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Sample records for erika jriado lembi

  1. Mõistatuslik Erika Roots / Mariam Selge

    Index Scriptorium Estoniae

    Selge, Mariam

    2012-01-01

    1943. aastal Eestist lahkunud Erika Rootsist (neiuna Salis), kes õppis Saksamaal Berliini kunstikõrgkoolis ja Ameerika Ühendriikides Arts Students Leagues kunsti ning National Technical Institut' is tehnilist joonistamist ja töötas disainerina mitmetes firmades, mis projekteerisid ka aatomielektrijaamu

  2. Keemiaõpetajaks pürgija koolipraktika probleeme kooli ja koolitajate vaatevinklist / Liina Karolin-Salu, Erika Jüriado, Lembi Tamm

    Index Scriptorium Estoniae

    Karolin-Salu, Liina

    2003-01-01

    Artiklis püütakse välja tuua pedagoogilise koolipraktika puudusi ja näidata selle täiustamise võimalusi. Tehakse ettepanekud koolipraktika paremaks korraldamiseks vastavalt Tartu Ülikoolis rakendatavale 3+2 õppesüsteemile

  3. The Erika tanker shipwreck, one year later. synthesis; Naufrage du petrolier Erika, un an apres. synthese

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-12-01

    In december 1999 the Erika tanker shipwreck broke along the Brittany coast leading to the most important sea pollution by hydrocarbons, since the Amoco-Cadiz. One year after this accident the Ministry of the territory management and of the environment takes stock on the actions carried on after the shipwreck: the management of the POLMAR fund, the shoreline cleaning, the land and water ecosystems restoration, the wastes storage and processing, the ecological consequences. A special part is devoted to the maritime transport regulations and safety and to the victims compensation. (A.L.B.)

  4. Interview of Erika Lazarova with Borislav Toshev [In Bulgarian

    Directory of Open Access Journals (Sweden)

    E. Lazarova

    2011-12-01

    Full Text Available In 2011 a book entitled “Golden Book of Bulgarian Science” was published (Lazarova, 2011. Many eminent Bulgarian scientists were interviewed about the course of their life and scientific achievements. The editor of “Venets”, Prof. Dr. B.V. Toshev, DSc, University of Sofia, was amongst them. The full text of his interview, where he shares with Doc. Dr. Erika Lazarova his opinion and reflections about science, research and education, is presented in this journal because the role of family, teachers and Belogradchik for creating the future scientist is specially emphasized.

  5. Assessing the damage caused by the oil spill from the tanker Erika; Erika: elements d'evaluation des dommages

    Energy Technology Data Exchange (ETDEWEB)

    Delache, X.; Erhard-Cassegrain, A

    2001-07-01

    In December 1999, France was faced with a large-scale marine and ecological disaster following the accident involving the oil tanker Erika which split in two before sinking off the coast of Brittany (western France). This disaster had significant impacts on the coastal environment, affecting 400 km of shoreline. Very different aspects need to be considered in order to assess the damage caused, for which suitable methodologies must be used. Expenditure incurred on emergency and remedial measures to prepare for the 2000 summer season can easily be identified. The main effect of the disaster was ecological: a wide variety of habitats and species, and in particular many protected areas were affected. In addition, economic activities were seriously disrupted, especially tourism, fishing and shellfish production. However, it is harder to assess the economic losses incurred since a large number of short-term and long-term factors were affected. (author)

  6. Consequences of Erika's wreckage. Risks, environment, society, rehabilitation

    International Nuclear Information System (INIS)

    Beurier, J.; Pouchus, Y.

    2005-01-01

    On December 12, 1999, the wreckage of the Erika tanker ship led to a huge oil spill along the western coast of France. Important means were implemented to fight against the oil pollution and important research means were mobilized by the university of Nantes to establish a medium and long-term diagnosis and status of the consequences of the wreckage on the coastal environments, on the fauna and flora, on men and on the society. A colloquium was organized on January 23-25, 2002, at the university of medicine and pharmacy of Nantes, to present the results of these studies. This book summarizes the content of the presentations given at this colloquium: past experiences, risks and environment (basic data, impacts of petroleum and of hydrocarbons treatment on the coastal environment), problem of the reference state of environments: what should be protected and according to what scientific argument?, risks and society (economic aspects, risks and warranties, experience feedback, rehabilitation approach at the Guerande peninsula). (J.S.)

  7. Evaluation of exposures to petroleum products of the Erika in the depollution zone

    International Nuclear Information System (INIS)

    Blanchard, O.

    2000-03-01

    The petroleum product of the Erika is a fuel oil type number 2, with many toxic compounds. Thus the risk of the people employed for the depollution must be seriously evaluate. This document presents a study realized at the Croisic. The objective was to identify risk situations, provide an advice on the preventive measures implemented and define, if necessary, a control strategy for the most exposed work station. (A.L.B.)

  8. Reading bones / Lembi Lõugas

    Index Scriptorium Estoniae

    Lõugas, Lembi, 1967-

    2011-01-01

    Eesti Teadusfondi projektist "Uute meetodite rakendamine osteo-arheoloogilises uurimuses", 2006-2009. Tallinna Ülikooli Ajaloo Instituudi arheobioloogia ja muinastehnoloogia osakonnas läbi viidud projekti eesmärgiks oli luu-uurimises rakendada rohkem uusi ja kaasaegseid füüsikalisi ja keemilisi meetodeid

  9. Genotoxic activity and induction of biotransformation enzymes in two human cell lines after treatment by Erika fuel extract.

    Science.gov (United States)

    Amat-Bronnert, Agnès; Castegnaro, Marcel; Pfohl-Leszkowicz, Annie

    2007-01-01

    On 12 December 1999, the tanker Erika broke in two parts at about 60km from the Brittany French coasts (Point of Penmarc'h, Sud Finistère, France). About 10,000tonnes of heavy oil fuel were released in the sea. DNA adduct have been detected in fish liver and mussels digestive gland exposed to the Erika oil spill. In order to investigate the mechanism by which Erika fuel extract exhibits genotoxic effects the induction of DNA adducts by an Erika fuel extract have been analysed on two cell lines, human epithelial bronchial cells (WI) and human hepatoma cells. DNA adducts, reflected by a diagonal radioactive zone and individual adducts are detected only in hepatoma cells indicating biotransformation via CYP 1A2 and CYP 1B1. In addition, Erika fuel extract induces some metabolizing enzymes such CYP 1A2, COX2 and 5-LOX, the two later are involved in cancer processes. Formation of leucotrienes B4 (LTB(4)), a mediator playing a role in inflammation, is induced in epithelial bronchial cells. Since inhalation is one of the ways of contamination for human, the above results are important for human health and prevention. Copyright © 2006 Elsevier B.V. All rights reserved.

  10. Kuis saada läbi Siirita? / Mari-Ann Kelam, Erika Salumäe, Sirje Endre

    Index Scriptorium Estoniae

    Kelam, Mari-Ann, 1946-

    2001-01-01

    Riigikogu uude juhatusse ei kuulu ühtegi naist : Keskerakond valis Siiri Oviiri asemele Riigikogu aseesimehe kohale Peeter Kreitzbergi. Naiste osalemisvõimalust poliitikas kommenteerivad Riigikogu naisliikmed Mari-Ann Kelam, Erika Salumäe, Sirje Endre, Jaana Padrik, Viive Rosenberg, Mai Treial, Ivi Eenmaa, Liis Klaar, Liia Hänni, Laine Tarvis

  11. Assessing the damage caused by the oil spill from the tanker Erika

    International Nuclear Information System (INIS)

    Delache, X.; Erhard-Cassegrain, A.

    2001-07-01

    In December 1999, France was faced with a large-scale marine and ecological disaster following the accident involving the oil tanker Erika which split in two before sinking off the coast of Brittany (western France). This disaster had significant impacts on the coastal environment, affecting 400 km of shoreline. Very different aspects need to be considered in order to assess the damage caused, for which suitable methodologies must be used. Expenditure incurred on emergency and remedial measures to prepare for the 2000 summer season can easily be identified. The main effect of the disaster was ecological: a wide variety of habitats and species, and in particular many protected areas were affected. In addition, economic activities were seriously disrupted, especially tourism, fishing and shellfish production. However, it is harder to assess the economic losses incurred since a large number of short-term and long-term factors were affected. (author)

  12. Standardized assessment system in Chile: share of Mario Leyton Soto and Erika Himmel König

    Directory of Open Access Journals (Sweden)

    Jaime CAICEO ESCUDERO

    2016-10-01

    Full Text Available Educational evaluation, as the science of education, began to be developed and applied in Chile only starting from the sixties of the last century. Indeed, several Chilean educators were to his PhD to United States of America in these areas; among them are Mario Leyton and Erika Himmel, who specialized in curriculum and evaluation, through the approaches of Tyler and Bloom. Therefore, both were actively involved in the introduction into the country of two measurement systems: (1 selection for admission to the University, creating a standardized test, the academic aptitude test –paa– which was established from 1967 and remained until 2002 and from 2003 to date was changed to the university selection test –psu–; initially the paa contained only verbal and mathematical aptitude tests; knowledge tests were subsequently added specific (in mathematics, biology, physics, chemistry and Sciences social. (2 the measurement of achievements educational system school, both in basic education and medium from the 1970s with the called initially program of evaluation of educational achievement –per– and, subsequently, with the system of measurement of the quality of the teaching –simce–, which applies from 1988 until today, at the national level and at various levels of the school system: 4.° Basic, 8.° Basic and 2.° Medium, especially with tests of language and communication and mathematics. Both initiatives were directly involved Mario Leyton and Erika Himmel; the first to key positions in the Ministry of Education and the second as academic of the University of Chile and the Catholic University of Chile. Therefore, both have been recognized by the State with the National Prize of Sciences of Education in 2009 and 2011, respectively.

  13. Proses Individuasi Carl Gustav Jung pada Tokoh Erika Kohut dalam Novel Sang Guru Piano Karya Elfriede Jelinek

    Directory of Open Access Journals (Sweden)

    M. Oktavia Vidiyanti

    2007-12-01

    Full Text Available A personality structure that appears in Erika is similar to one of an important part of Carl Gustav Jung psychology. Jung states that personality is a psiko that covers consciousness and unconsciousness. This psiko will develop to be a stable unity. If every system develops in every individual absolutely, so a health and integrated personality will be achieved. That process in Jung is known as a self­ individualized process. The aim of individualism is a self­achievement. Individual is not only as a psiko centre but also as a representation of the whole individual that unites consciousness and unconsciousness. It is like the character "Erika Kohut" in the novel "Sang Guru Piano".

  14. The oil slick of Erika: ecological and eco-toxicological consequences

    International Nuclear Information System (INIS)

    Laubier, L.

    2004-01-01

    In december 1999 the oil tanker Erika loaded with 31.000 tonnes of industrial fuel oil (IFO) sank off the coasts of Brittany (France). 12.400 tonnes of IFO were recovered in the wrecked parts of the tanker and in the sea, 19.000 tonnes were spilled into the environment. The cleaning campaigns that took place in 2000 and 2001 led to the recovery of 240.000 to 280.000 tonnes of contaminated wastes containing 30.000 to 40.000 tonnes of emulsion, which corresponds to the spilled quantity of IFO. About 30 different programs have been implemented to monitor the environmental contamination and to assess the impact of the spilling on the different natural habitats (sea, rocky areas, beaches, sediments,..) and on fauna and flora. The main results show that: -) the development of plants does not seem affected by the oil contamination except in heavily-stricken zones, -) the concentration of HAP (poly-cyclical aromatic hydro-carbons) in plants is decreasing steadily, -) between 64.000 and 125.000 common guillemots died during the first month after the catastrophe, -) sea mammals have not been directly hit by the spilling, -) populations of sea urchins have been decimated and now are recovering. The main difficulty encountered by these programs assessing the impact is the lack of a reliable reference of the state of the different animal and plant populations before the spilling. (A.C.)

  15. Victor and Erika Webnovela: An Innovative Generation @ Audience Engagement Strategy for Prevention.

    Science.gov (United States)

    Andrade, Elizabeth L; Evans, W Douglas; Edberg, Marc C; Cleary, Sean D; Villalba, Ricardo; Batista, Idalina Cubilla

    2015-01-01

    Entertainment-education (E-E) approaches for young audiences continue to evolve in order to keep stride with younger generations' affinity for technology. E-E and novelas have been used with a wide variety of audiences in the United States, in particular hard-to-reach Latino populations, and have demonstrated effectiveness in disseminating culturally relevant prevention information for a wide variety of health-related risk factors and behaviors. This study discusses the formative research and active engagement of Latino youth living in Langley Park, Maryland, for the development and filming of an innovative 6-episode webnovela titled Victor and Erika (V&E). V&E is part of a larger branding strategy of the Adelante Positive Youth Development intervention that seeks to prevent substance abuse, sexual risk, and interpersonal violence among Latino youth; V&E is also an intervention component. The V&E webnovela is a dramatic portrayal of the lives of 2 immigrant Latino teenagers that also disseminates risk prevention messages. The storyline represents the turning the corner (to a better life) theme that underlies the Adelante intervention brand. Formative research was conducted for character development (n = 20) and creative development of the episodes (n = 14). Results of the formative research showed that youth recommended inclusion of the following topics in V&E episodes: sex, unintended pregnancy, fidelity, trust, family dynamics, immigration status, violence, school dropout, respect, home life, and poverty. Detailed character and episode descriptions are provided, and the implications of using the V&E series as a tool for in-person and online engagement of youth and the dissemination of prevention messages are also discussed.

  16. Erika: evaluation of residual sanitary risks linked to the beaches-going after cleaning-up; Erika: evaluation des risques sanitaires residuels lies a la frequentation des plages apres depollution

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The aim of this study is to evaluate the sanitary risks for the populations frequenting the coast beaches affected by the fuel oils of the tanker Erika, after their cleaning up. This quantitative evaluation of sanitary risks is led according to a protocol developed jointly between the two institutes ( the national institute of industrial environment and risks, I.N.E.R.I.S., and the national institute of sanitary watch I.n.V.S.). It does not give the risks in function the residual pollution level of concerned beaches but supplies to the authorities elements of scientific information in order to allow them to choose criteria appropriate for the management of eventual residual risks. (N.C.)

  17. Los sistemas estandarizados de evaluación en Chile: participación de Mario Leyton Soto y Erika Himmel König

    OpenAIRE

    Caiceo Escudero, Jaime

    2015-01-01

    Educational evaluation, as the science of education, began to be developed and applied in Chile only starting from the sixties of the last century. Indeed, several Chilean educators were to his PhD to United States of America in these areas; among them are Mario Leyton and Erika Himmel, who specialized in curriculum and evaluation, through the approaches of Tyler and Bloom. Therefore, both were actively involved in the introduction into the country of two measurement systems: (1) selection fo...

  18. Evaluation of the residual sanitary risk for people spending time on the beaches polluted by the Erika fuel, after the depollution

    International Nuclear Information System (INIS)

    Dor, F.; Gourier-Frery, C.; Zmirou, D.; Cicolella, A.; Bonnard, R.; Dujardin, R.

    2004-01-01

    This study aims to evaluate the short dated and long dated sanitary risks for adults and children who are going to spend time on the beach affected by the Erika fuel, after the depollution. 36 beaches were selected and 7 beaches which were not polluted, were taking as a reference. The methodology, the analysis of the data and the results are described. (A.L.B.)

  19. Evaluation of the residual sanitary risk for people spending time on the beaches polluted by the Erika fuel, after the depollution; Evaluation du risque sanitaire residuel pour les populations frequentant les plages polluees par le fioul rejete par l'ERIKA, apres depollution

    Energy Technology Data Exchange (ETDEWEB)

    Dor, F.; Gourier-Frery, C.; Zmirou, D. [Institut de veille sanitaire, 94 - Saint-Maurice (France); Cicolella, A.; Bonnard, R.; Dujardin, R. [Institut National de l' Environnement Industriel et des Risques, 60 - Verneuil en Halatte (INERIS) (France)

    2004-07-01

    This study aims to evaluate the short dated and long dated sanitary risks for adults and children who are going to spend time on the beach affected by the Erika fuel, after the depollution. 36 beaches were selected and 7 beaches which were not polluted, were taking as a reference. The methodology, the analysis of the data and the results are described. (A.L.B.)

  20. Imágenes en duelo : Víctimas del conflicto armado colombiano en la cámara de Erika Diettes

    OpenAIRE

    Cardona González, Lorena

    2015-01-01

    La propuesta de este texto es la de hacer un perfil artístico de la fotógrafa colombiana Erika Diettes. Su trabajo ha estado enmarcado en los últimos años por el encuentro testimonial y fotográfico con las víctimas del conflicto armado colombiano, en éste se destaca un profundo ejercicio de memoria visual en el que las víctimas han aportado, no solo su rostro o los objetos de familiares desaparecidos, sino su palabra y su memoria traumática. Este trabajo, traducido en exposiciones, obras e in...

  1. Sanitary impact of cleaning operations following the pollution bred by the Erika wreck: evaluation and prevention. Synthesis of available data and recommendations; Impact sanitaire des operations de nettoyage consecutives a la pollution engendree par le naufrage de l'Erika: evaluation et prevention. Synthese des donnees disponibles et recommandations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-04-01

    The I.N.E.R.I.S. (Institut National de l'Environnement Industriel et des Risques) report relative to the consequences of cleaning operations following the pollution bred by the Erika wreck gives the following conclusions: whatever the pollutants are, the carcinogen risks by pulmonary way are negligible for people assigned to the beaches cleaning; the general carcinogen effects, linked to benzopyrene in organism after skin crossing, have been evaluated as negligible; there is a non negligible risk for the embryo-fetal development linked to the benzopyrene skin crossing; It is not possible to tell if the skin cancer risk is or not negligible, because of the uncertainty of the dose effectively absorbed by the skin and the lack of acceptable toxicological references; the risks linked to the volatile organic compounds are negligible; an uncertainty exists on the risks linked to the thiophene family that have not been determined, because of the deficiency of base data. For the second study, whatever the studied scenario, the R.I.V.M. (Riijksinstituut Voor Volksgezondheid en mileuhygiene) Dutch organism report concludes to a risk qualified as acceptable for the voluntary workers and professionals, included the birds cleaners. The risk of skin cancer consecutive to the skin exposure has been characterized with a dose response relationship model coming from previous works of the R.I.V.M. (N.C.)

  2. Tahaks eestlaseks saada / Erika Klaats

    Index Scriptorium Estoniae

    Klaats, Erika, 1954-

    2000-01-01

    Vt. ka Molodjozh Estonii : Subbota Sep/2 lk. 10. Venelased panevad lapse eesti kooli, kuid ei arvesta sellega, et võõras keeles õppides ei pruugi laps koolis edukalt edasi jõuda. Lisa: Eesti koolid, kus saab õppida vene keeles

  3. Suzuki ja Szilvay : meetodist ja individuaalsusest / Lembi Mets

    Index Scriptorium Estoniae

    Mets, Lembi

    2000-01-01

    23. ja 24. apr. esines Tallinnas ans. Helsingin Juniorijousten F-avain-sello-bassoryhmä. 3. mail esines Tallinnas keelpilliõpilaste orkester Suzuki Nordic String. Suzuki ja Szilvayde muusikaõpetuse meetoditest, nende erinevustest, kasutamisvõimalustest Eestis

  4. Mõnedest mesoliitilistest faunakompleksidest Läänmere idakaldal / Lembi Lõugas

    Index Scriptorium Estoniae

    Lõugas, Lembi, 1967-

    2008-01-01

    Loomaluude kompleksne uurimine selgitab antud paigas elanud inimeste majanduslikud suundumused. Artiklis on analüüsitud Pärnu ümbrusest, Lääne-Eestist ja Lääne-Lätist pärit loomaluudekogumeid

  5. Growth and condition of juvenile sole (Solea solea L. as indicators of habitat quality in coastal and estuarine nurseries in the Bay of Biscay with a focus on sites exposed to Erika oil spill

    Directory of Open Access Journals (Sweden)

    Camille Gilliers

    2006-06-01

    Full Text Available Indicators of growth and condition were used to compare the habitat quality of nurseries of juvenile sole (Solea solea L. in the Bay of Biscay, based on one survey in 2000. The four biological indicators are poorly correlated with each other, suggesting that no single measure may give an adequate description of fish health and of its habitat’s quality. Growth indicators showed significant differences between northern and southern areas. Juveniles from the two southernmost nurseries, the Gironde estuary and the Pertuis Antioche, displayed significant lower otolith increment widths and mean sizes. These differences were inversely related to water temperature and unrelated to genetic or age differences, and are unlikely to be due to limiting trophic conditions in the nurseries. Hence, they may be considered in terms of differences in habitat quality and potential anthropogenic impacts. Condition indices do not show this north-south pattern but highlight low condition values in the Pertuis Antioche. Short-term and fluctuating biochemical indicators such as RNA/DNA ratios appeared to be unreliable over a long-term study, while morphometric indices seemed to be relevant, complementary indicators as they integrate the whole juvenile life-history of sole in the nurseries. The growth and condition indices of juveniles in September 2000 from nursery grounds exposed to the Erika oil spill in December 1999 were relatively high. These results lead us to suggest that there was no obvious impact of this event on the health of juvenile sole and on the quality of the exposed nursery grounds a few months after the event.

  6. Kunstnik kavatseb maalidest jaanitule teha / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2005-01-01

    Andrus Older teeb jaanitule oma piltidest, mis jäävad ostmata oksjonil, mille ta korraldab päev enne Sillamäe lähedal Orava talus. Harrastuskunstnik paneb müüki umbes 50 maali. Kunstniku kommentaarid

  7. Tuuma ümberprogrammeerimine / Erika Jonietz

    Index Scriptorium Estoniae

    Jonietz, Erika

    2006-01-01

    Lootuses lahendada embrüotüvirakkude ümber käiv vaidlus, pakub Oregoni meditsiiniülikooli juures asuva tüvirakukeskuse juhataja Marcus Crompe eetilisemat võimalust rakkude tootmiseks. Artikkel üldpealkirja all: 10 tulevikutehnoloogiat

  8. «  Erika hätte so gern ein Bild von Koch ». Materielle Erinnerungskulturen in Mädchenschulen in Österreich und Deutschland in der ersten Hälfte des 20. Jahrhunderts

    Directory of Open Access Journals (Sweden)

    Li Gerhalter

    2011-11-01

    Full Text Available « Erika aimerait tellement avoir une image de la Koch ». Cultures matérielles de la mémoire dans des écoles pour jeunes filles en Autriche et en Allemagne pendant la première moitié du XXe siècle.Le présent article se situe à la croisée de problématiques formulées, d’une part, par l’histoire du genre et les études sur l’auto/biographie et les ego-documents, et d’autre part, par l’histoire de l’amitié et du patronage, l’histoire des émotions ainsi que les recherches sur la culture matérielle. En effet, l’étude d’un ensemble de journaux intimes et de correspondances, tenus par des jeunes filles issues de milieux bourgeois en Autriche et en Allemagne pendant la première moitié du XXe siècle, permet de dégager trois séries d’objets qui circulent entre les élèves mais aussi entre élèves et enseignantes et qui, en matérialisant ainsi les relations affectives (d’amitié, d’admiration, etc. en milieu scolaire, deviennent des objets mémoriels. Ce sont avant tout les cahiers de souvenirs, des lettres ainsi que des portraits photographiques qui s’échangeaient suivant des logiques spécifiques, dont l’article se propose de relever les contraintes, les possibilités et les temporalités propres au parcours scolaire. Les classes, exclusivement féminines, sont considérées comme des ensembles sociaux fortement hiérarchisés mais au sein desquels relations formelles et informelles entre les élèves et les enseignantes s’imbriquaient étroitement. Les objets échangés entre élèves et ceux échangés entre élèves et enseignantes étaient les mêmes ; les modalités des échanges en revanche étaient clairement plus hiérarchiques dans le second cas. Si la nature des faveurs (une lettre, une photo ou un mot écrit sur le cahiers de souvenirs que demandaient les élèves à une camarade ou à une enseignante, était la même, l’enseignante n’y accédait que rarement ; les enseignantes ne

  9. Munitsipaalmaja : Tallinn, Erika t. 9 = Municipal Housing : Tallinn, Erika St. 9 / Liina Jänes

    Index Scriptorium Estoniae

    Jänes, Liina, 1977-

    2003-01-01

    120 korteriga munitsipaalelamu on 1953. a. pärineva stalinistliku lagunenud kasarmuhoone rekonstruktsioon. Projekteerija: Rein Murula Arhitektuuribüroo. Autorid: Rein Murula, Marti Kahu, Karl Koosa. Konstruktor Tõnu Rausberg (TA-Konsult). Projekt ja hoone valmis: 2002. I, IV ja katusekorruse plaan, 4 välisvaadet

  10. A dual shared stack for FSLM in Erika Enterprise

    NARCIS (Netherlands)

    Balasubramanian, S.M.N.; Afshar, S.; Gai, P.; Behnam, M.; Bril, R.J.

