Sample records for er ho lu

  1. Electronic structure of triple intermetallic compounds of RAl/sub 2/Si/sub 2/ type. [(R=Pr,Gd,Tb,Dy,Ho,Er,Tm,Yb,Lu)

    Energy Technology Data Exchange (ETDEWEB)

    Nemoshkalenko, V.V.; Nagornyj, V.Ya.; Mamko, B.P.; Nikolyuk, P.K.; Gel, P.V.; Lutsiv, R.V.; Koterlin, M.D. (AN Ukrainskoj SSR, Kiev. Inst. Metallofiziki; L' vovskij Gosudarstvennyj Univ. (Ukrainian SSR))


    The electron structure of triple intermetallic compounds of RAl/sub 2/Si/sub 2/ type (R=Pr, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu) is studied by X-ray spectral analysis. The study permits an assumption that the studied phases possess covalent bends besides metallic ones.

  2. Subsolidus Phase Relations of the CaO-REOx-CuO Systems (RE = Eu, Tb, Dy, Ho, Er, Lu and Sc) at 900 °C in Air

    DEFF Research Database (Denmark)

    Grivel, Jean-Claude


    The subsolidus phase relations of the CaO-REOx-CuO systems (RE = Eu, Tb, Dy, Ho, Er, Lu and Sc) were investigated in air at 900 °C. The pseudo-ternary sections with RE = Tb, Dy, Ho, Er and Lu have a similar structure. They have in common with the RE = Eu system a solid solution of Ca0.833−xRExCuO2......+y composition but the system with RE = Eu differs by the presence of an Eu2CuO4 phase instead of RE2Cu2O5 for RE = Tb, Dy, Ho, Er and Lu. In contrast, the CaO-ScO1.5-CuO section does not contain a Ca0.833−xScxCuO2+y solid solution and is dominated by the CaSc2O4 phase, which has no equivalent...... in the other systems at 900 °C in air....

  3. Pico- and subpicosecond relaxation processes in lanthanide-porphyrin complexes. [Lanthanoids: Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu

    Energy Technology Data Exchange (ETDEWEB)

    Solov' ev, K.N.; Tsvirko, M.P.; Krasauskas, V.V.; Pyatosin, V.E.; Stel' makh, G.F.


    Methods of nano- and picosecond absorption spectroscopy and luminescence are used to determine the deactivation rates of ..pi.., ..pi..*-electron states of S/sub 2/, S/sub 1/ and T/sub 1/ in complexes of organic molecules of meso-tetratolylporphyne and tetrabenzoporphyne with trivalent Sm/sup 3 +/, Eu/sup 3 +/, Gd/sup 3 +/, Tb/sup 3 +/, Dy/sup 3 +/, Ho/sup 3 +/, Er/sup 3 +/, Tm/sup 3 +/, Yb/sup 3 +/, Lu/sup 3 +/. Quantitative data on superfast relaxation processes in lanthanide porphyrines are obtained. The function of the metal entral ion is presented in details as the excitation factor in deactivation processes of photoexcitation energy of the systems in question.

  4. Study of electronic, magnetic and optical properties of KMS2 (M  =  Nd, Ho, Er and Lu): first principle calculations (United States)

    Ahmed, Nisar; Nisar, Jawad; Kouser, R.; Nabi, Azeem G.; Mukhtar, S.; Saeed, Yasir; Nasim, M. H.


    Wide band gap magnetic semiconductors made of lanthanide compounds have a wide range of applications in opto-magneto-electronic industry and electro (photo) luminescence devices. We have carried out a systematic study of electronic, magnetic and optical properties of rare earth potassium sulfides KMS2 (M  =  Nd, Ho, Er, and Lu) using density functional theory (DFT) with full potential linearized augmented plane wave method (FP-LAPW). Different exchange and correlation approximations are employed such as generalized gradient approximation (GGA), GGA  +  U and TB-mBJ. It is inferred that the GGA  +  U approach correctly predicts the localized behavior of 4f electrons in lanthanide atoms for the calculation of band gaps, electronic, magnetic and optical properties. All compounds are stable in ferromagnetic phase except KLuS2, while KLuS2 is a non-magnetic semiconductor because there is no unpaired f-electron. Band gaps of KMS2 are estimated and these materials are found to be wide band gap semiconductors. These materials absorb mainly ultraviolet (UV) radiations, which make them good photoluminescent materials with a strong dependence on the direction of the polarization of incident photons.

  5. Crystal fields in Sc, Y, and the heavy-rare-earth metals Tb, Dy, Ho, Er, Tm, and Lu

    DEFF Research Database (Denmark)

    Touborg, P.


    -field parameters for all these 15 alloy systems deduced. The consistency of the parameters was confirmed by a variety of magnetic measurements, including neutron spectroscopy. Crystal-field parameters have also been derived for the ions in pure magnetic rare-earth metals and their alloys using the results......—with the inaccuracies somewhat increased—are expected to be representative also for the magnetic rare-earth metals. For rare-earth ions in the Sc host the values B40 / β=9.9±1.9 K, B60 / γ=19.8±1.5 K, and B66 / γ=(9.4±0.9)β60 / γ were deduced. B20 / α is a host-sensitive parameter which has the average values of -102.......7, -53.4, and 29.5 K for rare-earth ions in Y, Lu, and Sc, respectively. There is also evidence that this parameter varies with the solute. B20 / α for ions in the pure magnetic rare-earth metals and their alloys shows a linear variation with c / a ratio characteristic of each ion. The results indicate...

  6. Stabilization of new forms of the intermetallic phases beta-RENiGe2 (RE = Dy, Ho, Er, Tm, Yb, Lu) in liquid indium. (United States)

    Salvador, J R; Gour, J R; Bilc, D; Mahanti, S D; Kanatzidis, M G


    Flux conditions using liquid indium bypass the thermodynamically stable structure and yield new forms of the phases RENiGe2 (RE = Dy, Er, Yb, Lu). The compounds crystallize in the orthorhombic Immm space group and possess the YIrGe2 structure type. Lattice parameters for ErNiGe2, DyNiGe2, YbNiGe2, and LuNiGe2 are a = 4.114(1) A, b = 8.430(2) A, c = 15.741(5) A; a = 4.1784(9) A, b = 8.865(2) A, c = 15.745(3) A; a = 4.0935(6) A, b = 8.4277(13) A, c = 15.751(2) A, and a = 4.092(1) A, b = 8.418(3) A, c = 15.742(5) A, respectively. These phases represent a new structural arrangement (beta) of the compound type RENiGe2 as another set of compounds with identical stoichiometry are known to adopt the orthorhombic Cmcm CeNiSi2 type structure (alpha). In this paper we report the crystal and electronic band structure of four new members of the YIrGe2 structure type, as well as an investigation of the relative thermodynamic stabilities of the two forms.

  7. Demonstration of a hybrid Ho:YLF Ho:LuLF slab laser

    CSIR Research Space (South Africa)

    Esser, MJD


    Full Text Available The authors present a continuous-wave slab laser utilising both Ho:YLF and Ho:LuLF as laser gain media. 30 W of output power at 2 µm was demonstrated in a stable concave-plane resonator while 13 W was achieved in a hybrid stable...

  8. Syntheses, structures, and magnetic properties of a family of heterometallic heptanuclear [Cu5Ln2] (Ln = Y(III), Lu(III), Dy(III), Ho(III), Er(III), and Yb(III)) complexes: observation of SMM behavior for the Dy(III) and Ho(III) analogues. (United States)

    Chandrasekhar, Vadapalli; Dey, Atanu; Das, Sourav; Rouzières, Mathieu; Clérac, Rodolphe


    Sequential reaction of the multisite coordination ligand (LH3) with Cu(OAc)2·H2O, followed by the addition of a rare-earth(III) nitrate salt in the presence of triethylamine, afforded a series of heterometallic heptanuclear complexes containing a [Cu5Ln2] core {Ln = Y(1), Lu(2), Dy(3), Ho(4), Er(5), and Yb(6)}. Single-crystal X-ray crystallography reveals that all the complexes are dicationic species that crystallize with two nitrate anions to compensate the charge. The heptanuclear aggregates in 1-6 are centrosymmetrical complexes, with a hexagonal-like arrangement of six peripheral metal ions (two rare-earth and four copper) around a central Cu(II) situated on a crystallographic inversion center. An all-oxygen environment is found to be present around the rare-earth metal ions, which adopt a distorted square-antiprismatic geometry. Three different Cu(II) sites are present in the heptanuclear complexes: two possess a distorted octahedral coordination sphere while the remaining one displays a distorted square-pyramidal geometry. Detailed static and dynamic magnetic properties of all the complexes have been studied and revealed the single-molecule magnet behavior of the Dy(III) and Ho(III) derivatives.

  9. Polyoxopalladates encapsulating yttrium and lanthanide ions, [X(III)Pd(II)12(AsPh)8O32]5- (X=Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu). (United States)

    Barsukova, Maria; Izarova, Natalya V; Biboum, Rosa Ngo; Keita, Bineta; Nadjo, Louis; Ramachandran, Vasanth; Dalal, Naresh S; Antonova, Nadya S; Carbó, Jorge J; Poblet, Josep M; Kortz, Ulrich


    A series of novel yttrium- and lanthanide-containing heteropolyoxopalladates have been prepared and isolated as hydrated sodium salts, Na(5)[X(III)Pd(II)(12)(AsPh)(8)O(32)]y H(2)O (X=Y (1), Pr (2), Nd (3), Sm (4), Eu (5), Gd (6), Tb (7), Dy (8), Ho (9), Er (10), Tm (11), Yb (12), Lu (13); y=15-27). The polyanions [X(III)Pd(II)(12)(AsPh)(8)O(32)](5-) consist of a cuboid framework of twelve Pd(II) ions with eight phenylarsonate heterogroups located at the vertices and a central guest ion X. The compounds 1-13 have been prepared in a simple one-pot self-assembly reaction of Pd(CH(3)COO)(2), phenylarsonic acid and the respective salt of the element X in 0.5 M aqueous sodium acetate solution (pH 6.9), and characterized in the solid state by single-crystal X-ray diffraction, elemental and thermogravimetric (TGA) analyses, and IR spectroscopy. It was demonstrated that small, medium, and also large lanthanide ions can be incorporated in the center of the novel heteropolypalladate [X(III)Pd(II)(12)(AsPh)(8)O(32)](5-). The Ln-O bond lengths follow the expected trend decreasing from left to right in the lanthanide series. This indicates that the {Pd(II)(12)O(32)} shell can adjust to the coordination requirements of the encapsulated guest cation. Compounds 3 and 5 were selected for electrochemical studies. Their cyclic voltammetry in a lithium acetate buffer at pH 5.9 showed a Pd(0) deposition process on the glassy carbon electrode surface. Coulometry indicated that all Pd(II) centers were reduced to Pd(0). The film was stable and could be taken out of the deposition medium and characterized in pure pH 5.9 buffer. Magnetic susceptibility and EPR measurements were carried out on 5 and 6. The former was confirmed to be diamagnetic and the latter strongly paramagnetic with a S=7/2 ground state. DFT calculations for some of the polyoxometalates have been also performed.

  10. Crystal chemistry and the role of ionic radius in rare earth tetrasilicates: Ba2RE2Si4O12F2 (RE = Er(3+)-Lu(3+)) and Ba2RE2Si4O13 (RE = La(3+)-Ho(3+)). (United States)

    Fulle, Kyle; Sanjeewa, Liurukara D; McMillen, Colin D; Kolis, Joseph W


    Structural variations across a series of barium rare earth (RE) tetrasilicates are studied. Two different formulas are observed, namely those of a new cyclo-silicate fluoride, BaRE2Si4O12F2 (RE = Er(3+)-Lu(3+)) and new compounds in the Ba2RE2Si4O13 (RE = La(3+)-Ho(3+)) family, covering the whole range of ionic radii for the rare earth ions. The Ba2RE2Si4O13 series is further subdivided into two polymorphs, also showing a dependence on rare earth ionic radius (space group P{\\overline 1} for La(3+)-Nd(3+), and space group C2/c for Sm(3+)-Ho(3+)). Two of the structure types identified are based on dinuclear rare earth units that differ in their crystal chemistries, particularly with respect to the role of fluorine as a structural director. The broad study of rare earth ions provides greater insight into understanding structural variations within silicate frameworks and the nature of f-block incorporation in oxyanion frameworks. The single crystals are grown from high-temperature (ca 953 K) hydrothermal fluids, demonstrating the versatility of the technique to access new phases containing recalcitrant rare earth oxides, enabling the study of structural trends.

  11. Návrh rezervačního hotelového portálu


    Rykala, Daniel


    Bakalářská práce se zabývá návrhem webového rezervačního portálu pro ubytovací zařízení, jako jsou hotely a penziony. Výchozím aspektem jsou požadavky zadavatele. V práci je popsán návrh postupu tvorby portálu, posouzení jeho ekonomické hodnoty a zhodnocení jeho případného nasazení do provozu. This Bachelor’s thesis is focused on the design of hotel reservation through web portal, used by accommodation facilities such as hotels . Initial aspects are client’s requests. The thesis describes ...

  12. Phase relationships in the {Ho, Er}–Ni–Sn ternary systems at 673 K and crystal structure of new ternary compounds

    Energy Technology Data Exchange (ETDEWEB)

    Romaka, L., E-mail: [Ivan Franko L’viv National University, Kyryl & Mephodiy Str. 6, 79005 L’viv (Ukraine); Romaniv, I. [Ivan Franko L’viv National University, Kyryl & Mephodiy Str. 6, 79005 L’viv (Ukraine); Romaka, V.V. [Lviv Polytechnic National University, Ustyyanovycha Str. 5, 79013 Lviv (Ukraine); Pavlyuk, V. [Ivan Franko L’viv National University, Kyryl & Mephodiy Str. 6, 79005 L’viv (Ukraine)


    Highlights: • Ho–Ni–Sn and Er–Ni–Sn phase diagrams were constructed at 673 K. • Eight ternary compounds exist in both investigated systems. • HoNi{sub x}Sn{sub 2} (up to 7 at.% Ni) and ErNi{sub x}Sn{sub 2} (up to 5 at.% Ni) solid solutions were found. - Abstract: The phase equilibria of the Ho–Ni–Sn and Er–Ni–Sn ternary systems were studied at 673 K in the whole concentration range using electron probe microanalysis (EPMA) and X-ray powder diffraction (XPD). Each system is characterized by formation of eight ternary compounds at 673 K: Ho{sub 6}Ni{sub 2}Sn, Er{sub 6}Ni{sub 2}Sn (Ho{sub 6}Ni{sub 2}Ga-type), Ho{sub 2}Ni{sub 2}Sn, Er{sub 2}Ni{sub 2}Sn (Mo{sub 2}FeB{sub 2}-type), HoNi{sub 5}Sn, ErNi{sub 5}Sn (CeCu{sub 4.38}In{sub 1.62}-type), HoNi{sub 1.73}Sn, ErNi{sub 1.72}Sn (YbNi{sub 1.705}Sn-type), HoNiSn, ErNiSn (TiNiSi-type), HoNiSn{sub 2}, ErNiSn{sub 2} (LuNiSn{sub 2}-type), HoNiSn{sub 4}, ErNiSn{sub 4} (LuNiSn{sub 4}-type), and Ho{sub 2}NiSn{sub 6}, Er{sub 2}NiSn{sub 6} (Lu{sub 2}NiSn{sub 6}-type). The interstitial solid solutions HoNi{sub x}Sn{sub 2} (up to 7 at.% Ni) and ErNi{sub x}Sn{sub 2} (up to 5 at.% Ni) based on the RSn{sub 2} (ZrSi{sub 2}-type) binary compounds were found.

  13. Ho:YLF & Ho:LuLF slab amplifier system delivering 200 mJ, 2 µm single-frequency pulses

    CSIR Research Space (South Africa)

    Strauss, HJ


    Full Text Available A single-frequency single-pass amplifier based on Ho:YLF and Ho:LuLF in a scalable slab architecture delivering up to 210 mJ at 2064 nm is demonstrated. The amplifier was end-pumped by a 1890 nm Tm:YLF slab laser and was seeded with a 69 mJ single...

  14. Magnetic phase diagram of Ho/Er alloys

    DEFF Research Database (Denmark)

    Cowley, R.A.; Simpson, J.A.; Bryn-Jacobsen, C.


    are found, arising from the competition between the exchange and anisotropic crystal-field interactions, the latter of which are of opposite sign for Ho and Er. The magnetic phase diagram has five distinct phases with long-range magnetic order: basal-plane helical, tilted helical, cycloidal, c......-axis longitudinally modulated, and conical. The cycloid and tilted helix have both incommensurate and commensurate q = 1/4c* forms, and all of the thin films have a conical structure at low temperatures, even though corresponding films of pure Ho and Er do not exhibit this phase. There is a pentacritical point......, and probably a disordered phase which is completely surrounded in the phase diagram by magnetic phases with long-range order. A Landau theory is developed to describe these results....

  15. New microarchitectures of (Er, Yb): Lu2O3 nanocrystals embedded in PMMA: synthesis, structural characterization and luminescent properties


    Díaz, F; Aguiló, M.; Kim, K.; Rotermund, F.; Park, K. H.; Marsal, L. F.; Pallarès, J.; Formentín, P.; Mateos, X.; Carvajal, J. J.; Pujol, M. C.; Galceran, M.


    We report the formation of two-dimensional disordered arrays of poly(methyl)methacrylate (PMMA) microcolumns with embedded single size distribution of Lu0.990Er0.520Yb0.490 nanocrystals, (Er,Yb):Lu2O3, using a disordered porous silicon template. The cubic (Er,Yb):Lu2O3 nanocrystals, which crystallize into the cubic system with Ia 3 ? space group, were synthesized using the modified Pechini method. Electronic microscopic techniques were used to study the distribution of the nanocrystals in the...

  16. Studies of upconversion emission of Yb3+, Er3+:Lu2O3 nanoceramics (United States)

    Gluchowski, P.; Strek, W.


    The translucent Yb3+ and Er3+ doped Lu2O3 ceramics composed of nanocrystalline grains were sintered using a low temperature and high pressure method. The upconversion emission associated with the 2H11/2 → 4I15/2, 4S3/2 → 4I15/2 (green), 4F9/2 → 4I15/2 (red) and 4I9/2 → 4I15/2 (IR) transitions was observed upon intense infrared laser excitation. The dependence of the upconversion intensity on incident laser diode power in Yb3+, Er3+:Lu2O3 nanoceramics was investigated. In particular it was found that the green/red intensity ratio of upconversion transitions increased with the power of the incident laser light. This effect was due to heating of the nanoceramics with increasing excitation power and may be utilized for high temperature thermometry.

  17. Lu3+/Yb3+ and Lu3+/Er3+ co-doped antimony selenide nanomaterials: synthesis, characterization, and electrical, thermoelectrical, and optical properties (United States)

    Hanifehpour, Younes; Joo, Sang Woo; Min, Bong-Ki


    Lu3+/Yb3+ and Lu3+/Er3+ co-doped Sb2Se3 nanomaterials were synthesized by co-reduction method in hydrothermal condition. Powder X-ray diffraction patterns indicate that the Ln x Ln' x Sb2-2 x Se3 Ln: Lu3+/Yb3+ and Lu3+/Er3+ crystals ( x = 0.00 - 0.04) are isostructural with Sb2Se3. The cell parameters were increased for compounds upon increasing the dopant content ( x). Scanning electron microscopy and transmission electron microscopy images show that co-doping of Lu3+/Yb3+ ions in the lattice of Sb2Se3 produces nanorods, while that in Lu3+/Er3+ produces nanoparticles, respectively. The electrical conductivity of co-doped Sb2Se3 is higher than that of the pure Sb2Se3 and increases with temperature. By increasing the concentration of Ln3+ions, the absorption spectrum of Sb2Se3 shows red shifts and some intensity changes. In addition to the characteristic red emission peaks of Sb2Se3, emission spectra of co-doped materials show other emission bands originating from f- f transitions of the Yb3+ ions.

  18. Magnetic structures in RNi₄B (R=Nd, Tb, Ho, Er)

    Energy Technology Data Exchange (ETDEWEB)

    Alleno, E., E-mail: [ICMPE, UMR 7182 CNRS-UPEC, 2 rue Henri Dunant, 94320 Thiais (France); Mazumdar, C. [Saha Institute of Nuclear Physics, Sector-1, Block-AF, 700064 Kolkata (India)


    Neutron diffraction has been performed on RNi₄B (R=Nd, Tb, Ho, Er) polycrystals. The orthorhombic structure for NdNi₄B and the CeCo₄B structure type (hexagonal) for TbNi₄B and HoNi₄B are confirmed. Our data also show that this last structure is currently the best approximant for ErNi₄B. The RNi₄B (R=Nd, Tb, Ho, Er) order ferromagnetically at respectively 11.0, 18.1, 6.2 and 10.0 K. The crystal electric field (CEF) interaction controls the magnetic anisotropy in this series leading to an easy axis ~30 deg above the basal plane in RNi₄B (R=Nd, Tb, Ho) and parallel to the c-axis in ErNi₄B at 1.6 K. The RNi₄B (R=Nd, Tb, Ho) display a spin re-orientation below Tc which arises from a competition between the second order term and the higher order terms of the CEF hamiltonian. - Graphical abstract: Simplified magnetic structure in NdNi₄B and full magnetic structure in RNi₄B (R=Tb, Ho). Variation with temperature of the easy magnetization axis direction (angle with c-axis) showing a spin re-orientation. Highlights: • RNi₄B (R=Nd, Tb, Ho, Er) polycrystals were inductively melted. • Neutron diffraction confirms they all order ferromagnetically. • The magnetization easy axis is parallel to the c-axis in ErNi₄B. • The RNi₄B (R=Nd, Tb, Ho) display a spin re-orientation below Tc. • Their easy axis tilts from the c-axis at Tc to ~30 deg above the basal plane at 1.5 K.

  19. Specific heat of Ho sub 2 Co sub 17 and Er sub 2 Co sub 17

    Energy Technology Data Exchange (ETDEWEB)

    Franse, J.J.M.; Klaasse, J.C.P.; Sinnema, S. (Amsterdam Univ. (NL). Natuurkunding Lab.); Radwanski, R.J. (University of Mining and Metallurgy, Krakow (PL). Solid State Physics Dept.)


    The specific heat of polycrystalline samples of Ho{sub 2}Co{sub 17} and Er{sub 2}Co{sub 17} has been measured between 1.25 K and 38 K in zero field and in an applied field of 5 T. The electronic, lattice, nuclear and crystal field contributions to the specific heat have been separated.

  20. The microscopic interaction parameters for Er{sup 3+}/Ho{sup 3+} energy transfer in tellurite glasses

    Energy Technology Data Exchange (ETDEWEB)

    Li Xujie [College of Computer Science and Engineering, Wenzhou University Zhejiang 325035 (China); Faculty of Information Science and Engineering, State Key Laboratory Base of Novel Functional Materials and Preparation Science, Ningbo University Zhejiang 315211 (China)], E-mail:; Zhang Wenjie [College of Computer Science and Engineering, Wenzhou University Zhejiang 325035 (China)


    We investigate the energy transfer between Er{sup 3+}/Ho{sup 3+} in tellurite glasses. The main channels of energy transfer between Er{sup 3+}/Ho{sup 3+} are analyzed in detail. The microscopic interaction parameters of resonant and non-resonant (phonon-assisted) energy transfer parameters via Er{sup 3+}{yields}Ho{sup 3+} are calculated. The result shows that the resonant energy transfers Er{sup 3+}({sup 2}H{sub 11/2}({sup 4}S{sub 3/2})){yields}Ho{sup 3+}({sup 5}F{sub 4}({sup 5}S{sub 2})) and Er{sup 3+}({sup 4}F{sub 9/2}){yields}Ho{sup 3+}({sup 5}F{sub 5}) are very efficient and non-resonant energy transfers Er{sup 3+}({sup 4}I{sub 13/2}){yields}Ho{sup 3+}({sup 5}I{sub 7}) and Er{sup 3+}({sup 4}I{sub 11/2}){yields}Ho{sup 3+}({sup 5}I{sub 6}), which are a phonon-assisted energy transfer process because of energy mismatch are also existed and cannot be neglected.

  1. Protectin DX suppresses hepatic gluconeogenesis through AMPK-HO-1-mediated inhibition of ER stress. (United States)

    Jung, Tae Woo; Kim, Hyung-Chun; Abd El-Aty, A M; Jeong, Ji Hoon


    Several studies have shown that protectins, which are ω-3 fatty acid-derived proresolution mediators, may improve insulin resistance. Recently, protectin DX (PDX) was documented to attenuate insulin resistance by stimulating IL-6 expression in skeletal muscle, thereby regulating hepatic gluconeogenesis. These findings made us investigate the direct effects of PDX on hepatic glucose metabolism in the context of diabetes. In the current study, we show that PDX regulates hepatic gluconeogenesis in a manner distinct from its indirect glucoregulatory activity via IL-6. We found that PDX stimulated AMP-activated protein kinase (AMPK) phosphorylation, thereby inducing heme oxygenase 1 (HO-1) expression. This induction blocked hepatic gluconeogenesis by suppressing endoplasmic reticulum (ER) stress in hepatocytes under hyperlipidemic conditions. These effects were significantly dampened by silencing AMPK or HO-1 expression with small interfering RNA (siRNA). We also demonstrated that administration of PDX to high fat diet (HFD)-fed mice resulted in increased hepatic AMPK phosphorylation and HO-1 expression, whereas hepatic ER stress was substantially attenuated. Furthermore, PDX treatment suppressed the expression of gluconeogenic genes, thereby decreasing blood glucose levels in HFD-fed mice. In conclusion, our findings suggest that PDX inhibits hepatic gluconeogenesis via AMPK-HO-1-dependent suppression of ER stress. Thus, PDX may be an effective therapeutic target for the treatment of insulin resistance and type 2 diabetes through the regulation of hepatic gluconeogenesis. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. In-band pumping of expitaxially grown Er:(Gd,Lu)2O3 waveguides for active integrated optical devices

    NARCIS (Netherlands)

    Kahn, A.; Kühn, H.; Heinrich, S.; Gün, T.; Tellkamp, F.; Petermann, K.; Bradley, J.; Ay, F.; Worhoff, Kerstin; Pollnau, Markus; Kuzminykh, Y.; Luo, Y.; Hoffmann, P.; Huber, G.

    Monocrystalline lattice matched Er(0.6%):(Gd, Lu)2O3 films with thicknesses up to 3 �?�m and nearly atomically flat surfaces have been deposited on Y2O3 substrates by Pulsed Laser Deposition (PLD). The epitaxial growth has been verified in-situ by Reflection High Energy Electron Diffraction (RHEED).

  3. Organ doses from hepatic radioembolization with 90Y, 153Sm, 166Ho and 177Lu: A Monte Carlo simulation study using Geant4 (United States)

    Hashikin, N. A. A.; Yeong, C. H.; Guatelli, S.; Abdullah, B. J. J.; Ng, K. H.; Malaroda, A.; Rosenfeld, A. B.; Perkins, A. C.


    90Y-radioembolization is a palliative treatment for liver cancer. 90Y decays via beta emission, making imaging difficult due to absence of gamma radiation. Since post-procedure imaging is crucial, several theranostic radionuclides have been explored as alternatives. However, exposures to gamma radiation throughout the treatment caused concern for the organs near the liver. Geant4 Monte Carlo simulation using MIRD Pamphlet 5 reference phantom was carried out. A spherical tumour with 4.3cm radius was modelled within the liver. 1.82GBq of 90Y sources were isotropically distributed within the tumour, with no extrahepatic shunting. The simulation was repeated with 153Sm, 166Ho and 177Lu. The estimated tumour doses for all radionuclides were 262.9Gy. Tumour dose equivalent to 1.82GBq 90Y can be achieved with 8.32, 5.83, and 4.44GBq for 153Sm, 166Ho and 177Lu, respectively. Normal liver doses by the other radionuclides were lower than 90Y, hence beneficial for normal tissue sparing. The organ doses from 153Sm and 177Lu were relatively higher due to higher gamma energy, but were still well below 1Gy. 166Ho, 177Lu and 153Sm offer useful gamma emission for post-procedure imaging. They show potential as 90Y substitutes, delivering comparable tumour doses, lower normal liver doses and other organs doses far below the tolerance limit.

  4. Electronic structure of R Sb (R =Y , Ce, Gd, Dy, Ho, Tm, Lu) studied by angle-resolved photoemission spectroscopy (United States)

    Wu, Yun; Lee, Yongbin; Kong, Tai; Mou, Daixiang; Jiang, Rui; Huang, Lunan; Bud'ko, S. L.; Canfield, P. C.; Kaminski, Adam


    We use high-resolution angle-resolved photoemission spectroscopy (ARPES) and electronic structure calculations to study the electronic properties of rare-earth monoantimonides RSb (R = Y, Ce, Gd, Dy, Ho, Tm, Lu). The experimentally measured Fermi surface (FS) of RSb consists of at least two concentric hole pockets at the Γ point and two intersecting electron pockets at the X point. These data agree relatively well with the electronic structure calculations. Detailed photon energy dependence measurements using both synchrotron and laser ARPES systems indicate that there is at least one Fermi surface sheet with strong three-dimensionality centered at the Γ point. Due to the "lanthanide contraction", the unit cell of different rare-earth monoantimonides shrinks when changing the rare-earth ion from CeSb to LuSb. This results in the differences in the chemical potentials in these compounds, which are demonstrated by both ARPES measurements and electronic structure calculations. Interestingly, in CeSb, the intersecting electron pockets at the X point seem to be touching the valence bands, forming a fourfold-degenerate Dirac-like feature. On the other hand, the remaining rare-earth monoantimonides show significant gaps between the upper and lower bands at the X point. Furthermore, similar to the previously reported results of LaBi, a Dirac-like structure was observed at the Γ point in YSb, CeSb, and GdSb, compounds showing relatively high magnetoresistance. This Dirac-like structure may contribute to the unusually large magnetoresistance in these compounds.

  5. Optical properties of NaLuF4: Yb3+: Tm3+/Ho3+ rare earth nanocrystals in microstructure hollow fiber (United States)

    Zhang, Yundong; Li, Hui; Li, Hanyang; Wu, Yongfeng; Yu, Changqiu; Zhang, Tuo; Yuan, Ping


    In the present paper, we first demonstrate NaLuF4: Yb3+: Tm3+/Ho3+ rare earth nanocrystals in microstructure hollow fiber. An analysis of the intense blue upconversion emission at 450 and 475 nm in Tm3+/Yb3+ codoped NaLuF4 under excitation power 0.65W available from solid laser emitting at 980nm, has been undertaken. Fluorescence intensity ratio (FIR) variation of temperature-sensitive blue upconversion emission at 450and 475 nm in this material was recorded in the temperature range from 300 to 345 K. The maximum sensitivity derived from the FIR technique of the blue upconversion emission is approximately 0.005 K-1. The results imply that Tm3+/Yb3+ codoped NaLuF4 is a potential candidate for the optical temperature sensor.

  6. Simulace RF přenosového kanálu pro DVB-T2


    Strouhal, Adam


    Diplomová práce se zabývá podrobnějším popisem systému DVB-T2. Popisuje jednotlivé modely RF přenosových kanálů pro fixní a mobilní příjem. Pro simulaci jejich vlivu na přenášený signál byla v prostředí MATLAB vytvořena aplikace s uživatelským prostředím, kde se nastavují parametry DVB-T2 a přenosového kanálu. Výsledky simulací jsou srovnány a vyhodnoceny s předchozím systémem DVB-T. This Master thesis is focused on detailed description of the DVB-T2 system. This work deals with the descri...

  7. Effective tuning of the ratio of red to green emission of Ho{sup 3+} ions in single LiLuF{sub 4} microparticle via codoping Ce{sup 3+} ions

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Wei, E-mail:; Dong, Jun; Liu, Jihong; Yan, Xuewen


    Yb{sup 3+}/Ho{sup 3+} codoped LiLuF{sub 4} microparticles have been successfully prepared via a facile hydrothermal method. The crystal phase and morphology of LiLuF{sub 4} microparticles were inspected by x-ray diffraction and scanning electron microscope, respectively. The upconversion emission of single LiLuF{sub 4}: Yb{sup 3+}/Ho{sup 3+} microparticle was carefully studied by a confocal microscopy setup under NIR 980 nm excitation. With the increase of Ce{sup 3+} ion concentrations of 12%, the ratio of red to green emission of the Ho{sup 3+} ions of single LiLuF{sub 4} microparticle was boosted about 17-fold, and the output colors were tuned from green to red, which is due to the two efficient cross-relaxation between Ho{sup 3+} and Ce{sup 3+} ions enhances the red and suppresses the green in the emission processes. To investigate the optical properties of the single microparticle or nanoparticle through the confocal microscopy setup can effectively avoid the influence of surrounding particle or environment, and could provide more precise information for better exploring the emission mechanisms of rare earth ions. The tunable upconversion emission of Ho{sup 3+} in single LiLuF{sub 4} microparticle in this work will have great potential applications in the micro optoelectronic devices and color display applications. - Highlights: • The optical properties of the single LiLuF4: Yb3+/Ho3+/Ce3+ microparticle were studied. • The output colors of single LiLuF4 microparticle were tuned from green to red. • The upconversion mechanisms between Ho3+ and Ce3+ ions were discussed based on emission spectrum.

  8. Synthesis and characterization of Ln,Yb:BaGdF5 (Ln = Er, Ho) nanocrystals by hydrothermal method (United States)

    Hu, Hongliang; Xiao, Liguang; Zhang, Xuejian


    The Er,Yb: BaGdF5 and Ho,Yb: BaGdF5 nanocrystal materials with the narrow particle size distribution was synthesized by a hydrothermal method at 180°C for 24 h. The phase structure and fluorescence properties were investigated by X-ray diffraction, scanning electron microscopy and up-conversion spectroscopy, respectively. The phase composition does not change with increasing the pH value, leading to the formation of a pure phase BaGdF5, while the solution was turbid state. The products show a good crystallinity, dispersion and uniform particle size distribution. Under the LD excitation at 980 nm, Er,Yb: BaGdF5 and Ho,Yb: BaGdF5 nanocrystal materials were researched in the visible range of the fluorescence spectrum. Er,Yb: BaGdF5 nanocrystals were achieved the launch of green, blue, and red. Ho,Yb: BaGdF5 nanocrystal with green and red light output were realized. The light-emitting belong to the two-photon transition process. And the possible mechanism for the corresponding up-conversion luminescence was also discussed. The Er,Yb: BaGdF5 and Ho,Yb: BaYbF5 nanocrystals with the narrow particle size distribution have potential applications in biological field as luminescence probes.

  9. High-field magnetization in Ho{sub 1-x}Er{sub x}Ga{sub 2} single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, A.V. [Permanent Magnets Laboratory, Ural State University, 620083, Ekaterinburg (Russian Federation); Baranov, N.V. [Permanent Magnets Laboratory, Ural State University, 620083, Ekaterinburg (Russian Federation); Markin, P.E. [Permanent Magnets Laboratory, Ural State University, 620083, Ekaterinburg (Russian Federation); Aruga Katori, H. [Institute for Solid State Physics, University of Tokyo, Roppongi 7-22-1, Tokoyo 106 (Japan); Goto, T. [Institute for Solid State Physics, University of Tokyo, Roppongi 7-22-1, Tokoyo 106 (Japan); Nakotte, H. [Van der Waals-Zeeman Laboratorium, Universiteit van Amsterdam, Valckenierstraat 65, 1018 XE, Amsterdam (Netherlands); Radwanski, R.J. [Center for Solid State Physics, Sw. Filip 5, 31-150, Krakow (Poland)]|[Institute for Physics and Informatics, Pedagogical University, 30-084, Krakow (Poland); Kim-Ngan, N.H. [Center for Solid State Physics, Sw. Filip 5, 31-150, Krakow (Poland)


    The hexagonal antiferromagnetic compounds HoGa{sub 2} and ErGa{sub 2} exhibit large anisotropy with two metamagnetic-like transitions in external magnetic fields applied along the easy direction: at 1.7 and 2.4 T along the a-axis for HoGa{sub 2}, and at 0.7 and 2.0 T along the c-axis for ErGa{sub 2}. Magnetization measurements in high fields up to 40 T have been performed on single crystals of the substituted compounds Ho{sub 1-x}Er{sub x}Ga{sub 2} (x=0, 0.2, 0.4 and 0.6). In HoGa{sub 2}, above the metamagnetic-transition fields, the a-axis magnetic moment increases slowly and reaches the value of 9.75{mu}{sub B} at 40 T, whereas along the c-axis it sharply rises but to a much lower value, of 7{mu}{sub B} only. In substituted compounds, besides the c-axis transition around 6 T, an additional transition appears at 18-19 T along the a-axis. The transition-field values were found to decrease slightly with increasing Er content for both transitions. ((orig.)).

  10. Elastic Properties of Ho0.5Er0.5 Single Crystal

    DEFF Research Database (Denmark)

    Spichkin, Yu.I.; Bohr, Jakob; Tishin, A.M.


    (3 kHz). The Young's modulus at 4.2 K was measured to be 154 GPa. From the obtained data the magnetic part of the Young's modulus and the Debye temperature theta-D=375 K were calculated. The anomalies on the Young's modulus and the interval friction temperature dependencies corresponding to magnetic......The results of an investigation of the Young's modulus E and the interval friction Q-1 of a Ho0.5Er0.5 single crystal in the basal plane in the temperature range 4.2-400 K are reported. The measurements were carried out by the method of flexural autovibrations of a thin sample with sound frequency...

  11. Fabrication of a novel nanocomposite Ag/graphene@SiO2-NaLuF4:Yb,Gd,Er for large enhancement upconversion luminescence. (United States)

    Yin, Dongguang; Cao, Xianzhang; Zhang, Lu; Tang, Jingxiu; Huang, Wenfeng; Han, Yanlin; Wu, Minghong


    Upconversion nanocrystals have a lot of advantages over other fluorescent materials. However, their applications are still limited due to their comparatively low upconversion luminescence (UCL). In the present study, a novel nanocomposite of Ag/graphene@SiO2-NaLuF4:Yb,Gd,Er for enhancing UCL was fabricated successfully, and its morphology, crystalline phase, composition, and fluorescent property were investigated. It is interesting to find that the Ag/graphene@SiO2-NaLuF4:Yb,Gd,Er and Ag@SiO2-NaLuF4:Yb,Gd,Er nanocomposites showed high UCL enhancements of 52- and 10-fold compared to the control of Ag-free nanocomposite SiO2-NaLuF4:Yb,Gd,Er, respectively. The enhancement of 52-fold is greater than those reported in our previous studies and some papers. Moreover, the measured life times of the Ag-presented nanocrystals were longer than that of Ag-absent counterparts. These enhancements of UCL can be ascribed to the effect of metal-enhanced fluorescence, which is caused by the enhancement of the local electric field. The UCL intensity of Ag/graphene@SiO2-NaLuF4:Yb,Gd,Er was 5.2-fold higher than that of Ag@SiO2-NaLuF4:Yb,Gd,Er, indicating that graphene presented in the fabricated nanocomposite structure favors metal-enhanced UCL. The small-sized Ag nanoparticles anchored on the graphene sheet mutually enhanced each other's polarizability and surface plasmon resonance, resulting in a big metal-enhanced UCL. This study provides a new strategy for effectively enhancing the UCL of upconversion nanocrystals. The enhancement potentially increases the overall upconversion nanocrystal detectability for highly sensitive biological, medical, and optical detections.


    African Journals Online (AJOL)


    MAARTEN LuTHER, die groot Hervormer, aan wie die Christenheid van alle lande so onuitspreeklik veel verskuldig is vir sy herontdek king en geesdriftige verkondiging van die Bybelse waarheid, het ook. 'n besondere betekenis ... Sien PROP. GEORG BERLtT, Martin Luther, Thom as Murner und das Kirchen- lied des 16.

  13. Infrared optical characterization and energy transfer of Na5Lu9F32 single crystals co-doped with Er3+/Tm3+ grown by Bridgman method (United States)

    Tang, Qingyang; Xia, Haiping; He, Shinan; Sheng, Qiguo; Chen, Baojiu


    This paper reported on successful preparation of Na5Lu9F32 single crystals co-doped with ∼2 mol% Er3+ and various Tm3+ concentrations from 0.7 mol% to 3.2 mol% by Bridgman method. The J-O intensity parameters of Er3+ were calculated and analyzed according to the absorption spectra. The fluorescence decay curve at Er3+:4I13/2 level was measured to investigate the luminescent properties of the Er3+/Tm3+ co-doped Na5Lu9F32, and the energy transfer process between Er3+ and Tm3+. An intense 2.7 μm emission was achieved with Tm3+ ions sensitizing Er3+ ions under the 800 nm LD pumping. The maximum emission intensity at 2.7 μm was obtained at about 3.2 mol% doping concentration of Tm3+ when the concentration of Er3+ ions was fixed at ∼2 mol% in the current research. The calculated maximum value of emission cross section at 2.7 μm was 2.22 × 10-20 cm2, and energy transfer efficiency from Er3+:4I13/2 to Tm3+:3F4 was 78%. The electric dipole-dipole interaction was dominant for the energy transfer from Er3+ to Tm3+ ions by using Inokuti-Hirayama's model.

  14. The normal and inverse magnetocaloric effect in RCu{sub 2} (R=Tb, Dy, Ho, Er) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, X.Q., E-mail: [School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083 (China); Xu, Z.Y. [National Institute of Metrology, Beijing 100029 (China); Zhang, B.; Hu, F.X. [State Key Laboratory for Magnetism, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China); Shen, B.G., E-mail: [State Key Laboratory for Magnetism, Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China)


    Orthorhombic polycrystalline RCu{sub 2} (R=Tb, Dy, Ho and Er) compounds were synthesized and the magnetic properties and magnetocaloric effect (MCE) were investigated in detail. All of the RCu{sub 2} compounds are antiferromagnetic (AFM) ordered. As temperature increases, RCu{sub 2} compounds undergo an AFM to AFM transition at T{sub t} and an AFM to paramagnetic (PM) transition at T{sub N}. Besides of the normal MCE around T{sub N}, large inverse MCE around T{sub t} was found in TbCu{sub 2} compound. Under a field change of 0–7 T, the maximal value of inverse MCE is even larger than the value of normal MCE around T{sub N} for TbCu{sub 2} compound. Considering of the normal and inverse MCE, TbCu{sub 2} shows the largest refrigerant capacity among the RCu{sub 2} (R=Tb, Dy, Ho and Er) compounds indicating its potential applications in low temperature multistage refrigeration. - Highlights: • Large inverse magnetocaloric effect is observed in TbCu{sub 2} compound. • The AFM to AFM transition is observed in RCu{sub 2} (R=Tb, Dy, Ho, Er) compounds. • The MCE performance of TbCu{sub 2} compound is evaluated in a more comprehensively way.

  15. Formation enthalpies of LaLn'O3 (Ln'=Ho, Er, Tm and Yb) interlanthanide perovskites (United States)

    Qi, Jianqi; Guo, Xiaofeng; Mielewczyk-Gryn, Aleksandra; Navrotsky, Alexandra


    High-temperature oxide melt solution calorimetry using 3Na2O·MoO3 at 802 °C was performed for interlanthanide perovskites LaLn'O3 (Ln'=Ho, Er, Tm and Yb) and lanthanide oxides (La2O3, Ho2O3, Er2O3, Tm2O3 and Yb2O3). The enthalpies of formation of these interlanthanide perovskites from binary lanthanide oxides at room temperature (25 °C) were determined to be -8.3±3.4 kJ/mol for LaHoO3, -9.9±3.0 kJ/mol for LaErO3, -10.8±2.7 kJ/mol for LaTmO3 and -12.3±2.9 kJ/mol for LaYbO3. There is a roughly linear relationships between these enthalpy values and the tolerance factor for these and for other LaM3+O3 (M=In, Sc, Ga, Al, Fe and Cr) perovskites, confirming that the distortion of the perovskites as results from ionic radius difference of A-site and B-site cations, is the main factor determining the stability of these compounds.

  16. Energy transfer between doubly doped Er3+, Tm3+and Ho3+ rare earth ions in SiO2 nanoparticles

    CSIR Research Space (South Africa)

    Dhlamini, MS


    Full Text Available ) colours were measured from both SiO2:Er3+,Tm3+ and SiO2:Ho3+,Tm3+ systems. The change in the intensities of the emission peaks in both the SiO2:Ho3+,Tm3+ and SiO2:Er3+,Tm3+ systems with the change in accelerating beam voltage is shown. Energy transfer from...

  17. Deactivation effects of the lowest excited state of Ho3+ at 2.9 μm emission introduced by Pr3+ ions in LiLuF4 crystal. (United States)

    Zhang, Peixiong; Hang, Yin; Zhang, LianHan


    The use of Pr3+ codoping for enhancement of the Ho3+:5I6 →5I7 mid-IR emissions were investigated in the LiLuF4 crystal for the first time. It was found that Pr3+ greatly increased Ho3+ 2.9 μm emission by depopulating the Ho3+:5I7 level while having little influence on the Ho3+:5I6 level, leading to greater population inversion. The energy transfer efficiency from Ho3+:5I7 to Pr3+:3F2 is calculated to be 88%. Based on Judd-Ofelt theory, the 2.9 μm emission cross section is calculated to be 1.91×10(-20)   cm2, and the gain property of the Ho3+:5I6 →5I7 transition is discussed. We propose that the Ho, Pr:LiLuF4 crystal may be a promising material for 2.9 μm laser applications.

  18. Přenos nízkofrekvenčního signálu po síti Ethernet v LabVIEW


    Khait, Ranny


    Hlavním tématem předkládané práce je přenos nízkofrekvenčního signálu po síti Ethernet v LabVIEW. Práce obsahuje teoretický úvod, ve kterém jsou popsány typy přenosových protokolů, metody komprese, Ethernet, popis programu LabVIEW a jeho použití a biosignály. Praktická část je zaměřená na realizaci odesílání a přijmu dat po síti Ethernet. The main topic of presented thesis is LabVIEW based audio signal transmision via Ethernet. This thesis contains theoretical part, in which are described ...

  19. Electronic structure and optical properties of the HoCoSi and ErNiSi compounds

    Energy Technology Data Exchange (ETDEWEB)

    Knyazev, Yu. V.; Lukoyanov, A. V., E-mail:; Kuz’min, Yu. I. [Russian Academy of Sciences, Institute of Metal Physics, Ural Branch (Russian Federation); Gupta, S.; Suresh, K. G. [Indian Institute of Technology, Department of Physics (India)


    The electronic structure and the optical properties of the HoCoSi and ErNiSi compounds are studied. Spin-polarized band calculations are performed in the local electron density approximation corrected for the strong electron–electron interactions in the 4f shell of a rare-earth ion (LSDA + U method [11]). The optical constants are measured by ellipsometry in a wide wavelength range, and the frequency dependences of a number of spectral parameters are determined. The calculated densities of states are used to interpret the structural features of the interband optical conductivities of the intermetallic compounds.

  20. Synthesis of NaLuF4:Er3+, Yb3+, Ce3+ nanoparticles and study of photoluminescent properties in C - band

    Directory of Open Access Journals (Sweden)

    Khaydukov K.V.


    Full Text Available The novel core@shell nanocrystals β-NaLuF4@NaLuF4 co-doped with rare-earth ions Er3+, Yb3+, Ce3+ have been synthesized. The nano-particles indicate the intensive lines of anti-Stokes luminescence in the telecommunication С - band of spectrum when pumped at 970-980 nm. The nanoparticles have been characterized by transmission electron microscopy and spectrofluorimetry. The nanoparticles have a size 40-80 nm and possess the intensive photo-luminescence 73 nm bandwidth centered around 1530 nm. The photo-luminescence kinetics of β-NaLuF4: Er3+/ Yb3+/ Ce3+ has been studied in IR range of spectrum. We have demonstrated that doping with cerium ions prevents serial stepwise excitation of erbium ions. Consequently, the lifetime of transition in erbium 4I13/2→4I15/2 has risen up to 6.9 ms. Intensity of 1530 nm line in Er3+ ions excited at 980 nm has been increased up to 6 times. Therefore, the nanoparticles are applicable to fabrication of compact waveguide amplifiers for C - band.

  1. Swift heavy ion irradiation effects on structural and magnetic characteristics of RFeO{sub 3} (R = Er, Ho and Y) crystals

    Energy Technology Data Exchange (ETDEWEB)

    Bhat, Monita [Crystal Growth and Materials Research Laboratory, Department of Physics and Electronics, University of Jammu, Jammu 180006 (India); Kaur, Balwinder [Crystal Growth and Materials Research Laboratory, Department of Physics and Electronics, University of Jammu, Jammu 180006 (India); Kumar, Ravi [Nuclear Science Centre, New Delhi 110067 (India); Joy, P.A. [National Chemical Laboratory, Pune (India); Kulkarni, S.D. [National Chemical Laboratory, Pune (India); Bamzai, K.K. [Crystal Growth and Materials Research Laboratory, Department of Physics and Electronics, University of Jammu, Jammu 180006 (India); Kotru, P.N. [Crystal Growth and Materials Research Laboratory, Department of Physics and Electronics, University of Jammu, Jammu 180006 (India)]. E-mail:; Wanklyn, B.M. [Department of Physics, Clarendon Laboratory, Oxford University, Oxford OX1 3PU (United Kingdom)


    Magnetic studies have been carried out on single crystals of RFeO{sub 3} (R Er, Ho and Y) using vibrating sample magnetometer before and after swift heavy ion irradiation. Highly anisotropic character of the crystals is maintained even after irradiation. Irradiation causes decrease in magnetization and increase in Neel temperature of the crystals studied. The decrease in magnetization is attributed to amorphization caused by irradiation. High-resolution X-ray diffraction studies confirm amorphization on irradiation of the RFeO{sub 3} (R = Er, Ho and Y) crystals.

  2. Mass attenuation coefficients for n-type InSe, InSe:Gd, InSe:Ho and InSe:Er single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Icelli, Orhan E-mail:; Erzeneoglu, Salih; Guerbulak, Bekir


    Measurements have been made to determine the mass attenuation coefficients of undoped n-type InSe, and Gd, Ho, Er doped n-InSe single crystals using a Si(Li) detector in the energy region 15.746-40.930 keV X-ray energies with energy dispersive X-ray fluorescence systems. InSe, InSe:Gd, InSe:Ho and InSe:Er single crystals were grown by using the stockbarger method. The measured values are graphically compared with the theoretical ones obtained using WinXcom.

  3. Výstavba a provoz sportovního areálu pro jízdu v terénu na MTB typu single trek.


    Novák, Jan


    Bakalářská práce se věnuje projektu výstavby sportovního areálu jízdy na horských kolech v terénu pro širokou veřejnost. První část práce se zabývá obecným rozdělením pohybových aktivit a jejím zdravotním přínosem. Dále se práce zabývá významem horské cyklistiky a novým trendem MTB cyklistiky single trek. V dalším kroku práce rozebírá podnikatelský záměr výstavby single trek a přínosem pro danou lokalitu. This bachelor's thesis deals project construction of mountain bikes facilities in ter...

  4. Spectroscopic evaluation of CaYA1O 4 doped with trivalent Er, Tm, Yb and Ho for eyesafe laser applications (United States)

    Hutchinson, J. Andrew; Verdun, Horacio R.; Chai, Bruce H. T.; Zandi, Bahram; Merkle, Larry D.


    Spectroscopic properties of relevance for laser applications have been studied for rare earths in CaYA1O 4. Fitting of a theoretical model to observed energy levels yields crystal field parameters and unobserved levels. Structural disorder leads to broad linewidths,but cross sections are larger than in many common hosts. Tm-Tm cross relaxation rates are comparable to those in Tm: YAG, and Yb-Er transfer rates are comparable to those in Yb, Er:phosphate glass. Room temperature Yb-Er upconversion is stronger than in YAG, but modeling shows that neither unconversion nor population of Er 4I {13}/{2} is very efficient upon pumping Yb. The host's yellow color intensifies upon annealing in air, a potential problem for visible laser operation. Tm or Ho 2 μm laser operation, or Er 1.5 μ operation upon direct excitation of Er 4I {13}/{2}, are more promising.

  5. Neutron scattering study on R{sub 2}PdSi{sub 3} (R=Ho,Er,Tm) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Fei


    Previous studies on the family of inter-metallic rare-earth compounds R{sub 2}PdSi{sub 3} revealed multifaceted magnetic properties, for instance, spin-glass like behavior. Experimental observations include: Signs of a crystallographic superstructure, complicated magnetic structures both in zero field and in applied magnetic fields as well as a generic phase in applied fields for compounds in the series with the heavy rare-earths R=Gd, Tb, Dy, Ho, Er and Tm. This thesis expands the studies on the magnetic properties of R{sub 2}PdSi{sub 3} employing mainly neutron scattering on single crystals with the focus on the compounds with R=Ho, Er and Tm. A detailed analysis of the crystallographic superstructure using modulation wave approach and group theory is presented. The resulting structure implies the existence of two different rare-earth sites with reduced symmetry and an arrangement of the different sites according to sequences as determined by the superstructure. It is shown that the reduced symmetry of the rare-earth sites is explicitly observed in the energy spectra of inelastic neutron scattering. The results on the magnetic structures and excitations are shown and discussed in the framework of the superstructure model. Specifically the generic phase in applied fields is interpreted as a direct consequence of the crystallographic superstructure. It is rather unusual that a crystallographic superstructure is playing such a decisive, and through the field dependence also tunable role in determining the magnetic properties as observed in R{sub 2}PdSi{sub 3}. The mediating interactions between the crystallographic part and the magnetic part of the system are discussed. (orig.)

  6. MgZn2-type {Ho, Er, Tm}FeGa rare earth compounds: Crystal structure and magnetic properties (United States)

    Morozkin, A. V.; Genchel, V. K.; Garshev, A. V.; Yapaskurt, V. O.; Nirmala, R.; Quezado, S.; Malik, S. K.


    The crystal structure of new hexagonal MgZn2-type {Ho, Tm}FeGa compounds (space group P63/mmc, N 194, hP12) has been established using powder X-ray diffraction studies. The magnetic properties of polycrystalline MgZn2-type ErFeGa compound have been studied using bulk magnetization data. ErFeGa exhibits ferromagnetic ordering at TC = 77 K and field sensitive antiferromagnetic-like ordering at Tm 58 K in field of 100 Oe and Tm 10 K in field of 5 kOe. The paramagnetic susceptibility follows Curie-Weiss law with effective paramagnetic moment per formula unit (Meff/fu) of 9.59 μB and paramagnetic Weiss temperature (ΘP) of 27 K. At 2 K, ErFeGa exhibits hard magnetic properties with remanent magnetization per formula unit (Mres/fu) of 3.7 μB, coercive field (Hcoer) of 8.2 kOe and critical field (Hcrit) of 9.6 kOe. The magnetocaloric effect of ErFeGa has been calculated in terms of isothermal magnetic entropy change (ΔSm) and maximum ΔSm values are -5.5 J/kg K for a field change of 0-50 kOe (relative cooling power RCP50 kOe 410 J/kg), -13.0 J/kg K for a field change of 0-140 kOe (RCP140 kOe 1230 J/kg) at 70 K and +1.7 J/kg K for a field change of 0-10 kOe at 10 K (RCP10 kOe 34 J/kg).

  7. Síntesis hidrotermal de monocristales LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho y Er

    Directory of Open Access Journals (Sweden)

    Señarís Rodríguez, M. A.


    Full Text Available Ten single crystals of the series LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er were synthesized by hydrothermal synthesis in a single step and without subsequent thermal treatments from aqueous solutions of metals salts at 240 ºC. The obtained single crystals have a size of various micrometers and their morphology changes throughout the serie: they are polygonal in the case of the compounds with Ln= Pr, Nd, Sm, Eu and Gd and needle-like in the case of the compounds with Ln= Y, Tb, Dy, Ho and Er. After the analysis of the obtained products employing different conditions of synthesis we attributed the different morphology to a greater growth rate along the c axis when the smaller ions (Y, Tb, Dy, Ho y Er are involved, due to their better adaptation to the compound’s crystal structure.Se han conseguido preparar monocristales de 10 óxidos mixtos de la serie LnMn2O5 (Ln= Y, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho y Er mediante síntesis hidrotermal optimizada, en un único paso y sin tratamientos térmicos posteriores partiendo de las correspondientes sales metálicas en disolución acuosa a 240 ºC. Los monocristales obtenidos son relativamente grandes, de varias micras y su morfología varía a lo largo de la serie: es poligonal en el caso de los compuestos de los lantánidos del inicio de la serie (Ln= Pr, Nd, Sm, Eu y Gd y acicular en el caso de los compuestos de Y y de los lantánidos del final de la serie (Ln= Tb, Dy, Ho y Er. Tras el análisis de los productos obtenidos empleando distintas condiciones de síntesis atribuimos la diferente morfología a una mayor velocidad de crecimiento cristalino a lo largo del eje c cuando intervienen los iones más pequeños (Y, Tb, Dy, Ho y Er debido a la mejor adaptación de éstos últimos a la estructura cristalina del compuesto.

  8. Effect of Rare Earth Elements (Er, Ho) on Semi-Metallic Materials (ScN) in an Applied Electric Field (United States)

    Kim, Hyunjung; Park, Yeonjoon; King, Glen C.; Lee, Kunik; Choi, Sang H.


    The development of materials and fabrication technology for field-controlled spectrally active optics is essential for applications such as membrane optics, filters for LIDARs, windows for sensors, telescopes, spectroscopes, cameras and flat-panel displays. The dopants of rare earth elements, in a host of optical systems, create a number of absorption and emission band structures and can easily be incorporated into many high quality crystalline and amorphous hosts. In wide band-gap semiconductors like ScN, the existing deep levels can capture or emit the mobile charges, and can be ionized with the loss or capture of the carriers which are the fundamental basis of concept for smart optic materials. The band gap shrinkage or splitting with dopants supports the possibility of this concept. In the present work, a semi-metallic material (ScN) was doped with rare earth elements (Er, Ho) and tested under an applied electric field to characterize spectral and refractive index shifts by either Stark or Zeeman Effect. These effects can be verified using the UV-Vis spectroscopy, the Hall Effect measurement and the ellipsometric spectroscopy. The optical band gaps of ScN doped with Er and doped with Ho were experimentally estimated as 2.33eV and 2.24eV ( 0.2eV) respectively. This is less than that of undoped ScN (2.5 0.2eV). The red-shifted absorption onset is a direct evidence for the decrease of band gap energy (Eg), and the broadening of valence band states is attributable to the doping cases. A decrease in refractive index with an applied field was observed as a small shift in absorption coefficient using a variable angle spectroscopic ellipsometer. In the presence of an electric field, mobile carriers are redistributed within the space charge region (SCR) to produce this electro-refractive effect. The shift in refractive index is also affected by the density and location of deep potential wells within the SCR. In addition, the microstructure change was observed by a TEM

  9. Vibrational, mechanical and thermodynamical properties of RE2Ti2O7 (RE = Sm, Gd, Dy, Ho, Er and Yb) pyrochlores (United States)

    Kushwaha, A. K.


    Vibrational, mechanical, thermodynamical properties and thermal conductivities of RE2Ti2O7 (RE = Sm, Gd, Dy, Ho, Er and Yb) pyrochlores have been calculated using a proposed eight-parameter bond-bending force constant model. The main outcome of present calculation is that the first neighbor interaction (Ti-O) is stronger than the second neighbor interactions (RE-O). This means that the bonding between Ti and O is more ionic than the one between RE and O. It is also found that the bond strength of RE-O and the bulk modulus decrease in the sequence Sm > Gd > Dy > Ho > Er > Yb. The bulk moduli and Young’s moduli of RE2Ti2O7 also decrease when RE changes from Sm to Yb.

  10. Solubility of La, Pr, Eu, Er and Lu in a media of 1M ionic force of NaCl by 303 K; Solubilidad de La, Pr, Eu, Er y Lu en medio de fuerza ionica 1M de NaCl, a 303 K

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez G, J.J.; Solache R, M.J.; Jimenez R, M.; Rojas H, A. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)


    The solubility and the solubility product of La, Pr, Eu, Er and Lu in media of 1M ionic force of NaCl by 303 K was determined, by means of a radiochemical method and the pLn{sup -}pCH diagrams in free conditions of CO{sub 2} were constructed. Moreover, the non saturation and the saturated zones and with them the pCH precipitation bound were determined. Finally a comparison among the obtained data in this work and those reported in the literature in several media was realized. (Author)

  11. Měření dechové frekvence z EKG signálu s ohledem na vyšetření aktivit autonomního nervového systému Measurement of breathing frequency from ECG in the examination of autonomous nervous system activities: Suggested methods and their verification


    Jakub Krejčí; Simona Gwozdziewiczová; Milan Elfmark; Šárka Theuerová; Pavel Stejskal; Petr Kolisko; Petr Štěpaník; Jiří Salinger


    Z celé řady metod měření dechové frekvence se autoři zaměřili na méně používanou metodu diagnostiky dechové frekvence, vycházející z hodnocení změn parametrů EKG signálu, které jsou způsobeny změnami objemu hrudníku v průběhu expiria a inspiria. Hlavním důvodem volby této metody byla skutečnost, že pro diagnostiku aktivity autonomního nervového systému (ANS) je monitor...

  12. Anti-Fibrotic Effect of Losartan, an Angiotensin II Receptor Blocker, Is Mediated through Inhibition of ER Stress via Up-Regulation of SIRT1, Followed by Induction of HO-1 and Thioredoxin. (United States)

    Kim, Hyosang; Baek, Chung Hee; Lee, Raymond Bok; Chang, Jai Won; Yang, Won Seok; Lee, Sang Koo


    Endoplasmic reticulum (ER) stress is increasingly identified as modulator of fibrosis. Losartan, an angiotensin II receptor blocker, has been widely used as the first choice of treatment in chronic renal diseases. We postulated that anti-fibrotic effect of losartan is mediated through inhibition of ER stress via SIRT1 (silent mating type information regulation 2 homolog 1) hemeoxygenase-1 (HO-1)/thioredoxin pathway. Renal tubular cells, tunicamycin (TM)-induced ER stress, and unilateral ureteral obstruction (UUO) mouse model were used. Expression of ER stress was assessed by Western blot analysis and immunohistochemical stain. ER stress was induced by chemical ER stress inducer, tunicamycin, and non-chemical inducers such as TGF-β, angiotensin II, high glucose, and albumin. Losartan suppressed the TM-induced ER stress, as shown by inhibition of TM-induced expression of GRP78 (glucose related protein 78) and p-eIF2α (phosphospecific-eukaryotic translation initiation factor-2α), through up-regulation of SIRT1 via HO-1 and thioredoxin. Losartan also suppressed the ER stress by non-chemical inducers. In both animal models, losartan reduced the tubular expression of GRP78, which were abolished by pretreatment with sirtinol (SIRT1 inhibitor). Sirtinol also blocked the inhibitory effect of losartan on the UUO-induced renal fibrosis. These findings provide new insights into renoprotective effects of losartan and suggest that SIRT1, HO-1, and thioredoxin may be potential pharmacological targets in kidney diseases under excessive ER stress condition.

  13. Magnetic Properties of Rare-Earth Aluminoborates RAl3(BO3)4 (R = Th, Er, OR Ho) at High Temperatures (United States)

    Kuvandikov, O. K.; Leonyuk, N. I.; Shakarov, Kh. O.; Shodiev, Z. M.; Amonov, B. U.


    A temperature dependence of the magnetic susceptibility [χ(T)] of rare-earth borates RAl3(BO3)4 (R = Tb, Er, or Ho) is measured by the Faraday method at temperatures in the interval 20-850°C. Nonlinear anomalies caused by structural transitions are observed in the dependences χ-1(T). It is established that the dependences χ-1(T) for each phase obey the linear Curie-Weiss law. The Curie temperatures and the magnetic moments corresponding to the chemical formula of the compounds have been found.

  14. Synthesis, Tunable Multicolor Output, and High Pure Red Upconversion Emission of Lanthanide-Doped Lu2O3 Nanosheets

    Directory of Open Access Journals (Sweden)

    Lingzhen Yin


    Full Text Available Yb3+ and Ln3+ (Ln = Er, Ho codoped Lu2O3 square nanocubic sheets were successfully synthesized via a facile hydrothermal method followed by a subsequent dehydration process. The crystal phase, morphology, and composition of hydroxide precursors and target oxides were characterized by X-ray diffraction (XRD, field emission scanning electron microscope (FE-SEM, and energy-dispersive X-ray spectroscope (EDS. Results present the as-prepared Lu2O3 crystallized in cubic phase, and the monodispersed square nanosheets were maintained both in hydroxide and oxides. Moreover, under 980 nm laser diode (LD excitation, multicolor output from red to yellow was realized by codoped different lanthanide ions in Lu2O3. It is noteworthy that high pure strong red upconversion emission with red to green ratio of 443.3 of Er-containing nanocrystals was obtained, which is beneficial for in vivo optical bioimaging.

  15. Enhanced 2.7- and 2.9-μm emissions in Er{sup 3+}/Ho{sup 3+} doped fluoride glasses sensitized by Pr{sup 3+} ions

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Ying, E-mail: [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310018 (China); Wei, Tao [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Jing, Xufeng [Institute of Optoelectronic Technology, China Jiliang University, Hangzhou 310018 (China); Zhang, Junjie [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310018 (China); Xu, Shiqing, E-mail: [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310018 (China)


    Highlights: • Enhanced 2.7 and 2.9 μm emissions were observed in fluoride glass. • Energy transfer mechanism among Er{sup 3+}, Ho{sup 3+} and Pr{sup 3+} was investigated. • High emission cross sections at 2.7- and 2.9-μm were obtained. - Abstract: In this report, Er{sup 3+}/Ho{sup 3+}/Pr{sup 3+} tri-doped fluoride glass was prepared. The enhancement of 2.7 and 2.9 μm emissions from Er{sup 3+}/Ho{sup 3+}doped system were achieved successfully after the addition of Pr{sup 3+}. The combination of low OH{sup −} concentration, low maximum phonon energy and high mid-infrared transmittance is beneficial to the realization of mid-infrared emissions. The energy transfer mechanism among Er{sup 3+}, Ho{sup 3+} and Pr{sup 3+} was investigated. The decay profiles of several levels were measured to further examine the enhanced mid-infrared emissions. Moreover, high stimulated emission cross sections at 2.7- and 2.9 μm (1.08 × 10{sup −20} cm{sup 2} and 2.0 × 10{sup −20} cm{sup 2}, respectively) were determined. Er{sup 3+}/Ho{sup 3+}/Pr{sup 3+} tri-doped fluoride glass might provide a new choice for mid-infrared laser.

