect duodenal pH in either group.

  4. The Dimension Of The Socio-Cultural Brand Of Coca-Cola

    Directory of Open Access Journals (Sweden)

    Florentina Manuela Dumitrescu

    2016-12-01

    Full Text Available Today, advertising is undoubtedly one of the most fascinating social phenomena, a fundamental factor influencing individuals, attitudes or lifestyles. It is an important element of contemporary culture, deeply anchored in our cultural heritage. In this framework encompasses our article, aiming to demonstrate influential aspects of the Coca-Cola advertising slogan as an instrument of culture and ideology, in a few words, a merciless mirror of our society.

  5. An Economic Analysis of Brand-Level Strategic Pricing Between Coca-Cola Company and Pepsi

    OpenAIRE

    Dhar, Tirtha; Chavas, Jean- Paul; Cotterill, Ronald W.; Gould, Brian W.

    2005-01-01

    We investigate market structure and strategic pricing for leading brands sold by Coca-Cola Company and PepsiCo. in the context of a flexible demand specification (i.e., nonlinear AIDS) and structural price equations. Our flexible and generalized approach does not rely upon the often used ad hoc linear approximations to demand and profit-maximizing first-order conditions, andthe assumption of Nash-Bertrand competition. We estimate a conjectural variation model and test for different brand-leve...

  6. Corporate Brand Value Shifting from Identity to Innovation Capability: from Coca-Cola to Apple

    OpenAIRE

    Ray R. Gehani

    2016-01-01

    Corporate brand value, a key corporate asset, has traditionally relied on stakeholder interactions, heritage, and corporate identity. In dynamic fast clock-speed industries (information technology and consumer electronics), we note that brand values change dramatically within a few years based on their innovativeness. Using grounded theory approach and multi-case study method we examine how Apple, Samsung, Toyota, and Coca-Cola sustained their most valuable global brands while Kodak and Gener...

  7. Institutional Advertising in the Context of Social Representation Theory: The Case of Coca Cola

    OpenAIRE

    MURAT ÇOLPA, Zeynep

    2018-01-01

    Social representation emergesto provide needs of individuals understanding world. Production of socialrepresentations only can be provided by individuals and groups interact eachother that is generally used in the field of communication. In this respect,this study attempts to analyze the instituional advertising in the context ofsocial representation theory. In this study institutionaladvertising of Coca Cola which is a well-known beverage company is inspectedand evaluated. Three sample of Co...

  8. Measuring the Effectiveness of Sales Promotion Activities on Brand Loyalty: A Study on COCA COLA

    OpenAIRE

    Uma Shankar Singh; Osman Sahin

    2017-01-01

    The study is descriptive in nature measuring the effect and relationship in between sales promotion activities and brand loyalty. The study is done on COCA COLA brand in the open market. The research problem observed here as to measure the efficiency of sales promotion and brand loyalty to get the real effectiveness on sales promotion activities. The research objectives formulated are to know the importance of component of sales promotion activities, to know the effect of advertising on sales...

  9. An Econometric Analysis of Brand Level Strategic Pricing Between Coca Cola and Pepsi Inc.

    OpenAIRE

    Tirtha Pratim Dhar; Jean-Paul Chavas; Ronald W. Cotterill; Brian W. Gould

    2002-01-01

    Market structure and strategic pricing for leading brands sold by Coca Cola and Pepsi Inc. are investigated in the context of a flexible demand specification and structural price equations. This approach is more general than prior studies that rely upon linear approximations and interactions of an inherently nonlinear problem. We test for Bertrand equilibrium, Stackelberg equilibrium, collusion, and a general conjectural variation (CV) specification. This nonlinear Full Information Maximum Li...

  10. Coca-Cola, cancers, and coronaries: personality and stress as mediating factors.

    Science.gov (United States)

    Grossarth-Maticek, R; Eysenck, H J

    1991-06-01

    A theory is presented relating the consumption of stimulant and depressant drugs to cancer and coronary heart disease, with stress/personality acting as an intermediary. The predictions from the theory that large-scale consumption of Coca-Cola would prevent cancer and promote coronary heart disease was tested and found to be supported by the results of a long-scale prospective study. Results replicate those from an earlier study using coffee as a stimulant drug.

  11. An internalization approach to joint ventures: the case of Coca-Cola in China

    OpenAIRE

    Mok, Vincent; Dai, Xiudian; Yeung, Godfrey

    2002-01-01

    In the presence of high transaction costs due to market imperfections, it is normally less expensive for multinational corporations (MNCs) to conduct their business activities in new markets through their internal corporate structures rather than by relying on the markets. Based on a case study of Coca-Cola's entry into the Chinese market, this paper tests the applicability of internalization theory to explaining the entry mode choices of MNCs in developing countries. Internalization theory r...

  12. Analýza komunikačního mixu společnosti Coca Cola na českém trhu

    OpenAIRE

    Málková, Alena

    2011-01-01

    The subject of this diploma thesis is the communications mix of The Coca-Cola Company and it is focusing on the brand Coca-Cola on the Czech market. The aim is to analyze current communication mix of brand Coca-Cola, reveal fundamental aspects that influence the communication mix and propose specific changes to the mix. Introductory part acquaints readers with the various communication tools, their advantages and disadvantages, the optimal structure of the communication mix and other theoreti...

  13. The use of Coca-Cola in the management of bolus obstruction in benign oesophageal stricture.

    Science.gov (United States)

    Karanjia, N. D.; Rees, M.

    1993-01-01

    Oesophageal stricture is a complication of oesophageal reflux and may itself be complicated by bolus obstruction. We reviewed the records of patients presenting with dysphagia and who were found to have benign oesophageal strictures. We studied the outcome of bolus obstruction in 13 episodes affecting eight patients. In six episodes Coca-Cola was administered on the day before endoscopy, and in all these patients the bolus had cleared. In seven episodes nothing was administered before endoscopy, and in all seven a bolus was evident at endoscopy. In five of these seven the bolus was removed piecemeal and in each of these instances the endoscope had to be passed between two and five times. In the remaining two instances the procedure was abandoned and the patients returned to the ward for the administration of Coca-Cola. At subsequent endoscopy these patients were found to be clear of any bolus. These results suggest that the administration of Coca-Cola (or other aerated drinks) may clear a bolus in the acutely obstructed oesophagus. PMID:8476194

  14. ["Fabulous things". Drug narratives about coca and cocaine in the 19th century].

    Science.gov (United States)

    Wahrig, Bettina

    2009-12-01

    This contribution focuses on the history of Coca leaves and Cocaine in the second half of 19th century Europe. Even though, to date, no direct link has been established between the activities of the Milano physician Paolo Mantegazza, and the Göttingen chemist Friedrich Wöhler, it is not a mere coincidence that both published their findings in the same year, namely, 1859. Mantegazza authored the first treatise claiming that Coca had psychoactive qualities and touted its broad therapeutic faculties; he claimed that it should be introduced into European pharmacotherapy. In Wöhler's laboratory, cocaine was isolated from leaves by his pupil Alfred Niemann; later, Wilhelm Lossen refined and corrected Niemann's results. Narratives about medicinal drugs often streamline history into a story that starts with multiple meanings and impure matters and ends with well-defined substances, directed at clear-cut diseases and symptoms. In the case of Coca, however, the pure substance triggered no such process well into the 1880s, whereas the leaves continued to circulate as an exotic, pluripotent drug whose effects where miraculous and yet difficult to establish.

  15. Cocaína: lendas, história e abuso Cocaine: myths, history and abuse

    Directory of Open Access Journals (Sweden)

    Pedro Eugênio M Ferreira

    2001-06-01

    Full Text Available A civilização ocidental tem estado envolvida com múltiplos problemas sociais, sendo o abuso de drogas um deles. A cocaína e os transtornos decorrentes de seu abuso tornaram-se um problema de saúde pública. O presente trabalho tem como objetivo colaborar pelo aprofundamento da investigação histórica desse tema. Há mais de 4500 anos, as folhas de coca são usadas por índios da América do Sul. Com a industrialização no século XIX, a cocaína chegou aos países desenvolvidos da época. Na medicina, essa substância também se mostrou presente, sendo usada, tanto por Freud quanto por outros médicos, na tentativa de curar inúmeras enfermidades. No entanto, a maior disponibilidade e a queda dos preços nos últimos 30 anos possibilitaram que essa droga fosse usada abusivamente por um número crescente de pessoas, trazendo conseqüências assustadoras para a saúde do indivíduo e para a sociedade como um todo.Western civilization is involved with multiple social problems and drug abuse is one of them. Cocaine and its abuse have become over the years a public health problem. This paper intends to provide a historical background to the subject. For more than 4,500 years, South America natives have been using coca leaves. After the industrial revolution in the 19th century, cocaine clorhydrate, an alkaloid present in the coca leaf, reached the developed countries. Many products, which main ingredient was cocaine, were consumed by famous people at that time, such as Vino Mariani, used by Pope Leo XVIII. In medicine, Freud and other doctors used cocaine with the purpose of healing various diseases. However, in the last 30 years, it became more available and its price dropped, making it accessible to an increasing number of people, resulting in alarming consequences to users' health as well as for the whole society.

  16. 75 FR 69705 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-11-15

    ... re-registration to import crude opium, poppy straw, concentrate of poppy straw, and coca leaves. As... classes of controlled substances listed in schedule I or II, which fall under the authority of section...

  17. 76 FR 14688 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-03-17

    ...-registration to import crude opium, poppy straw, concentrate of poppy straw or coca leaves. As explained in the... controlled substances listed in schedule I or II, which fall under the authority of section 1002(a)(2)(B) of...

  18. 75 FR 65658 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-10-26

    ..., and coca leaves. As explained in the Correction to Notice of Application pertaining to Rhodes... DEA to manufacture such basic classes of controlled substances listed in schedule I or II, which fall...

  19. 76 FR 35241 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-06-16

    ..., and coca leaves. As explained in the Correction to Notice of Application pertaining to Rhodes... DEA to manufacture such basic classes of controlled substances listed in schedule I or II, which fall...

  20. 76 FR 42732 - Importer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-07-19

    ... classes of controlled substances: Drug Schedule Coca Leaves (9040) II Opium, raw (9600) II Poppy Straw... with United States obligations under international treaties, conventions, or protocols in effect on May...

  1. 75 FR 44285 - Importer of Controlled Substances: Notice of Registration

    Science.gov (United States)

    2010-07-28

    ... of controlled substances listed in schedule II: Drug Schedule Coca Leaves (9040) II Opium, raw (9600... treaties, conventions, or protocols in effect on May 1, 1971, at this time. DEA has investigated Penick...

  2. Science organisations and Coca-Cola's 'war' with the public health community: insights from an internal industry document.

    Science.gov (United States)

    Barlow, Pepita; Serôdio, Paulo; Ruskin, Gary; McKee, Martin; Stuckler, David

    2018-03-14

    Critics have long accused food and beverage companies of trying to exonerate their products from blame for obesity by funding organisations that highlight alternative causes. Yet, conclusions about the intentions of food and beverage companies in funding scientific organisations have been prevented by limited access to industry's internal documents. Here we allow the words of Coca-Cola employees to speak about how the corporation intended to advance its interests by funding the Global Energy Balance Network (GEBN). The documents reveal that Coca-Cola funded and supported the GEBN because it would serve as a 'weapon' to 'change the conversation' about obesity amidst a 'growing war between the public health community and private industry'. Despite its close links to the Coca-Cola company, the GEBN was to be portrayed as an 'honest broker' in this 'war'. The GEBN's message was to be promoted via an extensive advocacy campaign linking researchers, policy-makers, health professionals, journalists and the general public. Ultimately, these activities were intended to advance Coca-Cola's corporate interests: as they note, their purpose was to 'promote practices that are effective in terms of both policy and profit'. Coca-Cola's proposal for establishing the GEBN corroborates concerns about food and beverage corporations' involvement in scientific organisations and their similarities with Big Tobacco. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  3. Caffeine enhances and accelerates the expression of sensitization induced by coca paste indicating its relevance as a main adulterant.

    Science.gov (United States)

    Prieto, José P; Galvalisi, Martín; López-Hill, Ximena; Meikle, María N; Abin-Carriquiry, Juan A; Scorza, Cecilia

    2015-08-01

    Caffeine is an active adulterant found in several drugs of abuse including coca paste (CP). We had previously demonstrated that caffeine potentiated the acute stimulant effect induced by CP seized samples. The role of caffeine in the expression of sensitization elicited by a CP seized sample (CP1) was here evaluated. CP1 (equivalent dose of 10 mg/kg of cocaine), cocaine (pure, 10 mg/kg), a combination of cocaine 10 mg/kg plus caffeine 2.5 mg/kg (CP1-surrogate) and saline (control) were intraperitoneally injected in male rats under two different sensitization schedules. Ambulatory locomotion was recorded in 58 animals. After five daily CP1 injections and 5 days of withdrawal, CP1-challenged animals displayed a more robust sensitization than cocaine-treated animals. When a 3 injections-regime of CP1-surrogate or cocaine was assayed, only CP1-surrogate was able to elicit sensitization. Caffeine enhances and accelerates the CP1-induced sensitization. Results may shed light on the fast and high dependence observed in CP users. © American Academy of Addiction Psychiatry.

  4. Marit Kroon: just for fun pole mõtet Coca-Colas töötada / Marit Kroon ; intervjueerinud Taivo Paju

    Index Scriptorium Estoniae

    Kroon, Marit

    2010-01-01

    Coca-Cola Eesti esinduses kogu Baltikumi turunduse eest vastutav Marit Kroon vastab küsimustele, mis puudutavad Coca-Colasse tööle saamist, esimesi tööülesandeid, töötamist ülemustest eemal, enese motiveerimist, enesekehtestamist ning valmisolekut kodust eemal töötamiseks

  5. Differential effects of dopamine and opioid receptor blockade on motivated Coca-Cola drinking behavior and associated changes in brain, skin and muscle temperatures.

    Science.gov (United States)

    Kiyatkin, E A

    2010-05-05

    Although pharmacological blockade of both dopamine (DA) and opiate receptors has an inhibiting effect on appetitive motivated behaviors, it is still unclear which physiological mechanisms affected by these treatments underlie the behavioral deficit. To clarify this issue, we examined how pharmacological blockade of either DA (SCH23390+eticlopride at 0.2 mg/kg each) or opioid receptors (naloxone 1 mg/kg) affects motor activity and temperature fluctuations in the nucleus accumbens (NAcc), temporal muscle, and facial skin associated with motivated Coca-Cola drinking behavior in rats. In drug-free conditions, presentation of a cup containing 5 ml of Coca-Cola induced locomotor activation and rapid NAcc temperature increases, which both transiently decreased during drinking, and phasically increased again after the cup was emptied. Muscle temperatures followed this pattern, but increases were weaker and more delayed than those in the NAcc. Skin temperature rapidly dropped after cup presentation, remained at low levels during consumption, and slowly restored during post-consumption behavioral activation. By itself, DA receptor blockade induced robust decrease in spontaneous locomotion, moderate increases in brain and muscle temperatures, and a relative increase in skin temperatures, suggesting metabolic activation coupled with adynamia. Following this treatment (approximately 180 min), motor activation to cup presentation and Coca-Cola consumption were absent, but rats showed NAcc and muscle temperature increases following cup presentation comparable to control. Therefore, DA receptor blockade does not affect significantly central and peripheral autonomic responses to appetitive stimuli, but eliminates their behavior-activating effects, thus disrupting appetitive behavior and blocking consumption. Naloxone alone slightly decreased brain and muscle temperatures and increased skin temperatures, pointing at the enhanced heat loss and possible minor inhibition of basal

  6. Sangue e Coca-Cola: a carnavalização e a literatura pop de Roberto Drummond

    Directory of Open Access Journals (Sweden)

    Ernest Bowes

    2018-04-01

    Full Text Available Este estudo se propõe à reflexão sobre as obras de Roberto Drummond, mais especificamente Sangue de Coca-Cola - romance que integra o ciclo Coca-Cola do autor. A pesquisa se propõe a demonstrar que a arte pop não é estática e que se materializa através da interação com outras linguagens e com a cultura. Assim, o trânsito entre distintos campos discursivos como a Filosofia, Sociologia e a Teoria da Literatura apresentou-se, então, como a estratégia mais apropriada para discutir a questão.   Palavras-chave: Carnavalização, Literatura Pop, Sangue de Coca-Cola.

  7. Intoxicaciones agudas por cocaína: Caracterización, factores de riesgo, conocimientos y precauciones de los consumidores

    OpenAIRE

    Santos Sanz, Sara

    2012-01-01

    La cocaína es la tercera droga ilegal más consumida después del cannabis y las anfetaminas. España es uno de los países donde su consumo está más extendido, sobretodo en el grupo de adultos jóvenes de 15-34 años. Los problemas de salud asociados al consumo de cocaína son frecuentes (13%-30%) entre los consumidores, aunque la intoxicación aguda por cocaína así como sus factores de riesgo no se han estudiado tanto como en el caso de la sobredosis por heroina. Existen vacios en la literatura sob...

  8. We are Originarios …"we just aren't from here": coca leaf and identity politics in the Chapare, Bolivia.

    Science.gov (United States)

    Grisaffi, Thomas

    2010-01-01

    This article first examines the ways in which coca leaf acquired an important symbolic value in forging a counter-hegemonic discourse that wove together various strands of class and cultural identity struggles in the Chapare province, Bolivia. The second line of enquiry that runs through this article deals with the conflicts that arose when the coca union mutated into a governing political party. Now that the coca growers' leader, Evo Morales, is President of the Republic he is obliged by the international community to reduce the amount of land under coca cultivation. To do this President Morales has had to rhetorically pull coca leaf apart from Andean tradition. This presents a challenge to the integrity of indigenous-peasant based movements in the Chapare because it brings attention to their constructed nature and thus questions the authenticity of the originario identity.

  9. The influence of "Coca-Cola" company over the quality of the environment of Zemun

    Directory of Open Access Journals (Sweden)

    Topalović Sanja

    2012-01-01

    Full Text Available Food industry can be a significant source of environmental pollution, which depends on the type of food industry. In the industrial area “Gornji Zemun” there are at least ten larger factories. Among these Coca-Cola HBC Serbia, as a representative of the industry of non-alcoholic beverages, is the most active and has the biggest influence on the environment. The success in business is based on the sustainable development and the lesser influence over the environment, which will be proven by this article.

  10. Persimmon bezoar successfully treated by oral intake of Coca-Cola: a case report.

    Science.gov (United States)

    Hayashi, Kazuki; Ohara, Hirotaka; Naitoh, Itaru; Okumura, Fumihiro; Andoh, Tomoaki; Itoh, Takafumi; Nakazawa, Takahiro; Joh, Takashi

    2008-12-11

    An 82-year-old male presented with a chief complaint of upper abdominal pain. Subsequently, a bezoar and a gastric ulcer were detected by upper gastrointestinal endoscopy. The bezoar was dark green in color and extremely hard, having a major axis of 7 cm. After hospitalization, 500-1000 ml/day of Coca-Cola was orally administered continuously for 3 weeks. Thereafter, the bezoar decreased in size to a major axis of 4 cm and showed a softening trend. Therefore, lithotripsy was thereafter carried out under endoscopy using forceps.

  11. Bezoar in a Pediatric Oncology Patient Treated with Coca-Cola.

    Science.gov (United States)

    Naramore, Sara; Virojanapa, Amy; Bell, Moshe; Jhaveri, Punit N

    2015-01-01

    A bezoar is a mass of indigestible material. Bezoars can present with a gradual onset of non-specific gastrointestinal symptoms including abdominal pain, nausea and vomiting. However, bezoars can result in more serious conditions such as intestinal bleeding or obstruction. Without quick recognition, particularly in susceptible individuals, the diagnosis and treatment can be delayed. Currently resolution is achieved with enzymatic dissolution, endoscopic fragmentation or surgery. We describe, to our knowledge, the first pediatric patient with lymphoma to have had a bezoar treated with Coca-Cola.

  12. Bezoar in a Pediatric Oncology Patient Treated with Coca-Cola

    Directory of Open Access Journals (Sweden)

    Sara Naramore

    2015-07-01

    Full Text Available A bezoar is a mass of indigestible material. Bezoars can present with a gradual onset of non-specific gastrointestinal symptoms including abdominal pain, nausea and vomiting. However, bezoars can result in more serious conditions such as intestinal bleeding or obstruction. Without quick recognition, particularly in susceptible individuals, the diagnosis and treatment can be delayed. Currently resolution is achieved with enzymatic dissolution, endoscopic fragmentation or surgery. We describe, to our knowledge, the first pediatric patient with lymphoma to have had a bezoar treated with Coca-Cola.

  13. Oesophageal food impaction in achalasia treated with Coca-Cola and nifedipine.

    Science.gov (United States)

    Koumi, Andriani; Panos, Marios Zenon

    2010-01-01

    Achalasia is characterised by the loss of peristaltic movement in the distal oesophagus and failure of the lower oesophageal sphincter relaxation, which results in impaired oesophageal emptying. We report a case of a 92-year-old frail woman with a history of achalasia, who presented with acute oesophageal obstruction due to impaction of a large amount of food material. She was treated successfully with nifedipine, in combination with Coca-Cola (original product, not sugar free), so avoiding the risks associated with repeated endoscopic intubation and piecemeal removal of the oesophageal content.

  14. La m??sica en la narrativa publicitaria audiovisual. El caso de Coca-Cola

    OpenAIRE

    S??nchez Porras, Mar??a Jos??

    2015-01-01

    En esta investigaci??n se ha realizado un estudio profundo de la m??sica en la publicidad audiovisual y su relaci??n con otros aspectos sonoros y visuales de la publicidad. Para llevarlo a cabo se ha seleccionado una marca concreta, Coca-Cola, debido a su globalizaci??n y reconocimiento. Se ha abordado una nueva perspectiva de an??lisis musical en la publicidad audiovisual, abordando los diferentes elementos de la estructura musical a trav??s de la proyecci??n de los anuncios. Se ha rea...

  15. Cocaína (Investigación bibliográfica)

    OpenAIRE

    Salas Segura, Donato A.

    2001-01-01

    artículo de revisión bibliográfica -- Universidad de Costa Rica, Facultad de Medicina. 2001 Se trata de una revisión bibliográfica sobre las principales características farmacológicas, clínicas y del tratamiento de la intoxicación por cocaína. It is about the bibliographical review of the main pharmacological, clinical characteristics and the treatment of intoxication with cocaine. lt also includes other less frequently studied aspects in the medical literature like the botanical chara...

  16. Intoxicación con cocaína: reporte de caso

    OpenAIRE

    Juan Dávila Meneses

    2013-01-01

    El consumo de cocaína en Costa Rica, en cualquiera de sus presentaciones, es un problema creciente de salud pública y seguridad ciudadana desde la década de los 80’s. Las complicaciones derivadas de su uso tienen un impacto considerable en la utilización del recurso humano y económico de nuestro sistema de salud y cuya complejidad de manejo es clara: se ha asociado en forma muy importante con la muerte súbita en pacientes jóvenes y sin factores de riesgo, que presentan infartos agudos del mio...

  17. ZUNANJE OGLAŠEVANJ NA PRIMERU BLAGOVNE ZNAMKE COCA-COLA

    OpenAIRE

    Justinek, Vanesa

    2016-01-01

    V diplomskem seminarju z naslovom Zunanje oglaševanje na primeru blagovne znamke Coca Cola govorim predvsem o oglasih, ki so izven zaprtih prostorov. Zunanje oglaševanje je oblika tržnega komuniciranja ter plačana oblika oglaševanja, poteka preko sredstev javnega obveščanja. V to obliko oglaševanja sodijo: Veleplakati (jumbo plakati), mali panoji (city panoji), digitalni panoji, polepitve na prevoznih sredstvih, oglasni stebri, transparenti nad voziščem, obešanke, oglasni stolpi. V prvem t...

  18. Activating Processes in the Brand Communication of Valuable Brands on the example of Coca-Cola.

    OpenAIRE

    Pöhler, Marie-Luise

    2017-01-01

    Everyone in the world, from the streets of Paris to the villages in Africa, knows the logo with the white letters that are written on a bright red background. Coca-Cola was introduced in 1886. In that year, only nine glasses of the soda drink were sold per day. So how did the little company from Atlanta become the world’s most valuable and popular soft drink? One of the company’s secrets is its emotional and memorable advertising strategies. Therefore, this thesis explains and analyzes ho...

  19. The influence of "Coca-Cola" company over the quality of the environment of Zemun

    OpenAIRE

    Topalović Sanja

    2012-01-01

    Food industry can be a significant source of environmental pollution, which depends on the type of food industry. In the industrial area “Gornji Zemun” there are at least ten larger factories. Among these Coca-Cola HBC Serbia, as a representative of the industry of non-alcoholic beverages, is the most active and has the biggest influence on the environment. The success in business is based on the sustainable development and the lesser influence over the environment, which will be proven...

  20. Corporate Brand Value Shifting from Identity to Innovation Capability: from Coca-Cola to Apple

    Directory of Open Access Journals (Sweden)

    Ray R. Gehani

    2016-10-01

    Full Text Available Corporate brand value, a key corporate asset, has traditionally relied on stakeholder interactions, heritage, and corporate identity. In dynamic fast clock-speed industries (information technology and consumer electronics, we note that brand values change dramatically within a few years based on their innovativeness. Using grounded theory approach and multi-case study method we examine how Apple, Samsung, Toyota, and Coca-Cola sustained their most valuable global brands while Kodak and General Motors eroded the same. Certain key dynamic innovative capabilities are identified as best practices. We conclude with implications for managers and future researchers, along with some limitations.

  1. Relationship of Coca-Cola Brazil and the communities participant of the social projects: (im) possibilities

    OpenAIRE

    Lima, Vanessa Sobreira Casali

    2014-01-01

    Five years ago, Coca-Cola Brasil launched a program named “Coletivo Project”, with the purpose to enjoy an opportunity of increase on the potential consumption power of the low-income pyramid population that lived on the “favelas”. At the same time, it had the objective to offer to them a social and financial impact, which is a trust on the future, the first job for the young adults’ participant of this program and an increase on their family source of revenues, through salaries. This was...

  2. "We'll turn your water into Coca-Cola"

    NARCIS (Netherlands)

    Vos, de Rosanne; Köhne, Michiel; Roth, Dik

    2018-01-01

    This article discusses land control strategies and practices for development of large-scale oil palm plantations in West Kalimantan, Indonesia. In oil palm and "land grab" literature, much attention is paid to potential contributions of free, prior, and informed consent procedures. However, this

  3. The good, the bad, the Jolly: Taste, image, and the symbolic resistance to the Coca-colonization of Denmark

    DEFF Research Database (Denmark)

    Askegaard, Søren; Csaba, Fabian F.

    1999-01-01

    This inquiry examines the efforts of Denmark's once favoured national cola, Jolly Cola, to resist the advancement of Coca-cola and, to a lesser degree, Pepsi. In moving our looking glass to the struggles of this obscure Danish product, we seek to move the debate on globalization, consumption...... and culture home to our own back yard. From there we offer a refreshing story, drawing on our local narrative tradition and woven together with advertising imagery, about the symbolic resistance to the Coca-colonization....

  4. Treatment of gastric phytobezoars with Coca-Cola® given via oral route: a case report

    Directory of Open Access Journals (Sweden)

    Ertuğrul G

    2012-02-01

    Full Text Available Gökhan Ertuğrul1, Murat Coşkun1, Mahsuni Sevinç1, Fisun Ertuğrul2, Toygar Toydemir31Department of General Surgery, Düzce Atatürk State Hospital, Muncurlu, Düzce, Turkey; 2Department of Anaesthesiology and Reanimation, Düzce Atatürk State Hospital, Muncurlu, Düzce, Turkey; 3Department of General Surgery, İstanbul Surgery Hospital, Nisantasi, İstanbul, TurkeyBackground: A 43-year-old female patient presented with a chief complaint of upper abdominal pain. As her complaints had lasted for 1 month, an upper gastrointestinal system endoscopy was performed and discovered a bezoar in the stomach.Case presentation: The bezoar was quite hard and light green-yellow in color. Pathological examination revealed phytobezoar. The patient was hospitalized and given oral Coca-Cola® Zero for seven days at a dose of 500 mL three times daily.Conclusion: The upper gastrointestinal system endoscopy performed at the end of 7 days showed that the phytobezoar had softened and become smaller. The phytobezoar was broken into pieces with biopsy forceps and washing was applied, so the phytobezoar pieces could pass through the pylorus. The patient was discharged after the procedure without problem.Keywords: gastric phytobezoar, Coca-Cola, upper gastrointestinal system endoscopy

  5. Los cirujanos y la cocaína. Facile est inventis addere

    Directory of Open Access Journals (Sweden)

    Jorge Dagnino Sepúlveda

    2007-08-01

    Full Text Available Este artículo, tercero de una serie sobre el desarrollo de la anestesia local, describe los acontecimientos que siguieron al descubrimiento hecho por Carl Koller en 1884 del uso anestésico de la cocaína hasta la introducción de la procaína por Einhorn. En un lapso de veinte años, varias investigaciones culminaron con la introducción de muchas de las técnicas de anestesia local y regional usadas contemporáneamente: troncular, por infiltración, raquídea y peridural caudal. El escrito toca aspectos tales como la juventud de los innovadores, en su mayoría cirujanos, la toxicidad y el terrible poder de adicción de la cocaína que alcanzó a algunos de ellos, las disputas por la precedencia y la tradición de autoexperimentación.

  6. Measuring the Effectiveness of Sales Promotion Activities on Brand Loyalty: A Study on COCA COLA

    Directory of Open Access Journals (Sweden)

    Uma Shankar Singh

    2017-03-01

    Full Text Available The study is descriptive in nature measuring the effect and relationship in between sales promotion activities and brand loyalty. The study is done on COCA COLA brand in the open market. The research problem observed here as to measure the efficiency of sales promotion and brand loyalty to get the real effectiveness on sales promotion activities. The research objectives formulated are to know the importance of component of sales promotion activities, to know the effect of advertising on sales promotion activities, to realize the importance of brand loyalty on sales promotion activities. A quantitative method was used to accomplish the purpose of the study. A survey instrument developed taking items to measure all variables with five points likert scale. A sample size of 159 (from 210 incorporated in the study having the reliability of 0.851(more than 0.7. The data analyzed using SPSS for descriptive statistics and regression to measure the effect of independent variable on dependent variable. It is recommend that COCA COLA should improve more on its different activities and produce different product and with tasty fast food or build up different production of equipment to expand its business in the whole world’s market .

  7. The Rhetoric of the iconic discourse within the Coca-Cola brand

    Directory of Open Access Journals (Sweden)

    Mărioara VLIONCU

    2013-10-01

    Full Text Available Cet article, tel que son nom de Rhétorique du discours iconique de la marque Coca-Cola l’annonce, a comme thème la structure de la rhétorique des publicités de la marque Coca-Cola. Ces dernières sont représentées, de manière conventionnelle, par deux annexes auxquelles se réfère cette analyse. Ce que ce débat, à caractère sémio-rhétorique, se propose en particulier, c’est de mettre en évidence les liens qui s’établissent entre l’énoncé iconique des réclames de la marque Coca-Cola et les éléments rhétoriques de celui-ci. Les deux composantes (iconique et rhétorique sont évaluées de la perspective d’un discours public, d’un message de nature promotionnelle qui caractérise le marché libre. Cette approche se propose de démontrer les particularités de la rhétorique iconique qui, par le phénomène de l’argumentation discursive, poursuit l’acceptation d’une idée en vertu de raisons pragmatiques ou d’intérêts actionnels. La présente analyse a comme but l’identification des composantes de l’iconicité rhétorique et de la spécificité de celle-ci. L’article trace en ce sens les contours d’une stratégie analytique peu commune ; son objectif consiste dans la présentation d’une liaison pouvant être faite entre l’image et les valeurs rhétoriquesde celle-ci. Le thème de l’analyse est basé sur une dimension théorique qui renvoie à la manière dont les publicités Coca-Cola donnent naissance à un discours qui peut être étudié à partir de catégories rhétoriques telles : ethos, mythos, pathos etc. La seconde partie de l’article représente une analyse de la narrativité iconique et met en évidence la caractéristique rhétorique des images de la marque soumise à l’étude. Cette recherche se veut une proposition d’ordre sémio-linguistique et rhétorique, une évaluation iconique des signes dans le cadre des publicités en général et des publicités de la marque Coca

  8. Cuando ya no se puede tomar trago ni chacchar coca. When alcohol can no longer be drunk or coca leaves chewed. the case of the “protestants” in the Peruvian central Andes

    Directory of Open Access Journals (Sweden)

    Caroline Magny

    2009-12-01

    Full Text Available Desde hace mucho tiempo el alcohol y la coca ocupan un lugar central en las comunidades andinas. Hasta ahora en el distrito de Churcampa (Huancavelica, Perú, los católicos, mayoritarios, siguen explicando al visitante lo siguiente: “acá no se puede hacer nada sin trago ni coca”. No obstante, durante las ultimas décadas, muchas personas en este distrito – así como en muchos otros distritos de los Andes peruanos – se han convertido y siguen convirtiéndose al “protestantismo” (termino genérico usado por los católicos para referirse en forma general a las Iglesias evangélicas. Esta conversión implica, entre otras cosas, dejar completamente de masticar hojas de coca y de beber cualquier tipo de bebidas alcohólicas. En esta exposición proponemos analizar hasta qué punto y bajo qué modalidades estas restricciones alimenticias afectan a los conversos (quienes siguen siendo minoritarios en el distrito en su vida social cotidiana.Alcohol and coca have played a central role in Andean communities for many centuries. Nowadays, in the district of Churcampa (Huancavelica, Peru, the Catholic people, who are the majority, still explain to visitors that “here you can’t do anything without trago [alcohol] and coca”. Yet, over the past decades, many men and women in this district - as well as in many other districts of the Peruvian Andes - have been converting to “Protestantism” (a generic term used by Catholics to refer to the Evangelical Churches. This conversion implies, among other things, completely giving up chewing of coca leaves and drinking of any type of alcoholic drink. The aim of this article is to analyze to what extent and how these restrictions in the dietary habits affect converted people in their everyday social life.alcohol, coca leaves, religion, conversion, evangelic Churches, Peru

  9. Unique proline-benzoquinone pigment from the colored nectar of "bird's Coca cola tree" functions in bird attractions.

    Science.gov (United States)

    Luo, Shi-Hong; Liu, Yan; Hua, Juan; Niu, Xue-Mei; Jing, Shu-Xi; Zhao, Xu; Schneider, Bernd; Gershenzon, Jonathan; Li, Sheng-Hong

    2012-08-17

    The major pigment responsible for the dark brown nectar of the "bird's Coca cola tree", Leucosceptrum canum (Labiatae), was isolated and identified as a unique symmetric proline-quinone conjugate, 2,5-di-(N-(-)-prolyl)-para-benzoquinone (DPBQ). Behavioral experiments with both isolated and synthetic authentic samples indicated that DPBQ functions mainly as a color attractant to bird pollinators.

  10. Klaaspudelist loobumine vähendab Coca-Cola brändi eeliseid / Eda-Liis Kann

    Index Scriptorium Estoniae

    Kann, Eda-Liis, 1979-

    2005-01-01

    BRAND sense uuringu kohaselt, milles uuriti pakendi mõju brändilojaalusele, eelistab enam kui 60% Ameerika ja Suurbritannia tarbijaist juua kokakoolat klaaspudelist. Majanduslikel põhjustel on Coca-Cola Company aga viimased kümme aastat tegelenud klaaspudelite poelettidelt ära korjamisega. Diagramm

  11. A system dynamics approach to the study of Colombian coca cultivation and the counter-intuitive consequence of law enforcement.

    Science.gov (United States)

    Jaén, Sebastian; Dyner, Isaac

    2014-03-01

    A large-scale expansion of the Colombian coca cultivation is one of the most revealing signs of a structural change in the illegal cocaine market in the Andean region. From being a modest and domestic production, in the space of five years Colombian coca cultivation supplied a competitive market, capable of substituting almost completely the foreign sources of supply. The purpose of this work is to explore the role and potential of system dynamics (SD) as a modeling methodology to better understand the consequences of drug policy. As a case study, this work tests the hypothesis that the outbreak of Colombian coca cultivations is a consequence of the take down of large cartels, leading to the surge of small drug-trafficking firms called "cartelitos." Using an SD model, and elements from the economic theory of the criminal firm, our work shows how the formation of these small firms might significantly contribute to the configuring of a more competitive domestic coca industry (and hence to a more efficient crime industry). We conclude that SD seems an appropriate dynamic modeling-based approach to address policy issues regarding drug markets. The methodology takes into account the dynamic nature of drug markets and their multi-dimensional responses to policy interventions. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Estudio in vitro sobre los efectos de la cocaína sobre los tejidos duros del diente In vitro study on the effects of cocaine on the hard tissues of the tooth

    Directory of Open Access Journals (Sweden)

    Eduvigis Solórzano Navarro

    2008-12-01

    Full Text Available El uso de los derivados de la cocaína es un problema de salud pública en continuo crecimiento. Estas drogas son frecuentemente frotadas sobre la mucosa gingival, pero sus efectos son poco conocidos y de difícil diagnóstico. Con este trabajo se pretende demostrar in vitro, que la aplicación por frotación de la cocaína sobre la superficie dentaria produce erosión del esmalte. Se seleccionaron 30 dientes sanos, distribuidos aleatoriamente en 3 grupos, a los cuales se frotó sobre la superficie vestibular clorhidrato de cocaína, basuco y limón (grupo control respectivamente, durante 40 semanas. Las lesiones más características observadas fueron fractura y pérdida de sustancia dura, demostrando así que la aplicación tópica y continua de drogas en cavidad bucal produce lesiones en los tejidos duros del diente.The use of cocaine derivatives is an increasingly growing public health problem. These drugs are frequently rubbed on the gingival mucosa, but their efffects are little known and difficult to be diagnosed. This paper pretends to prove in vitro that the rubbing of cocaine on the dental surface produces enamel erosion. 30 healthy teeth were selected and distributed at random into 3 groups that were rubbed cocaine hydrochloride, bazuko and lemon (control group on the vestibular surface, respectively, during 40 weeks. The most observed characteristic lesions were fracture and loss of the dental hard substance, which showed that the topical and continual application of drugs on the oral cavity causes lesions in the hard tissues of the tooth.

