Sun in the Epoch ``LOWERED'' Solar Activity: the Comparative Analysis of the Current 24 Solar Cycle and Past Authentic Low Cycles

Science.gov (United States)

Vitaly, Ishkov

A reliable series of the relative numbers of sunspots (14 solar cycles ‒ 165 years) it leads to the only scenario of solar activity cycles - to the alternation of epochs of “increased” (18 ‒ 22 cycles of solar activity) and “lowered” (12 ‒ 16 and 24 ‒ ...) solar activity with the periods of solar magnetic field reconstruction in solar zone of the sunspots formation (11, 12, 23) from one epoch to another. The regime of the produce of magnetic field significantly changes in these periods, providing to the subsequent 5 cycles the stable conditions of solar activity. Space solar research made it possible to sufficiently fully investigate characteristics and parameters of the solar cycles for the epoch of “increased” (20 ‒ 22 cycles) solar activity and period of the reconstruction (22 ‒ 23 cycles) to the epoch of “lowered” solar activity (24 ‒ ... cycles). In this scenario 24 solar cycle is the first solar cycle of the second epoch of “lowered” solar activity. Therefore his development and characteristics roughly must be described in the context of the low solar cycles development (12, 14, and 16). In the current solar cycle the sunspot-forming activity is lowered, the average areas of the sunspot groups correspond to values for epoch of “lowered “solar activity, average magnetic field in the umbra of sunspots was reduced approximately to 700 gauss, and for this time was observed only 4 very large sunspot groups (≥1500 mvh). Flare activity substantially was lowered: for the time of the current solar cycle development it was occurrence of M-class flares M - 368, class X - 32, from which only 2 solar flares of class X> 5. Solar proton events are observed predominantly small intensity; but only 5 from them were the intensity of ≥100 pfu (S2) and 4 - ≥1000 pfu (S3). The first five years of the 24 cycle evolution confirm this assumption and the possibility to give the qualitative forecast of his evolution and development of the

Senescence gives insights into the morphogenetic evolution of anamniotes

Directory of Open Access Journals (Sweden)

Éric Villiard

2017-06-01

Full Text Available Senescence represents a mechanism to avoid undesired cell proliferation that plays a role in tumor suppression, wound healing and embryonic development. In order to gain insight on the evolution of senescence, we looked at its presence in developing axolotls (urodele amphibians and in zebrafish (teleost fish, which are both anamniotes. Our data indicate that cellular senescence is present in various developing structures in axolotls (pronephros, olfactory epithelium of nerve fascicles, lateral organs, gums and in zebrafish (epithelium of the yolk sac and in the lower part of the gut. Senescence was particularly associated with transient structures (pronephros in axolotls and yolk sac in zebrafish suggesting that it may play a role in the elimination of these tissues. Our data supports the notion that cellular senescence evolved early in vertebrate evolution to influence embryonic development.

Identifying individual sleep apnea/hypoapnea epochs using smartphone-based pulse oximetry.

Science.gov (United States)

Garde, Ainara; Dekhordi, Parastoo; Ansermino, J Mark; Dumont, Guy A

2016-08-01

Sleep apnea, characterized by frequent pauses in breathing during sleep, poses a serious threat to the healthy growth and development of children. Polysomnography (PSG), the gold standard for sleep apnea diagnosis, is resource intensive and confined to sleep laboratories, thus reducing its accessibility. Pulse oximetry alone, providing blood oxygen saturation (SpO2) and blood volume changes in tissue (PPG), has the potential to identify children with sleep apnea. Thus, we aim to develop a tool for at-home sleep apnea screening that provides a detailed and automated 30 sec epoch-by-epoch sleep apnea analysis. We propose to extract features characterizing pulse oximetry (SpO2 and pulse rate variability [PRV], a surrogate measure of heart rate variability) to create a multivariate logistic regression model that identifies epochs containing apnea/hypoapnea events. Overnight pulse oximetry was collected using a smartphone-based pulse oximeter, simultaneously with standard PSG from 160 children at the British Columbia Children's hospital. The sleep technician manually scored all apnea/hypoapnea events during the PSG study. Based on these scores we labeled each epoch as containing or not containing apnea/hypoapnea. We randomly divided the subjects into training data (40%), used to develop the model applying the LASSO method, and testing data (60%), used to validate the model. The developed model was assessed epoch-by-epoch for each subject. The test dataset had a median area under the receiver operating characteristic (ROC) curve of 81%; the model provided a median accuracy of 74% sensitivity of 75%, and specificity of 73% when using a risk threshold similar to the percentage of apnea/hypopnea epochs. Thus, providing a detailed epoch-by-epoch analysis with at-home pulse oximetry alone is feasible with accuracy, sensitivity and specificity values above 73% However, the performance might decrease when analyzing subjects with a low number of apnea/hypoapnea events.