    2017-01-01

    Recently, the flexible spin-lock model (FSLM) has been introduced, unifying spin-based and suspension-based resource sharing protocols for real-time multi-core platforms. Unlike the multiprocessor stack resource policy (MSRP), FSLM doesn’t allow tasks on a core to share a single stack, however. In

  11. Medieval and Early Modern Suburban Site in Tallinn, Tartu mnt Road 1: Artefacts and Ecofacts / Erki Russow, Lembi Lõugas, Liina Maldre ... [jt.

    Index Scriptorium Estoniae

    2013-01-01

    Kivisilla eeslinna kaevamistelt saadud materjal on erakordselt rikkalik ja artiklit võib lugeda põgusaks katseks esitada ülevaade leitud keraamikast, nahaleidudest, metall-leidudest, klaasikollektsioonist, luuesemetest, loomaluudest, kalaluudest, taimejäänustest ja õietolmust

  12. 20 aastat tagasi talletatud Siberi elulugudest valmib telesari / Gerda Kulli-Kordemets ; intervjueerinud Erika Klaats

    Index Scriptorium Estoniae

    Kulli-Kordemets, Gerda

    2010-01-01

    Uuest telesarjast tööpealkirjaga "Siber", mis räägib 14. 06. 1941 Virumaalt küüditatud politseinike lastest, kes viidi Tomski oblastisse Vasjuganje piirkonda. Stsenarist Merle Karusoo, kunstnik Eugen Tamberg, tegevprodutsent Mart Saar. Dokumentaalfilm tööpealkirjaga "Memento" tutvustab telesarja tegelaste prototüüpe ja reaalseid tegevuskohti. ETV võttegrupi käigust Tomski oblastisse

  13. Tööõnnetuste arv Ida-Virus väheneb / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2004-01-01

    Ilmunud ka: Severnoje Poberezhje, 7. dets. 2004, lk. 3. Tööinspektsiooni viimase üheksa aasta statistikast järeldub, et tööõnnetuste arv on Ida-Virumaal aastatega vähenenud peaaegu poole võrra

  14. HIV-positiivse ema laps ei pruugi nakkust saada / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2004-01-01

    Vt. ka Severnoje Poberezhje 29. okt., lk. 3. Ida-Virumaal emalt lapsele HI-viiruse leviku ennetamise projekti juhi Tiia Perteli sõnul on lapse nakatumine vaid 2-3%, kui HIV-positiivne rase end varakult arsti juures arvele võtab ja rakendusele võetakse kõik tervishoius olemas olevad ennetusmeetodid

  15. HIV-positiivsete ja narkomaanide kohta tahetakse luua andmebaas / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2004-01-01

    Vt. ka Severnoje Poberezhje 18. veebr., lk. 3. Projekti "HIV-positiivsete avastamine Jõhvis" raames sai Jõhvi noorteabikeskus läinud aasta detsembris informatsiooni 50 HIV-positiivse kohta, neist viis on väikese lapsega haiglas olnud emad

  16. Predicting work-related flow in the chemical industry / Erika Maree

    OpenAIRE

    Maree, Erika

    2008-01-01

    In a new world of work characterised by competitiveness, benchmarking, technological innovation and efficiency, the South African chemical industry needs to function at an optimal level to meet the demands of its stakeholders and employees. The industry needs leadership of the highest standard and an efficient, productive workforce. The objective of this study was to determine the relationship between leader empowering behaviour, self-efficacy, job resources and work-related flow for empl...

  17. Pikiuuring õpetajaks õppijate professionaalse identiteedi kujunemisest / Katrin Poom-Valickis, Erika Löfström

    Index Scriptorium Estoniae

    Poom-Valickis, Katrin, 1969-

    2014-01-01

    Uurimusest, mille eesmärgiks oli analüüsida õpetajakoolituse üliõpilaste õpetajaidentiteedi aluseks olevaid tähendusi ja uskumusi, mis on loodud interaktsioonis keskkonnaga, sh ülikooli õpingute käigus kogetuga

  18. Kiviõli vene gümnaasiumi seinu ehivad fresko ja mosaiik / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2002-01-01

    Rahvusvaheline kunstiinimeste seltskond maalib kooli seinale looduslike värvidega fragmente Kiviõli linna ajaloost ning paneb kokku kahhelkivitükikestest mosaiigi. Üritus kannab nime Fresko festival. Kunstiline juht on sakslane Martin Kramer

  19. Stenõ Kiviõliskoi russkoi gimnazii ukrasjat freski i mozaika / Erika Prave

    Index Scriptorium Estoniae

    Prave, Erika, 1970-

    2002-01-01

    Rahvusvaheline kunstiinimeste seltskond maalib kooli seinale looduslike värvidega fragmente Kiviõli linna ajaloost ning paneb kokku kahhelkivitükikestest mosaiigi. Üritus kannab nime Fresko festival. Kunstiline juht on sakslane Martin Kramer

  20. Telesügis: uued omasaated ja õnnemängud / Erika Klaats

    Index Scriptorium Estoniae

    Klaats, Erika, 1954-

    2010-01-01

    ETV ekraanile jõudvatest draamasarjadest "Klass: elu pärast" ja "ENSV" ning Mati Talviku ajaloosarjast "Ajavaod". Kanal 2 ekraanile jõudvast draamasarjast "Pilvede all", dokumentaalsarjast "Eesti maffia", saatest "Tantsud tähtedega". TV 3 ekraanile jõudvast saatest "Eesti talent" ja komöödiasarjast "Kälimehed" (stsenarist Peep Pedmanson)

  1. Evaluation of the sanitary and environmental risks resulting from the Erika sinking and from the coasts cleaning operations; Evaluation des risques sanitaires et environnementaux resultant du naufrage de l'ERIKA et des operations de nettoyage des cotes

    Energy Technology Data Exchange (ETDEWEB)

    Cicolella, A

    2000-03-15

    This synthesis presents the methodology of the risks evaluation and of the INERIS report, the products analysis, general data on polycyclic aromatic hydrocarbons, the exposure evaluation, the sanitary impact evaluation for the polycyclic organic hydrocarbons and volatile organic compounds and the evaluation of ecological risks. (A.L.B.)

  2. An implementation of the flexible spin-lock model in ERIKA Enterprise on a multi-core platform

    NARCIS (Netherlands)

    Afshar, S.; Verwielen, M.P.W.; Gai, P.; Behnam, M.; Bril, R.J.

    2016-01-01

    Recently, the flexible spin-lock model (FSLM) has been introduced, unifying spin-based and suspension-based resource sharing protocols for real-time multiprocessor platforms by explicitly identifying the spin-lock priority as a parameter. Earlier work focused on the definition of a protocol for FSLM

  3. Book review. Manuale delle attività investigative per i reati contro la fauna. Rosario Fico, Simone Angelucci, Erika Ciarrocca

    Directory of Open Access Journals (Sweden)

    Manuel Graziani

    2014-06-01

    Full Text Available Il manuale realizzato dal Parco Nazionale della Majella, IZS di Lazio e Toscana, Corpo Forestale dello Stato e Legambiente, è il primo tentativo di tracciare un percorso condiviso nell'ambito delle investigazioni per i reati contro gli animali. Le attività di bracconaggio o di uccisione illegale di animali, infatti, rappresentano ancora oggi un fenomeno tristemente attuale nel nostro Paese; si pensi ai tanti lupi uccisi per avvelenamento o attraverso lacci e armi da fuoco. Gli autori del manuale, realizzato con il cofinanziamento della CE nell'ambito del progetto Life Wolfnet "Development of coordinated protection measures for Wolf in Apennines", sono medici veterinari che ben conoscono la materia, a partire dal dott. Rosario Fico che dirige il Centro di Referenza Nazionale per la Medicina Forense Veterinaria dell'IZS di Lazio e Toscana. La pubblicazione nasce da un progetto, teso alla conservazione e gestione coordinata del Lupo nell'Appennino, che in primis ha messo in atto azioni dirette a ridurre il conflitto verso il lupo conseguente a sistemi normativi e procedurali di indennizzo del danno insufficienti, per poi combattere l'ostilità nei suoi confronti da parte degli allevatori e delle comunità locali. Sono state inoltre intraprese azioni per contrastare il fenomeno della mortalità illegale, ridurre la persistenza di rischi o lo sviluppo di nuove criticità sanitarie per la popolazione di lupo. Il progetto ha infine avviato attività finalizzate alla riduzione del disturbo diretto o indiretto al lupo e l'attivazione di un Network istituzionale. Il manuale è strutturato in 8 capitoli: Normativa essenziale; Ruoli e competenze; La scena del crimine; Dopo la scena del crimine; Il video-foto-trappolaggio come strumento di prevenzione e di indagine; Casi studio; Procedura operativa per la necroscopia del lupo; Modulistica. Da segnalare i contributi di Rita Lorenzini e Antonio Antonucci che si aggiungono ai tre autori principali.

  4. Evaluation of the sanitary and environmental risks resulting from the Erika sinking and from the coasts cleaning operations

    International Nuclear Information System (INIS)

    Cicolella, A.

    2000-03-01

    This synthesis presents the methodology of the risks evaluation and of the INERIS report, the products analysis, general data on polycyclic aromatic hydrocarbons, the exposure evaluation, the sanitary impact evaluation for the polycyclic organic hydrocarbons and volatile organic compounds and the evaluation of ecological risks. (A.L.B.)

  5. Selgusid kirjanduse aastapreemiate saajad / Rein Veidemann ; komment. Karl Martin Sinijärv, Viivi Luik

    Index Scriptorium Estoniae

    Veidemann, Rein, 1946-

    2006-01-01

    Eesti Kultuurkapitali aastapreemiad: Kristiina Ehini luulekogu "Kaitseala" ja Jürgen Rooste luulekogu "Ilusaks inimeseks", Piret Raud "Sanna ja salakütid", Merle Karusoo näidend "Misjonärid", Madis Kõivu artiklikogumik "Luhta-minek". Tõlkepreemiad tõlkijatele Anu Saluäär, Heili Einasto, Lembi Loigu, Veronika Kivisilla, Risto Järv. Vabaauhind Käbi Laretei. Artiklipreemia Aare Pilv. Venekeelse autori kirjandusauhind Gohar Markosjan-Käsper, Svetlan Semenenko

  6. Trends and priorities in the development of the Latvian banking services in the context of emerging knowledge based economy : case of e-banking / Valters Kazhe, Ilona Baumane, Erika Shumilo...[jt.

    Index Scriptorium Estoniae

    2007-01-01

    Läti pangateenuste arengutrendidest ja -prioriteetidest teadmistepõhise majanduse kontekstis. Probleemidest Läti finantssektori arengus, e-panganduse teenustest ning nende laiendamise perspektiividest. Joonised

  7. 75 FR 12199 - Stainless Steel Bar from India: Preliminary Results of Antidumping Duty Administrative Review

    Science.gov (United States)

    2010-03-15

    ... administrative review. See Memorandum from Erika McDonald to the File, ``Relationship of Venus Wire Industries... the 2008-2009 administrative review. See Memorandum from Erika McDonald to the File, ``Relationship of... otherwise adds value to the merchandise; (6) the means of marketing a product by the producer to the U.S...

  8. Uued raamatud

    Index Scriptorium Estoniae

    2007-01-01

    Calin Dani raamatust "Emotional architecture 2" (Hand Milked Visions Faundation, 2006), mis on mõeldud saatjaks C. Dani filmile "Trip" (2005) Raine Karbi Tallinna Linnahallist. Erika Nõva raamatust "Erika Nõva : minu töö ja elu" (Tallinn : Eesti Arhitektuurimuuseum, 2006), mille on koostanud Anne Lass, kujundanud Irina Tammis

  9. 21. X avati Kaunase kunstibiennaal "Textile 2005"

    Index Scriptorium Estoniae

    2005-01-01

    Eestist osalevad Mare Kelpmann, Marika Kööbi, Aet Ollisaar, Kadi Pajupuu, Ludmilla Svarzhevska, Hanna Tiidus, Helen Kauksi, Krista Leesi, Aune Taamal, Erika Tammpere, Milvi Thalheim ja Erle Võsa-Tangsoo

  10. Sowjetunion und Völkerrecht 1962-1973 / Henn-Jüri Uibopuu

    Index Scriptorium Estoniae

    Uibopuu, Henn-Jüri, 1929-2012

    1980-01-01

    Tutvustus: Sowjetunion und Völkerrecht 1962-1973 : Bibliographie und analyse / hrsg. Boris Meissner, Dietrich Frenzke und Erika Chilicki. Köln : Wissenschaft und Politik, 1979 [t.p. incorrectly: 1977

  11. Näitused / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    1998-01-01

    Vaal-galerii: Peeter Laurits "Taeva Atlas" (gigitaaltehnoloogias kollaazhid); Sammas-galerii: "Maailma nägu"; Tartu Kunstimaja: "Viljandi kunstipäevad Tartus"; Estonia Talveaed: Mall Mets&Erika Pedak "Due Canzoni" (vaibakunst).

  12. 77 FR 5308 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-02-02

    ... ALBERT MAYER CONNOLLY WINSTON COOKSON GORDON POWER COONEY JOHN CUBAUD NICOLAS EDGARD CUDDY DAVID R... TAKEUCHI ERIKA TAN AH-SWAT TAN YEW KHUAN TANG MISI TANNER DAVID A TANNER JACQUELINE........ A TAUSCH HENRI...

  13. Lower Your Stroke Risk (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Stroke is among the leading causes of death and disability worldwide. In the U.S., strokes are more common among women. In this podcast, Dr. Erika Odom discusses ways to decrease your chances of having a stroke.

  14. Kes on šõuilma tuntuimad (pool)eestlased? / Priit Pullerits

    Index Scriptorium Estoniae

    Pullerits, Priit, 1965-

    2009-01-01

    Eesti päritolu maailmas tuntud meelelahutusmaailmas osalejatest (Mena Suvari, Ornella Muti, Miliza Korjus, Kalev Mark Kostabi, Edmund Valtman, Erika Eleniak, Alar Kivilo, Ants Robert Kristian Luuk, Sonny Arahanga jt)

  15. Selecting of a cytochrome P450cam SeSaM library with 3-chloroindole and endosulfan – Identification of mutants that dehalogenate 3-chloroindole

    DEFF Research Database (Denmark)

    Kammoonah, Shaima; Prasad, Brinda; Balaraman, Priyadarshini

    2018-01-01

    ; the wild-type did not accommodate 3-chloroindole in the active site, whereas all the mutants did. We propose two potential reaction pathways for dechlorination of 3-chloroindole. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner...

  16. Keelesümpoosion arutas Põhjamaade mõistet / Ülo Ignats ; fotod: Ülo Ignats

    Index Scriptorium Estoniae

    Ignats, Ülo, 1951-2011

    2006-01-01

    Stockholmis Riigipäeva teise koja saalis teemal "Kuivõrd põhjamaine on Baltikum". Ettekannetega esinesid: Kristel Zilmer, Battail, Jean-Francois Battail, Torkel Jansson, Madis Kanarbik, Stig Örjan Ohlsson, Ivars Orehovs, Erika Sausverde, Thomas Lundén, Katrin Maandi, Kristel Kääramees

  17. 77 FR 33000 - Solicitation for a Cooperative Agreement: Resources for NIC's Web Site on Data Collection and...

    Science.gov (United States)

    2012-06-04

    ..., development of statistical and assessment applications using standard html and java script, asp.net and Excel... the application procedures should be directed to Erika McDuffe, Program Specialist, NIC Jails Division... stay, average daily population); staffing levels, and; corrections activities and programs. It is not...

  18. Juicebox Gallery

    International Development Research Centre (IDRC) Digital Library (Canada)

    2012 and 2014 IDRC Research Awardee Ahmed K. Rashid Erika Malich, Piura University, Piura, Peru Ääremaal võib kohata ilusaid maalähedasi hooneid / Tõnu Kann

    Index Scriptorium Estoniae

    Kann, Tõnu, 1957-

    2009-01-01

    Tõnu Kanni ja Henn Soodla matk Pärnumaa 20. sajandi väärtarhitektuuri jälgedes, kaasas kunstiteadlase Epp Lankotsi koostatud Eesti 20. sajandi arhitektuuri kaitseprogrammi nimestik kaitsealustest objektidest Urissaares, Massiarus, Metsapooles ja Võidukülas, viimases uudismaa-asunduste hooned projekteeris Erika Nõva, Massiaru koolimaja autor oli Märt Merivälja

  19. Travel to Learn: How, When, and Why to Apply for Overseas Professional Development

    Science.gov (United States)

    Cook, Erika; Becker, Aaron

    2013-01-01

    In this article, Erika Cook and Aaron Becker suggest teachers travel to "unfamiliar" lands to not only breathe life into global lessons but also to gain new perspectives and experiences as educators. For teachers who dread teaching about an unfamiliar place or culture, Cook and Becker recommend considering the very real opportunities to…

  1. Lower Your Stroke Risk (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2015-11-05

    Stroke is among the leading causes of death and disability worldwide. In the U.S., strokes are more common among women. In this podcast, Dr. Erika Odom discusses ways to decrease your chances of having a stroke.  Created: 11/5/2015 by MMWR.   Date Released: 11/5/2015.

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    pp 157-166 Articles. Ammonia differentially suppresses the cAMP chemotaxis of anterior-like cells and prestalk cells in Dictyostelium discoideum · Ira N Feit Erika J Medynski Michael J Rothrock · More Details Abstract Fulltext PDF. A drop assay for chemotaxis to cAMP confirms that both anterior-like cells (ALC) and prestalk ...

  3. Bagatellid : maailm / Mailis Põld

    Index Scriptorium Estoniae

    Põld, Mailis

    2006-01-01

    Muusikasõnumeid mujalt maailmast: Matusemuusikust ooperidiiva Erika Sunnegardh. Lionel Bringuier - noor talent dirigentide seas. Riccardo Muti naudib vabakutselise staatust. Mstislav Rostropovitsh lõpetab sooloesinemised. Lahkumisest on teatanud maestro Wolfgang Sawallisch. Arturo Benedetti Michelangeli preemia läheb sel aastal rumeenlasele pianist Radu Lupule.

  4. Miks olen Reformierakonnas?

    Index Scriptorium Estoniae

    2005-01-01

    Küsimusele vastavad reformierakondlased Reno Laidre, Viivi Maremäe, Ott Kasuri, Kristjan Kahm, Erika Vahtramäe, Urmas Suik, Priit Laineste, Silver Meikar, Kattri Ezzoubi, Anton Teras ja riigikogu liikmed Kristiina Ojuland, Igor Gräzin, Tõnis Kõiv ning Helmer Jõgi

  5. Making the case for open access to research | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Research should be a public good,” says 2016 IDRC Research Award recipient Erika Malich. “No matter how rigorous it ... “We need to think about how the research is communicated to various audiences, and ways of involving beneficiaries throughout the process to increase understanding and use.” Through this research ...

  6. Uued näitused Pärnus Chaplini keskuses

    Index Scriptorium Estoniae

    1998-01-01

    11. jaan. - 26. veebr. Erika Pedaku isiknäitus "Protsess", eksponeeritud Kyoto V rahvusvahelisel tekstiilivõistlusel Excellence Awardiga pärjatud vaip "Roheline" ja viis uuemat tööd ning ajalooline läbilõige eesti vaibakunsti arengust "Soojad mustrid", mille dominant on 1915. a. Oskar Kallise kavandi järgi kootud vaip "Ussikuningas".

  7. Characterization and behavior in the environment of the crude oil ''Prestige''; Caracterisation et comportement dans l'environnement du fioul ''Prestige''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-03-01

    This study presents analysis realized on the crude oil of the tanker ''Prestige'' which sunk the 19 november 2002. The specifications on the product and its behavior in sea water are detailed. All the analysis are compared to the ''Erika'' crude oil. (A.L.B.)

  8. Easy on the Salt (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Heart disease and stroke are among the leading causes of death in the U.S., and they have one major risk behavior in common: excessive consumption of sodium. In this podcast, Dr. Erika Odom discusses the importance of a low-sodium diet.

  9. Munitsipaalehitus jätkub uue hooga

    Index Scriptorium Estoniae

    2007-01-01

    Tallinna linnavalitsus kiitis heaks 1170 munitsipaalkorteri rajamise. Ehitab OÜ Raadiku Arendus. AS-ilt Facio Ehitus on Tallinna linn tellinnud Koplisse Erika t. 13a 136 korteriga munitsipaalelamu, mille 10 korterit on mõeldud liikumispuudega inimestele. Viimase seitsme aastaga on Tallinna kerkinud 23 munitsipaalelamut

  10. Easy on the Salt (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2015-07-02

    Heart disease and stroke are among the leading causes of death in the U.S., and they have one major risk behavior in common: excessive consumption of sodium. In this podcast, Dr. Erika Odom discusses the importance of a low-sodium diet.  Created: 7/2/2015 by MMWR.   Date Released: 7/2/2015.

  11. ["Lääne Elu" väljakuulutatud jõululuuletuste konkursil osalejad

    Index Scriptorium Estoniae

    2003-01-01

    Taive Kesseli "Toa nurgas jõulupuu ehete säras..." ; Ülle Ehala "Advent" ; Heldi Leidsalu "Laul jõuluvanale" ; Silja Paulus "Olen olnud paha laps" ; Erika Raudsepp "Jõuluvanal "Kopp on ees"..." ; Kelvin Vaske "Jõulususs ootab" ; Allar Lillenurm "Öö sinine, helge..." ; Maarja-Liis Mäeste "Jõululuuletus" ; Merilin Serg "Lumi tuli" ; Silvi-Astrid Mickelin "Sajandite reel", "Hing ihkab"

  12. Annual Report 2000; Rapport annuel 2000

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    This annual report gives the activities during the year 2000 and information about the General Direction of the Energy and Raw Materials (DGEMP) in France. The highlights of the year are discussed in the main following topics: public utilities, the Erika oil slick, the petroleum products prices increase, the energy efficiency national program, Eole 2005, the nuclear industry management. The french energy accounting, the publications and the organization of the DGEMP are also provided. (A.L.B.)