  13. Alterações neuropsicológicas em dependentes de cocaína/crack internados: dados preliminares Neuropsychological impairments in crack cocaine-dependent inpatients: preliminary findings

    Directory of Open Access Journals (Sweden)

    Paulo J Cunha

    2004-06-01

    Full Text Available OBJETIVO: Embora o uso de cocaína seja um problema significativo de saúde pública, há uma relativa escassez de dados científicos sobre as conseqüências neurocognitivas decorrentes da exposição à substância. MÉTODOS: Esse estudo avaliou a associação entre dependência de cocaína e crack e desempenho cognitivo. Uma ampla bateria de testes neuropsicológicos foi aplicada a 15 dependentes de cocaína, em abstinência por duas semanas, em tratamento em regime de internação, e em 15 sujeitos controles, não usuários de drogas, pareados por idade, sexo, escolaridade, nível sócio-econômico, lateralidade e QI. RESULTADOS: Os resultados preliminares mostraram significação estatística (pOBJECTIVE: Although cocaine use is a significant public health problem, there is relative paucity of scientific data on long-term neurocognitive consequences of the exposure to the substance. METHODS: This study examined the association between crack cocaine dependence and neuropsychological performance. An extended battery of neuropsychological tests was administered to 15 abstinent cocaine abusers, inpatients in abstinence for two weeks, and 15 non-drug-using control subjects matched for age, gender, education, socio-economic status, handedness and IQ. RESULTS: The preliminary findings showed statistical significance (p<0,05 on differences of performance in attention, verbal fluency, verbal memory, visual memory, learning ability and executive functions. CONCLUSIONS: These results represent evidences that cocaine abuse is associated with decrements in cognitive functioning, similar to cognitive disorders associated to prefrontal and temporal brain impairments. Knowledge of specific cognitive deficits in cocaine abusers may be useful for designing more effective substance abuse prevention and treatment programs.

  14. 78 FR 46369 - Importer of Controlled Substances; Notice of Application; Research Triangle Institute

    Science.gov (United States)

    2013-07-31

    ... Anileridine (9020) II Bezitramide (9800) II Carfentanil (9743) II Coca Leaves (9040) II Cocaine (9041) II... controlled substances listed in schedule I or II, which fall under the authority of section 1002(a)(2)(B) of...

  15. A laboratory approach to the control of cocaine in Bolivia.

    Science.gov (United States)

    Morales-Vaca, M

    1984-01-01

    Of the 4,196 samples of drugs seized and analysed at the Toxicology Laboratory of the National Bureau for the Control of Dangerous Substances during the period 1975-1982, 3,768 samples (89.8 per cent) contained coca paste, cocaine hydrochloride or related substances. Most of the samples analysed contained coca paste and came from La Paz, Santa Cruz and Cochabamba. With a slight exception in 1980, the number of samples increased steadily over an eight-year period. The increase in the number of seizures of cocaine-related substances was a result of the growth in the illicit production of these substances, which began to assume larger dimensions in 1976. In many areas, coca-paste and cocaine-related problems are growing out of all proportion. The smoking of cigarettes that contain a mixture of tobacco and coca paste, popularly known as pitillos, is the most common form of drug abuse.

  16. Arteriopatía periférica crónica inducida por cocaína

    Directory of Open Access Journals (Sweden)

    Sonia Pankl

    2012-02-01

    Full Text Available La trombosis periférica aguda inducida por cocaína ha sido descripta en la literatura, siendo una complicación poco común. Si bien existen comunicaciones que reflejan los efectos crónicos de la cocaína sobre el sistema arterial periférico, no hay casos publicados de tal complicación en ausencia de otros factores de riesgo. Se presenta el caso de una mujer de 22 años de edad con antecedentes de consumo de cocaína intranasal de 3 gramos por semana durante un año, que consultó por claudicación intermitente a los 200 metros asociada a dolor y parestesias en miembro inferior izquierdo de 2 meses de evolución. El ecodoppler arterial evidenció una estenosis mayor del 70% en la arteria femoral superficial izquierda. Se realizaron estudios complementarios descartando otras etiologías probables. Se inició tratamiento con ácido acetilsalicílico, cilostazol y ejercicio reglado, asociado a terapia de apoyo para mantenimiento del cese del consumo de cocaína, con buena respuesta. Se destaca la importancia de la difusión de información a los pacientes, dado que la mayoría de la población desconoce las complicaciones cardiovasculares de dicha adicción. Es indispensable indagar sobre el consumo de cocaína en pacientes jóvenes con arteriopatía sin factores de riesgo aparentes.

  17. Fluorescent nanoparticles present in Coca-Cola and Pepsi-Cola: physiochemical properties, cytotoxicity, biodistribution and digestion studies.

    Science.gov (United States)

    Li, Shen; Jiang, Chengkun; Wang, Haitao; Cong, Shuang; Tan, Mingqian

    2018-02-01

    Foodborne nanoparticles (NPs) have drawn great attention due to human health concerns. This study reports the detection of the presence of fluorescent NPs, about 5 nm, in two of the most popular beverages, Coca-Cola (Coke) and Pepsi-Cola (Pepsi). The NPs contain H, C and O, three elements with a tunable emission and with a quantum yield of 3.3 and 4.3% for Coke and Pepsi, respectively. The presence of sp 3 -hybridized carbon atoms of alcohols and ethers bonds was confirmed by NMR analysis. The NPs can be taken up by living cells and accumulate within cell membrane and cytoplasm. Evaluation of the acute toxicity of the NPs revealed that the BALB/c mice appeared healthy after administration of a single dose of 2 g kg -1 body weight. Analysis of glutamate pyruvate transaminase (GPT), glutamic oxaloacetic transaminase (GOT), urea and creatinine showed that there were statistically, but not biologically, significant differences in some of these biochemical parameters between the test and control groups. No obvious organ damage or apparent histopathological abnormality was observed in the tested mice. The biodistribution study in major organs indicated that the NPs were easily accumulated in the digestive tract, and they were able to cross the blood-brain barrier and dispersed in the brain. In vitro digestion of the NPs showed a significant fluorescence quenching of the NPs. This work represents the first report of foodborne fluorescent NPs present in Coke and Pepsi, and provides valuable insights into physicochemical properties of these NPs and their toxicity characteristics both in vitro and in vivo.

  18. Treatment of gastric phytobezoars with Coca-Cola given via oral route: a case report.

    Science.gov (United States)

    Ertuğrul, Gökhan; Coşkun, Murat; Sevinç, Mahsuni; Ertuğrul, Fisun; Toydemir, Toygar

    2012-01-01

    A 43-year-old female patient presented with a chief complaint of upper abdominal pain. As her complaints had lasted for 1 month, an upper gastrointestinal system endoscopy was performed and discovered a bezoar in the stomach. The bezoar was quite hard and light green-yellow in color. Pathological examination revealed phytobezoar. The patient was hospitalized and given oral Coca-Cola(®) Zero for seven days at a dose of 500 mL three times daily. The upper gastrointestinal system endoscopy performed at the end of 7 days showed that the phytobezoar had softened and become smaller. The phytobezoar was broken into pieces with biopsy forceps and washing was applied, so the phytobezoar pieces could pass through the pylorus. The patient was discharged after the procedure without problem.

  19. Fluorescent carbon nanodots facilely extracted from Coca Cola for temperature sensing

    Science.gov (United States)

    Li, Feiming; Chen, Qiaoling; Cai, Zhixiong; Lin, Fangyuan; Xu, Wei; Wang, Yiru; Chen, Xi

    2017-12-01

    A novel method for the fabrication of carbon nanodots (CDs) is introduced: extracting CDs from the well-known soft drink Coca Cola via dialysis. The obtained CDs are of good monodispersity with a narrow size distribution (average diameter of 3.0 nm), good biocompatibility, high solubility (about 180 mg ml-1) and stable fluorescence even at a high salt concentration. Furthermore, they are sensitive to the temperature change with a linear relationship between the fluorescence intensity and temperature from 5 °C-95 °C. The CDs have been applied in high stable temperature sensing. This protocol is quite simple, green, cost-effective and technologically simple, which might be used for a range of applications including sensing, catalysts, drug and gene delivery, and so on.

  20. Treatment of gastric phytobezoars with Coca-Cola® given via oral route: a case report

    Science.gov (United States)

    Ertuğrul, Gökhan; Coşkun, Murat; Sevinç, Mahsuni; Ertuğrul, Fisun; Toydemir, Toygar

    2012-01-01

    Background A 43-year-old female patient presented with a chief complaint of upper abdominal pain. As her complaints had lasted for 1 month, an upper gastrointestinal system endoscopy was performed and discovered a bezoar in the stomach. Case presentation The bezoar was quite hard and light green-yellow in color. Pathological examination revealed phytobezoar. The patient was hospitalized and given oral Coca-Cola® Zero for seven days at a dose of 500 mL three times daily. Conclusion The upper gastrointestinal system endoscopy performed at the end of 7 days showed that the phytobezoar had softened and become smaller. The phytobezoar was broken into pieces with biopsy forceps and washing was applied, so the phytobezoar pieces could pass through the pylorus. The patient was discharged after the procedure without problem. PMID:22393302

  1. Gastric phytobezoars may be treated by nasogastric Coca-Cola lavage.

    Science.gov (United States)

    Ladas, Spiros D; Triantafyllou, Konstantinos; Tzathas, Charalabos; Tassios, Pericles; Rokkas, Theodore; Raptis, Sotirios A

    2002-07-01

    Large gastric phytobezoars may occur in patients with gastric dysmotility disorders. Treatment options include dissolution with enzymes, endoscopic fragmentation with removal or aspiration, and surgery. We report our experience with nasogastric cola lavage therapy. Over an 8-year period, five consecutive patients were referred to our unit for endoscopic treatment of large gastric phytobezoars. They included one patient with lobectomy for lung cancer and four patients with diabetic gastroparesis. An initial attempt of endoscopic fragmentation and removal was unsuccessful. Patients were treated with 3 l of Coca-Cola nasogastric lavage over 12 h. Nasogastric lavage was very well tolerated by the patients. Complete phytobezoar dissolution was achieved in one session in all cases. There were no procedure-related complications. The dissolution of large gastric phytobezoars with cola nasogastric lavage is a safe, rapid and effective method. Patients may be treated in the medical ward, avoiding therapeutic endoscopy or surgery.

  2. Coca-Cola : stratégie de l’immanence et narrative

    OpenAIRE

    Alen, Fanny

    2017-01-01

    L’essentiel de ce mémoire consiste à se pencher sur les deux stratégies mises en place par la firme The Coca-Cola Company, au travers ses annonces télévisées. Le leader mondial des sodas est devenu une multinationale qui ne cesse d’éblouir ses consommateurs au travers ses spots publicitaires. Comment y parvient-il ? L’objectif de cette recherche a été de parvenir à découvrir la recette magique, non pas du célèbre Coke, mais du mélange entre narration et immanence. Tour à tour, ...

  3. Enamel softening with Coca-Cola and rehardening with milk or saliva.

    Science.gov (United States)

    Gedalia, I; Dakuar, A; Shapira, L; Lewinstein, I; Goultschin, J; Rahamim, E

    1991-06-01

    Rehardening effects by cow's milk and by secreted saliva were investigated, in situ, following softening of human enamel with an acidic beverage (Coca-Cola). Volunteers wearing orthodontic removable appliances participated in the study. The intra-oral test was chosen for measuring microhardness of enamel slabs inserted into the dental appliance. The softening and the rehardening degrees were defined as the alterations between initial- and experimental-microhardness value at the enamel surface. In addition, SEM photos were prepared from the initial and experimental stages. Exposure of enamel slabs to the acidic beverage during 1 hour had a softening effect as expressed by the hardness decrease and visualized by the SEM photo. Rehardening effects following milk or saliva exposures respectively were evident, presumably due to deposited organic and mineral material on the enamel surface.

  4. Órdenes subsidiarios. Coca, esmeraldas: la guerra y la paz.

    Directory of Open Access Journals (Sweden)

    Francisco Gutiérrez

    2008-06-01

    Full Text Available This article explains how the emerald and coca economies are ingrained in the Colombian conflict. We interpret the mechanisms that generate conflict or peace, order or disorder. Our analysis is supported on Richard Snyder’s model which offers analytical elements to understand how violent reaction and raw products exports correlate with each other. We conclude that the described economies have had very violent courses but have also opened up specific paths to peace, of which the prerequisites are the denial of democratic freedom, privatization of public economies, and the endorsement and strengthening of illegal or semi-legal actors. We also make a critical exam of Snyder’s model.

  5. Ocular injuries from exploding glass-bottled Coca-Cola® drinks in Port Harcourt, Nigeria.

    Science.gov (United States)

    Pedro-Egbe, Chinyere Nnenne; Ejimadu, Chibuike Sydney; Nwachukwu, Henrietta

    2011-01-01

    Eye injuries and subsequent loss of vision from the glass and caps of exploding pressurized bottled drinks have been well reported, and as a result most developed countries now use mainly plastic bottles. In Nigeria, however, most drinks are still sold in glass bottles and ocular injuries from this source are therefore not uncommon. To retrospectively analyze ocular injuries resulting from exploding glass-bottled Coca-Cola® and propose ways of eliminating such injuries in future. Eye Clinic, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria. The medical records of all cases of ocular injury that presented at the Eye Clinic of the University of Port Harcourt Teaching Hospital over a 5-year period (January 2006 to December 2010) were retrieved and relevant data including age, sex, occupation, events surrounding bottle explosion, and type of ocular injury sustained were extracted. A total of 426 cases of ocular injuries was seen during the period under review. There were 335 (78.6%) males and 91 (21.4%) females. Six patients had ocular injury from exploding glass-bottled Coca-Cola®, giving an incidence of 1.4%. The presenting visual acuities (VA) were light perception (2 cases), counting fingers (2 cases), and 1 VA of 6/24 and 1 VA of 6/12. There were 4 (66.7%) cases of corneoscleral laceration with uveal prolapse and 1 case of total hyphema. Because pressurized glass-bottles can explode with normal handling, legislation to ban the use of glass containers for bottling carbonated drinks will go a long way to reducing ocular morbidity from this source. Plastic bottles should be introduced as an alternative.

  6. Ocular injuries from exploding glass-bottled Coca-Cola® drinks in Port Harcourt, Nigeria

    Directory of Open Access Journals (Sweden)

    Pedro-Egbe CN

    2011-05-01

    Full Text Available Chinyere Nnenne Pedro-Egbe, Chibuike Sydney Ejimadu, Henrietta NwachukwuDepartment of Ophthalmology, University of Port Harcourt Teaching Hospital, Port Harcourt, NigeriaBackground: Eye injuries and subsequent loss of vision from the glass and caps of exploding pressurized bottled drinks have been well reported, and as a result most developed countries now use mainly plastic bottles. In Nigeria, however, most drinks are still sold in glass bottles and ocular injuries from this source are therefore not uncommon.Aim: To retrospectively analyze ocular injuries resulting from exploding glass-bottled Coca-Cola® and propose ways of eliminating such injuries in future.Setting: Eye Clinic, University of Port Harcourt Teaching Hospital, Port Harcourt, Nigeria.Materials and methods: The medical records of all cases of ocular injury that presented at the Eye Clinic of the University of Port Harcourt Teaching Hospital over a 5-year period (January 2006 to December 2010 were retrieved and relevant data including age, sex, occupation, events surrounding bottle explosion, and type of ocular injury sustained were extracted.Results: A total of 426 cases of ocular injuries was seen during the period under review. There were 335 (78.6% males and 91 (21.4% females. Six patients had ocular injury from exploding glass-bottled Coca-Cola®, giving an incidence of 1.4%. The presenting visual acuities (VA were light perception (2 cases, counting fingers (2 cases, and 1 VA of 6/24 and 1 VA of 6/12. There were 4 (66.7% cases of corneoscleral laceration with uveal prolapse and 1 case of total hyphema.Conclusion: Because pressurized glass-bottles can explode with normal handling, legislation to ban the use of glass containers for bottling carbonated drinks will go a long way to reducing ocular morbidity from this source. Plastic bottles should be introduced as an alternative.Keywords: ocular injuries, exploding glass-bottled drink

  7. DESDE AMBROSETTI HASTA RABEY, SOBRE LA COCA Y EL COQUEO EN ARGENTINA

    Directory of Open Access Journals (Sweden)

    Akira Igaki

    2010-01-01

    Full Text Available La hoja de coca, apreciada entre los pueblos indígenas desde sus primeros contactos y difundida por ellos hacia otros lugares durante milenios, entró a los complejos procesos conflictivos -tanto interculturales como internacionales- de estigmatización y marginalización desde el período colonial hasta el día de hoy. Argentina se encuentra dentro de estos procesos pues la coca es comúnmente usada en áreas andinas del norte del país. Este trabajo presenta a dos científicos sociales argentinos -Juan Bautista Ambrosetti y Mario Rabey- de dos épocas que no solamente separan por casi cien años la publicación de sus estudios sobre los usos de la hoja sino también otorgan diferentes significados en el objeto y objetivo del estudio. Mientras Ambrosetti representa y legitima con su lenguaje la hegemonía que estigmatiza la práctica cultural no europea, como lo son dichos usos, Rabey los reivindica como parte de la diversidad cultural entendida como diferencia cultural discriminada, con una postura crítica a la hegemonía idiosincrásica nacional. A través de la comparación entre ellos, este trabajo relata el cambio en la mirada antropológica y su posición como producto de un complejo desenvolvimiento de relaciones entre dicha diferencia y su significado en la ciencia y política.

  8. Brain injury markers (S100B and NSE in chronic cocaine dependents Marcadores de lesão cerebral (S100B e NSE em dependentes crônicos de cocaína

    Directory of Open Access Journals (Sweden)

    Felix Henrique Paim Kessler

    2007-06-01

    Full Text Available OBJECTIVE: Studies have shown signs of brain damage caused by different mechanisms in cocaine users. The serum neuron specific enolase and S100B protein are considered specific biochemical markers of neuronal and glial cell injury. This study aimed at comparing blood levels of S100B and NSE in chronic cocaine users and in volunteers who did not use cocaine or other illicit drugs. METHOD: Twenty subjects dependent on cocaine but not on alcohol or marijuana, and 20 non-substance using controls were recruited. Subjects were selected by consecutive and non-probabilistic sampling. Neuron specific enolase and S100B levels were determined by luminescence assay. RESULTS: Cocaine users had significantly higher scores than controls in all psychiatric dimensions of the SCL-90 and had cognitive deficits in the subtest cubes of WAIS and the word span. Mean serum S100B level was 0.09 ± 0.04 µg/l among cocaine users and 0.08 ± 0.04 µg/l among controls. Mean serum neuron specific enolase level was 9.7 ± 3.5 ng/l among cocaine users and 8.3 ± 2.6 ng/l among controls. CONCLUSIONS: In this first study using these specific brain damage markers in cocaine users, serum levels of S100B and neuron specific enolase were not statistically different between cocaine dependent subjects and controls.OBJETIVO: Estudos têm demonstrado sinais de lesão cerebral causadas por diferentes mecanismos em usuários de cocaína. A enolase sérica neurônio-específica e a proteína S100B são consideradas marcadores bioquímicos específicos de lesão neuronal e glial. Este estudo objetivou comparar os níveis sangüíneos de S100B e enolase sérica neurônio-específica em usuários crônicos de cocaína e em voluntários que não usam cocaína ou outras drogas ilícitas. MÉTODO: Vinte sujeitos dependentes de cocaína, mas não dependentes de álcool, maconha ou outra droga, e 20 sujeitos controles não usuários de drogas foram recrutados. Os sujeitos foram selecionados por

  9. Komunikační strategie nové plastové láhve společnosti Coca-Cola.

    OpenAIRE

    Němcová, Klára

    2009-01-01

    The thesis relates to theorethical principles of marketing and commercial communications. The application part of the thesis relates to a concept of communication strategy of The Coca-Cola Company's new plastic bottle

  10. Podnikatelské strategie pro čínský trh - příklad společnosti Coca-Cola, HBC

    OpenAIRE

    Kyselová, Karolina

    2011-01-01

    This thesis deals with the business strategy in the Chinese market, which is introduced a concrete example of the business strategy of Coca-Cola. According the breadth of the topic there is not included the overall business strategy of mentioned company, but corporate social responsibility, which is the third pillar of the strategy. The aim is to compare by values of social responsibility and setting the Coca-Cola's current situation on the Chinese market and local governments attitude to the...

  11. Pengaruh Kesehatan Dan Keselamatan Kerja Terhadap Kinerja Karyawan Pada PT.Coca-Cola Amatil Indonesia (CCAI) Unit Medan Dengan Motivasi Sebagai Variabel Intervening

    OpenAIRE

    Harahap, Debbyanzah Fahmi

    2016-01-01

    The purpose of this study was to determine the effect of the Health and Safety of the employee's performance at Coca-Cola Amatil Indonesia (CCAI) at Medan. The analytical method used is descriptive analysis and path analysis. The study population consisted of 174 employees at Coca-Cola Amatil Indonesia (CCAI) at Medan. The sample in this study using simple random sampling, totaling 64 employees. collection of primary data using questionnaires and secondary data collection using case studie...

  12. Aspectos Farmacológicos y Socioculturales del consumo de hoja de coca en indígenas Koguis respecto al consumo de cocaína en ambientes urbanos

    Directory of Open Access Journals (Sweden)

    Katiuska Vera Zambrano

    2002-07-01

    Full Text Available La investigación compara los aspectos farmacológicos y socioculturales del consumo de la hoja de coca en indígenas Kogui de la Sierra Nevadade Santa Marta en Colombia frente a los aspectos farmacológicos y socioculturales del  consumo de cocaína en los ambientes urbanos, relacionados con los conceptos de tolerancia y dependencia a sustancias psicoactivas. Los resultados aportan al desarrollo  y diseño de programas de prevención, tratamiento y reducción de riesgo y daño en fármaco dependencia, al igual que sugiere la inclusión de aspectos relevantes en futuras políticas sociales de prevención en drogas.

  13. Anormalidades de fluxo sangüíneo cerebral em indivíduos dependentes de cocaína Cerebral blood flow abnormalities in cocaine dependent subjects

    Directory of Open Access Journals (Sweden)

    Sergio Nicastri

    2000-06-01

    Full Text Available INTRODUÇÃO: Nos últimos anos, tem havido relatos de anormalidades do fluxo sanguíneo cerebral em indivíduos com o abuso de cocaína, detectadas por meio de tomografia computadorizada por emissão de fóton único (SPECT. Esse padrão anormal de perfusão cerebral tem sido associado a prejuízos cognitivos mas não a alterações observáveis por meio de exames de neuroimagem estrutural. Um problema envolvendo a maioria dos trabalhos publicados sobre esse tema é a inclusão de um grande número de usuários de heroína nas amostras estudadas. Essa outra droga também parece afetar o padrão de perfusão cerebral, particularmente durante estados de abstinência. MÉTODOS: Quatorze pacientes dependentes de cocaína (nenhum com uso de opióides e 14 voluntários normais (grupo controle foram submetidos a exames de SPECT com dímero de etil-cisteína marcado com tecnécio-99m. A análise dos exames de SPECT foi realizada por meio de análise visual qualitativa das imagens obtidas (procedimento padrão na prática clínica, realizada por um radiologista não informado sobre o diagnóstico dos indivíduos avaliados. RESULTADOS: A análise visual revelou um padrão sugestivo de irregularidades do fluxo sangüíneo cerebral em nove pacientes, mas em apenas dois controles (p = 0,018; teste exato de Fisher bicaudal. CONCLUSÕES: Anormalidades de circulação cerebral podem ter relação com prejuízos cognitivos relatados em populações de dependentes de cocaína. Embora déficits de perfusão cerebral associados ao uso de cocaína possam ser irreversíveis, têm surgido relatos na literatura de tratamentos para essas anormalidades de fluxo sangüíneo. Alterações de fluxo sangüíneo cerebral associadas à dependência de cocaína ocorrem mesmo na ausência de abuso ou dependência de opióides.INTRODUCTION: In the last years, there have been reports of abnormalities in brain blood flow of cocaine abusers, detected by single photon computed

  14. Impact of emotional stability and attitude on consumption decisions under risk: the Coca-Cola crisis in Belgium.

    Science.gov (United States)

    Verbeke, Wim; Van Kenhove, Patrick

    2002-01-01

    This article focuses on consumer reactions during and after the Coca-Cola crisis of June 1999 in Belgium. The research tests for associations between the personality trait "emotional stability," attitude toward the brand, and self-reported behavior. Cross-sectional data are collected from a sample of Coca-Cola drinkers between 19 and 22 years old. The data are analyzed through the specification and estimation of a structural equation model and ANOVA. A direct and positive effect of attitude toward the brand on the behavioral response is found. No direct effect of emotional stability on behavior is revealed. However, indirect effects of personality mediated by attitude are discovered. Further, emotional stability is found to correlate negatively with importance attached to information during the crisis. Fast and transparent communication with specific attention to lower emotional stability groups, as well as the inclusion of personality and attitude measurements in future health and food safety studies, are recommended.

  15. Sangue e Coca-Cola: a carnavalização e a literatura pop de Roberto Drummond

    Directory of Open Access Journals (Sweden)

    Ernest Bowes

    2015-08-01

    Full Text Available Este estudo se propõe à reflexão sobre as obras de Roberto Drummond, mais especificamente Sangue de Coca-Cola – romance que integra o ciclo Coca-Cola do autor. A pesquisa se propõe a demonstrar que a arte pop não é estática e que se materializa através da interação com outras linguagens e com a cultura. Assim, o trânsito entre distintos campos discursivos como a Filosofia, Sociologia e a Teoria da Literatura apresentou-se, então, como a estratégia mais apropriada para discutir a questão.

  16. Asociación de otras drogas de abuso en la intoxicación por cocaína

    OpenAIRE

    JL Echarte Pazos; A Supervía Caparrós; C Clemente Rodríguez; ML Iglesias Lepine; N León Bertrán; V Labordeta de la Cal; I Puente Palacios; G Maldonado Duran; E Skaf Peters; A Aguirre Tejedo

    2011-01-01

    El objetivo del presente trabajo ha sido llevar a cabo un análisis de las urgencias atendidas en un hospital urbano de tercer nivel que se han relacionado con el consumo de cocaína. Para ello se ha realizado un estudio retrospectivo, con exclusión del área de pediatría y ginecología, durante los años 2005 y 2006. Se revisaron todas las asistencias clínicas que consultaron por intoxicación por cocaína. Los datos fueron analizados con el paquete estadístico SPSS 15.0 para windows. Durante el pe...

  17. Análise toxicológica da cocaína e dos seus metabolitos em contexto forense

    OpenAIRE

    Quental, Ana Raquel de Pinho Sousa

    2015-01-01

    Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas Apesar do declínio no consumo de cocaína observado nas últimas décadas, esta continua a ser uma das drogas ilícitas mais consumidas no mundo. A cocaína possui múltiplas ações centrais e periféricas, sendo um potente estimulante do sistema nervoso central e também um anestésico local com propriedades vasoconstritoras. O seu consu...

  18. Los efectos globo en los cultivos de coca en la Región Andina (1990-2009

    Directory of Open Access Journals (Sweden)

    Leonardo Raffo López

    2016-01-01

    Full Text Available El objetivo de este artículo es poner a prueba estadísticamente la presencia de efectos globo en los cultivos de coca en el territorio geográfico correspondiente a los principales países productores en la región andina (Colombia, Perú y Bolivia durante el periodo 1990-2009. La metodología empírica se centra en la especificación y estimación de un modelo de ecuaciones simultáneas utilizando el método SUR, el cual permite explicar el comportamiento de las hectáreas cultivadas con coca en función de un conjunto de determinantes. Se concluye que hay evidencia empírica a favor de la presencia de efectos globo en la región andina a lo largo del periodo estudiado.

  19. Intoxicação espontânea e experimental por folhas e frutos de Erythroxylum deciduum (cocão em ovinos no Estado de Santa Catarina

    Directory of Open Access Journals (Sweden)

    V. Borelli

    2011-03-01

    Full Text Available Descreve-se uma enfermidade em ovinos de ocorrência sazonal, caracterizada por manifestações nervosas e morte rápida, nos municípios de Rancho Queimado e Ponte Alta do Sul, no estado de Santa Catarina. A doença foi reproduzida experimentalmente em ovinos com a administração de folhas de Erythroxylum deciduum coletados durante o verão, com doses letais a partir de 10g/kg de peso vivo. Em um único experimento com os frutos a dose de 15g/kg foi letal. O início da manifestação dos sinais clínicos, ocorreu entre 0 e 2 horas após a administração das folhas ou dos frutos e a evolução da doença foi de 10 minutos a 18 horas. Doses de até 20g/kg de folhas coletadas no período de inverno, produziram alterações clínicas discretas em dois ovinos. Os sinais clínicos foram depressão, sonolência e, quando os animais eram movimentados, incoordenação motora, desequilíbrio, quedas, dificuldade para se levantar e estação com os membros abertos. Também foi observado: salivação intensa, regurgitação, bruxismo, aumento das frequências cardíaca e respiratória. Os sinais clínicos se agravavam quando os animais eram movimentados e geralmente resultavam em morte. Os animais que morreram pelas intoxicações espontânea e experimental, não tinham alterações macroscópicas e microscópicas significativas. O corte das árvores de E. deciduum faz com que o tronco rebrote, favorecendo a ingestão da planta pelos ovinos. Este fato e a disponibilidade de frutos maduros que caem ao chão podem ser responsabilizados pela doença de ovinos com sinais nervosos e ausência de lesões macroscópicas e microscópicas, que ocorrem nos meses de verão, no Estado de Santa Catarina.

  20. Analisis Brand Association CocaCola dalam Pembentukan Brand Image Konsumen (Studi Kasus Pada Mahasiswa Universitas Sumatera Utara)

    OpenAIRE

    Silitonga, Lewildy V

    2012-01-01

    Image of a product can not be separated from the view or perception given by the consumers (respondents), whether or not a product consumers who rate it as users and customers concerned. The aim of the research was to know and analyze the brand association that forms CocaCola brand image in the minds of consumers in the North Sumatra University students. This research was descriptive.. It used descriptive analytic method, statistical method, that is, the validity and reliability test with ...

  1. Obstructive Bezoars of the Small Bowel Treated with Coca-Cola Zero through a Long Intestinal Tube and Endoscopic Manipulation.

    Science.gov (United States)

    Endo, Kei; Kakisaka, Keisuke; Suzuki, Yuji; Matsumoto, Takayuki; Takikawa, Yasuhiro

    2017-11-15

    An 82-year-old Japanese man visited our hospital with abdominal fullness accompanied by lower abdominal pain. He presented with small bowel obstruction due to multiple diospyrobezoars. The bezoars were successfully removed without any surgical intervention by the administration of Coca-Cola Zero through a long intestinal tube and subsequent endoscopic manipulation. Such a combination may be the treatment of choice for small bowel obstruction due to bezoars.

  2. The brand images of Coca-Cola and Pepsi and buying motives of cola consumers: a consumer research study

    OpenAIRE

    Yılmaz, Emre

    1997-01-01

    Ankara : The Department of Management and Graduate School of Business Administration of Bilkent University, 1997. Thesis (Master's) -- Bilkent University, 1997. Includes bibliographical references leaves 54-55 Cola is one of the heavily consumed products all over the world by almost every individual. Today there are two main competitors in the world to convince consumers to consume their brand; Coca-Cola and Pepsi. Both companies give a big importance to understand their con...

  3. Analisis Faktor-Faktor yang Mempengaruhi Loyalitas Konsumen Terhadap Merek Coca-cola (Studi pada Restoran Sop Saudara Medan)

    OpenAIRE

    Puspasari, Indriyani

    2015-01-01

    This study aims to determine the factors that influence consumer loyalty to the brand coca - cola at Soup Brothers Restaurant Medan . Where consumer loyalty is a manifestation and continuation of customer satisfaction in using the facilities and services provided by the company . Loyalty is bbukti consumers who always want to be the consumer , who has the strength and positive attitude over the company . While the brand is a name , term , symbol , or design , or a combination of these things ...

  4. Projekt managementu a marketingu sportovní akce na příkladu Coca-cola školského poháru na léta 2009-2011

    OpenAIRE

    Jeřábek, Petr

    2008-01-01

    - Title: Project of management and marketing of event Coca-cola School Cup in time period 2009-2011 Work goal: Methods: Annotation: Results: Keywords: Analysis ofmarketing and management of event Coca-cola School Cup and advices of innovation for this event. Descriptive analysis, Interview with experts, SWOT analysis. The project Coca-Cola School Cup for the years 2009- 2011 involves innovation approaches in particular manager activities of this sport event. The innovation approaches result f...

  5. La contabilidad ambiental y el impacto financiero de los costos ambientales para el desarrollo sostenible de la empresa multinacional de la industria de bebidas Coca Cola Company en el Ecuador

    OpenAIRE

    Castro Saavedra, Diego Gabriel; Ehmig Dillon, Gunther Pablo

    2014-01-01

    The present study aims to analyse the environmental accounting and the financial impact of the environmental costs for sustainable development of a multinational corporation within the beverage company such as Coca Cola Company in Ecuador. Since 2010, Coca Cola Company in Ecuador performs business operations under the name of Arca Ecuador, which is a part of the Mexican group Arca Continental that manages Coca Cola Brand in Mexico, Argentina and Ecuador. Sustainable development is part of the...

  6. Por trás de uma tampinha de Coca-Cola um mundo de coisas boas!: propaganda no Brasil (1950-1960 = Behind a cover of Coca-Cola a world of good things!: propaganda in Brazil (1950-1960

    Directory of Open Access Journals (Sweden)

    Bammann, Kellen

    2014-01-01

    Full Text Available O artigo tem como fonte de pesquisa os anúncios de Coca-Cola veiculados nas revistas brasileiras O Cruzeiro e Manchete entre 1950 e 1960. O ensaio procura demonstrar de que forma as campanhas publicitárias de Coca-Cola veiculadas nos dois magazines procuraram se adequar aos discursos de valorização da industrialização brasileira. Com o objetivo de evidenciar o auxílio da Coca-Cola no processo industrialização e desenvolvimento do Brasil

  7. [Influence of Coca-Cola on early erosion and surface microhardness of human enamel: an in situ study].

    Science.gov (United States)

    Yuan, M; Zhang, Q; Gao, X J

    2016-06-01

    Assessed the effect of single dose attack of Coca-Cola on early erosion and surface microhardness of permanent human enamel, in order to provide diet instructions on minimum amount and frequency of carbonated beverage consumption. Eighty enamel slabs were prepared out of 10 extracted human mandibular third molars, and distributed into 8 groups with randomized block design(n=10). Ten generally healthy volunteers with normal saliva secretion wore acrylic palatal appliances containing 2 enamel slabs, with formation of a salivary pellicle 2 h ahead. The volunteers were instructed to drink 100 ml fresh Coca-Cola within 20 s. And then the alterations of the enamel slabs were measured using a Vicker's microhardness tester at 1, 2, 4, 6, 8, 10, 20 and 30 min after the consumption of Coca-Cola. For each volunteer, the experiment was carried out in four days, 2 samples were examined each time. Data were analyzed using Kruskal-Wallis and Wilcoxon tests(α =0.05). Significant decreases in surface microhardness(SMH)were observed in each time point(PCoca-Cola could lead to significant decrease of enamel microhardness and initiate erosion of enamel surface. Enamel surface microhardness decreased to the lowest points at 2-8 min, and began to recover after 10 min. The enamel surface microhardness could not fully recovered to the baseline level in 30 min if no intervention was performed.

  8. THE MEDDLING OF THE LANGUAGE FUNCTIONS WHIT THE LEXICAL FIELDS OF THE COCA-COLA BRAND SLOGANS

    Directory of Open Access Journals (Sweden)

    Mărioara VLIONCU

    2013-10-01

    Full Text Available Le but de cet etude a été celui de presenter quelques aspects qui visent la liaison qui peut se faire entre les fonctions de la langue telles comme ells sont théorisées par le linguiste Roman Kakobson et les champs lexicaux des slogans de la marquee « Coca-Cola » qui peut être circonscrite à une structure théorique qui appartient à l’acte communicationnel. Les champs lexicaux d’un objet notionnel, respectivement le boisson gazéifié « Coca-Cola », et une structure théorique spécifique à un acte communicationnel base sur le langage. Pour chaque des fonctions du language, telles comme elles ont été théorisées par le linguiste Roman Jakobson, ont été trouvées des correspondances des champs lexicaux, appartenant aux slogans de la marque « Coca-Cola » . Ces champs lexicaux ont été considérablement étendus par des exemples prépondérente de la sphère verbale.

