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  1. Epoetin Delta Reduces Oxidative Stress in Primary Human Renal Tubular Cells

    Directory of Open Access Journals (Sweden)

    Annelies De Beuf

    2010-01-01

    Full Text Available Erythropoietin (EPO exerts (renal tissue protective effects. Since it is unclear whether this is a direct effect of EPO on the kidney or not, we investigated whether EPO is able to protect human renal tubular epithelial cells (hTECs from oxidative stress and if so which pathways are involved. EPO (epoetin delta could protect hTECs against oxidative stress by a dose-dependent inhibition of reactive oxygen species formation. This protective effect is possibly related to the membranous expression of the EPO receptor (EPOR since our data point to the membranous EPOR expression as a prerequisite for this protective effect. Oxidative stress reduction went along with the upregulation of renoprotective genes. Whilst three of these, heme oxygenase-1 (HO-1, aquaporin-1 (AQP-1, and B-cell CLL/lymphoma 2 (Bcl-2 have already been associated with EPO-induced renoprotection, this study for the first time suggests carboxypeptidase M (CPM, dipeptidyl peptidase IV (DPPIV, and cytoglobin (Cygb to play a role in this process.

  2. Quality of Original and Biosimilar Epoetin Products

    NARCIS (Netherlands)

    Brinks, V.|info:eu-repo/dai/nl/31395979X; Hawe, A.; Basmeleh, A.H.H.|info:eu-repo/dai/nl/337907331; Joachin-Rodriguez, L.; Haselberg, R.|info:eu-repo/dai/nl/304822647; Somsen, G.W.|info:eu-repo/dai/nl/117149357; Jiskoot, W.|info:eu-repo/dai/nl/084557397; Schellekens, H.|info:eu-repo/dai/nl/068406762

    2011-01-01

    Purpose: To compare the quality of therapeutic erythropoietin (EPO) products, including two biosimilars, with respect to content, aggregation, isoform profile and potency. Methods: Two original products, Eprex (epoetin alfa) and Dynepo (epoetin delta), and two biosimilar products, Binocrit (epoetin

  3. Quality of original and biosimilar epoetin products.

    Science.gov (United States)

    Brinks, Vera; Hawe, Andrea; Basmeleh, Abdul H H; Joachin-Rodriguez, Liliana; Haselberg, Rob; Somsen, Govert W; Jiskoot, Wim; Schellekens, Huub

    2011-02-01

    To compare the quality of therapeutic erythropoietin (EPO) products, including two biosimilars, with respect to content, aggregation, isoform profile and potency. Two original products, Eprex (epoetin alpha) and Dynepo (epoetin delta), and two biosimilar products, Binocrit (epoetin alpha) and Retacrit (epoetin zeta), were compared using (1) high performance size exclusion chromatography, (2) ELISA, (3) SDS-PAGE, (4) capillary zone electrophoresis and (5) in-vivo potency. Tested EPO products differed in content, isoform composition, and potency. Of the tested products, the biosimilars have the same or even better quality as the originals. Especially, the potency of originals may significantly differ from the value on the label.

  4. Low-dosage epoetin in maintenance haemodialysis: costs and quality-of-life improvement.

    Science.gov (United States)

    Harris, D C

    1994-01-01

    Decisions about epoetin (recombinant human erythropoetin) dosage and target haematocrit in dialysis patients have been determined largely by the high acquisition cost of epoetin, but are made with incomplete knowledge about which target haematocrit gives the optimum clinical benefit. Haematopoietic response to epoetin may be determined by pharmacodynamic factors such as rate and frequency of administration, as well as by individual patient characteristics such as ethnicity. Resistance to epoetin may be due to iron or vitamin deficiency, natural or exogenous inhibitors of erythropoiesis and bone marrow fibrosis. The high acquisition cost of epoetin must be considered along with a number of other factors that can influence the true cost of epoetin treatment. Hidden costs of epoetin treatment include administration costs, changes in other treatments, extra laboratory tests and adverse events. Administration costs and extra laboratory surveillance add little to overall cost. Depletion of iron stores, hypertension, increased blood coagulability and reduced dialyser efficiency resulting from epoetin treatment may all add a small additional component to the true cost. Severe complications with significant cost implications are rare. Amongst the various components of true cost, only the acquisition cost can definitely be reduced by low dosage treatment. Balanced against the true and potential costs of epoetin are a number of benefits which can result in potential savings. The need for blood transfusion is all but abolished, avoiding the cost of transfusion and its complications. Sensitisation against histocompatibility antigens is reduced by avoiding transfusion, and so the waiting time for cadaveric transplantation may be reduced. Rates of hospitalisation for all causes, especially those associated with anaemia, may be reduced by epoetin treatment. By improving well-being, epoetin may allow patients to be transferred to minimal-care units or home where dialysis can be

  5. Managing anemia with epoetin alfa in patients with rectal cancer

    International Nuclear Information System (INIS)

    Velenik, V.; Oblak, I.; Kodre, V.

    2005-01-01

    Background. Anemia is one of the most challenging problems in clinical oncology due to its high prevalence among the patients with malignant diseases. The purposes of our study were: (1) to assess the potential of epoetin alfa therapy to prevent the decline in Hb concentrations that typically accompanies chemotherapy/ radiotherapy (ChT/RT) of the patients with rectal cancer; (2) to test the hypothesis that the use of epoetin alfa significantly reduces the transfusion requirements in the patients with rectal cancer treated with ChT/RT after surgery, and (3) to evaluate the safety profile of the administration of epoetin alfa in the clinical setting. Methods. Sixty patients who underwent surgery for rectal cancer were prospectively enrolled. Group A consisted of 39 patients with Hb concentrations ≤13 g/dl at the start of ChT/RT following surgery, and group B of 17 patients with Hb concentrations ≥13 g/dl at the start of ChT/RT following surgery, but whose Hb concentrations fell below 13 g/dl during the ChT/RT protocol. The starting dose of epoetin alfa in both groups was 10,000 IU subcutaneously (sc) three times a week (tiw). The following major parameters were evaluated: (1) change in Hb concentrations relative to the baseline as measured at 4-week intervals, (2) allogenic blood transfusion requirements in relation to Hb concentrations, and (3) incidence and severity of adverse events and their potential relationship to epoetin alfa administration. Results. The study protocol was completed in 56/60 patients. In group A, a statistically significant increase in Hb concentration (p<0.001) was observed after the first 4 weeks of epoetin alfa treatment compared to the baseline values, with the mean increase of Hb concentration of 1.97 g/dl ± 0.91 g/dl and Hb concentrations remained significantly increased through the whole study (p=0.0017). In group B, a continuous decrease in Hb concentrations was observed during the first weeks of therapy, reaching the level of

  6. The Use of Epoetin-α in Revision Knee Arthroplasty

    Directory of Open Access Journals (Sweden)

    Lawrence A. Delasotta

    2012-01-01

    Full Text Available Introduction. To evaluate the efficacy of epoetin-α prior to revision total knee arthroplasty, we hypothesized that epoetin-α will reduce blood transfusion. Methods. Eighty-one patients were compared in this retrospective review; twenty-eight patients received our dosing regimen. All patients were mildly anemic. Epoetin-α to control (1 : 2 patient matching occurred so that one of two attending surgeons, gender, BMI, complexity of surgery, ASA score, and age were similar between groups. The clinical triggers for blood transfusion during or after the procedure were determined based on peri- and postoperative hemoglobin levels, ASA score, and/or clinical symptoms consistent with anemia. Blood salvage was not used. Results. Blood transfusion and length of stay were lower in the study group. None of the patients who received epoetin-α underwent transfusion. Hemoglobin increased from 11.97 to 13.8, preoperatively. Hemoglobin at day of surgery and time of discharge were higher. Gender, BMI, ASA score, total and hidden blood losses, calculated blood loss, preop PLT, PT, PTT, and INR were similar between groups. One Epogen patient had an uncomplicated DVT (3.6%. Conclusions. Epoetin-α may have a role in the mildly anemic revision knee patient. It may also decrease patient length of stay allowing for earlier readiness to resume normal activities and/or meet short-term milestones. A randomized study to evaluate the direct and indirect costs of such a treatment methodology in the mildly anemic revision patient may be warranted.

  7. Epoetin and Darbepoetin Treatment for Adults with Cancer

    Science.gov (United States)

    ... used for people with anemia who are receiving chemotherapy, and it is important for the doctor to rule out other causes of anemia and discuss the risks and benefits of each treatment option. Before starting treatment with epoetin or darbepoetin, ...

  8. Epoetin beta for the treatment of chemotherapy-induced anemia: an update

    Directory of Open Access Journals (Sweden)

    Galli L

    2015-03-01

    Full Text Available Luca Galli,1 Clara Ricci,2 Colin Gerard Egan2 1Oncology Unit 2, University Hospital of Pisa, Pisa, Italy; 2Primula Multimedia SRL, Pisa, Italy Abstract: Epoetin beta belongs to the class of erythropoiesis-stimulating agents (ESAs that are currently available to treat anemic patients receiving chemotherapy. Chemotherapy-induced anemia affects a high percentage of cancer patients and, due to its negative effects on disease outcome and the patient’s quality of life, should be treated when first diagnosed. Initial trials with ESAs have shown efficacy in improving quality of life and reducing the need for blood transfusions in patients with chemotherapy-induced anemia. However, recent meta-analyses have provided conflicting data on the impact of ESAs on survival and tumor progression. Here we provide an overview of these recent data and review the role of epoetin beta in the treatment of chemotherapy-induced anemia over the past 20 years. Keywords: epoetin beta, erythropoietin, chemotherapy, cancer, anemia, treatment

  9. Delta ferrite in the weld metal of reduced activation ferritic martensitic steel

    Energy Technology Data Exchange (ETDEWEB)

    Sam, Shiju, E-mail: shiju@ipr.res.in [Institute for Plasma Research, Gandhinagar, Gujarat 382 428 (India); Das, C.R.; Ramasubbu, V.; Albert, S.K.; Bhaduri, A.K.; Jayakumar, T. [Indira Gandhi Centre for Atomic Research, Kalpakkam 603 102 (India); Rajendra Kumar, E. [Institute for Plasma Research, Gandhinagar, Gujarat 382 428 (India)

    2014-12-15

    Formation of delta(δ)-ferrite in the weld metal, during autogenous bead-on-plate welding of Reduced Activation Ferritic Martensitic (RAFM) steel using Gas Tungsten Arc Welding (GTAW) process, has been studied. Composition of the alloy is such that delta-ferrite is not expected in the alloy; but examination of the weld metal revealed presence of delta-ferrite in the weld metal. Volume fraction of delta-ferrite is found to be higher in the weld interface than in the rest of the fusion zone. Decrease in the volume fraction of delta-ferrite, with an increase in preheat temperature or with an increase in heat input, is observed. Results indicate that the cooling rate experienced during welding affects the volume fraction of delta-ferrite retained in the weld metal and variation in the delta-ferrite content with cooling rate is explained with variation in the time that the weld metal spends in various temperature regimes in which delta-ferrite is stable for the alloy during its cooling from the liquid metal to the ambient temperature. This manuscript will discuss the effect of welding parameters on formation of delta-ferrite and its retention in the weld metal of RAFM steel.

  10. Alpha-, gamma- and delta-tocopherols reduce inflammatory angiogenesis in human microvascular endothelial cells.

    Science.gov (United States)

    Wells, Shannon R; Jennings, Merilyn H; Rome, Courtney; Hadjivassiliou, Vicky; Papas, Konstantinos A; Alexander, Jonathon S

    2010-07-01

    Vitamin E, a micronutrient (comprising alpha-, beta-, gamma- and delta-tocopherols, alpha-, beta-, gamma- and delta-tocotrienols), has documented antioxidant and non-antioxidant effects, some of which inhibit inflammation and angiogenesis. We compared the abilities of alpha-, gamma- and delta-tocopherols to regulate human blood cytotoxicity (BEC) and lymphatic endothelial cytotoxicity (LEC), proliferation, invasiveness, permeability, capillary formation and suppression of TNF-alpha-induced VCAM-1 as in vitro models of inflammatory angiogenesis. alpha-, gamma- and delta-tocopherols were not toxic to either cell type up to 40 microM. In BEC, confluent cell density was decreased by all concentrations of delta- and gamma-tocopherol (10-40 microM) but not by alpha-tocopherol. LEC showed no change in cell density in response to tocopherols. delta-Tocopherol (40 microM), but not other isomers, decreased BEC invasiveness. In LEC, all doses of gamma-tocopherol, as well as the highest dose of alpha-tocopherol (40 microM), decreased cell invasiveness. delta-Tocopherol had no effect on LEC invasiveness at any molarity. delta-Tocopherol dose dependently increased cell permeability at 48 h in BEC and LEC; alpha- and gamma-tocopherols showed slight effects. Capillary tube formation was decreased by high dose (40 microM) concentrations of alpha-, gamma- and delta-tocopherol, but showed no effects with smaller doses (10-20 microM) in BEC. gamma-Tocopherol (10-20 microM) and alpha-tocopherol (10 microM), but not delta-tocopherol, increased LEC capillary tube formation. Lastly, in BEC, alpha-, gamma- and delta-tocopherol each dose-dependently reduced TNF-alpha-induced expression of VCAM-1. In LEC, there was no significant change to TNF-alpha-induced VCAM-1 expression with any concentration of alpha-, gamma- or delta-tocopherol. These data demonstrate that physiological levels (0-40 microM) of alpha-, gamma- and delta-tocopherols are nontoxic and dietary tocopherols, especially delta

  11. Estimated Effect of Epoetin Dosage on Survival among Elderly Hemodialysis Patients in the United States

    OpenAIRE

    Zhang, Yi; Thamer, Mae; Cotter, Dennis; Kaufman, James; Hernán, Miguel A.

    2009-01-01

    Background and objectives: The common finding that low achieved hemoglobin in observational studies and high target hemoglobin in randomized trials each were associated with increased mortality and high epoetin dosage has suggested the possibility that high epoetin dosage might explain the increased mortality risk.

  12. Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta

    DEFF Research Database (Denmark)

    Yan, Zhen Cheng; Liu, Dao Yan; Zhang, Li Li

    2007-01-01

    Obesity is one major cardiovascular risk factor. We tested effects of endurance exercise on cannabinoid receptor type 1 (CB1) and peroxisome proliferator-activated receptor-delta (PPAR-delta)-dependent pathways in adipose tissue. Male Wistar rats were randomly assigned to standard laboratory chow...... or a high-fat diet without and with regular endurance exercise. Exercise in rats on high-fat diet significantly reduced visceral fat mass, blood pressure, and adipocyte size (each p...

  13. How much are biosimilars used in southern Italy?: a retrospective analysis of epoetin utilization in the local health unit of Messina in the years 2010-2011.

    Science.gov (United States)

    Loiacono, Chiara; Sgroi, Carmela; Coppolino, Salvatore; Cannata, Angelo; Ferrara, Rosarita; Arcoraci, Vincenzo; Cananzi, Pasquale; Savica, Vincenzo; Schuemie, Martijn; Caputi, Achille P; Trifirò, Gianluca

    2012-04-01

    Epoetins are one of the three biologics for which biosimilars are available in Italy. So far, there is a lack of Italian national/regional longitudinal data about epoetin use. The aim of this study was to evaluate the prescribing pattern of epoetins (reference products and biosimilars) in a Local Health Unit (LHU) of Southern Italy in recent years. A retrospective drug utilization study was conducted during the period 1 January 2010 - 31 May 2011. The data source was the dispensing database of the Messina LHU, which contains anonymized data about dispensed drugs (including epoetins) that are prescribed by specialists to the residents in the catchment area. Indication of use and prescribed dosage of epoetins were derived by the therapeutic plans filled in by specialists and linked to drug dispensing records. Prevalence of epoetin use in the province of Messina (653 810 inhabitants) in 2010 was calculated. Furthermore, frequency analyses by sex, age, indication of use of epoetin users, as well as measurement of volume of use (defined daily dose [DDD]/1000/day) and expenditure of epoetins in 2010 were also performed. Analysis of the switching pattern between different reference products and biosimilar epoetins was performed. Overall, 4288 patients were treated with epoetins during the study period (mean age  ± SD: 74.2 ± 13.7; females: 52%). Darbepoetin alpha and reference product epoetin alpha accounted overall for 79.8% of epoetin users, while biosimilars of epoetin alpha accounted for 0.9%. Among 1247 epoetin users for whom the therapeutic plan was revised, 1065 (85.4%) were treated because of anemia due to chronic kidney disease and 158 (12.6%) because of chemotherapy-induced anemia. In 2010, prevalence of epoetin use was 5.5 (95% CI 5.3, 5.7) per 1000 inhabitants in the province of Messina. The volume of use and related expenditure for epoetins was 3.58 DDD/1000 inhabitants/day and Euro 5 572 457 (about Euro 8.50 per capita/day) in 2010. Switching

  14. CMV seropositivity determines epoetin dose and hemoglobin levels in patients with CKD

    NARCIS (Netherlands)

    M.G.H. Betjes (Michiel); W. Weimar (Willem); N.H.R. Litjens (Nicolle)

    2009-01-01

    textabstractCytomegalovirus (CMV)-seropositive patients with ESRD may have more CD4+T cells lacking the co-stimulatory molecule CD28 (CD4+CD28null) than CMV-seronegative patients. Increased numbers of CD28null T cells associates with epoetin nonresponsiveness in patients with ESRD, but whether

  15. Fluvial sediment supply to a mega-delta reduced by shifting tropical-cyclone activity.

    Science.gov (United States)

    Darby, Stephen E; Hackney, Christopher R; Leyland, Julian; Kummu, Matti; Lauri, Hannu; Parsons, Daniel R; Best, James L; Nicholas, Andrew P; Aalto, Rolf

    2016-11-10

    The world's rivers deliver 19 billion tonnes of sediment to the coastal zone annually, with a considerable fraction being sequestered in large deltas, home to over 500 million people. Most (more than 70 per cent) large deltas are under threat from a combination of rising sea levels, ground surface subsidence and anthropogenic sediment trapping, and a sustainable supply of fluvial sediment is therefore critical to prevent deltas being 'drowned' by rising relative sea levels. Here we combine suspended sediment load data from the Mekong River with hydrological model simulations to isolate the role of tropical cyclones in transmitting suspended sediment to one of the world's great deltas. We demonstrate that spatial variations in the Mekong's suspended sediment load are correlated (r = 0.765, P sediment load reaching the delta is delivered by runoff generated by rainfall associated with tropical cyclones. Furthermore, we estimate that the suspended load to the delta has declined by 52.6 ± 10.2 megatonnes over recent years (1981-2005), of which 33.0 ± 7.1 megatonnes is due to a shift in tropical-cyclone climatology. Consequently, tropical cyclones have a key role in controlling the magnitude of, and variability in, transmission of suspended sediment to the coast. It is likely that anthropogenic sediment trapping in upstream reservoirs is a dominant factor in explaining past, and anticipating future, declines in suspended sediment loads reaching the world's major deltas. However, our study shows that changes in tropical-cyclone climatology affect trends in fluvial suspended sediment loads and thus are also key to fully assessing the risk posed to vulnerable coastal systems.

  16. An Approach to Coordinate Efforts to Reduce the Public Health Burden of Stroke: The Delta States Stroke Consortium

    OpenAIRE

    Virginia J. Howard; Joe Acker; Camilo R. Gomez; Ada H. Griffies; Wanda Magers; Max Michael III; Sean R. Orr; Martha Phillips; James M. Raczynski; John E. Searcy; Richard M. Zweifler; George Howard

    2004-01-01

    Stroke is the third leading cause of death and a leading cause of disability in the United States, with a particularly high burden on the residents of the southeastern states, a region dubbed the Stroke Belt. These five states Alabama, Arkansas, Louisiana, Mississippi, and Tennessee have formed the Delta States Stroke Consortium to direct efforts to reduce this burden. The consortium is proposing an approach to identify domains where interventions may be instituted and an array of activitie...

  17. C and Si delta doping in Ge by CH_3SiH_3 using reduced pressure chemical vapor deposition

    International Nuclear Information System (INIS)

    Yamamoto, Yuji; Ueno, Naofumi; Sakuraba, Masao; Murota, Junichi; Mai, Andreas; Tillack, Bernd

    2016-01-01

    C and Si delta doping in Ge are investigated using a reduced pressure chemical vapor deposition system to establish atomic-order controlled processes. CH_3SiH_3 is exposed at 250 °C to 500 °C to a Ge on Si (100) substrate using H_2 or N_2 carrier gas followed by a Ge cap layer deposition. At 350 °C, C and Si are uniformly adsorbed on the Ge surface and the incorporated C and Si form steep delta profiles below detection limit of SIMS measurement. By using N_2 as carrier gas, the incorporated C and Si doses in Ge are saturated at one mono-layer below 350 °C. At this temperature range, the incorporated C and Si doses are nearly the same, indicating CH_3SiH_3 is adsorbed on the Ge surface without decomposing the C−Si bond. On the other hand, by using H_2 as carrier gas, lower incorporated C is observed in comparison to Si. CH_3SiH_3 injected with H_2 carrier gas is adsorbed on Ge without decomposing the C−Si bond and the adsorbed C is reduced by dissociation of the C−Si bond during temperature ramp up to 550 °C. The adsorbed C is maintained on the Ge surface in N_2 at 550 °C. - Highlights: • C and Si delta doping in Ge is investigated using RPCVD system by CH_3SiH_3 exposure. • Atomically flat C and Si delta layers are fabricated at 350 °C. • Incorporated C and Si doses are saturated at one mono-layer below 350 °C. • CH_3SiH_3 adsorption occurred without decomposing C−Si bond. • Adsorbed C is desorbed due to dissociation by hydrogen during postannealing at 550 °C.

  18. Dgroup: DG00177 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available DG00177 Chemical ... DGroup Erythropoietin ... D03231 ... Epoetin alfa (USAN/INN); Epoetin... alfa (genetical recombination) (JP17) ... D03232 ... Epoetin beta (USAN/INN); Epoetin beta (genetical recombina...tion) (JP17) ... D04032 ... Epoetin delta (USAN) D09737 ... Epoetin kappa (INN); Epoetin kappa (genetical recombination) (Epoet...in alfa biosimilar 1) (JAN) ... D09998 ... Epoetin beta pegol (genetical ...recombination) (JAN) ... D10000 ... Epoetin epsilon (INN); Epoetin epsilon (genetical recombination) (JAN) D10846 ... Epoet

  19. Reduced genetic distance and high replication levels increase the RNA recombination rate of hepatitis delta virus.

    Science.gov (United States)

    Lin, Chia-Chi; Yang, Zhi-Wei; Iang, Shan-Bei; Chao, Mei

    2015-01-02

    Hepatitis delta virus (HDV) replication is carried out by host RNA polymerases. Since homologous inter-genotypic RNA recombination is known to occur in HDV, possibly via a replication-dependent process, we hypothesized that the degree of sequence homology and the replication level should be related to the recombination frequency in cells co-expressing two HDV sequences. To confirm this, we separately co-transfected cells with three different pairs of HDV genomic RNAs and analyzed the obtained recombinants by RT-PCR followed by restriction fragment length polymorphism and sequencing analyses. The sequence divergence between the clones ranged from 24% to less than 0.1%, and the difference in replication levels was as high as 100-fold. As expected, significant differences were observed in the recombination frequencies, which ranged from 0.5% to 47.5%. Furthermore, varying the relative amounts of parental RNA altered the dominant recombinant species produced, suggesting that template switching occurs frequently during the synthesis of genomic HDV RNA. Taken together, these data suggest that during the host RNA polymerase-driven RNA recombination of HDV, both inter- and intra-genotypic recombination events are important in shaping the genetic diversity of HDV. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. Randomized double-blind clinical trial of a new human epoetin versus a commercially available formula for anemia control in patients on hemodialysis

    Directory of Open Access Journals (Sweden)

    Paulo D. Picon

    2014-08-01

    Full Text Available OBJECTIVES: Anemia is a common complication among chronic kidney disease patients on hemodialysis, occurring mostly due to erythropoietin deficiency. This randomized noninferiority trial sought to compare the efficacy and safety of a new epoetin formulation developed by Bio-Manguinhos, a biologics manufacturer affiliated with the Brazilian government, with those of a commercially available product currently used in Brazil (a biosimilar epoetin formulation. METHODS: The sample size needed to enable demonstration of noninferiority with a statistical power of 85% for a between-group difference in hemoglobin levels of no more than 1.5 g/dL was calculated. In total, 74 patients were randomly assigned to receive the epoetin formulation from Bio-Manguinhos (n = 36 or the biosimilar epoetin formulation (n = 38 in a double-blind fashion. The inclusion criteria were current epoetin therapy and stable hemoglobin levels for at least 3 months prior to the study. The primary and secondary outcomes were mean monthly hemoglobin levels and safety, respectively. The dose was calculated according to international criteria and adjusted monthly in both groups according to hemoglobin levels and at the assistant physicians' discretion. Iron storage was estimated at baseline and once monthly. Clinicaltrials.gov: NCT01184495. RESULTS: The study was conducted for 6 months after randomization. The mean baseline hemoglobin levels were 10.9±1.2 and 10.96±1.2 g/dL (p = 0.89 in the Bio-Manguinhos epoetin and biosimilar epoetin groups, respectively. During the study period, there was no significant change in hemoglobin levels in either group (p = 0.055, ANOVA. The epoetin from Bio-Manguinhos was slightly superior in the last 3 months of follow-up. The adverse event profiles of the two formulations were also similar. CONCLUSIONS: The epoetin formulations tested in this study are equivalent in efficacy and safety.

  1. Activation of PPAR{delta} up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic {beta}-cells

    Energy Technology Data Exchange (ETDEWEB)

    Wan, Jun; Jiang, Li; Lue, Qingguo; Ke, Linqiu [Department of Endocrinology, West China Hospital of Sichuan University, 37 Guoxue Lane, Chengdu, Sichuan 610041 (China); Li, Xiaoyu [State Key Laboratory of Oral Diseases, Sichuan University, No. 14, 3rd Section, Renmin South Road, Chengdu, Sichuan 610041 (China); Tong, Nanwei, E-mail: buddyjun@hotmail.com [Department of Endocrinology, West China Hospital of Sichuan University, 37 Guoxue Lane, Chengdu, Sichuan 610041 (China)

    2010-01-15

    Recent evidence indicates that decreased oxidative capacity, lipotoxicity, and mitochondrial aberrations contribute to the development of insulin resistance and type 2 diabetes. The goal of this study was to investigate the effects of peroxisome proliferator-activated receptor {delta} (PPAR{delta}) activation on lipid oxidation, mitochondrial function, and insulin secretion in pancreatic {beta}-cells. After HIT-T15 cells (a {beta}-cell line) were exposed to high concentrations of palmitate and GW501516 (GW; a selective agonist of PPAR{delta}), we found that administration of GW increased the expression of PPAR{delta} mRNA. GW-induced activation of PPAR{delta} up-regulated carnitine palmitoyltransferase 1 (CPT1), long-chain acyl-CoA dehydrogenase (LCAD), pyruvate dehydrogenase kinase 4 (PDK4), and uncoupling protein 2 (UCP2); alleviated mitochondrial swelling; attenuated apoptosis; and reduced basal insulin secretion induced by increased palmitate in HIT cells. These results suggest that activation of PPAR{delta} plays an important role in protecting pancreatic {beta}-cells against aberrations caused by lipotoxicity in metabolic syndrome and diabetes.

  2. Epoetin zeta in the management of anemia associated with chronic kidney disease, differential pharmacology and clinical utility

    Directory of Open Access Journals (Sweden)

    Davis-Ajami ML

    2014-04-01

    Full Text Available Mary Lynn Davis-Ajami,1 Jun Wu,2 Katherine Downton,3 Emilie Ludeman,3 Virginia Noxon4 1Organizational Systems and Adult Health, University of Maryland School of Nursing, Baltimore, MD, USA; 2South Carolina College of Pharmacy, University of South Carolina, Greenville, SC, USA; 3Health Sciences and Human Services Library, University of Maryland, Baltimore, MD, USA; 4Department of Clinical Pharmacy and Outcomes Science, South Carolina College of Pharmacy, University of South Carolina, Columbia, SC, USA Abstract: Epoetin zeta was granted marketing authorization in October 2007 by the European Medicines Agency as a recombinant human erythropoietin erythropoiesis-stimulating agent to treat symptomatic anemia of renal origin in adult and pediatric patients on hemodialysis and adults on peritoneal dialysis, as well as for symptomatic renal anemia in adult patients with renal insufficiency not yet on dialysis. Currently, epoetin zeta can be administered either subcutaneously or intravenously to correct for hemoglobin concentrations ≤10 g/dL (6.2 mmol/L or with dose adjustment to maintain hemoglobin levels at desired levels not in excess of 12 g/dL (7.5 mmol/L. This review article focuses on epoetin zeta indications in chronic kidney disease, its use in managing anemia of renal origin, and discusses its pharmacology and clinical utility. Keywords: biosimilar, chronic kidney disease, epoetin alfa, erythropoiesis, renal anemia, Retacrit®

  3. Efficacy and safety of once-weekly intravenous epoetin alfa in maintaining hemoglobin levels in hemodialysis patients.

    Science.gov (United States)

    Locatelli, Francesco; Villa, Giuseppe; Messa, Piergiorgio; Filippini, Armando; Cannella, Giuseppe; De Ferrari, Giacomo; Naso, Agostino; Rossi, Egidio; Formica, Marco; Lombardi, Luigi; Rotolo, Ugo; Conte, Feruccio

    2008-01-01

    Although an erythropoiesis-stimulating agent (ESA) is most frequently administered intravenously for treatment of anemia in patients with chronic kidney disease who are on dialysis, few studies have compared the efficacy of different intravenous (i.v.) dosing schedules. This multicenter, phase IIIb, open-label, controlled study randomized 289 stable hemodialysis patients to continue with conventional dosing of i.v. epoetin alfa or darbepoetin, or to switch to once-weekly i.v. epoetin alfa at the same cumulative weekly starting dose, to maintain hemoglobin levels at 11.0-13.0 g/dL, and within 1.0 g/dL of the baseline value. Hemoglobin levels and ESA doses were recorded every 4 weeks for 28 weeks. Hemoglobin levels fell significantly and ESA doses increased significantly between baseline and week 28 (mean of week 16-28 values) in the once-weekly epoetin alfa group, compared with the conventional treatment group (phemoglobin levels between the groups was 0.73 g/dL (greater than the threshold for therapeutic equivalence of 0.5 g/dL). The changes between groups from baseline was significant at all time points for hemoglobin levels (0.36, 0.46, 0.81, 0.87, 0.78, 0.62 and 0.49 g/dL) and from week 12 for ESA dose (718.5, 1,326.5, 1,732.0, 1,839.7 and 1,959.1 IU/week; p=0.005). Hemoglobin was maintained at the target level in 78% and 84% of patients on conventional dosing, and 67% and 64% of those on once-weekly epoetin alfa in the intention-to-treat (p=0.1) and per protocol (p=0.016) populations, respectively. This study did not show therapeutic equivalence of once-weekly i.v. epoetin alfa with conventional dosing regimens.

  4. Methoxy polyethylene glycol-epoetin beta for the treatment of anemia associated with chronic renal failure.

    Science.gov (United States)

    Schmid, Holger

    2016-01-01

    Since more than two decades erythropoiesis-stimulating agents are the main pillar for treatment of anemia associated with chronic kidney disease. Methoxy polyethylene glycol-epoetin beta (MPG-EPO), also called continuous erythropoietin receptor activator, is the longest acting erythropoiesis-stimulating agent currently available. MPG-EPO is characterized by an elimination half-life of approximately 137 h and offers extended dosing intervals up to 4 weeks. Numerous phase I/II studies and a comprehensive clinical phase III program demonstrated the feasibility of MPG-EPO therapy for anemia correction and maintenance of stable hemoglobin levels in adult chronic kidney disease patients. Due to patent disputes MPG-EPO was only available outside the US market so far. In view of a prevailing US market introduction, this review focuses on efficacy and safety data from pivotal trials, summarizes recent clinical research and finally tries to substantiate potential benefits associated with the use of this anti-anemic drug.

  5. Effect of occasional epoetin use in combination with a stable darbepoetin dosage on anemia management in hemodialysis patients

    Directory of Open Access Journals (Sweden)

    Shimamatsu K

    2014-12-01

    Full Text Available Kazumasa Shimamatsu Shimamatsu Naika Iin (Clinic, Shiseikai Medical Corporation, Chikushino City, Japan Aim: Taking advantage of the characteristics of both darbepoetin (DA and epoetin (EPO might be a reasonable option for stabilizing hemoglobin (Hb control in hemodialysis (HD patients. The effect of DA assisted by EPO (DA/EPO on Hb control was evaluated retrospectively in comparison with that of EPO monotherapy. Methods: Twenty-six HD patients whose annual mean Hb values were available for both an EPO monotherapy period and a DA/EPO period were selected for analysis. During the DA/EPO period, DA was given on the second HD day of a week, and EPO was given if needed on the first and third HD days. Under stable DA dosage, when Hb rose >12 g/dL, EPO was eliminated. When Hb decreased <10 g/dL, EPO was added again. The variability of annual mean Hb values from the 26 HD patients during the DA/EPO period was compared with that during the EPO period. Additionally, the distance in Hb (d-Hb; absolute value of difference between the annual mean Hb values and the target Hb (11 g/dL during the DA/EPO period was compared with that during the EPO period. Results: The variability of annual mean Hb values during the DA/EPO period was significantly smaller than that during the EPO period (11.2±0.25 g/dL versus [vs] 11.0±0.50 g/dL; the F-test for equality of variance, P<0.001. Additionally, the d-Hb during the DA/EPO period was significantly smaller than that during the EPO period (0.22±0.21 g/dL vs 0.38±0.31 g/dL, P<0.03. The total doses (as EPO equivalents of DA with EPO were reduced to 82.2% of the baseline EPO dose during the EPO monotherapy period. The expenditure for the DA/EPO period was significantly reduced to 80.9% of that for the EPO monotherapy. Also, the annual total amount of intravenous iron supplementation during the DA/EPO period was significantly reduced compared with that during the EPO period (546±304 mg/year vs 684±314 mg/year, P<0

  6. Vitamin-E reduces the oxidative damage on delta-aminolevulinic dehydratase induced by lead intoxication in rat erythrocytes.

    Science.gov (United States)

    Rendón-Ramirez, A; Cerbón-Solórzano, J; Maldonado-Vega, M; Quintanar-Escorza, M A; Calderón-Salinas, J V

    2007-09-01

    Lead intoxication induces oxidative damage on lipids and proteins. In the present paper we study in vivo and in vitro the antioxidant effect of vitamin-E and trolox, on the oxidative effects of lead intoxication in rat erythrocytes. Vitamin-E simultaneously administered to erythrocytes treated with lead was capable to prevent the inhibition of delta-aminolevulinic dehydratase activity and lipid oxidation. Partial but important protective effects were found when vitamin-E was administered either after or before lead exposure in rats. In vitro, the antioxidant trolox protected delta-ALA-D activity against damage induced by lead or menadione. These results indicate that vitamin-E could be useful in order to protect membrane-lipids and, notably, to prevent protein oxidation produced by lead intoxication.

  7. C and Si delta doping in Ge by CH{sub 3}SiH{sub 3} using reduced pressure chemical vapor deposition

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Yuji, E-mail: yamamoto@ihp-microelectronics.com [IHP, Im Technologiepark 25, 15236 Frankfurt (Oder) (Germany); Ueno, Naofumi; Sakuraba, Masao [Laboratory for Nanoelectronics and Spintronics, Research Institute of Electrical Communication, Tohoku University, 2-1-1, Katahira, Aoba-Ku, Sendai 980-8577 (Japan); Murota, Junichi [Micro System Integration Center, Tohoku University, 519-1176, Aramaki aza Aoba, Aoba-ku, Sendai 980-0845 (Japan); Mai, Andreas [IHP, Im Technologiepark 25, 15236 Frankfurt (Oder) (Germany); Tillack, Bernd [IHP, Im Technologiepark 25, 15236 Frankfurt (Oder) (Germany); Technische Universität Berlin, HFT4, Einsteinufer 25, 10587 Berlin (Germany)

    2016-03-01

    C and Si delta doping in Ge are investigated using a reduced pressure chemical vapor deposition system to establish atomic-order controlled processes. CH{sub 3}SiH{sub 3} is exposed at 250 °C to 500 °C to a Ge on Si (100) substrate using H{sub 2} or N{sub 2} carrier gas followed by a Ge cap layer deposition. At 350 °C, C and Si are uniformly adsorbed on the Ge surface and the incorporated C and Si form steep delta profiles below detection limit of SIMS measurement. By using N{sub 2} as carrier gas, the incorporated C and Si doses in Ge are saturated at one mono-layer below 350 °C. At this temperature range, the incorporated C and Si doses are nearly the same, indicating CH{sub 3}SiH{sub 3} is adsorbed on the Ge surface without decomposing the C−Si bond. On the other hand, by using H{sub 2} as carrier gas, lower incorporated C is observed in comparison to Si. CH{sub 3}SiH{sub 3} injected with H{sub 2} carrier gas is adsorbed on Ge without decomposing the C−Si bond and the adsorbed C is reduced by dissociation of the C−Si bond during temperature ramp up to 550 °C. The adsorbed C is maintained on the Ge surface in N{sub 2} at 550 °C. - Highlights: • C and Si delta doping in Ge is investigated using RPCVD system by CH{sub 3}SiH{sub 3} exposure. • Atomically flat C and Si delta layers are fabricated at 350 °C. • Incorporated C and Si doses are saturated at one mono-layer below 350 °C. • CH{sub 3}SiH{sub 3} adsorption occurred without decomposing C−Si bond. • Adsorbed C is desorbed due to dissociation by hydrogen during postannealing at 550 °C.

  8. Delta Dynamics

    DEFF Research Database (Denmark)

    Bendixen, Mette

    . The warming air temperature affects the soil temperature and permafrost thaws and destabilizes the material in the coastal zone. In Greenland, the warming temperature lowers the surface mass balance of the Greenland Ice Sheet and more material is transported to the coastal zone. The sea ice extent is thinning...... of a fjord and the second type is a wider fan-shaped open delta. Most deltas are directly coupled to the Greenland Ice Sheet or local icecaps and are highly influenced by the dynamics in the catchments. It is demonstrated how a modern changing climate directly affects delta dynamics, and that Greenlandic...... deltas are prograding, contrary to the global trend showing eroding Arctic coasts. Moreover, it is revealed that the increasing proglacial freshwater runoff, caused by a lowering of the surface mass balance of the Greenland Ice Sheet is the main determining agent in delta progradation. The final part...

  9. Epoetin alfa improves anemia and anemia-related, patient-reported outcomes in patients with breast cancer receiving myelotoxic chemotherapy: Results of a european, multicenter, randomized, controlled trial

    NARCIS (Netherlands)

    P. Pronzato (Paolo); E. Cortesi (Enrico); C.C.D. van der Rijt (Carin); A. Bols (Alain); J.A. Moreno-Nogueira (José); C.F. de Oliveira; P. Barrett-Lee (Peter); P.J. Ostler (Peter); R. Rosso (Ricardo)

    2010-01-01

    textabstractPurpose. To evaluate the effects of epoetin alfa on patient- reported outcomes (PROs) in patients with breast cancer receiving myelotoxic chemotherapy. Materials and Methods. Women with hemoglobin concentrations ≤12.0 g/dl and an Eastern Cooperative Oncology Group performance status

  10. Twice-monthly administration of a lower dose of epoetin beta pegol can maintain adequate hemoglobin levels in hemodialysis patients.

    Science.gov (United States)

    Morikami, Yuki; Fujimori, Akira; Okada, Shioko; Kumei, Mai; Mizobuchi, Noriko; Sakai, Makoto

    2015-04-01

    Epoetin beta pegol is a continuous erythropoietin receptor activator (CERA) with a long half-life. Although CERA has been shown to maintain adequate hemoglobin (Hb) levels at prolonged dosing intervals, the optimal dosing schedule remains unclear. We therefore compared the efficacy of maintaining hemoglobin levels with administration of twice-monthly CERA (TWICE) versus once-monthly CERA (ONCE). Twenty hemodialysis patients receiving epoetin beta (EPO) were enrolled in this crossover study. Patients were assigned to either the TWICE or the ONCE group based on matching Hb levels and EPO doses. After 6 months of treatment, the CERA dosage was interchanged between the groups and the study was continued for an additional 6 months. The effect of the different regimens on iron metabolism was also assessed during the first 6 months of the study. Hb levels significantly increased in the TWICE group, allowing for a reduction in CERA dosage, while the dose of CERA required to maintain Hb levels in the ONCE group remained unchanged. After the interchange, a decrease in Hb levels with incremental increase in CERA dosage was observed in the TWICE→ONCE group, with the opposite effect observed in the ONCE→TWICE group. Although increases in ferritin and hepcidin-25 levels in the ONCE group were noted at one month, they disappeared at 6 months. Although Hb levels were maintained in both the ONCE and TWICE groups, a twice-monthly administration was advantageous, as it required a lower dose of CERA. © 2014 The Authors. Therapeutic Apheresis and Dialysis © 2014 International Society for Apheresis.

  11. Epoetin alfa 40000 U once weekly and intravenous iron supply in solid tumor patients: early increase of hemoglobin level during chemotherapy

    International Nuclear Information System (INIS)

    Lalle, M.; Antimi, M.; Pistillucci, G.; D'Aprile, M.

    2005-01-01

    The objective of this observational study was the early evaluation of the impact, a week after the first administration of epoetin alfa 40000 U once weekly and i.v. dose of 62.5 mg sodium ferric gluconate for seven days in improving hemoglobin levels in cancer patients affected by mild/moderate or severe anemia during chemotherapy. Twenty patients affected by solid tumors who received epoetin alfa 40000 U once weekly and daily i.v. sodium ferric gluconate for one week were evaluated: 90% of the patients showed hemoglobin increase, with a median level of hemoglobin increase of 0.73 g/L from baseline, and 50% of them showing a hemoglobin increase > 1 gr/L. The treatment was well tolerated and no adverse event was observed. The early increase of hemoglobin level from baseline is interesting and suggestive for the possibility of achieving an adequate hemoglobin level with a short-term treatment. It is still necessary to further explore the real need of iron supplementation to maintain adequate erythropoiesis prior and during epoetin therapy

  12. COMMD1 regulates the delta epithelial sodium channel ({delta}ENaC) through trafficking and ubiquitination

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Tina; Ke, Ying; Ly, Kevin [Department of Physiology, University of Otago, P.O. Box 913, Dunedin 9054 (New Zealand); McDonald, Fiona J., E-mail: fiona.mcdonald@otago.ac.nz [Department of Physiology, University of Otago, P.O. Box 913, Dunedin 9054 (New Zealand)

    2011-08-05

    Highlights: {yields} The COMM domain of COMMD1 mediates binding to {delta}ENaC. {yields} COMMD1 reduces the cell surface population of {delta}ENaC. {yields} COMMD1 increases the population of {delta}ENaC-ubiquitin. {yields} Both endogenous and transfected {delta}ENaC localize with COMMD1 and transferrin suggesting they are located in early/recycling endosomes. -- Abstract: The delta subunit of the epithelial sodium channel ({delta}ENaC) is a member of the ENaC/degenerin family of ion channels. {delta}ENaC is distinct from the related {alpha}-, {beta}- and {gamma}ENaC subunits, known for their role in sodium homeostasis and blood pressure control, as {delta}ENaC is expressed in brain neurons and activated by external protons. COMMD1 (copper metabolism Murr1 domain 1) was previously found to associate with and downregulate {delta}ENaC activity. Here, we show that COMMD1 interacts with {delta}ENaC through its COMM domain. Co-expression of {delta}ENaC with COMMD1 significantly reduced {delta}ENaC surface expression, and led to an increase in {delta}ENaC ubiquitination. Immunocytochemical and confocal microscopy studies show that COMMD1 promoted localization of {delta}ENaC to the early/recycling endosomal pool where the two proteins were localized together. These results suggest that COMMD1 downregulates {delta}ENaC activity by reducing {delta}ENaC surface expression through promoting internalization of surface {delta}ENaC to an intracellular recycling pool, possibly via enhanced ubiquitination.

  13. Future Change to Tide-Influenced Deltas

    Science.gov (United States)

    Nienhuis, Jaap H.; Hoitink, A. J. F. (Ton); Törnqvist, Torbjörn E.

    2018-04-01

    Tides tend to widen deltaic channels and shape delta morphology. Here we present a predictive approach to assess a priori the effect of fluvial discharge and tides on deltaic channels. We show that downstream channel widening can be quantified by the ratio of the tide-driven discharge and the fluvial discharge, along with a second metric representing flow velocities. A test of our new theory on a selection of 72 deltas globally shows good correspondence to a wide range of environments, including wave-dominated deltas, river-dominated deltas, and alluvial estuaries. By quantitatively relating tides and fluvial discharge to delta morphology, we offer a first-order prediction of deltaic change that may be expected from altered delta hydrology. For example, we expect that reduced fluvial discharge in response to dam construction will lead to increased tidal intrusion followed by enhanced tide-driven sediment import into deltas, with implications for navigation and other human needs.

  14. Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon® and Eprex® following a single subcutaneous administration in healthy male volunteers

    Directory of Open Access Journals (Sweden)

    Yoon S

    2017-10-01

    Full Text Available Sumin Yoon,1 Su-jin Rhee,1 Sun Ju Heo,2 Tae Young Oh,2 Seo Hyun Yoon,1 Joo-Youn Cho,1 SeungHwan Lee,1,3 Kyung-Sang Yu1,3 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, 2Dong-A ST Co. Ltd., Seoul, 3Clinical Trials Center, Seoul National University Hospital, Seoul, Republic of Korea Purpose: This study aimed to assess and compare the pharmacokinetic (PK and pharmacodynamic (PD properties following a single subcutaneous injection of epoetin alfa (Eporon® with those of the comparator (Eprex® in healthy male subjects. Subjects and methods: A randomized, double-blind, two-sequence, crossover study was conducted. Subjects were randomly assigned to receive a single dose, that is, 4,000 IU, of the test or comparator epoetin alfa. After 4 weeks, all subjects received the alternative formulation. The primary PK parameters, maximum observed concentration (Cmax and area under the curve extrapolated to infinity (AUCinf, were calculated with the serum erythropoietin (EPO concentrations from blood samples collected for 144 h after dosing. The reticulocyte, hematocrit, hemoglobin and red blood cell counts were measured up to 312 h as PD markers. The primary PD parameters, maximum observed effect (Emax and area under the effect curve (AUEC, were obtained from the baseline-corrected reticulocyte count. The serum EPO concentration and the reticulocyte count were used to assess the concentration–response relationship. The tolerability and immunogenicity profiles were assessed together. Results: Forty-two subjects completed the study. The mean EPO concentration–time profiles were comparable between the two formulations. The geometric mean ratios (90% CI of the Cmax and AUCinf were 0.908 (0.843–0.978 and 1.049 (0.999–1.101, respectively, both of which were within the regulatory range of 0.80–1.25. Additionally, the PD and tolerability profiles were similar between the two

  15. Delta inulin-derived adjuvants that elicit Th1 phenotype following vaccination reduces respiratory syncytial virus lung titers without a reduction in lung immunopathology.

    Science.gov (United States)

    Wong, Terianne M; Petrovsky, Nikolai; Bissel, Stephanie J; Wiley, Clayton A; Ross, Ted M

    2016-08-02

    Respiratory syncytial virus (RSV) is a significant cause of lower respiratory tract infections resulting in bronchiolitis and even mortality in the elderly and young children/infants. Despite the impact of this virus on human health, no licensed vaccine exists. Unlike many other viral infections, RSV infection or vaccination does not induce durable protective antibodies in humans. In order to elicit high titer, neutralizing antibodies against RSV, we investigated the use of the adjuvant Advax™, a novel polysaccharide adjuvant based on delta inulin microparticles, to enhance antibody titers following vaccination. BALB/c mice were vaccinated intramuscularly with live RSV as a vaccine antigen in combination with one of two formulations of Advax™. Advax-1 was comprised of the standard delta inulin adjuvant and Advax-2 was formulated delta inulin plus CpG oligodendronucleotides (ODNs). An additional group of mice were either mock vaccinated, immunized with vaccine only, or administered vaccine plus Imject Alum. Following 3 vaccinations, mice had neutralizing antibody titers that correlated with reduction in viral titers in the lungs. Advax-1 significantly enhanced serum RSV-specific IgG1 levels at week 6 indicative of a Th2 response, similar to titers in mice administered vaccine plus Imject Alum. In contrast, mice vaccinated with vaccine plus Advax-2 had predominately IgG2a titers indicative of a Th1 response that was maintained during the entire study. Interestingly, regardless of which Advax TM adjuvant was used, the neutralizing titers were similar between groups, but the viral lung titers were significantly lower (∼10E+3pfu/g) in mice administered vaccine with either Advax TM adjuvant compared to mice administered adjuvants only. The lung pathology in vaccinated mice with Advax TM was similar to Imject Alum. Overall, RSV vaccine formulated with Advax TM had high neutralizing antibody titers with low lung viral titers, but exacerbated lung pathology compared

  16. Tides Stabilize Deltas until Humans Interfere

    Science.gov (United States)

    Hoitink, T.; Zheng Bing, W.; Vermeulen, B.; Huismans, Y.; Kastner, K.

    2017-12-01

    Despite global concerns about river delta degradation caused by extraction of natural resources, sediment retention by reservoirs and sea-level rise, human activity in the world's largest deltas intensifies. In this review, we argue that tides tend to stabilize deltas until humans interfere. Under natural circumstances, delta channels subject to tides are more stable than their fluvial-dominated counterparts. The oscillatory tidal flow counteracts the processes responsible for bank erosion, which explains why unprotected tidal channels migrate only slowly. Peak river discharges attenuate the tides, which creates storage space to accommodate the extra river discharge during extreme events and as a consequence, reduce flood risk. With stronger tides, the river discharge is being distributed more evenly over the various branches in a delta, preventing silting up of smaller channels. Human interference in deltas is massive. Storm surge barriers are constructed, new land is being reclaimed and large-scale sand excavation takes place, to collect building material. Evidence from deltas around the globe shows that in human-controlled deltas the tidal motion often plays a destabilizing role. In channels of the Rhine-Meuse Delta, some 100 scour holes are identified, which relates to the altered tidal motion after completion of a storm surge barrier. Sand mining has led to widespread river bank failures in the tidally-influenced Mekong Delta. The catastrophic flood event in the Gauges-Brahmaputra Delta by Cyclone Aila, which caused the inundation of an embanked polder area for over two years, was preceded by river bank erosion at the mouths of formal tidal channels that were blocked by the embankment. Efforts to predict the developments of degrading deltas are few. Existing delta models are capable of reproducing expanding deltas, which is essentially a matter of simulating the transport of sediment from source in a catchment to the sink in a delta. Processes of soil

  17. Epoetin beta pegol ameliorates flow-mediated dilation with improving endothelial nitric oxide synthase coupling state in nonobese diabetic rats.

    Science.gov (United States)

    Serizawa, Kenichi; Yogo, Kenji; Tashiro, Yoshihito; Kawasaki, Ryohei; Endo, Koichi; Shimonaka, Yasushi; Hirata, Michinori

    2017-04-01

    Patients with diabetic nephropathy have a high cardiovascular mortality. Epoetin beta pegol (continuous erythropoietin receptor activator, C.E.R.A.) is a drug for the treatment of renal anemia. In this study, we investigated the effect of C.E.R.A. on vascular endothelial function as evaluated by flow-mediated dilation (FMD) and the relationship between hematopoiesis and FMD in diabetic nephropathy rats. Male Spontaneously Diabetic Torii rats (SDT, 22 weeks old) were used. C.E.R.A. (0.6, 1.2 μg/kg) was administered subcutaneously once every 2 weeks for 8 weeks. At 1 week after last administration (31 weeks old), we assessed FMD in the femoral arteries of anesthetized rats using a high-resolution ultrasound system. FMD was also measured 1 week after single C.E.R.A. treatment (5.0 μg/kg) to examine the influence of hematopoiesis. Flow-mediated dilation was significantly decreased in SDT rats before the start of C.E.R.A. treatment (22 weeks old). Repeated administration of C.E.R.A. dose-dependently improved FMD in SDT rats (31 weeks old) without changing blood glucose, nitroglycerin-induced vasodilation, or kidney function. Long-term administration of C.E.R.A. improved the state of endothelial nitric oxide synthase uncoupling in the femoral arteries of SDT rats, which showed a positive correlation with FMD. On the other hand, there was no correlation between FMD and Hb or Hct in SDT rats. Furthermore, at 1 week after single administration of C.E.R.A., FMD was not significantly improved although hemoglobin levels were comparable with levels following long-term C.E.R.A. Long-term treatment with C.E.R.A. improved FMD in SDT rats even after onset of endothelial dysfunction. © 2017 The Authors. Cardiovascular Therapeutics Published by John Wiley & Sons Ltd.

  18. Delta Plaza kohvik = Delta Plaza cafe

    Index Scriptorium Estoniae

    2010-01-01

    Tallinnas Pärnu mnt 141 asuva kohviku Delta Plaza sisekujundusest. Sisearhitektid Tiiu Truus ja Marja Viltrop (Stuudio Truus OÜ). Tiiu Truusi tähtsamate tööde loetelu. Büroohoone Delta Plaza arhitektid Marika Lõoke ja Jüri Okas (AB J. Okas & M. Lõoke)

  19. delta-vision

    Data.gov (United States)

    California Natural Resource Agency — Delta Vision is intended to identify a strategy for managing the Sacramento-San Joaquin Delta as a sustainable ecosystem that would continue to support environmental...

  20. Antiferromagnetic ordering in reduced Al doped YBa2Cu3-xAlxO6+#delta# single crystals

    DEFF Research Database (Denmark)

    Brecht, E.; Casalta, H.; Schleger, P.

    1994-01-01

    In YBa2Cu3-AlxO6+delta single crystals antiferromagnetic AFII ordering has been observed below 18 K by neutron diffraction. The transition temperature T-2 to the AFI ordering increases with x and delta.......In YBa2Cu3-AlxO6+delta single crystals antiferromagnetic AFII ordering has been observed below 18 K by neutron diffraction. The transition temperature T-2 to the AFI ordering increases with x and delta....

  1. Rise and Fall of one of World's largest deltas; the Mekong delta in Vietnam

    Science.gov (United States)

    Minderhoud, P. S. J.; Eslami Arab, S.; Pham, H. V.; Erkens, G.; van der Vegt, M.; Oude Essink, G.; Stouthamer, E.; Hoekstra, P.

    2017-12-01

    The Mekong delta is the third's largest delta in the world. It is home to almost 20 million people and an important region for the food security in South East Asia. As most deltas, the Mekong delta is the dynamic result of a balance of sediment supply, sea level rise and subsidence, hosting a system of fresh and salt water dynamics. Ongoing urbanization, industrialization and intensification of agricultural practices in the delta, during the past decades, resulted in growing domestic, agricultural and industrial demands, and have led to a dramatic increase of fresh water use. Since the year 2000, the amount of fresh groundwater extracted from the subsurface increased by 500%. This accelerated delta subsidence as the groundwater system compacts, with current sinking rates exceeding global sea level rise up to an order of magnitude. These high sinking rates have greatly altered the sediment budget of the delta and, with over 50% of the Mekong delta surface elevated less than 1 meter above sea level, greatly increase vulnerability to flooding and storm surges and ultimately, permanent inundation. Furthermore, as the increasingly larger extractions rapidly reduce the fresh groundwater reserves, groundwater salinization subsequently increases. On top of that, dry season low-flows by the Mekong river cause record salt water intrusion in the delta's estuarine system, creating major problems for rice irrigation. We present the work of three years research by the Dutch-Vietnamese `Rise and Fall' project on land subsidence and salinization in both groundwater and surface water in the Vietnamese Mekong delta.

  2. DELTA 3D PRINTER

    Directory of Open Access Journals (Sweden)

    ȘOVĂILĂ Florin

    2016-07-01

    Full Text Available 3D printing is a very used process in industry, the generic name being “rapid prototyping”. The essential advantage of a 3D printer is that it allows the designers to produce a prototype in a very short time, which is tested and quickly remodeled, considerably reducing the required time to get from the prototype phase to the final product. At the same time, through this technique we can achieve components with very precise forms, complex pieces that, through classical methods, could have been accomplished only in a large amount of time. In this paper, there are presented the stages of a 3D model execution, also the physical achievement after of a Delta 3D printer after the model.

  3. Delta antibody radioimmunoassay

    Energy Technology Data Exchange (ETDEWEB)

    Kselikova, M; Urbankova, J

    1985-11-15

    The principle and procedure are described of the radioimmunoassay of delta antibody (delta-Ab) using the ABBOTT ANTI-DELTA kit by Abbott Co. A description is given of the kit, the working procedure and the method of evaluation. The results are reported of the incidence of delta-Ab in sera of patients with viral hepatitis B, in haemophiliacs, carriers of the hepatitis B virus surface antigen (HBsAg) and blood donors. The presence was detected of delta-Ab in one HBsAg carrier. The necessity is emphasized of delta-Ab determinations in the blood of donors in view of the antibody transfer with blood and blood preparations.

  4. Epoetin Alfa Injection

    Science.gov (United States)

    ... cannot be used to treat pregnant or nursing women or babies. The single use vials do not contain benzyl alcohol and may be used to treat pregnant or nursing women or babies, but they are only safe to ...

  5. Delta hedging strategies comparison

    DEFF Research Database (Denmark)

    De Giovanni, Domenico; Ortobelli, S.; Rachev, S.T.

    2008-01-01

    In this paper we implement dynamic delta hedging strategies based on several option pricing models. We analyze different subordinated option pricing models and we examine delta hedging costs using ex-post daily prices of S&P 500. Furthermore, we compare the performance of each subordinated model...

  6. Connectivity in river deltas

    Science.gov (United States)

    Passalacqua, P.; Hiatt, M. R.; Sendrowski, A.

    2016-12-01

    Deltas host approximately half a billion people and are rich in ecosystem diversity and economic resources. However, human-induced activities and climatic shifts are significantly impacting deltas around the world; anthropogenic disturbance, natural subsidence, and eustatic sea-level rise are major causes of threat to deltas and in many cases have compromised their safety and sustainability, putting at risk the people that live on them. In this presentation, I will introduce a framework called Delta Connectome for studying connectivity in river deltas based on different representations of a delta as a network. Here connectivity indicates both physical connectivity (how different portions of the system interact with each other) as well as conceptual (pathways of process coupling). I will explore several network representations and show how quantifying connectivity can advance our understanding of system functioning and can be used to inform coastal management and restoration. From connectivity considerations, the delta emerges as a leaky network that evolves over time and is characterized by continuous exchanges of fluxes of matter, energy, and information. I will discuss the implications of connectivity on delta functioning, land growth, and potential for nutrient removal.

  7. Growth laws for sub-delta crevasses in the Mississippi River Delta

    Science.gov (United States)

    Yocum, T. A.; Georgiou, I. Y.; Straub, K. M.

    2017-12-01

    River deltas are threatened by environmental change, including subsidence, global sea level rise, reduced sediment inputs and other local factors. In the Mississippi River Delta (MRD) these impacts are exemplified, and have led to proposed solutions to build land that include sediment diversions to reinitiate the delta cycle. Deltas were studied extensively using numerical models, theoretical and conceptual frameworks, empirical scaling relationships, laboratory models and field observations. But predicting the future of deltas relies on field observations where for most deltas data are still lacking. Moreover, empirical and theoretical scaling laws may be influenced by the data used to develop them, while laboratory deltas may be influenced by scaling issues. Anthropogenic crevasses in the MRD are large enough to overcome limitations of laboratory deltas, and small enough to allow for rapid channel and wetland development, providing an ideal setting to investigate delta development mechanics. Here we assessed growth laws of sub-delta crevasses (SDC) in the MRD, in two experimental laboratory deltas (LD - weakly and strongly cohesive) and compared them to river dominated deltas worldwide. Channel and delta geometry metrics for each system were obtained using geospatial tools, bathymetric datasets, sediment size, and hydrodynamic observations. Results show that SDC follow growth laws similar to large river dominated deltas, with the exception of some that exhibit anomalous behavior with respect to the frequency and distance to a bifurcation and the fraction of wetted delta shoreline (allometry metrics). Most SDC exhibit a systematic decrease of non-dimensional channel geometries with increased bifurcation order, indicating that channels are adjusting to decreased flow after bifurcations occur, and exhibit linear trends for land allometry and width-depth ratio, although geometries decrease more rapidly per bifurcation order. Measured distance to bifurcations in SDC

  8. Fast delta Hadamard transform

    International Nuclear Information System (INIS)

    Fenimore, E.E.; Weston, G.S.

    1981-01-01

    In many fields (e.g., spectroscopy, imaging spectroscopy, photoacoustic imaging, coded aperture imaging) binary bit patterns known as m sequences are used to encode (by multiplexing) a series of measurements in order to obtain a larger throughput. The observed measurements must be decoded to obtain the desired spectrum (or image in the case of coded aperture imaging). Decoding in the past has used a technique called the fast Hadamard transform (FHT) whose chief advantage is that it can reduce the computational effort from N 2 multiplies of N log 2 N additions or subtractions. However, the FHT has the disadvantage that it does not readily allow one to sample more finely than the number of bits used in the m sequence. This can limit the obtainable resolution and cause confusion near the sample boundaries (phasing errors). Both 1-D and 2-D methods (called fast delta Hadamard transforms, FDHT) have been developed which overcome both of the above limitations. Applications of the FDHT are discussed in the context of Hadamard spectroscopy and coded aperture imaging with uniformly redundant arrays. Special emphasis has been placed on how the FDHT can unite techniques used by both of these fields into the same mathematical basis

  9. The Niger Delta Crisis

    African Journals Online (AJOL)

    chifaou.amzat

    2013-09-28

    Sep 28, 2013 ... Department of History & International Studies, Delta State University, Abraka,. Nigeria. .... democracy implies popular power. That is ... Okonta (2006:5) draws attention to Anna Zalik's treatise called 'Petro-Vio- lence' and ...

  10. Delta agent (Hepatitis D)

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000216.htm Hepatitis D (Delta agent) To use the sharing features on this page, please enable JavaScript. Hepatitis D is a viral infection caused by the ...

  11. Delta 2.0

    DEFF Research Database (Denmark)

    Skott, Jeppe; Skott, Charlotte Krog; Jess, Kristine

    DELTA 2.0 er en ny og helt opdateret udgave af Delta, der i ti år været brugt i matematiklærernes grund-, efter- og videreuddannelse. DELTA 2.0 er seriens almene fagdidaktik. Der er også fagdidaktiske overvejelser i de øvrige bøger i serien, men de er knyttet til specifikt matematisk indhold. DELTA...... 2.0 behandler mere generelle matematikdidaktiske problemstillinger såsom læringsteoretiske overvejelser i forbindelse med matematik, centrale aspekter af det at undervise i matematik og digitale teknologier som værktøj til at støtte elevers faglige læring af matematik....

  12. Remote stereocontrol by sulfinyl groups: reduction of delta-ketosulfoxides.

    Science.gov (United States)

    García Ruano, José L; Fernández-Ibáñez, M Angeles; Maestro, M Carmen; Rodríguez-Fernández, M Mercedes

    2005-03-04

    The reduction of delta-ketosulfoxides constitutes the first evidence of the efficiency of the sulfinyl group to control the stereoselectivity of 1,5-asymmetric induction processes. The use of DIBAL/Yb(OTf)3 or L-Selectride as the reducing agents provides delta-hydroxysulfoxides with the opposite configuration at the hydroxylic carbon in a highly stereoselective way.