  13. Annual Report 2000

    International Nuclear Information System (INIS)

    2000-01-01

    This annual report gives the activities during the year 2000 and information about the General Direction of the Energy and Raw Materials (DGEMP) in France. The highlights of the year are discussed in the main following topics: public utilities, the Erika oil slick, the petroleum products prices increase, the energy efficiency national program, Eole 2005, the nuclear industry management. The french energy accounting, the publications and the organization of the DGEMP are also provided. (A.L.B.)

  14. Sphygmo 2014 (Sphygmo is...)

    OpenAIRE

    Callus, Leonard; Mifsud, Melise

    2014-01-01

    Contents: Spooky Hospitals - Melise Mifsud; Doctors of Horror - Julia Shaaban; Weird & Scary Medical Inventions - Stephanie Farrugia; Experience in Voluntary Work - Kyle Cilia; Voluntary Work & Its surprising Benefits - Georgina Farrugia; Strange & Unusual Remedies - Stephanie Farrugia and Stephanie Pullicino; Doctors of the Past - Erika Babatunde; Mythical or Human? - Sahra A. Haji; Doctors Gone Bad - Maria Grazia Grech; Medical Discoveries by Chance - Vanessa Mercieca; Diet Myths & Tips - R...

  15. Strategy of Slovak Republic's government to use higher education as an investment into human capital

    OpenAIRE

    Smereková, Erika

    2016-01-01

    Bc. Erika Smereková Strategy of Slovak Republic's Government to use higher education as an investment in human capital Abstract The Master thesis on the topic "Strategy of Slovak Republic's government to use higher education as an investment in human capital" presents results to the following research question: To what extent is it a part of strategy of Slovak Republic's educational policy to use higher education as an investment in human capital? The thesis specifically focuses on the idea o...

  16. Report made on behalf of the inquiry commission for the enforcement of the measures preconized for the safety of the maritime transport of hazardous or polluting products and for the evaluation of their efficiency; Rapport fait au nom de la commission d'enquete sur l'application des mesures preconisees en matiere de securite du transport maritime des produits dangereux ou polluants et l'evaluation de leur efficacite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    On February 5, 2003, three years after the creation of an inquiry commission about the Erika tanker-ship wreck, the principle of a new inquiry commission about the safety of maritime transports was decided by the French house of commons. Its mission is: to evaluate the efficiency of the existing measures of prevention of marine pollution by hydrocarbons, to examine if the preconized safety measures for the transport of dangerous or polluting products are effectively enforced, and to evaluate the status of the transposition of the European directives relative to the control of hazardous ships. This document is the first tome of the report made on behalf of this inquiry commission. It comprises four parts dealing with: 1 - the Prestige tanker-ship wreck and the pollution of Spanish and French coasts: similarities with the Erika wreck but differences in the conditions of crisis management, diverging accident analyses, problems encountered in Spain, a significantly improved management of the crisis by the French administration, the public opinion and the local economy, the global increase of maritime transport and the reduction of accidents frequency; 2 - the real improvements after the Erika wreck: the significant advances but their partial implementation, the acceleration of actions following the Prestige wreck; 3 - the expected and realistic perspectives: the sustain of the political will at the national scale, the concretizing of the European decisions and the follow up of the retained trends, the need for more outstanding evolutions at the international scale; 4 - the international liability and compensation regime: its limitation to the hydrocarbons pollution, the lack of victims indemnification in the case of chemical pollution, the need for an increase of the liability of all actors of the maritime transport and the improvement of the compensation system, a community compensation fund to compensate the inefficiencies of the international compensation mechanisms

  17. Pediatric Susceptibility to Nerve Agent-Induced Seizures and Effectiveness of Anticonvulsant Treatments

    Science.gov (United States)

    2014-12-01

    NUMBER 5e. TASK NUMBER E-Mail: ed.dudek@hsc.utah.edu, Erika.scholl@hsc.utah.edu, 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME...Straub tail. Piloerection, hyper- lacrimation and exopthalmos were observed in P21 and P28 rats. Vocalizations were audible at P7 and P14. Due to the...effects of DFP as a function of age As illustrated in Table 1, behavioral seizures in P28 rats, defined generally as whole body tremors, were observed at

  18. Kas Eesti avastamine algab Põhja-Eestist? : Põhja-Eesti V turismikonverents

    Index Scriptorium Estoniae

    2010-01-01

    17. novembril Jõhvi Kontserdimajas toimunud Põhja-Eesti V turismikonverentsist “Kas Eesti avastamine algab Põhja- Eestist?", mille avas Ida-Virumaa maavalitsuse Arengu- ja planeeringuosakonna juhataja Urmas Majaääs. Ülevaade SA Ida-Virumaa Ettevõtluskeskuse turismikoordinaatori Sigrid Karoni, Estonian Airi asepresidendi kommertsalal Rauno Parrase, EASi koordinaatori turismiuuringute alal Piret Kallase, kommunikatsioonikonsultandi Raul Rebase, SA Põhja-Eesti Turism projektijuhi Erika Pääbuse ja nõukogu liikme Moonika Sooneste, CityBike OÜ tegevjuhi Toomas Lelovi, Narva-Jõesuu linnapea Andres Noormägi, Loodusturismi arendaja ja koolitaja Rein Kuresoo ettekannetest

  19. Rapid Translation of a Novel and Potent Vaccine in HER2+ Metastatic Breast Cancer Patients

    Science.gov (United States)

    2013-10-01

    Xia3, Neil Spector2,3, Larry S Barak4, Timothy M Clay5, Takuya Osada2, Erika Hamilton6, Kimberly Blackwell6, Amy C Hobeika2, Michael A Morse2,3, H Kim...Zhang L, Boehm MF, Fritz LC, Burrows FJ: A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors. Nature 2003, 425:407...410. 13. Zhang H, Burrows F: Targeting multiple signal transduction pathways through inhibition of Hsp90. J Mol Med (Berl) 2004, 82:488-499. 14. Basso

  20. Současné postupy v diagnostice, léčbě a prevenci infekce vyvolané methicilin rezistentními kmeny bakterie Staphylococcus aureus (MRSA)

    OpenAIRE

    Korejsová, Erika

    2013-01-01

    Candidate: Erika Korejsová Supervisor: Mgr. Klára Konečná, Ph.D. Consultant: MUDr. Marie Smolíková Title: Current methods in diagnostics, treatment and prevention of infection caused by methicilin resistant Staphylococcus aureus (MRSA) Bachelor thesis Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Study field: Medical Bioanalytics Staphylococcus aureus is a bacterium that is found in the nasal mucosa of healthy people (20-40%)...

  1. Cine club

    CERN Document Server

    Staff Association

    2015-01-01

    Wednesday 18 March 2015 at 20:00 CERN Council Chamber Funny Gmaes Directed by JMichael Haneke Austria, 1997, 108 minutes   Two seemingly well-educated young men approach a family on vacation. They are, apparently, friends of the neighbours, and, at the beginning, their true intentions are not known. But soon, the family is imprisoned and tortured in its own house violently, and the viewers are forced mostly to imagine and to share a certain complicity with the criminals. It might be some kind of game with the lives of husband, wife, son and dog, but why are they doing it? Original version german; english subtitles   Wednesday 25 March 2015 at 20:00 CERN Council Chamber La Pianiste Directed by Michael Haneke Austria/France/Germany, 2001, 131 minutes Erika Kohut is a pianist, teaching music. Schubert and Schumann are her forte, but she's not quite at concert level. She's approaching middle age, living with her mother who is domineering then submissive; Erika i...

  2. Letter of the 'Arts et Metiers' professional groups. Petroleum group, environment group; La lettre des Groupes Professionnels Arts et Metiers. Groupe Petrole, Groupe Environnement

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, A.

    2003-07-01

    The Erika tanker ship wreck (December 12, 1999) has led to direct wastes (petroleum products) and indirect wastes (oil contaminated matters and instruments) and also to a public unfriendliness towards Total oil company. This situation has led the company to mobilize exceptional means for the cleansing of the environment and the processing of wastes. The success of this operation has been possible thanks to the know-how collaboration of the petroleum (Total company) and building industry (Brezillon company) sectors, which usually do not work together in environmental activities. 270000 t of wastes have been processed in 2 years. 96 % have been cleanly recycled by washing processes. The macro wastes (4%) have been incinerated for steam/electricity generation. The argillaceous sediments have been valorized in cement industry, while the sand and rocks have been valorized as road filling materials. This short paper recalls the historical context of the Erika wreck, Total's commitments, the basic data, the physico-chemical treatment of wastes and the waste processing status. (J.S.)

  3. Developmental toxicity of PAH mixtures in fish early life stages. Part II: adverse effects in Japanese medaka.

    Science.gov (United States)

    Le Bihanic, Florane; Clérandeau, Christelle; Le Menach, Karyn; Morin, Bénédicte; Budzinski, Hélène; Cousin, Xavier; Cachot, Jérôme

    2014-12-01

    In aquatic environments, polycyclic aromatic hydrocarbons (PAHs) mostly occur as complex mixtures, for which risk assessment remains problematic. To better understand the effects of PAH mixture toxicity on fish early life stages, this study compared the developmental toxicity of three PAH complex mixtures. These mixtures were extracted from a PAH-contaminated sediment (Seine estuary, France) and two oils (Arabian Light and Erika). For each fraction, artificial sediment was spiked at three different environmental concentrations roughly equivalent to 0.5, 4, and 10 μg total PAH g(-1) dw. Japanese medaka embryos were incubated on these PAH-spiked sediments throughout their development, right up until hatching. Several endpoints were recorded at different developmental stages, including acute endpoints, morphological abnormalities, larvae locomotion, and genotoxicity (comet and micronucleus assays). The three PAH fractions delayed hatching, induced developmental abnormalities, disrupted larvae swimming activity, and damaged DNA at environmental concentrations. Differences in toxicity levels, likely related to differences in PAH proportions, were highlighted between fractions. The Arabian Light and Erika petrogenic fractions, containing a high proportion of alkylated PAHs and low molecular weight PAHs, were more toxic to Japanese medaka early life stages than the pyrolytic fraction. This was not supported by the toxic equivalency approach, which appeared unsuitable for assessing the toxicity of the three PAH fractions to fish early life stages. This study highlights the potential risks posed by environmental mixtures of alkylated and low molecular weight PAHs to early stages of fish development.

  4. Application of the Marsupial Paradigm to Tropical Cyclone Formation from Northwestward-Propagating Disturbances

    Science.gov (United States)

    Wang, Zhuo; Dunkerton, Timothy J.; Montgomery, Michael T.

    2012-01-01

    A wave-tracking algorithm is developed for northwestward-propagating waves that, on occasion, play a role in tropical cyclogenesis over the western oceans. To obtain the Lagrangian flow structure, the frame of reference is translated obliquely at the same propagation speed with the precursor disturbance. Trajectory analysis suggests that streamlines in the obliquely translated frame of reference can be used to approximate flow trajectories. The algorithm was applied to Super Typhoon Nakri (2008), Tropical Cyclone Erika (2009), and a few other examples. Diagnoses of meteorological analyses and satellite-derived moisture and precipitation fields show that the marsupial framework for tropical cyclogenesis in tropical easterly waves is relevant also for northwestward-propagating disturbances as are commonly observed in the tropical western Atlantic, the Gulf of Mexico, and the western North Pacific. Finally, it is suggested that analysis of the global model data and satellite observations in the marsupial framework can provide useful guidance on early tropical cyclone advisories.

  5. Reviews in Modern Astronomy: Vol. 17: The Sun and Planetary Systems - Paradigms for the Universe

    Science.gov (United States)

    Schielicke, Reinhard E.

    2004-09-01

    Volume 17 continues the Reviews of Modern Astronomy with fourteen invited reviews and Highlight Contributions which were presented during the International Scientific Conference of the Society on "The Sun and Planetary Systems", held at Freiburg, Germany, September 15 to 20, 2003. The Karl Schwarzschild medal 2003 was awarded to Professor Erika Boehm-Vitense, Seattle, USA. Her lecture with the title "What Hyades F Stars tell us about Heating Mechanisms in Stellar Transition Layers and Coronae" opened the meeting. The talk presented by the Ludwig Biermann-Prize winner 2003, Dr Luis R. Bellot Rubio, Freiburg i. Br., Germany, dealt with the topic "The Structure of Sunspots as Inferred from Spectropolarimetric Measurements". Other contributions to the meeting published in this volume discuss, among other subjects, solar physics, formation of planets and interferometric imaging in astronomy.

  6. Hunger in the World

    CERN Multimedia

    Ziegler,J; Vitori,J; De Baer,E

    1975-01-01

    3 exposés sont présentés par: Jean Ziegler, conseiller national et professeur de sociologie à l'université de Genève, qui dira entre autre que les riches deviennent toujours plus riches et les pauvres toujours plus pauvres...(et qu'en est-il en 2006???) Edmond Kaeser, fondateur de Terre des Hommes qui depuis 43 ans consacre son temps aux pauvres et Jacques Vitori, membre permanent de la confédération mondiale du travail. La projection d'un film tourné au Bangladesch en hiver 1974 après une très grande famine, sera commenté par Erika de Baer qui a passé plusieurs semaines au Bangladesch peu après le film.

  7. Memory, Art and Mourning: the Case of the 'Salón del Nunca Más' of Granada (Antioquia, Colombia

    Directory of Open Access Journals (Sweden)

    Elkin Rubiano Pinilla

    2017-07-01

    Full Text Available This document examines the work produced in the 'Salón del Nunca Más', located in Granada (Antioquia on the subject of collective memory. In this rural town, the 'Salón' has articulated different practices that, along with the construction of memory, have allowed survivors of violence and family members of killed and disappeared individuals to symbolize loss by means of public rituals. On the other hand, the article explores the visual settings that lay down the event, not only the exposure of violent events but the practices of the local community: what happens in the 'Salón', the journalistic covering (written press, the documental photography (Jesús Abad Colorado and the artistic work (Erika Diettes. For this purpose, archival material, a historical interdisciplinary approach, psychoanalysis and image and communication theories, as well as interviews is referenced through this article.

  8. Reliability generalization of the Multigroup Ethnic Identity Measure-Revised (MEIM-R).

    Science.gov (United States)

    Herrington, Hayley M; Smith, Timothy B; Feinauer, Erika; Griner, Derek

    2016-10-01

    [Correction Notice: An Erratum for this article was reported in Vol 63(5) of Journal of Counseling Psychology (see record 2016-33161-001). The name of author Erika Feinauer was misspelled as Erika Feinhauer. All versions of this article have been corrected.] Individuals' strength of ethnic identity has been linked with multiple positive indicators, including academic achievement and overall psychological well-being. The measure researchers use most often to assess ethnic identity, the Multigroup Ethnic Identity Measure (MEIM), underwent substantial revision in 2007. To inform scholars investigating ethnic identity, we performed a reliability generalization analysis on data from the revised version (MEIM-R) and compared it with data from the original MEIM. Random-effects weighted models evaluated internal consistency coefficients (Cronbach's alpha). Reliability coefficients for the MEIM-R averaged α = .88 across 37 samples, a statistically significant increase over the average of α = .84 for the MEIM across 75 studies. Reliability coefficients for the MEIM-R did not differ across study and participant characteristics such as sample gender and ethnic composition. However, consistently lower reliability coefficients averaging α = .81 were found among participants with low levels of education, suggesting that greater attention to data reliability is warranted when evaluating the ethnic identity of individuals such as middle-school students. Future research will be needed to ascertain whether data with other measures of aspects of personal identity (e.g., racial identity, gender identity) also differ as a function of participant level of education and associated cognitive or maturation processes. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  9. An investigation of the stable isotopes, geochemistry and morphology of major streams in Dominica, Lesser Antilles: 2014 - 2017

    Science.gov (United States)

    Kopas, D. C.; Joseph, E. P.; Frey, H. M.

    2017-12-01

    The island of Dominica is a recently active (pH and temperature, were recorded and water samples taken and analyzed for alkalinity, major elements (cations and anions), trace elements and stable isotopes (carbon, deuterium, and oxygen). Variations in water chemistry and river morphology were compared to various parameters, including precipitation, landslide locations, and lithology for each of the catchments. Within the study period, on August 27th, 2015, a significant tropical storm, Erika, made landfall in Dominica, depositing more than 500 mm of rainfall in 10 hours. There was little infiltration of the rainwater (over 50-60% run-off), which resulted in significant landslides, flash floods and damage to infrastructure and loss of life. Despite the obvious morphologic changes to the streams and high discharge during the storm event, preliminary analysis has shown little change in major stream geochemistry following the passage of Tropical Storm Erika. The 10-month time gap between the storm and the post-storm field sampling in June 2016 may be a factor of why geochemical changes were not observed. One of the most significant variations of stream composition during the study period was annual shifts in δD between -1.3 to -5.8 ‰ and δ18O between -1.98 to -2.61 ‰. A possible factor influencing the δ18O of surface waters is seasonal variation in rainfall. The dominant control on precipitation δ18O values is the amount effect, whereby rainfall amount and δ18O are inversely correlated. This relationship is a proxy for changes in δ18O values of surface waters. The data also suggest that hydrothermal fluids are not a prominent contributor to Dominican rivers, despite the presence of active volcanism and numerous hydrothermal systems on the island. The exceptions are the White River, which drains the Valley of Desolation and Boiling Lake and the Lamothe River, which drains the Cold Soufrierre.

  10. L’aggressività della coppia criminale: la strage di Erba analizzata nell’ottica della coscienza intersoggettiva di D. Stern/L'agressivité des couples criminels : le massacre de Erba analysé par l'approche de la conscience intersubjective de Daniel Stern/The agressiveness of the criminal couples: the analysed massacre of Erba using the approach of the intersubjective conscience of Daniel Stern

    Directory of Open Access Journals (Sweden)

    Pasquale Caponnetto

    2013-12-01

    Full Text Available La coppia criminale è un fenomeno poco comune nell'ambito dei delitti in quanto la maggior parte dei criminali commette il crimine da solo o coinvolge altri individui solo per caso. Ciò nonostante, la letteratura rivela una serie di coppie criminali che hanno commesso diversi crimini, fino ad arrivare all’omicidio. Alcuni hanno ucciso per denaro, altri per odio, altri ancora per amore, per vendetta, per perversione. Bonnie e Clyde, Olindo e Rosa, Erika e Omar sono espressione di un viaggio nel fenomeno del “crimine di coppia” in cui manifestazioni di follia a due, al di là dell’infatuazione reciproca e della dipendenza psicologica, si svuotano di qualsiasi accezione romantica per concretizzarsi in qualcosa di spaventoso e incontenibile, capace di sfuggire ad ogni tipo di catalogazione e comprensione. Nel presente lavoro, in particolare, si andrà ad analizzare la coppia criminale degli autori della strage di Erba, che verrà esaminata nell’ottica della coscienza intersoggettiva di Stern. Le couple criminel est un phénomène rare puisque la majorité des crimes sont commis par des criminels seuls ou ce n’est que par hasard qu’ils impliquent d’autres personnes. Toutefois, la littérature parle d’une série de couples criminels qui ont commis des différents types de crimes (homicide inclus. Certains d’entre eux tuent pour de l’argent, certains autres à cause de la haine, de l’amour, de la revanche ou de la perversion. Bonnie et Clyde, Olindo et Rosa, Erika et Omar constituent des exemples du phénomène du « crime en couple ». Ce sont des situations de folie à deux qui n’ont aucune acception romantique et qui se traduisent en quelque chose d’horrifiant et d’incontrôlé. Dans cet article, les auteurs vont analyser le couple criminel composé par les responsables du massacre de Erba (Italie du Nord. L’objectif est d’examiner ce couple en utilisant l’approche de la conscience intersubjective de Daniel

  11. On the Contribution of Slovenian Linguistics to the History of the Ancient Greek Perfect

    Directory of Open Access Journals (Sweden)

    Jerneja Kavčič

    2010-12-01

    Full Text Available An important contribution to the history of the Ancient Greek perfect is the study of Erika Mihevc-Gabrovec, The Disappearance of the Perfect in Late Greek (La disparition du parfait dans le grec de la basse époque. In terms of theory and content, her study continues the work of Pierre Chantraine, but somewhat diverges from her predecessor’s views on the issue of the merger between the aorist and the perfect, identifying examples of the use of the perfect even in an – according to Pierre Chantraine – relatively late period.  Some years after the publication of Erika Mihevc-Gabrovec’s book, the question of when the aorist and the perfect may have merged was raised again, to be addressed by McKay in a number of articles. Today, the views on the subject are strongly divided.   As argued by the author of this paper, one of the setbacks in examining the merger between the aorist and the perfect concerns the methodology, since researchers have tended to rely exclusively on their sense of language. A possible new approach is offered in the framework of the Slovenian theory of Natural Syntax, which has from the start paid considerable attention to English sentences of the I believe her to be intelligent type. The paper describes similar sentences in New Testament Greek, terming them “sentences of the λέγουσινἀνάστασινμὴεἶναι type”. In New Testament Greek, they display a tendency to use the present infinitive of stative verbs; relatively frequent is also the perfect infinitive (of non-stative verbs, while, as already noted in other studies, these sentences – at least in New Testament Greek – avoid the aorist infinitive. Such sentences thus bear witness to the fact that the aorist and the perfect were not fully interchangeable in New Testament Greek; the status of the aorist and perfect infinitives in sentences of the λέγουσινἀνάστασινμὴεἶναι type should also be taken into

  12. Uranium Exploration in Paipa and Iza Area, Colombia: A Preliminary Report of New Contributions

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez-Oviedo, L., E-mail: leogonza@ingeominas.gov.co [Mineral Resources Area — INGEOMINAS, Bogotá (Colombia)

    2014-05-15

    This paper shows the preliminary results from uranium exploration of the Boyacá Department, for the first survey conducted by the Colombian state after 26 years. The exploration was carried out this year and the zone covers an area of 460 square kilometers divided into three sectors, located in the municipalities of Sogamoso Paipa, Iza, Tota and Pesca, Chivata and Tuta. The area is dominated by Cretaceous-Tertiary sedimentary rocks Quaternary sediments. Paipa and Iza exposes outcrops volcanic and sedimentary rocks; and the major structural features are Arcabuco anticline, Los Medios syncline and Boyaca and Soapaga faults. The sedimentary formations from the oldest to most recent in the area are: Tibasosa Formation; Une Formation, Conejo Formation; Plaeners Formation; Los Pinos Formation; Labor y Tierna Formation, Guaduas Formation Socha Formation; Picacho Formation an Concentration Formation; in the area outcrops also, volcanic rocks (rhyolites porphyrites and andesites); and explosive (pumices). In the Paipa Area, three anomalous sites (Durazno, Quebrada Honda and Casa Blanca) were found with values ranging between 440 and 7 500 counts/s, the highest values were reported in the Durazno area. The host rocks are volcanic rocks (tophus) and tectonic breccias with thin strips of coal from the Guaduas Formation. In 1979 the studies by ENUSA (Spain) reported values up to 3 800 counts/s. In Iza, five anomalous zones (El Crucero, San Miguel, Cuitiva — Iza, Erika and Tota — Pesca) was found with values ranging between 480 and 4 480 counts/s. Host rocks are igneous rocks in Erika sector; and phosphates in El Crucero sector with a maximum value of 2 100 counts/s. In shot holes made in Iza the values went up from 1 200 counts/s in surface to 4 480 counts/s in depth (1.60 m). In Paipa, the values incerased from 4 500 in surface to 7 500 counts/s at 1.50 meters. Chemical analysis, of samples from “El Durazno” records values between 200 and 5 345 ppm so that this year

  13. Identidade cultural e globalização em produções artísticas contemporâneas

    Directory of Open Access Journals (Sweden)

    Lurdi Blauth

    2015-10-01

    Full Text Available O presente estudo aborda alguns aspectos sobre identidade cultural e globalização, a partir das proposições poéticas dos artistas Javier & Erika, destacando as obras Inforncof e Haciendo Mercado, que foram apresentadas na 8ª Bienal do Mercosul, em 2011. Essas obras propõem reflexões críticas sobre a questão da identidade cultural da América Latina do póscolonialismo, apontando as diferenças reais e simbólicas presentes na cultura paraguaia, em oposição às tradições indígenas e práticas capitalistas. O aporte teórico articula o pensamento de Nestor Garcia Canclini sob a perspectiva da globalização em suas esferas política, econômica e cultural, problematizando a ampliação do horizonte local e nacional. Stuart Hall trata a questão da identidade no contexto social e cultural, cujas rápidas mudanças, se não houver adaptação, instauram a crise de identidade pelo descentramento, deslocamento e também a sua fragmentação. ABSTRACT The present paper approaches some aspects regarding cultural identity and globalization, out of poetical propositions of the artists Javier & Erika, emphasizing the works Inforncof e Haciendo Mercado, presented at the Mercosul 8th Biennial, in 2011. Those works propose critic reflexions on the post-colonialism Latin America cultural identity matter, pointing to the real and the symbolic differences present in Paraguayan culture, in opposition to the indigenous traditions and capitalist practices. The theoretical basis articulates the thought of Nestor Garcia Canclini under the globalization perspective, in its political, economical and cultural spheres, questioning the local and national horizon broadening. Stuart Hall discusses the matter of identity in the social and cultural context, whose fast changes, if there is no adaptation, create an identity crisis through its destabilization, displacement and fragmentation. KEYWORDS Culture, cultural identity, globalization, contemporary art.