Faint Object Detection in Multi-Epoch Observations via Catalog Data Fusion

Energy Technology Data Exchange (ETDEWEB)

Budavári, Tamás; Szalay, Alexander S. [Department of Physics and Astronomy, The Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Loredo, Thomas J. [Cornell Center for Astrophysics and Planetary Science, Cornell University, Ithaca, NY 14853 (United States)

2017-03-20

Astronomy in the time-domain era faces several new challenges. One of them is the efficient use of observations obtained at multiple epochs. The work presented here addresses faint object detection and describes an incremental strategy for separating real objects from artifacts in ongoing surveys. The idea is to produce low-threshold single-epoch catalogs and to accumulate information across epochs. This is in contrast to more conventional strategies based on co-added or stacked images. We adopt a Bayesian approach, addressing object detection by calculating the marginal likelihoods for hypotheses asserting that there is no object or one object in a small image patch containing at most one cataloged source at each epoch. The object-present hypothesis interprets the sources in a patch at different epochs as arising from a genuine object; the no-object hypothesis interprets candidate sources as spurious, arising from noise peaks. We study the detection probability for constant-flux objects in a Gaussian noise setting, comparing results based on single and stacked exposures to results based on a series of single-epoch catalog summaries. Our procedure amounts to generalized cross-matching: it is the product of a factor accounting for the matching of the estimated fluxes of the candidate sources and a factor accounting for the matching of their estimated directions. We find that probabilistic fusion of multi-epoch catalogs can detect sources with similar sensitivity and selectivity compared to stacking. The probabilistic cross-matching framework underlying our approach plays an important role in maintaining detection sensitivity and points toward generalizations that could accommodate variability and complex object structure.

Faint Object Detection in Multi-Epoch Observations via Catalog Data Fusion

International Nuclear Information System (INIS)

Budavári, Tamás; Szalay, Alexander S.; Loredo, Thomas J.

2017-01-01

Astronomy in the time-domain era faces several new challenges. One of them is the efficient use of observations obtained at multiple epochs. The work presented here addresses faint object detection and describes an incremental strategy for separating real objects from artifacts in ongoing surveys. The idea is to produce low-threshold single-epoch catalogs and to accumulate information across epochs. This is in contrast to more conventional strategies based on co-added or stacked images. We adopt a Bayesian approach, addressing object detection by calculating the marginal likelihoods for hypotheses asserting that there is no object or one object in a small image patch containing at most one cataloged source at each epoch. The object-present hypothesis interprets the sources in a patch at different epochs as arising from a genuine object; the no-object hypothesis interprets candidate sources as spurious, arising from noise peaks. We study the detection probability for constant-flux objects in a Gaussian noise setting, comparing results based on single and stacked exposures to results based on a series of single-epoch catalog summaries. Our procedure amounts to generalized cross-matching: it is the product of a factor accounting for the matching of the estimated fluxes of the candidate sources and a factor accounting for the matching of their estimated directions. We find that probabilistic fusion of multi-epoch catalogs can detect sources with similar sensitivity and selectivity compared to stacking. The probabilistic cross-matching framework underlying our approach plays an important role in maintaining detection sensitivity and points toward generalizations that could accommodate variability and complex object structure.

QSO evolution in the interaction model

International Nuclear Information System (INIS)

De Robertis, M.

1985-01-01

QSO evolution is investigated according to the interaction hypothesis described most recently by Stockton (1982), in which activity results from an interaction between two galaxies resulting in the transfer of gas onto a supermassive black hole (SBH) at the center of at least one participant. Explicit models presented here for interactions in cluster environments show that a peak QSO population can be formed in this way at zroughly-equal2--3, with little activity prior to this epoch. Calculated space densities match those inferred from observations for this epoch. Substantial density evolution is expected in such models, since, after virialization, conditions in the cores of rich clusters lead to the depletion of gas-rich systems through ram-pressure stripping. Density evolution parameters of 6--12 are easily accounted for. At smaller redshifts, however, QSOs should be found primarily in poor clusters or groups. Probability estimates provided by this model are consistent with local estimates for the observed number of QSOs per interaction. Significant luminosity-dependent evolution might also be expected in these models. It is suggested that the mean SBH mass increases with lookback time, leading to a statistical brightening with redshift. Undoubtedly, both forms of evolution contribute to the overall QSO luminosity function

Stochastic evolution of cosmological parameters in the early universe

Indian Academy of Sciences (India)

We develop a stochastic formulation of cosmology in the early universe, after considering the scatter in the redshift-apparent magnitude diagram in the early epochs as an observational evidence for the non-deterministic evolution of early universe. We consider the stochastic evolution of density parameter in the early ...

New Insights about Enzyme Evolution from Large Scale Studies of Sequence and Structure Relationships*

Science.gov (United States)

Brown, Shoshana D.; Babbitt, Patricia C.

2014-01-01

Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfamilies, each representing a large set of sequences that evolved from a common ancestor and that retain conserved features of their structures and active sites. Using several examples, we describe the different structural strategies nature has used to evolve new reaction and substrate specificities in each unique superfamily. The results provide insight about enzyme evolution that is not easily obtained from studies of one or only a few enzymes. PMID:25210038

Systematic Uncertainties in Black Hole Masses Determined from Single Epoch Spectra

DEFF Research Database (Denmark)

Denney, Kelly D.; Peterson, Bradley M.; Dietrich, Matthias

2008-01-01

We explore the nature of systematic errors that can arise in measurement of black hole masses from single-epoch spectra of active galactic nuclei (AGNs) by utilizing the many epochs available for NGC 5548 and PG1229+204 from reverberation mapping databases. In particular, we examine systematics due...

IslandFAST: A Semi-numerical Tool for Simulating the Late Epoch of Reionization

Energy Technology Data Exchange (ETDEWEB)

Xu, Yidong; Chen, Xuelei [Key Laboratory for Computational Astrophysics, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Yue, Bin [National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China)

2017-08-01

We present the algorithm and main results of our semi-numerical simulation, islandFAST, which was developed from 21cmFAST and designed for the late stage of reionization. The islandFAST simulation predicts the evolution and size distribution of the large-scale underdense neutral regions (neutral islands), and we find that the late Epoch of Reionization proceeds very fast, showing a characteristic scale of the neutral islands at each redshift. Using islandFAST, we compare the impact of two types of absorption systems, i.e., the large-scale underdense neutral islands versus small-scale overdense absorbers, in regulating the reionization process. The neutral islands dominate the morphology of the ionization field, while the small-scale absorbers dominate the mean-free path of ionizing photons, and also delay and prolong the reionization process. With our semi-numerical simulation, the evolution of the ionizing background can be derived self-consistently given a model for the small absorbers. The hydrogen ionization rate of the ionizing background is reduced by an order of magnitude in the presence of dense absorbers.