  13. Potential cost saving of Epoetin alfa in elective hip or knee surgery due to reduction in blood transfusions and their side effects: a discrete-event simulation model.

    Directory of Open Access Journals (Sweden)

    Jörg Tomeczkowski

    Full Text Available OBJECTIVES: Transfusion of allogeneic blood is still common in orthopedic surgery. This analysis evaluates from the perspective of a German hospital the potential cost savings of Epoetin alfa (EPO compared to predonated autologous blood transfusions or to a nobloodconservationstrategy (allogeneic blood transfusion strategyduring elective hip and knee replacement surgery. METHODS: Individual patients (N = 50,000 were simulated based on data from controlled trials, the German DRG institute (InEK and various publications and entered into a stochastic model (Monte-Carlo of three treatment arms: EPO, preoperative autologous donation and nobloodconservationstrategy. All three strategies lead to a different risk for an allogeneic blood transfusion. The model focused on the costs and events of the three different procedures. The costs were obtained from clinical trial databases, the German DRG system, patient records and medical publications: transfusion (allogeneic red blood cells: €320/unit and autologous red blood cells: €250/unit, pneumonia treatment (€5,000, and length of stay (€300/day. Probabilistic sensitivity analyses were performed to determine which factors had an influence on the model's clinical and cost outcomes. RESULTS: At acquisition costs of €200/40,000 IU EPO is cost saving compared to autologous blood donation, and cost-effective compared to a nobloodconservationstrategy. The results were most sensitive to the cost of EPO, blood units and hospital days. CONCLUSIONS: EPO might become an attractive blood conservation strategy for anemic patients at reasonable costs due to the reduction in allogeneic blood transfusions, in the modeled incidence of transfusion-associated pneumonia andthe prolongedlength of stay.

  14. Potential cost saving of Epoetin alfa in elective hip or knee surgery due to reduction in blood transfusions and their side effects: a discrete-event simulation model.

    Science.gov (United States)

    Tomeczkowski, Jörg; Stern, Sean; Müller, Alfred; von Heymann, Christian

    2013-01-01

    Transfusion of allogeneic blood is still common in orthopedic surgery. This analysis evaluates from the perspective of a German hospital the potential cost savings of Epoetin alfa (EPO) compared to predonated autologous blood transfusions or to a nobloodconservationstrategy (allogeneic blood transfusion strategy)during elective hip and knee replacement surgery. Individual patients (N = 50,000) were simulated based on data from controlled trials, the German DRG institute (InEK) and various publications and entered into a stochastic model (Monte-Carlo) of three treatment arms: EPO, preoperative autologous donation and nobloodconservationstrategy. All three strategies lead to a different risk for an allogeneic blood transfusion. The model focused on the costs and events of the three different procedures. The costs were obtained from clinical trial databases, the German DRG system, patient records and medical publications: transfusion (allogeneic red blood cells: €320/unit and autologous red blood cells: €250/unit), pneumonia treatment (€5,000), and length of stay (€300/day). Probabilistic sensitivity analyses were performed to determine which factors had an influence on the model's clinical and cost outcomes. At acquisition costs of €200/40,000 IU EPO is cost saving compared to autologous blood donation, and cost-effective compared to a nobloodconservationstrategy. The results were most sensitive to the cost of EPO, blood units and hospital days. EPO might become an attractive blood conservation strategy for anemic patients at reasonable costs due to the reduction in allogeneic blood transfusions, in the modeled incidence of transfusion-associated pneumonia andthe prolongedlength of stay.

  15. Women of Niger Delta

    African Journals Online (AJOL)

    Religion Dept

    The Indispensability of Women in Conflict Resolution in the Niger Delta ... The situation leads to a shift in gender roles with a dramatic increase in the number of women .... organization is to work in partnership with the Nigerian Government and the .... that “women are the impartial arbitrators in family or clan disputes or.

  16. Conservative Delta Hedging

    Science.gov (United States)

    1997-09-01

    an exact method for converting such intervals into arbitrage based prices of financial derivatives or industrial or contractual options. We call this...procedure conservative delta hedging . As existing procedures are of an ad hoc nature, the proposed approach will permit an institution’s man agement a greater oversight of its exposure to risk.

  17. Mystery of the delta(980)

    International Nuclear Information System (INIS)

    Cahn, R.N.; Landshoff, P.V.

    1986-01-01

    The apparent conflict between the dominance of the decay delta->etaπ in D->deltaπ and its absence in iota->deltaπ is analyzed. Explicit models are presented in which the nearby Kanti K threshold plays an important role in resolving the conflict. (orig.)

  18. Climate change and the Delta

    Science.gov (United States)

    Dettinger, Michael; Anderson, Jamie; Anderson, Michael L.; Brown, Larry R.; Cayan, Daniel; Maurer, Edwin P.

    2016-01-01

    Anthropogenic climate change amounts to a rapidly approaching, “new” stressor in the Sacramento–San Joaquin Delta system. In response to California’s extreme natural hydroclimatic variability, complex water-management systems have been developed, even as the Delta’s natural ecosystems have been largely devastated. Climate change is projected to challenge these management and ecological systems in different ways that are characterized by different levels of uncertainty. For example, there is high certainty that climate will warm by about 2°C more (than late-20th-century averages) by mid-century and about 4°C by end of century, if greenhouse-gas emissions continue their current rates of acceleration. Future precipitation changes are much less certain, with as many climate models projecting wetter conditions as drier. However, the same projections agree that precipitation will be more intense when storms do arrive, even as more dry days will separate storms. Warmer temperatures will likely enhance evaporative demands and raise water temperatures. Consequently, climate change is projected to yield both more extreme flood risks and greater drought risks. Sea level rise (SLR) during the 20th century was about 22cm, and is projected to increase by at least 3-fold this century. SLR together with land subsidence threatens the Delta with greater vulnerabilities to inundation and salinity intrusion. Effects on the Delta ecosystem that are traceable to warming include SLR, reduced snowpack, earlier snowmelt and larger storm-driven streamflows, warmer and longer summers, warmer summer water temperatures, and water-quality changes. These changes and their uncertainties will challenge the operations of water projects and uses throughout the Delta’s watershed and delivery areas. Although the effects of climate change on Delta ecosystems may be profound, the end results are difficult to predict, except that native species will fare worse than invaders. Successful

  19. DELTAS: A new Global Delta Sustainability Initiative (Invited)

    Science.gov (United States)

    Foufoula-Georgiou, E.

    2013-12-01

    Deltas are economic and environmental hotspots, food baskets for many nations, home to a large part of the world population, and hosts of exceptional biodiversity and rich ecosystems. Deltas, being at the land-water interface, are international, regional, and local transport hubs, thus providing the basis for intense economic activities. Yet, deltas are deteriorating at an alarming rate as 'victims' of human actions (e.g. water and sediment reduction due to upstream basin development), climatic impacts (e.g. sea level rise and flooding from rivers and intense tropical storms), and local exploration (e.g. sand or aggregates, groundwater and hydrocarbon extraction). Although many efforts exist on individual deltas around the world, a comprehensive global delta sustainability initiative that promotes awareness, science integration, data and knowledge sharing, and development of decision support tools for an effective dialogue between scientists, managers and policy makers is lacking. Recently, the international scientific community proposed to establish the International Year of Deltas (IYD) to serve as the beginning of such a Global Delta Sustainability Initiative. The IYD was proposed as a year to: (1) increase awareness and attention to the value and vulnerability of deltas worldwide; (2) promote and enhance international and regional cooperation at the scientific, policy, and stakeholder level; and (3) serve as a launching pad for a 10-year committed effort to understand deltas as complex socio-ecological systems and ensure preparedness in protecting and restoring them in a rapidly changing environment. In this talk, the vision for such an international coordinated effort on delta sustainability will be presented as developed by a large number of international experts and recently funded through the Belmont Forum International Opportunities Fund. Participating countries include: U.S., France, Germany, U.K., India, Japan, Netherlands, Norway, Brazil, Bangladesh

  20. Inventory Management in Delta Allied Wire Industries Limited Asaba ...

    African Journals Online (AJOL)

    A good inventory system reduces production cost and consequently increases profit. Optimum management of inventory in the Delta – Allied Wire Industries ... under review and customers' handling processes equally studied for improvement.

  1. Sediment and Vegetation Controls on Delta Channel Networks

    Science.gov (United States)

    Lauzon, R.; Murray, A. B.; Piliouras, A.; Kim, W.

    2016-12-01

    Numerous factors control the patterns of distributary channels formed on a delta, including water and sediment discharge, grain size, sea level rise rates, and vegetation type. In turn, these channel networks influence the shape and evolution of a delta, including what types of plant and animal life - such as humans - it can support. Previous fluvial modeling and flume experiments, outside of the delta context, have addressed how interactions between sediment and vegetation, through their influence on lateral transport of sediment, determine what type of channel networks develops. Similar interactions likely also shape delta flow patterns. Vegetation introduces cohesion, tending to reduce channel migration rates and strengthen existing channel banks, reinforcing existing channels and resulting in localized, relatively stable flow patterns. On the other hand, sediment transport processes can result in lateral migration and frequent switching of active channels, resulting in flow resembling that of a braided stream. While previous studies of deltas have indirectly explored the effects of vegetation through the introduction of cohesive sediment, we directly incorporate key effects of vegetation on flow and sediment transport into the delta-building model DeltaRCM to explore how these effects influence delta channel network formation. Model development is informed by laboratory flume experiments at UT Austin. Here we present initial results of experiments exploring the effects of sea level rise rate, sediment grain size, vegetation type, and vegetation growth rate on delta channel network morphology. These results support the hypothesis that the ability for lateral transport of sediment to occur plays a key role in determining the evolution of delta channel networks and delta morphology.

  2. In vivo metabolism of the methyl homologues of delta-8-tetrahydrocannabinol, delta-9-tetrahydrocannabinol and abn-delta-8-tetrahydrocannabinol in the mouse.

    Science.gov (United States)

    Brown, N K; Harvey, D J

    1988-04-01

    Methyl-delta-8-tetrahydrocannabinol (methyl-delta-8-THC), methyl-delta-9-THC and abn-methyl-delta-8-THC were synthesized by condensation of orcinol and (1S)-cis-verbenol and were administered to male Charles River CD-1 mice. Extracted hepatic metabolites were isolated by chromatography on Sephadex LH-20 and examined by gas chromatography/mass spectrometry as trimethylsilyl (TMS), (2H9)TMS and methyl ester/TMS derivatives. In addition, metabolic fractions were reduced with lithium aluminium deuteride to convert carboxylic acids to alcohols for structural correlation. Metabolites from methyl-delta-8-THC were similar with respect to the positions substituted to those produced by higher homologues; the major metabolite was methyl-delta-8-THC-11-oic acid. abn-Methyl-delta-8-THC was metabolized in a different manner. The location of the aromatic methyl group at the position adjacent to ring fusion appeared to inhibit metabolism at C(11) to a considerable extent and also to reduce the amount of the resulting alcohol from being oxidized to a carboxylic acid. This caused other metabolic pathways to become dominant, with the result that a compound containing a hydroxy group at the gem-methyl position was the major metabolite. Hydroxylation at this position has not been confirmed with any other cannabinoid, although it is thought to result in trace concentrations of hydroxy metabolites from some compounds. Metabolism of methyl-delta-9-THC was also similar to that of the higher homologues, with the exception that less metabolism occurred at C(8) and a higher percentage of the total metabolic fraction was accounted for by the 11-oic acid metabolite. Minor metabolites were mainly dihydroxy compounds and hydroxylated derivatives of delta-9-THC-11-oic acid.

  3. Thermostatted delta f

    International Nuclear Information System (INIS)

    Krommes, J.A.

    2000-01-01

    The delta f simulation method is revisited. Statistical coarse-graining is used to rigorously derive the equation for the fluctuation delta f in the particle distribution. It is argued that completely collisionless simulation is incompatible with the achievement of true statistically steady states with nonzero turbulent fluxes because the variance of the particle weights w grows with time. To ensure such steady states, it is shown that for dynamically collisionless situations a generalized thermostat or W-stat may be used in lieu of a full collision operator to absorb the flow of entropy to unresolved fine scales in velocity space. The simplest W-stat can be implemented as a self-consistently determined, time-dependent damping applied to w. A precise kinematic analogy to thermostatted nonequilibrium molecular dynamics (NEMD) is pointed out, and the justification of W-stats for simulations of turbulence is discussed. An extrapolation procedure is proposed such that the long-time, steady-state, collisionless flux can be deduced from several short W-statted runs with large effective collisionality, and a numerical demonstration is given

  4. People of the Delta

    Energy Technology Data Exchange (ETDEWEB)

    Gregoire, L.

    2007-09-15

    The potential impacts of both global warming and the $16 billion Mackenzie pipeline project on communities in the Mackenzie Delta were discussed. A consortium of oil and gas developers is now planning to exploit the natural gas reserves located near the mouth of the Delta, whose largest town is Inuvik. The project is expected to place a significant burden on the resources and infrastructure of the town, which currently has a population of 6000. The community, comprised of a diverse international population and an Inuit majority, is largely in favour of the pipeline project. The Inuvialuit people have invested a significant amount of time to ensure that the project, which was stalled due to land claims in 1977, benefits their communities. Public hearings are now being held to consider the potential environmental and socio-economic impacts of the project. Separate hearings are also being held to consider the project's design. The pipeline project includes 3 natural gas production facilities, a gas-processing facility, a pipeline gathering system, a 480 km natural gas liquids pipeline to the Northwest Territories, and a 1220 km natural gas pipeline to northern Alberta. The pipeline will be buried to minimize environmental impacts. The project is expected to create 8200 jobs at the height of its construction. However, communities located near the site of the natural gas reserves, such as the town of Tuktoyaktuk are now threatened by soil erosion that has been attributed to global warming. 21 figs.

  5. Phenotypic expressions of CCR5-Delta 32/Delta 32 homozygosity

    NARCIS (Netherlands)

    Nguyen, GT; Carrington, M; Beeler, JA; Dean, M; Aledort, LM; Blatt, PM; Cohen, AR; DiMichele, D; Eyster, ME; Kessler, CM; Konkle, B; Leissinger, C; Luban, N; O'Brien, SJ; Goedert, JJ; O'Brien, TR

    1999-01-01

    Objective: As blockade of CC-chemokine receptor 5 (CCR5) has been proposed as therapy for HIV-1, we examined whether the CCR5-Delta 32/Delta 32 homozygous genotype has phenotypic expressions other than those related to HIV-1. Design: Study subjects were white homosexual men or men with hemophilia

  6. Peat compaction in deltas : implications for Holocene delta evolution

    NARCIS (Netherlands)

    van Asselen, S.

    2010-01-01

    Many deltas contain substantial amounts of peat, which is the most compressible soil type. Therefore, peat compaction potentially leads to high amounts of subsidence in deltas. The main objective of this research was to quantify subsidence due to peat compaction in Holocene fluvial-deltaic settings

  7. Challenges, Approaches and Experiences from Asian Deltas and the Rhine-Meuse Delta : Regional Training Workshop on Delta Planning and Management

    NARCIS (Netherlands)

    Wosten, J.H.M.; Douven, W.; Long Phi, H.; Fida Abdullah Khan, M.

    2013-01-01

    River delta's, like the Mekong Delta (Vietnam), Ganges-Brahmaputra Delta (Bangladesh), Ayeyarwady Delta (Myanmar), Nile (Egypt) and Ciliwung Delta (Indonesia) are developing rapidly and are characterised by large-scale urbanisation and industrialization processes. They are facing serious planning

  8. Mida pakub Delta? / Teele Kurm

    Index Scriptorium Estoniae

    Kurm, Teele

    2011-01-01

    Politsei- ja Piirivalveamet võtab kasutusele ühise Siseministeeriumi infotehnoloogia- ja arenduskeskuse ning Webmedia AS koostööna loodud dokumendihaldussüsteemi Delta. Kust sai Delta oma nime? Projekti "Dokumendihaldussüsteemi juurutamine Siseministeeriumi haldusalas" eesmärgid

  9. Stimulation of accumbal GABAA receptors inhibits delta2-, but not delta1-, opioid receptor-mediated dopamine efflux in the nucleus accumbens of freely moving rats.

    Science.gov (United States)

    Aono, Yuri; Kiguchi, Yuri; Watanabe, Yuriko; Waddington, John L; Saigusa, Tadashi

    2017-11-15

    The nucleus accumbens contains delta-opioid receptors that may reduce inhibitory neurotransmission. Reduction in GABA A receptor-mediated inhibition of accumbal dopamine release due to delta-opioid receptor activation should be suppressed by stimulating accumbal GABA A receptors. As delta-opioid receptors are divided into delta2- and delta1-opioid receptors, we analysed the effects of the GABA A receptor agonist muscimol on delta2- and delta1-opioid receptor-mediated accumbal dopamine efflux in freely moving rats using in vivo microdialysis. Drugs were administered intracerebrally through the dialysis probe. Doses of compounds indicate total amount administered (mol) during 25-50min infusions. The delta2-opioid receptor agonist deltorphin II (25.0nmol)- and delta1-opioid receptor agonist DPDPE (5.0nmol)-induced increases in dopamine efflux were inhibited by the delta2-opioid receptor antagonist naltriben (1.5nmol) and the delta1-opioid receptor antagonist BNTX (150.0pmol), respectively. Muscimol (250.0pmol) inhibited deltorphin II (25.0nmol)-induced dopamine efflux. The GABA A receptor antagonist bicuculline (50.0pmol), which failed to affect deltorphin II (25.0nmol)-induced dopamine efflux, counteracted the inhibitory effect of muscimol on deltorphin II-induced dopamine efflux. Neither muscimol (250.0pmol) nor bicuculline (50.0 and 500.0pmol) altered DPDPE (5.0nmol)-induced dopamine efflux. The present results show that reduction in accumbal GABA A receptor-mediated inhibition of dopaminergic activity is necessary to produce delta2-opioid receptor-induced increase in accumbal dopamine efflux. This study indicates that activation of delta2- but not delta1-opioid receptors on the cell bodies and/or terminals of accumbal GABAergic interneurons inhibits GABA release and, accordingly, decreases GABA A receptor-mediated inhibition of dopaminergic terminals, resulting in enhanced accumbal dopamine efflux. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Delta isobars in neutron stars

    Directory of Open Access Journals (Sweden)

    Pagliara Giuseppe

    2015-01-01

    Full Text Available The appearance of delta isobars in beta-stable matter is regulated by the behavior of the symmetry energy at densities larger than saturation density. We show that by taking into account recent constraints on the density derivative of the symmetry energy and the theoretical and experimental results on the excitations of delta isobars in nuclei, delta isobars are necessary ingredients for the equations of state used for studying neutron stars. We analyze the effect of the appearance of deltas on the structure of neutron stars: as in the case of hyperons, matter containing delta is too soft for allowing the existence of 2M⊙ neutron stars. Quark stars on the other hand, could reach very massive configurations and they could form from a process of conversion of hadronic stars in which an initial seed of strangeness appears through hyperons.

  11. Environmental Risk Profiling of the Volta Delta, Ghana

    Science.gov (United States)

    Nyarko, B. K.; Appeaning-Addo, K.; Amisigo, B.

    2017-12-01

    Volta Delta communities find it difficult to absorb or bear risk at different levels, because of the physical and economic impacts of environmental hazards. In this regards various agencies and organizations have in recent years launched initiatives to measure and identify risk areas with a set of indicators and indices. The theory underpinning this study is concepts of Modern Portfolio Theory (MPT). The Cox proportional hazards regression model will be used as the model for the risk profile. Finding the optimal level of environmental risk for activities in the Volta Delta considering the risk required, risk capacity and risk tolerance. Using data from different sources, an environmental risk profile was developed for the Volta Delta. The result indicates that risks are distributed across the Delta. However, areas that have government interventions, such as sea defense system and irrigation facilities have less threat. In addition wealthy areas do effectively reduce the threat of any form of disaster.

  12. [Position statements regarding usage of biosimilars of Epoetins. Position paper of the Société de néphrologie, Société francophone de dialyse, and Société de néphrologie pédiatrique].

    Science.gov (United States)

    Bouchet, Jean-Louis; Brunet, Philippe; Canaud, Bernard; Chanliau, Jacques; Combe, Christian; Deray, Gilbert; Houillier, Pascal; Kourilsky, Olivier; Ledneva, Elena; Niaudet, Patrick; Ortiz, Jean-Paul; Pavlovic, Mira; Ryckelynck, Jean-Philippe; Singlas, Eric; Verhelst, David

    2009-02-01

    The European patents for epoetin alpha recently expired. Biosimilars (i.e. "a medicine which is similar to a biological medicine that has already been authorized" [EMEA 2007]) of epoetins have thus been released on the market in Europe. Because of the complexity of the processes that are required to produce medicinal products containing biotechnology-derived proteins as active substances and to characterize the physicochemical properties of these compounds, the guidelines that have been developed for generic drugs cannot be used for approval of biosimilar products. The EMEA guidelines do not answer all questions that have been raised for the development of biosimilars, and in some cases, decisions will have to be taken at a national level. This is why the Society of Nephrology (Société de néphrologie), the French-speaking Society of Dialysis (Société francophone de dialyse) and the Pediatric Society of Nephrology (Société de néphrologie pédiatrique) established guidelines for the usage of biosimilar epoetins concerning approval, identification, substitution of an innovator drug, post-marketing surveillance, extension of indication and pharmacovigilance plan.

  13. Delta Evolution at Røde Elv, Disko Island, Greenland

    Science.gov (United States)

    Kroon, A.; Arngrimson, J.; Bendixen, M.; Sigsgaard, C.

    2017-12-01

    Ice, snow and freezing temperatures have a large impact on coastal morphodynamics in Arctic polar environments. A recent warming of the Arctic climate induces many changes along the arctic shorelines. Sea-levels are rising due to thermal expansion and due to an increased fresh water flux from the glaciers and land ice masses. At the same time, the ice coverage of the coastal waters reduces and the open water periods in summer extend. There is a strong seasonal variation with open waters and active rivers in summer and ice-covered coastal waters and inactive rivers in winter. Coastal processes by waves and tides are thus limited to the summer and early fall. Besides, there is also a strong daily variation in fluvial discharges due to the daily variations in glacier melt with maximum melt in the afternoon and minimum values at night. At the same time, the actual flux of the river to the coastal bay is influenced by the tidal phase. Low tides will enhance the transport to the delta front, while high tides will create stagnant waters over the delta plain. The delta of the Røde Elv is located in southwestern Disko Island in west Greenland. It has a relatively small (ca. 101 km2) and partly glaciated drainage basin (ca. 20%) and its sediments consist of a mixture of basaltic sands and gravels. The Røde Elv delta is located at the end of a pro-glacial and fluvial valley at about 20 km from the glacier. The shores of the delta are reworked by waves, predominantly from southwestern, southern (largest fetch, over 50 km), and southeastern directions. The environment has a micro- to meso- tidal range with a spring tidal range of 2.7 m. The morphologic changes on the delta over the last decades clearly showed a seaward extension of the delta and a periodic shift in the location of the main delta channel. In this presentation, we focus on quantification of water discharges and suspended sediment fluxes to the Røde Elv delta in western Greenland, and on the morphological

  14. Energy deposition by delta rays

    International Nuclear Information System (INIS)

    Weigand, F.C.; Braby, L.A.

    1983-01-01

    Monte Carlo calculations for proton tracks were extended to projectile with more complex electronic structures which add additional delta ray production processes. An experimental apparatus was used to detect gas gain and resolution for H 2+ and 3 He ++

  15. Niger Delta Development Commission and Sustainable ...

    African Journals Online (AJOL)

    Niger Delta Development Commission and Sustainable Development of Niger Delta Region of Nigeria: The Case of Rivers State. Goddey Wilson. Abstract. The study is on Niger Delta Development Commission and sustainable development of Niger Delta region of Nigeria, the case of Rivers State. The main objective of the ...

  16. $\\delta$-Expansion at Finite Temperature

    OpenAIRE

    Ramos, Rudnei O.

    1996-01-01

    We apply the $\\delta$-expansion perturbation scheme to the $\\lambda \\phi^{4}$ self-interacting scalar field theory in 3+1 D at finite temperature. In the $\\delta$-expansion the interaction term is written as $\\lambda (\\phi^{2})^{ 1 + \\delta}$ and $\\delta$ is considered as the perturbation parameter. We compute within this perturbative approach the renormalized mass at finite temperature at a finite order in $\\delta$. The results are compared with the usual loop-expansion at finite temperature.

  17. Anaerobic Transformation of Furfural by Methanococcus deltae (Delta)LH

    Science.gov (United States)

    Belay, N.; Boopathy, R.; Voskuilen, G.

    1997-01-01

    Methanococcus deltae (Delta)LH was grown on H(inf2)-CO(inf2) in the presence of various concentrations of furfural. Furfural at higher concentrations, namely, 20 and 25 mM, inhibited growth of this organism. At concentration of 5 and 10 mM, no inhibition of growth was observed. The other methanogens in this study were not inhibited by 10 mM furfural. Among the methanogens tested, M. deltae was capable of transforming furfural, whereas Methanobacterium thermoautotrophicum Marburg, Methanosarcina barkeri 227, Methanococcus thermolithotrophicus, and Methanobrevibacter ruminantium lacked this capability. One hundred percent removal of furfural was observed within 48 h of incubation in M. deltae cultures. The end product observed during furfural metabolism was furfuryl alcohol. An almost stoichiometric amount of furfuryl alcohol was produced by M. deltae. This transformation is likely to be of value in the detoxification of furfural and in its ultimate conversion to methane and CO(inf2) by anaerobic digestion. PMID:16535618

  18. Delta smelt: Life history and decline of a once abundant species in the San Francisco Estuary

    Science.gov (United States)

    Moyle, Peter B.; Brown, Larry R.; Durand, John R; Hobbs, James A.

    2016-01-01

    This paper reviews what has been learned about Delta Smelt and its status since the publication of The State of Bay-Delta Science, 2008 (Healey et al. 2008). The Delta Smelt is endemic to the upper San Francisco Estuary. Much of its historic habitat is no longer available and remaining habitat is increasingly unable to sustain the population. As a listed species living in the central node of California’s water supply system, Delta Smelt has been the focus of a large research effort to understand causes of decline and identify ways to recover the species. Since 2008, a remarkable record of innovative research on Delta Smelt has been achieved, which is summarized here. Unfortunately, research has not prevented the smelt’s continued decline, which is the result of multiple, interacting factors. A major driver of decline is change to the Delta ecosystem from water exports, resulting in reduced outflows and high levels of entrainment in the large pumps of the South Delta. Invasions of alien species, encouraged by environmental change, have also played a contributing role in the decline. Severe drought effects have pushed Delta Smelt to record low levels in 2014–2015. The rapid decline of the species and failure of recovery efforts demonstrate an inability to manage the Delta for the “co-equal goals” of maintaining a healthy ecosystem and providing a reliable water supply for Californians. Diverse and substantial management actions are needed to preserve Delta Smelt.

  19. Biomass co-firing for Delta Electricity

    International Nuclear Information System (INIS)

    Anon

    2014-01-01

    Electricity generator Delta Electricity has implemented a biomass co-firing program at its Vales Point power station on the Central Coast to reduce its reliance on coal and emissions of CO 2 . The program comprises two parts: direct co-firing with coal of up to 5% biomass; and development of Continuous Biomass Converter (CBC) technology with the Crucible Group to remove technology constraints and enable much higher rates of biomass co-firing. It is talking industrial scale tests. Delta increased biomass co-firing in 2013/14 to 32,000 tonnes, up from just 3,000 tonnes the previous year, and conducted biochar co-firing trials at a rate equivalent to 400,000 tonnes per annum to demonstrate the potential of CBC technology. It reduced CO 2 emissions in 2013/14 by more than 32,000 tonnes. 'Legislation and regulations define biomass as renewable,' said Delta Electricity sustainability manager Justin Flood. 'By preferring biomass over coal, the carbon in the coal is not burnt and remains locked up.' One biomass source is wood waste that would normally go to landfill, but the primary driver of Delta's recent increase in co-firing is sawmill residues. 'Previously there was a higher value market for the residues for paper pulp. However, when that market evaporated the timber industry was left with a sizable problem in terms of what to do with its residues and the loss of revenue,' said Flood. The way greenhouse gas accounting is conducted in Australia, with carbon emissions based on site activities, makes it difficult to undertake a life cycle assessment of the program. 'However, some of the international studies looking at this issue have concluded that the net carbon emissions of the biomass system are significantly lower than the coal system because of the uptake of carbon during biomass growth,' said Flood. Delta identified two challenges, sourcing the feedstock and that biomass conversion to electricity is slightly less

  20. The adhesion force of Notch with Delta and the rate of Notch signaling.

    Science.gov (United States)

    Ahimou, Francois; Mok, Lee-Peng; Bardot, Boris; Wesley, Cedric

    2004-12-20

    Notch signaling is repeatedly used during animal development to specify cell fates. Using atomic force microscopy on live cells, chemical inhibitors, and conventional analyses, we show that the rate of Notch signaling is linked to the adhesion force between cells expressing Notch receptors and Delta ligand. Both the Notch extracellular and intracellular domains are required for the high adhesion force with Delta. This high adhesion force is lost within minutes, primarily due to the action of Presenilin on Notch. Reduced turnover or Delta pulling accelerate this loss. These data suggest that strong adhesion between Notch and Delta might serve as a booster for initiating Notch signaling at a high rate.

  1. CCL20, (gamma)(delta) T cells, and IL-22 in corneal epithelial healing

    Science.gov (United States)

    After corneal epithelial abrasion, leukocytes and platelets rapidly enter the corneal stroma, and CCR6 (+) IL-17(+) gamma delta T cells migrate into the epithelium. Gamma delta T-cell-deficient (TCRd(-/-)) mice have significantly reduced inflammation and epithelial wound healing. Epithelial CCL20 mR...

  2. Multimode delta-E effect magnetic field sensors with adapted electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Zabel, Sebastian; Fichtner, Simon; Kirchhof, Christine; Quandt, Eckhard; Faupel, Franz, E-mail: ff@tf.uni-kiel.de [Faculty of Engineering, Institute for Materials Science, Kiel University, Kaiserstraße 2, 24143 Kiel (Germany); Reermann, Jens; Schmidt, Gerhard [Faculty of Engineering, Institute for Electrical Engineering, Kiel University, Kaiserstraße 2, 24143 Kiel (Germany); Wagner, Bernhard [Fraunhofer Institute for Silicon Technology ISIT, Fraunhoferstraße 1, 25524 Itzehoe (Germany)

    2016-05-30

    We present an analytical and experimental study on low-noise piezoelectric thin film resonators that utilize the delta-E effect of a magnetostrictive layer to measure magnetic fields at low frequencies. Calculations from a physical model of the electromechanical resonator enable electrode designs to efficiently operate in the first and second transversal bending modes. As predicted by our calculations, the adapted electrode design improves the sensitivity by a factor of 6 and reduces the dynamic range of the sensor output by 16 dB, which significantly eases the requirements on readout electronics. Magnetic measurements show a bandwidth of 100 Hz at a noise level of about 100 pTHz{sup −0.5}.

  3. Four new Delta Scuti stars

    Science.gov (United States)

    Schutt, R. L.

    1991-01-01

    Four new Delta Scuti stars are reported. Power, modified into amplitude, spectra, and light curves are used to determine periodicities. A complete frequency analysis is not performed due to the lack of a sufficient time base in the data. These new variables help verify the many predictions that Delta Scuti stars probably exist in prolific numbers as small amplitude variables. Two of these stars, HR 4344 and HD 107513, are possibly Am stars. If so, they are among the minority of variable stars which are also Am stars.

  4. Salinity Impacts on Agriculture and Groundwater in Delta Regions

    Science.gov (United States)

    Clarke, D.; Salehin, M.; Jairuddin, M.; Saleh, A. F. M.; Rahman, M. M.; Parks, K. E.; Haque, M. A.; Lázár, A. N.; Payo, A.

    2015-12-01

    Delta regions are attractive for high intensity agriculture due to the availability of rich sedimentary soils and of fresh water. Many of the world's tropical deltas support high population densities which are reliant on irrigated agriculture. However environmental changes such as sea level rise, tidal inundation and reduced river flows have reduced the quantity and quality of water available for successful agriculture. Additionally, anthropogenic influences such as the over abstraction of ground water and the increased use of low quality water from river inlets has resulted in the accumulation of salts in the soils which diminishes crop productivity. Communities based in these regions are usually reliant on the same water for drinking and cooking because surface water is frequently contaminated by commercial and urban pollution. The expansion of shallow tube well systems for drinking water and agricultural use over the last few decades has resulted in mobilisation of salinity in the coastal and estuarine fringes. Sustainable development in delta regions is becoming constrained by water salinity. However salinity is often studied as an independent issue by specialists working in the fields of agriculture, community water supply and groundwater. The lack of interaction between these disciplines often results in corrective actions being applied to one sector without fully assessing the effects of these actions on other sectors. This paper describes a framework for indentifying the causes and impacts of salinity in delta regions based on the source-pathway-receptor framework. It uses examples and scenarios from the Ganges-Brahmaputra-Meghna delta in Bangladesh together with field measurements and observations made in vulnerable coastal communities. The paper demonstrates the importance of creating an holistic understanding of the development and management of water resources to reduce the impact of salinity in fresh water in delta regions.

  5. Dynamic Balancing of Clavel’s Delta Robot

    NARCIS (Netherlands)

    van der Wijk, V.; Herder, Justus Laurens; Kecskemethy, Andres; Müller, Andreas

    2009-01-01

    The Delta robot has shown to be a useful device in many applications. Due to large accelerations however, vibrations can decrease the accuracy and performance considerably. Instead of common techniques to reduce vibrations such as damping or including waiting times in the motion cycle, this article

  6. Hydrological and Climatic Significance of Martian Deltas

    Science.gov (United States)

    Di Achille, G.; Vaz, D. A.

    2017-10-01

    We a) review the geomorphology, sedimentology, and mineralogy of the martian deltas record and b) present the results of a quantitative study of the hydrology and sedimentology of martian deltas using modified version of terrestrial model Sedflux.

  7. Adaptive delta management : Roots and branches

    NARCIS (Netherlands)

    Timmermans, J.S.; Haasnoot, M.; Hermans, L.M.; Kwakkel, J.H.; Rutten, M.M.; Thissen, W.A.H.

    2015-01-01

    Deltas are generally recognized as vulnerable to climate change and therefore a salient topic in adaptation science. Deltas are also highly dynamic systems viewed from physical (erosion, sedimentation, subsidence), social (demographic), economic (trade), infrastructures (transport, energy,

  8. Adaptive Delta Management : Roots and Branches

    NARCIS (Netherlands)

    Timmermans, Jos; Haasnoot, Marjolijn; Hermans, Leon; Kwakkel, Jan H.; Rutten, Maarten; Thissen, Wil A.H.; Mynett, Arthur

    2015-01-01

    Deltas are generally recognized as vulnerable to climate change and therefore a salient topic in adaptation science. Deltas are also highly dynamic systems viewed from physical (erosion, sedimentation, subsidence), social (demographic), economic (trade), infrastructures (transport, energy,

  9. Delta Vegetation and Land Use [ds292

    Data.gov (United States)

    California Natural Resource Agency — Vegetation and land use are mapped for the approximately 725,000 acres constituting the Legal Delta portion of the Sacramento and San Joaquin River Delta area....

  10. Delta Scuti variables. Lecture 6

    International Nuclear Information System (INIS)

    Cox, A.N.

    1983-01-01

    The class of variables near or on the upper main sequence, the delta Scuti variables, are not only the usual ones about the masses, radii, and luminosities, but also the age, rotation, element diffusion to change the surface layer composition, the occurance of convection and the presence of radial and nonradial pulsation modes

  11. about the Dirac Delta Function(?)

    Indian Academy of Sciences (India)

    V Balakrishnan is in the. Department of ... and sweet as befits this impatient age. It said (in its en- ... to get down to real work by shutting down the system and reverting to ... the Dirac delta function" - but do note the all-important question mark in ...

  12. THE RURAL TOURISM IN DANUBE DELTA

    Directory of Open Access Journals (Sweden)

    Ionica SOARE

    2014-06-01

    Full Text Available Purpose - the purpose of this paper is to evaluate the rural areas has market size and forecast its development as an economic activity. The present paper aims at analyzing the rural areas has in Danube Delta. In an enviable BAs which have responsibility for their particular isolated, such as the Danube Delta and the Danube that used, fishing and rural areas has the main activities that provide jobs and income sources for local populations. Design/methodology/approach - A survey was administered to customers’ rural hostel accommodation in Danube Delta. Descriptive statistics method was mainly adopted to calculate the mean with standard deviation of entry assumes variable, and to examine the different levels of consumers' awareness. The index values of product familiarity, the ratio between entries assumes product's familiarity value and the average value. Findings - the research results show hash has rural consumers have different perception and accomplished through behaviour. The information channels of brand hash mainly from friends, relatives and neighbours, so word of mouth spreading is very important for a brand. Women show a higher sensitivity in health and are currently operating the propensity than referred to follow the recommendations for nutrition. Research limitations/implications - This item is intended to synthesize developments and challenges," on June 13th rural market growth has. The results of this paper should be considered tentatively until has also features replicated by larger has rural consumers. Originality/value - members of rural areas has consumer's behavior would improve marketing and the development of rural areas has products, in order to reduce consumer confusion.

  13. Flipped SU(5) predicts {delta}T/T

    Energy Technology Data Exchange (ETDEWEB)

    Kyae, Bumseok [School of Physics, Korea Institute for Advanced Study, 207-43, Cheongnyangni-Dong, Dongdaemun-Gu, Seoul 130-722 (Korea, Republic of)]. E-mail: bkyae@kias.re.kr; Shafi, Qaisar [Bartol Research Institute, Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States)]. E-mail: shafi@bartol.udel.edu

    2006-04-20

    We discuss hybrid inflation in supersymmetric flipped SU(5) model such that the cosmic microwave anisotropy {delta}T/T is essentially proportional to (M/M{sub P}){sup 2}, where M denotes the symmetry breaking scale and M{sub P} (=2.4x10{sup 18} GeV) is the reduced Planck mass. The magnitude of M determined from {delta}T/T measurements can be consistent with the value inferred from the evolution of SU(3) and SU(2) gauge couplings. In other words, one could state that flipped SU(5) predicts (more precisely 'postdicts') {delta}T/T. The scalar spectral index n{sub s}=0.993+/-0.007, the scalar to tensor ratio satisfies r-bar 10{sup -6}, while dn{sub s}/dlnk-bar 4x10{sup -4}.

  14. Variation in leaf water delta D and delta 18O values during the evapotranspiration process

    International Nuclear Information System (INIS)

    Leopoldo, P.R.; Foloni, L.L.

    1984-01-01

    A theoretical model was developed to evaluate leaf water delta D and delta 18 O variation in relation to: leaf temperature, relative humidity converted to leaf temperature and delta D and delta 18 O values of atmospheric water vapour and soil water. (M.A.C.) [pt

  15. An analytical framework for strategic delta planning

    NARCIS (Netherlands)

    Seijger, C.; Douven, W.; Halsema, van G.; Hermans, L.; Evers, J.; Phi, H.L.; Khan, M.F.; Brunner, J.; Pols, L.; Ligtvoet, W.; Koole, S.; Slager, K.; Vermoolen, M.S.; Hasan, S.; Thi Minh Hoang, Vo

    2017-01-01

    Sectoral planning on water, agriculture and urban development has not been able to prevent increased flood risks and environmental degradation in many deltas. Governments conceive strategic delta planning as a promising planning approach and develop strategic delta plans. Such plans are linked to

  16. Delta Semantics Defined By Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt; Kyng, Morten; Madsen, Ole Lehrmann

    and the possibility of using predicates to specify state changes. In this paper a formal semantics for Delta is defined and analysed using Petri nets. Petri nets was chosen because the ideas behind Petri nets and Delta concide on several points. A number of proposals for changes in Delta, which resulted from...

  17. Astrometric Observation of Delta Cepheus

    Science.gov (United States)

    Warren, Naomi; Wilson, Betsie; Estrada, Chris; Crisafi, Kim; King, Jackie; Jones, Stephany; Salam, Akash; Warren, Glenn; Collins, S. Jananne; Genet, Russell

    2012-04-01

    Members of a Cuesta College astronomy research seminar used a manually-controlled 10-inch Newtonian Reflector telescope to determine the separation and position angle of the binary star Delta Cepheus. It was observed on the night of Saturday, October 29, 2011, at Star Hill in Santa Margarita, California. Their values of 40.2 arc seconds and 192.4 degrees were similar to those reported in the WDS (1910).

  18. delta-Opioid-induced pharmacologic myocardial hibernation during cardiopulmonary resuscitation.

    Science.gov (United States)

    Fang, Xiangshao; Tang, Wanchun; Sun, Shijie; Weil, Max Harry

    2006-12-01

    Cardiac arrest and cardiopulmonary resuscitation is an event of global myocardial ischemia and reperfusion, which is associated with severe postresuscitation myocardial dysfunction and fatal outcome. Evidence has demonstrated that mammalian hibernation is triggered by cyclic variation of a delta-opiate-like compound in endogenous serum, during which the myocardial metabolism is dramatically reduced and the myocardium tolerates the stress of ischemia and reperfusion without overt ischemic and reperfusion injury. Previous investigations also proved that the delta-opioid agonist elicited the cardioprotection in a model of regional ischemic intact heart or myocyte. Accordingly, we were prompted to search for an alternative intervention of pharmacologically induced myocardial hibernation that would result in rapid reductions of myocardial metabolism and therefore minimize the myocardial ischemic and reperfusion injury during cardiac arrest and cardiopulmonary resuscitation. Prospective, controlled laboratory study. University-affiliated research laboratory. In the series of studies performed in the established rat and pig model of cardiac arrest and cardiopulmonary resuscitation, the delta-opioid receptor agonist, pentazocine, was administered during ventricular fibrillation. : The myocardial metabolism reflected by the concentration of lactate, or myocardial tissue PCO2 and PO2, is dramatically reduced during cardiac arrest and cardiopulmonary resuscitation. These are associated with less severe postresuscitation myocardial dysfunction and longer duration of postresuscitation survival. delta-Opioid-induced pharmacologic myocardial hibernation is an option to minimize the myocardial ischemia and reperfusion injury during cardiac arrest and cardiopulmonary resuscitation.

  19. Morphodynamic evolution of two deltas in arctic environments, east coast of Greenland

    DEFF Research Database (Denmark)

    Kroon, Aart; Pedersen, Jørn Bjarke Torp; Sigsgaard, Charlotte

    2011-01-01

    Changes in fluvial channel patterns on deltas have a significant impact on the coastal morphology along its fringes. Lateral channel migration can locally cause cliff erosion and introduce an extra sediment source in the local budget of an active delta plain. Stabilization of channels or even...... channel lobe switching reduce the fluvial impact on the delta and introduce the formation of beach ridges and spits along the (former) delta edge. These accumulative features are formed in the ice-free summer periods and fed by alongshore sediment input from adjacent shores due to wave-driven alongshore...... currents, and by the reworking of the sediments on the delta plain by wave-driven cross-shore processes....

  20. Deformation characteristics of {delta} phase in the delta-processed Inconel 718 alloy

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, H.Y., E-mail: haiyanzhang@imr.ac.cn [Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Zhang, S.H., E-mail: shzhang@imr.ac.cn [Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Cheng, M. [Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016 (China); Li, Z.X. [Beijing Institute of Aeronautica1 Materials, Beijing 100095 (China)

    2010-01-15

    The hot working characteristics of {delta} phase in the delta-processed Inconel 718 alloy during isothermal compression deformation at temperature of 950 deg. C and strain rate of 0.005 s{sup -1}, were studied by using optical microscope, scanning electron microscope and quantitative X-ray diffraction technique. The results showed that the dissolution of plate-like {delta} phase and the precipitation of spherical {delta} phase particles coexisted during the deformation, and the content of {delta} phase decreased from 7.05 wt.% to 5.14 wt.%. As a result of deformation breakage and dissolution breakage, the plate-like {delta} phase was spheroidized and transferred to spherical {delta} phase particles. In the center with largest strain, the plate-like {delta} phase disappeared and spherical {delta} phase appeared in the interior of grains and grain boundaries.

  1. Migration in Deltas: An Integrated Analysis

    Science.gov (United States)

    Nicholls, Robert J.; Hutton, Craig W.; Lazar, Attila; Adger, W. Neil; Allan, Andrew; Arto, Inaki; Vincent, Katharine; Rahman, Munsur; Salehin, Mashfiqus; Sugata, Hazra; Ghosh, Tuhin; Codjoe, Sam; Appeaning-Addo, Kwasi

    2017-04-01

    Deltas and low-lying coastal regions have long been perceived as vulnerable to global sea-level rise, with the potential for mass displacement of exposed populations. The assumption of mass displacement of populations in deltas requires a comprehensive reassessment in the light of present and future migration in deltas, including the potential role of adaptation to influence these decisions. At present, deltas are subject to multiple drivers of environmental change and often have high population densities as they are accessible and productive ecosystems. Climate change, catchment management, subsidence and land cover change drive environmental change across all deltas. Populations in deltas are also highly mobile, with significant urbanization trends and the growth of large cities and mega-cities within or adjacent to deltas across Asia and Africa. Such migration is driven primarily by economic opportunity, yet environmental change in general, and climate change in particular, are likely to play an increasing direct and indirect role in future migration trends. The policy challenges centre on the role of migration within regional adaptation strategies to climate change; the protection of vulnerable populations; and the future of urban settlements within deltas. This paper reviews current knowledge on migration and adaptation to environmental change to discern specific issues pertinent to delta regions. It develops a new integrated methodology to assess present and future migration in deltas using the Volta delta in Ghana, Mahanadi delta in India and Ganges-Brahmaputra-Meghna delta across India and Bangladesh. The integrated method focuses on: biophysical changes and spatial distribution of vulnerability; demographic changes and migration decision-making using multiple methods and data; macro-economic trends and scenarios in the deltas; and the policies and governance structures that constrain and enable adaptation. The analysis is facilitated by a range of

  2. Economic Costs and Adaptations for Alternative Regulations of California's Sacramento–San Joaquin Delta

    Directory of Open Access Journals (Sweden)

    Stacy K. Tanaka

    2011-07-01

    Full Text Available Stacy K. Tanaka, Christina R. Connell–Buck, Kaveh Madani, Josue Medellín-Azuara, Jay R. Lund, and Ellen Hanakdoi: http://dx.doi.org/10.15447/sfews.2014v9iss2art4Water exports from California’s Sacramento–San Joaquin Delta are an environmental concern because they reduce net outflows of fresh water from the Delta, and can entrain fish and disrupt flows within the Delta. If exports were no longer pumped from within the Delta, the regulatory issue becomes one of maintaining appropriate flows into and out of the Delta. This paper presents the results of two sets of hydro-economic optimization modeling runs, which were developed to represent a range of modified Delta operations and their economic and operational effects on California’s water supply system. The first set of runs represents decreasing export capacity from the Delta. The second set increases minimum net Delta outflow (MNDO requirements. The hydro-economic model seeks the least–cost statewide water management scheme for water supply, including a wide range of resources and water management options. Results show that reducing exports or increasing MNDO requirements increase annual average statewide water scarcity, scarcity costs, and operating costs (from greater use of desalination, wastewater recycling, water treatment, and pumping. Effects of reduced exports are especially concentrated in agricultural communities in the southern Central Valley because of their loss of access to overall water supply exports and their ability to transfer remaining water to southern California. Increased outflow requirements increase water scarcity and associated costs throughout California. For an equivalent amount of average Delta outflows, statewide costs increase more rapidly when exports alone are reduced than when minimum outflow requirements are increased and effects are more widely distributed statewide.

  3. Carbon storage in the Mississippi River delta enhanced by environmental engineering

    Science.gov (United States)

    Shields, Michael R.; Bianchi, Thomas S.; Mohrig, David; Hutchings, Jack A.; Kenney, William F.; Kolker, Alexander S.; Curtis, Jason H.

    2017-11-01

    River deltas have contributed to atmospheric carbon regulation throughout Earth history, but functioning in the modern era has been impaired by reduced sediment loads, altered hydrologic regimes, increased global sea-level rise and accelerated subsidence. Delta restoration involves environmental engineering via river diversions, which utilize self-organizing processes to create prograding deltas. Here we analyse sediment cores from Wax Lake delta, a product of environmental engineering, to quantify the burial of organic carbon. We find that, despite relatively low concentrations of organic carbon measured in the cores (about 0.4%), the accumulation of about 3 T m-2 of sediment over the approximate 60 years of delta building resulted in the burial of a significant amount of organic carbon (16 kg m-2). This equates to an apparent organic carbon accumulation rate of 250 +/- 23 g m-2 yr-1, which implicitly includes losses by carbon emissions and erosion. Our estimated accumulation rate for Wax Lake delta is substantially greater than previous estimates based on the top metre of delta sediments and comparable to those of coastal mangrove and marsh habitats. The sedimentation of carbon at the Wax Lake delta demonstrates the capacity of engineered river diversions to enhance both coastal accretion and carbon burial.

  4. Future Deltas Utrecht University research focus area: towards sustainable management of sinking deltas

    Science.gov (United States)

    Stouthamer, E.; van Asselen, S.

    2015-11-01

    Deltas are increasingly under pressure from human impact and climate change. To deal with these pressures that threat future delta functioning, we need to understand interactions between physical, biological, chemical and social processes in deltas. This requires an integrated approach, in which knowledge on natural system functioning is combined with knowledge on spatial planning, land and water governance and legislative frameworks. In the research focus area Future Deltas of Utrecht University an interdisciplinary team from different research groups therefore works together. This allows developing integrated sustainable and resilient delta management strategies, which is urgently needed to prevent loss of vital delta services.

  5. El plan del delta - Holanda

    Directory of Open Access Journals (Sweden)

    Editorial, Equipo

    1963-09-01

    Full Text Available Holland is very poor in land resources. Hence its development has been directed towards intensive industrialization and maximum agricultural exploitation. The western part of the country is below sea level and is occupied by 65 percent of the population. Originally the coast consisted of a number of islands, estuaries and slight elevations. Man has transformed this coastline, first making a number of artificial lakes, or polders, and then converting these into fertile districts. These projects protect the soil by means of dykes, which require careful conservation, but even so violent floods are not infrequent. One of the difficult problems involved in this vast enterprise is the complex system of water supply, lines of communication and flow of the rivers into the sea along the estuary zone. This zone is on the south west, and to protect it a National Commission has been set up. After careful study, it was decided that the best defense against the violence of the sea would consist in closing off the inroads of the sea into the continental coastline. The set of hydraulic projects which constitutes this plan for the improvement of the sea defences will take 25 years to fulfil. The general project is highly ambitious and includes both maritime, road and structural works, in which there is a variety of stonework constructions. This paper describes, in brief outline, the main contents of the 11 headings into which the general construction project has been subdivided. In addition, this is supplemented with information on the projects which are already initiated and on the constructional procedure that is being adopted. Of these latter projects, the Nabla bridge is of particular interest. It is situated on the delta. It is made in prestressed concrete, and consists of 17 spans, of 60 length each. This enormous structure, in addition to its great length, and supporting a 22.8 ms wide roadway, is subjected to the tremendous forces 11» of the sea on one

  6. The Niger Delta Amnesty Program

    Directory of Open Access Journals (Sweden)

    Benjamin A. Okonofua

    2016-06-01

    Full Text Available The armed conflict between militias and government forces in Nigeria’s Niger Delta region has spanned for more than two decades, defying all solutions. A disarmament, demobilization, and reintegration (DDR program was established in August 2015 in effort to end the violence and has remained in place. It is a radically different approach from past approaches that displayed zero tolerance to all political challenges to oil production or the allocation of oil profits. The approach appeared to be immediately successful in that it forced a ceasefire, engaged militants in planned programs to rehabilitate and reintegrate them into civilian society, and opened up the oil wells (many of which had been shut due to the crisis with the effect of increasing government revenue, which depends 85% on oil exports. Yet, few studies have attempted to understand the dynamics within the country that are responsible for the design and implementation of this broad policy shift or to understand whether and how the current initiative is able to end the conflict and institute peace beyond the short term. This study, therefore, is important because it provides a critical perspective that anticipates and explains emerging issues with the Niger Delta Amnesty Program, which have implications for DDR adaptation and implementation all over the world. Ultimately, the research demonstrates how the DDR program both transforms the Niger Delta conflict and becomes embroiled in intense contestations not only about the mechanism for transforming the targeted population but also whether and how the program incorporates women who are being deprioritized by the program.

  7. Penelope Delta, recently discovered writer

    OpenAIRE

    MALAPANI A.

    2015-01-01

    The aim of this article is to present a Greek writer, Penelope Delta. This writer has recently come up in the field of the studies of the Greek literature and, although thereare neither many translations of her works in foreign languages nor many theses or dissertations, she was chosen for the great interest for her works. Her books have been read by many generations, so she is considered a classical writer of Modern Greek Literature. The way she uses the Greek language, the unique characters...

  8. From Natural to Design River Deltas

    Science.gov (United States)

    Giosan, Liviu

    2016-04-01

    Productive and biologically diverse, deltaic lowlands attracted humans since prehistory and may have spurred the emergence of the first urban civilizations. Deltas continued to be an important nexus for economic development across the world and are currently home for over half a billion people. But recently, under the double whammy of sea level rise and inland sediment capture behind dams, they have become the most threatened coastal landscape. Here I will address several deceptively simple questions to sketch some unexpected answers using example deltas from across the world from the Arctic to the Tropics, from the Danube to the Indus, Mississippi to Godavari and Krishna, Mackenzie to Yukon. What is a river delta? What is natural and what is not in a river delta? Are the geological and human histories of a delta important for its current management? Is maintaining a delta the same to building a new one? Can we design better deltas than Nature? These answers help us see clearly that survival of deltas in the next century depends on human intervention and is neither assured nor simple to address or universally applicable. Empirical observations on the hydrology, geology, biology and biochemistry of deltas are significantly lagging behind modeling capabilities endangering the applicability of numerical-based reconstruction solutions and need to be ramped up significantly and rapidly across the world.

  9. Identification of di- and tri-substituted hydroxy and ketone metabolites of delta1-tetrahydrocannabinol in mouse liver.

    Science.gov (United States)

    Harvey, D J; Martin, B R; Paton, W D

    1977-08-01

    In vivo liver metabolites of delta1-tetrahydrocannabinol (delta1-THC) were examined with a gas chromatograph--mass spectrometer--computer system as trimethylsilyl (TMS), [2H9]TMS and methyloxime-TMS derivatives. In addition to the reported monohydroxy, acid, and hydroxyacid metabolites, the following multiply substituted metabolites were identified: 2'',7-, 3'', 7-, and 6beta,7-dihydroxy-delta1-THC; 2'',6alpha,7-, and 3'',6alpha,7-trihydroxy-delta1-THC; 2''-, 3''-, and 7-hydroxy-6-oxo-delta1-THC, and 2'',7- and 3'',7-dihydroxy-6-oxo-delta1-THC. The ketones and hydroxyacids were reduced to common alcohols with lithium aluminium deuteride and the number of deuterium atoms in the product was used to distinguish the metabolic alcohols from those produced by reduction.

  10. Cohesive Sedimentary Processes on River-Dominated Deltas: New Perspectives from the Mississippi River Delta Front, Gulf of Mexico

    Science.gov (United States)

    Bentley, S. J.; Keller, G. P.; Obelcz, J.; Maloney, J. M.; Xu, K.; Georgiou, I. Y.; Miner, M. D.

    2016-12-01

    On river deltas dominated by proximal sediment accumulation (Mississippi, Huang He, others), the delta front region is commonly dominated by rapid accumulation of cohesive fluvial sediments, and mass-wasting processes that remobilize recently deposited sediments. Mass transport is preconditioned in sediments by high water content, biogenic gas production, over steepening, and is commonly triggered by strong wave loading and other processes. This understanding is based on extensive field studies in the 1970's and 80's. Recent studies of the Mississippi River Delta Front are yielding new perspectives on these processes, in a time of anthropogenically reduced sediment loads, rising sea level, and catastrophic deltaic land loss. We have synthesized many industry data sets collected since ca. 1980, and conducted new pilot field and modeling studies of sedimentary and morphodynamic processes. These efforts have yielded several key findings that diverge from historical understanding of this dynamic setting. First, delta distributary mouths have ceased seaward progradation, ending patterns that have been documented since the 18th century. Second, despite reduced sediment supply, offshore mass transport continues, yielding vertical displacements at rates of 1 m/y. This displacement is apparently forced by wave loading from storm events of near-annual return period, rather than major hurricanes that have been the focus of most previous studies. Third, core analysis indicates that this vertical displacement is occurring along failure planes >3 m in the seabed, rather than in more recently deposited sediments closer to the sediment-water interface. These seabed morphodynamics have the potential to destabilize both nearshore navigation infrastructure, and seabed hydrocarbon infrastructure offshore. As well, these findings raise more questions regarding the future seabed evolution offshore of major river deltas, in response to anthropogenic and climatic forcing.

  11. An analytical framework for strategic delta planning : negotiating consent for long-term sustainable delta development

    NARCIS (Netherlands)

    Seijger, C.; Douven, W; Hermans, L.M.; Evers, J.; Phi, H. L.; Brunner, J.; Pols, L.; Ligtvoet, W.; Koole, S.; Slager, K.; Vermoolen, M.S.; Hasan, S.; Hoang, V. T M; van Halsema, G

    2016-01-01

    Sectoral planning on water, agriculture and urban development has not been able to prevent increased flood risks and environmental degradation in many deltas. Governments conceive strategic delta planning as a promising planning approach and develop strategic delta plans. Such plans are linked to

  12. Entropy and optimality in river deltas

    Science.gov (United States)

    Tejedor, Alejandro; Longjas, Anthony; Edmonds, Douglas A.; Zaliapin, Ilya; Georgiou, Tryphon T.; Rinaldo, Andrea; Foufoula-Georgiou, Efi

    2017-10-01

    The form and function of river deltas is intricately linked to the evolving structure of their channel networks, which controls how effectively deltas are nourished with sediments and nutrients. Understanding the coevolution of deltaic channels and their flux organization is crucial for guiding maintenance strategies of these highly stressed systems from a range of anthropogenic activities. To date, however, a unified theory explaining how deltas self-organize to distribute water and sediment up to the shoreline remains elusive. Here, we provide evidence for an optimality principle underlying the self-organized partition of fluxes in delta channel networks. By introducing a suitable nonlocal entropy rate (nER) and by analyzing field and simulated deltas, we suggest that delta networks achieve configurations that maximize the diversity of water and sediment flux delivery to the shoreline. We thus suggest that prograding deltas attain dynamically accessible optima of flux distributions on their channel network topologies, thus effectively decoupling evolutionary time scales of geomorphology and hydrology. When interpreted in terms of delta resilience, high nER configurations reflect an increased ability to withstand perturbations. However, the distributive mechanism responsible for both diversifying flux delivery to the shoreline and dampening possible perturbations might lead to catastrophic events when those perturbations exceed certain intensity thresholds.

  13. A Modal Logic for Abstract Delta Modeling

    NARCIS (Netherlands)

    F.S. de Boer (Frank); M. Helvensteijn (Michiel); J. Winter (Joost)

    2012-01-01

    htmlabstractAbstract Delta Modeling is a technique for implementing (software) product lines. Deltas are put in a partial order which restricts their application and are then sequentially applied to a core product in order to form specific products in the product line. In this paper we explore the

  14. Tidal controls on river delta morphology

    NARCIS (Netherlands)

    Hoitink, A.J.F.; Wang, Z.B.; Vermeulen, B.; Huismans, Y.; Kästner, K.

    2017-01-01

    River delta degradation has been caused by extraction of natural resources, sediment retention by reservoirs, and sea-level rise. Despite global concerns about these issues, human activity in the world's largest deltas intensifies. Harbour development, construction of flood defences, sand mining and

  15. Tidal controls on river delta morphology

    NARCIS (Netherlands)

    Hoitink, A.J.F.; Wang, Zhengbing; Vermeulen, B.; Huismans, Y; Kästner, K

    River delta degradation has been caused by extraction of natural resources, sediment retention by reservoirs, and sea-level rise. Despite global concerns about these issues, human activity in the world’s largest deltas intensifies. Harbour development, construction of flood defences, sand mining and

  16. Floating City IJmeer : Accelerator for Delta Technology

    NARCIS (Netherlands)

    De Graaf, R.; Fremouw, M.; Van Bueren, B.; Czapiewska, K.; Kuijper, M.

    2006-01-01

    Climate change, sea level rise, population growth and ongoing urbanization result in higher vulnerability of the Rhine delta because it will result in increased flooding frequency, increasing investments and increased use of water, energy and other resources. The Rhine Delta also faces strong

  17. Entendiendo Delta desde las Humanidades

    Directory of Open Access Journals (Sweden)

    José Calvo Tello

    2016-05-01

    Full Text Available Stylometry is one of the research areas in greater development within Digital Humanities. However, few studies have worked until recently with texts in Spanish and even less so from Spanish-speaking countries. The aim of this paper is to present in Spanish, and without prior statistical knowledge from the reader, one of the main methods used in stylometry, the measure of textual distance Burrows’ Delta. This paper explains this measure using a very small corpus of proverbs and then checks the results in a corpus of Spanish novels. Both data and Python scripts are available to the community through GitHub, commented step by step so that you can play and visualize each step.

  18. EEHG at FLASH and DELTA

    Energy Technology Data Exchange (ETDEWEB)

    Molo, Robert; Hoener, Markus; Huck, Holger; Hacker, Kirsten; Khan, Shaukat; Schick, Andreas; Ungelenk, Peter; Zeinalzadeh, Maryam [Center for Synchrotron Radiation (DELTA), TU Dortmund University (Germany); Meulen, Peter van der; Salen, Peter [Stockholm University (Sweden); Angelova Hamberg, Gergana; Ziemann, Volker [Uppsala University (Sweden)

    2013-07-01

    The echo-enabled harmonic generation (EEHG) scheme utilizes two modulators with two magnetic chicanes in order to generate an electron density modulation with high harmonic content. In contrast to free-electron lasers (FEL) based on self-amplified spontaneous emission (SASE), the radiation of an EEHG FEL has better longitudinal coherence and is naturally synchronized with an external laser, which is advantageous for pump-probe applications. At the free-electron laser in Hamburg (FLASH), an EEHG experiment is currently under preparation. The short-pulse facility at DELTA (a 1.5-GeV synchrotron light source operated by the TU Dortmund University) based on coherent harmonic generation (CHG) will be upgraded using the EEHG technique in order to reach shorter wavelengths.