  14. Selecting of a cytochrome P450cam SeSaM library with 3-chloroindole and endosulfan - Identification of mutants that dehalogenate 3-chloroindole.

    Science.gov (United States)

    Kammoonah, Shaima; Prasad, Brinda; Balaraman, Priyadarshini; Mundhada, Hemanshu; Schwaneberg, Ulrich; Plettner, Erika

    2018-01-01

    Cytochrome P450 cam (a camphor hydroxylase) from the soil bacterium Pseudomonas putida shows potential importance in environmental applications such as the degradation of chlorinated organic pollutants. Seven P450 cam mutants generated from Sequence Saturation Mutagenesis (SeSaM) and isolated by selection on minimal media with either 3-chloroindole or the insecticide endosulfan were studied for their ability to oxidize of 3-chloroindole to isatin. The wild-type enzyme did not accept 3-chloroindole as a substrate. Mutant (E156G/V247F/V253G/F256S) had the highest maximal velocity in the conversion of 3-chloroindole to isatin, whereas mutants (T56A/N116H/D297N) and (G60S/Y75H) had highest k cat /K M values. Six of the mutants had more than one mutation, and within this set, mutation of residues 297 and 179 was observed twice. Docking simulations were performed on models of the mutant enzymes; the wild-type did not accommodate 3-chloroindole in the active site, whereas all the mutants did. We propose two potential reaction pathways for dechlorination of 3-chloroindole. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared Goldstone. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Teatr czy literatura? O literaturoznawczej teorii teatru

    Directory of Open Access Journals (Sweden)

    Marta Karasińska

    2007-04-01

    Full Text Available This work undertakes the problem of philological reflection on theatre, placing in the centre of considerations the relations between the word and the stage. Often criticised for its onesidedness, the reflection of specialists in literary studies focuses modern scholars around two leading methodologies - that of semiology and that of phenomenology. In the article the author adduced some selected works of Western theorists - the classic book by Anne Ubersfeld "Reading Theatre", which is a lucid example of "a literary theory of theatre", which in fact ignores the specificity of stage art, and the publications which fo llow the semiological route and are the work of such well-known theatrologists as Erika Fischer Lichte, Keir Elam and Martin Esslin. The philological point of view adopted in these works causes either granting literature a dominant role with respect to theatre, or, in turn, makes it that both disciplines are treated as beings which have been artificially separated, devoid of any relationships. The works mentioned here are the proof of limitations and shortages of the semiological method, which is positively tested exclusively as a tool of the description of a performance and which is always incapable of making over-all attempts to look at a performance and at its semantics.

  16. European Atlantic: the hottest oil spill hotspot worldwide

    Science.gov (United States)

    Vieites, David R.; Nieto-Román, Sandra; Palanca, Antonio; Ferrer, Xavier; Vences, Miguel

    2004-11-01

    Oil spills caused by maritime transport of petroleum products are still an important source of ocean pollution, especially in main production areas and along major transport routes. We here provide a historical and geographic analysis of the major oil spills (>700 t) since 1960. Spills were recorded from several key marine ecosystems and marine biodiversity hotspots. The past four decades have been characterized by an overall decrease in the number of accidents and tonnes of oil spilled in the sea, but this trend was less distinct in the European Atlantic area. Recent black tides from the Erika and Prestige vessels provided new evidence for the high risk of accidents with serious ecological impact in this area, which according to our analysis is historically the most important oil spill hotspot worldwide. The English Channel and waters around Galicia in Spain were the areas with most accidents. Maritime transport in European Atlantic waters has been predicted to continue increasing. Together with our own results this suggests that, in addition to measures for increased traffic safety, deployment of emergency capacities in the spill hotspot areas may be crucial for a sustainable conservation of sea resources and ecosystems.

  17. Perspectives on the clinical significance of functional pain syndromes in children

    Directory of Open Access Journals (Sweden)

    Basch MC

    2015-10-01

    Full Text Available Molly C Basch,1,2 Erika T Chow,1,3 Deirdre E Logan,1,4 Neil L Schechter,4 Laura E Simons1,2,4 1Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children's Hospital, 2Boston Children's Hospital, Center for Pain and the Brain, PAIN Research Group, 3Boston University School of Medicine, Boston University, 4Department of Psychiatry, Harvard Medical School, Boston, MA, USA Abstract: Functional pain syndromes (FPS characterize a subset of individuals who experience pain and related symptoms and disability without clear structural or disease etiology. In the pediatric population, FPS hold high clinical importance due to significant prevalence rates and potential to persist into adulthood. Although extensive research has been executed to disambiguate FPS, the syndromes that fall within its spectrum remain conceptually complex and sometimes ill-defined. This paper provides an overview of available research on the classification and multifaceted etiology of FPS in youth and their effects on interpersonal, psychological, and familial function. Vital aspects of a successful multidisciplinary approach to treating this population are described; however, it is evident that future research requires more longitudinal studies. Keywords: overlapping chronic pain, functional pain, primary pain disorders, pediatrics, biopsychosocial model

  18. Accidental pollution in the ocean: besides crude oil, chemicals and other spills

    International Nuclear Information System (INIS)

    Marchand, M.

    2003-01-01

    Accidental pollution of the seas is usually illustrated by the shipwreck of tankers carrying crude oil. We must look beyond this image since such accidents spill substances other than petrochemicals. We need but mention the Levoli Sun's accident near the Cotentin peninsula, France, one year after the Erika went down. And what about spills of agricultural and food products? An accidental spill as apparently harmless as wheat might have serious effects on not just the environment but also human health. In all cases, two major series of questions crop up: 1) Is it necessary to intervene? If so, are we able to? And if we can, how to fight against spills? 2) What are the short- and long-term effects on the environment and on all human activities related to the sea (fishing, fish-farming, salt production, tourism, salt-water cures, etc.)? These two questions have a common denominator: the need to know how spilled products react. This knowledge conditions both the operational response for fighting against pollution and the assessment of the impact on the maritime environment. (author)

  19. Events - France. Stock exchange. International; Actualite - France. Bourse. International

    Energy Technology Data Exchange (ETDEWEB)

    Anon,

    2000-10-01

    These columns made of short articles report on facts and events in the oil and gas industry in France and worldwide: 1 - France: increase of the production capacity of the ethylene oxide unit of BP's Lavera plant; the 'Plateaux-du-Vexin' gas pipeline crosses the Seine river; completion of the pumping of the front wreckage of the Erika tanker ship; Total inaugurates a vapor recovery unit at the Gonfreville l'Orcher refinery; a national energy saving plan for the abatement of the greenhouse effect; Sercel, a daughter company of Compagnie Generale de Geophysique (CGG), acquires Mark Products division of Shaw industries; the oil prices shoot the international trade; 2 - stock exchange: trend of market values in the context of oil crisis; 3 - international: important oil and gas strike made by TotalFinaElf and OKIOC (Offshore Kazakhstan International Operating Company) in Kazakhstan; communication: a new look for BP; status of Lukoil reserves in Russia; next round for the exploration of the Norwegian North Sea; Transocean Sedco Forex absorbs R and B Falcon Corp and becomes the first drilling contractor; ENI (Italy) becomes operator on the development of South Pars gas field (Iran) for the phases 4 and 5; Shell Overseas Investments BV, BP and Exxon Mobil have signed strategic alliance agreements with China Petroleum and Chemical Corp (Sinopec); first exploration permits for the Faeroe islands; different gas pricing rules for the industrialists in the different European countries. (J.S.)

  20. Psychotherapeutic intervention by telephone

    Directory of Open Access Journals (Sweden)

    Erika Mozer

    2008-06-01

    Full Text Available Erika Mozer1,2, Bethany Franklin1,3, Jon Rose11Department of Veterans Affairs, Palo Alto Health Care System, Palo Alto, CA, USA; 2PGSP Stanford PsyD Consortium Palo Alto, CA, USA; 3Pacific Graduate School of Psychology Palo Alto, California, USAAbstract: Psychotherapy conducted over the telephone has received increasing amounts of empirical attention given practical advantages that side-step treatment barriers encountered in traditional office-based care. The utility and efficacy of telephone therapy appears generalizable across diverse clinical populations seeking care in community-based hospital settings. Treatment barriers common to older adults suggest that telephone therapy may be an efficient and effective mental health resource for this population. This paper describes empirical studies of telehealth interventions and case examples with psychotherapy conducted via telephone on the Spinal Cord Injury Unit of the Palo Alto Veterans’ Administration. Telephone therapy as appears to be a viable intervention with the aging population.Keywords: telehealth, rural mental health, psychotherapy, healthcare delivery, telecare

  1. Víctimas del arte: Reflexiones en torno a la representación de la guerra en Colombia

    Directory of Open Access Journals (Sweden)

    Alejandro Gamboa

    2016-04-01

    Full Text Available Pocos temas son tan delicados y problemáticos de representar como el de la memoria de la guerra: cúmulos de testimonios, imágenes y relatos presentan al artista-investigador un reto formal, epistémico y ético. Usando como ejemplo la instalación titulada Sudarios, realizada por la artista colombiana Erika Diettes (Cali, 1978, este artículo reflexiona sobre el actual “boom” de prácticas artísticas que representan la guerra en Colombia. Se argumentará que las lógicas del “repudio a la guerra” y el “homenaje a las víctimas”, vehiculadas acríticamente por algunas obras de arte, pueden estar re-produciendo formas de subjetividad en la que toda identidad es aplanada, donde la historia es suspendida y los conflictos pospuestos. Así, suprimir la complejidad del fenómeno de la guerra (con sus determinaciones económicas, políticas, históricas, ideológicas, entre otros estaría propiciando el despliegue de sentimientos morales que pueden ser absorbidos por el poder hegemónico.

  2. New tools and technologies to manage operational data and help in decision-making concerning shoreline pollution

    International Nuclear Information System (INIS)

    Gouriou, V.; Quintin, K.; Legrand, S.; Mazurier, A.; Le Junter, Y.; Gicquel, M.

    2006-01-01

    This paper addressed the issue of effectively collecting and organizing all data related to an oil spill. It referred to lessons learned from the Erika and Prestige oil spills which polluted the French coastal waters. A user-friendly tool for data management and storage for shoreline pollution was developed following the 2 incidents. The tool was developed under the auspices of the Argepol project and has helped response teams and decision-makers use web technologies and interactive cartography to access, capture and make use of data about shoreline landings, collected waste, disposed waste, manpower, equipment requirements, evolution of the spill and cleaning. The tool has allowed maximum flexibility regarding connections and possible adaptations to other systems, particularly foreign ones. A prototype was tested and validated by simulating an exercise involving the marine pollution (POLMAR) response teams. The tool allows users to create and edit geographical information online, modify databases and shore information using a web browser. Improvements are still in progress and regular updates are scheduled in order to keep the tool in use for the long term. 11 refs., 6 figs

  3. Events - France. Stock exchange. International; Actualite - France. Bourse. International

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2000-10-01

    These columns made of short articles report on facts and events in the oil and gas industry in France and worldwide: 1 - France: increase of the production capacity of the ethylene oxide unit of BP's Lavera plant; the 'Plateaux-du-Vexin' gas pipeline crosses the Seine river; completion of the pumping of the front wreckage of the Erika tanker ship; Total inaugurates a vapor recovery unit at the Gonfreville l'Orcher refinery; a national energy saving plan for the abatement of the greenhouse effect; Sercel, a daughter company of Compagnie Generale de Geophysique (CGG), acquires Mark Products division of Shaw industries; the oil prices shoot the international trade; 2 - stock exchange: trend of market values in the context of oil crisis; 3 - international: important oil and gas strike made by TotalFinaElf and OKIOC (Offshore Kazakhstan International Operating Company) in Kazakhstan; communication: a new look for BP; status of Lukoil reserves in Russia; next round for the exploration of the Norwegian North Sea; Transocean Sedco Forex absorbs R and B Falcon Corp and becomes the first drilling contractor; ENI (Italy) becomes operator on the development of South Pars gas field (Iran) for the phases 4 and 5; Shell Overseas Investments BV, BP and Exxon Mobil have signed strategic alliance agreements with China Petroleum and Chemical Corp (Sinopec); first exploration permits for the Faeroe islands; different gas pricing rules for the industrialists in the different European countries. (J.S.)

  4. Self-similar distribution of oil spills in European coastal waters

    International Nuclear Information System (INIS)

    Redondo, Jose M; Platonov, Alexei K

    2009-01-01

    Marine pollution has been highlighted thanks to the advances in detection techniques as well as increasing coverage of catastrophes (e.g. the oil tankers Amoco Cadiz, Exxon Valdez, Erika, and Prestige) and of smaller oil spills from ships. The new satellite based sensors SAR and ASAR and new methods of oil spill detection and analysis coupled with self-similar statistical techniques allow surveys of environmental pollution monitoring large areas of the ocean. We present a statistical analysis of more than 700 SAR images obtained during 1996-2000, also comparing the detected small pollution events with the historical databases of great marine accidents during 1966-2004 in European coastal waters. We show that the statistical distribution of the number of oil spills as a function of their size corresponds to Zipf's law, and that the common small spills are comparable to the large accidents due to the high frequency of the smaller pollution events. Marine pollution from tankers and ships, which has been detected as oil spills between 0.01 and 100 km 2 , follows the marine transit routes. Multi-fractal methods are used to distinguish between natural slicks and spills, in order to estimate the oil spill index in European coastal waters, and in particular, the north-western Mediterranean Sea, which, due to the influence of local winds, shows optimal conditions for oil spill detection.

  5. Hurricane Imaging Radiometer (HIRAD) Wind Speed Retrievals and Assessment Using Dropsondes

    Science.gov (United States)

    Cecil, Daniel J.; Biswas, Sayak K.

    2018-01-01

    The Hurricane Imaging Radiometer (HIRAD) is an experimental C-band passive microwave radiometer designed to map the horizontal structure of surface wind speed fields in hurricanes. New data processing and customized retrieval approaches were developed after the 2015 Tropical Cyclone Intensity (TCI) experiment, which featured flights over Hurricanes Patricia, Joaquin, Marty, and the remnants of Tropical Storm Erika. These new approaches produced maps of surface wind speed that looked more realistic than those from previous campaigns. Dropsondes from the High Definition Sounding System (HDSS) that was flown with HIRAD on a WB-57 high altitude aircraft in TCI were used to assess the quality of the HIRAD wind speed retrievals. The root mean square difference between HIRAD-retrieved surface wind speeds and dropsonde-estimated surface wind speeds was 6.0 meters per second. The largest differences between HIRAD and dropsonde winds were from data points where storm motion during dropsonde descent compromised the validity of the comparisons. Accounting for this and for uncertainty in the dropsonde measurements themselves, we estimate the root mean square error for the HIRAD retrievals as around 4.7 meters per second. Prior to the 2015 TCI experiment, HIRAD had previously flown on the WB-57 for missions across Hurricanes Gonzalo (2014), Earl (2010), and Karl (2010). Configuration of the instrument was not identical to the 2015 flights, but the methods devised after the 2015 flights may be applied to that previous data in an attempt to improve retrievals from those cases.

  6. Regional-scale analysis of subtidal rocky shore community

    Science.gov (United States)

    Derrien-Courtel, Sandrine; Le Gal, Aodren; Grall, Jacques

    2013-12-01

    The French monitoring network, REseau BENThique (REBENT), was launched by the Ministry of the Environment in 2003 following the 1999 Erika oil spill. REBENT aimed to acquire baseline knowledge of coastal benthic habitat distributions with a special focus on biological diversity. This study analyzed data from 38 subtidal rocky reef sites collected by a single diving team of marine biologists along the coast of Brittany from 2004 to 2010. At each site, the depth limits of the algal belts were determined between 0 and -40 m Chart Datum (CD); the flora and fauna compositions and abundances were sampled at -3 and -8 m CD. A total of 364 taxa (156 flora and 208 fauna), belonging to 12 phyla, were identified. The results showed that the depth limit and density of kelp beds increased as water turbidity decreased; moreover, several changes in community structure could be related to water turbidity and temperature. Thus, northern and southern Brittany showed strong differences in diversity and structure of the dominant kelp species ( Laminaria hyperborea and Saccorhiza polyschides). The results from this kelp habitat composition survey (dominant kelp species and indicator species) provided important information for local pressure assessments, like increases in turbidity. The data also provided a reference that could be useful for detecting changes in coastal water temperatures due to global warming.

  7. Eesti kunsti näitused Ameerikas

    Index Scriptorium Estoniae

    2006-01-01

    23. II-12. III New Yorgis ÜRO peakorteris näitus "Käemaastikud/Handscapes". Vaadata on fotod, maalid ja installatsioonid. Kuraator Elin Kard, osalevad Jüri Ojaver, Ülle Marks, Jüri Kass, Alice Kask. 24. III-21. IV New Yorgi Eesti Majas Eesti Kultuurifondi ja Eesti kultuuripäevade näitus "Lõõm 06. Kunstidialoog: New York - Estonia". Jaanika Peerna kureeritud näitusel osalevad eesti ja ameerika kunstnikud Peeter Kolk, Dianne Bowen, Külliki Talp, Ilse Leetaru, Mark Kostabi, Paul Indrek Kostabi, Kristjan Jüris, Erika Roots, Endel Uiga, J. Peerna, Victoria Schultz, Leevi Ernits, Kristiana Pärn, Naima Rauam, Patrick Kikut, Ave Barker, Epp Kuhn, Triinu Jenas. Avamisel esilinastub J. Peenra ja Annette Solakoglu (sünd. 1968, Rootsi) lühifilm "Lõõm 06". Phoenixi Cathedral Center for the Artsis oli 3. II-1. III Anne Parmasto maalinäitus Charlotte'i aed"

  8. Falling in love with minerals terra mineralia - a journey to the most beautiful minerals of the world

    Science.gov (United States)

    Anna, D.

    2013-12-01

    Is it possible to make people fall in love with minerals? Yes, it is. And it happens daily at terra mineralia, a permanent exhibition displaying a collection of 3500 rare and beautiful minerals, precious stones and meteorites in Freiberg/Saxony. The exhibits are part of one of the world's largest private collections of minerals and have been given to the TU Bergakademie Freiberg on permanent loan by Dr. Erika Pohl-Ströher. The exquisite pieces stem from sites on every continent, and as such, allow the visitor to virtually journey around the world to the world's most beautiful minerals - an amazing and unexpected experience. The specimen are so unique in quality and aesthetical appearance that scientists and private collectors from all over the world are overwhelmed by their display. However, the exhibition is less targeted towards the specialist or collector. Due to the close ties of the terra mineralia to its parent organization, the TU Bergakademie Freiberg, which is one of the leading universities dedicated to the geo-sciences, it has been primarily designed to attract young visitors, school children and students. It is the expressed goal of the University and Dr. Erika Pohl-Ströher to give young people the opportunity to discover the fascinating aspects natural sciences have to offer. Therefore, the efforts of the museums educational service focus on raising awareness and enticing the young 'scientists' to be. Why not continue a live of learning where the interest in natural sciences had been nurtured in first place - at the TU Bergakademie in Freiberg, for example with studies in the fields of mineralogy, geology or mining? And while you are at it, come back to terra mineralia as a student to help form and train the next generation of young talents. So, does it work? Yes, even if it is still too early to see the young enrolled in the University. What we already see, is a tremendous amount of positive feed back from the young, their parents and educators

  9. Dissertation Notice: A Grammar of Wutun

    Directory of Open Access Journals (Sweden)

    Reviewed by Benjamin Brosig

    2018-05-01

    Full Text Available Erika Sandman. 2016. A Grammar of Wutun. Helsinki: University of Helsinki. Doctoral dissertation, xii, 370 p. [http://bit.ly/2C0jMCY, accessed 13 December 2017]. An occasional problem when doing research on the languages of northern China is that while there are medium-sized structuralist, historical, and contemporary grammars for many local non-Sinitic varieties (e.g., Todaeva 1966, Chen and Cinggeltei 1986, and Fried 2010 for Bonan, the same does not seem to be equally true for their Sinitic contact varieties. A Grammar of Wutun, a dissertation written by Erika Sandman at the two departments of World Culture and Modern Languages at the University of Helsinki, helps close this gap for what has since Chen (1981 been known as one of the most idiosyncratic varieties of North-Western Mandarin. This language formed as part of the Amdo Sprachbund in intensive contact with Amdo Tibetan and, to some extent, Qinghai Bonan. A Grammar of Wutun is based on Basic Linguistic Theory (Dixon 1997, 2010 and tends to make use of well-established classics for individual linguistic domains (e.g., Lamprecht 1994 for information structure, Yap et al. 2011 for nominalization. Based on a corpus of approximately 1,300 naturally attested and 1,100 elicited clauses mostly collected by the author herself, it first describes the sociolinguistic and research context (1-18, the phonology (19-41, following Janhunen et al. 2008 and word classes (42-175, nouns, verbs, minor of Wutun. After attested morphological forms are thus accounted for, it continues by describing functional domains such as aspect (176-205; evidentiality and egophoricity (206-239; clausal word order, valency, and information structure (240-286; clause-type-related morphological mechanisms for interrogating, ordering, and negating (287-310; and clause connection (311-348. The book closes with glossed and translated transcriptions of three short procedural monologues (349-361. In the nominal domain, Wutun

  10. «СССР на стройке» la vetrina europea di Stalin

    Directory of Open Access Journals (Sweden)

    Marta Valeri

    2015-01-01

    Full Text Available The magazine “SSSR na stroike” (“USSR in Construction” published in Russia, Germany, France, England was born in the early 1930s from an idea of Maksim Gorky. It was conceived as the successor of another well-known issue, “Nashi dostizhenia” to let the whole Europe know about the progress and successes of the First Five-Year Plan and of the related Soviet system. Beyond the propaganda, “SSSR na stroike” had another main task: opposing the negative image the Russians émigrés gave of their native country abroad. Official portraitists by the Soviet élite, photographers, intellectuals and artists with whose works USSR celebrated and created their own myths were chosen to realize this project. That way, new Soviet idols became the peasants from the series “24 hours at the Filippov’s” and the workers of “The Giant and the Builder”. The circulation of the magazine abroad could count on the help of foreign estimators of the Soviet model, who personally acted to spread these images, while in Russia the editor Pjatakov and valuable artists, such as A. Rodchenko, assured success and the quality of the content. So far research has focused on the graphic and artistic aspects of the magazine, mainly thanks to the studies of Erika Wolf, Professor of Art and Visual Culture at the University of Otago, while the historical, cultural and political importance of the magazine was marginally analyzed. It will be interesting to highlight language choices and editorial strategies used for such an issue, which should offer the internal élite a window on a changing country, while it should be a real shop window for estimators, foreign investors, simple spectators and also those who oppose the realization of the Soviet utopia in USSR.