  9. La decisión de los agricultores del área tropical de Cochabamba (Bolivia) de cultivar coca en lugar de los productos alternativos recomendados por el Estado

    OpenAIRE

    Juan Carlos Barrientos; Walter Schug

    2006-01-01

    A pesar de la prohibición estatal del cultivo de coca desde 1973 y de la reducción rápida de las plantaciones de coca hasta 2002, este arbusto todavía se cultiva en las zonas tropicales de Cochabamba (Bolivia). Tanto aspectos técnicos como económicos, son responsables de que muchos agricultores se decidan por el cultivo de la coca y no por el de cultivos alternativos. Técnicamente, el cultivo de la coca es más adaptable y menos exigente, en comparación con los cinco cultivos alternativos anal...

  10. Coca-Cola Refreshments Class 8 Diesel Electric Hybrid Tractor Evaluation: 13-Month Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Walkowicz, K.; Lammert, M.; Curran, P.

    2012-08-01

    This 13-month evaluation used five Kenworth T370 hybrid tractors and five Freightliner M2106 standard diesel tractors at a Coca Cola Refreshments facility in Miami, Florida. The primary objective was to evaluate the fuel economy, emissions, and operational field performance of hybrid electric vehicles when compared to similar-use conventional diesel vehicles. A random dispatch system ensures the vehicles are used in a similar manner. GPS logging, fueling, and maintenance records and laboratory dynamometer testing are used to evaluate the performance of these hybrid tractors. Both groups drive similar duty cycles with similar kinetic intensity (0.95 vs. 0.69), average speed (20.6 vs. 24.3 mph), and stops per mile (1.9 vs. 1.5). The study demonstrated the hybrid group had a 13.7% fuel economy improvement over the diesel group. Laboratory fuel economy and field fuel economy study showed similar trends along the range of KI and stops per mile. Hybrid maintenance costs were 51% lower per mile; hybrid fuel costs per mile were 12% less than for the diesels; and hybrid vehicle total cost of operation per mile was 24% less than the cost of operation for the diesel group.

  11. On the Pragmatist Translation of the Ads Of Coca-Cola and Pepsi

    Institute of Scientific and Technical Information of China (English)

    覃洁

    2012-01-01

    Advertising language is an important research material of social change, it is picked up conveniently. There is no distortion and glossing over history, it is the most simple and most visual material. For English advertising, it reflects values, aesthetic tastes, lifestyle, cultural traditions in the U.S., Britain and other countries. With their own unique ways of recording social change, English advertising is quietly playing an important role in the social life and the psychology of social culture. As a practical style, the advertising language has its unique characteristics in vocabulary, syntax, rhetoric and other aspects. Leech opened the first systematic study of advertising language. He studied the various features of advertising language from literature perspective. With the emergence of the theories of pragmatics, some Chinese scholars, like Zhao Jing, Huang guowen, also set out to explore the advertising language from different aspects. But few of them devoted themselves to the English advertising of American beverage. This paper sets out to explore the issues from a pragmatics perspective. Based on the characteristics of advertising language of American Coca-Cola and Pepsi, the paper analyzes the inevitable language impact on social functioning and the concept of values between English advertising and the interaction of modem simple life, revealing the failure of English advertising language in cross-cultural exchanges and social pragmatic information.

  12. ANALISIS TOTAL PRODUCTIVE MAINTENANCE PADA LINE 8/CARBONATED SOFT DRINK PT COCA-COLA BOTTLING INDONESIA CENTRAL JAVA

    Directory of Open Access Journals (Sweden)

    Darminto Pujotomo

    2012-02-01

    Full Text Available PT. Coca-Cola Bottling Indonesia (CCBI Central Java merupakan salah satu perusahaan produsen minuman ringan yang terkemuka di Indonesia, dengan dua jenis kelompok produk yang dihasilkan yaitu minuman karbonasi/Carbonated Soft Drink (Coca-Cola, Sprite, dan Fanta dan non-karbonasi (Frestea dan Ades. Dalam usaha untuk mempertahankan mutu dan meningkatkan produktifitas, salah satu faktor yang harus diperhatikan adalah masalah perawatan fasilitas/mesin produksi.  Makalah ini membahas mengenai penyebab dan akibat yang ditimbulkan oleh breakdown mesin terjadi pada Line 8/Carbonated Soft Drink, khususnya pada conveyor, filler machine, dan bottle washer machine. Untuk mendapatkan mesin yang dapat terjaga keterandalannya dibutuhkan suatu konsep yang baik. Total Productive Maintenance (TPM merupakan sebuah konsep yang baik untuk merealisasikan hal tersebut. Konsep ini, selain melibatkan semua personil dalam perusahaan, juga bertujuan untuk merawat semua fasilitas produksi yang dimiliki perusahaan.Data yang digunakan merupakan data breakdown conveyor, filler machine, dan bottle washer machine dari ME Monthly Report PT.CCBI selama bulan Januari-Desember 2005 khususnya line 8. Selain itu makalah ini juga membahas performance maintenance PT. Coca-Cola Bottling Indonesia-Central Java, dengan memperhitungkan nilai Mean Time Beetwen Failure (MTBF, Mean Time To Repair (MTTR, serta Availability mesin, dengan menggunakan data record Line 8 selama bulan Mei 2006 sampai bulan Juli 2006. Sehingga nantinya akan diketahui informasi keadaan aktual dari perusahaan tentang sistem perawatannya, khususnya pada Line 8/Carbonated Soft Drink apakah baik atau buruk. Kata kunci : Total Production Maintenance, Conveyor, Filler Machine, Bottle Washer Machine, Performance Maintenance   PT. Coca-Cola Bottling Indonesia (CCBI-Central Java represent one of notable light beverage producer company in Indonesia, with two product group type yielded is carbonated beverage/Carbonated Soft

  13. Eficacia del programa de reforzamiento comunitario (CRA) más incentivos para el tratamiento de la adicción a la cocaína

    OpenAIRE

    García Rodríguez, Olaya

    2014-01-01

    De acuerdo con el European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), España, junto con Gran Bretaña, es el país con las tasas de consumo de cocaína más altas. Al mismo tiempo, la demanda de tratamiento por abuso de cocaína se ha incrementado de forma muy importante en nuestro país durante los últimos años. Por este motivo, el desarrollo y la diseminación de tratamientos eficaces de la adicción a la cocaína es un asunto de salud pública prioritario en España y en el resto de Eur...

  14. El manejo de contingencias para el tratamiento de la dependencia a la cocaína en la red sanitaria pública

    OpenAIRE

    Zacarés Romaguera, Francisco Damián

    2016-01-01

    De acuerdo con el European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), España, junto con Gran Bretaña, es el país con las tasas de consumo de cocaína más altas. Al mismo tiempo, la demanda de tratamiento por abuso de cocaína se ha incrementado de forma muy importante en nuestro país durante los últimos años. Por este motivo, el desarrollo y la diseminación de tratamientos eficaces de la adicción a la cocaína es un asunto de salud pública prioritario en España y en el resto de Eur...

  15. Process evaluation of knowledge transfer across industries: Leveraging Coca-Cola's supply chain expertise for medicine availability in Tanzania.

    Science.gov (United States)

    Linnander, Erika; Yuan, Christina T; Ahmed, Shirin; Cherlin, Emily; Talbert-Slagle, Kristina; Curry, Leslie A

    2017-01-01

    Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania's Medical Stores Department (MSD). We conducted a process evaluation including in-depth interviews with 70 participants between July 2011 and May 2014, corresponding to each phase of the partnership, with focus on challenges and strategies to address them, as well as benefits perceived by partners. Partners faced challenges in (1) identifying relevant knowledge to transfer, (2) translating operational solutions from Coca-Cola to MSD, and (3) maintaining momentum between project phases. Strategies to respond to these challenges emerged through real-time problem solving and included (1) leveraging the receptivity of MSD leadership, (2) engaging a boundary spanner to identify knowledge to transfer, (3) promoting local recognition of commonalities across industries, (4) engaging external technical experts to manage translation activities, (5) developing tools with visible benefits for MSD, (6) investing in local relationships, and (7) providing time and space for the partnership model to evolve. Benefits of the partnership perceived by MSD staff included enhanced collaboration and communication, more proactive orientations in managing operations, and greater attention to performance management. Benefits perceived by Coca-Cola staff included strengthened knowledge transfer capability and enhanced job satisfaction. Linking theoretical constructs with practical experiences from the field, we highlight the challenges, emergent strategies, and perceived benefits of a partnership

  16. Process evaluation of knowledge transfer across industries: Leveraging Coca-Cola’s supply chain expertise for medicine availability in Tanzania

    Science.gov (United States)

    Yuan, Christina T.; Ahmed, Shirin; Cherlin, Emily; Talbert-Slagle, Kristina; Curry, Leslie A.

    2017-01-01

    Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania’s Medical Stores Department (MSD). We conducted a process evaluation including in-depth interviews with 70 participants between July 2011 and May 2014, corresponding to each phase of the partnership, with focus on challenges and strategies to address them, as well as benefits perceived by partners. Partners faced challenges in (1) identifying relevant knowledge to transfer, (2) translating operational solutions from Coca-Cola to MSD, and (3) maintaining momentum between project phases. Strategies to respond to these challenges emerged through real-time problem solving and included (1) leveraging the receptivity of MSD leadership, (2) engaging a boundary spanner to identify knowledge to transfer, (3) promoting local recognition of commonalities across industries, (4) engaging external technical experts to manage translation activities, (5) developing tools with visible benefits for MSD, (6) investing in local relationships, and (7) providing time and space for the partnership model to evolve. Benefits of the partnership perceived by MSD staff included enhanced collaboration and communication, more proactive orientations in managing operations, and greater attention to performance management. Benefits perceived by Coca-Cola staff included strengthened knowledge transfer capability and enhanced job satisfaction. Linking theoretical constructs with practical experiences from the field, we highlight the challenges, emergent strategies, and perceived benefits of a

  17. Process evaluation of knowledge transfer across industries: Leveraging Coca-Cola's supply chain expertise for medicine availability in Tanzania.

    Directory of Open Access Journals (Sweden)

    Erika Linnander

    Full Text Available Persistent gaps in the availability of essential medicines have slowed the achievement of global health targets. Despite the supply chain knowledge and expertise that ministries of health might glean from other industries, limited empirical research has examined the process of knowledge transfer from other industries into global public health. We examined a partnership designed to improve the availability of medical supplies in Tanzania by transferring knowledge from The Coca-Cola system to Tanzania's Medical Stores Department (MSD. We conducted a process evaluation including in-depth interviews with 70 participants between July 2011 and May 2014, corresponding to each phase of the partnership, with focus on challenges and strategies to address them, as well as benefits perceived by partners. Partners faced challenges in (1 identifying relevant knowledge to transfer, (2 translating operational solutions from Coca-Cola to MSD, and (3 maintaining momentum between project phases. Strategies to respond to these challenges emerged through real-time problem solving and included (1 leveraging the receptivity of MSD leadership, (2 engaging a boundary spanner to identify knowledge to transfer, (3 promoting local recognition of commonalities across industries, (4 engaging external technical experts to manage translation activities, (5 developing tools with visible benefits for MSD, (6 investing in local relationships, and (7 providing time and space for the partnership model to evolve. Benefits of the partnership perceived by MSD staff included enhanced collaboration and communication, more proactive orientations in managing operations, and greater attention to performance management. Benefits perceived by Coca-Cola staff included strengthened knowledge transfer capability and enhanced job satisfaction. Linking theoretical constructs with practical experiences from the field, we highlight the challenges, emergent strategies, and perceived benefits of a

  18. Quantitative capillary electrophoresis and its application in analysis of alkaloids in tea, coffee, coca cola, and theophylline tablets.

    Science.gov (United States)

    Li, Mengjia; Zhou, Junyi; Gu, Xue; Wang, Yan; Huang, Xiaojing; Yan, Chao

    2009-01-01

    A quantitative CE (qCE) system with high precision has been developed, in which a 4-port nano-valve was isolated from the electric field and served as sample injector. The accurate amount of sample was introduced into the CE system with high reproducibility. Based on this system, consecutive injections and separations were performed without voltage interruption. Reproducibilities in terms of RSD lower than 0.8% for retention time and 1.7% for peak area were achieved. The effectiveness of the system was demonstrated by the quantitative analysis of caffeine, theobromine, and theophylline in real samples, such as tea leaf, roasted coffee, coca cola, and theophylline tablets.

  19. Brand Sponsorship and Social Media. Coca Cola and Carlsberg Illustrated with an Example of the European Football Championship 2016

    OpenAIRE

    Komańda, Marcin

    2017-01-01

    Purpose of the article: Presentation of the issue of brand sponsorship of events in the light of the use of social media for the purposes of brand management in the customer-based brand equity paradigm. Methodology/methods: Two brands (CocaCola and Carlsberg) which were the official sponsors of a sports event (EURO 2016) were monitored in social media. For this purpose information gathered by socialmention.com and likemore.pl were used. Presentation of the results of the ana...

  20. The Comparative Analysis of Packaging Design Element to Purchasing Decision Between Coca Cola and Big Cola in Manado

    OpenAIRE

    Gessal, Putri

    2013-01-01

    Packaging can play a very interesting role in the success or failure of a product. Its success depends a lot on how it is designed by its creators. Packaging function to protect the contents of a product lies within the package design. It has the power to influence your choices, and with its carefully thought-out aesthetics can affect your emotions. This aim of the study comparative analysis of packaging design element to purchase decision between Coca Cola and Big Cola with packaging element...

  1. Analisis Pengaruh Penerapan Sistem Manajemen Keselamatan dan Kesehatan Kerja OHSAS 18001 Terhadap Produktivitas Kerja Karyawan PT. Coca Cola Amatil Medan

    OpenAIRE

    Sitorus, Ummi Salamah

    2016-01-01

    Basically to doing his job, employees are not immune from the called risk in the work. Both the level of risk in mild or severe. To minimize the risk of loss is required a management system for managing safety and health of employees in order to increase employee productivity so companies can compete with other companies. In this case PT. Coca Cola Amatil Medan implement a safety and health Management System (SMK3) OHSAS 18001. The method used is quantitative research with assosiative app...

  2. Utilização do agonista dopaminérgico pergolida no tratamento da "fissura" por cocaína

    Directory of Open Access Journals (Sweden)

    Focchi Guilherme R de Azevedo

    2001-01-01

    Full Text Available OBJETIVOS: O estudo avaliou a eficácia e a segurança terapêutica do agonista dopaminérgico pergolida no tratamento ambulatorial da ''fissura" por cocaína. MÉTODOS: Participaram de estudo controlado simples-cego, com duração de quatro semanas, em tratamento ambulatorial, 42 pacientes do sexo masculino com idade entre 18 e 50 anos, com diagnóstico de dependência de cocaína pelo DSM-IV e primeiro grau completo. Transtornos clínicos e/ou psiquiátricos que necessitassem de internação, uso de medicação psiquiátrica, quadros psicóticos prévios independentes do consumo de cocaína e hipersensibilidade à pergolida foram critérios de exclusão. Os pacientes foram divididos aleatoriamente em dois grupos: o primeiro recebeu pergolida (0,05-0,2 mg ao dia, e o segundo, placebo (1 a 4 comprimidos ao dia. Os grupos foram comparados quanto à ''fissura'' por cocaína e aos efeitos colaterais das medicações. RESULTADOS: Não foram encontradas diferenças estatisticamente significativas entre os dois grupos em relação à incidência de efeitos colaterais ou ao relato da redução da ''fissura'' por cocaína. CONCLUSÃO: A amostra pequena e o uso de medicação por tempo curto podem ter influído nos resultados. A pergolida se mostrou segura, com poucos efeitos colaterais. A pergolida não se mostrou superior ao placebo no tratamento da "fissura" por cocaína.

  3. Comunicació de crisi en conflictes laborals : la comunicació durant l’ERO de Coca-Cola Iberian Partners

    OpenAIRE

    Garcés González, Miriam

    2016-01-01

    Un conflicte laboral com un ERO pot derivar en una veritable crisi per a una empresa. En aquest context, la comunicació pren un paper rellevant en l'organització, emmarcada en la comunicació de crisi. Un cas recent és la crisi soferta per l'ERO de Coca-Cola Iberian Partners, embotelladora per a la marca Coca-Cola a territori espanyol. Aquesta investigació se centra en la comunicació que es va produir durant aquest conflicte laboral, a través d'una anàlisi de contingut de notícies sobre l'ERO ...

  4. Analisis Perbandingan Pendanaan Leasing Dan Hutang Jangka Panjang Dalam Pengadaan Aktiva Tetap (Studi Pada Koperasi Karyawan Coca-cola Jawa Timur)

    OpenAIRE

    Marchelia, Yusina Fitri

    2014-01-01

    This research aims to know the more efficient and profiting funding between leasing funding compared to long term debt in procurement of fixed assets on cooperative employees of Coca Cola East Java. The type of research used in this research is a descriptive research. While, the approach used in this research is financial quantitative approach.The cooperative employees of Coca Cola East Java have plans for procurement of fixed assets in form of vehicles worth Rp. 568.850.000 that will be fund...

  5. Narcotráfico y conflicto: ¿por qué bajó el precio de la cocaína?

    Directory of Open Access Journals (Sweden)

    Leonardo Raffo López

    2010-12-01

    Full Text Available Conjugando el enfoque de Ortiz con el de Mejía et al. este ensayo propone un nuevo modelo de narcotráfico y conflicto. En un marco de equilibrio general elabora una explicación del descenso del precio de la cocaína en las dos últimas décadas. El modelo muestra que la causa fundamental de esa tendencia es el aumento de la productividad de las actividades ilícitas, que ha contrarrestado los efectos de las políticas de represión de la oferta y el descenso registrado de la superficie de cultivos de coca.

  6. Stilistiskie izteiksmes līdzekļi Coca-Cola reklāmas plakātos

    OpenAIRE

    Gudre, Anete

    2017-01-01

    Šajā darbā tika pētīti mākslinieciskie un fonētiskie stila izteiksmes līdzekļi un to lietojums Coca-Cola reklāmas plakātos. Kā arī tika analizēti Coca-Cola reklāmas plakātu vizuālie elementi. Tēma tika izvēlēta, lai redzētu atšķirību starp mākslinieciskās izteiksmes līdzekļiem un, lai redzētu, cik bieži tie tiek izmantoti izvēlētajos reklāmas plakātos. Darbā tika aplūkoti vispopulārākie mākslinieciskās izteiksmes līdzekļi – metafora, epitets, personifikācija un hiperbola. Multimediju analīze ...

  7. Vasculite cerebral e uso de cocaína e crack Cerebral vasculitis and cocaine and crack abuse

    Directory of Open Access Journals (Sweden)

    Fernando Madalena Volpe

    1999-09-01

    Full Text Available O abuso de cocaína e crack está associado com importante parcela dos acidentes vasculares cerebrais, especialmente em pacientes jovens. O presente estudo relata o caso de um usuário de cocaína e crack que desenvolveu vasculite do sistema nervoso central, resultando em infartos cerebrais e edema extensos, levando à demência com alterações comportamentais e convulsões. Ressalta-se a importância de suspeitar do uso de drogas em jovens que se apresentam com acidente vascular cerebral, assim como avaliar possíveis lesões cerebrais em usuários de drogas com deterioração cognitiva.Cocaine and crack abuse is strongly related to stroke, particularly in young patients. The present study reports the case of a cocaine and crack abuser who developed central nervous system vasculitis, resulting in extensive cerebral infarctions, leading to dementia, behavioural disturbances and seizures. The relevance of detecting drug abuse in young stroke patients is stressed. Assessing possible brain lesions in drug abusers with cognitive impairment is also important.

  8. Propuesta de un modelo ecosistémico para la cadena productiva de la coca con fines alternativos en Colombia

    Directory of Open Access Journals (Sweden)

    Alexandra Montoya-Restrepo

    2018-01-01

    Full Text Available La investigación tuvo como objetivo proponer una alternativa socioeconómica para la producción de hoja de coca en Colombia. Metodología: A partir de las propiedades industriales de la planta y sus usos ancestrales se propone la utilización del modelo de integración organizacional para el apoyo de los actuales cultivadores que tienen como único sustento este sistema productivo, ilícito en el país, pero que encuentran en peligro real de perder su capacidad productiva. Resultados: estudios actuales han determinado propiedades industriales farmacéuticas y agrícolas de la planta, con lo cual se puede realizar una integración empresarial. Conclusiones: A partir del modelo propuesto, es posible encontrar alternativas para la solución del cultivo ilícito de hoja de coca en el país, con un modelo de encadenamiento organizacional y productivo.

  9. La hoja transfronteriza. El consumo de coca en las faenas mineras salitreras en el Norte Grande de Chile (1900-1930

    Directory of Open Access Journals (Sweden)

    Sergio González Miranda

    2016-01-01

    Full Text Available Bolivian workers have crossed the Andes and participated in the nitrate-mining projects from the beginning of the cycle of expansion of that industry in the 19th century until its definitive ending with the crisis of 1930. Along with the arrival of these workers in the towns and camps of Tarapacá and Antofagasta, came a variety of goods that formed an essential part of their diet, including coca leaves. Although the consumption of this product is associated with high-altitude mining and underground mining, this article studies the importance it had in desert and open-pit mining. It also analyzes the commerce of coca in the local stores known as pulperías, and the opinion of public officials regarding the social and labor impact of this cross-border leaf. A historiographical study was done of press archives and official documents located in Chile and Bolivia, to contrast the hypotheses on the subject, leading to conclude that the consumption of coca was generalized among workers of almost all types in the nitrate-mining industry. With respect to nationalities, the consumption of coca was not limited exclusively to Bolivians, but was common among Peruvian and Chilean workers as well.

  10. Repercussões otorrinolaringológicas do abuso de cocaína e/ou crack em dependentes de drogas

    Directory of Open Access Journals (Sweden)

    Nassif Filho A.C.N.

    1999-01-01

    Full Text Available A prevalência de pacientes viciados em cocaína e/ou crack parece estar aumentando; portanto, o médico deve estar preparado para diagnosticar o uso de drogas. OBJETIVOS. Determinar se existem sinais típicos de uso de cocaína e/ou crack no trato respiratório superior ou na orofaringe em exame otorrinolaringológico comum. Orientar o médico no diagnóstico dos pacientes viciados nessas drogas. MÉTODOS. Foram estudados 18 pacientes viciados em cocaína e/ou crack, que estavam internados em clínica psiquiátrica, através de anamnese e exame otorrinolaringológico simples (rinoscopia anterior e orofaringoscopia. RESULTADOS. Foi impossível estabelecer uma correlação entre o tempo de uso, quantidade e freqüência no uso das drogas quanto aos sintomas e exame otorrinolaringológico. CONCLUSÃO. Devido à inespecíficidade no exame otorrinolaringológico do paciente viciado em cocaína e/ou crack, é necessário que o médico suspeite do abuso de drogas na história clínica; caso contrário, poderá não realizar este importante diagnóstico.

  11. Oesophageal and gastric potential difference and pH in healthy volunteers following intake of coca-cola, red wine, and alcohol.

    Science.gov (United States)

    Rubinstein, E; Hauge, C; Sommer, P; Mortensen, T

    1993-01-01

    Alcohol causes gastroesophageal reflux and mucosal damage in the oesophagus and the stomach. The transmucosal electrical potential difference gives information on gastric mucosal integrity and function, while the validity of oesophageal measurements have been discussed. Baseline oesophageal potential difference measurements were performed three times with an interval of at least one week. We found oesophageal potential difference measurements reliable with an acceptable reproducibility. Oesophageal and gastric potential difference and pH were measured by use of a new microelectrode principle in 10 healthy volunteers following intake of coca-cola, wine and alcohol. Oesophageal and gastric potential difference decreased after intake of 250 ml coca-cola, 250 ml 11 vol% red wine and 60 ml 43 vol% whisky. Gastric potential difference decreased after intake of 250 ml ethanol 11 vol% and 60 ml ethanol 43 vol%. Intake of red wine and whisky resulted in a significant greater gastric potential difference decrease compared to similar concentrations and volumes of ethanol. The time until the potential difference had regained baseline level was longer after intake of red wine compared to coca-cola, whisky and ethanol. Oesophageal pH decreased after intake of coca-cola and red wine, but was unchanged after whisky. Gastric pH was unchanged after intake of all the drinks. In conclusion, the gastric potential difference reduction was not correlated to alcohol concentration. Red wine seems to affect the gastric potential difference more than coca-cola, whisky and ethanol. The observed changes in oesophageal and gastric potential difference might be due to changes in Cl- secretion and/or due to a damaging effect of the additives of the beverages.

  12. A prospective randomized trial on the use of Coca-Cola Zero(®) vs water for polyethylene glycol bowel preparation before colonoscopy.

    Science.gov (United States)

    Seow-En, I; Seow-Choen, F

    2016-07-01

    The study aimed to determine whether Coca-Cola (Coke) Zero is a safe and effective solvent for polyethylene glycol (PEG). Between December 2013 and April 2014, 209 healthy adults (115 men, 95 women) scheduled for elective colonoscopy were randomized to use either Coke Zero (n = 100) or drinking water (n = 109) with PEG as bowel preparation. Each patient received two sachets of PEG to dissolve in 2 l of solvent, to be completed 6 h before colonoscopy. Serum electrolytes were measured before and after preparation. Bowel cleanliness and colonoscopy findings were recorded. Palatability of solution, adverse effects, time taken to complete and willingness to repeat the preparation were documented via questionnaire. Mean palatability scores in the Coke Zero group were significantly better compared with the control group (2.31 ± 0.61 vs 2.51 ± 0.63, P = 0.019), with a higher proportion willing to use the same preparation again (55% vs 43%). The mean time taken to complete the PEG + Coke Zero solution was significantly faster (74 ± 29 min vs 86 ± 31 min, P = 0.0035). The quality of bowel cleansing was also significantly better in the Coke Zero group (P = 0.0297). There was no difference in the frequency of adverse events (P = 0.759) or the polyp detection rate (32% vs 31.2%). Consumption of either preparation did not significantly affect electrolyte levels or hydration status. Coke Zero is a useful alternative solvent for PEG. It is well tolerated, more palatable, leads to quicker consumption of the bowel preparation and results in better quality cleansing. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.

  13. PERANCANGAN MEJA ADJUSTABLE DENGAN MEMPERHATIKAN POSTUR KERJA PEKERJA MANUAL MATERIAL HANDLING (Studi Kasus di PT. Coca – Cola Bottling Indonesia

    Directory of Open Access Journals (Sweden)

    Singgih Saptadi

    2012-02-01

    Full Text Available PT Coca Cola Bottling Indonesia adalah salah satu perusahaan yang bergerak dalam bidang minuman ringan baik berupa carbonated soft drink (coca-cola, fanta, sprite maupun non-carbonated soft drink (frestea, ades. Penanganan material pada pabrik ini masih dilakukan secara manual (Manual Material Handling/MMH. Pekerjaan ini dimulai dengan pengangkatan kontainer dari atas conveyor kemudian dipindahkan dan disusun di atas pallet (proses palletizing.Rapid Entire Body Assessment (REBA adalah salah satu metode yang digunakan untuk menilai postur kerjakaitanya dengan cedera otot akibat bekerja. Pada metode ini juga dipengaruhi oleh faktor coupling, beban eksternal serta aktivitas pekerja yang dialami oleh subjek pengamatan. Implementasi REBA dilakukan pada postur penanganan material khususnya pada pengangkatan krat dan penyusunan krat. Dari hasil penilaian menunjukkan action level didominasi pada level 3 dan level 4, untuk itu perlu dilakukan tindakan perbaikan segera/saat itu juga. Dalam melakukan rekomendasi perbaikan postur penulis melakukan perancangan fasilitas yang disesuaikan dengan data antropometri dan didasarkan pada jenis aktifitasnya serta memberikan usulan fasilitas berupa meja adjustable. Penulis memvisualisasikan hasil rancangan melalui sofware 3DS max, dimana sofware ini juga digunakan sebagai analisis postur pada fasilitas kerja usulan. Kata kunci : Manual Material Handling, REBA, perancangan fasilitas kerja, meja adjustable, 3DS max                Coca Cola Bottling Indonesia is one of the company which move on soft drink areas like carbonated soft drinks (coca-cola, fanta, sprite or non-carbonated soft drinks (frestea,ades. Material handling in this factory is still done manually. This work is started by lifting the container from conveyor  then move it and arrange it above the pallet ( proses palletizing.              Rapid Entire Body Assesment ( REBA is one of the method by which is used to score working

  14. Polimorfismos del gen Butirilcolinesterasa responsables de reacciones adversas en pacientes consumidores de “cocaína”

    OpenAIRE

    Estrada Serrato, Carlos

    2014-01-01

    La butirilcolinesterasa humana (BChE; EC 3.1.1.8) es una enzima polimórfica sintetizada en el hígado y en el tejido adiposo, ampliamente distribuida en el organismo y encargada de hidrolizar algunos ésteres de colina como la procaína, ésteres alifáticos como el ácido acetilsalicílico, fármacos como la metilprednisolona, el mivacurium y la succinilcolina y drogas de uso y/o abuso como la heroína y la cocaína. Es codificada por el gen BCHE (OMIM 177400), habiéndose identificado más de 100 varia...

  15. Brand Sponsorship and Social Media. Coca Cola and Carlsberg Illustrated with an Example of the European Football Championship 2016

    Directory of Open Access Journals (Sweden)

    Marcin Komańda

    2017-06-01

    Full Text Available Purpose of the article: Presentation of the issue of brand sponsorship of events in the light of the use of social media for the purposes of brand management in the customer-based brand equity paradigm. Methodology/methods: Two brands (CocaCola and Carlsberg which were the official sponsors of a sports event (EURO 2016 were monitored in social media. For this purpose information gathered by socialmention.com and likemore.pl were used. Presentation of the results of the analysis required the use of descriptive statistics as well as the Wilcoxon test and a network graph. Scientific aim: Determination of the scope and nature of the influence of sponsorship of an international sports event on the way a brand is perceived by social media users based on a selected set of data derived from brand monitoring. Findings: In case of Carlsberg the attitude of social media users did not change during EURO 2016, however, majority of their statements was connected with the issues related to this sports event. In case of Coca Cola, the perception of the brand by its clients changed within the studied period of time, however, the issues related to EURO 2016 were only one of many other issues raised by them. Conclusions: Assessment of the influence of brand sponsorship of an event on social media users’ perception faces the following difficulties: scope of monitoring, its efficiency, choice of data set generated by the monitoring tool for the analysis, level of recognition of brands and brand multi-sponsorship (parallel engagement of the brand in many events.

  16. Effect of calcium lactate in erosion and S. mutans in rats when added to Coca-Cola.

    Science.gov (United States)

    Beiraghi, S; Atkins, S; Rosen, S; Wilson, S; Odom, J; Beck, M

    1989-12-01

    Thirty-six Sprague Dawley rats, 22 days of age, were divided randomly into three groups of 12 each and housed in a programmable feeder. The three experimental groups received either Coca-Cola (CC), Coca-Cola with calcium lactate (CC-CaL), or distilled water. The programmable feeder was set to deliver 17 equal volumes of fluid per day with each feeding period lasting between 80-90 min. All groups were given Diet MIT 305 in one premeasured amount per 24 hr period (ad libitum). The pH of the CC with calcium lactate was adjusted to match the CC without calcium lactate by the addition of citric and phosphoric acids. The test period lasted five weeks. Each week, the food and fluid consumed and the weight gain were measured. Erosion of the teeth was scored by the method of Restarski et al. (1945). ANOVA indicated that there was a significant difference in the amount of erosion among groups. A Newman-Keuls analysis showed that the mean erosion score of the CC group was significantly greater (P less than 0.05) than that of the CC-CaL and distilled water groups (54.2 +/- 0.12; 0.0275 +/- 0.0123; 0.132 +/- 0.070, respectively). There was no significant difference in erosion between the CC-CaL and distilled water groups. There was no difference in the amount of food and fluid consumed among the group of rats. In conclusion, calcium lactate added to CC resulted in significantly reduced tooth erosion in rats.

  17. Análisis de cocaína en diferentes muestras por cromatografía de gases con detector de ionización de llama (CG-FID)

    OpenAIRE

    Ángela M. López C.; William F. Garzón M; Milton Rosero-Moreano; Gonzalo Taborda O.

    2015-01-01

    En este estudio se realizó la validación de los métodos establecidos por la UNODC para la cuantificación y extracción de benzometilecgonina (cocaína) presente en las hojas de Erythhroxylum coca, en té de coca y en clorhidrato de cocaína. El primer método de extracción, recomendado por la UNODC, es una extracción solido-líquido (ESL), sin embargo, los resultados obtenidos indican que esta no es lo suficientemente eficiente para lograr una señal de analito distinguible de la relación señal a ru...

  18. Análisis de cocaína en diferentes muestras por cromatografía de gases con detector de ionización de llama (CG-FID

    Directory of Open Access Journals (Sweden)

    Ángela M. López C.

    2015-01-01

    Full Text Available En este estudio se realizó la validación de los métodos establecidos por la UNODC para la cuantificación y extracción de benzometilecgonina (cocaína presente en las hojas de Erythhroxylum coca, en té de coca y en clorhidrato de cocaína. El primer método de extracción, recomendado por la UNODC, es una extracción solido-líquido (ESL, sin embargo, los resultados obtenidos indican que esta no es lo suficientemente eficiente para lograr una señal de analito distinguible de la relación señal a ruido (S/N para las muestras de hojas de Erythhroxylum coca y té de coca. El segundo método propuesto es la extracción soxhlet, los resultados indican que esta resulta más eficiente para aislar y cuantificar el analito de interés por cromatografía de gases acoplada a un detector de ionización por llama (CG-FID. Después de someter las muestras al proceso de extracción soxhlet y cuantificación por CG-FID se encontró que la hoja de té posee 7,66×102 mg de cocaína/kg de muestra, las hojas de coca 17,15 mg de cocaína/kg de muestra y el clorhidrato de cocaína 7,15×105 mg de cocaína/kg de muestra. El método de análisis escogido se caracteriza por arrojar bajos límites de detección (0,169 mg/L y por poseer parámetros estadísticos y cromatográficos ideales.

  19. Respektování lidských práv a transnacionální korporace: Případová studie Coca-cola

    OpenAIRE

    Hyšková, Kateřina

    2017-01-01

    This bachelor thesis deals with the issue of violation of human rights by transnational corporations on a case of Coca-Cola. The theoretical part explains the international legal responsibility of individual subjects of the international environment and the issue of non-binding international legal standards for the issue of transnational corporations and human rights. In the empirical part, the thesis tries to answer the question of to what extent and which specific human rights Coca-Cola vio...

  20. Gastric Outlet Obstruction--An Unexpected Complication during Coca-Cola Therapy for a Gastric Bezoar: A Case Report and Literature Review.

    Science.gov (United States)

    Lu, Lei; Zhang, Xiao-Feng

    2016-01-01

    Gastric bezoars are concretions of undigested material, and Coca-Cola therapy is an easy, efficacious and safe approach for bezoar treatment. Gastric outlet obstruction due to a migratory gastric bezoar during Coca-Cola therapy is an uncommon presentation and, to the best of our knowledge, no cases have been previously reported. We herein describe one such case with no known predisposing factors that recovered via the endoscopic technique. A thorough literature search was performed, which yielded eight relevant patients from seven publications, all of who developed gastrointestinal obstruction during dissolution treatment and recovered uneventfully after surgical intervention. In conclusion, this potential complication should be kept in mind in the event that alternative treatment is necessary.

  1. ¿Estaba intoxicado por cocaína este individuo? (I): estimaciones basadas en la farmacocinética de la droga

    OpenAIRE

    A. Ortega Pérez

    2003-01-01

    La cocaína tiene mucho interés para los médicos forenses a causa de la frecuencia de su uso, de su toxicidad y de su implicación en hechos violentos. Con el fin de ayudar a dictaminar si existió una intoxicación por la droga se exponen los datos disponibles sobre su farmacocinética. La droga puede absorberse por varias vías, alcanzando concentraciones sanguíneas apreciables casi inmediatamente y las concentraciones máximas en pocos minutos o en una hora, según la vía. La cocaína tiene una sem...

  2. Vartotojų požiūrio formavimas reklamos priemonėmis: „Coca-Cola“ pavyzdžiu

    OpenAIRE

    Kučkovaitė, Agnė

    2018-01-01

    Šio darbo tikslas – ištirti Lietuvos gyventojų požiūrį į reklamą ir pateikti „Coca-Cola“ įmonei pasiūlymus kaip tinkamiausiu būdu reklamuoti savo paslaugas internete. Darbas sudarytas iš trijų dalių. Pirmoje dalyje teoriniu aspektu apibūdinama ir palyginama su kitomis reklamos priemonėmis reklama internete, jos privalumai, trūkumai ir perspektyvos. Antroje dalyje pristatoma „Coca-Cola“ įmonė, analizuojami Lietuvos gyventojų požiūrio į reklamą internete tyrimo rezultatai, nustatomi tinka...

  3. Estudos epigenéticos em dependentes de crack e cocaína: investigação da metilação global do genoma

    OpenAIRE

    Caroline Perez Camilo

    2015-01-01

    INTRODUÇÃO: A expansão e disseminação do consumo de crack e cocaína no Brasil vem se tornando um grave problema de saúde pública nos últimos vinte anos. Diferentes abordagens biológicas têm sido investigadas utilizando o fenótipo de abuso/dependência de crack/cocaína, cujos resultados têm demonstrado a participação importante do substrato genético, assim como a sua interação com os fatores ambientais no desenvolvimento desse transtorno. OBJETIVOS: Investigar o padrão de metilação do DNA do ge...