  19. River Delta Subsidence Measured with Interferometric Synthetic Aperture Radar (InSAR)

    Science.gov (United States)

    Higgins, Stephanie

    This thesis addresses the need for high-resolution subsidence maps of major world river deltas. Driven by a combination of rising water, sediment compaction, and reduced sediment supply due to damming and flood control, many deltas are sinking relative to sea level. A lack of data constraining rates and patterns of subsidence has made it difficult to determine the relative contributions of each factor in any given delta, however, or to assess whether the primary drivers of land subsidence are natural or anthropogenic. In recent years, Interferometric Synthetic Aperture Radar (InSAR) has emerged as a satellite-based technique that can map ground deformation with mm-scale accuracy over thousands of square kilometers. These maps could provide critical insight into the drivers of subsidence in deltas, but InSAR is not typically applied to non-urban delta areas due to the difficulties of performing the technique in wet, vegetated settings. This thesis addresses those difficulties and achieves high-resolution measurements of ground deformation in rural deltaic areas. Chapter 1 introduces the processes that drive relative sea level rise in river deltas and investigates open questions in delta subsidence research. Chapter 2 assesses the performance of InSAR in delta settings and reviews interferogram generation in the context of delta analysis, presenting delta-specific processing details and guiding interpretation in these challenging areas. Chapter 3 applies Differential (D-) InSAR to the coast of the Yellow River Delta in China. Results show that subsidence rates are as high as 250 mm/y due to groundwater extraction at aquaculture facilities, a rate that exceeds local and global average sea level rise by nearly two orders of magnitude and suggests a significant hazard for Asian megadeltas. Chapter 4 applies interferometric stacking and Small Baseline Subset (SBAS)-InSAR to the Ganges-Brahmaputra Delta, Bangladesh. Results show that stratigraphy controls subsidence in

  20. An automated technique for measuring deltaD and delta18O values of porewater by direct CO2 and H2 equilibration.

    Science.gov (United States)

    Koehler, G; Wassenaar, L I; Hendry, M J

    2000-11-15

    The stable-oxygen and -hydrogen isotopic values (deltaD, delta18O) of porewater in geologic media are commonly determined on water obtained by extraction techniques such as centrifugation, mechanical squeezing, vacuum heating and cryogenic microdistillation, and azeotropic distillation. Each of these techniques may cause isotopic fractionation as part the extraction process and each is laborious. Here we demonstrate a new approach to obtain automated, high-precision deltaD and delta18O measurements of porewater in geologic sediments by direct H2- and CO2-porewater equilibration using a modified commercial CO2-water equilibrator. This technique provides an important and cost-effective improvement over current extraction methods, because many samples can be rapidly analyzed with minimal handling, thereby reducing errors and potential for isotopic fractionation. The precision and accuracy of direct H2- and CO2-porewater equilibration is comparable to or better than current porewater extraction methods. Finally, the direct equilibration technique allows investigators to obtain high-resolution (cm scale) porewater deltaD and delta18O profiles using cores from individual boreholes, eliminating the need for costly piezometers or conventional porewater extractions.

  1. Growth laws for delta crevasses in the Mississippi River Delta: observations and modeling

    Science.gov (United States)

    Yocum, T. A.; Georgiou, I. Y.

    2016-02-01

    River deltas are accumulations of sedimentary deposits delivered by rivers via a network of distributary channels. Worldwide they are threatened by environmental changes, including subsidence, global sea level rise and a suite of other local factors. In the Mississippi River Delta (MRD) these impacts are exemplified, and have led to proposed solutions to build land that include sediment diversions, thereby reinitiating the delta cycle. While economically efficient, there are too few analogs of small deltas aside from laboratory studies, numerical modeling studies, theoretical approaches, and limited field driven observations. Anthropogenic crevasses in the modern delta are large enough to overcome limitations of laboratory deltas, and small enough to allow for "rapid" channel and wetland development, providing an ideal setting to investigate delta development mechanics. Crevasse metrics were obtained using a combination of geospatial tools, extracting key parameters (bifurcation length and width, channel order and depth) that were non-dimensionalized and compared to river-dominated delta networks previously studied. Analysis showed that most crevasses in the MRD appear to obey delta growth laws and delta allometry relationships, suggesting that crevasses do exhibit similar planform metrics to larger Deltas; the distance to mouth bar versus bifurcation order demonstrated to be a very reasonable first order estimate of delta-top footprint. However, some crevasses exhibited different growth metrics. To better understand the hydrodynamic and geomorphic controls governing crevasse evolution in the MRD, we assess delta dynamics via a suite of field observations and numerical modeling in both well-established and newly constructed crevasses. Our analysis suggests that delta development is affected by the relative influence of external (upstream and downstream) and internal controls on the hydrodynamic and sediment transport patterns in these systems.

  2. Influence of different organic fertilizers on quality parameters and the delta(15)N, delta(13)C, delta(2)H, delta(34)S, and delta(18)O values of orange fruit (Citrus sinensis L. Osbeck).

    Science.gov (United States)

    Rapisarda, Paolo; Camin, Federica; Fabroni, Simona; Perini, Matteo; Torrisi, Biagio; Intrigliolo, Francesco

    2010-03-24

    To investigate the influence of different types of fertilizers on quality parameters, N-containing compounds, and the delta(15)N, delta(13)C, delta(2)H, delta (34)S, and delta(18)O values of citrus fruit, a study was performed on the orange fruit cv. 'Valencia late' (Citrus sinensis L. Osbeck), which was harvested in four plots (three organic and one conventional) located on the same farm. The results demonstrated that different types of organic fertilizers containing the same amount of nitrogen did not effect important changes in orange fruit quality parameters. The levels of total N and N-containing compounds such as synephrine in fruit juice were not statistically different among the different treatments. The delta(15)N values of orange fruit grown under fertilizer derived from animal origin as well as from vegetable compost were statistically higher than those grown with mineral fertilizer. Therefore, delta(15)N values can be used as an indicator of citrus fertilization management (organic or conventional), because even when applied organic fertilizers are of different origins, the natural abundance of (15)N in organic citrus fruit remains higher than in conventional ones. These treatments also did not effect differences in the delta(13)C, delta(2)H, delta(34)S, and delta(18)O values of fruit.

  3. Asymmetric Effects of Subaerial and Subaqueous Basement Slopes on Self-Similar Morphology of Prograding Deltas

    Science.gov (United States)

    Lai, Steven Yueh Jen; Hsiao, Yung-Tai; Wu, Fu-Chun

    2017-12-01

    Deltas form over basements of various slope configurations. While the morphodynamics of prograding deltas over single-slope basements have been studied previously, our understanding of delta progradation over segmented basements is still limited. Here we use experimental and analytical approaches to investigate the deltaic morphologies developing over two-slope basements with unequal subaerial and subaqueous slopes. For each case considered, the scaled profiles of the evolving delta collapse to a single profile for constant water and sediment influxes, allowing us to use the analytical self-similar profiles to investigate the individual effects of subaerial/subaqueous slopes. Individually varying the subaerial/subaqueous slopes exerts asymmetric effects on the morphologies. Increasing the subaerial slope advances the entire delta; increasing the subaqueous slope advances the upstream boundary of the topset yet causes the downstream boundary to retreat. The delta front exhibits a first-retreat-then-advance migrating trend with increasing subaqueous slope. A decrease in subaerial topset length is always accompanied by an increase in subaqueous volume fraction, no matter which segment is steepened. Applications are presented for estimating shoreline retreat caused by steepening of basement slopes, and estimating subaqueous volume and delta front using the observed topset length. The results may have implications for real-world delta systems subjected to upstream tectonic uplift and/or downstream subsidence. Both scenarios would exhibit reduced topset lengths, which are indicative of the accompanied increases in subaqueous volume and signal tectonic uplift and/or subsidence that are at play. We highlight herein the importance of geometric controls on partitioning of sediment between subaerial and subaqueous delta components.

  4. Stable Isotope (delta OXYGEN-18, Delta Deuterium, Delta CARBON-13) Dendroclimatological Studies in the Waterloo Region of Southern Ontario, Canada, Between AD 1610 and 1990.

    Science.gov (United States)

    Buhay, William Mark

    to constrain the paleoclimate interpretations from three species of trees that grew in different hydrologic settings. The inferred climate data, integrated with the hydrological setting of the trees and various climate modifying factors in the Great Lakes basin, generated an independent interpretation of summer and winter conditions in southwestern Ontario for the past 380 years. The inferred evidence indicates that conditions in southwestern Ontario between 1610 and 1750 typified those of "Little Ice Age" Europe by being cooler and drier than present. This probably resulted from a southerly positioning of the Polar Front, with respect to southwestern Ontario, which allowed sub-polar airmasses to dominantly influence this region. A subsequent retreat of the Polar Front north after 1750 allowed for a predominance of sub -tropical airmasses that resulted in warm-moist conditions and an increase in winter precipitation in this area between 1750 and 1850. Another advance of the Polar Front position south, sometime after 1850, renewed cool-dry conditions and reduced winter precipitation amounts in southwestern Ontario until the early twentieth century, after which time, climate ameliorated progressively. Typical of the findings in previous studies, a significant correlation between climate parameters and delta^{13}C_ {cellulose} values is observed for a tree (maple) from a groundwater recharge setting. The correlation is best between MAT and delta^ {13}C_{cellulose} values between 1610 and 1850. The breakdown of this correlation after 1850, due to enriched delta ^{13}C_{cellulose} values, could indicate that the tree is responding to an alteration in soil chemistry occurring due to the fallout of anthropogenically produced atmospheric pollutants. This is because the effects of depleted soil nutrients and/or leached phytotoxins on delta^ {13}C_{cellulose} values in wood cellulose, are similar to ones seen in trees that regularly experience drought stress.

  5. Tidal controls on river delta morphology

    Science.gov (United States)

    Hoitink, A. J. F.; Wang, Z. B.; Vermeulen, B.; Huismans, Y.; Kästner, K.

    2017-09-01

    River delta degradation has been caused by extraction of natural resources, sediment retention by reservoirs, and sea-level rise. Despite global concerns about these issues, human activity in the world’s largest deltas intensifies. Harbour development, construction of flood defences, sand mining and land reclamation emerge as key contemporary factors that exert an impact on delta morphology. Tides interacting with river discharge can play a crucial role in the morphodynamic development of deltas under pressure. Emerging insights into tidal controls on river delta morphology suggest that--despite the active morphodynamics in tidal channels and mouth bar regions--tidal motion acts to stabilize delta morphology at the landscape scale under the condition that sediment import during low flows largely balances sediment export during high flows. Distributary channels subject to tides show lower migration rates and are less easily flooded by the river because of opposing non-linear interactions between river discharge and the tide. These interactions lead to flow changes within channels, and a more uniform distribution of discharge across channels. Sediment depletion and rigorous human interventions in deltas, including storm surge defence works, disrupt the dynamic morphological equilibrium and can lead to erosion and severe scour at the channel bed, even decades after an intervention.

  6. Delta Electroproduction in 12-C

    Energy Technology Data Exchange (ETDEWEB)

    McLauchlan, Steven [Univ. of Glasgow, Scotland (United Kingdom)

    2003-01-01

    The Δ-nucleus potential is a crucial element in the understanding of the nuclear system. Previous electroexcitation measurements in the delta region reported a Q2 dependence of the Δ mass indicating that this potential is dependent on the momentum of the Δ. Such a dependence is not observed for protons and neutrons in the nuclear medium. This thesis presents the experimental study of the electroexcitation of the Δ resonance in 12C, performed using the high energy electron beam at the Thomas Jefferson National Accelerator Facility, and the near 4π acceptance detector CLAS that enables the detection of the full reaction final state. Inclusive, semi inclusive, and exclusive cross sections were measured with an incident electron beam energy of 1.162GeV over the Q2 range 0.175-0.475 (GeV/c)2. A Q2 dependence of the Δ mass was only observed in the exclusive measurements indicating that the Δ-nucleus potential is affected by the momentum of the Δ.

  7. Community-based restoration of desert wetlands: the case of the Colorado River delta

    Science.gov (United States)

    Osvel Hinojosa-Huerta; Mark Briggs; Yamilett Carrillo-Guerroro; Edward P. Glenn; Miriam Lara-Flores; Martha Roman-Rodriguez

    2005-01-01

    Wetland areas have been drastically reduced through the Pacific Flyway and the Sonoran Desert, with severe consequences for avian populations. In the Colorado River delta, wetlands have been reduced by 80 percent due to water management practices in the Colorado River basin. However, excess flows and agricultural drainage water has restored some areas, providing...

  8. Legal Delta Boundary, 2001, DWR [ds586

    Data.gov (United States)

    California Natural Resource Agency — The original topographic maps containing the drawn delta border were scanned from the Department of Water Resources. Images were registered to 1:24,000 USGS DRG's in...

  9. sheltered creeks in Niger Delta, Nigeria

    African Journals Online (AJOL)

    user

    2015-03-18

    Mar 18, 2015 ... 273 and 115,000 barrels, respectively, making the delta. *Corresponding author. .... content was transferred to savillex digestion bombs and concen- trated hydrochloric ... metals (Zn, Pb and Cu) by flame atomic absorption.

  10. South Local Government Area, Delta S

    African Journals Online (AJOL)

    ADOWIE PERE

    environs, Aniocha- South Local Government Area of Delta State, Nigeria was carried out with a view to determining the ... supply for physical industrial development to achieve maximum human .... the Schlumberger O' Neil software package.

  11. Delta-nucleus dynamics: proceedings of symposium

    Energy Technology Data Exchange (ETDEWEB)

    Lee, T.S.H.; Geesaman, D.F.; Schiffer, J.P. (eds.)

    1983-10-01

    The appreciation of the role in nuclear physics of the first excited state of the nucleon, the delta ..delta..(1232), has grown rapidly in the past decade. The delta resonance dominates nuclear reactions induced by intermediate energy pions, nucleons, and electromagnetic probes. It is also the most important non-nucleonic degree of freedom needed to resolve many fundamental problems encountered in the study of low-energy nuclear phenomena. Clearly, a new phase of nuclear physics has emerged and conventional thinking must be extended to account for this new dimension of nuclear dynamics. The most challenging problem we are facing is how a unified theory can be developed to describe ..delta..-nucleus dynamics at all energies. In exploring this new direction, it is important to have direct discussions among researchers with different viewpoints. Separate entries were prepared for the 49 papers presented. (WHK)

  12. Damped Oscillator with Delta-Kicked Frequency

    Science.gov (United States)

    Manko, O. V.

    1996-01-01

    Exact solutions of the Schrodinger equation for quantum damped oscillator subject to frequency delta-kick describing squeezed states are obtained. The cases of strong, intermediate, and weak damping are investigated.

  13. On the origin of delta spots

    International Nuclear Information System (INIS)

    Tang, F.

    1983-01-01

    Mount Wilson sunspot drawings from 1966 through 1980 were used in conjunction with Hα filtergrams from Big Bear Solar Observatory to examine the origin of delta spots, spots with bipolar umbrae within one penumbra. Of the six cases we studied, five were formed by the union of non-paired spots. They are either shoved into one another by two neighboring growing bipoles or by a new spot born piggy-back style on an existing spot of opposite polarity. Proper motions of the growing spots take on curvilinear paths around one another to avoid a collision. This is the shear motion observed in delta spots (Tanaka, 1979). In the remaining case, the delta spot was formed by spots that emerged as a pair. Our findings indicate no intrinsic differences in the formation or the behavior between delta spots of normal magnetic configuration. (orig.)

  14. 2016 Rose Ojowhoh Delta State Polytechnic, Ozoro

    African Journals Online (AJOL)

    OJOHWOH ROSE

    The study examined staff development and library services in academic libraries in Bayelsa and Delta States. ... academic libraries, whose responsibility will be to cater for the development of staff in all ramifications. ..... Human resource.

  15. AMNESTY IN THE NIGER DELTA: VERTICAL MOVEMENT ...

    African Journals Online (AJOL)

    OLAWUYI

    federal government, the Niger Delta communities claim that they are entitled to ... instability, macroeconomic challenges, inconsistent policy regimes to ..... continues they cannot threaten the stability of the country nor affect its continued.

  16. Astrobee Periodic Technical Review (PTR) Delta 3

    Science.gov (United States)

    Provencher, Christopher; Smith, Marion F.; Smith, Ernest Everett; Bualat, Maria Gabriele; Barlow, Jonathan Spencer

    2017-01-01

    Astrobee is a free flying robot for the inside of the International Space Station (ISS). The Periodic Technical Review (PTR) delta 3 is the final design review of the system presented to stakeholders.

  17. Migration in Vulnerable Deltas: A Research Strategy

    Science.gov (United States)

    Hutton, C.; Nicholls, R. J.; Allan, A.

    2015-12-01

    C. Hutton1, & R. J. Nicholls1, , 1 University of Southampton, University Road, Southampton, Hampshire, United Kingdom, SO17 1BJ. cwh@geodata. soton.ac.ukAbstractGlobally, deltas contain 500 million people and with rising sea levels often linked to large number of forced migrants are expected in the coming century. However, migration is already a major process in deltas, such as the growth of major cities such as Dhaka and Kolkata. Climate and environmental change interacts with a range of catchment and delta level drivers, which encompass a nexus of sea-level rise, storms, freshwater and sediment supply from the catchment, land degradation, subsidence, agricultural loss and socio-economic stresses. DECCMA (Deltas, Vulnerability and Climate Change: Migration and Adaptation/CARRIA) is investigating migration in the Ganges-Brahmaputra-Meghna (GBM), Mahanadi and Volta Deltas, including the influence of climate change. The research will explore migration from a range of perspectives including governance and stakeholder analysis, demographic analysis, household surveys of sending and receiving areas, macro-economic analysis, and hazards and hotspot analysis both historically and into the future. Migration under climate change will depend on other adaptation in the deltas and this will be examined. Collectively, integrated analysis will be developed to examine migration, other adaptation and development pathways with a particular focus on the implications for the poorest. This will require the development of input scenarios, including expert-derived exogenous scenarios (e.g., climate change) and endogenous scenarios of the delta developed in a participatory manner. This applied research will facilitate decision support methods for the development of deltas under climate change, with a focus on migration and other adaptation strategies.

  18. A novel mouse PKC{delta} splice variant, PKC{delta}IX, inhibits etoposide-induced apoptosis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jung D. [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Seo, Kwang W. [Department of Internal Medicines, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Lee, Eun A.; Quang, Nguyen N. [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Cho, Hong R. [Department of Surgery, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of); Kwon, Byungsuk, E-mail: bskwon@mail.ulsan.as.kr [School of Biological Sciences, University of Ulsan, Ulsan (Korea, Republic of); Biomedical Research Center, Ulsan University Hospital and School of Medicine, University of Ulsan, Ulsan (Korea, Republic of)

    2011-07-01

    Highlights: {yields} A novel PKC{delta} isoform, named PKC{delta}IX, that lacks the C1 domain and the ATP-binding site is ubiquitously expressed. {yields} PKC{delta}IX inhibits etoposide-induced apoptosis. {yields} PKC{delta}IX may function as an endogenous dominant negative isoform for PKC{delta}. -- Abstract: Protein kinase C (PKC) {delta} plays an important role in cellular proliferation and apoptosis. The catalytic fragment of PKC{delta} generated by caspase-dependent cleavage is essential for the initiation of etoposide-induced apoptosis. In this study, we identified a novel mouse PKC{delta} isoform named PKC{delta}IX (Genebank Accession No. (HQ840432)). PKC{delta}IX is generated by alternative splicing and is ubiquitously expressed, as seen in its full-length PKC{delta}. PKC{delta}IX lacks the C1 domain, the caspase 3 cleavage site, and the ATP binding site but preserves an almost intact c-terminal catalytic domain and a nuclear localization signal (NLS). The structural characteristics of PKC{delta}IX provided a possibility that this PKC{delta} isozyme functions as a novel dominant-negative form for PKC{delta} due to its lack of the ATP-binding domain that is required for the kinase activity of PKC{delta}. Indeed, overexpression of PKC{delta}IX significantly inhibited etoposide-induced apoptosis in NIH3T3 cells. In addition, an in vitro kinase assay showed that recombinant PKC{delta}IX protein could competitively inhibit the kinase activity of PKC{delta}. We conclude that PKC{delta}IX can function as a natural dominant-negative inhibitor of PKC{delta}in vivo.

  19. Modeling Anthropogenic Impact on Sediment Balance and Relative Sea-Level Rise in Contemporary and Future Deltas

    Science.gov (United States)

    Tessler, Z. D.; Vorosmarty, C. J.; Overeem, I.; Syvitski, J. P.

    2017-12-01

    Modern deltas are dependent on human-mediated freshwater and sediment fluxes. Changes to these fluxes impact delta biogeophysical functioning, and affect the long-term sustainability of these landscapes for both human and natural systems. Here we present contemporary estimates of long-term mean sediment balance and relative sea-level rise across 46 global deltas. We model ongoing development and scenarios of future water resource management and hydropower infrastructure in upstream river basins to explore how changing sediment fluxes impact relative sea-level in coastal delta systems. Model results show that contemporary sediment fluxes, anthropogenic drivers of land subsidence, and sea-level rise result in relative sea-level rise rates in deltas that average 6.8 mm/year. Currently planned or under-construction dams can be expected to increase rates of relative sea-level rise on the order of 1 mm/year. Some deltas systems, including the Magdalena, Orinoco, and Indus, are highly sensitive to future impoundment of river basins, with RSLR rates increasing up to 4 mm/year in a high-hydropower-utilization scenario. Sediment fluxes may be reduced by up to 60% in the Danube and 21% in the Ganges-Brahmaputra-Megnha if all currently planned dams are constructed. Reduced sediment retention on deltas due to increased river channelization and local flood controls increases RSLR on average by nearly 2 mm/year. Long-term delta sustainability requires a more complete understanding of how geophysical and anthropogenic change impact delta geomorphology. Strategies for sustainable delta management that focus on local and regional drivers of change, especially groundwater and hydrocarbon extraction and upstream dam construction, can be highly impactful even in the context of global climate-induced sea-level rise.

  20. A Novel Sigma-Delta Modulator with Fractional-Order Digital Loop Integrator

    Directory of Open Access Journals (Sweden)

    Chi Xu

    2017-01-01

    Full Text Available This paper proposes using a fractional-order digital loop integrator to improve the robust stability of Sigma-Delta modulator, thus extending the integer-order Sigma-Delta modulator to a non-integer-order (fractional-order one in the Sigma-Delta ADC design field. The proposed fractional-order Sigma-Delta modulator has reasonable noise characteristics, dynamic range, and bandwidth; moreover the signal-to-noise ratio (SNR is improved remarkably. In particular, a 2nd-order digital loop integrator and a digital PIλDμ controller are combined to work as the fractional-order digital loop integrator, which is realized using FPGA; this will reduce the ASIC analog circuit layout design and chip testing difficulties. The parameters of the proposed fractional-order Sigma-Delta modulator are tuned by using swarm intelligent algorithm, which offers opportunity to simplify the process of tuning parameters and further improve the noise performance. Simulation results are given and they demonstrate the efficiency of the proposed fractional-order Sigma-Delta modulator.

  1. Delta infection evidenced by radioimmunoanalysis in selected collectives

    Energy Technology Data Exchange (ETDEWEB)

    Kselikova, M; Horejsi, J; Urbankova, J

    1987-01-01

    The presence of the Delta agent within the population was tested by means of the Delta-antibody radioimmunoassay using competitive kits of the firms ABBOTT (ABBOTT-ANTI-DELTA) and SORIN (AB-DELTAK). The Delta-antibody was found in 3.2% HBV patients, 5% HBsAg carriers, and in 20.8% of specific anti-Hbs-immunoglobulin. In hemophiliacs and blood donors no Delta-antibody was seen.

  2. Delta infection evidenced by radioimmunoanalysis in selected collectives

    International Nuclear Information System (INIS)

    Kselikova, M.; Horejsi, J.; Urbankova, J.

    1987-01-01

    The presence of the Delta agent within the population was tested by means of the Delta-antibody radioimmunoassay using competitive kits of the firms ABBOTT (ABBOTT-ANTI-DELTA) and SORIN (AB-DELTAK). The Delta-antibody was found in 3.2% HBV patients, 5% HBsAg carriers, and in 20.8% of specific anti-Hbs-immunoglobulin. In hemophiliacs and blood donors no Delta-antibody was seen. (author)

  3. Houtman Abrolhos Isotope (delta 18O, delta 13C) Data for 1795 to 1994

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — DESCRIPTION: VARIABLES AND UNITS: Column #1: core depth in mm Column #2: delta C-13 vs V-PDB Column #3: delta O-18 vs V-PDB Column #4: assigned date in years A.D....

  4. The Enabling Delta Life Initiative - Global Programme of Action on Deltas - Programme description

    NARCIS (Netherlands)

    Driel, van W.F.; Skyllerstedt, S.; Wosten, J.H.M.

    2014-01-01

    Being ‘hotspots’ of human activity with generally high population densities, deltas are vulnerable to changes induced by a range of driving forces, both natural and anthropogenic. In addition to already existing challenges, uncertainty of the possible impacts of climate change, low lying deltas

  5. Analysis of a retrieved delta III total shoulder prosthesis.

    Science.gov (United States)

    Nyffeler, R W; Werner, C M L; Simmen, B R; Gerber, C

    2004-11-01

    A reversed Delta III total shoulder prosthesis was retrieved post-mortem, eight months after implantation. A significant notch was evident at the inferior pole of the scapular neck which extended beyond the inferior fixation screw. This bone loss was associated with a corresponding, erosive defect of the polyethylene cup. Histological examination revealed a chronic foreign-body reaction in the joint capsule. There were, however, no histological signs of loosening of the glenoid base plate and the stability of the prosthetic articulation was only slightly reduced by the eroded rim of the cup.

  6. Experiences with delta compression of data produced by DIII

    International Nuclear Information System (INIS)

    Henline, P.A.

    1986-01-01

    The amount of data collected for each tokamak experimental shot is rapidly increasing. This is caused by many factors, including more diagnostic experiments, reduced cost of electronics hardware (especially memory), and longer plasma duration. The design goal for the DIII-D tokamak is 25 Mbytes of data per shot. In order to store the shot data as one logical unit, the delta compression algorithm, as it was implemented at ORNL by E. Blair, is being used. Statistics on compression factors, times, and general usage will be presented for actual DIII data. Data for 8-, 10-, and 12-bit digitizers will be highlighted since this hardware is common to most sites

  7. Holocene evolution of a wave-dominated fan-delta: Godavari delta, India

    Science.gov (United States)

    Saito, Y.; Nageswara Rao, K.; Nagakumar, K.; Demudu, G.; Rajawat, A.; Kubo, S.; Li, Z.

    2013-12-01

    The Godavari delta is one of the world's largest wave-dominated deltas. The Godavari River arises in the Western Ghats near the west coast of India and drains an area of about 3.1x10^5 km^2, flowing about 1465 km southeast across the Indian peninsula to the Bay of Bengal. The Godavari delta consists of a gentle seaward slope from its apex (12 m elevation) at Rajahmundry and a coastal beach-ridge plain over a distance of about 75 km and covers ~5200 km^2 as a delta plain. The river splits into two major distributary channels, the Gautami and the Vasishta, at a barrage constructed in the mid-1800s. The coastal environment of the deltaic coast is microtidal (~1 m mean tidal range) and wave-dominated (~1.5 m mean wave height in the June-September SW monsoon season, ~0.8 m in the NE monsoon season). Models of the Holocene evolution of the Godavari delta have changed from a zonal progradation model (e.g. Nageswara Rao & Sadakata, 1993) to a truncated cuspate delta model (Nageswara Rao et al., 2005, 2012). Twelve borehole cores (340 m total length), taken in the coastal delta plain during 2010-2013, yielded more than 100 C-14 dates. Sediment facies and C-14 dates from these and previous cores and remote-sensing data support a new delta evolution model. The Holocene coastal delta plain is divided into two parts by a set of linear beach ridges 12-14 km landward from the present shoreline in the central part of the delta. The location of the main depocenter (lobe) has shifted during the Holocene from 1) the center to 2) the west, 3) east, 4) center, 5) west, and 6) east. The linear beach ridges separate the first three from the last three stages. These lobe shifts are controlled by river channel shifts near the apex. Just as the current linear shoreline of the central part of the delta and the concave-up nearshore topography are the result of coastal erosion of a cuspate delta, the linear beach ridges indicate a former eroded shoreline. An unconformity within the deltaic

  8. Open source integrated modeling environment Delta Shell

    Science.gov (United States)

    Donchyts, G.; Baart, F.; Jagers, B.; van Putten, H.

    2012-04-01

    In the last decade, integrated modelling has become a very popular topic in environmental modelling since it helps solving problems, which is difficult to model using a single model. However, managing complexity of integrated models and minimizing time required for their setup remains a challenging task. The integrated modelling environment Delta Shell simplifies this task. The software components of Delta Shell are easy to reuse separately from each other as well as a part of integrated environment that can run in a command-line or a graphical user interface mode. The most components of the Delta Shell are developed using C# programming language and include libraries used to define, save and visualize various scientific data structures as well as coupled model configurations. Here we present two examples showing how Delta Shell simplifies process of setting up integrated models from the end user and developer perspectives. The first example shows coupling of a rainfall-runoff, a river flow and a run-time control models. The second example shows how coastal morphological database integrates with the coastal morphological model (XBeach) and a custom nourishment designer. Delta Shell is also available as open-source software released under LGPL license and accessible via http://oss.deltares.nl.

  9. QCD in the {delta}-regime

    Energy Technology Data Exchange (ETDEWEB)

    Bietenholz, W. [Universidad Nacional Autonoma de Mexico, Mexico City (Mexico). Inst. de Ciencias Nucleares; Cundy, N. [Seoul National Univ. (Korea, Republic of). Lattice Gauge Theory Research Center; Goeckeler, M. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Horsley, R.; Zanotti, J.M. [Edinburgh Univ. (United Kingdom). School of Physics; Nakamura, Y. [Tsukuba Univ., Ibaraki (Japan). Center for Computational Sciences; Pleiter, D. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Rakow, P.E.L. [Liverpool Univ. (United Kingdom). Theoretical Physics Div.; Schierholz, G. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2011-03-15

    The {delta}-regime of QCD is characterised by light quarks in a small spatial box, but a large extent in (Euclidean) time. In this setting a specific variant of chiral perturbation theory - the {delta}-expansion - applies, based on a quantum mechanical treatment of the quasi onedimensional system. In particular, for vanishing quark masses one obtains a residual pion mass M{sup R}{sub {pi}}, which has been computed to the third order in the {delta}-expansion. A comparison with numerical measurements of this residual mass allows for a new determination of some Low Energy Constants, which appear in the chiral Lagrangian. We first review the attempts to simulate 2-flavour QCD directly in the {delta}-regime. This is very tedious, but results compatible with the predictions for M{sup R}{sub {pi}} have been obtained. Then we show that an extrapolation of pion masses measured in a larger volume towards the {delta}-regime leads to good agreement with the theoretical predictions. From those results, we also extract a value for the (controversial) sub-leading Low Energy Constant anti l{sub 3}. (orig.)

  10. The development of a laterally confined laboratory fan delta under sediment supply reduction

    Science.gov (United States)

    Zhang, Xiaofeng; Wang, Siqiang; Wu, Xi; Xu, Shun; Li, Zhangyong

    2016-03-01

    In previous fan delta experiments, the effect of lateral confinement was generally ignored as these fans were usually unconfined with semiconical geometries. However, in gorge areas, fan development is usually laterally confined by valley walls. This study investigates autogenic processes of fan deltas in a laterally confined experimental tank. The experiment is divided into three phases. The sediment supply is held constant within each phase, so the autogenic processes of the fan are separated from the allogenic forcings. Results indicate that laterally confined fan deltas have higher progradation and aggradation potential, more regular channel braiding, and more even transverse sedimentation than unconfined fans. Besides, responses of fan deltas to sediment supply reduction are investigated in this research. At the initiation of the second and third phases, sediment feed rates are instantaneously reduced so that the allogenic forcings are predominant. Observations show that under sediment supply reduction, channelization on fan deltas are more pronounced and durations of the fluvial cycles are longer. The adjustment of fan morphology becomes slower as the self-regulation capacity of the fan decreases with reduced sediment supply.

  11. A model of water and sediment balance as determinants of relative sea level rise in contemporary and future deltas

    Science.gov (United States)

    Tessler, Zachary D.; Vörösmarty, Charles J.; Overeem, Irina; Syvitski, James P. M.

    2018-03-01

    Modern deltas are dependent on human-mediated freshwater and sediment fluxes. Changes to these fluxes impact delta biogeophysical functioning and affect the long-term sustainability of these landscapes for human and for natural systems. Here we present contemporary estimates of long-term mean sediment balance and relative sea level rise across 46 global deltas. We model scenarios of contemporary and future water resource management schemes and hydropower infrastructure in upstream river basins to explore how changing sediment fluxes impact relative sea level rise in delta systems. Model results show that contemporary sediment fluxes, anthropogenic drivers of land subsidence, and sea level rise result in delta relative sea level rise rates that average 6.8 mm/y. Assessment of impacts of planned and under-construction dams on relative sea level rise rates suggests increases on the order of 1 mm/y in deltas with new upstream construction. Sediment fluxes are estimated to decrease by up to 60% in the Danube and 21% in the Ganges-Brahmaputra-Meghna if all currently planned dams are constructed. Reduced sediment retention on deltas caused by increased river channelization and management has a larger impact, increasing relative sea level rise on average by nearly 2 mm/y. Long-term delta sustainability requires a more complete understanding of how geophysical and anthropogenic change impact delta geomorphology. Local and regional strategies for sustainable delta management that focus on local and regional drivers of change, especially groundwater and hydrocarbon extraction and upstream dam construction, can be highly impactful even in the context of global climate-induced sea level rise.

  12. Large old trees influence patterns of delta13C and delta15N in forests.

    Science.gov (United States)

    Weber, Pascale; Bol, Roland; Dixon, Liz; Bardgett, Richard D

    2008-06-01

    Large old trees are the dominant primary producers of native pine forest, but their influence on spatial patterns of soil properties and potential feedback to tree regeneration in their neighbourhood is poorly understood. We measured stable isotopes of carbon (delta(13)C) and nitrogen (delta(15)N) in soil and litter taken from three zones of influence (inner, middle and outer zone) around the trunk of freestanding old Scots pine (Pinus sylvestris L.) trees, to determine the trees' influence on below-ground properties. We also measured delta(15)N and delta(13)C in wood cores extracted from the old trees and from regenerating trees growing within their three zones of influence. We found a significant and positive gradient in soil delta(15)N from the inner zone, nearest to the tree centre, to the outer zone beyond the tree crown. This was probably caused by the higher input of (15)N-depleted litter below the tree crown. In contrast, the soil delta(13)C did not change along the gradient of tree influence. Distance-related trends, although weak, were visible in the wood delta(15)N and delta(13)C of regenerating trees. Moreover, the wood delta(15)N of small trees showed a weak negative relationship with soil N content in the relevant zone of influence. Our results indicate that large old trees control below-ground conditions in their immediate surroundings, and that stable isotopes might act as markers for the spatial and temporal extent of these below-ground effects. John Wiley & Sons, Ltd

  13. Hepatitis delta genotypes in chronic delta infection in the northeast of Spain (Catalonia).

    Science.gov (United States)

    Cotrina, M; Buti, M; Jardi, R; Quer, J; Rodriguez, F; Pascual, C; Esteban, R; Guardia, J

    1998-06-01

    Based on genetic analysis of variants obtained around the world, three genotypes of the hepatitis delta virus have been defined. Hepatitis delta virus variants have been associated with different disease patterns and geographic distributions. To determine the prevalence of hepatitis delta virus genotypes in the northeast of Spain (Catalonia) and the correlation with transmission routes and clinical disease, we studied the nucleotide divergence of the consensus sequence of HDV RNA obtained from 33 patients with chronic delta hepatitis (24 were intravenous drug users and nine had no risk factors), and four patients with acute self-limited delta infection. Serum HDV RNA was amplified by the polymerase chain reaction technique and a fragment of 350 nucleotides (nt 910 to 1259) was directly sequenced. Genetic analysis of the nucleotide consensus sequence obtained showed a high degree of conservation among sequences (93% of mean). Comparison of these sequences with those derived from different geographic areas and pertaining to genotypes I, II and III, showed a mean sequence identity of 92% with genotype I, 73% with genotype II and 61% with genotype III. At the amino acid level (aa 115 to 214), the mean identity was 87% with genotype I, 63% with genotype II and 56% with genotype III. Conserved regions included the RNA editing domain, the carboxyl terminal 19 amino acids of the hepatitis delta antigen and the polyadenylation signal of the viral mRNA. Hepatitis delta virus isolates in the northeast of Spain are exclusively genotype I, independently of the transmission route and the type of infection. No hepatitis delta virus subgenotypes were found, suggesting that the origin of hepatitis delta virus infection in our geographical area is homogeneous.

  14. Abraham Reef Stable Isotope Data (delta 13C, delta 18O, delta 14C) for 1635-1957

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Site: Abraham Reef, 22ó 06'S, 153ó 00'E, Porites australiensus, Radiocarbon (delta 14C) and Stable Isotope (del 18O and del 13C) results from bi-annual samples from...

  15. Deltas on the move. Making deltas cope with the effects of climate change

    International Nuclear Information System (INIS)

    Reker, J.; Van Winden, A.; Braakhekke, W.; Vermaat, J.; Eleveld, M.; Janssen, R.; De Reus, N.; Omzigt, N.

    2006-01-01

    This scoping study is the first phase of a study aimed at: (a) providing knowledge on the potential of a system-based approach to deal with the effects of climate change as an alternative for the more traditional technical measures such as dams, dikes and surge barriers. This should be shown for both rich and poor countries and should address hydrological, ecological as well as socio-economic aspects; and (b) identifying the potential to market these results worldwide. To reach these objectives four research steps are defined: (1) to make an inventory of deltas: their vulnerability to the effects of climate change; (2) development of indicators for successful use of a system-based approach; (3) to provide an overview of the potential of soft measures for these deltas; (4) to select a number of deltas with potential for marketing system-based measures and the development of strategies to link economic and ecological objectives. This scoping study addresses step 1 only. The results from step 1 will be used as a starting point for steps 2 and 3. The outputs of this scoping study are threefold: a background report (this report); a flyer with a brief description of the findings; a website with information on delta's and how these may be affected by climate change. The scoping study will roughly outline which deltas are still functioning in a more or less natural manner - or could be (re)developed in that direction - and thus would be good candidates for a system-based approach. Chapter 2 gives a description of the geomorphological and ecological processes in a delta. In addition, those aspects of climate change that can have an effect on deltas are described. The third chapter deals with human interventions in deltas and whether or not they fit within a system-based approach. In a system-based approach, as presented in Chapter 4, natural processes are given free reign where possible. Chapter 5 shows how available data on deltas could be used in such a system

  16. Livelihood Capabilities and Pathways of Shrimp Farmers in the Mekong Delta, Vietnam

    NARCIS (Netherlands)

    Tran Thi Phung Ha, Ha; Dijk, van J.W.M.; Bosma, R.H.; Sinh, L.X.

    2013-01-01

    Shrimp farming is a major livelihood activity in the Mekong Delta in the southernmost part of Vietnam. The Vietnamese government has promoted shrimp farming as a way to reduce poverty, provide employment opportunities and increase exports to support economic development. The shrimp farming system,

  17. [Preparation and spectral analysis of a new type of blue light-emitting material delta-Alq3].

    Science.gov (United States)

    Wang, Hua; Hao, Yu-ying; Gao, Zhi-xiang; Zhou, He-feng; Xu, Bing-she

    2006-10-01

    In the present article, delta-Alq3, a new type of blue light-emitting material, was synthesized and investigated by IR spectra, XRD spectra, UV-Vis absorption spectra, photoluminescence (PL) spectra, and electroluminescence (EL) spectra. The relationship between molecular spatial structure and spectral characteristics was studied by the spectral analysis of delta-Alq3 and alpha-Alq3. Results show that a new phase of Alq3 (delta-Alq3) can be obtained by vacuum heating alpha-Alq3, and the molecular spatial structure of alpha-Alq3 changes during the vacuum heating. The molecular spatial structure of delta-Alq3 lacks symmetry compared to alpha-Alq3. This transformation can reduce the electron cloud density on phenoxide of Alq3 and weaken the intermolecular conjugated interaction between adjacent Alq3 molecules. Hence, the pi--pi* electron transition absorption peak of delta-Alq3 shifts toward short wavelength in UV-Vis absorption spectra, and the maximum emission peak of delta-Alq3 (lamda max = 480 nm) blue-shifts by 35 nm compared with that of alpha-Alq3 (lamda max = 515 nm) in PL spectra. The maximum emission peaks of delta-Alq3 and alpha-Alq3 are all at 520 nm in EL spectra.

  18. The Economic Dimensions of the Niger Delta Ethnic Conflicts (Pp ...

    African Journals Online (AJOL)

    User

    1970, the price of international oil stepped upwards following the Middle. Eastern Yom Kippur .... Over the years, the pleas of the Niger Delta people for accommodation are ignored or .... In a labour surplus region like the Niger Delta, budget.

  19. Conceptualizing delta forms and processes in Arctic coastal environments

    DEFF Research Database (Denmark)

    Bendixen, Mette; Kroon, Aart

    2017-01-01

    Climate warming in the Arctic directly causes two opposite changes in Arctic coastal systems: increased melt-water discharge through rivers induces extra influx of sediments and extended open water season increases wave impact which reworks and erodes the shores. A shoreline change analysis along...... and popped up as hotspots. The Tuapaat delta and Skansen delta showed large progradation rates (1.5 and 7m/yr) and migration of the adjacent barriers and spits. The dynamic behavior at the delta mouths was mainly caused by classic delta channel lobe switching at one delta (Tuapaat), and by a breach...... of the fringing spit at the other delta (Skansen). The longshore and cross-shore transports are responsible for reworking the sediment with a result of migrating delta mouths and adjacent subaqueous mouth bars. Seaward progradation of the deltas is limited due to the steep nature of the bathymetry in Disko Bay...

  20. Binding energies of two deltas bound states

    International Nuclear Information System (INIS)

    Sato, Hiroshi; Saito, Koichi.

    1982-06-01

    Bound states of the two-deltas system are investigated by employing the realistic one boson exchange potential. It is found that there exist many bound states in each isospin channel and also found that the tensor interaction plays important role in producing these bound states. Relationship between these bound states and dibaryon resonances is discussed. (J.P.N.)

  1. Solubility of hydrogen in delta iron

    International Nuclear Information System (INIS)

    Shapovalov, V.I.; Trofimenko, V.V.

    1979-01-01

    The solubility of hydrogen in iron (less than 0.002 % impurities) at temperatures of 800-1510 deg C and a pressure of 100 atm was measured. The heat of solution of hydrogen in delta-Fe, equal to 73 kJ/g-atom, is by far greater than the corresponding values for α- and γ-Fe

  2. Applications of Dirac's Delta Function in Statistics

    Science.gov (United States)

    Khuri, Andre

    2004-01-01

    The Dirac delta function has been used successfully in mathematical physics for many years. The purpose of this article is to bring attention to several useful applications of this function in mathematical statistics. Some of these applications include a unified representation of the distribution of a function (or functions) of one or several…

  3. Managing flood risks in the Mekong Delta

    NARCIS (Netherlands)

    Hoang, Long Phi; Biesbroek, Robbert; Tri, Van Pham Dang; Kummu, Matti; Vliet, van Michelle T.H.; Leemans, Rik; Kabat, Pavel; Ludwig, Fulco

    2018-01-01

    Climate change and accelerating socioeconomic developments increasingly challenge flood-risk management in the Vietnamese Mekong River Delta—a typical large, economically dynamic and highly vulnerable delta. This study identifies and addresses the emerging challenges for flood-risk management.

  4. Bioluminescent hydrocarbonclastic bacteria of the Niger Delta ...

    African Journals Online (AJOL)

    Utilization of three petroleum hydrocarbons (Mobil SAE 40 Engine Oil, Diesel and Bonny light Crude Oil) by four bioluminescent bacteria (Vibrio harveyi, V. fisheri, Photobacterium leiognathi and P. Phosphoreum isolated from the Bonny estuary in the Niger Delta, Nigeria was investigated. Microbial utilization was monitored ...

  5. The Delta Team: Empowering Adolescent Girls.

    Science.gov (United States)

    Hood, Marian White

    1994-01-01

    In response to adolescent girls' concerns about teen violence, rumors, grooming, careers, and equity, four women teachers and a woman administrator at a Maryland middle school developed the Delta Program. The program provides positive learning experiences, teaches social skills and conflict management techniques, empowers girls through mentoring…

  6. delta. -isobars and photodisintegration at intermediate energies

    Energy Technology Data Exchange (ETDEWEB)

    Suzumura, Jun-ichi; Futami, Yasuhiko [Science Univ. of Tokyo, Noda, Chiba (Japan). Faculty of Science and Technology

    1982-12-01

    The dynamics of the peak considered to be due to the two-nucleon process in the reaction /sup 9/Be(gamma, p) anything is investigated with the quasi-deuteron model. We show that the process is dominated by a two-nucleon mechanism with pion and rho-meson exchange through virtual delta-isobar formation (author).

  7. A Delta-V map of the known Main Belt Asteroids

    Science.gov (United States)

    Taylor, Anthony; McDowell, Jonathan C.; Elvis, Martin

    2018-05-01

    With the lowered costs of rocket technology and the commercialization of the space industry, asteroid mining is becoming both feasible and potentially profitable. Although the first targets for mining will be the most accessible near Earth objects (NEOs), the Main Belt contains 106 times more material by mass. The large scale expansion of this new asteroid mining industry is contingent on being able to rendezvous with Main Belt asteroids (MBAs), and so on the velocity change required of mining spacecraft (delta-v). This paper develops two different flight burn schemes, both starting from Low Earth Orbit (LEO) and ending with a successful MBA rendezvous. These methods are then applied to the ∼700,000 asteroids in the Minor Planet Center (MPC) database with well-determined orbits to find low delta-v mining targets among the MBAs. There are 3986 potential MBA targets with a delta-v < 8 km s-1 , but the distribution is steep and reduces to just 4 with delta-v < 7 km s-1. The two burn methods are compared and the orbital parameters of low delta-v MBAs are explored.

  8. Drowning of the Mississippi Delta due to insufficient sediment supply and global sea-level rise

    Science.gov (United States)

    Blum, Michael D.; Roberts, Harry H.

    2009-07-01

    Over the past few centuries, 25% of the deltaic wetlands associated with the Mississippi Delta have been lost to the ocean. Plans to protect and restore the coast call for diversions of the Mississippi River, and its associated sediment, to sustain and build new land. However, the sediment load of the Mississippi River has been reduced by 50% through dam construction in the Mississippi Basin, which could affect the effectiveness of diversion plans. Here we calculate the amount of sediment stored on the delta plain for the past 12,000 years, and find that mean storage rates necessary to construct the flood plain and delta over this period exceed modern Mississippi River sediment loads. We estimate that, in the absence of sediment input, an additional 10,000-13,500km2 will be submerged by the year 2100 owing to subsidence and sea-level rise. Sustaining existing delta surface area would require 18-24billiontons of sediment, which is significantly more than can be drawn from the Mississippi River in its current state. We conclude that significant drowning is inevitable, even if sediment loads are restored, because sea level is now rising at least three times faster than during delta-plain construction.

  9. Novel primary thymic defect with T lymphocytes expressing gamma delta T cell receptor

    DEFF Research Database (Denmark)

    Geisler, C; Pallesen, G; Platz, P

    1989-01-01

    Flow cytometric analysis of the peripheral blood mononuclear cells in a six year old girl with a primary cellular immune deficiency showed a normal fraction of CD3 positive T cells. Most (70%) of the CD3 positive cells, however, expressed the gamma delta and not the alpha beta T cell receptor....... Immunoprecipitation and sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) showed that most of the gamma delta T cell receptors existed as disulphide-linked heterodimers. Proliferative responses to mitogens were severely reduced, but specific antibody responses after vaccination could be detected...... deficiency associated with a high proportion of T cells expressing the gamma delta T cell receptor has been described in nude mice, and it is suggested that the immune deficiency of this patient may represent a human analogue....

  10. Three dimensional [delta]f simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. (Texas Univ., Austin, TX (United States). Inst. for Fusion Studies); Machida, S. (Superconducting Super Collider Lab., Dallas, TX (United States))

    1993-02-01

    A three dimensional [delta]f strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3-dimensional space charge effects and a [delta]f code. The [delta]f method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6-dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3-dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense where finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  11. Three dimensional {delta}f simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. [Texas Univ., Austin, TX (United States). Inst. for Fusion Studies; Machida, S. [Superconducting Super Collider Lab., Dallas, TX (United States)

    1993-02-01

    A three dimensional {delta}f strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3-dimensional space charge effects and a {delta}f code. The {delta}f method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6-dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3-dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense where finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  12. Three dimensional [delta][ital f] simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. (Institute for Fusion Studies, The University of Texas at Austin, Austin, Texas 78712-1060 (United States)); Machida, S. (SSC Laboratory, 2550 Beckleymeade Avenue, Dallas, Texas 75237 (United States))

    1993-12-25

    A three dimensional [delta][ital f] strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3 dimensional space charge effects and a [delta][ital f] code. The [delta][ital f] method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6 dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3 dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense with finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  13. Morphodynamics of a cyclic prograding delta: the Red River, Vietnam

    NARCIS (Netherlands)

    Maren, D.S. van

    2004-01-01

    River deltas are inhabited by over 60% of the world population, and are, consequently, of paramount agricultural and economical importance. They constitute unique wetland envi ronments which gives river deltas ecological importance as well. Additionally, many deltas contain large accumulations of

  14. Environmental challenges in Nigeria's Delta Region and Agriculture ...

    African Journals Online (AJOL)

    The paper discussed the environmental challenges in the Niger-Delta region of Nigeria with emphasis on the impacts on agricultural production. It thus discussed the concepts of Niger-Delta, Environmental pollution, Niger-Delta crises and Agriculture. The paper posits that there are positive relationships between these ...

  15. Evaluation of the Accuracy of NASS/CDS Delta-V Estimates from the Enhanced WinSmash Algorithm

    Science.gov (United States)

    Hampton, Carolyn E.; Gabler, Hampton C.

    2010-01-01

    The National Automotive Sampling System / Crashworthiness Data System (NASS/CDS) uses the WinSmash program to reconstruct changes in vehicle velocity for real world crashes. Vehicle change in velocity, or delta-V, is a measure of crash severity and a predictor of injury risk. Earlier studies have demonstrated that WinSmash 2.42 underestimated the delta-V by 23% on average with the use of categorical stiffness values for vehicles identified as a source of error. An enhanced version of WinSmash, WinSmash 2008, was developed to employ vehicle specific stiffness values whenever possible. A total of 478 General Motors vehicles equipped with event data recorders (EDRs) and involved in real-world crashes were collected from years 2000 – 2008 of the NASS/CDS database and the delta-V was computed using the enhanced WinSmash. All vehicles were involved in frontal impacts. The enhanced reconstruction algorithm reduced the underestimation of delta-V from 23% to 13% on average for all vehicles. Delta-V estimates for cars only were greatly improved but still understated by 16% on average. Less than 5% error in delta-V was observed for pickup trucks and utility vehicles. The amount of structural overlap for the vehicle and investigator confidence in the reconstruction continued to have an effect on accuracy. No difference in average delta-V was observed when using either updated categorical stiffness values or vehicle specific stiffness values. The changes in WinSmash delta-Vs have important policy implications for NHTSA as the NASS/CDS delta-Vs are the basis for traffic and safety regulations as well as the speeds for vehicular crash testing and costs/benefits analyses. PMID:21050607

  16. deltaPlotR: An R Package for Di?erential Item Functioning Analysis with Ango? s Delta Plot

    OpenAIRE

    David Magis; Bruno Facon

    2014-01-01

    Angoff's delta plot is a straightforward and not computationally intensive method to identify differential item functioning (DIF) among dichotomously scored items. This approach was recently improved by proposing an optimal threshold selection and by considering several item purification processes. Moreover, to support practical DIF analyses with the delta plot and these improvements, the R package deltaPlotR was also developed. The purpose of this paper is twofold: to outline the delta plot ...

  17. Erythromycin and azithromycin transport into Haemophilus influenzae ATCC 19418 under conditions of depressed proton motive force (delta mu H)

    Energy Technology Data Exchange (ETDEWEB)

    Capobianco, J.O.; Goldman, R.C. (Abbott Laboratories, IL (USA))

    1990-09-01

    The effect of collapsing the electrochemical proton gradient (delta mu H) on ({sup 3}H)erythromycin and ({sup 14}C)azithromycin transport in Haemophilus influenzae ATCC 19418 was studied. The proton gradient and membrane potential were determined from the distribution of (2-{sup 14}C)dimethadione and rubidium-86, respectively. delta mu H was reduced from 124 to 3 mV in EDTA-valinomycin-treated cells at 22{degrees}C with 150 mM KCl and 0.1 mM carbonyl cyanide m-chlorophenylhydrazone. During the collapse of delta mu H, macrolide uptake increased. Erythromycin efflux studies strongly suggested that this increase was not due to an energy-dependent efflux pump but was likely due to increased outer membrane permeability. These data indicated that macrolide entry was not a delta mu H-driven active transport process but rather a passive diffusion process.

  18. Sharing Remote and Local Information for Tracking Spring Breakup in the Mackenzie Delta and Beaufort Sea

    Science.gov (United States)

    Forbes, D. L.; Whalen, D.; Fraser, P.

    2015-12-01

    The Mackenzie Delta is the second largest on the Arctic Ocean, covering 13 000 km2. The annual flood regime in the delta is dominated by the spring snowmelt freshet and associated ice breakup, as water from the south arrives in the ice-covered delta and spreads over bottomfast and adjacent floating sea ice at the delta front. The complex processes of water-ice interaction, flow partitioning, and overbank flooding to replenish waters in 43 000 delta lakes threaten community, transportation, subsistence, and energy infrastructure in the delta. The annual breakup season is a time of rejuvenation, excitement, and anxiety for delta residents and stakeholders. To track the progress of breakup and meet the need for knowledge dissemination to the local communities, a Mackenzie-Beaufort breakup newsletter has been produced by Natural Resources Canada on a quasi-daily basis during the May-June spring flood season for 10 years, and distributed to an e-mail list that grew to over 300 subscribers. This provides near real-time tracking of water levels and breakup using on-line gauges (Environment Canada), daily MODIS satellite imagery (NASA), Landsat imagery (USGS) and intermittent radar imagery (various sources). In earlier years, information was also supplied from field programs operating in the delta during breakup, but changing priorities and funding have reduced the number of outside researchers present during these critical weeks. Meanwhile the number of local contributors has grown, providing observations and photographs to share with the local, regional and global readership. In this way the newsletter evolved into a two-way communication tool and community portal. The newsletter is a chronicle of each breakup season and a key resource for territorial and municipal managers, subsistence organizations, and emergency response agencies, with routine requests for specific imagery in areas of concern. With the completion of 10 years under the present model, we are exploring

  19. Turbidity and salinity affect feeding performance and physiological stress in the endangered delta smelt.

    Science.gov (United States)

    Hasenbein, Matthias; Komoroske, Lisa M; Connon, Richard E; Geist, Juergen; Fangue, Nann A

    2013-10-01

    Coastal estuaries are among the most heavily impacted ecosystems worldwide with many keystone fauna critically endangered. The delta smelt (Hypomesus transpacificus) is an endangered pelagic fish species endemic to the Sacramento-San Joaquin Estuary in northern California, and is considered as an indicator species for ecosystem health. This ecosystem is characterized by tidal and seasonal gradients in water parameters (e.g., salinity, temperature, and turbidity), but is also subject to altered water-flow regimes due to water extraction. In this study, we evaluated the effects of turbidity and salinity on feeding performance and the stress response of delta smelt because both of these parameters are influenced by water flows through the San Francisco Bay Delta (SFBD) and are known to be of critical importance to the completion of the delta smelt's life cycle. Juvenile delta smelt were exposed to a matrix of turbidities and salinities ranging from 5 to 250 nephelometric turbidity units (NTUs) and 0.2 to 15 parts per thousand (ppt), respectively, for 2 h. Best statistical models using Akaike's Information Criterion supported that increasing turbidities resulted in reduced feeding rates, especially at 250 NTU. In contrast, best explanatory models for gene transcription of sodium-potassium-ATPase (Na/K-ATPase)-an indicator of osmoregulatory stress, hypothalamic pro-opiomelanocortin-a precursor protein to adrenocorticotropic hormone (expressed in response to biological stress), and whole-body cortisol were affected by salinity alone. Only transcription of glutathione-S-transferase, a phase II detoxification enzyme that protects cells against reactive oxygen species, was affected by both salinity and turbidity. Taken together, these data suggest that turbidity is an important determinant of feeding, whereas salinity is an important abiotic factor influencing the cellular stress response in delta smelt. Our data support habitat association studies that have shown greater

  20. Investigation of the biodistribution, breakdown and excretion of delta inulin adjuvant.

    Science.gov (United States)

    Wang, Lixin; Barclay, Thomas; Song, Yunmei; Joyce, Paul; Sakala, Isaac G; Petrovsky, Nikolai; Garg, Sanjay

    2017-08-03

    Insoluble, nanostructured delta inulin particles enhance the immunogenicity of co-administered protein antigens and consequently are used as a vaccine adjuvant (Advax™). To better understand their immunomodulatory properties, the in vitro hydrolysis and in vivo distribution of delta inulin particles were investigated. Delta inulin particle hydrolysis under bio-relevant acidic conditions resulted in no observable change to the bulk morphology using SEM, and HPLC results showed that only 6.1% of the inulin was hydrolysed over 21days. However, 65% of the terminal glucose groups were released, showing that acid hydrolysis relatively rapidly releases surface bound chemistries. This was used to explain in vivo biodistribution results in which delta inulin particles surface-labelled with fluorescein-5-thiosemicabizide were administered to mice using intramuscular (I.M.) or subcutaneous (S.C.) routes. Comparison analysis of the fluorescence of soluble inulin in the supernatants of homogenised tissues maintained at room temperature or heated to 100°C to solubilise particulate inulin was used to distinguish between fluorescent probe on soluble inulin and probe bound to inulin within particles. Following both I.M. and S.C. injection delta inulin exhibited a depot behaviour with local injection site residence for several weeks. Over this time, as injection site inulin reduced, there was measurable transport of intact delta inulin particles by macrophages to secondary lymphoid organs and the liver. Ultimately, the injected delta inulin became solubilised resulting in its detection in the plasma and in the urine. Thus injected delta inulin particles are initially taken up by macrophages at the site of injection, trafficked to secondary lymphoid tissue and the liver, and hydrolysed resulting in their becoming soluble and diffusing into the blood stream, from whence they are glomerularly filtered and excreted into the urine. These results provide important insights into the

  1. Delta-nucleus dynamics: proceedings of symposium

    International Nuclear Information System (INIS)

    Lee, T.S.H.; Geesaman, D.F.; Schiffer, J.P.

    1983-10-01

    The appreciation of the role in nuclear physics of the first excited state of the nucleon, the delta Δ(1232), has grown rapidly in the past decade. The delta resonance dominates nuclear reactions induced by intermediate energy pions, nucleons, and electromagnetic probes. It is also the most important non-nucleonic degree of freedom needed to resolve many fundamental problems encountered in the study of low-energy nuclear phenomena. Clearly, a new phase of nuclear physics has emerged and conventional thinking must be extended to account for this new dimension of nuclear dynamics. The most challenging problem we are facing is how a unified theory can be developed to describe Δ-nucleus dynamics at all energies. In exploring this new direction, it is important to have direct discussions among researchers with different viewpoints. Separate entries were prepared for the 49 papers presented

  2. Inhibition of cortiocosteroidogenesis by delta-9-tetrahydrocannabinol.

    Science.gov (United States)

    Warner, W; Harris, L S; Carchman, R A

    1977-12-01

    ACTH, cholera toxin, cyclic AMP but not pregnenolone-induced steroidogenesis in Y-1 functional mouse adrenal tumor cells was significantly inhibited by delta-9-tetrahydrocannabinol, cannabidiol, and cannabinol. The inhibition of steroidogenesis could not be correlated with a general depression in cell function or viability. The data suggest that cannabinoids inhibit corticosteroidogenesis at a site between the synthesis of cAMP and of pregnenolone.

  3. Determination of the positions and residues of the. delta. /sup + +/ and. delta. /sup 0/ poles. [Phase shifts,coulomb corrections

    Energy Technology Data Exchange (ETDEWEB)

    Vasan, S S [Carnegie-Mellon Univ., Pittsburgh, Pa. (USA). Dept. of Physics

    1976-04-19

    The poles and the associated residues in the ..pi..N P/sub 33/ amplitude corresponding to the resonances ..delta../sup + +/ and ..delta../sup 0/ are determined by fitting the ..pi../sup +/p and ..pi../sup -/p hadronic phase shifts from the Carter 73 analysis. The ..delta../sup + +/ and ..delta../sup 0/ pole positions are determined also from the nuclear phase shifts, these being the phase shifts made up of the hadronic phase shifts plus the Coulomb corrections. The pole positions obtained from the two sets of phase shifts are different, the differences being larger in the case of the ..delta../sup + +/.

  4. Adaptive Delta Management: cultural aspects of dealing with uncertainty

    Science.gov (United States)

    Timmermans, Jos; Haasnoot, Marjolijn; Hermans, Leon; Kwakkel, Jan

    2016-04-01

    Deltas are generally recognized as vulnerable to climate change and therefore a salient topic in adaptation science. Deltas are also highly dynamic systems viewed from physical (erosion, sedimentation, subsidence), social (demographic), economic (trade), infrastructures (transport, energy, metropolization) and cultural (multi-ethnic) perspectives. This multi-faceted dynamic character of delta areas warrants the emergence of a branch of applied adaptation science, Adaptive Delta Management, which explicitly focuses on climate adaptation of such highly dynamic and deeply uncertain systems. The application of Adaptive Delta Management in the Dutch Delta Program and its active international dissemination by Dutch professionals results in the rapid dissemination of Adaptive Delta Management to deltas worldwide. This global dissemination raises concerns among professionals in delta management on its applicability in deltas with cultural conditions and historical developments quite different from those found in the Netherlands and the United Kingdom where the practices now labelled as Adaptive Delta Management first emerged. This research develops an approach and gives a first analysis of the interaction between the characteristics of different approaches in Adaptive Delta Management and their alignment with the cultural conditions encountered in various delta's globally. In this analysis, first different management theories underlying approaches to Adaptive Delta Management as encountered in both scientific and professional publications are identified and characterized on three dimensions: The characteristics dimensions used are: orientation on today, orientation on the future, and decision making (Timmermans, 2015). The different underlying management theories encountered are policy analysis, strategic management, transition management, and adaptive management. These four management theories underlying different approaches in Adaptive Delta Management are connected to

  5. Delta count-rate monitoring system

    International Nuclear Information System (INIS)

    Van Etten, D.; Olsen, W.A.

    1985-01-01

    A need for a more effective way to rapidly search for gamma-ray contamination over large areas led to the design and construction of a very sensitive gamma detection system. The delta count-rate monitoring system was installed in a four-wheel-drive van instrumented for environmental surveillance and accident response. The system consists of four main sections: (1) two scintillation detectors, (2) high-voltage power supply amplifier and single-channel analyzer, (3) delta count-rate monitor, and (4) count-rate meter and recorder. The van's 6.5-kW generator powers the standard nuclear instrument modular design system. The two detectors are mounted in the rear corners of the van and can be run singly or jointly. A solid-state bar-graph count-rate meter mounted on the dashboard can be read easily by both the driver and passenger. A solid-state strip chart recorder shows trends and provides a permanent record of the data. An audible alarm is sounded at the delta monitor and at the dashboard count-rate meter if a detected radiation level exceeds the set background level by a predetermined amount

  6. The sensitivity of the ESA DELTA model

    Science.gov (United States)

    Martin, C.; Walker, R.; Klinkrad, H.