  16. Formation of La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+}, and Lu{sup 3+} complexes with chloride ions, in aqueous medium; Formacion de complejos de La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+} y Lu{sup 3+} con iones cloruro, en medio acuoso

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez R, E.; Jimenez R, M.; Solache R, M. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico)


    The constants of stability of the complexes of La{sup 3+}, Pr{sup 3+}, Eu{sup 3+}, Er{sup 3+}, and Lu{sup 3+} with Cl{sup -} ions, its were determined, in the aqueous medium of HCI - HClO{sub 4} and by a solvent extraction method. The dinonyl naphtalene sulfonic acid in n-heptane was used as extractant. The lanthanides concentration, it was measured by a VIS spectrophotometry method and by another radiochemical. The ions specific interaction theory (SIT) it was used for the extrapolation to ionic force 0 M. The results indicate that the stability constants of the LnCI{sup 2+} species diminishes when increasing the ion force and the charge density. (Author)

  17. RE{sub 13}Pd{sub 25+x}Zn{sub 28-x} (RE = Y, Ho-Lu). A 4 x 4 x 4 tungsten superstructure with short Pd/Zn dumbbells as structural motif

    Energy Technology Data Exchange (ETDEWEB)

    Gerke, Birgit; Hoffmann, Rolf-Dieter; Niehaus, Oliver; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie


    The rare earth-based zinc compounds RE{sub 13}Pd{sub 25+x}Zn{sub 28-x} (RE = Y, Ho-Lu) were synthesized from the elements in sealed niobium ampoules with a maximum reaction temperature of 1470 K followed by different annealing sequences. The structures of all compounds were refined from single crystal X-ray diffraction data, indicating substantial Zn/Pd mixing on one 8c and one 24g zinc site. Exemplarily, the homogeneity range of the solid solution Yb{sub 13}Pd{sub 25+x}Zn{sub 28-x} was manifested from samples of different starting compositions and five single crystal data sets. The RE{sub 13}Pd{sub 25+x}Zn{sub 28-x} structures are cubic, space group I anti 43m with lattice parameters ranging from 1295 to 1307 pm, as a function of the rare earth element and the Zn/Pd mixing. Hierarchically, one can derive the RE{sub 13}Pd{sub 25+x}Zn{sub 28-x} structures from the simple bcc packing. A group-subgroup scheme was developed for this new 4 x 4 x 4 tungsten superstructure which shows vacancy ordering and dumbbell formation. Temperature dependent magnetic susceptibility measurements show diamagnetism for a Lu{sub 13}Pd{sub 29}Zn{sub 24} sample and Curie-Weiss paramagnetism for Tm{sub 13}Pd{sub 29}Zn{sub 24} down to 3 K.

  18. Heat capacity jumps induced by magnetic field in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet

    Energy Technology Data Exchange (ETDEWEB)

    Shevchenko, E.V. [Centre for Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Charnaya, E.V., E-mail: [Physics Department, St. Petersburg State University, St. Petersburg, 198504 (Russian Federation); Lee, M.K. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); NSC Instrument Center at NCKU, Tainan, 70101 Taiwan (China); Chang, L.J. [Department of Physics, National Cheng Kung University, Tainan, 70101 Taiwan (China); Khazanov, E.N.; Taranov, A.V. [Kotel' nikov Institute of Radio Engineering and Electronics RAS, 125009 (Russian Federation); Bugaev, A.S. [Moscow Institute of Physics and Technology, Moscow, 141700 (Russian Federation)


    Measurements of the heat capacity were carried out for the mixed Er{sub 2}HoAl{sub 5}O{sub 12} garnet at magnetic fields up to 15 T. The heat capacity variations at low temperatures were dominated by the Schottky anomalies. In addition, anomalous sharp steps in the heat capacity were observed in magnetic fields stronger than 8 T upon cooling as well as upon warming. The temperatures of the steps increased with increasing magnetic field. Jumps found upon cooling and warming were shifted relative to each other showing the thermal hysteresis. The sharp decrease in the heat capacity at low temperatures suggested the blocking of magnetic flips induced by strong enough magnetic fields. - Highlights: • Anomalous steps of the heat capacity were observed in the Er{sub 2}HoAl{sub 5}O{sub 12} garnet. • The steps are induced by magnetic field at low temperatures. • The temperatures of the steps increased with increasing magnetic field. • The steps show a pronounced thermal hysteresis. • The findings suggest the blocking of the magnetic moment flips at field.

  19. Thermal decomposition of Ln(C2H5CO2)3·H2O (Ln = Ho, Er, Tm and Yb)

    DEFF Research Database (Denmark)

    Grivel, Jean-Claude


    The thermal decomposition of Ho(III), Er(III), Tm(III) and Yb(III) propionate monohydrates in argon was studied by means of thermogravimetry (TG), differential thermal analysis (DTA), IR-spectroscopy and X-ray diffraction (XRD). Dehydration takes place around 90 °C. It is followed...... by the decomposition of the anhydrous propionates to Ln2O2CO3 (Ln = Ho, Er, Tm or Yb) with the evolution of CO2 and 3-pentanone (C2H5COC2H5) between 300 and 400 °C. The further decomposition of Ln2O2CO3 to the respective sesquioxides Ln2O3 is characterized by an intermediate plateau extending from approximately 500......–700 °C in the TG traces. This stage corresponds to an overall composition of Ln2O2.5(CO3)0.5 but is more probably a mixture of Ln2O2CO3 and Ln2O3. The stability of this intermediate state decreases for the lighter rare-earth (RE) compounds studied. Full conversion to Ln2O3 is achieved at about 1,100 °C...

  20. Informační systém skautského oddílu s využitím API webové galerie


    Vaněk, Petr


    V této práci je popsán návrh a realizace informačního systému skautského oddílu, který pro správu fotografií využívá aplikačně programové rozhraní. Systém uživatelům poskytuje zejména ucelenou správu komponent, příspěvků, akcí a fotografií. Jsou představeny vybrané služby pro správu alb a fotografií, které ve své specifikaci nabízejí využití jejich API. Vybranými službami jsou Picasa Web Albums, SkyDrive a Rajč Návrh aplikace zahrnuje celkovou architekturu systému a návrh databáze. Prác...

  1. The possibility of clinical application of the solid state lasers: Nd:YAG, Ho:YAG, and Er:YAG in otolaryngology - head and neck surgery (United States)

    Tomaszewska, M.; Kukwa, A.; Tulibacki, M.; Wójtowicz, P.; Olędzka, I.; Jeżewska, E.


    The purpose of this study was to summarize our experiences in clinical application of Nd:YAG, Ho:YAG and Er:YAG in otolaryngology- head and neck surgery. Choosing the laser type and parameters for the particular procedures was based on our previous research on tissue effects of those lasers. During the period of 1993-2006 we performed 3988 surgical procedures with the Nd:YAG laser. Over 87% of those were made for the nasal cavity pathologies as polyps, hyperplasia of inferior nasal turbinate, granulation tissue, postoperative adhesions, vascular malformations, under the local anesthesia conditions. In our experience Nd:YAG laser gives the possibility of good clinical control and low risk of side effects for disorders of high recurrence and frequent interventions necessity, as nasal polyps or respiratory papillomatosis. Nd:YAG assisted uvulopalatoplasty gives an interesting alternative for surgical procedures for snoring and slight/mild OSA-recognized patients. Due to its good hemostatic properties, it is a perfect tool for removal of the chemodectoma from meddle ear. During the period of 1995-2006 we performed 229 surgical procedures with the Ho:YAG laser, mostly for larynx pathologies (adhesion and scar tissue removal). In our experience Ho:YAG laser can serve as a precise laser knife for both soft and bony tissue. The ER:YAG laser still remain under clinical trial. Since 2001 year we performed 24 procedures of removing stone deposits from salivary glands. We believe it may become a promising method to cope with sialolithiasis which allows for glandule function preservation. All of the laser types mentioned above, can be easily coupled with endoscopes, what makes them available for all of the head and necklocalized disorders.

  2. Magnetostriction and thermal expansion of high T c magnetic superconductors REBa 2Cu 3O 7- x ( RE = Eu, Sm, Gd, Dy, Ho, Er, TmandY) Gd, Dy, Ho, Er, Tm and Y) (United States)

    Del Moral, A.; Ibarra, M. R.; Arnaudas, J. I.; Algarabel, P. A.; Marquina, C.; Morán, E.; Alario, M. A.


    Thermal expansion and magnetostriction measurements for REBa 2Cu 3O 7 -x superconductors are reported, up to 2.4 T and down to 3.8 K. Anisotropic striction is negligible, except for Dy and Ho compounds where is of single-ion origin. Volume striction displays similar order of magnitude and thermal variation, and it is weak (except for Dy compound) pointing to a "host" diamagnetic lattice origin.

  3. Magnetic properties of lithium rare-earth fluorides: Ferromagnetism in LiErF4 and LiHoF4 and crystal-field parameters at the rare-earth and Li sites

    DEFF Research Database (Denmark)

    Hansen, P. E.; Johansson, Torben; Nevald, Rolf


    Single crystals of LiErF4 and LiHoF4 have been grown and their magnetic properties measured from 1.3 K to 300 K. LiHoF4 turned out to be a nearly ideal Ising ferromagnet with TC=1.30±0.05 K and a saturation magnetization along the crystalline c axis of (6.98±0.02)μB. In LiErF4 no ordering...... was observed, but extrapolation indicates that below 0.5 K it will be ferromagnetic with the magnetic moments in the crytalline ab plane. From the susceptibilities the crystal-field parameters Bnm with (n, m)=(2, 0), (4, 0), (4, 4), (6, 0), (6, 4) have been extracted giving for Er3+ in LiErF4: 430., -985...

  4. Luminescence properties of Er3+/Nd3+ co-doped Na5Lu9F32 single crystals for 2.7 μm mid-infrared laser (United States)

    Tang, Qingyang; Xia, Haiping; Sheng, Qiguo; He, Shinan; Zhang, Jianli; Chen, Baojiu


    The enhanced 2.7 μm mid-infrared emission from the Er3+:4I11/2 → 4I13/2 transition with Nd3+ ions as the sensitizer was achieved in the Na5Lu9F32 single crystal which was successfully grown by a Bridgman method. The transmission spectrum was tested and almost no absorption of 2.7 μm band was observed. It was indicated that the content of OH- ion was very low in the crystal and it was beneficial to the 2.7 μm mid-infrared laser output. Intense 2.7 μm emissions were achieved with Nd3+ ions sensitizing Er3+ ions under the 800 nm LD pumping and the energy transfer processes between Er3+ and Nd3+ ions were analyzed. Meanwhile, the greatly decreased near infrared emission at 1.5 μm and green up-conversion emission were obtained. Additionally, the optimized concentration ratio of Er3+ to Nd3+ for efficient 2.7 μm emission was investigated in this work and the maximum emission cross section at 2.7 μm was calculated. The decay curve of 1.5 μm emission could be well fitted by Inokuti-Hirayama expression, which was strongly indicated the dipole-dipole energy transfer from Er3+ to Nd3+ ions. The results showed that Er3+/Nd3+ co-doped Na5Lu9F32 single crystal had potential applications in 2.7 μm mid-infrared laser.

  5. Crystal structure and chemistry of four new RBa{sub 4}Cu{sub 3}O{sub 8.5+{delta}} (R=Ho, Er, Tm and Yb) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Y.T.; Peterson, E.J.; Baldonado, P.S.; Coulter, J.Y.; Peterson, D.E.; Mueller, F.M. [Los Alamos National Lab., NM (United States). Materials Science and Technology Div.


    Four new RBa{sub 4}Cu{sub 3}O{sub 8.5+{delta}} (R143) compounds, where R=Ho, Er, Tm, and Yb, were synthesized from precursors Ho{sub 2}O{sub 3}, Er{sub 2}O{sub 3}, Tm{sub 2}O{sub 3}, Yb{sub 2}O{sub 3}, BaO{sub 2}, and CuO at 1000 C in an oxygen atmosphere. The oxygen stoichiometric value {delta} was found to be 0.50 for Ho143, 0.53 for Er143, 0.79 for Tm 143 and 1.01 for Yb143 by iodometric titration. Rietveld refinement of X-ray powder diffraction data showed that all the compounds belong to the space group Pm anti 3. The compounds have a cubic unit cell with lattice parameters of 8.09485{+-}0.00007 A for Ho143, 8.08236{+-}0.00005 A for Er143, 8.07670{+-}0.00008 A for Tm143, and 8.06198{+-}0.00005 A for Yb143. SQUID measurements indicated that none of the compounds was superconducting above 5 K. (orig.) 15 refs.

  6. 3d-4f exchange interactions in R sub 2 Ni sub 17. [Dy sub 2 Ni sub 17; Ho sub 2 Ni sub 17; Er sub 2 Ni sub 17

    Energy Technology Data Exchange (ETDEWEB)

    Marquina, C.; Kayzel, F.E.; Ahn, T.H.; Radwanski, R.J.; Franse, J.J.M. (Van der Waals-Zeeman Lab., Univ. van Amsterdam (Netherlands))


    Magnetization isotherms at 4.2 K in fields up to 38 T have been measured on free powder samples R{sub 2}Ni{sub 17} (R=Dy, Ho and Er). From the transition-field values the intersublattice molecular-field coefficient n{sub RT} and molecular field acting on the R moment have been derived. (orig.).

  7. 4f?4f absorption spectra and hypersensitivity in nine-coordinate Ho(III) and Er(III) complexes in different environments (United States)

    Khan, Azad A.; Hussain, H. A.; Iftikhar, K.


    The effect of change in the environment upon 4f-4f absorption spectra of nine-coordinate Ho(III) and Er(III) complexes with thiocyanate and 2,2'-bipyridyl in methanol, DMSO, DMF and pyridine have been investigated. The oscillator strength for hypersensitive and non-hypersensitive transitions have been calculated and variation in the intensity and band shape with respect to solvent type is rationalized in terms of solvent structure and coordinating properties. A comparison with 1,10-phenanthroline complexes is investigated and has been found that phen has a larger impact on the transition intensities for these ions. Pyridine has been found most effective in promoting 4f-4f intensity. The results indicate that it is important to consider both the static and dynamic coupling mechanism while analysing the oscillator strength of hypersensitive transition.

  8. Broadband mid-IR frequency comb with CdSiP2 and AgGaS2 from an Er,Tm:Ho fiber laser. (United States)

    Sánchez, D; Hemmer, M; Baudisch, M; Zawilski, K; Schunemann, P; Hoogland, H; Holzwarth, R; Biegert, J


    We report on the generation of a 2500 nm bandwidth frequency comb at 6.5 μm central wavelength based on critically phase-matched parametric down-conversion in the nonlinear crystal CdSiP(2) (CSP), driven by a compact Er,Tm:Ho fiber laser. The generated ultra-broadband pulses show a transform-limited duration of 2.3 optical cycles and carry up to 150 pJ of energy at a 100 MHz pulse repetition rate. For comparison, the spectrum generated in AgGaS(2) (AGS) spans from 6.2 to 7.4 μm at full-width at half-maximum (FWHM) with a pulse energy of 3 pJ. A full 3D nonlinear wave propagation code is used for optimization of the noncollinear angle, propagation direction, and crystal thickness.

  9. Structural and magnetic properties of two branches of the tripod-kagome-lattice family A2R3Sb3O14 (A = Mg, Zn; R = Pr, Nd, Gd, Tb, Dy, Ho, Er, Yb) (United States)

    Dun, Z. L.; Trinh, J.; Lee, M.; Choi, E. S.; Li, K.; Hu, Y. F.; Wang, Y. X.; Blanc, N.; Ramirez, A. P.; Zhou, H. D.


    We present a systematic study of the structural and magnetic properties of two branches of the rare-earth tripod-kagome-lattice (TKL) family A2R3Sb3O14 (A = Mg, Zn; R = Pr, Nd, Gd, Tb, Dy, Ho, Er, Yb; here, we use abbreviation A-R, as in MgPr for Mg2Pr3Sb3O14 ), which complements our previously reported work on MgDy, MgGd, and MgEr [Z. L. Dun et al., Phys. Rev. Lett. 116, 157201 (2016), 10.1103/PhysRevLett.116.157201]. The present susceptibility (χdc, χac) and specific-heat measurements reveal various magnetic ground states, including the nonmagnetic singlet state for MgPr, ZnPr; long-range orderings (LROs) for MgGd, ZnGd, MgNd, ZnNd, and MgYb; a long-range magnetic charge ordered state for MgDy, ZnDy, and potentially for MgHo; possible spin-glass states for ZnEr, ZnHo; the absence of spin ordering down to 80 mK for MgEr, MgTb, ZnTb, and ZnYb compounds. The ground states observed here bear both similarities as well as striking differences from the states found in the parent pyrochlore systems. In particular, while the TKLs display a greater tendency towards LRO, the lack of LRO in MgHo, MgTb, and ZnTb can be viewed from the standpoint of a balance among spin-spin interactions, anisotropies, and non-Kramers nature of single-ion state. While substituting Zn for Mg changes the chemical pressure, and subtly modifies the interaction energies for compounds with larger R ions, this substitution introduces structural disorder and modifies the ground states for compounds with smaller R ions (Ho, Er, Yb).

  10. Heterometallic trinuclear {CoLn(III)} (Ln = Gd, Tb, Ho and Er) complexes in a bent geometry. Field-induced single-ion magnetic behavior of the Er(III) and Tb(III) analogues. (United States)

    Goura, Joydeb; Brambleby, Jamie; Topping, Craig V; Goddard, Paul A; Suriya Narayanan, Ramakirushnan; Bar, Arun Kumar; Chandrasekhar, Vadapalli


    Through the use of a multi-site compartmental ligand, 2-methoxy-6-[{2-(2-hydroxyethylamino)ethylimino}methyl]phenol (LH3), the family of heterometallic, trinuclear complexes of the formula [CoLn(L)2(μ-O2CCH3)2(H2O)3]·NO3·xMeOH·yH2O has been expanded beyond Ln = Dy(III) to include Gd(III) (), Tb(III) (), Ho(III) () and Er(III) () for , and (x = 1; y = 1) and for (x = 0; y = 2). The metallic core of these complexes consists of a (Co(III)-Ln(III)-Co(III)) motif bridged in a bent geometry resulting in six-coordinated distorted Co(III) octahedra and nine-coordinated Ln(III) monocapped square-antiprisms. The magnetic characterization of these compounds reveals the erbium and terbium analogues to display a field induced single-ion magnetic behavior similar to the dysprosium analogue but at lower temperatures. The energy barrier for the reversal of the magnetization of the CoTb(III) analogue is Ueff ≥ 15.6(4) K, while for the CoEr(III) analogue Ueff ≥ 9.9(8) K. The magnetic properties are discussed in terms of distortions of the 4f electron cloud.

  11. Synthetic and spectroscopic studies of vanadate glaserites I: Upconversion studies of doubly co-doped (Er, Tm, or Ho):Yb:K{sub 3}Y(VO{sub 4}){sub 2}

    Energy Technology Data Exchange (ETDEWEB)

    Kimani, Martin M., E-mail:; Chen, Hongyu, E-mail:; McMillen, Colin D., E-mail:; Anker, Jeffery N., E-mail:; Kolis, Joseph W., E-mail:


    The synthesis and upconversion properties of trigonal glaserite-type K{sub 3}Y(VO{sub 4}){sub 2} co-doped with Er{sup 3+}/Yb{sup 3+}, Ho{sup 3+}/Yb{sup 3+}, or Tm{sup 3+}/Yb{sup 3+} were studied. Powder samples were synthesized by solid state reactions at 1000 °C for 48 h, while well-formed hexagonal single crystals of the same were grown hydrothermally using 10 M K{sub 2}CO{sub 3} at 560–650 °C. Infrared-to-visible upconversion by Er{sup 3+}/Yb{sup 3+}, Ho{sup 3+}/Yb{sup 3+}, or Tm{sup 3+}/Yb{sup 3+} codoped-K{sub 3}Y(VO{sub 4}){sub 2} glaserite powder and single crystals was observed, and the upconversion spectral properties were studied as a function of different Er{sup 3+}, Tm{sup 3+}, Ho{sup 3+}, and Yb{sup 3+} ion concentrations. The process is observed under 980 nm laser diode excitation and leads to strong green (552 nm) and red (659 nm) emission for Er{sup 3+}/Yb{sup 3+}, green (549 nm) and red (664 nm) emission for Ho{sup 3+}/Yb{sup 3+}, and blue (475 nm) and red (647 nm) emission for Tm{sup 3+}/Yb{sup 3+}. The main mechanism that allows for up-conversion is attributed the energy transfer among Yb{sup 3+} and the various Er{sup 3+}/Ho{sup 3+}/Tm{sup 3+} ions in excited states. These results illustrate the large potential of co-doped alkali double vanadates for photonic applications involving optoelectronics devices. - Graphical abstract: Synthesis and upconversion in vanadate glaserites. - Highlights: • K{sub 3}Y(VO{sub 4}){sub 2} codoped with Er, Tm, or Ho:Yb were synthesized via solid-state and hydrothermal routes. • Upconversion properties are investigated. • The codoped compounds revealed efficient infrared-to-visible upconversion. • The presented compounds are potential host for solid state lighting.

  12. Emission properties of hydrothermal Yb{sup 3+}, Er{sup 3+} and Yb{sup 3+}, Tm{sup 3+}-codoped Lu{sub 2}O{sub 3} nanorods: upconversion, cathodoluminescence and assessment of waveguide behavior

    Energy Technology Data Exchange (ETDEWEB)

    Barrera, Elixir William; Pujol, MarIa Cinta; DIaz, Francesc [Fisica i Cristal.lografia de Materials, Universitat Rovira i Virgili, Campus Sescelades c/ Marcel.lI Domingo s/n, E-43007 Tarragona (Spain); Choi, Soo Bong; Rotermund, Fabian [Division of Energy Systems Research, Ajou University, 443-749 Suwon (Korea, Republic of); Park, Kyung Ho [Korea Advanced Nano Fab Center, 443-270 Suwon (Korea, Republic of); Jeong, Mun Seok [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 500-712 Gwangju (Korea, Republic of); Cascales, Concepcion, E-mail: [Instituto de Ciencia de Materiales de Madrid, Consejo Superior de Investigaciones CientIficas, c/Sor Juana Ines de la Cruz, 3 Cantoblanco, E-28049 Madrid (Spain)


    Yb{sup 3+} and Ln{sup 3+} (Ln{sup 3+} = Er{sup 3+} or Tm{sup 3+}) codoped Lu{sub 2}O{sub 3} nanorods with cubic Ia3-bar symmetry have been prepared by low temperature hydrothermal procedures, and their luminescence properties and waveguide behavior analyzed by means of scanning near-field optical microscopy (SNOM). Room temperature upconversion (UC) under excitation at 980 nm and cathodoluminescence (CL) spectra were studied as a function of the Yb{sup +} concentration in the prepared nanorods. UC spectra revealed the strong development of Er{sup 3+4}F{sub 9/2} {yields} 4I{sub 15/2} (red) and Tm{sup 3+1}G{sub 4} {yields} {sup 3}H{sub 6} (blue) bands, which became the pre-eminent and even unique emissions for corresponding nanorods with the higher Yb{sup 3+} concentration. Favored by the presence of large phonons in current nanorods, UC mechanisms that privilege the population of {sup 4}F{sub 9/2} and {sup 1}G{sub 4} emitting levels through phonon-assisted energy transfer and non-radiative relaxations account for these observed UC luminescence features. CL spectra show much more moderate development of the intensity ratio between the Er{sup 3+4}F{sub 9/2} {yields}{sup 4}I{sub 15/2} (red) and {sup 2}H{sub 11/2}, {sup 4}S{sub 3/2} {yields} {sup 4}I{sub 15/2} (green) emissions with the increase in the Yb{sup 3+} content, while for Yb{sup 3+}, Tm{sup 3+}-codoped Lu{sub 2}O{sub 3} nanorods the dominant CL emission is Tm{sup 3+1}D{sub 2} {yields} {sup 3}F{sub 4} (deep-blue). Uniform light emission along Yb{sup 3+}, Er{sup 3+}-codoped Lu{sub 2}O{sub 3} rods has been observed by using SNOM photoluminescence images; however, the rods seem to be too thin for propagation of light.

  13. Návrh prototypovéholu s využitím technologií reverzního inženýrství a rapid prototyping


    Luňák, Václav


    Bakalářská práce je zaměřena na postup výroby součásti blinkru pro motocykl s využitím technologií reverzního inženýrství a Rapid Prototyping. Práce obsahuje stručný popis dostupných metod těchto technologií. V následujících částech se práce zabývá návrhem součásti a přípravou pro odlévání. Výroba součásti se provádí metodou FDM. Následně probíhá kontrola součásti 3D skenerem ATOS. Součást se porovná s původním návrhem součásti. Pro součást se vyrobí silikonová forma. Forma slouží pro odléván...

  14. Měření dechové frekvence z EKG signálu s ohledem na vyšetření aktivit autonomního nervového systému Measurement of breathing frequency from ECG in the examination of autonomous nervous system activities: Suggested methods and their verification

    Directory of Open Access Journals (Sweden)

    Jakub Krejčí


    Full Text Available Z celé řady metod měření dechové frekvence se autoři zaměřili na méně používanou metodu diagnostiky dechové frekvence, vycházející z hodnocení změn parametrů EKG signálu, které jsou způsobeny změnami objemu hrudníku v průběhu expiria a inspiria. Hlavním důvodem volby této metody byla skutečnost, že pro diagnostiku aktivity autonomního nervového systému (ANS je monitorován EKG signál, který je tak k dispozici i pro diagnostiku dechové frekvence. Pro návrh optimální metody měření dechové frekvence byly změny parametrů EKG signálu analyzovány metodou spektrální analýzy variability srdeční frekvence (BFrr, metodou spektrální analýzy variability amplitud QRS komplexů (BFqrs a časovou analýzou periodicity změn amplitud QRS komplexů (BFv. Monitorování EKG signálu a výpočet parametrů EKG signálu, včetně uvedených analýz, bylo provedeno systémem VarCor PF6 s modifikovaným programovým vybavením. Statistické ověření zvolených metod a doporučení optimální metody měření dechové frekvence bylo provedeno pomocí referenčních hodnot dechových frekvencí 9 a 12 dechů/min, které prostřednictvím akustických signálů byly předávány probandům. Charakteristika souboru: 55 mužů a žen ve věku 22,7 ± 2,4 roků, měření bylo provedeno v polohách leh 1 – stoj – leh 2, celková velikost statisticky zpracovávaného souboru byla n = 118. Ze statistických výsledků, kde byla testována pomocí t-testu významnost rozdílů průměrných hodnot vzhledem k referenčním hodnotám a dále z výpočtu hodnot absolutních rozdílů dechové frekvence byla doporučena metoda BFqrs umožňující diagnostiku dechové frekvence v rozsahu 6 až 25 dechů/min. Navržená metoda bude aplikována do stávajícího algoritmu diagnostického systému VarCor PF6, čímž se významně zpřesní interpretace výsledků vyšetření ANS. From a wide range of methods

  15. Crystal electric field splitting of R{sup 3+}-ions in pure and Co- and Cu-doped RNi{sub 2}B{sub 2}C (R=Ho, Er, Tm)

    Energy Technology Data Exchange (ETDEWEB)

    Gasser, U.; Allenspach, P.; Henggeler, W.; Zolliker, M.; Furrer, A. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    From the crystal-electric-field (CEF) splitting of the R{sup 3+}-ions, the CEF parameters of RNi{sub 2}B{sub 2}C (R=Ho, Er, Tm) were deduced. In order to get information about the influence of the variation of the density of states (DOS) at the Fermi level (E{sub F}), CEF spectroscopy measurements with Co- and Cu-doped ErNi{sub 2}B{sub 2}C-samples were performed. (author) 1 fig., 1 tab., 1 ref.

  16. Synthetic and spectroscopic studies of vanadate glaserites II: Photoluminescence studies of Ln:K{sub 3}Y(VO{sub 4}){sub 2} (Ln=Eu, Er, Sm, Ho, or Tm)

    Energy Technology Data Exchange (ETDEWEB)

    Kimani, Martin M., E-mail:; McMillen, Colin D., E-mail:; Kolis, Joseph W., E-mail:


    Glaserite-type potassium yttrium double vanadates (K{sub 3}Y(VO{sub 4}){sub 2}) doped with Eu{sup 3+}, Er{sup 3+}, Sm{sup 3+}, Ho{sup 3+}, or Tm{sup 3+} have been synthesized by solid state reactions at 1000 °C for 48 h and their photoluminescence properties investigated. Efficient energy transfer from the vanadate group to the rare earth ion has been established by photoluminescence investigation. Ultraviolet excitation into the metal to ligand charge transfer band of the vanadate groups results in orange-red, blue and green emissions from Eu{sup 3+} (592 nm), Sm{sup 3+} (602 nm), Tm{sup 3+} (475 nm), Er{sup 3+} (553 nm), and Ho{sup 3+} (541–551 nm) dopant ions. The emission intensities of the lanthanide-doped K{sub 3}Y(VO{sub 4}){sub 2} powders were studied as a function of dopant ion concentrations. Over the concentration ranges studied, no emission quenching was observed for Eu{sup 3+} or Ho{sup 3+} dopants, while Er{sup 3+}, Sm{sup 3+} and Tm{sup 3+} dopants did exhibit such effects for dopant ion concentrations greater than 5%, probably due to cross relaxation processes. - Graphical abstract: Synthesis and photoluminescence in vanadate glaserites. - Highlights: • K{sub 3}Y(VO{sub 4}){sub 2} doped with Eu, Er, Tm, Sm, or Ho were synthesized via solid-state reactions. • Photoluminescence properties are investigated. • The lanthanide doped K{sub 3}Y(VO{sub 4}){sub 2} compounds revealed efficient energy transfer from the vanadate group to the rare earth ions. • The presented compounds are promising materials for light display systems, lasers, and optoelectronic devices.

  17. Sub-10 nm Sr2LuF7:Yb/Er@Sr2GdF7@SrF2 Up-Conversion Nanocrystals for Up-Conversion Luminescence-Magnetic Resonance-Computed Tomography Trimodal Bioimaging. (United States)

    Chen, Cailing; Liu, Jianhua; Chen, Ying; Li, Chunguang; Liu, Xiaomin; Huang, He; Liang, Chen; Lou, Yue; Shi, Zhan; Feng, Shouhua


    Herein, sub-10 nm core-shell nanocrystals (NCs), which select Sr2LuF7:Yb/Er as core, Sr2GdF7 as middle shell, and SrF2 as an outermost shell, were synthesized by a seed-mediated growth process. The NCs possess good crystallinity, morphology, and up-conversion luminescent properties. After modification by polyethylenimine branched (PEI), in vitro cell up-conversion imaging with low autofluorescence was realized. Due to the presence of Gd(3+) ions, in vivo magnetic resonance (MR) imaging was also achieved with these designed NCs. More significantly, these special core-shell NCs exhibited high contrast in in vivo X-ray computed tomography (CT) imaging because of their good X-ray absorption ability. These results indicate that the core-shell up-conversion NCs can serve as promising contrast agents for up-conversion luminescence-MR-CT trimodal bioimaging.

  18. Bonding Strength of Ceromer with Direct Laser Sintered, Ni-Cr-Based, and ZrO2 Metal Infrastructures After Er:YAG, Nd:YAG, and Ho:YAG Laser Surface Treatments-A Comparative In Vitro Study. (United States)

    Gorler, Oguzhan; Ozdemir, Ali Kemal


    Laser modalities instead of conventional surface treatment techniques have been suggested to obtain an adequate micromechanical bonding between dental super- and infrastructures. The present study was undertaken to assess the effect of surface treatment with Ho:YAG, Er:YAG, and Nd:YAG laser modalities on the shear bond strength (SBS) of ceromer to different types of metal infrastructures in in vitro settings. The study specimens consisted of 40 direct laser sintered (DLS), 40 Ni-Cr-based, and 40 zirconium oxide (ZrO2) infrastructures. In each infrastructure group, the specimens were divided randomly into five treatment modalities (n = 8): no treatment (controls), sandblasting, Er:YAG, Nd:YAG, and Ho:YAG lasers. The DLS, Ni-Cr-based, and ZrO2 infrastructures were prepared in the final dimensions of 7 mm in diameter and 3 mm in thickness in line with the ISO 11405 standard. Ceromer as superstructure was applied to all the infrastructures after their surface treatments according to the selected treatment modality. SBS test was performed to test the effectiveness of surface treatments. A stereomicroscope was used to determine the changes in the surface morphology of specimens. Among the laser modalities and sandblasting, Ho:YAG laser caused the most important increase in the DLS and Ni-Cr-based infrastructures but sandblasting caused the most important increase in the ZrO2 infrastructure. In all the infrastructures, Nd:YAG laser has the least effectiveness, and Er:YAG laser makes an intermediate success. The stereomicroscopy images presented that the applications of laser surface treatments altered the surface in all the infrastructures. Overall, in current experimental settings, Ho:YAG, Nd:YAG, and Er:YAG lasers, in order of strength, are effective in improving the bonding of ceromer to all the infrastructures. Ho:YAG laser is more effective in the DLS and Ni-Cr-based infrastructures, but sandblasting is more effective in the ZrO2 infrastructure. The studied

  19. Carboxylate-bridged copper(II)-lanthanide(III) complexes [(Cu(3)Ln(2)(oda)(6)(H(2)O)(6)).12H(2)O](n)(Ln = Dy, Ho, Er, Y; oda = oxydiacetate). (United States)

    Rizzi, Alberto C; Calvo, Rafael; Baggio, Ricardo; Garland, María Teresa; Peña, Octavio; Perec, Mireille


    The hydrothermal reaction of Ln(2)O(3) (Ln = Dy and Ho), Cu(OAc)(2).2H(2)O, and oxydiacetic acid in the approximate mole ratio of 1:3:8 resulted in the formation of two new members of the isostructural series of polymers formulated as [(Cu(3)Ln(2)(oda)(6)(H(2)O)(6)).12H(2)O](n), crystallizing in the hexagonal crystal system, space group P6/mcc (No. 192). Temperature-dependent magnetic susceptibilities and EPR spectra are reported for the heterometallic compounds Cu-Dy 1, Cu-Ho 2, Cu-Er 3, and Cu-Y 4. The results are discussed in terms of the structure of the compounds, the electronic properties of the lanthanide ions, and the exchange interactions between the magnetic ions.

  20. Crystal structure, magnetic and electrical properties of compounds in the RCrMnO{sub 5} family (R = Sm, Eu, Gd, Tb, Ho and Er) synthesized under high oxygen pressure

    Energy Technology Data Exchange (ETDEWEB)

    Pomiro, Fernando; Miner, Elisa V.P.; Carbonio, Raul E. [INFIQC (CONICET - Universidad Nacional de Cordoba), Departamento de Fisicoquimica, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba (Argentina); Lohr, Javier; Sanchez, Rodolfo D. [Centro Atomico Bariloche, Comision Nacional de Energia Atomica and Instituto Balseiro, Universidad Nacional de Cuyo, San Carlos de Bariloche (Argentina); Nassif, Vivian [Institut Neel, CNRS et Universite Joseph Fourier, Grenoble (France)


    RCrMnO{sub 5} (R = Sm, Eu, Gd, Tb, Ho, and Er) were synthesized at high O{sub 2} pressures and 900-950 C. Crystal structures were refined by using powder X-ray diffraction (PXRD) and powder neutron diffraction (PND) for Tb, Ho, and Er compounds and PXRD for Sm, Eu and Gd compounds. All compounds were isostructural with RMn{sub 2}O{sub 5}. By using the bond-valence model we found that (Cr/Mn){sup 4+} mainly occupy the octahedral sites and (Cr/Mn){sup 3+} occupy the pyramidal sites. Antisite disorder between octahedral and pyramidal sites was found in the three samples analyzed by PND. From the values obtained for the occupancies of Cr and Mn in the pyramidal and octahedral sites and from the approximate average oxidation states for each crystallographic site obtained by the bond-valence calculations, an estimated ionic distribution model was proposed. The μ{sub eff} value for RCrMnO{sub 5} could be explained by considering the contribution of all the paramagnetic species and by using the ionic distribution model. No magnetic long-range order was observed by PND in R = Er, Ho, and Tb compounds. All the Curie-Weiss temperatures obtained from the magnetic susceptibility were negative (θ < 0), indicating antiferromagnetic correlations. For the compounds with Eu and Sm, θ close to -200 K were obtained for the Cr-Mn sublattice. The semiconducting properties could be described by a variable range hopping mechanism associated with antisite disorder of Cr/Mn. No dielectric transitions were observed in the electric permittivity in the measured temperature range. (Copyright copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  1. Indium flux synthesis of RE4Ni2InGe4 (RE = Dy, Ho, Er, and Tm): an ordered quaternary variation on the binary phase Mg5Si6. (United States)

    Salvador, James R; Kanatzidis, Mercouri G


    The quaternary compounds RE4Ni2InGe4 (RE = Dy, Ho, Er, and Tm) were obtained as large single crystals in high yields from reactions run in liquid In. The title compounds crystallize in the monoclinic C2/m space group with the Mg(5)Si(6) structure type with lattice parameters a = 15.420(2) A, b = 4.2224(7) A, c = 7.0191(11) A, and beta = 108.589(2) degrees for Dy4Ni2InGe4, a = 15.373(4) A, b = 4.2101(9) A, c = 6.9935(15) A, and beta = 108.600(3) degrees for Ho4Ni2InGe4, a = 15.334(7) A, b = 4.1937(19) A, c = 6.975(3) A, and beta =108.472(7) degrees for Er4Ni2InGe4, and a = 15.253(2) A, b = 4.1747(6) A, c = 6.9460(9) A, and beta = 108.535(2) degrees for Tm4Ni2InGe4. RE4Ni2InGe4 formed in liquid In from a melt that was rich in the rare-earth component. These compounds are polar intermetallic phases with a cationic rare-earth substructure embedded in a transition metal and main group matrix. The rare-earth atoms form a highly condensed network, leading to interatomic distances that are similar to those found in the elemental lanthanides themselves. The Dy and Ho analogues display two maxima in the susceptibility, suggesting antiferromagnetic ordering behavior and an accompanying spin reorientation. The Er analogue shows only one maximum in the susceptibility, and no magnetic ordering was observed for the Tm compound down to 2 K.

  2. Magnetic ordering in the rare earth iron germanates HoFeGesub>2sub>O>7sub> and ErFeGesub>2sub>O>7sub>

    DEFF Research Database (Denmark)

    Cascales, C.; Puebla, E.G.; Klimin, S.


    RFeGe2O7 (R = Ho, Er) have been prepared in polycrystalline form, and their crystal structures have been refined from room-temperature high-resolution neutron diffraction data by the Rietveld method. Both materials are isostructural, space group P2(1)/m (no. 11), Z = 4. The most interesting feature....... The propagation vector of the magnetic structure is k = [0, 0, 0]. In each case the magnetic structure consists of a ferromagnetic arrangement of all R3+ and Fe3+ magnetic moments within one ac plane, whereas the corresponding moments in up and down adjacent planes are oppositely aligned, leading to 3D AF...

  3. Hydrogenation Properties of Laves Phases LnMg2 (Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Ho, Er, Tm, Yb). (United States)

    Werwein, Anton; Maaß, Florian; Dorsch, Leonhard Y; Janka, Oliver; Pöttgen, Rainer; Hansen, Thomas C; Kimpton, Justin; Kohlmann, Holger


    The hydrogenation properties of Laves phases LnMg2 (Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Ho, Er, Tm, Yb) were investigated by thermal analysis, X-ray, synchrotron, and neutron powder diffraction. At 14.0 MPa hydrogen gas pressure and 393 K, PrMg2 and NdMg2 take up hydrogen and form the colorless, ternary hydrides PrMg2H7 (P41212, a = 632.386(6) pm, c = 945.722(11) pm) and NdMg2H7 (P41212, a = 630.354(9) pm, c = 943.018(16) pm). The crystal structures were refined by the Rietveld method from neutron powder diffraction data on the deuterides (PrMg2D7, P41212, a = 630.56(2) pm, c = 943.27(3) pm; NdMg2D7, P41212, a = 628.15(2) pm, c = 940.32(3) pm) and shown to be isotypic to LaMg2D7. The LaMg2D7 type of hydrides decompose at 695 K (La), 684 K (Ce), 684 K (Pr), 672 K (Nd), and 639 K (Sm) to lanthanide hydrides and magnesium. The Laves phase EuMg2 forms a hydride EuMg2Hx of black color. Its crystal structure (P212121, a = 664.887(4) pm, b = 1136.993(7) pm, c = 1069.887(7) pm) is closely related to the hexagonal Laves phase (MgZn2 type) of the hydrogen-free parent intermetallic. GdMg2 and TbMg2 form hydrides GdMg2Hx with orthorhombic unit cells (a = 1282.7(4) pm, b = 572.5(2) pm, c = 881.7(2) pm) and TbMg2Hx (a = 617.8(3) pm, b = 1045.8(8) pm, c = 997.1(5) pm), presumably also with a distorted MgZn2 type of structure. CeMg2H7 and NdMg2H7 are paramagnetic with effective magnetic moments of 2.49(1) μB and 3.62(1) μB, respectively, in good agreement with the calculated magnetic moments of the free trivalent rare-earth cations (μcalc(Ce3+) = 2.54 μB; μcalc(Nd3+) = 3.62 μB).

  4. Symmetry-Breaking Transitions in RECuAs2-xPx (RE=Sm, Gd, Ho, and Er)

    Energy Technology Data Exchange (ETDEWEB)

    Mozharivskyj, Yurij [Iowa State Univ., Ames, IA (United States)


    Structural changes resulting in lower symmetries can be understood in terms of electronic instabilities and Coulomb interactions. The interplay of these two interrelated factors is complicated and difficult to analyze. The RECuAs2-xP x phases, because of the variation in the chemical content (As/P substitution), allow, with the aid of band structures, Madelung energies and Landau theory, a partial unraveling of the forces important in the symmetry-breaking transitions in RECuAs2-xP x (RE = Sm, Gd, Ho and Er). Distortions of the P layers in SmCu1.15P2, GdCuP2.20 and ErCuP2 are usefully thought of as generalized Peierls distortions, i.e., they lower the electronic (and total) energy and lead to more stable structures. On the other hand, the P4/nmm → Pmmn transitions, which are observed in all studied arsenophosphide series and occur upon substitution of P for As, originate from the B1g vibrational mode and are structural adaptations to smaller P atoms. These transitions provide tighter atomic packing and better Coulomb interactions. Configurational contribution to the entropy becomes important in stabilizing the mixed occupancy in the RECuAs 2-xP x arsenophosphides. While geometric and electronic factors favor separation of the As and P atoms over two different crystallographic sites, configurational entropy stabilizes the As/P mixing on these two sites.;Progress in the research on RECuAs2-xP x was dependent upon the ability of Landau theory to predict, explain and dismiss structural models and transitions. The space group Pmmn (arising from the B 1g vibrational mode) in all mixed arsenophosphides and the existence of these mixed arsenophosphides followed from the analysis of GdCuAs 2 and GdCuP2, using Landau theory. The impossibility of obtaining the high-symmetry structure (P4/nmm) and the low symmetry structure

  5. Magnetic properties and magnetocaloric effect in the RCu{sub 2}Si{sub 2} and RCu{sub 2}Ge{sub 2} (R = Ho, Er) compounds

    Energy Technology Data Exchange (ETDEWEB)

    Mo, Zhao-Jun [School of Material Science and Engineering, Hebei University of Technology, Tianjin (China); Key laboratory of cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing (China); Shen, Jun, E-mail:, E-mail:; Wu, Jian-Feng [Key laboratory of cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing (China); Yan, Li-Qin; Wang, Li-Chen; Sun, Ji-rong; Shen, Bao-Gen [State Key Laboratory of Magnetism, Beijing National Laboratory for Condensed Matter, Physics and Institute of Physics, Chinese Academy of Sciences, Beijing (China); Gao, Xin-Qiang; Tang, Cheng-Chun, E-mail:, E-mail: [School of Material Science and Engineering, Hebei University of Technology, Tianjin (China)


    The magnetic properties and magnetocaloric effect (MCE) in RCu{sub 2}Si{sub 2} and RCu{sub 2}Ge{sub 2} (R = Ho, Er) compounds have been investigated. All these compounds possess an antiferromagnetic (AFM)-paramagnetic (PM) transition around their respective Neel temperatures. The RCu{sub 2}Si{sub 2} compounds undergo spin-glassy behavior above Neel temperature. Furthermore, a field-induced metamagnetic transition from AFM to ferromagnetic (FM) states is observed in these compounds. The calculated magnetic entropy changes show that all RCu{sub 2}Si{sub 2} and RCu{sub 2}Ge{sub 2} (R = Ho, Er) compounds, especially, ErCu{sub 2}Si{sub 2} exhibits large MCEs with no thermal hysteresis and magnetic hysteresis loss. The value of −ΔS{sub M}{sup max} reaches 22.8 J/Kg K for magnetic field changes from 0 to 5 T. In particular, for field changes of 1 and 2 T, the giant reversible magnetic entropy changes −ΔS{sub M}{sup max} are 8.3 and 15.8 J/kg K at 2.5 K, which is lower than the boiling point of helium. The low-field giant magnetic entropy change, together with ignorable thermal hysteresis and field hysteresis loss of ErCu{sub 2}Si{sub 2} compound is expected to have effective applications in low temperature magnetic refrigeration.

  6. Trap Depth Engineering of SrSi2O2N2:Ln2+,Ln3+(Ln2+= Yb, Eu; Ln3+= Dy, Ho, Er) Persistent Luminescence Materials for Information Storage Applications. (United States)

    Zhuang, Yixi; Lv, Ying; Wang, Le; Chen, Wenwei; Zhou, Tian-Liang; Takeda, Takashi; Hirosaki, Naoto; Xie, Rong-Jun


    Deep-trap persistent luminescence materials exhibit unique properties of energy storage and controllable photon release under additional stimulation, allowing for both wavelength and intensity multiplexing to realize high-capacity storage in the next-generation information storage system. However, the lack of suitable persistent luminescence materials with deep traps is the bottleneck of such storage technologies. In this study, we successfully developed a series of novel deep-trap persistent luminescence materials in the Ln 2+ /Ln 3+ -doped SrSi 2 O 2 N 2 system (Ln 2+ = Yb, Eu; Ln 3+ = Dy, Ho, Er) by applying the strategy of trap depth engineering. Interestingly, the trap depth can be tailored by selecting different codopants, and it monotonically increases from 0.90 to 1.18 eV in the order of Er, Ho, and Dy. This is well explained by the energy levels indicated in the host-referred binding energy scheme. The orange-red-emitting SrSi 2 O 2 N 2 :Yb,Dy and green-emitting SrSi 2 O 2 N 2 :Eu,Dy phosphors are demonstrated to be good candidates of information storage materials, which are attributed to their deep traps, narrow thermoluminescence glow bands, high emission efficiency, and excellent chemical stability. This work not only validates the suitability of deep-trap persistent luminescence materials in the information storage applications, but also broadens the avenue to explore such kinds of new materials for applications in anticounterfeiting and advanced displays.

  7. Features of magnetic and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} (x≤0.16) quasibinary compounds with R=Dy, Ho, Er

    Energy Technology Data Exchange (ETDEWEB)

    Anikin, Maksim; Tarasov, Evgeniy; Kudrevatykh, Nikolay [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation); Inishev, Aleksander [Institute of Metal Physics, Ekaterinburg 620137 (Russian Federation); Semkin, Mikhail; Volegov, Aleksey; Zinin, Aleksander [Institute of Natural Sciences, Ural Federal University, Ekaterinburg 620002 (Russian Federation)


    In this work the results of measurements of high field susceptibility, paraprocess susceptibility and thermal properties of R(Co{sub 1−x}Fe{sub x}){sub 2} intermetallic compounds (R=Dy, Ho, Er and x=(0−0.16)) are presented (heat capacity and magnetocaloric effect (MCE)). A magnetic structure of the Ho(Co{sub 0.88}Fe{sub 0.12}){sub 2} at 293 K and 78 K was studied by neutron powder diffraction. Some peculiarities of a high-field susceptibility were revealed at low temperatures and around the Curie point (T{sub C}). In temperature range lower than T{sub C} by (100–150) K, magnetic contributions to a zero-field heat capacity were found. Studying MCE in wide temperatures range, the large change of the entropy magnetic contribution (∆S) was observed which correlates with ∆T phenomenon. In particular, for the Er(Co{sub 0.84}Fe{sub 0.16}){sub 2} compound the ∆S value at low temperatures is six times higher than that at Curie point. The possible reasons of such behavior were discussed. - Highlights: • Magnetic and magnetocaloric properties of R(Co–Fe){sub 2} compounds have been studied. • Fe introduction induces the disorientation effect in Ho-ions magnetic ordering. • Emergence of magnetic contribution to a heat capacity at temperatures less T{sub C}. • The existence of a broad maximum on a temperature dependence of the MCE. • Direct MCE measurements at magnetic field of (0–17.5) kOe have been performed.

  8. Mononuclear lanthanide single molecule magnets based on the polyoxometalates [Ln(W5O18)2]9- and [Ln(beta2-SiW11O39)2]13- (Ln(III) = Tb, Dy, Ho, Er, Tm, and Yb). (United States)

    AlDamen, Murad A; Cardona-Serra, Salvador; Clemente-Juan, Juan M; Coronado, Eugenio; Gaita-Ariño, Alejandro; Martí-Gastaldo, Carlos; Luis, Fernando; Montero, Oscar


    The first two families of polyoxometalate-based single-molecule magnets (SMMs) are reported here. Compounds of the general formula [Ln(W(5)O(18))(2)](9-) (Ln(III) = Tb, Dy, Ho, and Er) and [Ln(SiW(11)O(39))(2)](13-) (Ln(III) = Tb, Dy, Ho, Er, Tm, and Yb) have been magnetically characterized with static and dynamic measurements. Slow relaxation of the magnetization, typically associated with SMM-like behavior, was observed for [Ln(W(5)O(18))(2)](9-) (Ln(III) = Ho and Er) and [Ln(SiW(11)O(39))(2)](13-) (Ln(III) = Dy, Ho, Er, and Yb). Among them, only the [Er(W(5)O(18))(2)](9-) derivative exhibited such a behavior above 2 K with an energy barrier for the reversal of the magnetization of 55 K. For a deep understanding of the appearance of slow relaxation of the magnetization in these types of mononuclear complexes, the ligand-field parameters and the splitting of the J ground-state multiplet of the lanthanide ions have been also estimated.

  9. Spectroscopic characterization and temporal dynamics of energy transfer process between Tm{sup 3+} -Ho{sup 3+} and Yb{sup 3+} -Tm{sup 3+} ions in LiYF{sub 4} and LiLuF{sub 4} crystals; Caracterizacao espectroscopica e dinamica temporal dos processos de transferencia de energia entre os ions Tm{sup 3+} -Ho{sup 3+} e Yb{sup 3+} -Tm{sup 3+} em cristais de LiYF{sub 4} and LiLuF{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Tarelho, Luiz Vicente Gomes


    In this work, we perform spectroscopic studies to characterize the energy transfer processes occurring in rare-earth doped lithium fluoride systems, aiming the optimization of the population inversion of these media. Yb{sup 3+} ion was used in order to probe the electron-phonon coupling in LiYF{sub 4}, LiGdF{sub 4} and LiLuF{sub 4} matrices. In these systems it was obtained the average phononenergy, the vibronic transition probability and Huang-Rhys coupling constant. These parameters are dependent on the crystal host and the LiLuF{sub 4} system presents excluded correlation effects, an electronic repulsion that weakens the vibronic coupling. The Tm:Ho:LiYF{sub 4} system was studied under diode laser pumping at 796 nm, aiming the 2 {mu}m emission optimization. The ideal conditions of concentration and laser power were determined favouring the latter emission. Upconversion processes of two photons were identified besides the energy transfer among ions. The dynamic processes of luminescence of donors and acceptors allowed one to classify the energy transfer process as an energy transfer process assisted by fast diffusion among donors. The spectroscopic study of the Yb:Tm:LiYF{sub 4} allowed the determination of efficient non resonant transfer mechanisms between ({sup 2}F{sub 5/2}) Ytterbium level and ({sup 3}H{sub 5}) Thulium level, assisted by two phonon with hopping migration among donors ( Foerster-Burshtein model). The repopulation process of the Yb donor level is due to a cooperative sensitization between Yb-Tm pairs followed by an energy transfer process. (author)

  10. Visible and near-infrared intense luminescence from water-soluble lanthanide [Tb(III), Eu(III), Sm(III), Dy(III), Pr(III), Ho(III), Yb(III), Nd(III), Er(III)] complexes. (United States)

    Quici, Silvio; Cavazzini, Marco; Marzanni, Giovanni; Accorsi, Gianluca; Armaroli, Nicola; Ventura, Barbara; Barigelletti, Francesco


    The synthesis of a new ligand (1) containing a single phenanthroline (phen) chromophore and a flexibly connected diethylenetriamine tetracarboxylic acid unit (DTTA) as a lanthanide (Ln) coordination site is reported [1 is 4-[(9-methyl-1,10-phenantrol-2-yl)methyl]-1,4,7-triazaheptane-1,1,7,7-tetraacetic acid]. From 1, an extended series of water-soluble Ln.1 complexes was obtained, where Ln is Eu(III), Tb(III), Gd(III), Sm(III), Dy(III), Pr(III), Ho(III), Yb(III), Nd(III), and Er(III). The stoichiometry for the association was found 1:1, with an association constant K(A) > or = 10(7) s(-1) as determined by employing luminescence spectroscopy. The luminescence and photophysical properties of the series of lanthanide complexes were investigated in both H2O and D2O solutions. High efficiencies for the sensitized emission, phi(se), in air-equilibrated water were observed for the Ln.1 complexes of Eu(III) and Tb(III) in the visible region (phi(se) = 0.24 and 0.15, respectively) and of Sm(III), Dy(III), Pr(III), Ho(III), Yb(III), Nd(III), and Er(III) in the vis and/or near-infrared region [phi(se) = 2.5 x 10(-3), 5 x 10(-4), 3 x 10(-5), 2 x 10(-5), 2 x 10(-4), 4 x 10(-5), and (in D2O) 4 x 10(-5), respectively]. For Eu.1 and Tb.1, luminescence data for water and deuterated water allowed us to estimate that no solvent molecules (q) are bound to the ion centers (q = 0). Luminescence quenching by oxygen was investigated in selected cases.

  11. Magnetic phase transitions in TbFe sub 2 Al sub 1 sub 0 , HoFe sub 2 Al sub 1 sub 0 and ErFe sub 2 Al sub 1 sub 0

    CERN Document Server

    Reehuis, M; Krimmel, A; Scheidt, E W; Stüsser, N; Loidl, A; Jeitschko, W


    The magnetic order of the orthorhombic aluminides TbFe sub 2 Al sub 1 sub 0 , HoFe sub 2 Al sub 1 sub 0 and ErFe sub 2 Al sub 1 sub 0 (space group Cmcm) has been studied by specific heat and magnetic measurements, as well as by neutron powder diffraction down to 100 mK and in external fields up to 5 T. Only the rare-earth ions carry a magnetic moment. At T = 1.5 K the terbium moments in TbFe sub 2 Al sub 1 sub 0 show a square-wave modulated magnetic order with wavevector k = (0, 0.7977, 0) and a moment direction parallel to the a-axis. At a critical field of H sub c sub 1 = 0.9 T one of ten spins is forced to flip, going into an intermediate ferrimagnetic phase that is stable up to the critical field H sub c sub 2 = 1.8 T. Above this field finally all the rest of the spins flip, resulting in a ferromagnetic order of the terbium moments. ErFe sub 2 Al sub 1 sub 0 orders antiferromagnetically below T sub N 1.77(7) K with a similar magnetic structure characterized by a wavevector k (0, approx 0.8, 0). In contras...

  12. Synthesis of Multicolor Core/Shell NaLuF₄:Yb(3+)/Ln(3+)@CaF₂ Upconversion Nanocrystals. (United States)

    Li, Hui; Hao, Shuwei; Yang, Chunhui; Chen, Guanying


    The ability to synthesize high-quality hierarchical core/shell nanocrystals from an efficient host lattice is important to realize efficacious photon upconversion for applications ranging from bioimaging to solar cells. Here, we describe a strategy to fabricate multicolor core @ shell α-NaLuF₄:Yb(3+)/Ln(3+)@CaF₂ (Ln = Er, Ho, Tm) upconversion nanocrystals (UCNCs) based on the newly established host lattice of sodium lutetium fluoride (NaLuF₄). We exploited the liquid-solid-solution method to synthesize the NaLuF₄ core of pure cubic phase and the thermal decomposition approach to expitaxially grow the calcium fluoride (CaF₂) shell onto the core UCNCs, yielding cubic core/shell nanocrystals with a size of 15.6 ± 1.2 nm (the core ~9 ± 0.9 nm, the shell ~3.3 ± 0.3 nm). We showed that those core/shell UCNCs could emit activator-defined multicolor emissions up to about 772 times more efficient than the core nanocrystals due to effective suppression of surface-related quenching effects. Our results provide a new paradigm on heterogeneous core/shell structure for enhanced multicolor upconversion photoluminescence from colloidal nanocrystals.

  13. The Novohrad Museum and Gallery in Lučenec past and present (História a súčasnosť Novohradského múzea a galérie v Lučenci

    Directory of Open Access Journals (Sweden)

    Michaela Škodová


    Full Text Available The Novohrad Museum and Gallery in Lučenec specializes in the regional history of enamel- and glass-making and visual arts. It holds a collection of over 30,000 art, archeo-logical, historical and ethnological objects. Since 1983, the musem and gallery have been a host to the annual Acquarelle Triennale and since 1989, it has hosted the oldest symposium of its kind in Slovakia, the International Ceramic Symposium, which showcases the contemporary ceramic production in Slovakia. This paper outlines the history of the museum and its focus, concentrating on the work done in the last decade.

  14. A family of 3d-4f octa-nuclear [Mn(III)(4)Ln(III)(4)] wheels (Ln = Sm, Gd, Tb, Dy, Ho, Er, and Y): synthesis, structure, and magnetism. (United States)

    Li, Mengyuan; Lan, Yanhua; Ako, Ayuk M; Wernsdorfer, Wolfgang; Anson, Christopher E; Buth, Gernot; Powell, Annie K; Wang, Zheming; Gao, Song


    We present the syntheses, crystal structures, and magnetochemical characterizations for a family of isostructural [Mn(4)Ln(4)] compounds (Ln = Sm, Gd, Tb, Dy, Ho, Er, and Y). They were prepared from the reactions of formic acid, propionic acid, N-n-butyl-diethanolamine, manganese perchlorate, and lanthanide nitrates under the addition of triethylamine in MeOH. The compounds possess an intriguing hetero-octanuclear wheel structure with four Mn(III) and four Ln(III) ions alternatively arranged in a saddle-like ring, where formate ions act as key carboxylate bridges. In the lattice, the molecules stack into columns in a quasi-hexagonal arrangement. Direct current (dc) magnetic susceptibility measurements indicated the depopulation of the Stark components at low temperature and/or very weak antiferromagnetic interactions between magnetic centers. The zero-field alternating current (ac) susceptibility studies revealed that the compounds containing Sm, Tb, and Dy showed frequency-dependent out-of-phase signals, indicating they are single-molecule magnets (SMMs). Magnetization versus applied dc field sweeps on a single crystal of the Dy compound down to 40 mK exhibited hysteresis depending on temperatures and field sweeping rates, further confirming that the Dy compound is a SMM. The magnetization dynamics of the Sm and Y compounds investigated under dc fields revealed that the relaxation of the Sm compound is considered to be dominated by the two-phonon (Orbach) process while the Y compound displays a multiple relaxation process.

  15. A Dy4 single-molecule magnet and its Gd(iii), Tb(iii), Ho(iii), and Er(iii) analogues encapsulated by an 8-hydroxyquinoline Schiff base derivative and β-diketonate coligand. (United States)

    Gao, Hong-Ling; Zhou, Xiao-Pu; Bi, Yan-Xia; Shen, Hai-Yun; Wang, Wen-Min; Wang, Ni-Ni; Chang, Yi-Xin; Zhang, Ru-Xia; Cui, Jian-Zhong


    Five new tetranuclear complexes based on an 8-hydroxyquinoline Schiff base derivative and the β-diketone coligand, [Ln4(acac)4L6(μ3-OH)2]·CH3CN·0.5CH2Cl2 (Ln = Gd (1), Tb (2), Dy (3), Ho (4) and Er (5); HL = 5-(benzylidene)amino-8-hydroxyquinoline; acac = acetylacetonate) have been synthesized, and structurally and magnetically characterized. Complexes 1-5 have similar tetranuclear structures. Each LnIII ion is eight coordinated and its coordination polyhedra can be described as being in a distorted square-antiprismatic geometry. The magnetic studies reveal that 1 features the magnetocaloric effect (MCE) with the magnetic entropy change of -ΔSm(T) = 25.08 J kg-1 K-1 at 2 K for ΔH = 7 T, and 3 displays the slow magnetic relaxation behavior of Single Molecule Magnets (SMMs) with the anisotropic barrier of 86.20 K and the pre-exponential factor τ0 = 2.99 × 10-8 s.

  16. Correlation between slow magnetic relaxation and the coordination structures of a family of linear trinuclear Zn(II)-Ln(III)-Zn(II) complexes (Ln = Tb, Dy, Ho, Er, Tm and Yb). (United States)

    Maeda, Moe; Hino, Shiori; Yamashita, Kei; Kataoka, Yumiko; Nakano, Motohiro; Yamamura, Tomoo; Kajiwara, Takashi


    Six linear trinuclear [Ln{Zn(L)(AcO)}(2)]BPh(4) complexes (H(2)L denotes the Schiff-base ligand formed by a condensation reaction between ethylenediamine and two equivalents of o-vanillin), including Ln = Tb (1), Dy (2), Ho (3), Er (4), Tm (5) and Yb (6) were synthesized and were confirmed to be isostructural via X-ray crystallographic analyses. The Ln(III) ion in each complex is deca-coordinated by four equatorial oxygen donors from the methoxo groups of the Schiff-base ligands, two oxygen donors from the acetate anions and four axial oxygen donors from the phenoxo groups of the Schiff-base ligands. AC susceptibility measurements, with an oscillating frequency of 10 to 10,000 Hz, revealed that 1, 2, 4 and 6 show slow magnetic relaxation under a 1000 Oe DC bias field, which occurs via a single process, as confirmed by the semi-circular Cole-Cole plots. These complexes are considered to be field-induced single-molecule magnets under these conditions. The presence or absence of the slow magnetic relaxation process is discussed by correlating the characteristic magnetic anisotropy of each Ln(III) ion with the ligand field anisotropy.

  17. Synthesis of Multicolor Core/Shell NaLuF4:Yb3+/Ln3+@CaF2 Upconversion Nanocrystals (United States)

    Li, Hui; Hao, Shuwei; Yang, Chunhui; Chen, Guanying


    The ability to synthesize high-quality hierarchical core/shell nanocrystals from an efficient host lattice is important to realize efficacious photon upconversion for applications ranging from bioimaging to solar cells. Here, we describe a strategy to fabricate multicolor core @ shell α-NaLuF4:Yb3+/Ln3+@CaF2 (Ln = Er, Ho, Tm) upconversion nanocrystals (UCNCs) based on the newly established host lattice of sodium lutetium fluoride (NaLuF4). We exploited the liquid-solid-solution method to synthesize the NaLuF4 core of pure cubic phase and the thermal decomposition approach to expitaxially grow the calcium fluoride (CaF2) shell onto the core UCNCs, yielding cubic core/shell nanocrystals with a size of 15.6 ± 1.2 nm (the core ~9 ± 0.9 nm, the shell ~3.3 ± 0.3 nm). We showed that those core/shell UCNCs could emit activator-defined multicolor emissions up to about 772 times more efficient than the core nanocrystals due to effective suppression of surface-related quenching effects. Our results provide a new paradigm on heterogeneous core/shell structure for enhanced multicolor upconversion photoluminescence from colloidal nanocrystals. PMID:28336867

  18. Family of carboxylate- and nitrate-diphenoxo triply bridged dinuclear Ni(II)Ln(III) complexes (Ln = Eu, Gd, Tb, Ho, Er, Y): synthesis, experimental and theoretical magneto-structural studies, and single-molecule magnet behavior. (United States)

    Colacio, Enrique; Ruiz, José; Mota, Antonio J; Palacios, María A; Cremades, Eduard; Ruiz, Eliseo; White, Fraser J; Brechin, Euan K


    Seven acetate-diphenoxo triply bridged M(II)-Ln(III) complexes (M(II) = Ni(II) and Ln(III) = Gd, Tb, Ho, Er, and Y; M(II) = Zn(II) and Ln(III) = Ho(III) and Er(III)) of formula [M(μ-L)(μ-OAc)Ln(NO(3))(2)], one nitrate-diphenoxo triply bridged Ni(II)-Tb(III) complex, [Ni(μ-L)(μ-NO(3))Tb(NO(3))(2)]·2CH(3)OH, and two diphenoxo doubly bridged Ni(II)-Ln(III) complexes (Ln(III) = Eu, Gd) of formula [Ni(H(2)O)(μ-L)Ln(NO(3))(3)]·2CH(3)OH have been prepared in one pot reaction from the compartmental ligand N,N',N"-trimethyl-N,N"-bis(2-hydroxy-3-methoxy-5-methylbenzyl)diethylenetriamine (H(2)L). Moreover, Ni(II)-Ln(III) complexes bearing benzoate or 9-anthracenecarboxylate bridging groups of formula [Ni(μ-L)(μ-BzO)Dy(NO(3))(2)] and [Ni(μ-L)(μ-9-An)Dy(9-An)(NO(3))(2)]·3CH(3)CN have also been successfully synthesized. In acetate-diphenoxo triply bridged complexes, the acetate bridging group forces the structure to be folded with an average hinge angle in the M(μ-O(2))Ln bridging fragment of ~22°, whereas nitrate-diphenoxo doubly bridged complexes and diphenoxo-doubly bridged complexes exhibit more planar structures with hinge angles of ~13° and ~2°, respectively. All Ni(II)-Ln(III) complexes exhibit ferromagnetic interactions between Ni(II) and Ln(III) ions and, in the case of the Gd(III) complexes, the J(NiGd) coupling increases weakly but significantly with the planarity of the M-(O)(2)-Gd bridging fragment and with the increase of the Ni-O-Gd angle. Density functional theory (DFT) theoretical calculations on the Ni(II)Gd(III) complexes and model compounds support these magneto-structural correlations as well as the experimental J(NiGd) values, which were found to be ~1.38 and ~2.1 cm(-1) for the folded [Ni(μ-L)(μ-OAc)Gd(NO(3))(2)] and planar [Ni(H(2)O)(μ-L)Gd(NO(3))(3)]·2CH(3)OH complexes, respectively. The Ni(II)Dy(III) complexes exhibit slow relaxation of the magnetization with Δ/k(B) energy barriers under 1000 Oe applied magnetic fields of 9.2 and 10

  19. Structural and magnetic studies on the new Laves phases RE(Co0.667Ga0.333)2 (RE = Gd, Tb, Dy, Ho, and Er). Magnetocaloric effect of Gd(Co0.667Ga0.333)2 (United States)

    Yuan, Fang; Greedan, John E.; Mozharivskyj, Yurij


    Several new MgZn2-type Laves phases with the P63/mmc symmetry and RE(Co0.667Ga0.333)2 stoichiometries (RE = Gd, Tb, Dy, Ho, and Er) were obtained by arc-melting and subsequent annealing. Single crystals with the MgZn2-type structure were extracted from the annealed RE(Co0.667Ga0.333)2 (RE = Gd, Tb, Dy, and Ho) alloys and Ga flux-grown Er(Co0.667Ga0.333)2 sample. Powder and single-crystal X-ray diffraction methods were used for the phase analysis and structural characterization. A decrease in the cell volume due to the lanthanide contraction is observed from Gd(Co0.667Ga0.333)2 to Er(Co0.667Ga0.333)2. RE atoms occupy the 4f site, while Co and Ga are in the 2a and 6h sites. Magnetic behavior of the hexagonal MgZn2-type RE(Co0.667Ga0.333)2 phases strongly depends on the RE. Apparent ferromagnetic transition is observed for RE = Gd, Tb, and Dy, while the other two phases (RE = Ho, and Er) seem to be ferrimagnetic. Magnetocaloric properties of the Gd(Co0.667Ga0.333)2 phase were measured; the small isothermal magnetic entropy change (ΔSiso) value of -4.94 J/kgK at 152 K and for a ΔH = 0-50 kOe field change suggests a conventional magnetocaloric effect.