New insights about enzyme evolution from large scale studies of sequence and structure relationships.

Science.gov (United States)

Brown, Shoshana D; Babbitt, Patricia C

2014-10-31

Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfamilies, each representing a large set of sequences that evolved from a common ancestor and that retain conserved features of their structures and active sites. Using several examples, we describe the different structural strategies nature has used to evolve new reaction and substrate specificities in each unique superfamily. The results provide insight about enzyme evolution that is not easily obtained from studies of one or only a few enzymes. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

The Mars water cycle at other epochs: History of the polar caps and layered terrain

Science.gov (United States)

Jakosky, Bruce M.; Henderson, Bradley G.; Mellon, Michael T.

1992-01-01

The atmospheric water cycle at the present epoch involves summertime sublimation of water from the north polar cap, transport of water through the atmosphere, and condensation on one or both winter CO2 caps. Exchange with the regolith is important seasonally, but the water content of the atmosphere appears to be controlled by the polar caps. The net annual transport through the atmosphere, integrated over long timescales, must be the driving force behind the long-term evolution of the polar caps; clearly, this feeds back into the evolution of the layered terrain. We have investigated the behavior of the seasonal water cycle and the net integrated behavior at the pole for the last 10 exp 7 years. Our model of the water cycle includes the solar input, CO2 condensation and sublimation, and summertime water sublimation through the seasonal cycles, and incorporates the long-term variations in the orbital elements describing the Martian orbit.

Astrobiology, Evolution, and Society: Public Engagement Insights

Science.gov (United States)

Bertka, C. M.

2009-12-01

frequently was “my religious beliefs.” A review of religious identification in this country will be presented in the context of offering insights for public engagement on the topic of evolution, and the contribution that astrobiology could make to encouraging a positive relationship between science and religion. A widespread acceptance of evolution in the United States may require that the scientific community go beyond a simple contrast approach to science and religion and be willing to encourage, and participate in, a program of in-depth and long-term engagement with theologians and religious community leaders. Astrobiology as a discipline is particularly burdened, perhaps blessed, with the responsibility to engage this issue. After all, humanity itself may be inherently defined by the ability we collectively posses to ask “Where did we come from?,” “Are we alone?,” and “Where are we going?”

Pulsar slow-down epochs

International Nuclear Information System (INIS)

Heintzmann, H.; Novello, M.

1981-01-01

The relative importance of magnetospheric currents and low frequency waves for pulsar braking is assessed and a model is developed which tries to account for the available pulsar timing data under the unifying aspect that all pulsars have equal masses and magnetic moments and are born as rapid rotators. Four epochs of slow-down are distinguished which are dominated by different braking mechanisms. According to the model no direct relationship exists between 'slow-down age' and true age of a pulsar and leads to a pulsar birth-rate of one event per hundred years. (Author) [pt

Phylogenomic Insights into Animal Evolution.

Science.gov (United States)

Telford, Maximilian J; Budd, Graham E; Philippe, Hervé

2015-10-05

Animals make up only a small fraction of the eukaryotic tree of life, yet, from our vantage point as members of the animal kingdom, the evolution of the bewildering diversity of animal forms is endlessly fascinating. In the century following the publication of Darwin's Origin of Species, hypotheses regarding the evolution of the major branches of the animal kingdom - their relationships to each other and the evolution of their body plans - was based on a consideration of the morphological and developmental characteristics of the different animal groups. This morphology-based approach had many successes but important aspects of the evolutionary tree remained disputed. In the past three decades, molecular data, most obviously primary sequences of DNA and proteins, have provided an estimate of animal phylogeny largely independent of the morphological evolution we would ultimately like to understand. The molecular tree that has evolved over the past three decades has drastically altered our view of animal phylogeny and many aspects of the tree are no longer contentious. The focus of molecular studies on relationships between animal groups means, however, that the discipline has become somewhat divorced from the underlying biology and from the morphological characteristics whose evolution we aim to understand. Here, we consider what we currently know of animal phylogeny; what aspects we are still uncertain about and what our improved understanding of animal phylogeny can tell us about the evolution of the great diversity of animal life. Copyright © 2015 Elsevier Ltd. All rights reserved.

Brain network segregation and integration during an epoch-related working memory fMRI experiment.

Science.gov (United States)

Fransson, Peter; Schiffler, Björn C; Thompson, William Hedley

2018-05-17

The characterization of brain subnetwork segregation and integration has previously focused on changes that are detectable at the level of entire sessions or epochs of imaging data. In this study, we applied time-varying functional connectivity analysis together with temporal network theory to calculate point-by-point estimates in subnetwork segregation and integration during an epoch-based (2-back, 0-back, baseline) working memory fMRI experiment as well as during resting-state. This approach allowed us to follow task-related changes in subnetwork segregation and integration at a high temporal resolution. At a global level, the cognitively more taxing 2-back epochs elicited an overall stronger response of integration between subnetworks compared to the 0-back epochs. Moreover, the visual, sensorimotor and fronto-parietal subnetworks displayed characteristic and distinct temporal profiles of segregation and integration during the 0- and 2-back epochs. During the interspersed epochs of baseline, several subnetworks, including the visual, fronto-parietal, cingulo-opercular and dorsal attention subnetworks showed pronounced increases in segregation. Using a drift diffusion model we show that the response time for the 2-back trials are correlated with integration for the fronto-parietal subnetwork and correlated with segregation for the visual subnetwork. Our results elucidate the fast-evolving events with regard to subnetwork integration and segregation that occur in an epoch-related task fMRI experiment. Our findings suggest that minute changes in subnetwork integration are of importance for task performance. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Epoch-based Entropy for Early Screening of Alzheimer's Disease.