    Long-term debris environment models play a vital role in furthering our understanding of the future debris environment, and in aiding the determination of a strategy to preserve the Earth orbital environment for future use. By their very nature these models have to make certain assumptions to enable informative future projections to be made. Examples of these assumptions include the projection of future traffic, including launch and explosion rates, and the methodology used to simulate break-up events. To ensure a sound basis for future projections, and consequently for assessing the effectiveness of various mitigation measures, it is essential that the sensitivity of these models to variations in key assumptions is examined. The DELTA (Debris Environment Long Term Analysis) model, developed by QinetiQ for the European Space Agency, allows the future projection of the debris environment throughout Earth orbit. Extensive analyses with this model have been performed under the auspices of the ESA Space Debris Mitigation Handbook and following the recent upgrade of the model to DELTA 3.0. This paper draws on these analyses to present the sensitivity of the DELTA model to changes in key model parameters and assumptions. Specifically the paper will address the variation in future traffic rates, including the deployment of satellite constellations, and the variation in the break-up model and criteria used to simulate future explosion and collision events.

  7. Understanding delta-sigma data converters

    CERN Document Server

    Pavan, Shanti; Temes, Gabor C

    2017-01-01

    This new edition introduces novel analysis and design techniques for delta-sigma (ΔΣ) converters in physical and conceptual terms, and includes new chapters that explore developments in the field over the last decade. This book explains the principles and operation of delta-sigma analog-to-digital converters (ADCs) in physical and conceptual terms in accordance with the most recent developments in the field. The interest of ΔΣ converter designers has shifted significantly over the past decade, due to many new applications for data converters at the far ends of the frequency spectrum. Continuous-time delta-sigma A/D converters with GHz clocks, of both lowpass and bandpass types, are required for wireless applications. At the other extreme, multiplexed ADCs with very narrow (sometimes 10 Hz wide) signal bandwidths, but very high accuracy are needed in the interfaces of biomedical and environmental sensors. To reflect the changing eeds of designers, the second edition includes significant new material on bo...

  8. Real And Reactive Power Saving In Three Phase Induction Machine Using Star-Delta Switching Schemes

    Directory of Open Access Journals (Sweden)

    Ramesh Daravath

    2017-04-01

    Full Text Available Induction machines are the most commonly used industrial drives for variety of applications. It has been estimated that induction motors consumes approximately 50 of all the electric energy generated. Further in the area of renewable energy sources such as wind or bio-mass energy induction machines have been found suitable for functioning as generators. In this context it may be mentioned that a star-delta switching is common for the starting of three-phase induction motor. Now it is proposed to use this star-delta switching for energy conservation of induction machines i.e. at times of reduced loads the machine switched back to star connection. Using a three-phase 400 V 50 Hz 4-pole induction machine it has been demonstrated that the star-delta switching of stator winding of three-phase induction machine motor generator operations reconnected in star at suitable reduced loads with a switching arrangement can result in improved efficiency and power factor as compared to a fixed delta or star connection. The predetermined values along with the experimental results have also been presented in this report. A simulation program has been developed for the predetermination of performance of the three-phase induction machine using exact equivalent circuit. A case study on a 250 kW 400 V 4-pole three-phase induction machine operated with different load cycles reveals the significant real and reactive power savings that could be obtained in the present proposal.

  9. Effect of tides, river flow, and gate operations on entrainment of juvenile salmon into the interior Sacramento–San Joaquin River Delta

    Science.gov (United States)

    Perry, Russell W.; Brandes, Patricia L.; Burau, Jon R.; Sandstrom, Philip T.; Skalski, John R.

    2015-01-01

    Juvenile Chinook Salmon Oncorhynchus tshawytscha emigrating from natal tributaries of the Sacramento River, California, must negotiate the Sacramento-San Joaquin River Delta (hereafter, the Delta), a complex network of natural and man-made channels linking the Sacramento River with San Francisco Bay. Fish that enter the interior and southern Delta—the region to the south of the Sacramento River where water pumping stations are located—survive at a lower rate than fish that use alternative migration routes. Consequently, total survival decreases as the fraction of the population entering the interior Delta increases, thus spurring management actions to reduce the proportion of fish that are entrained into the interior Delta. To better inform management actions, we modeled entrainment probability as a function of hydrodynamic variables. We fitted alternative entrainment models to telemetry data that identified when tagged fish in the Sacramento River entered two river channels leading to the interior Delta (Georgiana Slough and the gated Delta Cross Channel). We found that the probability of entrainment into the interior Delta through both channels depended strongly on the river flow and tidal stage at the time of fish arrival at the river junction. Fish that arrived during ebb tides had a low entrainment probability, whereas fish that arrived during flood tides (i.e., when the river's flow was reversed) had a high probability of entering the interior Delta. We coupled our entrainment model with a flow simulation model to evaluate the effect of nighttime closures of the Delta Cross Channel gates on the daily probability of fish entrainment into the interior Delta. Relative to 24-h gate closures, nighttime closures increased daily entrainment probability by 3 percentage points on average if fish arrived at the river junction uniformly throughout the day and by only 1.3 percentage points if 85% of fish arrived at night. We illustrate how our model can be used to

  10. Formation of conjugated delta8,delta10-double bonds by delta12-oleic-acid desaturase-related enzymes: biosynthetic origin of calendic acid.

    Science.gov (United States)

    Cahoon, E B; Ripp, K G; Hall, S E; Kinney, A J

    2001-01-26

    Divergent forms of the plant Delta(12)-oleic-acid desaturase (FAD2) have previously been shown to catalyze the formation of acetylenic bonds, epoxy groups, and conjugated Delta(11),Delta(13)-double bonds by modification of an existing Delta(12)-double bond in C(18) fatty acids. Here, we report a class of FAD2-related enzymes that modifies a Delta(9)-double bond to produce the conjugated trans-Delta(8),trans-Delta(10)-double bonds found in calendic acid (18:3Delta(8trans,10trans,12cis)), the major component of the seed oil of Calendula officinalis. Using an expressed sequence tag approach, cDNAs for two closely related FAD2-like enzymes, designated CoFADX-1 and CoFADX-2, were identified from a C. officinalis developing seed cDNA library. The deduced amino acid sequences of these polypeptides share 40-50% identity with those of other FAD2 and FAD2-related enzymes. Expression of either CoFADX-1 or CoFADX-2 in somatic soybean embryos resulted in the production of calendic acid. In embryos expressing CoFADX-2, calendic acid accumulated to as high as 22% (w/w) of the total fatty acids. In addition, expression of CoFADX-1 and CoFADX-2 in Saccharomyces cerevisiae was accompanied by calendic acid accumulation when induced cells were supplied exogenous linoleic acid (18:2Delta(9cis,12cis)). These results are thus consistent with a route of calendic acid synthesis involving modification of the Delta(9)-double bond of linoleic acid. Regiospecificity for Delta(9)-double bonds is unprecedented among FAD2-related enzymes and further expands the functional diversity found in this family of enzymes.

  11. Variations in growth, survival and carbon isotope composition (delta(13)C) among Pinus pinaster populations of different geographic origins.

    Science.gov (United States)

    Correia, Isabel; Almeida, Maria Helena; Aguiar, Alexandre; Alía, Ricardo; David, Teresa Soares; Pereira, João Santos

    2008-10-01

    To evaluate differences in growth and adaptability of maritime pine (Pinus pinaster Ait.), we studied growth, polycyclism, needle tissue carbon isotope composition (delta(13)C) as an estimate of water-use efficiency (WUE) and survival of seven populations at 10 years of age growing in a performance trial at a provenance test site in Escaroupim, Portugal. Six populations were from relatively high rainfall sites in Portugal and southwestern France (Atlantic group), and one population was from a more arid Mediterranean site in Spain. There were significant differences between some populations in total height, diameter at breast height, delta(13)C of bulk needle tissue, polycyclism and survival. A population from central Portugal (Leiria, on the Atlantic coast) was the tallest and had the lowest delta(13)C. Overall, the variation in delta(13)C was better explained by the mean minimum temperatures of the coldest month than by annual precipitation at the place of origin. Analyses of the relationships between delta(13)C and growth or survival revealed a distinct pattern for the Mediterranean population, with low delta(13)C (and WUE) associated with the lowest growth potential and reduced survival. There were significant negative correlations between delta(13)C and height or survival in the Atlantic group. Variation in polycyclism was correlated with annual precipitation at the place of origin. Some Atlantic populations maintained a high growth potential while experiencing moderate water stress. A detailed knowledge of the relationships between growth, survival and delta(13)C in contrasting environments will enhance our ability to select populations for forestry or conservation.

  12. Investigating fluvial pattern and delta-planform geometry based on varying intervals of flood and interflood

    Science.gov (United States)

    Rambo, J. E.; Kim, W.; Miller, K.

    2017-12-01

    Physical modeling of a delta's evolution can represent how changing the intervals of flood and interflood can alter a delta's fluvial pattern and geometry. Here we present a set of six experimental runs in which sediment and water were discharged at constant rates over each experiment. During the "flood" period, both sediment and water were discharged at rates of 0.25 cm3/s and 15 ml/s respectively, and during the "interflood" period, only water was discharged at 7.5 ml/s. The flood periods were only run for 30 minutes to keep the total volume of sediment constant. Run 0 did not have an interflood period and therefore ran with constant sediment and water discharge for the duration of the experiment.The other five runs had either 5, 10, or 15-min intervals of flood with 5, 10, or 15-min intervals of interflood. The experimental results show that Run 0 had the smallest topset area. This is due to a lack of surface reworking that takes place during interflood periods. Run 1 had 15-minute intervals of flood and 15-minute intervals of interflood, and it had the largest topset area. Additionally, the experiments that had longer intervals of interflood than flood had more elongated delta geometries. Wetted fraction color maps were also created to plot channel locations during each run. The maps show that the runs with longer interflood durations had channels occurring predominantly down the middle with stronger incisions; these runs produced deltas with more elongated geometries. When the interflood duration was even longer, however, strong channels started to occur at multiple locations. This increased interflood period allowed for the entire area over the delta's surface to be reworked, thus reducing the downstream slope and allowing channels to be more mobile laterally. Physical modeling of a delta allows us to predict a delta's resulting geometry given a set of conditions. This insight is needed especially with delta's being the home to many populations of people and

  13. Improved γ-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases.

    Science.gov (United States)

    Zhang, Yao; Luan, Xiao; Zhang, Huaiyuan; Garre, Victoriano; Song, Yuanda; Ratledge, Colin

    2017-06-21

    γ-Linolenic acid (GLA) is important because of its nutritional value and medicinal applications. Although the biosynthetic pathways of some plant and microbial GLA have been deciphered, current understanding of the correlation between desaturases and GLA synthesis in oleaginous fungi is incomplete. In previous work, we found that a large amount of oleic acid (OA) had not been converted to linoleic acid (LA) or GLA in Mucor circinelloides CBS 277.49, which may be due to inadequate activities of the delta-12 or delta-6 desaturases, and thus leading to the accumulation of OA and LA. Thus, it is necessary to explore the main contributing factor during the process of GLA biosynthesis in M. circinelloides. To enhance GLA production in M. circinelloides, homologous overexpression of delta-12 and two delta-6 desaturases (named delta-6-1 and delta-6-2, respectively) were analyzed. When delta-6 desaturase were overexpressed in M. circinelloides, up to 43% GLA was produced in the total fatty acids, and the yield of GLA reached 180 mg/l, which were, respectively, 38 and 33% higher than the control strain. These findings revealed that delta-6 desaturase (especially for delta-6-1 desaturase) plays an important role in GLA synthesis by M. circinelloides. The strain overexpressing delta-6-1 desaturase may have potential application in microbial GLA production.

  14. Synoptic Lithostratigraphy of The Niger Delta

    International Nuclear Information System (INIS)

    Nwajide, C.S.

    2002-01-01

    The Tertiary Niger Delta is stratigraphically framed by the Dahomey, Anambra, Abakaliki, Afikpo and Calabar Flank basins. From the apex at Onitsha a fluvial plain splays southwards and translates progressively into a freshwater swamp, succeeded by a mangrove swamp belt. Along the coast is a strip of wave-washed barrier bars indented by large estuaries, fronted by submerged moth bars. Habitation in the delta is on levees, point bars, and barrier bars. These landforms provided the firm salients for buildings the ports that facilitated international trade from the pre-colonial times.There are four lithofacies-clean, pebbly, and muddy sandstones, and mudstones. Their subdivision, based on sedimentary structures, textures and fossil content yields twenty reservoir and seven nonreservoir classes. Their environments of deposition, identified using facies associations, fall into fluvial, wave-and tide-dominated, marginal, and shallow marine, with localised canyons incised into the delta front and filled with deeper marine facies.The reservoirs are composed of 70 90% quartz, 4 15% feldspar, and 3 13% clay matrix, with minor mica, bioclasts, carbonaceous debris, glauconite, and heavy minerals. Grain size varies from very fine to coarse and pebbly, implying the presence of sands of varying textural and compositional maturities. Silica, K-feldspar, and carbonates constitute the cements.Porosity in the reservoirs has remained about the same as at deposition due to low mechanical compaction occasioned by shallow burial. Meteoric water-flushed progradational sequence are characterised by cementation with quartz and kaolinite. In contrast, marine water-flushed transgressive sands show grain coating illite-smectite, chlorite and K-feldspar overgrowths

  15. Stratigraphy and Evolution of Delta Channel Deposits, Jezero Crater, Mars

    Science.gov (United States)

    Goudge, T. A.; Mohrig, D.; Cardenas, B. T.; Hughes, C. M.; Fassett, C. I.

    2017-01-01

    The Jezero impact crater hosted an open-basin lake that was active during the valley network forming era on early Mars. This basin contains a well exposed delta deposit at the mouth of the western inlet valley. The fluvial stratigraphy of this deposit provides a record of the channels that built the delta over time. Here we describe observations of the stratigraphy of the channel deposits of the Jezero western delta to help reconstruct its evolution.

  16. Super-delta: a new differential gene expression analysis procedure with robust data normalization.

    Science.gov (United States)

    Liu, Yuhang; Zhang, Jinfeng; Qiu, Xing

    2017-12-21

    Normalization is an important data preparation step in gene expression analyses, designed to remove various systematic noise. Sample variance is greatly reduced after normalization, hence the power of subsequent statistical analyses is likely to increase. On the other hand, variance reduction is made possible by borrowing information across all genes, including differentially expressed genes (DEGs) and outliers, which will inevitably introduce some bias. This bias typically inflates type I error; and can reduce statistical power in certain situations. In this study we propose a new differential expression analysis pipeline, dubbed as super-delta, that consists of a multivariate extension of the global normalization and a modified t-test. A robust procedure is designed to minimize the bias introduced by DEGs in the normalization step. The modified t-test is derived based on asymptotic theory for hypothesis testing that suitably pairs with the proposed robust normalization. We first compared super-delta with four commonly used normalization methods: global, median-IQR, quantile, and cyclic loess normalization in simulation studies. Super-delta was shown to have better statistical power with tighter control of type I error rate than its competitors. In many cases, the performance of super-delta is close to that of an oracle test in which datasets without technical noise were used. We then applied all methods to a collection of gene expression datasets on breast cancer patients who received neoadjuvant chemotherapy. While there is a substantial overlap of the DEGs identified by all of them, super-delta were able to identify comparatively more DEGs than its competitors. Downstream gene set enrichment analysis confirmed that all these methods selected largely consistent pathways. Detailed investigations on the relatively small differences showed that pathways identified by super-delta have better connections to breast cancer than other methods. As a new pipeline, super-delta

  17. Tracks, spurs, blobs and delta-rays

    International Nuclear Information System (INIS)

    Magee, J.L.; Chatterjee, A.

    1983-01-01

    The track of a high-energy particle is the collection of all transient species created by the particle in the total degradation of its energy. Visible electron tracks are called delta rays. A microscopic description of the track with all its knocked-out electrons leads to spurs, blobs, and short tracks. Energy deposition criteria for these three track entities are 6 to 100 eV, 100 to 500 eV, and 500 eV to 5 keV, respectively

  18. The situation in the Niger Delta

    International Nuclear Information System (INIS)

    Vitalis, E.

    2007-01-01

    An energy issue for the United States and a political challenge for Europe, Nigeria is experiencing growing instability and is on the verge of civil war; the ecosystem and the population of the Niger Delta are the main victims. The State, corrupt, is powerless to contain the rising violence and redistribute the proceeds of oil sales. It is high time for oil-consuming countries, starting with the United States, to concern themselves with stabilizing the region. Europe must contribute to the lasting development of this country. (author)

  19. CFD analysis of fin tube heat exchanger with a pair of delta winglet vortex generators

    International Nuclear Information System (INIS)

    Hwang, Seong Won; Kim, Dong Hwan; Min, June Kee; Jeong, Ji Hwan

    2012-01-01

    Among tubular heat exchangers, fin tube types are the most widely used in refrigeration and air-conditioning equipment. Efforts to enhance the performance of these heat exchangers included variations in the fin shape from a plain fin to a slit and louver type. In the context of heat transfer augmentation, the performance of vortex generators has also been investigated. Delta winglet vortex generators have recently attracted research interest, partly due to experimental data showing that their addition to fin-tube heat exchangers considerably reduces pressure loss at heat transfer capacity of nearly the same level. The efficiency of the delta winglet vortex generators widely varies depending on their size and shape, as well as the locations where they are implemented. In this paper, the flow field around delta winglet vortex generators in a common flow up arrangement was analyzed in terms of flow characteristics and heat transfer using computational fluid dynamics methods. Flow mixing due to vortices and delayed separation due to acceleration influence the overall fin performance. The fin with delta winglet vortex generators exhibited a pressure loss lower than that of a plain fin, and the heat transfer performance was enhanced at high air velocity or Reynolds number

  20. Possible adaptation measures of agriculture sector in the Nile Delta to climate change impacts

    Directory of Open Access Journals (Sweden)

    S. M. Attaher

    2009-10-01

    Full Text Available The overall agricultural system in the Nile Delta region is considered as one of the highest intensive and complicated agriculture systems in the world. According to the recent studies, the Nile Delta region is one of the highly vulnerable regions in the world to climate change. Sea level rise, soil and water degradation, undiversified crop-pattern, yield reduction, pests and disease severity, and irrigation and drainage management were the main key factors that increased vulnerability of the agriculture sector in that region. The main objective of this study is to conduct a community-based multi-criteria adaptation assessment in the Nile Delta using a preset questionnaire. A list of possible adaptation measures for agriculture sector was evaluated. The results indicated that the Nile Delta growers have strong perceptions to act positively to reduce the impacts of climate change. They reflected the need to improve the their adaptive capacity based on clear scientific message with adequate governmental support to coop with the negative impacts of climate change.

  1. THE HIDROLOGICAL RELATIONSHIP BETWEEN DANUBE ARMS AND LAKE COMPLEXIS IN THE DANUBE DELTA

    Directory of Open Access Journals (Sweden)

    Basarab Victor DRIGA

    2008-06-01

    Full Text Available The Danube Delta, which is an open system, is permanently exchanging matter and energy with the external environment. The hydrological sub-system, basically the water circulation represents the vital component of the existence of the delta space. In view of the ecological requirements of this delta space, of the present and prospective situation of various managements, of the present legal framework and the future of the Danube Delta Biosphere Reserve, it is advisable to make some changes to the water circulation system within the Letea unit as follows: to close down or undersize the Mila 35 Canal and the Mila 22 Canal, to reduce the Crânjală Canal flow section or close the canal, to secure the ecological reconstruction of inefficient dammed enclosures (e.g. Pardina by ensuring normal water circulation inside them, to reopen the Sireasa Canal at its junction with the Chilia Arm. The fact is that the water circulation system throughout the Caraorman unit will suffer essential changes, so that is recommendable to: revitalise the Litcov Canal and close the Filat canal, downsize the Crişan-Caraorman flow section, open up the Gorgova and Ceamurlia canals, revigorate the Ivancea and the Erenciuc canals (between the Puiu and the Erenciuc lakes, respectively, make 2 – 3 openings in the littoral dam and in the Împuţita Backwater, placing the weir level at + 70-80 cm, in order to facilitate the depression water outflow into the sea.

  2. CFD analysis of fin tube heat exchanger with a pair of delta winglet vortex generators

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Seong Won; Kim, Dong Hwan; Min, June Kee; Jeong, Ji Hwan [Pusan National Univ., Busan (Korea, Republic of)

    2012-09-15

    Among tubular heat exchangers, fin tube types are the most widely used in refrigeration and air-conditioning equipment. Efforts to enhance the performance of these heat exchangers included variations in the fin shape from a plain fin to a slit and louver type. In the context of heat transfer augmentation, the performance of vortex generators has also been investigated. Delta winglet vortex generators have recently attracted research interest, partly due to experimental data showing that their addition to fin-tube heat exchangers considerably reduces pressure loss at heat transfer capacity of nearly the same level. The efficiency of the delta winglet vortex generators widely varies depending on their size and shape, as well as the locations where they are implemented. In this paper, the flow field around delta winglet vortex generators in a common flow up arrangement was analyzed in terms of flow characteristics and heat transfer using computational fluid dynamics methods. Flow mixing due to vortices and delayed separation due to acceleration influence the overall fin performance. The fin with delta winglet vortex generators exhibited a pressure loss lower than that of a plain fin, and the heat transfer performance was enhanced at high air velocity or Reynolds number.

  3. Adaptive delta management: a comparison between the Netherlands and Bangladesh Delta Program

    NARCIS (Netherlands)

    Zevenbergen, Chris; Khan, Shah Alam; Alphen, van Jos; Terwisscha van Scheltinga, Catharien; Veerbeek, William

    2018-01-01

    In the Netherlands, the central government, water authorities, provinces and municipalities are working together on a new Delta Program on Flood Risk Management and Fresh Water Supply (DP). Its primary goal is to protect the Netherlands against floods and ensure the availability of fresh water, now

  4. Tidal modulated flow and sediment flux through Wax Lake Delta distributary channels: Implications for delta development

    Directory of Open Access Journals (Sweden)

    K. Hanegan

    2015-03-01

    Full Text Available In this study, a Delft3D model of the Wax Lake Delta was developed to simulate flow and sediment flux through delta distributary channels. The model was calibrated for tidal constituents as well as velocity and sediment concentration across channel transects. The calibrated model was then used to simulate full spring–neap tidal cycles under constant low flow upstream boundary conditions, with grain size variation in suspended load represented using two sediment fractions. Flow and sediment flux results through distributary channel cross-sections were examined for spatial and temporal variability with the goal of characterizing the role of tides in sediment reworking and delta development. The Wax Lake Delta has prograded through channel extension, river mouth bar deposition, and channel bifurcation. Here we show that tidal modulation of currents influences suspended sand transport, and spatial acceleration through distributary channels at low tides is sufficient to suspend sand in distal reaches during lower flows. The basinward-increasing transport capacity in distributary channels indicates that erosive channel extension could be an important process, even during non-flood events.

  5. Delta Plaza kohvik = The Delta Plaza Café / Margit Mutso

    Index Scriptorium Estoniae

    Mutso, Margit, 1966-

    2010-01-01

    Tallinnas Pärnu mnt. 141 asuva kohviku Delta Plaza sisekujundusest. Sisearhitektid Tiiu Truus ja Marja Viltrop (Stuudio Truus OÜ). Hoone arhitektid Jüri Okas ja Marika Lõoke (AB J. Okas & M. Lõoke). Žürii liikme Mait Summataveti arvamus kohvikust

  6. Studying medium effects with the optimized {delta} expansion

    Energy Technology Data Exchange (ETDEWEB)

    Krein, G [Instituto de Fisica Teorica (IFT), Sao Paulo, SP (Brazil); Menezes, D P [Santa Catarina Univ., Florianopolis, SC (Brazil). Dept. de Fisica; Nielsen, M [Sao Paulo Univ., SP (Brazil). Inst. de Fisica; Pinto, M B [Montpellier-2 Univ., 34 (France). Lab. de Physique Mathematique

    1995-04-01

    The possibility of using the optimized {delta} expansion for studying medium effects on hadronic properties in quark or nuclear matter is investigated. The {delta} expansion is employed to study density effects with two commonly used models in hadron and nuclear physics, the Nambu-Jona-Lasinio model for the dynamical chiral symmetry breaking and the Walecka model for the equation of state of nuclear matter. The results obtained with the {delta} expansion are compared to those obtained with the traditional Hartree-Fock approximation. Perspectives for using the {delta} expansion in other field theoretic models in hadron and nuclear physics are discussed. (author). 17 refs, 9 figs.

  7. Optimality and self-organization in river deltas

    Science.gov (United States)

    Tejedor, A.; Longjas, A.; Edmonds, D. A.; Zaliapin, I. V.; Georgiou, T. T.; Rinaldo, A.; Foufoula-Georgiou, E.

    2017-12-01

    Deltas are nourished by channel networks, whose connectivity constrains, if not drives, the evolution, functionality and resilience of these systems. Understanding the coevolution of deltaic channels and their flux organization is crucial for guiding maintenance strategies of these highly stressed systems from a range of anthropogenic activities. However, in contrast to tributary channel networks, to date, no theory has been proposed to explain how deltas self-organize to distribute water and sediment to the delta top and the shoreline. Here, we hypothesize the existence of an optimality principle underlying the self-organized partition of fluxes in delta channel networks. Specifically, we hypothesize that deltas distribute water and sediment fluxes on a given delta topology such as to maximize the diversity of flux delivery to the shoreline. By introducing the concept of nonlocal Entropy Rate (nER) and analyzing ten field deltas in diverse environments, we present evidence that supports our hypothesis, suggesting that delta networks achieve dynamically accessible maxima of their nER. Furthermore, by analyzing six simulated deltas using the Delf3D model and following their topologic and flux re-organization before and after major avulsions, we further study the evolution of nER and confirm our hypothesis. We discuss how optimal flux distributions in terms of nER, when interpreted in terms of resilience, are configurations that reflect an increased ability to withstand perturbations.

  8. Upper-division student difficulties with the Dirac delta function

    Directory of Open Access Journals (Sweden)

    Bethany R. Wilcox

    2015-03-01

    Full Text Available The Dirac delta function is a standard mathematical tool that appears repeatedly in the undergraduate physics curriculum in multiple topical areas including electrostatics, and quantum mechanics. While Dirac delta functions are often introduced in order to simplify a problem mathematically, students still struggle to manipulate and interpret them. To characterize student difficulties with the delta function at the upper-division level, we examined students’ responses to traditional exam questions and a standardized conceptual assessment, and conducted think-aloud interviews. Our analysis was guided by an analytical framework that focuses on how students activate, construct, execute, and reflect on the Dirac delta function in the context of problem solving in physics. Here, we focus on student difficulties using the delta function to express charge distributions in the context of junior-level electrostatics. Common challenges included invoking the delta function spontaneously, translating a description of a charge distribution into a mathematical expression using delta functions, integrating 3D or non-Cartesian delta function expressions, and recognizing that the delta function can have units. We also briefly discuss implications of these difficulties for instruction.

  9. Catalyzing action towards the sustainability of deltas: deltas as integrated socio-ecological systems and sentinels of regional and global change

    Science.gov (United States)

    Foufoula-Georgiou, E.; Tessler, Z. D.; Brondizio, E.; Overeem, I.; Renaud, F.; Sebesvari, Z.; Nicholls, R. J.; Anthony, E.

    2016-12-01

    Deltas are highly dynamic and productive environments: they are food baskets of the world, home to biodiverse and rich ecosystems, and they play a central role in food and water security. However, they are becoming increasingly vulnerable to risks arising from human activities, land subsidence, regional water management, global sea-level rise, and climate extremes. Our Belmont Forum DELTAS project (BF-DELTAS: Catalyzing actions towards delta sustainability) encompasses an international network of interdisciplinary research collaborators with focal areas in the Mekong, Ganges Brahmaputra, and the Amazon deltas. The project is organized around five main modules: (1) developing an analytical framework for assessing delta vulnerability and scenarios of change (Delta-SRES), (2) developing an open-acess, science-based integrative modeling framework for risk assessment and decision support (Delta-RADS), (3) developing tools to support quantitative mapping of the bio-physical and socio-economic environments of deltas and consolidate bio-physical and social data within shared data repositories (Delta-DAT), (4) developing Global Delta Vulnerability Indices (Delta-GDVI) that capture current and projected scenarios for major deltas around the world , and (5) collaborating with regional stakeholders to put the science, modeling, and data into action (Delta-ACT). In this talk, a research summary will be presented on three research domains around which significant collaborative work was developed: advancing biophysical classification of deltas, understanding deltas as coupled socio-ecological systems, and analyzing and informing social and environmental vulnerabilities in delta regions.

  10. HSE (CASHES) management in Niger Delta seismic operations

    Energy Technology Data Exchange (ETDEWEB)

    Adepoju, O.J.

    1996-12-31

    3-D seismic acquisition surveys in the Niger Delta of Nigeria, are carried out under extremely arduous field conditions due to difficult terrain, dense vegetation, semi-manual mode of operation, wildlife and volatile communities. The vegetation is a combination of evergreen tropical rain forest in the land areas and mangrove in the swamp areas. Some parts of the delta are prone to high seasonal flooding. Seismic lines are laid out by manual cutting of brush using machetes and shot holes drilled semi-manually with pumps. In order to effectively carry out the operations with due regard to the people and environment, a Community Affairs, Safety, Health, Environment and Security (CASHES) Polio and management System which ensures that a hazards are identified, assessed. controlled, with an effective loop feedback mechanism was introduced and implemented. CASHES critical activities are community relations, field security, explosives handling, water transport/journey management, river crossings. weather, shallow gas blow-out, waste management, seasonal flooding and floating-seaweed (water hyacinth)/timber logs. Environmental Impact Assessment (EIA) studies arc essential at the initial planning stages. About 41 Hazard Registers and 177 Activity Specification Sheets are developed in a typical survey. About 85% of the labor workforce are recruited from the host communities to promote cordial relations. Extensive training is carried out to raise the standards of the new recruits. The implementation of the management system is cascaded down using simplified documentation (procedures, work tasks, checklists etc.) adapted to local conditions. Integrated CASHES audits (Premob, Minor, Major. Follow up) arc conducted to check the efficiency of the system with documents getting reviewed regularly to keep the system alive and capable of handling changes. With these in place, high potential incidents are reduced/eliminated.

  11. Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial

    NARCIS (Netherlands)

    Lincoff, A.M.; Roe, M.; Aylward, P.; Galla, J.; Rynkiewicz, A.; Guetta, V.; Zelizko, M.; Kleiman, N.; White, H.; McErlean, E.; Erlinge, D.; Laine, M.; Ferreira, J.M. Dos Santos; Goodman, S.; Mehta, S.; Atar, D.; Suryapranata, H.; Jensen, S.E.; Forster, T.; Fernandez-Ortiz, A.; Schoors, D.; Radke, P.; Belli, G.; Brennan, D.; Bell, G.; Krucoff, M.; et al.,

    2014-01-01

    AIMS: Delcasertib is a selective inhibitor of delta-protein kinase C (delta-PKC), which reduced infarct size during ischaemia/reperfusion in animal models and diminished myocardial necrosis and improved reperfusion in a pilot study during primary percutaneous coronary intervention (PCI) for ST

  12. The Dokka delta - consequences of water power development in the River Dokka

    International Nuclear Information System (INIS)

    Halvorsen, Gunnar; Sloreid, Svein-Erik; Walseng, Bjoern

    1997-11-01

    The report concerns an investigation done in Norway on environmental consequences of hydroelectric power development in the Dokka river. This development has reduced the water flow through the Dokka delta to about 50% of its natural level. The biological effect of the reduction has been studied in the period from 1987 to 1990, comprising two years before and two years after the reduction. Sedimentation, water chemistry, planktonic and littoral crustaceans and bottom fauna have been studied. 223 refs., 58 figs., 9 tabs

  13. Superconducting bandpass delta-sigma modulator

    International Nuclear Information System (INIS)

    Bulzacchelli, J.F.; Lee, H.-S.; Misewich, J.A.; Ketchen, M.B.

    1999-01-01

    Bandpass delta-sigma modulators digitize narrowband signals with high dynamic range and linearity. The required sampling rate is only a few times higher than the centre frequency of the input. This paper presents a superconducting bandpass delta-sigma modulator for direct analogue-to-digital conversion of RF signals in the GHz range. The input signal is capacitively coupled to one end of a microstrip transmission line, and a single flux quantum balanced comparator quantizes the current flowing out of the other end. Quantization noise is suppressed at the quarter-wave resonance of the transmission line (about 2 GHz in our design). Circuit performance at a 20 GHz sampling rate has been studied with several long JSIM simulations. Full-scale (FS) input sensitivity is 20 mV (rms), and in-band noise is -53 dBFS and -57 dBFS over bandwidths of 39 MHz and 19.5 MHz, respectively. In-band intermodulation distortion is better than -69 dBFS. (author)

  14. Subcatchment deltas and upland features influence multiscale aquatic ecosystem recovery in damaged landscapes.

    Science.gov (United States)

    Kielstra, Brian W; Arnott, Shelley E; Gunn, John M

    2017-12-01

    Assessing biological recovery in damaged aquatic environments requires the consideration of multiple spatial and temporal scales. Past research has focused on assessing lake recovery from atmospheric or catchment disturbance at regional or catchment levels. Studies have also rarely considered the influences of adjacent terrestrial characteristics on within-lake habitats, such as subcatchment delta confluences. We used Hyalella azteca, a ubiquitous freshwater amphipod, as a sensitive indicator to assess the importance of local subcatchment scale factors in the context of multiscale lake recovery within the metal mining region of Sudbury, Canada following a period of major reductions in atmospheric pollution. At the regional scale, data from repeated surveys of 40 lakes showed higher probabilities of H. azteca occurrence with higher lake water conductivity, alkalinity, and pH and lower metal concentrations. The importance of metals decreased through time and the importance of higher conductivity, alkalinity, and pH increased. At the subcatchment scale, a subset of six lakes sampled across a colonization gradient revealed higher H. azteca abundances at subcatchment delta sites than non-delta sites in early colonization stages, and that abundance at delta sites was correlated with both within-lake habitat and terrestrial subcatchment characteristics. For example, wetland cover reduced the strength of positive associations between H. azteca abundance and macrophyte density. A single lake from this subset also revealed higher abundances at delta sites associated with higher concentrations of terrestrial organic matter and larger subcatchments. Our results demonstrate that factors affecting recovery can change with the scale of study, and that managing terrestrial-aquatic linkages is important for facilitating recovery processes within damaged lake ecosystems. © 2017 by the Ecological Society of America.

  15. Electronic Structure of TlBa2CaCu2O(7-Delta)

    Science.gov (United States)

    Vasquez, R. P.; Novikov, D. L.; Freeman, A. J.; Siegal, M. P.

    1997-01-01

    The core levels of TlBa2CaCu2O(7-delta) (Tl-1212) epitaxial films have been measured with X-ray photoelectron spectroscopy (XPS). The valence electronic structure has been determined using the full-potential linear muffin-tin-orbital band-structure method and measured with XPS. The calculations show that a van Hove singularity (VHS) lies above the Fermi level (E(sub F)) for the stoichiometric compound (delta = 0.5), while for 50% oxygen vacancies in the Tl-O layer (delta = 0.5) E(sub F) is in close proximity to the VHS. Samples annealed in nitrogen (to reduce the hole overdoping by the removal of oxygen) exhibit higher core-level binding energies and a higher T(sub c), consistent with a shift of E(sub F) closer to the VHS. Comparisons are made to the core levels and valence bands of Tl2Ba2CaCu2O(8 + delta)(Tl-2212) and HgBa2CaCu2O)6 + delta) (Hg- 1212). The similarity of the Cu 2p(sub 3/2) spectra for Tl-1212 and Tl-2212 indicates that the number of Tl-O layers has little effect on the Cu-O bonding. However, the Tl-1212 and Hg-1212 Cu 2p(sub 3/2) signals exhibit differences which suggest that the replacement of T(sup 3+) with Hg(sup 2+) results in a decrease in the O 2p right arrow Cu 3d charge-transfer energy and differences in the probabilities of planar vs apical oxygen charge transfer and/or Zhang-Rice singlet-state formation. Differences between the Tl-1212 and the Tl-2212 and Hg-1212 measured valence bands are consistent with the calculated Cu 3d and (Tl,Hg) 6s/5d partial densities of states.

  16. Facilitating Adaptive Management in California’s Sacramento–San Joaquin Delta

    Directory of Open Access Journals (Sweden)

    John A. Wiens

    2017-07-01

    Full Text Available https://doi.org/10.15447/sfews.2017v15iss2art3Uncertainties in understanding ecosystems increase the risk that management will fail to achieve desired results. Adaptive management is a structured, iterative application of science-based knowledge to reduce uncertainties and build flexibility into decision-making. However, adaptive management is more easily planned than implemented, and it is only beginning to be applied in the California’s Sacramento–San Joaquin Delta. We draw from two assessments of adaptive management in the Delta and examples of its use elsewhere to suggest how the process can be facilitated. Although a highly structured adaptive-management process may not always be needed, several elements are essential. Adaptive management should begin by clearly identifying the problem, goals, and objectives; recognizing uncertainties; identifying decision points and alternative approaches; recognizing when adjustments are needed and having the flexibility to make them; and considering societal and political constraints. Model complexity should be matched to that of the system and management needs; experiments can help unravel causal relationships. Monitoring, analyses, and syntheses require comprehensive data-management systems. More frequent and organized communications among scientists, managers, stakeholders, and decision-makers are necessary. We propose the establishment of an “Adaptive Management Team” to coordinate efforts across the management spectrum of the Delta and to provide guidance and link individual projects to shared approaches and experiences. Reliable long-term support will be needed to assess results of management actions, adjust approaches where improvement is likely, and strive toward the legislated goals of enhancing the Delta ecosystem while also providing reliable water supplies to much of California, and doing both these things in a manner that protects values of the Delta as a place where people live and

  17. One-step synthesis of delta-MnO2 nanoparticles using ascorbic acid and their scavenging properties to Pb(II), Zn(II) and methylene blue

    NARCIS (Netherlands)

    Wang, M.X.; Pang, P.; Koopal, L.K.; Qiu, G.H.; Wang, Y.; Liu, F.

    2014-01-01

    To obtain delta-MnO2 particles with a large specific surface area, MnO2 was synthesized in an ice-water bath using ascorbic acid (AA) to reduce KMnO4. At pH 3 and 5 and KMnO4/AA molar ratios of 8/1 and 10/1, nanoparticles of delta-MnO2 were produced. The specific surface areas (SSAs) of the samples

  18. Impacts of climate change on rainfall, seasonal flooding, and evapotranspiration in the Okavango Delta, Botswana

    Science.gov (United States)

    Konecky, B. L.; Noone, D.; Mosimanyana, E.; Gondwe, M.

    2016-12-01

    The Okavango Delta in northern Botswana is one of the world's richest biodiversity hotspots. A UNESCO World Heritage Site, the Delta is known for its unique annual flood pulse, whereby the wetland and its neighboring river systems are inundated with waters that travel nearly 1000 km before reaching this subtropical, semi-arid destination. The livelihoods of northern Botswana's ecosystems and human populations rely on these floods to supplement the short and variable rainy season, which in many years is too minimal to ameliorate regional drought. However, anthropogenic climate change is reducing the amount of water that reaches the delta by increasing evaporation from soils and rivers, and transpiration by vegetation, during its long transit to Botswana. Future changes in rainfall patterns, extreme events, and increased upstream water use could exacerbate this water stress. Unfortunately, it remains difficult to assess the impacts of climate change on the delta because few data exist to constrain its complex climatic and seasonal water cycling regimes. This study presents a novel characterization of the water cycle in and around the Okavango Delta based on a survey of free-flowing surface waters, stagnant pools, precipitation, and groundwater carried out during the 2016 rainy and early-flood season. We use stable isotope and water quality data to assess local moisture sources, transport, evaporation, wetland flushing, and land-atmosphere exchanges, all of which are subject to change under global warming. We find a strong evaporation gradient and a progressive flushing of stagnant swamp waters along the northeastern and northwestern channels of the Delta. The evaporation gradient is more limited in nearby rivers with more limited wetlands. We contrast results with a survey of the Delta performed in the 1970's in order to assess changes over the past 40 years. Since some of these changes may arise from rainfall supply, we also present new analysis of rainfall moisture

  19. The Concentration Dependence of the (Delta)s Term in the Gibbs Free Energy Function: Application to Reversible Reactions in Biochemistry

    Science.gov (United States)

    Gary, Ronald K.

    2004-01-01

    The concentration dependence of (delta)S term in the Gibbs free energy function is described in relation to its application to reversible reactions in biochemistry. An intuitive and non-mathematical argument for the concentration dependence of the (delta)S term in the Gibbs free energy equation is derived and the applicability of the equation to…

  20. Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments

    NARCIS (Netherlands)

    Baer, R.; Boehm, T.; Yssel, H.; Spits, H.; Rabbitts, T. H.

    1988-01-01

    We have examined DNA rearrangements within a 120 kb cloned region of the human T cell receptor J delta-C delta/J alpha-C alpha locus. Three types of pattern emerge from an analysis of T cell lines and clones. Firstly, cells with two rearrangements within J delta-C delta; secondly, cells with one

  1. Spatio-temporal distributions of delta18O, delta D and salinity in the Arabian Sea: Identifying processes and controls

    Digital Repository Service at National Institute of Oceanography (India)

    Deshpande, R.D; Muraleedharan, P.M.; Singh, R.L.; Kumar, B.; Rao, M.S.; Dave, M.; Sivakumar, K.U.; Gupta, S.K.

    the geographic distributions of the delta18O and S; (2) in spite of a large scatter, a statistically significant delta18O–S relationship can be identified in much of the investigated part of the AS; (3) the delta18Odelta...

  2. 78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

    Science.gov (United States)

    2013-04-10

    ... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662, 02/02-0661] DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint...

  3. Changes to subaqueous delta bathymetry following a high river flow event, Wax Lake Delta, LA, USA

    Science.gov (United States)

    Whaling, A. R.; Shaw, J.

    2017-12-01

    Sediment transport capacity is increased during high river flow (flood) events which are characterized by discharges that exceed the 15 year median daily statistic. The Wax Lake Delta (WLD) in coastal Louisiana has experienced 19 of these high flow events in the past 20 years, yet the depositional patterns of single floods are rarely measured in a field-scale deltaic setting. We characterize flood deposition and erosion patterns on the subaqueous portion of the WLD by differencing two Digital Elevation Models (DEMs) constructed from bathymetric surveys before and after the third largest flood in the WLD's recorded history. The total suspended sediment discharge for the 496 day inter-survey period was 2.14x107 cubic meters measured 21 km upstream of the delta apex. The difference map showed 1.06x107 cubic meters of sediment was deposited and 8.2x106 cubic meters was eroded, yielding 2.40x106 cubic meters of net deposition in the survey area ( 79.7 km2 ). Therefore the average deposition rate was 0.061 mm/day. Channel planform remained relatively unchanged for five out of six distributary passes however Gadwall Pass experienced a maximum channel displacement of 166 m ( 1 channel width) measured from the thalweg centerline. Channel tip extension was negligible. In addition, channel displacement was not concentrated at any portion along the channel centerline. Maximum erosion occurred within channel margins and increased upstream whereas maximum deposition occurred immediately outside the channel margins. Sediment eroded from the survey area was either subsequently re-deposited or transported out of the system. Our results show that up to 77.4% of deposition in the survey area originated from sediment eroded during the flood. Surprisingly, only 11.2% of the total suspended sediment discharge was retained in the subaqueous portion of the delta after the flood. We conclude that a high flow event does not produce channel progradation. Rather, high flow causes delta

  4. Effect mechanism of air deflectors on the cooling performance of dry cooling tower with vertical delta radiators under crosswind

    International Nuclear Information System (INIS)

    Zhao, Yuanbin; Long, Guoqing; Sun, Fengzhong; Li, Yan; Zhang, Cuijiao; Liu, Jiabin

    2015-01-01

    Highlights: • A 3D numerical model was set for NDDCTV to study the effect of air deflectors. • The air deflectors improve the tower performance by 1.375 °C at u c = 6 m/s for a case. • The air deflectors reduce the air inflow deviation angle θ d at most delta entries. • The reduced θ d can improve the cooling performance of former deteriorated columns. • Both the radial inflow air velocity and θ d impact the cooling performance of delta. - Abstract: To study the effect mechanism of air deflectors on dry cooling tower, a three dimensional numerical model was established, with full consideration of the delta structure. The accuracy and credibility of dry cooling tower numerical model were validated. By numerical model, the average air static pressure and the average radial inflow air velocity were computed and analyzed at delta air entry, sector air entry and exit faces. By the air inflow deviation angle θ d , the effect of air deflectors on the aerodynamic field around tower was analyzed. The water exit temperatures of θ −1 columns, θ +2 columns and cooling sectors were also presented to clarify the effect of air deflectors. It was found that the air deflectors improved the aerodynamic field around cooling columns. The reduced air inflow deviation degree at delta entry improved the cooling performance of deteriorated columns. Referring to the radial inflow air velocity u ra and the air inflow deviation degree at delta entry, the effect mechanism of air deflectors are clarified under crosswind

  5. Niger Delta Crisis and Security Implications for the Nation State ...

    African Journals Online (AJOL)

    The Niger Delta is the nation's treasure base, the Niger Delta provides over 80 percent of government revenue, 95 percent of export receipts, and 90 percent of ... The government should tackle the fundamental issue of basic necessities – provision of good motorable roads, pipe borne water, electricity, good hospitals, good ...

  6. Morphodynamics of the Manyema tidal delta 1 LIST OF TABLES ...

    African Journals Online (AJOL)

    Kheira Kortenbout

    Morphodynamics of the Manyema tidal delta. 1. LIST OF ... Location of Manyema Creek and its associated tidal delta platform at Kunduchi. Fig. 2. ... platform. Beachcomber. Hotel. Whitesands. Hotel. Kunduchi. Beach Hotel. Giraffe. Hotel. INDIAN. OCEAN. Mombasa. Dar es. Salaam. KUNDUCHI. KENYA. TANZANIA.

  7. Towards a Comprehensive Framework for Adaptive Delta Management

    NARCIS (Netherlands)

    Marchand, M.; Ludwig, F.

    2014-01-01

    Deltas are dynamic landforms at the boundary of land and sea, involving intricate mazes of rivers and small waterways, wetlands, estuaries and coastal barrier islands. They are home to over half a billion people. Deltas are also home to rich ecosystems, such as mangroves and marshes. They are

  8. Conflict resolution among Niger delta communities: A historical ...

    African Journals Online (AJOL)

    Conflict related issues have assumed endemic proportion in the Niger Delta. A proper assessment of the critical factors in motion must take cognizance of their historical underpinnings. Peaceful co-existence, the hallmark of conflict resolution, can be feasible in the Niger Delta, through sustainable dialogue. These, among

  9. Upper-Division Student Difficulties with the Dirac Delta Function

    Science.gov (United States)

    Wilcox, Bethany R.; Pollock, Steven J.

    2015-01-01

    The Dirac delta function is a standard mathematical tool that appears repeatedly in the undergraduate physics curriculum in multiple topical areas including electrostatics, and quantum mechanics. While Dirac delta functions are often introduced in order to simplify a problem mathematically, students still struggle to manipulate and interpret them.…

  10. Caribbean piracy and youth restiveness in Niger delta: A ...

    African Journals Online (AJOL)

    Our aim in this paper is to make a comparative analysis of Caribbean piracy and youth restiveness in Niger Delta of Nigeria. It will not be out of place to carry out such an analysis having seen, heard or read of the ongoing chaos, insecurity in the. Niger Delta Zone in Nigeria. We have to look at the past to find out such similar

  11. 78 FR 45592 - DeltaPoint Capital IV, LP;

    Science.gov (United States)

    2013-07-29

    ..., Suite 160, Pittsford, NY 14534. The financing was contemplated for working capital. The financing is... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662] DeltaPoint Capital IV, LP; Notice Seeking... given that DeltaPoint Capital IV, L.P., 45 East Avenue, 6th Floor, Rochester, NY 14604, Federal...

  12. Central Delta languages: An overview | Kari | Stellenbosch Papers ...

    African Journals Online (AJOL)

    This paper presents an overview of the phonology, morphology and syntax of Central Delta languages. It also provides information on the geo-linguistic, demographic and sociolinguistic situation of these languages. It notes that Central Delta languages have a 20-vowel system, which divides into two sets of 10 vowels ...

  13. Downstream hydraulic geometry of a tidally influenced river delta

    NARCIS (Netherlands)

    Sassi, M.G.; Hoitink, A.J.F.; Brye, de B.; Deleersnijder, E.

    2012-01-01

    Channel geometry in tidally influenced river deltas can show a mixed scaling behavior between that of river and tidal channel networks, as the channel forming discharge is both of river and tidal origin. We present a method of analysis to quantify the tidal signature on delta morphology, by

  14. Delta: the first pion nucleon resonance - its discovery and applications

    International Nuclear Information System (INIS)

    Nagle, D.E.

    1984-07-01

    It is attempted to recapture some of the fun and excitement of the pion-scattering work that led to the discovery of what is now called the delta particle. How significant this discovery was became apparent only gradually. That the delta is alive today and thriving at Los Alamos (as well as other places) is described

  15. Wastewater disposal at safari lodges in the Okavango Delta, Botswana

    African Journals Online (AJOL)

    Wastewater disposal at safari lodges in the Okavango Delta, Botswana. TS McCarthy, T Gumbricht, RG Stewart, D Brandt, PJ Hancox, J McCarthy, AG Duse. Abstract. Many safari lodges in the Okavango Delta obtain their water supply from boreholes in near-surface aquifers while disposing of their wastewater via ...

  16. Quark sea and the. delta. I=1/2 rule

    Energy Technology Data Exchange (ETDEWEB)

    Donoghue, J F [Carnegie-Mellon Univ., Pittsburgh, Pa. (USA). Dept. of Physics; Golowich, E [Massachusetts Univ., Amherst (USA)

    1977-08-29

    The effect on nonleptonic processes of quark-antiquark pairs due to quantum chromodynamics is studied. Their presence improves agreement between theory and experiment for hyperon decays. In kaon decays a new ..delta..I=1/2 contribution is found, but ..delta..I=3/2 effects are still too large to be in agreement.

  17. Antinociceptive activity of Delta9-tetrahydrocannabinol non-ionic microemulsions.

    Science.gov (United States)

    Lazzari, P; Fadda, P; Marchese, G; Casu, G L; Pani, L

    2010-06-30

    Delta(9)-Tetrahydrocannabinol (Delta(9)-THC), the major psychoactive constituent of Cannabis sativa L., has been widely studied for its potential pharmaceutical application in the treatment of various diseases and disturbs. This sparingly soluble terpeno-phenolic compound is not easy to handle and to be formulated in pharmaceutical preparations. The aim of this work was to develop a stable aqueous Delta(9)-THC formulation acceptable for different ways of administration, and to evaluate the therapeutic properties of the new Delta(9)-THC based preparation for pain treatment. Due to the thermodynamic stability and advantages of microemulsion based systems, the study was focused on the identification of aqueous microemulsion based systems containing Delta(9)-THC. Oil in water Delta(9)-THC microemulsions were individuated through phase diagrams construction, using the non-ionic surfactant Solutol HS15, being this surfactant acceptable for parenteral administration in human. A selected microemulsion samples containing 0.2 wt% of Delta(9)-THC, stable up to 52 degrees C, was successfully assayed on animal models of pain. Significant antinociceptive activity has been detected by both intraperitoneal and intragastric administration of the new Delta(9)-THC pharmaceutical preparation. The effect has been highlighted in shorter time if compared to a preparation of the same active principle based on previously reported conventional preparation. 2010 Elsevier B.V. All rights reserved.

  18. An annotated list of Fishes from the Niger Delta

    NARCIS (Netherlands)

    Boeseman, M.

    1963-01-01

    At the end of November 1960, the Leiden Museum received an interesting collection of animals, mostly fishes, from the Niger delta. All specimens were collected by Mr. H. J. G. Beets, at the time employed by Shell B.P. — Delta Investigations, during the period May to August 1960, and in the region

  19. Topological Mappings via B&delta;g-Closed Sets

    OpenAIRE

    Maruthamuthu, Raja; Narayanasamy, Seenivasagan; Otchanathevar, Ravi

    2018-01-01

    In this paper we introduce a new class of functions called  B&delta;g-continuous functions. We obtain several characterizations and some their properties. Also we investigate its relationship with other types of functions. Further we introduce and study a new class of functions namely B&delta;g-irresolute.

  20. Estimation of Thermal Conductivity in the North- Western Niger Delta ...

    African Journals Online (AJOL)

    Thermal conductivity estimates are computed from nineteen petroleum wells in the north-western Niger Delta, Nigeria, using a geometric mean model. Sonic and gamma-ray logs were digitised and used in the estimation of in situ conductivity. The Niger Delta is composed of three major diachronous lithostratigraphic units of ...

  1. How to deal with subsidence in the Dutch delta?

    NARCIS (Netherlands)

    Stouthamer, E.; Erkens, G.

    2017-01-01

    In many deltas worldwide subsidence still is an underestimated problem, while the threat posed by land subsidence low-lying urbanizing and urbanized deltas exceeds the threat of sea-level rise induced by climate change. Human-induced subsidence is driven by the extraction of hydrocarbons and

  2. Dousing the tension in the Niger delta through administrative agency

    African Journals Online (AJOL)

    Dousing the tension in the Niger delta through administrative agency: A programme evaluation of Niger delta development commission as an intervention regime. ... the study concludes that because of systemic constraints arising from the hegemonic interests of the dominant coalitions in the Nigerian Social formation, ...

  3. Drones on the delta | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 nov. 2016 ... Waves wash ashore at Fuvemeh, a town in Ghana's Volta River delta that's threatened by coastal erosion and flooding. Brian Owens, Canadian Geographic. Ghana's Volta River delta is an area vulnerable to climate change, with rising seas and increasingly powerful storms driving flooding and erosion, ...

  4. Homosexuality amongst migrant oil workers in the Niger Delta ...

    African Journals Online (AJOL)

    Aims: To determine the prevalence of homosexuality among migrant oil workers in Niger Delta. Methods: A prospective questionnaire – based study was conducted among migrant oil workers in the Niger Delta region of Nigeria. The design was to determine the prevalence of homosexuality in the workers in oil workers.

  5. T gamma/delta lymphocytes in renal transplant recipients

    NARCIS (Netherlands)

    Raasveld, M. H.; Bloemena, E.; Surachno, S.; ten Berge, R. J.

    1992-01-01

    T gamma/delta lymphocytes are able to perform allospecific cytotoxicity and natural killer cytotoxicity in vitro. However, very little is known about their function in vivo. To investigate the possible involvement of T gamma/delta lymphocytes in the immune response to renal allografts, fine-needle

  6. The evolution of a subaqueous delta in the Anthropocene: A stratigraphic investigation of the Brazos River delta, TX USA

    Science.gov (United States)

    Carlin, Joseph A.; Dellapenna, Timothy M.

    2015-12-01

    Globally, deltas are increasingly threatened by anthropogenic activities. As a result, deltas now evolve through the combined effects of natural and human-induced processes occurring throughout the fluvial-deltaic system. The Brazos River delta, located along the Texas coast in the northwestern Gulf of Mexico, and its watershed have been impacted by direct and indirect human activities since the late 19th century. This provides an opportunity to investigate how such alterations have shaped the evolution of a delta in the Anthropocene, a time when humans are drivers of geological change. Historic alteration to the delta and watershed include extensive agricultural activity, jetty construction at the mouth in the late 1890s, mouth diversion ~10 km to the southwest in 1929, and reservoir construction throughout the early and mid 20th Century. Three subaerial deltaic geometries provided the framework to connect subaerial deltaic responses, to the anthropogenic alterations, to the resulting stratigraphic characteristics observed in the subaqueous delta. This study utilized high-resolution geophysical data (swath bathymetry, side scan sonar, CHIRP subbottom profiling) on the subaqueous delta to investigate the subaqueous delta stratigraphy and infer the processes that shaped the deltaic record over time. The results showed distinct areas across the subaqueous delta that were dominated by erosion and deposition. Erosional areas corresponded to earlier growth phase depocenters being exposed at the surface, while the depositional areas corresponded to areas with the most recent growth phase depocenter overlying the earlier depocenters. These results highlight that the subaqueous depocenter has migrated westward over time, consistent with the observed changes to the subaerial delta. Additionally, the data showed that evidence for these past growth phases and depocenters may be preserved within the subaqueous delta, even after subaerial portions of the delta returned to pre

  7. Losing ground in mega-deltas: basin-scale response to existential threats to the Mekong Delta

    Science.gov (United States)

    Arias, M. E.; Kondolf, G. M.; Schmitt, R. J. P.; Carling, P. A.; Darby, S. E.; Bizzi, S.; Castelletti, A.; Cochrane, T. A.; Gibson, S.; Kummu, M.; Oeurng, C.; Rubin, Z.; Wild, T. B.

    2017-12-01

    The Mekong Delta is, in terms of the number of livelihoods it supports, its economic importance, and in its vulnerability to climate change and sinking lands, one of the world's critically threatened mega-deltas. Livelihoods depend on the mere existence of the delta, but also on ecosystem services provided by the delta's drainage basin spanning 795,000 km2 in six abutting countries. These ecosystem services include delivery of sand required to build delta land in the face of rising sea-levels and sediment bound nutrients, provision of spawning habitat for fish that are ultimately harvested in the delta, and hydrologic regulation driving the delta's unique flood-pulse regime. However, while the delta is mainly located in Vietnam, the basin of the Mekong River is shared among China, Myanmar, Laos, Thailand, Cambodia, and Vietnam. In the context of the region's dynamic growth, individual countries are pushing their own development agendas, which include extensive dam building, in-channel sand mining, construction of dykes and canals, and groundwater pumping, all of which contribute to subsidence and erosion of the Delta. Our synthesis of recent research indicates that most of the Mekong's delta land will likely fall below sea-level by 2100 as result of these drivers, exacerbating the impacts of global climatic changes. In this context, local infrastructural projects and changes in land- and water-management may temporarily mitigate some negative effects, but do not address the existential threat to the delta as a whole. To prevent, or at least substantially postpone, the drowning of the Mekong Delta requires identification of the key drivers and immediate concerted management actions on the basin-scale to change the trajectory of subsidence and sediment deficit. A specific challenge is to find the institutional arrangements in this transnational context that could support the needed management changes and equitably distribute costs and impacts. The Mekong Delta is

  8. Deprivation and Resistance: Environmental Crisis, Political Action, and Conflict Resolution in the Niger Delta since the 1980s

    Directory of Open Access Journals (Sweden)

    David Aworawo

    2013-05-01

    Full Text Available The interlocking relationship between environmental degradation, poverty,and violent conflict has been a prominent theme contained within the literature on sustainable development and conflict resolution since the midtwentieth century. While some analysts have argued that violence has not been limited to the poor and deprived, many have concluded from various studies that the devastation of the environment, poverty, and conflict are inextricably intertwined. This article examines this theme by analyzing the pattern of violence and nature of conflict resolution in the oil-producing enclave of the Niger Delta in the past three decades. A report of the United Nations Environment Programme on parts of the Niger Delta published in August 2011 reveals that the area is one of the most intensely polluted in the world. The report confirms the conclusion of several other earlier reports on the Niger Delta, which state that activities relating to the exploitation of oil and gas have led to intense environmental pollution and extreme poverty and that those conditions have spawned violence. The article is exploratory and analytical. It draws from diverse sources, including government records and reports of intergovernmental and non-governmental organizations as well as oral information gathered by the author from fieldwork conducted across the Niger Delta between 2007 and 2012, to explore the nature of the Niger Delta crisis from the 1980s until the present. The article argues that environmental degradation is central to the Niger Delta crisis, as it has hampered rural economic activities and posed a threat to human security. The article concludes that the effective tackling of the environmental crisis in the Niger Delta would surely reduce poverty and violence in the area.

  9. Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux

    NARCIS (Netherlands)

    Vrins, Carlos L. J.; van der Velde, Astrid E.; van den Oever, Karin; Levels, Johannes H. M.; Huet, Stephane; Elferink, Ronald P. J. Oude; Kuipers, Folkert; Groen, Albert K.

    2009-01-01

    Peroxisome proliferator-activated receptor delta (PPAR delta) is involved in regulation of energy homeostasis. Activation of PPAR delta markedly increases fecal neutral sterol secretion, the last step in reverse cholesterol transport. This phenomenon can neither be explained by increased

  10. Measurement of delta-rays in ATLAS silicon sensors

    CERN Document Server

    The ATLAS collaboration

    2013-01-01

    In the inner detector of the ATLAS experiment at the LHC, $\\delta$-rays originating from particle interactions in the silicon sensors may cause additional hit channels. A method for identifying silicon hit clusters that are enlarged due to the emission of a $\\delta$-ray is presented. Using pp collision data the expectation is confirmed that the $\\delta$-ray production rate depends linearly on the path length of the particle in silicon, independently of layer radius and detector technology. The range of the $\\delta$-rays, which is a property of the material and should not depend on anything else, is indeed found to be constant as a function of detector layer, path length in silicon and momentum of the particle traversing the silicon. As a by-product of this analysis a method is proposed that could correct for the effect of these $\\delta$-rays, and this could be used to improve track reconstruction.

  11. (p,. pi. /sup -/) reaction and. delta. /sup + +/ components of nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Kisslinger, L S; Miller, G A [Carnegie-Mellon Univ., Pittsburgh, Pa. (USA). Dept. of Physics

    1975-12-08

    The use of the (p,..pi../sup -/) reaction as a probe to determine ..delta../sup + +/(1232) components of nuclear wave functions is examined within the framework of a model which treats baryon resonances on the same footing as nucleons. Nuclear structure properties which affect the ..delta..-probability are discussed. Estimates of cross sections, at several energies, are made for the ..delta../sup + +/ transfer contribution as well as for the competing processes: proton charge exchange (p,n) followed by an (n,..gamma../sup -/) reaction; emission of a ..pi../sup 0/ followed by pion charge exchange (..pi../sup -/,..pi../sup 0/). Even with ..delta..-probabilities as small as 0.0001 the ..delta..-transfer process can compete with ordinary background charge-exchange reactions.

  12. Oxygen Nonstoichiometry and Defect Chemistry Modeling of Ce0.8Pr0.2O2-delta

    OpenAIRE

    Chatzichristodoulou, Christodoulos; Hendriksen, Peter Vang

    2010-01-01

    The oxygen nonstoichiometry (delta) of Ce0.8Pr0.2O2−delta has been measured as a function of PO2 at temperatures between 600 and 900°C by coulometric titration and thermogravimetry. An ideal solution defect model, a regular solution model, and a defect association model, taking into account the association of reduced dopant species and oxygen vacancies, were unable to reproduce the experimental results. However, excellent agreement with the experimentally determined oxygen nonstoichiometry co...

  13. Spectral factorization using the delta operator

    DEFF Research Database (Denmark)

    Rostgaard, Morten; Poulsen, Niels Kjølstad; Ravn, Ole

    1994-01-01

    In recent years many papers have been published abouth the gamma-operator, mostly caused by the better numerical properties and the rapprochement between continuous and discrete time. A major problem within the LQG-design of a delta-based input-output relation has been how to spectral-factorize...... solution to the spectral factorization problem. The key idea is to use the gamma-operator resembled by its behavior to the differential operator....... in an efficient way. The discrete-time method of Kuccera will not be applied since numerical word-length characteristics will be poor for fast sampling rates. In this paper a new approach is considered. A new gamma-operator (Tustin operator) is introduced, in order to make an iterative and numerical stable...