  11. Book review. Manuale di ematologia veterinaria e medicina trasfusionale. (a cura di Magda Gerou-Ferriani

    Directory of Open Access Journals (Sweden)

    Manuel Graziani

    2013-09-01

    Full Text Available Il volume curato dalla dott.ssa Magda Gerou-Ferriani dell'Ospedale veterinario "Portoni Rossi" di Bologna e dell'Università di Liverpool viene presentato come il primo manuale di ematologia veterinaria italiano. Un volume realizzato per essere utilizzato dagli studenti e dai veterinari nella pratica quotidiana. Da qui deriva la scelta della sua struttura organizzata per capitoli autonomi in modo che il lettore possa consultare le tematiche di proprio interesse indipendentemente dal resto. I primi due capitoli del manuale sono dedicati alle nozioni di base e forniscono informazioni concrete per ciò che riguarda i prelievi del sangue nella pratica veterinaria, l'allestimento e la corretta lettura del vetrino e tutto quanto è necessario sapere sulle trasfusioni. Nel terzo capitolo viene illustrata nel dettaglio l'interpretazione dell'eritrogramma, del leucogramma e del siderogramma. A seguire, nei capitoli 4 e 5, vengono trattate le patologie più spesso riscontrate dei globuli rossi, dei globuli bianchi e delle piastrine. Il sesto capitolo è dedicato alla coagulazione, un argomento spesso difficile da comprendere e da applicare, vengono illustrati i vari test, quando e come eseguirli ed interpretarli. Il manuale si conclude con un capitolo dedicato all'interpretazione dell'esame del midollo e con l'ultimo capitolo che contiene esempi pratici di casi clinici. Manuale di ematologia veterinaria e medicina trasfusionale è un testo pratico, di facile consultazione, ben curato sia sotto l'aspetto della presentazione dei contenuti che sotto l'aspetto editoriale: dal grande formato A4, alla copertina rigida. Alla curatrice Magda Gerou-Ferriani sono affiancati come autori Erika Carli, Stefano Comazzi, Silvia Tasca e Andrea Zoia, tutti medici veterinari.

  12. Critical appraisal of the use of regorafenib in the management of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Festino L

    2013-04-01

    Full Text Available Lucia Festino*, Alessio Fabozzi*, Anna Manzo, Valentina Gambardella, Erika Martinelli, Teresa Troiani, Ferdinando De Vita, Michele Orditura, Fortunato Ciardiello, Floriana Morgillo Division of Medical Oncology, Department of clinical and experimental medicine and surgery "F. Magrassi e A. Lanzara", Second University of Naples, Napoli, Italy*These authors contributed equally to this work Abstract: The lack of valid clinical management options for patients affected by metastatic colorectal cancer, which has progressed after all approved standard treatments, has lead to research into new active molecules. Regorafenib is an oral small-molecule multi kinase inhibitor, binding to several intracellular kinases, with powerful inhibitory activity against vascular endothelial growth factor receptors (VEGFR-1,VEGFR-2, and VEGFR-3, platelet-derived growth factor receptor, fibroblast growth factor receptor 1, Raf, TIE-2, and the kinases KIT, RET, and BRAF. The antitumor activity of regorafenib has been tested in vitro and in vivo, and inhibition of tumor growth has been observed in several cancer models, particularly colorectal cancer and gastrointestinal stromal tumors. The most frequent adverse events of grade 3 or higher related to regorafenib were hand-foot skin reaction, fatigue, diarrhea, hypertension, and rash or desquamation. Only a few Phase I–II trials, and most recently a Phase III trial in pretreated colorectal cancer, have been carried out to date. Several ongoing trials are testing the efficacy of regorafenib in combination with chemotherapy. At this point in time, regorafenib is the first small-molecule tyrosine kinase inhibitor to gain approval by the US Food and Drug Administration for pretreated metastatic colorectal cancer patients. Keywords: colorectal cancer, angiogenesis, regorafenib

  13. MEKANISME KETAHANAN KENTANG (SOLANUM TUBEROSUM TERHADAP NEMATODA SISTA KUNING (GLOBODERA ROSTOCHIENSIS

    Directory of Open Access Journals (Sweden)

    Dewi Fitriyanti, Mulyadi, dan Christanti Sumardiyono .

    2011-11-01

    Full Text Available Resistance mechanism of potato (Solanum tuberosum to golden cyst nematode (Globodera rostochiensis.  The research was conducted from June 2005 to May 2006 in Kepuhharjo, Cangkringan, Sleman, Yogyakarta. The aims of the research were to find the resistance status of 20 potato varieties, role of  chlorogenic acid and caffeic acid  in the resistance mechanism and histopathological differences between resistant and susceptible potato varieties to  G. rostochiensis. The results showed that two varieties were resistant to G. rostochiensis, i.e, Hertha and Manohara.  Thirteen varieties were moderately resistant, i.e; No.30, No.44, No. 5, No.19, Batang Hitam, Agria,  Desiree, Berolina, Atlantik, No.095, Cipanas, FLS and Colombus, and five varieties were susceptible, i.e; Kikondo, Granola, Erika, LBR, and Fries. The presence of chlorogenic acid and caffeic acid in Hertha (resistant variety and in Granola (susceptible variety were analized by TLC. In Hertha chlorogenic acid was detected at 4, 5, and 6 days after inoculation (DAI, whereas in Granola it was detected at 1 and 6 DAI. It was assumed that the presence of chlorogenic acid for 3 successively week in Hertha, caused it more resistant than Granola.  Cell lignification inhibited                       G. rostochiensis grow well inside the root tissue of Hertha, whereas in Granola only a few cell was lignified as indicated by less absorption of red colour (safranin in infected areas. Caffeic acid was not detected either in uninoculated or inoculated of both potato varieties.  It indicated that caffeic acid might not be naturally present in Hertha and Granola and nematode infection could not stimulate the production of this compound.

  14. Corrosion testing on crude oil tankers and other product carriers by means of acoustic emission (AE)

    Energy Technology Data Exchange (ETDEWEB)

    Lackner, Gerald [TUV Austria, Deutschstrasse 10, 1230 Wien (Austria); Tscheliesnig, Peter [TUV Austria, Deutschstrasse 10, 1230 Wien (Austria)

    2004-07-01

    In the last decades a lot of maritime disasters with crude oil tankers occurred (e.g. Exxon- Valdez, Erika, Prestige). Every accident led to extreme pollution with horrible consequences not only for the environment but also for the life of the inhabitants of the affected coasts. Although most of these accidents were caused by human errors, the material degradation of the ship hull due to corrosion played an important role. Acoustic emission (AE) is already used to detect and discriminate the stage of corrosion of structures located on land. A consortium consisting of experienced partners from the fields of ship building and classification as well as from AE testing and equipment manufacturing started to investigate the feasibility of this testing technique for its application on oil tankers. The aim of the research project funded by the European Commission is to develop an on-line corrosion monitoring technique based on a permanent installation of AE sensors as well as a spot testing technique during stops in harbors or at anchorages using mobile equipment. Since the project was started, a lot of lab tests as well as background measurements were done on different types of tankers up to a size of 35.000 dead weight tons (DWT). The gathered data were evaluated with a frequency domain based pattern recognition system and it was possible to distinguish the AE signals related to corrosion from those signals, which were emitted by the structure due to the harsh environment on sea (background noise). Together with the oncoming developments of the AE equipment and the improvement of the data base, this project will lead to an important breakthrough for the safe shipping of hazardous products like crude oil. (authors)

  15. Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.

    Science.gov (United States)

    Castrignanò, Silvia; D'Avino, Serena; Di Nardo, Giovanna; Catucci, Gianluca; Sadeghi, Sheila J; Gilardi, Gianfranco

    2018-01-01

    Chimerogenesis involving cytochromes P450 is a successful approach to generate catalytically self-sufficient enzymes. However, the connection between the different functional modules should allow a certain degree of flexibility in order to obtain functional and catalytically efficient proteins. We previously applied the molecular Lego approach to develop a chimeric P450 3A4 enzyme linked to the reductase domain of P450 BM3 (BMR). Three constructs were designed with the connecting loop containing no glycine, 3 glycine or 5 glycine residues and showed a different catalytic activity and coupling efficiency. Here we investigate how the linker affects the ability of P450 3A4 to bind substrates and inhibitors. We measure the electron transfer rates and the catalytic properties of the enzyme also in the presence of ketoconazole as inhibitor. The data show that the construct 3A4-5GLY-BMR with the longest loop better retains the binding ability and cooperativity for testosterone, compared to P450 3A4. In both 3A4-3GLY-BMR and 3A4-5GLY-BMR, the substrate induces an increase in the first electron transfer rate and a shorter lag phase related to a domain rearrangements, when compared to the construct without Gly. These data are consistent with docking results and secondary structure predictions showing a propensity to form helical structures in the loop of the 3A4-BMR and 3A4-3GLY-BMR. All three chimeras retain the ability to bind the inhibitor ketoconazole and show an IC 50 comparable with those reported for the wild type protein. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared Goldstone. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. See me! A Discussion on the Quality in Performing Arts for Children Based on a Performative Approach

    Directory of Open Access Journals (Sweden)

    Lisa Nagel

    2013-12-01

    Full Text Available In this article, the writer discusses and analyses what happens to our evaluation of quality in performing arts for children when we move from the notion of art as an object to art as an event. Erika Fischer-Lichte´s theory on the so-called performative turn in the arts and more specifically, the term the feedback loop, constitutes the article´s theoretical backdrop. Two audience-related episodes, respectively the dance performance BZz BZz-DADA dA bee by ICB Productions (3 - 6 year olds and the theatre performance Thought Lab by Cirka Teater (for 6 year olds and above, serve as starting points for the theoretical discussion. By adopting Siemke Böhnisch’s performative approach to performance analysis, focusing on the terms henvendthet (directed-ness, the actors´ and spectators´ mutual turning to the other and kontakt (connection in relations to the audience, the writer makes it possible to show a dissonance (and its reverse between the performers and the audience in the two respective performances. The term dissonance describes moments of unintended breaks in communication, moments of which the performers are most likely unaware. These moments however become apparent when the audience´s reactions are included in the analysis. The author concludes that by deferring to a performative perspective, we become almost obliged to consider the child audience as qualified judges of quality, as opposed to allowing ourselves to dismiss their interactions as either noise or enthusiasm. Such a perspective is important not only for how we see and evaluate performing arts for children, but also for how artists must think when producing performances for this audience.

  17. Protein engineering of CYP105s for their industrial uses.

    Science.gov (United States)

    Yasuda, Kaori; Sugimoto, Hiroshi; Hayashi, Keiko; Takita, Teisuke; Yasukawa, Kiyoshi; Ohta, Miho; Kamakura, Masaki; Ikushiro, Shinichi; Shiro, Yoshitsugu; Sakaki, Toshiyuki

    2018-01-01

    Cytochrome P450 enzymes belonging to the CYP105 family are predominantly found in bacteria belonging to the phylum Actinobacteria and the order Actinomycetales. In this review, we focused on the protein engineering of P450s belonging to the CYP105 family for industrial use. Two Arg substitutions to Ala of CYP105A1 enhanced its vitamin D 3 25- and 1α-hydroxylation activities by 400 and 100-fold, respectively. The coupling efficiency between product formation and NADPH oxidation was largely improved by the R84A mutation. The quintuple mutant Q87W/T115A/H132L/R194W/G294D of CYP105AB3 showed a 20-fold higher activity than the wild-type enzyme. Amino acids at positions 87 and 191 were located at the substrate entrance channel, and that at position 294 was located close to the heme group. Semi-rational engineering of CYP105A3 selected the best performing mutant, T85F/T119S/V194N/N363Y, for producing pravastatin. The T119S and N363Y mutations synergistically had remarkable effects on the interaction between CYP105A3 and putidaredoxin. Although wild-type CYP105AS1 hydroxylated compactin to 6-epi-pravastatin, the quintuple mutant I95T/Q127R/A180V/L236I/A265N converted almost all compactin to pravastatin. Five amino acid substitutions by two rounds of mutagenesis almost completely changed the stereo-selectivity of CYP105AS1. These results strongly suggest that the protein engineering of CYP105 enzymes greatly increase their industrial utility. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared Goldstone. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. "Comets, Origins, and Life:” Promoting Interdisciplinary Science in Secondary and Middle Schools in the Washington, DC and Saint Louis, MO Metro Areas

    Science.gov (United States)

    Bonev, Boncho; Gibb, E. L.; Brewer, G.; Novak, R.; Mandell, A. M.; Seaton, P.; Price, J.; Long, T.; Bahar, S.; Edwards, S. S.

    2010-10-01

    Developing a full-year program to support secondary and middle school science education is a key part of the "broader impact” component of NSF Grant AST- 0807939 (PI/Co-PI Bonev/Gibb). This program is realized at two stages: (1) a professional development course for teachers is offered during the summer; (2) during the subsequent academic year we collaborate with educators in lessons planning or curriculum development as demanded in their particular schools. We successfully offered the course “ Comets, Origins, and Life: Interdisciplinary Science in the Secondary Classroom ” (45 contact hours; 3 credits) in the summers of 2009 and 2010 at the Catholic University of America. This class demonstrates how a complex hypothesis - for the delivery of water and prebiotic organic matter to early Earth - is being tested by integrating astronomy, physics, chemistry, biology, and Earth and planetary science. Collaborations with participants from the 2009 class include curriculum development within the Earth Science program in Prince Georges county, MD and strengthening science in Washington DC public schools. Our next step is to offer our class in the Saint Louis, MO area. The main challenge in our work with educators is not to present them with "interesting information", but to fit what we offer within the very particular curriculum expectations of their school districts. These curriculum expectations often vary from district to district and sometimes from year to year. We gratefully acknowledge the support by the NSF, allowing to fully integrate our research area into education. We also gratefully acknowledge our collaborations with the Goddard Center for Astrobiology and the Howard B. Owens Science Center (both in MD) in developing our class curriculum. Educators interested in this program can contact Boncho Bonev (bonev@cua.edu; for the Washington DC and Baltimore, MD areas) and Erika Gibb (gibbe@umsl.edu; for the Saint Louis, MO area).

  19. Disseminare gesti pe(nsanti, archiviare danze di gravità. Spostamenti e passi nella ricerca

    Directory of Open Access Journals (Sweden)

    Annalisa Piccirillo

    2015-03-01

    Full Text Available This paper aims to share the movements or the steps that recently re-locate my research work. I talk about “re-location” to explain how, after my PhD studies, are still central some specific “directions” of analysis: 1 the “feminine” and the incalculable creativity displayed by women’s choreo-graphy; 2 the “archive”, a space of embodied deposition and survival that keeps challenging the claimed ephemerality of dance. In my current research process, I re-locate my thinking/dancing body towards new questions, gestures and events to be observed. I rely on the methodological tools provided by cultural and postcolonial studies; I position myself at the crossroad of Dance Studies and deconstruction; I move across the fleeting borders of the aesthetics of dance, video-dance and digital performance, in order to trace and re-trace, as I were performing an archival exercise, the seeds – the memory-gestures – inscribed and disseminated by some examples of female writing. I consult a Matriarchive: an imagined space of archivization where women-choreographers are the “archons”: they “commence” and “command” their body writing; they use their insurgent body-weight to affirm their agency; they re-inscribe the contemporary scene with new embedded body languages. I investigate, more specifically, the kinetic quality of “gravity”: a corporeal technique and poetics which has been embodied, denied or rejected; a choreographic law which has been historically archived and displaced on the screen (Maya Deren The Very Eye of Night, 1958; it has been re-located on the liquid architectures of the digital/urban space (Erika Janunger, Wheightless, 2006; to be disseminated, beyond and elsewhere, on the new archival space provided by video-performance installation (Nisrine Boukhari, The veil, 2006.

  20. Health care resource utilization before and after natalizumab initiation among patients with multiple sclerosis in Germany

    Directory of Open Access Journals (Sweden)

    Watson C

    2017-02-01

    Full Text Available Crystal Watson,1 Christine Prosser,2 Sebastian Braun,2 Pamela B Landsman-Blumberg,3 Erika Gleissner,4 Sarah Naoshy1 1Health Economics and Outcomes Research, Global Market Access, Biogen, Cambridge, MA, USA; 2Real World Evidence, Xcenda GmbH, Hanover, Germany; 3Applied Data Analytics, Xcenda LLC, Palm Harbor, FL, USA; 4Market Access, Biogen, Ismaning, Germany Background: Multiple sclerosis (MS, a progressive neurodegenerative disease, greatly impacts the quality of life and economic status of people affected by this disease. In Germany, the total annual cost of MS is estimated at €40,000 per person with MS. Natalizumab has shown to slow MS disease progression, reduce relapses, and improve the quality of life of people with MS.Objective: To evaluate MS-related and all-cause health care resource utilization and costs among German MS patients during the 12 months before and after initiation of natalizumab in a real-world setting.Methods: The current analysis was conducted using the Health Risk Institute research database. Identified patients were aged ≥18 years with ≥1 diagnosis of MS and had initiated natalizumab therapy (index, with 12-month pre– and post–index-period data. Patients were stratified by prior disease-modifying therapy (DMT usage or no DMT usage in the pre-index period. Outcome measures included corticosteroid use and number of sick/disability days, inpatient stays, and outpatient visits. Health care costs were calculated separately for pre- and post-index periods on a per-patient basis and adjusted for inflation.Results: In a final sample of 193 natalizumab-treated patients, per-patient MS-related corticosteroid use was reduced by 62.3%, MS-related sick days by 27.6%, and inpatient costs by 78.3% from the pre- to post-index period. Furthermore, the proportion of patients with MS-related hospitalizations decreased from 49.7% to 14.0% (P<0.001; this reduction was seen for patients with and without prior DMT use

  1. Nicoboxil/nonivamide cream effectively and safely reduces acute nonspecific low back pain – a randomized, placebo-controlled trial

    Directory of Open Access Journals (Sweden)

    Blahova Z

    2016-12-01

    Full Text Available Zuzana Blahova,1 Janina Claudia Holm,1 Thomas Weiser,2 Erika Richter,2 Matthias Trampisch,2 Elena Akarachkova3 1Boehringer Ingelheim RCV GmbH & Co KG, Vienna, Austria; 2Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim am Rhein, Germany; 3I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation Background/objective: Low back pain affects many patients and has a high socioeconomic impact. Topical capsaicinoids have been used for decades to treat musculoskeletal pain. This study investigated the effects of the fixed dose combination (FDC of nonivamide (a capsaicinoid and nicoboxil (a nicotinic acid ester cream in the treatment of acute nonspecific low back pain.Materials and methods: This phase III randomized, double-blind, placebo-controlled, multinational, multi-center trial investigated efficacy, safety, and tolerability of topical nicoboxil 1.08%/nonivamide 0.17% (Finalgon® cream in treatment of acute nonspecific low back pain with the endpoints: pain intensity (PI difference between pre-dose baseline and 8 hours after first application and the end of treatment, mobility score, and efficacy score.Results: Patients (n=138, 21–65 years of age, were treated for up to 4 days with FDC or placebo cream. Mean baseline PI was 6.8 on a 0–10 point numerical rating scale. After 8 hours, pain was more reduced with the FDC than with placebo (adjusted means: 2.824 vs. 0.975 points; p<0.0001. On the last treatment day, mean pain reduction by the FDC was stronger than with placebo (adjusted means: 5.132 vs. 2.174 points; p<0.0001. Mobility on Day 1 was in favor of the FDC when compared to placebo (odds ratio [95% confidence interval {CI}]: 7.200 [3.609, 14.363], p<0.0001. At the end of treatment, patients treated with the FDC rated efficacy significantly higher than placebo (odds ratio [95% CI]: 11.370 [5.342, 24.199], p<0.0001. Both treatments were tolerated well. No serious adverse events were reported.Conclusion: Nicoboxil

  2. Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus

    Directory of Open Access Journals (Sweden)

    Hashizume E

    2013-02-01

    Full Text Available Erika Hashizume,1 Tetsuo Nakano,2 Ayako Kamimura,1 Koji Morishita31Healthcare Products Development Center, Kyowa Hakko Bio, Tsukuba, Ibaraki, 2Technical Research Laboratories, Kyowa Hakko Bio, Hofu, Yamaguchi, 3Technology Development and Research Department, Kyowa Hakko Bio, Tokyo, JapanPurpose: N-acetyl-l-hydroxyproline (AHYP is an acetylated form of l-hydroxyproline that is used to treat skin ulcers and porphyria cutanea tarda. Its other biological and physiological effects on the skin have not been elucidated. We investigated the effects of AHYP on the skin-barrier function, focusing on ceramide synthesis and the effects of topical AHYP on atopic dermatitis.Materials and methods: AHYP was applied to a three-dimensional cultured skin model. Ceramides were quantified by high-performance thin-layer chromatography. Serine palmitoyltransferase (SPT is the rate-limiting enzyme in de novo ceramide synthesis, and the mRNA of its long-chain base subunit 1 (SPTLC1 was evaluated by quantitative reverse-transcription polymerase chain reaction. A clinical trial in the form of an intraindividual, comparative, double-blind, randomized, vehicle-controlled test involving 15 female subjects suffering from slight atopic dermatitis was performed. Subjects applied 1% (w/w AHYP cream to one forearm and a control cream to the other forearm twice daily for 4 weeks. Skin condition was evaluated by measuring transepidermal water loss (TEWL. Dermatological observations were made by a dermatologist, and subjects evaluated their own pruritus intensity before beginning treatment and 4 weeks after the start of treatment.Results: SPTLC1 expression and ceramide synthesis were significantly increased in an AHYP-treated skin model (P < 0.05. In the clinical trial, no adverse effects were observed in any subjects. TEWL was increased in the control-treated region of the forearm (P < 0.05 after 4 weeks' application, whereas there was no change in the AHYP-treated region of the