  20. Studies of the energy transfer processes from Er{sup 3+} and Ho{sup 3+} to Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+} in LiYF{sub 4} crystal and ZBLAN glass for the laser media optimization operating near 3{mu}m region; Estudos dos processos de transferencia de energia dos ions de Er{sup 3+} e Ho{sup 3+} para os ions de Nd{sup 3+}, Tb{sup 3+} e Eu{sup 3+} no cristal de LiYF{sub 4} e no vidro ZBLAN para a otimizacao de meios laser ativos que operam na regiao de 3{mu}m

    Energy Technology Data Exchange (ETDEWEB)

    Jagosich, Fabio Henrique


    The energy transfer processes (ET) from the {sup 4}I{sub 13/2}; {sup 4}I{sub 11/2} levels of Er{sup 3+} and {sup 5}I{sub 6} levels of Ho{sup 3+} ions in LiYF{sub 4} (YLF) crystal and ZBLAN glass to Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+} deactivators ions were studied. The micro parameters of these energy transfer processes were determined using the overlap integral method, and showed that Eu{sup 3+} ion is the best deactivator of the first excited state of the Ho{sup 3+} in YLF, and Nd{sup 3+} is the best deactivator of the Er{sup 3+} in YLF and ZBLAN materials. The 1.5 and 2.7{mu}m emissions of Er{sup 3+} and 2.1 and 2.9{mu}m fluorescence of Ho{sup 3+} were measured using short laser pulses excitations from a tunable OPO pumped 2w-Nd:YAG laser system. We proposed a criterion for discriminating the energy transfer processes assisted by excitation migration (diffusion or hopping) among donors. It was observed that diffusion model describes the ET process from the second excited state of the donor (Er{sup 3+} or Ho{sup 3+}) independently of the C{sub D-D}/C{sub D-A} ratio, while the hopping model can describe the ET process involving the first excited state of donor. We proposed a modification of the hopping model in order to describe the experimental results for systems having C{sub D-D}/C{sub D-A} {>=} 10. Using the ET parameters, we determined that the best systems for laser action at 3{mu}m are the Ho:Eu:YLF, Ho:Nd:YLF and Er:Nd:YLF systems. On the other hand, we found that Er{sup 3+} doped (1.5 mol%) ZBLAN glasses, single and co-doped with Nd{sup 3+}, Tb{sup 3+} or Eu{sup 3+}, do not show potential for laser action at 2.8{mu}m. The up-conversion processes were studied in Er:YLF systems as a function of the Er{sup 3+} concentration, and the excited state absorption (ESA) and up conversion by energy transfer (ETU) processes were discriminated using a time resolved fluorescence decays. It was observed that 980 nm is the most convenient wavelength for pumping the Er

  1. Research on the effects of resistance training on the special strength of judoists Výzkum účinku silového tréninku na speciální sílu judistů

    Directory of Open Access Journals (Sweden)

    Goran Kasum


    áklad pro dosažení nejvyšších výsledků. Je obvyklé, že kondiční trénink judistů je plánován tak, aby zahrnoval tři hlavní fáze, přičemž každá z nich je charakterizována svou vlastní speciální dynamikou: – fáze 1: skládá se z práce zahrnuté v tréninkovém programu, jehož cílem je rozvoj tzv. hlavních základů (síla a vytrvalost, což zabere velkou část celkového všestranného tréninku; – fáze 2: vyžaduje menší množství celkové práce, ale větší intenzitu námahy, aby se rozvinuly tzv. specifické soutěživé základy judistů; – fáze 3: kondiční příprava vytváří specifické schopnosti, hbitost, motorické a situačně-motorické dovednosti závodníka. Cílem tohoto výzkumu je ukázat základní principy tréninkového procesu v přípravném období, aplikaci tohoto modelu v tréninku zaměřeném na specifickou sílu judistů a změny, které nastávají díky aplikaci tohoto tréninkového modelu; během celého období probíhal výzkum. Tento výzkum zahrnoval judisty, kteří se účastnili soutěží na národní úrovni. K ověření speciální síly judistů bylo použito šest testů. Výsledky výzkumu ukazují, že během experimentálního zpracování (přípravné období bylo určeno statisticky významné zvýšení speciální síly judistů, a to prostřednictvím všech testů, kterých bylo pro měření použito.

  2. Assembly of heterobimetallic Ni(II)-Ln(III) (Ln(III) = Dy(III), Tb(III), Gd(III), Ho(III), Er(III), Y(III)) complexes using a ferrocene ligand: slow relaxation of the magnetization in Dy(III), Tb(III) and Ho(III) analogues. (United States)

    Chakraborty, Amit; Bag, Prasenjit; Rivière, Eric; Mallah, Talal; Chandrasekhar, Vadapalli


    A family of dinuclear 3d-4f heterobimetallic complexes [LNi(H2O)(μ-OAc)Ln(NO3)2]·CH3CN; {Ln = Dy(III) (1), Tb(III) (2), Ho(III) (3), Gd(III) (4), Er(III) (5), Y(III) (6)} have been synthesized by utilizing a ferrocene-based, dual compartmental ligand H2L. 1-6 are isostructural and crystallize in the triclinic (P1) space group. In these complexes Ni(II) is present in the inner coordination sphere of the dianionic [L](2-) ligand; Ln(III) is encapsulated in the outer coordination pocket. Ni(II) shows a 2N, 4O coordination environment in a distorted octahedral geometry, while the Ln(III) ion possesses a 9O coordination environment in a distorted tricapped trigonal prismatic geometry. ESI-MS studies suggest that the structural integrity of 1-6 is retained in solution. Electrochemical studies reveal that these complexes show a reversible one-electron response typical of the ferrocene motif along with an irreversible one-electron oxidation involving the Ni(II)/Ni(III) couple. Magnetic studies revealed the presence of ferromagnetic exchange coupling between Ni(II) and Ln(III) centers as shown by the increase of χMT value upon cooling below 50 K for compounds 1, 2, 4 and 5. Further, dynamic magnetic susceptibility measurements (1-3) confirm the absence of an out-of-phase (χ'') signal at zero dc fields. However, when these measurements were carried out at 1000 Oe dc field the χ'' signal was observed, although maxima could not be detected up to 2 K.

  3. Systematic Study of a Family of Butterfly-Like {M2Ln2} Molecular Magnets (M = Mg(II), Mn(III), Co(II), Ni(II), and Cu(II); Ln = Y(III), Gd(III), Tb(III), Dy(III), Ho(III), and Er(III)). (United States)

    Moreno Pineda, Eufemio; Chilton, Nicholas F; Tuna, Floriana; Winpenny, Richard E P; McInnes, Eric J L


    A family of 3d-4f [M(II)2Ln(III)2(μ3-OH)2(O2C(t)Bu)10](2-) "butterflies" (where M(II) = Mg, Co, Ni, and Cu; Ln(III) = Y, Gd, Tb, Dy, Ho, and Er) and [Mn(III)2Ln(III)2(μ3-O)2(O2C(t)Bu)10](2-) molecules (where Ln(III) = Y, Gd, Tb, Dy, Ho, and Er) has been synthesized and characterized through single-crystal X-ray diffraction, SQUID magnetometry, and ab initio calculations. All dysprosium- and some erbium-containing tetramers showed frequency-dependent maxima in the out-of-phase component of the susceptibility associated with slow relaxation of magnetization, and hence, they are single-molecule magnets (SMMs). AC susceptibility measurements have shown that the SMM behavior is entirely intrinsic to the Dy and Er sites and the magnitude of the energy barrier is influenced by the interactions between the 4f and the 3d metal. A trend is observed between the strength of the 3d-4f exchange interaction between and the maximum observed in the χ″M(T).

  4. Teorie lidského kapitálu


    Kadlecová, Lucie


    This work is concerned with Human Capital Theory. Part of the work is concentrate on evolution of Theory in economic throught, than author explains what the term Human Capital means. Critique of Human Capital, investments in Human Capital and also Human Capital at labor market are described. The work is finished by Human Capital and economic growth.

  5. Study by neutron diffusion of the grain-aligned powders HoBa{sub 2}Cu{sub 3}O{sub x} (x=7, 6.2), ErBa{sub 2}Cu{sub 3}O{sub 7} and of a single crystal Nd{sub 1+y}Ba{sub 2-y-z}Sr{sub z}Cu{sub 3}O{sub 6.7}; Etude par diffusion neutronique des composes orientes HoBa{sub 2}Cu{sub 3}O{sub x} (x=7, 6.2), ErBa{sub 2}Cu{sub 3}O{sub 7} et d`un cristal Nd{sub 1+y}Ba{sub 2-y-z}Sr{sub z}Cu{sub 3}O{sub 6.7}

    Energy Technology Data Exchange (ETDEWEB)

    Fauth, F. [Paul Scherrer Inst. (PSI), Villigen (Switzerland)


    Inelastic neutron scattering from single crystals is the most powerful tool to determine the nature and the size of the magnetic interactions between the R{sup 3+} ions in the high-Tc compounds RBa{sub 2}CuO{sub x}. Due to the absence of sufficiently large and perfect crystals we performed our measurements in grain-aligned powders of compounds HoBa{sub 2}Cu{sub 3}O{sub x} (x=7, 6.2)and ErBa{sub 2}Cu{sub 3}O{sub 7}. By analyzing the energy dispersions and the intensity evolution of the collective magnetic excitations, we determined the magnetic exchange parameters between the rare-earth ions. In RBa{sub 2}Cu{sub 3}O{sub 7} the crystalline electric field acting on the rare-earth ion induces a strong anisotropy in the single-ion susceptibility. At high temperatures, the easy axis of magnetization lies along the c axis and in the ab plane for HoBa{sub 2}Cu{sub 3}O{sub 7} and ErBa{sub 2}Cu{sub 3}O{sub 7}, respectively. It follows from this property that the application of an external magnetic field results in an alignment of the grains along the easy axis of magnetization. The quality of the alignment was measured by neutron diffraction. In both samples the mosaic turned out to be about 22{sup o}. Whereas the grain-aligned HoBa{sub 2}Cu{sub 3}O{sub x} samples were uniquely oriented along the c axis, the grain-aligned ErBa{sub 2}Cu{sub 3}O{sub 7} sample was equally oriented along the a and b axes. The tetragonal phase HoBa{sub 2}Cu{sub 3}O{sub 6.2} was obtained from the grain-aligned HoBa{sub 2}Cu{sub 3}O{sub 7} sample by a temperature-controlled desorption-absorption procedure. We measured in the paramagnetic phase of HoBa{sub 2}Cu{sub 3}O{sub x} (x=7, 6.2) the magnetic excitation associated with the lowest ground state crystalline electric field (CEF) transition. Finally, we determined the chemical structure of a single crystal Nd{sub 1+y}Ba{sub 2-y-}zSr{sub z}Cu{sub 3}O{sub x} from 4-circle diffractometer data. (Abstract Truncated)

  6. Radiative lifetimes, branching fractions, and transition probabilities for Lu I, Lu II, and Lu III (United States)

    Fedchak, J. A.; den Hartog, E. A.; Lawler, J. E.; Biemont, E.; Palmeri, P.; Quinet, P.


    In astrophysics, rare-earth abundances are particularly relevant to the study of chemically peculiar stars, stellar nucleosynthesis, and other problems. Accurate oscillator strengths are required to disentangle blends and obtain reliable abundance values. Rare-earth salts are also used in many commercial metal-halide high intensity discharge lamps. Accurate transition probabilities are required in the models used for lamp design and for diagnostics. We have determined accurate radiative lifetimes for the first three spectra of Lu using time-resolved laser-induced fluorescence on a slow beam of Lu ions and atoms. Lu I branching fractions have been determined from an emission spectra taken with a 1.0 m Fourier transform spectrometer at the National Solar Observatory (NSO). These are combined with the radiative lifetimes to produce 38 accurate transition probabilities for Lu I. The Lu I measurements are compared to new relativistic Hartree-Fock calculations.

  7. The MueLu Tutorial

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jonathan Joseph [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wiesner, Tobias A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Prokopenko, Andrey [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gee, Michael [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    The MueLu tutorial is written as a hands-on tutorial for MueLu, the next generation multigrid framework in Trilinos. It covers the whole spectrum from absolute beginners’ topics to expert level. Since the focus of this tutorial is on practical and technical aspects of multigrid methods in general and MueLu in particular, the reader is expected to have a basic understanding of multigrid methods and its general underlying concepts. Please refer to multigrid textbooks (e.g. [1]) for the theoretical background.

  8. Možnosti využití metody eyetrackingu ve výzkumu kompetencí historického myšlení na příkladu analýzy ikonografického materiálu/ Possibilities of using eye tracking method in the research of historical thinking competencies based on the example of historical cartoon analysis

    Directory of Open Access Journals (Sweden)

    Denisa Labischová


    Full Text Available Empirická studie pojednává o perspektivách využití metody eyetrackingu, založené na sledování očních pohybů při percepci verbálního a ikonického textu, a přináší výsledky předvýzkumu z roku 2014, jehož cílem bylo ověřit výzkumný nástroj pro zkoumání vlivu konkrétního způsobu strukturace analýzy historické karikatury na kvalitu její interpretace respondenty. V první kapitole jsou vymezena teoretická východiska (význam historických pramenů v procesu rozvíjení kompetencí historického myšlení a jsou zde uvedeny možnosti uplatnění eyetrackingu v pedagogickém výzkumu. Ve druhé kapitole jsou popsány použité metody sběru a zpracování dat. Zvolen byl smíšený výzkumný přístup, zahrnující analýzu audiozáznamů slovních odpovědí studentů a statistických i vizualizovaných dat získaných elektronickým měřením. Testováno bylo 23 studentů učitelství z Moravskoslezského kraje. Ve třetí kapitole jsou prezentována výzkumná zjištění – návrh kategoriálního systému pro interpretaci karikatury, vizualizace dat v podobě heatmap, gaze opacity map a gaze plots a nejvýznamnější kvantitativní data (rozdíly v četnosti a délce očních fixací v průběhu testu. Předvýzkum ukázal, že eyetracking může poskytnout jinými metodami obtížně zjistitelné informace o percepčních strategiích uplatňovaných při interpretaci textu. Výsledky naznačují, že v případě didakticky strukturované analýzy historické karikatury dosahují respondenti vyšší úrovně interpretace než při analýze nestrukturované, kdy se slovní odpovědi omezují převážně na zobrazené osobnosti a jsou opomíjeny důležité symboly, obrazové kódy i širší historický kontext.

  9. Separation and Recycling for Rare Earth Elements by Homogeneous Liquid-Liquid Extraction (HoLLE Using a pH-Responsive Fluorine-Based Surfactant

    Directory of Open Access Journals (Sweden)

    Shotaro Saito


    Full Text Available A selective separation and recycling system for metal ions was developed by homogeneous liquid-liquid extraction (HoLLE using a fluorosurfactant. Sixty-two different elemental ions (e.g., Ag, Al, As, Au, B, Ba, Be, Bi, Ca, Cd, Ce, Co, Cr, Cu, Dy, Er, Eu, Fe, Ga, Gd, Ge, Hf, Hg, Ho, In, Ir, La, Lu, Mg, Mn, Mo, Nb, Nd, Ni, Os, P, Pb, Pd, Pr, Pt, Re, Rh, Ru, Sb, Sc, Se, Si, Sm, Sn, Sr, Ta, Tb, Te, Ti, Tl, Tm, V, W, Y, Yb, Zn, and Zr were examined. By changing pH from a neutral or alkaline solution (pH ≥ 6.5 to that of an acidic solution (pH < 4.0, gallium, zirconium, palladium, silver, platinum, and rare earth elements were extracted at >90% efficiency into a sedimented Zonyl FSA® (CF3(CF2n(CH22S(CH22COOH, n = 6–8 liquid phase. Moreover, all rare earth elements were obtained with superior extraction and stripping percentages. In the recycling of rare earth elements, the sedimented phase was maintained using a filter along with a mixed solution of THF and 1 M sodium hydroxide aqueous solution. The Zonyl FSA® was filtrated and the rare earth elements were recovered on the filter as a hydroxide. Furthermore, the filtrated Zonyl FSA was reusable by conditioning the subject pH.

  10. The oxonitridoborate Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} and the mixed-valent borates Sr{sub 3}Ln{sub 2}(BO{sub 3}){sub 4} (Ln = Ho, Er)

    Energy Technology Data Exchange (ETDEWEB)

    Hoeppe, Henning A.; Kazmierczak, Karolina; Grumbt, Christine; Schindler, Lisa [Institut fuer Physik, Universitaet Augsburg (Germany); Schellenberg, Inga; Poettgen, Rainer [Westfaelische Wilhelms-Universitaet Muenster, Institut fuer Anorganische und Analytische Chemie (Germany)


    The crystal structures of the mixed borates Sr{sub 3}Er{sub 2}(BO{sub 3}){sub 4} [Pnma, no. 62, Z = 4, a = 738.08(2), b = 1588.94(4), c = 867.81(2) pm, 683 reflections, 70 parameters, R1 = 0.037, wR2 = 0.077] and Sr{sub 3}Ho{sub 2}(BO{sub 3}){sub 4} [Pnma, no. 62, Z = 4, a = 738.45(7), b = 1591.55(12), c = 871.03(9) pm, 691 reflections, 59 parameters, R1 = 0.069, wR2 = 0.098] and europium oxonitridoborate Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} [Pnma, no. 62, Z = 12, a = 2232.2(5), b = 1603.1(3), c = 879.59(18) pm, 2880 reflections, 313 parameters, R1 = 0.027, wR2 = 0.059] were solved from single-crystal X-ray diffraction data. Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} adopts a threefold superstructure of the structure of Sr{sub 3}Ln{sub 2}(BO{sub 3}){sub 4} (Ln = Ho, Er). In both structure types, the different cations are situated on common sites with a pronounced preferential occupation but no complete ordering. These conclusions are based on the crystal structure refinement, {sup 151}Eu Moessbauer spectroscopy and MAPLE (Madelung part of lattice energy) calculations. The proposed Eu{sub 5}(BO{sub 3}){sub 4} contains nitrogen and has a formula Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} as confirmed by {sup 151}Eu Moessbauer spectroscopy. The optical reflectance spectrum of Eu{sub 5}(BO{sub 2.51(7)}N{sub 0.49(7)}){sub 4} is in accordance with the yellow colour of the compound. (Copyright copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  11. Sulfate Exchange of the Nitrate-Type Layered Hydroxide Nanosheets of Ln2(OH)5NO3· nH2O for Better Dispersed and Multi-color Luminescent Ln2O3 Nanophosphors (Ln = Y0.98RE0.02, RE = Pr, Sm, Eu, Tb, Dy, Ho, Er, and Tm) (United States)

    Wu, Xiaoli; Liu, Weigang; Li, Ji-Guang; Zhu, Qi; Li, Xiaodong; Sun, Xudong


    Through restricting thickness growth by performing coprecipitation at the freezing temperature of ~4 °C, solid-solution nanosheets (up to 5-nm thick) of the Ln2(OH)5NO3· nH2O layered hydroxide (Ln = Y0.98RE0.02; RE = Pr, Sm, Eu, Tb, Dy, Ho, Er, and Tm, respectively) were directly synthesized without performing conventional exfoliation. In situ exchange of the interlayer NO3 - with SO4 2- produced a sulfate derivative [Ln2(OH)5(SO4)0.5· nH2O] of the same layered structure and two-dimensional crystallite morphology but substantially contracted d 002 basal spacing (from ~0.886 to 0.841 nm). The sulfate derivative was systematically compared against its nitrate parent in terms of crystal structure and phase/morphology evolution upon heating. It is shown that the interlayer SO4 2-, owing to its bonding with the hydroxide main layer, significantly raises the decomposition temperature from ~600 to 1000 °C to yield remarkably better dispersed oxide nanopowders via a monoclinic Ln2O2SO4 intermediate. The resultant (Y0.98RE0.02)2O3 nanophosphors were studied for their photoluminescence to show that the emission color, depending on RE3+, spans a wide range in the Commission Internationale de l'Eclairage (CIE) chromaticity diagram, from blue to deep red via green, yellow, orange, and orange red.

  12. Baicalein protects rat insulinoma INS-1 cells from palmitate-induced lipotoxicity by inducing HO-1.

    Directory of Open Access Journals (Sweden)

    Hyun Jeong Kwak

    Full Text Available β-Cell dysfunction plays a central role in the pathogenesis of type 2 diabetes (T2D, and the identification of novel approaches to improve β-cell function is essential to treat this disease. Baicalein, a flavonoid originally isolated from the root of Scutellaria Baicalensis, has been shown to have beneficial effects on β-cell function. Here, the authors investigated the molecular mechanism responsible for the protective effects of baicalein against palmitate (PA-induced impaired β-cell function, and placed focus on the role of heme oxygenase (HO-1.Rat pancreatic β-cell line INS-1 cells or mouse pancreatic islets were cultured with PA (500 μM to induce lipotoxicity in the presence or absence of baicalein (50 μM, and the expressions of the ER stress markers, ATF-3, CHOP and GRP78 were detected by Western blotting and/or qPCR. The involvement of HO-1 was evaluated by HO-1 siRNA transfection and using the HO-1 inhibitor ZnPP.Baicalein reduced PA-induced ER stress and inflammation and enhanced insulin secretion, and these effects were associated with the induction of HO-1. Furthermore, these protective effects were attenuated by ZnPP and by HO-1 siRNA. Pretreatment of PD98059 (an ERK inhibitor significantly inhibited the protective effects of baicalein and blocked HO-1 induction. On the other hand, CO production by RuCO (a CO donor ameliorated PA-induced ER stress, suggesting that CO production followed by HO-1 induction may contribute to the protective effects of baicalein against PA-induced β-cell dysfunction.Baicalein protects pancreatic β-cells from PA-induced ER stress and inflammation via an ERK-HO-1 dependent pathway. The authors suggest HO-1 induction in pancreatic β-cells appears to be a promising therapeutic strategy for T2D.

  13. Sexual attitudes of personnel who work with individuals with intellectual disability [Postoje personálu pracujícího s osobami s mentálním postižením vůči sexualitě

    Directory of Open Access Journals (Sweden)

    Jana Divišová-Brettová


    Full Text Available The capacity, in the Czech Republic, for measuring attitudes towards this important aspect of a person's life is limited by the lack of an appropriate instrument. The aim of this study was to adapt the new instrument "Attitudes to Sexuality Questionnaire" (Cuskelly & Gilmore, 2007 and translate it into the Czech language. The purpose of this study was to examine, in the pilot study, the attitudes of schoolmasters toward the sexuality of persons with intellectual disability. From among Special Olympics participants, 20 persons (n = 20, 11 females and 9 males were enrolled in this study. From the results it is apparent that respondents held positive attitudes toward people with intellectual disability and toward people from the general population. The most positive views were toward the non reproductive sexual behaviour subscale. The less positive views were presented toward the sexual rights subscale. A review of the literature contained a comparison of the situation in social systems providing services for people with intellectual disability in Australia and the Czech Republic and the development of the attitudes toward the sexuality of people with intellectual disability. [Česká republika bohužel disponuje malým počtem vhodných instrumentů k měření postojů vůči sexualitě – tomuto důležitému aspektu lidského života. Cílem této práce bylo adaptovat nový instrument "Dotazník o postojích vůči sexualitě" (Cuskelly & Gilmore, 2007 a přeložit jej do češtiny. Tento dotazník je původem z Austrálie a autorka Monica Cuskelly písemně souhlasila s přeložením a používáním jejího dotazníku v České republice. Dalším cílem této práce byla v pilotní studii evaluace postojů vychovatelů vůči sexualitě osob s mentálním postižením a vůči sexualitě osob z běžné populace. Zůčastnilo se 20 osob (11 žen a 9 mužů, které byly vybrány na speciální olympiádě. Z výsledků je zřejmé, že ú

  14. Evaluating the electronic structure of formal LnII ions in LnII(C5H4SiMe3)3 1– using XANES spectroscopy and DFT calculations† †Electronic supplementary information (ESI) available: The results from quantum chemical ab initio FEFF9.6 code calculations for LnII L3-edges from Ln(C5H4SiMe3)3 x– (Ln = Sm, Tm, Y; x = 0, 1) and second derivative analysis of the lanthanides are in the ESI.† Our branching ratio analysis, the PBE//TZP optimized ground-state geometrical xyz coordinates and XC//TZ2P (XC = PBE, BLYP, B3LYP, BHandHLYP), single-point calculated total bonding energies of Ln(C5H4SiMe3)3 1–/0 (Ln = Sm, Ho), and relative single-point energy difference in kcal mol–1 between 4f10 5d1 and 4f11 5d0 in HoII(C5H4SiMe3)3 1– from different functional results at the PBE//TZP optimized ground-state geometries are also included. See DOI: 10.1039/c7sc00825b Click here for additional data file. (United States)

    Fieser, Megan E.; Ferrier, Maryline G.; Su, Jing; Cary, Samantha K.; Engle, Jonathan W.; Lezama Pacheco, Juan S.; Olson, Angela C.; Ryan, Austin J.; Stein, Benjamin W.; Wagner, Gregory L.; Woen, David H.; Vitova, Tonya


    The isolation of [K(2.2.2-cryptand)][Ln(C5H4SiMe3)3], formally containing LnII, for all lanthanides (excluding Pm) was surprising given that +2 oxidation states are typically regarded as inaccessible for most 4f-elements. Herein, X-ray absorption near-edge spectroscopy (XANES), ground-state density functional theory (DFT), and transition dipole moment calculations are used to investigate the possibility that Ln(C5H4SiMe3)3 1– (Ln = Pr, Nd, Sm, Gd, Tb, Dy, Y, Ho, Er, Tm, Yb and Lu) compounds represented molecular LnII complexes. Results from the ground-state DFT calculations were supported by additional calculations that utilized complete-active-space multi-configuration approach with second-order perturbation theoretical correction (CASPT2). Through comparisons with standards, Ln(C5H4SiMe3)3 1– (Ln = Sm, Tm, Yb, Lu, Y) are determined to contain 4f6 5d0 (SmII), 4f13 5d0 (TmII), 4f14 5d0 (YbII), 4f14 5d1 (LuII), and 4d1 (YII) electronic configurations. Additionally, our results suggest that Ln(C5H4SiMe3)3 1– (Ln = Pr, Nd, Gd, Tb, Dy, Ho, and Er) also contain LnII ions, but with 4fn 5d1 configurations (not 4fn+1 5d0). In these 4fn 5d1 complexes, the C 3h-symmetric ligand environment provides a highly shielded 5d-orbital of a′ symmetry that made the 4fn 5d1 electronic configurations lower in energy than the more typical 4fn+1 5d0 configuration. PMID:28989638

  15. IUPAC-NIST Solubility Data Series. 100. Rare Earth Metal Fluorides in Water and Aqueous Systems. Part 3. Heavy Lanthanides (Gd–Lu)

    Energy Technology Data Exchange (ETDEWEB)

    Mioduski, Tomasz [Institute of Nuclear Chemistry and Technology, 03195 Warszawa (Poland); Gumiński, Cezary, E-mail: [Department of Chemistry, University of Warsaw, 02093 Warszawa (Poland); Zeng, Dewen, E-mail: [College of Chemistry and Chemical Engineering, Central South University, Changsha 410083 (China)


    This is the third part of the volume devoted to solubility data for the rare earth metal (REM) fluorides in water and in aqueous ternary and multicomponent systems. It covers experimental results of trivalent fluorides of Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu (so-called heavy lanthanides), since no quantitative data on solubilities of TbF{sub 4} and YbF{sub 2} (the most stable compounds at these valencies) are available. The related literature has been covered through the end of 2014. Compilations of all available papers with the solubility data are introduced for each REM fluoride with a corresponding critical evaluation. Every such assessment contains a collection of all solubility results in aqueous solution, a selection of suggested solubility data, a solubility equation, and a brief discussion of the multicomponent systems. Only simple fluorides (no complexes or double salts) are treated as the input substances in this report. General features of the systems, such as nature of the equilibrium solid phases, solubility as a function of temperature, influence of ionic strength, solution pH, mixed solvent medium on the solubility, quality of the solubility results, and the solubility as a function of REM atomic number, have already been presented in Part 1 of the volume.

  16. IUPAC-NIST Solubility Data Series. 100. Rare Earth Metal Fluorides in Water and Aqueous Systems. Part 3. Heavy Lanthanides (Gd-Lu) (United States)

    Mioduski, Tomasz; Gumiński, Cezary; Zeng, Dewen


    This is the third part of the volume devoted to solubility data for the rare earth metal (REM) fluorides in water and in aqueous ternary and multicomponent systems. It covers experimental results of trivalent fluorides of Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu (so-called heavy lanthanides), since no quantitative data on solubilities of TbF4 and YbF2 (the most stable compounds at these valencies) are available. The related literature has been covered through the end of 2014. Compilations of all available papers with the solubility data are introduced for each REM fluoride with a corresponding critical evaluation. Every such assessment contains a collection of all solubility results in aqueous solution, a selection of suggested solubility data, a solubility equation, and a brief discussion of the multicomponent systems. Only simple fluorides (no complexes or double salts) are treated as the input substances in this report. General features of the systems, such as nature of the equilibrium solid phases, solubility as a function of temperature, influence of ionic strength, solution pH, mixed solvent medium on the solubility, quality of the solubility results, and the solubility as a function of REM atomic number, have already been presented in Part 1 of the volume.

  17. Synthesis, structural characterization and Mössbauer study of LnV{sub 0.5}Fe{sub 0.5}O{sub 3} perovskites (Ln = Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er)

    Energy Technology Data Exchange (ETDEWEB)

    Ivashita, Flávio F.; Biondo, Valdecir; Bellini, Jusmar V.; Paesano, Andrea [Departamento de Física, Universidade Estadual de Maringá, Av. Colombo 5790, 87.020-900 Maringá, PR (Brazil); Blanco, M. Cecilia; Fuertes, Valeria C.; Pannunzio-Miner, Elisa V. [INFIQC-CONICET, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba (Argentina); Carbonio, Raúl E., E-mail: [INFIQC-CONICET, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba (Argentina)


    Graphical abstract: Mössbauer spectra taken at 200 K for the Y(V{sub 0.5}Fe{sub 0.5})O{sub 3} orthoferrivanadate synthesized by arc-melting. Highlights: ► LnFe{sub 0.5}V{sub 0.5}O{sub 3} were synthesized by the first time for most of the rare-earth elements. ► These orthoferrivanadates crystallize metastably with the perovskite structure. ► Iron and vanadium are trivalent stabilized in these solid solutions. ► The Mössbauer quadrupolar splitting is correlated with the tolerance factor. ► Below 100 K, these perovskites undergo a crystallographic phase transformation. -- Abstract: Perovskites LnV{sub 0.5}Fe{sub 0.5}O{sub 3} (Ln = Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho and Er) were synthesized by rapid solidification from arc-melted samples and characterized by the study of their crystal structure and hyperfine properties. These metastable solid solutions crystallized in the Pbnm symmetry, with the iron and vanadium cations randomly distributed in the transition metal octahedral sites. Depending on the lanthanide present at the A site of the perovskite, iron is present with two valences (i.e., Fe{sup 3+} and Fe{sup 2+}). The volume of the unit cell for these perovskites increases linearly with the lanthanide ionic radius, as the perovskite approaches its ideal structure. At room temperature, the quadrupolar splitting of the trivalent paramagnetic Mössbauer component works as an indirect measurement for the Goldshmidt tolerance factor. Close to or below 100 K, these perovskites undergo a crystallographic phase transformation, probably due to orbital ordering of the V{sup 3+} cations, originating two different magnetic iron sites.

  18. In situ measurements of HO{sub x} in super- and subsonic aircraft exhaust plumes

    Energy Technology Data Exchange (ETDEWEB)

    Hanisco, T.F.; Wennberg, P.O.; Cohen, R.C.; Anderson, J.G. [Harvard Univ., Cambridge, MA (United States). Dept. of Chemistry; Fahey, D.W.; Keim, E.R.; Gao, R.S.; Wamsley, R.C.; Donnelly, S.G.; Del Negro, L.A. [National Oceanic and Atmospheric Administration, Boulder, CO (United States). Aeronomy Lab.; and others


    Concentrations of HO{sub x} (OH and HO{sub 2}) have been obtained in the exhaust plumes of an Air France Concorde and a NASA ER-2 in the lower stratosphere and the NASA DC-8 in the upper troposphere using instruments aboard the NASA ER-2. These fast-time response in situ measurements are used in conjunction with simultaneous in situ measurements of other key exhaust species (NO, NO{sub 2}, NO{sub y}, H{sub 2}O, and CO) to analyze the emissions of HO{sub x} from each aircraft under a variety of conditions. The data are used to establish a general description of gas phase plume chemistry that is easily implemented in a photochemical model. This model is used to determine the amount of HO{sub x} emitted from the engines and the gas phase oxidation rates of nitrogen and sulfur species in the exhaust plumes. (author) 10 refs.

  19. Single Longitudinal Mode, High Repetition Rate, Q-switched Ho:YLF Laser for Remote Sensing (United States)

    Bai, Yingxin; Yu, Jirong; Petzar, Paul; Petros, M.; Chen, Songsheng; Trieu, Bo; Lee, Nyung; Singh, U.


    Ho:YLF/LuLiF lasers have specific applications for remote sensing such as wind-speed measurement and carbon dioxide (CO2) concentration measurement in the atmosphere because the operating wavelength (around 2 m) is located in the eye-safe range and can be tuned to the characteristic lines of CO2 absorption and there is strong backward scattering signal from aerosol (Mie scattering). Experimentally, a diode pumped Ho:Tm:YLF laser has been successfully used as the transmitter of coherent differential absorption lidar for the measurement of with a repetition rate of 5 Hz and pulse energy of 75 mJ [1]. For highly precise CO2 measurements with coherent detection technique, a laser with high repetition rate is required to averaging out the speckle effect [2]. In addition, laser efficiency is critically important for the air/space borne lidar applications, because of the limited power supply. A diode pumped Ho:Tm:YLF laser is difficult to efficiently operate in high repetition rate due to the large heat loading and up-conversion. However, a Tm:fiber laser pumped Ho:YLF laser with low heat loading can be operated at high repetition rates efficiently [3]. No matter whether wind-speed or carbon dioxide (CO2) concentration measurement is the goal, a Ho:YLF/LuLiF laser as the transmitter should operate in a single longitudinal mode. Injection seeding is a valid technique for a Q-switched laser to obtain single longitudinal mode operation. In this paper, we will report the new results for a single longitudinal mode, high repetition rate, Q-switched Ho:YLF laser. In order to avoid spectral hole burning and make injection seeding easier, a four mirror ring cavity is designed for single longitudinal mode, high repetition rate Q-switched Ho:YLF laser. The ramp-fire technique is chosen for injection seeding.

  20. Hybrid synchronization of hyperchaotic Lu system

    Indian Academy of Sciences (India)

    In this paper, we study the hybrid synchronization between two identical hyperchaotic Lu systems. Hybrid synchronization of hyperchaotic Lu system is achieved through synchronization of two pairs of states and anti-synchronization of the other two pairs of states. Active controls are designed to achieve hybrid ...

  1. Nuclear Data Sheets for 170Lu (United States)

    Baglin, Coral M.


    Nuclear structure data pertaining to 170Lu have been compiled and evaluated, and incorporated into the ENSDF data file. This evaluation of 170Lu supersedes the previous publication (C. Baglin, Nuclear Data Sheets 77,125 (1996) (literature cutoff date October 1995)), and includes literature available by 8 Otober 1998.

  2. The rare Lu:-6 phenotype in Israel and the clinical significance of anti-Lu6. (United States)

    Yahalom, Vered; Ellis, Martin H; Poole, Joyce; Rahimi-Levene, Naomi; Shinar, Eilat; DaCosta, Yehudit; Manny, Noga; Levene, Cyril


    Lu6 is a high-incidence antigen of the Lutheran blood group. Examples of anti-Lu6 are rare and are of uncertain clinical significance. Three patients were encountered in whom anti-Lu6 was detected on pretransfusion screening. The patients were all Iranian Jews and were not known to be related. In vitro studies to ascertain the potential clinical significance of the antibody using the monocyte monolayer assay (MMA) were negative in two patients. The third patient received a two-unit transfusion of incompatible Lu6 RBCs with no signs of hemolysis. However, after the transfusion, the MMA and a chemiluminescence test were positive, whereas a chromium survival study was normal. Thus, the antibody may have changed in its clinical significance. Although anti-Lu6 does not appear to be a clinically significant RBC antibody in all circumstances, transfusion of Lu6 RBCs in patients with anti-Lu6 should be performed cautiously.

  3. An unsymmetrized multifrontal LU factorization

    Energy Technology Data Exchange (ETDEWEB)

    Amestoy, Patrick R.; Puglisi, Chiara


    A well-known approach to compute the LU factorization of a general unsymmetric matrix bf A is to build the elimination tree associated with the pattern of the symmetric matrix A + A{sup T} and use it as a computational graph to drive the numerical factorization. This approach, although very efficient on a large range of unsymmetric matrices, does not capture the unsymmetric structure of the matrices. We introduce a new algorithm which detects and exploits the structural unsymmetry of the submatrices involved during the process of the elimination tree. We show that with the new algorithm significant gains both in memory and in time to perform the factorization can be obtained.

  4. LiHo(PO34

    Directory of Open Access Journals (Sweden)

    Mokhtar Férid


    Full Text Available Lithium holmium(III polyphosphate(V, LiHo(PO34, belongs to the type I of polyphosphates with general formula ALn(PO34, where A is a monovalent cation and Ln is a trivalent rare earth cation. In the crystal structure, the polyphosphate chains spread along the b-axis direction, with a repeat period of four tetrahedra and 21 internal symmetry. The Li and Ho atoms are both located on twofold rotation axes and are surrounded by four and eight O atoms, leading to a distorted tetrahedral and dodecahedral coordination, respectively. The HoO8 polyhedra are isolated from each other, the closest Ho...Ho distance being 5.570 (1 Å.

  5. Afnám einkasölu áfengis. Yfirlit yfir rannsóknir á breytingum á áfengissölu

    Directory of Open Access Journals (Sweden)

    Hildigunnur Ólafsdóttir


    Full Text Available Í skýrslunni er gerð grein fyrir helstu rannsóknum sem gerðar hafa verið á breytingum á áfengiseinkasölu og aðgengi áfengis. Rannsóknir á breyttu fyrirkomulagi áfengissölu eru flestar frá Norður-Ameríku og Norðurlöndunum. Nær allar rannsóknirnar sýna að í kjölfar einkavæðingar á áfengissölu hefur áfengisneysla aukist. Ennfremur er greint frá rannsóknum á breytingum á áfengissköttum, sem leiða í ljós að lækkun þeirra eykur áfengisneyslu og tjón af völdum áfengis. Stuttlega er fjallað um rannsóknir á áfengiskaupaaldri, á reglum um áfengisauglýsingar og viðvörunarmerkingar á áfengi. Til þess að setja þessa þætti áfengisstefnunnar í víðara samhengi er gerð grein fyrir norrænu samstarfi um áfengismál á alþjóðlegum vettvangi og stöðu áfengismála hjá Alþjóðaheilbrigðismálastofnuninni og Evrópusambandinu. Greint er frá því að innan Alþjóðaheilbrigðismálastofnunarinnar er stefnt að samþykkt um áfengismál, sem verði baráttutæki gegn áfengisvandamálum. Þá er sagt frá stefnuskjali Evrópusambandsins og stofnun The European Alcohol and Health Forum, sem innan tíðar mun leggja fram aðgerðaáætlun til þess að vernda íbúa Evrópu gegn skaðlegri neyslu áfengis.

  6. lu defragmenteerimine / Ilja Sundelevitsh

    Index Scriptorium Estoniae

    Sundelevitsh, Ilja


    Viktor Misiano kureeritud projekt "Mälu tagasitulek" Kumu Kunstimuuseumis kuni 29. VII. Dmitri Gutovi projektist, mis koosneb videotest "Sula" ja "Kajakad" ning kolmest maalist, Valentin Arhipovi projektist "Vassili Grigorjevitsh Arhipovi looming aastail 1962-2006", Juri Leidermani heliinstallatsioonist "Isa jutustus", Jevgeni Fiksi projektist, Gljuklja & Tzaplja (Olga Jegorova, Natalja Pershina) installatsioonist "Punased purjed", Igor Shtsherbini tööst "Defragmenteerimine. Stirlitzi mälu" ja Sergei Bratkovi tööst

  7. Electrical transport and magnetic ordering in R2Ti3Ge4 (R = Dy, Ho ...

    Indian Academy of Sciences (India)

    Abstract. New R2Ti3Ge4 (R = Dy, Ho and Er) intermetallic compounds have been synthesized and characterized by X-ray diffraction and low temperature ac magnetic susceptibility, electrical re- sistivity and thermoelectric power measurements were carried out. The compounds crystallize in the parent, Sm5Ge4-type ...

  8. Heme Degradation by Heme Oxygenase Protects Mitochondria but Induces ER Stress via Formed Bilirubin

    Directory of Open Access Journals (Sweden)

    Andrea Müllebner


    Full Text Available Heme oxygenase (HO, in conjunction with biliverdin reductase, degrades heme to carbon monoxide, ferrous iron and bilirubin (BR; the latter is a potent antioxidant. The induced isoform HO-1 has evoked intense research interest, especially because it manifests anti-inflammatory and anti-apoptotic effects relieving acute cell stress. The mechanisms by which HO mediates the described effects are not completely clear. However, the degradation of heme, a strong pro-oxidant, and the generation of BR are considered to play key roles. The aim of this study was to determine the effects of BR on vital functions of hepatocytes focusing on mitochondria and the endoplasmic reticulum (ER. The affinity of BR to proteins is a known challenge for its exact quantification. We consider two major consequences of this affinity, namely possible analytical errors in the determination of HO activity, and biological effects of BR due to direct interaction with protein function. In order to overcome analytical bias we applied a polynomial correction accounting for the loss of BR due to its adsorption to proteins. To identify potential intracellular targets of BR we used an in vitro approach involving hepatocytes and isolated mitochondria. After verification that the hepatocytes possess HO activity at a similar level as liver tissue by using our improved post-extraction spectroscopic assay, we elucidated the effects of increased HO activity and the formed BR on mitochondrial function and the ER stress response. Our data show that BR may compromise cellular metabolism and proliferation via induction of ER stress. ER and mitochondria respond differently to elevated levels of BR and HO-activity. Mitochondria are susceptible to hemin, but active HO protects them against hemin-induced toxicity. BR at slightly elevated levels induces a stress response at the ER, resulting in a decreased proliferative and metabolic activity of hepatocytes. However, the proteins that are targeted

  9. Radiation hardness of LuAG:Ce and LuAG:Pr scintillator crystals

    CERN Document Server

    Derdzyan, M V; Belsky, A; Dujardin, C; Lecoq, P; Lucchini, M; Ovanesyan, K L; Pauwels, K; Pedrini, C; Petrosyan, A G


    Single crystals of LuAG:Ce, LuAG:Pr and un-doped LuAG were grown by the vertical Bridgman method and studied for radiation hardness under gamma-rays with doses in the range 10-10(5) Gy (Co-60). A wide absorption band peaking at around 600 nm springs up in all three types of crystals after the irradiations. The second band peaking at around 375 nm appears in both LuAG:Pr and un-doped LuAG. Compositional variations have been done to reveal the spectral behavior of induced color centers in more detail and to understand their origin. Similarities in behavior of Yb2+ centers in as-grown garnets are found, indicating that radiation induced color centers can be associated with residual trace amounts of Yb present in the raw materials. Un-doped LuAG and LuAG:Ce demonstrate moderate radiation hardness (the induced absorption coefficients being equal to 0.05-0.08 cm(-1) for accumulated doses of 10(3)-10(4) Gy), while LuAG:Pr is less radiation hard. The ways to improve the radiation hardness are discussed.

  10. NdHO, a novel oxyhydride

    DEFF Research Database (Denmark)

    Widerøe, Marius; Fjellvåg, Helmer; Norby, Truls


    A new metal oxyhydride; neodymium oxyhydride, NdHO, has been synthesized from a reactant mixture of metal hydride (CaH2 or NdH3) and neodymium oxide(Nd2O3). The unit cell dimensions decrease smoothly in the series from LaHO, CeHO, PrHO to NdHO, in line with the lanthanide contraction. The crystal...

  11. Temperature Dependent Local Atomic Structure of LuFe2O4 (United States)

    Liu, S.; Zhang, H.; Ghose, S.; Cheong, S.-W.; Emge, T.; Chen, Y.-S.; Tyson, T.

    The LuFe2O4 system has be studied intensively as a novel material with charge ordered driven ferroelectricity. However, the existence and origin of electric polarization and it coupling to the magnetic structure are open questions still to be addressed. Distinctly differing experiments yield different results. In this work, structural measurements on multiple length scales have been conducted over a broad range of temperatures. We have studied the correlation between the structural distortion and the electronic/magnetic properties in single-crystalline LuFe2O4 by using X-ray diffraction (XRD), temperature and orientation dependent Raman spectroscopy, temperature dependent X-ray pair distribution function (PDF) measurements and DFT modeling. The nature of the observed local atomic and electronic structural changes will be discussed and compared with previous work. This work is supported by DOE Grant DE-FG02-07ER46402.

  12. Heme oxygenase (HO)-1 induction prevents Endoplasmic Reticulum stress-mediated endothelial cell death and impaired angiogenic capacity. (United States)

    Maamoun, Hatem; Zachariah, Matshediso; McVey, John H; Green, Fiona R; Agouni, Abdelali


    Most of diabetic cardiovascular complications are attributed to endothelial dysfunction and impaired angiogenesis. Endoplasmic Reticulum (ER) and oxidative stresses were shown to play a pivotal role in the development of endothelial dysfunction in diabetes. Hemeoxygenase-1 (HO-1) was shown to protect against oxidative stress in diabetes; however, its role in alleviating ER stress-induced endothelial dysfunction remains not fully elucidated. We aim here to test the protective role of HO-1 against high glucose-mediated ER stress and endothelial dysfunction and understand the underlying mechanisms with special emphasis on oxidative stress, inflammation and cell death. Human Umbilical Vein Endothelial Cells (HUVECs) were grown in either physiological or intermittent high concentrations of glucose for 5days in the presence or absence of Cobalt (III) Protoporphyrin IX chloride (CoPP, HO-1 inducer) or 4-Phenyl Butyric Acid (PBA, ER stress inhibitor). Using an integrated cellular and molecular approach, we then assessed ER stress and inflammatory responses, in addition to apoptosis and angiogenic capacity in these cells. Our results show that HO-1 induction prevented high glucose-mediated increase of mRNA and protein expression of key ER stress markers. Cells incubated with high glucose exhibited high levels of oxidative stress, activation of major inflammatory and apoptotic responses [nuclear factor (NF)-κB and c-Jun N-terminal kinase (JNK)] and increased rate of apoptosis; however, cells pre-treated with CoPP or PBA were fully protected. In addition, high glucose enhanced caspases 3 and 7 cleavage and activity and augmented cleaved poly ADP ribose polymerase (PARP) expression whereas HO-1 induction prevented these effects. Finally, HO-1 induction and ER stress inhibition prevented high glucose-induced reduction in NO release and impaired the angiogenic capacity of HUVECs, and enhanced vascular endothelial growth factor (VEGF)-A expression. Altogether, we show here the

  13. Sulfide iodides (MSI) of the heavier lanthanoids (M = Gd - Lu). Crystal structures and magnetic properties; Sulfidiodide (MSI) der schweren Lanthanoide (M = Gd - Lu). Kristallstrukturen und magnetische Eigenschaften

    Energy Technology Data Exchange (ETDEWEB)

    Blaschkowski, Bjoern; Schleid, Thomas [Institut fuer Anorganische Chemie, Universitaet Stuttgart (Germany); Rosner, Helge; Schnelle, Walter [Max-Planck-Institut fuer Chemische Physik fester Stoffe, Dresden (Germany)


    From reactions of equimolar quantities of the heavier lanthanoids (M = Gd - Lu) with the elements sulfur and iodine in fused silica ampoules (900 C, 10 d) phase-pure samples of the lanthanoid sulfide iodides MSI (M = Gd - Lu) could be prepared. Besides the already structurally determined sulfide iodides MSI with M = Gd and Dy, all samples could be characterized by means of X-ray powder diffraction and their magnetic behavior was examined. In addition a single-crystal structure refinement for HoSI was carried out (orthorhombic, Pmmn; a = 415.09(4) pm, b = 531.34(5) pm, c = 920.53(9) pm), which confirmed the isotypy of the later lanthanoid sulfide iodides with the structure of FeOCl. On the basis of the X-ray powder diffraction experiments all prepared compounds could be indexed in a primitive orthorhombic unit cell. An analysis of the determined lattice parameters and cell volumes resulted in the typical lanthanoid contraction for compounds within the row of the 4f elements. The magnetochemical studies led to the expected effective magnetic moments for trivalent lanthanoid cations without showing any magnetic ordering phenomenon. (Copyright copyright 2013 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  14. Souvislosti pracovního kapitálu s podnikovou výkonností


    BALLÁKOVÁ, Monika


    The aim of the Diploma work was to evaluate the evolution of the structure of working capital in connection with corporate efficiency in a particular company for the period 2008 - 2011. In the theoretical part was at first described working capital, methods of efficiency evaluation. The practical part begins to describe a company Zemědělské družstvo Netřebice, followed by analysis of the company itself. The results are compared with previous years and some with industry.

  15. Suppression of impurity phases and the study of magnetic and magnetocaloric properties of Ho2Co2Al intermetallic compound (United States)

    Balfour, E. A.; Shang, Y. F.; Fu, H.; El-Gendy, Ahmed A.; Hadimani, R. L.; Luo, Y.


    The R2Co2Al compounds (R = Tb, Dy, Ho, Er, Tm) are known to contain RCoAl-type impurity. In order to suppress the impurity phase in Ho2Co2Al intermetallic compound, nonstoichiometric samples with excess rare-earth Ho were prepared and annealed. Structural analysis indicates that annealed nonstoichiometric Ho42Co40Al20 sample, with 2 at% excess Ho, comprises the Ho2Co2Al phase and minor traces of Ho2O3 oxide. Magnetic and magnetocaloric properties of the sample have been studied in detail. The alloy undergoes three phase transitions at 9 K, 21 K and 30 K. The multiple transitions and broadening effect of second-order phase transitions (SOT) on peak magnetic entropy change (-ΔSM), result in good refrigerant capacities (RCareas) of 136.9 and 437 J/kg under field changes (ΔH) of 2 and 5 T, respectively. These values of RCarea and their corresponding large -ΔSM peak magnitudes of 9.1 and 18.4 J/kg K under ΔH = 2 and 5 T, respectively, make Ho2Co2Al a promising and competitively good candidate magnetic refrigerant for low temperature cooling applications such as liquefaction of hydrogen gas.

  16. Spectral properties of hydrothermally-grown Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3} laser materials

    Energy Technology Data Exchange (ETDEWEB)

    Brown, David C., E-mail: [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States); McMillen, Colin D.; Moore, Cheryl; Kolis, Joseph W. [Department of Chemistry and Center for Optical Materials Science and Engineering Technologies, Clemson University, Clemson, SC 29634-0973 (United States); Envid, Victoria [Snake Creek Lasers LLC, Friendsville, PA 18818 (United States)


    We have investigated the hydrothermal growth of, and spectrally characterized, the lutetium based laser materials Nd:LuAG, Yb:LuAG, and Yb:Lu{sub 2}O{sub 3}. Absorption cross-section data are presented for Nd:LuAG at 83, 175, and 295 K. Absorption cross-section data was also obtained for Yb:LuAG at 83, 175, and 295 K; the 295 K data was used to generate emission cross-sections using the method of reciprocity. For Yb:Lu{sub 2}O{sub 3}, we present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity. -- Highlights: • We present spectral properties for hydrothermally-grown laser crystals. • Absorption cross-section data are presented for Nd:LuAG and Yb:LuAG at 83, 175, and 295 K. • Emission cross-sections are presented for Yb:LuAG at 295 K derived by reciprocity. • We present absorption cross-sections at 295 K as well as emission cross-sections derived using reciprocity for the laser material Yb:Lu{sub 2}O{sub 3}.

  17. lu, kallis vara / Peeter Maimik

    Index Scriptorium Estoniae

    Maimik, Peeter, 1944-2010


    Poola ohvitseride mõrvamisest NKVD poolt 1940. aastal Katõnis, Andrzej Wajda selleteemalisest filmist "Katõn" ja ajaloolise mälu säilitamise olulisusest. Inimsusevastaste kuritegude uurimise rahvusvahelise komisjoni uurimistööst, mis käsitleb Saksa ja Nõukogude okupatsioone Eestis

  18. LU factorization for accelerator-based systems

    KAUST Repository

    Agullo, Emmanuel


    Multicore architectures enhanced with multiple GPUs are likely to become mainstream High Performance Computing (HPC) platforms in a near future. In this paper, we present the design and implementation of an LU factorization using tile algorithm that can fully exploit the potential of such platforms in spite of their complexity. We use a methodology derived from previous work on Cholesky and QR factorizations. Our contributions essentially consist of providing new CPU/GPU hybrid LU kernels, studying the impact on performance of the looking variants as well as the storage layout in presence of pivoting, tuning the kernels for two different machines composed of multiple recent NVIDIA Tesla S1070 (four GPUs total) and Fermi-based S2050 GPUs (three GPUs total), respectively. The hybrid tile LU asymptotically achieves 1 Tflop/s in single precision on both hardwares. The performance in double precision arithmetic reaches 500 Gflop/s on the Fermi-based system, twice faster than the old GPU generation of Tesla S1070. We also discuss the impact of the number of tiles on the numerical stability. We show that the numerical results of the tile LU factorization will be accurate enough for most applications as long as the computations are performed in double precision arithmetic. © 2011 IEEE.


    African Journals Online (AJOL)

    In this paper, we propose a straightforward method based on multipliers derived from modification of. Gaussion elimination algorithm. KEY WORDS: Lower and Upper Triangular Matrices, Multipliers. INTRODUCTION. Let A be a square matrix of order n. An LU factorization or decomposition is a decomposition of the form:.

  20. Návrh konstrukce zadního nárazníku osobního vozidla


    Tomeš, Jan


    Bakalářská práce se zabývá rešerší problematiky nárazníků osobních automobilů. Soustředí se především na nárazové testy RCAR a v současnosti používané konstrukce nárazníků osobních vozidel. Na základě poznatků z rešerše je navrhován koncept zadního nárazníku k designové studii vozu firmy Swell. The Bachelor thesis deals with search about passenger car bumpers. It focuses especially on RCAR crash tests and currently used constructions of bumpers. There is suggested concept of rear bumper ba...

  1. Hvem er vi? Hvem er de?

    DEFF Research Database (Denmark)

    Kryger, Niels


    Kommentaren tager afsæt i initiativer i de pædagogiske faglige foreninger i Europa EERA) og i Norden (NERA) og argumenterer for at det er forpligtelse for os som nordiske og europæiske pædagogiske forskere at gå op imod de stadigt mere ekskluderende vi-konstruktioner, som er blevet formuleret i for...

  2. Separation and implantation of the rare isotope {sup 163}Ho

    Energy Technology Data Exchange (ETDEWEB)

    Kieck, Tom; Chrysalidis, Katerina; Dorrer, Holger; Kormannshaus, Stefan; Schmidt, Sebastian; Schneider, Fabian; Wendt, Klaus [JGU Mainz (Germany); Duellmann, Christoph [JGU Mainz (Germany); GSI Darmstadt (Germany); Gamer, Lisa; Gastaldo, Loredana [Universitaet Heidelberg (Germany); Collaboration: ECHo-Collaboration


    The ECHo collaboration aims at measuring the electron neutrino mass by recording the spectrum following electron capture of {sup 163}Ho. To reach a sub-eV sensitivity, a large number of individual microcalorimeters is needed, into which the isotope must be implanted in a well-controlled manner. The necessary amount of {sup 163}Ho is produced by neutron irradiation of enriched {sup 162}Er in the ILL high flux reactor. This introduces significant contaminations of other radioisotopes, which have to be quantitatively removed both, by chemical and mass spectrometric separation. The application of resonance ionization at the RISIKO mass separator guarantees the required isotope selectivity for purification and suitable energy for ion implantation. The efficiency and stability of the laser ion source was improved by Finite-Element Analysis of the thermal processes. For optimum implantation into the detector pixels (170 x 170 μm{sup 2}) with minimum losses a small ion beam spot at the implantation site is needed. For this purpose, post focusing ion optics were installed. Simulations were performed in order to optimize the homogeneous distribution of the implanted ions. The necessity to alternate implantation phases with deposition of a thin metallic layer for {sup 163}Ho activities larger than 10 Bq is being discussed.

  3. Optimization of loading ratio of ErN as regenerator of 4K-GM cryocooler (United States)

    Nakagawa, T.; Miyauchi, T.; Shiraishi, T.; Seino, S.; Yamamoto, T. A.; Fujimoto, Y.; Masuyama, S.


    High purity erbium nitride (ErN) spheres with the size range of 150-180 µm and 180-212 µm were prepared by nitriding Er metal spheres with low oxygen content. The initial regenerator material of HoCu2 on the cold end of the second regenerator column in 4K-GM cryocooler with nominal cooling power of 0.1 W at 4.2 K was replaced by ErN with different sizes. Higher cooling power was obtained when ErN of smaller size with lower oxygen content was used. We investigated the effect of partial replacement of HoCu2 by ErN in the cold end side of second stage regenerator column on cooling power of 4K-GM cryocoolers. When ErN were substituted for 20 % of HoCu2, the cooling power at 4.2 K reached 0.318 W. This value was 1.36 times as high as that of the cooling power of the GM cryocooler with commercially available regenerator arrangement. Therefore, use of ErN regenerator materials leads to the energy-saving and downsizing of 4K-GM cryocoolers.

  4. Properties of LuAP: CE scintillator containing intentional impurities

    CERN Document Server

    Petrosyan, A G; Ovanesyan, K; Lecoq, Paul; Auffray, Etiennette; Trummer, Julia; Kronberger, Matthias; Pédrini, C; Dujardin, C; Anfre, P


    Single crystals of LuAP:Ce and LuYAP(Lu*70%):Ce co-doped with tetravalent (Hf and Zr) and pentavalent (Ta) ions were grown from melts by the Bridgman process. Underlying absorption, slope of the optical edge and transmission in the range of emission were compared to those of LuAP:Ce crystals. Absorption coefficients at 260 nm less than 2 cm−1 have been recorded in LuAP:Ce crystals containing tetravalent ions that are lower than the corresponding figures (5–6 cm−1) measured in undoped LuAP. At high concentrations of added impurities, despite of suppression of the parasitic underlying absorption below 300 nm, the slope of the optical edge and transmission in the range of emission are seriously damaged. Scintillation parameters of crystals with added impurities are compared to those of LuAP:Ce.

  5. Puf er plat

    DEFF Research Database (Denmark)

    Hansen, Pelle Guldborg; Zeller, Clara


    Der er stort set ingen, der har fattet, hvad nudging egentlig er. Et nudge er nemlig hverken ”et lille blidt skub”, eller ”en helt ny videnskabelig metode [der] kan ændre vores adfærd, uden vi opdager det - og uden det koster os noget”, ligesom det heller ikke er ”en måde at friste kunder til at ...

  6. Demokratiets krise er lovende

    DEFF Research Database (Denmark)

    Thomassen, Bjørn; Harrebye, Silas Fehmerling


    Demokratiet er i krise. Men den er langtfra bundløs. For når eksisterende partier, traditionelle virksomheder, den velkendte fagforening og de gamle medier udfordres, opstår muligheden for et sceneskift. Meget peger på, at det er på vej...

  7. Thermodynamic and transport properties of RSn{sub 2} (R=Tb–Tm, Lu, Y) single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Liang L., E-mail: [Department of Physics and Astronomy, Rice University, Houston, TX 77005 (United States); Mehlman, Michael S. [Department of Physics and Astronomy, Rice University, Houston, TX 77005 (United States); Besara, Tiglet; Siegrist, Theo [Department of Chemical and Biomedical Engineering, Florida State University and National High Magnetic Field Laboratory, Tallahassee, FL 32310 (United States); Morosan, E. [Department of Physics and Astronomy, Rice University, Houston, TX 77005 (United States)


    We report the anisotropic magnetization, heat capacity and resistivity measurements for isostructural RSn{sub 2} (R=Tb–Tm, Lu, Y) single crystals. The R=Tb–Tm compounds exhibit long range antiferromagnetic ordering with T{sub N} ranging from 26.3 K to 3.6 K. An additional incommensurate-to-commensurate transition at a lower critical temperature T{sub 1} is observed for R=Tb–Ho. Field-induced metamagnetic transitions have also been observed for all magnetic rare earth compounds. The resistivity has a typical metallic character with a relatively high residual resistivity ratio. Both the AFM ordering temperature and spin disordered resistivity scale with the de Gennes factor. The magnetic heat capacity data indicate partially lifted ground state degeneracies associated with crystal electric field splitting. - Highlights: • We report thermodynamic and transport properties of RSn{sub 2} (R=Tb–Tm, Lu, Y) single crystals. • RSn{sub 2} compounds with R=Tb–Tm exhibit AFM ordering and metamagnetic transitions. • An incommensurate to commensurate transition has been observed for R=Tb–Ho. • The ordering temperature and spin disorder resistivity scale well with the de Gennes factor. • Magnetic heat capacity reveals partially lifted ground state degeneracy.

  8. A Stability Analysis of Incomplete LU Factorizations. (United States)


    LU factorization ( MILU ) [5, 11], each of which makes use of an approximate factorization of the coefficient matrix into the product of a sparse lower...discretization of self-adjoint elliptic problems on a uniform n x n grid, it is known that the MILU preconditioning produces a reduction of the the mesh points. In particular, a heuristic explanation of the difference between the MILU and ILU factorizations is that the individual entries of

  9. Recursive Approach in Sparse Matrix LU Factorization

    Directory of Open Access Journals (Sweden)

    Jack Dongarra


    Full Text Available This paper describes a recursive method for the LU factorization of sparse matrices. The recursive formulation of common linear algebra codes has been proven very successful in dense matrix computations. An extension of the recursive technique for sparse matrices is presented. Performance results given here show that the recursive approach may perform comparable to leading software packages for sparse matrix factorization in terms of execution time, memory usage, and error estimates of the solution.

  10. Oligocene-Early Miocene Planktonic Microbiostratigraphy and Paleoenvironments of the South Slovakian Basin (Lučenec Depression) (United States)

    Ozdínová, Silvia; Soták, Ján


    Oligocene and Lower Miocene sediments of the Lučenec Depression were studied to demonstrate the planktonic bioevents and climatic proxies from the Číž Formation (Rupelian) and Lučenec Formation (Chattian-Aquitanian) on the basis of quantitative analyses of foraminifers and calcareous nannofossils. The oldest nannofossil assemblages of the Číž Formation belonged to the NP23 Zone and were dominated by Reticulofenestra ornata known for preference of temperate eutrophic water conditions. An increase in bioproductivity was documented by abundant large-sized planktonic foraminifers (e.g. Turborotalia ampliapertura, Paragloborotalia nana, Subbotina gortanii) and epifaunal to shal-low-infaunal benthic species. The middle part of the Číž Formation reveals a lowstand progradation of deltaic sediments of the Rapovce Member. There, the planktonic foraminifers are impoverished in both size and diversity, containing mostly tenuitellid and cassigerinellid species, probably as a result of decreased salinity and increased anoxia in the Tard Clay. Contrary of this, the benthic foraminifers are rich, mainly the infaunal forms of uvigerinid species. They probably proliferated due to a high organic flux from riverine input. Open marine conditions were restored in the upper part of the Číž Formation above the lowest occurrence (LO) of Cyclicargolithus abisectus on the NP23-NP24 zone boundary. The transitional interval between the Číž and Lučenec formations (O5/O6 - NP24/25) was approximated by the HOs of Paragloborotalia opima and Sphenolithus distentus and the LOs of Globigerinoides primordius and Pontosphaera enormis. Benthic foraminifera of the Lučenec Formation indicate a high productivity and oxygen-deplected environ-ments. The Oligocene-Miocene boundary in the Lučenec Formation was appointed by the HOs of Helicospahera recta and Dictyococcites bisectus. Foraminiferal markers of this boundary were established from the HO of Globigerina ciperoensis and the LO of

  11. Výroba součásti z plechu s využitím technologie hlubokého tažení


    Jurča, Jan


    JURČA Jan: Výroba součásti z plechu s využitím technologie hlubokého tažení. Závěrečná práce magisterského studia, 5.roč., ak. rok 2008/2009, ústav strojírenské technologie, odbor technologie obrábění, FSI VUT Brno. Práce se zabývá návrhem výroby dílu karoserie pátých dveří u automobilu pomocí technologie hlubokého tažení. Materiál zvolený na výrobu dílu je pozinkovaný plech HX220YD EN 10292. Mechanické vlastnosti a vhodnost materiálu jsou ověřeny pomocí mechanických zkoušek. Struktura materi...