  14. $\\delta N$ formalism from superpotential and holography

    CERN Document Server

    Garriga, Jaume; Vernizzi, Filippo

    2016-02-16

    We consider the superpotential formalism to describe the evolution of scalar fields during inflation, generalizing it to include the case with non-canonical kinetic terms. We provide a characterization of the attractor behaviour of the background evolution in terms of first and second slow-roll parameters (which need not be small). We find that the superpotential is useful in justifying the separate universe approximation from the gradient expansion, and also in computing the spectra of primordial perturbations around attractor solutions in the $\\delta N$ formalism. As an application, we consider a class of models where the background trajectories for the inflaton fields are derived from a product separable superpotential. In the perspective of the holographic inflation scenario, such models are dual to a deformed CFT boundary theory, with $D$ mutually uncorrelated deformation operators. We compute the bulk power spectra of primordial adiabatic and entropy cosmological perturbations, and show that the results...

  15. Head orientation prediction: delta quaternions versus quaternions.

    Science.gov (United States)

    Himberg, Henry; Motai, Yuichi

    2009-12-01

    Display lag in simulation environments with helmet-mounted displays causes a loss of immersion that degrades the value of virtual/augmented reality training simulators. Simulators use predictive tracking to compensate for display lag, preparing display updates based on the anticipated head motion. This paper proposes a new method for predicting head orientation using a delta quaternion (DQ)-based extended Kalman filter (EKF) and compares the performance to a quaternion EKF. The proposed framework operates on the change in quaternion between consecutive data frames (the DQ), which avoids the heavy computational burden of the quaternion motion equation. Head velocity is estimated from the DQ by an EKF and then used to predict future head orientation. We have tested the new framework with captured head motion data and compared it with the computationally expensive quaternion filter. Experimental results indicate that the proposed DQ method provides the accuracy of the quaternion method without the heavy computational burden.

  16. Human influence on the sedimentation in the delta of the river Kyroenjoki, western Finland

    International Nuclear Information System (INIS)

    Heikkilae, R.

    1999-01-01

    of the 1970s below the level of 1930s, due to the construction of water reservoirs. On the basis of the chemical analyses of the sediment surface the delta was divided into two parts according to the sedimentary conditions. In the inner part with acid river water dominating, the conditions were reducing. The Fe/Mn ratio of the sediment was high, and the heavy metal content usually low. In the outer part of the delta, where weakly basic brackish water dominates, the sedimentary conditions were mostly oxidizing. The Fe/Mn ratio was low, and the heavy metal content usually high in the accumulation areas. This is because the fine-grained allochthonous material, which has a high heavy metal content, flocculates and precipitates when it reaches the brackish water of the Gulf of Bothnia, and the salinity and pH get higher. Due to land uplift and accumulation of the sediment, which together are approximately 2 cm a year, the delta gradually moves towards the sea. The present-day shallow bays will be filled and the deeper ones are formed into lakes. (orig.)

  17. Dependence of {delta}E effect on internal stresses in nickel: Experimental results by laser interferometry

    Energy Technology Data Exchange (ETDEWEB)

    Chicharro, J.M. [Dept. de Mecanica Aplicada e Ingenieria de Proyectos, E.T.S.I. Industriales, Universidad de Castilla-La Mancha, Avd. Camilo Jose Cela s/n, 13071 Ciudad Real (Spain)]. E-mail: josemanuel.chicharro@uclm.es; Bayon, A. [Dept. de Fisica Aplicada a los Recursos Naturales, E.T.S.I. Minas, Universidad Politecnica de Madrid, c/Rios Rosas, 21, 28003 Madrid (Spain); Salazar, F. [Dept. de Fisica Aplicada a los Recursos Naturales, E.T.S.I. Minas, Universidad Politecnica de Madrid, c/Rios Rosas, 21, 28003 Madrid (Spain)

    2006-02-15

    The speckle heterodyne interferometry is applied to the study of the dependence of Young's modulus on both the magnetic field and the internal stresses in a soft ferromagnetic material. Young's modulus is determined from the first natural longitudinal frequency of a slender magnetic rod positioned within a solenoid. Vibration of the sample is detected by an optical heterodyne system with a wide bandwidth. The samples are heated to above the Curie point and then cooled at several rates in order to induce different internal stresses. The study refers to nickel rods 10mm in diameter and 110mm in length. The grain sizes of the samples are also determined and related to changes in {delta}E.

  18. Perspectives on bay-delta science and policy

    Science.gov (United States)

    Healey, Michael; Dettinger, Michael; Norgaard, Richard

    2016-01-01

    The State of Bay–Delta Science 2008 highlighted seven emerging perspectives on science and management of the Delta. These perspectives had important effects on policy and legislation concerning management of the Delta ecosystem and water exports. From the collection of papers that make up the State of Bay–Delta Science 2016, we derive another seven perspectives that augment those published in 2008. The new perspectives address nutrient and contaminant concentrations in Delta waters, the failure of the Delta food web to support native species, the role of multiple stressors in driving species toward extinction, and the emerging importance of extreme events in driving change in the ecosystem and the water supply. The scientific advances that underpin these new perspectives were made possible by new measurement and analytic tools. We briefly discuss some of these, including miniaturized acoustic fish tags, sensors for monitoring of water quality, analytic techniques for disaggregating complex contaminant mixtures, remote sensing to assess levee vulnerability, and multidimensional hydrodynamic modeling. Despite these new tools and scientific insights, species conservation objectives for the Delta are not being met. We believe that this lack of progress stems in part from the fact that science and policy do not incorporate sufficiently long-term perspectives. Looking forward half a century was central to the Delta Visioning process, but science and policy have not embraced this conceptual breadth. We are also concerned that protection and enhancement of the unique cultural, recreational, natural resource, and agricultural values of the Delta as an evolving place, as required by the Delta Reform Act, has received no critical study and analysis. Adopting wider and longer science and policy perspectives immediately encourages recognition of the need for evaluation, analysis, and public discourse on novel conservation approaches. These longer and wider perspectives

  19. The Atchafalaya River Delta. Report 7. Analytical Analysis of the Development of the Atchafalaya River Delta.

    Science.gov (United States)

    1985-09-01

    responsible for the abrupt increases in subaerial delta growth. 64. Through using satellite imagery, color infrared photog- raphy, and digital current...w RO CF = HO/A/BO/(2.-D) w (HH wo (2.-D) - 1.) + O.5/AA X2 = BO m 2.m AA a HHow(D-1.) o CF AREA = (2.wAAwB~ ww2 ) im (CKI*(1. + AmBO/HOwRO) ww2 &+ CK2 a

  20. Circuitous to single thread: post-dam geomorphic transformation of the Colorado River in its delta

    Science.gov (United States)

    Mueller, E. R.; Schmidt, J. C.

    2017-12-01

    The Colorado River in its delta has transformed from a maze of secondary and distributary channels to an intermittent or ephemeral stream largely disconnected from formerly active channels and floodplains. Periodic post-dam floods have demonstrated that channel migration and shifting during floods increased the extent and diversity of riparian vegetation, and suggested that restoration of fluvial processes that promote re-activation of these former channels may enhance ecosystem rehabilitation. But restoration efforts in the delta are complicated by the fact that the Colorado River has the largest reservoir size in relation to its mean annual flow of any large river in North America and most of its sediment supply is completely blocked in upstream reservoirs. As a result, small controlled floods intended to inundate formerly active channels and rejuvenate riparian vegetation must consider the new relationship between stream flow and the delta's transformed geomorphology. Post-dam channel change has been dominated by the abandonment of secondary and distributary channels, with 3 to 4 meters of bed incision in the upstream part of the delta that diminishes downstream. Initial bed incision of 2 to 3 meters occurred rapidly following completion of Hoover Dam in 1936, before further upstream water development reduced delta flows to near zero by the mid-1960s. The largest post-dam floods occurred in the 1980s, which resulted in 10s to 100s of meters of lateral migration, channel switching, and the reactivation of secondary channels and floodplains rarely inundated since dam completion. Smaller flow pulses in the 1990s and 2000s further incised the thalweg to its minimum elevation, resulting in a narrow single-thread channel inset within the multi-channel surface active during the 1980s. In 2014, an experimental pulse flow was released to the river channel with a peak discharge approximately 5% of the typical pre-dam flood peak. Topographic change was confined to the main

  1. NTS radiological assessment project: comparison of delta-surface interpolation with kriging for the Frenchman Lake region of area 5

    International Nuclear Information System (INIS)

    Foley, T.A. Jr.

    1981-08-01

    The primary objective of this report is to compare the results of delta surface interpolation with kriging on four large sets of radiological data sampled in the Frenchman Lake region at the Nevada Test Site. The results of kriging, described in Barnes, Giacomini, Reiman, and Elliott, are very similar to those using the delta surface interpolant. The other topic studied is in reducing the number of sample points and obtaining results similar to those using all of the data. The positive results here suggest that great savings of time and money can be made. Furthermore, the delta surface interpolant is viewed as a contour map and as a three dimensional surface. These graphical representations help in the analysis of the large sets of radiological data

  2. Heat transfer augmentation along the tube wall of a louvered fin heat exchanger using practical delta winglets

    Energy Technology Data Exchange (ETDEWEB)

    Lawson, Michael J.; Thole, Karen A. [Mechanical and Nuclear Engineering Department, The Pennsylvania State University, University Park, PA 16802 (United States)

    2008-05-15

    Delta winglets are known to induce the formation of streamwise vortices and increase heat transfer between a working fluid and the surface on which the winglets are placed. This study investigates the use of delta winglets to augment heat transfer on the tube surface of louvered fin heat exchangers. It is shown that delta winglets placed on louvered fins produce augmentations in heat transfer along the tube wall as high as 47% with a corresponding increase of 19% in pressure losses. Manufacturing constraints are considered in this study whereby piercings in the louvered fins resulting from stamping the winglets into the louvered fins are simulated. Comparisons of measured heat transfer coefficients with and without piercings indicate that piercings reduce average heat transfer augmentations, but significant increases still occur with respect to no winglets present. (author)

  3. IMPACTS OF WETLAND DEGRADATION IN NIGER DELTA NIGERIA AND ITS SIGNIFICANCE IN FLOOD CONTROL

    Directory of Open Access Journals (Sweden)

    Enwere Chidimma Loveline

    2015-08-01

    Full Text Available  Wetlands perform a wide variety of functions that include flood control, ground water recharge, shore line stabilization, storm protection and climate moderation. However, despite these huge wetland functions, it has witnessed poor appreciation and dreadful conditions. Niger Delta has witnessed constant coastal erosion and rising sea level, this has led to large portions of the landmass being eroded. This paper aims to review some environmental effects of flooding in the Niger Delta region of Nigeria to provide the desired knowledge of role that wetlands play in reducing flood impacts. However, having witnessed the flood, the experience opened my eyes to the environmental challenges facing Niger Delta with respect to Wetlands degradation, poor perception of wetland values and functions, poor environmental practices and non-implementation of environmental regulations. This memorable experience rekindled the desire and motivation to seek a solution to wetland degradation with the aim of recognizing significance of wetlands at the centre of achieving both livelihood and biodiversity improvements to address coastal flooding problem.The study therefore concludes that wetlands are very significant in flood control and thus the conservation and restoration of wetlands, should put in place measures to reduce wetland destruction.International Journal of EnvironmentVolume-4, Issue-3, June-August 2015Page: 177-184

  4. Design and Implementation of Decimation Filter for 13-bit Sigma-Delta ADC Based on FPGA

    Directory of Open Access Journals (Sweden)

    Khalid Khaleel Mohammed

    2016-10-01

    Full Text Available A 13 bit Sigma-Delta ADC for a signal band of 40K Hz is designed in MATLAB Simulink and then implemented using Xilinx system generator tool.  The first order Sigma-Delta modulator is designed to work at a signal band of 40 KHz at an oversampling ratio (OSR of 256 with a sampling frequency of 20.48 MHz. The proposed decimation filter design is consists of a second order Cascaded Integrator Comb filter (CIC followed by two finite impulse response (FIR filters. This architecture reduces the need for multiplication which is need very large area. This architecture implements a decimation ratio of 256 and allows a maximum resolution of 13  bits in the output of the filter. The decimation filter was designed  and  tested  in  Xilinx  system  generator  tool  which  reduces  the  design  cycle  by  directly generating efficient VHDL code. The results obtained show that the overall Sigma-Delta ADC is able to achieve an ENOB (Effective Number Of Bit of 13.71 bits and SNR of 84.3 dB

  5. Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid

    DEFF Research Database (Denmark)

    Conti, P; De Amici, M; Bräuner-Osborne, Hans

    2002-01-01

    The synthesis and pharmacology of two potential glutamic acid receptor ligands are described. Preparation of the bicyclic 3-hydroxy-delta2-isoxazoline-cyclopentane derivatives (+/-)-7 and (+/-)-8 was accomplished via 1,3-dipolar cycloaddition of bromonitrile oxide to suitably protected 1-amino......-cyclopent-3-enecarboxylic acids. Their structure was established using a combination of 1H NMR spectroscopy and molecular mechanics calculations carried out on the intermediate cycloadducts (+/-)-11 and (+/-)-12. Amino acid derivatives (+/-)-7 and (+/-)-8 were assayed at ionotropic and metabotropic glutamic...... acid receptor subtypes and their activity compared with that of trans-ACPD and cis-ACPD. The results show that the replacement of the omega-carboxylic group of the model compounds with the 3-hydroxy-delta2-isoxazoline moiety abolishes or reduces drastically the activity at the metabotropic glutamate...

  6. Phosphorus losses from agricultural watersheds in the Mississippi Delta.

    Science.gov (United States)

    Yuan, Yongping; Locke, Martin A; Bingner, Ronald L; Rebich, Richard A

    2013-01-30

    Phosphorus (P) loss from agricultural fields is of environmental concern because of its potential impact on water quality in streams and lakes. The Mississippi Delta has long been known for its fish productivity and recreational value, but high levels of P in fresh water can lead to algal blooms that have many detrimental effects on natural ecosystems. Algal blooms interfere with recreational and aesthetic water use. However, few studies have evaluated P losses from agricultural watersheds in the Mississippi Delta. To better understand the processes influencing P loss, rainfall, surface runoff, sediment, ortho-P (orthophosphate, PO(4)-P), and total P (TP) were measured (water years 1996-2000) for two subwatersheds (UL1 and UL2) of the Deep Hollow Lake Watershed and one subwatershed of the Beasley Lake Watershed (BL3) primarily in cotton production in the Mississippi Delta. Ortho-P concentrations ranged from 0.01 to 1.0 mg/L with a mean of 0.17 mg/L at UL1 (17.0 ha), 0.36 mg/L at UL2 (11.2 ha) and 0.12 mg/L at BL3 (7.2 ha). The TP concentrations ranged from 0.14 to 7.9 mg/L with a mean of 0.96 mg/L at UL1, 1.1 mg/L at UL2 and 1.29 mg/L at BL3. Among the three sites, UL1 and UL2 received P application in October 1998, and BL3 received P applications in the spring of 1998 and 1999. At UL1, ortho-P concentrations were 0.36, 0.25 and 0.16 for the first, second and third rainfall events after P application, respectively; At UL2, ortho-P concentrations were 1.0, 0.66 and 0.65 for the first, second and third rainfall events after P application, respectively; and at BL3, ortho-P concentrations were 0.11, 0.22 and 0.09 for the first, second and third rainfall events after P application, respectively. P fertilizer application did influence P losses, but high P concentrations observed in surface runoff were not always a direct result of P fertilizer application or high rainfall. Application of P in the fall (UL1 and UL2) resulted in more ortho-P losses, likely

  7. Primary production in the Delta: Then and now

    Science.gov (United States)

    Cloern, James E.; Robinson, April; Richey, Amy; Grenier, Letitia; Grossinger, Robin; Boyer, Katharyn E.; Burau, Jon; Canuel, Elizabeth A.; DeGeorge, John F.; Drexler, Judith Z.; Enright, Chris; Howe, Emily R.; Kneib, Ronald; Mueller-Solger, Anke; Naiman, Robert J.; Pinckney, James L.; Safran, Samuel M.; Schoellhamer, David H.; Simenstad, Charles A.

    2016-01-01

    To evaluate the role of restoration in the recovery of the Delta ecosystem, we need to have clear targets and performance measures that directly assess ecosystem function. Primary production is a crucial ecosystem process, which directly limits the quality and quantity of food available for secondary consumers such as invertebrates and fish. The Delta has a low rate of primary production, but it is unclear whether this was always the case. Recent analyses from the Historical Ecology Team and Delta Landscapes Project provide quantitative comparisons of the areal extent of 14 habitat types in the modern Delta versus the historical Delta (pre-1850). Here we describe an approach for using these metrics of land use change to: (1) produce the first quantitative estimates of how Delta primary production and the relative contributions from five different producer groups have been altered by large-scale drainage and conversion to agriculture; (2) convert these production estimates into a common currency so the contributions of each producer group reflect their food quality and efficiency of transfer to consumers; and (3) use simple models to discover how tidal exchange between marshes and open water influences primary production and its consumption. Application of this approach could inform Delta management in two ways. First, it would provide a quantitative estimate of how large-scale conversion to agriculture has altered the Delta's capacity to produce food for native biota. Second, it would provide restoration practitioners with a new approach—based on ecosystem function—to evaluate the success of restoration projects and gauge the trajectory of ecological recovery in the Delta region.

  8. How Rapid Change Affects Deltas in the Arctic Region

    Science.gov (United States)

    Overeem, I.; Bendixen, M.

    2017-12-01

    Deltas form where the river drains into the ocean. Consequently, delta depositional processes are impacted by either changes in the respective river drainage basin or by changes in the regional marine environment. In a warming Arctic region rapid change has occurred over the last few decades in both the terrestrial domain as well as in the marine domain. Important terrestrial controls include 1) change in permafrost possibly destabilizing river banks, 2) strong seasonality of river discharge due to a short melting season, 3) high sediment supply if basins are extensively glaciated, 4) lake outbursts and ice jams favoring river flooding. Whereas in the Arctic marine domain sea ice loss promotes wave and storm surge impact, and increased longshore transport. We here ask which of these factors dominate any morphological change in Arctic deltas. First, we analyze hydrological data to assess change in Arctic-wide river discharge characteristics and timing, and sea ice concentration data to map changes in sea ice regime. Based on this observational analysis we set up a number of scenarios of change. We then model hypothetical small-scale delta formation considering change in these primary controls by setting up a numerical delta model, and combining it dynamically with a permafrost model. We find that for typical Greenlandic deltas changes in river forcing due to ice sheet melt dominate the morphological change, which is corroborated by mapping of delta progradation from aerial photos and satellite imagery. Whereas in other areas, along the North Slope and the Canadian Arctic small deltas are more stable or experienced retreat. Our preliminary coupled model allows us to further disentangle the impact of major forcing factors on delta evolution in high-latitude systems.

  9. Hot deformation behavior of delta-processed superalloy 718

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y., E-mail: wangyanhit@yahoo.cn [State Key Laboratory of Powder Metallurgy, Central South University, Changsha 410083 (China); School of Aeronautics and Astronautics, Central South University, Changsha 410083 (China); Shao, W.Z.; Zhen, L.; Zhang, B.Y. [School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001 (China)

    2011-03-25

    Research highlights: {yields} The peak stress for hot deformation can be described by the Z parameter. {yields} The grain size of DRX was inversely proportional to the Z parameter. {yields} The dissolution of {delta} phases was greatly accelerated under hot deformation. {yields}The {delta} phase stimulated nucleation can serve as the main DRX mechanism. - Abstract: Flow stress behavior and microstructures during hot compression of delta-processed superalloy 718 at temperatures from 950 to 1100 deg. C with strain rates of 10{sup -3} to 1 s{sup -1} were investigated by optical microscopy (OM), electron backscatter diffraction (EBSD) technique and transmission electron microscopy (TEM). The relationship between the peak stress and the deformation conditions can be expressed by a hyperbolic-sine type equation. The activation energy for the delta-processed superalloy 718 is determined to be 467 kJ/mol. The change of the dominant deformation mechanisms leads to the decrease of stress exponent and the increase of activation energy with increasing temperature. The dynamically recrystallized grain size is inversely proportional to the Zener-Hollomon (Z) parameter. It is found that the dissolution rate of {delta} phases under hot deformation conditions is much faster than that under static conditions. Dislocation, vacancy and curvature play important roles in the dissolution of {delta} phases. The main nucleation mechanisms of dynamic recrystallization (DRX) for the delta-processed superalloy 718 include the bulging of original grain boundaries and the {delta} phase stimulated DRX nucleation, which is closely related to the dissolution behavior of {delta} phases under certain deformation conditions.

  10. Primary Production in the Delta: Then and Now

    Directory of Open Access Journals (Sweden)

    James E. Cloern

    2016-10-01

    Full Text Available doi: http://dx.doi.org/10.15447/sfews.2016v14iss3art1To evaluate the role of restoration in the recovery of the Delta ecosystem, we need to have clear targets and performance measures that directly assess ecosystem function. Primary production is a crucial ecosystem process, which directly limits the quality and quantity of food available for secondary consumers such as invertebrates and fish. The Delta has a low rate of primary production, but it is unclear whether this was always the case. Recent analyses from the Historical Ecology Team and Delta Landscapes Project provide quantitative comparisons of the areal extent of 14 habitat types in the modern Delta versus the historical Delta (pre-1850. Here we describe an approach for using these metrics of land use change to: (1 produce the first quantitative estimates of how Delta primary production and the relative contributions from five different producer groups have been altered by large-scale drainage and conversion to agriculture; (2 convert these production estimates into a common currency so the contributions of each producer group reflect their food quality and efficiency of transfer to consumers; and (3 use simple models to discover how tidal exchange between marshes and open water influences primary production and its consumption. Application of this approach could inform Delta management in two ways. First, it would provide a quantitative estimate of how large-scale conversion to agriculture has altered the Delta's capacity to produce food for native biota. Second, it would provide restoration practitioners with a new approach—based on ecosystem function—to evaluate the success of restoration projects and gauge the trajectory of ecological recovery in the Delta region.

  11. LIVER TRANSPLANTATION IN HEPATITIS DELTA: SOUTH AMERICA EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Daniel Souza LIMA

    Full Text Available ABSTRACT BACKGROUND: The Amazon region is one of the main endemic areas of hepatitis delta in the world and the only one related to the presence of genotype 3 of the delta virus. OBJECTIVE: To analyze the profile, mortality and survival of cirrhotic patients submitted to liver transplantation for chronic hepatitis delta virus and compare with those transplanted by hepatitis B virus monoinfection. METHODS: Retrospective, observational and descriptive study. From May 2002 to December 2011, 629 liver transplants were performed at the Walter Cantídio University Hospital, of which 29 patients were transplanted due to cirrhosis caused by chronic delta virus infection and 40 by hepatitis B chronic monoinfection. The variables analyzed were: age, sex, MELD score, Child-Pugh score, upper gastrointestinal bleeding and hepatocellular carcinoma occurrence before the transplantation, perioperative platelet count, mortality and survival. RESULTS: The Delta Group was younger and all came from the Brazilian Amazon Region. Group B presented a higher proportion of male patients (92.5% compared to Group D (58.6%. The occurrence of upper gastrointestinal bleeding before transplantation, MELD score, and Child-Pugh score did not show statistical differences between groups. The occurrence of hepatocellular carcinoma and mortality were higher in the hepatitis B Group. The survival in 4 years was 95% in the Delta Group and 75% in the B Group, with a statistically significant difference (P=0.034. Patients with hepatitis delta presented more evident thrombocytopenia in the pre-transplantation and in the immediate postoperative period. CONCLUSION: The hepatitis by delta virus patients who underwent liver transplantation were predominantly male, coming from the Brazilian Amazon region and with similar liver function to the hepatitis B virus patients. They had a lower incidence of hepatocellular carcinoma, more marked perioperative thrombocytopenia levels and frequent

  12. Geomorphic change and sediment transport during a small artificial flood in a transformed post-dam delta: The Colorado River delta, United States and Mexico

    Science.gov (United States)

    Mueller, Erich R.; Schmidt, John C.; Topping, David J.; Shafroth, Patrick B.; Rodríguez-Burgueño, Jesús Eliana; Ramírez-Hernández, Jorge; Grams, Paul E.

    2017-01-01

    The Colorado River delta is a dramatically transformed landscape. Major changes to river hydrology and morpho-dynamics began following completion of Hoover Dam in 1936. Today, the Colorado River has an intermittent and/or ephemeral channel in much of its former delta. Initial incision of the river channel in the upstream ∼50 km of the delta occurred in the early 1940s in response to spillway releases from Hoover Dam under conditions of drastically reduced sediment supply. A period of relative quiescence followed, until the filling of upstream reservoirs precipitated a resurgence of flows to the delta in the 1980s and 1990s. Flow releases during extreme upper basin snowmelt in the 1980s, flood flows from the Gila River basin in 1993, and a series of ever-decreasing peak flows in the late 1990s and early 2000s further incised the upstream channel and caused considerable channel migration throughout the river corridor. These variable magnitude post-dam floods shaped the modern river geomorphology. In 2014, an experimental pulse-flow release aimed at rejuvenating the riparian ecosystem and understanding hydrologic dynamics flowed more than 100 km through the length of the delta’s river corridor. This small artificial flood caused localized meter-scale scour and fill of the streambed, but did not cause further incision or significant bank erosion because of its small magnitude. Suspended-sand-transport rates were initially relatively high immediately downstream from the Morelos Dam release point, but decreasing discharge from infiltration losses combined with channel widening downstream caused a rapid downstream reduction in suspended-sand-transport rates. A zone of enhanced transport occurred downstream from the southern U.S.-Mexico border where gradient increased, but effectively no geomorphic change occurred beyond a point 65 km downstream from Morelos Dam. Thus, while the pulse flow connected with the modern estuary, deltaic sedimentary processes were not

  13. Late quaternary evolution of the Orinoco Delta, Venezuela

    Science.gov (United States)

    Warne, A.G.; Guevara, E.H.; Aslan, A.

    2002-01-01

    The modern Orinoco Delta is the latest of a series of stacked deltas that have infilled the Eastern Venezuelan Basin (EVB) since the Oligocene. During the late Pleistocene sea-level lowstand (20,000 to 16,000 yrs BP), bedrock control points at the position of the present delta apex prevented the river channel from incising as deeply as many other major river systems. Shallow seismic data indicate that the late Pleistocene Orinoco incised into the present continental shelf, where it formed a braided-river complex that transported sediment to a series of shelf-edge deltas. As sea level rose from 16,000 to 9,500 yrs BP, the Orinoco shoreline shifted rapidly landward, causing shallow-marine waves and currents to form a widespread transgressive sand unit. Decelerating sea-level rise and a warmer, wetter climate during the early Holocene (9,500 to 6,000 yrs BP) induced delta development within the relatively quiet-water environment of the EVB embayment. Sea level approached its present stand in the middle Holocene (6,000 to 3,000 yrs BP), and the Orinoco coast prograded, broadening the delta plain and infilling the EVB embayment. Significant quantities of Amazon sediment began to be transported to the Orinoco coast by littoral currents. Continued progradation in the late Holocene caused the constriction at Boca de Serpientes to alter nearshore and shelf hydrodynamics and subdivide the submarine delta into two distinct areas: the Atlantic shelf and the Gulf of Paria. The increased influence of littoral currents along the coast promoted mudcape development. Because most of the water and sediment were transported across the delta plain through the Rio Grande distributary in the southern delta, much of the central and northwestern delta plain became sediment starved, promoting widespread accumulation of peat deposits. Human impacts on the delta are mostly associated with the Volca??n Dam on Can??o Manamo. However, human activities have had relatively little effect on the

  14. Is there a self-organization principle of river deltas?

    Science.gov (United States)

    Tejedor, Alejandro; Longjas, Anthony; Foufoula-Georgiou, Efi

    2017-04-01

    River deltas are known to possess a complex topological and flux-partitioning structure which has recently been quantified using spectral graph theory [Tejedor et al., 2015a,b]. By analysis of real and simulated deltas it has also been shown that there is promise in formalizing relationships between this topo-dynamic delta structure and the underlying delta forming processes [e.g., Tejedor et al., 2016]. The question we pose here is whether there exists a first order organizational principle behind the self-organization of river deltas and whether this principle can be unraveled from the co-evolving topo-dynamic structure encoded in the delta planform. To answer this question, we introduce a new metric, the nonlocal Entropy Rate (nER) that captures the information content of a delta network in terms of the degree of uncertainty in delivering fluxes from any point of the network to the shoreline. We hypothesize that if the "guiding principle" of undisturbed deltas is to efficiently and robustly build land by increasing the diversity of their flux pathways over the delta plane, then they would exhibit maximum nonlocal Entropy Rate at states at which geometry and flux dynamics are at equilibrium. At the same time, their nER would be non-optimal at transient states, such as before and after major avulsions during which topology and dynamics adjust to each other to reach a new equilibrium state. We will present our results for field and simulated deltas, which confirm this hypothesis and open up new ways of thinking about self-organization, complexity and robustness in river deltas. One particular connection of interest might have important implications since entropy rate and resilience are related by the fluctuation theorem [Demetrius and Manke, 2005], and therefore our results suggest that deltas might in fact self-organize to maximize their resilience to structural and dynamic perturbations. References: Tejedor, A., A. Longjas, I. Zaliapin, and E. Foufoula

  15. Holocene evolution of the western Orinoco Delta, Venezuela

    Science.gov (United States)

    Aslan, A.; White, W.A.; Warne, A.G.; Guevara, E.H.

    2003-01-01

    The pristine nature of the Orinoco Delta of eastern Venezuela provides unique opportunities to study the geologic processes and environments of a major tropical delta. Remote-sensing images, shallow cores, and radiocarbon-dating of organic remains form the basis for describing deltaic environments and interpreting the Holocene history of the delta. The Orinoco Delta can be subdivided into two major sectors. The southeast sector is dominated by the Rio Grande-the principal distributary-and complex networks of anastomosing fluvial and tidal channels. The abundance of siliciclastic deposits suggests that fluvial processes such as over-bank flooding strongly influence this part of the delta. In contrast, the northwest sector is represented by few major distributaries, and overbank sedimentation is less widespread relative to the southeast sector. Peat is abundant and occurs in herbaceous and forested swamps that are individually up to 200 km2 in area. Northwest-directed littoral currents transport large volumes of suspended sediment and produce prominent mudcapes along the northwest coast. Mapping of surface sediments, vegetation, and major landforms identified four principal geomorphic systems within the western delta plain: (1) distributary channels, (2) interdistributary flood basins, (3) fluvial-marine transitional environments, and (4) marine-influenced coastal environments. Coring and radiocarbon dating of deltaic deposits show that the northern delta shoreline has prograded 20-30 km during the late Holocene sea-level highstand. Progradation has been accomplished by a combination of distributary avulsion and mudcape progradation. This style of deltaic progradation differs markedly from other deltas such as the Mississippi where distributary avulsion leads to coastal land loss, rather than shoreline progradation. The key difference is that the Orinoco Delta coastal zone receives prodigious amounts of sediment from northwest-moving littoral currents that transport

  16. GRK2 Constitutively Governs Peripheral Delta Opioid Receptor Activity

    Directory of Open Access Journals (Sweden)

    Allison Doyle Brackley

    2016-09-01

    Full Text Available Opioids remain the standard for analgesic care; however, adverse effects of systemic treatments contraindicate long-term administration. While most clinical opioids target mu opioid receptors (MOR, those that target the delta class (DOR also demonstrate analgesic efficacy. Furthermore, peripherally restrictive opioids represent an attractive direction for analgesia. However, opioid receptors including DOR are analgesically incompetent in the absence of inflammation. Here, we report that G protein-coupled receptor kinase 2 (GRK2 naively associates with plasma membrane DOR in peripheral sensory neurons to inhibit analgesic agonist efficacy. This interaction prevents optimal Gβ subunit association with the receptor, thereby reducing DOR activity. Importantly, bradykinin stimulates GRK2 movement away from DOR and onto Raf kinase inhibitory protein (RKIP. protein kinase C (PKC-dependent RKIP phosphorylation induces GRK2 sequestration, restoring DOR functionality in sensory neurons. Together, these results expand the known function of GRK2, identifying a non-internalizing role to maintain peripheral DOR in an analgesically incompetent state.

  17. A High Performance Delta-Sigma Modulator for Neurosensing.

    Science.gov (United States)

    Xu, Jian; Zhao, Menglian; Wu, Xiaobo; Islam, Md Kafiul; Yang, Zhi

    2015-08-07

    Recorded neural data are frequently corrupted by large amplitude artifacts that are triggered by a variety of sources, such as subject movements, organ motions, electromagnetic interferences and discharges at the electrode surface. To prevent the system from saturating and the electronics from malfunctioning due to these large artifacts, a wide dynamic range for data acquisition is demanded, which is quite challenging to achieve and would require excessive circuit area and power for implementation. In this paper, we present a high performance Delta-Sigma modulator along with several design techniques and enabling blocks to reduce circuit area and power. The modulator was fabricated in a 0.18-µm CMOS process. Powered by a 1.0-V supply, the chip can achieve an 85-dB peak signal-to-noise-and-distortion ratio (SNDR) and an 87-dB dynamic range when integrated over a 10-kHz bandwidth. The total power consumption of the modulator is 13 µW, which corresponds to a figure-of-merit (FOM) of 45 fJ/conversion step. These competitive circuit specifications make this design a good candidate for building high precision neurosensors.

  18. The DELTA 181 lithium thionyl chloride battery

    Science.gov (United States)

    Sullivan, Ralph M.; Brown, Lawrence E.; Leigh, A. P.

    In 1986, the Johns Hopkins University/Applied Physics Laboratory (JHU/APL) undertook the development of a sensor module for the DELTA 181 spacecraft, a low earth orbit (LEO) mission of less than two months duration. A large lithium thionyl chloride battery was developed as the spacecraft's primary power source, the first known such use for this technology. The exceptionally high energy density of the lithium thionyl chloride cell was the primary driver for its use, resulting in a completed battery with a specific energy density of 120 Wh/lb. Safety requirements became the primary driver shaping all aspects of the power system design and development due to concerns about the potential hazards of this relatively new, high-energy technology. However, the program was completed without incident. The spacecraft was launched on February 8, 1988, from Kennedy Space Center (KSC) with over 60,000 Wh of battery energy. It reentered on April 2, 1988, still operating after 55 days, providing a successful, practical, and visible demonstration of the use of this technology for spacecraft applications.

  19. Chiral model for nucleon and delta

    International Nuclear Information System (INIS)

    Birse, M.C.; Banerjee, M.K.

    1985-01-01

    We propose a model of the nucleon and delta based on the idea that strong QCD forces on length scales approx.0.2--1 fm result in hidden chiral SU(2) x SU(2) symmetry and that there is a separation of roles between these forces which are also responsible for binding quarks in hadrons and the forces which produce absolute confinement. This leads us to study a linear sigma model describing the interactions of quarks, sigma mesons, and pions. We have solved this model in the semiclassical (mean-field) approximation for the hedgehog baryon state. We refer to this solution as a chiral soliton. In the semiclassical approximation the hedgehog state is a linear combination of N and Δ. We project this state onto states of good spin and isospin to calculate matrix elements of various operators in these states. Our results are in reasonable agreement with the observed properties of the nucleon. The mesonic contributions to g/sub A/ and sigma(πN) are about two to three times too large, suggesting the need for quantum corrections

  20. Delta Morphodynamics Matters! Ecosystem Services, Poverty and Morphodynamic Change in the Ganges-Brahmaputra Mega-Delta

    Science.gov (United States)

    Nicholls, R. J.; Adger, N.; Allan, A.; Darby, S. E.; Hutton, C.; Matthews, Z.; Rahman, M.; Whitehead, P. G.; Wolf, J.

    2013-12-01

    The world's deltas are probably the most vulnerable type of coastal environment, and they face multiple stresses in the coming decades. These stresses include, amongst others, local drivers due to land subsidence, population growth and urbanisation within the deltas, regional drivers due to changes in catchment management (e.g. upstream land use and dam construction), as well as global climate change impacts such as sea-level rise. At the same time, the ecosystem services of river deltas support high population densities, with around 14% of the global population inhabiting deltas. A large proportion of these people experience extremes of poverty and they are therefore severely exposed to vulnerability from environmental and ecological stress and degradation. In areas close to or below the poverty boundary, both subsistence and cash elements of the economy tend to rely disproportionately heavily on ecosystem services which underpin livelihoods. Therefore, to sustainably manage delta environments they must be viewed as complex social-environmental systems where change is only partially driven by physical drivers such as sea level rise and climate change, and human-induced development activities are also critical. Here we outline a new conceptual framework for the development of methods to understand and characterise the key drivers of change in ecosystem services that affect the environment and economic status of populous deltas, focusing specifically on the Ganges-Brahmaputra-Meghna (GBM) mega-delta. The GBM delta is characterised by densely populated coastal lowlands with significant poverty, with livelihoods supported to a large extent by natural ecosystems such as the Sunderbahns (the largest mangrove forest in the world). However, the GBM delta is under severe development pressure due to many growing cities. At present the importance of ecosystems services to poverty and livelihoods is poorly understood. This is due to due to the complexity of interactions

  1. The situation in the Niger Delta; La situation dans le delta du Niger

    Energy Technology Data Exchange (ETDEWEB)

    Vitalis, E

    2007-07-15

    An energy issue for the United States and a political challenge for Europe, Nigeria is experiencing growing instability and is on the verge of civil war; the ecosystem and the population of the Niger Delta are the main victims. The State, corrupt, is powerless to contain the rising violence and redistribute the proceeds of oil sales. It is high time for oil-consuming countries, starting with the United States, to concern themselves with stabilizing the region. Europe must contribute to the lasting development of this country. (author)

  2. The Niger Delta Avengers, Autonomous Ethnic Clans and Common ...

    African Journals Online (AJOL)

    Nneka Umera-Okeke

    therefore investigated the sudden emergence of Niger Delta Avengers ... hardship, deprivations and environmental degradation occasioned by oil pipeline .... analysis of coded materials of the library such as books, magazines, journals,.

  3. Rarotonga Radiocarbon (delta 14C) for 1950 to 1997

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Rarotonga coral radiocarbon (14C) timeseries. Coral radiocarbon (Delta-14C) on untreated, low-speed drilled samples. Precision is +/- 4 per mil as documented by an...

  4. Novel urinary metabolite of d-delta-tocopherol in rats

    International Nuclear Information System (INIS)

    Chiku, S.; Hamamura, K.; Nakamura, T.

    1984-01-01

    A novel metabolite of d-delta-tocopherol was isolated from the urine of rats given d-3,4-[ 3 H 2 ]-delta-tocopherol intravenously. The metabolite was collected from the urine of rats given d-delta-tocopherol in the same manner as that of the labeled compound. It was found that the metabolites consisted of sulfate conjugates. The portion of the major metabolite released with sulfatase was determined to be 2,8-dimethyl-2-(2'-carboxyethyl)-6-chromanol by infrared spectra, nuclear magnetic resonance spectra, and mass spectra. The proposed structure was confirmed by comparing the analytical results with those of a synthetically derived compound. As a result of the structural elucidation of this novel metabolite, a pathway for the biological transformation of delta-tocopherol is proposed which is different from that of alpha-tocopherol. A characteristic feature of the pathway is the absence of any opening of the chroman ring throughout the sequence

  5. Environmental Law and Underdevelopment in the Niger Delta ...

    African Journals Online (AJOL)

    Environmental Law and Underdevelopment in the Niger Delta Region of Nigeria. ... is composed of many ecosystems of great economic and social importance, ... producing companies contribute to the degradation of the environment which in ...

  6. Delta-ray spectroscopy of quasi-atoms

    International Nuclear Information System (INIS)

    Kozhuharov, C.

    1983-01-01

    The spectroscopy of high energy delta-rays, emitted in collisions of very heavy ions, is studied. The ''orange''-type beta-spectrometer and the achromatic electron channel are the experimental setups. Delta ray production probabilities are studied as a function of the distance of closest approach R /SUB min/ or the impact parameter b. Coulomb ionization, ion trajectory, scaling laws, double differential cross sections, and K-X-rays information is extracted from the experiment. The dependence of delta-ray emission on the united charge number Z /SUB u/ is discussed. Asymmetric collision systems with Z x alpha approx. = 1 (delta ray spectrum from Pb→Sn collisions) are studied. Finally, very heavy collisions, such as 208 Pb + 208 Pb collisions at bombarding energy fas below the Coulomb barrier are touched upon

  7. precise delta extraction scheme for reprogramming of wireless

    African Journals Online (AJOL)

    eobe

    Keywords- reprogramming; operating system, wireless sensor network, Delta. 1. INTRODUCTION ... It entails the transmission of only modified modules that are then ... higher power consumption and slow system execution are drawbacks ...

  8. Pattern of Complicated Unsafe Abortions in Niger Delta University ...

    African Journals Online (AJOL)

    Alasia Datonye

    of cases of complicated unsafe abortion managed at the. Niger Delta University ... previous termination of pregnancy and 87.3% of the patients had ... and outcome were obtained. ... life-threatening complications, post- abortion family planning.

  9. DEltas, vulnerability and Climate Change: Migration and Adaptation ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Hutton C.W.

    Stakeholder Dialogue, London, June 19th, 2014. DEltas, vulnerability and Climate. Change: Migration and Adaptation. (DECCMA). Stakeholder Dialogue. Radisson Blu Edwardian Grafton Hotel, London, UK. June 19th, 2014 ...

  10. Ecohealth Approach to Flood Recession Farming in Okavango Delta ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    In the Okavango Delta, Botswana, flood-recession farming (molapu) is a lucrative but ... Moreover, some practices involved in molapu farming may pose a threat to the ... Linking research to urban planning at the ICLEI World Congress 2018.

  11. What are Pregnant Women in a Rural Niger Delta Community's ...

    African Journals Online (AJOL)

    Erah

    Buchanan House, Glasgow Caledonian University Email: Caroline. ... exploratory qualitative study was carried out to identify pregnant women in a rural Niger Delta community's perceptions of ..... sometimes you stay for the whole day.

  12. Nucleon and delta masses in twisted mass chiral perturbation theory

    International Nuclear Information System (INIS)

    Walker-Loud, Andre; Wu, Jackson M.S.

    2005-01-01

    We calculate the masses of the nucleons and deltas in twisted mass heavy baryon chiral perturbation theory. We work to quadratic order in a power counting scheme in which we treat the lattice spacing, a, and the quark masses, m q , to be of the same order. We give expressions for the mass and the mass splitting of the nucleons and deltas both in and away from the isospin limit. We give an argument using the chiral Lagrangian treatment that, in the strong isospin limit, the nucleons remain degenerate and the delta multiplet breaks into two degenerate pairs to all orders in chiral perturbation theory. We show that the mass splitting between the degenerate pairs of the deltas first appears at quadratic order in the lattice spacing. We discuss the subtleties in the effective chiral theory that arise from the inclusion of isospin breaking

  13. Restoration of Delta Streams: A Case History and Conceptual Model

    National Research Council Canada - National Science Library

    Killgore, K. J; Hoover, Jan J; Murphy, Catherine E; Parrish, Kent D; Johnson, David R; Myers, Karen F

    2008-01-01

    .... Low water, excessive sedimentation in smaller delta streams, and the accumulation of pesticides such as DDT are the consequences of these anthropogenic disturbances resulting in dominance of tolerant fish species...

  14. LiDAR data for the Delta Area of California

    Data.gov (United States)

    California Natural Resource Agency — LiDAR data for the Delta Area of California from the California Department of Water Resources. Bare earth grids from LiDAR.This data is in ESRI Grid format with 2...

  15. Disparate effects of p24alpha and p24delta on secretory protein transport and processing.

    Directory of Open Access Journals (Sweden)

    Jeroen R P M Strating

    Full Text Available BACKGROUND: The p24 family is thought to be somehow involved in endoplasmic reticulum (ER-to-Golgi protein transport. A subset of the p24 proteins (p24alpha(3, -beta(1, -gamma(3 and -delta(2 is upregulated when Xenopus laevis intermediate pituitary melanotrope cells are physiologically activated to produce vast amounts of their major secretory cargo, the prohormone proopiomelanocortin (POMC. METHODOLOGY/PRINCIPAL FINDINGS: Here we find that transgene expression of p24alpha(3 or p24delta(2 specifically in the Xenopus melanotrope cells in both cases causes an effective displacement of the endogenous p24 proteins, resulting in severely distorted p24 systems and disparate melanotrope cell phenotypes. Transgene expression of p24alpha(3 greatly reduces POMC transport and leads to accumulation of the prohormone in large, ER-localized electron-dense structures, whereas p24delta(2-transgenesis does not influence the overall ultrastructure of the cells nor POMC transport and cleavage, but affects the Golgi-based processes of POMC glycomaturation and sulfation. CONCLUSIONS/SIGNIFICANCE: Transgenic expression of two distinct p24 family members has disparate effects on secretory pathway functioning, illustrating the specificity and non-redundancy of our transgenic approach. We conclude that members of the p24 family furnish subcompartments of the secretory pathway with specific sets of machinery cargo to provide the proper microenvironments for efficient and correct secretory protein transport and processing.

  16. Inequalities in Human Well-Being in the Urban Ganges Brahmaputra Meghna Delta

    Directory of Open Access Journals (Sweden)

    Sylvia Szabo

    2016-06-01

    Full Text Available The recently endorsed Sustainable Development Goals (SDGs agenda unanimously agrees on the need to focus on inclusive development, the importance of eradicating extreme poverty and managing often complex human well-being impacts of rapid urban growth. Sustainable and inclusive urbanisation will accelerate progress towards the SDGs and contribute to eradicating extreme poverty. In tropical delta regions, such as the Ganges Brahmaputra Meghna delta region, urban growth and resulting intra-urban inequalities are accelerated by the impact of environmental and climate change. In this context, the present study uses the 2010 Household Income and Expenditure Survey to analyse the extent of wealth-based inequalities in human well-being in the urban delta region and the determinants of selected welfare measures. The results suggest that the extent of intra-urban inequalities is greatest in educational attainment and access to postnatal healthcare and relatively low in the occurrence of gastric disease. The paper concludes by providing policy recommendations to reduce increasing wealth inequalities in urban areas, thus contributing to sustainable development of the region.

  17. Population decline in the Delta caribou herd with reference to other Alaskan herds

    Directory of Open Access Journals (Sweden)

    Patrick Valkenburg et al.

    1996-01-01

    Full Text Available After growing continuously for nearly 15 years, the Delta caribou herd began to decline in 1989. Most other Interior Alaskan herds also began declining. In the Delta herd, and in other herds, the declines were caused primarily by high summer mortality of calves and increased natural mortality of adult females. Other minor causes included increased winter mortality of calves, and reduced parturition rates of 3-year-old and older females. The decline in the Delta herd also coincided with increased wolf (Canis lupus numbers, winters with deeper than normal snow, and warm summers. Mean body weight of annual samples of 10-month-old female calves was consistently low during the decline. Except in some of the smallest Interior Alaskan herds, we conclude that evidence for population regulation in Alaskan caribou is weak, and that herds are likely to fluctuate within a wide range of densities due to complex interactions of predation and weather. Unless wolf numbers are influenced by man, the size of a caribou herd in a given year is likely to be largely a function of its size during the previous population low and the number of years of favorable weather in the interim.

  18. Low-sensitivity H ∞ filter design for linear delta operator systems with sampling time jitter

    Science.gov (United States)

    Guo, Xiang-Gui; Yang, Guang-Hong

    2012-04-01

    This article is concerned with the problem of designing H ∞ filters for a class of linear discrete-time systems with low-sensitivity to sampling time jitter via delta operator approach. Delta-domain model is used to avoid the inherent numerical ill-condition resulting from the use of the standard shift-domain model at high sampling rates. Based on projection lemma in combination with the descriptor system approach often used to solve problems related to delay, a novel bounded real lemma with three slack variables for delta operator systems is presented. A sensitivity approach based on this novel lemma is proposed to mitigate the effects of sampling time jitter on system performance. Then, the problem of designing a low-sensitivity filter can be reduced to a convex optimisation problem. An important consideration in the design of correlation filters is the optimal trade-off between the standard H ∞ criterion and the sensitivity of the transfer function with respect to sampling time jitter. Finally, a numerical example demonstrating the validity of the proposed design method is given.

  19. Sedimentation patterns in floodplains of the Mekong Delta - Vietnam

    Science.gov (United States)

    Van Manh, Nguyen; Merz, Bruno; Viet Dung, Nguyen; Apel, Heiko

    2013-04-01

    Quantification of floodplain sedimentation during the flood season in the Mekong Delta (MD) plays a very important role in the assessment of flood deposits for a sustainable agro-economic development. Recent studies on floodplain sedimentation in the region are restricted to small pilot sites because of the large extend of the Delta, and the complex channel. This research aims at a quantification of the sediment deposition in floodplains of the whole Mekong Delta, and to access the impacts of the upstream basin development on the sedimentation in the Delta quantitatively. To achieve this, a suspended sediment transport model is developed based on the quasi-2D hydrodynamic model of the whole Mekong Delta developed by Dung et al. (2011). The model is calibrated and validated using observed data derived from several sediment measurement campaigns in channel networks and floodplains. Measured sediment data and hydrodynamic model quantify the spatio-temporal variability of sediment depositions in different spatial units: individual dyke compartments, and the sub-regions Plain of Reeds, Long Xuyen Quadrangle and the area between Tien River and Hau River. It is shown that the distribution of sediment deposition over the delta is highly depended on the flood magnitude, that in turn drives the operation policy of flood control systems in floodplains of the Mekong Delta. Thus, the sedimentation distribution is influenced by the protection level of the dyke systems in place and the distance to the Tien River and Hau River, the main branches of the Mekong in the Delta. This corroborates the main findings derived from data analysis obtained from a small scale test site by Hung et al, (2011, 2012a). Moreover, the results obtained here underlines the importance of the main channels for the sediment transport into the floodplains, and the deposition rate in floodplains is strongly driven by the intake locations and the distance from these to the main channels as well.

  20. Studies of Louisiana's Deltas and Wetlands using SAR

    Science.gov (United States)

    Jones, C. E.

    2017-12-01

    Sustainable coastal environments exist in delicate balance between subsidence, erosion, and sea level rise on one hand and accretion of sediment and retention of decomposing organic matter on the other. In this talk we present results from a series of studies using an airborne L-band SAR (UAVSAR) to measure changing conditions in the Mississippi River Delta and coastal wetlands of Louisiana. Change within the Mississippi River delta (MRD), which is a highly engineered environment, is contrasted to those in the Wax Lake Delta, a small, naturally evolving delta located to the west of the current-day lobe of the MRD. The UAVSAR studies provide evidence that in the MRD subsidence and erosion related to human activities are increasing risk of flooding, submergence, and land loss. These are not seen in the Wax Lake Delta, where new land is forming. We evaluate geomorphic and hydrologic changes In the Wax Lake Delta and wetlands hydrologically connected to the Wax Lake Outlet canal that are apparent on the timescales of the UAVSAR data set, which consists of both near-yearly acquisitions (2009-2016) and several series of repeat acquisitions in 2015 and 2016 capturing conditions across a tidal cycle. Using the yearly data, we observe the evolution of subaqueous channels and crevasses in the delta and changes in distributary channels within the wetlands. We use water level change derived from InSAR applied to the rapid repeat data acquired during different stages of a tidal cycle to study the natural pattern of water flux within the delta and the coastal wetlands. The studies, results, and plans for future work will be presented. This work was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under contracts with the California Dept. of Water Resources and with the National Aeronautics and Space Administration.

  1. The Great Diversion: Danube Delta under Human Control (Invited)

    Science.gov (United States)

    Giosan, L.

    2009-12-01

    Many deltas around the world are suffering from sediment deficits that render them unstable to current and predicted rates of sea level rise. One solution proposed to alleviate the complete or partial drowning of such deltas is the use of river diversions to increase the quantity of sediment supplied to the delta plain to support marsh accretion. We examine the results of a half century old program of diversion in the Danube delta that led to the creation of an extensive diversion channel network akin in scope and size to a natural deltaic network. Danube’s importance as a shipping route increased after the Crimean War in the 1850s; the European Danube Commission was charged with maintaining the Sulina distributary as a shipping channel until 1940s. In the same period, several canals were dug to aid fishing in lakes and bring freshwater to brackish lagoons. After World War II, Communist authorities dramatically increased the number of canals for fishing, fish-farming and reed harvesting. New data on sedimentation rates and estimates of sediment fluxes suggest that the intensive canalization in the second half of the 20th Century led to increased sediment deposition that compensated the decreasing sediment discharge linked to damming within the internal fluvial part of the delta; however, the external marine delta has become increasingly sediment starved during the same interval. We emphasize the similarities and contrasts between the “human-controlled” and natural deltaic channel networks of the Danube delta and discuss the sustainability of the delta as a sediment budget problem within a sea level rise context.

  2. Governance of ‘long term delta planning’ in Bangladesh, Vietnam and the Netherlands

    NARCIS (Netherlands)

    Staveren, van M.F.

    2014-01-01

    The Deltas in Times of Climate Change Conference II, taking place in September 2014, Rotterdam, presented a suitable occasion to discuss both delta challenges and interesting approaches to how ‘delta dynamics’ are being dealt with worldwide.1 Delta dynamics include here both environmental (including

  3. Challenges and Approaches in River Delta Planning - Annexes to report on training workshop

    NARCIS (Netherlands)

    Wosten, J.H.M.; Douven, W.; Long Phi, H.; Fida Abdullah Khan, M.

    2012-01-01

    Programme, participants and all powerpoint presentations of the Delta Alliance Training Workshop: Challenges and approaches in river delta planning, sharing experiences from SE Asian Deltas and the Rhine-Meuse Delta. 22-26 October 2012, WACC, Vietnam National University, Ho Chi Minh City, Vietnam

  4. Natural levee evolution in the Rhine-Meuse delta, the Netherlands, during the first millennium CE

    NARCIS (Netherlands)

    Pierik, H.J.; Stouthamer, E.; Cohen, K.M.

    2017-01-01

    This paper presents reconstructions on natural levee development in the Rhine-Meuse delta, the Netherlands, during the first millennium CE, covering the full delta plain. It is the first study that performs this on a delta scale, which allows seeing the delta-wide trends on levee-forming controls

  5. Food and nutrition security trends and challenges in the Ganges Brahmaputra Meghna (GBM delta

    Directory of Open Access Journals (Sweden)

    Arnout van Soesbergen

    2017-09-01

    Full Text Available The population of the Ganges Brahmaputra Meghna (GBM delta is highly vulnerable to food insecurity and malnutrition due to the specific environmental, climatic and human development factors affecting agricultural production and fisheries. To better understand the impacts of climate and environmental change on food security and nutrition in this delta, this study combines spatially explicit data from the 2007 and 2011 Bangladesh Demographic and Health Survey (BDHS with a standard satellite remotely sensed vegetation greenness index (Normalised Difference Vegetation Index, NDVI, used as a proxy for rice production. The strength of association between NDVI and child nutrition in this tropical mega-delta were tested, showing correlations between two widely used indicators of child malnutrition; stunting and wasting, and deviations from a 10 year mean NDVI (anomalies for rice crop growing seasons – regarded as critical to individual children’s early lives. For children surveyed in 2007 we found that the likelihood of being stunted decreased with increased NDVI as a measure of food production. Similarly, for children surveyed in 2011, the likelihood of being wasted reduced with increased NDVI. However, regression results for stunting in 2011 and wasting in 2007 were not statistically significant. Our findings suggest that NDVI can be regarded as indicative of climatic variability and periods of low food production but is only partly successful as an indicator of climate related impacts on child nutrition in the GBM delta. Furthermore, our study highlights some of the uncertainties and challenges with linking environmental indicators such as the NDVI with household survey data across spatial and temporal scales.

  6. An integrated assessment framework for land subsidence in delta cities

    Directory of Open Access Journals (Sweden)

    T. H. M. Bucx

    2015-11-01

    Full Text Available In many delta cities land subsidence exceeds absolute sea level rise up to a factor of ten by excessive groundwater extraction related to rapid urbanization and population growth. Without change, parts of Jakarta, Ho Chi Minh City, Bangkok and numerous other delta (and coastal cities will sink below sea level. Increased flooding and also other widespread impacts of land subsidence result already in damage of billions of dollars per year. In order to gain insight in the complex, multi-sectoral aspects of subsidence, to raise awareness and to support decision making on appropriate adaptation strategies and measures, an Integrated Assessment Framework (IAF for subsidence is introduced, illustrated by several (delta case studies. Based on that a list of 10 generic key issues and possible solutions is presented in order to further develop and support a (generic approach how to deal with subsidence in current and future subsidence-prone areas. For exchange of experiences and knowledge development.on subsidence in deltas the Delta Alliance, a knowledge network of deltas worldwide, can be supportive.

  7. Sand transport, shear stress, and the building of a delta

    Science.gov (United States)

    Wagner, W.; Miller, K. L.; Hiatt, M. R.; Mohrig, D. C.

    2017-12-01

    River deltas distribute sediment to the coastal sea through a complex branching network of channels; however, the routing and storage of this sediment in and through the delta is poorly understood. We present results from field studies of the sediment and water transport through the branching Wax Lake Delta on the coast of Louisiana. Two channels studied, Main Pass and East Pass, maintain a near-equal total partitioning of flow and sediment. However, East Pass is narrower and has higher river velocities, lower tidal velocity fluctuations, less alluvial bed cover, and more sediment flux per unit width than Main Pass. We connect these differences to small differences in the geometry of the two channels and feedbacks between these differences. We link trends in measured sediment deposits to both measured and modeled shear velocities in Wax Lake Delta's channels and open water `islands' to understand how hydrologic processes shaped the sedimentary architecture of the delta. These connections define the sediment transport and deposition regimes in the WLD. We extend the results herein to suggest that the relationships between the available sediment and shear stress determines the basic planform of the Wax Lake Delta and cross-sectional geometries of its channels.

  8. The State of Bay–Delta Science 2016: An Introduction

    Directory of Open Access Journals (Sweden)

    Michael Healey

    2016-07-01

    Full Text Available doi: http://dx.doi.org/10.15447/sfews.2016v14iss2art5The State of Bay–Delta Science 2016 (SBDS is a collection of papers that summarizes the scientific understanding of the Sacramento–San Joaquin Delta, emphasizing progress made during the past decade.It builds on the first SBDS edition (Healey et al. 2008. Paper topics for this edition address the most relevant scientific issues in the Delta identified by senior scientists and managers. The topical papers cover issues ranging from contaminants in the Delta to levee stability, and from Delta food webs to recent discoveries about salmon migration. These papers are written for a scientific audience. Two additional papers, one describing the challenges of managing water and ecosystems in the Delta and another that discusses policy implications of the recent scientific findings, are written for a general audience. The papers will be published in at least two issues of San Francisco Estuary and Watershed Science and will be available as a set electronically.

  9. Metallicism and pulsation: an analysis of the delta Delphini stars

    International Nuclear Information System (INIS)

    Kurtz, D.W.

    1976-01-01

    Fine abundance analyses of seven delta Delphini stars and one delta Scuti star relative to four comparison standards are presented. Five of the delta Del stars are shown to have abundances most similar to the evolved Am stars. It is argued that these abundances are different from the classical Am star and Ap star abundances and that similarities to the Ba II star abundances are coincidental. We suggest that the anomalous abundance delta Del stars are evolved metallic line stars on the basis of their abundances, position in the β, M/sub v/ plane, inferred rotational velocities, and perhaps their binary incidence. Some of the delta Del stars are delta Scuti pulsators. We argue that pulsation and metallicism are mutually exclusive among the classical Am stars but may coexist in other stars related to the classical Am stars. A preference for the diffusion hypothesis model for the metallic line stars is stated and supported and the implications of the coexistence of pulsation and diffusion are discussed

  10. How yield relates to ash content, Delta 13C and Delta 18O in maize grown under different water regimes.

    Science.gov (United States)

    Cabrera-Bosquet, Llorenç; Sánchez, Ciro; Araus, José Luis

    2009-11-01

    Stable isotopes have proved a valuable phenotyping tool when breeding for yield potential and drought adaptation; however, the cost and technical skills involved in isotope analysis limit its large-scale application in breeding programmes. This is particularly so for Delta(18)O despite the potential relevance of this trait in C(4) crops. The accumulation of minerals (measured as ash content) has been proposed as an inexpensive way to evaluate drought adaptation and yield in C(3) cereals, but little is known of the usefulness of this measure in C(4) cereals such as maize (Zea mays). The present study investigates how yield relates to ash content, Delta(13)C and Delta(18)O, and evaluates the use of ash content as an alternative or complementary criterion to stable isotopes in assessing yield potential and drought resistance in maize. A set of tropical maize hybrids developed by CIMMYT were subjected to different water availabilities, in order to induce water stress during the reproductive stages under field conditions. Ash content and Delta(13)C were determined in leaves and kernels. In addition, Delta(18)O was measured in kernels. Water regime significantly affected yield, ash content and stable isotopes. The results revealed a close relationship between ash content in leaves and the traits informing about plant water status. Ash content in kernels appeared to reflect differences in sink-source balance. Genotypic variation in grain yield was mainly explained by the combination of ash content and Delta(18)O, whilst Delta(13)C did not explain a significant percentage of such variation. Ash content in leaves and kernels proved a useful alternative or complementary criterion to Delta(18)O in kernels for assessing yield performance in maize grown under drought conditions.

  11. Population dynamics, delta vulnerability and environmental change: comparison of the Mekong, Ganges–Brahmaputra and Amazon delta regions

    OpenAIRE

    Szabo, S.; Brondizio, E.; Renaud, F.G.; Hetrick, S.; Nicholls, R.; Matthews, Z.; Tessler, Z; Tejedor, A; Sebesvari, Z; Foufoula-Georgiou, E; da Costa, S; Dearing, J.A.

    2016-01-01

    Tropical delta regions are at risk of multiple threats including relative sea level rise and human alterations, making them more and more vulnerable to extreme floods, storms, surges, salinity intrusion, and other hazards which could also increase in magnitude and frequency with a changing climate. Given the environmental vulnerability of tropical deltas, understanding the interlinkages between population dynamics and environmental change in these regions is crucial for ensuring efficient pol...

  12. Mean proloculus size, delta super(13) C and delta super(18) O variations in recent benthic foraminifera from the west coast of India and their climatic implications

    Digital Repository Service at National Institute of Oceanography (India)

    Nigam, R.; Sarkar, A.

    The interrelationship between mean proloculus size (MPS), delta super(18) O and delta super(13) C vatiations in benthic foraminiferal species Rotalidium annectens and their relation with temperature (T) and salinity (S) have been studied in samples...

  13. Perspectives on Bay–Delta Science and Policy

    Directory of Open Access Journals (Sweden)

    Michael Healey

    2016-12-01

    Full Text Available doi: https://doi.org/10.15447/sfews.2016v14iss4art6The State of Bay–Delta Science 2008 highlighted seven emerging perspectives on science and management of the Delta. These perspectives had important effects on policy and legislation concerning management of the Delta ecosystem and water exports. From the collection of papers that make up the State of Bay–Delta Science 2016, we derive another seven perspectives that augment those published in 2008. The new perspectives address nutrient and contaminant concentrations in Delta waters, the failure of the Delta food web to support native species, the role of multiple stressors in driving species toward extinction, and the emerging importance of extreme events in driving change in the ecosystem and the water supply. The scientific advances that underpin these new perspectives were made possible by new measurement and analytic tools. We briefly discuss some of these, including miniaturized acoustic fish tags, sensors for monitoring of water quality, analytic techniques for disaggregating complex contaminant mixtures, remote sensing to assess levee vulnerability, and multidimensional hydrodynamic modeling. Despite these new tools and scientific insights, species conservation objectives for the Delta are not being met. We believe that this lack of progress stems in part from the fact that science and policy do not incorporate sufficiently long-term perspectives. Looking forward half a century was central to the Delta Visioning process, but science and policy have not embraced this conceptual breadth. We are also concerned that protection and enhancement of the unique cultural, recreational, natural resource, and agricultural values of the Delta as an evolving place, as required by the Delta Reform Act, has received no critical study and analysis. Adopting wider and longer science and policy perspectives immediately encourages recognition of the need for evaluation, analysis, and public discourse on

  14. Soil Organic Carbon Stocks in Arctic Deltaic Sediments: Investigations in the Lena River Delta.

    Science.gov (United States)

    Zubrzycki, S.; Kutzbach, L.; Desyatkin, A.; Pfeiffer, E.-M.