Science.gov (United States)

Houmani, N; Dreyfus, G; Vialatte, F B

2015-12-01

In this paper, we introduce a novel entropy measure, termed epoch-based entropy. This measure quantifies disorder of EEG signals both at the time level and spatial level, using local density estimation by a Hidden Markov Model on inter-channel stationary epochs. The investigation is led on a multi-centric EEG database recorded from patients at an early stage of Alzheimer's disease (AD) and age-matched healthy subjects. We investigate the classification performances of this method, its robustness to noise, and its sensitivity to sampling frequency and to variations of hyperparameters. The measure is compared to two alternative complexity measures, Shannon's entropy and correlation dimension. The classification accuracies for the discrimination of AD patients from healthy subjects were estimated using a linear classifier designed on a development dataset, and subsequently tested on an independent test set. Epoch-based entropy reached a classification accuracy of 83% on the test dataset (specificity = 83.3%, sensitivity = 82.3%), outperforming the two other complexity measures. Furthermore, it was shown to be more stable to hyperparameter variations, and less sensitive to noise and sampling frequency disturbances than the other two complexity measures.

A six-gene phylogeny provides new insights into choanoflagellate evolution.

Science.gov (United States)

Carr, Martin; Richter, Daniel J; Fozouni, Parinaz; Smith, Timothy J; Jeuck, Alexandra; Leadbeater, Barry S C; Nitsche, Frank

2017-02-01

Recent studies have shown that molecular phylogenies of the choanoflagellates (Class Choanoflagellatea) are in disagreement with their traditional taxonomy, based on morphology, and that Choanoflagellatea requires considerable taxonomic revision. Furthermore, phylogenies suggest that the morphological and ecological evolution of the group is more complex than has previously been recognized. Here we address the taxonomy of the major choanoflagellate order Craspedida, by erecting four new genera. The new genera are shown to be morphologically, ecologically and phylogenetically distinct from other choanoflagellate taxa. Furthermore, we name five novel craspedid species, as well as formally describe ten species that have been shown to be either misidentified or require taxonomic revision. Our revised phylogeny, including 18 new species and sequence data for two additional genes, provides insights into the morphological and ecological evolution of the choanoflagellates. We examine the distribution within choanoflagellates of these two additional genes, EF-1A and EFL, closely related translation GTPases which are required for protein synthesis. Mapping the presence and absence of these genes onto the phylogeny highlights multiple events of gene loss within the choanoflagellates. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

SPECTROPOLARIMETRY OF SUPERLUMINOUS SUPERNOVAE: INSIGHT INTO THEIR GEOMETRY

Energy Technology Data Exchange (ETDEWEB)

Inserra, C.; Bulla, M.; Sim, S. A.; Smartt, S. J., E-mail: c.inserra@qub.ac.uk [Astrophysics Research Centre, School of Mathematics and Physics, Queens University Belfast, Belfast BT7 1NN (United Kingdom)

2016-11-01

We present the first spectropolarimetric observations of a hydrogen-free superluminous supernova (SLSN) at z = 0.1136, namely SN 2015bn. The transient shows significant polarization at both of the observed epochs: one 24 days before maximum light in the rest-frame, and the other at 27 days after peak luminosity. Analysis of the Q – U plane suggests the presence of a dominant axis and no physical departure from the main axis at either epoch. The polarization spectrum along the dominant axis is characterized by a strong wavelength dependence and an increase in the signal from the first to the second epoch. We use a Monte Carlo code to demonstrate that these properties are consistent with a simple toy model that adopts an axisymmetric ellipsoidal configuration for the ejecta. We find that the wavelength dependence of the polarization is possibly due to a strong wavelength dependence in the line opacity, while the higher level of polarization at the second epoch is a consequence of the increase in the asphericity of the inner layers of the ejecta or the fact that the photosphere recedes into less spherical layers. The geometry of the SLSN is similar to that of stripped-envelope core-collapse SNe connected to GRB, while the overall evolution of the ejecta shape could be consistent with a central engine.

LEDDB : LOFAR Epoch of Reionization Diagnostic Database

NARCIS (Netherlands)

Martinez-Rubi, O.; Veligatla, V. K.; de Bruyn, A. G.; Lampropoulos, P.; Offringa, A. R.; Jelic, V.; Yatawatta, S.; Koopmans, L. V. E.; Zaroubi, S.