  12. Low-pressure study of the HO2 + HO2 reaction at 298 K (United States)

    Sander, S. P.


    The rate constant for the reaction HO2 + HO2 yields H2O2 + O2 was measured at 298 K and 1 torr total pressure of helium by using the discharge flow technique. A quadrupole mass spectrometer was used to detect HO2 in conjunction with in situ long-path ultraviolet absorption which was used for calibration. A value of 1.5 + or - 0.4 x 10 to the -12th per molecule/s was obtained for k1 where the rate constant is defined by the relation -d(HO2)/dt = 2K1(HO2)HO2.

  13. Preparation and Preliminary Biological Evaluation of 177Lu Labelled Rituximab

    Directory of Open Access Journals (Sweden)

    MA Xiu-feng1;ZHANG Jun-li2;LI Hong-yu1,2;LIANG Ji-xin1;YANG Yun2;YANG Chun-hui2;DU Jin1,3


    Full Text Available For evaluating whether 177Lu-Rituximab could be applied for radioimmunoimaging and radioimmunotherrapy of non-Hodgkin’s Lymphoma, Rituximab, a specific chimeric monoclonal antibody used in CD20-positive B-cell Non-Hodgkin’s Lymphoma, was conjugated to bifunctional chelating agents (CHX-A''-DTPA and p-SCN-Bz-DTPA and radiolabelled with 177Lu successively. 177Lu-CHX-A''-DTPA-Rituximab and 177Lu-p-SCN-Bz-DTPA-Rituximab were obtained with labelling yield and radiochemical purity higher than 99% at optimized conditions, and showed good in vitro stability in different testing system at room temperature and 37 ℃. However, the results of biodistribution in normal mice showed high uptakes in bone which indicated that 177Lu released from the radiolabelled antibodies. The retention of free 177Lu in the bone was lower for 177Lu-p-SCN-Bz-DTPA-Rituximab compared with 177Lu-CHX-A''-DTPA-Rituximab. Our preliminary work demonstrated that p-SCN-Bz-DTPA may be more suitable for 177Lu labelling of monoclonal antibodies.

  14. SuperLU users' guide

    Energy Technology Data Exchange (ETDEWEB)

    Demmel, James W.; Gilbert, John R.; Li, Xiaoye S.


    This document describes a collection of three related ANSI C subroutine libraries for solving sparse linear systems of equations AX = B: Here A is a square, nonsingular, n x n sparse matrix, and X and B are dense n x nrhs matrices, where nrhs is the number of right-hand sides and solution vectors. Matrix A need not be symmetric or definite; indeed, SuperLU is particularly appropriate for matrices with very unsymmetric structure. All three libraries use variations of Gaussian elimination optimized to take advantage both of sparsity and the computer architecture, in particular memory hierarchies (caches) and parallelism.

  15. Výroba krytu řemenového převodu


    Rösner, Michal


    Diplomová práce předkládá návrh výroby krytu řemenového převodu z materiálu s označením dle ČSN 411320.21, o tloušťce 1,5 mm v sérii 10 000 kusů. Na základě způsobu výroby součásti je v práci představena problematika tažení, parametry, používané stroje spolu s konstrukcí nástrojů. Pro operaci hlubokého tažení byly provedeny kontrolní, technologické výpočty, vybrán hydraulický lis CTH 250, navržena sestava tažného nástroje, simulace v programu AutoForm, zpracované technicko-ekonomické zhodnoce...

  16. Vreden er over os

    DEFF Research Database (Denmark)

    Mehlsen, Camilla


    Urolige elever, cyklister - der giver fuck-finger, aggressive demonstranter. Samtiden er på vej ind i en æra domineret af vrede, siger rektor Lars-Henrik Schmidt, der er aktuel med bogen 'Om vreden'. Udgivelsesdato: Juni...

  17. Holmium dodecaiodidoiron-octahedro-hexaholmium, {FeHo6}I12Ho

    Directory of Open Access Journals (Sweden)

    Gerd Meyer


    Full Text Available Single crystals of {FeHo6}I12Ho were obtained during the reaction of HoI3 with metallic holmium and iron in a sealed tantalum container. The crystal structure consists of isolated holmium clusters encapsulating a single Fe atom, {FeHo6} (overline{3} symmetry. The rare earth metal atoms are surrounded by 12 edge-capping and six terminal iodide ligands that either connect the clusters to each other directly or via HoI6 octahedra (overline{3} symmetry.

  18. Neutron capture reactions on Lu isotopes at DANCE

    CERN Document Server

    Roig, O


    The DANCE (Detector for Advanced Neutron Capture Experiments) array located at the Los Alamos national laboratory has been used to obtain the neutron capture cross sections for 175Lu and 176Lu with neutron energies from thermal up to 100 keV. Both isotopes are of current interest for the nucleosynthesis s-process in astrophysics and for applications as in reactor physics or in nuclear medicine. Three targets were used to perform these measurements. One was natLu foil and the other two were isotope-enriched targets of 175Lu and 176Lu. The cross sections are obtained for now through a precise neutron flux determination and a normalization at the thermal neutron cross section value. A comparison with the recent experimental data and the evaluated data of ENDF/B-VII.0 will be presented. In addition, resonances parameters and spin assignments for some resonances will be featured.

  19. Ho

    Indian Academy of Sciences (India)

    Projects under Scientific and Technological planning of the education office, Jiangxi Province (GCJ2011-243), domestic visiting scholar of Jiangxi provincial higher education insti- tution, Jiangxi Province Training Programs of Innovation and. Entrepreneurship for Undergraduates (201310407028), the. Science Program of ...

  20. Hvor anvendelig er PKI?


    Nielsen, Jon Magne


    Denne oppgaven ser på bruken av elektronisk ID i statlige etater i Norge i dag. Det ses spesielt på om bruken av tekologien PKI er en god løsning på etatenes behov på dette området. Som utgangspunkt for analysen er det sett spesielt på to statlige etater. Disse etatenes behov og bruk av elektronisk ID generelt og PKI spesielt blir undersøkt. Det er videre gjort rede for hvilke lover, forskrifter og andre førende dokumenter som danner de formelle rammebetingelsene for etaters bruk av PKI. ...

  1. Laser ablation production of Ba, Ca, Dy, Er, La, Lu, and Yb ions

    CERN Document Server

    Olmschenk, S


    We use a pulsed nitrogen laser to produce atomic ions by laser ablation, measuring the relative ion yield for several elements, including some that have only recently been proposed for use in cold trapped ion experiments. For barium, we monitor the ion yield as a function of the number of applied ablation pulses for different substrates. We also investigate the ion production as a function of the pulse energy, and the efficiency of loading an ion trap as a function of radiofrequency voltage.

  2. Thermochemistry of HO2 + HO2 → H2O4: Does HO2 Dimerization Affect Laboratory Studies? (United States)

    Sprague, Matthew K; Irikura, Karl K


    Self-reaction is an important sink for the hydroperoxy radical (HO2) in the atmosphere. It has been suggested (Denis, P. A.; Ornellas, F. R. J. Phys. Chem. A, 2009, 113 (2), 499-506) that the minor product hydrogen tetroxide (HO4H) may act as a reservoir of HO2. Here, we compute the thermochemistry of HO2 self-reactions to determine if either HO4H or the cyclic hydrogen-bound dimer (HO2)2 can act as reservoirs. We computed electronic energies using coupled-cluster calculations in the complete basis set limit, CCSD(T)/CBS[45]//CCSD(T)/cc-pVTZ. Our model chemistry includes corrections for vibrational anharmonicity in the zero-point energy and vibrational partition functions, core-valence correlation, scalar relativistic effects, diagonal Born-Oppenheimer, spin-orbit splitting, and higher-order corrections. We compute the Gibbs energy of dimerization to be (-20.1 ± 1.6) kJ/mol at 298.15 K (2σ uncertainty), and (-32.3 ± 1.5) kJ/mol at 220 K. For atmospherically relevant [HO2] = 10(8) molecules per cm(3), our thermochemistry indicates that dimerization will be negligible, and thus H2O4 species are atmospherically unimportant. Under conditions used in laboratory experiments ([HO2] > 10(12) molecules per cm(3), 220 K), H2O4 formation may be significant. We compute two absorption spectra that could be used for laboratory detection of HO4H: the OH stretch overtone (near-IR) and electronic (UV) spectra.

  3. Metabolomics er fremtiden

    DEFF Research Database (Denmark)

    Pedersern, Birger


    Forskningen i fødevarer har fået et potent redskab i hånden. Metabolomics er vejen frem, mener professor Søren Balling Engelsen fra Københavns Universitet......Forskningen i fødevarer har fået et potent redskab i hånden. Metabolomics er vejen frem, mener professor Søren Balling Engelsen fra Københavns Universitet...

  4. Pseudo-spin band in the odd-odd nucleus {sup 172}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Venkova, T. [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Institute of Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, BG-1784, Sofia (Bulgaria); Lieder, R.M.; Gast, W.; Podsvirova, E.; Jaeger, H.M.; Mihailescu, L. [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Bazzacco, D.; Menegazzo, R.; Lunardi, S.; Alvarez, C. Rossi; Ur, C.; Martinez, T. [Dipartimento di Fisica dell' Universita and Istituto Nazionale di Fisica Nucleare, Sezione di Padova, I-35131, Padova (Italy); Angelis, G. de; Axiotis, M.; Napoli, D. [Laboratori Nazionali di Legnaro, Istituto Nazionale di Fisica Nucleare, I-35020, Legnaro (Italy); Urban, W.; Rzaca-Urban, T. [Institute of Experimental Physics, University of Warsaw, PL-00-681, Warszawa (Poland); Frauendorf, S. [Department of Physics, University of Notre Dame, Notre Dame, IN (United States)


    High-spin states in the odd-odd nucleus {sup 172}Lu have been populated in a {sup 170}Er({sup 7}Li,5n) reaction and the emitted {gamma}-radiation was detected with the GASP array. Two sequences of a new identical band have been observed with the transition energies in the favoured and unfavoured sequences being identical within {approx}3 keV at low spins and {approx}1 keV at high spins over the whole observed spin range. An interpretation as a pseudo-spin singlet band of {pi}1/2{sup -} [541] x {nu}1/2{sup -} [420] configuration is proposed. It represents the best example of a pseudo-spin singlet band in normal deformed nuclei known until now. (orig.)

  5. Ho:YLF pumped HBr laser. (United States)

    Botha, L R; Bollig, C; Esser, M J D; Campbell, R N; Jacobs, C; Preussler, D R


    A Ho:YLF laser pumped HBr molecular laser was developed that produced up to 2.5 mJ of energy in the 4 micron wavelength region. The Ho:YLF laser was fiber pumped using a commercial Tm:fibre laser. The Ho:YLF laser was operated in a single longitudinal mode via injection seeding with a narrow band diode laser which in turn was locked to one of the HBr transitions. The behavior of the HBr laser was described using a rate equation mathematical model and this was solved numerically. Good agreement both qualitatively and quantitatively between the model and experimental results was obtained.

  6. HoME: a Household Multimodal Environment


    Brodeur, Simon; Perez, Ethan; Anand, Ankesh; Golemo, Florian; Celotti, Luca; Strub, Florian; Rouat, Jean; Larochelle, Hugo; Courville, Aaron


    We introduce HoME: a Household Multimodal Environment for artificial agents to learn from vision, audio, semantics, physics, and interaction with objects and other agents, all within a realistic context. HoME integrates over 45,000 diverse 3D house layouts based on the SUNCG dataset, a scale which may facilitate learning, generalization, and transfer. HoME is an open-source, OpenAI Gym-compatible platform extensible to tasks in reinforcement learning, language grounding, sound-based navigatio...

  7. Sites of Lu(III) sorbed to and coprecipitated with hectorite. (United States)

    Finck, Nicolas; Schlegel, Michel L; Bosbach, Dirk


    The Lu(III) binding mechanisms by trioctahedral smectite hectorite in aqueous systems were investigated by extended X-ray absorption fine structure (EXAFS) spectroscopy. Coprecipitated hectorite (Lu755Hec), its precursor phase (Lu/Brucite), and the surface sorbed hectorite (Lu/SHCa1) were prepared as oriented samples to collect polarized EXAFS (P-EXAFS) data. EXAFS analysis indicated that Lu(III) is 6-fold coordinated by oxygen in Lu/Brucite and in Lu755Hec, and surrounded by Mg/Si shells. The angular dependence of the O and Mg coordination numbers for Lu/Brucite hinted an Lu(III) incorporation in brucite layers. Mg and Si cationic shells were detected at distances suggesting a clay-like octahedral environment in Lu755Hec. EXAFS data for Lu/SHCa1 were consistent with Lu(III) forming inner-sphere surface complexes at hectorite platelets edges, but slightly above/below the octahedral plane. Finally, Lu(III) polyhedra share edge(s) and corner(s) with Si tetrahedra upon sorption to silica (Lu/Silica). Lu(III) binding to silicate oligomers or to silicate groups of the clay basal planes and formation of Lu(III) surface complexes during the coprecipitation experiment are marginal.

  8. Reaction rate constant of HO2+O3 measured by detecting HO2 from photofragment fluorescence (United States)

    Manzanares, E. R.; Suto, Masako; Lee, Long C.; Coffey, Dewitt, Jr.


    A room-temperature discharge-flow system investigation of the rate constant for the reaction 'HO2 + O3 yields OH + 2O2' has detected HO2 through the OH(A-X) fluorescence produced by photodissociative excitation of HO2 at 147 nm. A reaction rate constant of 1.9 + or - 0.3 x 10 to the -15th cu cm/molecule per sec is obtained from first-order decay of HO2 in excess O3; this agrees well with published data.

  9. Laulupidu, kultuurimälu ja rahvuslik identiteet / Marge Allandi

    Index Scriptorium Estoniae

    Allandi, Marge


    Artikkel on koostatud Marge Allandi magistritöö "Laulupidu kui rituaal: Eesti üldlaulupeod rahvusliku kultuurimälu ja identiteedi kujundajate ja kandjatena" põhjal, mis kaitsti Tallinna Ülikooli Eesti Humanitaarinstituudis 2009. aastal

  10. Jeg Er blevet FRANKofil

    DEFF Research Database (Denmark)

    Andersson, Lasse


    afhængig af Frank Underwood fra serien House of Cards på den fremadstormende TV-streamingstjenesten Netflix. Jeg har opdaget et nyt internetbaseret datingforhold. Et surrealt, fedt miks af det kyniske og joviale personificeret i karakteren Frank Underwood, som er helt igennem ubehagelig, men fantastisk...... spillet af Kevin Spacey. Og tak til Spacey der for en tid har forladt teateret ’The Old Vic’ i London for at begejstre mig. Der er generelt to årsager til mine FRANKofile tilbøjeligheder. For det første er Netflix’s remake af den tyve år gamle BBC serie House of Cards efter min menig et stykke tv...... anden grund, til at jeg er blevet Frankofil, er, at jeg ikke skal sidde og vente på næste søndag efter søndag efter søndag for at få lov at se næste afsnit. Netflix lagde alle tretten timer af sæson 2 ud på nettet. Jeg afgør selv, hvornår jeg skal have mere Frank! Men på trods af mit narkomanlignende...

  11. Innovation er brugerdreven!

    DEFF Research Database (Denmark)

    Helms, Niels Henrik


    Brugerdreven innovation er blevet svaret på mange af de udfordringer, som vores moderne samfund står overfor.Det er skrevet ind i såvel regeringsgrundlaget som i de forskellige tiltag, som skal ruste Danmark i forhold til globaliseringen. Vi har ifølge argumentationen her enrække særlige forudsæt......Brugerdreven innovation er blevet svaret på mange af de udfordringer, som vores moderne samfund står overfor.Det er skrevet ind i såvel regeringsgrundlaget som i de forskellige tiltag, som skal ruste Danmark i forhold til globaliseringen. Vi har ifølge argumentationen her enrække særlige...... forudsætninger: samspillet mellem virksomhederne, samspillet mellem forskning, virksomheder og fx erhvervspolitiske tiltag, den særlige danske designtradition. Samtidig er det netop innovationen og især den brugerdrevne innovation, som giver og isærdeleshed skal give Danmark en rolle i en globaliseret økonomi...

  12. Deuteron induced reactions on Ho and La: Experimental excitation functions and comparison with code results

    Energy Technology Data Exchange (ETDEWEB)

    Hermanne, A., E-mail: [Cyclotron Laboratory, Vrije Universiteit Brussel, Brussel 1090 (Belgium); Adam-Rebeles, R. [Cyclotron Laboratory, Vrije Universiteit Brussel, Brussel 1090 (Belgium); Tarkanyi, F.; Takacs, S.; Csikai, J. [Institute for Nuclear Research, Hungarian Academy of Sciences, 4026 Debrecen (Hungary); Takacs, M.P. [Institute of Physics, University of Debrecen, 4026 Debrecen (Hungary); Ignatyuk, A. [Institute of Physics and Power Engineering, Obninsk 246020 (Russian Federation)


    Activation products of rare earth elements are gaining importance in medical and technical applications. In stacked foil irradiations, followed by high resolution gamma spectroscopy, the cross-sections for production of {sup 161,165}Er, {sup 166g}Ho on {sup 165}Ho and {sup 135,137m,137g,139}Ce, {sup 140}La, {sup 133m,133g,cum}Ba and {sup 136}Cs on {sup nat}La targets were measured up to 50 MeV. Reduced uncertainty is obtained by simultaneous remeasurement of the {sup 27}Al(d,x){sup 24,22}Na monitor reactions over the whole energy range. A comparison with experimental literature values and results from updated theoretical codes (ALICE-D, EMPIRE-D and the TENDL2012 online library) is discussed.

  13. HO-CHUNK: Radiation Transfer code (United States)

    Whitney, Barbara A.; Wood, Kenneth; Bjorkman, J. E.; Cohen, Martin; Wolff, Michael J.


    HO-CHUNK calculates radiative equilibrium temperature solution, thermal and PAH/vsg emission, scattering and polarization in protostellar geometries. It is useful for computing spectral energy distributions (SEDs), polarization spectra, and images.

  14. The neuroprotective effect of heme oxygenase (HO) on oxidative stress in HO-1 siRNA-transfected HT22 cells. (United States)

    Kaizaki, Asuka; Tanaka, Sachiko; Ishige, Kumiko; Numazawa, Satoshi; Yoshida, Takemi


    To investigate the role of heme oxygenase (HO) isozymes, we used siRNA technology to suppress HO-1 expression. HO-1 siRNA-transfected HT22 cells were vulnerable to hydrogen peroxide- and 4-hydroxynonenal-induced cytotoxicity. Biliverdin and bilirubin, degradative products of heme catalyzed by HO, protected HT22 cells from the insult of these oxidative stressors. These results suggest that inducible HO-1 plays a protective role against oxidative stress in HT22 cells.

  15. Exploiting fine-grain parallelism in recursive LU factorization

    KAUST Repository

    Dongarra, Jack


    The LU factorization is an important numerical algorithm for solving system of linear equations. This paper proposes a novel approach for computing the LU factorization in parallel on multicore architectures. It improves the overall performance and also achieves the numerical quality of the standard LU factorization with partial pivoting. While the update of the trailing submatrix is computationally intensive and highly parallel, the inherently problematic portion of the LU factorization is the panel factorization due to its memory-bound characteristic and the atomicity of selecting the appropriate pivots. We remedy this in our new approach to LU factorization of (narrow and tall) panel submatrices. We use a parallel fine-grained recursive formulation of the factorization. It is based on conflict-free partitioning of the data and lock-less synchronization mechanisms. Our implementation lets the overall computation naturally flow with limited contention. Our recursive panel factorization provides the necessary performance increase for the inherently problematic portion of the LU factorization of square matrices. A large panel width results in larger Amdahl\\'s fraction as our experiments have revealed which is consistent with related efforts. The performance results of our implementation reveal superlinear speedup and far exceed what can be achieved with equivalent MKL and/or LAPACK routines. © 2012 The authors and IOS Press. All rights reserved.

  16. Pao-Lu Hsu (Xu, Bao-lu): The Grandparent of Probability and Statistics in China


    Chen, Dayue; Olkin, Ingram


    The years 1910–1911 are auspicious years in Chinese mathematics with the births of Pao-Lu Hsu, Luo-Keng Hua and Shiing-Shen Chern. These three began the development of modern mathematics in China: Hsu in probability and statistics, Hua in number theory, and Chern in differential geometry. We here review some facts about the life of P.-L. Hsu which have been uncovered recently, and then discuss some of his contributions. We have drawn heavily on three papers in the 1979 Annals of Statistics (v...

  17. Tale er guld

    DEFF Research Database (Denmark)

    Juel Henrichsen, Peter


    Mange danske kommuner er parate til at indfase automatisk talegenkendelse, men er samtidig nervøse efter en lang række dårlige businesscases i den nærmere fortid. Der klages over høje licenspriser og lavt serviceniveau, den typiske virkning af et de facto monopol på leverandørsiden. Denne artikel...... området - som vi håber at se i 2014 - en begivenhed som præcis kunne løsne den nuværende deadlock og åbne et milliardstort marked for taleteknologi i det offentliges tjeneste....

  18. Bioenergi er blevet moderne

    DEFF Research Database (Denmark)

    Sønderberg Petersen, L.


    Risø har udgivet en rapport om moderne bioenergi. Den slår fast, at biomasse er en ligeså værdifuld ressource som vind, og at Danmark vil kunne spille en væsentlig rolle i udviklingen af den teknologi, der skal til for at udnytte hele dens potentiale.......Risø har udgivet en rapport om moderne bioenergi. Den slår fast, at biomasse er en ligeså værdifuld ressource som vind, og at Danmark vil kunne spille en væsentlig rolle i udviklingen af den teknologi, der skal til for at udnytte hele dens potentiale....

  19. Ondskaben er fortryllende

    DEFF Research Database (Denmark)

    Schubart, Rikke


    Indlæg om tv-serien Once Upon a Time (2011-), der hører til genren fairytale fantasy, der blander eventyr og fantasy. Her bliver alle eventyr brugt i en fortælling om alle beboere i en lille by, der ikke ved, at de i virkeligheden er eventyr-karakterer....

  20. Riget - alt er tilladt

    DEFF Research Database (Denmark)

    Agger, Gunhild


    Riget indtager en nøglestilling, når overgangen mellem faser i Triers produktion skal karakteriseres. Riget danner bro mellem den billedfascination og de radikale stileksperimenter, der præger Triers tidlige produktion, og den genre- og plotbevidsthed, der er typisk for film som Breaking the Wave...... (1996) og Dancer in the Dark (2000). Artiklen analyserer hvordan....

  1. It er godt - basta!

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe


    Der er offentlig konsensus om at it i undervisningen fører til øget faglighed. Men it kan lige så godt resultere i ringere undervisning som i bedre - og ofte anvendes it helt traditionelt og fantasiløst....

  2. Hvad er tidligt sprog

    DEFF Research Database (Denmark)

    Skriver Jensen, Anders


    Forfatteren argumenterer for at "early literacy" kan oversættes til "tidligt sprog"; særligt når der er tale om en helhedsorienteret tilgang med vægt på sprog som et alsidigt medie for kommunikation- og betydningsskabelse. Med inspiration fra Jerome Bruners kulturpsykologi diskuteres mulige...

  3. Litteratur er nyttig

    DEFF Research Database (Denmark)

    Kaspersen, Peter


    Den anmeldte bog er en forskningsbaseret debatbog om hvilken nytteværdi litteratur har. Bogen placeres i sammenhæng med en række bøger på nordiske sprog og engelsk om litteraturens, litteraturundervisningens og -forskningens legitimitet. Argumentatioen i bogen bygger på Bakhtins litteratursyn, og...

  4. Ideologi er noget bras

    DEFF Research Database (Denmark)

    Hansen, Brian Benjamin; Jøker Bjerre, Henrik

    fra den slovenske filosof Slavoj Zizek stilles imidlertid det spørgsmål i bogen, om ideologien idag ikke blot har taget en anden form. Vi lever i dag ikke i post-ideologiske tider. Snarere er braset selv – X Factor, forbrugsobjekter, underholdning, følelser og balloner – blevet den næsten usynlige...

  5. er 1999

    DEFF Research Database (Denmark)

    Jensen, J. P.; Søndergaard, M.; Jeppesen, E.

    land bidrager med flest næringsstoffer til søerne Stoftilførslen af såvel fosfor som kvælstof til søerne har i 1999 som tidligere år været domineret af tilførslen fra det åbne land, der gen-nemsnitligt har bidraget med ca. 73 % af fosfortilførslen og ca. 78 % af kvælstoftilførslen (Fig. 0...... for de mest belastede søer. Således er både fosfor- og kvælstof-bidraget fra byspildevand og industrispildevand fra 1989 til 1999 reduceret meget markant fra ca. 22 % til ca. 3 %. Figur 0.1 Kildefordeling for fosfor- og kvælsstoftilførslen til søerne i 1999. Grå: Åbent land (landbrug + baggrund). Sort...... af overvågningssøerne, efter at søer-ne er blevet klarvandede som følge af ændringer i fiskebestanden. I halvdelen af søerne var kvælstof-tilbageholdelsen i 1999 højere end 26 %. Medianen og gennemsnittet for den absolutte kvælstoftilbagehol-delse var 93 og 111 mg N m-2 dag-1 svarende til 340 og 405...

  6. Hvad er alternativet?

    DEFF Research Database (Denmark)

    Jensen, Niels Rosendal


    Anmeldelsen af Mårtenssons "Konkurrencestatens pædagogik" præsenterer dels forfatterens kritik af og alternativ til den igangværende reform af folkeskolen, dels advarer den mod at forfalde til konspirationsteori. Endelig peger den på, at Mårtenssons såkaldte alternativ er gammel vin på nye flaske...

  7. Patienten - hvor er patienten?

    DEFF Research Database (Denmark)

    Nielsen, Gitte; Dau, Susanne


    på, hvad der historisk og nutidigt karakteriserer teori og praksis, samt forholdet herimellem. I den empiriske del er der, med udgangspunkt i Gadamers hermeneutiske tilgang, foretaget tre kvalitative forkusgruppeinterview. Ét af sygeplejestuderende, ét af kliniske vejledere og ét af undervisere...

  8. Er danskerne racister?

    DEFF Research Database (Denmark)

    Necef, Mehmet Ümit; Bech, Henning

    Igennem de seneste årtier er det blevet almindeligt at tale om, at der er en udbredt racisme i Danmark. Påstande om danskernes racisme, fremmedhad og diskrimination optræder dagligt i offentligheden og i medierne, og der henvises ofte til, hvad ’forskerne’ og de ’videnskabelige undersøgelser’ siger...... om emnet. Der kan da næppe heller være tvivl om, at der forekommer racistiske holdninger hos nogle danskere. Men er problemet så stort, som det gøres til i den offentlige debat? Bogen ønsker at afklare, hvorvidt der er videnskabelig dokumentation for påstandene om danskernes racisme. Den går i dybden...... med en række forskeres og eksperters udtalelser på området og præsenterer en grundig analyse af deres fremstilling af dansk racisme i forhold til emner som kultur, seksualitet, kriminalitet og arbejdsmarked....

  9. Nordslesvigeren er nr. 1

    DEFF Research Database (Denmark)

    Christensen, Steffen Lind


    Historien om de nordslesvigske krigsdeltagere under 1. Verdenskrig er traditionelt blevet behandlet i et nationalt perspektiv. Her benævnes soldaterne oftest som ’danske’. Denne artikel undersøger, hvordan nordslesvigske soldater på Østfronten selv udtrykte deres identitet i krigssituationen...

  10. Beam delivery system for Ho:YLF and applications in endodontics; Sistema de entrega de feixe para laser de Ho:YLF e aplicacoes em endodontia

    Energy Technology Data Exchange (ETDEWEB)

    Bachmann, Luciano


    The beam delivery systems, whether using fibers or articulated arms, are very important for the expansion of laser applications into life sciences. This work aims to couple an optical fiber to a home-made Er:Tm:Ho:LiYF{sub 4} laser. For this purpose the beam profile was studied using the beam quality factor M{sup 2} to achieve an homogeneous beam. To determine the M{sup 2} factor, the knife-edge technique was used, relating the laser energy eclipsed by the knife with its transversal position. The resonant cavity was made suitable in order to obtain a stable and homogeneous transversal beam profile, for the optical fiber coupling. It was used a 365 {mu}m diameter core low OH{sup -} content fused silica optical fiber, with a proximal SMA-905 connection and a flat distal end. M{sup 2} factors for the Ho:YLF were between 3 and 8, with a non astigmatic beam, although it was observed a divergence asymmetry in the transversal sections. The coupling efficiency was 96%, and in a repeated operation without any adjustment, the new coupling were 82% and 81%. Lasers have being recently used as an adjunct to conventional endodontic preparation to reduce intracanal microbial, preventing reinfection. The knowledge of thermal profile in endodontic procedures is important to determine laser irradiation conditions avoiding periodontal damages. In this sense, the second scope of this work was to use the Ho:YLF system to register the thermal profile in vitro and to compare the results with those obtained with Nd:YAG and Er:YAG commercial lasers. The temperature was recorded in real time through a thermocouple probe at the root apex , resulting in maximum increase of 7 deg C. (author)

  11. The role of HO_x in super- and subsonic aircraft exhaust plumes


    Hanisco, T. F.; Wennberg, P. O.; R. C. Cohen; J. G. Anderson; D. W. Fahey; Keim, E. R; Gao, R. S.; Wamsley, R. C.; Donnelly, S. G.; Del Negro, L. A.; R. J. Salawitch; Kelly, K. K.; Proffitt, M.H.


    The generation of sulfuric acid aerosols in aircraft exhaust has emerged as a critical issue in determining the impact of supersonic aircraft on stratospheric ozone. It has long been held that the first step in the mechanism of aerosol formation is the oxidation of SO_(2) emitted from the engine by OH in the exhaust plume. We report in situ measurements of OH and HO_(2) in the exhaust plumes of a supersonic (Air France Concorde) and a subsonic (NASA ER-2) aircraft in the lower stratosphere. T...

  12. High energy gamma rays in the decay of 27h Ho166

    DEFF Research Database (Denmark)

    Hansen, P.Gregers; Wilsky, K.; Horen, D.J.


    The gamma-ray spectrum of 27th Ho166 was re-investigated by means of a three-crystal pair-spectrometer and coincidence techniques. Two new gamma rays with energies of 1747 plusmn 5 and 1825 plusmn 5 keV establish a new level at 1826 keV in Er166. The log ft value for the beta-decay to this state...... is 5.2-0,4+0.3 and suggests an allowed unhindered transition. Single particle assignments for this level are discussed....

  13. Adhesive activity of Lu glycoproteins is regulated by interaction with spectrin

    Energy Technology Data Exchange (ETDEWEB)

    An, Xiuli; Gauthier, Emilie; Zhang, Xihui; Guo, Xinhua; Anstee, David; Mohandas, Narla; Anne Chasis, Joel


    The Lutheran (Lu) and Lu(v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu(v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated. In the present study, we defined the binding motifs of Lu and Lu(v13) on spectrin and identified a functional role for this interaction. We found that the cytoplasmic domains of both Lu and Lu(v13) bound to repeat 4 of the spectrin chain. The interaction of full-length spectrin dimer to Lu and Lu(v13) was inhibited by repeat 4 of {alpha}-spectrin. Further, resealing of this repeat peptide into erythrocytes led to weakened Lu-cytoskeleton interaction as demonstrated by increased detergent extractability of Lu. Importantly, disruption of the Lu-spectrin linkage was accompanied by enhanced cell adhesion to laminin. We conclude that the interaction of the Lu cytoplasmic tail with the cytoskeleton regulates its adhesive receptor function.

  14. Projektový manažer jako manažer projektového týmu


    Markvart, Ondřej


    The thesis topic is linking of knowledge from psychology and psychodiagnosis within project management. The thesis has several aims, which are all introduced in the first chapter. One of those aims is the introduction of contemporary ways, methods and standards used in project management. Another aim is equipping a project manager with knowledge from psychology and psychodiagnosis, which still constitute a comparatively neglected area of project management. What their utilization can actually...

  15. LU-HF Age and Isotope Systematics of ALH84001 (United States)

    Righter, M.; Lapen, T. J.; Brandon, A. D.; Beard, B. L.; Shafer, J. T.; Peslier, A. H.


    Allan Hills (ALH) 84001 is an orthopyroxenite that is unique among the Martian meteorites in having the oldest inferred crystallization age (approx..4.5 to 4.0 Gyr) [e.g., 1-6 and references therein 7]. Its ancient origin makes this stone a critical constraint on early history of Mars, in particular the evolution of different planetary crust and mantle reservoirs. However, because there is significant variability in reported crystallization ages, determination of initial isotope compositions is imprecise making assessment of planetary reservoirs difficult. Here we report a new Lu-Hf mineral isochron age, initial Hf-176/Hf-177 isotope composition, and inferred Martian mantle source compositions for ALH84001 that place constraints on longlived source reservoirs for the enriched shergottite suite of Martian meteorites including Shergotty, Zagami, NWA4468, NWA856, RBT04262, LAR06319, and Los Angeles. Sm-Nd isotope analyses are under way for the same mineral aliquots analyzed for Lu-Hf. The Lu-Hf system was utilized because Lu and Hf are both lithophile and refractory and are not easily redistributed during short-lived thermal pulses associated with shock metamorphism. Moreover, chromite has relatively modest Hf concentrations with very low Lu/Hf ratios [9] yielding tight constraints on initial Hf-176/Hf-177 isotope compositions

  16. Er HR ude i tovene?

    DEFF Research Database (Denmark)

    Poulfelt, Flemming


    HR: Er der behov for nytænkning i HR-land? Artikler i Harvard Business Review - bakket op af en dansk undersøgelse - konkluderer, at HR stadig mangler gennemslagskraft i virksomhederne. Er HR ude i tovene? ... For i undersøgelsen "Ny Dansk Ledelse" (maj 2015), som er baseret på danske lederes...

  17. LU 302 872 and its racemate (LU 224 332) show balanced endothelin-A/B receptor affinity, high oral activity, and inhibit human prostate tissue contractions. (United States)

    Raschack, M; Göck, S; Unger, L; Hahn, A; Amberg, W; Jansen, R; Alken, P; Weber, A; Hergenröder, S


    LU 302 872 (racemate LU 224 332) is a new glycerinic acid derivative related to the selective ETA receptor antagonist LU 135 252. LU 302 872 exhibits high and balanced affinity to ETA and ETB receptors (Ki 2.2 and 5.8 nmol/L), whereas LU 135 252 is ETA-selective (Ki 1.4 and 184 nmol/L). Two hours after oral treatment of rats with 10 mg/kg of LU 302 872 or of LU 135 252, the big ET-1-induced (20 micrograms/kg i.v.) blood pressure increase is inhibited by 59 +/- 8% or 52 +/- 2% (n = 6-8; p testing in benign prostate hyperplasia (BPH).

  18. Facebook er internettet nu

    DEFF Research Database (Denmark)

    Tække, Jesper


    Den store vision for world wide web var, at alle kunne få ubegrænset adgang til alverdens information. www var mangfoldigt og anarkistisk. I dag er der rigtig mange, der kun bruger nettet til at være på Facebook. Hvad bruger Facebook det til? Og hvad gør det ved vores udsyn?......Den store vision for world wide web var, at alle kunne få ubegrænset adgang til alverdens information. www var mangfoldigt og anarkistisk. I dag er der rigtig mange, der kun bruger nettet til at være på Facebook. Hvad bruger Facebook det til? Og hvad gør det ved vores udsyn?...

  19. Hvad er en by?

    DEFF Research Database (Denmark)

    Parby, Jakob; Thelle, Mikkel


    Nytænkning. Med de moderne megabyer er det slut med at forestille sig byen som noget, man planlægger og giver form. Vi skal lære at se dem som vildtvoksende urbane landskaber. Artikel om megabyer, byudvikling og forestillingen om byen gennem tiderne. Skrevet delvist i anledning af åbningen af...... udstillingen Citambulos på Københavns Museum, der handlede om Mexico City....

  20. Hvis er Himmeriget?

    DEFF Research Database (Denmark)

    Holst, Søren


    Udtrykket "de fattige i ånden", som kendes fra Bjergprædikenen i Matthæusevangeliet, forekommer også i to af Dødehavsrullerne. Artiklen undersøger disse tekster og argumenterer for, at udtrykket ikke betegner en særligt "åndelig" fattigdom, men derimod de konkret økonomisk fattige, som er "af ånd...

  1. er 2000

    DEFF Research Database (Denmark)

    Jensen, J. P.; Søndergaard, M.; Jeppesen, E.

    ændringer i be-lastningen af vand-miljøet med nærings-salte. Med NOVA er programmet udvidet til at omfatte både vand-miljøets tilstand i bredeste forstand og miljøfremmede stoffer og tungmetaller. Danmarks Miljøundersø-gelser har som sektor-forskningsinstitu-tion i Miljøministeriet til opgave at forbedre og...

  2. Han er her endnu

    DEFF Research Database (Denmark)

    Bonde, Lisbeth


    Interview med den kinesiske aktivist og billedkunstner Ai Weiwei, der sad fængslet i 81 dage i 2011. Hans pas er stadig (i februar 2014) inddraget af myndighederne, så han kan ikke forlade landet, selv om han har betalt en bøde på 13 mio. kr. for ”skatteunddragelse”. Både i sin kunst og i sine ma...

  3. Conversion of homothallic yeast to heterothallism trough HO gene disruption

    CSIR Research Space (South Africa)

    Van Zyl, WH


    Full Text Available A simple method was developed for the conversion of homothallic Saccharomyces cerevisiae yeaststrains to heterothallism through HO gene disruption. An integrative ho:: neo disrupted allele was constructed by cloning a dominant selectable marker...

  4. Eutanázie z pohledu ošetřovatelského personálu


    LENKOVÁ, Gabriela


    The title of the thesis is Euthanasia from the Point of View of Nursing Staff. The work is divided into the theoretical and practical part.The objective of the thesis is to map nursing staff?s views of euthanasia. I set two research questions. 1. Do the nurses at selected wards tend to the opinion that euthanasia should or should not be legalized? 2. What circumstances lead to their opinion? I applied qualitative research, the method of questioning and the technique of a semi-structured inter...

  5. Příprava výukového materiálu pro tvorbu GUI v MATLABu


    ŠIMEK, Jakub


    The aim of this thesis is to create an educational material for creating graphical user interfaces in MATLAB. The reader will learn the basic procedures of the GUI creation, get to know the various graphic objects and learn about the GUIDE environment, which is intended for the actual application development. Text is supplemented by practical examples of source code fragments as much as possible. All material is accompanied by two functional sample applications with their source code.

  6. Návrh webového portálu pro rozvoj dark tourismu v JMK


    Vágnerová, Yvonne


    Concept of the web portal for development of the dark tourism in JMK. Bachelor thesis. Brno: MENDELU in Brno, 2016. This bachelor thesis is focusing on creating a concept of the web portal for development of the so called dark tourism in JMK. It researches current state of the dark tourism market and proposes suitable marketing mix for consequent propagation of the aforementioned web portal. Last part of thesis describes the actual concept and design of the microsite.

  7. Lifetimes in {sup 161}Lu measured with recoil distance method

    Energy Technology Data Exchange (ETDEWEB)

    Yu, C.H.; Lewis, J.M.; Riedinger, L.L. [and others


    High spin states of {sup 161}Lu are populated using the {sup 120}Sn({sup 45}Sc,4n){sup 161}Lu reaction with a 205 MeV {sup 45}Sc beam provided by the Oak Ridge National Lab. A plunger was used to stop the recoils at various distances and the {gamma}-rays were detected by the compact array of 20 Compton-suppressed Ge detectors of 17, 30, 60, 85, 140, 210, and 320 micrometers. These data are being analyzed in order to extract lifetimes. High spin lifetimes in the {pi}h{sub 11/12}, 9/2[514] band of {sup 161}Lu were previously measured with DSAM technique. Large energy signature splitting was observed in the low spin portion of this band, which has been interpreted as the evidence for triaxiality and small quadrupole deformation. The authors measured lifetimes at low spin will be helpful for the verification of this prediction.

  8. An overview of SuperLU: Algorithms, implementation, and userinterface

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoye S.


    We give an overview of the algorithms, design philosophy,and implementation techniques in the software SuperLU, for solving sparseunsymmetric linear systems. In particular, we highlight the differencesbetween the sequential SuperLU (including its multithreaded extension)and parallel SuperLU_DIST. These include the numerical pivoting strategy,the ordering strategy for preserving sparsity, the ordering in which theupdating tasks are performed, the numerical kernel, and theparallelization strategy. Because of the scalability concern, theparallel code is drastically different from the sequential one. Wedescribe the user interfaces ofthe libraries, and illustrate how to usethe libraries most efficiently depending on some matrix characteristics.Finally, we give some examples of how the solver has been used inlarge-scale scientific applications, and the performance.

  9. Spin Waves in Ho2Co17

    DEFF Research Database (Denmark)

    Clausen, Kurt Nørgaard; Lebech, Bente


    Spin wave excitations in a single crystal of Ho2Co17 have been studied at 4.8 and 78 K. The results are discussed in terms of a linear spin wave model. At 78 K both ground state and excited state spin waves are observed.......Spin wave excitations in a single crystal of Ho2Co17 have been studied at 4.8 and 78 K. The results are discussed in terms of a linear spin wave model. At 78 K both ground state and excited state spin waves are observed....

  10. Ternary silicides ScIr{sub 4}Si{sub 2} and RERh{sub 4}Si{sub 2} (RE = Sc, Y, Tb-Lu) and quaternary derivatives RERh{sub 4}Si{sub 2-x}Sn{sub x} (RE = Y, Nd, Sm, Gd-Lu) - structure, chemical bonding, and solid state NMR spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Vosswinkel, Daniel; Benndorf, Christopher; Poettgen, Rainer [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Eckert, Hellmut [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Sao Paulo Univ., Sao Carlos (Brazil). Inst. of Physics; Matar, Samir F. [Bordeaux Univ., CNRS, ICMCB, UPR 9048, Pessac (France)


    The silicides ScIr{sub 4}Si{sub 2} and RERh{sub 4}Si{sub 2} (RE = Sc, Y, Tb-Lu) and silicide stannides RERh{sub 4}Si{sub 2-x}Sn{sub x}(RE = Y, Nd, Sm, Gd-Lu) were synthesized from the elements by arc-melting and subsequent annealing. The new compounds crystallize with the orthorhombic YRh{sub 4}Ge{sub 2} type structure, space group Pnma. They were characterized by X-ray powder patterns and several structures were refined from single crystal X-ray diffractometer data. The main structural motifs of this series of silicides are tricapped trigonal prisms formed by the transition metal and rare earth atoms. One of the two crystallographically independent silicon sites allows for formation of solid solutions with tin, exemplarily studied for ErRh{sub 4}Si{sub 2-x}Sn{sub x}. Electronic structure calculations reveal strong covalent Rh-Si bonding as the main stability factor. Multinuclear ({sup 29}Si, {sup 45}Sc, and {sup 89}Y) magic-angle spinning (MAS) NMR spectra of the structure representatives with diamagnetic rare-earth elements (Sc, Y, Lu) are found to be consistent with the crystallographic data and specifically confirm the selective substitution of Sn in the Si2 sites in the quaternary compounds YRh{sub 4}SiSn and LuRh{sub 4}SiSn.

  11. Revisiting the Level Scheme of the Proton Emitter 151Lu (United States)

    Wang, F.; Sun, B. H.; Liu, Z.; Scholey, C.; Ashley, S. F.; Bianco, L.; Cullen, D. M.; Cullen, I. J.; Darby, I. G.; Eeckhaudt, S.; Garnsworthy, A. B.; Gelletly, W.; Gomez-Hornillos, M. B.; Grahn, T.; Greenlees, P. T.; Jenkins, D. G.; Jones, G. A.; Jones, P.; Joss, D. T.; Julin, R.; Juutinen, S.; Kettelhut, S.; Khan, S.; Kishada, A.; Leino, M.; Niikura, M.; Nyman, M.; Page, R. D.; Pakarinen, J.; Pietri, S.; Podolyak, Z.; Rahkila, P.; Rigby, S.; Saren, J.; Seweryniak, D.; Shizuma, T.; Simpson, J.; Sorri, J.; Steer, S.; Thompson, N. J.; Uusitalo, J.; Walker, P. M.; Williams, S.

    An experiment aiming to search for new isomers in the region of proton emitter 151Lu was performed at the Accelerator Laboratory of the University of Jyväskylä (JYFL), by combining the high resolution γ-ray array JUROGAM, gas-filled RITU separator and GREAT detectors with the triggerless total data readout acquisition (TDR) system. In this proceeding, we revisit the level scheme of 151Lu by using the proton-tagging technique. A level scheme consistent with the latest experimental results is obtained, and 3 additional levels are identified at high excitation energies.

  12. Naltrexone ER/Bupropion ER: A Review in Obesity Management. (United States)

    Greig, Sarah L; Keating, Gillian M


    Oral naltrexone extended-release/bupropion extended-release (naltrexone ER/bupropion ER; Contrave(®), Mysimba(™)) is available as an adjunct to a reduced-calorie diet and increased physical activity in adults with an initial body mass index (BMI) of ≥ 30 kg/m(2) (i.e. obese) or a BMI of ≥ 27 kg/m(2) (i.e. overweight) in the presence of at least one bodyweight-related comorbidity, such as type 2 diabetes mellitus, hypertension or dyslipidaemia. In 56-week phase III trials in these patient populations, oral naltrexone ER/bupropion ER 32/360 mg/day was significantly more effective than placebo with regard to percentage bodyweight reductions from baseline and the proportion of patients who achieved bodyweight reductions of ≥ 5 and ≥ 10%. Significantly greater improvements in several cardiometabolic risk factors were also observed with naltrexone ER/bupropion ER versus placebo, as well as greater improvements in glycated haemoglobin levels in obese or overweight adults with type 2 diabetes. Naltrexone ER/bupropion ER was generally well tolerated in phase III trials, with nausea being the most common adverse event. Thus, naltrexone ER/bupropion ER 32/360 mg/day as an adjunct to a reduced-calorie diet and increased physical activity, is an effective and well tolerated option for chronic bodyweight management in obese adults or overweight adults with at least one bodyweight-related comorbidity.

  13. Fabrication and characterization of spark plasma sintered Ce:LuAG ceramic for scintillation application

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S. Arun; Senthilselvan, J., E-mail: [Department of Nuclear Physics, University of Madras, Guindy Campus, Chennai–600 025, Tamil Nadu (India)


    Rare earth Cerium doped Lutetium Aluminum Garnet (Ce:LuAG) ceramics are widely used as phosphor material in medical imaging and high-energy physics. Due to its technological importance, an attempt has been made to fabricate Ce:LuAG ceramics by using spark plasma sintering (SPS) technique. XRD patterns of SPS sintered Ce:LuAG ceramics reveals a mixed LuAG and CeO{sub 2} (antisite defect) phases. The microstructures of SPS sintered Ce:LuAG ceramics shows limited densification, inappropriate compaction of particles and existence of residual pores, voids between the grain boundaries affects the transparency of Ce:LuAG ceramics. Relative density and hardness of post sintered Ce:LuAG ceramic is also determined. The effect of Ce{sup 3+} doping concentration and sintering temperature on optical luminescence behavior of Ce:LuAG ceramic is presented.

  14. Design popelářského vozu


    Běhal, Tomáš


    Tato diplomová práce se zabývá návrhem popelářského vozu. Vlastní návrh respektuje konstrukční požadavky vozu, ergonomické potřeby obsluhy a estetické nároky na moderní vozidlo určené pro sběr a odvoz odpadu. Návrh vychází ze znalostí získaných v rešeršní části, analýzy historické, technické a designérské. Řešený design je rámcově zasazen do současnosti, respektuje tedy dnešní technologie a výrobní možnosti. This master‘s thesis pertains to the design of a garbage truck. The presented desi...

  15. Ultraviolet Absorption Cross Sections of HO2NO2 Vapor. (United States)


    Pernitric acid (also called peroxynitric acid ), HO2 NO2 , is formed in the atmosphere by recombination of HO2 and NO2 radi- cals: HO2 + NO 2 M-- HO2 N02 (1...Jesson, J.P., L.P. Glasgow, D.L. Filkin, and C. Miller (1977), The Stratospheric Abundance of Peroxynitric Acid , Geophys. Res. Lett., 4, 513-516...and J.H. Shaw (1977), The Kinetics and Mechanism of the HO -NO Reactions: The Significance of Peroxynitric Acid Formation in Plotochemical Smog

  16. ASASSN-15lu is a Type Ia Supernova

    NARCIS (Netherlands)

    Leonard, D.C.; Sheehan, P.; McCarthy, D.; Follette, K.; Moustakas, J.; Cantillo, D.; Cazares-Kelly, A.; Cazares-Kelly, S.; Cendes, Y.; Damm, N.; Donati, A.; Douglas, E.; Ferrell, L.; Fosbinder-Elkins, H.; Fox, C.; Greenberg, M.; Hart, K.; Hensley, H.; Holt, A.; Hooper, E.; Juran, C.; Keane, J.; Key, K.; Korus, L.; Lee, T.; Leidig, K.; Merchak, E.; Nessmann, K.; Pendyala, S.; Pirkl, S.; Reeder, J.; Roos, A.; Rounseville, S.; Ruddy, E.; Schlingman, A.; Schlingman, W.; Schwartzman, E.; Shanmugam, V.; Silver, E.; Stein, A.; Stock, N.; Svoboda, B.; Thomas, B.; Thomas, N.; Thompson-Taylor, K.; Walton, H.


    We report spectroscopic classification of ASASSN-15lu (ATel #7698) in SDSS J132112.88+401556.7 (z=0.035037, via NED) through inspection of an optical spectrum (range 370-680 nm, resolution 0.8 nm), obtained with the 2.3-m Bok telescope (+ Boller & Chivens spectrograph) at Kitt Peak on 2015 June 24.2

  17. On the Stark Broadening of Lu III Spectral Lines

    Indian Academy of Sciences (India)

    interest for stellar plasma, as well as for laboratory plasma diagnosis, analysis and modeling, and also for laser produced plasma. As an example of potential astrophys- ical interest in our results, it was shown that Lu III lines exist whose Stark widths dominate the Doppler widths in some atmospheric layers of A-type stars.

  18. Phase diagram with an enhanced spin-glass region of the mixed Ising-XY magnet LiHoxEr1-xF4

    DEFF Research Database (Denmark)

    Piatek, J. O.; Dalla Piazza, B.; Nikseresht, N.


    We present the experimental phase diagram of LiHoxEr1-xF4, a dilution series of dipolar-coupled model magnets. The phase diagram was determined using a combination of ac susceptibility and neutron scattering. Three unique phases in addition to the Ising ferromagnet LiHoF4 and the XY antiferromagnet...

  19. Fragmentation Dynamics of Endohedral Fullerene Ho3N@C80 Ionized with Intense and Short X-Ray FEL Pulses (United States)

    Murphy, Brendan; Xiong, Hui; Fang, Li; Osipov, Timur; Kukk, Edwin; Petrovic, Vladmir; Li, Heng; Sistrunk, Emily; Squibb, Richard; Feifel, Raimund; Ferguson, Kenneth; Krzywinski, Jacek; Sebastian, Sebastian; Guehr, Markus; Bostedt, Christoph; Bucksbaum, Philip; Berrah, Nora


    The photoionization and fragmentation dynamics of gas phase endohedral fullerenes Ho3N@C80 with intense femtosecond X-ray pulses from the Linac Coherent Light Source (LCLS) free electron laser (FEL) have been investigated. The central photon energy of the x-ray pulses was set at 1530 eV, targeting the absorption of the 3d electron on Ho. Multiphoton ionization led to the highest charge state observed on the parent molecule to be Ho3N@C805+ , suggesting a stable structure even with 5 charges on the parent molecule. We will present the different atomic and molecular fragments dynamics observed. This work is funded by the Department of Energy, Office of Science, Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences under grant N. DE-FG02-92ER14299.A002 and in part by National Science Foundation under Grant No. 1404109.

  20. Rouw mag er zijn

    Directory of Open Access Journals (Sweden)

    Marlieke Moors


    Full Text Available ABSTRACTGrieving is allowedGrief is a human experience. Every form of loss shapes you into the human being you are today. Contrary to what earlier, unproven grief models postulate, grief does not have an end point. That is, bereavement does not have to be completely processed, but it should be integrated into someone’s life. The outdated grief models were often interpreted and used in a normative way, which led to a normative standard model. This portraits the belief that every mourner would experience similar symptoms and would go through a fixed pattern of phases. However, the updated vision emphasizes the individual and unique process of coping with loss: norms concerning grief should be banned. By means of literature research, interviews with professionals and personal experiences, it became clear that finding an equilibrium between restoration-orientated and loss-orientated coping styles is most beneficial. An important aspect in finding this balance is meaningfulness. Furthermore, the ability to bear a loss and to adapt accordingly are important components. Lastly, attaching significance to a loss is a constructive way of integrating the loss into one’s life. The death of a loved one should therefore not be forgotten or tucked away. After all, grief is the price we pay for love. SAMENVATTINGRouw mag er zijnRouw is een menselijke ervaring en elk verlies vormt je als mens. Rouw heeft, in tegenstelling tot wat de verouderde, niet bewezen rouwmodellen beweren, geen eindpunt. Verlies hoeft namelijk niet verwerkt te worden, maar moet juist geïntegreerd worden in iemands leven. De verouderde rouwmodellen zijn vaak normatief opgevat en toegepast, waaruit een normatief standaardmodel is ontstaan. Daarbij werd gedacht dat elke rouwende dezelfde symptomen zou vertonen en het rouwproces volgens vaste fasen zou verlopen. Binnen de vernieuwde visie wordt er juist van uitgegaan dat elk individu een unieke manier van reageren op rouw heeft. Er zou

  1. Alt er ændret. Intet er afklaret

    DEFF Research Database (Denmark)

    Helmersen, Ole


    Brexit kan redefinere landets internationale rolle lige så meget som Suezkrisen. Men 15 måneder efter afstemningen er der stadig ingen svar.......Brexit kan redefinere landets internationale rolle lige så meget som Suezkrisen. Men 15 måneder efter afstemningen er der stadig ingen svar....

  2. Pseudo-spin band in the odd-odd nucleus sup 1 sup 7 sup 2 Lu

    CERN Document Server

    Venkova, T; Gast, W; Podsvirova, E O; Jäger, H M; Mihailescu, L; Bazzacco, D; Menegazzo, R; Lunardi, S; Alvarez, C R; Ur, C; Martínez, T; Angelis, G D; Axiotis, M; Napoli, D; Urban, W; Rzaca-Urban, T; Frauendorf, S


    High-spin states in the odd-odd nucleus sup 1 sup 7 sup 2 Lu have been populated in a sup 1 sup 7 sup 0 Er( sup 7 Li,5n) reaction and the emitted gamma-radiation was detected with the GASP array. Two sequences of a new identical band have been observed with the transition energies in the favoured and unfavoured sequences being identical within approx 3 keV at low spins and approx 1 keV at high spins over the whole observed spin range. An interpretation as a pseudo-spin singlet band of pi 1/2 sup - [541] x nu 1/2 sup - [420] configuration is proposed. It represents the best example of a pseudo-spin singlet band in normal deformed nuclei known until now.

  3. Er talesprog en medieteknologi?

    DEFF Research Database (Denmark)

    Tække, Jesper


    for den menneskelige udfoldelse. Til at løse denne opgave vil jeg trække på den tyske sociolog og systemteoretiker Niklas Luhmann der også udmærker sig som medieteoretiker (Tække 2006a). Luhmann har ikke selv direkte redegjort for sprog som teknologi, men da han både har udviklet et brugbart...... motiver og viden, må give mening til hvad, der meddeles og selektere en forståelse (Luhmann 2000a). Formålet med og berettigelsen for medieteori er ud fra Marshall McLuhans (1967) devise, om at the medium is the message, at sammenligne, hvad det betyder for menneske og samfund, at der kommunikeres i ét...

  4. 10-W Ho laser for surgery (United States)

    Boutchenkov, Vyatcheslav A.; Utenkov, Boris I.; Antipenko, Boris M.; Berezin, Yuri D.; Malinin, Boris G.; Serebryakov, Victor A.


    Practical use of laser tecnique surgery demonstrated the true choice of lasers generating in the long wavelength spectrum. In this field the pigment content of biologic tissues is not noted at absorption spectrum. The latter is generally defined by the percentage of water in tissues. Among the known laser types the nost proved and developed are the lasers generating at 1060 nm, 2090 nm, 2900 nm and 10600 nm. Ho-lasers of 2090 nm radiation wavelength are perspective instruments for surgery purposes due to the high radiation absorption at biologic tissues: 30 cm-1. This value is much higher than the absoptance at 1060 nm and a little bit lower at 1060 nni. An important feature that distinguishes Ho-laser among other types is the possibility of its use with fiber channel made of fused silica for abdominal operations.

  5. Den rige personlighed er livsduelig

    DEFF Research Database (Denmark)

    Holm, Claus


    For omtrent 160 år siden formulerede Karl Marx forestillingen om en rig individualitet som det kommunistiske samfunds individideal. I dag får forestillingen relevans. Lyder det lidt besynderligt, er det ikke mærkeligt. For de fleste af os går næppe rundt og tror, at vi er lige på trapperne til...

  6. Kollegaerne er den nye chef

    DEFF Research Database (Denmark)

    Fugl, Marie


    Den tid, hvor chefen var den, der delte skideballer ud, er slut. Rollen som 'bad cop' er overtaget af kollegateamet, der med hård hånd sørger for, at den enkelte yder sin del. Udgivelsesdato: November...

  7. RNA er jo bare matematik!

    DEFF Research Database (Denmark)

    Blaavand, Jakob Lindblad


    Hvordan kan man kurere sygdomme med matematiske geometriske strukturer? Det kan man i princippet, hvis de geometriske figurer er RNA-molekyler, og sygdommen skyldes syge gener.......Hvordan kan man kurere sygdomme med matematiske geometriske strukturer? Det kan man i princippet, hvis de geometriske figurer er RNA-molekyler, og sygdommen skyldes syge gener....

  8. Fraflytning er ikke en naturlov

    DEFF Research Database (Denmark)

    Nørgaard, Helle


    DEBAT: Der er brug for en erkendelse af, at det ikke er en naturlov, at folk vil flytte til byerne. Forskning viser, at børnefamilier finder tryghed og ideelle rammer for familielivet på landet. Det skriver Helle Nørgaard, seniorforsker, ph.d., Statens Byggeforskningsinstitut, Aalborg Universitet....

  9. Er danske virksomheder mindre innovative?

    DEFF Research Database (Denmark)

    Madsen, Erik Strøjer; Smith, Valdemar; Nielsen, Anders Østergaard


    Med jævne mellemrum er det blevet fremhævet i de skrevne medier, at danske virksomheder er mindre patentaktive, og at de teknologisk taber terræn i forhold til deres udenlandske konkurrenter. Nærværende artikel belyser udviklingen i såvel patentaktiviteten som de anvendte ressourcer til forskning...

  10. Humor er en alvorlig sag

    DEFF Research Database (Denmark)

    Søltoft, Pia


    I modsætning til ironi er humor for Kierkegaard fællesskabsgivende – ironikeren hævder sig selv, men humoristen har sympati med den, man ler med. Humor er hos Kierkegaard udtryk for, at humoristen forliger sig med tilværelsen og dens luner, og dermed grænser humoren hos Kierkegaard op til det...

  11. Preliminary studies on (177)Lu-labeled sodium pyrophosphate (177Lu-PYP) as a potential bone-seeking radiopharmaceutical for bone pain palliation. (United States)

    Abbasi, Imtiaz Ahmed


    (99m)Tc-Sn-PYP (Technetium-99(m) labeled tin pyrophosphate) has been widely used as a radiopharmaceutical for bone scanning as well as in nuclear cardiology. It is also found in the body in trace amounts. (177)Lu is presently considered as an excellent radionuclide for developing bone pain palliation agents. PYP is an analogue of MDP and MDP has been labeled with (177)Lu. No study on preparing a complex of (177)Lu with PYP has been reported yet. Based on these facts, it was hypothesized that a bone-seeking (177)Lu-PYP (Lutetium-177 labeled Pyrophosphate) radiopharmaceutical could be developed as an agent for palliative radiotherapy of bone pain due to skeletal metastases. (177)Lu was produced by irradiating lutetium foil (11 mg) natural target at a flux ∼1.0×10(14)n/cm(2)/s for 12 h in the swimming pool type reactor. (177)Lu in the form of (177)LuCl(3) was labeled with PYP. The radiochemical purity and labeling efficiencies were determined by paper chromatography. Labeling of (177)Lu with PYP was optimized and a labeled sample was subjected to HPLC analysis. To determine the charge on the (177)Lu-PYP complex, radio-electrophoresis was conducted for 1 h under a voltage of 300 V and 45 mA current using 0.025 M phosphate buffer (pH 6.9). Bioevaluation studies with rabbit under γ-camera were also performed to verify the skeletal uptake. The quality control using paper radio-chromatography has shown >99% radiochemical purity of (177)Lu-PYP complex. Radio-chromatography also showed maximum labeling at ligand/metal ratio=60:1. HPLC analysis showed 1.42±0.01 min retention time of (177)Lu-PYP complex. No decrease in labeling was observed at higher temperatures. Gamma-camera images of (177)Lu-PYP in normal rabbit at 24 h post injection also showed high skeletal uptake. The study demonstrated that sodium pyrophosphate could be labeled with (177)Lu with high radiochemical yields (>99%). Negatively charged (177)Lu-PYP complex retained stability for a day and at high

  12. Tessellation of SoHO Magnetograms

    Indian Academy of Sciences (India)

    ... flux concentrations in solar and heliospheric observatory (SoHO) magnetograms. The mean absolute flux and size of the concentrations at the considered scale is found to be about 1.7 × 1018Mx and 5.2Mm for both polarities. The form of the flux distribution is characterized by a skewness of 3 = 4.9 and a kurtosis of 4, ...

  13. Tessellation of SoHO Magnetograms

    Indian Academy of Sciences (India)


    trations in solar and heliospheric observatory (SoHO) magnetograms. The mean absolute flux and size of the concentrations at the considered scale is found to be about 1.7 × 1018Mx and 5.2Mm for both polarities. The form of the flux distribution is characterized by a skewness of α3 = 4.9 and a kurtosis of α4, = 42.8. The fall ...

  14. High-power, hybrid Er:fiber/Tm:fiber frequency comb source in the 2 {\\mu}m wavelength region


    Adler, Florian; Diddams, Scott A.


    We present a 2-\\mum frequency comb based on a reliable mode-locked Er:fiber laser with 100 MHz repetition rate. After shifting the spectrum of the amplified Er:fiber comb to longer wavelengths, a single-clad Tm/Ho:fiber is used as a self-pumped pre-amplifier to generate a coherent and broadband spectrum centered at 1.93 \\mum. Subsequently, a cladding-pumped Tm:fiber amplifier boosts the system to a maximum output power of 4.8 W at 1.96 \\mum. After compression in a compact grating compressor, ...

  15. Profesionální poranění středního zdravotnického personálu v nemocnicích Ústeckého kraje


    KRÁTKÁ, Hana


    The reason for choosing "Occupational Injuries of Medium-Level Medical Personnel in Hospitals in the Region of Ústí nad Labem" as the topic of my master's degree stems from the fact that I have already inquired into this topic in my bachelor's thesis. Work-related injuries of hospital nurses are an interesting and important issue. Therefore, my aim was to explore this currently very up-to-date and crucial topic in greater detail, to map the level of legislative knowledge among nurses working ...

  16. The Romanian Căluş: Symbol of National Identity

    Directory of Open Access Journals (Sweden)

    Camelia Firică


    Full Text Available Of all Romanian dances with ritual functions the most archaic and dynamic is the căluş, a custom of great complexity in its functionality and manifestation, in which dance prevails. Over the course of time, the dance aroused the admiration and interest of many scholars due to the ancient ritual elements it contains, as well as for its spectacular virtuosity and the beauty of the performance and music. The purpose of this study is to reveal the meanings and functions of the căluş, primarily at the social level, in its natural environment – the traditional Romanian village – and to make an analysis of the key moments, the logical order of the dance sequences, gestures and ritual acts, the importance of its props and of group composition and organisation.

  17. Uniform, luminescent Eu:LuF{sub 3} nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Becerro, Ana I., E-mail:; Gonzalez-Mancebo, Daniel; Ocaña, Manuel [Instituto de Ciencia de Materiales de Sevilla (CSIC-University of Seville) (Spain)


    A simple procedure for the synthesis of orthorhombic, uniform, LuF{sub 3} particles with two different morphologies (rhombus- and cocoon-like) and nanometer and sub-micrometer size, respectively, is reported. The method consists in the aging, at 120 °C for 2 h, a solution containing [BMIM]BF{sub 4} ionic liquid (0.5 mL) and lutetium acetate (in the case of the rhombi) or lutetium nitrate (in the case of the cocoons) (0.02 M) in ethylene glycol (total volume 10 mL). This synthesis method was also adequate for the synthesis of Eu{sup 3+}-doped LuF{sub 3} particles of both morphologies, whose luminescence properties were investigated in detail. The experimental observations reported herein suggest that these materials are suitable phosphors for optoelectronic as well as in vitro biotechnological applications.