    2012-04-01

    -scaling over the soil-covered areas only, we excluded all water bodies from the geomorphological units studied (first river terrace and the active floodplains) and additionally corrected the extent of the first terrace's land area by reducing it by the percentage of small water ponds and cracks detected by high-resolution aerial photography for Samoylov Island. We scaled the area-weighted SSOC averages estimated for the two geomorphological units of Samoylov Island across the corrected total land areas of the Lena River Delta's first terrace (9,400 km2) and the active floodplains (3,500 km2) leading to total organic soil carbon storage estimates for a depth of 1 m of 290 Tg C and 50 Tg C, respectively.

  15. Lava delta deformation as a proxy for submarine slope instability

    Science.gov (United States)

    Di Traglia, Federico; Nolesini, Teresa; Solari, Lorenzo; Ciampalini, Andrea; Frodella, William; Steri, Damiano; Allotta, Benedetto; Rindi, Andrea; Marini, Lorenzo; Monni, Niccolò; Galardi, Emanuele; Casagli, Nicola

    2018-04-01

    The instability of lava deltas is a recurrent phenomenon affecting volcanic islands, which can potentially cause secondary events such as littoral explosions (due to interactions between hot lava and seawater) and tsunamis. It has been shown that Interferometric Synthetic Aperture Radar (InSAR) is a powerful technique to forecast the collapse of newly emplaced lava deltas. This work goes further, demonstrating that the monitoring of lava deltas is a successful strategy by which to observe the long-term deformation of subaerial-submarine landslide systems on unstable volcanic flanks. In this paper, displacement measurements derived from Synthetic Aperture Radar (SAR) imagery were used to detect lava delta instability at Stromboli volcano (Italy). Recent flank eruptions (2002-2003, 2007 and 2014) affected the Sciara del Fuoco (SdF) depression, created a "stacked" lava delta, which overlies a pre-existing scar produced by a submarine-subaerial tsunamigenic landslide that occurred on 30 December 2002. Space-borne X-band COSMO-SkyMED (CSK) and C-band SENTINEL-1A (SNT) SAR data collected between February 2010 and October 2016 were processed using the SqueeSAR algorithm. The obtained ground displacement maps revealed the differential ground motion of the lava delta in both CSK and SNT datasets, identifying a stable area (characterized by less than 2 mm/y in both datasets) within the northern sector of the SdF and an unstable area (characterized by velocity fields on the order of 30 mm/y and 160 mm/y in the CSK and SNT datasets, respectively) in the central sector of the SdF. The slope stability of the offshore part of the SdF, as reconstructed based on a recently performed multibeam bathymetric survey, was evaluated using a 3D Limit Equilibrium Method (LEM). In all the simulations, Factor of Safety (F) values between 0.9 and 1.1 always characterized the submarine slope between the coastline and -250 m a.s.l. The critical surfaces for all the search volumes corresponded to

  16. Initial isotopic geochemistry ({delta} 18 O, {delta} D) of fluids from wells of the Los Humeros, Pue., geothermal field; Geoquimica isotopica ({delta} 18 O, {delta} D) inicial de fluidos de pozos del campo geotermico de Los Humeros, Pue.

    Energy Technology Data Exchange (ETDEWEB)

    Barragan Reyes, Rosa Maria; Arellano Gomez, Victor Manuel [Instituto de Investigaciones Electricas, Gerencia de Geotermia, Cuernavaca, Morelos (Mexico)]. E-mail: rmb@iie.org.mx; Ramirez Montes, Miguel; Tovar Aguado, Rigoberto [Comision Federal de Electricidad, Gerencia de Proyectos Geotermoelectricos, Morelia, Michoacan (Mexico)

    2010-01-15

    Isotopic data ({delta} 18 O, {delta} D) from fluids from production wells at the Los Humeros, Pue., geothermal field were analyzed to investigate the possible origin of these fluids and the dominant processes of the reservoir at its initial state. According to pre-exploitation data, it is suggested the Los Humeros reservoir fluids are made of a mixture of meteoric water of very light isotopic composition (paleo-fluids) and andesitic water. The relationship {delta} D vs {delta} 18 O from pre-exploitation data indicates the produced fluids are composed of a mixture of (at least) two fluids with distinct isotopic compositions. At the more enriched end of the mixing relationship are the isotopic compositions of the wells H-23 and H-18 (located in the southern area of the field), while the lighter fluids were found in well H-16 (originally) and then in well H-16 (repaired). It was found that the liquid phases of deep wells are more enriched in {delta} 18 O while the shallow wells present lower values, suggesting a convection process at the initial state. Based on this isotopic profile, it is considered that even the production depths of the wells H-1, H-12 and H-16 (repaired) are just about the same, but their respective isotopic compositions are quite different. The {delta} 18 O value for well H-16 (repaired) seems to be that of condensate steam, while the corresponding values for wells H-1 and H-12 fall within the value interval of the deep wells (H-23). This suggests wells H-1 and H-12 are collecting very deep fluids enriched in {delta} 18 O. These results could be useful in creating a conceptual model of the reservoir. [Spanish] Se analizaron datos isotopicos ({delta}18 O, {delta}D) de los fluidos de pozos productores del campo geotermico de Los Humeros, Pue., para investigar el posible origen de los fluidos asi como los procesos dominantes del yacimiento en su estado inicial. De acuerdo con datos previos a la explotacion, se plantea que los fluidos del yacimiento

  17. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKC{delta} in cell culture and animal models of Parkinson's disease

    Energy Technology Data Exchange (ETDEWEB)

    Latchoumycandane, Calivarathan; Anantharam, Vellareddy; Jin, Huajun; Kanthasamy, Anumantha; Kanthasamy, Arthi, E-mail: arthik@iastate.edu

    2011-11-15

    The neurotoxicant 6-hydroxydopamine (6-OHDA) is used to investigate the cellular and molecular mechanisms underlying selective degeneration of dopaminergic neurons in Parkinson's disease (PD). Oxidative stress and caspase activation contribute to the 6-OHDA-induced apoptotic cell death of dopaminergic neurons. In the present study, we sought to systematically characterize the key downstream signaling molecule involved in 6-OHDA-induced dopaminergic degeneration in cell culture and animal models of PD. Treatment of mesencephalic dopaminergic neuronal N27 cells with 6-OHDA (100 {mu}M) for 24 h significantly reduced mitochondrial activity and increased cytosolic cytochrome c, followed by sequential activation of caspase-9 and caspase-3. Co-treatment with the free radical scavenger MnTBAP (10 {mu}M) significantly attenuated 6-OHDA-induced caspase activities. Interestingly, 6-OHDA induced proteolytic cleavage and activation of protein kinase C delta (PKC{delta}) was completely suppressed by treatment with a caspase-3-specific inhibitor, Z-DEVD-FMK (50 {mu}M). Furthermore, expression of caspase-3 cleavage site-resistant mutant PKC{delta}{sup D327A} and kinase dead PKC{delta}{sup K376R} or siRNA-mediated knockdown of PKC{delta} protected against 6-OHDA-induced neuronal cell death, suggesting that caspase-3-dependent PKC{delta} promotes oxidative stress-induced dopaminergic degeneration. Suppression of PKC{delta} expression by siRNA also effectively protected N27 cells from 6-OHDA-induced apoptotic cell death. PKC{delta} cleavage was also observed in the substantia nigra of 6-OHDA-injected C57 black mice but not in control animals. Viral-mediated delivery of PKC{delta}{sup D327A} protein protected against 6-OHDA-induced PKC{delta} activation in mouse substantia nigra. Collectively, these results strongly suggest that proteolytic activation of PKC{delta} is a key downstream event in dopaminergic degeneration, and these results may have important translational value for

  18. Flame propagation enhancement by plasma excitation of oxygen. Part II: Effects of O{sub 2}(a{sup 1}{delta}{sub g})

    Energy Technology Data Exchange (ETDEWEB)

    Ombrello, Timothy; Won, Sang Hee; Ju, Yiguang [Department of Mechanical and Aerospace Engineering, Engineering Quadrangle, Olden Street, Princeton, NJ 08544 (United States); Williams, Skip [Air Force Research Laboratory, Propulsion Directorate, 1950 Fifth Street, Wright-Patterson AFB, OH 45433 (United States)

    2010-10-15

    The isolated effect of O{sub 2}(a{sup 1}{delta}{sub g}) on the propagation of C{sub 2}H{sub 4} lifted flames was studied at reduced pressures (3.61 kPa and 6.73 kPa). The O{sub 2}(a{sup 1}{delta}{sub g}) was produced in a microwave discharge plasma and was isolated from O and O{sub 3} by NO addition to the plasma afterglow in a flow residence time on the order of 1 s. The concentrations of O{sub 2}(a{sup 1}{delta}{sub g}) and O{sub 3} were measured quantitatively through absorption by sensitive off-axis integrated-cavity-output spectroscopy and one-pass line-of-sight absorption, respectively. Under these conditions, it was found that O{sub 2}(a{sup 1}{delta}{sub g}) enhanced the propagation speed of C{sub 2}H{sub 4} lifted flames. Comparison with the results of enhancement by O{sub 3} found in part I of this investigation provided an estimation of 2-3% of flame speed enhancement for 5500 ppm of O{sub 2}(a{sup 1}{delta}{sub g}) addition from the plasma. Numerical simulation results using the current kinetic model of O{sub 2}(a{sup 1}{delta}{sub g}) over-predicts the flame propagation enhancement found in the experiments. However, the inclusion of collisional quenching rate estimations of O{sub 2}(a{sup 1}{delta}{sub g}) by C{sub 2}H{sub 4} mitigated the over-prediction. The present isolated experimental results of the enhancement of a hydrocarbon fueled flame by O{sub 2}(a{sup 1}{delta}{sub g}), along with kinetic modeling results suggest that further studies of C{sub n}H{sub m} + O{sub 2}(a{sup 1}{delta}{sub g}) collisional and reactive quenching are required in order to correctly predict combustion enhancement by O{sub 2}(a{sup 1}{delta}{sub g}). The present experimental results will have a direct impact on the development of elementary reaction rates with O{sub 2}(a{sup 1}{delta}{sub g}) at flame conditions to establish detailed plasma-flame kinetic mechanisms. (author)

  19. Event-rate and delta inflation when evaluating mortality as a primary outcome from randomized controlled trials of nutritional interventions during critical illness: a systematic review.

    Science.gov (United States)

    Summers, Matthew J; Chapple, Lee-anne S; McClave, Stephen A; Deane, Adam M

    2016-04-01

    There is a lack of high-quality evidence that proves that nutritional interventions during critical illness reduce mortality. We evaluated whether power calculations for randomized controlled trials (RCTs) of nutritional interventions that used mortality as the primary outcome were realistic, and whether overestimation was systematic in the studies identified to determine whether this was due to overestimates of event rate or delta. A systematic review of the literature between 2005 and 2015 was performed to identify RCTs of nutritional interventions administered to critically ill adults that had mortality as the primary outcome. Predicted event rate (predicted mortality during the control), predicted mortality during intervention, predicted delta (predicted difference between mortality during the control and intervention), actual event rate (observed mortality during control), observed mortality during intervention, and actual delta (difference between observed mortality during the control and intervention) were recorded. The event-rate gap (predicted event rate minus observed event rate), the delta gap (predicted delta minus observed delta), and the predicted number needed to treat were calculated. Data are shown as median (range). Fourteen articles were extracted, with power calculations provided for 10 studies. The predicted event rate was 29.9% (20.0–52.4%), and the predicted delta was 7.9% (3.0–20.0%). If the study hypothesis was proven correct then, on the basis of the power calculations, the number needed to treat would have been 12.7 (5.0–33.3) patients. The actual event rate was 25.3% (6.1–50.0%), the observed mortality during the intervention was 24.4% (6.3–39.7%), and the actual delta was 0.5% (−10.2–10.3%), such that the event-rate gap was 2.6% (−3.9–23.7%) and delta gap was 7.5% (3.2–25.2%). Overestimates of delta occur frequently in RCTs of nutritional interventions in the critically ill that are powered to determine a mortality

  20. Stratigraphy and paleohydrology of delta channel deposits, Jezero crater, Mars

    Science.gov (United States)

    Goudge, Timothy A.; Mohrig, David; Cardenas, Benjamin T.; Hughes, Cory M.; Fassett, Caleb I.

    2018-02-01

    The Jezero crater open-basin lake contains two well-exposed fluvial sedimentary deposits formed early in martian history. Here, we examine the geometry and architecture of the Jezero western delta fluvial stratigraphy using high-resolution orbital images and digital elevation models (DEMs). The goal of this analysis is to reconstruct the evolution of the delta and associated shoreline position. The delta outcrop contains three distinct classes of fluvial stratigraphy that we interpret, from oldest to youngest, as: (1) point bar strata deposited by repeated flood events in meandering channels; (2) inverted channel-filling deposits formed by avulsive distributary channels; and (3) a valley that incises the deposit. We use DEMs to quantify the geometry of the channel deposits and estimate flow depths of ∼7 m for the meandering channels and ∼2 m for the avulsive distributary channels. Using these estimates, we employ a novel approach for assessing paleohydrology of the formative channels in relative terms. This analysis indicates that the shift from meandering to avulsive distributary channels was associated with an approximately four-fold decrease in the water to sediment discharge ratio. We use observations of the fluvial stratigraphy and channel paleohydrology to propose a model for the evolution of the Jezero western delta. The delta stratigraphy records lake level rise and shoreline transgression associated with approximately continuous filling of the basin, followed by outlet breaching, and eventual erosion of the delta. Our results imply a martian surface environment during the period of delta formation that supplied sufficient surface runoff to fill the Jezero basin without major drops in lake level, but also with discrete flooding events at non-orbital (e.g., annual to decadal) timescales.

  1. Anadromous salmonids in the Delta: New science 2006–2016

    Science.gov (United States)

    Perry, Russell W.; Buchanan, Rebecca A.; Brandes, Patricia L.; Burau, Jon R.; Israel, Joshua A

    2016-01-01

    As juvenile salmon enter the Sacramento–SanJoaquin River Delta (“the Delta”) they disperse among its complex channel network where they are subject to channel-specific processes that affect their rate of migration, vulnerability to predation, feeding success, growth rates, and ultimately, survival. In the decades before 2006, tools available to quantify growth, dispersal, and survival of juvenile salmon in this complex channel network were limited.Fortunately, thanks to technological advances such as acoustic telemetry and chemical and structural otolith analysis, much has been learned over the past decade about the role of the Delta in the life cycle of juvenile salmon. Here, we review new science between 2006and 2016 that sheds light on how different life stages and runs of juvenile salmon grow, move, and survive in the complex channel network of the Delta. One of the most important advances during the past decade has been the widespread adoption of acoustic telemetry techniques. Use of telemetry has shed light on how survival varies among alternative migration routes and the proportion of fish that use each migration route. Chemical and structural analysis of otoliths has provided insights about when juveniles left their natal river and provided evidence of extended rearing in the brackish or saltwater regions of the Delta. New advancements in genetics now allow individuals captured by trawls to be assigned to specific runs. Detailed information about movement and survival in the Delta has spurred development of agent-based models of juvenile salmon that are coupled to hydrodynamic models. Although much has been learned, knowledge gaps remain about how very small juvenile salmon (fry and parr) use the Delta. Understanding how all life stages of juvenile salmon grow, rear, and survive in the Delta is critical for devising management strategies that support a diversity of life history strategies.

  2. Clinical applications of gamma delta T cells with multivalent immunity

    Directory of Open Access Journals (Sweden)

    Drew C Deniger

    2014-12-01

    Full Text Available Gamma delta T cells hold promise for adoptive immunotherapy because of their reactivity to bacteria, viruses, and tumors. However, these cells represent a small fraction (1-5% of the peripheral T-cell pool and require activation and propagation to achieve clinical benefit. Aminobisphosphonates specifically expand the Vgamma9Vdelta2 subset of gamma delta T cells and have been used in clinical trials of cancer where objective responses were detected. The Vgamma9Vdelta2 TCR heterodimer binds multiple ligands and results in a multivalent attack by a monoclonal T cell population. Alternatively, populations of gamma delta T cells with oligoclonal or polyclonal TCR repertoire could be infused for broad-range specificity. However, this goal has been restricted by a lack of applicable expansion protocols for non-Vgamma9Vdelta2 cells. Recent advances using immobilized antigens, agonistic monoclonal antibodies (mAbs, tumor-derived artificial antigen presenting cells (aAPC, or combinations of activating mAbs and aAPC have been successful in expanding gamma delta T cells with oligoclonal or polyclonal TCR repertoires. Immobilized MHC Class-I chain-related A was a stimulus for gamma delta T cells expressing TCRdelta1 isotypes, and plate-bound activating antibodies have expanded Vdelta1 and Vdelta2 cells ex vivo. Clinically-sufficient quantities of TCRdelta1, TCRdelta2, and TCRdelta1negTCRdelta2neg have been produced following co-culture on aAPC, and these subsets displayed differences in memory phenotype and reactivity to tumors in vitro and in vivo. Gamma delta T cells are also amenable to genetic modification as evidenced by introduction of alpha beta TCRs, chimeric antigen receptors (CARs, and drug-resistance genes. This represents a promising future for the clinical application of oligoclonal or polyclonal gamma delta T cells in autologous and allogeneic settings that builds on current trials testing the safety and efficacy of Vgamma9Vdelta2 T cells.

  3. A Delta Operator Approach for the Discrete-Time Active Disturbance Rejection Control on Induction Motors

    Directory of Open Access Journals (Sweden)

    John Cortés-Romero

    2013-01-01

    Full Text Available The problem of active disturbance rejection control of induction motors is tackled by means of a generalized PI observer based discrete-time control, using the delta operator approach as the methodology of analyzing the sampled time process. In this scheme, model uncertainties and external disturbances are included in a general additive disturbance input which is to be online estimated and subsequently rejected via the controller actions. The observer carries out the disturbance estimation, thus reducing the complexity of the controller design. The controller efficiency is tested via some experimental results, performing a trajectory tracking task under load variations.

  4. Challenges and Approaches in Delta Planning and Management - Sharing experiences from SE Asian Deltas and the Rhine-Meuse Delta -Report on Regional Training Workshop

    NARCIS (Netherlands)

    Long Phi, H.; Fida Abdullah Khan, M.; Wosten, J.H.M.; Douven, W.

    2014-01-01

    The training workshop consisted of a balanced mix of lectures on specific delta topics, work on group assignments, group and plenary discussions, and group presentations. Due to high professional level of the participants the discussions often reached the level of a policy dialogue among equals

  5. Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew.

    Science.gov (United States)

    Darmani, N A

    2001-01-01

    We have recently shown that the cannabinoid CB(1) receptor antagonist, SR 141716A, produces emesis in the least shrew (Cryptotis parva) in a dose- and route-dependent manner. This effect was blocked by delta-9-tetrahydrocannabinol (Delta(9)-THC). The present study investigates the cannabinoid receptor mechanisms by which Delta(9)-THC produces its antiemetic effects against cisplatin (20 mg/kg, i.p.)-induced emesis as well as its cannabimimetic activity profile (motor reduction) in the least shrew. Intraperitoneal administration of Delta(9)-THC (1, 2.5, 5 and 10 mg/kg) dose-dependently reduced both the percentage of animals vomiting (ID(50)=1.8+/-1.6 mg/kg) and the frequency of vomits (ID(50)=0.36+/-1.18 mg/kg) in a potent manner. The lowest significantly effective antiemetic dose of Delta(9)-THC for the latter emesis parameters was 2.5 mg/kg. Although Delta(9)-THC reduced the frequency of vomits up to 98%, it failed to completely protect all tested shrews from vomiting (80% protection). The cannabinoid CB(1) antagonist (SR 141716A) and not the CB(2) antagonist (SR 144528), reversed the antiemetic effects of Delta(9)-THC in a dose-dependent fashion. Delta(9)-THC (1, 5, 10 and 20 mg/kg, ip) suppressed locomotor parameters (spontaneous locomotor activity, duration of movement and rearing frequency) in a biphasic manner and only the 20-mg/kg dose simultaneously suppressed the triad of locomotor parameters to a significant degree. Subcutaneous (1-10 mg/kg) and intraperitoneal (0.05-40 mg/kg) injection of some doses of SR 141716A caused significant reductions in one or more components of the triad of locomotor parameters but these reductions were not dose dependent. Subcutaneous injection of SR 141716A (0.2, 1, 5 and 10 mg/kg) reversed the motor suppressant effects of a 20-mg/kg dose of Delta(9)-THC (ip) in a dose-dependent manner. Relative to its motor suppressant effects, Delta(9)-THC is a more potent antiemetic agent. Both effects are probably mediated via CB(1

  6. Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity

    DEFF Research Database (Denmark)

    Sabatakos, George; Rowe, Glenn C; Kveiborg, Marie

    2008-01-01

    DeltaFosB and a further truncated isoform (Delta2DeltaFosB) that lacks known transactivation domains but, like DeltaFosB, induces increased expression of osteoblast marker genes. MATERIALS AND METHODS: To test Delta2DeltaFosB's ability to induce bone formation in vivo, we generated transgenic mice......6 expression. CONCLUSIONS: DeltaFosB's AP-1 transactivating function is not needed to induce increased bone formation, and Delta2DeltaFosB may act, at least in part, by increasing Smad1 expression, phosphorylation, and translocation to the nucleus....

  7. Optimization of welding current waveform for dissimilar material with DP590 and Al5052 by Delta-spot welding process

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ji Sun; Kim, In Ju; Kim, Young Gon [Korea Institute of Industrial Technology, Gwangju (Korea, Republic of)

    2016-06-15

    The automotive industry has a target goal to improve fuel consumption due to restricted exhaust gas regulation. For this reason, the applicability of lightweight material, Al alloys, Mg alloys is also being expanded. In this concept, high strength steel, DP590 and light alloy, AL5052 are joined in the right place of the car body. However, it is difficult to join to steel and aluminum by conventional fusion welding. Generally, in respect to dissimilar metal joining by fusion welding, intermetallic compound layer is formed at the joint interface, hot cracking is generated. In this study, the effect of the current waveform on the mechanical characteristics and microstructure in Delta spot welding process of dissimilar metal was investigated. As results, Intermetallic compound (IMC) layer was reduced from 2.355 μm to 1.09 μm by using Delta spot welding process; also the welding current range improved by 50% in the delta spot welding, higher than in the inverter resistance welding. To conclude, the delta spot welding process adopting the process tapes contributes to improving the welding quality for dissimilar metals (Al5052 and DP590) due to a decrease in IMC layer.

  8. Fgf signaling controls pharyngeal taste bud formation through miR-200 and Delta-Notch activity.

    Science.gov (United States)

    Kapsimali, Marika; Kaushik, Anna-Lila; Gibon, Guillaume; Dirian, Lara; Ernest, Sylvain; Rosa, Frederic M

    2011-08-01

    Taste buds, the taste sensory organs, are conserved in vertebrates and composed of distinct cell types, including taste receptor, basal/presynaptic and support cells. Here, we characterize zebrafish taste bud development and show that compromised Fgf signaling in the larva results in taste bud reduction and disorganization. We determine that Fgf activity is required within pharyngeal endoderm for formation of Calb2b(+) cells and reveal miR-200 and Delta-Notch signaling as key factors in this process. miR-200 knock down shows that miR-200 activity is required for taste bud formation and in particular for Calb2b(+) cell formation. Compromised delta activity in mib(-/-) dramatically reduces the number of Calb2b(+) cells and increases the number of 5HT(+) cells. Conversely, larvae with increased Notch activity and ascl1a(-/-) mutants are devoid of 5HT(+) cells, but have maintained and increased Calb2b(+) cells, respectively. These results show that Delta-Notch signaling is required for intact taste bud organ formation. Consistent with this, Notch activity restores Calb2b(+) cell formation in pharyngeal endoderm with compromised Fgf signaling, but fails to restore the formation of these cells after miR-200 knock down. Altogether, this study provides genetic evidence that supports a novel model where Fgf regulates Delta-Notch signaling, and subsequently miR-200 activity, in order to promote taste bud cell type differentiation.

  9. Evaluating trade-offs of a large, infrequent sediment diversion for restoration of a forested wetland in the Mississippi delta

    Science.gov (United States)

    Rutherford, Jeffrey S.; Day, John W.; D'Elia, Christopher F.; Wiegman, Adrian R. H.; Willson, Clinton S.; Caffey, Rex H.; Shaffer, Gary P.; Lane, Robert R.; Batker, David

    2018-04-01

    Flood control levees cut off the supply of sediment to Mississippi delta coastal wetlands, and contribute to putting much of the delta on a trajectory for continued submergence in the 21st century. River sediment diversions have been proposed as a method to provide a sustainable supply of sediment to the delta, but the frequency and magnitude of these diversions needs further assessment. Previous studies suggested operating river sediment diversions based on the size and frequency of natural crevasse events, which were large (>5000 m3/s) and infrequent (active builds on these previous works by quantitatively assessing tradeoffs for a large, infrequent diversion into the forested wetlands of the Maurepas swamp. Land building was estimated for several diversion sizes and years inactive using a delta progradation model. A benefit-cost analysis (BCA) combined model land building results with an ecosystem service valuation and estimated costs. Results demonstrated that land building is proportional to diversion size and inversely proportional to years inactive. Because benefits were assumed to scale linearly with land gain, and costs increase with diversion size, there are disadvantages to operating large diversions less often, compared to smaller diversions more often for the immediate project area. Literature suggests that infrequent operation would provide additional gains (through increased benefits and reduced ecosystem service costs) to the broader Lake Maurepas-Pontchartrain-Borgne ecosystem. Future research should incorporate these additional effects into this type of BCA, to see if this changes the outcome for large, infrequent diversions.

  10. Design and implementation of quadrature bandpass sigma-delta modulator used in low-IF RF receiver

    Science.gov (United States)

    Ge, Binjie; Li, Yan; Yu, Hang; Feng, Xiaoxing

    2018-05-01

    This paper presents the design and implementation of quadrature bandpass sigma-delta modulator. A pole movement method for transforming real sigma-delta modulator to a quadrature one is proposed by detailed study of the relationship of noise-shaping center frequency and integrator pole position in sigma-delta modulator. The proposed modulator uses sampling capacitor sharing switched capacitor integrator, and achieves a very small feedback coefficient by a series capacitor network, and those two techniques can dramatically reduce capacitor area. Quantizer output-dependent dummy capacitor load for reference voltage buffer can compensate signal-dependent noise that is caused by load variation. This paper designs a quadrature bandpass Sigma-Delta modulator for 2.4 GHz low IF receivers that achieve 69 dB SNDR at 1 MHz BW and -1 MHz IF with 48 MHz clock. The chip is fabricated with SMIC 0.18 μm CMOS technology, it achieves a total power current of 2.1 mA, and the chip area is 0.48 mm2. Project supported by the National Natural Science Foundation of China (Nos. 61471245, U1201256), the Guangdong Province Foundation (No. 2014B090901031), and the Shenzhen Foundation (Nos. JCYJ20160308095019383, JSGG20150529160945187).

  11. Testing optically stimulated luminescence dating on sand-sized quartz of deltaic deposits from the Sperchios delta plain, central Greece

    Directory of Open Access Journals (Sweden)

    Evangelos Tsakalos

    2018-04-01

    Full Text Available This study reports on the first investigation into the potential of luminescence dating to establish a chronological framework for the depositional sequences of the Sperchios delta plain, central Greece. A series of three borehole cores (20 m deep and two shallow cores (4 m deep, from across the delta plain, were extracted, and samples were collected for luminescence dating. The luminescence ages of sand-sized quartz grains were obtained from small aliquots of quartz, using the Single-Aliquot Regenerative-dose (SAR protocol. The equivalent dose determination included a series of tests and the selection of the Minimum Age Model (MAM as the most appropriate statistical model. This made it possible to confirm the applicability of quartz Optically Stimulated Luminescence (OSL dating to establish absolute chronology for deltaic sediments from the Sperchios delta plain.Testing age results of the five cores showed that the deltaic sediments were deposited during the Holocene. A relatively rapid deposition is implied for the top ∼14 m possibly as a result of the deceleration in the rate of the sea-level rise and the transition to terrestrial conditions, while on the deeper parts, the reduced sedimentation rate may indicate a lagoonal or coastal environment. Keywords: Luminescence dating, Holocene, Sedimentation rates, Deltaic deposits, Sperchios delta plain, Central Greece

  12. High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia

    Directory of Open Access Journals (Sweden)

    J.A.B. Chies

    2003-01-01

    Full Text Available Homozygous sickle cell disease (SCD has a wide spectrum of clinical manifestations. In Brazil, the main cause of death of individuals with SCD is recurrent infection. The CCR5delta32 allele, which confers relative resistance to macrophage-tropic HIV virus infection, probably has reached its frequency and world distribution due to other pathogens that target macrophage in European populations. In the present investigation a relatively higher prevalence (5.1% of the CCR5delta32 allele was identified, by PCR amplification using specific primers, in 79 SCD patients when compared to healthy controls (1.3% with the same ethnic background (Afro-Brazilians. Based on a hypothesis that considers SCD as a chronic inflammatory condition, and since the CCR5 chemokine receptor is involved in directing a Th1-type immune response, we suggest that a Th1/Th2 balance can influence the morbidity of SCD. If the presence of the null CCR5delta32 allele results in a reduction of the chronic inflammation state present in SCD patients, this could lead to differential survival of SCD individuals who are carriers of the CCR5delta32 allele. This differential survival could be due to the development of less severe infections and consequently reduced or less severe vaso-occlusive crises.

  13. Preparing the Dutch delta for future droughts: model based support in the national Delta Programme

    Science.gov (United States)

    ter Maat, Judith; Haasnoot, Marjolijn; van der Vat, Marnix; Hunink, Joachim; Prinsen, Geert; Visser, Martijn

    2014-05-01

    Keywords: uncertainty, policymaking, adaptive policies, fresh water management, droughts, Netherlands, Dutch Deltaprogramme, physically-based complex model, theory-motivated meta-model To prepare the Dutch Delta for future droughts and water scarcity, a nation-wide 4-year project, called Delta Programme, is established to assess impacts of climate scenarios and socio-economic developments and to explore policy options. The results should contribute to a national adaptive plan that is able to adapt to future uncertain conditions, if necessary. For this purpose, we followed a model-based step-wise approach, wherein both physically-based complex models and theory-motivated meta-models were used. First step (2010-2011) was to make a quantitative problem description. This involved a sensitivity analysis of the water system for drought situations under current and future conditions. The comprehensive Dutch national hydrological instrument was used for this purpose and further developed. Secondly (2011-2012) our main focus was on making an inventory of potential actions together with stakeholders. We assessed efficacy, sell-by date of actions, and reassessed vulnerabilities and opportunities for the future water supply system if actions were (not) taken. A rapid assessment meta-model was made based on the complex model. The effects of all potential measures were included in the tool. Thirdly (2012-2013), with support of the rapid assessment model, we assessed the efficacy of policy actions over time for an ensemble of possible futures including sea level rise and climate and land use change. Last step (2013-2014) involves the selection of preferred actions from a set of promising actions that meet the defined objectives. These actions are all modeled and evaluated using the complex model. The outcome of the process will be an adaptive management plan. The adaptive plan describes a set of preferred policy pathways - sequences of policy actions - to achieve targets under

  14. Hydrology and morphology of two river mouth regions (temperate Vistula Delta and subtropical Red River Delta

    Directory of Open Access Journals (Sweden)

    Zbigniew Pruszak

    2005-09-01

    Full Text Available The paper presents a comparative analysis of two different river mouths from two different geographical zones (subtropical and temperate climatic regions. One is the multi-branch and multi-spit mouth of the Red River on the Gulf of Tonkin (Vietnam, the other is the smaller delta of the river Vistula on a bay of the Baltic Sea (Poland. The analysis focuses on the similarities and differences in the hydrodynamics between these estuaries and the adjacent coastal zones, the features of sediment transport, and the long-term morphodynamics of the river outlets. Salinity and water level are also discussed, the latter also in the context of the anticipated global effect of accelerated sea level rise. The analysis shows that the climatic and environmental conditions associated with geographical zones give rise to fundamental differences in the generation and dynamic evolution of the river mouths.

  15. Community structure of spiders in coastal habitats of a Mediterranean delta region (Nestos Delta, NE Greece

    Directory of Open Access Journals (Sweden)

    S. Buchholz

    2009-01-01

    Full Text Available (pp 101-115Habitat zonation and ecology of spider assemblages have been poorly studied in Mediterranean ecosystems. A first analysis of spider assemblages in coastal habitats in the east Mediterranean area is presented. The study area is the 250 km² Nestos Delta, located in East Macedonia in the North-East of Greece. Spiders were caught in pitfall traps at 17 sites from the beginning of April to the end of June 2004. Nonparametric estimators were used to determine species richness and alpha diversity. Ordination analysis (redundancy analysis indicated four clearly separable spider species groups (salt meadows, dunes, mea-dows and floodplain forests, along a soil salinity and moisture gradient. Based on these results we discuss the habitat preferences of these spiders and include the first ecological data on several species.

  16. Levee Seepage Detection in the Sacramento-San Joaquin Delta Using Polarimetric SAR

    Science.gov (United States)

    An, K.; Jones, C. E.; Bekaert, D. P.

    2017-12-01

    The Sacramento-San Joaquin Delta's extensive levee system protects over 2,800 km2 of reclaimed lands and serves as the main irrigation and domestic water supply for the state of California. However, ongoing subsidence and disaster threats from floods and earthquakes make the Delta levee system highly vulnerable, endangering water supplies for 23 million California residents and 2.5 million acres of agricultural land. Levee failure in the Delta can cause saltwater intrusion from San Francisco Bay, reducing water quality and curtailing water exports to residents, commercial users, and farmers. To protect the Delta levee system, it is essential to search for signs of seepage in which water is piping through or beneath levees, which can be associated with deformation of the levees themselves. Until now, in-situ monitoring has largely been applied, however, this is a time-consuming and expensive approach. We use data acquired with NASA's UAVSAR (Uninhabited Aerial Vehicle Synthetic Aperture Radar) airborne radar instrument to identify and characterize levee seepages and associated land subsidence through advanced remote sensing technologies. The high spatial resolution of UAVSAR can help to direct surveys to areas that are likely to be experiencing damage. UAVSAR is an L-band airborne sensor with high signal-to-noise ratio, repeat flight track accuracy, and spatial resolution of 7x7 m2 (for multi-looked products) that is necessary for detailed levee monitoring. The adaptability of radar instruments in their ability to see through smoke, haze, and clouds during the day or night, is especially relevant during disaster events, when cloud cover or lack of solar illumination inhibits traditional visual surveys of damage. We demonstrate the advantages of combining polarimetric radar imagery with geographic information systems (GIS) datasets in locating seepage features along critical levee infrastructure in the Delta for 2009-2016. The ability to efficiently locate potential

  17. HIV/AIDS, artisanal fishing and food security in the Okavango Delta, Botswana

    Science.gov (United States)

    Ngwenya, B. N.; Mosepele, K.

    . Subsequently, household food security is seriously affected because fish provides a significant proportion of food to CIP households where approximately 55% of households get their food from fish products. During food shortages, CIP households resorted to a hierarchy of strategies which included cutting down on meals or reducing meal portions, looking for paid work, gathering wild fruit, asking for food from relatives, selling livestock, and getting social assistance. In conclusion, artisanal fishing is a natural safety net which constitutes an important buffer for households affected by HIV/AIDS-related stressors in the Okavango Delta. Access to fish helps these households mitigate potentially adverse impacts such as deterioration into chronic poverty.

  18. Geochronology of priority pollutants in sedimentation zones of the Volga and Danube delta in comparison with the Rhine delta

    International Nuclear Information System (INIS)

    Winkels, H.J.; Kroonenberg, S.B.; Lychagin, M.Y.; Marin, G.; Rusakov, G.V.; Kasimov, N.S.

    1998-01-01

    Six sediment cores were taken in sedimentation zones of the Volga river (located in the southern part of the Russian Federation) and, additionally, 6 sediment cores were taken in several lakes (sedimentation zones) in the central and western part of the Danube delta in Romania. Priority pollutants (8 metals, 7 polychlorinated biphenyls and 10 polycyclic aromatic hydrocarbons) were determined in all samples of all cores. Present-day and historical levels of pollutants since the late 1930s were established through the use of radionuclide time tracers ( 137 Cs, 134 Cs). For the persistent metals and polycyclic aromatic hydrocarbons, trends in the concentration profiles during the last 5 decades are described. Low and hardly changing concentrations of As, Cu, Zn and all studied PAHs were observed during the last five decades in the sediments of the Volga river. Recently deposited sediments show slightly increasing levels for the heavy metals Zn and Cr and As in the Volga delta. For the studied metals and PAHs, maximum concentrations were found around 1987 in the sediments of the Danube delta. Sediments deposited around 1940 and recently deposited sediments in the Danube delta showed lower pollutant levels. If the contents of heavy metals, PAHs and PCBs in the aquatic sediments in the deltas of the rivers Rhine, Danube and Volga are compared, it is clear that the Volga delta is and was the cleanest delta during the last 5 decades. Nowadays the contents of heavy metals (except Cu and Ni), PAHs and PCBs in the aquatic sediments of the river Rhine are still highest compared to the other two rivers. The recent load of heavy metals (except Cd and Zn) in the sediments of the river Danube is the highest compared to the other two rivers. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  19. The case for selection at CCR5-Delta32.

    Directory of Open Access Journals (Sweden)

    2005-11-01

    Full Text Available The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32 allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequency (5%-14% in Europe as a result of strong positive selection, perhaps by such selective agents as the bubonic plague or smallpox during the Middle Ages. This hypothesis was based on several lines of evidence, including the absence of the allele outside of Europe and long-range linkage disequilibrium at the locus. We reevaluated this evidence with the benefit of much denser genetic maps and extensive control data. We find that the pattern of genetic variation at CCR5-Delta32 does not stand out as exceptional relative to other loci across the genome. Moreover using newer genetic maps, we estimated that the CCR5-Delta32 allele is likely to have arisen more than 5,000 y ago. While such results can not rule out the possibility that some selection may have occurred at C-C chemokine receptor 5 (CCR5, they imply that the pattern of genetic variation seen atCCR5-Delta32 is consistent with neutral evolution. More broadly, the results have general implications for the design of future studies to detect the signs of positive selection in the human genome.

  20. Delta Cafés (Portugal: Sustainable Business Development

    Directory of Open Access Journals (Sweden)

    Olgierd Swiatkiewicz

    2017-12-01

    Full Text Available In the case study of Delta Cafés we discuss the sustainable development of the Portuguese company and brand over the 55 years of their existence. Delta Cafés has already been analyzed in terms of marketing activity, social responsibility, management control systems, etc. In this paper, we refer to these studies, and we reach the sources, i.e. the information provided by the Delta Cafés itself. Due to the nature of the coffee market and the use of case study methodology, we start the presentation of this case from a broader context, describing the coffee market in the world and characterizing the coffee market in Portugal as well. Then we present the history of the development of the company and the brand Delta Cafés. The paper ends with concluding remarks in which we discuss the issues of social and environmental responsibility in the light of the development of Delta Cafés business and brand strategies. 

  1. The case for selection at CCR5-Delta32.

    Directory of Open Access Journals (Sweden)

    Pardis C Sabeti

    2005-11-01

    Full Text Available The C-C chemokine receptor 5, 32 base-pair deletion (CCR5-Delta32 allele confers strong resistance to infection by the AIDS virus HIV. Previous studies have suggested that CCR5-Delta32 arose within the past 1,000 y and rose to its present high frequency (5%-14% in Europe as a result of strong positive selection, perhaps by such selective agents as the bubonic plague or smallpox during the Middle Ages. This hypothesis was based on several lines of evidence, including the absence of the allele outside of Europe and long-range linkage disequilibrium at the locus. We reevaluated this evidence with the benefit of much denser genetic maps and extensive control data. We find that the pattern of genetic variation at CCR5-Delta32 does not stand out as exceptional relative to other loci across the genome. Moreover using newer genetic maps, we estimated that the CCR5-Delta32 allele is likely to have arisen more than 5,000 y ago. While such results can not rule out the possibility that some selection may have occurred at C-C chemokine receptor 5 (CCR5, they imply that the pattern of genetic variation seen at CCR5-Delta32 is consistent with neutral evolution. More broadly, the results have general implications for the design of future studies to detect the signs of positive selection in the human genome.

  2. The small delta antigen of hepatitis delta virus is an acetylated protein and acetylation of lysine 72 may influence its cellular localization and viral RNA synthesis

    International Nuclear Information System (INIS)

    Mu, J.-J.; Tsay, Y.-G.; Juan, L.-J.; Fu, T.-F.; Huang, W.-H.; Chen, D.-S.; Chen, P.-J.

    2004-01-01

    Hepatitis delta virus (HDV) is a single-stranded RNA virus that encodes two viral nucleocapsid proteins named small and large form hepatitis delta antigen (S-HDAg and L-HDAg). The S-HDAg is essential for viral RNA replication while the L-HDAg is required for viral assembly. In this study, we demonstrated that HDAg are acetylated proteins. Metabolic labeling with [ 3 H]acetate revealed that both forms of HDAg could be acetylated in vivo. The histone acetyltransferase (HAT) domain of cellular acetyltransferase p300 could acetylate the full-length and the N-terminal 88 amino acids of S-HDAg in vitro. By mass spectrometric analysis of the modified protein, Lys-72 of S-HDAg was identified as one of the acetylation sites. Substitution of Lys-72 to Arg caused the mutant S-HDAg to redistribute from the nucleus to the cytoplasm. The mutant reduced viral RNA accumulation and resulted in the earlier appearance of L-HDAg. These results demonstrated that HDAg is an acetylated protein and mutation of HDAg at Lys-72 modulates HDAg subcellular localization and may participate in viral RNA nucleocytoplasmic shuttling and replication

  3. Critical Assessment of the Delta Smelt Population in the San Francisco Estuary, California

    Directory of Open Access Journals (Sweden)

    William A Bennett

    2005-09-01

    abundance is difficult. Although delta smelt recently performed well enough to meet the current restoration criteria, analyses presented here suggest that there is still a high probability that the population will decline in the near future; the most recent abundance index (2004 is the lowest on record. Overall, the limited distribution, short life span and low reproductive capacity, as well as relatively strict physical and feeding requirements, are indications that delta smelt is at risk to catastrophe in a fluctuating environment. Unfortunately, options for avoiding potential declines through management and restoration are currently limited by large gaps in knowledge. Monitoring of spring water temperatures, however, may provide a useful tool for determining when to reduce entrainment in water export facilities. Actions that target carrying capacity may ultimately provide the most benefit, but it is not clear how that can be achieved given the current state of knowledge, and the limited tools available for restoration. Overall, a better understanding of the life history, habitat requirements, and limiting factors will be essential for developing tools for management and restoration. Therefore, given the implications for managing California water supply and the current state of population abundance, a good investment would be to fill the critical data gaps outlined here through a comprehensive program of research.

  4. Oxygen Nonstoichiometry and Defect Chemistry Modeling of Ce0.8Pr0.2O2-delta

    DEFF Research Database (Denmark)

    Chatzichristodoulou, Christodoulos; Hendriksen, Peter Vang

    2010-01-01

    (DeltaHPrexc=aHdelta) and a completely random distribution of defects (referred to as “delta-linear”), or a “generalized delta-linear” solution model, where the excess Gibbs energy change in the reduction reaction of the dopant linearly varies with delta (DeltaGPrexc=aGdelta). A comparison of the partial...

  5. Fracture Analyses of Cracked Delta Eye Plates in Ship Towing

    Science.gov (United States)

    Huang, Xiangbing; Huang, Xingling; Sun, Jizheng

    2018-01-01

    Based on fracture mechanics, a safety analysis approach is proposed for cracked delta eye plates in ship towing. The static analysis model is presented when the delta eye plate is in service, and the fracture criterion is introduced on basis of stress intensity factor, which is estimated with domain integral method. Subsequently, three-dimensional finite element analyses are carried out to obtain the effective stress intensity factors, and a case is studied to demonstrate the reasonability of the approach. The results show that the classical strength theory is not applicable to evaluate the cracked plate while fracture mechanics can solve the problem very well, and the load level, which a delta eye plate can carry on, decreases evidently when it is damaged.

  6. Cystic fibrosis Delta F508 heterozygotes, smoking, and reproduction

    DEFF Research Database (Denmark)

    Dahl, Morten; Tybjaerg-Hansen, A; Wittrup, H H

    1998-01-01

    Cystic fibrosis is the most common fatal autosomal recessive disease affecting Caucasian populations. It remains a puzzle how this disease is maintained at such a remarkably high incidence, however, it could be due to a reproductive advantage in cystic fibrosis heterozygotes. We tested this hypot......Cystic fibrosis is the most common fatal autosomal recessive disease affecting Caucasian populations. It remains a puzzle how this disease is maintained at such a remarkably high incidence, however, it could be due to a reproductive advantage in cystic fibrosis heterozygotes. We tested.......001). In conclusion, overall these results do not support a reproductive advantage for cystic fibrosis DeltaF508 heterozygotes. However, the data cannot totally exclude the possibility that nonsmoking DeltaF508 heterozygotes experience a reproductive advantage while smoking DeltaF508 heterozygotes experience...... the opposite, a reproductive disadvantage. Accordingly, the data suggest a previously undocumented role of smoking on fecundity among cystic fibrosis heterozygotes....

  7. Implementation of an ESA delta-DOR capability

    Science.gov (United States)

    James, Nick; Abello, Ricard; Lanucara, Marco; Mercolino, Mattia; Maddè, Roberto

    2009-06-01

    This paper describes the implementation of delta-DOR (delta-differential one-way ranging) receivers within the ESA Deep Space ground station network. Delta-DOR provides very accurate plane-of-sky measurements of spacecraft position which complement existing line-of-sight ranging and Doppler measurements. We discuss how this technique has been adapted and implemented at the two ESA deep-space ground stations using existing equipment and infrastructure. These new capabilities were added by writing new software modules for the standard ESA digital receiver (the intermediate frequency modem system—IFMS). With these upgrades the receiver has the ability to record accurately timetagged signals from up to eight IF sub-channels. These sub-channels can have bandwidths of 50 kHz-2 MHz with a sample quantization of 1-16 bits per component. The IF samples are stored locally for subsequent retrieval over a WAN by the correlator facility at ESOC.

  8. Parametrization of the. delta. residue function. [Complex functions

    Energy Technology Data Exchange (ETDEWEB)

    Vasan, S S [Carnegie-Mellon Univ., Pittsburgh, Pa. (USA). Dept. of Physics

    1976-04-19

    The complex residues at the ..delta..(1236) and ..delta..(1950) poles in the relevant partial-wave amplitudes provide information on the behaviour of the ..delta.. Regge residue function in the resonance region u>0. Attempts to incorporate this information in parametrizations of the residue by functions that are real on the real u-axis result in residues which have unsatisfactory behaviour in the region u<1GeV/sup 2/. The choice of complex functions for the trajectory and residue removes this undesirable feature and provides a better representation of the residue in the resonance region, suggesting that complex parametrizations would be better suited to Regge analyses of near-backward scattering.

  9. Effects of external influences in subsonic delta wing vortices

    Science.gov (United States)

    Washburn, Anthony E.

    1992-01-01

    An experimental investigation was conducted to examine inconsistencies in reported studies for the vortical flow over highly-swept delta wings. A 76-deg swept delta wing was tested in three facilities with open and closed test sections and different model-support systems. The results obtained include surface oil-flow patterns, off-body laser-light-sheet flow visualization, and aerodynamic load measurements. Parameters such as the wall boundaries and model-support systems can drastically alter the loads. The effect of a high level of free-stream turbulence on the delta-wing flowfield was also examined and found to be significant. The increase in free-stream turbulence caused boundary-layer transition, unsteadiness in the vortex core positions, and altered the loads and moments.

  10. [Transport characteristics of air pollutants over the Yangtze Delta].

    Science.gov (United States)

    Wang, Yan; Chai, Fa-He; Wang, Yong-Hong; Liu, Ming

    2008-05-01

    Meteorological field of January, April, July and October in 2004 was obtained by running MM5 with NCEP datasets. Then we used HYSPLIT 4.8 model to calculate the backward and forward trajectories of representative cities. Distributions of trajectories and the affected areas vary with seasons. Transport current affecting Yangtze River Delta is mainly from Mongolia, North China or Northeast region, via Yellow Sea area, Shandong, Jiangsu province or Shanghai. Another important transport path is current from southwest because of the Southwest monsoon. A movement of East Asia monsoon plays an important part in the mesoscale transport of pollutants in Yangtze Delta. Winter monsoon is a main mechanism which moves the air pollutants in Yangtze Delta to South China and West Pacific ocean. Another important transport system is the subtropical anticyclone over the western Pacific Ocean which controls the east coast of our country in spring and summer. This circulation system mainly affects the inland area of our country.

  11. Dendroclimatology of the Slave River Delta, Northwest Territories, Canada

    Science.gov (United States)

    Jarvis, S.; Buhay, W. M.; Blair, D.; Tardif, J.; Bailey, D.

    2004-05-01

    It is well documented that changing hydrological conditions impact delta ecosystems. Such changes can also affect local inhabitants who have historical connections to the area and its resources. During the summer of 2003 a multifaceted paleo-environmental project was initiated to reconstruct the frequencies of floods and droughts in the Slave River Delta (SRD), Northwest Territories, Canada. The project goal is to forecast future hydrological and ecological conditions in the SRD in light of anticipated climate change and increasing demand on water resources. With the intent of expanding the climate history of the SRD, this particular aspect of the project will employ white spruce tree-ring chronologies constructed from six sites visited within the delta. Work is currently in progress to build a master chronology estimated to span over 300 years. In addition, a climate model for the SRD is also being developed and will be highlighted.

  12. Oral Zinc Supplementation Reduces the Erythropoietin Responsiveness Index in Patients on Hemodialysis

    Directory of Open Access Journals (Sweden)

    Hiroki Kobayashi

    2015-05-01

    Full Text Available Background: In hemodialysis (HD patients, zinc depletion caused by inadequate intake, malabsorption, and removal by HD treatment leads to erythropoiesis-stimulating agent (ESA hyporesponsiveness. This study investigated the effects of zinc supplementation in HD patients with zinc deficiency on changes in the erythropoietin responsiveness index (ERI. Methods: Patients on HD with low serum zinc levels (<65 μg/dL were randomly assigned to two groups: The polaprezinc group (who received daily polaprezinc, containing 34 mg/day of zinc (n = 35 and the control group (no supplementation (n = 35 for 12 months. All the 70 patients had been taking epoetin alpha as treatment for renal anemia. ERI was measured with the following equation: Weekly ESA dose (units/dry weight (kg/hemoglobin (g/dL. Results: There were no significant changes in hemoglobin levels within groups or between the control and polaprezinc groups during the study period. Although reticulocyte counts were increased immediately after zinc supplementation, this change was transient. Serum zinc levels were significantly increased and serum copper levels were significantly decreased in the polaprezinc group after three months; this persisted throughout the study period. Although there was no significant change in the serum iron or transferrin saturation levels in the polaprezinc group during the study period, serum ferritin levels significantly decreased following polaprezinc treatment. Further, in the polaprezinc group, ESA dosage and ERI were significantly decreased at 10 months and nine months, respectively, as compared with the baseline value. Multiple stepwise regression analysis revealed that the change in the serum zinc level was an independent predictor of lowered ERI. Conclusions: Zinc supplementation reduces ERI in patients undergoing HD and may be a novel therapeutic strategy for patients with renal anemia and low serum zinc levels.

  13. Dynamic controls on shallow clinoform geometry: Mekong Delta, Vietnam

    Science.gov (United States)

    Eidam, E. F.; Nittrouer, C. A.; Ogston, A. S.; DeMaster, D. J.; Liu, J. P.; Nguyen, T. T.; Nguyen, T. N.

    2017-09-01

    Compound deltas, composed of a subaerial delta plain and subaqueous clinoform, are common termini of large rivers. The transition between clinoform topset and foreset, or subaqueous rollover point, is located at 25-40-m water depth for many large tide-dominated deltas; this depth is controlled by removal of sediment from the topset by waves, currents, and gravity flows. However, the Mekong Delta, which has been classified as a mixed-energy system, has a relatively shallow subaqueous rollover at 4-6-m depth. This study evaluates dynamical measurements and seabed cores collected in Sep 2014 and Mar 2015 to understand processes of sediment transfer across the subaqueous delta, and evaluate possible linkages to geometry. During the southwest rainy monsoon (Sep 2014), high river discharge, landward return flow under the river plume, and regional circulation patterns facilitated limited sediment flux to the topset and foreset, and promoted alongshore flux to the northeast. Net observed sediment fluxes in Sep 2014 were landward, however, consistent with hypotheses about seasonal storage on the topset. During the northeast rainy monsoon, low river discharge and wind-driven currents facilitated intense landward and southwestward fluxes of sediment. In both seasons, bed shear velocities frequently exceeded the 0.01-0.02 m/s threshold of motion for sand, even in the absence of strong wave energy. Most sediment transport occurred at water depths 4 cm/yr at energy-limited, and thus rollover depths cannot be predicted solely by bed-stress distributions. In systems like the subaqueous Mekong Delta, direction of transport may have a key impact on morphology.

  14. Structure of the [delta]-opioid receptor bound to naltrindole

    Energy Technology Data Exchange (ETDEWEB)

    Granier, Sébastien; Manglik, Aashish; Kruse, Andrew C.; Kobilka, Tong Sun; Thian, Foon Sun; Weis, William I.; Kobilka, Brian K. (Stanford-MED)

    2012-07-11

    The opioid receptor family comprises three members, the {mu}-, {delta}- and {kappa}-opioid receptors, which respond to classical opioid alkaloids such as morphine and heroin as well as to endogenous peptide ligands like endorphins. They belong to the G-protein-coupled receptor (GPCR) superfamily, and are excellent therapeutic targets for pain control. The {delta}-opioid receptor ({delta}-OR) has a role in analgesia, as well as in other neurological functions that remain poorly understood. The structures of the {mu}-OR and {kappa}-OR have recently been solved. Here we report the crystal structure of the mouse {delta}-OR, bound to the subtype-selective antagonist naltrindole. Together with the structures of the {mu}-OR and {kappa}-OR, the {delta}-OR structure provides insights into conserved elements of opioid ligand recognition while also revealing structural features associated with ligand-subtype selectivity. The binding pocket of opioid receptors can be divided into two distinct regions. Whereas the lower part of this pocket is highly conserved among opioid receptors, the upper part contains divergent residues that confer subtype selectivity. This provides a structural explanation and validation for the 'message-address' model of opioid receptor pharmacology, in which distinct 'message' (efficacy) and 'address' (selectivity) determinants are contained within a single ligand. Comparison of the address region of the {delta}-OR with other GPCRs reveals that this structural organization may be a more general phenomenon, extending to other GPCR families as well.

  15. Stable isotope deltas: Tiny, yet robust signatures in nature

    Science.gov (United States)

    Brand, Willi A.; Coplen, Tyler B.

    2012-01-01

    Although most of them are relatively small, stable isotope deltas of naturally occurring substances are robust and enable workers in anthropology, atmospheric sciences, biology, chemistry, environmental sciences, food and drug authentication, forensic science, geochemistry, geology, oceanography, and paleoclimatology to study a variety of topics. Two fundamental processes explain the stable isotope deltas measured in most terrestrial systems: isotopic fractionation and isotope mixing. Isotopic fractionation is the result of equilibrium or kinetic physicochemical processes that fractionate isotopes because of small differences in physical or chemical properties of molecular species having different isotopes. It is shown that the mixing of radioactive and stable isotope end members can be modelled to provide information on many natural processes, including 14C abundances in the modern atmosphere and the stable hydrogen and oxygen isotopic compositions of the oceans during glacial and interglacial times. The calculation of mixing fractions using isotope balance equations with isotope deltas can be substantially in error when substances with high concentrations of heavy isotopes (e.g. 13C, 2H, and 18O ) are mixed. In such cases, calculations using mole fractions are preferred as they produce accurate mixing fractions. Isotope deltas are dimensionless quantities. In the International System of Units (SI), these quantities have the unit 1 and the usual list of prefixes is not applicable. To overcome traditional limitations with expressing orders of magnitude differences in isotope deltas, we propose the term urey (symbol Ur), after Harold C. Urey, for the unit 1. In such a manner, an isotope delta value expressed traditionally as−25 per mil can be written as−25 mUr (or−2.5 cUr or−0.25 dUr; the use of any SI prefix is possible). Likewise, very small isotopic differences often expressed in per meg ‘units’ are easily included (e.g. either+0.015 ‰ or+15 per meg

  16. DNA repair synthesis in human fibroblasts requires DNA polymerase delta

    International Nuclear Information System (INIS)

    Nishida, C.; Reinhard, P.; Linn, S.

    1988-01-01

    When UV-irradiated cultured diploid human fibroblasts were permeabilized with Brij-58 then separated from soluble material by centrifugation, conservative DNA repair synthesis could be restored by a soluble factor obtained from the supernatant of similarly treated HeLa cells. Extensive purification of this factor yielded a 10.2 S, 220,000-dalton polypeptide with the DNA polymerase and 3'- to 5'-exonuclease activities reported for DNA polymerase delta II. Monoclonal antibody to KB cell DNA polymerase alpha, while binding to HeLa DNA polymerase alpha, did not bind to the HeLa DNA polymerase delta. Moreover, at micromolar concentrations N2-(p-n-butylphenyl)-2'-deoxyguanosine 5'-triphosphate (BuPdGTP) and 2-(p-n-butylanilino)-2'-deoxyadenosine 5'-triphosphate (BuAdATP) were potent inhibitors of DNA polymerase alpha, but did not inhibit the DNA polymerase delta. Neither purified DNA polymerase alpha nor beta could promote repair DNA synthesis in the permeabilized cells. Furthermore, under conditions which inhibited purified DNA polymerase alpha by greater than 90%, neither monoclonal antibodies to DNA polymerase alpha, BuPdGTP, nor BuAdATP was able to inhibit significantly the DNA repair synthesis mediated by the DNA polymerase delta. Thus, it appears that a major portion of DNA repair synthesis induced by UV irradiation might be catalyzed by DNA polymerase delta. When xeroderma pigmentosum human diploid fibroblasts were utilized, DNA repair synthesis dependent upon ultraviolet light could be restored by addition of both T4 endonuclease V and DNA polymerase delta, but not by addition of either one alone

  17. Nigeria. Petroleum, pollution and poverty in the Niger Delta

    International Nuclear Information System (INIS)

    2009-06-01

    The oil industry has operated in the Niger Delta in Nigeria for more than half a century - bringing almost no benefit to the people living there. Instead, widespread and unchecked human rights violations have pushed many people deeper into poverty and deprivation, fuelled conflict and led to a pervasive sense of powerlessness and frustration. This multidimensional crisis is driven by many factors - abuses committed by the security forces and militant groups, extensive pollution of land and water, corruption, serious corporate bad practice and government neglect. Nigeria: Petroleum, pollution and poverty in the Niger Delta focuses on one dimension of the crisis: the impact of pollution and environmental damage caused by the oil industry on the human rights of those living in the Niger Delta. Many people in the oil-producing areas of the delta rely on fisheries, subsistence agriculture and associated processing industries for their livelihood. Decades of pollution and environmental damage have resulted in violations of the right to an adequate standard of living - including food and water - violations of the right to gain a living through work, and violations of the right to health. The report examines who is responsible for this situation in a context where multinational oil companies have been operating for decades. It highlights how companies take advantage of the weak regulatory systems that characterize many poor countries, and how the poorest people are often the most vulnerable to exploitation. The people of the Niger Delta have seen their human rights undermined by oil companies that their government can not - or will not - hold to account. They have been systematically denied access to information about how oil exploration and production will affect them, and are repeatedly denied access to justice. The Niger Delta provides a stark case study of the lack of accountability of a government to the people, and of multinational companies' almost total lack of

  18. Effects of drought on birds and riparian vegetation in the Colorado River Delta, Mexico

    Science.gov (United States)

    Hinojosa-Huerta, Osvel; Nagler, Pamela L.; Carrillo-Guererro, Yamilett K.; Glenn, Edward P.

    2013-01-01

    The riparian corridor in the delta of the Colorado River in Mexico supports internationally important bird habitat. The vegetation is maintained by surface flows from the U.S. and Mexico and by a high, non-saline aquifer into which the dominant phreatophytic shrubs and trees are rooted. We studied the effects of a regional drought on riparian vegetation and avian abundance and diversity from 2002 to 2007, during which time surface flows were markedly reduced compared to the period from 1995 to 2002. Reduced surface flows led to a reduction in native tree cover but an increase in shrub cover, mostly due to an increase in Tamarix spp., an introduced halophytic shrub, and a reduction in Populus fremontii and Salix gooddingii trees. However, overall vegetation cover was unchanged at about 70%. Overall bird density and diversity were also unchanged, but riparian-obligate species tended to decrease in abundance, and generalist species increased. Although reduction in surface flows reduced habitat value and negatively impacted riparian-obligate bird species, portions of the riparian zone exhibited resilience. Surface flows are required to reduce soil salt levels and germinate new cohorts of native trees, but the main source of water supporting this ecosystem is the aquifer, derived from underflows from irrigated fields in the U.S. and Mexico. The long-term prospects for delta riparian habitats are uncertain due to expected reduced flows of river water from climate change, and land use practices that will reduce underflows to the riparian aquifer and increase salinity levels. Active restoration programs would be needed if these habitats are to be preserved for the future.

  19. Carbon Stocks in Permafrost-Affected Soils of the Lena River Delta

    Science.gov (United States)

    Zubrzycki, S.; Kutzbach, L.; Grosse, G.; Desyatkin, A.; Pfeiffer, E.

    2012-12-01

    additionally corrected the extent of the first terrace's land area by reducing it by the percentage of small water ponds and cracks by 14% detected by high-resolution aerial photography for Samoylov Island. We scaled the area-weighted SSOC averages estimated for the two geomorphological units of Samoylov Island across the corrected total land areas of the Lena River Delta's first terrace (9,430 km2) and the active floodplains (3,470 km2) leading to total organic soil carbon storage estimates for a depth of 1 m of ~278 ± 98 Tg C and ~47 ± 26 Tg C, respectively [2]. References [1] Tarnocai, C., Canadell, J.G., Schuur, E.A.G., Kuhry, P. Mazhitova, G. & Zimov, S., 2009. Soil organic carbon pools in the northern circumpolar permafrost region. Global Biogeochemical Cycles 23, GB2023: 11p. [2] Zubrzycki, S., Kutzbach, L., Grosse, G., A. R. Desyatkin & E.-M. Pfeiffer (in prep.). Soil Organic Carbon Stocks in the Lena River Delta. In preparation for BGS.