2013-01-01

One of the key science projects of the Low-Frequency Array (LOFAR) is the detection of the cosmological signal coming from the Epoch of Reionization (EoR). Here we present the LOFAR EoR Diagnostic Database (LEDDB) that is used in the storage, management, processing and analysis of the LOFAR EoR

A superposed epoch analysis of geomagnetic storms

Directory of Open Access Journals (Sweden)

J. R. Taylor

1994-06-01

Full Text Available A superposed epoch analysis of geomagnetic storms has been undertaken. The storms are categorised via their intensity (as defined by the Dst index. Storms have also been classified here as either storm sudden commencements (SSCs or storm gradual commencements (SGCs, that is all storms which did not begin with a sudden commencement. The prevailing solar wind conditions defined by the parameters solar wind speed (vsw, density (ρsw and pressure (Psw and the total field and the components of the interplanetary magnetic field (IMF during the storms in each category have been investigated by a superposed epoch analysis. The southward component of the IMF, appears to be the controlling parameter for the generation of small SGCs (-100 nT< minimum Dst ≤ -50 nT for ≥ 4 h, but for SSCs of the same intensity solar wind pressure is dominant. However, for large SSCs (minimum Dst ≤ -100 nT for ≥ 4 h the solar wind speed is the controlling parameter. It is also demonstrated that for larger storms magnetic activity is not solely driven by the accumulation of substorm activity, but substantial energy is directly input via the dayside. Furthermore, there is evidence that SSCs are caused by the passage of a coronal mass ejection, whereas SGCs result from the passage of a high speed/ slow speed coronal stream interface. Storms are also grouped by the sign of Bz during the first hour epoch after the onset. The sign of Bz at t = +1 h is the dominant sign of the Bz for ~24 h before the onset. The total energy released during storms for which Bz was initially positive is, however, of the same order as for storms where Bz was initially negative.

The Importance of Lake Overflow Floods for Early Martian Landscape Evolution: Insights From Licus Vallis

Science.gov (United States)

Goudge, T. A.; Fassett, C. I.

2017-01-01

Open-basin lake outlet valleys are incised when water breaches the basin-confining topography and overflows. Outlet valleys record this flooding event and provide insight into how the lake and surrounding terrain evolved over time. Here we present a study of the paleolake outlet Licus Vallis, a >350 km long, >2 km wide, >100 m deep valley that heads at the outlet breach of an approx.30 km diameter impact crater. Multiple geomorphic features of this valley system suggest it records a more complex evolution than formation from a single lake overflow flood. This provides unique insight into the paleohydrology of lakes on early Mars, as we can make inferences beyond the most recent phase of activity..

Assessing worst case scenarios in movement demands derived from global positioning systems during international rugby union matches: Rolling averages versus fixed length epochs

Science.gov (United States)

Cunningham, Daniel J.; Shearer, David A.; Carter, Neil; Drawer, Scott; Pollard, Ben; Bennett, Mark; Eager, Robin; Cook, Christian J.; Farrell, John; Russell, Mark

2018-01-01

The assessment of competitive movement demands in team sports has traditionally relied upon global positioning system (GPS) analyses presented as fixed-time epochs (e.g., 5–40 min). More recently, presenting game data as a rolling average has become prevalent due to concerns over a loss of sampling resolution associated with the windowing of data over fixed periods. Accordingly, this study compared rolling average (ROLL) and fixed-time (FIXED) epochs for quantifying the peak movement demands of international rugby union match-play as a function of playing position. Elite players from three different squads (n = 119) were monitored using 10 Hz GPS during 36 matches played in the 2014–2017 seasons. Players categorised broadly as forwards and backs, and then by positional sub-group (FR: front row, SR: second row, BR: back row, HB: half back, MF: midfield, B3: back three) were monitored during match-play for peak values of high-speed running (>5 m·s-1; HSR) and relative distance covered (m·min-1) over 60–300 s using two types of sample-epoch (ROLL, FIXED). Irrespective of the method used, as the epoch length increased, values for the intensity of running actions decreased (e.g., For the backs using the ROLL method, distance covered decreased from 177.4 ± 20.6 m·min-1 in the 60 s epoch to 107.5 ± 13.3 m·min-1 for the 300 s epoch). For the team as a whole, and irrespective of position, estimates of fixed effects indicated significant between-method differences across all time-points for both relative distance covered and HSR. Movement demands were underestimated consistently by FIXED versus ROLL with differences being most pronounced using 60 s epochs (95% CI HSR: -6.05 to -4.70 m·min-1, 95% CI distance: -18.45 to -16.43 m·min-1). For all HSR time epochs except one, all backs groups increased more (p < 0.01) from FIXED to ROLL than the forward groups. Linear mixed modelling of ROLL data highlighted that for HSR (except 60 s epoch), SR was the only group not

The Formation and Evolution of Tessera and Insights into the Beginning of Recorded History on Venus: Geology of the Fortuna Tessera Quadrangle (V-2)

Science.gov (United States)

Head, J. W.; Ivanov, M. A.

2010-01-01

Today, and throughout its recorded history, Venus can be classified as a "one-plate planet." The observable geological record of the planet comprises only the last 1/4 or less of its overall geologic history. As shown by many authors, it started with intensive deformation in broad regions to form tessera [1-6] during the Fortunian period of history [7]. The period of tessera formation quickly changed to numerous zonal deformational belts of ridges and grooves that were followed by emplacement of vast volcanic plains (shield plains, regional plains) [7,8]. During the final epoch of the geologic history of Venus, large but isolated centers of volcanism formed extensive fields of lavas, with tectonics concentrated within fewer very prominent rift zones [8,9]. The observable changes in intensity and character of volcanism and tectonics suggest progressive changes from thin lithosphere early in the geologic history to thick lithosphere during later epochs [6,10]. We have little idea of the character of the first 3/4 of Venus' history. So, what does the earliest period of recorded history tell us about the transition from the Pre-Fortunian to the Fortunian period and what insight does this give us into this earlier period?