  18. LuAG:Ce fibers for high energy calorimetry

    CERN Document Server

    Dujardin, C; Ledoux, G; Perrodin, D; Ovanesyan, K L; Amans, D; Abler, D; Petrosyan, A; Auffray, E; Mancini, C


    The main objective of this contribution is to point out the potentialities of cerium doped LuAG single crystal as pixels and fibers. We first show that after optimization of growth conditions using Bridgman technology, this composition exhibits very good performances for scintillating applications (up to 26 000 photons/MeV). When grown with the micropulling down technology, fiber shapes can be obtained while the intrinsic performances are preserved. For the future high energy experiments requiring new detector concepts capable of delivering much richer informations about x- or gamma-ray energy deposition, unusual fiber shaped dense materials need to be developed. We demonstrate in this frame that cerium doped LuAG is a serious candidate for the next generation of ionizing radiation calorimeters. (C) 2010 American Institute of Physics. {[}doi: 10.1063/1.3452358

  19. The Romanian Căluş: Symbol of National Identity

    Directory of Open Access Journals (Sweden)

    Camelia Firică


    Full Text Available Of all Romanian dances with ritual functions the most archaic and dynamic is the căluş, a custom of great complexity in its functionality and manifestation, in which dance prevails. Over the course of time, the dance aroused the admiration and interest of many scholars due to the ancient ritual elements it contains, as well as for its spectacular virtuosity and the beauty of the performance and music. The purpose of this study is to reveal the meanings and functions of the căluş, primarily at the social level, in its natural environment – the traditional Romanian village – and to make an analysis of the key moments, the logical order of the dance sequences, gestures and ritual acts, the importance of its props and of group composition and organisation.

  20. Excitation and De-Excitation Mechanisms of Er-Doped GaAs and A1GaAs. (United States)


    Dysprosium Dy 4f106.2 1.10 0.908 67 Holmium Ho 4f 11652 1.10 0.894 68 Erbium Er 4f12632 1.11 0.881 69 Thulmium Tm 4f 136s 2 1.11 0.869 70 Ytterbium Yb...Resonance ( ESR ) experiments (52) also support this claim since they reveal that the Yb• occupies a site of tetrahedral symmetry, and that the Yb 2+ acceptor

  1. Randomized LU decomposition: An Algorithm for Dictionaries Construction


    Rotbart, Aviv; Shabat, Gil; Shmueli, Yaniv; Averbuch, Amir


    In recent years, distinctive-dictionary construction has gained importance due to his usefulness in data processing. Usually, one or more dictionaries are constructed from a training data and then they are used to classify signals that did not participate in the training process. A new dictionary construction algorithm is introduced. It is based on a low-rank matrix factorization being achieved by the application of the randomized LU decomposition to a training data. This method is fast, scal...

  2. Development of 177Lu-phytate Complex for Radiosynovectomy

    Directory of Open Access Journals (Sweden)

    Hassan Yousefnia


    Full Text Available Objective(s: In this work a new possible agent for radiosynovectomy has been targeted for articular pain palliation. Materials and Methods: Lu-177 of 2.6-3 GBq/mg specific activity was obtained by irradiation of natural Lu2O3 sample with thermal neutron flux of 4 × 1013 The product was converted into chloride form which was further used for labeling of 177Lu-phytate complex and checked using ITLC (MeOH: H2O: acetic acid, 4: 4: 2, as mobile phase. The complex stability and viscosity were checked in the final solution up to seven days. The prepared complex solution (100 µCi/100 µl was injected intra-articularly to male rat knee joint. Leakage of radioactivity from injection site and its distribution in organs were investigated up to seven days. Results: The complex was successfully prepared with high radiochemical purity (>99.9 %. Approximately, the whole injected dose has remained in injection site seven days after injection. Conclusion: The complex was proved to be a feasible agent for cavital radiotherapy in oncology and rheumatology

  3. Automatic Blocking Of QR and LU Factorizations for Locality

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Q; Kennedy, K; You, H; Seymour, K; Dongarra, J


    QR and LU factorizations for dense matrices are important linear algebra computations that are widely used in scientific applications. To efficiently perform these computations on modern computers, the factorization algorithms need to be blocked when operating on large matrices to effectively exploit the deep cache hierarchy prevalent in today's computer memory systems. Because both QR (based on Householder transformations) and LU factorization algorithms contain complex loop structures, few compilers can fully automate the blocking of these algorithms. Though linear algebra libraries such as LAPACK provides manually blocked implementations of these algorithms, by automatically generating blocked versions of the computations, more benefit can be gained such as automatic adaptation of different blocking strategies. This paper demonstrates how to apply an aggressive loop transformation technique, dependence hoisting, to produce efficient blockings for both QR and LU with partial pivoting. We present different blocking strategies that can be generated by our optimizer and compare the performance of auto-blocked versions with manually tuned versions in LAPACK, both using reference BLAS, ATLAS BLAS and native BLAS specially tuned for the underlying machine architectures.

  4. Incorporation of Pr into LuAG ceramics (United States)

    Marchewka, M. R.; Chapman, M. G.; Qian, H.; Jacobsohn, L. G.


    An investigation of the effects of Pr in (Lu1-xPrx)3Al5O12 (LuAG:Pr) ceramics was carried out by means of x-ray diffraction (XRD), energy dispersive x-ray spectroscopy (EDX), and attenuated total reflection Fourier transform infrared spectroscopy (ATR FTIR) measurements coupled with luminescence measurements. It was found that the Pr concentration that maximizes luminescence emission depends on the thermal processing conditions. While the calcined LuAG:Pr powder showed maximum luminescence emission for Pr concentrations between 0.18 and 0.33 at.%, maximum emission of ceramic bodies sintered at 1500 °C for 20 h was obtained with Pr concentrations between 0.018 and 0.18 at.%. Further, for short sintering times up to about 3 h, luminescence emission intensity is maximum for Pr concentrations around 0.33 at.%. Longer sintering times lead to the formation of PrAlO3 as a secondary phase, concomitant with a reduction of the intensity of luminescence emission.

  5. Differential nephron HO-1 expression following glomerular epithelial cell injury. (United States)

    Datta, Prasun K; Reddy, Sreenivas; Sharma, Mukut; Lianos, Elias A


    In proteinuria of glomerular origin there is upregulation of heme-oxygenase (HO), the rate-limiting enzyme of heme degradation, in the nephron in a segment-specific manner. To better characterize this phenomenon, we employed a model of proteinuria resulting from disruption of the glomerular capillary permeability barrier to protein by administration of the glomerular epithelial cell toxin puromycin aminonucleoside (PAN) to rats. In this model, we assessed nephron distribution of the expression of the inducible HO isoform, HO-1, and the role of free radicals in modulating HO-1 expression. Rats were injected with either vehicle (dimethyl sulfoxide) or PAN or the spin trap free radical stabilizer alpha-phenyl-N-tert butyl nitrone (PBN), or with both PAN and PBN. Ten days following the PAN injection, urine protein, creatinine, nitric oxide (NO) and malonyldialdehyde (MDA) were measured. Kidney sections and protein lysates were assessed for changes in HO-1 expression by immunohistochemistry and Western blot analysis. In control animals (DMSO or PBN alone) there was no proteinuria and very weak or absent HO-1 staining in nephron segments. PAN treatment induced proteinuria and increased urine MDA excretion. In these animals, there was a robust HO-1 expression mainly in tubules and in glomerular parietal but not visceral epithelial cells. Unilateral ureteral obstruction to interrupt glomerular filtration in animals treated with PAN abrogated tubular HO-1 expression in the kidney ipsilateral to the obstruction. Administration of PBN to PAN-treated animals reduced proteinuria and MDA excretion while it markedly augmented tubular HO-1 expression. This augmentation was prominent in tubular cells of the inner cortex/outer medulla. These observations indicate that upregulation of nephron HO-1 following disruption of the glomerular permeability barrier occurs at sites downstream of this barrier and is mediated by a filtered HO-1 inducer(s). Scavenging of free radicals potentiates

  6. Design průmyslového planetového mixéru


    Škodová, Nina


    Diplomová práce je zaměřena na design průmyslového planetového mixéru o objemu díže 40 litrů. Cílem je vytvoření designu zohledňující ergonomii a konstrukční a technologické požadavky. The diploma thesis is focused on the design of an industrial planetary mixer with a volume of 40 liters. The goal is to create a design that takes account of ergonomics and design and technology requirements. C

  7. Encapsulation of a radiolabeled cluster inside a fullerene cage, (177)Lu(x)Lu((3-x))N@C(80): an interleukin-13-conjugated radiolabeled metallofullerene platform. (United States)

    Shultz, Michael D; Duchamp, James C; Wilson, John D; Shu, Chun-Ying; Ge, Jiechao; Zhang, Jianyuan; Gibson, Harry W; Fillmore, Helen L; Hirsch, Jerry I; Dorn, Harry C; Fatouros, Panos P


    In this communication, we describe the successful encapsulation of (177)Lu into the endohedral metallofullerene (177)Lu(x)Lu(3-x)N@C(80) (x = 1-3) starting with (177)LuCl(3) in a modified quartz Kraschmer-Huffman electric generator. We demonstrate that the (177)Lu (beta-emitter) in this fullerene cage is not significantly released for a period of up to at least one-half-life (6.7 days). We also demonstrate that this agent can be conjugated with an interleukin-13 peptide that is designed to target an overexpressed receptor in glioblastoma multiforme tumors. This nanoparticle delivery platform provides flexibility for a wide range of radiotherapeutic and radiodiagnostic multimodal applications.

  8. Renovering er en vigtig arkitektonisk opgave

    DEFF Research Database (Denmark)

    Bech-Danielsen, Claus


    Renovering af almene boliger er et stort og voksende arbejdsfelt. Der er tale om en vigtig arkitektonisk opgave, der er både spændende og fagligt udfordrende. Udgivelsesdato: juni......Renovering af almene boliger er et stort og voksende arbejdsfelt. Der er tale om en vigtig arkitektonisk opgave, der er både spændende og fagligt udfordrende. Udgivelsesdato: juni...

  9. Primary standardization of a {sup 177}Lu solution; Padronizacao primaria de uma solucao de {sup 177}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Iwahara, Akira; Silva, Carlos Jose da; Tauhata, Luiz; Oliveira, Estela Maria de, E-mail:, E-mail:, E-mail:, E-mail: [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil); Rezende, Eduarda Alexandre, E-mail: [Centro Federal de Educacao Tecnologica de Quimica (CEFET), Nilopolis, RJ (Brazil)


    For the purpose to make available reliable standards of {sup 177}Lu to the users and producers, a radionuclide solution was standardized using the primary methods of coincidence 4{pi}{beta}(PC)-{gamma}(NaI(Tl)) and of 4{pi}{beta}(LS)-{gamma}(NaI(Tl)). The results presented a convergence in the range of evaluated uncertainties. The standard uncertainties were of the 0.50 and 0.74% for the anticoincidence and coincidence respectively


    Directory of Open Access Journals (Sweden)

    Pebriana Marlinda


    Full Text Available Abstrak :            Penelitian tentang pengendalian dalam penerbitan izin gangguan (HO di Kecamatan Margahayu Kabupaten Bandung menjelaskan tentang tahap-tahap pengendalian yang dilakukan oleh aparat Kecamatan Margahayu. Pengendalian dilakukan untuk memastikan agar penerbitan izin gangguan (HO berjalan dengan efektif. Namun, masih ada pelaku usaha yang belum memiliki surat izin gangguan (HO ataupun pelaku usaha yang sudah memiliki surat izin gangguan (HO akan tetapi kegiatan usahanya merugkan orang lain seperti sampah yang berserakan, polusi udara, polusi suara, dan lain-lain.                            Metode penelitian yang digunakan adalah metode penelitian deduktif kualitatif dengan teknik pengumpulan data melalui studi kepustakaan dan studi lapangan yang meliputi observasi dan wawancara mendalam. Adapun penentuan informan dalam penelitian ini dipilih berdasarkan pertimbangan-pertimbangan dengan pihak-pihak yang terkait dalam pengendalian. Kemudian data yang diperoleh dari hasil wawancara dipaparkan dengan langkah-langkah yang meliputi: reduksi data, penyajian data, menarik kesimpulan/verifikasi. Teori yang digunakan penulis dalam penelitian ini adalah teori dari Stephen P. Robbins tentang tahap-tahap pengendalian yaitu: mengukur kinerja aktual, membandingkan kinerja aktual dengan standar, dan mengambil tindakan manajerial.                            Kesimpulan dari hasil penelitian ini adalah pengendalian yang dilakukan olehaparat Kecamatan Margahayu telah melalui tahap-tahap pengendalian yaitu: mengukur kinerja aktual, membandingkan kinerja aktual dengan standar, dan mengambil tindakan manajerial. Namun perlu dilakukan penguatan di setiap tahap pengendalian terutama pada tahap mengukur kinerja aktual dan pada tahap mengambil tindakan manajerial                            Penelitian tentang pengendalian dalam penerbitan izin gangguan (HO di Kecamatan

  11. Měření diverzitního vysílání ve standardu DVB-T2


    Koblischka, Vítězslav


    Bakalářská práce porovnává standardy pro digitální pozemní televizní vysílání první generace DVB-T a druhé generace DVB-T2. Zaměřuje se zejména na vliv rušení přenosového prostředí simulovaný přenosovými kanály pro pevný, přenosný a mobilní příjem pozemního digitálního signálu. Dále práce porovnává SISO vysílání s diverzitním vysíláním MISO ve standardu DVB-T2 a vyhodnocuje vliv módu na chybovost v závislosti na zvoleném přenosovém kanále a použitých systémových parametrech. This bachelor ...

  12. Automatické generování pozic optického skeneru pro digitalizaci plechových dílů


    Koutecký, Tomáš


    Práce se zabývá návrhem metodiky pro automatické generování pozic optického skeneru pro digitalizaci plechových dílů na základě počítačového modelu měřenéholu. Výroba a s tím související inspekce plechových dílů jsou velmi úzce spojeny s automobilním průmyslem. Kvůli obecným zvyšujícím se nárokům na přesnost je v sériové výrobě kladen požadavek na přesnou kontrolu vyráběných dílů. K tomu se stále častěji začínají využívat optické 3D skenery a průmyslové roboty. V případě zavedení výroby no...

  13. Observation and modelling of OH and HO2 concentrations in Beijing and Pearl River Delta summer 2006: missing OH source in VOC rich atmosphere (United States)

    Lu, K.; Rohrer, F.; Holland, F.; Fuchs, H.; Bohn, B.; Brauers, T.; Chang, C.; Hu, M.; Kita, K.; Kondo, Y.; Li, X.; Lou, S.; Oebel, A.; Shao, M.; Zeng, L.; Zhu, T.; Wahner, A.; Zhang, Y.; Hofzumahaus, A.


    Ambient OH and HO2 concentrations were measured by laser induced fluorescence (LIF) during the PRIDE-PRD2006 (Program of Regional Integrated Experiments of Air Quality over the Pearl River Delta, 2006) and the CAREBEIJING2006 (Campaigns of Air Quality Research in Beijing and Surrounding Region, 2006) campaigns at rural sites close to the megacities of Guangzhou and Beijing, respectively. In PRD, the observed daily maximum OH and HO2 concentrations reached daily peak values of (15~--~26)±106 cm-3 and (3~--~25)±108 cm-3, respectively. In Beijing, the corresponding values were about (4~--~17)±106 cm-3 and (2~--~24)±108 cm-3. At both sites, the measured OH concentrations were much higher than can be explained by current chemical box models when NOx is low, pointing to a missing OH source in VOC rich air. In this presentation, we report the observed and modelled HOx concentrations, depict the general feature of the HOx system through an empirical analysis, and examine different mechanistic proposals to explain the missing OH source (Hofzumahaus et al. 2009; Lu et al., 2011). Overall, we conclude that a missing OH recycling of type HO2->OH is required for these VOC rich air masses in the transient regime between biogenic and urban influences. Recently published mechanistic updates of isoprene chemistry (e.g. MIM2+ and LIM0) developed for forest regions are not able to reproduce the observed OH in both PRD and Beijing.

  14. Min mentor er min voksenven

    DEFF Research Database (Denmark)

    Kaiser, Birte


    En artikel i bogen: 6 belysninger af vejledning, brydninger, forståelser & praksis. Artiklen er et sammendrag af en diskursanalyse fra 2008 fra projetrapporten: Ind under huden,

  15. Comparison of the emission properties of Ho 3+ :KPb 2 Cl 5 and Ho ...

    African Journals Online (AJOL)

    properties of Ho3+ doped low phonon halides (KPb2 Cl 5 ) with those of their fluoride counterparts. Results show 2 5 that mid-IR emission wavelengths that appeared in the halide hosts were effectively quenched in the fluorides. Furthermore, the emission lifetimes of the halides did not vary significantly with temperature, ...

  16. Forenklingens fire F'er

    DEFF Research Database (Denmark)

    Bentzen, Tina Øllgaard


    At fjerne styring er det, man ofte forbinder med afbureaukratisering, men det er ikke tilstrækkeligt, når man vil gå fra flotte ambitioner til en styring, som reelt opleves enklere. For at forenkle må man også forandre, forankre og fastholde styring, og det må ske i et samspil mellem de aktører, ...

  17. The role of phosphates for the Lu-Hf chronology of meteorites (United States)

    Debaille, Vinciane; Van Orman, James; Yin, Qing-Zhu; Amelin, Yuri


    The 176Lu-176Hf isotopic system is widely used for dating and tracing cosmochemical and geological processes, but still suffers from two uncertainties. First, Lu-Hf isochrons for some early Solar System materials have excess slope of unknown origin that should not be expected for meteorites with ages precisely determined with other isotopic chronometers. This observation translates to an apparent Lu decay constant higher than the one calculated by comparing ages obtained with various dating methods on terrestrial samples. Second, unlike the well constrained Sm/Nd value (to within 2%) for the chondritic uniform reservoir (CHUR), the Lu/Hf ratios in chondrites vary up to 18% when considering all chondrites, adding uncertainty to the Lu/Hf CHUR value. In order to better understand the Lu-Hf systematics of chondrites, we analyzed mineral fractions from the Richardton H5 chondrite to construct an internal Lu-Hf isochron, and set up a numerical model to investigate the effect of preferential diffusion of Lu compared to Hf from phosphate, the phase with the highest Lu-Hf ratio in chondrites, to other minerals. The isochron yields an age of 4647 ± 210 million years (Myr) using the accepted 176Lu decay constant of 1.867 ± 0.008 ×10-11yr-1. Combining this study with the phosphate fractions measured in a previous study yields a slope of 0.08855 ± 0.00072, translating to a 176Lu decay constant of 1.862 ± 0.016 ×10-11yr-1 using the Pb-Pb age previously obtained, in agreement with the accepted value. The large variation of the Lu/Hf phosphates combined with observations in the present study identify phosphates as the key in perturbing Lu-Hf dating and generating the isochron slope discrepancy. This is critical as apatite has substantially higher diffusion rates of rare earth elements than most silicate minerals that comprise stony meteorites. Results of numerical modeling depending of temperature peak, size of the grains and duration of the metamorphic event, show that

  18. Theranostic Treatment of Metastatic Bone Pain With 177Lu-DOTMP. (United States)

    Das, Tapas; Shinto, Ajit; Karuppuswamy Kamaleshwaran, Koramadai; Banerjee, Sharmila


    Radiochemical studies and biological evaluation in animal models have shown superior radiochemical properties and better clearance pattern for Lu-DOTMP compared with Lu-EDTMP, an agent recently proven to be efficacious and safe for metastatic bone pain palliation. This prompted us to initiate the clinical evaluation of Lu-DOTMP. The images represent the whole-body scans of a prostate cancer patient (man, 67 years) with skeletal metastases recorded after administering 3.7 GBq (100 mCi) of Lu-DOTMP.

  19. The Role of HO(x) in Super- and Subsonic Aircraft Exhaust Plumes (United States)

    Hanisco, T. F.; Wennberg, P. O.; Cohen, R. C.; Anderson, J. G.; Fahey, D. W.; Keim, E. R.; Gao, R. S.; Wamsley, R. C.; Donnelly, S. G.; DelNegro, L. A.; hide


    The generation of sulfuric acid aerosols in aircraft exhaust has emerged as a critical issue in determining the impact of supersonic aircraft on stratospheric ozone. It has long been held that the first step in the mechanism of aerosol formation is the oxidation of SO2 emitted from the engine by OH in the exhaust plume. We report in situ measurements of OH and HO2 in the exhaust plumes of a supersonic (Air France Concorde) and a subsonic (NASA ER-2) aircraft in the lower stratosphere. These measurements imply that reactions with OH are responsible for oxidizing only a small fraction of SO2 (2%), and thus cannot explain the large number of particles observed in the exhaust wake of the Concorde.

  20. Spontaneous laser-line sweeping in Ho-doped fiber laser (United States)

    Aubrecht, Jan; Peterka, Pavel; Koška, Pavel; Honzátko, Pavel; Jelínek, Michal; Kamrádek, Michal; Frank, Milan; Kubeček, Václav; Kašík, Ivan


    Spontaneous laser-line sweeping refers to fiber laser instabilities with regular laser wavelength drift within a broad range that may exceed 10 nm; other characteristics of the laser output are sustained relaxation self-pulsing and narrow spectral linewidth. The laser wavelength drift is caused by standing-wave in the cavity; it can be regarded as a special case of mode instability of longitudinal modes of the laser resonator. Self-sweeping was observed so far in Yb, Er, Tm and Bidoped fiber lasers. We report on Ho-doped fiber laser self-sweeping in interval of 3-5 nm near 2100 nm. The sweeping rate was typically 0.7-0.9 nm/s. The thulium-doped fiber lasers at around 2030 nm and 1950 nm were tested as pump sources. The self-sweeping was registered by FTIR spectrometer and the data processing is discussed.

  1. Efficient up-conversion in Yb:Er:NaT(XO42 thermal nanoprobes. Imaging of their distribution in a perfused mouse.

    Directory of Open Access Journals (Sweden)

    Carlos Zaldo

    Full Text Available Yb and Er codoped NaT(XO42 (T = Y, La, Gd, Lu and X = Mo, W disordered oxides show a green (Er3+ related up-conversion (UC efficiency comparable to that of Yb:Er:β-NaYF4 compound and unless 3 times larger UC ratiometric thermal sensitivity. The similar UC efficiency of Yb:Er doped NaT(XO42 and β-NaYF4 compounds allowed testing equal subcutaneous depths of ex-vivo chicken tissue in both cases. This extraordinary behavior for NaT(XO42 oxides with large cutoff phonon energy (ħω≈ 920 cm-1 is ascribed to 4F9/2 electron population recycling to higher energy 4G11/2 level by a phonon assisted transition. Crystalline nanoparticles of Yb:Er:NaLu(MoO42 have been synthesized by sol-gel with sizes most commonly in the 50-80 nm range, showing a relatively small reduction of the UC efficiency with regards to bulk materials. Fluorescence lifetime and multiphoton imaging microscopies show that these nanoparticles can be efficiently distributed to all body organs of a perfused mouse.

  2. EGR-1 regulates Ho-1 expression induced by cigarette smoke

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Huaqun, E-mail: [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210029 (China); Wang, Lijuan; Gong, Tao; Yu, Yang; Zhu, Chunhua; Li, Fen; Wang, Li [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210029 (China); Li, Chaojun, E-mail: [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Sciences, Nanjing Normal University, Nanjing 210029 (China); Model Animal Research Center (MARC) and The School of Medicine, Nanjing University, Nanjing 210095 (China)


    As an anti-oxidant molecule, heme oxygenase-1 (HO-1) has been implicated in the protection of lung injury by cigarette smoke (CS). The mechanisms regulating its expression have not been defined. In this report, the role of early growth response 1 (EGR-1) in the regulation of Ho-1 expression was investigated. In C57BL/6 mice with CS exposure, HO-1 was greatly increased in bronchial epithelial cells and alveolar inflammatory cells. In primary cultured mouse lung fibroblasts and RAW264.7 cells exposed to cigarette smoke water extract (CSE), an increase in HO-1 protein level was detected. In addition, CSE induced HO-1 expression was decreased in Egr-1 deficient mouse embryo fibroblasts (Egr-1{sup -/-} MEFs). Nuclear localization of EGR-1 was examined in mouse lung fibroblasts after exposure to CSE. Luciferase reporter activity assays showed that the enhancer region of the Ho-1 gene containing a proposed EGR-1 binding site was responsible for the induction of HO-1. A higher increase of alveolar mean linear intercept (Lm) was observed in lung tissues, and a larger increase in the number of total cells and monocytes/macrophages from bronchial alveolar lavage fluid was found in CS-exposed mice by loss of function of EGR-1 treatment. In summary, the present data demonstrate that EGR-1 plays a critical role in HO-1 production induced by CS.

  3. Sewage, Septage and faecal sludge management profile in Ho ...

    African Journals Online (AJOL)

    The paper presents the sewage, septage and faecal sludge management profile in the Ho District of Ghana. The excreta handling facilities available in Ho District are water closet systems, KVIP, pan/bucket latrines and public latrines. About 71 per cent of the population, especially people in the densely populated and low ...

  4. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis

    Directory of Open Access Journals (Sweden)

    Yingqing Chen


    Full Text Available The selective type-3 phosphodiesterase inhibitor cilostazol and the antihyperlipidemic agent probucol have antioxidative, anti-inflammatory, and antiatherogenic properties. Moreover, cilostazol and probucol can regulate mitochondrial biogenesis. However, the combinatorial effect of cilostazol and probucol on mitochondrial biogenesis remains unknown. Endoplasmic reticulum (ER stress is a well-known causative factor of nonalcoholic fatty liver disease (NAFLD which can impair mitochondrial function in hepatocytes. Here, we investigated the synergistic effects of cilostazol and probucol on mitochondrial biogenesis and ER stress-induced hepatic steatosis. A synergistic effect of cilostazol and probucol on HO-1 and mitochondrial biogenesis gene expression was found in human hepatocellular carcinoma cells (HepG2 and murine primary hepatocytes. Furthermore, in an animal model of ER stress involving tunicamycin, combinatorial treatment with cilostazol and probucol significantly increased the expression of HO-1 and mitochondrial biogenesis-related genes and proteins, whereas it downregulated serum ALT, eIF2 phosphorylation, and CHOP expression, as well as the lipogenesis-related genes SREBP-1c and FAS. Based on these results, we conclude that cilostazol and probucol exhibit a synergistic effect on the activation of mitochondrial biogenesis via upregulation of HO-1, which confers protection against ER stress-induced hepatic steatosis.

  5. K2Ho(PO4(WO4

    Directory of Open Access Journals (Sweden)

    Katherina V. Terebilenko


    Full Text Available A new compound, dipotassium holmium(III phosphate(V tungstate(VI, K2Ho(PO4(WO4, has been obtained during investigation of the K2O–P2O5–WO3–HoF3 phase system using the flux technique. The compound is isotypic with K2Bi(PO4(WO4. Its framework structure consists of flat ∞2[HoPO4] layers parallel to (100 that are made up of ∞1[HoO8] zigzag chains interlinked via slightly distorted PO4 tetrahedra. WO4 tetrahedra are attached above and below these layers, leaving space for the K+ counter-cations. The HoO8, PO4 and WO4 units exhibit 2 symmetry.

  6. Synthesis, stabilization and formulation of [{sup 177}Lu]Lu-AMBA, a systemic radiotherapeutic agent for Gastrin Releasing Peptide receptor positive tumors

    Energy Technology Data Exchange (ETDEWEB)

    Chen Jianqing [Bracco Research USA Inc., 305 College Road East, Princeton, NJ 08540 (United States); Linder, Karen E. [Bracco Research USA Inc., 305 College Road East, Princeton, NJ 08540 (United States)], E-mail:; Cagnolini, Aldo; Metcalfe, Edmund; Raju, Natarajan; Tweedle, Michael F.; Swenson, Rolf E. [Bracco Research USA Inc., 305 College Road East, Princeton, NJ 08540 (United States)


    A robust formulation was developed for [{sup 177}Lu]Lu-AMBA ({sup 177}Lu-DO3A-CH{sub 2}CO-G-[4-aminobenzoyl]-QWAVGHLM-NH{sub 2}), a Bombesin-like agonist with high affinity for Gastrin Releasing Peptide (GRP) receptors. During optimization of labeling, the effect of several radiostabilizers was evaluated; a combination of selenomethionine and ascorbic acid showed superiority over other tested radiostabilizers. The resulting two-vial formulation maintains a radiochemical purity (RCP) of >90% for at least 2 days at room temperature. The method of stabilization should be useful for other methionine-containing peptide radiopharmaceuticals in diagnostic and therapeutic applications.

  7. Lu-177 DOTATATE dosimetry for neuroendocrine tumor: single center experience (United States)

    Said, MA; Masud, MA; Zaini, MZ; Salleh, RA; Lee, BN; Zainon, R.


    Lu-177 labelled with DOTATE is widely acceptable to treat Neuroendocrine Tumor (NET) disease and it better improvement of quality of patients’ life since few years ago. However, the radionuclide toxicity becomes the main limitation of the (NET) treatment. Therefore, we performed a pilot study aimed to estimate radiation absorbed doses to dose-limiting organs to develop a systemic therapy with Lu-177 in NET patients. In this study, five set of planar whole body images was acquired every 0.5 hour, 4 hours, 24 hours, 48 hours and 72 hours after Lu-177 administrations. The planar image acquisition was done using Philip Brightview X with Medium Energy General Purpose Collimator (MEGP) collimator. All patients’ images in Conjugate View (CV) format were transferred into PMOD 3.7 Software for Region of Interest (ROI) analysis. The ROI were drawn at selected organs such as kidneys, liver, spleen and bladder. This study found that the mean absorbed dose for kidneys 0.62 ± 0.26 Gy/GBq, liver 0.63 ± 0.28 Gy/GBq, spleen 0.83 ± 0.73 Gy/GBq and bladder 0.14 ± 0.07 Gy/GBq. The radionuclide kinetic for the whole body 99.7 ± 0.1 percent at 0.5 hours, 79.5 ± 10.7 percent at 4 hours, 56.6 ± 10.3 percent at 24 hours, 43.2 ± 7.9 percent at 48 hours and 37.1 ± 9.0 percent at 72 hours. This study verifies that this planar quantitative method able to determine organ at risk and the result line with other published data.



    Katı, Yasemin


    Literature, which nourish the soul and educate the people, is one of the branch of art. Yavuz Bahadıroğlu is one of the literateur of our time who wri-tes stories appealing the children’s soul and contributing to the education.In his stories, abstract concepts are used; themes such as love, friendship, co-operation, helping, health etc were examined. The love of family, friends and school, cooperation, helping each other and topics like them were chosen. The writer wrote his books with a plai...

  9. A Supernodal Approach to Incomplete LU Factorization with Partial Pivoting

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoye Sherry; Shao, Meiyue


    We present a new supernode-based incomplete LU factorization method to construct a preconditioner for solving sparse linear systems with iterative methods. The new algorithm is primarily based on the ILUTP approach by Saad, and we incorporate a number of techniques to improve the robustness and performance of the traditional ILUTP method. These include the new dropping strategies that accommodate the use of supernodal structures in the factored matrix. We present numerical experiments to demonstrate that our new method is competitive with the other ILU approaches and is well suited for today's high performance architectures.

  10. Screening af kulturmiljøer

    DEFF Research Database (Denmark)


    Arkitektskolen Aarhus sætter fokus på kulturmiljøer i Danmarks yderområder. Screening af Kulturmiljøer (SAK) er et redskab til at vurdere kulturmiljøer ud fra aflæselige parametre, så kulturarvens værdier, egenskaber og udviklingspotentialer bliver synlige. Formålet er at skabe nye muligheder og...

  11. Continuous-Wave and Actively Q-Switched Diode-Pumped Er:LuAG Ring Laser at 1650 nm (United States)

    Tong-Yu, Dai; Xu-Guang, Xu; Lin, Ju; Jing, Wu; Zhen-Guo, Zhang; Bao-Quan, Yao; Ye, Zhang


    Not Available Supported by the National Natural Science Foundation of China under Grant Nos 61308009 and 61405047, the China Postdoctoral Science Foundation Funded Project under Grant No 2013M540288, the Fundamental Research Funds for the Central Universities under Grant Nos HIT.NSRIF.2014044 and HIT.NSRIF.2015042, the Science Fund for Outstanding Youths of Heilongjiang Province under Grant No JQ201310, and the Heilongjiang Postdoctoral Science Foundation Funded Project under Grant No LBH-Z14085.

  12. 177-lu labeled peptide for site-specific uPAR-targeting

    DEFF Research Database (Denmark)


    There is provided a 177-Lu labelled peptide for site-specific targeting of the Urokinase Plasminogen Activator Receptor (uPAR) thereby enabling treatment of a cancer disease associated with high uPAR expression; e.g. treatment of colorectal cancer by administering to a patient an effective amount...... of the 177-Lu labelled peptide....

  13. Beta-glycosidase (amygdalase and linamarase) from Endomyces fibuliger (LU677): formation and crude enzymes properties.

    NARCIS (Netherlands)

    Brimer, L.; Nout, M.J.R.; Tuncel, G.


    In our previous studies, the yeast Endomyces fibuliger LU677 was found to degrade amygdalin in bitter apricot seeds. The present investigation shows that E. fibuliger LU677 produces extracellular beta-glycosidase activity when grown in malt extract broth (MEB). Growth was very good at 25 degrees C

  14. Effects of therapy with [177Lu-DOTA0,Tyr 3]octreotate on endocrine function

    NARCIS (Netherlands)

    J.J.M. Teunissen (Jaap); E.P. Krenning (Eric); F.H. de Jong (Frank); Y.B. de Rijke (Yolanda); R.A. Feelders (Richard); M.O. van Aken (Maarten); W.W. de Herder (Wouter); D.J. Kwekkeboom (Dirk Jan)


    textabstractPurpose: Peptide receptor radionuclide therapy (PRRT) with radiolabelled somatostatin analogues is a novel therapy for patients with somatostatin receptor-positive tumours. We determined the effects of PRRT with [177Lu-DOTA0,Tyr3]octreotate (177Lu-octreotate) on glucose homeostasis and

  15. Whole Body Activity Retentions in the Peptide Receptor Radionuclide Therapy with Lu-177

    NARCIS (Netherlands)

    Liu, B.


    The patients with the neuroendocrine tumours (liver, spleen, etc.) often need treatment by the Peptide Receptor Radionuclide Therapy with 177Lu. The amount of 177Lu activity in the body of patients has to be known accurately for assessment of the dosimetry and for evaluation of the effectiveness of

  16. Effect of Electron Traps on Scintillation of Praseodymium Activated Lu3Al5O12

    NARCIS (Netherlands)

    Drozdowski, W.; Dorenbos, P.; Drozdowska, R.; Bos, A.J.J.; Poolton, N.R.J.; Tonelli, M.; Alshourbagy, M.


    In this paper we present the studies performed on a set of Lu3Al5O12:Pr (LuAG:Pr) crystals with praseodymium concentration between 1.5 and 10%, grown by the micro-pulling-down (muPD) technique. The research comprises the measurements of X-ray excited emission spectra and 137Cs gamma-ray pulse height

  17. Borgeren er tilskuer og bruger

    DEFF Research Database (Denmark)

    Thyssen, Ole


    Siden den politiske elite blev afhængig af borgernes stemmer, har det været en fast bestanddel i enhver valgkamp, at politikere giver løfter om et bedre liv - bedre arbejde og mere velfærd. Resultatet er en kravsinflation, hvor den ene part lover, og den anden part kræver mere velfærd. Nøk for nø...... og uden en samlet plan er velfærden og staten blevet slået af elefantiasis....

  18. Foregribende sorg er ikke forebyggende

    DEFF Research Database (Denmark)

    Nielsen, Mette Kjærgaard; Thomsen, Kia Toft; Jensen, Anders Bonde


    Baggrund: Betydningen af pårørendes sorgsymptomer før tid, tidligere kaldet foregribende sorg, er uklar. Materiale og metode: En landsdækkende spørgeskemaundersøgelse af 3635 pårørende til patienter med terminaltilskud i 2012. Resultater: Mange symptomer på sorg før død havde sammenhæng med kompl...... kompliceret sorgreaktion efter dødsfaldet samt faktorer i det palliative forløb. Fortolkning: Sorg før dødsfaldet har sammenhæng med forværret sorgreaktion; foregribende sorg er misvisende....

  19. Kemalismen er truet i Tyrkiet

    DEFF Research Database (Denmark)

    Østergaard, Uffe


    Historisk set. Arven efter det sekulære Tyrkiets landsfader, Mustafa Kemal Atatürk, er truet i det kulturopgør, som præsident Erdogan har iværksat efter det nylige kupforsøg.......Historisk set. Arven efter det sekulære Tyrkiets landsfader, Mustafa Kemal Atatürk, er truet i det kulturopgør, som præsident Erdogan har iværksat efter det nylige kupforsøg....

  20. High-power, hybrid Er:fiber/Tm:fiber frequency comb source in the 2 μm wavelength region. (United States)

    Adler, Florian; Diddams, Scott A


    We present a 2 μm frequency comb based on a reliable mode-locked Er:fiber laser with 100 MHz repetition rate. After shifting the spectrum of the amplified Er:fiber comb to longer wavelengths, a single-clad Tm/Ho:fiber is used as a self-pumped pre-amplifier to generate a coherent and broadband spectrum centered at 1.93 μm. Subsequently, a cladding-pumped Tm:fiber amplifier boosts the system to a maximum output power of 4.8 W at 1.96 μm. After compression in a compact grating compressor, our amplified Er:fiber/Tm:fiber hybrid system delivers as much as 2.9 W with a pulse duration of 141 fs. The system's comb properties are examined via heterodyne measurement.

  1. Konstrukce nestandardního kola


    Mihálik, Boris


    Cieľom tejto bakalárskej práce je návrh a konštrukcia chopper bicykla určeného na propagačné účely. V prvej časti je definovaný chopper bicykel a jeho vhodnosť pre propagačné účely. Druhá časť sa zaoberá koncepciou riešenia a výberom variant riešenia jednotlivých konštrukčných uzlov bicykla. Konečným návrhom konštrukcie ako aj ekonomickým zhodnotením sa zaoberá časť tretia. The aim of this bachelor work is design and construction of chopper bicycle designed for promotional purposes. The fi...

  2. Lu AA21004, a novel multimodal antidepressantwith activity exerted through serotonergic targets

    DEFF Research Database (Denmark)

    Mork, A.; Pehrson, A.; Montezinho, L. C. P.


    Background: Lu AA21004 is a multimodal antidepressant that functions as a 5-HT3 and 5-HT7 receptor antagonist, 5-HT1B receptor partial agonist, 5-HT1A receptor agonist and inhibitor of the 5-HT transporter in vitro. Here we investigated preclinical effects of Lu AA21004 1) on target occupancies, 2......) on neurotransmitter levels in the brain, 3) in an animal model of depression and 4) on cognitive processing. Methods: Lu AA21004 occupancy at the 5-HT transporter, and 5-HT1A, 5-HT1B and 5-HT3 receptors was measured ex vivo in rat brain slices. Effects of Lu AA21004 on extracellular neurotransmitter levels [serotonin...... (5-HT), noradrenaline (NA), dopamine (DA), acetylcholine (ACh), histamine (Hist)] were measured by microdialysis. Antidepressant potential was assessed in the forced swim test using Flinders Sensitive Line (FSL) rats. Moreover, effects of Lu AA21004 on acquisition, consolidation and recall...

  3. Biferroic LuCrO{sub 3}: Structural characterization, magnetic and dielectric properties

    Energy Technology Data Exchange (ETDEWEB)

    Durán, A., E-mail: [Universidad Nacional Autónoma de México, Centro de Nanociencias y Nanotecnología, Km. 107 Carretera Tijuana-Ensenada, Apartado Postal 14, C.P. 22800 Ensenada, BC (Mexico); Meza F, C.; Morán, E.; Alario-Franco, M.A. [Departamento de Química Inorgánica y Laboratorio Complutense de Altas Presiones, Facultad de Química, Universidad Complutense de Madrid, EU, 28040 Madrid (Spain); Ostos, C., E-mail: [Instituto de Química, Universidad de Antioquia UdeA, Calle 70 No. 52-21, Medellín (Colombia)


    Multiferroic LuCrO{sub 3} perovskite-type structure (Pbnm) obtained via auto-ignition synthesis was characterized by a combination of X-ray diffraction (XRD) and thermogravimetric (TG) techniques, and through magnetization and permittivity measurements. Results showed that amorphous combustion powders were fully transformed to orthorhombic LuCrO{sub 3} structure at 1200 K after the first LuCrO{sub 4} crystallization at 700 K. The magnetic response displays thermal irreversibility between zero-field-cooling and field-cooling condition which is due to spin canted AF switching at 116 K. Accordingly, a hysteresis loop in the M(H) data confirms weak ferromagnetism in LuCrO{sub 3}. On the other hand, the permittivity measurement shows a broad peak transition typical of relaxor-type ferroelectrics transition at ∼450 K. Electrical conductivity increases as temperature increases showing an anomaly around the diffuse phase transition. The diffuse phase transition and the formation of the charge carriers are discussed in terms of a local distortion around the Lu Site. - Highlights: • Multiferroic LuCrO{sub 3} was successfully obtained via auto-ignition synthesis. • Amorphous powder is transformed first to LuCrO{sub 4} (700 K) and next to LuCrO{sub 3} (1100 K). • The CrO{sub 6} octahedra are tilted away and rotates from the ideal octahedral shape. • LuCrO{sub 3} exhibits a canted AFM transition (116 K) and a relaxor ferroelectric behavior. • Tilting and rotation of CrO{sub 6} octahedra influenced transport properties on LuCrO{sub 3}.

  4. Intracluster interactions in butterfly {Fe3LnO2} molecules with the non-Kramers ions Tb(III) and Ho(III) (United States)

    Badía-Romano, L.; Rubín, J.; Bartolomé, F.; Bartolomé, J.; Luzón, J.; Prodius, D.; Turta, C.; Mereacre, V.; Wilhelm, F.; Rogalev, A.


    The intracluster exchange interactions within the "butterfly" [Fe3Ln (μ3-O )2(CCl3COO )8(H2O )(THF )3] molecules, where Ln(III) represents a lanthanide cation, have been determined by a combination of x-ray magnetic circular dichroism (XMCD) and vibrating sample magnetometry (VSM) along with an interaction model. We have studied the compounds with Ln =Tb and Ho, both non-Kramers lanthanides and with high uniaxial anisotropy, and Ln =Lu (III) and Y(III) as pseudolanthanides, which supply nonmagnetic Ln reference cases. At low temperature, the three Fe atoms can be considered as a self-unit with total spin SFe 3=5 /2 . Using the element selectivity of the XMCD magnetometry, measured at the Ln L2 ,3 edges, together with the VSM measurements, the local magnetization of the Ln ion and the Fe3 subcluster, as a function of the field and low temperature (T ≈2.5 K ), has been determined separately. These results are described quantitatively in the framework of a theoretical model based on an effective spin Hamiltonian, which considers the competing effects of intracluster interactions and the external applied magnetic field. The Ln -Fe3 exchange interaction within the {Fe3LnO2} cluster has been determined to be antiferromagnetic, in both Tb and Ho compounds, with JFeTb/kB=-0.13 (1 ) K and JFeHo/kB=-0.18 (1 ) K , respectively. In both cases, a field-induced reorientation of the Fe3 and Ln spins from antiparallel to parallel orientation takes place at a threshold field μ0H =1.1 and 2 T, for the {Fe3TbO2} and {Fe3HoO2} compounds, respectively. By comparison with other compounds of the series with uniaxial anisotropy, it is concluded that the polarizability of the Fe3 subcluster magnetic moment decreases in the trend {Fe3YO2}→{Fe3TbO2}→{Fe3HoO2}→{Fe3DyO2} , because of the increasing opposition of the exchange antiferromagnetic field caused by the Ln ion. In the Ln =Tb , Ho, and Dy, the magnetization of the whole molecule is dominated by the anisotropy of the Ln ion

  5. Ro på: Solen er stille

    DEFF Research Database (Denmark)

    Pedersen, Jens Olaf Pepke


    Efter at Solen har øget sin aktivitet gennem 100 år, er der nu tydelige tegn på, at den er ved at falde til ro. Er den ved at gå i dvale? Og vil det i så fald udløse en global kuldeperiode?......Efter at Solen har øget sin aktivitet gennem 100 år, er der nu tydelige tegn på, at den er ved at falde til ro. Er den ved at gå i dvale? Og vil det i så fald udløse en global kuldeperiode?...

  6. Den sproglige leg er super fly

    DEFF Research Database (Denmark)

    Just, Sine Nørholm


    Man kan rappe om alt. I hvert fald hvis man er Marvelous Mosell. I spændingsfeltet mellem fiktion og virkelighed skaber Mosell sin persona i et forjættende 80' er-univers der på en og samme tid er vildt overdrevet og helt autentisk.......Man kan rappe om alt. I hvert fald hvis man er Marvelous Mosell. I spændingsfeltet mellem fiktion og virkelighed skaber Mosell sin persona i et forjættende 80' er-univers der på en og samme tid er vildt overdrevet og helt autentisk....

  7. Magnetic properties of HoCoC2, HoNiC2 and their solid solutions (United States)

    Michor, H.; Steiner, S.; Schumer, A.; Hembara, M.; Levytskyy, V.; Babizhetskyy, V.; Kotur, B.


    Magnetic properties of single crystalline HoCoC2 and the evolution of magnetic and structural features in a series of polycrystalline solid solutions HoCo1-xNixC2 (0 ⩽ x ⩽ 1) are investigated by means of X-ray diffraction, magnetization, magnetic susceptibility and specific heat measurements. The crystal structures of all investigated samples refers to the CeNiC2-type structure (space group Amm 2 and Pearson symbol oS8). Non-isoelectronic substitution of Co by Ni causes a non-linear increase of the unit cell volume and especially a non-monotonous variation of the a and c lattice parameters as well as a pronounced reduction of the C-C bond length of carbon dimers. Temperature dependent magnetization and specific heat measurements reveal a crossover from a ferromagnetic for HoCoC2 with TC = 10.6 (1) K to an antiferromagnetic ground state for HoNiC2 with TN = 2.78 (6) K and a non-monotonous variation of the magnetic ordering temperature with a minimum at intermediate compositions. Crystalline electric field effects of HoCoC2 and HoNiC2 are analysed using combined thermodynamic and magnetic susceptibility data. The electrical resistivity of HoNiC2 displays a distinct anomaly near room temperature which indicates the formation of a charge density wave (CDW) state as earlier reported for several other rare earth nickel dicarbides.

  8. Vidensamfundet - det er sund fornuft

    DEFF Research Database (Denmark)

    Pedersen, Esther Oluffa


    meget kort tid har opnået at blive udmøntet som dansk lov. Sigtet med artiklen er (1) at give en kritisk kommentar til den definition af viden, som ligger til grund for sloganet 'fra tanke til faktura'. Rapporterne analyseres for at belyse den ideologiske baggrund, der ligger bag de strategisk...

  9. N-ov-emb-er

    Indian Academy of Sciences (India)

    " to. Andrew Z Fire - Stanford University School of Medicine Stanford, CA, USA. Craig C Mello - University of Massachusetts Medical School Worcester, MA, USA. -96----------------------------~~--------R-ES-O-N-A-N-C-E--1 -N-ov-e-m-b-er--2-oo-6.

  10. Standardization of (166m)Ho and 243Am/239Np by live-timed anti-coincidence counting with extending dead time. (United States)

    da Silva, C J; Loureiro, J S; Delgado, J U; Poledna, R; Moreira, D S; Iwahara, A; Tauhata, L; da Silva, R L; Lopes, R T


    The National Laboratory for Metrology of Ionizing Radiation (LNMRI)/Brazil acquired (166m)Ho and (243)Am/(239)Np solutions from commercial suppliers in order to realize primary standardization and therefore reducing the associated uncertainties. The method used in the standardization was the live-timed 4πβ(LS)-γ(ΝaI(Tl)) anticoincidence counting. The live-timed anticoincidence system is operated since 2006 in LNMRI and is composed of two MTR2 modules donated by Laboratoire National Henri Becquerel (LNE-LNHB)/France. The data acquisition system uses a homemade LabView program and an Excel file for calculus. These systems have been used for primary standardization at LNMRI for many radionuclides and recently took part in the (124)Sb and (177)Lu International Key Comparisons with good performance. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions

    Directory of Open Access Journals (Sweden)

    Lisanne E. Wisse


    Full Text Available Vanishing white matter (VWM is a leukodystrophy with predominantly early-childhood onset. Affected children display various neurological signs, including ataxia and spasticity, and die early. VWM patients have bi-allelic mutations in any of the five genes encoding the subunits of the eukaryotic translation factor 2B (eIF2B. eIF2B regulates protein synthesis rates under basal and cellular stress conditions. The underlying molecular mechanism of how mutations in eIF2B result in VWM is unknown. Previous studies suggest that brain white matter astrocytes are primarily affected in VWM. We hypothesized that the translation rate of certain astrocytic mRNAs is affected by the mutations, resulting in astrocytic dysfunction. Here we subjected primary astrocyte cultures of wild type (wt and VWM (2b5ho mice to pulsed labeling proteomics based on stable isotope labeling with amino acids in cell culture (SILAC with an L-azidohomoalanine (AHA pulse to select newly synthesized proteins. AHA was incorporated into newly synthesized proteins in wt and 2b5ho astrocytes with similar efficiency, without affecting cell viability. We quantified proteins synthesized in astrocytes of wt and 2b5ho mice. This proteomic profiling identified a total of 80 proteins that were regulated by the eIF2B mutation. We confirmed increased expression of PROS1 in 2b5ho astrocytes and brain. A DAVID enrichment analysis showed that approximately 50% of the eIF2B-regulated proteins used the secretory pathway. A small-scale metabolic screen further highlighted a significant change in the metabolite 6-phospho-gluconate, indicative of an altered flux through the pentose phosphate pathway (PPP. Some of the proteins migrating through the secretory pathway undergo oxidative folding reactions in the endoplasmic reticulum (ER, which produces reactive oxygen species (ROS. The PPP produces NADPH to remove ROS. The proteomic and metabolomics data together suggest a deregulation of ER function in 2b5

  12. High-spin states in sup 166 Lu

    Energy Technology Data Exchange (ETDEWEB)

    Hojman, D.; Kreiner, A.J.; Davidson, M.; Davidson, J.; Debray, M.; Cybulska, E.W.; Pascholati, P.; Seale, W.A. (Departamento de Fisica, Comision Nacional de Energia Atomica, 1429 Buenos Aires, Buenos Aires (Argentina) Departamento de Fisica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires (Argentina) Instituto de Fisica, Universidade de Sao Paulo, Sao Paulo (Brazil))


    High-spin states belonging to {sup 166}Lu have been studied through the {sup 159}Tb({sup 12}C,5{ital n}) fusion-evaporation reaction in the energy range {ital E}({sup 12}C)=75--90 MeV. In-beam and activity singles spectra and {gamma}-{gamma}-{ital t} coincidences have been measured. A completely new level scheme is proposed. Each rotational band is interpreted on the basis of coupling scheme systematics. {ital g}-{ital S} crossing frequencies and alignments have been extracted. {ital B}({ital M}1)/{ital B}({ital E}2) reduced transition probability ratios have been calculated using a semiclassical method and compared to the experimental values.

  13. ER stress and hepatic lipid metabolism

    Directory of Open Access Journals (Sweden)

    Huiping eZhou


    Full Text Available The endoplasmic reticulum (ER is an important player in regulating protein synthesis and lipid metabolism. Perturbation of ER homeostasis, referred as ER stress, has been linked to numerous pathological conditions, such as inflammation, cardiovascular diseases and metabolic disorders. The liver plays a central role in regulating nutrient and lipid metabolism. Accumulating evidence implicates that ER stress disrupts lipid metabolism and induces hepatic lipotoxicity. Here, we review the major ER stress signaling pathways, how ER stress contributes to the dysregulation of hepatic lipid metabolism, and the potential causative mechanisms of ER stress in hepatic lipotoxicity. Understanding the role of ER stress in hepatic metabolism may lead to the identification of new therapeutic targets for metabolic diseases.

  14. Endoplasmic Reticulum (ER) Stress and Endocrine Disorders. (United States)

    Ariyasu, Daisuke; Yoshida, Hiderou; Hasegawa, Yukihiro


    The endoplasmic reticulum (ER) is the organelle where secretory and membrane proteins are synthesized and folded. Unfolded proteins that are retained within the ER can cause ER stress. Eukaryotic cells have a defense system called the "unfolded protein response" (UPR), which protects cells from ER stress. Cells undergo apoptosis when ER stress exceeds the capacity of the UPR, which has been revealed to cause human diseases. Although neurodegenerative diseases are well-known ER stress-related diseases, it has been discovered that endocrine diseases are also related to ER stress. In this review, we focus on ER stress-related human endocrine disorders. In addition to diabetes mellitus, which is well characterized, several relatively rare genetic disorders such as familial neurohypophyseal diabetes insipidus (FNDI), Wolfram syndrome, and isolated growth hormone deficiency type II (IGHD2) are discussed in this article.

  15. Endoplasmic Reticulum (ER Stress and Endocrine Disorders

    Directory of Open Access Journals (Sweden)

    Daisuke Ariyasu


    Full Text Available The endoplasmic reticulum (ER is the organelle where secretory and membrane proteins are synthesized and folded. Unfolded proteins that are retained within the ER can cause ER stress. Eukaryotic cells have a defense system called the “unfolded protein response” (UPR, which protects cells from ER stress. Cells undergo apoptosis when ER stress exceeds the capacity of the UPR, which has been revealed to cause human diseases. Although neurodegenerative diseases are well-known ER stress-related diseases, it has been discovered that endocrine diseases are also related to ER stress. In this review, we focus on ER stress-related human endocrine disorders. In addition to diabetes mellitus, which is well characterized, several relatively rare genetic disorders such as familial neurohypophyseal diabetes insipidus (FNDI, Wolfram syndrome, and isolated growth hormone deficiency type II (IGHD2 are discussed in this article.

  16. PODAAC-ERS13-IMWF0 (United States)

    National Aeronautics and Space Administration — The European Remote Sensing Satellite generation 2 (ERS-2) Level 3 Mean Wind Fields dataset is derived from the ERS-2 scatterometer data and is produced and...

  17. Holmium laser lithotripsy (HoLL) of ureteral calculi (United States)

    Kuntz, Rainer M.; Lehrich, Karin; Fayad, Amr


    The effectiveness and side effects of ureteroscopic HoLL of ureteral stones should be evaluated. In 63 patients (17 female, 46 males) a total of 75 stones of 3-20 mm diameter were treated with ureteroscopic HoLL. 18.7 percent of stones were located in the proximal third, 24.0 percent in the middle third and 57.3 percent in the distal third of the ureter. HoLL was performed with small diameter semirigid and flexible ureteroscopes, 220 or 365 nm flexible laser fibers and a holmium:YAG laser at a power of 5-15 W (0.5-1.0 J, 10- 15 Hz). 47 of 63 patients (74.6 percent) were immediately free of stones, and 8 others (12.6 percent) lost their residual fragments spontaneously within two weeks. Another 2 patients received additional chmolitholysis for uric acid stone fragments, i.e. 90.5 percent of patients were stone free by one sitting of ureterscopic HoLL. Of the remaining 6 patients (9.5 percent) who still had residual calculi 4 weeks after HoLL, 2 asymptomatic patients refused any additional treatment, 2 patients preferred treatment with ESWL, and 2 patients had a successful second HoLL, thereby raising the success rate of ureteroscopic HoLL to 93.7 percent. 2 patients showed contrast medium extravasation on retrograde ureterograms, due to guide wire perforation. No ureteral stricture occurred. In conclusion, transurethral ureteroscopic HoLL proved to be a safe and successful minimal invasive treatment of ureteral calculi.

  18. Er det naturlige altid godt og rigtigt?

    DEFF Research Database (Denmark)

    Gjerris, Mickey


    Beder man mennesker lukke øjnene og se ’naturen’ for sig, ender de fleste med at se bjerge, dale, vand, planter, dyr og himmel. Det, der som oftest ikke er til stede, er dem selv – mennesket.......Beder man mennesker lukke øjnene og se ’naturen’ for sig, ender de fleste med at se bjerge, dale, vand, planter, dyr og himmel. Det, der som oftest ikke er til stede, er dem selv – mennesket....

  19. Co-precipitation synthesis of lutetium aluminum garnet (LuAG) powders: The influence of ethanol (United States)

    Pan, Liangjie; Jiang, Benxue; Fan, Jintai; Zhang, Pande; Mao, Xiaojian; Zhang, Long


    Aluminum Garnet (LuAG) precursors were co-precipitated by using ethanol-water as the precipitant solvent. The effect of different volume ratios of ethanol to water (R) on the preparation of pure-phase LuAG powders has been mainly studied. The evolution of phase, composition and micro-structure of the as-synthesized LuAG powders were characterized by TG/DTA, FTIR, XRD, BET, and SEM. The BET-equivalent diameter of LuAG nano particles increased with R. The ethanol-water solvent does not change the main composition of the LuAG precursors, but has great influence on the morphology of the final LuAG nano particles. Uniformly dispersed LuAG powders calcined at 1200 °C for 3 h with a particle size of approximately 120 nm were obtained by using ethanol-water solvent with proper R = 1. The mechanism of ethanol in the preparation process was discussed.

  20. Optimization of metallic magnetic calorimeters with embedded {sup 163}Ho

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, C.; Enss, C.; Fleischmann, A.; Gastaldo, L.; Hassel, C.; Hengstler, D.; Haehnle, S.; Kempf, S.; Krantz, M.; Wegner, M. [Kirchhoff-Institut fuer Physik, Heidelberg (Germany); Dorrer, H.; Duellmann, C.E.; Eberhardt, K.; Kieck, T.; Schneider, F.; Wendt, K. [Johannes Gutenberg-Universitaet, Mainz (Germany); Johnston, K. [Physics Department CERN, Geneva (Switzerland); Koester, U. [Institut Laue-Langevin, Grenoble (France); Tuerler, A. [Laboratory of Radiochemistry and Environmental Chemistry, Paul Scherrer Institut, Villigen (Switzerland)


    The Electron Capture in {sup 163}Ho (ECHo) collaboration plans to reach sub-eV sensitivity on the electron neutrino mass by the analysis of high statistics of {sup 163}Ho electron capture spectra. Large arrays of metallic magnetic calorimeters (MMCs) with enclosed {sup 163}Ho read out using microwave SQUID multiplexing will be used for the measurement of the spectrum. With first prototypes of MMCs having the {sup 163}Ho source ion-implanted in the absorbers, operated at 25 mK, an energy resolution ΔE{sub FWHM}=7.6 eV and a signal rise time τ=130 ns have been achieved, paving the way to the first stage of the experiment (ECHo 1k). We present the optimization of MMCs and of the methods to embed the high purity {sup 163}Ho source in detector absorbers. In particular we discuss how to define the optimal activity per pixel considering the limits coming from the allowed unresolved pileup fraction and from the additional contribution of detector heat capacity related to the magnetic moments of {sup 163}Ho.

  1. Optical properties of Ho3+ ions in lead phosphate glasses (United States)

    Srinivasa Rao, Ch.; Upendra Kumar, K.; Babu, P.; Jayasankar, C. K.


    Ho3+-doped lead phosphate (P2O5 + K2O + Al2O3 + PbO + Na2O + Ho2O3) glasses have been prepared by conventional melt quenching technique. The optical properties have been characterized through absorption, emission and gain spectra and decay rate analysis. A strong dependence of the Ω2 parameter on the hypersensitive transition has been noticed. Using the Judd-Ofelt intensity parameters, various radiative properties like transition probabilities, branching ratios and radiative lifetimes for various emission levels has been evaluated. The radiative lifetime for the 5S2(5F4) fluorescent level and peak stimulated emission cross-section for the 5S2(5F4) → 5I8 transition are found to be 330 μs and 1.43 × 10-20 cm2, respectively. Using the McCumber theory, absorption and emission cross-sections for the 5I7 → 5I8 transition (˜2.0 μm) of the Ho3+ ion have been obtained and gain spectra are also computed as a function of population inversion. The peak stimulated emission cross-section and gain coefficient for Ho3+-doped lead phosphate glasses have been compared with other reported Ho3+:systems. The analysis indicates that these Ho3+:glasses exhibit relatively better properties for application in mid-infrared lasers at a wavelength of about 2.0 μm.

  2. A novel Lu{sup 3+} fluorescent nano-chemosensor using new functionalized mesoporous structures

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, Morteza, E-mail: [Department of Life Science Engineering, Faculty of New Sciences and Technologies, University of Tehran, Tehran (Iran, Islamic Republic of); Ganjali, Mohammad Reza; Rafiei-Sarmazdeh, Zahra; Faridbod, Farnoush [Center of Excellence in Electrochemistry, Faculty of Chemistry, University of Tehran, Tehran (Iran, Islamic Republic of); Goldooz, Hassan; Badiei, Alireza [School of Chemistry, University College of Science, University of Tehran, Tehran (Iran, Islamic Republic of); Nourozi, Parviz [Center of Excellence in Electrochemistry, Faculty of Chemistry, University of Tehran, Tehran (Iran, Islamic Republic of); Mohammadi Ziarani, Ghodsi [Department of Chemistry, Faculty of Science, Alzahra University, Tehran (Iran, Islamic Republic of)


    Graphical abstract: A novel Lu{sup 3+} sensitive fluorescent chemosensor is constructed through the preparation of 8-hydroxyquinoline functionalized mesoporous silica with ordered hexagonal array structure (LUS-SPS-Q). Fluorescence measurements revealed that the emission intensity of the Lu{sup 3+}-bound mesoporous material increases significantly upon addition of various concentrations of Lu{sup 3+}, while the mono-, di-, trivalent cations result in either unchanged or weakened intensities. Highlights: ► 8-Hydroxyquinoline functionalized mesoporous silica is introduced as a selective fluorescent probe for lutetium ions. ► Fluorescent intensity of the chemical probe enhances upon binding to lutetium ions. ► Fluorescence measurements were done in a suspension of mesoporous silica in aqueous solution. -- Abstract: A new Lu{sup 3+} sensitive fluorescent chemosensor is designed using 8-hydroxyquinoline functionalized mesoporous silica with highly ordered structure (LUS-SPS-Q). The characterization of LUS-SPS-Q showed that the organized structure has been preserved after the post grafting procedure. The synthesized material showed a selective interaction with Lu{sup 3+} ion, most probably due to the presence of the fluorophore moiety at its surface. The emission intensity of the Lu{sup 3+}-bound mesoporous material increases with an increase in concentrations of Lu{sup 3+} ion. Addition of other mono-, di-, trivalent ions resulted in insignificant change in the fluorescent intensity. The enhancement of fluorescence is attributed to the strong covalent binding of Lu{sup 3+} ion. The linear response range of Lu{sup 3+} chemo-sensor was from 1.6 × 10{sup −7} to 1.0 × 10{sup −5} mol L{sup −1}. The Limit of detection obtained was 8.2 × 10{sup −8} mol L{sup −1} and the pH range which the proposed chemo-sensor can be applied was 3.3–8.3.

  3. Kronik: Diskussion om timetal er oldnordisk

    DEFF Research Database (Denmark)

    Koefoed Hansen, Lone


    Det er ikke antallet af timer med mig, underviseren, der afgør, hvor meget en studerende lærer. Det afgørende er derimod, hvad jeg formår at anspore de studerende til at lære, mens de ikke er i samme lokale som mig, skriver kronikøren....

  4. Hvorfor er sygeplejersker usynlige i offentlige medier?

    DEFF Research Database (Denmark)

    Joensen, Annemi Lund; Hall, Elisabeth


    Når der er sygeplejerelevante emner til debat i de offentlige medier på Færøerne, bærer debatten præg af sygeplejerskers manglende deltagelse. Sygeplejerskerne er usynlige. Et eksempel på dette er en debat om besparelser inden for ældreomsorgen. Til trods for at besparelsen fik omfattende konsekv...

  5. Delayed crossing in the {pi}h{sub 9/2} 1/2{sup -}[541] band of {sup 173}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Venkova, T. [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Institute of Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, BG-1784, Sofia (Bulgaria); Lieder, R.M.; Gast, W.; Podsvirova, E.; Jaeger, H.M.; Mihailescu, L. [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Bazzacco, D.; Menegazzo, R.; Lunardi, S.; Alvarez, C. Rossi; Ur, C.; Martinez, T.; Axiotis, M. [Istituto Nazionale di Fisica Nucleare, Dipartimento di Fisica dell' Universita, Sezione di Padova, I-35131, Padova (Italy); Angelis, G. de; Napoli, D. [Laboratori Nazionali di Legnaro, Istituto Nazionale di Fisica Nucleare, I-35020, Legnaro (Italy); Urban, W.; Rzaca-Urban, T. [Institute of Experimental Physics, University of Warsaw, PL-00-681, Warszawa (Poland)


    High-spin states in the odd-proton nucleus {sup 173}Lu have been populated in a {sup 170}Er({sup 7}Li,4n) reaction and the emitted {gamma}-radiation was detected with the GASP array. The favoured and unfavoured sequences of the {pi}1/2{sup -}[541] band have been considerably extended. The favoured sequence does not show any indication of a band crossing up to a rotational frequency of {approx} 0.45 MeV. This is the largest crossing frequency ever observed for 1/2{sup -} [541] bands of odd-proton nuclei with 67{<=}Z{<=}77 and 90{<=}N{<=}106. Previous Cranked Shell Model (CSM) calculations underestimate the crossing frequency by 100 keV. (orig.)

  6. Redefinícia mólu – pozadie zmien v SI sústave a ich vplyv na vzdelávanie

    Directory of Open Access Journals (Sweden)

    Romana Schubertová


    Full Text Available Predkladaný príspevok prepája aktuálnu diskusiu o redefinícii základných jednotiek SI sústavy s vyučovaním chémie. Plánovaná definícia mólu má byť založená na presnom stanovení Avogadrovej konštanty. Problémy, ktoré sú spojené s takýmto definovaním mólu, vychádzajú však aj zo samotnej histórie veličiny látkové množstvo. Jedným zo základných problémov tohto charakteru je, že látkové množstvo je spomedzi základných veličín jedinou diskontinuálnou veličinou, ktorej jednotka mól nebola zavedená na základe vlastností prírody, ale na základe ľudskej dohody. Je teda otázne či je mól zaradený medzi základné jednotky SI sústavy logicky správne. Aj z tohto dôvodu je veličina látkové množstvo zaujímavá taktiež z didaktického hľadiska, ktoré je v príspevku diskutované.