  3. The ultrasound-guided retrolaminar block: volume-dependent injectate distribution

    Directory of Open Access Journals (Sweden)

    Damjanovska M

    2018-02-01

    Full Text Available Marija Damjanovska,1 Tatjana Stopar Pintaric,1,2 Erika Cvetko,2 Kamen Vlassakov3 1Clinical Department of Anesthesiology and Intensive Therapy, University Medical Centre Ljubljana, Ljubljana, Slovenia; 2Institute of Anatomy, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 3Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA Purpose: The ultrasound-guided retrolaminar block is one of the newer and simpler alternatives to the traditional, often technically challenging, paravertebral (PV block. Its feasibility, safety, and efficacy have already been clinically demonstrated in patients with multiple rib fractures using higher volumes of local anesthetic, when compared with the traditional approach. The primary aim of this observational anatomical study was to assess the spread of local anesthetic from the retrolaminar injection point to the PV space and its volume dependence. Second, we assessed the incidence of epidural and contralateral PV spread in the both groups.Methods: Ten fresh porcine cadavers were randomized into 2 groups (n=5 each to receive ultrasound-guided retrolaminar injections at Th4-Th5 level with either 10 mL (low-volume group or 30 mL (high-volume group of 2% lidocaine and methylene blue mixture. After the procedure, the cadavers were dissected and frozen. Cross-section cuts (~1 cm thick were performed to evaluate the injectate spread.Results: In the high-volume group, injectate spread from the retrolaminar to the PV space was observed in all specimens (5 out of 5; 100%, while in the low-volume group, no apparent spread to the PV space was found (0 out of 5; 0%. No epidural or contralateral PV spread was observed in any of the specimens.Conclusion: Following ultrasound-guided retrolaminar injections in fresh porcine cadavers, injectate spread from the retrolaminar tissue plane to the PV space is strongly volume dependent

  4. A systematic review and meta-analysis on the use of prophylactic topical antibiotics for the prevention of uncomplicated wound infections

    Directory of Open Access Journals (Sweden)

    Tong Q

    2018-03-01

    Full Text Available Qiao-Jing Tong,1 Kimberly DP Hammer,2,3 Erika M Johnson,4 Milagros Zegarra,2,3 Michihiko Goto,5,6 Tze Shien Lo3,7 1Department of Infection Control, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; 2Research Service, Fargo VA Health Care System; 3Department of Internal Medicine, University of North Dakota, School of Medicine and Health Sciences, Fargo, ND, USA; 4Library Resources, University of North Dakota, School of Medicine and Health Sciences, Fargo, ND, USA; 5Center for Comprehensive Access & Delivery Research & Evaluation (CADRE, Iowa City VA Health Care System, West Iowa City, IA, USA; 6Department of Internal Medicine, University of Iowa, Carver College of Medicine, Iowa City, IA, USA; 7Infectious Disease Service, Fargo VA Health Care System, Fargo, ND, USA Background: The prescription of topical antibiotics for the prevention of infections in uncomplicated wounds is common. However, the efficacy is not well reported. Therefore, the objective of the study was to conduct a systematic review and meta-analysis of the available evidence on prevention of uncomplicated wound infections by prophylactic topical antibiotics. Materials and methods: The search included Pubmed, Google Scholar, SCOPUS, Embase, Cochrane, ClinicalTrials.gov, International Clinical Trials Registry Platform, National Technical Information Service, and the National Guidelines Clearinghouse. Results: We identified eight randomized controlled trials and four quasi-randomized trials that met the criteria for the systematic review. Of these trials, 11 studies were pooled for meta-analysis to compare the effects of topical antibiotics versus placebo and 4 studies were pooled for comparison of effects of topical antibiotics versus topical antiseptics on uncomplicated wounds. Fewer wound infections occurred in the topical antibiotic arms compared to placebo (pooled risk ratio: 0.57 [95% CI: 0.37 to 0.86]; p=0.01 and pooled risk

  5. Graphene oxide scaffold accelerates cellular proliferative response and alveolar bone healing of tooth extraction socket

    Directory of Open Access Journals (Sweden)

    Nishida E

    2016-05-01

    Full Text Available Erika Nishida,1 Hirofumi Miyaji,1 Akihito Kato,1 Hiroko Takita,2 Toshihiko Iwanaga,3 Takehito Momose,1 Kosuke Ogawa,1 Shusuke Murakami,1 Tsutomu Sugaya,1 Masamitsu Kawanami11Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan; 2Support Section for Education and Research, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan; 3Laboratory of Histology and Cytology, Hokkaido University Graduate School of Medicine, Sapporo, JapanAbstract: Graphene oxide (GO consisting of a carbon monolayer has been widely investigated for tissue engineering platforms because of its unique properties. For this study, we fabricated a GO-applied scaffold and assessed the cellular and tissue behaviors in the scaffold. A preclinical test was conducted to ascertain whether the GO scaffold promoted bone induction in dog tooth extraction sockets. For this study, GO scaffolds were prepared by coating the surface of a collagen sponge scaffold with 0.1 and 1 µg/mL GO dispersion. Scaffolds were characterized using scanning electron microscopy (SEM, physical testing, cell seeding, and rat subcutaneous implant testing. Then a GO scaffold was implanted into a dog tooth extraction socket. Histological observations were made at 2 weeks postsurgery. SEM observations show that GO attached to the surface of collagen scaffold struts. The GO scaffold exhibited an interconnected structure resembling that of control subjects. GO application improved the physical strength, enzyme resistance, and adsorption of calcium and proteins. Cytocompatibility tests showed that GO application significantly increased osteoblastic MC3T3-E1 cell proliferation. In addition, an assessment of rat subcutaneous tissue response revealed that implantation of 1 µg/mL GO scaffold stimulated cellular ingrowth behavior, suggesting that the GO scaffold exhibited good biocompatibility. The tissue ingrowth area and DNA contents of 1

  6. Studies of water-in-oil emulsions : testing of emulsion formation in OHMSETT

    International Nuclear Information System (INIS)

    Fingas, M.; Fieldhouse, B.

    2001-01-01

    of water-in-oil states. The confirmation of one emulsion formed at sea from the ERIKA spill, showed some evidence that this is also analogous to conditions at sea. 4 refs., 7 tabs., 4 figs

  7. Diagnostic accuracy of nodular gastritis for H. pylori infection

    Directory of Open Access Journals (Sweden)

    Romero-Flores JL

    2016-12-01

    Full Text Available Juan L Romero-Flores,1 Justo A Fernandez-Rivero,1 Erika Marroquín-Fabian,1 Félix I Téllez-Ávila,2 Beatriz A Sánchez-Jiménez,1 Eva Juárez-Hernández,3 Misael Uribe,1 Norberto C Chávez-Tapia1,3 1Obesity and Digestive Diseases Unit, Medica Sur Clinic & Foundation, 2Department of Gastrointestinal Endoscopy, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, 3Translational Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico Background: The term nodular is not included in the Sydney classification and there is no widely accepted histopathological definition. It has been proposed that the presence of antral nodularity could predict Helicobacter pylori (H. pylori infection. The aim of this study was to determine the diagnostic accuracy of nodular gastritis (NG for H. pylori infection after a rigorous standardization process, and to describe the associated histopathological characteristics. Materials and methods: Endoscopic images of patients submitted to endoscopy with biopsy sampling were included. Endoscopic images were distributed among six endoscopists. The analysis was performed sequentially in three rounds: the first round assessed the interobserver variability, the second evaluated the intraobserver variability, and the third calculated the interobserver variability after training. A correlation analysis between endoscopic and histopathological findings was performed. Results: A total of 917 studies were included. In the first analysis of interobserver variability, a poor kappa value (0.078 was obtained. The second evaluation yielded good intraobserver variability, with kappa values of 0.62–0.86. The evaluation of interobserver variability after training revealed an improvement in the kappa value of 0.42. A correlation was found between endoscopic images and histopathological reports. Conclusion: There was a strong correlation between NG and H. pylori, but only after rigorous evaluation. The use of

  8. Predictors of communication preferences in patients with chronic low back pain

    Directory of Open Access Journals (Sweden)

    Farin E

    2013-10-01

    Full Text Available Erik Farin, Lukas Gramm, Erika SchmidtUniversity Freiburg, Medical Center, Department of Quality Management and Social Medicine, Freiburg, GermanyBackground: The objective of this exploratory study was to identify patient-related predictors of communication preferences in patients with chronic low back pain for various dimensions of patient-physician communication (patient participation and orientation, effective and open communication, emotionally supportive communication, communication about personal circumstances.Methods: Eleven rehabilitation centers from various parts of Germany participated in collection of data between 2009 and 2011. A total of 701 patients with chronic low back pain were surveyed at the start of rehabilitation. The patient questionnaire captured communication preferences, pain impact, pain intensity, and psychologic variables (fear avoidance beliefs, illness coherence, control beliefs, communication self-efficacy, and personality characteristics. The rehabilitation physicians filled out a documentation sheet containing information on diagnosis, inability to work, duration of the illness, and comorbidity at the beginning and end of rehabilitation. Hierarchical regression analyses were performed.Results: On average, effective, open, and patient-centered communication was very important for patients with back pain, emotionally supportive communication was important, and communication about personal circumstances was somewhat important. The variance in communication preferences explained by the predictors studied here was 8%–19%. Older patients showed a lower preference for patient-centered and open communication, but a higher preference for communication about personal circumstances. Patients with psychologic risk factors (eg, fear avoidance beliefs, extroverted patients, and patients with high self-efficacy in patient-physician interaction generally had higher expectations of the physician's communicative behavior

  9. Patient-Facing Mobile Apps to Treat High-Need, High-Cost Populations: A Scoping Review.

    Science.gov (United States)

    Singh, Karandeep; Drouin, Kaitlin; Newmark, Lisa P; Filkins, Malina; Silvers, Elizabeth; Bain, Paul A; Zulman, Donna M; Lee, Jae-Ho; Rozenblum, Ronen; Pabo, Erika; Landman, Adam; Klinger, Elissa V; Bates, David W

    2016-12-19

    the data. This is one limitation of our study. With respect to the 40 articles (22.9%, 40/175) that were assigned to 2 reviewers (of which 3 articles were excluded), inter-rater agreement was significant on the majority of items (17 of 30) but fair-to-moderate on others. ©Karandeep Singh, Kaitlin Drouin, Lisa P Newmark, Malina Filkins, Elizabeth Silvers, Paul A Bain, Donna M Zulman, Jae-Ho Lee, Ronen Rozenblum, Erika Pabo, Adam Landman, Elissa V Klinger, David W Bates. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 19.12.2016.

  10. Functionalized poly(3-hydroxybutyric acid) bodies as new in vitro biocatalysts.

    Science.gov (United States)

    Stenger, Benjamin; Gerber, Adrian; Bernhardt, Rita; Hannemann, Frank

    2018-01-01

    Cytochromes P450 play a key role in the drug and steroid metabolism in the human body. This leads to a high interest in this class of proteins. Mammalian cytochromes P450 are rather delicate. Due to their localization in the mitochondrial or microsomal membrane, they tend to aggregate during expression and purification and to convert to an inactive form so that they have to be purified and stored in complex buffers. The complex buffers and low storage temperatures, however, limit the feasibility of fast, automated screening of the corresponding cytochrome P450-effector interactions, which are necessary to study substrate-protein and inhibitor-protein interactions. Here, we present the production and isolation of functionalized poly(3-hydroxybutyrate) granules (PHB bodies) from Bacillus megaterium MS941 strain. In contrast to the expression in Escherichia coli, where mammalian cytochromes P450 are associated to the cell membrane, when CYP11A1 is heterologously expressed in Bacillus megaterium, it is located on the PHB bodies. The surface of these particles provides a matrix for immobilization and stabilization of the CYP11A1 during the storage of the protein and substrate conversion. It was demonstrated that the PHB polymer basis is inert concerning the performed conversion. Immobilization of the CYP11A1 onto the PHB bodies allows freeze-drying of the complex without significant decrease of the CYP11A1 activity. This is the first lyophilization of a mammalian cytochrome P450, which allows storage over more than 18days at 4°C instead of storage at -80°C. In addition, we were able to immobilize the cytochrome P450 on the PHB bodies in vitro. In this case the expression of the protein is separated from the production of the immobilization matrix, which widens the application of this method. This article is part of a Special Issue entitled: Cytochrome P450 biodiversity and biotechnology, edited by Erika Plettner, Gianfranco Gilardi, Luet Wong, Vlada Urlacher, Jared

  11. Risk-benefit considerations in the treatment of relapsing-remitting multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Lugaresi A

    2013-06-01

    Full Text Available Alessandra Lugaresi,1 Maria di Ioia,1 Daniela Travaglini,1 Erika Pietrolongo,1 Eugenio Pucci,2 Marco Onofrj11Department of Neuroscience and Imaging, University “G d’Annunzio”, Chieti, 2Operative Unit Neurologia ASUR Marche Area Vasta 3, Macerata, ItalyAbstract: Multiple sclerosis (MS is a chronic demyelinating disease of the central nervous system and mainly affects young adults. Its natural history has changed in recent years with the advent of disease-modifying drugs, which have been available since the early 1990s. The increasing number of first-line and second-line treatment options, together with the variable course of the disease and patient lifestyles and expectations, makes the therapeutic decision a real challenge. The aim of this review is to give a comprehensive overview of the main present and some future drugs for relapsing-remitting MS, including risk-benefit considerations, to enable readers to draw their own conclusions regarding the risk-benefit assessment of personalized treatment strategies, taking into account not only treatment-related but also disease-related risks. We performed a Medline literature search to identify studies on the treatment of MS with risk stratification and risk-benefit considerations. We focused our attention on studies of disease-modifying, immunomodulating, and immunosuppressive drugs, including monoclonal antibodies. Here we offer personal considerations, stemming from long-term experience in the treatment of MS and thorough discussions with other neurologists closely involved in the care of patients with the disease. MS specialists need to know not only the specific risks and benefits of single drugs, but also about drug interactions, either in simultaneous or serial combination therapy, and patient comorbidities, preferences, and fears. This has to be put into perspective, considering also the risks of untreated disease in patients with different clinical and radiological characteristics

  12. Investigating the Perceptions of Care Coordinators on Using Behavior Theory-Based Mobile Health Technology With Medicaid Populations: A Grounded Theory Study.

    Science.gov (United States)

    Sigler, Brittany Erika

    2017-03-21

    behaviors, as well as an improved client-care manager relationship. Messaging platform features tied to health behavior theory appear to be effective in improving patient engagement. Two-way communication (supportive accountability), trusted relationships (supportive accountability, SCT), personalized messages (TTM), and patient input (TTM, SCT, MI) appeared as the most relevant components in achieving desired outcomes. Additionally, reminder messages were noted as especially useful in making Medicaid patients accountable and in turn engaging them in their health and health care. These findings convey suggested elements for inclusion in other mHealth interventions aiming to improve patient engagement in Medicaid populations. ©Brittany Erika Sigler. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 21.03.2017.

  13. Pharmacokinetic/pharmacodynamic analysis of teicoplanin in patients with MRSA infections

    Directory of Open Access Journals (Sweden)

    Matsumoto K

    2016-03-01

    Full Text Available Kazuaki Matsumoto,1 Erika Watanabe,1 Naoko Kanazawa,1 Tomohide Fukamizu,1 Akari Shigemi,1 Yuta Yokoyama,1,2 Kazuro Ikawa,2 Norifumi Morikawa,2 Yasuo Takeda1 1Department of Clinical Pharmacy and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, 2Department of Clinical Pharmacotherapy, Hiroshima University, Hiroshima, Japan Background: Teicoplanin is a glycopeptide antibiotic that has been used to treat serious, invasive infections caused by Gram-positive bacteria. The area under the drug concentration–time curve (AUC/minimum inhibitory concentration (MIC was identified as a pharmacokinetic–pharmacodynamic (PK–PD parameter of glycopeptide antibiotics that correlated with bacteriological responses and clinical outcomes. Although optimized dosing regimens based on PK–PD are needed, a PK–PD analysis of teicoplanin against methicillin-resistant Staphylococcus aureus (MRSA infections has not yet been performed. Thus, this study examined patients with MRSA infections, who were administered with teicoplanin in order to determine the target AUC/MIC ratio. Methods: This study retrospectively assessed data obtained as part of our routine therapeutic drug monitoring (TDM of teicoplanin therapy in 46 patients with MRSA infections at Kagoshima University Hospital. Serum concentrations of teicoplanin were determined using a fluorescence polarization immunoassay system and used for a Bayesian PK estimation to estimate AUC for 24 hours (AUC24. The MIC value for teicoplanin was determined using a standardized agar dilution method. The effects of teicoplanin were evaluated in terms of bacteriological responses by a quantitative assessment. Results: The estimated AUC24/MIC ratios with and without bacteriological responses were 926.6±425.2 µg·h/mL (n=34 and 642.2±193.9 µg·h/mL, respectively (n=12; P<0.05. On the basis of a logistic regression analysis, AUC24/MIC ratios of 500 µg·h/mL, 700 µg·h/mL, and

  14. Hydrogenation of benzaldehyde via electrocatalysis and thermal catalysis on carbon-supported metals

    Energy Technology Data Exchange (ETDEWEB)

    Song, Yang; Sanyal, Udishnu; Pangotra, Dhananjai; Holladay, Jamelyn D.; Camaioni, Donald M.; Gutierrez-Tinoco, Oliver Y.; Lercher, Johannes A.

    2018-03-01

    Abstract Selective reduction of benzaldehyde to benzyl alcohol on C-supported Pt, Rh, Pd, and Ni in aqueous phase was conducted using either directly H2 (thermal catalytic hydrogenation, TCH) or in situ electrocatalytically generated hydrogen (electrocatalytic hydrogenation, ECH). In TCH, the intrinsic activity of the metals at room temperature and 1 bar H2 increased in the sequence Rh/C < Pt/C < Pd/C, while Ni/C is inactive at these conditions due to surface oxidation in the absence of cathodic potential. The reaction follows a Langmuir-Hinshelwood mechanism with the second hydrogen addition to the adsorbed hydrocarbon being the rate-determining step. All tested metals were active in ECH of benzaldehyde, although hydrogenation competes with the hydrogen evolution reaction (HER). The minimum cathodic potentials to obtain appreciable ECH rates were identical to the onset potentials of HER. Above this onset, the relative rates of H reacting to H2 and H addition to the hydrocarbon determines the selectivity to ECH and TCH. Accordingly, the selectivity of the metals towards ECH increases in the order Ni/C < Pt/C < Rh/C < Pd/C. Pd/C shows exceptionally high ECH selectivity due to its surprisingly low HER reactivity under the reaction conditions. Acknowledgements The authors would like to thank the groups of Hubert A. Gasteiger at the Technische Universität München of Jorge Gascon at the Delft University of Technology for advice and valuable discussions. The authors are grateful to Nirala Singh, Erika Ember, Gary Haller, and Philipp Rheinländer for fruitful discussions. We are also grateful to Marianne Hanzlik for TEM measurements and to Xaver Hecht and Martin Neukamm for technical support. Y.S. would like to thank the Chinese Scholarship Council for the financial support. The research described in this paper is part of the Chemical Transformation Initiative at Pacific Northwest National Laboratory (PNNL), conducted under the Laboratory Directed Research and

  15. Cost of rheumatoid arthritis in a selected population from Argentina in the prebiologic therapy era

    Directory of Open Access Journals (Sweden)

    Catay E

    2012-08-01

    Full Text Available Erika Catay,1 Cecilia Castel del Cid,1 Lorena Narváez,1 Edson J Velozo,1 Javier E Rosa,1,2 Luis J Catoggio,1,2 Enrique R Soriano1,21Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, 2University Institute Hospital Italiano de Buenos Aires, School of Medicine, PM Catoggio Foundation, Buenos Aires, ArgentinaBackground: The present study aimed to estimate the cost of rheumatoid arthritis and its components in a university hospital-based health management organization in Argentina, during the prebiologic era.Methods: A one-year (2002 observational prevalence, cost-of illness study of patients with rheumatoid arthritis from the societal perspective was performed in a hospital-based health management organization population. Direct medical costs were obtained using administrative databases. Direct nonmedical and indirect costs were obtained from a semistructured questionnaire. Indirect costs included work absenteeism, permanent work disability, and housework lost for housewives, using the human capital approach. Costs are expressed in 2002 US dollars per patient per year.Results: A total of 165 patients (84% females, of mean age 61 ± 15 years and with a mean disease duration of 8.5 ± 8.3 years were included. Mean total direct medical costs were US$1862 (95% confidence interval [CI] 828–2899. Mean direct nonmedical costs were US$222 (95% CI 149–294. Mean indirect costs were US$1008 (95% CI 606–1412. The annual mean total cost was US$3093 without biologics. Hospitalizations represented 73% of total direct medical costs while drugs and outpatient procedures represented 16% and 8% of total direct medical costs, respectively. Sixty percent of the total costs were related to direct medical costs, while indirect costs represented 33% of total costs.Conclusion: In our population, annual mean total costs in the prebiologic therapy era were mainly driven by direct medical costs. Even without the use of biologic agents

  16. Unexpected effects of peripherally administered kynurenic acid on cortical spreading depression and related blood–brain barrier permeability

    Directory of Open Access Journals (Sweden)

    Oláh G

    2013-09-01

    Full Text Available Gáspár Oláh,1 Judit Herédi,1 Ákos Menyhárt,1 Zsolt Czinege,2 Dávid Nagy,1 János Fuzik,1 Kitti Kocsis,1 Levente Knapp,1 Erika Krucsó,1 Levente Gellért,1 Zsolt Kis,1 Tamás Farkas,1 Ferenc Fülöp,3 Árpád Párdutz,4 János Tajti,4 László Vécsei,4 József Toldi1 1Department of Physiology, Anatomy and Neuroscience, 2Department of Software Engineering, 3Institute of Pharmaceutical Chemistry and MTA-SZTE Research Group for Stereochemistry, 4Department of Neurology and MTA-SZTE Neuroscience Research Group, University of Szeged, Szeged, Hungary Abstract: Cortical spreading depression (CSD involves a slowly-propagating depolarization wave in the cortex, which can appear in numerous pathophysiological conditions, such as migraine with aura, stroke, and traumatic brain injury. Neurons and glial cells are also depolarized transiently during the phenomena. CSD is followed by a massive increase in glutamate release and by changes in the brain microcirculation. The aim of this study was to investigate the effects of two N-methyl-D-aspartate receptor antagonists, endogenous kynurenic acid (KYNA and dizocilpine, on CSD and the related blood–brain barrier (BBB permeability in rats. In intact animals, KYNA hardly crosses the BBB but has some positive features as compared with its precursor L-Kynurenine, which is frequently used in animal studies (KYNA cannot be metabolized to excitotoxic agents such as 3-hydroxy-L-kynurenine and quinolinic acid. We therefore investigated the possible effects of peripherally administered KYNA. Repetitive CSD waves were elicited by the application of 1 M KCl solution to the cortex. Direct current-electrocorticograms were measured for 1 hour. Four parameters of the waves were compared. Evans blue dye and fluorescent microscopy were used to study the possible changes in the permeability of the BBB. The results demonstrated that N-methyl-D-aspartate receptor antagonists can reduce the number of CSD waves and decrease