Cluster evolution

International Nuclear Information System (INIS)

Schaeffer, R.

1987-01-01

The galaxy and cluster luminosity functions are constructed from a model of the mass distribution based on hierarchical clustering at an epoch where the matter distribution is non-linear. These luminosity functions are seen to reproduce the present distribution of objects as can be inferred from the observations. They can be used to deduce the redshift dependence of the cluster distribution and to extrapolate the observations towards the past. The predicted evolution of the cluster distribution is quite strong, although somewhat less rapid than predicted by the linear theory

Improving the repeatability of Motor Unit Number Index (MUNIX) by introducing additional epochs at low contraction levels.

Science.gov (United States)

Peng, Yun; Zhang, Yingchun

2017-07-01

To evaluate the repeatability of (Motor Unit Number Index) MUNIX under repeatability conditions, specify the origin of variations and provide strategies for quality control. MUNIX calculations were performed on the bicep brachii muscles of eight healthy subjects. Negative effect of suboptimal electrode positions on MUNIX accuracy was eliminated by employing the high-density surface electromyography technique. MUNIX procedures that utilized a variety of surface interferential pattern (SIP) epoch recruitment strategies (including the original MUNIX procedure, two proposed improvement strategies and their combinations) were described. For each MUNIX procedure, ten thousands of different SIP pools were constructed by randomly recruiting necessary SIP epochs from a large SIP epoch pool (3 datasets, 9 independent electromyography recordings at different contraction levels per dataset and 10 SIP epochs per recording) and implemented for MUNIX calculation. The repeatability of each MUNIX procedure was assessed by summarizing the resulting MUNIX distribution and compared to investigate the effect of SIP epoch selection strategy on repeatability performance. SIP epochs selected at lower contraction levels have a stronger influence on the repeatability of MUNIX than those selected at higher contraction levels. MUNIX under repeatability conditions follows a normal distribution and the standard deviation can be significantly reduced by introducing more epochs near the MUNIX definition line. The MUNIX technique shows an inherent variation attributable to SIP epochs at low contraction levels. It is recommended that more epochs should be sampled at these low contraction levels to improve the repeatability. The present study thoroughly documented the inherent variation of MUNIX and the causes, and offered practical solutions to improve the repeatability of MUNIX. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

Y-chromosome evolution: emerging insights into processes of Y-chromosome degeneration.

Science.gov (United States)

Bachtrog, Doris

2013-02-01

The human Y chromosome is intriguing not only because it harbours the master-switch gene that determines gender but also because of its unusual evolutionary history. The Y chromosome evolved from an autosome, and its evolution has been characterized by massive gene decay. Recent whole-genome and transcriptome analyses of Y chromosomes in humans and other primates, in Drosophila species and in plants have shed light on the current gene content of the Y chromosome, its origins and its long-term fate. Furthermore, comparative analysis of young and old Y chromosomes has given further insights into the evolutionary and molecular forces triggering Y-chromosome degeneration and into the evolutionary destiny of the Y chromosome.

Self-shielding of hydrogen in the IGM during the epoch of reionization

Science.gov (United States)

Chardin, Jonathan; Kulkarni, Girish; Haehnelt, Martin G.

2018-04-01

We investigate self-shielding of intergalactic hydrogen against ionizing radiation in radiative transfer simulations of cosmic reionization carefully calibrated with Lyα forest data. While self-shielded regions manifest as Lyman-limit systems in the post-reionization Universe, here we focus on their evolution during reionization (redshifts z = 6-10). At these redshifts, the spatial distribution of hydrogen-ionizing radiation is highly inhomogeneous, and some regions of the Universe are still neutral. After masking the neutral regions and ionizing sources in the simulation, we find that the hydrogen photoionization rate depends on the local hydrogen density in a manner very similar to that in the post-reionization Universe. The characteristic physical hydrogen density above which self-shielding becomes important at these redshifts is about nH ˜ 3 × 10-3 cm-3, or ˜20 times the mean hydrogen density, reflecting the fact that during reionization photoionization rates are typically low enough that the filaments in the cosmic web are often self-shielded. The value of the typical self-shielding density decreases by a factor of 3 between redshifts z = 3 and 10, and follows the evolution of the average photoionization rate in ionized regions in a simple fashion. We provide a simple parameterization of the photoionization rate as a function of density in self-shielded regions during the epoch of reionization.

Hydrogen Epoch of Reionization Array (HERA)

Science.gov (United States)

DeBoer, David R.; HERA

2015-01-01

The Hydrogen Epoch of Reionization Arrays (HERA - reionization.org) roadmap uses the unique properties of the neutral hydrogen (HI) 21cm line to probe our cosmic dawn: from the birth of the first stars and black holes, through the full reionization of the primordial intergalactic medium (IGM). HERA is a collaboration between the Precision Array Probing the Epoch of Reionization (PAPER - eor.berkeley.edu), the US-based Murchison Widefield Array (MWA - mwatelescope.org), and MIT Epoch of Reionization (MITEOR) teams along with the South African SKA-SA, University of KwaZulu Natal and the University of Cambridge Cavendish Laborabory. HERA has recently been awarded a National Science Foundation Mid-Scale Innovation Program grant to begin the next phase.HERA leverages the operation of the PAPER and MWA telescopes to explore techniques and designs required to detect the primordial HI signal in the presence of systematics and radio continuum foreground emission some four orders of magnitude brighter. With this understanding, we are now able to remove foregrounds to the limits of our sensitivity, culminating in the first physically meaningful upper limits. A redundant calibration algorithm from MITEOR improves the sensitivity of the approach.Building on this, the next stage of HERA incorporates a 14m diameter antenna element that is optimized both for sensitivity and for minimizing foreground systematics. Arranging these elements in a compact hexagonal grid yields an array that facilitates calibration, leverages proven foreground removal techniques, and is scalable to large collecting areas. HERA will be located in the radio quiet environment of the SKA site in the Karoo region of South Africa (where PAPER is currently located). It will have a sensitivity close to two orders of magnitude better than PAPER and the MWA to ensure a robust detection. With its sensitivity and broader frequency coverage, HERA can paint an uninterrupted picture through reionization, back to the