  7. Peroxisomes: offshoots of the ER. (United States)

    van der Zand, Adabella; Tabak, Henk F


    Peroxisomes are part of the ubiquitous set of eukaryotic organelles. They are small, single membrane bounded vesicles, specialized in the degradation of very-long-chain fatty acids and in synthesis of myelin lipids. Once considered inconspicuous, recent new insights in the formation and function of peroxisomes have revealed a much more subtle interplay between organelles that warrant a re-evaluation of the historical assignment of peroxisomes as being either autonomous or ER-derived. Peroxisomes acquire their lipids and membrane proteins from the ER, whereas they import their matrix proteins directly from the cytosol. Remarkably, many of its metabolic enzymes and factors controlling peroxisome abundance (fission and inheritance) too are shared with other organelles, stressing interdependence among cellular compartments. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. [{sup 177}Lu]DOTA-anti-CD20: Labeling and pre-clinical studies

    Energy Technology Data Exchange (ETDEWEB)

    Audicio, Paola F., E-mail: [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Castellano, Gustavo, E-mail: [FaMAF, Universidad Nacional de Cordoba, Ciudad Universitaria, 5016 Cordoba (Argentina); Tassano, Marcos R.; Rezzano, Maria E.; Fernandez, Marcelo [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay); Riva, Eloisa [Clinica Hematologica ' Prof. Dra. L. Diaz' , Hospital de Clinicas. Av. Italia. sn, Montevideo (Uruguay); Robles, Ana; Cabral, Pablo; Balter, Henia; Oliver, Patricia [Departamento de Radiofarmacia, Centro de Investigaciones Nucleares, Facultad de Ciencias, Universidad de la Republica, Mataojo 2055, 11400 Montevideo (Uruguay)


    Anti-CD20 (Rituximab), a specific chimeric monoclonal antibody used in CD20-positive Non-Hodgkin's Lymphoma, was conjugated to a bifunctional quelate (DOTA) and radiolabeled with {sup 177}Lu through a simple method. [{sup 177}Lu]-DOTA-anti-CD20 was obtained with a radiochemical purity higher than 97%, and showed good chemical and biological stability, maintaining its biospecificity to CD20 antigens. Monte Carlo simulation showed high doses deposited on a spheroid tumor mass model. This method seems to be an appropriate alternative for the production of [{sup 177}Lu]-DOTA-anti-CD20 as therapeutic radiopharmaceutical.

  9. Results of individual patient dosimetry in peptide receptor radionuclide therapy with 177Lu DOTA-TATE and 177Lu DOTA-NOC. (United States)

    Wehrmann, Christiane; Senftleben, Stefan; Zachert, Carolin; Müller, Dirk; Baum, Richard P


    One of the few treatment options for inoperable neuroendocrine tumors (NET) is peptide receptor radiotherapy with somatostatin analogs. In this study, we compared the dosimetric parameter uptake, half-life (kinetics), and mean absorbed organ and tumor doses of (177)Lu DOTA-NOC and (177)Lu DOTA-TATE. Ninety-five (95) post-therapeutic dosimetric assessments using (177)Lu DOTA-TATE and 8 using (177)Lu DOTA-NOC in 69 patients with neuroendocrine tumors with high somatostatin receptor expression (verified by Ga-68 DOTA-NOC positron emission tomography/computed tomography) were analyzed. Dosimetric calculations were performed according to the Medical Internal Radiation Dose scheme. (177)Lu DOTA-NOC showed a significantly (p NOC, as compared to 0.05 mGy/MBq for DOTA-TATE. Renal and spleen uptake and radiation doses were not significantly higher for DOTA-NOC. The uptake in tumor lesions and the mean absorbed tumor dose were higher for DOTA-TATE. The red marrow dose was approximately 0.2 Gy. Our first results demonstrated that the higher in vitro affinity of DOTA-NOC leads to a higher uptake in normal tissues and, therefore, to an increase in the whole-body dose. The high interpatient variability of these results makes an individual patient dosimetry obligatory.

  10. Minimising Immunohistochemical False Negative ER Classification Using a Complementary 23 Gene Expression Signature of ER Status

    DEFF Research Database (Denmark)

    Li, Qiyuan; Eklund, Aron Charles; Birkbak, Nicolai Juul


    BACKGROUND: Expression of the oestrogen receptor (ER) in breast cancer predicts benefit from endocrine therapy. Minimising the frequency of false negative ER status classification is essential to identify all patients with ER positive breast cancers who should be offered endocrine therapies...... subtypes as compared to IHC-based determination has not been systematically evaluated. Here we attempt to reduce the frequency of false negative ER status classification using two gene expression approaches and compare these methods to IHC based ER status in terms of predictive and prognostic concordance....../SIGNIFICANCE: Expression-based ER status classification may complement IHC to minimise false negative ER status classification and optimise patient stratification for endocrine therapies....

  11. Výložník kombinovaného skládkového stroje


    Štursa, Martin


    Tato diplomová práce se zabývá konstrukcí částí kombinovaného skládkového stroje určeného pro obsluhu skládky hnědého uhlí u uhelné elektrárny. Nejprve jsou nadefinovány základní parametry stroje a silové účinky zatěžující stroj během provozu. Práce dále obsahuje návrh ocelové konstrukce kolesového výložníku, kolesa, korečků, pohonu kolesa, hřídele, ložisek a dalších částí kolesového výložníku. Tyto součásti jsou ověřeny analytickými nebo konečnoprvkovými výpočty. This master’s thesis deal...

  12. Reaction of HO2 with O3 and the effect of water vapor on HO2 kinetics (United States)

    Demore, W. B.


    The effects of temperature and water vapor concentration on the ratio of the rate constant of the reaction HO2 + O3 yields OH + 2(O2) to the square root of the rate constant for the reaction HO2 + HO2 yields H2O2 + O2 are determined. Photolysis of H2-O2-O3 mixtures at 253.7 nm was carried out with H2O pressures in the range 0 to 15 torr at a temperature range of -42.5 to 61 C along with 184.9 nm photolysis of H2O-O2-O3 mixtures. It is shown that the rate of O3 photolysis is suppressed by the addition of water vapor and it is suggested that this effect is realized in the HO2 + HO2 yields H2O2 + O2 reaction. The calculated expression for the temperature dependence of the rate constant ratio is found to be in good agreement with that calculated from separate rate constants. Rate constants determined for the reaction OH + HO2 yields H2O + O2 are found to be higher than those previously determined, presumably due to increased pressure, indicating that atmospheric models should take into account the possible pressure dependences of the reactions considered.

  13. São Luís, capitale du Maranhão, capitale rêvée de la France équinoxiale: the dream capital of equinoctial France

    Directory of Open Access Journals (Sweden)

    Guy Martinière


    Full Text Available La ville de São Luís do Maranhão a été inscrite par l'UNESCO sur la liste du Patrimoine mondial de l'Humanité en décembre 1997 en raison de la qualité de l'architecture et de l'urbanisme des XVIIIème et XIXème siècles de son Centre historique. Toutefois, avant de devenir une ville portugaise des Tropiques, São Luís avait été fondée par les Français commandés par La Ravardière dès 1612. Elle fut alors, pendant trois ans, la "capitale rêvée" d'une utopie, celle de la monarchie française du roi Louis XIII. Cette monarchie n'aspirait-elle pas à créer, en Amérique du Sud, sur les côtes du Brésil, un empire outre-mer, la "France équinoxiale", comme la ville de Québec, fondée par Champlain, était devenue la capitale de la "Nouvelle France" en Amérique du Nord ? La ville de São Luís revendique aujourd'hui cet héritage et ambitionne de devenir un "carrefour des cultures" du monde.

  14. Tank 241-ER-311, grab samples, ER311-98-1, ER311-98-2, ER311-98-3 analytical results for the final report

    Energy Technology Data Exchange (ETDEWEB)

    FULLER, R.K.


    This document is the final report for catch tank 241-ER-311 grab samples. Three grab samples ER311-98-1, ER311-98-2 and ER311-98-3 were taken from East riser of tank 241-ER-311 on August 4, 1998 and received by the 222-S Laboratory on August 4, 1998. Analyses were performed in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1998)and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Mulkey and Miller, 1997). The analytical results are presented in the data summary report (Table 1). No notification limits were exceeded.

  15. Langston University - High Energy Physics (LU-HEP)

    Energy Technology Data Exchange (ETDEWEB)

    Snow, Dr., Joel [Langston Univ., OK (United States)


    This final report is presented by Langston University (LU) for the project entitled "Langston University High Energy Physics" (LUHEP) under the direction of principal investigator (PI) and project director Professor Joel Snow. The project encompassed high energy physics research performed at hadron colliders. The PI is a collaborator on the DZero experiment at Fermi National Accelerator Laboratory in Batavia, IL, USA and the ATLAS experiment at CERN in Geneva, Switzerland and was during the entire project period from April 1, 1999 until May 14, 2012. Both experiments seek to understand the fundamental constituents of the physical universe and the forces that govern their interactions. In 1999 as member of the Online Systems group for Run 2 the PI developed a cross-platform Python-based, Graphical User Interface (GUI) application for monitoring and control of EPICS based devices for control room use. This served as a model for other developers to enhance and build on for further monitoring and control tasks written in Python. Subsequently the PI created and developed a cross-platform C++ GUI utilizing a networked client-server paradigm and based on ROOT, the object oriented analysis framework from CERN. The GUI served as a user interface to the Examine tasks running in the D\\O\\ control room which monitored the status and integrity of data taking for Run 2. The PI developed the histogram server/control interface to the GUI client for the EXAMINE processes. The histogram server was built from the ROOT framework and was integrated into the D\\O\\ framework used for online monitoring programs and offline analysis. The PI developed the first implementation of displaying histograms dynamically generated by ROOT in a Web Browser. The PI's work resulted in several talks and papers at international conferences and workshops. The PI established computing software infrastructure at LU and U. Oklahoma (OU) to do analysis of DZero production data and produce simulation

  16. Mitochondria-Associated Membranes and ER Stress. (United States)

    van Vliet, Alexander R; Agostinis, Patrizia


    The endoplasmic reticulum (ER) is a crucial organelle for coordinating cellular Ca(2+) signaling and protein synthesis and folding. Moreover, the dynamic and complex membranous structures constituting the ER allow the formation of contact sites with other organelles and structures, including among others the mitochondria and the plasma membrane (PM). The contact sites that the ER form with mitochondria is a hot topic in research, and the nature of the so-called mitochondria-associated membranes (MAMs) is continuously evolving. The MAMs consist of a proteinaceous tether that physically connects the ER with mitochondria. The MAMs harness the main functions of both organelles to form a specialized subcompartment at the interface of the ER and mitochondria. Under homeostatic conditions, MAMs are crucial for the efficient transfer of Ca(2+) from the ER to mitochondria, and for proper mitochondria bioenergetics and lipid synthesis. MAMs are also believed to be the master regulators of mitochondrial shape and motility, and to form a crucial site for autophagosome assembly. Not surprisingly, MAMs have been shown to be a hot spot for the transfer of stress signals from the ER to mitochondria, most notably under the conditions of loss of ER proteostasis, by engaging the unfolded protein response (UPR). In this chapter after an introduction on ER biology and ER stress, we will review the emerging and key signaling roles of the MAMs, which have a root in cellular processes and signaling cascades coordinated by the ER.

  17. The electronic structure and optical properties of Lu-doped ZnO nanotubes (United States)

    Wu, Y.; Zheng, S. K.


    The electronic band structures, density of states, and optical properities of pure and Lu-doped zigzag single-walled (6, 0) ZnO nanotubes (SWZONT) were studied using the density functional method whithin generalized gradient approximation. For the pure SWZONT system, the Fermi level locates at the valence band maxmum, while it deviates to the conduction band, and exhibits metal-like charicteristics after the Lu atom is introduced into the system. The Lu-doped SWZONT system is stable, and the semiconductor type (N type) is enhanced. Additionally, the catalytic oxidation activity was improved. The optical properties indicate that the Lu-doped SWZONT materials can be applied to UV optoelectronic devices.

  18. Intrinsic magnetic properties of hexagonal LuFeO3 and the effects of nonstoichiometry

    Directory of Open Access Journals (Sweden)

    Jarrett A. Moyer


    Full Text Available We used oxide molecular-beam epitaxy in a composition-spread geometry to deposit hexagonal LuFeO3 (h-LuFeO3 thin films with a monotonic variation in the Lu/Fe cation ratio, creating a mosaic of samples that ranged from iron rich to lutetium rich. We characterized the effects of composition variation with x-ray diffraction, atomic force microscopy, scanning transmission electron microscopy, and superconducting quantum interference device magnetometry. After identifying growth conditions leading to stoichiometric film growth, an additional sample was grown with a rotating sample stage. From this stoichiometric sample, we determined stoichiometric h-LuFeO3 to have a TN = 147 K and Ms = 0.018 μB/Fe.

  19. lu ja liikumine kui ruumipraktikad = Memory and motion as spatial practices / Morten Lund

    Index Scriptorium Estoniae

    Lund, Morten, 1972-


    Artiklis on käsitletud nelja uurimust ruumist, mis illustreerivad võimalusi, kuidas sisearhitektuur võib kaasata mälu ja liikumise kui ruumilised praktikad läbi ruumilise kunsti ning 1:1 eksperimentide

  20. Scintillation properties of Sc-, Pr-, and Ce-doped LuAG epitaxial garnet films (United States)

    Prusa, P.; Kucera, M.; Mares, J. A.; Nikl, M.; Nitsch, K.; Hanus, M.; Onderisinova, Z.; Cechak, T.


    Lu3Al5O12 (LuAG) films were grown from the BaO-B2O3-BaF2 flux on LuAG and YAG substrates using the liquid phase epitaxy method (LPE). They were doped with Pr3+, Sc3+, and eventually still with Ce3+ ions. Photoelectron yield, its time dependence, and energy resolution were measured under α-particle excitation. A sample of the Czochralski-grown bulk LuAG:Pr single crystal was measured as a reference. The best performing epitaxial films had low Sc3+ concentration and appeared comparable or superior to the Czochralski-grown crystal in terms of photoelectron yield and relative intensity of the fast component of scintillation response. High concentration of Sc3+ ions results in slowdown of response and lower photoelectron yield. Some samples with lower photoelectron yield than that of the Czochralski-grown crystal did exhibit better energy resolution.

  1. Gamma radiation exposure of accompanying persons due to Lu-177 patients

    Directory of Open Access Journals (Sweden)

    Kovan Bilal


    Full Text Available Neuroendocrine tumours (NET are cancers usually observed and arisen in the stomach, intestine, pancreas and breathing system. Recently, radionuclide therapy applications with Lu-177 peptide compound are rapidly growing; especially effective clinical results are obtained in the treatment of well-differentiated and metastatic NET. In this treatment, Lu-177-DOTA, a beta emitter radioisotope in the radiopharmaceutical form, is given to the patient by intravenous way. Lu-177 has also gamma rays apart from beta rays. Gamma rays have 175 keV average energy and these gamma rays should be under the control in terms of radiation protection. In this study, we measured the exposure dose from the Lu-177 patient.

  2. Magnetic state controllable critical temperature in epitaxial Ho/Nb bilayers

    Directory of Open Access Journals (Sweden)

    Yuanzhou Gu


    Full Text Available We study the magnetic properties of Ho thin films with different crystallinity (either epitaxial or non-epitaxial and investigate their proximity effects with Nb thin films. Magnetic measurements show that epitaxial Ho has large anisotropy in two different crystal directions in contrast to non-epitaxial Ho. Transport measurements show that the superconducting transition temperature (Tc of Nb thin films can be significantly suppressed at zero field by epitaxial Ho compared with non-epitaxial Ho. We also demonstrate a direct control over Tc by changing the magnetic states of the epitaxial Ho layer, and attribute the strong proximity effects to exchange interaction.

  3. Multimodal Somatostatin Receptor Theranostics Using [(64)Cu]Cu-/[(177)Lu]Lu-DOTA-(Tyr(3))octreotate and AN-238 in a Mouse Pheochromocytoma Model. (United States)

    Ullrich, Martin; Bergmann, Ralf; Peitzsch, Mirko; Zenker, Erik F; Cartellieri, Marc; Bachmann, Michael; Ehrhart-Bornstein, Monika; Block, Norman L; Schally, Andrew V; Eisenhofer, Graeme; Bornstein, Stefan R; Pietzsch, Jens; Ziegler, Christian G


    Pheochromocytomas and extra-adrenal paragangliomas (PHEO/PGLs) are rare catecholamine-producing chromaffin cell tumors. For metastatic disease, no effective therapy is available. Overexpression of somatostatin type 2 receptors (SSTR2) in PHEO/PGLs promotes interest in applying therapies using somatostatin analogs linked to radionuclides and/or cytotoxic compounds, such as [(177)Lu]Lu-DOTA-(Tyr(3))octreotate (DOTATATE) and AN-238. Systematic evaluation of such therapies for the treatment of PHEO/PGLs requires sophisticated animal models. In this study, the mouse pheochromocytoma (MPC)-mCherry allograft model showed high tumor densities of murine SSTR2 (mSSTR2) and high tumor uptake of [(64)Cu]Cu-DOTATATE. Using tumor sections, we assessed mSSTR2-specific binding of DOTATATE, AN-238, and somatostatin-14. Therapeutic studies showed substantial reduction of tumor growth and tumor-related renal monoamine excretion in tumor-bearing mice after treatment with [(177)Lu]Lu-DOTATATE compared to AN-238 and doxorubicin. Analyses did not show agonist-dependent receptor downregulation after single mSSTR2-targeting therapies. This study demonstrates that the MPC-mCherry model is a uniquely powerful tool for the preclinical evaluation of SSTR2-targeting theranostic applications in vivo. Our findings highlight the therapeutic potential of somatostatin analogs, especially of [(177)Lu]Lu-DOTATATE, for the treatment of metastatic PHEO/PGLs. Repeated treatment cycles, fractionated combinations of SSTR2-targeting radionuclide and cytotoxic therapies, and other adjuvant compounds addressing additional mechanisms may further enhance therapeutic outcome.

  4. The impact of repeated cycles of radioligand therapy using [177Lu]Lu-PSMA-617 on renal function in patients with hormone refractory metastatic prostate cancer. (United States)

    Yordanova, Anna; Becker, Anja; Eppard, Elisabeth; Kürpig, Stefan; Fisang, Christian; Feldmann, Georg; Essler, Markus; Ahmadzadehfar, Hojjat


    [177Lu]Lu-PSMA-617 is a well-tolerated therapy for the treatment of metastatic prostate cancer. However, because of the mainly renal excretion of the tracer, the kidneys are one of the most limiting organs. The purpose of this study was to examine the post-therapeutic changes in renal function over time and to identify risk factors for developing renal toxicity. We also tested the reliability of markers for renal function monitoring. Fifty-five patients with castrate-resistant metastatic prostate cancer treated with at least three cycles of [177Lu]Lu-PSMA-617 were investigated. Renal function was assessed through laboratory tests (creatinine, GFR, cystatin C) and Tc-99 m-MAG3 measurements. Adverse events were classified according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0. To identify risk factors for renal toxicity, we used Pearson's correlation coefficient and the corresponding p values. None of the 55 patients experienced severe nephrotoxicity (grade 3/4). In 14 patients (25%), we observed increased creatinine levels of CTC 1° or 2°. There were 16 cases of increased GFR (grade 1/2). At the baseline, only 14 patients had elevated cystatin C. However, post-therapeutic cystatin C was elevated in 32 patients (58%). A significant effect on renal function was found for age (p = 0.049), hypertension (p = 0.001) and pre-existing kidney disease (p = 0.001). The most reliable predictive markers of nephrotoxicity were TER-MAG3 and cystatin C. Renal toxicity in patients treated with [177Lu]Lu-PSMA-617 was low. There was no (sub)acute grade 3 or 4 nephrotoxicity.

  5. The impact of repeated cycles of radioligand therapy using [{sup 177}Lu]Lu-PSMA-617 on renal function in patients with hormone refractory metastatic prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Yordanova, Anna; Becker, Anja; Eppard, Elisabeth; Kuerpig, Stefan; Essler, Markus; Ahmadzadehfar, Hojjat [University Hospital Bonn, Department of Nuclear Medicine, Bonn (Germany); Fisang, Christian [University Hospital Bonn, Department of Urology, Bonn (Germany); Feldmann, Georg [University Hospital Bonn, Department of Internal Medicine, MED3, Bonn (Germany)


    [{sup 177}Lu]Lu-PSMA-617 is a well-tolerated therapy for the treatment of metastatic prostate cancer. However, because of the mainly renal excretion of the tracer, the kidneys are one of the most limiting organs. The purpose of this study was to examine the post-therapeutic changes in renal function over time and to identify risk factors for developing renal toxicity. We also tested the reliability of markers for renal function monitoring. Fifty-five patients with castrate-resistant metastatic prostate cancer treated with at least three cycles of [{sup 177}Lu]Lu-PSMA-617 were investigated. Renal function was assessed through laboratory tests (creatinine, GFR, cystatin C) and Tc-99 m-MAG3 measurements. Adverse events were classified according to the Common Terminology Criteria for Adverse Events (CTCAE) v4.0. To identify risk factors for renal toxicity, we used Pearson's correlation coefficient and the corresponding p values. None of the 55 patients experienced severe nephrotoxicity (grade 3/4). In 14 patients (25%), we observed increased creatinine levels of CTC 1 or 2 . There were 16 cases of increased GFR (grade 1/2). At the baseline, only 14 patients had elevated cystatin C. However, post-therapeutic cystatin C was elevated in 32 patients (58%). A significant effect on renal function was found for age (p = 0.049), hypertension (p = 0.001) and pre-existing kidney disease (p = 0.001). The most reliable predictive markers of nephrotoxicity were TER-MAG3 and cystatin C. Renal toxicity in patients treated with [{sup 177}Lu]Lu-PSMA-617 was low. There was no (sub)acute grade 3 or 4 nephrotoxicity. (orig.)

  6. The sensitivity of laser induced fluorescence instruments at low pressure to RO2 radicals and the use of this detection method to determine the yield of HO2 during OH-initiated isoprene oxidation (United States)

    Heard, D. E.; Whalley, L. K.; Blitz, M. A.; Seakins, P. W.


    a dry air flow at variable positions along the flow-tube; Isoprene was added downstream of the lamp. Theoretical studies (Peeters et al., 2009) suggest an HO2 yield of 0.7 on a time-scale of a few seconds. Results from the recent laboratory studies will be discussed. Fuchs, H., Bohn, B., Hofzumahaus, A., Holland, F., Lu, K., Nehr, S., Rohrer, F., and Wahner, A.: Detection of HO2 by laser-induced fluorescence: Calibration and interferences from RO2 radicals, Atmos Meas Tech Discuss, 4, 1255-1302, 2011. Heard, D. E., and Pilling, M. J.: Measurement of OH and HO2 in the troposphere, Chem Rev, 103, 5163-5198, 2003. Peeters, J., Nguyen, T. L., and Vereecken, L.: HOx radical regeneration in the oxidation of isoprene, Phys Chem Chem Phys, 11, 5935-5939, 2009.

  7. Theoretical characterization of the potential energy surface for H + O2 yields HO2(asterisk) yields HO + O. II - The potential for H atom exchange in HO2 (United States)

    Walch, Stephen P.; Rohlfing, Celeste Mcmichael


    The results of CASSCF multireference contracted CI calculations with large ANO basis sets are presented for the exchange region of the HO2 potential-energy surface. The saddle point for H atom exchange is about 13 kcal/mol below the energy of H + O2; therefore, this region of the surface should be accessible during H + O2 recombination and methathesis reactions.

  8. New Volleyballenes: Y20C60, La20C60, and Lu20C60


    Wang, Jing; Liu, Ying


    New stable Volleyballenes Y20C60, La20C60, and Lu20C60 molecular clusters have been proposed using first-principles density functional theory studies. In conjunction with recent findings for the scandium system, these findings establish Volleyballene M20C60 molecules as a stable general class of fullerene family. All M20C60 (M=Y, La, and Lu) molecules have Th point group symmetries and relatively large HOMO-LUMO gaps.

  9. In Vivo Measurement and Characterization of a Novel Formulation of [177Lu]-DOTA-Octreotate

    Directory of Open Access Journals (Sweden)

    Dale Bailey


    Full Text Available Objective(s:Lutetium-177 can be made with high specific activity and with no other isotopes of lutetium present, referred to as “No Carrier Added” (NCA 177Lu. We have radiolabelled DOTA-conjugated peptide DOTA‐(Tyr3‐octreotate with NCA 177Lu (“NCA-LuTATE” and used it in nearly 40 therapeutic administrations for subjects with neuroendocrine tumours or meningiomas. In this paper, we report on our initial studies on aspects of the biodistribution and dosimetry of NCA-LuTATE from gamma camera 2D whole body (WB and quantitative 3D SPECT (qSPECT 177Lu imaging. Methods: Thirteen patients received 39 NCA-LuTATE injections. Extensive WB planar and qSPECT imaging was acquired at approximately 0.5, 4, 24 and 96 h to permit estimates of clearance and radiation dose estimation using MIRD-based methodology (OLINDA-EXM. Results:The average amount of NCA-Lutate administered per cycle was 7839±520 MBq. Bi-exponential modelling of whole body clearance showed half lives for the fast & slow components of t½=2.1±0.6 h and t½=58.1±6.6 h respectively. The average effective dose to kidneys was 3.1±1.0 Gy per cycle. In eight patients completing all treatment cycles the average total dose to kidneys was 11.7±3.6 Gy. Conclusions: We have shown that NCA-LuTATE has an acceptable radiation safety profile and is a suitable alternative to Carrier-Added 177Lu formulations. The fast component of the radiopharmaceutical clearance was closely correlated with baseline renal glomerular filtration rate, and this had an impact on radiation dose to the kidneys. In addition, it has less radioactive waste issues and requires less peptide per treatment.

  10. Observations of OH and HO2 radicals in coastal Antarctica

    Directory of Open Access Journals (Sweden)

    S. J.-B. Bauguitte


    Full Text Available OH and HO2 radical concentrations have been measured in the boundary layer of coastal Antarctica for a six-week period during the austral summer of 2005. The measurements were performed at the British Antarctic Survey's Halley Research Station (75° 35' S, 26° 19' W, using the technique of on-resonance laser-induced fluorescence to detect OH, with HO2 measured following chemical conversion through addition of NO. The mean radical levels were 3.9×105 molecule cm−3 for OH, and 0.76 ppt for HO2 (ppt denotes parts per trillion, by volume. Typical maximum (local noontime levels were 7.9×105 molecule cm−3 and 1.50 ppt for OH and HO2 respectively. The main sources of HOx were photolysis of O3 and HCHO, with potentially important but uncertain contributions from HONO and higher aldehydes. Of the measured OH sinks, reaction with CO and CH4 dominated, however comparison of the observed OH concentrations with those calculated via the steady state approximation indicated that additional co-reactants were likely to have been present. Elevated levels of NOx resulting from snowpack photochemistry contributed to HOx cycling and enhanced levels of OH, however the halogen oxides IO and BrO dominated the CH3O2 – HO2 – OH conversion in this environment, with associated ozone destruction.

  11. The electron capture in {sup 163}Ho experiment

    Energy Technology Data Exchange (ETDEWEB)

    Hassel, Clemens [Kirchhoff-Institute for Physics, Heidelberg University (Germany); Collaboration: ECHo-Collaboration


    The Electron Capture {sup 163}Ho experiment, ECHo, aims to investigate the electron neutrino mass in the sub-eV range by means of the analysis of the calorimetrically measured energy spectrum following the electron capture process of {sup 163}Ho. The {sup 163}Ho spectrum will be measured with array of low temperature metallic magnetic calorimeters (MMCs). With a first prototype of MMC having the {sup 163}Ho source embedded in the absorber, we performed the first high energy resolution measurement of the EC spectrum. The achieved energy resolution was Δ E{sub FWHM} = 7.6 eV and the signal rise-time was τ = 130 ns. We aim to improve the performance of the detector to reach an energy resolution Δ E{sub FWHM} < 5 eV and a signal rise-time τ < 100 ns. We present the plan for a medium scale experiment, ECHo-1k, in which about 1000 Bq of high purity {sup 163}Ho will be implanted in the optimized detectors. With about one year of measuring time and with a better knowledge of the EC spectral shape, which will be reached thanks to dedicated experiments, we will be able to achieve a sensitivity on the electron neutrino mass below 10 eV/c{sup 2}, improving the present limit of about one order of magnitude.

  12. LU-HF Age of Martian Meteorite Larkman Nunatek 06319 (United States)

    Shafer, J. T.; Brandon, A. D.; Lapen, T. J.; Righter, M.; Beard, B.; Peslier, A. H.


    Lu-Hf isotopic data were collected on mineral separates and bulk rock powders of LAR 06319, yielding an age of 197+/- 29 Ma. Sm-Nd isotopic data and in-situ LA-ICP-MS data from a thin section of LAR 06319 are currently being collected and will be presented at the 2009 LPSC. These new data for LAR 06319 extend the existing data set for the enriched shergottite group. Martian meteorites represent the only opportunity for ground truth investigation of the geochemistry of Mars [1]. At present, approximately 80 meteorites have been classified as Martian based on young ages and distinctive isotopic signatures [2]. LAR 06319 is a newly discovered (as part of the 2006 ANSMET field season) martian meteorite that represents an important opportunity to further our understanding of the geochemical and petrological constraints on the origin of Martian magmas. Martian meteorites are traditionally categorized into the shergottite, nakhlite, and chassignite groups. The shergottites are further classified into three distinct isotopic groups designated depleted, intermediate, and enriched [3,4] based on the isotope systematics and compositions of their source(s).

  13. Local structure and bonding of Er in GaN: A contrast with Er in Si

    Energy Technology Data Exchange (ETDEWEB)

    Citrin, P. H. [Bell Labs, Lucent Technologies, Murray Hill, New Jersey 07974 (United States); Northrup, P. A. [Bell Labs, Lucent Technologies, Murray Hill, New Jersey 07974 (United States); Birkhahn, R. [University of Cincinnati, Nanoelectronics Laboratory, Cincinnati, Ohio 45221 (United States); Steckl, A. J. [University of Cincinnati, Nanoelectronics Laboratory, Cincinnati, Ohio 45221 (United States)


    X-ray absorption measurements from relatively high concentrations of Er (>0.1 at. %) doped in GaN films show that Er occupies the Ga site with an unprecedentedly short Er-N bond length. Electroluminescence intensities from these GaN:Er films correlate with the concentration of Er atoms that replace Ga, not with the abundantly present O impurities in the host. Simple chemical concepts are used to explain each of these results and their striking difference from those obtained for Er-doped Si. (c) 2000 American Institute of Physics.

  14. Embedding of $^{163}$Ho and $^{166m}$ Ho in the energy absorbers of low temperature metallic magnetic calorimeters

    CERN Multimedia

    The calorimetric measurement of the $^{163}$Ho electron capture spectrum is a promising tool to investigate the electron neutrino mass. A suitable method to embed the source in the detectors is the ion-implantation. This process has already been used to embed $^{163}$Ho ions in micro-fabricated low temperature metallic magnetic prototypes. The $^{163}$Ho electron capture spectrum obtained with these first prototypes is presently the most precise with an energy resolution of $\\Delta$$\\textit{E}$$_{FWHM}$ = 7.6 eV. In order to test the performance of the new generation of low temperature metallic magnetic calorimeters, we propose to perform a $^{163}$Ho ion-implantation on the new chip having two arrays consisting of 32 pixels each. An activity of about 1 Bq per pixel is required. With this new detector array we will be able to achieve a better energy resolution and to acquire a higher statistics which allows for studying the $^{163}$Ho spectral shape. We propose also to perform an ion-implantation of $^{166m}$...

  15. Consumer Acceptance of Functional Foods in Ho Chi Minh City

    Directory of Open Access Journals (Sweden)

    Duy Tung BUI


    Full Text Available The aim of this paper is to identify and evaluate the underlying factors affecting consumer acceptance of functional foods. The contribution of this study is to better understand customer willingness to buy such products in Ho Chi Minh City by shedding light on how socio-demographic, cognitive and attitudinal determinants affect consumer's choices of foods. We conducted a survey using 217 respondents from Ho Chi Minh City. Next, we develop a binary-probit model to quantify the impact of each factor on consumer acceptance. The results show that having a sick relative, beliefs in health benefits positively affect acceptance level. Other than that, old people in Ho Chi Minh City tend to reject the use of functional foods. However, when they are provided with enough knowledge, they are the most intensive buyers of these products. Implications and further researches are also discussed.

  16. Preparation, structure and photoluminescence of nanoscaled-Nd: Lu{sub 3}Al{sub 5}O{sub 12}

    Energy Technology Data Exchange (ETDEWEB)

    Ding Lihua [Anhui Provincial Key Lab of Optical Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Zhang, Qingli, E-mail: [Anhui Provincial Key Lab of Optical Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031 (China); Luo Jianqiao; Liu Wenpeng [Anhui Provincial Key Lab of Optical Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031 (China); Zhou Wenlong [Anhui Provincial Key Lab of Optical Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Yin Shaotang [Anhui Provincial Key Lab of Optical Devices and Materials, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031 (China)


    Highlights: > Nd:Lu{sub 3}Al{sub 5}O{sub 12} (Nd:LuAG) nano-crystalline was synthesized by co-precipitation method, its polycrystalline phase can be formed above 900 deg. C and its structure was refined by Rietveld method. > From the point of structure, studies on the difference of crystal field interaction between Nd:LuAG and Nd:YAG were carried out. > Compared with Nd:YAG, Nd:LuAG has broader absorption FWHM at 808 nm, longer fluorescence lifetime and larger emission cross section. - Abstract: Nd:Lu{sub 3}Al{sub 5}O{sub 12} (Nd:LuAG) nano-crystalline was synthesized by co-precipitation method. Its phase transformation, structure, absorption and photoluminescence properties were studied. The Nd:LuAG polycrystalline phase is formed above 900 deg. C and its particle sizes are in the range of 18-36 nm. The structure of Nd:LuAG was refined by Rietveld method. The lattice parameters and the distortion of Lu{sup 3+}-O{sup 2-} polyhedron in Nd:LuAG are larger than that of in pure LuAG. Because the distortion of Lu{sup 3+}-O{sup 2-} polyhedron is larger than that of Y{sup 3+}-O{sup 2-} polyhedron in YAG and the distance of Lu{sup 3+}-O{sup 2-} is smaller than that of Y{sup 3+}-O{sup 2-} in YAG, Nd{sup 3+} in LuAG experiences a stronger crystal field effect, which is proved by the crystal field strength and the chemical environment parameter. The absorption spectrum shows that Nd:LuAG has a broad absorption band at 808 nm with FWHM above 6 nm, which is favorable for improving laser efficiency. The fluorescence lifetime from {sup 4}F{sub 3/2} {yields} {sup 4}I{sub 11/2} transition is 320 {mu}s and longer than that of Nd:YAG. The longer lifetime is propitious to energy storage. The emission cross section at 1064 nm is 2.89 x 10{sup -19} cm{sup 2}, taking into account the Boltzmann distribution of the excited state. The emission cross section in Nd:LuAG is also larger than that of Nd:YAG, which is useful for laser operation. All results indicate that Nd:LuAG is a promising

  17. ER Stress and Lipid Metabolism in Adipocytes

    Directory of Open Access Journals (Sweden)

    Beth S. Zha


    Full Text Available The role of endoplasmic reticulum (ER stress is a rapidly emerging field of interest in the pathogenesis of metabolic diseases. Recent studies have shown that chronic activation of ER stress is closely linked to dysregulation of lipid metabolism in several metabolically important cells including hepatocytes, macrophages, β-cells, and adipocytes. Adipocytes are one of the major cell types involved in the pathogenesis of the metabolic syndrome. Recent advances in dissecting the cellular and molecular mechanisms involved in the regulation of adipogenesis and lipid metabolism indicate that activation of ER stress plays a central role in regulating adipocyte function. In this paper, we discuss the current understanding of the potential role of ER stress in lipid metabolism in adipocytes. In addition, we touch upon the interaction of ER stress and autophagy as well as inflammation. Inhibition of ER stress has the potential of decreasing the pathology in adipose tissue that is seen with energy overbalance.

  18. Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics (United States)

    Bravo, Roberto; Gutierrez, Tomás; Paredes, Felipe; Gatica, Damián; Rodriguez, Andrea E.; Pedrozo, Zully; Chiong, Mario; Parra, Valentina; Quest, Andrew F.G.; Rothermel, Beverly A.; Lavandero, Sergio


    Endoplasmic reticulum (ER) stress activates an adaptive unfolded protein response (UPR) that facilitates cellular repair, however, under prolonged ER stress, the UPR can ultimately trigger apoptosis thereby terminating damaged cells. The molecular mechanisms responsible for execution of the cell death program are relatively well characterized, but the metabolic events taking place during the adaptive phase of ER stress remain largely undefined. Here we discuss emerging evidence regarding the metabolic changes that occur during the onset of ER stress and how ER influences mitochondrial function through mechanisms involving calcium transfer, thereby facilitating cellular adaptation. Finally, we highlight how dysregulation of ER–mitochondrial calcium homeostasis during prolonged ER stress is emerging as a novel mechanism implicated in the onset of metabolic disorders. PMID:22064245

  19. Different technical possibilities of post-therapeutic tandem 90Y/ /177Lu-DOTATATE imaging. (United States)

    Kunikowska, Jolanta; Bajera, Adam; Sawicka, Magdalena; Czwarnowski, Piotr; Pawłowicz, Bożena; Aksamit, Dariusz; Pawlak, Dariusz; Królicki, Leszek


    Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms derived from endocrine stem cells.These tumors are characterized by overexpression of somatostatin receptors (SSTR), which is utilized for imaging using SSTR analogs. Peptide receptor radionuclide therapy (PRRT) somatostatin analogs labeled with 90Y and 177Lu in neuroendocrine tumors (NETs) results in symptomatic improvement, prolonged survival,and enhanced quality of life. The post-therapeutic imaging leadsto possibility of biodistribution of therapy. The aim of our study was to describe different possibilities of post-therapeutic imaging in patients underwent tandem therapy 90Y/177Lu-DOTATATE with preliminary results of 90Y PET imaging. Thirty patients (11 men, 19 women; the mean age 55 ± 10.9 y) with histological confirmation of metastatic neuroendocrine tumors (G1 and G2) were treated with tandem therapy 90Y/177Lu-DOTATATE. WHBA scan and SPECT acquisition of the abdomen were performed 24 hours post therapy injection, on the dual-head Varicam camera (ELSCINT) using 177Lu photopeak and 90Y bremsstrahlung. PET imaging of 90Y component was done on Siemens Biograph Truepoint PET/CT (window 511 keV ± 15%)4 hours after 90Y/177Lu-DOTATATE. Additionally phantom studies were performer to analyze the spatial resolution of different protocols. Out of all the patients, median OS was 49.8 months and median EFS time 24.3 months. Spatial resolution achieved for 90Y, 177 Lu and PET imaging of 90Y component measured using the phantom of the torso filled up with water was 20 mm, 8 mm and 4-5 mm FWHM, respectively. Spatial resolution in human body in our study was about 30 mm for 90Y, 15 mm for 177Lu and 25-30 mm for PET imaging of 90Y component. The theoretically best spatial resolution offers PET scanner, however it is important to keep in mind that 90Y-imaging PET is not used for diagnosis purposes (small activities)but rather to present new possibility of post-therapeutic imaging (substantially higher

  20. Dyskalkuli - er det et overset problem?

    DEFF Research Database (Denmark)

    Johansen, Lene Østergaard


    norm) til at klare sig i nutidens og fremtidens samfund. I de senere år er vi i Danmark begyndt at søge viden om elevers vanskeligheder med at lære matematik; et arbejde, der er stærkt støttet af en række nordiske kollegaer. Vanskeligheder med at lære matematik er et meget komplekst og mangesidigt...

  1. Fanggitter beskytter svage køer

    DEFF Research Database (Denmark)

    Thomsen, Peter


    KvægInfo nr.: 1574  Dato: 13-02-2006  Forfatter: Peter Thomsen   Fanggitter beskytter svage køer Ny forskning dokumenterer, at foderbord med fanggitter giver færre aggressioner og beskytter de svage køer. Selvom køernes samlede ædetid er den samme i staldsystemer med henholdsvis fanggitter og...

  2. Physical optimization of production by deuteron irradiation of high specific activity (177g)Lu suitable for radioimmunotherapy. (United States)

    Manenti, Simone; Bonardi, Mauro L; Gini, Luigi; Groppi, Flavia


    Deuteron-induced nuclear reactions for generation of no-carrier-added (NCA) Lu isotopes were investigated using the stacked-foil activation technique on natural Yb targets at energies up to Ed=18.18MeV. The decay curve of ¹⁷⁷Yb, the growth curve of the cumulative (direct and indirect) and the direct production of (177g)Lu were determined. The analysis of these curves conducts to the evidence that the predominant route for the production of (177g)Lu is the indirect reaction ¹⁷⁶Yb(d,p)¹⁷⁷Yb, which decays to (177g)Lu. In the spectra acquired one year from the EOB the γ lines of (177m)Lu are not evident. A comparison between the calculated activity of (177g)Lu produced with a cyclotron and with a nuclear reactor is given. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. Trifluralin: photolysis under sunlight conditions and reaction with HO* radicals. (United States)

    Le Person, A; Mellouki, A; Muñoz, A; Borras, E; Martin-Reviejo, M; Wirtz, K


    The gas phase atmospheric degradation of trifluralin (a widely used herbicide) has been investigated at the EUPHORE facility. Its photolysis has been studied under sunlight conditions and its reaction rate constant with HO() radicals was measured using the relative rate method. Using 1,3,5-trimethylbenzene as reference compound, the rate constant of HO() reaction with trifluralin was obtained to be [formula: see text] The mean photolysis rate measured under solar radiation was [formula: see text] . The photolysis of trifluralin was found to generate organic aerosols with a yield of (20 +/-10)%. The data obtained enabled us to discuss the atmospheric fate of trifluralin in the gas phase.

  4. DEM generation using ERS-ENVISAT interferometry (United States)

    Wegmüller, Urs; Santoro, Maurizio; Werner, Charles; Strozzi, Tazio; Wiesmann, Andreas; Lengert, Wolfgang


    Space-borne SAR interferometry is one possible method for the generation of digital elevation models (DEMs). The sensitivity of this technique depends strongly on system parameters as the time interval between the observations used and the spatial baseline. Longer time intervals are less suited because of temporal decorrelation of the signal. Longer spatial baselines result in an increased height sensitivity. ERS-2 and ENVISAT ASAR operate in identical orbits at slightly different sensor frequencies with ASAR preceding ERS-2 by 28 min. This configuration offers a unique opportunity to study and apply ERS-ENVISAT interferometry. ERS-2-ENVISAT ASAR IS2 VV-polarization interferograms are characterized by a short 28 min repeat-pass interval and a long 1.5-2.5 km baseline. Given the long baseline and short time interval ERS-ENVISAT interferometry has a good potential for the generation of precise DEMs in relatively flat areas. The idea to use ERS-ENVISAT interferometry for DEM generation is not new, nevertheless, very few adequate data sets were identified and analyzed in the past. Now, thanks to a recent dedicated ERS-2-ENVISAT Tandem mission of ESA many well suited data sets became available. In this paper the ERS-ENVISAT interferometry methodology is described, its feasibility is demonstrated by presenting ERS-ENVISAT interferometry DEMs over several sites, and its potential is assessed.

  5. Er virksomheder deres sociale ansvar voksent?

    DEFF Research Database (Denmark)

    Øhrgaard, Per


    Eftertanken. Virksomheder er i dag ramt af en CSR-bølge. Men hvis definitionen af, hvad et samfundsmæssigt ansvar er, glider over på virksomhedernes hænder, glider det væk fra alle os andre.......Eftertanken. Virksomheder er i dag ramt af en CSR-bølge. Men hvis definitionen af, hvad et samfundsmæssigt ansvar er, glider over på virksomhedernes hænder, glider det væk fra alle os andre....

  6. {sup 166}Ho-chitosan as a radiation synovectomy agent - biocompatibility study of {sup 166}Ho-chitosan in rabbits

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sug Jun; Lee, Soo Yong; Jeon, Dae Geun; Lee Jong Seok [Korea Cancer Center Hospital, Seoul (Korea, Republic of)


    Radiation synovectomy is a noninvasive therapy that has been investigated as an alternative to surgical synovectomy. It is been successfully employed in the treatment of synovitis in rheumatoid arthrits and other inflammatory arthropathies. We developed the {sup 166}Ho-chitosan complex for possible use as a radiation synovectomy agent. Holmium is the more practical isotope based on its higher radioactivity and logner half-life. And isotope based on its higher radioactivity and logner half-life. And chitosan is ideal and suitable particles based on its soluble and biodegradable characteristics. So we investigated the biocompatibility of the {sup 166}Ho-chitosan complex to evaluated the suitability as a radiation synovectomy agent. In this study, we performed in vivo and in vitro stability test and biodistribution test. Our results indicate that {sup 166}Ho-chitosan may be an effective radiopharmaceutical for radiation synovectomy. (author). 30 refs., 7 tabs.

  7. Dynamic Friction Parameter Identification Method with LuGre Model for Direct-Drive Rotary Torque Motor


    Wang, Xingjian; Lin, Siru; Wang, Shaoping


    Attainment of high-performance motion/velocity control objectives for the Direct-Drive Rotary (DDR) torque motor should fully consider practical nonlinearities in controller design, such as dynamic friction. The LuGre model has been widely utilized to describe nonlinear friction behavior; however, parameter identification for the LuGre model remains a challenge. A new dynamic friction parameter identification method for LuGre model is proposed in this study. Static parameters are identified t...

  8. Production, biodistribution assessment and dosimetric evaluation of 177Lu-TTHMP as an agent for bone pain palliation


    Zolghadri, Samaneh; Yousefnia,Hassan; Jalilian, Amir Reza; Ghannadi-Maragheh, Mohammad


    Objective(s): Recently, bone-avid radiopharmaceuticals have been shown to have potential benefits for the treatment of widespread bone metastases. Although 177Lu-triethylene tetramine hexa methylene phosphonic acid (abbreviated as 177Lu-TTHMP), as an agent for bone pain palliation, has been evaluated in previous studies, there are large discrepancies between the obtained results. In this study, production, quality control, biodistribution, and dose evaluation of 177Lu-TTHMP have been investig...

  9. E0 decay of the 0{sup +}{sub 2} levels in {sup 156}Dy and {sup 160}Er

    Energy Technology Data Exchange (ETDEWEB)

    Lo Bianco, G; Nardelli, S; Gupta, S Das; Saltarelli, A [School of Science and Technology, University of Camerino and INFN - Sez. Perugia (Italy); Balabanski, D L [INRNE, Bulgarian Academy of Sciences, Sofia (Bulgaria); Blasi, N [INFN - Sez. Milano (Italy); Gladnishki, K [Faculty of Physics, St. Kliment Ohridski University of Sofia (Bulgaria); Fortunato, L, E-mail: balabanski@inrne.bas.b [ECT, Trento (Italy)


    The branching between the E0 0{sup +}{sub 2} {yields} 0{sup +}{sub 1} and the E2 0{sup +}{sub 2} {yields} 2{sup +}{sub 2} transitions in {sup 156}Dy and {sup 160}Er were measured following the {epsilon} decay of {sup 156}Ho and {sup 160}Tm. A potential of the 4th order of the deformation parameter {beta}, the {sup L}o Bianco potential{sup ,} was chosen to describe the U(5) - SU(3) first order shape phase transition, covering the whole transitional path. The comparison of the excitation spectra and the measured ratios of reduced transition probabilities, X(E0/E2), with the calculations, indicates that {sup 156}Dy is in the spherical region, while {sup 160}Er is located in the deformed region, but quite close to the critical point.

  10. Effective lattice stabilization of gadolinium aluminate garnet (GdAG via Lu3+ doping and development of highly efficient (Gd,LuAG:Eu3+ red phosphors

    Directory of Open Access Journals (Sweden)

    Jinkai Li, Ji-Guang Li, Zhongjie Zhang, Xiaoli Wu, Shaohong Liu, Xiaodong Li, Xudong Sun and Yoshio Sakka


    Full Text Available The metastable garnet lattice of Gd3Al5O12 is stabilized by doping with smaller Lu3+, which then allows an effective incorporation of larger Eu3+ activators. The [(Gd1−xLux1−yEuy]3Al5O12 (x = 0.1–0.5, y = 0.01–0.09 garnet solid solutions, calcined from their precursors synthesized via carbonate coprecipitation, exhibit strong luminescence at 591 nm (the 5D0 → 7F1 magnetic dipole transition of Eu3+ upon UV excitation into the charge transfer band (CTB at ~239 nm, with CIE chromaticity coordinates of x = 0.620 and y = 0.380 (orange-red. The quenching concentration of Eu3+ was estimated at ~5 at.% (y = 0.05, and the quenching was attributed to exchange interactions. Partial replacement of Gd3+ with Lu3+ up to 50 at.% (x = 0.5 while keeping Eu3+ at the optimal content of 5 at.% does not significantly alter the peak positions of the CTB and 5D0 → 7F1 emission bands but slightly weakens both bands owing to the higher electronegativity of Lu3+. The effects of processing temperature (1000–1500 °C and Lu/Eu contents on the intensity, quantum efficiency, lifetime and asymmetry factor of luminescence were thoroughly investigated. The [(Gd0.7Lu0.30.95Eu0.05]3Al5O12 phosphor processed at 1500 °C exhibits a high internal quantum efficiency of ~83.2% under 239 nm excitation, which, in combination with the high theoretical density, favors its use as a new type of photoluminescent and scintillation material.

  11. Radiolabeling parameters of {sup 177}Lu-DOTA-RITUXIMAB

    Energy Technology Data Exchange (ETDEWEB)

    Massicano, Adriana V.F.; Alcarde, Lais F.; Oliveira, Ricardo S.; Mengatti, Jair; Araujo, Elaine B. de, E-mail: [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)


    Cancer treatment using radioimmunotherapy (RIT) has been the focus of much research in the last two decades. In RIT, a radioisotope is coupled to a monoclonal antibody (mAb) to form a tumor-specific target agent to improve the cytocidal effect of the mAbs. RIT allows the systemic delivery of radiation to disease target by mAbs while sparing normal tissues. Rituximab® (Mabthera - Roche) is a chimeric mouse-human monoclonal antibody; it selectively binds with high affinity to the CD20 antigen, a hydrophobic transmembrane protein, which is expressed on B-lymphocytes and in more than 90% of B cell non-Hodgkin's lymphomas (NHL). The conjugation and radiolabeling process involve special conditions of pH and temperature, long processes of manipulation and mixing. All this process can damage the antibody structure and compromise its clinical application. Therefore, these parameters must be largely studied. The aim of this work was to evaluate the best radiolabeling conditions of DOTA-rituximab. Briefly, 10 mg of antibody previously purified by ultrafiltration device was conjugated with DOTA-NHS-ester (Macrocyclics) in 50 fold molar excess. The reaction was conducted for 1 hour in phosphate buffer pH 8.0 and gently mixing at room temperature, remaining for 24 hours under refrigeration. The immunoconjugated was purified by size exclusion column and ultrafiltration device. The radiolabeled parameters studied were: immunoconjugated mass, activity of {sup 177}LuCl{sub 3}, reaction time, temperature and pH. The radiochemical purity of the preparations was determined using analysis by thin layer chromatography (TLC-SG plates). The best studied condition presented radiochemical purity above 95% and the integrity of antibody was preserved. (author)

  12. Er:YAG pre-treatment for bonding of orthodontic bracket: 1 year of in vitro treatment

    Directory of Open Access Journals (Sweden)

    de Jesus Tavarez RR


    Full Text Available Rudys Rodolfo de Jesus Tavarez,1 Gisele Lima Bezerra,2 Karla Janilee de Souza Penha,3 Carlos Rocha Gomes Torres,4 Leily Macedo Firoozmand5 1Department of Dentistry, Ceuma University (UNICEUMA, 2Dentistry Program, Ceuma University (UNICEUMA, 3Dentistry Program, Federal University of Maranhão, UFMA, São Luís, MA, 4Restorative Dentistry Department, ICT UNESP University, São Paulo, 5Dentistry Department I, Federal University of Maranhão,UFMA, São Luís, MA, Brazil Objective: The aim of this study was to evaluate in vitro bond strength of metal brackets bonded with: total etch, total etch with erbium: yttrium aluminum garnet laser (Er:YAG and self-etching adhesive systems, submitted to thermal-mechanical cycling, simulating 1 year of orthodontic treatment.Materials and methods: For the study, 80 bovine incisors were randomly divided into 3 experimental groups (n=16 each: XT- acid etching + Transbond XT, XT/Er:YAG- Transbond XT associated with Er:YAG laser irradiation (λ=2.94 μm, 60 mJ, 10 Hz and SEP- Transbond Plus Self Etching Primer. Samples were submitted to thermal-mechanical cycling, simulating 1 year of orthodontic treatment. Afterward, the shear bond strength test was performed in a universal test machine at a speed of 0.5mm/min. Samples were evaluated under a stereomicroscope and by scanning electron microscopy for analysis of enamel surface and adhesive remnant index. Data were analyzed using Kruskal–Wallis and Mann–Whitney (with Bonferroni correction statistical tests.Results: Statistically significant difference was observed between the groups studied (p<0.05. Groups XT and SEP showed the highest bond strength values, without statistical difference between them, while group XT/Er:YAG showed reduction in bond strength values. Higher frequency of adhesive failures between enamel and adhesive system was verified for groups XT and XT/Er:YAG.Conclusion: The conventional (XT and self-etching (SEP adhesive systems showed mean bond

  13. Preparation of LuAG Powders with Single Phase and Good Dispersion for Transparent Ceramics Using Co-Precipitation Method

    Directory of Open Access Journals (Sweden)

    Liangjie Pan


    Full Text Available The synthesis of pure and well dispersed lutetium aluminum garnet (LuAG powder is crucial and important for the preparation of LuAG transparent ceramics. In this paper, high purity and well dispersed LuAG powders have been synthesized via co-precipitation method with lutetium nitrate and aluminum nitrate as raw materials. Ammonium hydrogen carbonate (AHC was used as the precipitant. The influence of aging time, pH value, and dripping speed on the prepared LuAG powders were investigated. It showed that long aging duration (>15 h with high terminal pH value (>7.80 resulted in segregation of rhombus Lu precipitate and Al precipitate. By decreasing the initial pH value or accelerating the dripping speed, rhombus Lu precipitate was eliminated and pure LuAG nano powders were synthesized. High quality LuAG transparent ceramics with transmission >75% at 1064 nm were fabricated using these well dispersed nano LuAG powders.

  14. Ungdomslitteratur former(er) sig

    DEFF Research Database (Denmark)

    Henkel, Ayoe Qvist


    Igennem en 'mediesensitiv' analyse af romanen "Akavet" af Ronnie Andersen (2014) og perspektivering til andre aktuelle romaner for og med unge undersøger artiklen, hvordan ungdomslitteratur udvikler sig i dialog med digitale og mediebaserede impulser, og hvilke konsekvenser for udsigelserne om...... ungdomsliv og ungdomslitteraturens æstetik og mulige egenart, denne udvikling har. Artiklen baserer sig på en materialitetstilgang særligt inspireret af N. Katherine Hayles, som ikke tidligere har fået opmærksomhed i læsninger af ungdomslitteratur eller i diskussioner af ungdomslitteraturens mulige egenart......, at ungdomslitteratur drejer sig om unges udviklingsproces fra barndom og til voksenhed og dermed skildrer en overgang præget af linearitet, modning og vækst. Artiklen konkluderer, at der er ungdomslitteratur, der realiseres på andre præmisser, og Akavet kan ses som eksponent for en bevægelse fra ungdomslitteratur som...

  15. Stínová kinematografie - Mytologie australského gotického filmu 70.let


    Kotrlová, Jitka


    8 Univerzita Karlova v Praze Filozofická fakulta Katedra filmových studií Diplomová práce Jitka Kotrlová Stínová kinematografie: mytologie australského gotického filmu 70. let Shadow Cinematography: Mythology of the Australian Gothic Film of the 1970's Praha 2015 Vedoucí práce: PhDr. Petra Hanáková, Ph.D Abstract: The thesis focuses on the mythological aspects of films of the so-called Australia gothic in 1970's. In a detailed form of thematic analysis it discovers three fundamental myths wit...

  16. Reflexe podílu vichystického režimu na šoa ve francouzské kinematografii


    Rábová, Michaela


    This bachelor thesis focuses on the difficulties French people meet when dealing with their war history when the Vichy regime collaborated with Nazis on the persecution and deportation of Jewish people. This topic is exclusively examined from the point of view of French cinema between 1945 and 2010. By analyzing the films concentrated on Shoah, the thesis shows the development of portraying Vichy's involvement in the genocide. The main aim is to answer the question on how was this issue shown...

  17. Bývalá kino-kavárna v areálu brněnského výstaviště

    Czech Academy of Sciences Publication Activity Database

    Bláha, Jiří; Stará, J.

    -, č. 2 (2009), s. 83-112 ISSN 1212-1487 Institutional research plan: CEZ:AV0Z20710524 Keywords : funkcionalism * reinforced concrete structure * cinema Subject RIV: AL - Art, Architecture , Cultural Heritage

  18. Testování inhibičního potenciálu reaktivátorů lidské acetylcholinesterasy in vitro


    Šepsová, Vendula


    Charles University in Prague Faculty of Pharmacy in Hradec Kralove Department of Farmacology and Toxicology Candidate: Mgr. Vendula Šepsová Supervisor: PharmDr. Jana Ţďárová Karasová, PhD. Consultant: PharmDr. Marie Vopršalová, Csc. Title of thesis: Inhibition potencial of human acetylcholinesterase reactivators in vitro testing Tested reactivators are substances with oxime moiety attached to a ring with quaternary nitrogen, which enable binding to active site of acetylcholinesterase (AChE). ...

  19. Studium sterilizačních účinků dielektrického bariérového výboje


    Slámová, Jitka


    Předmětem dizertační práce bylo studium sterilizačních účinků dielektrického bariérového výboje pracujícího za atmosférického tlaku. Jako modelové mikroorganismy byly při studiu použity plíseň Aspergillus niger, grampozitivní bakterie Bacillus subtilis a částečně také gramnegativní bakterie Escherichia coli. Vzorky mikroorganismů byly naneseny na papír Whatman 1 nebo PET folii a vystaveny účinkům plazmatu. Plazma bylo generováno v prostředí argonu, dusíku, suchého a vlhkého vzduchu s frekvenc...

  20. On the Impact of HO2-H2O Complexes in the Marine Boundary Layer: A Possible Sink for HO2

    Directory of Open Access Journals (Sweden)

    Alexander Thomas Archibald


    Full Text Available The impact of the formation of HO2-H2O adducts following reaction between H2O and HO2 and subsequent reaction of this adduct on HOx, H2O2 and O3 as a function of relative humidity in the marine boundary layer has been investigated using a zero-dimensional box model. The results of simulations with different product yields for the reaction of HO2-H2O with HO2 were compared with base case data derived from current recommendations for tropospheric modelling. It is suggested that inclusion of reactions of the HO2-H2O adduct may provide a significant sink for HO2 which has so far not been considered in models of tropospheric chemistry and depending on reaction products may have a significant impact on H2O2 and O3.

  1. Emergence and present status of Lu-177 in targeted radiotherapy. The Indian scenario

    Energy Technology Data Exchange (ETDEWEB)

    Banerjee, S.; Das, T.; Chakraborty, S.; Venkatesh, M. [Bhabha Atomic Reseach Centre, Trombay, Mumbai (India). Radiopharmaceuticals Div.


    {sup 177}Lu is presently considered to be a potential radionuclide for the development of agents for radionuclide therapy owing to its favorable nuclear decay characteristics [T{sub 1/2} = 6.65 d, E{sub {beta}}{sub (max)} = 0.497 MeV, E{sub {gamma}} = 113 KeV (6.4%) and 208 KeV (11%)]. While the long half-life of this promising radioisotope offers distinct logistic advantage, particularly, in countries having limited reactor facilities, the feasibility of its large-scale production with adequate specific activity and excellent radionuclidic purity in medium flux research reactors constitute yet another desirable feature. Extensive studies have been carried out to optimize the production of this isotope, with high specific activity and radionuclidic purity by the (n,{gamma}) route using the highest available flux and the optimum irradiation time. The gradual evolution of clin ical grade {sup 177}LuCl{sub 3} as a new radiochemical, ready for commercial deployment by Radiopharmaceuticals Division, Bhabha Atomic Research Centre, to nuclear medicine centers all over India was accomplished in 2010 in a stepwise manner with the commencement of the production of high specific activity {sup 177}Lu from enriched target in 2001. Research on {sup 177}Lu has demonstrated its immense potential in radiotherapeutic applications, a direct outcome of which has resulted in indigenous development of two agents viz. {sup 177}Lu-EDTMP and {sup 177}Lu-DOTA-TATE presently being evaluated in human patients for palliative care of bone pain due to skeletal metastases and treatment of malignancies of neuroendocrine origin, respectively. Using locally produced {sup 177}Lu, the radiolabeling of a plethora of other molecules with potential applicability in radiation synovectomy and targeted therapy of malignant tumors have been successfully demonstrated. A few of these agent such as a novel {sup 177}Lu-labeled porphyrin has shown considerable promise in initial studies and is presently evaluated

  2. The prosecution of Taiwan sexuality researcher and activist Josephine Ho. (United States)

    Wang, Ping


    In April 2003, following a newspaper report of a hyperlink to a website on bestiality on the Sexuality Databank website of the Center for the Study of Sexualities, National Central University, Taipei, Taiwan, 14 conservative NGOs filed charges against the Center's founder, Josephine Ho, for "propagating obscenities that corrupt traditional values." Ho has been researching sexuality and supporting freedom for marginalised sexual minorities for ten years. In a public statement in response to the charges, she said that the work of scholarly research must not be dictated by prejudice and that differences in sexual values should not be arbitrated by law and should be open for public discussion. As the legal process began in January 2004, Ho's supporters in Taiwan have called for the preservation of the Taiwan Constitutional decree on integrity and autonomy of academic research and freedom of expression on the internet, for the University to resist calls to dismiss Ho from her post, and for respect for freedom of speech and expression and the right to create spaces to educate people about non-normative sexualities.

  3. Phase equilibria of the Mo-Al-Ho ternary system

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yitai; Chen, Xiaoxian; Liu, Hao [Guangxi Univ., Nanning (China). College of Materials Science and Engineering; Guangxi Univ., Nanning (China). Guangxi Key Laboratory of Processing for Non-ferrous Metal and Featured Materials; Zhan, Yongzhong [Guangxi Univ., Nanning (China). College of Materials Science and Engineering; Guangxi Univ., Nanning (China). Guangxi Key Laboratory of Processing for Non-ferrous Metal and Featured Materials; Guangxi Univ., Nanning (China). Center of Ecological Collaborative Innovation for Aluminum Industry


    Investigation into the reactions and phase equilibria of transition metal elements (i.e. Mo, Zr, Cr, V and Ti), Al and rare earths is academically and industrially important for the development of both refractory alloys and lightweight high-temperature materials. In this work, the equilibria of the Mo-Al-Ho ternary system at 773 K have been determined by using X-ray powder diffraction and scanning electron microscopy equipped with energy dispersive X-ray analysis. A new ternary phase Al{sub 4}Mo{sub 2}Ho has been found and the other ternary phase Al{sub 43}Mo{sub 4}Ho{sub 6} is observed. Ten binary phases in the Al-Mo and Al-Ho systems, including Al{sub 17}Mo{sub 4} rather than Al{sub 4}Mo, have been determined to exist at 773 K. The homogeneity ranges of AlMo{sub 3} and Al{sub 8}Mo{sub 3} phase are 7.5 at.% and 1 at.%, respectively. According to the phase-disappearing method, the maximum solubility of Al in Mo is about 16 at.%.

  4. The electron capture in {sup 163}Ho experiment

    Energy Technology Data Exchange (ETDEWEB)

    Hassel, Clemens [Kirchhoff-Institute of Physics, Heidelberg University (Germany); Collaboration: ECHo-Collaboration


    The Electron Capture {sup 163}Ho experiment, ECHo, has the goal to probe the electron neutrino mass on a sub-eV level via the analysis of the calorimetrically measured electron capture spectrum (EC) of {sup 163}Ho. For this metallic magnetic calorimeters will be used. The performance achieved by a first prototype of MMC with embedded {sup 163}Ho already shows that the desired values of an energy resolution of ΔE{sub FWHM} < 3 eV and a signal risetime of τ < 1 μs for ECHo can be reached. Recently the energy available for the decay Q{sub EC} = 2833(30{sub stat})(15{sub sys}) eV/c{sup 2} has been precisely determined by ECHo. Given this Q{sub EC}-value we expect a sensitivity on the electron neutrino mass below 10 eV in the first phase of the ECHo experiment, ECHo-1k. In this phase a high purity {sup 163}Ho source with a total activity of 1 kBq will be measured by about 100 detectors operated in a dedicated cryogenic platform in a reduced background environment. The results from this experiment will define parameters to scale the experiment to the next phase of ECHo-1M. There the total activity of the source will be 1 MBq and it will be measured by using 10{sup 5} detectors. We present the current status of the ECHo experiment.

  5. Experimental dosimetry of Ho-166 bioglass seed polymer-protected

    Energy Technology Data Exchange (ETDEWEB)

    Nogueira, Luciana B.; Campos, Tarcisio P.R. [Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Dept. de Engenharia Nuclear. Programa de Pos-Graduacao em Ciencias e Tecnicas Nucleares


    This study aims to develop experimental dosimetry of Ho-166 bio glass seed for brachytherapy studies using GAFCHROMIC EBT2 radio chromium films. The methodology consists of placement of radio chromium films in a compressed breast phantom, along with bio glass polymer-protected seeds of [Si: Ca: Ho] and [Si: Ca: Ho: Zr]. The bio glass seeds were encapsulated with polyvinyl alcohol, before being activated and used in the study. The bio glass seeds were introduced into the breast phantom, along with radio chromium films for a period of 2 hours. After the exposure time, radio chromium films were removed from phantom and digitized for analysis in ImageDIG 2.0 program, which quantifies the intensity of RGB (Red, Green, Blue). The dose calculation was evaluated by Monte Carlo technique. Experimental and theoretical data were used to calibrate the dose distribution. The results were plotted on graphs and dose iso curves were obtained. As conclusion it is possible to perform dosimetry in Ho-166 seed brachytherapy using radio chromium films, limited to a short exposure time and small activity. (author)

  6. Temperature Variation of the Magnetic Structure of HoSb

    DEFF Research Database (Denmark)

    Andersen, Nils Axel; Kjems, Jørgen; Vogt, O.