  4. Prenatal dietary load of Maillard reaction products combined with postnatal Coca-Cola drinking affects metabolic status of female Wistar rats.

    Science.gov (United States)

    Gurecká, Radana; Koborová, Ivana; Janšáková, Katarína; Tábi, Tamás; Szökő, Éva; Somoza, Veronika; Šebeková, Katarína; Celec, Peter

    2015-04-01

    To assess the impact of prenatal exposure to Maillard reaction products (MRPs) -rich diet and postnatal Coca-Cola consumption on metabolic status of female rats. Diet rich in MRPs and consumption of saccharose/fructose sweetened soft drinks is presumed to impose increased risk of development of cardiometabolic afflictions, such as obesity or insulin resistance. At the first day of pregnancy, 9 female Wistar rats were randomized into two groups, pair-fed either with standard rat chow (MRP-) or MRPs-rich diet (MRP+). Offspring from each group of mothers was divided into two groups and given either water (Cola-) or Coca-Cola (Cola+) for drinking ad libitum for 18 days. Oral glucose tolerance test was performed, and circulating markers of inflammation, oxidative stress, glucose and lipid metabolism were assessed. MRP+ groups had higher weight gain, significantly so in the MRP+/Cola- vs MRP-/Cola-. Both prenatal and postnatal intervention increased carboxymethyllysine levels and semicarbazide-sensitive amine oxidase activity, both significantly higher in MRP+/Cola + than in MRP-/Cola-. Total antioxidant capacity was lower in MRP+ groups, with significant decrease in MRP+/Cola + vs MRP-/Cola+. Rats drinking Coca-Cola had higher insulin, homeostatic model assessment of insulin resistance, heart rate, advanced oxidation of protein products, triacylglycerols, and oxidative stress markers measured as thiobarbituric acid reactive substances compared to rats drinking water, with no visible effect of MRPs-rich diet. Metabolic status of rats was affected both by prenatal and postnatal dietary intervention. Our results suggest that combined effect of prenatal MRPs load and postnatal Coca-Cola drinking may play a role in development of metabolic disorders in later life.

  5. Penerapan Diagram Kontrol D^2 Mahalanobis Pada Proses Produksi Minuman Kemasan Returnable Glass Bottle (Studi Kasus Di PT. Coca-cola Bottling Indonesia Central Java)

    OpenAIRE

    Muhyidin, Muhammad Abid; Safitri, Diah; Rahmawati, Rita

    2014-01-01

    Quality being one of the basic factors in choosing a product consumers. Therefore, an industry or a company should always maintain the quality of their products in order to get loyal customers and are able to survive in the competitive market. Coca-cola Bottling Indonesia Central Java Limited Compay is one of the manufacturing company engaged in the beverage packaging industry and always trying to improve the quality for customer satisfaction. Although it has been to improve the quality, the...

  6. Perlakuan Akuntansi Aktiva Tetap Dan Metode Penyusutan Yang Sesuai Dengan Standar Akuntansi Keuangan Pada PT. Coca Cola Bottling Company Indonesia Medan

    OpenAIRE

    Tarigan, Yulinda

    2011-01-01

    This study aims to obtain a clear picture of the policy of fixed assets employed by PT Coca Cola Bottling Company of Indonesia Medan, such as how the acquisition of fixed assets, expenses after the acquisition of fixed assets, fixed assets depreciation method, the withdrawal of fixed assets, as well as the presentation of fixed assets those in the financial statements are appropriate depreciation method and the Financial Accounting Standards. In a study conducted, the author uses descripti...

  7. Abordagens metodológicas que auxiliam na identificação química da cocaína apreendida no Brasil

    Directory of Open Access Journals (Sweden)

    Isaias da Silva Freitas

    2017-09-01

    Full Text Available O tráfico de drogas proscritas no Brasil tem aumentado consideravelmente. Um dos reflexos desse crescimento se dá pelo quantitativo apreendido pelos órgãos de segurança pública de drogas sintéticas, canabinóides e, em sua maioria, por cocaína. O Brasil encontra-se geograficamente localizado em uma área onde o cultivo de espécies da família Erythroxylaceae é beneficiado, além disso, faz fronteiras com os principais países produtores de cocaína no mundo, o que dificulta, sobremaneira, o combate ao seu tráfico. As polícias federal e civil têm identificado, constantemente, novos fornecedores e novos locais de refino de cocaína, logo, a identificação das rotas de tráfico, origem geográfica e dos seus distribuidores torna-se cada vez mais complexa exigindo dos órgãos de segurança pública e da comunidade forense em geral um melhor aprimoramento de suas metodologias de identificação e quantificação, de forma a fornecerem informações conclusivas para o combate ao seu tráfico. Assim, nesse trabalho, foram avaliadas as principais abordagens metodológicas que contribuem para a elucidação da identificação das amostras de cocaína apreendida no país.

  8. Marketingové strategie značek Coca-Cola, Pepsi a Kofola na českém trhu

    OpenAIRE

    Tvrdý, Aleš

    2014-01-01

    This diploma thesis in the first chapter characterises the concepts of brand and marketing strategy including their main components. In the second chapter deals with the brands Coca-Cola, Pepsi and Kofola and their elements, image, positioning and marketing mix. In the final part, the results of two surveys are presented - a survey of the retail chains and a survey among consumers of those brands, which are dealing with analysis of the market positiong of those brands and their perception by ...

  9. Entidades clínicas cardiovasculares asociadas al consumo de cocaína por vía nasal en una población peruana

    Directory of Open Access Journals (Sweden)

    Luis Razzeto-Ríos

    2008-06-01

    Full Text Available Objetivos: Conocer la frecuencia de entidades clínicas cardiovasculares asociadas al empleo de cocaína por vía nasal en consumidores peruanos. Diseño: Estudio prospectivo, descriptivo, tipo serie de casos. Lugar: Hospital Edgardo Rebagliati Martins, EsSalud, hospital docente, y Clínica San Felipe. Participantes: Pacientes atendidos entre los años 1991 y 2006. Principales medidas de resultados: Síntomas y entidades clínicas asociadas al consumo de cocaína vía nasal. Resultados: En los 63 pacientes evaluados, la mediana de edad fue 35 años, 53 (84% eran de sexo masculino, 86% afirmó haber ingerido cocaína previamente. Los síntomas aparecieron antes de las 2 horas en 78% de los pacientes y 81% presentó trastornos del electrocardiograma. Los síntomas reportados fueron dolor torácico (59%, palpitaciones (27%, convulsiones (5%, hipertermia (3% y cefalea (6%. Las entidades clínicas asociadas fueron: síndromes coronarios agudos (49%, arritmia ventricular (25%, infarto agudo de miocardio (10%, crisis hipertensiva (5% y muerte súbita (11%. Durante el seguimiento, la reincidencia en el consumo se produjo en 76%, siendo esta predominantemente en los primeros 6 meses (63%. Conclusiones: El empleo de cocaína intranasal se asocia a importantes entidades clínicas cardiovasculares, la mayoría de ellas graves. Se aconseja la evaluación de los pacientes en emergencia, incluyendo una anamnesis completa dirigida a la evaluación del consumo de sustancias ilícitas.

  10. A study on beverage MNCs’ entry mode decisions and determinant factors in internationalization in China: Case studies of Coca-Cola and Red bull

    OpenAIRE

    Tonsuwan, Pantitra

    2015-01-01

    The economic reform and liberalized government regulations toward business operations in 1980s make China a new target of international investments by multinational corporations (MNCs). How to enter this growth market and what entry mode should be implemented remain inconclusive. This paper analyses how two beverage companies- Coca-Cola and Red Bull that are operating in China, evaluate the influences and implications of the factors on their entry mode decisions since they initially came to C...

  11. Prenatal dietary load of Maillard reaction products combined with postnatal Coca-Cola drinking affects metabolic status of female Wistar rats

    OpenAIRE

    Gurecká, Radana; Koborová, Ivana; Janšáková, Katarína; Tábi, Tamás; Szökő, Éva; Somoza, Veronika; Šebeková, Katarína; Celec, Peter

    2015-01-01

    Aim To assess the impact of prenatal exposure to Maillard reaction products (MRPs) -rich diet and postnatal Coca- Cola consumption on metabolic status of female rats. Diet rich in MRPs and consumption of saccharose/fructose sweetened soft drinks is presumed to impose increased risk of development of cardiometabolic afflictions, such as obesity or insulin resistance. Methods At the first day of pregnancy, 9 female Wistar rats were randomized into two groups, pair-fed ei...

  12. Neuromarketing: diferencias en los niveles de atención y emoción entre hombres y mujeres respecto a Pepsi y Coca-cola

    OpenAIRE

    Pelayo García, Alejandra

    2017-01-01

    En este trabajo se desarrollan las diferencias existentes en los niveles de atención en hombres y mujeres tras haber sido expuestos a dos anuncios de Coca-cola y dos anuncios de Pepsi respectivamente. La medición fue posible gracias a la utilización del dispositivo sociograph, que nos proporcionaba datos cuantitativos, y a las encuestas pre y post visualización que nos proporcional datos cualitativos. Grado en Publicidad y Relaciones Públicas

  13. “Eu odeio Coca-Cola”: uma análise netnográfica sobre o discurso antimarca da comunidade virtual do orkut

    OpenAIRE

    Abdalla, Márcio Moutinho; Universidade Federal Fluminense; Bravo, Igor Garcia; Universidade Federal Fluminense

    2011-01-01

    It is evident broad organizational concerns regarding the management and maintenance of their brands. Retaliatory and repudiation action against product and services brands are shown as imposing barriers to be implemented by organizations. Thus, this study aims to deepen understanding of the subject by analyzing the speech of members of the virtual community antibrand "eu odeio coca-cola (I hate Coke)" in Orkut social network, besides seeking the motivations that led these members to express...

  14. Vliv sociálních sítí na marketingové strategie společnosti Coca Cola v kategorii FMCG

    OpenAIRE

    Nguyen Minh, Tuan

    2017-01-01

    The thesis analyses the possible utilizations of social networks by the companies in connection with periodic supply of new technology that faciliates communication between marketters and the target groups as well as communication between the users alone. The theoretical section summarizes actual trends of social networks world-wide. The thesis also focuses on the trends and innovational elements of the world's most popular networks. The practical part concentrates on the company Coca Cola wh...

  15. Modelo preditivo do uso de cocaína em prisões do Estado do Rio de Janeiro Predictive model for cocaine use in prisons in Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Márcia Lazaro de Carvalho

    2005-10-01

    Full Text Available OBJETIVO: Identificar variáveis preditoras e grupos mais vulneráveis ao uso de cocaína em prisão. MÉTODOS: Foram selecionados 376 presos com história de uso de cocaína em prisão (casos e 938 presos sem história de uso de cocaína na vida (controles, que cumpriam pena no sistema penitenciário do Rio de Janeiro em 1998. A análise considerou as variáveis de exposição em três níveis de hierarquia: distal, intermediário e proximal. Na análise bivariada utilizou-se regressão logística e na multivariada, regressão hierarquizada, resultando em valores de odds ratio. RESULTADOS: As variáveis associadas ao uso de cocaína na prisão, no nível proximal, foram uso de álcool e maconha e tempo de reclusão em anos. O efeito das variáveis de vulnerabilidade social (nível distal é intermediado pelas variáveis dos níveis seguintes. Considerando apenas os níveis distal e intermediário, o uso de maconha antes de ser preso (OR=4,50; IC 95%: 3,17-6,41 e o fato de ter cometido delito para obter droga (OR=2,96; IC 95%: 1,79-4,90 são as mais fortemente associadas ao desfecho. Para cada ano a mais que se passa na prisão, a chance de usar cocaína aumenta em 13% (OR=1,13; IC 95%: 1,06-1,21. CONCLUSÕES: Considerando os níveis distal e intermediário, o uso de maconha antes da prisão e delito para obtenção de droga foram as variáveis com maior poder de predição. O modelo final revelou o uso de álcool, de maconha na prisão e o tempo de cumprimento de pena são importantes preditores do desfecho. O ambiente carcerário aparece como fator estimulante da continuidade do uso de drogas.OBJECTIVE: To identify predictors of and groups vulnerable to cocaine use in prison. METHODS: We selected 376 inmates with history of cocaine use in prison (cases and 938 inmates with no history of drug use (controls serving sentences in the Rio de Janeiro State prison system in 1998. The analysis included exposure variables divided into three

  16. Successful treatment with a combination of endoscopic injection and irrigation with coca cola for gastric bezoar-induced gastric outlet obstruction.

    Science.gov (United States)

    Lin, Chen-Sheng; Tung, Chun-Fang; Peng, Yen-Chun; Chow, Wei-Keung; Chang, Chi-Sen; Hu, Wei-Hsiung

    2008-01-01

    We report a case of gastric bezoar-induced gastric outlet obstruction that was successfully treated with a combination of endoscopic injection and irrigation with Coca Cola. A 73-year-old diabetic woman had a history of perforated peptic ulcer and had received pyloroplasty more than 20 years previously. She had been ingesting Pho Pu Zi (Cordia dichotoma Forst. f.) as an appetizer for 1 month. She presented with epigastric pain, nausea, and vomiting. Upper gastrointestinal endoscopy, performed at a local hospital, showed 2 gastric bezoars in the stomach, and 1 of them impacted at the pylorus. She was referred to our emergency department for removal of the gastric bezoars that were suspected to be causing gastric outlet obstruction. All attempts at endoscopic removal using a polypectomy snare, biopsy forceps and Dormia basket failed. We then injected Coca Cola directly into the bezoar mass, followed by irrigation with Coca Cola. Follow-up endoscopy was performed the next day, which revealed that the gastric bezoars had dissolved spontaneously.

  17. Successful Treatment with a Combination of Endoscopic Injection and Irrigation with Coca Cola for Gastric Bezoar-induced Gastric Outlet Obstruction

    Directory of Open Access Journals (Sweden)

    Chen-Sheng Lin

    2008-01-01

    Full Text Available We report a case of gastric bezoar-induced gastric outlet obstruction that was successfully treated with a combination of endoscopic injection and irrigation with Coca Cola. A 73-year-old diabetic woman had a history of perforated peptic ulcer and had received pyloroplasty more than 20 years previously. She had been ingesting Pho Pu Zi (Cordia dichotoma Forst. f. as an appetizer for 1 month. She presented with epigastric pain, nausea, and vomiting. Upper gastrointestinal endoscopy, performed at a local hospital, showed 2 gastric bezoars in the stomach, and 1 of them impacted at the pylorus. She was referred to our emergency department for removal of the gastric bezoars that were suspected to be causing gastric outlet obstruction. All attempts at endoscopic removal using a polypectomy snare, biopsy forceps and Dormia basket failed. We then injected Coca Cola directly into the bezoar mass, followed by irrigation with Coca Cola. Follow-up endoscopy was performed the next day, which revealed that the gastric bezoars had dissolved spontaneously.

  18. La experiencia enlatada del compartir. Análisis de la regulación de las sensaciones en “Comparte tu Coca-Cola con” en las campañas de Coca-Cola 2014-2015

    Directory of Open Access Journals (Sweden)

    Eliana Isabel Abraham

    2015-09-01

    Full Text Available El siguiente artículo pretende analizar los procesos de regulación de las sensaciones que construye el capitalismo sobre la experiencia social del “compartir/compartir con otros” en las campañas de Coca-Cola 2014-2015. Se tomara como horizonte epistemológico las contribuciones de una sociología de las emociones para desentramar los operativos ideológicos que subyacen en el montaje de las distintas instantáneas de consumo en torno a la campaña. Será pertinente para este caso, realizar una genealogía de las interpelaciones a lo sensible que construyó la empresa desde su llegada al país en 1942 y el especial tratamiento que reside en esta última apuesta del monopolio de la bebida al asalto de las experiencias. Por último, siguiendo el dictum benjaminiano, algunas imágenes publicitarias de la campaña que circulan en redes sociales para pensar el escenario mediático que refuerza los procesos de regulación a lo sensible.

  19. RO unit for canned coffee drink processing line. Shipped to Tone Coca-Cola Bottling Co. Ltd., Ibaraki plant; Coffee line yo RO sochi. Tone Coca-Cola Bottling (kabu) Ibaraki kojo nonyu

    Energy Technology Data Exchange (ETDEWEB)

    Nakajima, K. [Ebara Corp., Tokyo (Japan)

    1996-01-20

    The paper introduces an RO unit (reverse osmotic membrane equipment) for producing water holding for the canned coffee drink processing line introduced to the Ibaraki plant of Tone Coca-Cola Bottling Co. The unit aims at reducing hardness components from city water and producing water holding for the coffee drink processing line. The capacity of the unit is 25m{sup 3}/h and the recovery rate is 80%. The unit is composed of a sand filter, an heat exchanger, a pre-filter, RO modules, a treated water tank, chemicals storage tanks, and an RO cleaning unit, which are all for pretreatment. The treated water, into which chlorine is injected, is sent through the existing activated carbon tower and micro filter to the processing line. The RO unit can remove at the same time ion and trihalomethane, pathogens, organic matters which are substances other than hardness components. The continued water bottling is possible with no need for the usual reproduction process, and the maintenance is easy. Because of the high hardness of the supplied raw water, acid is injected at the primary side of the unit for pH regulation to prevent scale deposition in the RO modules. The quality of the treated water well met the specifications. 2 figs., 2 tabs.

  20. Palavra de coca e de tabaco como "conhecimento tradicional": cultura, política e desenvolvimento entre os uitoto-murui do rio Caraparaná (CO The word of coca and tobacco as 'traditional knowledge': culture, politics and development among the uitoto-murui of the Cara Paraná River (Colombia

    Directory of Open Access Journals (Sweden)

    Edmundo Pereira

    2011-04-01

    Full Text Available Entre 2000-2001, um debate mobilizou os aldeamentos uitoto-murui do rio Caraparaná tendo como tema a noção de "desenvolvimento". Alguns deles sediaram reuniões entre indígenas (locais e de órgãos de representação política nacional e não indígenas (técnicos de Estado, de ONGs e militares na produção de "diagnósticos" e "projetos". Nesse contexto, o aldeamento de San Rafael, em articulação entre seu cacique, Don Ángel Ortiz, e o cabildo local, propõe um projeto baseado nos "conhecimentos" das rodas noturnas de diálogo e consumo ritual da coca (Erythroxylon coca var. ipadu e do tabaco (Nicotiana tabacum, no conjunto de conhecimentos materiais, simbólicos e ético-morais chamado de "Palavra de Coca e de Tabaco" (jiibina uai diona uai. Este conjunto de "conhecimentos" (do mítico-cosmológico ao médico-terapêutico e as formas de governança é o resultado das articulações socioculturais vividas pelos grupos indígenas que habitam o interflúvio dos rios Caquetá-Putumayo (que têm a coca e o tabaco como epicentros simbólicos, em especial após a década de 1930, com o fim da escravidão caucheira e do conflito Peru-Colômbia. No calor dos debates, a noção de "desenvolvimento" ganha, então, contornos "indígenas", passando a ser lida e articulada a partir dos "usos e costumes" locais, como demanda a Constituição de 1991. Do mesmo modo, diante das demandas da arena do desenvolvimento, um perfil discreto e acabado do que seja a Palavra de Coca e de Tabaco é também apresentado.Throughout 2000 and 2001 the Uitoto-Murui communities of the Cara Paraná River were mobilized by a debate on the notion of 'development.' Meetings were held between the indigenous population (including both local villagers and representatives of national organizations and the non-indigenous population (government officials, NGOs and the military to discuss the theme with the aim of producing 'diagnoses' and 'projects.' As part of this context, the

  1. Retardo del crecimiento intrauterino asociado con el consumo de pasta básica de cocaína por mujeres gestantes de Bogotá, D.C., Colombia

    Directory of Open Access Journals (Sweden)

    Oscar Ramírez

    2000-12-01

    Full Text Available El objetivo de este estudio fue identificar una posible asociación entre el consumo de pasta ásica de cocaína o 'basuco' entre mujeres embarazadas y el crecimiento intrauterino de sus productos vivos en dos hospitales de tercer nivel en Bogotá, Colombia. Con un diseño de cohorte retrospectiva, se encuestaron 1.878 mujeres en el puerperio mediato para indagar, entre otras variables, la historia sobre el consumo de drogas ilicitas. Tanto a las madres como a sus recién nacidos se les realizaron mediciones antropométricas estandarizadas. Se comparó la prevalencia de bajo peso al nacer (BPN, parto prematuro (PP y retardo del crecimiento intrauterino (RCIU con la historia de consumo de drogas ilicitas durante el embarazo por medio de modelos de regresión lineal múltiple y regresión logística múltiple, para ajustar el efecto de posibles confusores como edad materna, estado nutricional y patologias maternas, nivel socioeconómico, escolaridad y tabaquismo, entre otros. Los resultados mostraron que una de cada 189 mujeres consumió sustancias ilegales durante el embarazo, comúnmente Cannabis safiva o pasta básica de cocaina. Las consumidoras de ostos productos tipicamente tenían menor escolaridad, eran de nivel socioeconomico más bajo. eran más delgadas, con una historia de control prenatal inadecuado, primigestantes o multigestantes y, con frecuencia, también fumaban tabaco y bebían alcohol. Se halló una asociación entre el consumo de las sustancias ilegales con RCIU (cociente de suertes de prevalencias de 5.24, IC95%: 1,3-21.0, y un déficit de 0.7 desvios estándares del peso para la edad gestacional (p=0.03. Además, se encontró un cociente de suertes ajustado de 7,78 con IC95%: 1,O-62, entre el consumo de pasta básica de cocaina y RCIU. Aunque es probable que a través de entrevistas se subestime la prevalencia de consumo de drogas y a pesar del limitado poder del estudio, éste fue capaz de identificar un efecto importante

  2. A influência da marca Coca Cola na atratividade e manutenção dos funcionários em uma afiliada no Rio Grande Do Sul

    Directory of Open Access Journals (Sweden)

    Carla Cavalheiro Lima

    2014-01-01

    Full Text Available O estudo analisou a influência da marca Coca-Cola na atratividade e manutenção de funcionários em uma empresa afiliada de uma franqueada da The Coca-Cola Company, denominada CVI Refrigerantes Ltda., identificando o nível de conhecimento prévio dos colaboradores da empresa sobre a mesma, verificando os atributos relacionados à marca na visão destes e diagnosticando fatores considerados decisivos no momento da escolha da empresa como empregadora. Foi realizada análise documental e de entrevistas  semiestruturadas com funcionários. Constata-se que a imagem e o nome da marca Coca-Cola constituem, para os funcionários, fortes atrativos, além dos benefícios e oportunidades de crescimento oferecidos.

  3. A influência da marca Coca Cola na atratividade e manutenção dos funcionários em uma afiliada no Rio Grande Do Sul

    Directory of Open Access Journals (Sweden)

    Christine da Silva Schröeder

    2014-05-01

    Full Text Available O estudo analisou a influência da marca Coca-Cola na atratividade e manutenção de funcionários em uma empresa afiliada de uma franqueada da The Coca-Cola Company, denominada CVI Refrigerantes Ltda., identificando o nível de conhecimento prévio dos colaboradores da empresa sobre a mesma, verificando os atributos relacionados à marca na visão destes e diagnosticando fatores considerados decisivos no momento da escolha da empresa como empregadora. Foi realizada análise documental e de entrevistas semiestruturadas com funcionários. Constata-se que a imagem e o nome da marca Coca-Cola constituem, para os funcionários, fortes atrativos, além dos benefícios e oportunidades de crescimento oferecidos.

  4. Estereótipos de gênero no cuidado psicossocial das usuárias de cocaína e crack

    Directory of Open Access Journals (Sweden)

    Érika Barbosa de Oliveira Silva

    2018-05-01

    Full Text Available A presente pesquisa analisou as concepções dos profissionais de saúde sobre as mulheres usuárias de cocaína e crack em processo de cuidado psicossocial baseando-se na perspectiva de gênero. Para tal fim, foram entrevistados 17 profissionais de saúde e procedidas observações sistemáticas nos espaços de cuidado coletivo em um Centro de Atenção Psicossocial para álcool e drogas da Região Metropolitana do Rio de Janeiro, Brasil. A análise das entrevistas e diários de campo foi realizada por meio do método hermenêutico-dialético, que revelou três categorias: a fragilidade como atributo constitutivo da condição feminina; a dependência afetiva feminina relacionada com o uso de cocaína e crack; e os estereótipos de gênero no cuidado psicossocial. Os profissionais de saúde expressam a visão tradicional da mulher heterossexual, dócil e maternal, e reproduzem concepções estereotipadas ao considerar as usuárias de cocaína e crack como pessoas sensíveis, frágeis, dependentes afetivamente dos homens e mais envolvidas com o lar e a família. Esses profissionais carecem de uma compreensão mais elaborada sobre as questões de gênero no processo saúde/doença mental, a fim de possibilitar a superação do senso comum e da práxis de cuidado reducionista.

  5. A publicidade da Coca-Cola “Happiness Factory” e o imaginário do sistema produtivo na sociedade de consumo

    Directory of Open Access Journals (Sweden)

    João Carrascoza

    2008-09-01

    Full Text Available O artigo propõe a reflexão sobre o universo simbólico da marca Coca-Cola com base no comercial “Happiness Factory” (“Fábrica de Felicidade”, 2006, em que a esfera produtiva da corporação é recuperada como espetáculo, como apoteose, para servir ao imaginário do consumo. Trata-se de estudo preliminar sobre os processos simbólicos de reconstrução, de esvaziamento, de harmonização das tensões e dialéticas que envolvem o mundo do trabalho, para servir à publicidade da marca – esta entendida como ente social, mediador da negociação simbólica entre anunciantes e consumidores. A metodologia de análise é baseada no quadro teórico da análise do discurso de linha francesa e de conceitos- chave da obra de Mikhail Bakhtin, entre outros autores. Palavras-chave: Publicidade; consumo simbólico; trabalho.ABSTRACT This article presents a reflection on the symbolic universe of the Coca-Cola brand based on the comercial “Happiness Factory” (2006, in which the productive sphere of the corporation is transformed and presented as a spectacle, as an apotheosis in order to meet the purposes of consumption imaginary. This is a preliminary study on the symbolic processes of reconstruction, of emptying and of the harmonization of tensions and dialectics which involve the world of labour in order to meet the requirements of the publicity of the Coca-Cola brand – which is understood as a social being, mediator of the symbolic negotiation between advertisers and consumers. Our methodology of analysis is based on the theoretical framework of the French line of discourse analysis and key concepts of Mikhail Bakhtin, among other authors. Keywords: Advertising; symbolic consumption; brands.

  6. “Viver positivamente”: as lições ensinadas por peças publicitárias da Coca-Cola Company

    Directory of Open Access Journals (Sweden)

    Daniela Ripoll

    2014-08-01

    Full Text Available Analisa-se a campanha publicitária da Coca-Cola Company Brasil, “Viva positivamente!”. A partir dos Estudos Culturais, dos Estudos de Mídia e das discussões pós-modernas acerca do consumo do corpo e de determinados estilos de vida na mídia, discute-se o crescente movimento de “redenção” ou, ainda, de “absolvição” do consumo, construído pedagógica e culturalmente como algo positivo e relacionado à melhora do corpo e da qualidade de vida dos sujeitos na contemporaneidade.

  7. Estrategia de comunicación de mercadeo con Énfasis en la plataforma digital -redes sociales y geolocalización- para Coca-Cola Zero

    OpenAIRE

    Lara Cascante, Mariela

    2012-01-01

    Tesis de maestría -- Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Administración y Dirección de Empresas con énfasis en Mercadeo y Ventas, 2012 El proyecto, desarrollado a lo largo de este documento, incluye la preparación y descripción de una estrategia de comunicación de mercadeo, que tiene un enfoque en el uso de herramientas digitales, como redes sociales y geolocalización, para fortalecer la marca de bebida gaseosa Coca-Cola Ze...

  8. Comportamiento de la empresa criminal productora de cocaína en Antioquia, desde el análisis econométrico espacial

    OpenAIRE

    Sarmiento Reyes, Carlos Arturo; Arias Cuéllar, Juan Carlos

    2015-01-01

    El enfoque principal del presente estudio se basa en el análisis de la cadena productiva de cocaína en el Departamento de Antioquia (Colombia), particularmente en sus 125 municipios durante el periodo 2010-2015 -- Se utiliza el análisis econométrico e inferencia de datos espaciales que establecen condiciones de atipicidad, adyacencia y autocorrelación que permiten asociar el comportamiento de estas variables como una empresa criminal totalmente estructurada en función de capital y trabajo -- ...

  9. Plan estratégico de marketing de nueva línea de jugos premium para the Coca-Cola Company

    OpenAIRE

    Carbonel, Magaly; Ríos, Nicole; Taborga, Marcelo; Victorero, Natalia

    2017-01-01

    La alimentación saludable está cambiando los patrones de consumo de la sociedad, los consumidores están eligiendo productos bajos en grasas, sin preservantes u otros componentes dañinos a la salud. La categoría de jugos no es ajena a esta realidad, de acuerdo a las tendencias globales, regionales y locales, se ha evaluado la posibilidad de incorporar un jugo Premium RTD (100% jugo listo para consumir) al portafolio de The Coca-Cola Company en Lima Metropolitana. El presente Pla...

  10. Desarrollo y fabricación de una herramienta para la erradicación manual de cultivos de mata de coca

    OpenAIRE

    Vasco Ceballos, Camilo Andrés; Vásquez Gómez, David

    2008-01-01

    En Colombia se viene desarrollando actualmente la erradicación de cultivos ilícitos manualmente, tal y como se hizo en otros países -- Se opto por este proceso ya que se ha demostrado que con el herbicida Glifosato no solo mueren las matas de coca, amapola y marihuana, sino que también lo hacen especies nativas, generando un enorme impacto ambiental al ecosistema -- El proceso ha demostrado ser muy efectivo, además de todo lo que conlleva su realización; familias cobijadas con sustitución de ...

  11. O uso do diagrama comparativo como ferramenta de abordagem sistêmica na gestão de design das marcas coca cola e Pepsi

    OpenAIRE

    Sá, Túlio Henrique Mandolesi; Universidade Federal de Santa Catarina - UFSC; Merino, Giselle Schmidt Díaz; Universidade Federal de Santa Catarina/UFSC; Figueiredo, Luiz Fernando Gonçalves de; UFSC - Universidade Federal de Santa Catarina; Souza, Richard Perassi Luiz de; UFSC - Universidade Federal de Santa Catarina

    2014-01-01

    This article presents the product mix that brands Coca-Cola and PepsiCo. operates in Brazil. Through a descriptive and exploratory research and based on the Kotler’s criteria for classifying products, will be presented in a diagram, a visual representation of the performance of these brands. The goal is to identify that they work their management in order to expand their business presence to strengthen they position in the mind of their consumers. Este artigo apresenta o mix de produtos co...

  12. [Ecological studies on mollusk populations of medical and veterinary relevance existing in La Coca farm].

    Science.gov (United States)

    Wong Sarmiento, Lin; Vázquez Perera, Antonio A; Quesada Martínez, Maritza; Sánchez Noda, Jorge; Hevia Jiménez, Yosvania; Fuentes Leyva, Joaquín; Ramos Pérez, Ramón

    2010-01-01

    ecological studies were carried out on mollusk populations of medical and veterinary importance with emphasis on Fasciola hepatica intermediary hosts species. to determine the relative abundance of populations and the possible use of some species as biological control agents against F. hepatica intermediary hosts. a total of 13 freshwater bodies were sampled during March and November, 2008 using Capture by effort unit method to capture the mollusks thirteen mollusk species (12 gastropods and 1 bivalve) were found after sampling. The relative abundance of species varied in different types of habitat. The intermediary host species of fascioliasis were dominant in two sites. Fossaria cubensis was dominant in Canal de la Entrada despite the presence of Melanoides tuberculata. The specie Pseudosuccinea columella was more abundant in Los Mangos. In La Presa del Matadero y Las Palmas despite the presence of these species, the prevailing ones were Physa acuta and some planorbids. the sites where intermediary hosts of Fasciola hepatica predominated were identified through data on the distribution and relative abundance. In some sites Melanoides tuberculata was present and acted as a biological control agent but it did not in others. Therefore, an evaluation on using a different thiarid would be useful to control these species.

  13. Réflexion sur le développement alternatif à la culture de la coca en Amérique andine

    Directory of Open Access Journals (Sweden)

    Follin Jean-Claude

    2001-11-01

    Full Text Available Dans les années 1965-1975, on observe un développement très important des cultures illicites et de la consommation de drogues, qui s’accentue encore dans la décennie suivante. Ce développement est concomitant à deux phénomènes mondiaux indépendants : d’une part, l’ouverture des agricultures du Sud à l’économie de marché et, d’autre part, des changements culturels profonds dans les pays du Nord, avec les premières manifestations de dérégulation sociale. Les premières actions internationales, dans le domaine de la réduction de l’offre, pour le contrôle de la culture des plantes productrices de drogues ont commencé au milieu des années 70 en Asie sur la culture du pavot (au travers du Pnucid - programme des Nations unies pour le contrôle international des drogues ; elles se sont ensuite développées en Amérique latine sur la culture de la coca (création de la Comisión interamericana para el control del abuso de drogas - Cicad, en 1986, puis dans le bassin méditerranéen au début des années 90 sur la culture du chanvre (programmes UE/MED. Les premières années, cette lutte s’est opérée sous le concept de cultures de substitution (ou cultures alternatives : les parcelles de culture illicites étaient arrachées et remplacées par d’autres productions. L’analyse des échecs répétés de ce type d’intervention a montré que les régions productrices étaient presque toujours des régions marginalisées d’un point de vue socio-économique et que la lutte contre les cultures illicites n’était pas uniquement une affaire de développement de nouvelles cultures. Il était, en fait, nécessaire de créer les conditions d’une nouvelle économie agricole. Ainsi, le concept de développement alternatif a peu à peu émergé pour aboutir aux grands principes de base énoncés, en 33 points, lors de l’assemblée générale des Nations unies du 8 septembre 1998 1.

  14. El caso Coca Nasa : análisis jurídico de la política del Estado colombiano en materia de comercialización de alimentos y bebidas derivados de hoja de coca producidos por comunidades indígenas

    OpenAIRE

    Ceballos Bedoya, Nicolás

    2008-01-01

    El presente trabajo surgió en el marco de mi práctica en el grupo de investigación “Derechos Fundamentales y Diversidad cultural”; en ese entonces, me enteré de la prohibición a los productos de hoja de coca que comercializa la comunidad nasa de Calderas en el Cauca, que se originó una vez el INVIMA emitió una circular restringiendo su venta a los territorios indígenas. Este caso particular fue de nuestro interés ya que permitía analizar múltiples problemas atinentes al reconocimiento de la d...

  15. O percurso dos gêneros do discurso publicitário: considerações sobre as propagandas da Coca-cola

    OpenAIRE

    Campos-Toscano, Ana Lúcia Furquim [UNESP

    2008-01-01

    Com base nas reflexões do Círculo de Mikhail Bakhtin sobre gêneros do discurso e dialogismo e com a contribuição de outros estudiosos da linguagem e do discurso, além da utilização de referencial teórico das áreas de Comunicação Social, História e Sociologia, este trabalho tem como objetivo principal entender o percurso dos gêneros do discurso publicitário por meio da análise das propagandas da Coca-Cola e de seus contradiscursos. O corpus desta pesquisa constitui-se de propagandas impressas,...

  16. Efectos de la cocaína y del tolueno sobre la neurogénesis en el hipocampo de rata

    OpenAIRE

    Domínguez Escribà, Laura

    2009-01-01

    En el presente proyecto se estudió el efecto de dos drogas adictivas, el tolueno y la cocaína, sobre la neurogénesis hipocámpica. Los experimentos diseñados para ambas drogas, abordaron el estudio de la neurogénesis, a través de la medida de proliferación, supervivencia, diferenciación y migración. Además se analizó el efecto ultraestructural que ambas drogas causan sobre el giro dentado. De forma más exhaustiva, se estudió el efecto producido por una administración crónica ...

  17. El proyecto hidroeléctrico Coca Codo Sinclair y la gobernanza energética en la Amazonía ecuatoriana

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    Victor López

    2013-10-01

    Full Text Available Las condiciones en las que el Estado impulsa el cambio de la matriz energética, configuran problemas de gobernanza y retos para una gestión de energías renovables en la Amazonía, acorde con la Constitución y la planificación estatal del desarrollo. Coca Codo Sinclair (CCS es el mayor proyecto hidroeléctrico en implementación y apuntala las políticas de soberanía y eficiencia energética del gobierno, sin que se evidencien criterios de gestión integrada del recurso hídrico y equidad regional para las poblaciones locales.

  18. O episódio de Freud com a cocaína: o médico e o monstro

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    Decio Gurfinkel

    2008-09-01

    Full Text Available O objetivo do trabalho é uma avaliação dos possíveis "restos" que o episódio de Freud com a cocaína tenha deixado para a criação da psicanálise, realizada através do reexame retrospectivo, crítico e analítico desse episódio. O resultado desta avaliação pôs em destaque quatro elementos: o surgimento de um Freud psiquiatra e farmacologista e o progressivo abandono desta via; o surgimento da adicção como objeto de investigação; o modelo da auto-administração como método de pesquisa; e a crença e abandono subseqüente de um projeto de "cura mágica".