The Galaxy mass function up to z =4 in the GOODS-MUSIC sample: into the epoch of formation of massive galaxies

Science.gov (United States)

Fontana, A.; Salimbeni, S.; Grazian, A.; Giallongo, E.; Pentericci, L.; Nonino, M.; Fontanot, F.; Menci, N.; Monaco, P.; Cristiani, S.; Vanzella, E.; de Santis, C.; Gallozzi, S.

2006-12-01

Aims.The goal of this work is to measure the evolution of the Galaxy Stellar Mass Function and of the resulting Stellar Mass Density up to redshift ≃4, in order to study the assembly of massive galaxies in the high redshift Universe. Methods: .We have used the GOODS-MUSIC catalog, containing 3000 Ks-selected galaxies with multi-wavelength coverage extending from the U band to the Spitzer 8 μm band, of which 27% have spectroscopic redshifts and the remaining fraction have accurate photometric redshifts. On this sample we have applied a standard fitting procedure to measure stellar masses. We compute the Galaxy Stellar Mass Function and the resulting Stellar Mass Density up to redshift ≃4, taking into proper account the biases and incompleteness effects. Results: .Within the well known trend of global decline of the Stellar Mass Density with redshift, we show that the decline of the more massive galaxies may be described by an exponential timescale of ≃6 Gyr up to z≃ 1.5, and proceeds much faster thereafter, with an exponential timescale of ≃0.6 Gyr. We also show that there is some evidence for a differential evolution of the Galaxy Stellar Mass Function, with low mass galaxies evolving faster than more massive ones up to z≃ 1{-}1.5 and that the Galaxy Stellar Mass Function remains remarkably flat (i.e. with a slope close to the local one) up to z≃ 1{-}1.3. Conclusions: .The observed behaviour of the Galaxy Stellar Mass Function is consistent with a scenario where about 50% of present-day massive galaxies formed at a vigorous rate in the epoch between redshift 4 and 1.5, followed by a milder evolution until the present-day epoch.

The effect of epoch length on estimated EEG functional connectivity and brain network organisation

Science.gov (United States)

Fraschini, Matteo; Demuru, Matteo; Crobe, Alessandra; Marrosu, Francesco; Stam, Cornelis J.; Hillebrand, Arjan

2016-06-01

Objective. Graph theory and network science tools have revealed fundamental mechanisms of functional brain organization in resting-state M/EEG analysis. Nevertheless, it is still not clearly understood how several methodological aspects may bias the topology of the reconstructed functional networks. In this context, the literature shows inconsistency in the chosen length of the selected epochs, impeding a meaningful comparison between results from different studies. Approach. The aim of this study was to provide a network approach insensitive to the effects that epoch length has on functional connectivity and network reconstruction. Two different measures, the phase lag index (PLI) and the amplitude envelope correlation (AEC) were applied to EEG resting-state recordings for a group of 18 healthy volunteers using non-overlapping epochs with variable length (1, 2, 4, 6, 8, 10, 12, 14 and 16 s). Weighted clustering coefficient (CCw), weighted characteristic path length (L w) and minimum spanning tree (MST) parameters were computed to evaluate the network topology. The analysis was performed on both scalp and source-space data. Main results. Results from scalp analysis show a decrease in both mean PLI and AEC values with an increase in epoch length, with a tendency to stabilize at a length of 12 s for PLI and 6 s for AEC. Moreover, CCw and L w show very similar behaviour, with metrics based on AEC more reliable in terms of stability. In general, MST parameters stabilize at short epoch lengths, particularly for MSTs based on PLI (1-6 s versus 4-8 s for AEC). At the source-level the results were even more reliable, with stability already at 1 s duration for PLI-based MSTs. Significance. The present work suggests that both PLI and AEC depend on epoch length and that this has an impact on the reconstructed network topology, particularly at the scalp-level. Source-level MST topology is less sensitive to differences in epoch length, therefore enabling the comparison of brain

Geomagnetic reversal in brunhes normal polarity epoch.

Science.gov (United States)

Smith, J D; Foster, J H

1969-02-07

The magnetic stratigraphly of seven cores of deep-sea sediment established the existence of a short interval of reversed polarity in the upper part of the Brunches epoch of normal polarity. The reversed zone in the cores correlates well with paleontological boundaries and is named the Blake event. Its boundaries are estimated to be 108,000 and 114,000 years ago +/- 10 percent.

Primordial black hole formation during the QCD epoch

International Nuclear Information System (INIS)

Jedamzik, K.