  17. A revision of the genus Planinasus Cresson (Diptera, Periscelididae

    Directory of Open Access Journals (Sweden)

    Wayne Mathis

    2012-10-01

    Full Text Available The genus Planinasus Cresson is revised and includes 18 extant and one fossil species. We clarify the status of the three previously described species and describe 15 new species as follows (type locality in parenthesis: P. aenigmaticus (Colombia. Bogota: Bogota (04°35.8`N, 74°08.8`W, P. neotropicus (Panama. Canal Zone: Barro Colorado Island (09°09.1`N, 79°50.8`W, P. kotrbae (Ecuador. Orellana: Rio Tiputini Biodiversity Station (0°38.2`S, 76°08.9`W, P. miradorus (Brazil. Maranhão: Parque Estadual Mirador, Base da Geraldina (06°22.2`S, 44°21.8`W, P. tobagoensis (Trinidad and Tobago. Tobago. St. John: Parlatuvier (11°17.9`N, 60°39`W, P. xanthops (Ecuador. Orellana: Rio Tiputini Biodiversity Station (0°38.2`S, 76°8.9`W, P. argentifacies (Peru. Madre de Dios: Río Manu, Pakitza (11°56.6`S, 71°16.9`W; 250 m, P. insulanus (Dominican Republic. La Vega: near Jarabacoa, Salto Guasara (19°04.4`N, 70°42.1`W, 680 m, P. nigritarsus (Guyana. Conservation of Ecological Interactions and Biotic Associations (CEIBA; ca. 40 km S Georgetown; 06°29.9`N, 58°13.1`W, P. atriclypeus (Brazil. Rio de Janeiro: Rio de Janeiro, Floresta da Tijuca (22°57.6`S, 43°16.4`W, P. atrifrons (Bolivia. Santa Cruz: Ichilo, Buena Vista (4-6 km SSE; Hotel Flora y Fauna; 17°29.95`S, 63°33.15`W; 4-500 m, P. flavicoxalis (West Indies. Dominica. St. David: 1.6 km N of junction of roads to Rosalie and Castle Bruce (15°23.8`N, 61°18.6`W, P. mcalpineorum (Mexico. Chiapas: Cacahoatan (7 km N; 15°04.1`N, 92°07.4`W, P. nigrifacies (Brazil. São Paulo: Mogi das Cruzes, Serra do Itapeti (23°31.5`S, 46°11.2`W, P. obscuripennis (Peru. Madre de Dios: Río Manu, Erika (near Salvación; 12°50.7`S, 71°23.3`W; 550 m. In addition to external characters, we also describe and illustrate structures of the male terminalia and for P. kotrbae sp. n., the internal female reproductive organs. Detailed locality data and distribution maps for all species are provided. For perspective and

  18. A revision of the genus Planinasus Cresson (Diptera, Periscelididae).

    Science.gov (United States)

    Mathis, Wayne N; Rung, Alessandra; Kotrba, Marion

    2012-01-01

    The genus Planinasus Cresson is revised and includes 18 extant and one fossil species. We clarify the status of the three previously described species and describe 15 new species as follows (type locality in parenthesis): Planinasus aenigmaticus (Colombia. Bogota: Bogota (04°35.8'N, 74°08.8'W)), Planinasus neotropicus (Panama. Canal Zone: Barro Colorado Island (09°09.1'N, 79°50.8'W)), Planinasus kotrbae (Ecuador. Orellana: Rio Tiputini Biodiversity Station (0°38.2'S, 76°08.9'W)), Planinasus miradorus (Brazil. Maranhão: Parque Estadual Mirador, Base da Geraldina (06°22.2'S, 44°21.8'W)), Planinasus tobagoensis (Trinidad and Tobago. Tobago. St. John: Parlatuvier (11°17.9'N, 60°39'W)), Planinasus xanthops (Ecuador. Orellana: Rio Tiputini Biodiversity Station (0°38.2'S, 76°8.9'W)), Planinasus argentifacies (Peru. Madre de Dios: Río Manu, Pakitza (11°56.6'S, 71°16.9'W; 250 m)), Planinasus insulanus (Dominican Republic. La Vega: near Jarabacoa, Salto Guasara (19°04.4'N, 70°42.1'W, 680 m)), Planinasus nigritarsus (Guyana. Conservation of Ecological Interactions and Biotic Associations (CEIBA; ca. 40 km S Georgetown; 06°29.9'N, 58°13.1'W)), Planinasus atriclypeus (Brazil. Rio de Janeiro: Rio de Janeiro, Floresta da Tijuca (22°57.6'S, 43°16.4'W)), Planinasus atrifrons (Bolivia. Santa Cruz: Ichilo, Buena Vista (4-6 km SSE; Hotel Flora y Fauna; 17°29.95'S, 63°33.15'W; 4-500 m)), P. flavicoxalis (West Indies. Dominica. St. David: 1.6 km N of junction of roads to Rosalie and Castle Bruce (15°23.8'N, 61°18.6'W)), Planinasus mcalpineorum (Mexico. Chiapas: Cacahoatan (7 km N; 15°04.1'N, 92°07.4'W)), Planinasus nigrifacies (Brazil. São Paulo: Mogi das Cruzes, Serra do Itapeti (23°31.5'S, 46°11.2'W)), Planinasus obscuripennis (Peru. Madre de Dios: Río Manu, Erika (near Salvación; 12°50.7'S, 71°23.3'W; 550 m)). In addition to external characters, we also describe and illustrate structures of the male terminalia and for Planinasus kotrbaesp. n., the

  19. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2010-12-01

    úa, by Allen Wells (reviewed by Michael R. Hall Downtown Ladies: Informal Commercial Importers, a Haitian Anthropologist, and Self-Making in Jamaica, by Gina A. Ulysse (reviewed by Jean Besson Une ethnologue à Port-au-Prince: Question de couleur et luttes pour le classement socio-racial dans la capitale haïtienne, by Natacha Giafferi-Dombre (reviewed by Catherine Benoît Haitian Vodou: Spirit, Myth, and Reality, edited by Patrick Bellegarde-Smith & Claudine Michel (reviewed by Susan Kwosek Cuba: Religion, Social Capital, and Development, by Adrian H. Hearn (reviewed by Nadine Fernandez "Mek Some Noise": Gospel Music and the Ethics of Style in Trinidad, by Timothy Rommen (reviewed by Daniel A. Segal Routes and Roots: Navigating Caribbean and Pacific Island Literatures, by Elizabeth M. DeLoughrey (reviewed by Anthony Carrigan Claude McKay, Code Name Sasha: Queer Black Marxism and the Harlem Renaissance, by Gary Edward Holcomb (reviewed by Brent Hayes Edwards The Sense of Community in French Caribbean Fiction, by Celia Britton (reviewed by J. Michael Dash Imaging the Chinese in Cuban Literature and Culture, by Ignacio López-Calvo (reviewed by Stephen Wilkinson Pre-Columbian Jamaica, by P. Allsworth-Jones (reviewed by William F. Keegan Underwater and Maritime Archaeology in Latin America and the Caribbean, edited by Margaret E. Leshikar-Denton & Pilar Luna Erreguerena (reviewed by Erika Laanela

  20. Implementing an Internet-Delivered Skin Cancer Genetic Testing Intervention to Improve Sun Protection Behavior in a Diverse Population: Protocol for a Randomized Controlled Trial.

    Science.gov (United States)

    Hay, Jennifer L; Berwick, Marianne; Zielaskowski, Kate; White, Kirsten Am; Rodríguez, Vivian M; Robers, Erika; Guest, Dolores D; Sussman, Andrew; Talamantes, Yvonne; Schwartz, Matthew R; Greb, Jennie; Bigney, Jessica; Kaphingst, Kimberly A; Hunley, Keith; Buller, David B

    2017-04-25

    average-risk personalized genomic testing for melanoma risk findings, and examine predictors of sun protection at 3 months as the outcome. These findings will be used to develop messages for groups that receive average-risk feedback. Aim 2 will compare rates of test consideration in Hispanics versus non-Hispanics, including consideration of testing pros and cons and registration of a decision to either accept or decline testing. Aim 3 will examine personalized genomic testing for melanoma risk feedback comprehension, recall, satisfaction, and cancer-related distress in those who undergo testing, and whether these outcomes differ by ethnicity (Hispanic vs non-Hispanic), or sociocultural or demographic factors. Final outcome data collection is anticipated to be complete by October 2017, at which point data analysis will commence. This study has important implications for personalized genomics in the context of melanoma risk, and may be broadly applicable as a model for delivery of personalized genomic feedback for other health conditions. ©Jennifer L Hay, Marianne Berwick, Kate Zielaskowski, Kirsten AM White, Vivian M Rodríguez, Erika Robers, Dolores D Guest, Andrew Sussman, Yvonne Talamantes, Matthew R Schwartz, Jennie Greb, Jessica Bigney, Kimberly A Kaphingst, Keith Hunley, David B Buller. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 25.04.2017.

  1. Antimicrobial photodynamic activity and cytocompatibility of Au25(Capt18 clusters photoexcited by blue LED light irradiation

    Directory of Open Access Journals (Sweden)

    Miyata S

    2017-04-01

    Full Text Available Saori Miyata,1 Hirofumi Miyaji,1 Hideya Kawasaki,2 Masaki Yamamoto,2 Erika Nishida,1 Hiroko Takita,3 Tsukasa Akasaka,4 Natsumi Ushijima,3 Toshihiko Iwanaga,5 Tsutomu Sugaya1 1Department of Periodontology and Endodontology, Hokkaido University Graduate School of Dental Medicine, Kita-ku, Sapporo, 2Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University, Suita-shi, Osaka, 3Support Section for Education and Research, Hokkaido University Graduate School of Dental Medicine, 4Department of Biomedical, Dental Materials and Engineering, Graduate School of Dental Medicine, Hokkaido University, 5Department of Anatomy, Laboratory of Histology and Cytology, Hokkaido University Graduate School of Medicine, Kita-ku, Sapporo, Japan Abstract: Antimicrobial photodynamic therapy (aPDT has beneficial effects in dental treatment. We applied captopril-protected gold (Au25(Capt18 clusters as a novel photosensitizer for aPDT. Photoexcited Au clusters under light irradiation generated singlet oxygen (1O2. Accordingly, the antimicrobial and cytotoxic effects of Au25(Capt18 clusters under dental blue light-emitting diode (LED irradiation were evaluated. 1O2 generation of Au25(Capt18 clusters under blue LED irradiation (420–460 nm was detected by a methotrexate (MTX probe. The antimicrobial effects of photoexcited Au clusters (0, 5, 50, and 500 µg/mL on oral bacterial cells, such as Streptococcus mutans, Aggregatibacter actinomycetemcomitans, and Porphyromonas gingivalis, were assessed by morphological observations and bacterial growth experiments. Cytotoxicity testing of Au clusters and blue LED irradiation was then performed against NIH3T3 and MC3T3-E1 cells. In addition, the biological performance of Au clusters (500 µg/mL was compared to an organic dye photosensitizer, methylene blue (MB; 10 and 100 µg/mL. We confirmed the 1O2 generation ability of Au25(Capt18 clusters through the fluorescence

  2. Defining the benefits and challenges of stakeholder engagement in systematic reviews

    Directory of Open Access Journals (Sweden)

    Cottrell EK

    2015-04-01

    Full Text Available Erika K Cottrell,1 Evelyn P Whitlock,2 Elisabeth Kato,3 Stacey Uhl,4 Suzanne Belinson,5 Christine Chang,3 Ties Hoomans,5,6 David O Meltzer,5,7 Hussein Noorani,5 Karen A Robinson,8 Makalapua Motu'apuaka,9 Johanna Anderson,9 Robin A Paynter,9 Jeanne-Marie Guise9 1Oregon Health and Sciences University, Portland, OR, USA; 2Kaiser Evidence-based Practice Center, Portland, OR, USA; 3Agency for Healthcare Research and Quality, Rockville, MD, USA; 4ECRI-Penn Evidence-based Practice Center, Plymouth Meeting, PA, USA; 5Office of Clinical Affairs, Blue Cross Blue Shield Association, Chicago, IL, USA; 6Institute of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, the Netherlands; 7University of Chicago, Chicago, IL, USA; 8Johns Hopkins University Evidence-based Practice Center, Baltimore, MD, USA; 9Scientific Resource Center for the Agency for Healthcare Research and Quality (AHRQ Effective Health Care Program, Portland Veterans Affairs (VA Research Foundation, Portland VA Medical Center, Portland, OR, USA Background: Although there is a growing literature on the process of engaging stakeholders in medical research, there are a lack of clearly-defined measures for reporting and evaluation, which limits the ability to learn from past experience, understand the effectiveness of engagement, or identify which approaches work best. Clearly defining the benefits and challenges of engaging stakeholders in the systematic review process is an integral first step toward developing a set of criteria that can be used to evaluate the impact and effectiveness on the conduct, quality, and dissemination of systematic reviews. Methods: We utilized two complementary approaches to examine the benefits and challenges of engaging stakeholders in the systematic review process: 1 a literature scan to understand the overall state of the field; and 2 a series of key informant interviews with systematic reviewers, program/policy officials, and stakeholders

  3. ‘Friendly allies in raising a child’: a survey of men and women seeking elective co-parenting arrangements via an online connection website

    Science.gov (United States)

    Jadva, V.; Freeman, T.; Tranfield, E.; Golombok, S.

    2015-01-01

    with the mother or to live equally in both households. A higher proportion of gay and bisexual men than heterosexual men wanted daily contact with the child. LIMITATIONS, REASONS FOR CAUTION Although this study presents data from the largest sample of elective co-parents to date, the main limitations were the low response rate and that only members of one website were approached. The findings may not be representative of all potential elective co-parents. WIDER IMPLICATIONS OF THE FINDINGS This study provides important insights into the new phenomenon of elective co-parenting. With the increasing use of assisted reproductive technologies and the diversification of family forms, a growing number of people are seeking co-parenting arrangements to have children. While up until now, elective co-parenting has been principally associated with the gay and lesbian community, this study shows that, with the rise of co-parenting websites, increasing numbers of heterosexual men and women are seeking these types of parenting arrangements. This study generates the first findings on the expectations and motivations of those who seek co-parents online and examines whether these differ according to gender and sexual orientation. Future studies are needed to assess the impact of this new form of parenting on all involved, particularly the children. STUDY FUNDING/COMPETING INTEREST(S) This study was supported by the Wellcome Trust (097857/Z/11/Z). Erika Tranfield is the co-founder of the website Pride Angel, the remaining authors have no conflicts of interest to declare. PMID:26040481

  4. Assessing quality of life in the treatment of patients with age-related macular degeneration: clinical research findings and recommendations for clinical practice

    Directory of Open Access Journals (Sweden)

    Yuzawa M

    2013-07-01

    Full Text Available Mitsuko Yuzawa,1 Kyoko Fujita,1 Erika Tanaka,2 Edward C Y Wang21Department of Ophthalmology, Nihon University School of Medicine, Surugadai, Kanda, Chiyoda-ku, Tokyo, Japan; 2Health Economics and Outcomes Research, Bayer Yakuhin Ltd, Marunouchi, Chiyoda-ku, Tokyo, JapanBackground: The importance of incorporating quality-of-life (QoL assessments into medical practice is growing as health care practice shifts from a “disease-based” to a “patient-centered” model. The prevalence of age-related macular degeneration (AMD is increasing in today’s aging population. The purpose of this paper is: (1 to discuss, by reviewing the current literature, the impact of AMD on patients’ QoL and the utility of QoL assessments in evaluating the impact of AMD and its treatment; and (2 to make a recommendation for incorporating QoL into clinical practice.Methods: We conducted a PubMed and an open Internet search to identify publications on the measurement of QoL in AMD, as well as the impact of AMD and the effect of treatment on QoL. A total of 28 articles were selected.Results: AMD has been found to cause a severity-dependent decrement in QoL that is comparable to systemic diseases such as cancer, ischemic heart disease, and stroke. QoL impairment manifests as greater social dependence, difficulty with daily living, higher rates of clinical depression, increased risk of falls, premature admission to nursing homes, and suicide. The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25 is the most widely used eye disease-specific QoL instrument in AMD. It has been shown to correlate significantly with visual acuity (VA. QoL reflects aspects of AMD including psychological well-being, functional capacity, and the ability to perform patients’ valued activities, which are not captured by a single, numerical VA score.Conclusion: The literature shows that the adverse impact of AMD on QoL is comparable to serious systemic disease. Eye disease

  5. Cost-effective therapeutic hypothermia treatment device for hypoxic ischemic encephalopathy

    Directory of Open Access Journals (Sweden)

    Allen RH

    2013-01-01

    Full Text Available John J Kim,1,2 Nathan Buchbinder,1,† Simon Ammanuel,1,4,5,† Robert Kim,1,† Erika Moore,1 Neil O'Donnell,1 Jennifer K Lee,3 Ewa Kulikowicz,3 Soumyadipta Acharya,1 Robert H Allen,1,9 Ryan W Lee,6,7 Michael V Johnston4–81Department of Biomedical Engineering, Whiting School of Engineering, The Johns Hopkins University, 2The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins University School of Medicine, 3Department of Anesthesia and Critical Care Medicine, Johns Hopkins University, 4Kennedy Krieger Institute, 5Hugo W Moser Research Institute, 6Department of Neurology, 7Department of Pediatrics, 8Department of Physical Medicine and Rehabilitation Johns Hopkins University School of Medicine, Baltimore, MD; 9Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA†These authors contributed equally to this workAbstract: Despite recent advances in neonatal care and monitoring, asphyxia globally accounts for 23% of the 4 million annual deaths of newborns, and leads to hypoxic-ischemic encephalopathy (HIE. Occurring in five of 1000 live-born infants globally and even more in developing countries, HIE is a serious problem that causes death in 25%–50% of affected neonates and neurological disability to at least 25% of survivors. In order to prevent the damage caused by HIE, our invention provides an effective whole-body cooling of the neonates by utilizing evaporation and an endothermic reaction. Our device is composed of basic electronics, clay pots, sand, and urea-based instant cold pack powder. A larger clay pot, lined with nearly 5 cm of sand, contains a smaller pot, where the neonate will be placed for therapeutic treatment. When the sand is mixed with instant cold pack urea powder and wetted with water, the device can extract heat from inside to outside and maintain the inner pot at 17°C for more than 24 hours with monitoring by LED lights and thermistors

  6. 'Friendly allies in raising a child': a survey of men and women seeking elective co-parenting arrangements via an online connection website.

    Science.gov (United States)

    Jadva, V; Freeman, T; Tranfield, E; Golombok, S

    2015-08-01

    . Although this study presents data from the largest sample of elective co-parents to date, the main limitations were the low response rate and that only members of one website were approached. The findings may not be representative of all potential elective co-parents. This study provides important insights into the new phenomenon of elective co-parenting. With the increasing use of assisted reproductive technologies and the diversification of family forms, a growing number of people are seeking co-parenting arrangements to have children. While up until now, elective co-parenting has been principally associated with the gay and lesbian community, this study shows that, with the rise of co-parenting websites, increasing numbers of heterosexual men and women are seeking these types of parenting arrangements. This study generates the first findings on the expectations and motivations of those who seek co-parents online and examines whether these differ according to gender and sexual orientation. Future studies are needed to assess the impact of this new form of parenting on all involved, particularly the children. This study was supported by the Wellcome Trust (097857/Z/11/Z). Erika Tranfield is the co-founder of the website Pride Angel, the remaining authors have no conflicts of interest to declare. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology.