  19. Profile of cocaine and crack users in Brazil Perfil dos usuários de cocaína e crack no Brasil

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    Lígia Bonacim Duailibi

    2008-01-01

    Full Text Available This article aims to systematize the profile of cocaine and crack users in Brazil. The study adopted a literature review of the MEDLINE, LILACS, Cochrane Library databases and CAPES thesis/dissertation database. Data were grouped in thematic categories: national household surveys, surveys of specific population groups, profile of patients that seek treatment, and mortality and morbidity. Within each category the principal findings from the Brazilian literature were described and then discussed. The article concludes that the information on cocaine and crack consumption in Brazil is still incipient, but that the scientific community can already draw on a relevant theoretical corpus that can be used to update current public policies on this issue.Este artigo tem como objetivo sintetizar o perfil dos usuários de cocaína e crack no Brasil. Foi construído por meio de revisão da literatura com base em dados (MEDLINE, LILACS e Biblioteca Cochrane e no banco de teses da CAPES. Os dados foram agrupados em categorias temáticas, quais sejam: levantamentos domiciliares nacionais, populações específicas, perfil dos pacientes que procuram tratamento, mortalidade e morbidade. Dentro de cada categoria os principais achados da literatura nacional foram descritos e posteriormente discutidos. O artigo conclui que informações relacionadas ao consumo de cocaína e crack no Brasil ainda são incipientes, mas já temos à disposição da comunidade científica um conjunto teórico relevante que pode ser utilizado visando à atualização das atuais políticas públicas referentes a este tema.

  20. La «i-Generación» y su interacción en las redes sociales. Análisis de Coca-Cola en Tuenti

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    Carmen Marta Lazo

    2013-03-01

    Full Text Available Los adolescentes y jóvenes utilizan cada vez más las redes sociales como medio para interactuar y participar en la construcción de un discurso múltiple. Las empresas aprovechan las opciones de relación directa con los seguidores en las redes y utilizan estas estructuras virtuales para acercarse a su «target». El objeto de este artículo es estudiar, mediante una metodología empírica y observacional, cómo construye «Coca-Cola» su imagen de marca en «Tuenti», la red más seguida por este sector del público. Entre otros aspectos, observaremos de qué modo interviene la marca y cómo los seguidores; cuáles son los temas que se introducen en las entradas y a través de qué tipo de formatos. Como conclusión, advertimos que el interés de la marca de dejar libertad de expresión a los seguidores es solo una estrategia, en realidad las entradas de «Coca-Cola» son muy escasas pero todas ellas tienen un elevado efecto «gancho», pues con un lenguaje que interpela al usuario para que se active y retome su discurso de manera dirigida. Además, no existe ningún tipo de mecanismo diferenciador entre la información, el entretenimiento y la publicidad, lo que, unido a la exposición continuada a impactos publicitarios a través de diferentes formatos, nos lleva a proponer la necesidad de una educación mediática para fomentar el uso responsable y crítico de las redes sociales por parte de los jóvenes.

  1. Investigación de cocaína y marihuana en meconio de neonatos atendidos en un hospital público: Primera experiencia realizada en la ciudad Córdoba, Argentina Screening of cocaine and marijuana in meconium of newborns from a public hospital of city of Córdoba, Argentina

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    Andrés Suárez

    2009-12-01

    Full Text Available Se investigaron cocaína y marihuana en meconio de neonatos nacidos en la Maternidad Provincial de la Ciudad de Córdoba y se relacionaron los resultados con las semanas de gestación y los pesos al nacer. Las determinaciones se realizaron utilizando inmunoensayo y cromatografía gaseosa-espectrometría de masas. Se analizaron 48 muestras de meconio recolectadas durante un año (2007-2008. De los 48 meconios analizados, 17 correspondieron a neonatos masculinos y 31 a neonatos femeninos. Se procesaron en paralelo 15 muestras de meconio como controles normales (niños no expuestos a drogas seleccionados por historia clínica y controles prenatales. De las 48 muestras de meconio 13 fueron positivas para cocaína y/o marihuana. El peso y las semanas de gestación de los neonatos cuyas muestras fueron positivas se compararon frente a un grupo control normal, hallándose mayores diferencias estadísticamente significativas (α=0,05 - pWe investigated cocaine and marijuana in meconium of newborns attended at the Hospital Materno Provincial of Córdoba City and the results were correlated with birthweight and weeks of pregnancy. The samples were analyzed using immunoassay (FPIA and gas chromatography-mass spectrometry (GC-MS for confirmation. Forty eight samples of meconium were collected during one year period (2007-2008. Of the 48 samples screened, 17 correspond to masculine sex and 31 to feminine. Fifteen samples of meconium from normal newborns (newborns not exposed to drugs selected by maternal self report, pregnancy controls were processed as control group. The results obtained in 48 samples of meconium showed 13 cases tested positive for cocaine and/or marijuana. Birth weight and weeks of gestation of newborn with positive sample results were compared with a control group. A statistically significant difference (α= 0.05 - p<0.0001 was found in relation to birth weight. Although these results arise from a small number of samples, these data have

  2. Intoxicación aguda por cocaína en un lactante no asociada a lactancia materna: A propósito de un caso clínico

    OpenAIRE

    Decia1, Mónica; Pan, Melina; Telechea, Héctor; Laborde, Amalia; Menchaca, Amanda

    2015-01-01

    La intoxicación aguda por cocaína es infrecuente en lactantes y niños. Las formas más frecuentes de presentación clínica son las convulsiones tónico-clónicas en apirexia, alteraciones motoras y la excitación psicomotriz. Se presenta el caso de un lactante de 1 mes que ingresó a la Unidad de Cuidados Intensivos de Niños del Centro Hospitalario Pereira Rossell por una intoxicación aguda por cocaína. El cuadro clínico consistió en manifestaciones secundarias a un estado hiperadrenérgico generali...

  3. Complicações cardiovasculares em usuário de cocaína: relato de caso Cardiovascular complications related to cocaine use: case report

    Directory of Open Access Journals (Sweden)

    Fernanda Martins Gazoni

    2006-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A cocaína é uma droga ilícita amplamente utilizada e o seu uso tem sido associado a efeitos decorrentes da toxicidade aguda e crônica em praticamente todos os órgãos, particularmente no sistema cardiovascular. Este artigo visou descrever um caso de cardiomiopatia em paciente jovem usuário crônico de cocaína. RELATO DO CASO: Paciente do sexo masculino, 19 anos, usuário de cocaína por inalação e crack desde os 15 anos de idade. Foi internado em fevereiro de 2006 devido a dispnéia progressiva aos mínimos esforços e expectoração sanguinolenta. Ao exame físico apresentava edema nos membros inferiores, estase jugular e dispnéia em repouso. Foram observados no ecocardiograma: dilatação das quatro câmaras cardíacas, com hipocinesia difusa de ventrículo esquerdo (VE, trombo mural em VE de 17 mm e fração de ejeção de 12%. Realizada broncoscopia pulmonar que identificou sangramento em língula ativo, tratado com embolização. Após 48h do procedimento, o paciente manteve-se assintomático e sem expectoração sanguinolenta. Iniciado tratamento antitrombótico com warfarina e enoxaparina. A cineangiocoronariografia não evidenciou lesões obstrutivas e o paciente recebeu alta após melhora clínica. Re-internado em julho de 2006 com dor precordial de forte intensidade e dispnéia de repouso. Nova cineangiocoronariografia evidenciou oclusão de terço médio da artéria descendente anterior. CONCLUSÕES: Os efeitos agudos da cocaína freqüentemente motivam atendimento de emergência. Já as suas manifestações crônicas, como as doenças cardiovasculares, podem produzir alterações de difícil correlação futura ao seu consumo prévio. O uso prolongado da cocaína está relacionado à alteração da função sistólica ventricular esquerda por hipertrofia ou dilatação miocárdica, aterosclerose, disritmias cardíacas, apoptose de cardiomiócitos e lesão simpática.BACKGROUND AND OBJECTIVES

  4. OCIAL CONSEQUENCES OF THE CULTIVATION OF COCA IN AFROCOLOMBIAN COMMUNITIES IN CAQUETÁ: ANALYSIS OF THE RELATIONSHIP AMONG THE ILLICIT ECONOMY, THE TRADITIONAL FARMING PRACTICES, AND THEIR ROLE IN FOOD SECURITY. CONSECUENCIAS SOCIALES DEL CULTIVO DE LA COCA EN COMUNIDADES AFROCOLOMBIANAS DEL CAQUETÁ: ANÁLISIS DE LA RELACIÓN ENTRE LA ECONOMÍA ILÍCITA, LAS PRÁCTICAS CAMPESINAS TRADICIONALES Y SU PAPEL EN LA SEGURIDAD ALIMENTARIA

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    Lorena Carrillo González.

    2014-06-01

    Full Text Available This article presents the main results of an investigation into the consequences of the adoption of the cultivation of coca, the productive logic of the illicit economy, and anti-drug policies of the Colombian State have meant for the safety and food sovereignty of Afrocolombian communities in the State of Caquetá. The work was based on extensive field work carried out in the rural area of inspection of Rionegro, Municipality of Puerto Rico. The text examines the role played by the regional history, the social and economic context in the reasons that help to explain the reason for the presence of coca. It gives an account of the main features of the mode of family production that characterizes the coca in the region and finally, and it shows the impact that the counter-narcotics policy has on food security of the communities in the study area. In order to provide elements for the discussion of the alternatives to the cultivation of coca, the article shows how the production practices in the region, both legal and illegal, do not pass through the construction of a project of food sovereignty and fail to meet the basics of food safety. RESUMEN: El artículo expone los principales resultados de una investigación sobre las consecuencias que la adopción del cultivo de coca, las lógicas productivas de la economía ilícita, y las políticas antinarcóticos del estado Colombiano han significado para la seguridad y soberanía alimentaria de comunidades afrocolombianas en el departamento del Caquetá. El trabajo se sustentó en un extenso trabajo de campo realizado en la zona rural de la inspección de Rionegro, municipio de puerto Rico. En el texto se analiza el papel que juegan la historia regional, el contexto social y económico en las razones que permiten explicar el por qué de la presencia de la coca. Se da cuenta de las principales características de la modalidad de producción familiar que caracteriza la coca en la región y finalmente, y

  5. EVALUASI PENERAPAN ABg (AKTIF BERBAGI SISTEM SEBAGAI UPAYA MENGURANGI ANGKA KECELAKAAN KERJA DI PT. COCA-COLA AMATIL INDONESIA CENTRAL JAVA

    Directory of Open Access Journals (Sweden)

    Asep Alvan

    2016-01-01

    Full Text Available PT. Coca-Cola Amatil Indonesia Central Java (CCAI-CJ pada tahun 2013 telah menerapkan program ABg (Aktif Berbagi Sistem, pada tahun tersebut terdapat peningkatan kasus kecelakaan kerja di area kerja dari tahun sebelumnya sebanyak 2 kasus. Tujuan penelitian ini adalah untuk mengetahui gambaran evaluasi dan rekomendasi dari kendala-kendala dalam penerapan ABg Sistem sebagai upaya mengurangi angka kecelakaan kerja di PT. CCAI-CJ. Jenis penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan etnografi. Teknik pengambilan sumber informasi yang digunakan adalah teknik snowball sampling, jumlah informan awal yaitu dua orang. Hasil penelitian didapatkan masih terdapat kendala dalam penerapan ABg Sistem yaitu: pelaksanaan pengawasan Keselamatan dan Kesehatan Kerja (K3 yang belum berjalan konsisten. Konsistensi penerapan peraturan dan prosedur K3 yang belum optimal serta adanya sanksi yang tidak sesuai dengan prosedur penerapan ABg Sistem. Kurangnya komunikasi antara manajemen dengan pekerja dan kurangnya pemahaman pekerja tentang informasi K3. Kurangnya keterlibatan pekerja dalam pelaporan kejadian kecelakaan/kondisi berbahaya. Saran yang dapat diberikan yaitu: konsistensi pelaksanaan pengawasan K3 sesuai prosedur, sanksi yang diberikan lebih baik berupa arahan bagi pekerja untuk dapat bekerja lebih aman, melakukan komunikasi kepada pekerja sesuai dengan prosedur komunikasi internal, diadakan peningkatan kompetensi melalui pelatihan awareness K3, serta dilakukan pelatihan mengenai prosedur pelaporan kecelakaan/kondisi berbahaya kepada pekerja. PT. Coca-Cola Amatil Indonesia Central Java (CCAI-CJ in 2013 has implemented ABg (Aktif Berbagi system program, there are two accident cases increase in 2013 at the working areas. The purpose of this study is to describe the evaluation and recommendation of the constraints in the implementation of ABg System as an effort to reduce the number of accidents in the workplace. This research design is a

  6. Padrão de uso de cannabis em dependentes de crack/cocaína internados para desintoxicação

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    Laura Baptista Lewgoy

    2014-08-01

    Full Text Available Introdução: O presente trabalho teve como objetivo verificar o padrão de uso de cannabis em dependentes de crack/cocaína internados para desintoxicação em uma unidade de internação especializada. Métodos: Pesquisa quantitativa com delineamento exploratório e transversal em amostra não aleatória (n=109 de dependentes de crack/cocaína segundo os critérios da Classificação Internacional de Doenças (CID-10. O protocolo de coleta foi composto por: informações sociodemográficas e descrição do padrão de uso de substâncias psicoativas, Inventário Beck de Ansiedade (BAI e Inventário Beck de Depressão (BDI. Resultados: Os participantes, com média de idade de 27,82 anos (DP=6,68; 18-49 e com 8,19 (2,56; 4-16 de anos de estudo, estavam internados há cerca de 14,81 dias (DP=11,51; 7-64. Verificou-se que a idade média de início do uso de cannabis (15,17 +-3,29 é bastante inferior à idade de início do uso de crack (22,76 +-6,28. Achados indicam que a cannabis foi a primeira droga ilícita a ser consumida pelos dependentes de crack, sendo que 96,33% desses sujeitos apresentavam dependência de cannabis. Conclusão: Foi encontrada uma correlação positiva (r=0,385 de intensidade baixa entre a idade de início de consumo de crack e de cannabis, concluindo-se que, quanto mais cedo é iniciado o uso de cannabis, mais cedo é iniciado o uso de crack.

  7. Quality of cocaine seized in 1997 in the street-drug market of São Paulo city, Brazil Qualidade da cocaína traficada em 1997 na cidade de São Paulo, Brasil

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    Débora Gonçalves de Carvalho

    2003-03-01

    carbonates and bicarbonates (19.2%; silicates (13.8%, sugars (9.59%; starch (5.6%, borate (3.8% and sulphates(2.8%. Contaminants (secondary products originated from coca paste refining or decomposition processes were not analysed.Teores de cocaína e adulterantes bem como vários diluentes foram determinados em 389 amostras de pó branco apreendidas na cidade de São Paulo, no ano de 1997. Cocaína e seus adulterantes foram analisados por cromatografia em camada delgada, cromatografia em fase gasosa (detetor de ionização de chama e cromatografia em fase gasosa acoplado a espectrometria de massa (CG/MS. Diluentes foram analisados através de "spot tests" e da cromatografia em camada delgada. Foram obtidos os seguintes resultados: em 4,4% das amostras não foram detectados cocaína e adulterantes; de todas as amostras positivas para cocaína, 14% não continham mais que 200 mg/g de pó; em 70% a pureza da cocaína variou de 201 a 550 mg/g e em 16% não foi maior que 700 mg/g. Os anestésicos locais lidocaína e procaína foram detectados em 19 amostras em concentrações que variaram de 10 a 602 mg/g de pó. Cafeína foi encontrada em duas amostras. Os principais diluentes detectados foram: carbonatos e bicarbonatos, silicatos, açúcares, amido, borato e sulfatos. Contaminantes (produtos secundários originários do refino da pasta de coca ou de processos de decomposição não foram analisados.

  8. The decision of farmers from the tropical region of Cochabamba in Bolivia to cultivate coca instead of state-recommended alternative products

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    Barrientos Juan Carlos

    2006-06-01

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    Despite national coca cultivation having been prohibited from 1973 onwards and the rapid reduction of coca plantations up to 2000, coca is still being cultivated in the tropical region of  Cochabamba. Technical and economic aspects are responsible for many farmers deciding to continue to cultivate coca and not to cultivate alternative crops. Coca cultivation

  9. Consecuencias del uso de cocaína en las personas que ejercen la prostitución Consequences of cocaine use among prostitutes

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    Carmen Meneses Falcón

    2007-06-01

    Full Text Available Objetivo: Describir las circunstancias y las consecuencias del consumo de cocaína en el entorno del ejercicio de la prostitución. Material y métodos: Estudio cualitativo sobre una muestra de 60 personas, de 18-50 años de edad, que ejercen la prostitución en la calle, apartamentos y clubs de 6 ciudades españolas, mediante entrevista semiestructurada. Resultados: El alcohol y la cocaína son las principales sustancias de consumo en este contexto. Se trata de consumos ocasionales e instrumentales que permiten a las personas que ejercen la prostitución sobrellevar la actividad que realizan, resistir muchas horas la prestación de prácticas sexuales con diferentes clientes, obtener mayores beneficios económicos y eludir los servicios sexuales. Las consecuencias del consumo por parte de estas personas pueden llevar a la desprotección en las prácticas sexuales y a ser víctimas de agresión o violencia por parte del cliente. Las personas prostituidas desarrollan estrategias de disminución del consumo: reducción de las dosis de consumo, simulación del uso de drogas o selección de los clientes consumidores. Conclusiones: El estudio destaca que los consumos de drogas se encuentran asociados al contexto de realización de los servicios sexuales. Sin embargo, las consecuencias de éstos pueden implicar riesgos para la salud por la desprotección de las prácticas sexuales que demanda el cliente.Objective: To describe the circumstances and consequences of cocaine use in the setting of prostitution. Material and method: We performed a qualitative study with fieldwork in 6 Spanish cities. Semi-structured interviews were carried out to 60 persons aged between 18 and 50 years old involved in prostitution in different settings: street, flat and brothel. Results: The main substances used in prostitution were alcohol and cocaine. Consumption was occasional and instrumental and helped to reduce psychological barriers or inhibition and increase

  10. Estudo in situ do efeito da freqüência de ingestão de Coca-Cola na erosão do esmalte-dentina e reversão pela saliva

    Directory of Open Access Journals (Sweden)

    FUSHIDA Claudia Emy

    1999-01-01

    Full Text Available O objetivo do presente trabalho foi uma avaliação intra-oral do efeito erosivo de refrigerante no esmalte-dentina e a capacidade da saliva em reverter as alterações, considerando a adequação do modelo e a inexistência de pesquisas em relação à dentina. Para tanto, foram utilizados dentes bovinos, a partir dos quais prepararam-se blocos de esmalte e dentina radicular adequados para determinação de microdureza superficial. Nove voluntários, utilizando dispositivos intra-orais palatinos contendo 4 blocos de esmalte e 4 de dentina, participaram deste estudo de 4 etapas, nas quais Coca-Cola foi ingerida de 1 a 8 vezes ao dia. Foram feitas determinações de microdureza superficial utilizando-se o aparelho SHIMADZU HMV 2000, e cargas de 50,0 e 15,0 g, respectivamente para esmalte e dentina, durante 5,0 segundos. Os resultados mostraram que, em função da freqüência de ingestão de Coca-Cola, a porcentagem de perda de dureza foi de 18,7 a 27,9 para o esmalte e de 24,6 a 32,6 para a dentina. Estas reduções foram estatisticamente significativas a 5% (teste "t" pareado. A porcentagem de recuperação de dureza pela ação da saliva foi parcial, porém significativa (p < 0,05, variando de 43,6 a 35,6 para o esmalte e de 40,5 a 34,6 para a dentina. Houve também uma correlação significativa entre freqüência de ingestão de Coca-Cola e % de perda de dureza, sendo de 0,97 para o esmalte e de 0,72 para a dentina. Por outro lado, em termos de recuperação de dureza, a correlação foi negativa, -0,70 para o esmalte e -0,74 para a dentina. Conclui-se que em função da freqüência de ingestão de Coca-Cola há perdas proporcionais e irreversíveis da estrutura superficial tanto do esmalte como da dentina.

  11. O papel das marcas nas dinâmicas sociais online: análise da presença das marcas concorrentes Pepsi e Coca-Cola, no facebook em Portugal

    OpenAIRE

    Mariano, Ana Filipa Costa

    2016-01-01

    presente dissertação pretende analisar a presença das marcas de grande consumo na rede social Facebook em Portugal, tendo por base o case study das marcas concorrentes Pepsi e Coca-Cola enquanto representantes do setor. A presença de marcas nas redes sociais é um tema atual, que levanta questões quanto à sua relevância e aceitação pelos utilizadores. Esta investigação permite-nos perceber a forma como os consumidores vêm esta situação, assim como, compreender quais as motivações que os lev...

  12. Evaluación de pasivos ambientales en el área de influencia del proyecto hidroeléctrico Coca Codo Sinclair (El Salado - Lumbaquí) y alternativas de remediación

    OpenAIRE

    Cuesta Soto, Irina Esthela

    2013-01-01

    Al iniciar los trabajos de construcción del Proyecto Hidroeléctrico Coca Codo Sinclair, se identifican varios puntos de contaminación por presencia de hidrocarburos, por lo que se reporta al Ministerio del Ambiente (MAE) el cual entabla reuniones con el Programa de Reparación Ambiental y Social (PRAS) y miembros de la Gerencia de Seguridad, Salud y Ambiente de la EP PETROECUADOR (SGER). Como resultado de las reuniones, se ve la necesidad de determinar los impactos negativos asociados a los pa...

  13. Estudio de los mecanismos subyacentes a las alteraciones mediadas por cocaína y metilfenidato en el sistema tálamo-cortical de ratón. Rol de la serotonina en la modulación de la transmisión GABAérgica talámica

    OpenAIRE

    Goitia, Belén

    2015-01-01

    Los efectos de la cocaína sobre la transmisión GABAérgica del sistema tálamocortical son similares a los previamente descritos para un conjunto de patologías psiquiátricas y neurológicas englobadas bajo el nombre de síndrome de disritmia tálamocortical, que presenta coherencia anormal entre bajas y altas frecuencias a nivel tálamocortical. Se cree que la presencia de bajas frecuencias en individuos despiertos puede subyacer un procesamiento sensorial anormal. La cocaína ejerce sus propiedades...

  14. A elaboração da face em comunidades virtuais de marca: um estudo de caso sobre uma comunidade virtual de consumidores da Coca-Cola

    Directory of Open Access Journals (Sweden)

    Grayci Kelli Alexandre de Freitas

    Full Text Available As mudanças por que passam a sociedade e as pessoas, em campos como comunicação, consumo e organização social, desde a concepção da modernidade, colocaram em xeque muitos conceitos que embasavam a compreensão a respeito das pessoas e das suas relações sociais, incluídas as de consumo. Destacamos, neste quadro, as interações sociais encenadas pelas pessoas e os caminhos que percorrem para a elaboração dos seus "eus". Partindo de uma realidade cujo uso massivo da Internet e o surgimento das comunidades virtuais são enfatizados, recortamos uma comunidade virtual da marca Coca-Cola como terreno para compreendermos que faces são elaboradas pelas pessoas quando se utilizam de signos marcários como mediadores em interações virtuais. Para tanto, adotamos as noções de "eu" e elaboração da face conforme concebidas por Goffman (2006, juntamente com a concepção de marca numa dimensão simbólica, enquanto recurso de representação social. Sob este arcabouço teórico, seguimos a perspectiva interpretativista para realizar este estudo de caso netnográfico por meio da análise de discurso funcional. Juntamente com estas orientações ontoepistemológicas e metodológicas, adotamos o método elaborado por Leão (2007 para acessarmos as interações virtuais concebidas como face a face. Catorze faces foram identificadas. Estas são descritas por meio de exemplos extraídos das observações, os quais são elucidativos do papel da marca estudada na dinâmica de negociação interacional entre os participantes, que caracteriza o processo de elaboração de faces. Contribuições para o conhecimento, bem como implicações gerenciais são consideradas.

  15. Drug Control: International Policy and Approaches

    National Research Council Canada - National Science Library

    Perl, Raphael

    2005-01-01

    ...: opium and marijuana production has roughly doubled and coca production tripled. Street prices of cocaine and heroin have fallen significantly in the past 20 years, reflecting increased availability...

  16. Srovnávací analýza organizační architekrury zahraničních a českých nadnárodních organizací (na příkladu společností Coca Cola, Pepsi Cola a Kofola)

    OpenAIRE

    Jurka, Petr

    2011-01-01

    The thesis explains the theoretical concepts of multinational corporation, organization, different types of organizational structures and indicators used for the analysis of organizational structures. In the practical part, the author describes the structure of Coca Cola, PepsiCo and Kofola, analyzes the selected indicators for individual companies and also focuses on similar and different features of the organizational structures of these companies. In conclusion, the author establishes the ...

  17. Simultaneous analysis of aspartame and its hydrolysis products of Coca-Cola Zero by on-line postcolumn derivation fluorescence detection and ultraviolet detection coupled two-dimensional high-performance liquid chromatography.

    Science.gov (United States)

    Cheng, Cheanyeh; Wu, Shing-Chen

    2011-05-20

    An innovative two-dimensional high-performance liquid chromatography system was developed for the simultaneous analysis of aspartame and its hydrolysis products of Coca-Cola Zero. A C8 reversed-phase chromatographic column with ultraviolet detection was used as the first dimension for the determination of aspartame, and a ligand-exchange chromatographic column with on-line postcolumn derivation fluorescence detection was employed as the second dimension for the analysis of amino acid enantiomers. The fluorimetric derivative reagent of amino acid enantiomers was o-phthaldialdehyde. The hydrolysis of aspartame in Coca-Cola Zero was induced by electric-heating or microwave heating. Aspartame was quantified by the matrix matched external standard calibration curve with a linear concentration range of 0-50 μg mL(-1) (r(2)=0.9984). The limit of detection (LOD) and the limit of quantification (LOQ) were 1.3 μg mL(-1) and 4.3 μg mL(-1), respectively. The amino acid enantiomers was analyzed by the matrix matched internal standard calibration method (D-leucine as the internal standard) with a linear concentration range of 0-10 μg mL(-1) (r(2)=0.9988-0.9997). The LODs and LOQs for L- and D-aspartic acid and L- and D-phenylalanine were 0.16-0.17 μg mL(-1) and 0.52-0.55 μg mL(-1), respectively, that was 12-13 times more sensitive than ultraviolet detection. The overall analysis accuracy for aspartame and amino acid enantiomers was 90.2-99.2% and 90.4-96.2%, respectively. The overall analysis precision for aspartame and amino acid enantiomers was 0.1-1.7% and 0.5-6.7%, respectively. Generally, the extent of aspartame hydrolysis increases with the increase of electro-thermal temperature, microwave power, and the duration of hydrolysis time. D-aspartic acid and D-phenylalanine can be observed with the electro-thermal racemization at the hydrolysis temperature 120°C for 1 day and only D-aspartic acid can be observed at the hydrolysis temperature 90°C for 2 and 3 days. For

  18. Pieprasījuma veicināšanas iespējas „Coca – Cola HBC Latvia” uzņēmumā krīzes apstākļos

    OpenAIRE

    Petjukeviča, Tatjana

    2010-01-01

    Bakalaura darba mērķis ir izpētot Latvijas bezalkoholisku dzērienu nozares attīstības tendences un vadošo uzņēmuma menedžmentu, atrast pieprasījuma veicināšanas iespējas „Coca-Cola HBC Latvia” uzņēmuma produkcijai krīzes apstākļos. Šis uzņēmums ir viens no Latvijas vadošajiem uzņēmumiem bezalkoholisko dzērienu tirdzniecībā, tomēr krīze negatīvi ietekmēja uz tā neto apgrozījuma izmaiņām, tāpēc ir nepieciešams izstrādāt vairākus pasākumus pieprasījuma veicināšanai šā uzņēmuma produkcijai. Darba...

  19. Atividades Marcárias como Recursos de Elaboração da Face em Comunidades Virtuais de Marca: Análise de uma Comunidade Virtual de Consumidores Da Coca-Cola

    Directory of Open Access Journals (Sweden)

    André Luiz Maranhão de Souza Leão

    2010-10-01

    Full Text Available As relações interpessoais sofreram mudanças expressivas após a inserção da internet na vida social. Deste contexto, podemos destacar as comunidades virtuais e, mais especificamente, comunidades virtuais de marcas. Assumindo que o “eu” seja uma construção social promovida nas interações sociais, este estudo objetiva analisar o comportamento verbal de participantes de comunidades virtuais de marcas em relação a estas como meio de elaboração de suas faces (Goffman, 2006. Neste sentido, assumimos a noção de o que e como dizemos as coisas são comportamentos sociais (Austin, 1990 e utilizamos o conceito de “atividades marcárias”, desenvolvido por Leão e Mello (2009. Para tal, selecionamos uma comunidade de consumidores da Coca-Cola como terreno investigativo, onde realizamos uma “netnografia da comunicação”, suportada por uma análise de discurso funcional. Por fim, aspectos teóricos e práticos são considerados. DOI: 10.5585/remark.v9i2.2168

  20. POSTKAPİTALİST DÖNEMDE KÜRESEL MARKALARIN YENİ PAZARLAMA STRATEJİSİ: KİTLELERİN YENİ YAŞAM KOÇU OLARAK COCA COLA

    OpenAIRE

    SEVİM, Bilgen

    2018-01-01

    2000’li yıllarda küresel ölçekli markaların reklam söyleminde büyük bir dönüşüm yaşanmıştır. Bu markalar, “sevgi”, “umut”, “mutluluk”, “yardımseverlik”, “aşk” ve “barış” gibi kavramları kullanarak yaşamın anlamına dair mesajlar vermeye başlamışlardır. Interbrand’ın raporuna göre, 2012 yılında dünyanın en değerli markası seçilen Coca Cola’nın Türkiye için hazırladığı Yeni yıl, Yeni Umutlar (2012), Bimilyonneden Yeni Yıl (2012), Güvenlik Kameraları (2012), Daha İyi Bir Yıl (2013) Yeni Yıla Yaln...

  1. Estudio de parámetros metabólicos en sujetos jóvenes sometidos a ejercicio sub-máximo después de la administración de mate de coca, en la exposición aguda de altura

    OpenAIRE

    Mujica, Elydia; Ronceros, Gerardo; Torres, Javier; Pinto, Rogelio; Ponciano, Walter; Bravo, Yelitz; López, Milena; Gallardo, Duber; Salinas, César; Calderón, Segundo; Villareal, Carmen; Yampufé, Manuel

    2013-01-01

    Objetivos: Determinar los parámetros metabólicos glucosa, colesterol, triglicéridos, HDL, en sujetos jóvenes sometidos a ejercicio sub-máximo después de la administración de mate de coca, en exposición aguda de altura. Diseño: Estudio experimental. Institución: Instituto Nacional de Biología Andina. Instituto de Investigaciones Clínicas y Sección Fisiología de la Facultad de Medicina, UNMSM. Participantes: Estudiantes universitarios varones nativos del nivel del mar. Intervenciones: Se estudi...

  2. Normas percibidas por los estudiantes universitarios hondureños acerca de sus pares y el uso de tabaco, alcohol, marihuana y cocaína Normas percebidas pelos estudantes universitários hondurenhos sobre os pares e o uso de tabaco, álcool, maconha e cocaína Perceived norms among honduran university students about peers and tobacco, alcohol, marijuana and cocaine use

    Directory of Open Access Journals (Sweden)

    Syntia Dinora Santos Figueroa

    2009-01-01

    Full Text Available El propósito del presente estudio fue estimar la diferencia entre las normas percibidas sobre el uso de drogas por los pares y el uso real informado por estudiantes universitarios, entre 18 a 24 años, del segundo y tercer año en el área de Educación. La teoría de las Normas Sociales fue usada como marco referencial. 286 estudiantes participaron en el estudio, el 67% expresó haber consumido alcohol al menos una vez en la vida y el 28% declaró consumirlo diariamente. Los estudiantes percibieron que 62% de sus compañeros consumen tabaco y el 63% alcohol. El estándar percibido de consumo de drogas fue ligeramente más alto entre las mujeres que en los hombres. Se concluye que los resultados indican una sobreestimación al compararse el estándar percibido con el consumo informado de tabaco y alcohol así como de marihuana y cocaína.O objetivo do presente estudo foi estimar a diferença entre as normas percebidas sobre o uso de drogas pelos pares e o próprio uso em estudantes universitários, entre 18 e 24 anos, do segundo e terceiro ano da área de educação. A teoria das Normas Sociais foi usada como marco referencial. Participaram do estudo 286 estudantes, sendo que 67% declararam ter consumido álcool ao menos uma vez na vida e 28%, diariamente. Os estudantes estimaram que 62% dos pares consomem tabaco e 63%, álcool. A norma percebida para o consumo de drogas foi ligeiramente mais alta em mulheres do que em homens. Como conclusão os resultados indicaram hiperestimativa ao se comparar a norma percebida com o próprio consumo, em relação ao tabaco, ao álcool, à maconha e à cocaína.The purpose of this study was to assess the difference between perceived norms and peers' drug use among sophomore and junior university students (from the field of education aged 18 to 24 years. The Social Norms Theory was used as the theoretical framework. In total, 286 students participated in the study, 67% of which reported having consumed

  3. 75 FR 36681 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-06-28

    ... Anileridine (9020) II Bezitramide (9800) II Carfentanil (9743) II Coca Leaves (9040) II Cocaine (9041) II..., concentrate of poppy straw, and coca leaves. As explained in the Correction to Notice of Application... schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act (21 U.S.C. 952 (a)(2...

  4. 77 FR 4831 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2012-01-31

    ... (8501) II Coca Leaves (9040) II Oxycodone (9143) II Hydromorphone (9150) II Hydrocodone (9193) II... crude opium, poppy straw, poppy straw concentrate, and coca leaves. As explained in the Correction to... schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act 21 U.S.C. 952 (a)(2)(B...

  5. 76 FR 77253 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-12-12

    ... Schedule Coca Leaves (9040) II Thebaine (9333) II Opium, raw (9600) II Noroxymorphone (9668) II Poppy Straw...-registration to import crude opium, poppy straw, concentrate of poppy straw, and coca leaves. Comments and... substances listed in schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act (21...

  6. Geometrid larvae (Lepidoptera) and their parasitoids, associated to Erythroxylum microphyllum St.-Hilaire (Erythroxylaceae)

    OpenAIRE

    Marconato, Gláucia; Dias, Manoel Martins; Penteado-Dias, Angélica Maria

    2008-01-01

    O trabalho foi realizado em área de cerrado, em São Carlos, São Paulo, Brasil. Foram realizadas amostragens quinzenais de junho/1999 a junho/2000, por meio de guarda-chuva-entomológico. Foram registradas 22 espécies de Geometridae pertencentes a 14 gêneros; quanto aos parasitóides, 11 gêneros de Hymenoptera e dois de Diptera, Tachinidae. A ocorrência de Cyclomia mopsaria (Geometridae) foi de 83%. Outros Geometridae registrados foram: Glena unipennaria, G. bipennaria, G. demissaria, G. brachia...

  7. Prevalência da exposição pré-natal à cocaína em uma amostra de recém-nascidos de um hospital geral universitário Prevalence of prenatal exposure to cocaine in a sample of newborns from a university teaching hospital

    Directory of Open Access Journals (Sweden)

    Gabrielle B. da Cunha

    2001-10-01

    Full Text Available OBJETIVO: verificar a prevalência da exposição pré-natal à cocaína em uma amostra de recém-nascidos utilizando dois métodos: a fluorescência polarizada por imunoensaio no mecônio e a entrevista materna. MÉTODO: estudo transversal realizado num hospital geral universitário, abrangendo todos os recém-nascidos nascidos vivos no centro obstétrico do hospital durante o período de 23 de março de 1999 a 1 de junho de 1999 (847 recém-nascidos. A presença de exposição pré-natal à cocaína foi definida por um teste de fluorescência polarizada por imunoensaio positivo para benzoilecgonina no mecônio do RN e/ou por uma entrevista materna positiva. RESULTADOS: a taxa da exposição pré-natal à cocaína foi de 16 casos (2,4%, através da entrevista, e de 25 casos (3,4% através da testagem do mecônio. Foram encontrados 34 casos, com uma prevalência de 4,6%, quando os métodos para a detecção foram considerados de forma complementar. CONCLUSÕES: através deste estudo, foi observado que a testagem meconial é mais eficaz que a entrevista materna no diagnóstico da exposição pré-natal à cocaína. A entrevista aumentou, em relação à testagem do mecônio, em 26% a possibilidade do diagnóstico da exposição; e a testagem do mecônio, em relação à entrevista, aumentou em 53,4% o diagnóstico da exposição.OBJECTIVE: to assess the prevalence of prenatal exposure to cocaine in a sample of newborns using two methods: fluorescence polarization immunoassay and interview with the mother. METHODS: this cross-sectional study was carried out in a university teaching hospital. The population included all live births between March 23, 1999 and June 01, 1999 (n=847. Exposure was determined by a benzoylecgonine-positive meconium specimen and/or by a positive interview with the mother. RESULTS: the prevalence of prenatal exposure to cocaine in this sample was 2.4% (16 cases according to the interviews, and 3.4% (25 cases according to

  8. 77 FR 70824 - Importer of Controlled Substances; Notice of Application; Johnson Matthey, Inc.

    Science.gov (United States)

    2012-11-27

    ... Coca Leaves (9040) II Thebaine (9333) II Opium, raw (9600) II Noroxymorphone (9668) II Poppy Straw...-registration to import crude opium, poppy straw, concentrate of poppy straw, and coca leaves. Comments and... substances listed in schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act (21...