    Neutron diffraction has been used to show that the magnetic moment vector in the antiferromagnet HoSb changes direction as a function of temperature below TN=5.7K. The experimental results are in qualitative agreement with a recent theoretical prediction by Jensen et al. (1980) which ascribe...

  7. Living with ghosts in Hořava-Lifshitz gravity

    Energy Technology Data Exchange (ETDEWEB)

    Ramazanov, S. [Gran Sasso Science Institute (INFN),Viale Francesco Crispi 7, I-67100 L’Aquila (Italy); Arroja, F. [Leung Center for Cosmology and Particle Astrophysics, National Taiwan University,No. 1, Sec. 4, Roosevelt Road, Taipei, 10617 Taipei, Taiwan (R.O.C.) (China); Celoria, M. [Gran Sasso Science Institute (INFN),Viale Francesco Crispi 7, I-67100 L’Aquila (Italy); Matarrese, S. [Dipartimento di Fisica e Astronomia “G. Galilei”, Università degli Studi di Padova,via Marzolo 8, I-35131 Padova (Italy); Gran Sasso Science Institute (INFN),Viale Francesco Crispi 7, I-67100 L’Aquila (Italy); INFN, Sezione di Padova,via Marzolo 8, I-35131 Padova (Italy); INAF-Osservatorio Astronomico di Padova,Vicolo dell’Osservatorio 5, I-35122 Padova (Italy); Pilo, L. [Dipartimento di Scienze Fisiche e Chimiche, Università di L’Aquila,I-67010 L’Aquila (Italy); INFN, Laboratori Nazionali del Gran Sasso,I-67010 Assergi (Italy)


    We consider the branch of the projectable Hořava-Lifshitz model which exhibits ghost instabilities in the low energy limit. It turns out that, due to the Lorentz violating structure of the model and to the presence of a finite strong coupling scale, the vacuum decay rate into photons is tiny in a wide range of phenomenologically acceptable parameters. The strong coupling scale, understood as a cutoff on ghosts’ spatial momenta, can be raised up to Λ∼10 TeV. At lower momenta, the projectable Hořava-Lifshitz gravity is equivalent to General Relativity supplemented by a fluid with a small positive sound speed squared (10{sup −42}≲) c{sub s}{sup 2}≲10{sup −20}, that could be a promising candidate for the Dark Matter. Despite these advantages, the unavoidable presence of the strong coupling obscures the implementation of the original Hořava’s proposal on quantum gravity. Apart from the Hořava-Lifshitz model, conclusions of the present work hold also for the mimetic matter scenario, where the analogue of the projectability condition is achieved by a non-invertible conformal transformation of the metric.

  8. Systém integrovaného managementu


    Slavíček, Jakub


    Diplomová práce se zabývá zaváděním integrovaného systému managementu. Konkrétně zaváděním systému managementu kvality a systémem environmentálního managementu. Praktická část obsahuje přezkoumání současného stavu plnění požadavků norem ČSN EN ISO 9001/2009 a ČSN EN ISO 14001/2005, registr právních požadavků, identifikaci environmentálních aspektů a jejich zhodnocení z hlediska významnosti a identifikaci situací havarijního ohrožení. This thesis deals with the introduction of integrate man...

  9. HO2 and HO2* Radical Chemistry during PROPHET-AMOS: Measurement and Model Comparison HO2 and HO2* Radical Chemistry during PROPHET-AMOS: Measurement and Model Comparison (United States)

    Lew, M.; Bottorff, B.; Stevens, P. S.; Sigler, P. S. R.


    The hydroxyl (OH) and peroxy radicals, both the hydroperoxy radicals (HO2) and organic peroxy radicals (RO2) play an important role in atmospheric chemistry. In addition to controlling lifetimes of many trace gases important to issues of global climate change, reactions of these radicals can also lead to the production of ozone and secondary organic aerosols in the atmosphere. Previous measurements of these radicals in forest environments characterized by high mixing ratios of isoprene and low mixing ratios of NOx have shown serious discrepancies with modeled concentrations. These results bring into question our understanding of the atmospheric chemistry of isoprene and other biogenic VOCs under low NOxconditions. In the summer of 2016, HO2 and HO2* (S HO2 + αRO2) radicals were measured using the Laser-Induced Fluorescence Fluorescence Assay by Gas Expansion (LIF-FAGE) technique as part of the Program for Research on Oxidants: PHtochemistry, Emissions, and Transport- Atmospheric Measurements of Oxidants in Summer (PROPHET-AMOS). This campaign took place in a forested area in northern Michigan characterized by high mixing ratios of isoprene and low mixing ratios of NOx. Ambient measurements from this campaign will be compared to previous measurements at this site and to modeled predictions.

  10. Ocelová konstrukce zimního stadionu


    Lobreis, Jan


    Práce je zaměřena na posouzení stavby městského zimního stadionu, který bude umístěn v lokalitě Brno - Komárov. Zimní stadion je navržen dle směrnic ledního hokeje s kapacitou přibližně 7 000 diváků. Z toho 5 850 k sezení, 1 050 na stání a 100 ve VIP prostorech. Konstrukci zimního stadiónu tvoří ocelové a ocelobetonové sloupy, které společně se spřaženými příčnými průvlaky, železobetonovou deskou a ztužidly zajišťují tuhost konstrukce. Sloupy jsou podepřeny soustavou vrtaných pilot s hlavicem...

  11. Progress in the development of LuAlO3 based scintillators

    CERN Document Server

    Belsky, A; Lecoq, P; Dujardin, C; Garnier, N; Canibano, H; Pédrini, C; Petrosian, A


    LuAlO3:Ce3+ (LuAP) and LuxY1-xAlO3:Ce3+ (LuYAP) crystals are the promote scintillation materials for Positron Emission Tomography. Actual study of these scintillators develops in the tree directions: (i) growth of large size LuAP crystals with stable properties, (ii) relationship between composition of LuYAP crystals and scintillation properties, and (iii) scintillation mechanisms in lutetium compounds. After improving of growth conditions a large size samples (length greater than 40 mm) have been prepared. Crystals show a good correlation between growth parameters, light yield and transmission spectra. We performed a series of samples with calibrated size (2x2x10 mm3) and compare the light yield with a standard BGO and LSO samples. Mixed crystals with composition of 0.6 less than x less than 0.8 show a significant increase of light yield. We suggest that the short order clusterisation in mixed crystals may by playing an important role in governing the scintillation efficiency. In order to clarify the scintil...

  12. Production of {sup 177}Lu, a potential radionuclide for diagnostic and therapeutic applications

    Energy Technology Data Exchange (ETDEWEB)

    Khandaker, Mayeen Uddin; Kassim, Hasan Abu [Department of Physics, University of Malaya, 50603 Kuala Lumpur (Malaysia); Haba, Hiromitsu [Nishina Center for Accelerator-Based Science, RIKEN, Wako, Saitama 351-0198 (Japan)


    {sup 177g}Lu (T{sub 1/2}=6.647d; E{sub β{sup −max}}=498.3KeV, I{sub β{sup −total}}=100%; E{sub γ} = 112.9498 keV, I{sub γ} = 6.17%; E{sub γ} = 208.3662 keV, I {sub γ} = 10.36%) is widely used in many clinical procedures due to its excellent decay characteristics. Production cross-sections of the {sup nat}Yb(d,x){sup 177g}Lu reactions have been measured from a 24-MeV deuteron energy down to the threshold by using a stacked-foil activation technique combined with high resolution γ-ray spectrometry. An overall good agreement is found with some of the earlier measurements, whereas a partial agreement is obtained with the theoretical data extracted from the TENDL-2013 library. Physical thick target yield for the {sup 177g}Lu radionuclide was deduced using the measured cross-sections. The deduced yield curves indicate that a low energy (<11 MeV) cyclotron and a highly enriched {sup 176}Yb target could be used to obtain {sup 177g}Lu with negligible impurity from {sup 177m}Lu.

  13. First results on prototype production of new LuYAP crystals

    CERN Document Server

    Annenkov, A N; Korzhik, M; Lecoq, P; Missevitch, O V


    A small animal positron emission tomograph, ClearPET, is under development by the Crystal Clear Collaboration at CERN. ClearPET, a detector with Depth Of Interaction (DOI) determination capability is based on LSO:Ce and (Lu //0//.//7-Y//0//.//3)AlO//3:Ce ((Lu-Y)AP:Ce or LuYAP) scintillation crystals assembled in two-layer matrix with PMT readout. The key point of the ClearPET challenge was the development of the mass production technology of Lu-based scintillation crystals with perovskite structure. The LuYAP scintillation crystal has been proposed several years ago but its mass production technology could only be managed now, through tremendous efforts of the Crystal Clear Collaboration and of its industrial partners. Crystal ingots 18-25mm in diameter and 170-210mm in length are available now. In this paper, we discuss the results of the crystal mass production technology development and its application in detecting modules.

  14. Complex cytokine modulation of a continuous line of mink lung epithelial cells (Mv1Lu). (United States)

    Kelley, J; Baldor, L; Absher, M


    The continuous mink lung epithelial cell line Mv1Lu has proven to be a sensitive reporter line in the bioassay for purified TGF-beta, exhibiting a sigmoid-shaped concentration-response relationship with an EC50 of 12 pM (0.3 ng/mL). Maximal inhibition of Mv1Lu cells generates a 75-95% decrement in the number of adherent cells. However, this bioassay is not specific for TGF-beta as originally claimed. Mv1Lu cells are sensitive to other cytokines and substances found in complex biological fluids. In this study the effects of other biological response modifiers in this assay were tested and several were found to have important growth modulatory capacities that confound the quantitation of TGF-beta. EGF, TGF-alpha, fibronectin, and IGF-I all induce Mv1Lu cell proliferation. In contrast, neither PDGF (-AA, -AB, -BB) nor endotoxin ( or = 10 ng/mL) are the only cytokines examined that inhibit Mv1Lu proliferation. TGF-beta decreases final cell number both by preventing mitosis and by inhibition of adherence of cells to the uncoated dish. Several strategies are suggested to assure the specificity of this otherwise convenient bioassay for TGF-beta.

  15. Luminescence and scintillation properties of LuPO{sub 4}-Ce nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Vistovskyy, V., E-mail: [Ivan Franko National University of Lviv, 8 Kyryla i Mefodiya, 79005 Lviv (Ukraine); Malyy, T. [Ivan Franko National University of Lviv, 8 Kyryla i Mefodiya, 79005 Lviv (Ukraine); Pushak, A. [Ukraine Academy of Printing, 19 Pidgolosko Str., 79020 Lviv (Ukraine); Vas’kiv, A. [Ivan Franko National University of Lviv, 8 Kyryla i Mefodiya, 79005 Lviv (Ukraine); Shapoval, A.; Mitina, N. [Lviv Polytechnic National University, 12 S. Bandera, 79013 Lviv (Ukraine); Gektin, A. [Institute for Scintillation Materials, NAS of Ukraine, 60 Lenina Avenue, 61001 Kharkiv (Ukraine); Zaichenko, A. [Lviv Polytechnic National University, 12 S. Bandera, 79013 Lviv (Ukraine); Voloshinovskii, A. [Ivan Franko National University of Lviv, 8 Kyryla i Mefodiya, 79005 Lviv (Ukraine)


    Study of the spectral-luminescence parameters of LuPO{sub 4}-Ce nanoparticles upon the excitation by X-ray quanta and synchrotron radiation with photon energies of 4–25 eV was performed. Nanoparticles with mean size about a=35 nm and nanoparticles with size less than 12 nm reveal the different structures of cerium centers. Luminescence efficiency of LuPO{sub 4}-Ce nanoparticles of a<12 nm size strongly decreases upon the excitation in the range of band-to-band transitions as well as in the case of X-ray excitation. -- Highlights: • Luminescence of LuPO{sub 4}-Ce nanoparticles studied using synchrotron and X-ray excitation. • Different structure of Ce{sup 3+}-centers has been revealed for LuPO{sub 4}-Ce nanoparticles. • Luminescence of LuPO{sub 4}-Ce with size less than 12 nm is strongly quenched upon the X-ray excitation.

  16. Absence of justice : Lu Chengming's struggle for compensation

    Energy Technology Data Exchange (ETDEWEB)

    Bai, L.


    This article described the efforts of Chinese citizen Lu Chengming to claim compensation from the Chinese government after being forcibly re-located during the building of the Three Gorges hydroelectric project. Research conducted by the author revealed that many households were not compensated for being resettled, and that many people who had lived in the region became refugees. Lu Chengming's family became unemployed after his hotel was demolished in 2002. The family of 11 was then divided into 4 in order to further reduce the amount of subsidies owed to them. Appeals to higher authorities began in 1993. Since then, Lu Chengming has only received the most basic welfare assistance. This article provided a translation of Lu Chengming's testimony as well as his account of the resettlement procedures. It was concluded that while the Chinese government consistently refuses his claims, Lu Chengming continues to live in hope that the government will award him his settlement. 4 refs., 3 figs.

  17. A process for the separation of {sup 177}Lu from neutron irradiated {sup 176}Yb targets

    Energy Technology Data Exchange (ETDEWEB)

    Horwitz, E.P. [PG Research Foundation, Inc., 8205 S. Cass Ave., Suite 106, Darien, IL 60561 (United States)]. E-mail:; McAlister, D.R. [PG Research Foundation, Inc., 8205 S. Cass Ave., Suite 106, Darien, IL 60561 (United States); Bond, A.H. [PG Research Foundation, Inc., 8205 S. Cass Ave., Suite 106, Darien, IL 60561 (United States); Barrans, R.E. [PG Research Foundation, Inc., 8205 S. Cass Ave., Suite 106, Darien, IL 60561 (United States); Williamson, J.M. [Eichrom Technologies, Inc., 8205 S. Cass Ave., Suite 106, Darien, IL 60561 (United States)


    A conceptual flowsheet has been developed for the separation of {sup 177}Lu from a 300 mg neutron irradiated {sup 176}Yb enriched target. The key component of the process is an extraction chromatographic (EXC) resin containing 2-ethylhexyl 2-ethylhexylphosphonic acid (HEH[EHP]) sorbed onto a 25-53 {mu}m Amberchrom CG-71 substrate. The process is divided into three sections: (1) front-end target removal system (2) primary separation system and (3) secondary separation system. Each section involves the separation of Yb and Lu using the HEH[EHP] resin followed by concentration and acid adjustment of the Lu-rich eluate using an EXC material containing a diglycolamide extractant. The use of the diglycolamide EXC material is a significant feature of the flowsheet, allowing one to avoid lengthy evaporations and acidity adjustments between successive HEH[EHP] column runs while removing adventitious impurities from the {sup 177}Lu. The overall recovery of {sup 177}Lu is estimated at 73% with an overall decontamination factor from Yb of 10{sup 6}. The overall processing time can be as short as 4 h.

  18. Production of 177Lu, a potential radionuclide for diagnostic and therapeutic applications (United States)

    Khandaker, Mayeen Uddin; Haba, Hiromitsu; Kassim, Hasan Abu


    177gLu (T1/2=6.647d; Eβ-max=498.3 KeV, Iβ-total=100 % ; Eγ = 112.9498 keV, Iγ = 6.17%; Eγ = 208.3662 keV, I γ = 10.36%) is widely used in many clinical procedures due to its excellent decay characteristics. Production cross-sections of the natYb(d,x)177gLu reactions have been measured from a 24-MeV deuteron energy down to the threshold by using a stacked-foil activation technique combined with high resolution γ-ray spectrometry. An overall good agreement is found with some of the earlier measurements, whereas a partial agreement is obtained with the theoretical data extracted from the TENDL-2013 library. Physical thick target yield for the 177gLu radionuclide was deduced using the measured cross-sections. The deduced yield curves indicate that a low energy (<11 MeV) cyclotron and a highly enriched 176Yb target could be used to obtain 177gLu with negligible impurity from 177mLu.

  19. Er der en underviser til stede?

    DEFF Research Database (Denmark)

    Christiansen, René Boyer; Nortvig, Anne-Mette; Rosenlund, Lea Tilde


    I de senere år er MOOC (Massive Open Online Courses) blevet en faktor på uddannelsesområdet. MOOC-forskning er et forholdsvist nyt felt, men har inden for de seneste 2-3 år udviklet sig med hastige skridt (Liyanagunawardena et al. 2013, Bayne & Ross 2014). En stor del af denne forskning har haft...

  20. Hvorfor er Ernæringsdiagnosen vigtig?

    DEFF Research Database (Denmark)

    Winther, Eva


    Nutrition Care Process er en cirkulær firetrinsmodel for individuel eller gruppevis diætbehandling eller kostvejledning. Efter indsamling af oplysninger om klientens spisevaner bliver oplysningerne grupperet og analyseret, og der formuleres en syntese/ernæringsdiagnose. Ernæringsdiagnosen er en...

  1. "Det man siger er man selv..."

    DEFF Research Database (Denmark)

    Næsby, Torben; Nørgaard, Britta; Uddholm, Mats

    forhold, der er hermeneutisk, strukturelt og relationelt bestemt. Praksisviden kan ikke være objektiv i gængs forstand, men det behøver ikke at diskvalificere denne viden. Forståelse er altid knyttet til den sag og bundet til den situation man står overfor og i som professionel og som menneske....

  2. Der er kun én verden

    DEFF Research Database (Denmark)

    Hansen, Nils Gunder


    Klummeskriveren er langt væk hjemmefra, og globaliseringen går endelig op for ham, da han ser Golden Gate Bridge i San Francisco......Klummeskriveren er langt væk hjemmefra, og globaliseringen går endelig op for ham, da han ser Golden Gate Bridge i San Francisco...

  3. Coronavirus infection, ER stress and Apoptosis

    Directory of Open Access Journals (Sweden)



    Full Text Available The replication of coronavirus, a family of important animal and human pathogens, is closely associated with the cellular membrane compartments, especially the endoplasmic reticulum (ER. Coronavirus infection of cultured cells was previously shown to cause ER stress and induce the unfolded protein response (UPR, a process that aims to restore the ER homeostasis by global translation shutdown and increasing the ER folding capacity. However under prolonged ER stress, UPR can also induce apoptotic cell death. Accumulating evidence from recent studies has shown that induction of ER stress and UPR may constitute a major aspect of coronavirus-host interaction. Activation of the three branches of UPR modulates a wide variety of signaling pathways, such as mitogen-activated protein (MAP kinases activation, autophagy, apoptosis and innate immune response. ER stress and UPR activation may therefore contribute significantly to the viral replication and pathogenesis during coronavirus infection. In this review, we summarize current knowledge on coronavirus-induced ER stress and UPR activation, with emphasis on their cross-talking to apoptotic signaling.

  4. Multikulturalisme er en ny slags Apartheid

    DEFF Research Database (Denmark)

    Dyrberg, Torben Bech


    I en ny antologi retter forfatterne et kritisk lys mod forsvarerne af multikulturalisme. Og det er der god grund til, mener en af bogens redaktører. For den store gruppe, der hylder multikulturen, glemmer i al dens godhed, at de samtidig er med til at undergrave demokratiet og styrke uheldige mag...

  5. Problematika jihovýchodního pokračování lužického zlomu v západním Podkrkonoší

    Czech Academy of Sciences Publication Activity Database

    Prouza, V.; Coubal, Miroslav; Adamovič, Jiří


    Roč. 2012, Prosinec (2013), s. 59-63 ISSN 0514-8057 Institutional support: RVO:67985831 Keywords : Lusatian Fault * Koberovy Flexure * reverse faulting * Krkonoše piedmont region Subject RIV: DB - Geology ; Mineralogy

  6. X-ray resonant magnetic scattering investigations of hexagonal multiferroics RMnO3 (R = Dy, Ho, Er)

    Energy Technology Data Exchange (ETDEWEB)

    Nandi, Shibabrata [Iowa State Univ., Ames, IA (United States)


    Electricity and magnetism were unified into a common subject by James Clerk Maxwell in the nineteenth century yielding the electromagnetic theory. Four equations govern the dynamics of electric charges and magnetic fields, commonly known as Maxwell's equations. Maxwell's equations demonstrate that an accelerated charged particle can produce magnetic fields and a time varying magnetic field can induce a voltage - thereby linking the two phenomena. However, in solids, electric and magnetic ordering are most often considered separately and usually with good reason: the electric charges of electrons and ions are responsible for the charge effects, whereas the electron spin governs magnetic properties.

  7. Geometric calibration of ERS satellite SAR images

    DEFF Research Database (Denmark)

    Mohr, Johan Jacob; Madsen, Søren Nørvang


    Geometric calibration of the European Remote Sensing (ERS) Satellite synthetic aperture radar (SAR) slant range images is important in relation to mapping areas without ground reference points and also in relation to automated processing. The relevant SAR system parameters are discussed and calib......Geometric calibration of the European Remote Sensing (ERS) Satellite synthetic aperture radar (SAR) slant range images is important in relation to mapping areas without ground reference points and also in relation to automated processing. The relevant SAR system parameters are discussed...... on a seven-year ERS-1 and a four-year ERS-2 time series, the long term stability is found to be sufficient to allow a single calibration covering the entire mission period. A descending and an ascending orbit tandem pair of the ESA calibration site on Flevoland, suitable for calibration of ERS SAR processors...

  8. TumorHoPe: a database of tumor homing peptides.

    Directory of Open Access Journals (Sweden)

    Pallavi Kapoor

    Full Text Available Cancer is responsible for millions of immature deaths every year and is an economical burden on developing countries. One of the major challenges in the present era is to design drugs that can specifically target tumor cells not normal cells. In this context, tumor homing peptides have drawn much attention. These peptides are playing a vital role in delivering drugs in tumor tissues with high specificity. In order to provide service to scientific community, we have developed a database of tumor homing peptides called TumorHoPe.TumorHoPe is a manually curated database of experimentally validated tumor homing peptides that specifically recognize tumor cells and tumor associated microenvironment, i.e., angiogenesis. These peptides were collected and compiled from published papers, patents and databases. Current release of TumorHoPe contains 744 peptides. Each entry provides comprehensive information of a peptide that includes its sequence, target tumor, target cell, techniques of identification, peptide receptor, etc. In addition, we have derived various types of information from these peptide sequences that include secondary/tertiary structure, amino acid composition, and physicochemical properties of peptides. Peptides in this database have been found to target different types of tumors that include breast, lung, prostate, melanoma, colon, etc. These peptides have some common motifs including RGD (Arg-Gly-Asp and NGR (Asn-Gly-Arg motifs, which specifically recognize tumor angiogenic markers. TumorHoPe has been integrated with many web-based tools like simple/complex search, database browsing and peptide mapping. These tools allow a user to search tumor homing peptides based on their amino acid composition, charge, polarity, hydrophobicity, etc.TumorHoPe is a unique database of its kind, which provides comprehensive information about experimentally validated tumor homing peptides and their target cells. This database will be very useful in

  9. Magnetocaloric properties of the pseudo-binary Er-rich lanthanide dialuminide compounds (United States)

    Lima, A. L.


    The compounds (REEr)Al (where RE=Gd, Ho, Pr for x⩾0.75) were studied experimentally and theoretically in order to evaluate their magnetocaloric properties and suitability for use as working media in magnetic refrigeration devices operating at low temperatures. I propose a theoretical description of these systems which are composed of two rare-earth ions with different total angular momentum ( JRE1 and JRE2) Our model Hamiltonian is solved self-consistently, taking into account crystal electric fields, exchange interactions, the Zeeman effect and second-order effects. From the eigenvalues and eigenstates, the partition function from which thermodynamic quantities may be calculated is obtained, including the isothermal magnetic entropy change, Δ Smag. In order to validate the theoretical results, Δ Smag obtained from heat capacity measurements using Maxwell's relations is compared to the calculated one. The results indicate that for Er-rich compositions fairly good agreement between theoretical and experimental Δ Smag is obtained.

  10. Production, quality control, biodistribution assessment and preliminary dose evaluation of (177)Lu-PDTMP as a possible bone palliative agent. (United States)

    Yousefnia, Hassan; Jalilian, Amir R; Zolghadri, Samaneh; Ghannadi-Maragheh, Mohammad


    In this study, production, quality control, and biodistribution studies of a newly developed therapeutic compound have been presented and are followed by dosimetric evaluation for use in humans based on biodistribution data in wild-type rats. The Lu-1,2-propylene di-amino tetramethylenephosphonic acid (Lu-PDTMP) complex was prepared successfully using synthesized PDTMP ligand and LuCl3. LuCl3 was obtained by thermal neutron irradiation (4×10 n/cm/s) of enriched Lu2O3 samples. The radiochemical purity of Lu-PDTMP was checked by instant thin-layer chromatography. Stability studies of the complex in the final preparation and in the presence of human serum were performed for up to 72 h. The biodistribution of Lu-PDTMP and LuCl3 in wild-type rats was checked in animal tissues for up to 7 days. The absorbed dose of each human organ was calculated by means of the medical internal radiation dose method. Lu was produced with a specific activity of 100-110 GBq/mg. Lu-PDTMP was prepared with high radiochemical purity of greater than 99% and specific activity of 278 GBq/mmol. The complex demonstrated significant stability at room temperature. The agent demonstrated major accumulation in the bone tissue and a high target/nontarget uptake ratio. Dosimetric results showed that all tissues receive an insignificant absorbed dose in comparison with bone tissue. The results showed that Lu-PDTMP has considerably better properties compared with clinically used bone-seeking radiopharmaceuticals and therefore can be a good candidate for bone pain palliative therapy in skeletal metastases; however, further biological studies in other mammals are still needed.

  11. Effect of reducing Lu.sup.3+./sup. content on the fabrication and scintillation properties of non-stoichiometric Lu.sub.3-x./sub.Al.sub.5./sub.O.sub.12./sub.:Ce ceramics

    Czech Academy of Sciences Publication Activity Database

    Liu, S.; Mareš, Jiří A.; Babin, Vladimir; Hu, C.; Kou, H.; D'Ambrosio, C.; Pan, Y.; Nikl, Martin


    Roč. 63, Jan-Sl (2017), s. 179-184 ISSN 0925-3467 R&D Projects: GA ČR GAP204/12/0805 Institutional support: RVO:68378271 Keywords : LuAG:Ce ceramics * Lu 3+ deficiency * scintillation light yield * non-stoichiometry * antisite defects Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.238, year: 2016

  12. Scintillation properties of a La, Lu-admix gadolinium pyrosilicate crystal

    Energy Technology Data Exchange (ETDEWEB)

    Kurosawa, Shunsuke, E-mail: [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Shishido, Toetsu; Suzuki, Akira; Sugawara, Takamasa; Nomura, Akiko; Yubuta, Kunio [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Shoji, Yasuhiro [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yokota, Yuui [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Pejchal, Jan [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Institute of Physics, AS CR, Cukrovarnická 10, 162 53 Prague (Czech Republic); Ohashi, Yuji [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Kamada, Kei [New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research (IMR), Tohoku University 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe) 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); C& A Corporation, 6-6-40 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8577 (Japan)


    In order to obtain new scintillator with higher effective atomic number, a pyrosilicate crystal with a composition (Ce{sub 0.01}, Gd{sub 0.54}, La{sub 0.25}, Lu{sub 0.20}){sub 2}Si{sub 2}O{sub 7} (Ce:LaLu-GPS) was grown by the floating zone method. Emission wavelengths of this material were at 370 and 390 nm. Gamma-ray-excited pulse height and scintillation decay measurement showed that Ce:LaLu-GPS had a light output of 34,000±2000 photons/MeV, an FWHM energy resolution of 6.9±0.2%, and the decay time components of 59±1 ns (13%) and 570±20 ns (87%)

  13. Crystal fields at light rare-earth ions in Y and Lu

    DEFF Research Database (Denmark)

    Touborg, P.; Nevald, Rolf; Johansson, Torben


    in Y and Lu hosts, indicating that these values for a specific rare-earth solute in Y and Lu may give a reliable estimate for the corresponding sites in rare-earth metal. This is confirmed for Pr, for which these values and the value of B20 deduced from paramagnetic-susceptibility measurements......Crystal-field parameters have been deduced for the light rare-earth solutes Ce, Pr, and Nd in Y or Lu hosts from measurements of the paramagnetic susceptibilities. In the analysis all multiplets in the lowest LS term were included. For a given host, crystal-field parameters divided by Stevens...... on the pure metal, correctly explain the transition observed by neutron spectroscopy and the level crossing observed in a high-field experiment. A weighted average of B20 for cubic and hexagonal sites in Nd and Sm was obtained from the paramagnetic susceptibilities of these metals at high temperatures....

  14. Toxicity of trastuzumab labeled {sup 177}Lu on MCF7 and SKBr3 cell lines

    Energy Technology Data Exchange (ETDEWEB)

    Rasaneh, Samira [Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran (Iran, Islamic Republic of); Rajabi, Hossein, E-mail: [Department of Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-331, Tehran (Iran, Islamic Republic of); Hossein Babaei, Mohammad; Johari Daha, Fariba [Department of Radioisotope, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of)


    In this study, we labeled trastuzumab with {sup 177}Lu to synthesize a new radiopharmaceutical for therapy of breast cancer and at the first stage investigated its therapeutic effects on SKBr3 and MCF7 breast cancer cell lines. Trastuzumab-{sup 177}Lu showed very good in-vitro characteristics such as high radiochemical purity (91{+-}0.9%), good stability in PBS buffer (86{+-}2.3%) and blood serum (81{+-}2.7%) up to 96 h, appropriate immunoreactivity (85.4{+-}1.1%) and high cytotoxicity in HER2 expression cells. 5 fold increase in toxicity of trastuzumab-{sup 177}Lu was observed when compared with unlabeled trastuzumab on SKBr3 cells.

  15. Predictor-Corrector LU-SGS Discontinuous Galerkin Finite Element Method for Conservation Laws

    Directory of Open Access Journals (Sweden)

    Xinrong Ma


    Full Text Available Efficient implicit predictor-corrector LU-SGS discontinuous Galerkin (DG approach for compressible Euler equations on unstructured grids is investigated by adding the error compensation of high-order term. The original LU-SGS and GMRES schemes for DG method are discussed. Van Albada limiter is employed to make the scheme monotone. The numerical experiments performed for the transonic inviscid flows around NACA0012 airfoil, RAE2822 airfoil, and ONERA M6 wing indicate that the present algorithm has the advantages of low storage requirements and high convergence acceleration. The computational efficiency is close to that of GMRES scheme, nearly 2.1 times greater than that of LU-SGS scheme on unstructured grids for 2D cases, and almost 5.5 times greater than that of RK4 on unstructured grids for 3D cases.

  16. Effects of Lu and Tm Doping on Thermoelectric Properties of Bi2Te3 Compound (United States)

    Yaprintsev, Maxim; Lyubushkin, Roman; Soklakova, Oxana; Ivanov, Oleg


    The Bi2Te3, Bi1.9Lu0.1Te3 and Bi1.9Tm0.1Te3 thermoelectrics of n-type conductivity have been prepared by the microwave-solvothermal method and spark plasma sintering. These compounds behave as degenerate semiconductors from room temperature up to temperature T d ≈ 470 K. Within this temperature range the temperature behavior of the specific electrical resistivity is due to the temperature changes of electron mobility determined by acoustic and optical phonon scattering. Above T d, an onset of intrinsic conductivity takes place when electrons and holes are present. At the Lu and Tm doping, the Seebeck coefficient increases, while the specific electrical resistivity and total thermal conductivity decrease within the temperature 290-630 K range. The increase of the electrical resistivity is related to the increase of electron concentration since the Tm and Lu atoms are donor centres in the Bi2Te3 lattice. The increase of the density-of-state effective mass for conduction band can be responsible for the increase of the Seebeck coefficient. The decrease of the total thermal conductivity in doped Bi2Te3 is attributed to point defects like the antisite defects and Lu or Tm atoms substituting for the Bi sites. In addition, reducing the electron thermal conductivity due to forming a narrow impurity (Lu or Tm) band having high and sharp density-of-states near the Fermi level can effectively decrease the total thermal conductivity. The thermoelectric figure-of-merit is enhanced from ˜ 0.4 for undoped Bi2Te3 up to ˜ 0.7 for Bi1.9Tm0.1Te3 and ˜ 0.9 for Bi1.9Lu0.1Te3.

  17. Temperature evolution of magnetic structure of HoFeO3 by single crystal neutron diffraction

    Directory of Open Access Journals (Sweden)

    T. Chatterji


    Full Text Available We have investigated the temperature evolution of the magnetic structures of HoFeO3 by single crystal neutron diffraction. The three different magnetic structures werevfound as a function of temperature for HoFeO3. In all three phases the fundamental coupling between the Fe sub-lattices remains the same and only their orientation and the degree of canting away from the ideal axial direction varies. The magnetic polarisation of the Ho sub-lattices in these two higher temperature regions, in which the major components of the Fe moment lie along x and y, is very small. The canting of the moments from the axial directions is attributed to the antisymmetric interactions allowed by the crystal symmetry. In the low temperature phase two further structural transitions are apparent in which the spontaneous magnetisation changes sign with respect to the underlying antiferromagnetic configuration. In this temperature range the antisymmetric exchange energy varies rapidly as the the Ho sub-lattices begin to order. So long as the ordered Ho moments are small the antisymmetric exchange is due only to Fe-Fe interactions, but as the degree of Ho order increases the Fe-Ho interactions take over whilst at the lowest temperatures, when the Ho moments approach saturation the Ho-Ho interactions dominate. The reversals of the spontaneous magnetisation found in this study suggest that in HoFeO3 the sums of the Fe-Fe and Ho-Ho antisymmetric interactions have the same sign as one another, but that of the Ho-Fe terms is opposite.

  18. Isomeric ratio measurements for the radiative neutron capture 176Lu(n,γ) at DANCE (United States)

    Denis-Petit, D.; Roig, O.; Méot, V.; Morillon, B.; Romain, P.; Jandel, M.; Kawano, T.; Vieira, D. J.; Bond, E. M.; Bredeweg, T. A.; Couture, A. J.; Haight, R. C.; Keksis, A. L.; Rundberg, R. S.; Ullmann, J. L.


    The isomeric ratios for the neutron capture reaction 176Lu(n,γ) to the Jπ = 5/2-, 761.7 keV, T1/2 = 32.8 ns and the Jπ = 15/2+, 1356.9 keV, T1/2 = 11.1 ns levels of 177Lu, have been measured for the first time with the Detector for Advanced Neutron Capture Experiments (DANCE) at the Los Alamos National Laboratory. These measured isomeric ratios are compared with TALYS calculations.

  19. Production of non carrier added (n.c.a.) {sup 177}Lu for radiopharmaceutical applications

    Energy Technology Data Exchange (ETDEWEB)

    Barkhausen, Christoph


    The goal of this dissertation was the development of a process to produce non carrier added {sup 177}Lu at the FRM II. For this purpose, preparative chromatographic methods were evaluated and applied. The highest quality of the nuclide which could only be achieved through a complex chemical process, has been already been proven by clinical studies to be very advantageous. The process has been built up in a hot cell as a semi-automated process and is now being adapted to the requirements of the 'Arzneimittelgesetz' in order to establish n.c.a. {sup 177}Lu as a pharmaceutical product.

  20. Isomeric ratio measurements for the radiative neutron capture 176Lu(n,γ at DANCE

    Directory of Open Access Journals (Sweden)

    Denis-Petit D.


    Full Text Available The isomeric ratios for the neutron capture reaction 176Lu(n,γ to the Jπ = 5/2−, 761.7 keV, T1/2 = 32.8 ns and the Jπ = 15/2+, 1356.9 keV, T1/2 = 11.1 ns levels of 177Lu, have been measured for the first time with the Detector for Advanced Neutron Capture Experiments (DANCE at the Los Alamos National Laboratory. These measured isomeric ratios are compared with TALYS calculations.

  1. Improving quantitative dosimetry in (177)Lu-DOTATATE SPECT by energy window-based scatter corrections

    DEFF Research Database (Denmark)

    de Nijs, Robin; Lagerburg, Vera; Klausen, Thomas L


    and the activity, which depends on the collimator type, the utilized energy windows and the applied scatter correction techniques. In this study, energy window subtraction-based scatter correction methods are compared experimentally and quantitatively. MATERIALS AND METHODS: (177)Lu SPECT images of a phantom...... technique, the measured ratio was close to the real ratio, and the differences between spheres were small. CONCLUSION: For quantitative (177)Lu imaging MEGP collimators are advised. Both energy peaks can be utilized when the ESSE correction technique is applied. The difference between the calculated...

  2. Der er ingen stemmer i kulturpolitik

    DEFF Research Database (Denmark)

    Rasmussen, Casper Hvenegaard

    og forbedret adgang til dannelseskulturen. For det andet har begreber som habitus, kulturel kapital og distinktion været kvalitative forklaringer på de problemer, som demokratiseringen af dannelseskulturen er stødt på. For det tredje sætter Bourdieus sene og mere normative forfatterskab fokus på......Der er flere grunde til at Pierre Bourdieu er bruges flittigt i den kulturpolitiske forskning. For det første er Bourdieus studier af feltbegrebet, og særligt udviklingen af den kunstneriske felt, en hjørnesten i forståelsen af en moderne vestlig kulturpolitik, der bygger på offentlig kunststøtte......, hvordan markedstanken udfordrer kulturfeltets autonomi. Det er særligt kulturfeltets vigende autonomi i en dansk kulturpolitisk kontekst og forandringer i den kulturelle kapital, der er omdrejningspunktet for dette paper. Det er en Bourdieu-inspireret analyse af det offentligt støttede dansk kulturliv...

  3. Tl response of KMgF{sub 3}: Lu + PTFE at ultraviolet radiation; Respuesta Tl de KMgF{sub 3}: Lu + PTFE a radiacion ultravioleta

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, P.R. [Instituto Nacional de Investigaciones Nucleares, A.P. 18 -1027, 11801 Mexico D.F. (Mexico); Alarcon, N.G. [Facultad de Quimica, Universidad Autonoma del Estado de Mexico. Paseo Tollocan, Esq. con Jesus Carranza, 50180 Toluca, Estado de Mexico (Mexico); Furetta, C.; Azorin, J. [Universidad Autonoma Metropolitana- Iztapalapa, San Rafael Atlixco 186, 09340 Mexico. D.F. (Mexico)


    Ionizing radiation has different types of interaction with a crystalline solid. However, only few effects are interesting to optimize some thermoluminescent (Tl) properties of certain Tl materials. This paper presents results obtained by irradiating KMgF{sub 3}: Lu + Ptfe Tl dosimeters with ultraviolet (UV) radiation previously exposed to gamma radiation. These results showed that those dosimeters not exposed previously to gamma radiation did not presented any Tl signal. Meanwhile, those previously submitted to gamma irradiation showed that their sensitivity was increased as the gamma dose increased. The glow curve of sensitized KMgF{sub 3}: Lu + Ptfe exposed to UV radiation, presented the dosimetric pea at 212 C. This makes this material to be promissory for measuring UV radiation. (Author)

  4. Supervision og de tre k´er

    DEFF Research Database (Denmark)

    Schilling, Benedicte; Jacobsen, Claus Haugaard; Nielsen, Jan


    Kontrol, kontrakt og kontekst er supervisionens tre k'er. Men hvad er supervision i det hele taget for en størrelse, der spillerså central en rolle for den psykologfaglige profession?......Kontrol, kontrakt og kontekst er supervisionens tre k'er. Men hvad er supervision i det hele taget for en størrelse, der spillerså central en rolle for den psykologfaglige profession?...

  5. Overall survival and response pattern of castration-resistant metastatic prostate cancer to multiple cycles of radioligand therapy using [{sup 177}Lu]Lu-PSMA-617

    Energy Technology Data Exchange (ETDEWEB)

    Ahmadzadehfar, Hojjat; Wegen, Simone; Yordanova, Anna; Kuerpig, Stefan; Eppard, Elisabeth; Wei, Xiao; Schlenkhoff, Carl; Essler, Markus [University Hospital Bonn, Department of Nuclear Medicine, Bonn (Germany); Fimmers, Rolf [University of Bonn, Institute for Medical Biometry, Informatics and Epidemiology, Bonn (Germany); Hauser, Stefan [University Hospital Bonn, Department of Urology, Bonn (Germany)


    Up to 30% of patients with castration-resistant prostate cancer (CRPC) do not show any response to the first cycle of radioligand therapy (RLT) with [{sup 177}Lu]Lu-PSMA-617 (Lu-PSMA). We evaluated patient response to the second and third cycles of RLT in patients that underwent at least three cycles. The second aim of this study was to calculate the median overall survival (OS) of responders and non-responders after the first cycle and after all three cycles of RLT. CRPC patients were treated with Lu-PSMA, with a median interval of 8 weeks between each cycle. The tumour marker prostate-specific antigen (PSA) was used as the marker for response evaluation. Fifty-two patients underwent a total of 190 cycles of RLT (3-6 cycles per patient). Of these, 80.8% showed a decline in PSA 2 months after the first cycle, with 44.2% showing a PSA decline of ≥50%. When compared to baseline PSA, 73.1% showed a PSA decline after the third cycle. 50% of patients that did not show any response to the first cycle also did not respond to the second and third cycles. The median OS was 60 weeks in all patients. The median OS was significantly longer for patients that showed any PSA decline after the first cycle compared to patients without PSA decline (68 vs. 33 weeks). There was a significant difference in median OS between responders and non-responders for a change in PSA after the third cycle compared to baseline PSA. Patients with a positive response to RLT, regardless of the rate of decline, had a significantly longer median OS. Of the patients that did not show any response to the first cycle, 50% responded to the second or third cycles. (orig.)

  6. Hvordan er det å leve med CRPS?


    Hovind, Thomas


    Hensikten med denne studien er å se på hvordan pasienter med komplekst regionalt smertesyndrom (CRPS) opplever å leve med tilstanden og hvordan disse pasientene har opplevd å bli møtt i helsevesenet. CRPS er en langvarig tilstand med sterke smerter som kan medføre økt smerterespons, redusert funksjon og nedsatt livskvalitet hos pasientene. Studien er en kvalitativ undersøkelse basert på dybdeintervju av fire pasienter med CRPS. Pasientene ble rekruttert fra en smerteavdeling i Nord-Norge og u...

  7. Ytringsfriheden er ikke nødvendig

    DEFF Research Database (Denmark)

    Lauritzen, Pia


    nemlig godt konstatere, at ytringsfriheden ikke er nødvendig uden dermed at give afkald på frihed og demokrati.Vi kan oven i købet mene, at ytringsfriheden ophører med at være frihed, når vi betragter den som nødvendig. Og det er lige nøjagtig det, jeg efterlyser: at vi bruger filosoffer som Immanuel...... Kant og Luigi Pareyson til at forstå, at friheden er betydelig mere kompleks, end vi gør den til i øjeblikket....

  8. En hat er vel en hat ... eller?

    DEFF Research Database (Denmark)

    Bøilerehauge, Dorrit


    Mens vi kører i høj fart på "the information highway" - i den helt store bus midt på vejen - glemmer vi ofte noget meget vigtigt i vores glæde over, at verden tilsyneladende åbner sig for os, og vi kan kommunikere med hele verden med ét klik. Vi glemmer, at selvom trafikskilte som oftest er ens -...... - så er selve trafikken og forventningerne blandt medtrafikanterne helt forskellige fra det, vi er vant til. Udgivelsesdato: Februar...

  9. The chlamydial organism Simkania negevensis forms ER vacuole contact sites and inhibits ER-stress. (United States)

    Mehlitz, Adrian; Karunakaran, Karthika; Herweg, Jo-Ana; Krohne, Georg; van de Linde, Sebastian; Rieck, Elke; Sauer, Markus; Rudel, Thomas


    Most intracellular bacterial pathogens reside within membrane-surrounded host-derived vacuoles. Few of these bacteria exploit membranes from the host's endoplasmic reticulum (ER) to form a replicative vacuole. Here, we describe the formation of ER-vacuole contact sites as part of the replicative niche of the chlamydial organism Simkania negevensis. Formation of ER-vacuole contact sites is evolutionary conserved in the distantly related protozoan host Acanthamoeba castellanii. Simkania growth is accompanied by mitochondria associating with the Simkania-containing vacuole (SCV). Super-resolution microscopy as well as 3D reconstruction from electron micrographs of serial ultra-thin sections revealed a single vacuolar system forming extensive ER-SCV contact sites on the Simkania vacuolar surface. Simkania infection induced an ER-stress response, which was later downregulated. Induction of ER-stress with Thapsigargin or Tunicamycin was strongly inhibited in cells infected with Simkania. Inhibition of ER-stress was required for inclusion formation and efficient growth, demonstrating a role of ER-stress in the control of Simkania infection. Thus, Simkania forms extensive ER-SCV contact sites in host species evolutionary as diverse as human and amoeba. Moreover, Simkania is the first bacterial pathogen described to interfere with ER-stress induced signalling to promote infection. © 2014 John Wiley & Sons Ltd.

  10. Half-life measurement of the medical radioisotope 177Lu produced from the 176Yb(n,γ reaction

    Directory of Open Access Journals (Sweden)

    Ferreira K.M.


    Full Text Available 177Lu is a medium energy beta-emitter commonly used in Nuclear Medicine for radiotherapeutic applications. In this work, the half-life of 177Lu has been measured using a re-entrant ionisation chamber over a period of 82 days (approximately 12 half-lives. Unlike the majority of previous studies, the material used in this work was produced via the 176Yb(n,γ177Yb reaction followed by the β-decay to 177Lu, producing insignificant quantities of 177mLu. This has resulted in the most precise half-life measurement of 177Lu to date. A half-life of 6.6430 (11 days has been determined. This value is in statistical agreement with the currently recommended half-life of 6.6463 (15 days (z-score = 1.8.

  11. Facilitative plasma membrane transporters function during ER transit. (United States)

    Takanaga, Hitomi; Frommer, Wolf B


    Although biochemical studies suggested a high permeability of the endoplasmic reticulum (ER) membrane for small molecules, proteomics identified few specialized ER transporters. To test functionality of transporters during ER passage, we tested whether glucose transporters (GLUTs, SGLTs) destined for the plasma membrane are active during ER transit. HepG2 cells were characterized by low-affinity ER transport activity, suggesting that ER uptake is protein mediated. The much-reduced capacity of HEK293T cells to take up glucose across the plasma membrane correlated with low ER transport. Ectopic expression of GLUT1, -2, -4, or -9 induced GLUT isoform-specific ER transport activity in HEK293T cells. In contrast, the Na(+)-glucose cotransporter SGLT1 mediated efficient plasma membrane glucose transport but no detectable ER uptake, probably because of lack of a sufficient sodium gradient across the ER membrane. In conclusion, we demonstrate that GLUTs are sufficient for mediating ER glucose transport en route to the plasma membrane. Because of the low volume of the ER, trace amounts of these uniporters contribute to ER solute import during ER transit, while uniporters and cation-coupled transporters carry out export from the ER, together potentially explaining the low selectivity of ER transport. Expression levels and residence time of transporters in the ER, as well as their coupling mechanisms, could be key determinants of ER permeability.

  12. Lu-Hf isotope systematics of fossil biogenic apatite and their effects on geochronology (United States)

    Herwartz, Daniel; Münker, Carsten; Tütken, Thomas; Hoffmann, J. Elis; Wittke, Andreas; Barbier, Bruno


    Reliable methods for direct dating of biogenic apatite from pre-Pleistocene fossils are currently not available, and recent attempts using the Lu-Hf decay system yielded highly inaccurate ages for both bones and teeth. The geological processes accounting for this poor accuracy of Lu-Hf chronometry are not yet understood. Here we explore Lu-Hf systematics in fossil bones and teeth in detail, by applying five different sample digestion techniques that are tested on bones and composites of bone and sediment. Our current dataset implies that dissolution methods only slightly affect the resulting Lu-Hf ages, while clear differences between the individual digestion techniques became apparent for element concentrations. By analysing the insoluble leftovers from incomplete sample dissolution, four main reservoirs of Hf in fossil bones were identified: (1) a radiogenic end-member associated with apatite; (2) an unradiogenic end-member represented by the authigenic minerals or the embedding sediment; (3) a highly unradiogenic end-member that can be attributed to detrital zircon; and (4) a moderately soluble phase (probably a Zr(Hf)-phosphate) that yielded very low Lu/Hf but a highly radiogenic Hf isotope composition at the same time. This Zr(Hf)-phase must have been precipitated within the fossil bone sample at a late stage of burial history, thereby incorporating radiogenic 176Hf released from apatite surfaces over geological timescales. A second focus of our study is the effect of different sediment matrices and of crystal size on the preservation of pristine Lu-Hf isotope compositions in bioapatite. Because near-depositional Lu-Hf ages of phosphate fossils have previously been reported for the London Clay (England) and a calcareous marl from Tendaguru (Tanzania), we herein investigate specimens fossilised in carbonate matrices (calcareous marl from Oker, Germany; carbonate concretions from the Santana Formation, Brazil; carbonate from the Eifel, Germany) and argillaceous

  13. A novel {sup 177}Lu-labeled porphyrin for possible use in targeted tumor therapy

    Energy Technology Data Exchange (ETDEWEB)

    Das, Tapas, E-mail: [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai-400085 (India); Chakraborty, Sudipta [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai-400085 (India); Sarma, Haladhar Dev [Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, Mumbai-400085 (India); Banerjee, Sharmila; Venakatesh, Meera [Radiopharmaceuticals Division, Bhabha Atomic Research Centre, Mumbai-400085 (India)


    Introduction: Porphyrin and its derivatives exhibit inherent affinity for localization in tumors. Hence, porphyrin derivatives radiolabeled with suitable therapeutic radionuclides could be envisaged as potential agents for targeted tumor therapy. In this direction, a water-soluble porphyrin derivative, viz., 5,10,15,20-tetrakis[4-carboxymethyleneoxyphenyl]porphyrin was synthesized in-house and radiolabeled with {sup 177}Lu with an aim to prepare an agent for targeted tumor therapy. {sup 177}Lu is an attractive radionuclide for the development of targeted radiotherapeutic agents owing to its suitable decay characteristics [T{sub 1/2}=6.73 d, E{sub {beta}(max)}=0.49 MeV, E{gamma}=208 keV (11%)], comparatively longer half-life and ease of production with high specific activity. Methods: {sup 177}Lu was produced by irradiation of enriched Lu{sub 2}O{sub 3} (64.3% {sup 176}Lu) at a thermal neutron flux of 1x10{sup 14} n/cm{sup 2}.s for 14 d. The porphyrin was coupled to a suitable chelator, namely, p-aminobenzyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid for complexation with {sup 177}Lu. The radiolabeling was achieved by incubating 50 {mu}g of the conjugate with {sup 177}LuCl{sub 3} (200 ng Lu) in acetate buffer (pH {approx}5) at 50{sup o}C for 1 h. The radiolabeled conjugate was characterized by high-performance liquid chromatography and its biological efficacy was studied in Swiss mice bearing fibrosarcoma tumors. Results: {sup 177}Lu was obtained with a specific activity of {approx}550 TBq/g and radionuclidic purity of 99.98%. The {sup 177}Lu-labeled porphyrin conjugate was obtained with 99% radiochemical purity and it exhibited good in vitro stability. Biodistribution studies revealed good tumor uptake (2.01% IA/g) within 3 h post injection (p.i.) with >94% injected activity exhibiting renal clearance. No significant accumulation of activity was observed in any of the vital organs/tissue. The tumor/blood and tumor/muscle ratios were 2.89 and 16

  14. Meteorite zircon constraints on the bulk Lu-Hf isotope composition and early differentiation of the Earth. (United States)

    Iizuka, Tsuyoshi; Yamaguchi, Takao; Hibiya, Yuki; Amelin, Yuri


    Knowledge of planetary differentiation is crucial for understanding the chemical and thermal evolution of terrestrial planets. The (176)Lu-(176)Hf radioactive decay system has been widely used to constrain the timescales and mechanisms of silicate differentiation on Earth, but the data interpretation requires accurate estimation of Hf isotope evolution of the bulk Earth. Because both Lu and Hf are refractory lithophile elements, the isotope evolution can be potentially extrapolated from the present-day (176)Hf/(177)Hf and (176)Lu/(177)Hf in undifferentiated chondrite meteorites. However, these ratios in chondrites are highly variable due to the metamorphic redistribution of Lu and Hf, making it difficult to ascertain the correct reference values for the bulk Earth. In addition, it has been proposed that chondrites contain excess (176)Hf due to the accelerated decay of (176)Lu resulting from photoexcitation to a short-lived isomer. If so, the paradigm of a chondritic Earth would be invalid for the Lu-Hf system. Herein we report the first, to our knowledge, high-precision Lu-Hf isotope analysis of meteorite crystalline zircon, a mineral that is resistant to metamorphism and has low Lu/Hf. We use the meteorite zircon data to define the Solar System initial (176)Hf/(177)Hf (0.279781 ± 0.000018) and further to identify pristine chondrites that contain no excess (176)Hf and accurately represent the Lu-Hf system of the bulk Earth ((176)Hf/(177)Hf = 0.282793 ± 0.000011; (176)Lu/(177)Hf = 0.0338 ± 0.0001). Our results provide firm evidence that the most primitive Hf in terrestrial zircon reflects the development of a chemically enriched silicate reservoir on Earth as far back as 4.5 billion years ago.



    Štechová, Eva


    Od prvotného nápadu, cez rešerš a porovnávanie s batohmi s rozkladacou funkciou (tele, usárna) a s batohmi spojenými s urban a streetwear módou som sa dopracovala k návrhu, ktorý okrem praktického funkčného dizajnu otvára otázky osobného priestoru vs. verejného priestoru, pracuje s otázkou životného štýlu ako východiskového bodu marketingu a apeluje na mladých ľudí, ktorí trávia čas v mestskom verejnom priestore a svojim spôsobom ho okupujú. Technické parametre batohu vychádzajú z jeho funkčn...

  16. Sex-Dependent Effects of HO-1 Deletion from Adipocytes in Mice. (United States)

    Hosick, Peter A; Weeks, Mary Frances; Hankins, Michael W; Moore, Kyle H; Stec, David E


    Induction of heme oxygenase-1 (HO-1) has been demonstrated to decrease body weight and improve insulin sensitivity in several models of obesity in rodents. To further study the role of HO-1 in adipose tissue, we created an adipose-specific HO-1 knockout mouse model. Male and female mice were fed either a control or a high-fat diet for 30 weeks. Body weights were measured weekly and body composition, fasting blood glucose and insulin levels were determined every six weeks. Adipocyte-specific knockout of HO-1 had no significant effect on body weight in mice fed a high-fat diet but increased body weight in female mice fed a normal-fat diet. Although body weights were not different in females fed a high fat diet, loss of HO-1 in adipocytes resulted in significant alterations in body composition. Adipose-specific HO-1 knockout resulted in increased fasting hyperglycemia and insulinemia in female but not male mice on both diets. Adipose-specific knockout of HO-1 resulted in a significant loss of HO activity and a decrease in the protein levels of adiponectin in adipose tissue. These results demonstrate that loss of HO-1 in adipocytes has greater effects on body fat and fasting hyperglycemia in a sex-dependent fashion and that expression of HO-1 in adipose tissue may have a greater protective role in females as compared to males.

  17. Problematika elektronického obchodu společnosti


    Frolichová, Klára


    Diplomová práce je zaměřena na problematiku zřízení elektronického obchodu společnosti. Obsahem diplomové práce je podrobná analýza trhu a možných dodavatelů řešení, dále jsou řešeny otázky bezpečnosti, práva a technologie. Součástí práce je návrh postupu zavádění internetového obchodu do firmy. Práce se zabývá také internetovým marketingem a SEO optimalizací. The thesis is focused on the establishment of company's e-commerce. Content of the thesis is a detailed market analysis and possibl...

  18. Ordet er dit DR P1

    DEFF Research Database (Denmark)


    Har du brug for en lokal bank? Vestjysk Bank kæmper for livet. Mandag afleverede banken en genopretningsplan til Finanstilsynet, som nu skal beslutte, om man tror, den Lemvig-baserede bank er i stand til at overleve...

  19. ER Consolidated Quarterly Report October 2014

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, John R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    This Environmental Restoration Operations (ER) Consolidated Quarterly Report (ER Quarterly Report) provides the status of ongoing corrective actions and related Long- Term Stewardship (LTS) activities being implemented by Sandia National Laboratories, New Mexico (SNL/NM) ER for the April, May, and June 2014 quarterly reporting period. Section 2.0 provides the status of ER Operations activities including closure activities for the Mixed Waste Landfill (MWL), project management and site closure, and hydrogeologic characterizations. Section 3.0 provides the status of LTS activities that relate to the Chemical Waste Landfill (CWL) and the associated Corrective Action Management Unit (CAMU). Section 4.0 provides the references noted in Section I of this report.

  20. Identical gamma-vibrational bands in {sup 165}Ho

    Energy Technology Data Exchange (ETDEWEB)

    Radford, D.C.; Galindo-Uribarri, A.; Janzen, V.P. [Chalk River Labs., Ontario (Canada)] [and others


    The structure of {sup 165}Ho at moderate spins has been investigated by means of Coulomb excitation. Two {gamma}-vibrational bands (K{sup {pi}} = 11/2{sup {minus}} and K{sup {pi}} = 3/2{sup {minus}}) are observed, with very nearly identical in-band {gamma}-ray energies. Gamma-ray branching ratios are analyzed to extract information on Coriolis mixing, and the role of the K quantum number in identical bands is discussed.

  1. Hvilke Dødehavstekster er "sekteriske"?

    DEFF Research Database (Denmark)

    Holst, Søren


    Skønt Dødehavsrullerne antageligt tilhørte en gruppering, der boede i Qumran, tyder alt på, at mange af teksterne er forfattet andre steder. Artiklen undersøger den særlige sprogbrug, som antageligt er typisk for Qumran-samfundet, og som præger forbavsende få af tekserne. En meget stor del af tek...

  2. Er dansk kornkvalitet rent til rotterne?

    DEFF Research Database (Denmark)

    Dubgaard, Alex


    Målinger viser, at der har været et vist fald i kornets indhold af protein, men de påståede negative konsekvenser er stærkt overdrevne. Påstanden om at dansk korn er så ringe, at byggerier og brødproducenter må hente deres varer i udlandet, holder ikke stik....

  3. Trump er godt nyt for verdensfreden

    DEFF Research Database (Denmark)

    Jakobsen, Peter Viggo


    Trumps uberegnelighed øger ikke risikoen for krig. Den mindsker den ved at få de allierede til at gøre mere og modstanderne til at forhandle. Det er godt for verdensfreden......Trumps uberegnelighed øger ikke risikoen for krig. Den mindsker den ved at få de allierede til at gøre mere og modstanderne til at forhandle. Det er godt for verdensfreden...

  4. Håndbold er en praksis!

    DEFF Research Database (Denmark)

    Olsen, Poul Bitsch


    Dansk håndbold er en kæmpemæssig succeshistorie. Ser man snævert på den udvikling, elitedelen af sporten har gennemlevet de seneste 15 år, viser stort set alle tænkelige parametre fremgang. De internationale resultater for lands og klubhold er med få udfald blevet stadigt bedre, omsætningen i klu...

  5. Arctigenin alleviates ER stress via activating AMPK (United States)

    Gu, Yuan; Sun, Xiao-xiao; Ye, Ji-ming; He, Li; Yan, Shou-sheng; Zhang, Hao-hao; Hu, Li-hong; Yuan, Jun-ying; Yu, Qiang


    Aim: To investigate the protective effects of arctigenin (ATG), a phenylpropanoid dibenzylbutyrolactone lignan from Arctium lappa L (Compositae), against ER stress in vitro and the underlying mechanisms. Methods: A cell-based screening assay for ER stress regulators was established. Cell viability was measured using MTT assay. PCR and Western blotting were used to analyze gene and protein expression. Silencing of the CaMKKβ, LKB1, and AMPKα1 genes was achieved by RNA interference (RNAi). An ATP bioluminescent assay kit was employed to measure the intracellular ATP levels. Results: ATG (2.5, 5 and 10 μmol/L) inhibited cell death and unfolded protein response (UPR) in a concentration-dependent manner in cells treated with the ER stress inducer brefeldin A (100 nmol/L). ATG (1, 5 and 10 μmol/L) significantly attenuated protein synthesis in cells through inhibiting mTOR-p70S6K signaling and eEF2 activity, which were partially reversed by silencing AMPKα1 with RNAi. ATG (1-50 μmol/L) reduced intracellular ATP level and activated AMPK through inhibiting complex I-mediated respiration. Pretreatment of cells with the AMPK inhibitor compound C (25 μmol/L) rescued the inhibitory effects of ATG on ER stress. Furthermore, ATG (2.5 and 5 μmol/L) efficiently activated AMPK and reduced the ER stress and cell death induced by palmitate (2 mmol/L) in INS-1 β cells. Conclusion: ATG is an effective ER stress alleviator, which protects cells against ER stress through activating AMPK, thus attenuating protein translation and reducing ER load. PMID:22705729

  6. Hvad litteraturen kan, er ofte det rigtige ..

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe; Kühn, Lisbet


    Læsning i dansk handler i første omgang om at blive god til at læse, men på mellemtrinnet er det ved at være tiden til også at bruge skønlitteraturen til det, den er god til, nemlig til at få indsigt i menneskelivets kompleksitet. I dette kapitel anbefales det at gøre noget med litteraturen, fx f...

  7. Snip snap snude - dobbelthagerne er ude

    DEFF Research Database (Denmark)

    Larsen, Malene Charlotte; Kofoed, Jette


    Det handler om at være grim. Det står i skarp kontrast til det pæne og polerede på Instagram. Det er flygtigt, useriøst og ligegyldigt. Og så forsvinder det heldigvis igen, så man behøver kun at forholde sig til det i de få sekunder, det foregår. Snapchat vokser i popularitet og er nu det...

  8. Characterization of the ER-Targeted Low Affinity Ca2+ Probe D4ER

    Directory of Open Access Journals (Sweden)

    Elisa Greotti


    Full Text Available Calcium ion (Ca2+ is a ubiquitous intracellular messenger and changes in its concentration impact on nearly every aspect of cell life. Endoplasmic reticulum (ER represents the major intracellular Ca2+ store and the free Ca2+ concentration ([Ca2+] within its lumen ([Ca2+]ER can reach levels higher than 1 mM. Several genetically-encoded ER-targeted Ca2+ sensors have been developed over the last years. However, most of them are non-ratiometric and, thus, their signal is difficult to calibrate in live cells and is affected by shifts in the focal plane and artifactual movements of the sample. On the other hand, existing ratiometric Ca2+ probes are plagued by different drawbacks, such as a double dissociation constant (Kd for Ca2+, low dynamic range, and an affinity for the cation that is too high for the levels of [Ca2+] in the ER lumen. Here, we report the characterization of a recently generated ER-targeted, Förster resonance energy transfer (FRET-based, Cameleon probe, named D4ER, characterized by suitable Ca2+ affinity and dynamic range for monitoring [Ca2+] variations within the ER. As an example, resting [Ca2+]ER have been evaluated in a known paradigm of altered ER Ca2+ homeostasis, i.e., in cells expressing a mutated form of the familial Alzheimer’s Disease-linked protein Presenilin 2 (PS2. The lower Ca2+ affinity of the D4ER probe, compared to that of the previously generated D1ER, allowed the detection of a conspicuous, more clear-cut, reduction in ER Ca2+ content in cells expressing mutated PS2, compared to controls.

  9. High efficiency laser action in mildly doped Yb:LuYAG ceramics

    Czech Academy of Sciences Publication Activity Database

    Pirri, A.; Toci, G.; Li, J.; Xie, T.; Pan, Y.; Babin, Vladimir; Beitlerová, Alena; Nikl, Martin; Vannini, M.


    Roč. 73, Nov (2017), s. 312-318 ISSN 0925-3467 Institutional support: RVO:68378271 Keywords : laser ceramics * Yb laser * mixed garnets * LuYAG Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 2.238, year: 2016

  10. Pretargeted 177Lu radioimmunotherapy of carcinoembryonic antigen-expressing human colonic tumors in mice.

    NARCIS (Netherlands)

    Schoffelen, R.; Graaf, W.T.A. van der; Franssen, G.M.; Sharkey, R.M.; Goldenberg, D.M.; McBride, W.J.; Rossi, E.A.; Eek, A.; Oyen, W.J.G.; Boerman, O.C.


    Pretargeted radioimmunotherapy (PRIT) with bispecific antibodies in combination with a radiolabeled peptide reduces the radiation dose to normal tissues, especially the bone marrow. In this study, the optimization, therapeutic efficacy, and toxicity of PRIT of colon cancer with a (177)Lu-labeled

  11. Unustagem kõvaketas, kasutagem operatiivmälu! / Katrin Ruus

    Index Scriptorium Estoniae

    Ruus, Katrin


    Valik Mart Viljuse, Katrin Teesi, Piret Räni, Reimo Võsa-Tangsoo, Merle ja Erki Kannuse ning rühmituste Puhas Rõõm ja Infotankistid viimaste aastate töödest näituseprojektina "Operatiivmälu" Pärnu Kunstnike Maja galeriis ja Pärnu Linnagaleriis. 11 ill

  12. Measurement of 173Lu(n,γ) Cross Sections at DANCE (United States)

    Roig, O.; Theroine, C.; Ebran, A.; Méot, V.; Bond, E. M.; Bredeweg, T. A.; Couture, A.; Haight, R. C.; Jandel, M.; Nortier, F. M.; O'Donnell, J. M.; Rundberg, R. S.; Taylor, W. A.; Ullmann, J. L.; Vieira, D. J.


    A highly gamma-radioactive target, 3.7 GBq, of 173Lu isotope was placed inside the DANCE array (Detector for Advanced Neutron Capture Experiments) at Los Alamos to study the radiative neutron capture on an unstable isotope. The 173Lu element was produced by naturalHf(p,xn) reactions following by beta-decays at the Isotope Production Facility (IPF). Measurements of radiative neutron capture cross section on 173Lu were achieved at the Los Alamos Neutron Science Center (LANSCE) spallation neutron source facility over the neutron energy range from thermal up to 1 keV. A special configuration was necessary to perform the experiment using the DANCE [1] array due to the high gamma activity of the target. We will report on the target production, the experiment and the results obtained for the radiative neutron capture on 173Lu. The radiative capture cross section was obtained for the first time on this unstable nucleus. Some resonances have been characterized. A comparison with a recent data evaluation is presented.