  20. Delta progradation in Greenland driven by increasing glacial mass loss

    DEFF Research Database (Denmark)

    Bendixen, Mette; Iversen, Lars Lonsmann; Bjork, Anders Anker

    2017-01-01

    imagery. We find that delta progradation was driven by high freshwater runoff from the Greenland Ice Sheet coinciding with periods of open water. Progradation was controlled by the local initial environmental conditions (that is, accumulated air temperatures above 0 degrees C per year, freshwater runoff...... of erosion and accretion along the large deltas of the main rivers in the Arctic5-7. Our results improve the understanding of Arctic coastal evolution in a changing climate, and reveal the impacts on coastal areas of increasing ice mass loss and the associated freshwater runoff and lengthening of open-water...

  1. A divergent synthesis of the delta(13)-9-isofurans.

    Science.gov (United States)

    Taber, Douglass F; Gu, Peiming; Li, Rui

    2009-08-07

    A stereodivergent total synthesis of the Delta(13)-9-isofurans has been developed. The four core substituted tetrahydrofurans were prepared by the Sharpless asymmetric epoxidation and Sharpless asymmetric dihydroxylation followed by cascade cyclization. The relative configuration at C-8 was inverted by oxidation followed by immediate L-Selectride reduction. The relative configuration of the C-15 diastereomers was assigned by (S)-Binol/LAH/EtOH reduction of the corresponding enone. This synthesis of the Delta(13)-9-isofurans will provide sufficient material for further investigation of their biological activity.

  2. Halotolerance of Methanobacterium thermoautotrophicum delta H and Marburg.

    OpenAIRE

    Ciulla, R; Clougherty, C; Belay, N; Krishnan, S; Zhou, C; Byrd, D; Roberts, M F

    1994-01-01

    Methanobacterium thermoautotrophicum delta H and Marburg were adapted to grow in medium containing up to 0.65 M NaCl. From 0.01 to 0.5 M NaCl, there was a lag before cell growth which increased with increasing external NaCl. The effect of NaCl on methane production was not significant once the cells began to grow. Intracellular solutes were monitored by nuclear magnetic resonance (NMR) spectroscopy as a function of osmotic stress. In the delta H strain, the major intracellular small organic s...

  3. Changing Course - the Baird Team Solution: a Delta for All

    Science.gov (United States)

    Nairn, R. B.

    2016-02-01

    The Changing Course Design competition was initiated to evaluate options for re-positioning the mouth of the Mississippi River and modifying the management of the Lower Mississippi River to support the 2017 Master Plan for the Louisiana coast. This paper will present the findings of one of the selected competitors: the Baird Team and their "Delta for All" approach. A key to success in the future management of the lower Mississippi River is the development of an integrated, holistic approach to management that recognizes the need to harness the full land/wetland building and restorative potential of the river at the same time as improving flood protection and navigation. Fundamentally the Baird solution recognized the underlying geomorphic challenges of the Delta: it receives three to four times less sediment from the Mississippi River than it did historically and sea level is rising two to three times faster than it did historically and is predicted to rise much faster in the future. The result will be a smaller delta in the future. Our approach seeks to harness as close to 100% of the land building potential of the river to make the smaller future delta as large as possible. This compares to the 2012 State Master Plan which would harness approximately 50% of the land-building potential. Our approach also recognizes that the further inland new distributary mouths and associated sub-deltas are located, the greater the delta building potential. Our approach builds with the river by creating and managing new river distributaries that are opened and closed every 50 years or so to build new sub-deltas within a defined sustainable delta footprint. By placing the last outlet somewhere in the vicinity of English Turn the lower Mississippi River would become a tidal channel. These two simple concepts of harnessing 100% of the river and placing the last outlet near English Turn result in immediate and significant benefits for flood protection and navigation. Through the

  4. Mazda kiintotyövaiheiden perustaminen : Delta Auto Oy

    OpenAIRE

    Schreck, Ville

    2012-01-01

    Täyden palvelun autoliikeketju Delta Auto myy ja huoltaa Kia-, Mitsubishi- ja Mazda-merkkisiä autoja paikkakuntakohtaisesti kahdessakymmenessäviidessä toimipisteessä. Opinnäytetyön tarkoituksena oli tehdä toimiva ratkaisu Mazdan työvaiheiden sekä työpakettien myyntiin Automaster-ohjelmistoon. Työvaiheet sekä ohjeajat tulevat käyttöön kaikkiin Delta Auton toimipisteisiin ympäri Suomea. Työn lähdemateriaalin sain Inchcape Motor Finland Oy:ltä, joka toimii Suomessa Mazdan maahantuojana. Tarve tä...

  5. CMOS sigma-delta converters practical design guide

    CERN Document Server

    De la Rosa, Jose M

    2013-01-01

    A comprehensive overview of Sigma-Delta Analog-to-Digital Converters (ADCs) and a practical guide to their design in nano-scale CMOS for optimal performance. This book presents a systematic and comprehensive compilation of sigma-delta converter operating principles, the new advances in architectures and circuits, design methodologies and practical considerations - going from system-level specifications to silicon integration, packaging and measurements, with emphasis on nanometer CMOS implementation. The book emphasizes practical design issues - from high-level behavioural modelling i

  6. Measurement of $\\Delta^{++}$(1232) production in hadronic Z decays

    CERN Document Server

    Abreu, P; Adye, T; Agasi, E; Ajinenko, I; Aleksan, Roy; Alekseev, G D; Allport, P P; Almehed, S; Alvsvaag, S J; Amaldi, Ugo; Amato, S; Andreazza, A; Andrieux, M L; Antilogus, P; Anykeyev, V B; Apel, W D; Arnoud, Y; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barão, F; Barate, R; Bardin, Dimitri Yuri; Barker, G J; Baroncelli, A; Bärring, O; Barrio, J A; Bartl, Walter; Bates, M J; Battaglia, Marco; Baubillier, M; Baudot, J; Becks, K H; Begalli, M; Beillière, P; Belokopytov, Yu A; Benvenuti, Alberto C; Berggren, M; Bertrand, D; Bianchi, F; Bigi, M; Bilenky, S M; Billoir, P; Bloch, D; Blume, M; Blyth, S; Bocci, V; Bolognese, T; Bonesini, M; Bonivento, W; Booth, P S L; Borisov, G; Bosio, C; Bosworth, S; Botner, O; Bouquet, B; Bourdarios, C; Bowcock, T J V; Bozzo, M; Branchini, P; Brand, K D; Brenke, T; Brenner, R A; Bricman, C; Brillault, L; Brown, R C A; Brückman, P; Brunet, J M; Bugge, L; Buran, T; Burgsmüller, T; Buschmann, P; Buys, A; Caccia, M; Calvi, M; Camacho-Rozas, A J; Camporesi, T; Canale, V; Canepa, M; Cankocak, K; Cao, F; Carena, F; Carrilho, P; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Cerrito, L; Chabaud, V; Charpentier, P; Chaussard, L; Chauveau, J; Checchia, P; Chelkov, G A; Chierici, R; Chliapnikov, P V; Chochula, P; Chorowicz, V; Cindro, V; Collins, P; Contreras, J L; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Crawley, H B; Crennell, D J; Crosetti, G; Cuevas-Maestro, J; Czellar, S; Dahl-Jensen, Erik; Dahm, J; D'Almagne, B; Dam, M; Damgaard, G; Daum, A; Dauncey, P D; Davenport, Martyn; Da Silva, W; Defoix, C; Della Ricca, G; Delpierre, P A; Demaria, N; De Angelis, A; De Boeck, H; de Boer, Wim; De Brabandere, S; De Clercq, C; La Vaissière, C de; De Lotto, B; De Min, A; De Paula, L S; De Saint-Jean, C; Dijkstra, H; Di Ciaccio, Lucia; Djama, F; Dolbeau, J; Dönszelmann, M; Doroba, K; Dracos, M; Drees, J; Drees, K A; Dris, M; Dufour, Y; Dupont, F; Edsall, D M; Ehret, R; Eigen, G; Ekelöf, T J C; Ekspong, Gösta; Elsing, M; Engel, J P; Ershaidat, N; Erzen, B; Espirito-Santo, M C; Falk, E; Fassouliotis, D; Feindt, Michael; Ferrer, A; Filippas-Tassos, A; Firestone, A; Fischer, P A; Föth, H; Fokitis, E; Fontanelli, F; Formenti, F; Franek, B J; Frenkiel, P; Fries, D E C; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Galloni, A; Gamba, D; Gandelman, M; García, C; García, J; Gaspar, C; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Gerber, J P; Gibbs, M; Gokieli, R; Golob, B; Gopal, Gian P; Gorn, L; Górski, M; Guz, Yu; Gracco, Valerio; Graziani, E; Grosdidier, G; Gunnarsson, P; Günther, M; Guy, J; Haedinger, U; Hahn, F; Hahn, M; Hahn, S; Hajduk, Z; Hallgren, A; Hamacher, K; Hao, W; Harris, F J; Hedberg, V; Henriques, R P; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Higón, E; Hilke, Hans Jürgen; Hill, T S; Holmgren, S O; Holt, P J; Holthuizen, D J; Houlden, M A; Hrubec, Josef; Huet, K; Hultqvist, K; Ioannou, P; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, G; Jarry, P; Jean-Marie, B; Johansson, E K; Jönsson, L B; Jönsson, P E; Joram, Christian; Juillot, P; Kaiser, M; Kapusta, F; Karlsson, M; Karvelas, E; Katsanevas, S; Katsoufis, E C; Keränen, R; Khomenko, B A; Khovanskii, N N; King, B J; Kjaer, N J; Klein, H; Klovning, A; Kluit, P M; Köhne, J H; Köne, B; Kokkinias, P; Koratzinos, M; Kostyukhin, V; Kourkoumelis, C; Kuznetsov, O; Kramer, P H; Krammer, Manfred; Kreuter, C; Królikowski, J; Kronkvist, I J; Krumshtein, Z; Krupinski, W; Kubinec, P; Kucewicz, W; Kurvinen, K L; Lacasta, C; Laktineh, I; Lamblot, S; Lamsa, J; Lanceri, L; Lane, D W; Langefeld, P; Lapin, V; Last, I; Laugier, J P; Lauhakangas, R; Leder, Gerhard; Ledroit, F; Lefébure, V; Legan, C K; Leitner, R; Lemoigne, Y; Lemonne, J; Lenzen, Georg; Lepeltier, V; Lesiak, T; Liko, D; Lindner, R; Lipniacka, A; Lippi, I; Lörstad, B; Lokajícek, M; Loken, J G; López, J M; López-Fernandez, A; López-Aguera, M A; Loukas, D; Lutz, P; Lyons, L; Maehlum, G; Maio, A; Malychev, V; Mandl, F; Marco, J; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Maron, T; Martínez-Rivero, C; Martínez-Vidal, F; Martí i García, S; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; Medbo, J; Meroni, C; Meyer, W T; Michelotto, M; Migliore, E; Mirabito, L; Mitaroff, Winfried A; Mjörnmark, U; Moa, T; Møller, R; Mönig, K; Monge, M R; Morettini, P; Müller, H; Mundim, L M; Murray, W J; Muryn, B; Myatt, Gerald; Naraghi, F; Navarria, Francesco Luigi; Navas, S; Negri, P; Némécek, S; Neumann, W; Neumeister, N; Nicolaidou, R; Nielsen, B S; Nieuwenhuizen, M; Nikolaenko, V; Niss, P; Nomerotski, A; Normand, Ainsley; Oberschulte-Beckmann, W; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Paganini, P; Paganoni, M; Pagès, P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Passeri, A; Pegoraro, M; Pernegger, H; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Phillips, H T; Piana, G; Pierre, F; Pimenta, M; Pindo, M; Plaszczynski, S; Podobrin, O; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Prest, M; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Reale, M; Rebecchi, P; Redaelli, N G; Regler, Meinhard; Reid, D; Renton, P B; Resvanis, L K; Richard, F; Richardson, J; Rídky, J; Rinaudo, G; Ripp, I; Romero, A; Roncagliolo, I; Ronchese, P; Roos, L; Rosenberg, E I; Rosso, E; Roudeau, Patrick; Rovelli, T; Rückstuhl, W; Ruhlmann-Kleider, V; Ruiz, A; Rybicki, K; Rybin, A; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sajot, G; Salt, J; Sánchez, J; Sannino, M; Schneider, H; Schyns, M A E; Sciolla, G; Scuri, F; Seager, P; Sedykh, Yu; Segar, A M; Seitz, A; Sekulin, R L; Shellard, R C; Siccama, I; Siegrist, P; Simonetti, S; Simonetto, F; Sissakian, A N; Sitár, B; Skaali, T B; Smadja, G; Smirnova, O G; Smith, G R; Sosnowski, R; Souza-Santos, D; Spassoff, Tz; Spiriti, E; Sponholz, P; Squarcia, S; Stanescu, C; Stapnes, Steinar; Stavitski, I; Stepaniak, K; Stichelbaut, F; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Szczekowski, M; Szeptycka, M; Tabarelli de Fatis, T; Tavernet, J P; Chikilev, O G; Tilquin, A; Timmermans, J; Tkatchev, L G; Todorov, T; Toet, D Z; Tomaradze, A G; Tomé, B; Tortora, L; Tranströmer, G; Treille, D; Trischuk, W; Tristram, G; Trombini, A; Troncon, C; Tsirou, A L; Turluer, M L; Tyapkin, I A; Tyndel, M; Tzamarias, S; Überschär, B; Ullaland, O; Uvarov, V; Valenti, G; Vallazza, E; Van der Velde, C; van Apeldoorn, G W; van Dam, P; Van Doninck, W K; Van Eldik, J; Vassilopoulos, N; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Vilanova, D; Vincent, P; Vitale, L; Vlasov, E; Vodopyanov, A S; Vrba, V; Wahlen, H; Walck, C; Waldner, F; Weierstall, M; Weilhammer, Peter; Wetherell, Alan M; Wicke, D; Wickens, J H; Wielers, M; Wilkinson, G R; Williams, W S C; Winter, M; Witek, M; Woschnagg, K; Yip, K; Yushchenko, O P; Zach, F; Zacharatou-Jarlskog, C; Zaitsev, A; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zhigunov, V P; Zimin, N I; Zito, M; Zontar, D; Zuberi, R; Zucchelli, G C; Zumerle, G

    1995-01-01

    A measurement of the \\Delta^{++}(1232) inclusive production in hadronic decays of the Z at LEP is presented, based on 1.3 million hadronic events collected~ by the DELPHI~ detector in the 1994 LEP running~ period. The DELPHI ring imaging Cherenkov counters are used for identifying hadrons. The average \\Delta^{++}(1232) multiplicity per hadronic event is 0.079 \\pm 0.015 which is more than a factor of two below the JETSET, HERWIG and UCLA model predictions. It agrees with a recently proposed universal mass dependence of particle production rates in e^{+}e^- annihilations.

  7. Water and nitrogen conditions affect the relationships of Delta13C and Delta18O to gas exchange and growth in durum wheat.

    Science.gov (United States)

    Cabrera-Bosquet, Llorenç; Molero, Gemma; Nogués, Salvador; Araus, José Luis

    2009-01-01

    Whereas the effects of water and nitrogen (N) on plant Delta(13)C have been reported previously, these factors have scarcely been studied for Delta(18)O. Here the combined effect of different water and N regimes on Delta(13)C, Delta(18)O, gas exchange, water-use efficiency (WUE), and growth of four genotypes of durum wheat [Triticum turgidum L. ssp. durum (Desf.) Husn.] cultured in pots was studied. Water and N supply significantly increased plant growth. However, a reduction in water supply did not lead to a significant decrease in gas exchange parameters, and consequently Delta(13)C was only slightly modified by water input. Conversely, N fertilizer significantly decreased Delta(13)C. On the other hand, water supply decreased Delta(18)O values, whereas N did not affect this parameter. Delta(18)O variation was mainly determined by the amount of transpired water throughout plant growth (T(cum)), whereas Delta(13)C variation was explained in part by a combination of leaf N and stomatal conductance (g(s)). Even though the four genotypes showed significant differences in cumulative transpiration rates and biomass, this was not translated into significant differences in Delta(18)O(s). However, genotypic differences in Delta(13)C were observed. Moreover, approximately 80% of the variation in biomass across growing conditions and genotypes was explained by a combination of both isotopes, with Delta(18)O alone accounting for approximately 50%. This illustrates the usefulness of combining Delta(18)O and Delta(13)C in order to assess differences in plant growth and total transpiration, and also to provide a time-integrated record of the photosynthetic and evaporative performance of the plant during the course of crop growth.

  8. Riders on the storm: selective tidal movements facilitate the spawning migration of threatened delta smelt in the San Francisco Estuary

    Science.gov (United States)

    Bennett, W.A.; Burau, Jon R.

    2015-01-01

    Migration strategies in estuarine fishes typically include behavioral adaptations for reducing energetic costs and mortality during travel to optimize reproductive success. The influence of tidal currents and water turbidity on individual movement behavior were investigated during the spawning migration of the threatened delta smelt, Hypomesus transpacificus, in the northern San Francisco Estuary, California, USA. Water current velocities and turbidity levels were measured concurrently with delta smelt occurrence at sites in the lower Sacramento River and San Joaquin River as turbidity increased due to first-flush winter rainstorms in January and December 2010. The presence/absence of fish at the shoal-channel interface and near the shoreline was quantified hourly over complete tidal cycles. Delta smelt were caught consistently at the shoal-channel interface during flood tides and near the shoreline during ebb tides in the turbid Sacramento River, but were rare in the clearer San Joaquin River. The apparent selective tidal movements by delta smelt would facilitate either maintaining position or moving upriver on flood tides, and minimizing advection down-estuary on ebb tides. These movements also may reflect responses to lateral gradients in water turbidity created by temporal lags in tidal velocities between the near-shore and mid-channel habitats. This migration strategy can minimize the energy spent swimming against strong river and tidal currents, as well as predation risks by remaining in turbid water. Selection pressure on individuals to remain in turbid water may underlie population-level observations suggesting that turbidity is a key habitat feature and cue initiating the delta smelt spawning migration.

  9. Beyond the Dams: Linking Rural Smallholder Soil and Water Management Practices in Tropical Deltas to Sea Level Rise Vulnerability

    Science.gov (United States)

    Rogers, K. G.; Syvitski, J. P.; Brondizio, E. S.

    2014-12-01

    The increased vulnerability of deltaic communities to coastal flooding as a result of upstream engineering has been acknowledged for decades. What has received less attention is the sensitivity of deltas to the interactions of river basin modifications and cultivation and irrigation in their coastal regions, particularly in tropical deltas. Embanking, tilling, and crop or stock choice all affect the movement of sediment and water on deltas. Combined with reduced river and sediment discharge, soil and water management practices in coastal areas may in fact exacerbate the risk of tidal flooding, erosion of arable land, and salinization of soils and groundwater associated with sea level rise. Thus exists a cruel irony to smallholder subsistence farmers whose priorities are food, water and economic security, rather than sustainability of the regional environment. Such issues challenge disciplinary approaches and require integrated social-biophysical models able to understand and diagnose these complex relationships. The complementary Institutional Analysis and Development and SocioEcological Systems frameworks are applied to the southwestern Bengal Delta (Bangladesh). The method helps to define the relevant social and physical units operating on the common pool of environmental resources, those of climate, water and sediment. The conceptual frameworks are designed to inform development of a nested geospatial analysis and a dynamic coupled model to identify the social-biophysical feedbacks associated with smallholder soil and water management practices, coastal dynamics, and climate vulnerability in rural Bangladesh. Our presentation will discuss components of the conceptual frameworks and will introduce a bi-directional pilot study designed for obtaining and disseminating information about environmental change to farmers in southwest Bangladesh with potential application to rural farming communities in other tropical deltas.

  10. Sinking Deltas are Trapped in a Dual Lock-in of Technology and Institutions: Exploring the Trap and 3 Steps to Break Out.

    Science.gov (United States)

    Seijger, C.; Janssen, S.; Erkens, G.

    2017-12-01

    Although the topic of sinking deltas has been put convincingly in the academic spotlight, we consider it highly unlikely that neither subsidence nor the resulting damage will reduce in the near future as subsiding deltas are trapped in a dual lock-in of technology and institutions. People, and the engineering technologies they have applied, are root causes for sinking deltas worldwide. To serve growing economics and populations, conventional water management strategies have increasingly been implemented (more dikes, dams, groundwater pumping, land reclamation) that cause, exacerbate, or facilitate subsidence. The increasing implementation of these strategies enlarged the power of those implementing it: in the US, an increase in dam and levee construction projects meant an increase in power of the US Army Corps of Engineers; in groundwater irrigation, rich farmers have the capacity to monopolise groundwater over poorer farmers; and key beneficiaries of more hydropower projects in China are the hydropower companies. Nine factors for the lock-in are introduced and illustrated for delta regions in Asia, Europe, and the US. The lock-in factors describe financial, social and technological reasons why certain institutions and technologies become dominant over alternatives. Sinking deltas like the Mekong or Mississippi Delta are thus trapped in a dual lock-in and on a self-reinforcing path of delta development with increasing areas of deltas sinking below sea level. Due to the persistency of these developments, pathways for change are needed. We propose three steps to break the dual lock-in (see Figure): (1) getting to know the lock-in through transdisciplinary research (2 years) (2) temporarily bypass it through experiments in technology and institutions (10 years) (3) constitute a new, more sustainable lock-in by mainstreaming shifts in technology and institutions (10-50 years) The dual lock-in concept offers a novel integrated understanding on sinking deltas

  11. Diet, Prey Selection, and Body Condition of Age-0 Delta Smelt, Hypomesus transpacificus, in the Upper San Francisco Estuary

    Directory of Open Access Journals (Sweden)

    Steven B. Slater

    2014-09-01

    Full Text Available Steven B. Slater and Randall D. Baxterdoi: http://dx.doi.org/10.15447/sfews.2014v12iss3art1The Delta Smelt, an endangered fish, has suffered a long-term decline in abundance, believed to result from, in part, to changes in the pelagic food web of the upper San Francisco Estuary. To investigate the current role of food as a factor in Delta Smelt well-being, we developed reference criteria for gut fullness and body condition based on allometric growth. We then examined monthly diet, prey selectivity, and gut fullness of larvae and juvenile Delta Smelt collected April through September in 2005 and 2006 for evidence of feeding difficulties leading to reduced body condition. Calanoid copepods Eurytemora affinis and Pseudodiaptomus forbesi remained major food items during spring and from early summer through fall, respectively. Other much larger copepods and macroinvertebrates contributed in lesser numbers to the diet of older juvenile fish from mid-summer through fall. In fall, juvenile Delta Smelt periodically relied heavily on very small prey and prey potentially associated with demersal habitat, suggesting typical pelagic food items were in short supply. We found a strong positive selection for E. affinis and P. forbesi, neutral to negative selection for evasive calanoid Sinocalanus doerrii, and neutral to negative selection for the small cyclopoid copepod Limnoithona tetraspina and copepod nauplii, which were consumed only when extremely numerous in the environment. Feeding incidence was significantly higher in 2006, but among successfully feeding fish we found no between year difference in gut fullness. However, we did detect differences in fullness across months in both years. We found no difference in body condition of Delta Smelt between years yet our sample sizes were low in September when Delta Smelt reverted to feeding on very small organisms and fullness declined, so the longer-term effect remains unknown. Our findings suggest that: Delta

  12. The Mangroves of the Zambezi Delta: Increase in Extent Observed via Satellite from 1994 to 2013

    Directory of Open Access Journals (Sweden)

    Aurélie C. Shapiro

    2015-12-01

    Full Text Available Mangroves are recognized for their valued ecosystem services provision while having the highest carbon density among forested ecosystems. Yet they are increasingly threatened by deforestation, conversion to agriculture and development, reducing the benefits they provide for local livelihoods, coastal protection and climate change mitigation. Accordingly, accurate estimates of mangrove area and change are fundamental for developing strategies for sustainable use, conservation and Reducing Emissions from Deforestation and Degradation (REDD+. The Zambezi River Delta in Mozambique contains one of the largest mangrove forests in Africa, and deforestation has been reported to be substantial, however these estimates vary widely. We used Landsat imagery from 1994, 2000 and 2013, to estimate a total current mangrove area of 37,034 ha, which is a net increase of 3723 ha over 19 years. The land cover change assessment was also used to provide perspective on ecosystem carbon stocks, showing that the Zambezi Delta mangrove ecosystem acts as a large carbon sink. Our findings reinforce the importance of conducting land cover change assessments using coherent data and analytical models, coupled with field validation. Broader application of our approach could help quantify the rates of natural change from erosion and land aggradation contrasted with anthropogenic causes.

  13. Metabolites of the 1',2'-dimethylheptyl analogue of delta-8-tetrahydrocannabinol in the mouse and their identification by gas chromatography/mass spectrometry.

    Science.gov (United States)

    Harvey, D J; Brown, N K

    1990-10-01

    Metabolism of the 1,2-dimethylheptyl analogue of delta-8-tetrahydrocannabinol (delta-8-DMHP) was studied in vitro using mouse hepatic microsomes and in vivo in mouse liver. Metabolites were extracted with ethyl acetate, concentrated by chromatography on Sephadex LH-20 and examined by low-resolution mass spectrometry as trimethylsilyl (TMS), (2H9)TMS and methyl ester/TMS derivatives. Reduction of metabolites with lithium aluminium deuteride also provided structural information. The electron-impact-induced mass spectrum of the TMS derivative of DMHP differed from that of its unbranched side-chain analogues in that prominent ions were produced by fragmentation of the side-chain at the expense of the retro-Diels-Alder fragmentation that was prominent in the spectra of the latter compounds. This, however, was found to reduce the relative abundance of ions diagnostic of side-chain hydroxy substitution in the spectra of the metabolites. In vitro, the only significant metabolite was 11-hydroxy-delta-8-DMHP. This is in contrast with metabolism of the corresponding delta-8-tetrahydrocannabinol (delta-8-THC, n-C5-side-chain) where a number of other monohydroxy metabolites are produced. Fifteen metabolites were found in vivo, of which nine were identified. Mass spectral information was not sufficient to determine the position of one of the hydroxy groups in the other six metabolites. The major site of hydroxylation was at C-11 and the resulting hydroxy metabolite was oxidized to delta-8-DMHP-11-oic acid. In this respect metabolism paralleled that of delta-8-THC. Dihydroxylation of the double bond also occurred, presumably via the epoxide.(ABSTRACT TRUNCATED AT 250 WORDS)

  14. Elafibranor, an Agonist of the Peroxisome Proliferator-Activated Receptor-alpha and -delta, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

    NARCIS (Netherlands)

    Ratziu, V.; Harrison, S.A.; Francque, S.; Bedossa, P.; Lehert, P.; Serfaty, L.; Romero-Gomez, M.; Boursier, J.; Abdelmalek, M.; Caldwell, S.; Drenth, J.P.; Anstee, Q.M.; Hum, D.; Hanf, R.; Roudot, A.; Megnien, S.; Staels, B.; Sanyal, A.

    2016-01-01

    BACKGROUND & AIMS: Elafibranor is an agonist of the peroxisome proliferator-activated receptor-alpha and peroxisome proliferator-activated receptor-delta. Elafibranor improves insulin sensitivity, glucose homeostasis, and lipid metabolism and reduces inflammation. We assessed the safety and efficacy

  15. Polarized antiquark flavor asymmetry DELTA anti u(x)-DELTA anti d(x) and the pion cloud

    CERN Document Server

    Fries, R J; Weiss, C

    2003-01-01

    The flavor asymmetry of the unpolarized antiquark distributions in the proton, anti u(x)- anti d(x)0. Using a simple chiral linear sigma model as an example, we demonstrate that in the meson cloud picture a large positive DELTA anti u(x)-DELTA anti d(x) can be obtained from pi-sigma interference contributions. This calls into question previous estimates based on rho-meson contributions alone, and indicates how the results of the meson cloud picture may be reconciled with those of quark-based models. (orig.)

  16. Effects of the proposed California WaterFix North Delta Diversion on flow reversals and entrainment of juvenile Chinook salmon (Oncorhynchus tshawytscha) into Georgiana Slough and the Delta Cross Channel, northern California

    Science.gov (United States)

    Perry, Russell W.; Romine, Jason G.; Pope, Adam C.; Evans, Scott D.

    2018-02-27

    The California Department of Water Resources and Bureau of Reclamation propose new water intake facilities on the Sacramento River in northern California that would convey some of the water for export to areas south of the Sacramento-San Joaquin River Delta (hereinafter referred to as the Delta) through tunnels rather than through the Delta. The collection of water intakes, tunnels, pumping facilities, associated structures, and proposed operations are collectively referred to as California WaterFix. The water intake facilities, hereinafter referred to as the North Delta Diversion (NDD), are proposed to be located on the Sacramento River downstream of the city of Sacramento and upstream of the first major river junction where Sutter Slough branches from the Sacramento River. The NDD can divert a maximum discharge of 9,000 cubic feet per second (ft3/s) from the Sacramento River, which reduces the amount of Sacramento River inflow into the Delta.In this report, we conducted three analyses to investigate the effect of the NDD and its proposed operation on entrainment of juvenile Chinook salmon (Oncorhynchus tshawytscha) into Georgiana Slough and the Delta Cross Channel (DCC). Fish that enter the interior Delta (the network of channels to the south of the Sacramento River) through Georgiana Slough and the DCC survive at lower rates than fish that use other migration routes (Sacramento River, Sutter Slough, and Steamboat Slough). Therefore, fisheries managers were concerned about the extent to which operation of the NDD would increase the proportion of the population entering the interior Delta, which, all else being equal, would lower overall survival through the Delta by increasing the fraction of the population subject to lower survival rates. Operation of the NDD would reduce flow in the Sacramento River, which has the potential to increase the magnitude and duration of reverse flows of the Sacramento River downstream of Georgiana Slough.In the first analysis, we

  17. 77 FR 61592 - Arkansas Electric Cooperative Corporation; Mississippi Delta Energy Agency; Clarksdale Public...

    Science.gov (United States)

    2012-10-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-110-000] Arkansas Electric Cooperative Corporation; Mississippi Delta Energy Agency; Clarksdale Public Utilities Commission.... 825(h), Arkansas Electric Cooperative Corporation, Mississippi Delta Energy Agency, and its two...

  18. Profitability and constraints in the marketing of poultry birds in Delta ...

    African Journals Online (AJOL)

    Profitability and constraints in the marketing of poultry birds in Delta central agricultural zone, Delta state, Nigeria. ... Randomly selected 54 poultry bird marketers were surveyed in 5 major markets. ... EMAIL FULL TEXT EMAIL FULL TEXT

  19. Crude Oil, a Blessing and Impediment in Niger Delta Polity: Tanure ...

    African Journals Online (AJOL)

    Journal Home > Special Edition 2011 > ... Oil has constituted a physical problem to Delta State and Nigeria as a whole. ... impediment in Delta of Nigeria; Economic growth constraints, socio-political problems and Neo-colonialism; and finally,

  20. Application in Down-hole Milling Operations In Niger Delta.

    African Journals Online (AJOL)

    ENGINEERS

    export terminals, 275 flow stations, 10 gas plants, 3 refineries and a massive natural ..... clear of the Niger Delta', adding that, 'The Chinese government by investing in stolen .... Development Agency (SMEDAN); to help boost the growth of both countries' ..... “The Rule of Oil: Petro-Politics and the Anatomy of an Insurgency”.

  1. Gambiense Sleeping Sickness In The Abraka Region Of Delta State ...

    African Journals Online (AJOL)

    Gambiense Sleeping Sickness In The Abraka Region Of Delta State, Nigeria: Passive Case Detection (Pcd) At The Baptist Medical Centre (BMC) Eku 1999 – 2004. ... The highest prevalence of infection was among patients aged between 26-35 years with 35.6% infection rate, 23.3 percent was recorded among those aged ...

  2. year Review of Patients on DOTS in Delta State, Nigeria

    African Journals Online (AJOL)

    UNIBEN

    1Department of Community Medicine, Delta State University Teaching ... Therapy Short-course (DOTS), DOTS plus, and the Stop TB Strategy. ... Methods: In this descriptive records review of years 2011-2015, existing data ... Treatment success rate improved from 68.3% in ..... exploration and social interventions to curb it.

  3. Delta-gamma-theta Hedging of Crude Oil Asian Options

    Directory of Open Access Journals (Sweden)

    Juraj Hruška

    2015-01-01

    Full Text Available Since Black-Scholes formula was derived, many methods have been suggested for vanilla as well as exotic options pricing. More of investing and hedging strategies have been developed based on these pricing models. Goal of this paper is to derive delta-gamma-theta hedging strategy for Asian options and compere its efficiency with gamma-delta-theta hedging combined with predictive model. Fixed strike Asian options are type of exotic options, whose special feature is that payoff is calculated from the difference of average market price and strike price for call options and vice versa for the put options. Methods of stochastic analysis are used to determine deltas, gammas and thetas of Asian options. Asian options are cheaper than vanilla options and therefore they are more suitable for precise portfolio creation. On the other hand their deltas are also smaller as well as profits. That means that they are also less risky and more suitable for hedging. Results, conducted on chosen commodity, confirm better feasibility of Asian options compering with vanilla options in sense of gamma hedging.

  4. Assessing School Facilities in Public Secondary Schools in Delta ...

    African Journals Online (AJOL)

    This study investigated school facilitates in public secondary schools in Delta State, Nigeria. The purpose of the study was to find out the state of the facilities, the types of maintenance carried out on the facilities by school administrators, the factors encouraging school facilities depreciation and the roles of school ...

  5. Monte Carlo simulations of the stability of delta-Pu

    DEFF Research Database (Denmark)

    Landa, A.; Soderlind, P.; Ruban, Andrei

    2003-01-01

    The transition temperature (T-c) for delta-Pu has been calculated for the first time. A Monte Carlo method is employed for this purpose and the effective cluster interactions are obtained from first-principles calculations incorporated with the Connolly-Williams and generalized perturbation methods...

  6. Evolution of the Niger Delta, present dynamics and the future ...

    African Journals Online (AJOL)

    Evolution of the Niger Delta is closely linked to the geodynamics related to the separation of the African and South American continents and the tectonics of the formation of the Benue Trough. Tectonic activities, climate and eustasy are the major factors responsible for transgression and regression through the entrant point ...

  7. Validity and reliability of the Delta Healthy Eating Attitudes Scale

    Science.gov (United States)

    The objective of this study was to evaluate psychometric properties of an instrument developed to measure psychosocial factors related to the Dietary Guidelines for Americans for a nutrition intervention in the Lower Mississippi Delta (LMD). Social Cognitive Theory constructs social support (SS), s...

  8. 75 FR 56094 - Delta-Mendota Canal Intertie Project

    Science.gov (United States)

    2010-09-15

    ... Project AGENCY: Western Area Power Administration, DOE. ACTION: Notice of Record of Decision and... maintain a new 69-kilovolt (kV) transmission line and fiber optic cable for delivery of project use power...) Delta-Mendota Canal (DMC)/California Aqueduct Intertie (Intertie) project. The Intertie, including the...

  9. Eating Habits of the Elderly in Asaba, Delta State, Nigeria ...

    African Journals Online (AJOL)

    Objectives: The study was undertaken to describe the eating habits of literate elderly in Asaba, urban city in Delta State of Nigeria. Methods: A total of 176 elderly male (62.5%) and female (37.5%) aged 50years and above who attended Medical Lectures of the Ebreme foundation for the elderly were enrolled in this study.

  10. Morphodynamics of the Manyema Tidal Delta at Kunduchi, Tanzania

    African Journals Online (AJOL)

    Keywords: Morphodynamics, Kunduchi, Manyema, shoreline change, tidal creek, tidal delta. Abstract—The prevailing northward longshore drift of beach sand on the northern part of Msasani Bay, north of Dar es Salaam, is interrupted at Kunduchi by the tidal flushing of ... Western Indian Ocean J. Mar. Sci. Vol. 11, No. 2, pp.

  11. Ibani (Niger Delta) Traditional Religion and Social Morality | Jaja ...

    African Journals Online (AJOL)

    The Ibani is of the Ijo extraction in the Niger Delta of Nigeria. The belief in a Supreme Being called Tamuno but also on multitude of deities because of the environment in which they live. They believe that these deities perform social functions that stabilize society. Ibani cosmology revolve round the tripod – God, deities and ...

  12. Interacting boson model with surface delta interaction between nucleons

    International Nuclear Information System (INIS)

    Druce, C.; Moszkowski, S.A.

    1984-01-01

    The surface delta interaction is used as an effective nucleon-nucleon interaction to investigate the structure and interaction of the bosons in the interacting boson model. The authors have obtained analytical expressions for the coefficients of a multipole expansion of the neutron-boson proton-boson interaction for the case of degenerate orbits

  13. Ethnic Minority Problems in the Niger Delta | Quaker-Dokubo ...

    African Journals Online (AJOL)

    As a conceptual background typical types of minorities and typical sources of minority conflict are outlined. A historical overview is given of the problems Niger Delta minorities have been experiencing. Their grievances and demands are highlighted, and the responses of different Nigerian governments are discussed.

  14. Perceptions, Attitudes and Practices on Schistosomiasis in Delta ...

    African Journals Online (AJOL)

    The main objective of the study reported here was to assess the knowledge, attitude/perception and practices of the people in Oshimili South and Ndokwa Northeast Local Government Areas of Delta State in Nigeria. A cross-sectional study of 400 randomly selected persons aged ≥15 years was undertaken using a uniform ...

  15. Final Narrative Report on Nursing Ethics at Delta College.

    Science.gov (United States)

    Pfeiffer, Raymond S.

    This four-part report describes a project undertaken by Delta College to implement two required bioethics courses for nursing students: an introductory course in ethical theories and an advanced course in applications of these theories in nursing. After Part I relates how funding for the project was secured and used, Part II delineates the…

  16. The Localizing Value Of Focal Delta Slowing In Temporal Lobe ...

    African Journals Online (AJOL)

    Slow wave EEG had a higher marginal probability than neuropsychological assessment of predicting the focus, and was equally effective as other investigative methods. Conclusion These results suggest that focal temporal delta slowing is useful in the localization of epileptogenic foci. There was no discordance with the ...

  17. Practical Design of Delta-Sigma Multiple Description Audio Coding

    DEFF Research Database (Denmark)

    Leegaard, Jack Højholt; Østergaard, Jan; Jensen, Søren Holdt

    2014-01-01

    It was recently shown that delta-sigma quantization (DSQ) can be used for optimal multiple description (MD) coding of Gaussian sources. The DSQ scheme combined oversampling, prediction, and noise-shaping in order to trade off side distortion for central distortion in MD coding. It was shown that ...

  18. Evaluation Of Delta State E-Government Website | Chete ...

    African Journals Online (AJOL)

    The study evaluates Delta state government website by adopting the method used since 2001 in evaluating national government websites. The questionnaire and web survey techniques were adopted for this study. The data from the questionnaire was analyzed using statistical package for social sciences (SPSS) and the ...

  19. training needs of school inspectors for quality instruction in delta

    African Journals Online (AJOL)

    www.globaljournalseries.com; Info@globaljournalseries.com ... 29. Jude Ekuevugbe Omorigho, Post Primary Education Board, Asaba, Delta State, Nigeria. ... Effective communication training for school .... Decision. Inspectors. 3.12. 0.25. Important. Headmasters. 2.96. 0.11. Table 3, shows that the individual means.

  20. Atlantic humpback dolphins Sousa teuszii in the Saloum Delta ...

    African Journals Online (AJOL)

    During October and November 2015, the first systematic survey of Sousa teuszii was carried out in the Saloum Delta (Senegal, West Africa), comprising 1 617.5 km of boat-based survey coverage. Thirty sightings were recorded in the Saloum and Diomboss rivers, and along the southern coastline. Dolphins were also ...

  1. Environmental Degradation in Oil Producing Areas of Niger Delta ...

    African Journals Online (AJOL)

    Due to oil exploration and other human activities in the Niger Delta region, there is evidence of environmental degradation all over the area (Oronto, 1998). Environmental degradation is occasioned by consistent flow of industrial waste, oil spills, gas flares, fire disaster, acid rain, flooding erosion, etc., which has led to the ...

  2. Acid Rain in Niger Delta Region: Implication on Water Resources ...

    African Journals Online (AJOL)

    This research focused on the effect of acid rain on the water quality of the Niger Delta region of Nigeria. Three hundred water samples were collected: 100 water samples from rain, 100 from open wells and 100 from rivers. The water samples were analysed using the paired t-test and multiple correlation analysis to ascertain ...

  3. Adolescent Sexual and Reproductive Health in the Niger Delta ...

    African Journals Online (AJOL)

    There has been an increasing awareness of the need to pay special focus on the adolescent and their sexual and reproductive health. This article reviews the sexual and reproductive health of adolescents in the Niger Delta region (NDR) of Nigeria. The objective is to bring to focus these important issues in the region.

  4. Isospin-breaking nuclear forces with delta degrees of freedom

    International Nuclear Information System (INIS)

    Epelbaum, E.

    2008-01-01

    The leading contributions to the isospin-violating (IV) two- and three-nucleon forces in effective field theory with explicit delta degrees of freedom are discussed. Presented at the 20th Few-Body Conference, Pisa, Italy, 10-14 September 2007. (author)

  5. Experience on tangent delta norms adopted for repaired generator

    International Nuclear Information System (INIS)

    Misra, N.N.; Sood, D.K.

    2005-01-01

    The repair techniques of the generators are very crucial for avoiding prolonged forced outages. The crucial decisions based on sound knowledge and judgement becomes essential in many cases. The unit under discussions had failed on account of flash over in the Exciter end overhang windings. The failure resulted in damaged to the stator bars as well as generator core. The damaged end packets of the stator core were replaced at site. The total winding bars were removed from stator core and damaged bars were replaced with new bars. The rest of the bars were tested for tangent delta tests for reuse. Acceptance norms of 0.6% tip up from 0.2pu to 0.6pu of rated stator voltage were adopted. Some of the bars outside the acceptable limits of tangent delta were shifted close to neutral so that the standard norms of tan delta are met. This was felt necessary because lead-time for procurement of new bars was more than six months. The above-adopted norms for tangent delta will be of much use for the operating utilities. The unit under discussions was of 67.5 MW operating at 50 Hz, 0.85 pf lag and had logged 66160.46 operating hours before failure. (author)

  6. Use of Cybercafe's Services by Households in Delta State, Nigeria ...

    African Journals Online (AJOL)

    Cyber cafés' provide important public services. They provide access to wide range of information through the internet via the computer. The study is centered on the use of cyber cafés by households in Delta State. Services provided by the cyber café's were identified. The study revealed that Household with children under ...

  7. Dermal absorption of the insecticide lindane (1 delta, 2 delta, 3 beta, 4 delta, 5 delta, 6 beta-hexachlorocyclohexane) in rats and rhesus monkeys: Effect of anatomical site

    International Nuclear Information System (INIS)

    Moody, R.P.; Ritter, L.

    1989-01-01

    Dermal absorption of the insecticide lindane (1 delta, 2 delta, 3 beta, 4 delta, 5 delta, 6 beta-hexachlorocyclohexane) was determined in rats and rhesus monkeys. Lindane is in widespread use as a 1% cream or lotion scabicide formulation and as a 1% miticide shampoo for body lice control in humans. Results obtained following our in vivo dermal absorption procedure demonstrated that 18 +/- 4.1%, 34 +/- 5.2%, and 54 +/- 26.3% of the applied dose was absorbed following topical applications at a rate of 1.5 micrograms/cm2 (6.2 micrograms/100 microliters of acetone) of the 14C-labeled pesticide to 4.2-cm2 regions of the forearm (n = 8), forehead (n = 7), and palm (n = 4) of rhesus monkeys, respectively. Dose sites were washed with soapy water 24 h posttreatment. Comparative studies in rats (n = 5) dosed middorsally demonstrated 31 +/- 9.5% absorption. Statistical analysis of the 14C excretion kinetics demonstrated slower clearance of lindane from rats than monkey forearm, forehead, or palm. Intramuscular (im) injections of 14C-lindane gave 52 +/- 7.1% recovery in monkey (n = 8) and 64 +/- 5.9% in rats (n = 5), suggesting body storage of this lipophilic chemical

  8. Characterization of middle Eocene tide-influenced delta: a study ...

    Indian Academy of Sciences (India)

    42

    Running Title: Eocene tide-influenced delta in South Cambay Basin. Manuscript. Click here to view linked References. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10 .... systematic documentation of the facies types to establish the depositional environment of the .... Hazad Member consists of a number of sandstone units separated by intervening ...

  9. Schrodinger operators with delta-interactions supported on conical surfaces

    Czech Academy of Sciences Publication Activity Database

    Behrndt, J.; Exner, Pavel; Lotoreichik, V.

    2014-01-01

    Roč. 47, č. 35 (2014), s. 355202 ISSN 1751-8113 R&D Projects: GA ČR(CZ) GA14-06818S; GA MŠk 7AMB13AT010 Institutional support: RVO:61389005 Keywords : Schrödinger operator * delta potential * infinite discrete spectrum Subject RIV: BE - Theoretical Physics Impact factor: 1.583, year: 2014

  10. Amnesty in the Niger Delta: vertical movement towards self ...

    African Journals Online (AJOL)

    ... promises of infrastructure development in the region and direct payments of oil revenues to host-communities. This paper seeks to examine the recent developments vis-à-vis the government's amnesty initiative to determine if this policy has bridged the gap in the longstanding selfdetermination demands of the Niger Delta ...

  11. Childhood nutrition in the Mississippi Delta: challenges and opportunities.

    Science.gov (United States)

    Gray, Virginia B; Byrd, Sylvia H; Fountain, Brent J; Rader, Nicole E; Frugé, Andrew D

    2016-12-01

    Childhood obesity in the USA has more than tripled in the last three decades, and the prevalence is higher in the Mississippi Delta. Insight into the social, cultural and environmental factors that influence inequity can inform efforts to mediate health disparities. Focus groups (n = 12) among parents/guardians of elementary school children (n = 44) and teachers (n = 59) in the Mississippi Delta were used to investigate barriers and facilitators of healthy eating. Transcriptions were analyzed for themes. A strong preference for junk food among children and the pervasiveness of junk foods in schools and communities were cited as barriers to healthy eating. Potential facilitators of healthy eating included desire to avoid chronic disease, effort to limit junk food consumption and school support. Despite support for efforts to improve nutrition in the Delta, participants voiced a sense of inevitability related to children's consumption of unhealthy foods. This study suggests that parents and teachers express concern related to eating habits of children, yet they experience barriers to healthy eating which contribute to a sense of disempowerment. Improving health in the Mississippi Delta requires comprehensive strategies that offer its citizens a sense of agency. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  12. Drones on the delta | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2016-11-25

    Nov 25, 2016 ... Ghana's Volta River delta is an area vulnerable to climate change, with rising seas and increasingly powerful storms driving flooding and erosion, leaving authorities there questioning whether the best response involves solutions such as sea walls or migration. A group of researchers is using drones to ...

  13. aranthus cruentus L) in the Niger Delta Region of Nigeria

    African Journals Online (AJOL)

    ABSTRACT. Experiments were conducted in 1987 and 1988 to study the response of Amaranthus cruentus L. to flooded soils at Ekpoma, situated in-the Niger Delta Region of Nigeria. The objective of this study was to examine the effect of flooding on yield of A. Céiieiìtus. The study revealed that the negative response of the ...

  14. The Economic Dimensions of the Niger Delta Ethnic Conflicts ...

    African Journals Online (AJOL)

    This paper presents a descriptive analysis of the remote and immediate causes of the armed ethnic conflicts in the Niger Delta in Nigeria and attempts to proffer a strategic approach rather than the use of brute force in managing the conflicts. The study revealed that the underlying cause of the conflict is the prolonged ...

  15. A Signal-Interleaving Complex Bandpass Sigma-Delta Converter

    DEFF Research Database (Denmark)

    Wad, Paul Emmanuel

    1997-01-01

    Complex or quadrature Sigma-Delta converters operate on complex signals, i.e. signals consisting of a real and an imaginary component, whereas conventional converters operate only on real signals. The advantage of complex signal processing in the discrete-time domain is that the entire sampling...

  16. Towards an Ethics of the Environment in the Niger Delta

    African Journals Online (AJOL)

    FIRST LADY

    and the responsibility for both human and non-human components of nature are indeed wholly ... intend to do in this work therefore is to evolve an ethics of the Niger Delta environment which ... African Research Review Vol. 4(3a) July, 2010.

  17. Fundraising processes in Nigerian Academic Libraries: The Delta ...

    African Journals Online (AJOL)

    The paper examines fundraising processes in academic libraries in Delta State. The aim is to find out the extent to which fund raising processes can help in solving funding problems in academic libraries. The descriptive research method was employed. Eleven academic libraries in Delt a State were used in this study, that ...

  18. 2009-2010 USACE Vicksburg District Lidar: Mississippi River Delta

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — LiDAR collected at 1.0 points per square meter (1.0m GSD) for the entire portion of the Mississippi River Delta in the Vicksburg District. This area was flown during...

  19. Hepatitis delta in HIV-infected individuals in Europe

    DEFF Research Database (Denmark)

    Soriano, Vincent; Grint, Daniel; Monforte, Antonellad'arminio

    2011-01-01

    BACKGROUND:: Hepatitis delta virus (HDV) infection results in the most aggressive form of chronic viral hepatitis. There is scarce information about the prevalence, epidemiology, virological profile and natural historyof hepatitis delta in HIV patients. METHODS:: From 16,597 HIV patients enrolled......-RNA was quantified using a real-time PCR method. RESULTS:: A total of 61/422 HBsAg+ carriers were anti-HDV+ (prevalence: 14.5%). Hepatitis delta predominated in intravenous drug users and for this reason in South and/or East Europe. Serum HDV-RNA was detectable in 87% of tested anti-HDV+ patients, with a median...... titer of 1.76x10¿copies/ml. Overall, delta hepatitis patients showed lower serum HBV-DNA than the rest of HBsAg+ carriers, although the inhibitory effect of HDV on HBV replication was not recognized in HBV genotype D patients.Whereas HDV was not associated with progression to AIDS, it significantly...

  20. Comparative Noise Pollution Study Of Some Major Towns In Delta ...

    African Journals Online (AJOL)

    Comparative noise pollution studies have been carried out in some major towns in Delta State, Nigeria using a PIONneer 65 noise dosimeter. The noise measurements were taken at ten points within each of the towns at an interval of 30 minutes during the peak period of the day and at the cool of the night. The results ...

  1. Delta Healthy Sprouts: Participants' Diet and Food Environment at Baseline

    Science.gov (United States)

    Local food environments influence the nutrition and health of area residents. This baseline analysis focuses on the food environments of women who participated in the Delta Healthy Sprouts project, a randomized, controlled, comparative trial designed to test the efficacy of two Maternal, Infant, an...

  2. The Problem with the Delta Cost Project Database

    Science.gov (United States)

    Jaquette, Ozan; Parra, Edna

    2016-01-01

    The Integrated Postsecondary Education System (IPEDS) collects data on Title IV institutions. The Delta Cost Project (DCP) integrated data from multiple IPEDS survey components into a public-use longitudinal dataset. The DCP Database was the basis for dozens of journal articles and a series of influential policy reports. Unfortunately, a flaw in…

  3. Nonlinearities in SC Delta-Sigma A/D Converters

    DEFF Research Database (Denmark)

    Steensgaard-Madsen, Jesper

    1998-01-01

    The effects of using nonlinear low-gain opamps in switched-capacitor delta-sigma modulators are analyzed. Using unconventional topologies, the state variables are made essentially uncorrelated with the input signal, hence opamp nonlinearity will cause very little harmonic distortion. Nonlinearity...

  4. Prevalence of Neonatal Jaundice on Central Hospital, Warri, Delta ...

    African Journals Online (AJOL)

    Methods: 272 babies (aged 1 – 30 days) the Neonatal Clinic of the Department of Child Health, Central Hospital, Warri, Delta State between June 2009 and June 2010 were examined daily for evidence of jaundice. Those with serum bilirubin ³15mg/100ml were subjected to additional clinical and laboratory investigations to ...

  5. Mantle electrical conductivity profile of Niger delta region

    Indian Academy of Sciences (India)

    The mantle electrical conductivity-depth profile of the Niger delta region in Nigeria has been determined using solar quiet day ionospheric current (Sq).The magnetometer data obtained in 2010 from geomagnetic stations installed in Lagos by magnetic dataset (MAGDAS) in 2008 and data from magnetometers installed in ...

  6. The Niger Delta: State Repression and Violence Nexus

    African Journals Online (AJOL)

    crosdel emuedo

    2005-02-19

    Feb 19, 2005 ... This explains its concern only with unimpeded access to crude oil at very cheap ... The people of the Niger Delta on the other hand, places premium on the concept of human ... going amnesty, over 123 hostages were taken.

  7. On approximation and energy estimates for delta 6-convex functions.

    Science.gov (United States)

    Saleem, Muhammad Shoaib; Pečarić, Josip; Rehman, Nasir; Khan, Muhammad Wahab; Zahoor, Muhammad Sajid

    2018-01-01

    The smooth approximation and weighted energy estimates for delta 6-convex functions are derived in this research. Moreover, we conclude that if 6-convex functions are closed in uniform norm, then their third derivatives are closed in weighted [Formula: see text]-norm.

  8. On approximation and energy estimates for delta 6-convex functions

    Directory of Open Access Journals (Sweden)

    Muhammad Shoaib Saleem

    2018-02-01

    Full Text Available Abstract The smooth approximation and weighted energy estimates for delta 6-convex functions are derived in this research. Moreover, we conclude that if 6-convex functions are closed in uniform norm, then their third derivatives are closed in weighted L2 $L^{2}$-norm.

  9. Questioning triple rice intensification on the Vietnamese mekong delta floodplains

    NARCIS (Netherlands)

    Tran, Dung Duc; Halsema, van Gerardo; Hellegers, Petra J.G.J.; Ludwig, Fulco; Wyatt, Andrew

    2018-01-01

    Large areas of the Vietnamese Mekong Delta floodplains (VMDF) are protected by high dikes to facilitate three rice crops per year. While this has increased rice production, there is evidence that triple rice systems have negative long-term effects, both environmental and economic. Double rice

  10. The search for environmental justice in the Niger Delta and ...

    African Journals Online (AJOL)

    Right from the beginning Man has been given the privilege by his Creator to tender the earth and take dominion over his environment. But for the impoverished people of the Niger Delta region, the mainstay of Nigeria's oil wealth, the situation is ironically abysmal. The region has been the scene of protest, sometimes ...

  11. What are pregnant women in a rural Niger Delta community's ...

    African Journals Online (AJOL)

    To date, studies have sought cause and effect and have neglected the opinion of the people about what they perceive to be problematic and what they believe constitutes satisfactory maternity service provision. An exploratory qualitative study was carried out to identify pregnant women in a rural Niger Delta community's ...

  12. Production and decay properties of the delta (970) meson

    International Nuclear Information System (INIS)

    Gay, J.B.; Chaloupka, V.; Gavillet, Ph.; Hemingway, R.J.; Marzano, F.; Montanet, L.; Blokzijl, R.; Jongejans, B.; Massaro, G.G.G.; Heinen, P.M.; Metzger, W.J.; Timmermans, J.J.M.

    1976-01-01

    Using an 80 events per microbarn sample of K - p interactions at 4.2 GeV/c the production and decay properties of the delta(970) have been investigated in the following reactions: K - p→Σ + (1385)etaπ - and K - p→Σ + (1385)K 0 K - . (Auth.)

  13. Obesity and Health Risk of Children in the Mississippi Delta

    Science.gov (United States)

    Gamble, Abigail; Waddell, Dwight; Ford, M. Allison; Bentley, John P.; Woodyard, Catherine D.; Hallam, Jeffrey S.

    2012-01-01

    Background: Mississippi (MS) Delta adults and youth report obesity rates far exceeding those of the state and nation. State law requires in-school physical activity and nutrition practices to address childhood obesity but does not require evaluation of outcomes, specifically the impact on weight-related outcomes. This paper offers 3 things: (1)…

  14. Leena delta rännujutud / Riho Västrik

    Index Scriptorium Estoniae

    Västrik, Riho, 1965-

    2010-01-01

    Reisikiri Leena jõest filmi tegeva filmimeeskonna matkast Leena jõe delta tundras, kus satuti ka 1879. aastal purjelaeval "Jeannette" põhjapoolust vallutama tulnud ameerika polaaruurija DeLongi matmispaiga ja mälestusmärgi juurde

  15. Enhancing stakeholder participation in the Niger Delta region: the ...

    African Journals Online (AJOL)

    Nigeria's indigenous people, found in the Niger Delta area, have for many years experienced developmental challenges associated with oil exploration. The region has been perennially engulfed in various forms of agitation pertaining to self-government and resource control. Over the years, attempts to solve these ...

  16. Changes in the areal extents of the Athabasca River, Birch River, and Cree Creek Deltas, 1950-2014, Peace-Athabasca Delta, Canada

    Science.gov (United States)

    Timoney, Kevin; Lee, Peter

    2016-04-01

    Deltas form where riverborne sediment accumulates at the interface of river mouths and their receiving water bodies. Their areal extent is determined by the net effect of processes that increase their extent, such as sediment accumulation, and processes that decrease their extent, such as erosion and subsidence. Through sequential mapping and construction of river discharge and sediment histories, this study examined changes in the subaerial extents of the Cree Creek and Athabasca River Deltas (both on the Athabasca River system) and the Birch River Delta in northern Canada over the period 1950-2014. The purpose of the study was to determine how, when, and why the deltas changed in areal extent. Temporal growth patterns were similar across the Athabasca and Birch River systems indicative of a climatic signal. Little or no areal growth occurred from 1950 to 1968; moderate growth occurred between 1968 and the early to mid-1980s; and rapid growth occurred between 1992 and 2012. Factors that affected delta progradation included dredging, sediment supply, isostatic drowning, delta front bathymetry, sediment capture efficiency, and storms. In relation to sediment delivered, areal growth rates were lowest in the Athabasca Delta, intermediate in the Birch Delta, and highest in the Cree Creek Delta. Annual sediment delivery is increasing in the Cree Creek Delta; there were no significant trends in annual sediment delivery in the Birch and Athabasca Deltas. There was a lag of up to several years between sediment delivery events and progradation. Periods of delta progradation were associated with low water levels of the receiving basins. Predicted climate-change driven declines in river discharge and lake levels may accelerate delta progradation in the region. In the changing ecosystems of northeastern Alberta, inadequate monitoring of vegetation, landforms, and sediment regimes hampers the elucidation of the nature, rate, and causality of ecosystem changes.

  17. delta 6 Hexadecenoic acid is synthesized by the activity of a soluble delta 6 palmitoyl-acyl carrier protein desaturase in Thunbergia alata endosperm.

    Science.gov (United States)

    Cahoon, E B; Cranmer, A M; Shanklin, J; Ohlrogge, J B

    1994-11-04

    delta 6 Hexadecenoic acid (16:1 delta 6) composes more than 80% of the seed oil of Thunbergia alata. Studies were conducted to determine the biosynthetic origin of the double bond of this unusual fatty acid. Assays of fractions of developing T. alata seed endosperm with [1-14C]palmitoyl (16:0)-acyl carrier protein (ACP) revealed the presence of a soluble delta 6 desaturase activity. This activity was greatest when 16:0-ACP was provided as a substrate, whereas no desaturation of the coenzyme A ester of this fatty acid was detected. In addition, delta 6 16:0-ACP desaturase activity in T. alata endosperm extracts was dependent on the presence of ferredoxin and molecular oxygen and was stimulated by catalase. To further characterize this enzyme, a cDNA encoding a diverged acyl-ACP desaturase was isolated from a T. alata endosperm cDNA library using polymerase chain reaction with degenerate oligonucleotides corresponding to conserved amino acid sequences in delta 9 stearoyl (18:0)- and delta 4 16:0-ACP desaturases. The primary structure of the mature peptide encoded by this cDNA shares 66% identity with the mature castor delta 9 18:0-ACP desaturase and 57% identity with the mature coriander delta 4 16:0-ACP desaturase. Extracts of Escherichia coli that express the T. alata cDNA catalyzed the delta 6 desaturation of 16:0-ACP. These results demonstrate that 16:1 delta 6 in T. alata endosperm is formed by the activity of a soluble delta 6 16:0-ACP desaturase that is structurally related to the delta 9 18:0- and delta 4 16:0-ACP desaturases. Implications of this work to an understanding of active site structures of acyl-ACP desaturases are discussed.

  18. Characterizing the surface circulation in the Ebro Delta using a HF radar data-model approach

    Science.gov (United States)

    Lorente Jimenez, Pablo; Piedracoba Varela, Silvia; Soto-Navarro, Javier; Garcia-Sotillo, Marcos; Alvarez Fanjul, Enrique

    2016-04-01

    One year-long (2014) quality-controlled current observations from a CODAR SeaSonde High Frequency (HF) radar network deployed in the Ebro Delta (northwestern Mediterranean) were combined with operational products provided by a regional ocean forecasting system named IBI (Iberia-Biscay-Ireland) in order to comprehensively portray the ocean state and its variability. First, accurate HF radar data were used as benchmark for the rigorous validation of IBI performance by means of the computation of skill metrics and quality indicators. The analysis of the monthly averaged current maps for 2014 showed that IBI properly captured the prevailing dynamic features of the coastal circulation observed by the HF radar, according to the resemblance of circulation patterns and the eddy kinetic energy spatial distribution. The model skill assessment was completed with an exploration of dominant modes of variability both in time and space. The EOF analysis confirmed that the modeled surface current field evolved in space and time according to three significantly dominant modes of variability which accounted for the 49.2% of the total variance, in close agreement with the results obtained for the HF radar (46.1%). The response of the subtidal surface current field to prevalent wind regimes in the study area was examined in terms of induced circulation structures by performing a conditional averaging approach. This data-model synergistic approach has proved to be valid to operationally monitor and describe the complex coastal circulation in Ebro Delta despite the observed model drawbacks in terms of reduced energy content in surface currents and some inaccuracies in the wind-driven low frequency response. This integrated methodology constitutes a powerful tool for improving operational ocean forecasting systems at European level within the frame of the Copernicus Marine Environment Monitoring Service (CMEMS). It also facilitates high-stakes decision-making for coastal management and

  19. Implications of agricultural land use change to ecosystem services in the Ganges delta.

    Science.gov (United States)

    Islam, G M Tarekul; Islam, A K M Saiful; Shopan, Ahsan Azhar; Rahman, Md Munsur; Lázár, Attila N; Mukhopadhyay, Anirban

    2015-09-15

    Ecosystems provide the basis for human civilization and natural capital for green economy and sustainable development. Ecosystem services may range from crops, fish, freshwater to those that are harder to see such as erosion regulation, carbon sequestration, and pest control. Land use changes have been identified as the main sources of coastal and marine pollution in Bangladesh. This paper explores the temporal variation of agricultural land use change and its implications with ecosystem services in the Ganges delta. With time agricultural lands have been decreased and wetlands have been increased at a very high rate mainly due to the growing popularity of saltwater shrimp farming. In a span of 28 years, the agricultural lands have been reduced by approximately 50%, while the wetlands have been increased by over 500%. A large portion (nearly 40%) of the study area is covered by the Sundarbans which remained almost constant which can be attributed to the strict regulatory intervention to preserve the Sundarbans. The settlement & others land use type has also been increased to nearly 5%. There is a gradual uptrend of shrimp and fish production in the study area. The findings suggest that there are significant linkages between agricultural land use change and ecosystem services in the Ganges delta in Bangladesh. The continuous decline of agricultural land (due to salinization) and an increase of wetland have been attributed to the conversion of agricultural land into shrimp farming in the study area. Such land use change requires significant capital, therefore, only investors and wealthier land owners can get the higher profit from the land conversion while the poor people is left with the environmental consequences that affect their long-term lives and livelihood. An environmental management plan is proposed for sustainable land use in the Ganges delta in Bangladesh. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Extracorporeal gas exchange with the DeltaStream rotary blood pump in experimental lung injury.