  9. Acute toxicity and sublethal effects of the mixture glyphosate (Roundup® Active and Cosmo-Flux®411F to anuran embryos and tadpoles of four Colombian species

    Directory of Open Access Journals (Sweden)

    Liliana Marcela Henao Muñoz

    2015-03-01

    Full Text Available Glyphosate is the most widely used herbicide in the world with application in agriculture, forestry, industrial weed control, garden and aquatic environments. However, its use is highly controversial for the possible impact on not-target organisms, such as amphibians, which are vanishing at an alarming and rapid rate. Due to the high solubility in water and ionic nature, the glyphosate requires of surfactants to increase activity. In addition, for the control of coca (Erythroxylum coca and agricultural weeds in Colombia, formulated glyphosate is mixed and sprayed with the adjuvant Cosmo-Flux®411F to increase the penetration and activity of the herbicide. This study evaluates the acute toxic and sublethal effects (embryonic development, tadpole body size, tadpole swimming performance of the mixture of the formulated glyphosate Roundup® Active and Cosmo-Flux®411F to anuran embryos and tadpoles of four Colombian species under 96h laboratory standard tests and microcosms, which are more similar to field conditions as they include soil, sand and macrophytes. In the laboratory, embryos and tadpoles of Engystomops pustulosus were the most tolerant (LC50=3 904µg a.e./L; LC50=2 799µg a.e./L, respectively, while embryos and tadpoles of Hypsiboas crepitans (LC50=2 203µg a.e./L; LC50=1 424µg a.e./L, respectively were the most sensitive. R. humboldti and R. marina presented an intermediate toxicity. Embryos were significantly more tolerant to the mixture than tadpoles, which could be likely attributed to the exclusion of chemicals by the embryonic membranes and the lack of organs, such as gills, which are sensitive to surfactants. Sublethal effects were observed for the tadpole body size, but not for the embryonic development and tadpole swimming performance. In microcosms, no toxicity (LC50 could not be estimated, or sublethal responses were observed at concentrations up to fourfold (14.76kg glyphosate a.e./ha the highest field application rate of 3

  10. Hamburger, lit and coca-cola Hamburger, lit and coca-cola

    Directory of Open Access Journals (Sweden)

    Leslie Fiedler

    2008-04-01

    Full Text Available What I would like to do today is begin by talking a little while about something I had on my mind, but still remains unspoken, including a few words about my next to the last book Freaks and the book that will probably be called "What Was Literature". After I finish talking about those things for a short time I'd like to open the floor up for questions because I know, two or three people have told me already they have questions which they'd want to ask, and I'm sure some of the rest of you have questions you have asked before and have thought I have not adequately answered. What I would like to do today is begin by talking a little while about something I had on my mind, but still remains unspoken, including a few words about my next to the last book Freaks and the book that will probably be called "What Was Literature". After I finish talking about those things for a short time I'd like to open the floor up for questions because I know, two or three people have told me already they have questions which they'd want to ask, and I'm sure some of the rest of you have questions you have asked before and have thought I have not adequately answered.

  11. Hamburger, lit and coca-cola Hamburger, lit and coca-cola

    OpenAIRE

    Leslie Fiedler

    2008-01-01

    What I would like to do today is begin by talking a little while about something I had on my mind, but still remains unspoken, including a few words about my next to the last book Freaks and the book that will probably be called "What Was Literature". After I finish talking about those things for a short time I'd like to open the floor up for questions because I know, two or three people have told me already they have questions which they'd want to ask, and I'm sure some of the rest of y...

  12. Cocaína: complicaciones obstétricas, médicas y perinatales. Características clínicas y tratamiento a estas pacientes Cocaine: obstetric, medical and perinatal complications. Clinical characteristics and treatment of these patients

    Directory of Open Access Journals (Sweden)

    Miguel Lugones Botell

    2005-08-01

    Full Text Available Se realizó una revisión sobre los efectos generales de la cocaína, y en particular, sobre el embarazo y el recién nacido, en la que se enfatiza en los efectos deletéreos que tiene esta droga sobre la gestación, entre los que se destacan el bajo peso al nacer, el hematoma retroplacentario, la hipertensión arterial y la muerte fetal, entre otras complicaciones, así como también las consecuencias negativas que provoca sobre el producto de la concepción. Se hacen consideraciones acerca del manejo integral que hay que tener sobre estas pacientes.A review on the general effects of cocaine and, in particular, on its effects on pregnancy and the newborn infant, was made. Low birth weight, retroplacental hematoma, arterial hypertension and fetal death, are some of the deleterious effects of this drug on gestation that were emphazised, among other complications, as well as its negative consequences for the product of conception. Considerations are made on the comprehensive management of these patients.

  13. Korporatīvā sociālā atbildība: patērētāju uztveres un korporāciju komunikācijas analīze starptautiskajos tirgos uz McDonald's un Coca-Cola piemēra.

    OpenAIRE

    Teterins, Pāvels

    2016-01-01

    Korporatīvās sociālās atbildības (KSA) komunikācijas efektivitātes pamats ir pielāgošanās patērētāju prasībām. Pētījuma mērķis bija uz McDonald’s un Coca-Cola sociālo tīklu KSA komunikācijas piemēra, izvērtēt to, vai kompānijas pielāgo KSA komunikāciju patērētāju vērtējumam par atbildīgu uzņēmējdarbību, un piedāvāt optimālu KSA komunikācijas struktūru. Demogrāfisko faktoru ietekme uz Latvijas, Vācijas un Austrālijas KSA vērtējumu praktiski netika novērota. Savukārt, salīdzinot valstis savā st...

  14. Comportamento motor oral e global de recém-nascidos de mães usuárias de crack e/ou cocaína Oral and general motor behavior of newborns from crack and/or cocaine using mothers

    Directory of Open Access Journals (Sweden)

    Marisa Gasparin

    2012-12-01

    Full Text Available OBJETIVO: Analisar o comportamento motor oral e global de recém-nascidos de mães que fizeram uso de crack e/ou cocaína durante a gestação e verificar se há relação entre o desenvolvimento dos sistemas sensório motor oral (SSMO e motor global. MÉTODOS: Estudo transversal, em que foram avaliados 25 recém-nascidos prematuros e a termo de mães usuárias de crack e/ou cocaína, pareados com outro grupo de 25 recém-nascidos sem o fator em estudo. As avaliações do SSMO e motor global foram realizadas por meio do Instrumento de Avaliação da Prontidão do Prematuro para Início da Alimentação Oral e do Test of Infant Motor Performance (TIMP, respectivamente. Os resultados compararam os escores encontrados nas duas escalas e a relação destes com o uso materno do crack e/ou cocaína durante a gestação. RESULTADOS: No TIMP não foi constatada diferença na comparação entre os escores de recém-nascidos de mães usuárias de crack e/ou cocaína e os de mães não usuárias. No Instrumento de Avaliação da Prontidão do Prematuro para Início da Alimentação Oral, os resultados apresentaram diferença. Foi observada associação entre os resultados de bebês que apresentaram atraso no TIMP com menor escore no Instrumento de Avaliação da Prontidão do Prematuro para Início da Alimentação Oral. CONCLUSÃO: O baixo desempenho observado no Instrumento de Avaliação da Prontidão do Prematuro para Início da Alimentação Oral sugere que as respostas motoras orais estão alteradas pelo uso materno das drogas. A correlação entre os dois instrumentos mostra que o desenvolvimento do SSMO pode estar relacionado ao desenvolvimento motor global.PURPOSE: analyzing the oral and general motor behavior of newborns from women who used crack and/or cocaine during pregnancy, and verifying if there is a relation between the development of the oral and general sensory motor system. METHODS: Cross-sectional study with 25 premature and full

  15. Larvas de Geometridae (Lepidoptera e seus parasitóides, associadas a Erythroxylum microphyllum St.- Hilaire (Erythroxylaceae Geometrid larvae (Lepidoptera and their parasitoids, associated to Erythroxylum microphyllum St.-Hilaire (Erythroxylaceae

    Directory of Open Access Journals (Sweden)

    Gláucia Marconato

    2008-01-01

    Full Text Available O trabalho foi realizado em área de cerrado, em São Carlos, São Paulo, Brasil. Foram realizadas amostragens quinzenais de junho/1999 a junho/2000, por meio de guarda-chuva-entomológico. Foram registradas 22 espécies de Geometridae pertencentes a 14 gêneros; quanto aos parasitóides, 11 gêneros de Hymenoptera e dois de Diptera, Tachinidae. A ocorrência de Cyclomia mopsaria (Geometridae foi de 83%. Outros Geometridae registrados foram: Glena unipennaria, G. bipennaria, G. demissaria, G. brachia, Physocleora junctilinea, P. cariaria, Physocleora sp., Iridopsis fulvitincta, I. nigraria, Hymenomima amberia, Macaria regulata, Ischnopteris inornata., Prochoerodes onustaria, Prochoerodes sp., Thyrinteina arnobia, Nematocampa sp., Melanolophia sp., Isochromodes sp., Semaeopus lunifera, S. vizaria. Os Hymenoptera foram: Microcharops peronata, Charops sp., Metopius sp., Hyposoter sp., Mesochorus sp.(Ichneumonidae; Aleiodes sp., Meteorus sp., Glyptapanteles sp., Protapanteles sp. (Braconidae; Euplectrus sp. (Eulophidae. Os Diptera, Tachinidae foram: Winthemia sp.(Winthemiini e uma espécie de Blondeliini. O período de maior ocorrência de larvas de Geometridae e baixa taxa de parasitismo foi ao final da estação chuvosa e início da estação seca.This work was carried out in a cerrado area, in São Carlos, São Paulo, Brazil. The samples were collected at each two weeks, from June/1999 to June/2000, with entomological umbrella. 22 species of Geometridae arranged in 14 genera were found; concerning parasitoids, 11 genera of Hymenoptera and two genera of Diptera, Tachinidae. The occurrence of Cyclomia mopsaria (Geometridae was 83%. Other Geometridae recorded were: Glena unipennaria, G. bipennaria, G. demissaria, G. brachia, Physocleora junctilinea, P. cariaria, Physocleora sp., Iridopsis fulvitincta, I. nigraria, Hymenomima amberia, Macaria regulata, Ischnopteris inornata, Prochoerodes onustaria, Prochoerodes sp., Thyrinteina arnobia, Nematocampa sp., Melanolophia sp., Isochromodes sp., Semaeopus lunifera, S. vizaria. The Hymenoptera were: Microcharops peronata, Charops sp., Metopius sp., Hyposoter sp., Mesochorus sp. (Ichneumonidae; Aleiodes sp., Meteorus sp., Glyptapanteles sp., Protapanteles sp. (Braconidae; Euplectrus sp. (Eulophidae. The Diptera, Tachinidae were: Winthemia sp. (Winthemiini and a Blondeliini species. The period of higher occurrence of Geometridae larvae and lowest rate of parasitism was during the end of rainy season and the beginning of the dry season.

  16. 77 FR 34069 - Importer of Controlled Substances; Notice of Application; Research Triangle Institute

    Science.gov (United States)

    2012-06-08

    ... Carfentanil (9743) II Coca Leaves (9040) II Cocaine (9041) II Codeine (9050) II Dextropropoxyphene, bulk (non... substances listed in schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act (21...

  17. 78 FR 39337 - Importer of Controlled Substances; Notice Of Registration; Mallinckrodt, LLC.

    Science.gov (United States)

    2013-07-01

    ... Phenylacetone (8501) II Coca Leaves (9040) II Opium, raw (9600) II Poppy Straw Concentrate (9670) II The company... States obligations under international treaties, conventions, or protocols in effect on May 1, 1971. DEA...

  18. Controlling Cocaine: Supplying Versus Demand Programs

    Science.gov (United States)

    1994-01-01

    treatment dura - tions are less than a year, which means that each treatment space can serve more than one person during a year and the cost per admission...May-June, pp. 355-365. Holloway, Marguerite (1991), "Rx for Addiction," Scientific American, March, pp. 93- 103. Holmes, Steven A. (1993), "Coca

  19. Larvas de Geometridae (Lepidoptera) e seus parasitóides, associadas a Erythroxylum microphyllum St.- Hilaire (Erythroxylaceae)

    OpenAIRE

    Marconato,Gláucia; Dias,Manoel Martins; Penteado-Dias,Angélica Maria

    2008-01-01

    O trabalho foi realizado em área de cerrado, em São Carlos, São Paulo, Brasil. Foram realizadas amostragens quinzenais de junho/1999 a junho/2000, por meio de guarda-chuva-entomológico. Foram registradas 22 espécies de Geometridae pertencentes a 14 gêneros; quanto aos parasitóides, 11 gêneros de Hymenoptera e dois de Diptera, Tachinidae. A ocorrência de Cyclomia mopsaria (Geometridae) foi de 83%. Outros Geometridae registrados foram: Glena unipennaria, G. bipennaria, G. demissaria, G. brachia...

  20. Estratégias mercadológicas de empresas transnacionais em um mercado global marcado por diferentes níveis de desenvolvimento das nações: um estudo de caso da the coca-cola company 10.5102/uri.v9i1.1339

    Directory of Open Access Journals (Sweden)

    Luciana Cantuária Lôbo

    2011-06-01

    Full Text Available Este trabalho buscou verificar o grau de alinhamento da estratégia de composição do mix de produtos das empresas transnacionais aos diferentes níveis de desenvolvimento dos mercados consumidores dos países onde atuam. Para atender a esse objetivo, a pesquisa seguiu uma concepção descritiva-quantitativa, e se baseou no método de estudo de caso único da empresa The Coca-Cola Company. A metodologia adotada se baseou no cálculo do índice de correlação de Pearson entre duas variáveis: o Índice de Desenvolvimento Humano e o número de categorias de produtos comercializados em cada país onde a empresa estudada opera. Os resultados mostram uma alta correlação positiva entre as duas variáveis consideradas. Assim, acredita-se que a principal contribuição deste trabalho é apontar para a estratégia de adequação local da organização estudada para atender as necessidades específicas da população de forma rentável em cada país, na medida em que se percebe que as novas tendências de consumo não necessariamente estão ocorrendo de forma homogênea entre as nações, notadamente entre as de alto e baixo IDH.

  1. Brain injury markers (S100B and NSE) in chronic cocaine dependents Marcadores de lesão cerebral (S100B e NSE) em dependentes crônicos de cocaína

    OpenAIRE

    Felix Henrique Paim Kessler; George Woody; Luís Valmor Cruz Portela; Adriano Bretanha Lopes Tort; Raquel De Boni; Ana Carolina Wolf Baldino Peuker; Vanessa Genro; Lísia von Diemen; Diogo Onofre Gomes de Souza; Flavio Pechansky

    2007-01-01

    OBJECTIVE: Studies have shown signs of brain damage caused by different mechanisms in cocaine users. The serum neuron specific enolase and S100B protein are considered specific biochemical markers of neuronal and glial cell injury. This study aimed at comparing blood levels of S100B and NSE in chronic cocaine users and in volunteers who did not use cocaine or other illicit drugs. METHOD: Twenty subjects dependent on cocaine but not on alcohol or marijuana, and 20 non-substance using controls ...

  2. Using thought mapping and structured stories to decrease HIV risk behaviors among cocaine injectors and crack smokers in the South of Brazil A utilização do mapeamento cognitivo e de histórias estruturadas para diminuir comportamentos de risco para a contaminação pelo HIV entre consumidores de cocaína injetável e de crack no Sul do Brasil

    Directory of Open Access Journals (Sweden)

    Flavio Pechansky

    2007-09-01

    Full Text Available OBJECTIVES: To compare changes in AIDS knowledge and risk behaviors among Brazilian cocaine users in an intervention trial. METHOD: 119 participants were randomly assigned to either a standard or a standard plus "thought mapping" intervention, and re-interviewed 2 and 8 weeks after intake using standardized data collection instruments. Intervention effects were examined using generalized estimated equation model. RESULTS: Significant increases in AIDS knowledge and condom use were observed in the experimental group, as well as significant changes in the subscores for sexual and drug risks. The experimental intervention was less successful in decreasing mean days of cocaine use when compared to the standard. CONCLUSION: Although not robust, the findings nevertheless suggest that components of the experimental thought-mapping model might be useful in combination with other approaches.OBJETIVOS: Comparar as mudanças em conhecimento sobre AIDS e comportamentos de risco em usuários de cocaína brasileiros submetidos a uma intervenção experimental. MÉTODO: 119 sujeitos foram aleatoriamente designados para uma intervenção padrão ou uma intervenção padrão adicionada a um "mapa cognitivo", e re-entrevistados duas e oito semanas após admissão no estudo, utilizando-se instrumentos de coleta padronizados. Os efeitos da intervenção foram examinados utilizando modelo de equações de estimação generalizadas. RESULTADOS: Foram observados aumentos significativos no conhecimento sobre AIDS e uso de preservativos no grupo experimental, bem como modificações significativas nos subescores para risco sexual e uso de drogas. A intervenção experimental teve menos sucesso em diminuir dias de uso de cocaína quando comparada com a intervenção padrão. CONCLUSÃO: Apesar de não serem robustos, os achados sugerem que os componentes do modelo de mapa cognitivo experimentados poderiam ser úteis em combinação com outras abordagens.

  3. “I hate coke”: an nethnographic analysis about speech anti-brand of the virtual community on orkut “Eu odeio Coca-Cola”: uma análise netnográfica sobre o discurso antimarca da comunidade virtual do orkut

    Directory of Open Access Journals (Sweden)

    Márcio Moutinho Abdalla

    2011-12-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabela normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} It is evident broad organizational concerns regarding the management and maintenance of their brands. Retaliatory and repudiation action against product and services brands are shown as imposing barriers to be implemented by organizations. Thus, this study aims to deepen understanding of the subject by analyzing the speech of members of the virtual community antibrand "eu odeio coca-cola (I hate Coke" in Orkut social network, besides seeking the motivations that led these members to express their opinions. As research procedures, drew on an exploratory analysis by conducting a search netnography, which led the researchers to immerse themselves in the community for a period of one year, featuring a longitudinal study. For the analysis of information, was employed discourse analysis, which enabled the categorization of the motivations for community members to express their opinions. As a result, we found six categories of behavior, which were (1 negative experience of consumption, (2 brand association with health/aesthetics problems, (3 presumed use of illicit material in the product, (4 concern with the effects of globalization, and

  4. The monitoring of trade in and control of psychotropic substances to guard against their diversion.

    Science.gov (United States)

    Bayer, I

    1983-01-01

    The establishment of international control of opiates has been an important achievement of the international community; this is substantiated by the fact that, at the beginning of this century, legally manufactured morphine and heroin were the principal sources of illicit supply, whereas at present the illicit traffic in these drugs is supplied from illicit sources. The poppy straw process has helped to promote measures to control opium poppy cultivation in a number of European countries; Turkey has been a successful example of such control. The present large-scale illicit traffic in cannabis resin and cocaine is the consequence of the lack of the implementation of provisions of the Single Convention on Narcotic Drugs, 1961, to control the cannabis plant and the coca bush at the national level. The provisions of the 1971 Convention on Psychotropic Substances, being largely a result of international compromise, are not designed in the best possible way to prevent the diversion of psychotropic substances from legal sources to illicit channels. There are no appropriate provisions for the control and monitoring of international transactions. There is a discrepancy between the rather limited scope of international control of substances listed in schedules III and IV of the 1971 Convention and the much larger scope of control of hypnotics, sedatives and tranquillizers at national levels. The provisions of the 1971 Convention, however, constitute a legal basis for bilateral and multilateral actions for the detection of suspected diversion cases, and offer possibilities of promoting the prevention of diversion of psychotropic substances. At present, the relationship between the control of psychotropic drugs, including the prevention of diversion and the organization of the national drug supply system, as well as the efficacy of national control over pharmaceutical products, has not been fully recognized by the international community.

  5. 75 FR 69459 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-11-12

    ..., poppy straw, concentrate of poppy straw, and coca leaves. As explained in the Correction to Notice of... schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act [(21 U.S.C. 952 (a)(2...

  6. 77 FR 2321 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2012-01-17

    ..., poppy straw, concentrate of poppy straw, and coca leaves. As explained in the Correction to Notice of... schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act 21 U.S.C. 952(a)(2)(B...

  7. 76 FR 51399 - Importer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-08-18

    ..., concentrate of poppy straw or coca leaves. As explained in the Correction to Notice of Application pertaining... schedule I or II, which fall under the authority of section 1002(a)(2)(B) of the Act (21 U.S.C. 952(a)(2)(B...

  8. Two boys and a can of coca-cola

    Science.gov (United States)

    Partensky, Michael B.

    2002-02-01

    A barometric analogy imposes a limit ˜10 meters for a height from which one can sip Coke through a straw from a can placed on the ground. How did Jeff manage to overcome this restriction without using anyone's help or tools? One possible solution is offered.

  9. Wine and Coca Cola: Serendipity and Entrepreneurial success

    Science.gov (United States)

    Wyatt, Philip

    2007-03-01

    Starting a new company from scratch depends critically on identifying a product for which there will be enough demand to generate a profit after a reasonable time period. Many start-ups nowadays obtain early Government grants or contracts (e. g. the so-called SBIR programs), but until such contracts begin (if ever!) to provide positive cash flow, a source of other funds become essential. Despite contracts, venture capital, and some friends willing to ``gamble,'' our first entrepreneurial venture ended not with a bang, but a whimper! We had chosen the wrong market. On the day before the company closed its doors, an unanticipated event occurred. We had opened a few bottles of wine for our final farewell but, as we began drinking, we decided to study their laser-scattering properties with our unappreciated and failed instrumentation. The resulting press coverage of a paper reporting that ``tasting'' was phenomenal, though it was published too late to save the company. Starting a second entrepreneurial venture was far more difficult as the first ``angels'' were nowhere to be found. A forgotten proposal by that failed first venture was suddenly funded providing, thereby, the means to start the second. As the second venture began, the success of the wine paper suggested that trying the same method with cola drinks might prove interesting. A new paper reporting on those results was immediately picked up by Applied Optics for an issue cover. At first, a particular cola manufacturer was not amused. However, it soon recognized the significance of laser scattering and began to contribute to the Company's support. Complemented by their largesse and the newly funded contract, the Company's instrumentation commercialization programs became sharply focused: refine the development and sale of a new type of absolute light scattering photometer incorporating a laser. We never looked back.

  10. Coca-Cola otdõhhajet / Viktoria Panova

    Index Scriptorium Estoniae

    Panova, Viktoria

    2006-01-01

    10. Pimedate Ööde Filmifestival algab. Festivali toimumispaikadest, filmiprogrammidest, alafestivalidest : animafestival Animated Dreams, tudengifilmifestival Sleepwalkers, laste- ja noortefilmi festival Just

  11. History and efficacy of emergency contraception: beyond Coca-Cola.

    Science.gov (United States)

    Ellertson, C

    1996-01-01

    Over 30 years of clinical use of emergency contraception has confirmed that such methods substantially reduce the chances of pregnancy, do not entail onerous service provision requirements, and are acceptable to women. The major obstacle to the more widespread use of postcoital methods is a lack of awareness on the part of both potential acceptors and service providers of this important option. Most extensively researched have been the Yuzpe method (200 mcg of ethinyl estradiol and 1.0 mg of levonorgestrel, taken within 72 hours of unprotected intercourse and then 12 hours later), levonorgestrel (two doses of 0.75 mg 12 hours apart starting within 48 hours of unprotected intercourse), and postcoital insertion of a copper IUD. Two new agents--RU-486 and the synthetic progestin and antigonadotropin danazol--offer promise, but require further evaluation. The Yuzpe method is estimated to reduce the likelihood of pregnancy by at least 75%. Lacking in the available literature are studies with rigorous research designs and methodologies capable of generating reliable data on efficacy and side effects, especially among women in developing countries. There is a need, for example, to limit samples to women who have had only one act of unprotected intercourse during a menstrual cycle and to those of proven fertility. Also important are studies that evaluate a range of distributional systems (e.g., vending machines) and user educational approaches. Finally, studies are needed to determine whether the Yuzpe method can be broadened to encompass all the progestins (e.g., desogestrel) used in combined oral contraceptives.

  12. ANALIZA LOJALNOSTI ODJEMALCEV DO IZDELKOV ZNAMKE COCA-COLA

    OpenAIRE

    Šauperl, Matej

    2012-01-01

    Zadovoljstvo odjemalcev predstavlja za podjetja pomembno vlogo pri zagotavljanju uspešnih poslovnih rezultatov in ohranjanju konkurenčnega tržnega deleža. Z zadovoljevanjem potreb in želja odjemalcev podjetja skrbijo in ohranjajo to medsebojno povezanost med podjetjem in odjemalcem. Glede na to, da živimo v času odprtega trga in globalne ekonomske krize, h kateremu lahko dodamo prenasičenost trga in močno konkurenco na vsakem koraku, je za podjetja bistvenega pomena, da se zaveda ogroženosti ...

  13. Controllable circuit

    DEFF Research Database (Denmark)

    2010-01-01

    A switch-mode power circuit comprises a controllable element and a control unit. The controllable element is configured to control a current in response to a control signal supplied to the controllable element. The control unit is connected to the controllable element and provides the control...

  14. Control rod control device

    International Nuclear Information System (INIS)

    Seiji, Takehiko; Obara, Kohei; Yanagihashi, Kazumi

    1998-01-01

    The present invention provides a device suitable for switching of electric motors for driving each of control rods in a nuclear reactor. Namely, in a control rod controlling device, a plurality of previously allotted electric motors connected in parallel as groups, and electric motors of any selected group are driven. In this case, a voltage of not driving predetermined selected electric motors is at first applied. In this state an electric current supplied to the circuit of predetermined electric motors is detected. Whether integration or failure of a power source and the circuit of the predetermined electric motors are normal or not is judged by the detected electric current supplied. After they are judged normal, the electric motors are driven by a regular voltage. With such procedures, whether the selected circuit is normal or not can be accurately confirmed previously. Since the electric motors are not driven just at the selected time, the control rods are not operated erroneously. (I.S.)

  15. Control Areas

    Data.gov (United States)

    Department of Homeland Security — This feature class represents electric power Control Areas. Control Areas, also known as Balancing Authority Areas, are controlled by Balancing Authorities, who are...

  16. Control of control charts

    NARCIS (Netherlands)

    Sri Nurdiati, S.N.

    2005-01-01

    Although the Shewhart chart is widely used in practice because of its simplicity, applying this control chart to monitor the mean of a process may lead to two types of problems. The first concerns the typically unknown parameters involved in the distribution, while the second concerns the validity

  17. 78 FR 69130 - Importer of Controlled Substances; Notice of Application: Johnson Matthey, Inc.

    Science.gov (United States)

    2013-11-18

    ... Coca Leaves (9040) II Thebaine (9333) II Opium, raw (9600) II Noroxymorphone (9668) II Poppy Straw..., which fall under the authority of section 1002(a)(2)(B) of the Act (21 U.S.C. 952(a)(2)(B)) may, in the...

  18. Resisting Reflexive Control: A Reassessment of Chinas Strategy and A2/AD

    Science.gov (United States)

    2015-04-01

    most prominent advertising sites in the United States. Companies such as Coca - Cola and Prudential have advertised there for years.58 One name that...3. Picture of Xinhua News Agency advertising in Times Square, (Reprinted from Xinhuanet.com, http://news.xinhuanet.com/english2010/ph oto/2011-08

  19. Adaptive Command and Control of Theater Air Power

    Science.gov (United States)

    1997-06-01

    Industries, Citicorp, Coca-Cola, Honda, and Intel corporations practice similar techniques 19 Notes as cited in Thomas Petzinger, Jr., “The Front Lines...before the leap to personal computers and word processors occurred. Finally, anticipation takes place as the stock market adjusts current prices...Leading Marines. January 1995. Fleet Marine Force Manual 1-1. Campaigning. January 1990. Gell-Mann, Murray, The Quark and the Jaguar: Adventures

  20. Dream controller

    Science.gov (United States)

    Cheng, George Shu-Xing; Mulkey, Steven L; Wang, Qiang; Chow, Andrew J

    2013-11-26

    A method and apparatus for intelligently controlling continuous process variables. A Dream Controller comprises an Intelligent Engine mechanism and a number of Model-Free Adaptive (MFA) controllers, each of which is suitable to control a process with specific behaviors. The Intelligent Engine can automatically select the appropriate MFA controller and its parameters so that the Dream Controller can be easily used by people with limited control experience and those who do not have the time to commission, tune, and maintain automatic controllers.

  1. Controllable dose; Dosis controlable

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez R, J T; Anaya M, R A [ININ, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2004-07-01

    With the purpose of eliminating the controversy about the lineal hypothesis without threshold which found the systems of dose limitation of the recommendations of ICRP 26 and 60, at the end of last decade R. Clarke president of the ICRP proposed the concept of Controllable Dose: as the dose or dose sum that an individual receives from a particular source which can be reasonably controllable by means of any means; said concept proposes a change in the philosophy of the radiological protection of its concern by social approaches to an individual focus. In this work a panorama of the foundations is presented, convenient and inconveniences that this proposal has loosened in the international community of the radiological protection, with the purpose of to familiarize to our Mexican community in radiological protection with these new concepts. (Author)

  2. Mosquito Control

    Science.gov (United States)

    ... Labs and Research Centers Contact Us Share Mosquito Control About Mosquitoes General Information Life Cycle Information from ... Repellent that is Right for You DEET Mosquito Control Methods Success in mosquito control: an integrated approach ...

  3. Birth Control

    Science.gov (United States)

    Birth control, also known as contraception, is designed to prevent pregnancy. Birth control methods may work in a number of different ... eggs that could be fertilized. Types include birth control pills, patches, shots, vaginal rings, and emergency contraceptive ...

  4. Neurofuzzy Control

    DEFF Research Database (Denmark)

    Jantzen, Jan

    1997-01-01

    These notes are for a course in fuzzy control and neural networks. By neural networks we more precisely mean neurofuzzy systems rather than pure neural network theory. The notes are an extension to the existing notes on fuzzy control (Jantzen, Fuzzy Control, 1994).......These notes are for a course in fuzzy control and neural networks. By neural networks we more precisely mean neurofuzzy systems rather than pure neural network theory. The notes are an extension to the existing notes on fuzzy control (Jantzen, Fuzzy Control, 1994)....

  5. Control rod position control device

    International Nuclear Information System (INIS)

    Ubukata, Shinji.

    1997-01-01

    The present invention provides a control rod position control device which stores data such as of position signals and driving control rod instruction before and after occurrence of abnormality in control for the control rod position for controlling reactor power and utilized the data effectively for investigating the cause of abnormality. Namely, a plurality of individual control devices have an operation mismatching detection circuit for outputting signals when difference is caused between a driving instruction given to the control rod position control device and the control rod driving means and signals from a detection means for detecting an actual moving amount. A general control device collectively controls the individual control devices. In addition, there is also disposed a position storing circuit for storing position signals at least before and after the occurrence of the control rod operation mismatching. With such procedures, the cause of the abnormality can be determined based on the position signals before and after the occurrence of control rod mismatching operation stored in the position storing circuit. Accordingly, the abnormality cause can be determined to conduct restoration in an early stage. (I.S.)

  6. Control rods

    International Nuclear Information System (INIS)

    Maruyama, Hiromi.

    1984-01-01

    Purpose: To realize effective utilization, cost reduction and weight reduction in neutron absorbing materials. Constitution: Residual amount of neutron absorbing material is averaged between the top end region and other regions of a control rod upon reaching to the control rod working life, by using a single kind of neutron absorbing material and increasing the amount of the neutron absorber material at the top end region of the control rod as compared with that in the other regions. Further, in a case of a control rod having control rod blades such as in a cross-like control rod, the amount of the neutron absorbing material is decreased in the middle portion than in the both end portions of the control rod blade along the transversal direction of the rod, so that the residual amount of the neutron absorbing material is balanced between the central region and both end regions upon reaching the working life of the control rod. (Yoshihara, H.)

  7. Control apparatus

    International Nuclear Information System (INIS)

    Doll, D.W.

    1977-01-01

    A nuclear reactor system is described in which flexible control rods are used to enable insertion of the control rods into guide holes in the core which are distributed over an area larger than the cross section of the control rod penetration in the reactor pressure vessel. Guide tubes extend from the penetration and fan out to the guide holes for guiding the control rods from the penetration to the guide holes

  8. Gaining control

    NARCIS (Netherlands)

    Enden, van der E.; Laan, van der R.

    2008-01-01

    The article reports on the efforts of companies to find a solution for tax risk management, tax accounting and being in control. In trying to find a solution, companies work towards an integrated tax control framework (TCF), a tax risk management and control environment embedded in the internal

  9. Associational control

    DEFF Research Database (Denmark)

    Hvid, Helge Søndergaard; Lund, Henrik Lambrecht; Grosen, Sidsel Lond

    2010-01-01

    Over the last 30 years, the concept of control has had a central position in research into the psychological working environment. Control has been understood as individual autonomy and individual opportunities for development. This article examines whether the concept of control has the same key...

  10. Optimal control

    CERN Document Server

    Aschepkov, Leonid T; Kim, Taekyun; Agarwal, Ravi P

    2016-01-01

    This book is based on lectures from a one-year course at the Far Eastern Federal University (Vladivostok, Russia) as well as on workshops on optimal control offered to students at various mathematical departments at the university level. The main themes of the theory of linear and nonlinear systems are considered, including the basic problem of establishing the necessary and sufficient conditions of optimal processes. In the first part of the course, the theory of linear control systems is constructed on the basis of the separation theorem and the concept of a reachability set. The authors prove the closure of a reachability set in the class of piecewise continuous controls, and the problems of controllability, observability, identification, performance and terminal control are also considered. The second part of the course is devoted to nonlinear control systems. Using the method of variations and the Lagrange multipliers rule of nonlinear problems, the authors prove the Pontryagin maximum principle for prob...

  11. The Political Economy of Counterdrug Policy: The Case of Bolivia, 1997-2006

    Science.gov (United States)

    2007-12-01

    Economia de la Coca,” Comision Inter-americana para el Control del Abuso de Drogas (Inter-American Drug Abuse Control Commission), 6. available from http...this was a frightening thought because, if Mexico , for example, which has more established institutions and legal system than Bolivia, was having a...Penguin Group, Inc) 1988. “Sustituyendo La Economia de la Coca,” Comision Interamericana para el Control del Abuso de Drogas (Inter-American

  12. Taking Control

    Centers for Disease Control (CDC) Podcasts

    2007-11-01

    This podcast gives action steps and reasons to control diabetes.  Created: 11/1/2007 by National Diabetes Education Program (NDEP), a joint program of the Centers for Disease Control and Prevention and the National Institutes of Health.   Date Released: 11/2/2007.

  13. Control Theory.

    Science.gov (United States)

    Toso, Robert B.

    2000-01-01

    Inspired by William Glasser's Reality Therapy ideas, Control Theory (CT) is a disciplinary approach that stresses people's ability to control only their own behavior, based on internal motivations to satisfy five basic needs. At one North Dakota high school, CT-trained teachers are the program's best recruiters. (MLH)

  14. CONTROL ROD

    Science.gov (United States)

    Walker, D.E.; Matras, S.

    1963-04-30

    This patent shows a method of making a fuel or control rod for a nuclear reactor. Fuel or control material is placed within a tube and plugs of porous metal wool are inserted at both ends. The metal wool is then compacted and the tube compressed around it as by swaging, thereby making the plugs liquid- impervious but gas-pervious. (AEC)

  15. Birth Control

    Science.gov (United States)

    ... even if you aren’t going for birth control. What doesn’t work to prevent pregnancy? top It’s ... and taking care of a baby’s many needs. What if I need birth control in an emergency? top Emergency contraception (EC) is ...

  16. Integrated controls

    International Nuclear Information System (INIS)

    Hollaway, F.W.

    1985-01-01

    During 1984, all portions of the Nova control system that were necessary for the support of laser activation and completion of the Nova project were finished and placed in service on time. The Nova control system has been unique in providing, on schedule, the capabilities required in the central control room and in various local control areas throughout the facility. The ambitious goal of deploying this system early enough to use it as an aid in the activation of the laser was accomplished; thus the control system made a major contribution to the completion of Nova activation on schedule. Support and enhancement activities continued during the year on the VAX computer systems, central control room, operator consoles and displays, Novanet data communications network, system-level software for both the VAX and LSI-11 computers, Praxis control system computer language, software management tools, and the development system, which includes office terminals. Computational support was also supplied for a wide variety of test fixtures required by the optical and mechanical subsystems. Significant new advancements were made in four areas in integrated controls this year: the integration software (which includes the shot scheduler), the Praxis language, software quality assurance audit, and software development and data handling. A description of the accomplishments in each of these areas follows

  17. Controlling Hypertension

    Centers for Disease Control (CDC) Podcasts

    A recent study found an increase in self-reported high blood pressure among U.S. adults, and an increase in the use of medications to control high blood pressure. This podcast discusses the importance of controlling high blood pressure.

  18. Experiencing control

    NARCIS (Netherlands)

    Monaci, G.; Braspenning, R.A.C.; Meerbeek, B.W.; Bingley, P.; Rajagopalan, R.; Triki, M.