  7. Silencing of Foxp3 delays the growth of murine melanomas and modifies the tumor immunosuppressive environment

    Directory of Open Access Journals (Sweden)

    Franco-Molina MA

    2016-01-01

    Full Text Available Moisés A Franco-Molina,* Diana F Miranda-Hernández,* Edgar Mendoza-Gamboa, Pablo Zapata-Benavides, Erika E Coronado-Cerda, Crystel A Sierra-Rivera, Santiago Saavedra-Alonso, Reyes S Taméz-Guerra, Cristina Rodríguez-Padilla Immunology and Virology Department, Biological Sciences Faculty, University Autonoma of Nuevo León (UANL, San Nicolás de los Garza, Nuevo León, Mexico*These authors contributed equally to this work Abstract: Forkhead box p3 (Foxp3 expression was believed to be specific for T-regulatory cells but has recently been described in non-hematopoietic cells from different tissue origins and in tumor cells from both epithelial and non-epithelial tissues. The aim of this study was to elucidate the role of Foxp3 in murine melanoma. The B16F10 cell line Foxp3 silenced with small interference Foxp3 plasmid transfection was established and named B16F10.1. These cells had lower levels of Foxp3 mRNA (quantitative real-time reverse transcription-polymerase chain reaction [0.235-fold], protein (flow cytometry [0.02%], CD25+ expression (0.06%, cellular proliferation (trypan blue staining, and interleukin (IL-2 production (enzyme-linked immunosorbent assay [72.35 pg/mL] than those in B16F10 wild-type (WT cells (P<0.05. Subcutaneous inoculation of the B16F10.1 cell line into C57BL/6 mice delayed the time of visible tumor appearance, increased the time of survival, and affected the weight of tumors, and also decreased the production of IL-10, IL-2, and transforming growth factor beta compared with mice inoculated with the B16F10 WT cell line. The B16F10.1 cells derived from tumors and free of T-cells (isolated by Dynabeads and plastic attachment expressed relatively lower levels of Foxp3 and CD25+ than B16F10 WT cells (P<0.05 in a time-dependent manner. The population of tumor-infiltrating lymphocytes of T CD4+ cells (CD4+, CD4+CD25+, and CD4+CD25+Foxp3+ increased in a time-dependent manner (P<0.05 in tumors derived from B16F10 WT cells

  8. FOREWORD: The 70th birthday of Professor Stig Stenholm The 70th birthday of Professor Stig Stenholm

    Science.gov (United States)

    Suominen, Kalle-Antti

    2010-09-01

    researchers such as Marc-Andre Dupertuis and Steve Barnett worked with Stig at TFT, and in the 1990s it was the turn of Barry Garraway, Ilkka Tittonen and Nikolay Vitanov among others. For his work in 1992-1997 Stig Stenholm received the prestigious Academy of Finland Professorship which provided him with valuable research funds. My graduation in 1992 was followed by Mackillo Kira in 1995 and Päivi Törmä in 1996. Following developments in the field, in the mid-1990s Stig started to work on Bose-Einstein condensation and quantum information. Later he had a Humboldt fellowship, with stays in Germany shared by the Universities at Konstanz (Jürgen Mlynek) and Ulm (Wolfgang Schleich). Unfortunately, the University of Helsinki decided to replace TFT and a corresponding experimental particle physics institute with a new institute, which was mostly seen as the Finnish front-end for CERN collaboration; in 1997 the Helsinki Institute of Physics (HIP) was started. Although the activities of TFT still existed in the theory section of HIP, many things and especially the atmosphere were changed and in 1997 this partly led Stig to accept a position at the Royal Institute of Technology in Stockholm, Sweden, where two of his Finnish students, Patrik Öhberg and Erika Andersson graduated shortly after the move. I moved to HIP at the time, but left for a position in Turku in 2000, and the quantum optics project was finally switched off at HIP in 2003—only later it was found that quantum optics had provided the Institute with its most cited papers, propelling it into the top 5 percent most cited institutes in its field (especially thanks to Norbert Lütkenhaus and his work on quantum cryptography). The time in Stockholm was fruitful for Stig scientifically, but he also became a member of the Royal Swedish Academy of Sciences, and although Nobel committee papers remain secret for 50 years, it is likely that he had a hand in its activities. In 2005 we jointly published a textbook on quantum

  9. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1997-07-01

    Full Text Available -Leslie G. Desmangles, Joan Dayan, Haiti, history, and the Gods. Berkeley: University of California Press, 1995. xxiii + 339 pp. -Barry Chevannes, James T. Houk, Spirits, blood, and drums: The Orisha religion in Trinidad. Philadelphia: Temple University Press, 1995. xvi + 238 pp. -Barry Chevannes, Walter F. Pitts, Jr., Old ship of Zion: The Afro-Baptist ritual in the African Diaspora. New York: Oxford University Press, 1993. xvi + 199 pp. -Robert J. Stewart, Lewin L. Williams, Caribbean theology. New York: Peter Lang, 1994. xiii + 231 pp. -Robert J. Stewart, Barry Chevannes, Rastafari and other African-Caribbean worldviews. London: Macmillan, 1995. xxv + 282 pp. -Michael Aceto, Maureen Warner-Lewis, Yoruba songs of Trinidad. London: Karnak House, 1994. 158 pp.''Trinidad Yoruba: From mother tongue to memory. Tuscaloosa: University of Alabama Press, 1996. xviii + 279 pp. -Erika Bourguignon, Nicola H. Götz, Obeah - Hexerei in der Karibik - zwischen Macht und Ohnmacht. Frankfurt am Main: Peter Lang, 1995. 256 pp. -John Murphy, Hernando Calvo Ospina, Salsa! Havana heat: Bronx Beat. London: Latin America Bureau, 1995. viii + 151 pp. -Donald R. Hill, Stephen Stuempfle, The steelband movement: The forging of a national art in Trinidad and Tobago. Philadelphia: University of Pennsylvania Press, 1995. xx + 289 pp. -Hilary McD. Beckles, Jay R. Mandle ,Caribbean Hoops: The development of West Indian basketball. Langhorne PA: Gordon and Breach, 1994. ix + 121 pp., Joan D. Mandle (eds -Edmund Burke, III, Lewis R. Gordon ,Fanon: A critical reader. Oxford: Blackwell, 1996. xxi + 344 pp., T. Denean Sharpley-Whiting, Renée T. White (eds -Keith Alan Sprouse, Ikenna Dieke, The primordial image: African, Afro-American, and Caribbean Mythopoetic text. New York: Peter Lang, 1993. xiv + 434 pp. -Keith Alan Sprouse, Wimal Dissanayake ,Self and colonial desire: Travel writings of V.S. Naipaul. New York : Peter Lang, 1993. vii + 160 pp., Carmen Wickramagamage (eds

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1996-01-01

    Full Text Available -Sandra L. Richards, Judy S.J. Stone, Theatre. London: Macmillan Caribbean, 1994. xii + 268 pp. -Lowell Fiet, Errol Hill, The Jamaican stage, 1655-1900: profile of a colonial theatre. Amherst: University of Massachusetts Press, 1992. xiv + 346 pp. -Supriya Nair, Bruce King, V.S. Naipaul. New York: St. Martin's Press, 1993. viii + 170 pp. -Agnes Lugo-Ortiz, Donald E. Rice, The rhetorical uses of the authorizing figure: Fidel Castro and José Martí. Westport CT: Praeger, 1992. xviii + 163 pp. -Graciella Cruz-Taura, Juan A. Martínez, Cuban art and national identity: The Vanguardia painters, 1927-1950. Gainesville: University Press of Florida, 1994. xiv + 189 pp. -Graciella Cruz-Taura, Luis Camnitzer, New art of Cuba. Austin; University of Texas Press, 1994. xxx + 400 pp. -Gary Brana-Shute, Richard Price ,On the mall: Presenting Maroon tradition-bearers at the 1992 festival of American folklife. Bloomington: Folklore Institute, Indiana University, 1994. xi + 123 pp., Sally Price (eds -Erika Bourguignon, Stephan Palmié, Das Exil der Götter: Geschichte und Vorstellungswelt einer afrokubanischen Religion. Frankfurt: Peter Lang, 1991. vii + 520 pp. -Carla Freeman, Daniel Miller, Modernity, an ethnographic approach: Dualism and mass consumption in Trinidad. Oxford: Berg Publishers, 1994. 340 pp. -Daniel A. Segal, Kelvin Singh, Race and class: Struggles in a colonial state: Trinidad 1917-1945. Kingston; The Press - University of the West Indies, 1994. xxii + 284 pp. -Evelyne Huber, Patsy Lewis, Jamaica: Preparing for the twenty-first century. Kingston: Ian Randle, 1994. xvi + 272 pp. -Diane Vernon, Elisa Janine Sobo, One blood: The Jamaican body. Albany NY: State University of New York Press, 1993. vii + 329 pp. -Robert Myers, Patrick L. Baker, Centring the periphery: Chaos. order and the ethnohistory of Dominica. Kingston: The Press - University of the West Indies, 1994. xxviii + 251 pp. -Riva Berleant-Schiller, Debra Evenson, Revolution in the

  11. A revision of the shore-fly genus Hydrochasma Hendel (Diptera, Ephydridae).

    Science.gov (United States)

    Mathis, Wayne N; Zatwarnicki, Tadeusz

    2013-01-01

    A revision of the shore-fly genus Hydrochasma Hendel. The species of the genus Hydrochasma Hendel are revised, including 27 new species (type locality in parenthesis): H. andeum (Ecuador. Guayas: Boliche (02°07.7'S, 79°35.5'W)), H. annae (United States. Utah. Grand: Swasey Beach (15.3 km N Green River; 39°07'N, 110°06.6'W; Green River; 1255 m)), H. capsum (Ecuador. Orellana: RíoTiputini (0°38.2'S, 76°8.9'W)), H. castilloi (Ecuador. Loja: Catamayo (03°59'S, 79°21'W)), H. crenulum (Peru. Cuzco: Paucartambo, Atalaya (Río Alto Madre de Dios; 12°53.3'S, 71°21.6'W; 600 m)), H. denticum (Ecuador. Orellana: Río Tiputini (0°38.2'S, 76°8.9'W)), H. digitatum (Peru. Madre de Dios: Diamante (Río Alto Madre de Dios; 12°19.9'S, 70°57.5'W; 400 m)), H. distinctum (Costa Rica. Limón: Parque Nacional Barbilla, Sector Casas Negras, (10°0.8'N, 83°28.1'W; 300 m)), H. dolabrutum (Dominican Republic. Barahona: Barahona (18°12'N, 71°5.3'W)), H. edmistoni (Dominican Republic. Azua: near Pueblo Viejo (18°24.8'N, 70°44.7'W)), H. falcatum (Peru. Madre de Dios: Río Manu, Erika (near Salvación; 12°50.7'S, 71°23.3'W; 550 m)), H. glochium (Dominican Republic. Peravia: San José Ocoa (10 km NE; 18°35'N, 70°25.6'W)), H. kaieteur (Guyana. Kaieteur Falls (05°10.5'N, 59°26.9'W)), H. lineatum (Trinidad and Tobago. Trinidad. St. George: Filette (1 km SE; 10°47'N, 61°21'W)), H. miguelito (Honduras. Cortés: San Pedro Sula (8 km S; 15°25.7'N, 88°01.4'W)), H. octogonum (Ecuador. Manabí: Pichincha (01°02.7'S, 79°49.2'W)), H. parallelum (Trinidad and Tobago. Trinidad. St. Andrew: Lower Manzanilla (16 km S; 10°22'N, 61°01'W)), H. peniculum (Dominican Republic. Pedernales: Pedernales (18°01.8'N, 71°44.7'W)), H. rictum (Honduras. Cortés: San Pedro Sula (8 km S; 15°25.7'N, 88°01.4'W)), H. robustum (Brazil. São Paulo. Ubatuba, Praia Puruba (23°21'S, 44°55.6'W; beach)), H. sagittarium (Trinidad and Tobago. Tobago: St. John: Parlatuvier (creek; 11°17.9'N, 60°35'W

  12. AAS 227: Day 1

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    how it evolves over time. Heres the press release.The final speaker was grad studentSamuel Grunblatt (University of Hawaii Institute for Astronomy), who spoke about measuring the mass of exoplanets around active stars. In radial velocity studies of exoplanets, a planet orbiting its star causes the star to wobble. This signal for an Earth-like planet is as tiny as 9 cm/s! Unfortunately, activity of the star can cause radial velocity noise of 1-10 m/s so to detect Earth-like planets, we need to find a way of subtracting off the noise. Grunblatt talked about an intriguing new method for determining planet masses that controls for the signature of their hosts activity. Heres his paper.Annie Jump Cannon Award Lecture: On the Dynamics of Planets, Stars and Black Holes (by Erika Nesvold)This year, the Annie Jump Cannon Award was given to Smadar Naoz, an assistant professor at UCLA. The Cannon Award is given every year to a young (less than 5 years since PhD), female astronomer for outstanding work in her field. Traditionally, the Cannon Award recipient delivers a lecture on her research, so this year we were lucky to see a dynamic and engaging talk by Smadar Naoz about her research in dynamical theory.You may have heard the common career advice that you should focus on becoming the expert on one particular facet of astronomy: a particular type of object, an observational technique, a type of instrument, etc. Naoz has managed to follow that advice while still managing to study a huge range of astronomical topics, from exoplanets to cosmology. She studies hierarchical triples, systems of three gravitational bodies in which two of the bodies orbit one another very closely, while the third orbits the other two from a much greater distance. For example, a planet in a tight orbit around a star, with a brown dwarf orbiting hundreds of AU away, make up a hierarchical triple system. So does a system in which two black holes orbit each other closely, with a third black hole orbiting

  13. Pühaduse performatiivsus ja kristlik teater / The Performativity of Sacrality and Christian Theatre

    Directory of Open Access Journals (Sweden)

    Madis Kolk

    2015-06-01

    s prior determinations, which emphasizes first, that sacred theatre induces a change of consciousness in which the subject and the object merge; second, the liminality of the intersubjective environment surrounding the experience of the sacred, in which the verbal and the transcendental unite. When describing the influence of the logocentrism of Christian culture on the experience of sacredness, Yarrow draws on the views of Mark C. Taylor, Rudolf Otto, Mircea Eliade and Georges Bataille. All of these thinkers critique the rationalism attributed to monotheistic religion, which gives an important place to Christ as the mediator of God’s transcendental truth, the logos, and sacred scripture, all of which differ from the numinous experience of the mystic. The art of so-called sacred theatre, where, at least according to tradition, the performative mission, dramaturgy, stage design, and public reception are all part of a unified contemplative whole seems to be missing in Western culture. Indeed, this is what several Western stage experimenters have been looking for, and in their search they have looked eastward. New viewpoints with respect to the perception of a work of art were gained in the „performative turn“ of the end of the 20th century; besides the text, proponents of this new direction became interested in the sensory and bodily processes of creativity and reception. Erika Fischer-Lichte and others have conceptualized these processes on a more general level and reflected upon the aesthetics of performativity; insodoing they have pointed to a dualism in the Western aesthetics of performativity, recognizing that there is a contradiction between the referential, semiotic pole of art and its performative dimension. Although the reasons for this split can be sought in the very origins of Western art as well as that of medieval Christian art, relations between theatre and the church differ according to confession; Yarrow’s definitions do not apply to Christianity as

  14. AAS 227: Day 3

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Welcome to Day 3 of the winter American Astronomical Society (AAS) meeting in Kissimmee! Several of us are attending the conference this year, and we will report highlights from each day here on astrobites. If youd like to see more timely updates during the day, we encourage you to follow @astrobites on twitter or search the #aas227 hashtag.Henry Norris Russell Lecture: Viewing the Universe with Infrared Eyes: The Spitzer Space Telescope (by Erika Nesvold)The Henry Norris Russell Award is the highest honor given by the AAS, for a lifetime of eminence in astronomy research. This years award went to Giovanni Fazio of the Harvard-Smithsonian Center for Astrophysics. Fazio became a leader in gamma ray astronomy before switching mid-career to the study of infrared astronomy, and he gave his award lecture on the latter subject, specifically on the Spitzer Space Telescope, one of the most successful infrared telescopes of all time.Artists rendering of the Spitzer space telescope. [NASA/JPL-Caltech]Spitzer has been operating for more than twelve years, and has resulted in over six thousand papers in refereed journals in that time. The telescope sits in an Earth-trailing orbit around the Sun, and is now farther from the Earth (1.4 AU) than the Earth is from the Sun. Fazio gave the audience a fascinating overview of the science done by Spitzer over more than a decade. One of the most productive areas of research for Spitzer is the study of exoplanets, which hadnt even been discovered when the Spitzer Telescope was first conceived. Spitzers high sensitivity and ability to observe exoplanets over

  15. Editorial volume 3 - issue 1: Wishes and hopes for the digital university.

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2007-12-01

    survive as the most prestigious activity in U.S. universities, as it is in most European ones. In addition, the tendency is strong towards deeper polarization between research and teaching positions. Also, a rapid growth in the employment of part-time non-tenured teachers in the US poses a significant challenge to the traditional structure of employment. About one half of the faculty members in the U.S. are now part-time (Rice, Finkelstein, Hall & Schuster 2004. Most of these part time academics are doing teaching, and many of them are associated with online teaching and learning. Some have hopes and dreams about making repetitive work simpler and automated, like paying invoices. Handling teaching and learning is a totally different issue. If the case is that using technology will be outsourced to part-time personnel or restricted to learning centres etc. we shall miss the opportunity of addressing the more profound issues about technology, teaching and learning. Douglas Kellner (2001 argues that these issues are so serious that, much more than before, they “require a reformulation and expansion of the concept of critical or committed intellectual”. And there are numerous good reasons. If critical intellectuals do not commit themselves to investigating both risks and promises, other institutions, mainly commercial, will fill the gap. Higher education needs to become involved and set standards for the critical and reflective use of educational technology. Burbules and Callister jr. anticipate that ”Colleges and universities will change because of pressures from the outside as well as conscious decisions made from the inside, and technologies will be incorporated, in some ways and to some degree, in everything that colleges and universities try to do.” (ibid. p.7. The articles presented in this issue address such topics in many ways. Training university teachers to use online learning in a critical way is the topic Erika Løfstrøm and Anne Nevgi address in this

  16. EDITORIAL: Colloidal suspensions Colloidal suspensions

    Science.gov (United States)

    Petukhov, Andrei; Kegel, Willem; van Duijneveldt, Jeroen

    2011-05-01

    Colloid-polymer mixtures and depletion interactions Phase stability of a reversible supramolecular polymer solution mixed with nanospheres Remco Tuinier When depletion goes critical Roberto Piazza, Stefano Buzzaccaro, Alberto Parola and Jader Colombo Tuning the demixing of colloid-polymer systems through the dispersing solvent E A G Jamie, R P A Dullens and D G A L Aarts Polydispersity effects in colloid-polymer mixtures S M Liddle, T Narayanan and W C K Poon Colloidal dynamics and crystallization Crystallization and aging in hard-sphere glasses C Valeriani, E Sanz, E Zaccarelli, W C K Poon, M E Cates and P N Pusey Real-time monitoring of complex moduli from micro-rheology Taiki Yanagishima, Daan Frenkel, Jurij Kotar and Erika Eiser Brownian motion of a self-propelled particle B ten Hagen, S van Teeffelen and H Löwen Crystallization in suspensions of hard spheres: a Monte Carlo and molecular dynamics simulation study T Schilling, S Dorosz, H J Schöpe and G Opletal Structural signature of slow dynamics and dynamic heterogeneity in two-dimensional colloidal liquids: glassy structural order Takeshi Kawasaki and Hajime Tanaka

  17. AAS 227: Day 4

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    Editors Note:This week were at the 227th AAS Meeting in Kissimmee, FL. Along with several fellow authors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting at the end of each day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Welcome to Day 4 of the winter American Astronomical Society (AAS) meeting in Kissimmee! Several of us are attending the conference this year, and we will report highlights from each day here on astrobites. If youd like to see more timely updates during the day, we encourage you to follow @astrobites on twitter or search the #aas227 hashtag.Helen B. Warner Prize: Origins of Structure in Planetary Systems (by Erika Nesvold)Another excellent prize lecture started off todays sessions. The Helen B. Warner Prize is awarded for achievement in observational or theoretical astrophysics by a young researcher (no more than eight years after their Ph.D.). This years Warner Prize was presented to Ruth Murray-Clay of UC Santa Barbara. For her award lecture, Murray-Clay told us all about planetary system architecture: the number, masses, and orbits of planets in a given system.Ruth Murray-Clay [photo from http://web.physics.ucsb.edu/ ~murray/biocv.html]The underlying question motivating this type of research is: How rare is the Solar System? In other words, how likely is it that a given planetary system will have rocky planets close to their star, gas giants farther out, and ice giants at the outer reaches of the system? Answering this question will help us solve the physics problem of how and where planets form, and will also help us on our search for other planets like Earth.The data on exoplanet population from transit and radial velocity observations and from direct imaging tell us that our Solar System is not common (many systems we observe have much more eccentric gas giants), but that doesnt

  18. Outcomes From AAS Hack Day at the 227th AAS Meeting

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    Editors Note:This is a final post from the 227th AAS Meeting in Kissimmee, FL. This special summary of AAS Hack Day, a meeting of AAS members to collaboratively work on various small projects, was written by Meredith Rawls (@Merrdiff) and was originally posted on astrobites.com.As the 227thAmerican Astronomical Society meeting drew to a close (see highlights from Day 1, Day 2, Day 3, and Day 4), a group of at least 50 attendees spent Day 4working on small projects fondly called hacks. Thanks to sponsorship from LSST and Northrup Grumman, the industrious hackers werewell-caffeinated and fed so we could devote time and energy toworking in groups on one-day projects.TheHack Day beganat 10am with pitches. Anybody with a project idea was welcome to briefly speak and try to convince others to work with them. Only someideas panned out, but the enthusiasm was palpable. Its not every day you get a full room of astronomers and affiliates eager to spend hours working on fun and useful projects to benefit the community.#hackAAS is getting underway! #aas227 pic.twitter.com/yX7jlOnSCK James R A Davenport (@jradavenport) January 8, 2016Here is a rundown of what we accomplished. Pretty impressive for a single day! Many thanks to fellow astrobiter Erika Nesvold (now at Carnegie DTM; @erikanesvold) whose hack was live-documenting all the other hacks. Her tweets as @astrobites appeared with the #hackaas hashtag, and her notes made this recap post infinitely easier to write.Interested in joining the fun? Sign up for Hack Day at the 2017 JanuaryAAS meeting (its free with meeting registration), and consider applying for the .Astronomy conference this summer.Towards Optimal Session Scheduling:Adrian Price-Whelan (Columbia), David Hogg (NYU), and Scott Idem (AAS) began writing a program to take all submitted abstracts to a conference like AAS and sort them using keywords to avoid scheduling similar talks in parallel sessions. Its impossible to make everyone happy, but minimizing conflicts

  19. AAS 227: Day 2

    Science.gov (United States)

    Kohler, Susanna

    2016-01-01

    tutorial.A Report on the Inclusive Astronomy 2015 Meeting: Community Recommendations for Diversity and Inclusion in AstronomyThis very well-attended session recapped the Inclusive Astronomy 2015 meeting (see this link for a summary!)The IA2015 meeting results can be found here.A draft of the recommendations from IA2015 is here. Note that this document, termed the Nashville Recommendations, is a living document that isnt yet finalized, and feedback is welcome.Dannie Heineman Prize: From ~ to Precision Science: Cosmology from 1995 to 2025 (by Erika Nesvold)Marc Kamionkowski of Johns Hopkins University and David Spergel of Princeton University shared this years Heineman Prize for outstanding work in astronomy, and gave an impressive tag-team overview of the progress in the field of cosmology over the past 20 years.Spergel pointed out that in 1995, cosmologists were still debating over the value of the Hubble constant, and whether or not the universe is flat. Kamionkowski pointed out that back then, cosmology was an order of magnitude game where observations lagged far behind theory. He noted that in general, theorists tend to sit around predicting things, and not much progress is made in testing those predictions, at least not within the lifetime of an individual theorist. In cosmology, however, the measurements and observations made since 1995 have been more successful and precise than anyone could have anticipated.This is thanks in part to the WMAP mission and later the Planck satellite, which measured the cosmic microwave background and collected an amazing set of data. There is excellent agreement between the data from WMAP and Planck, a triumph for observational cosmologists. Much to the surprise of Spergel and other cosmologists, a simple model of only five fundamental parameters fits these data extremely well. Twenty years later, thanks to the hard work of cosmologists, we now know that the age of the universe is 13.8 billion years, and that it is composed of roughly 4

  20. Editorial

    Directory of Open Access Journals (Sweden)

    Fernando Mezadri

    2016-07-01

    e patologizante da condição transexual e das outras manifestações da corporeidade e sexualidade relativas à concepção ontológica dos sujeitos. Em um texto originalmente enviado para o dossiê sobre o ensino da sociologia publicado na última edição da Em Tese, Erika Kulessa de Souza, agracia os leitores com ‘Linguagem e ensino de sociologia: reflexões sobre a apropriação da linguagem’. Nesta produção, a autora propõe uma reflexão sobre o aprendizado da sociologia no ensino médio, considerando aspectos da dimensão linguística como pedra de toque para o desenvolvimento de um olhar sociológico. Ancorando-se em Wittgenstein e Vigotsky, estabelece relações entre o pensamento linguagem e conhecimento, que, mesmo ante oposições epistemológicas em ambos autores, é possível o vislumbre de perspectivas sobre a apropriação da linguagem sociológica. Na mesma linha da sociologia da educação, em ‘O que se entende por educação: as abordagens da sociologia clássica de Durkheim, Weber e Marx’, Fabiane Medina Cruz evidencia a educação como temática chave do processo de consolidação da assim chamada ‘tirania’ de colonização e controle hegemônico desfraldado através da modernidade. Ao servir-se dos sociólogos clássicos – Marx, Durkheim e Weber – a autora reflete sobre paradigmas acerca de temas recorrentes e cotidianos, tal como cidadania, desenvolvimento econômico e identidade nacional, entre outros. Ora, visando fugir de padrões normativos engendrados pela educação, a autora, através das teorias sociológicas clássicas, apresenta possibilidades autônomas para se pensar projetos educacionais. Jorge Botelho Moniz traz uma discussão sobre secularização. Marcadamente situado no campo da Sociologia da Religião, o texto intitulado como ‘A secularização na ultramodernidade católica europeia: uma proposta de análise contextual e multidimensional do fenômeno da secularização’; permite a análise plural sobre