    Science.gov (United States)

    Dembinski, Rolf; Kopp, Rüdger; Henzler, Dietrich; Hochhausen, Nadine; Oslender, Nicole; Max, Martin; Rossaint, Rolf; Kuhlen, Ralf

    2003-06-01

    In most severe cases of the acute respiratory distress syndrome, veno-venous extracorporeal membrane oxygenation (ECMO) can be used to facilitate gas exchange. However, the clinical use is limited due to the size and the concomitant risk of severe adverse events of conventionally-used centrifugal blood pumps with high extracorporeal blood volumes. The DeltaStream blood pump is a small-sized rotary blood pump that may reduce extracorporeal blood volume, foreign surfaces, contact activation of the coagulation system, and blood trauma. The aim of the present study was to test the safety and efficacy of the DeltaStream pump for ECMO in animals with normal lung function and experimental acute lung injury (ALI). Therefore, veno-venous ECMO was performed for 6 hours in mechanically ventilated pigs with normal lung function (n=6) and with ALI induced by repeated lung lavage (n=6) with a blood flow of 30% of the cardiac output. Gas flow with a FiO2 of 1.0 was set to equal blood flow. With a mean activated clotting time of 121 +/- 22 s, no circulatory impairment or thrombus formation was revealed during ECMO. Furthermore, free plasma Hb did not increase. In controls, hemodynamics and gas exchange remained unchanged. In animals with ALI, hemodynamics remained stable and gas transfer across the extracorporeal oxygenators was optimal, but only in 2 animals was a marked increase in PaO2 observed. CO2 removal was efficacious in all animals. We concluded that the DeltaStream blood pump may be used for veno-venous ECMO without major blood damage or hemodynamic impairment.

  1. RATING OF SOCIAL MEDIA MARKETING COMPETENCIES POSSESSED BY ENTREPRENEURS IN DELTA STATE, NIGERIA

    OpenAIRE

    Ezenwafor, J. I.; Onokpaunu, Michel O.; Nna-Emmanuel, Sarah W.

    2017-01-01

    The need for wide utilization of social media marketing for entrepreneurial development in Delta State necessitated this study which sought to determine how competent practicing entrepreneurs are for their use in Delta State. One research question guided the study. A survey research design was adopted. The population consisted of 200 entrepreneurs in Delta North Senatorial District of Delta State. A validated 22 item on a 5-point rating scale questionnaire was used for data collection. Mean a...

  2. The changing hydro-ecological dynamics of rivers and deltas of the Western Indian Ocean: Anthropogenic and environmental drivers, local adaptation and policy response

    Science.gov (United States)

    Duvail, Stéphanie; Hamerlynck, Olivier; Paron, Paolo; Hervé, Dominique; Nyingi, Wanja D.; Leone, Michele

    2017-10-01

    The rivers flowing into the Western Indian Ocean have steep headwater gradients and carry high sediment loads. In combination with strong tides and seasonal rainfall, these rivers create dynamic deltas with biodiversity-rich and productive ecosystems that, through flooding, have sustained indigenous use systems for centuries. However, river catchments are rapidly changing due to deforestation. Hydropower dams also increasingly alter flood characteristics, reduce sediment supply and contribute to coastal erosion. These impacts are compounded by climate change. Altogether, these changes affect the livelihoods of the delta users. Here, based on prior works that we and others have conducted in the region, we analyse the drivers of these hydro-ecological changes. We then provide recommendations for improved dam design and operations to sustain the underlying delta-building processes, the ecosystem values and the needs of the users.

  3. Differential entrainment of neuroelectric delta oscillations in developmental dyslexia.

    Directory of Open Access Journals (Sweden)

    Fruzsina Soltész

    Full Text Available Oscillatory entrainment to the speech signal is important for language processing, but has not yet been studied in developmental disorders of language. Developmental dyslexia, a difficulty in acquiring efficient reading skills linked to difficulties with phonology (the sound structure of language, has been associated with behavioural entrainment deficits. It has been proposed that the phonological 'deficit' that characterises dyslexia across languages is related to impaired auditory entrainment to speech at lower frequencies via neuroelectric oscillations (<10 Hz, 'temporal sampling theory'. Impaired entrainment to temporal modulations at lower frequencies would affect the recovery of the prosodic and syllabic structure of speech. Here we investigated event-related oscillatory EEG activity and contingent negative variation (CNV to auditory rhythmic tone streams delivered at frequencies within the delta band (2 Hz, 1.5 Hz, relevant to sampling stressed syllables in speech. Given prior behavioural entrainment findings at these rates, we predicted functionally atypical entrainment of delta oscillations in dyslexia. Participants performed a rhythmic expectancy task, detecting occasional white noise targets interspersed with tones occurring regularly at rates of 2 Hz or 1.5 Hz. Both groups showed significant entrainment of delta oscillations to the rhythmic stimulus stream, however the strength of inter-trial delta phase coherence (ITC, 'phase locking' and the CNV were both significantly weaker in dyslexics, suggestive of weaker entrainment and less preparatory brain activity. Both ITC strength and CNV amplitude were significantly related to individual differences in language processing and reading. Additionally, the instantaneous phase of prestimulus delta oscillation predicted behavioural responding (response time for control participants only.

  4. Effects of external stores on the air combat capability of a delta wing fighter

    Science.gov (United States)

    Spearman, M. L.; Sawyer, W. C.

    1977-01-01

    Delta wing point-design fighters with two pylon mounted missiles and aft tail controls (similar to several Soviet designs) have been investigated for a Mach number range from about 0.6 to 2.0. Whereas minimum drag penalties that are expected with the addition of external stores do occur, the effects at higher lifts, corresponding to maneuvering flight, are less severe and often favorable. The drag-due-to-lift factor is less with stores on although the lift curve slope is unaffected. The longitudinal stability level is reduced by the addition of stores while the pitch control effectiveness is unchanged. The directional stability was generally reduced at subsonic speeds and increased at supersonic speeds by the addition of stores but sufficiently high stability levels are obtainable that are compatible with the longitudinal maneuvering limits. Some examples of the potential maneuvering capability in terms of normal acceleration and turn radius are included.

  5. Impact of alpha-, gamma-, and delta-tocopherol on the radiation induced oxidation of rapeseed oil triacylglycerols

    Energy Technology Data Exchange (ETDEWEB)

    Braunrath, Robert; Isnardy, Bettina; Solar, Sonja, E-mail: sonja.solar@univie.ac.at; Elmadfa, Ibrahim

    2010-07-15

    Gamma-irradiation (doses: 2, 4, 7, and 10 kGy) was used as oxidation tool to study the antioxidant effects of alpha-, gamma-, and delta-tocopherol (enrichments 500-5000 ppm) in purified rapeseed oil triacylglycerols (RSOTG). Fatty acid composition, tocopherol degradation, primary (conjugated dienes (CD) and peroxide value (POV)) and secondary (p-anisidine value) oxidation products were chosen as test parameters. Fatty acid composition did not change. While secondary oxidation products could not be found in the irradiated samples, the POVs and CDs showed a significant, dose-dependent increase. alpha-Tocopherol did not inhibit the formation of peroxides, whereas gamma- and delta-tocopherol reduced the POVs by more than 30%. No uniform effect of the different tocopherol concentrations at the particular doses could be established. The influence of the individual tocopherols on the CD formation was not pronounced. The degradation of the tocopherols decreased with increasing concentration. None of the tocopherols showed a prooxidant effect.

  6. Oil and Security in Nigeria: The Niger Delta Crisis | Owolabi | Africa ...

    African Journals Online (AJOL)

    This paper examines oil and security in Nigeria, with special reference to the crisis-ravaged Niger Delta. Its focus on the Niger Delta and its festering crisis stems from that region's critical importance to Nigeria. As the nation's treasure base, the Niger Delta provides over 80 percent of government revenues, 95 percent of ...

  7. The coastal system of the Volta delta, Ghana : Strategies and opportunities for development

    NARCIS (Netherlands)

    Roest, Lambertus W.M.

    2018-01-01

    The Volta delta is a very dynamic environment, forming the interface between the Volta river and the Atlantic ocean. The delta is a home for many communities, settled both at the shorelines and more inland. Furthermore the delta provides great natural values and a habitat for many species.
    The

  8. Contrasting morphodynamics in alluvial fans and fan deltas: effect of the downstream boundary

    NARCIS (Netherlands)

    Dijk, M. van; Kleinhans, M.G.; Postma, G.; Kraal, E.

    2012-01-01

    Alluvial fans and fan deltas can, in principle, have exactly the same upstream conditions, but fan deltas by definition have ponding water at their downstream boundary. This ponding creates effects on the autogenic behaviour of fan deltas, such as backwater adaptation, mouth bars and backward

  9. Challenges and Approaches in River Delta Planning - report on training workshop

    NARCIS (Netherlands)

    Wosten, J.H.M.; Douven, W.; Long Phi, H.; Fida Abdullah Khan, M.

    2012-01-01

    River delta’s, like the Mekong Delta (Vietnam), Ganges-Brahmaputra Delta (Bangladesh), Irrawady (Myanmar) and Ciliwung Delta (Indonesia) are developing rapidly and characterized by large-scale urbanization and industrialization processes. They are facing serious planning challenges related to issues

  10. T-cell receptor gamma delta bearing cells in normal human skin

    NARCIS (Netherlands)

    Bos, J. D.; Teunissen, M. B.; Cairo, I.; Krieg, S. R.; Kapsenberg, M. L.; Das, P. K.; Borst, J.

    1990-01-01

    T-cell antigen receptors (TCR) are divided into common alpha beta and less common gamma delta types. In the murine skin, TCR gamma delta+ cells have been reported to form the great majority of epidermal T lymphocytes. We have examined the relative contribution of TCR alpha beta+ and TCR gamma delta+

  11. A new identification method for energetic ion {delta}E-E telescopes

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Cesar [Departamento de Fisica, Universidad de Alcala, 28871 Alcala de Henares, Madrid (Spain); Institut fuer Experimentelle und Angewandte Physik, Christian-Albrechts, Universitaet zu Kiel, 24118 Kiel (Germany); Bronchalo, Enrique [Departamento de Fisica, Universidad de Alcala, 28871 Alcala de Henares, Madrid (Spain); Departamento de Fisica y Arquitectura de Computadores, Universidad Miguel Hernandez, Avda. Universidad s/n, 03202 Elche, Alicante (Spain)], E-mail: ebronchalo@umh.es; Medina, Jose [Departamento de Fisica, Universidad de Alcala, 28871 Alcala de Henares, Madrid (Spain)

    2007-11-21

    A new ion identification method for {delta}E-E telescopes is presented. The method works by counting data points under {delta}E(E) curves on {delta}E-E diagrams. These curves are obtained by simulating the telescope response to a flux of energetic ions. The method is checked against three published methods applied to several experimental data sets.

  12. Remote Sensing Monitoring Methods for Detecting Invasive Weed Coverage in Delta Waterways and Bay Marshlands

    Science.gov (United States)

    Potter, Christopher

    2018-01-01

    This presentation is part of the Independent Science Board of the State of California Delta Stewardship Council brown bag seminar series on the "How the Delta is Monitored", followed with a panel discussion. Various remote sensing approaches for aquatic vegetation will be reviewed. Key research and application issues with remote sensing monitoring in the Delta will be addressed.

  13. Effect of delta wing on the particle flow in a novel gas supersonic separator

    DEFF Research Database (Denmark)

    Wen, Chuang; Yang, Yan; Walther, Jens Honore

    2016-01-01

    The present work presents numerical simulations of the complex particle motion in a supersonic separator with a delta wing located in the supersonic flow. The effect of the delta wing on the strong swirling flow is analysed using the Discrete Particle Method. The results show that the delta wings...

  14. Grain-size sorting in grainflows at the lee side of deltas

    NARCIS (Netherlands)

    Kleinhans, M.G.

    2005-01-01

    The sorting of sediment mixtures at the lee slope of deltas (at the angle of repose) is studied with experiments in a narrow, deep flume with subaqueous Gilbert-type deltas using varied flow conditions and different sediment mixtures. Sediment deposition and sorting on the lee slope of the delta

  15. Plant delta 15N correlates with the transpiration efficiency of nitrogen acquisition in tropical trees.

    Science.gov (United States)

    Cernusak, Lucas A; Winter, Klaus; Turner, Benjamin L

    2009-11-01

    Based upon considerations of a theoretical model of (15)N/(14)N fractionation during steady-state nitrate uptake from soil, we hypothesized that, for plants grown in a common soil environment, whole-plant delta(15)N (deltaP) should vary as a function of the transpiration efficiency of nitrogen acquisition (F(N)/v) and the difference between deltaP and root delta(15)N (deltaP - deltaR). We tested these hypotheses with measurements of several tropical tree and liana species. Consistent with theoretical expectations, both F(N)/v and deltaP - deltaR were significant sources of variation in deltaP, and the relationship between deltaP and F(N)/v differed between non-N(2)-fixing and N(2)-fixing species. We interpret the correlation between deltaP and F(N)/v as resulting from variation in mineral nitrogen efflux-to-influx ratios across plasma membranes of root cells. These results provide a simple explanation of variation in delta(15)N of terrestrial plants and have implications for understanding nitrogen cycling in ecosystems.

  16. Implications for future survival of delta smelt from four climate change scenarios for the Sacramento–San Joaquin Delta, California

    Science.gov (United States)

    Brown, Larry R.; Bennett, William A.; Wagner, R. Wayne; Morgan-King, Tara; Knowles, Noah; Feyrer, Frederick; Schoellhamer, David H.; Stacey, Mark T.; Dettinger, Mike

    2013-01-01

    Changes in the position of the low salinity zone, a habitat suitability index, turbidity, and water temperature modeled from four 100-year scenarios of climate change were evaluated for possible effects on delta smelt Hypomesus transpacificus, which is endemic to the Sacramento–San Joaquin Delta. The persistence of delta smelt in much of its current habitat into the next century appears uncertain. By mid-century, the position of the low salinity zone in the fall and the habitat suitability index converged on values only observed during the worst droughts of the baseline period (1969–2000). Projected higher water temperatures would render waters historically inhabited by delta smelt near the confluence of the Sacramento and San Joaquin rivers largely uninhabitable. However, the scenarios of climate change are based on assumptions that require caution in the interpretation of the results. Projections like these provide managers with a useful tool for anticipating long-term challenges to managing fish populations and possibly adapting water management to ameliorate those challenges.

  17. 78 FR 22911 - Delta Air Lines, Inc., Reservation Sales and Customer Care Call Center, Seatac, WA; Delta Air...

    Science.gov (United States)

    2013-04-17

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-82,197; TA-W-82,197A] Delta Air... requested administrative reconsideration of the negative determination regarding workers' eligibility to... threatened with total or partial separation from employment on the date of certification through two years...

  18. Unexpected {delta}{sup 18}O and {delta}{sup 2}H Variability of Groundwater in the Eastern Paris Basin

    Energy Technology Data Exchange (ETDEWEB)

    Gourcy, L.; Petelet-Giraud, E. [BRGM Service EAU, Orleans (France)

    2013-07-15

    The Paris Basin covers about one-third of the total surface area of France. In 2009, two campaigns sampling 25 boreholes tapping Tertiary aquifers were carried out in the Basin. These aquifers are recharged at a similar altitude and the groundwater age is too young to have registered climate change. In the past, regional studies included the use of isotopes to understand groundwater origin and dynamics. Both {delta}{sup 18}O and {delta}{sup 2}H as well as ages (CFC/SF{sub 6)} and chemical components were determined in all collected samples. A noticeable stable isotope 'anomaly' appears in the south-western part of the Basin, where the average {delta}{sup 18}O and {delta}{sup 2}H values are more depleted and do not fit the pattern given by the continental effect in this area. A regional particularity of the spatial distribution of such isotopes in precipitation may be possible, but should be confirmed by additional work. (author)

  19. Trophic gradients in a large-river delta: Ecological structure determined by connectivity gradients in the Danube Delta (Romania)

    NARCIS (Netherlands)

    Coops, H.; Buijse-Bogdan, L.L.; Buijse, A.D.; Constantinescu, A.; Covaliov, S.; Hanganu, J.; Ibelings, B.W.; Menting, G.; Navodaru, I.; Oosterberg, W.; Staras, M.; Torok, L.

    2008-01-01

    There are over 300 lakes interconnected by riverbranches and man-made canals in the Danube Delta (Romania). A multidisciplinary survey of these riverine lakes situated in large Wetland complexes was made comprising hydrological modelling, remote sensing and monitoring of water quality, plankton,

  20. Biomass and Carbon Sequestration in Community Mangrove Plantations and a Natural Regeneration Stand in the Ayeyarwady Delta, Myanmar

    Science.gov (United States)

    Thant, Y. M.; Kanzaki, M.; nil

    2011-12-01

    Mangroves in the Ayeyarwady Delta is one of the most threatened ecosystems, and is rapidly disappearing as in many tropical countries. The deforestation and degradation of mangrove forest in the Ayeryarwady Delta results in the shortage of wood resources and declining of environmental services that have been provided by the mangrove ecosystem. Cyclone Nargis struck the Ayeyarwady Delta on 2 May 2008 with an intensity unprecedented in the history of Myanmar. The overexploitation of mangroves because of local demands for fuel wood and charcoal and the conversion of mangrove forest land into agricultural land or shrimp farms over the past decades have increased the loss of human life and the damage to settlements caused by the Cyclone.The biomass study was conducted in September of 2006 in Bogale Township in the Ayeyarwady Delta and continued monitoring in September of each year from 2007 to 2010. Above and below ground biomass was studied in six years old mangrove plantations of Avicenia marina (Am), Avicenia officinalis (Ao) and Sonneratia apetala (Sa) and a naturally regenerated stand under regeneration improving felling operation (NR: consists of Ceriops decandra, Bruguiera sexangula, and Aegicerus corniculatum) protected for seven years since 2000. These stands were established by small-scale Community Forestry scheme on abandoned paddy fields where natural mangroves once existed. Common allometric equations were developed for biomass estimation by performing regressions between dry weights of trees as dependent variables and biometric parameters such as stem diameter, height and wood density as independent variables. The above and below ground biomass in NR stand (70 Mg ha-1 and 104 Mg ha-1) was the greatest (P mangrove plantation and induced natural regeneration as a carbon sequestration tool. The establishment of mangrove plantations appeared to be one measure for reducing the risk of cyclone damage after the Cyclone Nargis. This may reduce future human loss

  1. Transient reduction of tinnitus intensity is marked by concomitant reductions of delta band power

    Directory of Open Access Journals (Sweden)

    Weisz Nathan

    2008-01-01

    Full Text Available Abstract Background Tinnitus is an auditory phantom phenomenon characterized by the sensation of sounds without objectively identifiable sound sources. To date, its causes are not well understood. Previous research found altered patterns of spontaneous brain activity in chronic tinnitus sufferers compared to healthy controls, yet it is unknown whether these abnormal oscillatory patterns are causally related to the tinnitus sensation. Partial support for this notion comes from a neurofeedback approach developed by our group, in which significant reductions in tinnitus loudness could be achieved in patients who successfully normalized their patterns of spontaneous brain activity. The current work attempts to complement these studies by scrutinizing how modulations of tinnitus intensity alter ongoing oscillatory activity. Results In the present study the relation between tinnitus sensation and spontaneous brain activity was investigated using residual inhibition (RI to reduce tinnitus intensity and source-space projected magnetencephalographic (MEG data to index brain activity. RI is the sustained reduction (criteria: 50% for at least 30 s in tinnitus loudness after cessation of a tonal tinnitus masker. A pilot study (n = 38 identified 10 patients who showed RI. A significant reduction of power in the delta (1.3–4.0 Hz frequency band was observed in temporal regions during RI (p ≤ 0.001. Conclusion The current results suggest that changes of tinnitus intensity induced by RI are mediated by alterations in the pathological patterns of spontaneous brain activity, specifically a reduction of delta activity. Delta activity is a characteristic oscillatory activity generated by deafferented/deprived neuronal networks. This implies that RI effects might reflect the transient reestablishment of balance between excitatory and inhibitory neuronal assemblies, via reafferentation, that have been perturbed (in most tinnitus individuals by hearing damage. As

  2. IMPROVING THE AERODYNAMICS OF A TRANSPORT AIRCRAFT WING USING A DELTA PLANFORM WINGTIP LEADING EDGE EXTENSION

    Directory of Open Access Journals (Sweden)

    D. Gueraiche

    2018-01-01

    Full Text Available The article explores the possibility of improving the aerodynamic properties of a supercritical-airfoil wing, typical for a modern passenger aircraft, using delta planform passive devices of large relative areas, installed along the leading edge at the wing tip. Delta extensions of various configurations were considered to be used as wingtip devices, potentially improving or completely replacing classical R. Whitcomb winglets. As a result of two- and three-dimensional CFD simulations performed on DLR-F4 wing-body prototype, the potential advantage of these devices was confirmed, particularly when they are installed in a combination with an elliptical planform, largely swept, raked winglet in terms of reducing the induced drag and increasing the aerodynamic lift-to-drag ratio at flight angles of attack. The growth in lift-to-drag ratio applying these devices owes it solely to the drop in drag, without increasing the lift force acting on the wing. In comparison to the classical winglets that lead to a general increase in lifting and lateral forces acting on the wing structure, resulting in a weight penalty, the Wingtip Ledge Edge Triangular Extension (WLETE yields the same L/D ratio increase, but with a much smaller increase in the wing loading. A study has been made of the characteristics of the local (modified airfoil in the WLETE zone in a two-dimensional flow context, and a quantitative analysis has been conducted of the influence of WLETE on both the profile and induced drag components, as well as its influence on the overall lift coefficient of the wing. The resulted synthesis of the WLETE influence on the wing L/D ratio will consist of its influence on each of these components. A comparison of the efficiency of using delta extensions against classical winglets was carried out in a multidisciplinary way, where in addition to the changes in aerodynamic coefficients of lift and drag, the increments of magnitude and distribution of the loads

  3. Alopecia in a viable phospholipase C delta 1 and phospholipase C delta 3 double mutant.

    Directory of Open Access Journals (Sweden)

    Fabian Runkel

    Full Text Available BACKGROUND: Inositol 1,4,5trisphosphate (IP(3 and diacylglycerol (DAG are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD forms one class. Studies with functional inactivation of Plcd isozyme encoding genes in mice have revealed that loss of both Plcd1 and Plcd3 causes early embryonic death. Inactivation of Plcd1 alone causes loss of hair (alopecia, whereas inactivation of Plcd3 alone has no apparent phenotypic effect. To investigate a possible synergy of Plcd1 and Plcd3 in postnatal mice, novel mutations of these genes compatible with life after birth need to be found. METHODOLOGY/PRINCIPAL FINDINGS: We characterise a novel mouse mutant with a spontaneously arisen mutation in Plcd3 (Plcd3(mNab that resulted from the insertion of an intracisternal A particle (IAP into intron 2 of the Plcd3 gene. This mutation leads to the predominant expression of a truncated PLCD3 protein lacking the N-terminal PH domain. C3H mice that carry one or two mutant Plcd3(mNab alleles are phenotypically normal. However, the presence of one Plcd3(mNab allele exacerbates the alopecia caused by the loss of functional Plcd1 in Del(9olt1Pas mutant mice with respect to the number of hair follicles affected and the body region involved. Mice double homozygous for both the Del(9olt1Pas and the Plcd3(mNab mutations survive for several weeks and exhibit total alopecia associated with fragile hair shafts showing altered expression of some structural genes and shortened phases of proliferation in hair follicle matrix cells. CONCLUSIONS/SIGNIFICANCE: The Plcd3(mNab mutation is a novel hypomorphic mutation of Plcd3. Our investigations suggest that Plcd1 and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface.

  4. Erosion of the Mekong delta: the role of human activities

    Science.gov (United States)

    Anthony, E.; Dussouillez, P.; Goichot, M.; Brunier, G.; Dolique, F.; Nguyen, V.; Loisel, H.; Mangin, A.; Vantrepotte, V.

    2013-12-01

    River deltas are threatened by dams, dykes, flow channelling, and aggregate extraction. These activities outweigh climate change and sea-level rise in causing delta vulnerability1, and will aggravate the impacts to be expected from these effects2. We show here from analysis of: (1) delta channel morphology and sediment budgets, and (2) satellite imagery, that the Mekong delta, considered as the world's third largest, and hitherto strongly prograding, is now in a phase of large-scale erosion. We discuss the mechanistic links involved in erosion and the way these are related to human activities. High-resolution (2.5 m) SPOT 5 images for the years 2003, 2007, 2011/12 covering 405 km of the delta shoreline show an overall retreat rate of over 8 m a year. 75% of the analysed shoreline, i.e., the muddy western sector, is now retreating at rates exceeding 50 m a year in places. The sandy river-mouth sector maintains a semblance of stability, but with strong variations. We attribute erosion to a cascade of morphosedimentary changes linked to sediment mining from the deltaic channels and upstream dam interception. We estimated from Meris satellite imagery an annual 5% decrease in surface suspended concentrations exiting at the mouths of the Mekong over the period 2003-2011 that may reflect increased trapping of mud behind dams in China. We also infer modification of river-mouth and coastal mud storage patterns resulting from a loss of ca. 200 million m3 of delta channel sediments between 1998 and 2008 from aggregate extraction. Dykes have been shown to result in increased channel flow velocities during the high-discharge monsoon season, favouring further channel deepening3. Stronger river-mouth outflow velocities during this season may be leading to export of a greater proportion of mud far offshore of the coastal longshore transport corridor that ensured mud supply to, and past progradation of, the muddy western coast. In contrast, greater seawater penetration in the

  5. Within-canopy and ozone fumigation effects on delta13C and Delta18O in adult beech (Fagus sylvatica) trees: relation to meteorological and gas exchange parameters.

    Science.gov (United States)

    Gessler, Arthur; Löw, Markus; Heerdt, Christian; de Beeck, Maarten Op; Schumacher, Johannes; Grams, Thorsten E E; Bahnweg, Günther; Ceulemans, Reinhart; Werner, Herbert; Matyssek, Rainer; Rennenberg, Heinz; Haberer, Kristine

    2009-11-01

    In this study, the effects of different light intensities either in direct sunlight or in the shade crown of adult beech (Fagus sylvatica L.) trees on delta13C and Delta18O were determined under ambient (1 x O3) and twice-ambient (2 x O3) atmospheric ozone concentrations during two consecutive years (2003 and 2004). We analysed the isotopic composition in leaf bulk, leaf cellulose, phloem and xylem material and related the results to (a) meteorological data (air temperature, T and relative humidity, RH), (b) leaf gas exchange measurements (stomatal conductance, g(s); transpiration rate, E; and maximum photosynthetic activity, A(max)) and (c) the outcome of a steady-state evaporative enrichment model. Delta13C was significantly lower in the shade than in the sun crown in all plant materials, whilst Delta18O was increased significantly in the shade than in the sun crown in bulk material and cellulose. Elevated ozone had no effect on delta13C, although Delta18O was influenced by ozone to varied degrees during single months. We observed significant seasonal changes for both parameters, especially in 2004, and also significant differences between the study years. Relating the findings to meteorological data and gas exchange parameters, we conclude that the differences in Delta18O between the sun and the shade crown were predominantly caused by the Péclet effect. This assumption was supported by the modelled Delta18O values for leaf cellulose. It was demonstrated that independent of RH, light-dependent reduction of stomatal conductance (and thus transpiration) and of A(max) can drive the pattern of Delta18O increase with the concomitant decrease of delta13C in the shade crown. The effect of doubling ozone levels on time-integrated stomatal conductance and transpiration as indicated by the combined analysis of Delta18O and delta13C was much lower than the influence caused by the light exposure.

  6. The aquatic vegetation in the Dokka delta, Randsfjorden. Status and assessment of the consequences of the Dokka regulation; Vannvegetasjonen i Dokkadeltaet, Randsfjorden. Status og vurdering av konsekvenser av Dokka-reguleringen

    Energy Technology Data Exchange (ETDEWEB)

    Brandrud, T E; Mjelde, M; Roerslett, B

    1994-08-01

    In connection with regulation of the Dokka river system for hydroelectric power production, the aquatic vegetation of the Dokka delta before and immediately after regulation have been investigated, mainly by means of transect analyses including under water photography. As described in this report, the vegetation was found to be rich in species and luxuriant compared to that of the rest of Randsfjorden and dominated by the species Isoetes setacea, Subularia aquatica, Eleocharis acicularis, Ranunculus reptans and Isoetes lacustris. Due to the regulation, the water drains away from the great shallows in late winter and exposes the vegetation to drought and freeze. The drought keeps the Elodea canadensis in check in the delta. However, because of the very extensive delta shallows the delta experiences ice erosion and removal of fine material. The regulation will probably have relatively little short-term impact on the water vegetation. In the long run, however, regulation may contribute to a somewhat faster over-growing of some delta forms because of reduced flood discharge and reduced mud transport in the delta. 59 refs., 22 figs., 18 tabs.

  7. VALUASI TOTAL EKONOMI HUTAN MANGROVE DI KAWASAN DELTA MAHAKAM KABUPATEN KUTAI KARTANEGARA KALIMANTAN TIMUR

    Directory of Open Access Journals (Sweden)

    Yuyun Wahyuni

    2014-04-01

    Full Text Available Mangrove forest is a tropical coastal vegetation community. The purpose of this study are: to identify the types and functions of the ecosystem of the area of mangrove forest; calculate the total economic value generated by mangrove forests; examine the factors that affect the economic benefits gained at the Mahakam Delta mangrove forest, Kutai regency. Results of this study indicated that there were four dominant types of forests mangrove: rizhopora, avicennia, sonneratia and nypa. They have decreased due to reduced function of mangrove forest area. This result is supported by the calculation of total economic value (TEV in 2012 which amounted to Rp503.071.398 869,2. Factor affecting the economic benefits of mangrove forests in order to remain sustainable in recreational value of travel cost, student employment, the number of dependent and age, while the factors that affect the existence of the mangrove forest are job and income, while the factor that affect the sustainability endemic bekantan are of the income, origin in the region and outside the region.Keywords: Mahakam delta, mangrove forest, TEV

  8. Appearing like a state: Oil companies and local violence in the Niger Delta

    Science.gov (United States)

    Mattner, Mark

    What determines the extent to which communities in the Niger Delta experience violence? The dissertation addresses this question by focusing on the role of multinational oil companies in local governance, where state institutions are weak. The available literature often overlooks this important dimension. Specifically, the dissertation evaluates whether the choice of community relation policies by oil companies accounts for variations in local violence. These policies often include community development projects and attempts at strengthening local institutions. The main hypothesis is that where projects are allocated and implemented through participatory processes, informal institutions are created which substitute for weak local governments and reduce violence. The dissertation tests this contention by comparing four cases which were selected according to differences in their levels of violence. It concludes that the hypothesis is valid only in highly specific circumstances. In most cases, levels of repression and the relationship between companies and local elites are more significant explanations for violence. This is because oil companies and the state continue to rely primarily on repression and co-optation in their relationship with local communities. Community development and corporate social responsibility are secondary concerns. The central implication of this analysis is that a solution to the crisis in the Niger Delta is unlikely to lie in self-regulation and non-binding commitments by corporate actors. More promising approaches are strengthening local governments by ensuring the integrity of local elections and more stringent regulation of oil company conduct.

  9. Nesting ecology of tundra swans on the coastal Yukon-Kuskokwim Delta, Alaska

    Science.gov (United States)

    Babcock, C.A.; Fowler, A.C.; Ely, Craig R.

    2002-01-01

    Nesting ecology of Tundra Swans (Cygnus columbianus columbianus) was studies the Kashunuk River near Old Chevak (61A?26a??N, 165A?27a??W), on the Yukon-Kuskokwim Delta of western Alaska from 1988-2000. Annual variation in snow-melt chronology, nesting phenology, nesting density, clutch size and nest success was examined. The same area (approximately 23 kmA?) was searched each year and nests were found as early as possible in the laying period. Laying initiation dates ranged from 1-27 May and hatch dates from 12 June a?? 4 July among pairs and years of study. The peak arrival of Tundra Swans and the phenology of nest initiation and hatch were highly correlated with the progression of ice and snow melt in spring. Nest density averaged 0.71 kmA? and 89% of nesting pairs hatched at least one egg. Incubation period ranged from 26 to 33 days with a median of 30 days. Clutch size varied significantly among years, driven by a low mean value of 3.4 eggs in 1999. Clutch sizes were generally larger than found in previous investigations on the Yukon-Kuskokwim Delta, and nearly one egg larger than reported for clutches from Alaskaa??s North Slope (=70A?N). There was no indication of reduced clutch size in years of late spring snow melt, although nesting density tended to be lower.

  10. Environmental accounting: A tool for promoting environmental management in the Niger Delta

    Directory of Open Access Journals (Sweden)

    Ph. D. Uwuigne Uwalomwa

    2012-05-01

    Full Text Available Oil exploration and exploitation has over the last four decades impacted disastrously on the socio-physical environment of the Niger Delta oil-bearing communities in Nigeria. This invariably is responsible for the social unrest in the host communities. In response to various pressures by environmental lobby groups, companies have began to realize the need for the integration of environmental reporting practice in their annual report. To this end, this paper studied exploratively the extent to which the introduction of environmental accounting practice will help in bringing about an improved environmental sustainability and an effective environmental management system in the Niger delta region of Nigeria. The paper concludes that the integration and the disclosure of environmental liabilities will to a large extent reduce the social unrest in these areas. This in return will help organizations to maximize the efficient use of their resources, minimize environmental liabilities and demonstrate a good corporate image. The paper therefore recommends that accountants and environmental experts should pool their skills to form a multi-disciplinary team to address environmental issues.

  11. Displacement waves in La2CuO(4-delta) and La(1.85)Sr(0.15)CuO(4-delta)

    Science.gov (United States)

    Kajitani, Tsuyoshi; Onozuka, Takashi; Yamaguchi, Yasuo; Hirabayashi, Makoto; Syono, Yasuhiko

    1987-11-01

    Structural investigation of orthorhombic La2CuO(4-delta) and La(1.85)Sr(0.15)CuO(4-delta) was carried out by means of X-ray and neutron diffraction on the basis of the space group Cmmm. The periodic expansion/contraction type distortion of CuO6 octahedra was found in both orthorhombic compounds. The distortion is nearly one-dimensional in La2CuO(4-delta) but is two-dimensional in La(1.85)Sr(0.15)CuO(4-delta). The existence of a charge-density wave is highly possible in the structures.

  12. Mapping Soil Carbon in the Yukon Kuskokwim River Delta Alaska

    Science.gov (United States)

    Natali, S.; Fiske, G.; Schade, J. D.; Mann, P. J.; Holmes, R. M.; Ludwig, S.; Melton, S.; Sae-lim, N.; Jardine, L. E.; Navarro-Perez, E.

    2017-12-01

    Arctic river deltas are hotspots for carbon storage, occupying 10% of carbon stored in arctic permafrost. The Yukon Kuskokwim (YK) Delta, Alaska is located in the lower latitudinal range of the northern permafrost region in an area of relatively warm permafrost that is particularly vulnerable to warming climate. Active layer depths range from 50 cm on peat plateaus to >100 cm in wetland and aquatic ecosystems. The size of the soil organic carbon pool and vulnerability of the carbon in the YK Delta is a major unknown and is critically important as climate warming and increasing fire frequency may make this carbon vulnerable to transport to aquatic and marine systems and the atmosphere. To characterize the size and distribution of soil carbon pools in the YK Delta, we mapped the land cover of a 1910 km2 watershed located in a region of the YK Delta that was impacted by fire in 2015. The map product was the result of an unsupervised classification using the Weka K Means clustering algorithm implemented in Google's Earth Engine. Inputs to the classification were Worldview2 resolution optical imagery (1m), Arctic DEM (5m), and Sentinel 2 level 1C multispectral imagery, including NDVI, (10 m). We collected 100 soil cores (0-30 cm) from sites of different land cover and landscape position, including moist and dry peat plateaus, high and low intensity burned plateaus, fens, and drained lakes; 13 lake sediment cores (0-50 cm); and 20 surface permafrost cores (to 100 cm) from burned and unburned peat plateaus. Active layer and permafrost soils were analyzed for organic matter content, soil moisture content, and carbon and nitrogen pools (30 and 100 cm). Soil carbon content varied across the landscape; average carbon content values for lake sediments were 12% (5- 17% range), fens 26% (9-44%), unburned peat plateaus 41% (34-44%), burned peat plateaus 19% (7-34%). These values will be used to estimate soil carbon pools, which will be applied to the spatial extent of each

  13. Cholinergic axon length reduced by 300 meters in the brain of an Alzheimer mouse model

    DEFF Research Database (Denmark)

    Nikolajsen, Gitte; Jensen, Morten Skovgaard; West, Mark J.

    2011-01-01

    Modern stereological techniques have been used to show that the total length of the cholinergic fibers in the cerebral cortex of the APPswe/PS1deltaE9 mouse is reduced by almost 300 meters at 18 months of age and has a nonlinear relationship to the amount of transgenetically-induced amyloidosis. ....... These data provide rigorous quantitative morphological evidence that Alzheimer's-like amyloidosis affects the axons of the cholinergic enervation of the cerebral cortex....

  14. Effect of environmental change on the morphology of tidally influenced deltas over multi-decadal timescale

    Science.gov (United States)

    Angamuthu, Balaji; Darby, Stephen; Nicholls, Robert

    2017-04-01

    An understanding of the geomorphological processes affecting deltas is essential to improve our understanding of the risks that deltas face, especially as human impacts are likely to intensify in the future. Unfortunately, there is limited reliable data on river deltas, meaning that the task of demonstrating the links between morphodynamic and environmental change is challenging. This presentation aims to answer the questions of how delta morphology evolves over multi-decadal timescales under multiple drivers, focussing on tidally-influenced deltas, as some of these, such as the Ganges-Brahmaputra-Meghna (GBM) delta are heavily populated. A series of idealised model simulations over 102 years were used to explore the influence of three key drivers on delta morphodynamics, both individually and together: (i) varying combinations of water and sediment discharges from the upstream catchment, (ii) varying rates of relative sea-level rise (RSLR), and (iii) selected human interventions within the delta, such as polders, cross-dams and changing land cover. Model simulations revealed that delta progradation rates are more sensitive to variations in water discharge than variations in fluvial sediment supply. Unlike mere aggradation during RSLR, the delta front experienced aggradational progradation due to tides. As expected, the area of the simulated sub-aerial delta increases with increasing sediment discharge, but decreases with increasing water discharge. But, human modifications are important. For example, the sub-aerial delta shrinks with increasing RSLR, but it does not when the sub-aerial delta is polderised, provided the polders are restricted from erosion. However, the polders are vulnerable to flooding as they lose relative elevation and can make the delta building process unsustainable. Cross-dams built to steer zones of land accretion within the delta accomplish their local goal, but may not result in net land gain at the scale of the delta. Applying these

  15. Modern Geophysical Techniques for Constructing a 3D Geological Model on the Nile Delta, Egypt

    OpenAIRE

    Barakat, Moataz Khairy Ahmad

    2010-01-01

    The Nile Delta can be considered the earliest known delta in the world. It was described by Herodotus in the 5th Century AC. The Nile Delta (Ta-Mehet) in Hieroglyphic language means the land of the estuary water. It is one of the oldest intensely cultivated areas on the earth. The Nile Delta is illustrated to be an arcuate delta (arcshaped), as it resembles a triangle or lotus flower when seen from above. The name has been derived from the letter Thelta of the Greek alphabet. In comparison to...

  16. Investigations of (Delta)14C, (delta)13C, and (delta)15N in vertebrae of white shark (Carcharodon carcharias) from the eastern North Pacific Ocean

    Energy Technology Data Exchange (ETDEWEB)

    Kerr, L A; Andrews, A H; Cailliet, G M; Brown, T A; Coale, K H

    2006-06-08

    The white shark (Carcharodon carcharias) has a complex life history that is characterized by large scale movements and a highly variable diet. Estimates of age and growth for the white shark from the eastern North Pacific Ocean indicate they have a slow growth rate and a relatively high longevity. Age, growth, and longevity estimates useful for stock assessment and fishery models, however, require some form of validation. By counting vertebral growth band pairs, ages can be estimated, but because not all sharks deposit annual growth bands and many are not easily discernable, it is necessary to validate growth band periodicity with an independent method. Radiocarbon ({sup 14}C) age validation uses the discrete {sup 14}C signal produced from thermonuclear testing in the 1950s and 1960s that is retained in skeletal structures as a time-specific marker. Growth band pairs in vertebrae, estimated as annual and spanning the 1930s to 1990s, were analyzed for {Delta}{sup 14}C and stable carbon and nitrogen isotopes ({delta}{sup 13}C and {delta}{sup 15}N). The aim of this study was to evaluate the utility of {sup 14}C age validation for a wide-ranging species with a complex life history and to use stable isotope measurements in vertebrae as a means of resolving complexity introduced into the {sup 14}C chronology by ontogenetic shifts in diet and habitat. Stable isotopes provided useful trophic position information; however, validation of age estimates was confounded by what may have been some combination of the dietary source of carbon to the vertebrae, large-scale movement patterns, and steep {sup 14}C gradients with depth in the eastern North Pacific Ocean.

  17. Stepwise morphological evolution of the active Yellow River (Huanghe) delta lobe (1976-2013): Dominant roles of riverine discharge and sediment grain size

    Science.gov (United States)

    Wu, Xiao; Bi, Naishuang; Xu, Jingping; Nittrouer, Jeffrey A.; Yang, Zuosheng; Saito, Yoshiki; Wang, Houjie

    2017-09-01

    m; however, the delta suffered net erosion because of the insufficient sediment supply (0.11 Gt/yr). In the most recent stage (2002 - 2013), the intensive scouring of the lower river channel induced by the dam regulation provided relatively coarser sediment, which effectively reduced the critical sediment load to 0.06 Gt/yr, much lower than the corresponding sediment load at Lijin station ( 0.16 Gt/yr). Consequently, the subaerial Yellow River delta transitioned to a slight accretion phase. Overall, the evolution of the active Yellow River delta is highly correlated to riverine water and sediment discharge. The sediment supply for keeping the subaerial delta stability is inconstant and varying with the river channel morphology and sediment grain size. We conclude that the human-impacted riverine sediment discharge and grain-size composition play dominant roles in the stepwise morphological evolution of the active delta lobe.

  18. Numerical study on a canonized Hamiltonian system representing reduced magnetohydrodynamics and its comparison with two-dimensional Euler system

    OpenAIRE

    Kaneko, Yuta; Yoshida, Zensho

    2014-01-01

    Introducing a Clebsch-like parameterization, we have formulated a canonical Hamiltonian system on a symplectic leaf of reduced magnetohydrodynamics. An interesting structure of the equations is in that the Lorentz-force, which is a quadratic nonlinear term in the conventional formulation, appears as a linear term -{\\Delta}Q, just representing the current density (Q is a Clebsch variable, and {\\Delta} is the two-dimensional Laplacian); omitting this term reduces the system into the two-dimensi...

  19. Casscf/ci Calculations for First Row Transition Metal Hydrides - the TIH(4-PHI), VH(5-DELTA), CRH(6-SIGMA-PLUS), MNH(7-SIGMA-PLUS), FEH(4,6-DELTA) and NIH(2-DELTA) States

    Science.gov (United States)

    Walch, S. P.; Bauschlicher, C. W., Jr.

    1983-04-01

    Calculations are performed for the predicted ground states of TiH(4-phi), VH(5-delta), CrH(6-sigma-plus), MnH(7-sigma-plus), Fett(4,6-delta) and NiH(2-delta). For FeH both the 6-delta and 4-delta states are studied, since both are likely candidates for the ground state. The ground state symmetries are predicted based on a combination of atomic coupling arguments and coupling of 4s(2)3d(n) and 4s(1)3d(n+1) terms in the molecular system. Electron correlation is included by a CASSCF/CI (SD) treatment. The CASSCF includes near-degeneracy effects, while correlation of the 3d electrons in included at the CI level.

  20. On new physics in $\\Delta \\Gamma_d$

    CERN Document Server

    Bobeth, Christoph; Lenz, Alexander; Pecjak, Ben; Tetlalmatzi-Xolocotzi, Gilberto

    2014-06-09

    Motivated by the recent measurement of the dimuon asymmetry by the D{\\O} collaboration, which could be interpreted as an enhanced decay rate difference in the neutral $B_d$-meson system, we investigate the possible size of new-physics contributions to $\\Delta \\Gamma_d$. In particular, we perform model-independent studies of non-standard effects associated to the dimension-six current-current operators $(\\bar{d} p)(\\bar p^{\\hspace{0.25mm}\\prime} b)$ with $p,p^\\prime= u,c$ as well as $(\\bar{d}b) (\\bar\\tau\\tau)$. In both cases we find that for certain flavour or Lorentz structures of the operators sizable deviations of $\\Delta \\Gamma_d$ away from the Standard Model expectation cannot be excluded in a model-independent fashion.

  1. HDVDB: a data warehouse for hepatitis delta virus.

    Science.gov (United States)

    Singh, Sarita; Gupta, Sunil Kumar; Nischal, Anuradha; Pant, Kamlesh Kumar; Seth, Prahlad Kishore

    2015-01-01

    Hepatitis Delta Virus (HDV) is an RNA virus and causes delta hepatitis in humans. Although a lot of data is available for HDV, but retrieval of information is a complicated task. Current web database 'HDVDB' provides a comprehensive web-resource for HDV. The database is basically concerned with basic information about HDV and disease caused by this virus, genome structure, pathogenesis, epidemiology, symptoms and prevention, etc. Database also supplies sequence data and bibliographic information about HDV. A tool 'siHDV Predict' to design the effective siRNA molecule to control the activity of HDV, is also integrated in database. It is a user friendly information system available at public domain and provides annotated information about HDV for research scholars, scientists, pharma industry people for further study.

  2. Methods for deconvolving sparse positive delta function series

    International Nuclear Information System (INIS)

    Trussell, H.J.; Schwalbe, L.A.

    1981-01-01

    Sparse delta function series occur as data in many chemical analyses and seismic methods. These original data are often sufficiently degraded by the recording instrument response that the individual delta function peaks are difficult to distinguish and measure. A method, which has been used to measure these peaks, is to fit a parameterized model by a nonlinear least-squares fitting algorithm. The deconvolution approaches described have the advantage of not requiring a parameterized point spread function, nor do they expect a fixed number of peaks. Two new methods are presented. The maximum power technique is reviewed. A maximum a posteriori technique is introduced. Results on both simulated and real data by the two methods are presented. The characteristics of the data can determine which method gives superior results. 5 figures

  3. Flood mitigation strategies for the Red River Delta

    International Nuclear Information System (INIS)

    Hansson, K.; Ekenberg, L.

    2002-01-01

    The increase of natural disasters and especially floods are escalating economical losses. Governments of both developed and developing countries are therefore concerned with increasing post-disaster liabilities in aiding recovery, repairing infrastructure damage and compensation of victims. In particular, governments of developing countries are ill prepared to cover the financial losses of disasters. Moreover, they often experience difficulties in raising funds for the recovery process. In this article, we identify possible policy strategies for coping with complex environmental and social decisions with flood risk involved; using The Red River Delta in Vietnam as a case for investigating various strategies. The paper is concluded with an outline of a model used for policy scenario simulations as well as some very preliminary results from evaluation of three possible policy strategies for The Red River Delta. (author)

  4. Measuring $CP$ violation with $\\Delta A_{CP}$ at LHCb

    CERN Document Server

    Pearce, Alex

    2014-01-01

    The control of systematic uncertainties is a key component of many analyses performed at the Large Hadron Collider, and will only become more important as more data are taken during Run II. Many of the CP measurements performed using the LHCb detector have statistical precisions below the per cent level, and so particular care must be taken in this area. One technique for dealing with the various production and detection asymmetries which can mask the physics asymmetry of interest, and increase the measurement’s systematic uncertainty, is $\\Delta A_{CP}$ . The application of $\\Delta A_{CP}$ in three separate LHCb analyses of $D^{0}$ and $\\Lambda_{b}^{0}$ decays will be discussed, along with prospects for applying the technique to $\\Lambda_{c}^{+}$ decays.

  5. The Legal Status of the Danube Delta Biosphere Reservation

    Directory of Open Access Journals (Sweden)

    Florica Brasoveanu

    2012-05-01

    Full Text Available In recent years the world has become aware that natural resources are not inexhaustible, that manyspecies are threatened with extinction and that is is necessary to strive for judicious use of natural resources tofulfill the needs of the present without compromising the ability of future generations to meet their needs(principle of sustainable development. To conserve species and habitats protected areas have beenestablished worldwide. The protected area is a geographically defined area, with rare natural elements and / orendangered species, regulated and managed in order to achieve specific conservation objectives. Althoughranked Europe's second in size (after the Volga River and the 20th in the world, because of the rich landscapeand wildlife, with the birds ranked most important, the Danube Delta has a very special interest scientificallyas it is a natural laboratory of forming delta, tourism and economic ecosystems, through its renewable naturalresources of which the most important resources are living aquatic resources.

  6. D2 Delta Robot Structural Design and Kinematics Analysis

    Science.gov (United States)

    Yang, Xudong; wang, Song; Dong, Yu; Yang, Hai

    2017-12-01

    In this paper, a new type of Delta robot with only two degrees of freedom is proposed on the basis of multi - degree - of - freedom delta robot. In order to meet our application requirements, we have carried out structural design and analysis of the robot. Through SolidWorks modeling, combined with 3D printing technology to determine the final robot structure. In order to achieve the precise control of the robot, the kinematics analysis of the robot was carried out. The SimMechanics toolbox of MATLAB is used to establish the mechanism model, and the kinematics mathematical model is used to simulate the robot motion control in Matlab environment. Finally, according to the design mechanism, the working space of the robot is drawn by the graphic method, which lays the foundation for the motion control of the subsequent robot.

  7. The delta18O composition of Antarctic coastal current waters

    International Nuclear Information System (INIS)

    Frew, R.; Heywood, K.; Dennis, P.

    1997-01-01

    The varying proportions of 18 O to 16 O in sea water provide an oceanographic trace like salinity, but with an extra degree of freedom: salt is a tracer for the oceanic fluid, whereas the isotopic composition is a tracer specifically for the water component of that fluid. Hydrogen and oxygen isotopes are the variables most intimately related to the water component in the sea, therefore thay furnish a direct link to the water in the atmosphere and on continents and to the precipitation cycle which caused the salinity changes. The ratio of 18 O to 16 O (delta 18 O) ot waters is a powerful tracer in polar regions where sea and glacial ice processes decouple delta 18 O from salinity. Here we present observations from a significant but relatively unexplored component of the Southern Ocean current system, the Antarctic Coastal Current, and its associated Antarctic Slope Front. (author)

  8. A pilot project: Antioch Delta Cove, Antioch, California

    International Nuclear Information System (INIS)

    Minder, M.

    1994-01-01

    The project involves the restoration of the Hickmott cannery site, comprising approximately 15 acres (three five acre parcels) located on the Delta in inter-city Antioch. Hickmott Foods, Inc., operated a fruit and vegetable cannery between 1905 and the early 1970's, during which time tomato skins, peach and apricot pits, and asparagus butts were discharged on the site. The decaying fruit pits have caused cyanide contamination. Additionally, the site contains some petroleum hydrocarbon contamination as well as gypsum board contamination, apparently from nearby manufacturing operations. The Antioch Delta Cove Pilot shows how interested parties can work together to clean up contaminated sites and use the clean up process to stimulate technology transfer. The Antioch project is a blueprint that can be replicated at other sites across California

  9. Development of sunflower germplasm with high delta-tocopherol content

    OpenAIRE

    Velasco L.; Pérez-Vich B.; Fernández-Martínez J.M.

    2004-01-01

    Tocopherols are the main compounds with antioxidant activity in oilseeds Sunflower seeds contain predominantly alpha-tocopherol, which accounts for more than 90% of the total tocopherols in the seeds. This tocopherol derivative possesses a maximum vitamin E or in vivo antioxidant activity, but it exerts a minimum in vitro protective action in oils and food containing them. Other tocopherol derivatives such as beta-, gamma-, and delta-tocopherol are more powerful antioxidants than alpha-tocoph...

  10. Empirical P-L-C relations for delta Scuti stars

    International Nuclear Information System (INIS)

    Gupta, S.K.

    1978-01-01

    Separate P-L-C relations have been empirically derived by sampling the delta Scuti stars according to their pulsation modes. The results based on these relations have been compared with those estimated from the model based P-L-C relations and the other existing empirical P-L-C relations. It is found that a separate P-L-C relation for each pulsation mode provides a better correspondence with observations. (Auth.)

  11. Smilansky-Solomyak model with a delta '-interaction

    Czech Academy of Sciences Publication Activity Database

    Exner, Pavel; Lipovský, J.

    2018-01-01

    Roč. 382, č. 18 (2018), s. 1207-1213 ISSN 0375-9601 R&D Projects: GA ČR GA17-01706S Institutional support: RVO:61389005 Keywords : Smilansky-Solomyak model * delta '-interaction * spectral theory Subject RIV: BE - Theoretical Physics OBOR OECD: Atomic, molecular and chemical physics ( physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect) Impact factor: 1.772, year: 2016

  12. Process connectivity in a naturally prograding river delta

    Science.gov (United States)

    Sendrowski, Alicia; Passalacqua, Paola

    2017-03-01

    River deltas are lowland systems that can display high hydrological connectivity. This connectivity can be structural (morphological connections), functional (control of fluxes), and process connectivity (information flow from system drivers to sinks). In this work, we quantify hydrological process connectivity in Wax Lake Delta, coastal Louisiana, by analyzing couplings among external drivers (discharge, tides, and wind) and water levels recorded at five islands and one channel over summer 2014. We quantify process connections with information theory, a branch of mathematics concerned with the communication of information. We represent process connections as a network; variables serve as network nodes and couplings as network links describing the strength, direction, and time scale of information flow. Comparing process connections at long (105 days) and short (10 days) time scales, we show that tides exhibit daily synchronization with water level, with decreasing strength from downstream to upstream, and that tides transfer information as tides transition from spring to neap. Discharge synchronizes with water level and the time scale of its information transfer compares well to physical travel times through the system, computed with a hydrodynamic model. Information transfer and physical transport show similar spatial patterns, although information transfer time scales are larger than physical travel times. Wind events associated with water level setup lead to increased process connectivity with highly variable information transfer time scales. We discuss the information theory results in the context of the hydrologic behavior of the delta, the role of vegetation as a connector/disconnector on islands, and the applicability of process networks as tools for delta modeling results.

  13. Reactive Flow Control of Delta Wing Vortex (Postprint)

    Science.gov (United States)

    2006-08-01

    wing aircraft. A substantial amount of research has been dedicated to the control of aerodynamic flows using both passive and active control mechanisms...Passive vortex control devices such as vortex generators and winglets attach to the wing and require no energy input. Passive vortex control...leading edges is also effective for changing the aerodynamic characteristics of delta wings [2] [3]. Gutmark and Guillot [5] proposed controlling

  14. Des drones survolant le delta | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    25 nov. 2016 ... Photo prise par un drone survolant la ville de Fuvemeh. Appeaning-Addo et al. 2015. Les vagues balayant le rivage de Fuvemeh, une ville ghanéenne qui est située près du delta du fleuve Volta et que menacent les inondations et l'érosion des côtes. Par Brian Owens, Canadian Geographic. La région du ...

  15. Delta Learning Rule for the Active Sites Model

    OpenAIRE

    Lingashetty, Krishna Chaithanya

    2010-01-01

    This paper reports the results on methods of comparing the memory retrieval capacity of the Hebbian neural network which implements the B-Matrix approach, by using the Widrow-Hoff rule of learning. We then, extend the recently proposed Active Sites model by developing a delta rule to increase memory capacity. Also, this paper extends the binary neural network to a multi-level (non-binary) neural network.

  16. Stringent tests of constrained Minimal Flavor Violation through {Delta}F=2 transitions

    Energy Technology Data Exchange (ETDEWEB)

    Buras, Andrzej J. [TUM-IAS, Garching (Germany); Girrbach, Jennifer [TUM, Physik Department, Garching (Germany)

    2013-09-15

    between F{sub B{sub s}} {radical}(B{sub B{sub s}}) and F{sub B{sub d}} {radical}(B{sub B{sub d}}), vertical stroke V{sub cb} vertical stroke, vertical stroke V{sub ub} vertical stroke and {gamma} that should be tested in the coming years. Typically F{sub B{sub s}} {radical}(B{sub B{sub s}}) and F{sub B{sub d}} {radical}(B{sub B{sub d}}) have to be lower than their present lattice values, while vertical stroke V{sub cb} vertical stroke has to be higher than its tree-level determination, with a significance depending on the evolution of their errors. Within the SM this would imply values for B(K{sup +} {yields} {pi}{sup +}{nu} anti {nu}) and B(K{sub L} {yields} {pi}{sup 0}{nu} anti {nu}) that are typically larger by (15-20) % than those presently quoted in the literature. The region in the space of these three parameters allowed by CMFV indicates tensions in this class of models and hints for the presence of new sources of flavor violation and/or new local operators in {Delta}F=2 data that are strongly suppressed in these models. As a byproduct we propose to reduce the present uncertainty in the charm contribution to {epsilon}{sub K} by using the experimental value of {Delta}M{sub K}. (orig.)

  17. Pen Branch Delta and Savannah River Swamp Hydraulic Model

    International Nuclear Information System (INIS)

    Chen, K.F.

    1999-01-01

    The proposed Savannah River Site (SRS) Wetlands Restoration Project area is located in Barnwell County, South Carolina on the southwestern boundary of the SRS Reservation. The swamp covers about 40.5 km2 and is bounded to the west and south by the Savannah River and to the north and east by low bluffs at the edge of the Savannah River floodplain. Water levels within the swamp are determined by stage along the Savannah River, local drainage, groundwater seepage, and inflows from four tributaries, Beaver Dam Creek, Fourmile Branch, Pen Branch, and Steel Creek. Historic discharges of heated process water into these tributaries scoured the streambed, created deltas in the adjacent wetland, and killed native vegetation in the vicinity of the delta deposits. Future releases from these tributaries will be substantially smaller and closer to ambient temperatures. One component of the proposed restoration project will be to reestablish indigenous wetland vegetation on the Pen Branch delta that covers about 1.0 km2. Long-term predictions of water levels within the swamp are required to determine the characteristics of suitable plants. The objective of the study was to predict water levels at various locations within the proposed SRS Wetlands Restoration Project area for a range of Savannah River flows and regulated releases from Pen Branch. TABS-MD, a United States Army Corps of Engineer developed two-dimensional finite element open channel hydraulic computer code, was used to model the SRS swamp area for various flow conditions

  18. Sevoflurane Induces Coherent Slow-Delta Oscillations in Rats

    Directory of Open Access Journals (Sweden)

    Jennifer A. Guidera

    2017-07-01

    Full Text Available Although general anesthetics are routinely administered to surgical patients to induce loss of consciousness, the mechanisms underlying anesthetic-induced unconsciousness are not fully understood. In rats, we characterized changes in the extradural EEG and intracranial local field potentials (LFPs within the prefrontal cortex (PFC, parietal cortex (PC, and central thalamus (CT in response to progressively higher doses of the inhaled anesthetic sevoflurane. During induction with a low dose of sevoflurane, beta/low gamma (12–40 Hz power increased in the frontal EEG and PFC, PC and CT LFPs, and PFC–CT and PFC–PFC LFP beta/low gamma coherence increased. Loss of movement (LOM coincided with an abrupt decrease in beta/low gamma PFC–CT LFP coherence. Following LOM, cortically coherent slow-delta (0.1–4 Hz oscillations were observed in the frontal EEG and PFC, PC and CT LFPs. At higher doses of sevoflurane sufficient to induce loss of the righting reflex, coherent slow-delta oscillations were dominant in the frontal EEG and PFC, PC and CT LFPs. Dynamics similar to those observed during induction were observed as animals emerged from sevoflurane anesthesia. We conclude that the rat is a useful animal model for sevoflurane-induced EEG oscillations in humans, and that coherent slow-delta oscillations are a correlate of sevoflurane-induced behavioral arrest and loss of righting in rats.

  19. Nitrous oxide-induced slow and delta oscillations.

    Science.gov (United States)

    Pavone, Kara J; Akeju, Oluwaseun; Sampson, Aaron L; Ling, Kelly; Purdon, Patrick L; Brown, Emery N

    2016-01-01

    Switching from maintenance of general anesthesia with an ether anesthetic to maintenance with high-dose (concentration >50% and total gas flow rate >4 liters per minute) nitrous oxide is a common practice used to facilitate emergence from general anesthesia. The transition from the ether anesthetic to nitrous oxide is associated with a switch in the putative mechanisms and sites of anesthetic action. We investigated whether there is an electroencephalogram (EEG) marker of this transition. We retrospectively studied the ether anesthetic to nitrous oxide transition in 19 patients with EEG monitoring receiving general anesthesia using the ether anesthetic sevoflurane combined with oxygen and air. Following the transition to nitrous oxide, the alpha (8-12 Hz) oscillations associated with sevoflurane dissipated within 3-12 min (median 6 min) and were replaced by highly coherent large-amplitude slow-delta (0.1-4 Hz) oscillations that persisted for 2-12 min (median 3 min). Administration of high-dose nitrous oxide is associated with transient, large amplitude slow-delta oscillations. We postulate that these slow-delta oscillations may result from nitrous oxide-induced blockade of major excitatory inputs (NMDA glutamate projections) from the brainstem (parabrachial nucleus and medial pontine reticular formation) to the thalamus and cortex. This EEG signature of high-dose nitrous oxide may offer new insights into brain states during general anesthesia. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  20. Structural Style and Lead Identification, Northern Depobelt, Niger Delta, Nigeria

    International Nuclear Information System (INIS)

    Ola, P. S.; Adekoya, J. A.

    2003-01-01

    By interpreting biofacies data, wire line log and grid of 2D seismic sections in an integrated manner in some portions of the northern depobelt, Niger delta, the sequence stratigraphic framework of the area was established. This enabled the structural style and genetic sequences of the area to be inferred. Results showed that the depobelt could be I subdivided into minibasins that trend in a NW SE direction and are bounded by synthetic faults in the proximal end and shale diapers in the distal end. All the exploration wells in the area of study, which were drilled on structural highs and were very close to the synthetic faults, turned out to be dry whereas the synclinal lows that resulted from local deposition of sands of the first genetic sequences in each of the minibasins could contain hydrocarbon. Such areas of synclinal lows are hereby proposed, as lead in this study. The intervals are untested and occur faraway from existing wells. By projection the geochemical data of well Oben-1 in the area suggest that the intervals fall within the oil generative window. Characteristic seismic reflection termination patterns, which are predominantly down laps and on laps suggest existence of structural closure for hydrocarbon accumulation within the synclinal lows. This study therefore recommends a reappraisal of these leads using a more focused 3D seismic study. The northern delta depobelt is less risky and inexpensive for oil exploration and exploitation compared with the offshore Niger delta that is gaining more prominence