    2009-01-01

    This report describes the activities carried out in the first part of the Experiencing Control project (2008-324). The guiding idea of the project is to make control part of the experience, exploring new interaction solutions for complex, engaging interactions with Philips devices in the living

  19. Control rod

    International Nuclear Information System (INIS)

    Kawakami, Kazuo; Shimoshige, Takanori; Nishimura, Akira

    1979-01-01

    Purpose: A control rod has been developed, which provided a plurality of through-holes in the vicinity of the sheath fitting position, in order to flatten burn-up, of fuel rods in positions confronting a control rod. Thereby to facilitate the manufacture of the control rods and prevent fuel rod failures. Constitution: A plurality of through-holes are formed in the vicinity of the sheath fitting position of a central support rod to which a sheath for the control rod is fitted. These through-holes are arranged in the axial direction of the central support rod. Accordingly, burn-up of fuel rods confronting the control rods can be reduced by through-holes and fuel rod failures can be prevented. (Yoshino, Y.)

  20. Describing control

    International Nuclear Information System (INIS)

    Fouet, J.M.; Starynkevitch, B.

    1987-01-01

    Incremental development and maintenance of large systems imply that control be clearly separated from knowledge. Finding efficient control for a given class of knowledge is itself a matter of expertise, to which knowledge-based methods may and should be applied. We present here two attempts at building root systems that may later be tuned by knowledge engineers, using the semantics of each particular application. These systems are given heuristics in a declarative manner, which they use to control the application of heuristics. Eventually, some heuristics may be used to compile others (or themselves) into efficient pieces of programmed code

  1. Drug Control

    Science.gov (United States)

    Leviton, Harvey S.

    1975-01-01

    This article attempts to assemble pertinent information about the drug problem, particularily marihuana. It also focuses on the need for an educational program for drug control with the public schools as the main arena. (Author/HMV)

  2. Institutional Controls

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset consists of institutional control data from multiple Superfund sites in U.S. EPA Region 8. These data were acquired from multiple sources at different...

  3. LEED Platin for Coca-Cola. Office park at Duesseldorf; LEED Platin fuer Coca-Cola. Bueropark Ratingen Ost bei Duesseldorf

    Energy Technology Data Exchange (ETDEWEB)

    Meinig, Melanie

    2011-07-01

    The current trend confirms that building-owners and investors more and more have to offer certified real estates in order to be marketable. Whether a purely economic thought or real impetus: the result serves the environment. On the former industrial site Balke-Duerr in Ratingen near Dusseldorf, RKW Rhode Kellermann Wawrowsky GmbH and Co. KG (Duesseldorf, Federal Republic of Germany) has constructed a new building complex which impresses through its sustainable approach. One of the main themes was the integral comprehensive planning.

  4. Control rooms

    International Nuclear Information System (INIS)

    Preuss, W.

    1990-01-01

    The current state of knowledge about screen systems for application in traffic (e.g., flight control), process control, and production is presented. The 29 lectures, 5 of which relate to aviation, deal with the optimization of the man-machine interface with respect to unusual operating situations and adequate presentation and action methods on the basis of taks and event analyses integrating the users. (DG) [de

  5. Controlling Hypertension

    Centers for Disease Control (CDC) Podcasts

    Hypertension, or high blood pressure, affects one third of U.S. adults and is a leading cause of heart disease and stroke. A recent study found an increase in self-reported high blood pressure among U.S. adults, and an increase in the use of medications to control high blood pressure. In this podcast, Dr. Fleetwood Loustalot discusses the importance of controlling high blood pressure.

  6. Role of triple fixed combination valsartan, amlodipine and hydrochlorothiazide in controlling blood pressure

    Directory of Open Access Journals (Sweden)

    Monica Doménech

    2010-04-01

    Full Text Available Monica Doménech, Antonio CocaHypertension Unit, Department of Internal Medicine, Institute of Internal Medicine and Dermatology, Hospital Clinic (IDIBAPS, University of Barcelona, SpainAbstract: Hypertension is one of the main risk factors for the development of cardiovascular diseases and the search for new therapeutic strategies aimed at optimizing its control remains an ongoing research and clinical challenge. In recent years, there has been a marked increase in the use of combinations of antihypertensive drugs with complementary mechanisms of action, with the aims of reducing blood pressure levels more rapidly and vigorously than strategies employing monotherapy and improving treatment compliance and adhesion. Therefore, as recommended by the 2009 reappraisal of the European Society of Hypertension/European Society of Cardiology Guidelines, the use of a triple combination that combines a calcium channel blocker, an angiotensin II receptor blocker and a thiazide diuretic seems a reasonable and efficacious combination for the management of hypertensive patients with moderate, high or very high risk. This article reviews the clinical trials carried out with the fixed combination of amlodipine/valsartan/hydrochlorothiazide at the doses recommended for each drug in monotherapy. The data show that this combination achieved greater reductions in mean sitting diastolic and systolic blood pressure than amlodipine, valsartan or hydrochlorothiazide in monotherapy, with favorable pharmacodynamic and pharmacokinetic profiles. The triple combination at high single doses should be used with caution in elderly patients and those with renal or liver failure. Although the tolerability and safety of the triple combination are good, the mostfrequently reported adverse effects were peripheral edema, headache and dizziness. Analytical alterations were consistent with the already-known biochemical effects of amlodipine, valsartan or hydrochlorothiazide in

  7. Control rods

    International Nuclear Information System (INIS)

    Koga, Isao; Masuoka, Ryuzo.

    1979-01-01

    Purpose: To prevent fuel element failures during power conditioning by removing liquid absorbents in poison tubes of control rods in a fast power up step and extracting control rods to slightly increase power in a medium power up step. Constitution: A plurality of poison tubes are disposed in a coaxial or plate-like arrangement and divided into a region capable of compensating the reactivity from the initial state at low temperature to 40% power operation and a region capable of compensating the reactivity in the power up above 40% power operation. Soluble poisons are used as absorbers in the poison tubes corresponding to above 40% power operation and they are adapted to be removed independently from the driving of control rods. The poison tubes filled with the soluble absorbers are responsible for the changes in the reactivity from the initial state at low temperature to the medium power region and the reactivity control is conducted by the elimination of liquid absorbers from the poison tubes. In the succeeding slight power up region above the medium power, power up is proceeding by extracting the control rods having remaining poison tubes filled with solid or liquid absorbers. (Seki, T.)

  8. Losing control

    DEFF Research Database (Denmark)

    Leppink, Eric; Odlaug, Brian Lawrence; Lust, Katherine

    2014-01-01

    picking disorder). CONCLUSIONS: Assaultive behavior appears fairly common among college students and is associated with symptoms of depression and impulse control disorders. Significant distress and diminished behavioral control suggest that assaultive behaviors may often be associated with significant......OBJECTIVE: Assaultive behaviors are common among young people and have been associated with a range of other unhealthy, impulsive behaviors such as substance use and problem gambling. This study sought to determine the predictive ability of single assaultive incidents for impulse control disorders......, an association that has yet to be examined, especially in young adults. METHODS: The authors conducted a university-wide email survey in the spring of 2011 on 6000 university students. The survey examined assaultive behavior and associated mental health variables (using a clinically validated screening...

  9. Coordinating controls

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1986-07-15

    While physics Laboratories are having to absorb cuts in resources, the machines they rely on are becoming more and more complex, requiring increasingly sophisticated systems. Rather than being a resourceful engineer or physicist able to timber together solutions in his 'backyard', the modern controls specialist has become a professional in his own right. Because of possible conflicts between increasing sophistication on one hand and scarcer resources on the other, there was felt a need for more contacts among controls specialists to exchange experiences, coordinate development and discuss 'family problems', away from meetings where the main interest is on experimental physics.

  10. Helicopter Controllability

    Science.gov (United States)

    1989-09-01

    106 3. Program CC Systems Technology, Inc. (STI) of Hawthorne, CA., develops and markets PC control system analysis and design software including...is marketed in Palo Alto, Ca., by Applied i and can be used for both linear and non- linear control system analysis. Using TUTSIM involves developing...gravity centroid ( ucg ) can be calculated as 112 n m pi - 2 zi acg n i (7-5) where pi = poles zi = zeroes n = number of poles m = number of zeroes If K

  11. Coordinating controls

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    While physics Laboratories are having to absorb cuts in resources, the machines they rely on are becoming more and more complex, requiring increasingly sophisticated systems. Rather than being a resourceful engineer or physicist able to timber together solutions in his 'backyard', the modern controls specialist has become a professional in his own right. Because of possible conflicts between increasing sophistication on one hand and scarcer resources on the other, there was felt a need for more contacts among controls specialists to exchange experiences, coordinate development and discuss 'family problems', away from meetings where the main interest is on experimental physics

  12. Topology control

    NARCIS (Netherlands)

    Buchin, K.; Buchin, M.; Wagner, D.; Wattenhofer, R.

    2007-01-01

    Information between two nodes in a network is sent based on the network topology, the structure of links connecting pairs of nodes of a network. The task of topology control is to choose a connecting subset from all possible links such that the overall network performance is good. For instance, a

  13. Control mental

    OpenAIRE

    Bueno i Torrens, David, 1965-

    2013-01-01

    La revista especialitzada NeuroReport ha publicat un article que m'ha aportat nous elements de reflexió sobre els mecanismes neurals de control mental que, de forma innata, realitzem les persones com a part de la nostra vida social.

  14. Control rod

    International Nuclear Information System (INIS)

    Igarashi, Takao; Yoshimoto, Yuichiro; Sugawara, Satoshi; Fukumoto, Takashi; Endo, Zen-ichiro; Saito, Shozo; Shinpo, Katsutoshi; Nishimura, Akira; Ozawa, Michihiro

    1988-01-01

    Purpose: To provide a sufficient shutdown margin upon reactor shutdown, prevent sheath deformation without decreasing neutron absorbents and prevent impact shocks exerted to structural materials. Constitution: The control rod of the present invention comprises a neutron absorption region, a sheath deformation means attached to the side wall and means for restricting and supporting axial movement of the neutron absorbent rod. Then, the amount of absorptive nuclei chained absorbents in the lower region is reduced than that in the upper region. In this way, effective neutron absorbing performance can be obtained relative to the neutron importance distribution during reactor shutdown. In addition, since the operationability is improved by reducing the weight of the control rod and the absorptive nuclei chained neutron abosrbers are used, mechanical nuclear life of the control rod can be increased. Thus, it is possible to prevent the outward deformation of the sheath, as well as prevent collision between the neutron absorber rod and the structural material on the side of inserting the control rod generated upon reactor scram by a simple structure. (Kamimura, M.)

  15. Sistema de gestão ambiental como suporte na identificação dos custos com controle, preservação e recuperação do meio ambiente

    Directory of Open Access Journals (Sweden)

    Vera Sirlene Leonardo

    2013-12-01

    Full Text Available Tendo em vista que a adequação ambiental gera um custo adicional que pode ser identificado a partir da implantação de sistemas de gestão ambiental, esta pesquisa tem como objetivo mapear os custos relativos ao controle, à preservação e recuperação do meio ambiente a partir do Sistema de Gestão Ambiental (SGA implantado. A pesquisa descritiva foi desenvolvida por meio de estudo de caso realizada em uma empresa fabricante dos produtos Coca-Cola, pois este é um dos setores nos quais a internalização da variável ambiental é de grande relevância, devido à grande competitividade nos mercados globalizados. As informações foram coletadas por meio de questionários e da entrevista semiestruturada, e os resultados mostraram que a identificação e o registro dos custos ambientais estão apoiados no SGA implantado. Conclui-se que, no sistema SAP, as contas representativas dos custos de controle, preservação e recuperação da cadeia produtiva estão classificadas no centro de custos com os demais custos indiretos de fabricação e estão incorporados ao produto final. São custos com programa de qualificação de fornecedores e funcionários; controle da fuligem; tratamento de efluentes; destinação de resíduos industriais; recuperação de água, de filtros de carvão, areia e rinser; investigação da contaminação em solo; e teste e medição dos níveis de contaminação - Due Dilligence de terrenos.

  16. COPD - control drugs

    Science.gov (United States)

    Chronic obstructive pulmonary disease - control drugs; Bronchodilators - COPD - control drugs; Beta agonist inhaler - COPD - control drugs; Anticholinergic inhaler - COPD - control drugs; Long-acting inhaler - COPD - control drugs; ...

  17. Environmental controls

    International Nuclear Information System (INIS)

    Brown, S.

    1996-01-01

    Members of the public are exposed to environmental radiations from a variety of sources. In terms of average dose received the major component is from natural sources of radiation for which there is little or no scope to reduce exposure. Where such opportunities do exist, in those homes with high radon concentrations, the householders tend to ignore the risks despite the availability of comparatively straightforward and inexpensive remediation measures. By comparison there is significant public concern about radioactive waste management and the disposal and discharge of radioactivity to the environment despite strict environmental controls. This paper describes the controls and the wider policy context for radioactive waste management following a major review of policy last year. (author)

  18. Controllable dose

    International Nuclear Information System (INIS)

    Alvarez R, J.T.; Anaya M, R.A.

    2004-01-01

    With the purpose of eliminating the controversy about the lineal hypothesis without threshold which found the systems of dose limitation of the recommendations of ICRP 26 and 60, at the end of last decade R. Clarke president of the ICRP proposed the concept of Controllable Dose: as the dose or dose sum that an individual receives from a particular source which can be reasonably controllable by means of any means; said concept proposes a change in the philosophy of the radiological protection of its concern by social approaches to an individual focus. In this work a panorama of the foundations is presented, convenient and inconveniences that this proposal has loosened in the international community of the radiological protection, with the purpose of to familiarize to our Mexican community in radiological protection with these new concepts. (Author)

  19. quality control

    International Nuclear Information System (INIS)

    Skujina, A.; Purina, S.; Riekstina, D.

    1999-01-01

    The optimal objects: soils, spruce needles and bracken ferns were found for the environmental monitoring in the regions of possible radioactive contamination - near SalaspiIs nuclear reactor and Ignalina nuclear power plant. The determination of Sr-90 was based on the radiochemical separation of Sr-90 (=Y-90) by HDEHP extraction and counting the Cerenkov radiation. The quality control of the results was carried out. (authors)

  20. Vehicle Controller

    Science.gov (United States)

    1985-01-01

    UNISTICK is an airplane-like joystick being developed by Johnson Engineering under NASA and VA sponsorship. It allows a driver to control a vehicle with one hand, and is based upon technology developed for the Apollo Lunar Landings of the 1970's. It allows severely handicapped drivers to operate an automobile or van easily. The system is expected to be in production by March 1986.

  1. Control rod

    International Nuclear Information System (INIS)

    Takeda, Toshikazu; Inoue, Kotaro.

    1979-01-01

    Purpose: To flatten the power distribution in the reactor core without impairing neutron economy by disposing pins containing elements of lower atomic number in the central region of a shroud and loading pins containing depleted uranium in the periphery region thereof. Constitution: The shroud has a layer of pins containing depleted uranium in the peripheral region and a layer of pins containing elements of lower atomic number such as beryllium in the central region. Heat removal from those pins containing depleted uranium and elements of lower atomic number (neutron moderator) is effected by sodium flow outside of the cladding material. The control rod operation is conducted by inserting or extracting the central portion (pins containing elements of lower atomic number such as beryllium) inside of the stainless pipe. Upon extraction of the control rod, the moderator in the central region is removed whereby high speed neutrons are no more deccelerated and the absorption rate to the depleted uranium is decreased. This can flatten the power distribution in the reactore core with the disposition of a plurality of control rods at a better neutron economy as compared with the use of neutron absorber such as boron. (Seki, T.)

  2. Control rod

    International Nuclear Information System (INIS)

    Fukumoto, Takashi; Hirakawa, Hiromasa; Kawashima, Norio; Goto, Yasuyuki.

    1994-01-01

    Neutron absorbers are contained in a tubular member comprising, integrally a tubular portion and four corners disposed at the outer circumference of the tubular portion at every 90deg, to provide a neutron absorbing tube. A plurality of neutron absorbing tubes are arranged in parallel in the lateral direction, and adjacent corners are joined, into a blade to constitute a control rod. Such a control rod has a great structural strength, simple in the structure and relatively light in weight and can contain a great amount of neutron absorbers. Upon formation of the control rod by arranging the blades in a cross-like shape, at least a portion thereof is constituted with short neutron absorbing tubes shorter than the entire length of the blade, and gaps are formed at positions in adjacent in the axial direction. With such a constitution, there is no worry that a wing end of the blade collides against or be abraded with a fuel channel box or a fuel support. Even if fuel channels are vibrated upon scram of the reactor, such as occurrence of earthquakes, it can be inserted to the reactor easily. (N.H.)

  3. Controlled fragmentation

    International Nuclear Information System (INIS)

    Arnold, Werner

    2002-01-01

    Contrary to natural fragmentation, controlled fragmentation offers the possibility to adapt fragment parameters like size and mass to the performance requirements in a very flexible way. Known mechanisms like grooves inside the casing, weaken the structure. This is, however, excluded for applications with high accelerations during launch or piercing requirements for example on a semi armor piercing penetrator. Another method to achieve controlled fragmentation with an additional grid layer is presented with which the required grooves are produced 'just in time' inside the casing during detonation of the high explosive. The process of generating the grooves aided by the grid layer was studied using the hydrocode HULL with respect to varying grid designs and material combinations. Subsequent to this, a large range of these theoretically investigated combinations was contemplated in substantial experimental tests. With an optimised grid design and a suitable material selection, the controlled fragment admits a very flexible adaptation to the set requirements. Additional advantages like the increase of perforation performance or incendiary amplification can be realized with the grid layer

  4. The Role of Security Assistance in the Andean Initiative

    Science.gov (United States)

    1992-01-01

    national values and institutions, and the domestic violence generated by the trade in drugs is all to familiar . President George Bush, in National...of radio reports. One must keep in mind that the use of such a service is not without potential pitfalls. One pitfall is a lack of familiarity with the...monopoly, ENACO ( Empresa Nacional de la Coca) , with two purposes: 1) 53 to control the flow of coca leaves between producers and consumers; and 2) to

  5. Flow Control

    Science.gov (United States)

    2013-04-08

    can be written as â fj (t) =WO tanh( WIx (t)+bI)+bO, (38) where WI , WO are the input and output matrices, respectively, and bI and bO are the input...applications, present on envisioned airborne optical platforms . One of the problems is that all adaptive optical systems rely on mechanically moving some...of successfully controlling the optical aberration due to the flow over the aperture of airborne optical platforms . As outlined above, systems

  6. Control rod

    International Nuclear Information System (INIS)

    Igarashi, Takao; Sugawara, Satoshi; Yoshimoto, Yuichiro; Saito, Shozo; Fukumoto, Takashi.

    1987-01-01

    Purpose: To reduce the weight and thereby obtain satisfactory operationability of control rods by combining absorbing nuclear chain type neutron absorbers and conventional type neutron absorbers in the axial direction of blades. Constitution: Neutron absorber rods and long life type neutron absorber rods are disposed in a tie rod and a sheath. The neutron absorber rod comprises a poison tube made of stainless steels and packed with B 4 C powder. The long life type neutron absorber rod is prepared by packing B-10 enriched boron carbide powder into a hafnium metal rod, hafnium pipe, europium and stainless made poison tube. Since the long life type absorber rod uses HF as the absorbing nuclear chain type neutron absorber, it absorbs neutrons to form new neutron absorbers to increase the nuclear life. (Yoshino, Y.)

  7. Control Valve

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Wayne R.

    2018-03-20

    A control valve includes a first conduit having a first inlet and a first outlet and defining a first passage; a second conduit having a second inlet and a second outlet and defining a second passage, the second conduit extending into the first passage such that the second inlet is located within the first passage; and a valve plate disposed pivotably within the first passage, the valve plate defining a valve plate surface. Pivoting of the valve plate within the first passage varies flow from the first inlet to the first outlet and the valve plate is pivotal between a first position and a second position such that in the first position the valve plate substantially prevents fluid communication between the first passage and the second passage and such that in the second position the valve plate permits fluid communication between the first passage and the second passage.

  8. Control Prenatal

    Directory of Open Access Journals (Sweden)

    P. Susana Aguilera, DRA.

    2014-11-01

    Full Text Available Los principales objetivos del control prenatal son identificar aquellos pacientes de mayor riesgo, con el fin de realizar intervenciones en forma oportuna que permitan prevenir dichos riesgos y así lograr un buen resultado perinatal. Esto se realiza a través de la historia médica y reproductiva de la mujer, el examen físico, la realización de algunos exámenes de laboratorio y exámenes de ultrasonido. Además es importante promover estilos de vida saludables, la suplementación de ácido fólico, una consejería nutricional y educación al respecto.

  9. Custom controls

    Science.gov (United States)

    Butell, Bart

    1996-02-01

    Microsoft's Visual Basic (VB) and Borland's Delphi provide an extremely robust programming environment for delivering multimedia solutions for interactive kiosks, games and titles. Their object oriented use of standard and custom controls enable a user to build extremely powerful applications. A multipurpose, database enabled programming environment that can provide an event driven interface functions as a multimedia kernel. This kernel can provide a variety of authoring solutions (e.g. a timeline based model similar to Macromedia Director or a node authoring model similar to Icon Author). At the heart of the kernel is a set of low level multimedia components providing object oriented interfaces for graphics, audio, video and imaging. Data preparation tools (e.g., layout, palette and Sprite Editors) could be built to manage the media database. The flexible interface for VB allows the construction of an infinite number of user models. The proliferation of these models within a popular, easy to use environment will allow the vast developer segment of 'producer' types to bring their ideas to the market. This is the key to building exciting, content rich multimedia solutions. Microsoft's VB and Borland's Delphi environments combined with multimedia components enable these possibilities.

  10. Control rods

    International Nuclear Information System (INIS)

    Hirukawa, Koji.

    1979-01-01

    Purpose: To ensure the fuel safety by constituting a control rod with a plurality of poison bodies suspended in a cross-like section and shorter length poison bodies made movable and engageable in the gap between each of the above poison bodies thereby maintaining the function of the shorter length poison constant. Constitution: Cross-like supports are secured to the upper and lower parts of a driving shaft journaled in a sheath and poison bodies composed of neutron absorber poisons of a large thermal neutron absorption cross section and neutron absorber poison tubes for containing them are suspended from the supports. A movable cross-like support is mounted slidably at its base to the lower part of the driving shaft and poison bodies shorter than the above poison bodies and composed of neutron absorber poisons having a greater absorption cross section at the neutron energy region higher than thermal neutron region and neutron poison tubes for containing them are suspended to the movable support at the position capable of engaging in the gap between each of the poison bodies. (Kawakami, Y.)

  11. Pepsi kerkib Coca-Cola varjust / Andrew Ward ; tõlk. Erik Aru

    Index Scriptorium Estoniae

    Ward, Andrew

    2005-01-01

    Firma PepsiCo edust viimastel aastatel. Autori sõnul on suurim firma ees seisev väljakutse Põhja-Ameerika ja Lääne-Euroopa tarbija üha kasvav mure ülekaalu pärast, firma juht Steve Reinemund näeb selles firmale pigem võimalusi kui ohtu. Firma on USA-s kasutusele võtnud märgisüsteemi, et näidata, millised tooted on tervislikumad. Diagrammid: Kasumiallikad; Turuliidrid. Lisa: Vastasseis

  12. Piip ja Tuut ootavad Amarillosse ja Coca-Cola Plazasse perepäevale

    Index Scriptorium Estoniae

    2004-01-01

    Kord kuus, septembrist 2004 kuni 2005.a. maini korraldatavatest perepäevadest. C-C Plazas on perepäevade ajal kavas eriprogramm ja enne või pärast filmi on pered oodatud Viru hotelli restorani Amarillo, kus kavas spetsiaalne lasteprogramm klounidelt Piip ja Tuut

  13. Coca-Cola's Global Lessons: From Education for Corporate Globalization to Education for Global Justice

    Science.gov (United States)

    Saltman, Kenneth J.

    2004-01-01

    Many critics do censure marketers of junk food for their part in inundating every private and public space with health-harming products and slick advertisements. The author focuses on one such company to illustrate how the dangerous influences of corporate ideology on schooling effect much more than public health--they also work to shape the ways…

  14. Deviant Globalization and the Unintended Consequences of Coca Eradication in Colombia

    Science.gov (United States)

    2012-06-01

    Colombian Constitutional Court assumed a central role and had a significant impact on government policy and its response to the needs and...be said that the evidence today suggests that newly constituted forces are slowly emerging whereby legitimate state actors are increasing their...Solutions to Trans-Border Problems?: The Governance of Security and Risk in a post- NAFTA North America (Surrey, England: Ashgate Publishing, 2011), 149

  15. Lokale complicaties van intranasaal cocaïnegebruik: een diagnostische en therapeutische leidraad

    NARCIS (Netherlands)

    van der Poel, Nicolien A.; Schot, Linda J.; Menger, Dirk Jan

    2013-01-01

    In addition to causing nasal septum perforation, cocaine abuse can cause extensive destruction of the osteocartilaginous structures of the nose. The clinical picture can mimic other diseases, such as vasculitis and lymphoma. Here we describe 3 patients with nasal deformities. One patient, a

  16. A Semantic Prosody Analysis of Three Adjective Synonymous Pairs in COCA

    Science.gov (United States)

    Hu, H. C. Marcella

    2015-01-01

    Over the past two decades the concept of semantic prosody has attracted considerable research interest since Sinclair (1991) observed that "many uses of words and phrases show a tendency to occur in a certain semantic environment" (p. 112). Sinclair (2003) also noted that semantic prosody conveys its pragmatic meaning and attitudinal…

  17. Market integration and market structure in the European soft drinks industry: always Coca-Cola?

    OpenAIRE

    Matraves, Catherine

    1999-01-01

    This paper focuses on the question of European integration, considering whether the geographic level at which competition takes place differs across the two major segments of the soft drinks industry: carbonated soft drinks and mineral water. Our evidence shows firms are competing at the European level in both segments. Interestingly, the European market is being integrated through corporate strategy, defined as increased multinationality, rather than increased trade flows. To interpret these...

  18. Anticonvulsiva bij agressie, angststoornissen, psychotische stoornissen en alcohol- en cocaïneonttrekkingsverschijnselen

    NARCIS (Netherlands)

    Barth-Van Veldhuizen, H.G.J.; Reinders, C.; Loonen, A.J.M.; Nolen, W.A.

    2003-01-01

    BACKGROUND: There is an increasing interest in the treatment of psychiatric symptoms with anticonvulsants, especially in the treatment of refractory patients. It is questionable whether or not the efficacy of anticonvulsants as psychotropic drugs is sufficiently verified. AIM: To examine the

  19. The anti-fatigue action of cocaine and habituation to coca in Peru

    OpenAIRE

    Cabieses Molina, Fernando

    2014-01-01

    The concept of fatigue, stressing that this is a likely to be broken down into a series of links, the main process is first established in broad terms: fatigue of central synapses, fatigue neuromuscular plate and fatigue of the muscle fiber. The central synapses fatigue related to movement, is explained by the breakdown of some of the chemical equilibrium states that characterize the function of the neuron. It is located in the synapse and its essence is the inability to transmit nerve impuls...

  20. Merchandising and Licensing to Improve Brand Equity. The Coca-Cola Case

    OpenAIRE

    Albanese, Fabio

    2001-01-01

    Today's markets are characterized by over-supply, intense competitiveness in every sector, increasingly aggressive competition and product and market strategies which are open to imitation. Consequently, the brand, and the values it carries, has become the truly critical competitive factor. In order to compete, each company needs to develop an integrated communication campaign which includes different communication tools, with high impact like advertising, or with specific promotional tasks, ...

  1. Comorbilidad psicopatológica en consumidores de cocaína en tratamiento ambulatorio

    OpenAIRE

    Araos, Pedro; Vergara-Moragues, Esperanza (UNIR); Pedraz, María; Pavón, Francisco Javier; Campos Cloute, Rafael; Calado, Montserrat; Ruiz, Juan Jesús; García-Marchena, Nuria; Gornemann, Isolde; Torrens, Marta; Rodríguez de Fonseca, Fernando

    2014-01-01

    Cocaine addiction is a growing health problem and among its complications highlights the high prevalence of mental disorders co-occurring with abuse and dependence. This psychopathological comorbidity varies according to the time of consumption and the age of the patient. Early detection of psychopathological disorders associated with drug consumption is necessary to optimize health care and to improve the prognosis. The main aim of the present study was to estimate the p...

  2. Uluslararası reklam stratejileri: Azerbaycan’da coca cola örneği

    OpenAIRE

    ZEYNALOV, Eminbey

    2011-01-01

    ÖZET Şirketlerin ulusal pazarları aşarak farklı ülke pazarlarına yöneldikleri bu dönemde, uluslararası reklam stratejilerinin önemi gittikçe artmaktadır. Küresel pazarda rekabet çok yüksek seviyeye çıkmıştır. Bu rekabete dayanmak ve rakipler önünde avantaj sağlamak için en çok kullanılan araç – uluslararası reklamlardır. Şirketlerin uluslararası pazarlara sunacakları reklamların, standardize edilmiş veya uyarlanmış biçimde olması, şirketlerin önemli bir karar alma konusudur. Tarihi bir sü...

  3. Emphysematous gastritis secondary to ingestion of large amounts of Coca Cola.

    Science.gov (United States)

    Hadas-Halpren, I; Hiller, N; Guberman, D

    1993-01-01

    Acute emphysematous gastritis (AEG) is a life-threatening disease in which gas-forming bacteria invade the gastric wall and cause acute inflammation of it. The clinical presentation of the patient with AEG is stormy: severe sepsis which usually leads to an early death. Presented herein is a case of a 16-yr-old boy with AEG. There were no predisposing factors to the condition in this case. Gas invaded the stomach wall and portal venous system, as well as the duodenal wall, a finding that has not been reported previously. The clinical course was very severe but, in contrast to previously reported cases, recovery was very rapid and left no sequelae.

  4. The Governmentality of Childhood Obesity: Coca-Cola, Public Health and Primary Schools

    Science.gov (United States)

    Powell, Darren; Gard, Michael

    2015-01-01

    In this paper, we examine the emergence of what might seem an unexpected policy outcome--a large multinational corporation, frequently blamed for exacerbating childhood obesity, operating as an officially sanctioned driver of anti-obesity initiatives in primary schools across the globe. We draw on Foucault's notion of governmentality to examine…

  5. Radiation control

    International Nuclear Information System (INIS)

    Uchida, Akira

    1981-01-01

    This paper describes on how the condition of radiation level in the ring (storage ring) experimentation room changes corresponding to the operating stage of SOR-ring (synchrotron radiation storage ring), and does not describe on the present radiation control in the SOR facility. The operating stage of SOR is divided into the following five: (1) 307 MeV electron injection, (2) 307 MeV electron storage (used for SOR experiments), (3) energy increase from 307 to 380 MeV, (4) 380 MeV electron storage, (5) re-injection and completion of operation. Gamma and X ray levels are shown when electron beam is injected from the electron synchrotron to the SOR-ring. Two main causes of the high level are reported. Spatial dose rate in storing 307 MeV electrons in also illustrated. This is sufficiently lower than that at electron incidence. The measurement of radiation level at the time of energy increase from 307 to 380 MeV has just started. Since the radiation level in 380 MeV storage, measured at the points about 20 cm apart from the electron orbit, showed several mR/h, the level seems to be negligible at the points where experiments are carried out, 1 m away from the measurement points. The radiation level in electron reinjection and completion of operation may be large during a short period (a few Roentgen) like the time of energy increase. Therefore, the beam shall be re-injected or decreased after confirming that all experimenters have retreated into the predetermined place. (Wakatsuki, Y.)

  6. Active vibration control by robust control techniques

    International Nuclear Information System (INIS)

    Lohar, F.A.

    2001-01-01

    This paper studies active vibration control of multi-degree-of-freedom system. The control techniques considered are LTR, H/sup 2/ and H/sup infinite/. The results show that LTR controls the vibration but its respective settling time is higher than that of the other techniques. The control performance of H/sup infinite/ control is similar to that of H/sup 2/ control in the case of it weighting functions. However, H/sup infinite/ control is superior to H/sup 2/ control with respect to robustness, steady state error and settling time. (author)

  7. Controlling Separation in Turbomachines

    Science.gov (United States)

    Evans, Simon; Himmel, Christoph; Power, Bronwyn; Wakelam, Christian; Xu, Liping; Hynes, Tom; Hodson, Howard

    2010-01-01

    Four examples of flow control: 1) Passive control of LP turbine blades (Laminar separation control). 2) Aspiration of a conventional axial compressor blade (Turbulent separation control). 3) Compressor blade designed for aspiration (Turbulent separation control). 4.Control of intakes in crosswinds (Turbulent separation control).

  8. Control panel for CMC 8080 crate controller

    International Nuclear Information System (INIS)

    Masayuki Inokuchi

    1978-01-01

    The main features of Control Panel for CAMAC Crate Controller CMC 8080 are described. The control panel can be directly connected with CRATE CONTROLLER's front panel connector with a 50 lines cable without any changes in CMC 8080 system circuits. (author)

  9. Uniting Control Lyapunov and Control Barrier Functions

    NARCIS (Netherlands)

    Romdlony, Zakiyullah; Jayawardhana, Bayu

    2014-01-01

    In this paper, we propose a nonlinear control design for solving the problem of stabilization with guaranteed safety. The design is based on the merging of a Control Lyapunov Function and a Control Barrier Function. The proposed control method allows us to combine the design of a stabilizer based on

  10. Interaction between production control and quality control

    NARCIS (Netherlands)

    Bij, van der J.D.; Ekert, van J.H.W.

    1999-01-01

    Describes a qualitative study on interaction between systems for production control and quality control within industrial organisations. Production control and quality control interact in a sense. Good performance for one aspect often influences or frustrates the performance of the other. As far as

  11. Control heeft vele gezichten

    NARCIS (Netherlands)

    Steens, H.B.A.

    The editorial summarizes several perspectives of control, including the control conducted by supervisors, control based on classical budgeting, control by analytics, et cetera, and relates these angles to the papers in this issue of the journal.

  12. Hierarchical Control of Thermostatically Controller Loads for Primary Frequency Control

    DEFF Research Database (Denmark)

    Zhao, Haoran; Wu, Qiuwei; Huang, Shaojun

    2016-01-01

    reserve references. At the middle level, distribution substations estimate the available power of TCLs based on the aggregated bin model, and dispatch control signals to individual TCLs. At the local level, a supplementary frequency control loop is implemented at the local controller, which makes TCLs...... respond to the frequency event autonomously. Case studies show that the proposed controller can efficiently respond to frequency events and fulfill the requirement specified by the system operator. The users’ comforts are not compromised and the short cycling of TCLs is largely reduced. Due...... to the autonomous control, the communication requirement is minimized....

  13. Incoherent control of locally controllable quantum systems

    International Nuclear Information System (INIS)

    Dong Daoyi; Zhang Chenbin; Rabitz, Herschel; Pechen, Alexander; Tarn, T.-J.

    2008-01-01

    An incoherent control scheme for state control of locally controllable quantum systems is proposed. This scheme includes three steps: (1) amplitude amplification of the initial state by a suitable unitary transformation, (2) projective measurement of the amplified state, and (3) final optimization by a unitary controlled transformation. The first step increases the amplitudes of some desired eigenstates and the corresponding probability of observing these eigenstates, the second step projects, with high probability, the amplified state into a desired eigenstate, and the last step steers this eigenstate into the target state. Within this scheme, two control algorithms are presented for two classes of quantum systems. As an example, the incoherent control scheme is applied to the control of a hydrogen atom by an external field. The results support the suggestion that projective measurements can serve as an effective control and local controllability information can be used to design control laws for quantum systems. Thus, this scheme establishes a subtle connection between control design and controllability analysis of quantum systems and provides an effective engineering approach in controlling quantum systems with partial controllability information.

  14. Covariance upperbound controllers for networked control systems

    International Nuclear Information System (INIS)

    Ko, Sang Ho

    2012-01-01

    This paper deals with designing covariance upperbound controllers for a linear system that can be used in a networked control environment in which control laws are calculated in a remote controller and transmitted through a shared communication link to the plant. In order to compensate for possible packet losses during the transmission, two different techniques are often employed: the zero-input and the hold-input strategy. These use zero input and the latest control input, respectively, when a packet is lost. For each strategy, we synthesize a class of output covariance upperbound controllers for a given covariance upperbound and a packet loss probability. Existence conditions of the covariance upperbound controller are also provided for each strategy. Through numerical examples, performance of the two strategies is compared in terms of feasibility of implementing the controllers

  15. Output Control Using Feedforward And Cascade Controllers

    Science.gov (United States)

    Seraji, Homayoun

    1990-01-01

    Report presents theoretical study of open-loop control elements in single-input, single-output linear system. Focus on output-control (servomechanism) problem, in which objective is to find control scheme that causes output to track certain command inputs and to reject certain disturbance inputs in steady state. Report closes with brief discussion of characteristics and relative merits of feedforward, cascade, and feedback controllers and combinations thereof.

  16. Controlling chaotic systems via nonlinear feedback control

    International Nuclear Information System (INIS)

    Park, Ju H.

    2005-01-01

    In this article, a new method to control chaotic systems is proposed. Using Lyapunov method, we design a nonlinear feedback controller to make the controlled system be stabilized. A numerical example is given to illuminate the design procedure and advantage of the result derived

  17. Personal exposure control system

    International Nuclear Information System (INIS)

    Tanabe, Ken-ichi; Akashi, Michio

    1994-01-01

    Nuclear power stations are under strict radiation control. Exposure control for nuclear workers is the most important operation, and so carefully thought out measures are taken. This paper introduces Fuji Electric's personal exposure control system that meets strict exposure control and rationalizes control operations. The system has a merit that it can provide required information in an optimum form using the interconnection of a super minicomputer and exposure control facilities and realizes sophisticated exposure control operations. (author)

  18. Introduction of digital control

    International Nuclear Information System (INIS)

    Kim, Sang Jin

    1988-01-01

    This book is one of mechatronics series. It deals with digital control, which includes what is digital control?, display way of control system, output of primary system, secondary system like example of system and display way of the system, stabilizing of control system such as method to decide stability and system out of control, displaying equation of state into vector, good control such as the right characteristic, transient behavior and design of position control system using DC servo motor.