  13. Intrinsic gK factors of odd-mass 167− 179Lu isotopes

    Indian Academy of Sciences (India)

    In this paper, g K -factors of the intrinsic magnetic moments and effective spin gyromagnetic factors ( g s eff ) of the 167−179Lu isotopes have been studied within the Tamm–Dancoff approximation (TDA) (Kuliev et al, Sov. J. Nucl. Phys. 9, 185 (1969)) by using a realistic potential such as Woods–Saxon potential for the first ...

  14. Luminescence of Eu3+ rare-earth ions in Lu2O3 nanospheres (United States)

    Zaitsev, S. V.; Gruzintsev, A. N.; Yermolayeva, Yu. V.; Matveevskaya, N. A.; Zverkova, I. I.; Emelchenko, G. A.; Tolmachev, A. V.


    The kinetics of luminescence of Eu3+ ions in Lu2O3:Eu nanospheres with diameters of 100-270 nm and a small standard deviation of the size distribution mode accelerating spontaneous luminescence, which is confirmed by the calculation of ranges of existence of whispering-gallery modes in studied nanospheres.

  15. LU Factorization with Partial Pivoting for a Multi-CPU, Multi-GPU Shared Memory System

    Energy Technology Data Exchange (ETDEWEB)

    Kurzak, Jakub [Univ. of Tennessee, Knoxville, TN (United States); Luszczek, Pitior [Univ. of Tennessee, Knoxville, TN (United States); Faverge, Mathieu [Univ. of Tennessee, Knoxville, TN (United States); Dongarra, Jack [Univ. of Tennessee, Knoxville, TN (United States); Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Univ. of Manchester (United Kingdom)


    LU factorization with partial pivoting is a canonical numerical procedure and the main component of the High Performance LINPACK benchmark. This article presents an implementation of the algorithm for a hybrid, shared memory, system with standard CPU cores and GPU accelerators. Performance in excess of one TeraFLOPS is achieved using four AMD Magny Cours CPUs and four NVIDIA Fermi GPUs.

  16. Hüsteeria, seks ja selektiivne mälu / Anneli Porri

    Index Scriptorium Estoniae

    Porri, Anneli, 1980-


    Marge Monko näitus "Uurimusi kodanlusest" (Charcot' klassifitseeritud krambiasendeid esitab tantsija Krõõt Juurak) Hobusepea galeriis 17.-22. V; Jane Suviste ja Piibe Piirma näitus "Editeeritud mälu" Tallinna Linnagaleriis kuni 28. V; Andres Lõo kureeritud noortenäitus "Sex" Vaal-galeriis 2.-20. V

  17. Weak antilocalization effect and noncentrosymmetric superconductivity in a topologically nontrivial semimetal LuPdBi

    KAUST Repository

    Xu, Guizhou


    A large number of half-Heusler compounds have been recently proposed as three-dimensional (3D) topological insulators (TIs) with tunable physical properties. However, no transport measurements associated with the topological surface states have been observed in these half-Heusler candidates due to the dominating contribution from bulk electrical conductance. Here we show that, by reducing the mobility of bulk carriers, a two-dimensional (2D) weak antilocalization (WAL) effect, one of the hallmarks of topological surface states, was experimentally revealed from the tilted magnetic field dependence of magnetoconductance in a topologically nontrivial semimetal LuPdBi. Besides the observation of a 2D WAL effect, a superconducting transition was revealed at T c ∼ 1.7â.K in the same bulk LuPdBi. Quantitative analysis within the framework of a generalized BCS theory leads to the conclusion that the noncentrosymmetric superconductivity of LuPdBi is fully gapped with a possibly unconventional pairing character. The co-existence of superconductivity and the transport signature of topological surface states in the same bulk alloy suggests that LuPdBi represents a very promising candidate as a topological superconductor.

  18. lu olemuse jälile juhatas meritigu / Tiit Kändler

    Index Scriptorium Estoniae

    Kändler, Tiit, 1948-


    Columbia ülikooli teadlane, tänavuse Nobeli meditsiini- ja füsioloogiapreemia saanud Eric Kandel uuris aplüüsia toel välja, kuidas aju asju mäletab. Skeem : Mälu põhineb keemiliste muutuste säilitamisel

  19. New system for production of reactor medical radionuclides tested with Lu-176

    Czech Academy of Sciences Publication Activity Database

    Seifert, Daniel; Kropáček, Martin; Tomeš, Marek; Kučera, Jan; Lebeda, Ondřej


    Roč. 42, S (2015), s. 857-857 ISSN 1619-7070. [28th Annual congress of the European-Association-of-Nuclear-Medicine (EANM). 10.10.2015-14.10.2015, Hamburg] R&D Projects: GA MŠk(CZ) LM2011019 Institutional support: RVO:61389005 Keywords : Lu-177 * radionuclides * reactor Subject RIV: BG - Nuclear, Atomic and Molecular Physics, Colliders

  20. Lu et al., Afr J Tradit Complement Altern Med. (2013) 10(4):83-87 ...

    African Journals Online (AJOL)


    Lu et al., Afr J Tradit Complement Altern Med. (2013) ... manifestation was skin and accessory damage; nervous system and gastrointestinal system damage were also easier to find, and the .... accessory, and the digestive system, or that allergic reactions, gastrointestinal reactions, fever and other symptoms are easy to.

  1. Scintillation Properties of Praseodymium Activated Lu3Al5O12 Single Crystals

    NARCIS (Netherlands)

    Drozdowski, W.; Dorenbos, P.; De Haas, J.T.M.; Drozdowska, R.; Owens, A.; Kamada, K.; Tsutsumi, K.; Usuki, Y.; Yanagida, T.; Yoshikawa, A.


    Scintillation properties of LuAG:Pr grown by Furukawa Co. Ltd., Japan, have been studied. The best crystals display light outputs up to 19000 ph/MeV and an energy resolution of 4.6% at 662 keV. The scintillation yield is found to be a function of size and temperature of the sample; it can be

  2. Spectroscopic investigations on Ho 3+ doped mixed alkali phosphate glasses (United States)

    Ratnakaram, Y. C.; Srihari, N. V.; Naidu, D. Thirupathi; Vijayakumar, A.; Chakradhar, R. P. S.


    Optical absorption and emission properties of Ho3+ doped mixed alkali phosphate glasses of the type 69.5NH4H2PO4 · xLi2CO3 · (30 - x)K2CO3 and 69.5NH4H2PO4 · xNa2CO3 · (30 - x)K2CO3 (where x = 5, 10, 15, 20 and 25) were studied. Racah (E1, E2, E3), spin-orbit (ξ4f) and configuration interaction (α, β) parameters are calculated and these values are compared for different x values in the glass matrix. Judd-Ofelt intensity parameters (Ω2, Ω4, Ω6) are calculated for all the Ho3+ doped mixed alkali phosphate glasses. From these parameters and from the spectral profiles of the hypersensitive transition structural studies have obtained. Radiative transition probabilities (A), radiative lifetimes (τ), branching ratios (β) and integrated absorption cross-sections (Σ) are obtained from the intensity parameters. Emission cross-sections (σ) are calculated for the two transitions, 5F4, 5S2 → 5I8 and 5F5 → 5I8 of Ho3+ in these two mixed alkali phosphate glasses. Optical band gaps (Eopt) for both direct and indirect transitions are reported.

  3. Design městského elektrokola


    Sojka, Vojtěch


    Předmětem této diplomové práce je design asistovaného městského elektrokola – tzv. pedelec. Cílem bylo navrhnout takový design, který bude splňovat jak požadavky zadavatele práce, tak kritéria nadčasového designu za použití moderních materiálů a technologií. Výsledkem je návrh, který ve srovnání s běžně prodávanými elektrokoly, vyniká především výrazně lepším rozložením hmotnosti a uživatelským komfortem. Práce je řešena po designérské, technické, ergonomické, psychologické a také ekonomické ...

  4. In Vitro comparison of 213Bi- and 177Lu-radiation for peptide receptor radionuclide therapy. (United States)

    Chan, Ho Sze; de Blois, Erik; Morgenstern, Alfred; Bruchertseifer, Frank; de Jong, Marion; Breeman, Wouter; Konijnenberg, Mark


    Absorbed doses for α-emitters are different from those for β-emitters, as the high linear energy transfer (LET) nature of α-particles results in a very dense energy deposition over a relatively short path length near the point of emission. This highly localized and therefore high energy deposition can lead to enhanced cell-killing effects at absorbed doses that are non-lethal in low-LET type of exposure. Affinities of DOTA-DPhe1-Tyr3-octreotate (DOTATATE), 115In-DOTATATE, 175Lu-DOTATATE and 209Bi-DOTATATE were determined in the K562-SST2 cell line. Two other cell lines were used for radiation response assessment; BON and CA20948, with a low and high expression of somatostatin receptors, respectively. Cellular uptake kinetics of 111In-DOTATATE were determined in CA20948 cells. CA20948 and BON were irradiated with 137Cs, 177Lu-DTPA, 177Lu-DOTATATE, 213Bi-DTPA and 213Bi-DOTATATE. Absorbed doses were calculated using the MIRDcell dosimetry method for the specific binding and a Monte Carlo model of a cylindrical 6-well plate geometry for the exposure by the radioactive incubation medium. Absorbed doses were compared to conventional irradiation of cells with 137Cs and the relative biological effect (RBE) at 10% survival was calculated. IC50 of (labelled) DOTATATE was in the nM range. Absorbed doses up to 7 Gy were obtained by 5.2 MBq 213Bi-DOTATATE, in majority the dose was caused by α-particle radiation. Cellular internalization determined with 111In-DOTATATE showed a linear relation with incubation time. Cell survival after exposure of 213Bi-DTPA and 213Bi-DOTATATE to BON or CA20948 cells showed a linear-exponential relation with the absorbed dose, confirming the high LET character of 213Bi. The survival of CA20948 after exposure to 177Lu-DOTATATE and the reference 137Cs irradiation showed the typical curvature of the linear-quadratic model. 10% Cell survival of CA20948 was reached at 3 Gy with 213Bi-DOTATATE, a factor 6 lower than the 18 Gy found for 177Lu

  5. 177Lu-labeled RGD-BBN heterodimeric peptide for targeting prostate carcinoma. (United States)

    Jiang, Lei; Miao, Zheng; Liu, Hongguang; Ren, Gang; Bao, Ande; Cutler, Cathy S; Shi, Hongcheng; Cheng, Zhen


    Radiolabeled Arg-Gly-Asp (RGD) and bombesin (BBN) heterodimers have been investigated for dual targeting of tumor integrin αvβ3 receptors and gastrin-releasing peptide receptors. The goal of this study was to evaluate the potential use of a Lu-labeled RGD-BBN heterodimer for targeted prostate cancer therapy. A 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-conjugated RGD-BBN peptide (DO3A-RGD-BBN) was radiolabeled with Lu and purified by high-performance liquid chromatography. The in-vivo biodistribution study of Lu-DO3A-RGD-BBN was carried out in mice bearing human prostate cancer PC3 xenografts. The receptor-targeting specificity of the radiolabeled peptide was assayed by injecting the tracer with the unlabeled RGD-BBN peptide. Radiation absorbed doses in adult male patients, based on biodistribution data from mice, were also calculated. DO3A-RGD-BBN peptides were successfully labeled with Lu, and high radiochemical purity (>95%) could be achieved after high-performance liquid chromatography purification. In human PC3 xenograft-bearing mice, the tumor accumulation of Lu-DO3A-RGD-BBN was 5.88±1.12, 2.77±0.30, 2.04±0.19, and 1.18±0.19%ID/g at 0.5, 2, 24, and 48 h, respectively. With rapid clearance from normal tissues, the radiolabeled probe displayed high tumor-to-blood and tumor-to-muscle ratios. On calculating the radiation absorbed doses for Lu-DO3A-RGD-BBN, we found that the prostate tumor and the pancreas were the organs receiving the highest radiation absorbed doses. Dual integrin αvβ3 and GPRP-targeted agent Lu-DO3A-RGD-BBN shows excellent prostate cancer-targeting ability, and it is worthy of further evaluation for prostate cancer-targeted therapy.

  6. Ab initio thermal rate calculations of HO + HO = O(3P) + H2O reaction and isotopologues. (United States)

    Nguyen, Thanh Lam; Stanton, John F


    The forward and reverse reactions, HO + HO ⇌ O((3)P) + H2O, which play roles in both combustion and laboratory studies, were theoretically characterized with a master equation approach to compute thermal reaction rate constants at both the low and high pressure limits. Our ab initio k(T) results for the title reaction and two isotopic variants agree very well with experiments (within 15%) over a wide temperature range. The calculated reaction rate shows a distinctly non-Arrhenius behavior and a strong curvature consistent with the experiment. This characteristic behavior is due to effects of positive barrier height and quantum mechanical tunneling. Tunneling is very important and contributes more than 70% of total reaction rate at room temperature. A prereactive complex is also important in the overall reaction scheme.

  7. Glass and mineral chemistry of northern central Indian ridge basalts: Compositional diversity and petrogenetic significance

    Digital Repository Service at National Institute of Oceanography (India)

    Ray, Dwijesh; Banerjee, R.; Iyer, S.D.; Basavalingu, B.; Mukhopadhyay, S.

    ) 6 Y (10 ) 6 Mg# Ba Rb Th U NbLa Ce Sr Nd Sm Zr Hf Eu Ti Dy YYb LuTb La Ce Pr Nd Sm Eu Gd Tb Dy Ho Er Yb Lu 1 10 100 (a) (b) 1 10 100 Rock/chondrite PMN/ormalised Di Ol Opx Qz 20 kbar 15 kbar 10 kbar 1 bar ol ol opx au ol opx ol opx au au opx ...

  8. Návrh a optimalizace sacího a výfukového potrubí zážehového motoru


    Chuchma, Ondřej


    Diplomová práce je zaměřena na konstrukční návrh a optimalizaci sacího a výfukového potrubí motoru C20XE. Jedná se čtyřválcový zážehový motor o zdvihovém objemu 2 l, jenž byl vyráběn automobilkou Opel. Tento agregát je určen pro zástavbu do automobilu Opel Astra F, který je stavěn k závodním účelům. Pro optimalizaci rozměrových parametrů je použit software Lotus Engine Simulation, jenž simuluje jednorozměrné proudění plynů v potrubí. 3D CAD modely jsou provedeny v programu Pro ENGINEER. Th...

  9. Zile Elbaşoğlu Camii’nin Sıvalar Altında Kalan Gizemi The Mystery Of The Zile-Elbaşoğlu Mosque Remains Under Plasters

    Directory of Open Access Journals (Sweden)

    Ali Murat AKTEMUR


    örtgen planlı Elbaşoğlu Camii yöredeki ahşap destekli ve ahşap tavanlı cami örneklerinden biridir. 2011 yılına kadar duvarları ve tavanındaki, hatta mihrap, ahşap destek, ahşap sütunce, ahşap mahfil, galeriler yani kısaca caminin tüm ahşap unsurları tatlı-kireç sıva üzerine yağlıboya ile kaplıydı. 2011 yılında çatıdan akan sulardan dolayı yapılan basit onarım sırasında tesadüfen düşen sıva altında kalem-işi süslemeler ve ahşap dekorasyon örneklerinin çıkması üzerine onarım durdurulmuş ardından Vakıflar Genel Müdürlüğü idaresinde yapılan temizlik ve raspa işlemleriyle caminin iç mekanındaki zengin kalem-işi örnekleri, ahşap dekorasyon örnekleri ile sıva altında kalan gizem ortaya çıkarılmıştır.Harim kısmında duvarların üst örtü ile birleştiği noktalar siyah zemin üzerine sülüs-hat ile yazılmış ayet kuşağının yer aldığı bir içbükey bordürle çerçevelenmiştir. Ayet kuşağının üstündeki pervazlarla yükseltilen tavanın köşeleri çıtaların çakılması sonucu oluşturulmuş, üçgen yüzeylere bölünmüş ve böylece ortada sekizgen bir alan oluşturulmuştur. sekizgenin tam ortasında yer alan sekizgen formlu göbek, oyma tekniği ile işlenmiş, barok karakterli bitkisel motiflerle dekore edilmiştir. Tavanın dört köşesinde aşırı plastik bitkisel kabartmaların dekore ettiği üçgen panolar yer alır. Duvarlarda bitkisel motifli kalem-işi süslemeler, mahfil, minber, sütunce gibi ahşap unsurlarda da oyma tekniği ile işlenmiş bitkisel ve geometrik motifler cami içerisinde adeta boş yer kalmamacasına göz alıcı bir zenginlik sunmaktadır.1801 yılında yapılan, Cumhuriyetin ilk yıllarında da yöreye özgü tatlı-kireç sıvayla kapatılıp üstüne boya çekilen bu zengin dekorasyon, Türk ahşap sanatının ve kalem-işi süslemeciliğinin en zengin örneklerini sunmaktadır.

  10. Crystal growth, structure, infrared spectroscopy, and luminescent properties of rare-earth gallium borates RGa3(BO3)4, R = Nd, Sm-Er, Y (United States)

    Borovikova, Elena Yu.; Boldyrev, Kirill N.; Aksenov, Sergey M.; Dobretsova, Elena A.; Kurazhkovskaya, Victoria S.; Leonyuk, Nikolay I.; Savon, Alexander E.; Deyneko, Dina V.; Ksenofontov, Dmitry A.


    Crystals of the rare-earth gallium borates RGa3(BO3)4, where R = Nd, Sm-Er, or Y, were grown by the flux method. The crystal structures of RGa3(BO3)4 (R = Eu, Ho) were studied on the basis of single-crystal X-ray diffraction measurements. The hexagonal unit-cell parameters are a = 9.4657(1) Å, c = 7.4667(1) Å and a = 9.4394(2) Å, c = 7.4322(1) Å for EuGa3(BO3)4 and HoGa3(BO3)4, respectively, space group R32. Structure model was determined by "charge flipping" method and refined to R = 1.93% [EuGa3(BO3)4] and R = 1.89% [HoGa3(BO3)4] in anisotropic approximation. All grown gallium borates were investigated by infrared (IR) spectroscopy technique in a middle and far IR region. IR spectra of rare-earth gallium borates correspond to a pure rhombohedral (R32) polytype structure. Small inclusions of a monoclinic phase were detected only in Eu and Nd compounds. Luminescence of Eu and Ho gallium borates was studied at room temperature. The measured decay times for the most intensive emission lines of EuGa3(BO3)4 (∼614 nm) and HoGa3(BO3)4 (434 nm) are 940 μs and 140 μs, respectively. The scheme of crystal-field energy levels of Eu3+ in EuGa3(BO3)4 was built on the basis of the temperature-dependent optical transmission measurements combined with the luminescence data. The measured UV absorption edge for RGa3(BO3)4 is at about 300 nm.

  11. Implications of iodine chemistry for daytime HO2 levels at Rishiri Island (United States)

    Kanaya, Yugo; Yokouchi, Yoko; Matsumoto, Jun; Nakamura, Kenji; Kato, Shungo; Tanimoto, Hiroshi; Furutani, Hiroshi; Toyota, Kenjiro; Akimoto, Hajime


    The observed midday maximum in the mixing ratio of HO2 at Rishiri Island in June 2000 was ~10 pptv, but photochemical box model simulations overpredicted HO2 at this location by an average of 70%. This overestimation was significant only when the mixing ratio of NO was lower than 300 pptv, and was coincident with overprediction of the NO/NO2 ratio. We detected several organoiodines, presumably emitted from seaweeds, and propose the presence of the IO radical. IO could reduce HO2 mixing ratios via the formation of HOI that may subsequently be scavenged by aerosols or lost by photolysis and may also convert NO to NO2 directly. Model calculations with known iodine chemistry could reproduce the observed HO2 with 12-25 pptv of IO. Although iodine chemistry is unlikely to explain the entire discrepancy in HO2, several pptv of IO could significantly reduce HO2 mixing ratios and NO/NO2 ratios.

  12. Kinetics of the reaction of iodine atoms with HO sub 2 radicals

    Energy Technology Data Exchange (ETDEWEB)

    Jenkin, M.E.; Cox, R.A. (Harwell Laboratory, Oxfordshire (England)); Mellouki, A.; Le Bras, G.; Poulet, G. (CNRS, Orleans (France))


    The rate coefficient (k{sub 7}) for the reaction of iodine atoms with HO{sub 2} radicals, I + HO{sub 2} {yields} HI + O{sub 2}, has been measured directly with use of the discharge-flow/EPR technique, and the molecular-modulation/UV-absorption spectroscopy technique. Discharge-flow measurements were made under pseudo-first-order conditions with iodine atoms in large excess over HO{sub 2}. Molecular-modulation measurements were made with iodine atoms in excess over HO{sub 2}, but the I + HO{sub 2} reaction was occurring in competition with the self-reaction of HO{sub 2}. The potential significance of this reaction as a sink for iodine in the troposphere and other aspects of tropospheric iodine chemistry are considered with a simple model of the atmospheric boundary layer.

  13. Single vial kit formulation of DOTATATE for preparation of (177) Lu-labeled therapeutic radiopharmaceutical at hospital radiopharmacy. (United States)

    Mukherjee, Archana; Lohar, Sharad; Dash, Ashutosh; Sarma, Haladhar Dev; Samuel, Grace; Korde, Aruna


    The clinical applications of radiolabeled somatostatin analogue (177) Lu-DOTA-Tyr(3) -Thr(8) -Octreotide ((177) Lu-DOTATATE) constitute a promising treatment option for patients with disseminated and inoperable neuroendocrine (NET) tumors. Formulation of (177) Lu-DOTATATE in hospital radiopharmacy under aseptic conditions in a safe and reliable manner is a major constraint for its extensive use. The present work was intended to develop a kit for the safe preparation of the therapeutic radiopharmaceutical, viz. (177) Lu-DOTATATE of high quality that can be easily adapted at conventional hospital radiopharmacies. Single vial kits of DOTATATE were formulated and evaluated for suitability for radiolabeling as well as stability on its storage. Patient dose of (177) Lu-DOTATATE (7.4 GBq) could be successfully prepared using semi-automated in-house setup that assures safe handling and high yields of product of pharmaceutical purity suitable for clinical use. Fast clearance of activity via renal route was observed in preclinical biodistribution studies of (177) Lu-DOTATATE carried out in normal Swiss mice. Deployment of in-house produced (177) LuCl3 , cold kits and easy adaptability of synthesis setup at hospital radiopharmacy for preparation is likely to expand applications of peptide receptor radionuclide therapy. Copyright © 2015 John Wiley & Sons, Ltd.

  14. Insights into the photochemical transformation pathways of triclosan and 2′-HO-BDE-28

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Ya-nan; Xie, Qing; Chen, Jingwen, E-mail:; Li, Yingjie; Fu, Zhiqiang


    Highlights: • Direct photolysis of anionic HO-PXDEs occurs through excited singlet states. • Dioxin products are formed from excited singlet states of HO-PXDEs. • Self-sensitized photolysis is involved in the phototransformation of HO-PXDEs. • {sup 1} O{sub 2} and ·OH can be generated in energy or electron transfer reactions between excited HO-PXDEs and dissolved O{sub 2}. - Abstract: Hydroxylated polyhalogenated diphenyl ethers (HO-PXDEs) have been recognized as a group of widely detected emerging contaminants in natural waters. Photolysis was proved to be an important transformation pathway for these compounds and their direct phototransformation results in highly toxic dioxins. However, the roles of excited states and reactive oxygen species in the photochemical transformation of these compounds are still unclear. In this study, 2′-HO-2,4,4′-trichlorodiphenyl ether (triclosan) and 2′-HO-2,4,4′-tribromodiphenyl ether (2′-HO-BDE-28) were selected as model compounds to investigate their phototransformation processes. Results showed that the direct photolysis reactions of both triclosan and 2′-HO-BDE-28 occurred via their respective excited singlet states, leading to the generation of dioxins. In addition, the energy and electron transfer reactions between excited states of model compounds and molecular O{sub 2} can lead to the generation of {sup 1}O{sub 2} and ·OH, which results in self-sensitized photolysis. We also found that both the k, Φ dioxin yield for anionic triclosan were higher than those of anionic 2′-HO-BDE-28. This study revealed the roles of the excited states in direct photolysis and the generation pathway of reactive oxygen species in self-sensitized photolysis of HO-PXDEs, which is important for understanding the phototransformation mechanisms of HO-PXDEs.

  15. Complexes of 4-chlorophenoxyacetates of Nd(III), Gd(III) and Ho(III)


    Ferenc, W.; Bernat, M.; Sarzyński, J.; Głuchowska, H.


    The complexes of 4-chlorophenoxyacetates of Nd(III), Gd(III) and Ho(III) have been synthesized as polycrystalline hydrated solids, and characterized by elemental analysis, spectroscopy, magnetic studies and also by X-ray diffraction and thermogravimetric measurements. The analysed complexes have the following colours: violet for Nd(III), white for Gd(III) and cream for Ho(III) compounds. The carboxylate groups bind as bidentate chelating (Ho) or bridging ligands (Nd, Gd). On heating to 1173K ...

  16. Efterlønnernes helbred er nu ok

    DEFF Research Database (Denmark)

    Jørgensen, Michael; Høgelund, Jan; Brink Thomsen, Lars


    føler, at man har et decideret dårligt helbred eller er nedslidt". Ja, men det er jo ikke ensbetydende med, at man ikke er i stand til at arbejde. Faktisk er der mange med helbredsproblemer, som arbejder: I 2010 var knap halvdelen af de ca. 560.000 personer, som oplyser, at de har et handicap eller...

  17. Nuclear collective states in 110Cd, 192Pt, 192Os and 166Er


    Eid, Elie Said


    The properties of the low-lying energy states of 110Cd, 192Pt, 192Pt and 166Er following the radioactive decays of 110mAg, 192Ir and 166mHo were investigated. Two high resolution Ge(Li) detectors, one intrinsic germanium detector and a Compton suppression system were employed for the measurements of the gamma-ray energies and relative intensities, gamma-gamma coincidence measurements using a conventional fast-slow coincidence technique were performed by coupling the Ge(Li) detectors to a ...

  18. Signature inversion in the semidecoupled {pi}h{sub 9/2} x {nu}i{sub 13/2} band of the odd-odd nucleus {sup 172}Lu

    Energy Technology Data Exchange (ETDEWEB)

    Venkova, Ts [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Institute of Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, BG-1784, Sofia (Bulgaria); Lieder, R.M.; Gast, W.; Lieder, E.O.; Jaeger, H.M.; Mihailescu, L. [Institut fuer Kernphysik, Forschungszentrum Juelich, D-52425, Juelich (Germany); Bazzacco, D.; Menegazzo, R.; Lunardi, S.; Rossi Alvarez, C.; Ur, C.; Martinez, T. [Dipartimento di Fisica dell' Universita and Istituto Nazionale di Fisica Nucleare, Sezione di Padova, I-35131, Padova (Italy); Angelis, G. de; Axiotis, M.; Napoli, D. [Laboratori Nazionali di Legnaro, Istituto Nazionale di Fisica Nucleare, I-35020, Legnaro (Padova) (Italy); Urban, W.; Rzaca-Urban, T. [Institute of Experimental Physics, University of Warsaw, PL-00-681, Warszawa (Poland)


    High-spin states in the odd-odd nucleus {sup 172}Lu have been populated in a {sup 170}Er({sup 7}Li,5n) reaction at 51 MeV and the emitted {gamma}-radiation was detected with the GASP array. A new semidecoupled band with the proposed {pi}1/2{sup -}[541] x {nu}7/2 + [633] configuration has been established exhibiting a signature inversion. A systematic study of the signature inversion in odd-odd nuclei of the rare-earth region is presented. The variation of the inversion spin remains nearly constant for nuclei with the same N-Z, increases with N for an isotopic chain and decreases with Z for an isotonic chain. On the basis of the systematics a change of the spins by 1{Dirac_h} is proposed for the semidecoupled bands in {sup 180}Re, {sup 182,184}Ir and {sup 184,186}Au. (orig.)

  19. Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

    Directory of Open Access Journals (Sweden)

    Seung-Jun Yoo


    Full Text Available BackgroundReperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote DNA strand breaks. As biliverdin and bilirubin produced by heme oxygenase isoform 1 (HO-1 have antioxidant properties, the production of both antioxidants by HO-1 may help increase the resistance of the ischemic brain to oxidative stress. In the present study, the survival effect of HO-1 was confirmed using hemin.MethodsTo confirm the roles of HO-1, carbon monoxide, and cyclic guanosine monophosphate further in the antioxidant effect of HO-1 and bilirubin, cells were treated with cycloheximide, desferoxamine, and zinc deuteroporphyrin IX 2,4 bis glycol, respectively.ResultsHO-1 itself acted as an antioxidant. Furthermore, iron, rather than carbon monoxide, was involved in the HO-1-mediated survival effect. HO-1 activity was also important in providing bilirubin as an antioxidant.ConclusionOur results suggested that HO-1 helped to increase the resistance of the ischemic brain to oxidative stress.

  20. [hHO-1 structure prediction and its mutant construct, expression, purification and activity analysis]. (United States)

    Xia, Zhen Wei; Cui, Wen Jun; Zhou, Wen Pu; Zhang, Xue Hong; Shen, Qing Xiang; Li, Yun Zhu; Yu, Shan Chang


    Human Heme Oxygenase-1 (hHO-1) is the rate-limiting enzyme in the catabolism reaction of heme, which directly regulates the concentration of bilirubin in human body. The mutant structure was simulated by Swiss-pdbviewer procedure, which showed that the structure of active pocket was changed distinctly after Ala25 substituted for His25 in active domain, but the mutated enzyme still binded with heme. On the basis of the results, the expression vectors, pBHO-1 and pBHO-1(M), were constructed, induced by IPTG and expressed in E. coli DH5alpha strain. The expression products were purified with 30%-60% saturation (NH4)2SO4 and Q-Sepharose Fast Flow column chromatography. The concentration of hHO-1 in 30%-60% saturation (NH4)2SO4 components and in fractions through twice column chromatography was 3.6-fold and 30-fold higher than that in initial product, respectively. The activity of wild hHO-1 (whHO-1) and mutant hHO-1 (deltahHO-1) showed that the activity of deltahHO-1 was reduced 91.21% compared with that of whHO-1. The study shows that His25 is of importance for the mechanism of hHO-1, and provides the possibility for effectively regulating the activity to exert biological function.



    Castrillejo, Yolanda; Oduber, Fernanda; Barrado, Enrique


    The electrode reaction of Ho(III)/Ho couple in the eutectic LiCl-KCl, at Cd liquid electrodes (i.e a Cd pool and a Cd coated W electrodes) was investigated in the temperature range of 673-823K. In both electrodes, the electrochemical reduction of Ho(III) was observed at less cathodic potential values than at the surface of an inert W electrode, due to the decrease of Ho activity in the metal phase. Junta de Castilla y León Proyecto VA171U14

  2. Model elektronického obchodu pro služby


    Zechmeisterová, Věra


    Obsahem práce je vytvoření modelu informačního zabezpečení služeb autoopravny a vytvoření odpovídajícího systémového řešení elektronického obchodování této autoopravny. The content of this Master thesis is the creation of the car repair shop services informational security model and also the creation of commensurate e-commerce system solution for this car repair shop. A

  3. Development of 166Ho-zoledronate as a bone marrow ablative agent

    Directory of Open Access Journals (Sweden)

    Mirsaeed Nikzad


    Full Text Available In this study, production, quality control and biodistribution studies of 166Ho-zoledronate have been presented as a possible bone marrow ablative agent. Ho-166 chloride was produced by thermal neutron irradiation of natural 165Ho(NO33 samples. 166Ho-zoledronate complex was prepared by adding the desired amount of zoledronate solution (0.2 mL, 150 mg/ml in 1 M NaOH to appropriate amount of the 166HoCl3 solution.  Radiochemical purity of the complex was monitored by instant thin layer chromatography (ITLC. Stability studies of the complex in the final preparation and in the presence of human serum were performed up to 48 h. The biodistribution of 166Ho-zoledronate and 166HoCl3 in wild-type mice was checked up to 72 h. 166Ho-zoledronate complex was prepared in high radiochemical purity (> 99%, ITLC and specific activity of 4.4 GBq/mmol. The major accumulation of radiolabelled complex was observed in the bone tissue. These findings suggest 166Ho-zoledronatehas can be a possible candidate for bone marrow ablation in patients with multiple myeloma.

  4. Composition and local bonding in RE-Si-M-O-N (M=Mg, Al ; RE=La, Lu) glasses

    Energy Technology Data Exchange (ETDEWEB)

    Fouquet-Parry, V. [Service de Physique et de Chimie des Surfaces et des Interfaces, DSM/DRECAM/SPCSI, CEA Saclay, 91191 Gif sur Yvette Cedex (France); Paumier, F. [Laboratoire de Metallurgie Physique - UMR 6630 CNRS, Department of Materials Sciences, University of Poitiers (France); Guittet, M.J. [Service de Physique et de Chimie des Surfaces et des Interfaces, DSM/DRECAM/SPCSI, CEA Saclay, 91191 Gif sur Yvette Cedex (France); Gautier-Soyer, M. [Service de Physique et de Chimie des Surfaces et des Interfaces, DSM/DRECAM/SPCSI, CEA Saclay, 91191 Gif sur Yvette Cedex (France)], E-mail:; Satet, R.; Hoffmann, M.J. [Institut fuer Keramik im Maschinenbau, Universitaet Karlsruhe (Thailand), Haid-und-Neu-Strasse 7, D 76131 Karlsruhe (Germany); Becher, P.F.; Painter, G.S. [Metals and Ceramics Division, Oak Ridge National Laboratory, Oak Ridge, TN (United States)


    Two series of oxynitride glasses, RE-Si-Mg-O-N (M=Mg, Al ; RE=La, Lu), have been studied by X-Ray photoelectron spectroscopy (XPS). The oxygen 1s photoelectron lineshape reveals a striking difference depending on the rare earth, both in the Mg series and in the Al series. Specifically, the oxygen 1s photoelectron lines of the La doped glasses are broader than the ones of the Lu doped glasses. This result is an experimental evidence that Lu has a larger affinity for oxygen versus nitrogen than La, as theoretically predicted by the first-principles calculations by Painter et al.

  5. Composition and local bonding in RE-Si-M-O-N (M = Mg, Al ; RE = La, Lu) glasses

    Energy Technology Data Exchange (ETDEWEB)

    Fouquet, V [French Atomic Energy Commission (CEA), Centre de Saclay, Gif sur Yvette; Paumier, F [University of Poitiers, France; Guittet, M [French Atomic Energy Commission (CEA), Centre de Saclay, Gif sur Yvette; Gautier-Soyer, M [French Atomic Energy Commission (CEA), Centre de Saclay, Gif sur Yvette; Satet, R. L. [Universituet Karlsruhe, Germany; Hoffmann, M. J. [Universituet Karlsruhe, Germany; Becher, Paul F [ORNL; Painter, Gayle S [ORNL


    Two series of oxynitride glasses, RE-Si-Mg-O-N (M = Mg, Al ; RE = La, Lu), have been studied by X-Ray photoelectron spectroscopy (XPS). The oxygen 1s photoelectron lineshape reveals a striking di erence depending on the rare earth, both in the Mg series and in the Al series. Actually, the oxygen 1s photoelectron lines of the La doped glasses are broader than the ones of the Lu doped glasses. This result is an experimental evidence that Lu has a larger a nity for oxygen versus nitrogen than La, as theoretically predicted by the ab initio calculations by Painter et al.

  6. 71 FR 5717 - Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU... (United States)


    ...The FHWA, to ensure widespread distribution of implementation guidance on the Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU) (Pub. L. 109-59, 119 Stat. 1144), is announcing the availability of a Web site that contains SAFETEA-LU implementation guidance issued by the FHWA. The implementation guidance is available at the following URL: http:// This Web site will serve as a consolidated location to obtain all SAFETEA-LU implementation guidance issued by the agency.


    Directory of Open Access Journals (Sweden)

    Ahmet SAÇKESEN (M.A.H.


    Full Text Available Importance and function of Turkish woman will be analyzed during historical process in this article named as “Types of Woman in Er Tabıldı Epic” Types of woman in Er Tabıldı Legend will be explained as ideal wife and mother types ideal lover and assistant types.

  8. Det er ikke længere samfundet skyld

    DEFF Research Database (Denmark)

    Nielsen, Jens Christian; Sørensen, Niels Ulrik


    'Det er mig, den er gal med. Jeg må tage mig sammen'. Sådan reagerer unge, når de møder modgang. Offermentaliteten er væk. Troen på det individuelle ansvar råder. For de skrøbeligste er resultatet destruktiv selvbebrejdelse. Det viser forskningsprojetet Når det er svært at være i ung i DK....

  9. Determination of rare earths and thorium in apatites by thermal and epithermal neutron-activation analysis. (United States)

    Brunfelt, A O; Roelandts, I


    A procedure is described for the non-destructive determination of Na, Mn, La, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Yb, Lu and Th in apatites by thermal and epithermal neutron-activation of independent portions of the material. The method was applied to three apatites with different contents. The precision obtained was better than +/-5% for La, Ce, Sm, Eu, Gd, Tb and Dy and +/-20% for Yb, Nd, Ho, Er and Lu for an apatite with a total rare-earth oxide content of the order of 1%. Determination of Ce, Tb and Yb could only be carried out with thermal neutron-activation analysis, while Gd, Ho and Er could only be determined after irradiation with epithermal neutrons.

  10. Hydrocodone Bitartrate ER (Hysingla® ER): A Review in Chronic Pain. (United States)

    Dhillon, Sohita


    Hydrocodone bitartrate extended-release (Hysingla® ER; referred to hereafter as hydrocodone ER) was the first single-entity hydrocodone formulation recognized by the US FDA as having abuse-deterrent properties. It is indicated for the management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Once-daily oral hydrocodone ER provides consistent plasma hydrocodone concentrations and sustained analgesia over the 24-h dosing interval. Its physicochemical properties render hydrocodone ER harder to manipulate physically, which is expected to deter intranasal, intravenous and oral abuse. For instance, oral hydrocodone ER (intact or chewed) significantly reduced drug liking relative to hydrocodone solution in a clinical study. In two large phase III studies in patients with chronic pain, hydrocodone ER reduced pain intensity, with its effects seen early (during dose titration) and maintained during ≤76 weeks' treatment. During maintenance therapy, the majority of patients continued hydrocodone ER at the dosage achieved at the end of dose titration and without requiring increased doses of supplemental pain medication, suggesting adequate pain management. Hydrocodone ER was generally well tolerated, with a safety profile consistent with that seen with other μ-opioid analgesics. However, like other opioids, it is associated with risks of addiction, abuse/misuse and serious adverse events (AEs), including respiratory depression, withdrawal, physical dependence and overdose. Although large postmarketing studies are needed to determine whether the abuse-deterrent properties of hydrocodone ER result in meaningful reductions in abuse, misuse and related adverse clinical outcomes, current evidence indicates that hydrocodone ER is a useful treatment option for patients with chronic pain.

  11. Synthesis, characterization, and in vitro evaluation of a radio-metal organic framework composed of in vivo generator {sup 166}Dy/{sup 166}Ho and DOTMP as a novel agent for bone marrow ablation

    Energy Technology Data Exchange (ETDEWEB)

    Vosoghi, Sara; Shirvani-Arani, Simindokht; Bahrami-Samani, Ali; Salek, Nafise; Mirerezaei, Ehsan; Jalilian, Amir Reza [Nuclear Science and Technology Research Institute (NSTRI), Tehran (Iran, Islamic Republic of)


    In this study, the MOF concept contributed to the preparation of a novel, bone-ablating agent composed of Cu(II) using the in vivo generator {sup 166}Dy/{sup 166}Ho and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethylene phosphonic acid (DOTMP). The product was characterized (IR, elemental analysis: CHN, ICM-MS, PIXE, DLS, XRD) and quality-controlled (radio-thin layer chromatography (RTLC)). The stability and in vitro hydroxyapatite binding was checked up to one week at 37 C in human serum. Radio-MOF crystals and colloidal radio-MOF particles were obtained by varying the synthesizing conditions (including pH and temperature), and they had similar IR patterns and similar elemental analysis results. The estimated chemical formula was [1Lu-1Cu-1Cl-1DOTMP] for both. The final product was synthesized at pH = 8 while stirring at room temperature using {sup 166}Dy/{sup 166}Ho-nitrate, CuCl{sub 2}, and DOTMP (yield > 99%, RTLC). Dynamic light scattering (DLS) measurements showed particles in the size range of 60 to 100 nm for the resultant radio-MOF particles (RMP). In vitro binding experiments showed acceptable bone-seeking affinity of the prepared formula even after one week of storage in human serum at 37 C. Importantly, this is the first study of the use of the MOF concept to provide a highly-stable organometallic compound containing {sup 166}Dy/{sup 166}Ho in vivo generator for bone marrow ablation.

  12. Occupational Competence for Improving Industrial Enterprise Competitive Standards / Profesní Kompetence Pro Zlepšení Konkurenčních Standardů Průmyslového Podniku

    Directory of Open Access Journals (Sweden)

    Krčmarská Lucie


    Full Text Available Úspěchy firem jsou většinou poměřovány jejich dosaženými výsledky. Za základ těchto úspěchů lze považovat úroveň kompetencí lidí, kteří pro firmu pracují. Kompetence lidí chápeme jako souhrn dosahovaného výkonu a přinášeného potenciálu. Jestliže chybí jedno, pak chybí i kompetence jako celek. Problémy, které vznikají ve firmách můžete tedy převést na chybějící nebo nedostačující kompetence a je tedy nutné doplnit to, co v oblasti kompetencí chybí. Uvědomí-li si firma význam kompetencí lidí ve vztahu k úspěchům nebo neúspěchům a zaměří-li se na jejich rozvoj, odstraňuje tím příčiny vznikajících problémů, ne jen jejich viditelné problémy. Článek je zaměřen na posouzení kompetencí a kompetenčních modelů jako významného nástroje v oblasti řízení lidských zdrojů.

  13. Behaviour of REEs in a tropical estuary and adjacent continental ...

    Indian Academy of Sciences (India)

    The rare earth elements like La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu and the heavy metals like Mg, V, Cr, Mn, Fe, Cu, Zn, U, Th were analysed by using standard analytical methods. The Post-Archean Australian Shale composition was used to normalise the rare earth elements. It was found that the sediments ...

  14. Lightweight high performance ceramic material (United States)

    Nunn, Stephen D [Knoxville, TN


    A sintered ceramic composition includes at least 50 wt. % boron carbide and at least 0.01 wt. % of at least one element selected from the group consisting of Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy Ho, Er, Tm, Yb, and Lu, the sintered ceramic composition being characterized by a density of at least 90% of theoretical density.

  15. Sport er hverken sundt eller social

    DEFF Research Database (Denmark)

    Andersen, Tem Frank


    Jeg deler ikke Lasch og Kayser Nielsens konklusioner, selvom jeg er meget enig i, at sport er dirty business. Min analyse peger i den retning, at sporten i sin organiserede form ikke er eller kan fungere som leverandør af nogen ”pakkeløsning”. Men sport kan sagtens bidrage med brudstykker til noget...... meningsfuldt, for det enkelte menneske, eller det enkelte lokalsamfund. Sporten kan ikke længere, hvis den skal fremstå som noget ideal, levere en hel pakke, en fuldstændig myte med tilhørende ritualer. Sport kan imidlertid som projekt fortsat godt levere stof til den meningsskabende fortælling om identitet...


    Energy Technology Data Exchange (ETDEWEB)

    Gerald Heymsfield


    Data was taken with the NASA ER-2 aircraft with the Cloud Radar System and other instruments in conjunction with the DOE ARM CLASIC field campaign. The flights were near the SGP site in north Central Oklahoma and targeted small developing convection. The CRS is a 94 GHz nadir pointing Doppler radar. Also on board the ER-2 was the Cloud Physics Lidar (CPL). Seven science flights were conducted but the weather conditions did not cooperate in that there was neither developing convection, or there was heavy rain.

  17. Ho:YLF Laser Pumped by TM:Fiber Laser

    Directory of Open Access Journals (Sweden)

    Mizutani Kohei


    Full Text Available A 2-micron Ho:YLF laser end-pumped by 1.94-micron Tm:fiber laser is described. A ring resonator of 3m length is adopted for the oscillator. The laser is a master oscillator and an amplifier system. It is operated at high repetition rate of 200-5000 Hz in room temperature. The laser outputs were about 9W in CW and more than 6W in Q-switched operation. This laser was developed to be used for wind and CO2 measurements.

  18. Lifshitz holographic superconductor in Hořava–Lifshitz gravity

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Cheng-Jian, E-mail: [Department of Physics, Nanchang University, Nanchang, 330031 (China); Center for Relativistic Astrophysics and High Energy Physics, Nanchang University, Nanchang 330031 (China); Kuang, Xiao-Mei, E-mail: [Instituto de Física, Pontificia Universidad Católica de Valparaíso, Casilla 4059, Valparaíso (Chile); Shu, Fu-Wen, E-mail: [Department of Physics, Nanchang University, Nanchang, 330031 (China); Center for Relativistic Astrophysics and High Energy Physics, Nanchang University, Nanchang 330031 (China)


    We study the holographic phase transition of superconductor dual to a Lifshitz black brane probed by an anisotropic scalar field in the probe limit in Hořava–Lifshitz gravity. With the use of numerical and analytical method, we investigate how the critical temperature of the condensation is affected by the Lifshitz exponent z, α-correction term in the action as well as the dimensions of the gravity. We also numerically explore the condensation of the dual operator and optical conductivity of the holographic system. Various interesting properties of the holographic condensation affected by the parameters of model are discussed.

  19. Synthesis and luminescent properties of uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres. (United States)

    Gao, Yu; Yu, He; Shi, Cheng; Zhao, Guiyan; Bi, Yanfeng; Xu, Baotong; Ding, Fu; Sun, Yaguang; Xu, Zhenhe


    Uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres with diameters of about 2.4 µm have been successfully synthesized by the combination of a facile homogeneous precipitation approach, an ion-exchange process and a calcination process. The possible formation mechanism for the hollow microspheres was presented. Furthermore, the luminescence properties revealed that the LuPO4:Eu3+ and LuPO4:Tb3+ phosphors show strong orange-red and green emissions under ultraviolet excitation, respectively, which endows this material with potential application in many fields, such as light display systems and optoelectronic devices. Since the synthetic process can be carried out at mild conditions, it should be straightforward to scale up the entire process for large-scale production of the LuPO4 hollow microspheres. Furthermore, this general and simple method may be of much significance in the synthesis of many other inorganic materials.

  20. Synthesis and luminescent properties of uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres (United States)

    Gao, Yu; Yu, He; Shi, Cheng; Zhao, Guiyan; Bi, Yanfeng; Ding, Fu; Sun, Yaguang; Xu, Zhenhe


    Uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres with diameters of about 2.4 µm have been successfully synthesized by the combination of a facile homogeneous precipitation approach, an ion-exchange process and a calcination process. The possible formation mechanism for the hollow microspheres was presented. Furthermore, the luminescence properties revealed that the LuPO4:Eu3+ and LuPO4:Tb3+ phosphors show strong orange-red and green emissions under ultraviolet excitation, respectively, which endows this material with potential application in many fields, such as light display systems and optoelectronic devices. Since the synthetic process can be carried out at mild conditions, it should be straightforward to scale up the entire process for large-scale production of the LuPO4 hollow microspheres. Furthermore, this general and simple method may be of much significance in the synthesis of many other inorganic materials. PMID:29308268

  1. Excitation functions for proton-induced reactions on natural hafnium: Production of 177Lu for medical use (United States)

    Siiskonen, T.; Huikari, J.; Haavisto, T.; Bergman, J.; Heselius, S.-J.; Lill, J.-O.; Lönnroth, T.; Peräjärvi, K.; Vartti, V.-P.


    There is an increasing interest in using radioisotopes of rare earth elements for internal radiotherapy and for imaging in nuclear medicine. 177Lu is one of the promising radionuclides. This article reports on the first measurements of the excitation function for the production of 177Lu with proton-beam energies up to 17 MeV on natural hafnium targets. The experimental cross sections for the reaction natHf(p,x) 177Lu were obtained by the activation of a stacked-foil target and subsequent gamma spectrometry. Theoretical cross sections were calculated up to 35 MeV with the EMPIRE nuclear reaction model code. The measured and calculated cross sections were used for deriving the thick-target yields and for estimating the production of other nuclides than 177Lu. Measured production cross sections of 175,176,177,178Ta on the same target are also presented.

  2. Synthesis and luminescent properties of uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres (United States)

    Gao, Yu; Yu, He; Shi, Cheng; Zhao, Guiyan; Bi, Yanfeng; Xu, Baotong; Ding, Fu; Sun, Yaguang; Xu, Zhenhe


    Uniform monodisperse LuPO4:Eu3+/Tb3+ hollow microspheres with diameters of about 2.4 µm have been successfully synthesized by the combination of a facile homogeneous precipitation approach, an ion-exchange process and a calcination process. The possible formation mechanism for the hollow microspheres was presented. Furthermore, the luminescence properties revealed that the LuPO4:Eu3+ and LuPO4:Tb3+ phosphors show strong orange-red and green emissions under ultraviolet excitation, respectively, which endows this material with potential application in many fields, such as light display systems and optoelectronic devices. Since the synthetic process can be carried out at mild conditions, it should be straightforward to scale up the entire process for large-scale production of the LuPO4 hollow microspheres. Furthermore, this general and simple method may be of much significance in the synthesis of many other inorganic materials.

  3. Analysis of heat capacity and Mössbauer data for LuZnSn2 compound

    Directory of Open Access Journals (Sweden)

    Łątka Kazimierz


    Full Text Available New analysis of heat capacity data is presented for LuZnSn2 compound that takes into account anharmonic effects together with the existence of Einstein modes. 119mSn Mössbauer spectroscopy was used to monitor the hyperfine parameters at the two crystallographically inequivalent Sn sites in the studied compound. The problem of non-unique mathematical resonance spectrum description and the problem how to choose physically meaningful set of hyperfine parameters will be thoroughly discussed. Measured quadrupole interaction constants by 119mSn Mössbauer spectroscopy give estimations for Vzz component of electric field gradient tensor at both Sn sites in LuZnSn2.

  4. Electronic Raman scattering and the renormalization of the electron spectrum in LuB{sub 12}

    Energy Technology Data Exchange (ETDEWEB)

    Ponosov, Yu. S., E-mail:; Streltsov, S. V., E-mail: [Russian Academy of Sciences, Institute of Metal Physics, Ural Branch (Russian Federation); Levchenko, A. V.; Filippov, V. B. [National Academy of Sciences of Ukraine, Frantsevich Institute of Materials Science Problems (Ukraine)


    The electronic Raman scattering in LuB{sub 12} single crystals of various isotope compositions is studied in the temperature range 10–650 K. The shape and the energy position of spectral maxima depend on the direction and magnitude of a probe wavevector, the temperature, and the excitation symmetry and remain unchanged when the isotope composition changes. Experimental spectra are compared with the spectra simulated on the basis of a calculated electronic structure. The experimental results are successfully described when the electron spectrum renormalization effects caused by electron–phonon coupling are taken into account. This confirms that the origin of the observed spectra in LuB{sub 12} is due to Raman scattering by electrons. A comparison of the calculated and experimental data makes it possible to determine the coupling constant (λ{sub ep} = 0.32) that gives the correct superconducting transition temperature.

  5. Preparation and spectroscopic characterization of Lu 2O 3:Eu 3+ nanopowders and ceramics (United States)

    Wang, Zhifang; Zhang, Weiping; Lin, Lin; You, Baogui; Fu, Yibing; Yin, Min


    Nanocrystalline Lu2O3 doping with different Eu3+ concentrations was prepared by co-precipitation method. The crystal structure and morphology were analyzed by means of XRD and HRTEM. The resultant powders were sintered into translucent ceramics in vacuum and then in nitrogen without any additive. The surface morphology of the unpolished sintered specimens was characterized using SEM. The excitation and emission spectra of Lu2O3:Eu3+ powders and ceramics were measured at room temperature by using synchrotron radiation as the light source. Pronounced changes of the spectroscopic properties with increasing Eu3+ content were observed and the reasons were studied. The fluorescent lifetimes of nanopowders shortened obviously with increasing Eu content, but no such effect was observed for the sintered ceramics. Luminescence of ceramics samples decays faster than the corresponding nanopowders.

  6. The absorption property of single crystal LuBiIG garnet film in terahertz band (United States)

    Yang, Qing-Hui; Zhang, Huai-Wu; Wen, Qi-Ye; Liu, Ying-Li


    In this paper, a hypothesis has been brought forward that the materials with low propagation loss in both optical and microwave band may exhibit good performance in terahertz (THz) band because THz wave band interspaces those two wave bands. Several kinds of single crystal garnet films were investigated and we found that the Lu2.1Bi0.9Fe5O12 film which grows by liquid phase epitaxy (LPE) from PbO-free flux has the best absorption properties in both microwave and optical band. In THz range, our hypothesis is well confirmed by a THz-TDS measurement which shows that the absorption coefficient of LuBiIG film is 0.05-0.3 cm-1, and the minimum value appears at 2.24 THz.

  7. An implict LU scheme for the Euler equations applied to arbitrary cascades. [new method of factoring (United States)

    Buratynski, E. K.; Caughey, D. A.


    An implicit scheme for solving the Euler equations is derived and demonstrated. The alternating-direction implicit (ADI) technique is modified, using two implicit-operator factors corresponding to lower-block-diagonal (L) or upper-block-diagonal (U) algebraic systems which can be easily inverted. The resulting LU scheme is implemented in finite-volume mode and applied to 2D subsonic and transonic cascade flows with differing degrees of geometric complexity. The results are presented graphically and found to be in good agreement with those of other numerical and analytical approaches. The LU method is also 2.0-3.4 times faster than ADI, suggesting its value in calculating 3D problems.

  8. SuperLU{_}DIST: A scalable distributed-memory sparse direct solver for unsymmetric linear systems

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xiaoye S.; Demmel, James W.


    In this paper, we present the main algorithmic features in the software package SuperLU{_}DIST, a distributed-memory sparse direct solver for large sets of linear equations. We give in detail our parallelization strategies, with focus on scalability issues, and demonstrate the parallel performance and scalability on current machines. The solver is based on sparse Gaussian elimination, with an innovative static pivoting strategy proposed earlier by the authors. The main advantage of static pivoting over classical partial pivoting is that it permits a priori determination of data structures and communication pattern for sparse Gaussian elimination, which makes it more scalable on distributed memory machines. Based on this a priori knowledge, we designed highly parallel and scalable algorithms for both LU decomposition and triangular solve and we show that they are suitable for large-scale distributed memory machines.

  9. Single-clad Tm-Ho:fiber amplifier for high-power sub-100-fs pulses around 1.9 μm. (United States)

    Coluccelli, Nicola; Cassinerio, Marco; Laporta, Paolo; Galzerano, Gianluca


    A Tm-Ho:fiber amplifier based on single-clad geometry is demonstrated for the generation of high-power femtosecond pulses around 1.9 μm. The amplifier is seeded by the low-power Raman soliton generated by an Er:fiber femtosecond laser. Pulse trains at a repetition rate of 250 MHz tunable from 1.84 to 1.92 μm with corresponding powers from 2.6 to 3 W and durations from 80 to 105 fs have been obtained. Beating with a single-frequency Tm laser has shown that the pulse coherence is highly preserved. The overall power fluctuations have been measured to be as low as 0.6%.

  10. Crystal structure and Mössbauer studies of the isotypic Fe6-cluster compounds RE15[Fe8C25], RE=Dy, Ho

    KAUST Repository

    Davaasuren, Bambar


    The carboferrates RE15[Fe8C25] (RE=Dy, Ho) were prepared from mixtures of the elements by arc-melting followed with subsequent annealing at 1373 K. The crystal structures were determined from single crystal X-ray diffraction data and revealed an isotypic relationship to Er15[Fe8C25] (hP48, P321). The main feature of the crystal structure is given by Fe6 cluster units characterized by covalent Fe-Fe bonding interactions. 57Fe Mössbauer spectra of Dy15[Fe8C25] were fitted by three subspectra with relative spectral weights of about 3:3:2 which is in general agreement with the crystal structure. Below 50 K, an onset of magnetic hyperfine fields at the three iron sites is observed which is supposed to be caused by dipolar fields arising from neighboring, slowly relaxing Dy magnetic moments.

  11. Caries inhibition potential of Er:YAG and Er:YSGG laser radiation (United States)

    Fried, Daniel; Featherstone, John D. B.; Visuri, Steven R.; Seka, Wolf D.; Walsh, Joseph T., Jr.


    Dental hard tissues can be ablated efficiency by (lambda) equals 3 micrometers laser irradiation with minimal subsurface thermal damage. However, the potential of lasers operating in the region of the infrared for caries preventive treatments has not been investigated. In this study, the caries inhibition potential of Er:YAG ((lambda) equals 2.94 micrometers ) and Er:YSGG ((lambda) equals 2.79 micrometers ) laser radiation on dental enamel was evaluated at various irradiation intensities. Pulsed IR radiometry and scanning electron microscopy (SEM) were used to measure the time-resolved surface temperatures during laser irradiation and to detect changes in the surface morphology. The magnitude and temporal evolution of the surface temperature during multiple pulse irradiation of the tissue was dependent on the wavelength, irradiation intensity, and the number of laser pulses. Radiometry and SEM micrographs indicated that ablation was initiated at temperatures of approximately 300 degree(s)C for Er:YAG and 800 degree(s)C for Er:YSGG laser irradiation, well below the melting and vaporization temperatures of the carbonated hydroxyapatite mineral component (m.p. equals 1200 degree(s)C). Nevertheless, there was marked caries inhibition for irradiation intensities below those temperature thresholds, notably 60% and 40% inhibition was achieved after Er:YSGG and Er:YAG laser irradiation, respectively. These results indicate that the Er:YSGG laser can be used effectively for both preventive dental treatments and for hard tissue removal.

  12. Somatostatin-based Radiopeptide Therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in Neuroendocrine Tumors


    Romer A Seiler D Marincek N Brunner P Koller MT Ng QK Maecke HR Muller-Brand J Rochlitz C B; riel M and Walter MA


    PURPOSE: Somatostatin based radiopeptide treatment is generally performed using the ß emitting radionuclides (90)Y or (177)Lu. The present study aimed at comparing benefits and harms of both therapeutic approaches. METHODS: In a comparative cohort study patients with advanced neuroendocrine tumours underwent repeated cycles of [(90)Y DOTA] TOC or [(177)Lu DOTA] TOC until progression of disease or permanent adverse events. Multivariable Cox regression and competing risks regression were emplo...

  13. Muslim Selbstverständnis: Ahmet Davutoğlu Answers Husserl’s Crisis of European Sciences




    In formulating his understanding of Islamic history, thought and politics, the Turkish Muslim thinker Ahmet Davutoğlu adopts the German philosopher Edmund Husserl’s formulation of phenomenology – or, philosophy of consciousness. Both Husserl and Davutoğlu perceive a crisis in humanity and identify its causes in scientism and logical positivism, against which they develop their respective phenomenological alternatives. This article places in parallel Husserl’s stylised history of Western thoug...

  14. Somatostatin-based radiopeptide therapy with [177Lu-DOTA]-TOC versus [90Y-DOTA]-TOC in neuroendocrine tumours. (United States)

    Romer, A; Seiler, D; Marincek, N; Brunner, P; Koller, M T; Ng, Q K T; Maecke, H R; Müller-Brand, J; Rochlitz, C; Briel, M; Schindler, C; Walter, M A


    Somatostatin-based radiopeptide treatment is generally performed using the β-emitting radionuclides (90)Y or (177)Lu. The present study aimed at comparing benefits and harms of both therapeutic approaches. In a comparative cohort study, patients with advanced neuroendocrine tumours underwent repeated cycles of [(90)Y-DOTA]-TOC or [(177)Lu-DOTA]-TOC until progression of disease or permanent adverse events. Multivariable Cox regression and competing risks regression were employed to examine predictors of survival and adverse events for both treatment groups. Overall, 910 patients underwent 1,804 cycles of [(90)Y-DOTA]-TOC and 141 patients underwent 259 cycles of [(177)Lu-DOTA]-TOC. The median survival after [(177)Lu-DOTA]-TOC and after [(90)Y-DOTA]-TOC was comparable (45.5 months versus 35.9 months, hazard ratio 0.91, 95% confidence interval 0.63-1.30, p = 0.49). Subgroup analyses revealed a significantly longer survival for [(177)Lu-DOTA]-TOC over [(90)Y-DOTA]-TOC in patients with low tumour uptake, solitary lesions and extra-hepatic lesions. The rate of severe transient haematotoxicities was lower after [(177)Lu-DOTA]-TOC treatment (1.4 vs 10.1%, p = 0.001), while the rate of severe permanent renal toxicities was similar in both treatment groups (9.2 vs 7.8%, p = 0.32). The present results revealed no difference in median overall survival after [(177)Lu-DOTA]-TOC and [(90)Y-DOTA]-TOC. Furthermore, [(177)Lu-DOTA]-TOC was less haematotoxic than [(90)Y-DOTA]-TOC.

  15. Production, biodistribution assessment and dosimetric evaluation of 177Lu-TTHMP as a bone pain palliation agent


    samaneh zolghadri; hassan yousefnia; amir reza jalilian; mohammad ghannadi-maragheh


    Objective(s): Recently, bone-avid radiopharmaceuticals have been shown to have potential benefits for the treatment of widespread bone metastases. Although 177Lutriethylene tetramine hexa methylene phosphonic acid (abbreviated as 177Lu- TTHMP), as an agent for bone pain palliation, has been evaluated in previous studies, there are large discrepancies between the obtained results. In this study, production, quality control, biodistribution, and dose evaluation of 177Lu-TTHM...


    Directory of Open Access Journals (Sweden)

    Mehmet Emin BARS (M.A.H.


    Full Text Available The epic of Köroğlu is one of the most loved epics whichreaches today from long centuries and stil keeps its place ofimportance in narration tradition. Đt is an epical work that leftdeep influences over Turkish world and over nations livedtogether with Turks for long centuries. Đt is a monument,binding the past and the present. Even today when taken intoconsideration of the wideness of its narreted and listenedgeographical area its importance from the view of maintainingthe cultural integrity between Turks will be understood muchbeter. Đt is difficult to come across such a work whichmaintains its vitality and dynamism with a wide performancearea in the lives of other nations. The perfection and thereachment of education level in Turkish epic tradition are thefactors which cause this result. Đn our writing the concepts ofhorse, woman and weapon which take place in Turkomanvariant of Köroğlu will be discussed.


    Directory of Open Access Journals (Sweden)

    Mehmet Emin BARS (M.A.H.


    Full Text Available The epic of Köroğlu is an epical work that left deep influencesall over the Turkish world and over the nations lived together withTurks for long centuries. Even today when taken into consideration ofthe wideness of its narrated and listened geopraphical area, itsimportance from the view of maintaining the cultural integritybetween Turks will be understood much better. Đt is difficult to comeacross such a work like the epic of Köroğlu which maintains itsimportance with a wide performance area, in the lives of other nations.As for proverbs they are the expressions which tell a nation’s standardof judgement. These expressions containing the acquirement of thelife experiences for centuries inform that nation’s thought, yearning,criticism, observation and ideas. They advise people the principles andthe rules aiming to teach the good, the beautiful and the truth. Đn ourwriting the proverbs which take place in Turkoman variant of Köroğluwill be discussed.

  18. Measurement of conversion coefficients in normal and triaxial strongly deformed bands in {sup 167}Lu.

    Energy Technology Data Exchange (ETDEWEB)

    Gurdal, G.; Beausang, C. W.; Brenner, D. S.; Ai, H.; Casten, R. F.; Crider, B.; Heinz, A.; Williams, E.; Hartley, D. J.; Carpenter, M. P.; Hecht, A. A.; Janssens, R. V. F.; Lauritsen, T.; Lister, C. J.; Raabe, R.; Seweryniak, D.; Zhu, S.; Saladin, J. X.; Physics; Yale Univ.; Clark Univ.; Univ. of Richmond; United States Naval Academy; Univ. of Maryland; Univ. of Pittsburgh


    Internal conversion coefficients have been measured for transitions in both normal deformed and triaxial strongly deformed bands in {sup 167}Lu using the Gammasphere and ICE Ball spectrometers. The results for all in-band transitions are consistent with E2 multipolarity. Upper limits are determined for the internal conversion coefficients for linking transitions between TSD Band 2 and TSD Band 1, the n{sub w} = 1 and n{sub w} = 0 wobbling bands, respectively.

  19. Neutron capture measurement on {sup 173}Lu at LANSCE with DANCE detector

    Energy Technology Data Exchange (ETDEWEB)

    Theroine, C.; Ebran, A.; Meot, V.; Roig, O. [CEA DAM DIF, F-91297 Arpajon (France); Bond, E. M.; Bredeweg, T. A.; Couture, A.; Haight, R. C.; Jandel, M.; Nortier, F. M.; O' Donnell, J. M.; Rundberg, R. S.; Taylor, W. A.; Ullmann, J. L.; Viera, D. J.; Wilhelmy, J. B.; Wouters, J. M. [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)


    The (n,{gamma}) cross section on the unstable {sup 173}Lu(t{sub 1/2} = 1.37y) has been measured from thermal energy up to 200 eV at Los Alamos Neutron Science Center (LANSCE) with The Detector for Advanced Neutron Capture Experiements (DANCE). The main aim of this study is to validate and optimize reaction models for unstable nucleus. A preliminary capture yield will be presented in this paper.

  20. First principle calculation of structure and lattice dynamics of Lu2Si2O7

    Directory of Open Access Journals (Sweden)

    Nazipov D.V.


    Full Text Available Ab initio calculations of crystal structure and Raman spectra has been performed for single crystal of lutetium pyrosilicate Lu2Si2O7. The types of fundamental vibrations, their frequencies and intensities in the Raman spectrum has been obtained for two polarizations. Calculations were made in the framework of density functional theory (DFT with hybrid functionals. The isotopic substitution was calculated for all inequivalent ions in cell. The results in a good agreement with experimental data.