  19. Solid state controller three axes controller

    Science.gov (United States)

    Bailey, C. L., Jr. (Inventor)

    1973-01-01

    The reported flight controller features a handle grip which is mounted on a longitudinally extending control element. The handle grip is pivotally mounted on the control element about a pitch axis which is perpendicular to the longitudinal axis through the control element. The pivotal mounting includes a resilient force mounting mechanism which centers the grip relative to the control element. Rotation of the handle grip produces a direct rotation of a transducer element in a transducer which provides an electrical indication of the rotative movement about three mutually perpendicular axes.

  20. PID control with robust disturbance feedback control

    DEFF Research Database (Denmark)

    Kawai, Fukiko; Vinther, Kasper; Andersen, Palle

    2015-01-01

    Disturbance Feedback Control (DFC) is a technique, originally proposed by Fuji Electric, for augmenting existing control systems with an extra feedback for attenuation of disturbances and model errors. In this work, we analyze the robustness and performance of a PID-based control system with DFC...... and performance (if such gains exist). Finally, two different simulation case studies are evaluated and compared. Our numerical studies indicate that better performance can be achieved with the proposed method compared with a conservatively tuned PID controller and comparable performance can be achieved when...... compared with an H-infinity controller....

  1. Organizational Control: Two Functions

    Science.gov (United States)

    Ouchi, William G.; Maguire, Mary Ann

    1975-01-01

    Distinguishes between two modes of organizational control, personal surveillance (behavior control) and the measurement of outputs (output control). Output control occurs in response to a manager's need to provide legitimate evidence of performance, while behavior control is exerted when means-ends relations are known and appropriate instruction…

  2. Structural Pest Control.

    Science.gov (United States)

    Kahn, M. S.; Hoffman, W. M.

    This manual is designed for those who seek certification as pesticide applicators for industrial, institutional, structural, and health-related pest control. It is divided into six sections covering general pest control, wood-destroying organisms, bird control, fumigation, rodent control, and industrial weed control. The manual gives information…

  3. BSF control system

    International Nuclear Information System (INIS)

    Irie, Y.; Ishii, K.; Ninomiya, S.; Sasaki, H.; Sakai, I.

    1982-08-01

    The booster synchrotron utilization facility (BSF) is a facility which utilizes the four fifths of available beam pulses from the KEK booster synchrotron. The BSF control system includes the beam line control, interactions with the PS central control room and the experimental facilities, and the access control system. A brief description of the various components in the control system is given. (author)

  4. Motion control report

    CERN Document Server

    2013-01-01

    Please note this is a short discount publication. In today's manufacturing environment, Motion Control plays a major role in virtually every project.The Motion Control Report provides a comprehensive overview of the technology of Motion Control:* Design Considerations* Technologies* Methods to Control Motion* Examples of Motion Control in Systems* A Detailed Vendors List

  5. Integrated Control Using the SOFFT Control Structure

    Science.gov (United States)

    Halyo, Nesim

    1996-01-01

    The need for integrated/constrained control systems has become clearer as advanced aircraft introduced new coupled subsystems such as new propulsion subsystems with thrust vectoring and new aerodynamic designs. In this study, we develop an integrated control design methodology which accomodates constraints among subsystem variables while using the Stochastic Optimal Feedforward/Feedback Control Technique (SOFFT) thus maintaining all the advantages of the SOFFT approach. The Integrated SOFFT Control methodology uses a centralized feedforward control and a constrained feedback control law. The control thus takes advantage of the known coupling among the subsystems while maintaining the identity of subsystems for validation purposes and the simplicity of the feedback law to understand the system response in complicated nonlinear scenarios. The Variable-Gain Output Feedback Control methodology (including constant gain output feedback) is extended to accommodate equality constraints. A gain computation algorithm is developed. The designer can set the cross-gains between two variables or subsystems to zero or another value and optimize the remaining gains subject to the constraint. An integrated control law is designed for a modified F-15 SMTD aircraft model with coupled airframe and propulsion subsystems using the Integrated SOFFT Control methodology to produce a set of desired flying qualities.

  6. ISABELLE control system

    International Nuclear Information System (INIS)

    Humphrey, J.W.; Frankel, R.S.; Niederer, J.A.

    1980-01-01

    Design principles for the Brookhaven ISABELLE control intersecting storage ring accelerator are described. Principal features include a locally networked console and control computer complex, a system wide process data highway, and intelligent local device controllers. Progress to date is summarized

  7. Control Measure Dataset

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EPA Control Measure Dataset is a collection of documents describing air pollution control available to regulated facilities for the control and abatement of air...

  8. Olivo-Cerebellar Controller

    National Research Council Canada - National Science Library

    Bandyopadhyay, Promode R

    2008-01-01

    ...) used in a maneuvering controller or control system of an underwater vehicle. In order to attain the objects described, the present invention provides closed-loop control of multiple inferior olives (IOs...

  9. Birth control pills - combination

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000655.htm Birth control pills - combination To use the sharing features on ... both progestin and estrogen. What Are Combination Birth Control Pills? Birth control pills help keep you from ...

  10. Riot Control Agents

    Science.gov (United States)

    ... Submit What's this? Submit Button Facts About Riot Control Agents Interim document Recommend on Facebook Tweet Share Compartir What riot control agents are Riot control agents (sometimes referred to ...

  11. Essure Permanent Birth Control

    Science.gov (United States)

    ... Prosthetics Essure Permanent Birth Control Essure Permanent Birth Control Share Tweet Linkedin Pin it More sharing options ... Print Essure is a a permanently implanted birth control device for women (female sterilization). Implantation of Essure ...

  12. Wisdom Appliance Control System

    Science.gov (United States)

    Hendrick; Jheng, Jyun-Teng; Tsai, Chen-Chai; Liou, Jia-Wei; Wang, Zhi-Hao; Jong, Gwo-Jia

    2017-07-01

    Intelligent appliances wisdom involves security, home care, convenient and energy saving, but the home automation system is still one of the core unit, and also using micro-processing electronics technology to centralized and control the home electrical products and systems, such as: lighting, television, fan, air conditioning, stereo, it composed of front-controller systems and back-controller panels, user using front-controller to control command, and then through the back-controller to powered the device.

  13. Test Control Center (TCC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Test Control Center (TCC) provides a consolidated facility for planning, coordinating, controlling, monitoring, and analyzing distributed test events. ,The TCC...

  14. A new controllable damper with neuro controller

    International Nuclear Information System (INIS)

    Kobayashi, N.; Kobayashi, H.; Saito, O.; Yokoi, R.; Morishita, S.

    1993-01-01

    A new controllable damper is proposed for suppressing the vibration of the piping system for wide frequency range. Electro-Rheological fluid (ER fluid) is enclosed in the damper casing in place of oil, and the apparent viscosity of ER fluid can be varied by applying electric field strength (E.F.S.), which is controlled by an adaptive neural network controller. The shaking test is conducted about a simplified L-shaped piping model with a prototype controllable damper. The test results show the effectiveness of the presented controllable damper for suppressing very small amplitude vibration of the piping system. Furthermore an application of neural network is discussed to control E.F.S. of the electrode. (author)

  15. Digital control programmer for temperature control

    International Nuclear Information System (INIS)

    Rajore, S.B.; Kumar, S.V.

    1993-01-01

    This report describes a PC based digital control programmer for controlling and programming temperature of a high vacuum resistance heating furnace and the software developed to control power using PID algorithm. It also describes the amplifier specially developed to suit the input requirement of the non-standard W5 thermocouple and the software and hardware protections introduced in the system. (author). 5 refs., 8 figs., 1 appendix

  16. Control and optimal control theories with applications

    CERN Document Server

    Burghes, D N

    2004-01-01

    This sound introduction to classical and modern control theory concentrates on fundamental concepts. Employing the minimum of mathematical elaboration, it investigates the many applications of control theory to varied and important present-day problems, e.g. economic growth, resource depletion, disease epidemics, exploited population, and rocket trajectories. An original feature is the amount of space devoted to the important and fascinating subject of optimal control. The work is divided into two parts. Part one deals with the control of linear time-continuous systems, using both transfer fun

  17. Reactor control device

    International Nuclear Information System (INIS)

    Fukami, Haruo; Morimoto, Yoshinori.

    1981-01-01

    Purpose: To operate a reactor always with safety operation while eliminating the danger of tripping. Constitution: In a reactor control device adapted to detect the process variants of a reactor, control a control rod drive controlling system based on the detected signal to thereby control the driving the control rods, control the reactor power and control the electric power generated from an electric generator by the output from the reactor, detection means is provided for the detection of the electric power from said electric generator, and a compensation device is provided for outputting control rod driving compensation signals to the control rod driving controlling system in accordance with the amount of variation in the detected value. (Seki, T.)

  18. Power control device

    International Nuclear Information System (INIS)

    Fukawa, Naohiro.

    1982-01-01

    Purpose: To alleviate the load of an operator by automatically operating the main controller, the speed controller, etc. of a recirculation control system and safely operating them without erroneous operation for long period of time, thereby improving the efficiency of a plant. Constitution: An electric type hydraulic control device controls loads of a turbine and a generator and outputs a control signal also to the main controller of a recirculation flow rate control system. At this time, the main controller is set at an automatic position, and the speed controller receives a recirculation pump speed signal from the main controller at the automatic position. The speed controller outputs a pump speed control signal to the recirculation pump system, and a reactor generates a power corresponding thereto. When the power control is automatically performed by the recirculation flow rate control, an operator sets a rate of change of the recirculation pump speed and the rate of change of the mean power range monitor at a change rate setting unit. Therefore, the control of the recirculation flow rate under the power control can be substantially entirely automated. (Yoshigara, H.)

  19. Process and apparatus for controlling control rods

    International Nuclear Information System (INIS)

    Gebelin, B.; Couture, R.

    1987-01-01

    This process and apparatus is characterized by 2 methods, for examination of cluster of nuclear control rods. Foucault current analyzer which examines fraction by fraction all the control rods. This examination is made by rotation of the cluster. Doubtful rods are then analysed by ultrasonic probe [fr

  20. Robust control charts in statistical process control

    NARCIS (Netherlands)

    Nazir, H.Z.

    2014-01-01

    The presence of outliers and contaminations in the output of the process highly affects the performance of the design structures of commonly used control charts and hence makes them of less practical use. One of the solutions to deal with this problem is to use control charts which are robust

  1. Try to Control Yourself!

    Science.gov (United States)

    Esque, Timm J.

    1996-01-01

    Conventional management controls employees, but successful management encourages and enables employees to control themselves. Where control resides in an organization can be determined by examining its performance tracking systems. Most are management information systems. The best are owned and used by the employees to control and adjust their own…

  2. Evaluation of Internal Control

    OpenAIRE

    Gheorghe Suciu; Pipu-Nicolae Barsan

    2013-01-01

    Performance is indissolubly tied to control. Performance cannot be obtained without a strong, adequate control, regardless if it is in the public or private sector. Control is one of management’s attributes and it must be organized, implemented and evaluated in every company, regardless of its size. Each person from a company participates to a greater or lesser extent in the control activities.

  3. Programmable dc motor controller

    Science.gov (United States)

    Hopwood, J. E.

    1982-11-01

    A portable programmable dc motor controller, with features not available on commercial instruments was developed for controlling fixtures during welding processes. The controller can be used to drive any dc motor having tachometer feedback and motor requirements not exceeding 30 volts, 3 amperes. Among the controller's features are delayed start time, upslope time, speed, and downslope time.

  4. Exotic biological control agents

    NARCIS (Netherlands)

    Hajek, Ann E.; Hurley, Brett P.; Kenis, Marc; Garnas, Jeffrey R.; Bush, Samantha J.; Wingfield, Michael J.; Lenteren, van Joop C.; Cock, Matthew J.W.

    2016-01-01

    Biological control is a valuable and effective strategy for controlling arthropod pests and has been used extensively against invasive arthropods. As one approach for control of invasives, exotic natural enemies from the native range of a pest are introduced to areas where control is needed.

  5. Optimal decoupling controllers revisited

    Czech Academy of Sciences Publication Activity Database

    Kučera, Vladimír

    2013-01-01

    Roč. 42, č. 1 (2013), s. 1-16 ISSN 0324-8569 R&D Projects: GA TA ČR(CZ) TE01020197 Institutional support: RVO:67985556 Keywords : linear systems * fractional representations * decoupling control lers * stabilizing control lers * optimal control lers Subject RIV: BC - Control Systems Theory

  6. Automatic control systems engineering

    International Nuclear Information System (INIS)

    Shin, Yun Gi

    2004-01-01

    This book gives descriptions of automatic control for electrical electronics, which indicates history of automatic control, Laplace transform, block diagram and signal flow diagram, electrometer, linearization of system, space of situation, state space analysis of electric system, sensor, hydro controlling system, stability, time response of linear dynamic system, conception of root locus, procedure to draw root locus, frequency response, and design of control system.

  7. Catastrophes control problem

    International Nuclear Information System (INIS)

    Velichenko, V.V.

    1994-01-01

    The problem of catastrophe control is discussed. Catastrophe control aims to withdraw responsible engineering constructions out of the catastrophe. The mathematical framework of catastrophes control systems is constructed. It determines the principles of systems filling by the concrete physical contents and, simultaneously, permits to employ modern control methods for the synthesis of optimal withdrawal strategy for protected objects

  8. Adaptive Extremum Control and Wind Turbine Control

    DEFF Research Database (Denmark)

    Ma, Xin

    1997-01-01

    This thesis is divided into two parts, i.e., adaptive extremum control and modelling and control of a wind turbine. The rst part of the thesis deals with the design of adaptive extremum controllers for some processes which have the behaviour that process should have as high e ciency as possible...... in parameters, and thus directly lends itself to parameter estimation and adaptive control. The extremum control law is derived based on static optimization of a performance function. For a process with nonlinearity at output the intermediate signal between the linear part and nonlinear part plays an important....... Firstly, it is assumed that the nonlinear processes can be divided into a dynamic linear part and static nonlinear part. Consequently the processes with input nonlinearity and output nonlinearity are treated separately. With the nonlinearity at the input it is easy to set up a model which is linear...

  9. HYDRAULIC SERVO CONTROL MECHANISM

    Science.gov (United States)

    Hussey, R.B.; Gottsche, M.J. Jr.

    1963-09-17

    A hydraulic servo control mechanism of compact construction and low fluid requirements is described. The mechanism consists of a main hydraulic piston, comprising the drive output, which is connected mechanically for feedback purposes to a servo control piston. A control sleeve having control slots for the system encloses the servo piston, which acts to cover or uncover the slots as a means of controlling the operation of the system. This operation permits only a small amount of fluid to regulate the operation of the mechanism, which, as a result, is compact and relatively light. This mechanism is particuiarly adaptable to the drive and control of control rods in nuclear reactors. (auth)

  10. Precision digital control systems

    Science.gov (United States)

    Vyskub, V. G.; Rozov, B. S.; Savelev, V. I.

    This book is concerned with the characteristics of digital control systems of great accuracy. A classification of such systems is considered along with aspects of stabilization, programmable control applications, digital tracking systems and servomechanisms, and precision systems for the control of a scanning laser beam. Other topics explored are related to systems of proportional control, linear devices and methods for increasing precision, approaches for further decreasing the response time in the case of high-speed operation, possibilities for the implementation of a logical control law, and methods for the study of precision digital control systems. A description is presented of precision automatic control systems which make use of electronic computers, taking into account the existing possibilities for an employment of computers in automatic control systems, approaches and studies required for including a computer in such control systems, and an analysis of the structure of automatic control systems with computers. Attention is also given to functional blocks in the considered systems.

  11. CONTROLLING AND BUSINESS EFFICIENCY

    Directory of Open Access Journals (Sweden)

    Tina Vuko

    2013-02-01

    Full Text Available Managing business successfully in dynamic environment requires effective controlling system. Controlling is the process of defining objectives, planning and management control so that every decision maker can act in accordance with agreed objectives. Controlling function as a separate department contributes business efficiency trough ensuring transparency of business result and business processes. Controlling takes place when manager and controller cooperate. The aim of this paper is to investigate the effectiveness of controlling function (i.e. controlling department in Croatian companies and to address the specific features of the function that contribute significantly to overall business performance. The research is conducted on the sample of companies listed on the Regulated market of the Zagreb Stock Exchange. Survey is used as a method to collect the data regarding the controlling function, while financial data necessary for the research are extracted from the published financial statements. Results of the research indicate that controlling department has positive effects on the business performance.

  12. Undergraduate reactor control experiment

    International Nuclear Information System (INIS)

    Edwards, R.M.; Power, M.A.; Bryan, M.

    1992-01-01

    A sequence of reactor and related experiments has been a central element of a senior-level laboratory course at Pennsylvania State University (Penn State) for more than 20 yr. A new experiment has been developed where the students program and operate a computer controller that manipulates the speed of a secondary control rod to regulate TRIGA reactor power. Elementary feedback control theory is introduced to explain the experiment, which emphasizes the nonlinear aspect of reactor control where power level changes are equivalent to a change in control loop gain. Digital control of nuclear reactors has become more visible at Penn State with the replacement of the original analog-based TRIGA reactor control console with a modern computer-based digital control console. Several TRIGA reactor dynamics experiments, which comprise half of the three-credit laboratory course, lead to the control experiment finale: (a) digital simulation, (b) control rod calibration, (c) reactor pulsing, (d) reactivity oscillator, and (e) reactor noise

  13. Control of Bioprocesses

    DEFF Research Database (Denmark)

    Huusom, Jakob Kjøbsted

    2015-01-01

    The purpose of bioprocess control is to ensure that the plant operates as designed. This chapter presents the fundamental principles for control of biochemical processes. Through examples, the selection of manipulated and controlled variables in the classical reactor configurations is discussed, so...... are control objectives and the challenges in obtaining good control of the bioreactor. The objective of this chapter is to discuss the bioreactor control problems and to highlight some general traits that distinguish operation of bioprocesses from operation of processes in the conventional chemical process...... industries. It also provides a number of typical control loops for different objectives. A brief introduction to the general principles of process control, the PID control algorithm is discussed, and the design and effect of tuning are shown in an example. Finally, a discussion of novel, model-free control...

  14. Foundations Of Fuzzy Control

    DEFF Research Database (Denmark)

    Jantzen, Jan

    The objective of this textbook is to acquire an understanding of the behaviour of fuzzy logic controllers. Under certain conditions a fuzzy controller is equivalent to a proportional-integral-derivative (PID) controller. Using that equivalence as a link, the book applies analysis methods from...... linear and nonlinear control theory. In the linear domain, PID tuning methods and stability analyses are transferred to linear fuzzy controllers. The Nyquist plot shows the robustness of different settings of the fuzzy gain parameters. As a result, a fuzzy controller is guaranteed to perform as well...... as any PID controller. In the nonlinear domain, the stability of four standard control surfaces is analysed by means of describing functions and Nyquist plots. The self-organizing controller (SOC) is shown to be a model reference adaptive controller. There is a possibility that a nonlinear fuzzy PID...

  15. Reactor control device

    International Nuclear Information System (INIS)

    Kameda, Akiyuki.

    1979-01-01

    Purpose: To enable three types of controls, that is, level control, scram control and excess reactivity control required for a reactor by a same mechanism by feeding neutron absorber liquid and pressure control gas to several blind pipes provided in the reactor core. Constitution: A plurality of blind pipes are disposed spaced apart in a reactor core and connected by way of injection pipes to a neutron absorber liquid tank. A pressure regulator is connected to the blind pipes, to which pressure control gas is supplied. The neutron absorber liquid used herein consists of sodium, potassium or their alloy, or mercury as a basic substance incorporated with one or more selected from boron, tantalum, rhenium, europium or their compounds. The level control, scram control and excess reactivity control can be attained by moderating the pressure changes in the pressure control gas or by regulating the fluctuation in the liquid level. (Horiughi, T.)

  16. Applied predictive control

    CERN Document Server

    Sunan, Huang; Heng, Lee Tong

    2002-01-01

    The presence of considerable time delays in the dynamics of many industrial processes, leading to difficult problems in the associated closed-loop control systems, is a well-recognized phenomenon. The performance achievable in conventional feedback control systems can be significantly degraded if an industrial process has a relatively large time delay compared with the dominant time constant. Under these circumstances, advanced predictive control is necessary to improve the performance of the control system significantly. The book is a focused treatment of the subject matter, including the fundamentals and some state-of-the-art developments in the field of predictive control. Three main schemes for advanced predictive control are addressed in this book: • Smith Predictive Control; • Generalised Predictive Control; • a form of predictive control based on Finite Spectrum Assignment. A substantial part of the book addresses application issues in predictive control, providing several interesting case studie...

  17. Control rod drives

    International Nuclear Information System (INIS)

    Nakamura, Akira.

    1984-01-01

    Purpose: To enable to monitor the coupling state between a control rod and a control rod drive. Constitution: After the completion of a control rod withdrawal, a coolant pressure is applied to a control rod drive being adjusted so as to raise only the control rod drive and, in a case where the coupling between the control rod drive and the control rod is detached, the former is elevated till it contacts the control rod and then stopped. The actual stopping position is detected by an actual position detection circuit and compared with a predetermined position stored in a predetermined position detection circuit. If both of the positions are not aligned with each other, it is judged by a judging circuit that the control rod and the control rod drives are not combined. (Sekiya, K.)

  18. TFTR diagnostic vacuum controller

    International Nuclear Information System (INIS)

    Olsen, D.; Persons, R.

    1981-01-01

    The TFTR diagnostic vacuum controller (DVC) provides in conjunction with the Central Instrumentation Control and Data Acquisition System (CICADA), control and monitoring for the pumps, valves and gauges associated with each individual diagnostic vacuum system. There will be approximately 50 systems on TFTR. Two standard versions of the controller (A and B) wil be provided in order to meet the requirements of two diagnostic manifold arrangements. All pump and valve sequencing, as well as protection features, will be implemented by the controller

  19. Trust and controlling

    OpenAIRE

    Bieńkowska Agnieszka; Zabłocka-Kluczka Anna

    2016-01-01

    The purpose of this study is to discuss the trust within and towards an organisation in the context of implementation of controlling therein. In this context the essence of trust and its importance in organisation management was presented, as well as trust in the contemporary management methods and concepts. Controlling as a trust-building factor inside an organisation was pointed out. Especially controlling and control were described. Moreover management by considering deviations in controll...

  20. Arduino based laser control

    OpenAIRE

    Bernal Muñoz, Ferran

    2015-01-01

    ARDUINO is a vey usefull platform for prototypes. In this project ARDUINO will be used for controling a Semiconductor Tuneable Laser. [ANGLÈS] Diode laser for communications control based on an Arduino board. Temperature control implementation. Software and hardware protection for the laser implementation. [CASTELLÀ] Control de un láser de comunicaciones ópticas desde el ordenador utilizando una placa Arduino. Implementación de un control de temperatura y protección software y hardware ...

  1. Pneumatic control technology

    International Nuclear Information System (INIS)

    Tae, Seong Gil; Kim, Won Hoe; Nam, Dae Hyun

    1993-03-01

    This book contains property of pneumatic pressure drive, pneumatic pressure device like air cleaning, pressure control, lubricators, air pressure pipe, kinds and function of pneumatic pressure equipment like pneumatic cylinders, pneumatic motor, flow control valve, direction control valve, design of pneumatic control circuit, pneumatic system design, cause and measurement of pneumatic circuit failure, PLC and pneumatic control like introduction and system application and method of PLC programing.

  2. Control rod drives

    International Nuclear Information System (INIS)

    Hayakawa, Hiroyasu.

    1979-01-01

    Purpose: To enable rapid control in a simple circuit by providing a motor control device having an electric capacity capable of simultaneously driving all of the control rods rapidly only in the inserting direction as well as a motor controlling device capable of fine control for the insertion and extraction at usual operation. Constitution: The control rod drives comprise a first motor control device capable of finely controlling the control rods both in inserting and extracting directions, a second motor control device capable of rapidly driving the control rods only in the inserting direction, and a first motor switching circuit and a second motor switching circuit switched by switches. Upon issue of a rapid insertion instruction for the control rods, the second motor switching circuit is closed by the switch and the second motor control circuit and driving motors are connected. Thus, each of the control rod driving motors is driven at a high speed in the inserting direction to rapidly insert all of the control rods. (Yoshino, Y.)

  3. SODR Memory Control Buffer Control ASIC

    Science.gov (United States)

    Hodson, Robert F.

    1994-01-01

    The Spacecraft Optical Disk Recorder (SODR) is a state of the art mass storage system for future NASA missions requiring high transmission rates and a large capacity storage system. This report covers the design and development of an SODR memory buffer control applications specific integrated circuit (ASIC). The memory buffer control ASIC has two primary functions: (1) buffering data to prevent loss of data during disk access times, (2) converting data formats from a high performance parallel interface format to a small computer systems interface format. Ten 144 p in, 50 MHz CMOS ASIC's were designed, fabricated and tested to implement the memory buffer control function.

  4. Controlling chaos in Internet congestion control model

    International Nuclear Information System (INIS)

    Chen Liang; Wang Xiaofan; Han Zhengzhi

    2004-01-01

    The TCP end-to-end congestion control plus RED router queue management can be modeled as a discrete-time dynamical system, which may create complex bifurcating and chaotic behavior. Based on the basic features of the TCP-RED model, we propose a time-dependent delayed feedback control algorithm to control chaos in the system by perturbing the accessible RED parameter p max . This method is able to stabilized a router queue occupancy at a level without knowing the exact knowledge of the network. Further, we study the situation of the presence of the UDP traffic

  5. Generic device controller for accelerator control systems

    International Nuclear Information System (INIS)

    Mariotti, R.; Buxton, W.; Frankel, R.; Hoff, L.

    1987-01-01

    A new distributed intelligence control system has become operational at the AGS for transport, injection, and acceleration of heavy ions. A brief description of the functionality of the physical devices making up the system is given. An attempt has been made to integrate the devices for accelerator specific interfacing into a standard microprocessor system, namely, the Universal Device Controller (UDC). The main goals for such a generic device controller are to provide: local computing power; flexibility to configure; and real time event handling. The UDC assemblies and software are described

  6. Controlling chaos in Internet congestion control model

    Energy Technology Data Exchange (ETDEWEB)

    Chen Liang E-mail: chenmoon110@yahoo.com.cn; Wang Xiaofan; Han Zhengzhi

    2004-07-01

    The TCP end-to-end congestion control plus RED router queue management can be modeled as a discrete-time dynamical system, which may create complex bifurcating and chaotic behavior. Based on the basic features of the TCP-RED model, we propose a time-dependent delayed feedback control algorithm to control chaos in the system by perturbing the accessible RED parameter p{sub max}. This method is able to stabilized a router queue occupancy at a level without knowing the exact knowledge of the network. Further, we study the situation of the presence of the UDP traffic.

  7. Vehicle Dynamics and Control

    CERN Document Server

    Rajamani, Rajesh

    2012-01-01

    Vehicle Dynamics and Control provides a comprehensive coverage of vehicle control systems and the dynamic models used in the development of these control systems. The control system applications covered in the book include cruise control, adaptive cruise control, ABS, automated lane keeping, automated highway systems, yaw stability control, engine control, passive, active and semi-active suspensions, tire-road friction coefficient estimation, rollover prevention, and hybrid electric vehicle. In developing the dynamic model for each application, an effort is made to both keep the model simple enough for control system design but at the same time rich enough to capture the essential features of the dynamics. A special effort has been made to explain the several different tire models commonly used in literature and to interpret them physically. In the second edition of the book, chapters on roll dynamics, rollover prevention and hybrid electric vehicles have been added, and the chapter on electronic stability co...

  8. Balancing Trust and Control

    DEFF Research Database (Denmark)

    Jagd, Søren

    This paper focuses on the leadership challenge of balancing trust and control. The relation between trust and control has for a long time been a puzzling issue for management researchers. In the paper I first show that there has been a dramatic change in the way the relation between trust...... and control has been conceptualized in trust research. While the relation between trust and control earlier was conceptualized as a more or less stable balance between trust and control, more recent research conceptualizes the relation between trust and control more as a dynamical process that involves...... an ongoing process of balancing the relation between trust and control. Second, taking the departure in the recent conceptualization of the balance between trust and control as an interactive process I discuss the challenges for management in handling this more subtle balancing of trust and control...

  9. CAMAC multipurpose microprocessor controller

    International Nuclear Information System (INIS)

    Belyakova, M.P.; Nemesh, T.; Buj Zoan Chong.

    1978-01-01

    The use of CAMAC controllers in an autonomous system of data acquisition and measurement is considered. The system consists of a control intelligence controller, memory modules, and user modules in the CAMAC standard. The controller and all the modules have an output into the highway and this permits to exchange data among them without using special external cables. To increase the servicing rate, an auxiliary controller which has direct access to memory and controls the user modules, is additionally connected to the data acquisition and measurement system. In this case, the intelligence controller is passive. The system of data acquisition can be realized in the form of a multiple system with branch usage. The controller module width is three units, and the controller incorporates the Intel-8080-type microprocessor and the following interfaces: of CAMAC highways, of interruption, of memory bootstrap, and of data sequence channel

  10. Control rod shutdown system

    International Nuclear Information System (INIS)

    Miyamoto, Yoshiyuki; Higashigawa, Yuichi.

    1996-01-01

    The present invention provides a control rod terminating system in a BWR type nuclear power plant, which stops an induction electric motor as rapidly as possible to terminate the control rods. Namely, the control rod stopping system controls reactor power by inserting/withdrawing control rods into a reactor by driving them by the induction electric motor. The system is provided with a control device for controlling the control rods and a control device for controlling the braking device. The control device outputs a braking operation signal for actuating the braking device during operation of the control rods to stop the operation of the control rods. Further, the braking device has at least two kinds of breaks, namely, a first and a second brakes. The two kinds of brakes are actuated by receiving the brake operation signals at different timings. The brake device is used also for keeping the control rods after the stopping. Even if a stopping torque of each of the breaks is small, different two kinds of brakes are operated at different timings thereby capable of obtaining a large stopping torque as a total. (I.S.)

  11. Plasma position control device

    International Nuclear Information System (INIS)

    Takase, Haruhiko.

    1987-01-01

    Purpose: To conduct position control stably to various plasmas and reduce the burden on the control coil power source. Constitution: Among the proportional, integration and differentiation controls, a proportional-differentiation control section and an integration control section are connected in parallel. Then, a signal switching circuit is disposed to the control signal input section for the proportional-differentiation control section such that either a present position of plasmas or deviation between the present plasma position and an aimed value can be selected as a control signal depending on the control procedures or the state of the plasmas. For instance, if a rapid response is required for the control, the deviation between the present plasma position and the aimed value is selected as the input signal to conduct proportional, integration and differentiation controls. While on the other hand, if it is intended to reduce the burden on the control coil power source, it is adapted such that the control signal inputted to the proportional-differentiation control section itself can select the present plasma position. (Yoshihara, H.)

  12. Control rod assembly

    International Nuclear Information System (INIS)

    Takahashi, Akio.

    1982-01-01

    Purpose: To enable reliable insertion and drops of control rods, as well as insure a sufficient flow rate of coolants flowing through the control rods for attaining satisfactory cooling thereof to enable relexation of thermal stress resulted to rectifying mechanisms or the likes. Constitution: To the outer circumference of a control rod contained vertically movably within a control rod guide tube, resistive members are retractably provided in such a way as to project to close the gap between outer circumference of the control rod and the inner surface of the control rod guide tube upon engagement of a gripper of control rod drives, and retract upon release of the engagement of the gripper. Thus, since the resistive members project to provide a greater resistance to the coolants flowing between them and the control rod guide tube in the normal operation where the gripper is engaged to drive the control rod by the control rod drives, a major part of the coolant flowing into the control rod guide tube flows into the control rod. This enables to cool the control rod effectively and make the temperature distribution uniform for the coolant flowing from the upper end of the control rod guide tube to thereby attain the relaxation of the thermal stress resulted in the rectifying mechanisms or the likes. (Moriyama, K.)

  13. Control rod displacement

    International Nuclear Information System (INIS)

    Nakazato, S.

    1987-01-01

    This patent describes a nuclear reactor including a core, cylindrical control rods, a single support means supporting the control rods from their upper ends in spaced apart positions and movable for displacing the control rods in their longitudinal direction between a first end position in which the control rods are fully inserted into the core and a second end position in which the control rods are retracted from the core, and guide means contacting discrete regions of the outer surface of each control rod at least when the control rods are in the vicinity of the second end position. The control rods are supported by the support means for longitudinal movement without rotation into and out of the core relative to the guide means to thereby cause the outer surface of the control rods to experience wear as a result of sliding contact with the guide means. The support means are so arranged with respect to the core and the guide means that it is incapable of rotation relative to the guide means. The improvement comprises displacement means being operatively coupled to a respective one of the control rods for periodically rotating the control rod in a single angular direction through an angle selected to change the locations on the outer surfaces of the control rods at which the control rods are contacted by the guide means during subsequent longitudinal movement of the control rods

  14. Intelligent control-III: fuzzy control system

    International Nuclear Information System (INIS)

    Nagrial, M.H.

    2004-01-01

    During the last decade or so, fuzzy logic control (FLC) has emerged as one of the most active and fruitful areas of research and development. The applications include industrial process control to medical diagnostic and financial markets. Many consumer products using this technology are available in the market place. FLC is best suited to complex ill-defined processes that can be controlled by a skilled human operator without much knowledge of their underlying dynamics. This lecture will cover the basic architecture and the design methodology of fuzzy logic controllers. FLC will be strongly based on the concepts of fuzzy set theory, introduced in first lecture. Some practical applications will also be discussed and presented. (author)

  15. Control and automation systems

    International Nuclear Information System (INIS)

    Schmidt, R.; Zillich, H.

    1986-01-01

    A survey is given of the development of control and automation systems for energy uses. General remarks about control and automation schemes are followed by a description of modern process control systems along with process control processes as such. After discussing the particular process control requirements of nuclear power plants the paper deals with the reliability and availability of process control systems and refers to computerized simulation processes. The subsequent paragraphs are dedicated to descriptions of the operating floor, ergonomic conditions, existing systems, flue gas desulfurization systems, the electromagnetic influences on digital circuits as well as of light wave uses. (HAG) [de

  16. Electricity sequence control

    International Nuclear Information System (INIS)

    Shin, Heung Ryeol

    2010-03-01

    The contents of the book are introduction of control system, like classification and control signal, introduction of electricity power switch, such as push-button and detection switch sensor for induction type and capacitance type machinery for control, solenoid valve, expression of sequence and type of electricity circuit about using diagram, time chart, marking and term, logic circuit like Yes, No, and, or and equivalence logic, basic electricity circuit, electricity sequence control, added condition, special program control about choice and jump of program, motor control, extra circuit on repeat circuit, pause circuit in a conveyer, safety regulations and rule about classification of electricity disaster and protective device for insulation.

  17. VOC emissions control systems

    International Nuclear Information System (INIS)

    Spessard, J.E.

    1993-01-01

    The air pollution control equipment marketplace offers many competing technologies for controlling emissions of volatile organic compounds (VOC) in air. If any technology was economically and technically superior under all conditions, it would be the only one on the market. In fact, each technology used to control VOCs is superior under some set of conditions. The reasons for choosing one control technology over another are situation-specific. Some general guidelines to VOC control technologies and the situations where each may be appropriate are presented in this article. The control technologies and applications are summarized in a table

  18. Programmable Digital Controller

    Science.gov (United States)

    Wassick, Gregory J.

    2012-01-01

    An existing three-channel analog servo loop controller has been redesigned for piezoelectric-transducer-based (PZT-based) etalon control applications to a digital servo loop controller. This change offers several improvements over the previous analog controller, including software control over proportional-integral-derivative (PID) parameters, inclusion of other data of interest such as temperature and pressure in the control laws, improved ability to compensate for PZT hysteresis and mechanical mount fluctuations, ability to provide pre-programmed scanning and stepping routines, improved user interface, expanded data acquisition, and reduced size, weight, and power.

  19. Robot welding process control

    Science.gov (United States)

    Romine, Peter L.

    1991-01-01

    This final report documents the development and installation of software and hardware for Robotic Welding Process Control. Primary emphasis is on serial communications between the CYRO 750 robotic welder, Heurikon minicomputer running Hunter & Ready VRTX, and an IBM PC/AT, for offline programming and control and closed-loop welding control. The requirements for completion of the implementation of the Rocketdyne weld tracking control are discussed. The procedure for downloading programs from the Intergraph, over the network, is discussed. Conclusions are made on the results of this task, and recommendations are made for efficient implementation of communications, weld process control development, and advanced process control procedures using the Heurikon.

  20. Control system design method

    Science.gov (United States)

    Wilson, David G [Tijeras, NM; Robinett, III, Rush D.

    2012-02-21

    A control system design method and concomitant control system comprising representing a physical apparatus to be controlled as a Hamiltonian system, determining elements of the Hamiltonian system representation which are power generators, power dissipators, and power storage devices, analyzing stability and performance of the Hamiltonian system based on the results of the determining step and determining necessary and sufficient conditions for stability of the Hamiltonian system, creating a stable control system based on the results of the analyzing step, and employing the resulting control system to control the physical apparatus.