1997-01-01

We consider the formation of horizon-size primordial black holes (PBH close-quote s) from pre-existing density fluctuations during cosmic phase transitions. It is pointed out that the formation of PBH close-quote s should be particularly efficient during the QCD epoch due to a substantial reduction of pressure forces during adiabatic collapse, or equivalently, a significant decrease in the effective speed of sound during the color-confinement transition. Our considerations imply that for generic initial density perturbation spectra PBH mass functions are expected to exhibit a pronounced peak on the QCD-horizon mass scale ∼1M circle-dot . This mass scale is roughly coincident with the estimated masses for compact objects recently observed in our galactic halo by the MACHO Collaboration. Black holes formed during the QCD epoch may offer an attractive explanation for the origin of halo dark matter evading possibly problematic nucleosynthesis and luminosity bounds on baryonic halo dark matter. copyright 1997 The American Physical Society

On the evolution of the primordial cosmic turbulence

International Nuclear Information System (INIS)

Tanabe, Kenji.

1980-09-01

The evolution of the primordial cosmic turbulence in the big-bang universe is studied by numerical integration of the spectral equation derived by Nariai and closed by Heisenberg's hypothesis. In order to examine whether the turbulence can survive by the epoch of the plasma recombination, the equation is dealt with by taking full account of the viscosity effect. The main conclusion is that the resulting spectrum survived against the viscous decay depends on the initial spectral shape which is assumed at the epoch t sub(eq) when the density of matter is equal to that of radiation. The Taylor's micro-scale is also calculated which is available to determine the fate of the primordial cosmic turbulence. (author)

The Reel Deal: Interpreting HST Multi-Epoch Movies of YSO Jets.

Science.gov (United States)

Frank, Adam

2010-09-01

The goal of this proposal is to bring the theoretical interpretation of Young Stellar Object jets and their environments to a new level of realism. We propose to build on the results of a successful Cycle 16 observing proposal that has obtained 3rd epoch images of HH jets. We will use Adaptive Mesh Refinement MHD simulations {developed by our team} to carry forward a detailed program of modeling and interpretation of the time-dependent behavior revealed in the new, extended multi-epoch data set. Only with the third epoch observations can we explore forces: i.e. accelerations, decelerations and structural changes to develop an accurate understanding of physical processes occurring in hypersonic, magnetized jet flows. Our studies will allow us to characterize the jets and, therefore, make the crucial link with jet central engines. We note an innovative feature of our project is its link with laboratory astrophysical experiments of jets. Our analysis of the observations will be used to determine future laboratory experiments which will explore A?clumpyA? jet propagation issues.

Clinical and Cost Comparison Evaluation of Inpatient Versus Outpatient Administration of EPOCH-Containing Regimens in Non-Hodgkin Lymphoma.

Science.gov (United States)

Evans, Sarah S; Gandhi, Arpita S; Clemmons, Amber B; DeRemer, David L

2017-08-01

Etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin (EPOCH)-containing regimens are frequently utilized in non-Hodgkin's lymphoma, however, the incidence of febrile neutropenia (FN) in patients receiving inpatient versus outpatient EPOCH has not been described. Additionally, no comparisons have been made regarding financial implications of EPOCH administration in either setting. This study's primary objective was to compare hospital admissions for FN in patients receiving inpatient or outpatient EPOCH. A single-center, institutional review board-approved review was conducted for adults receiving EPOCH beginning January 2010. Clinical and financial data were collected through chart review and the institution's financial department. Descriptive statistics were utilized for analysis. A total of 25 patients received 86 cycles of an EPOCH-containing regimen (61 [70.9%] inpatient). Five (8.2%) inpatient cycles resulted in an admission for FN compared to 4 (16%) outpatient cycles. Prophylactic antifungal and antiviral agents were prescribed more often after inpatient cycles (>80%) compared to outpatient cycles (cost savings of approximately US$141 116 for both chemotherapy costs and hospital day avoidance. EPOCH-containing regimens can be safely administered in the outpatient setting, which may result in cost savings for healthcare institutions.

A search for changing look quasars in second epoch imaging

Science.gov (United States)

Findlay, Joseph; Myers, Adam; McGreer, Ian

2018-01-01

Over nearly two decades, the Sloan Digital Sky Survey has compiled a catalog of over half a million confirmed quasars. During that period approximately ten percent of these objects have been spectroscopically observed in two or more epochs over baselines of ten or more years. This led recently to the discovery of the largest change in luminosity ever before observed in a quasar. The dimming emission was a reflection of very significant changes in continuum and broad line properties, the source had effectively transitioned from a Type I quasar to a Type II AGN. Since then several more "changing look" quasars have been discovered in multi-epoch SDSS spectroscopy. Among them are objects with rising and falling luminosities, appearing and disappearing broad lines. The origin of this behavior is still very uncertain, currently favored is the scenario in which an accreting black hole is simply starved of fuel. Other plausible scenarios include flaring due to stellar tidal disruption close to the black hole or large changes in accretion flow, which can occur during transitions between radiatively efficient and inefficient accretion regimes. Monitoring of larger numbers of changing look quasars will help to elucidate these ideas.In this poster, we report on the progress of a pilot study in which we hope to learn how to select changing look quasars in multi-epoch imaging. This will allow us to take advantage of the entire SDSS quasar catalog rather than just the ten percent of objects with multi-epoch spectroscopy. Comparing archival SDSS and more recent Legacy Survey imaging over ten-year baselines we select objects whose photometry is consistent with the large changes in luminosity expected in changing look quasars. We aim to build up a catalog of both transitioned and transitioning objects for future monitoring.

Comparative genomics provide insights into evolution of trichoderma nutrition style.

Science.gov (United States)

Xie, Bin-Bin; Qin, Qi-Long; Shi, Mei; Chen, Lei-Lei; Shu, Yan-Li; Luo, Yan; Wang, Xiao-Wei; Rong, Jin-Cheng; Gong, Zhi-Ting; Li, Dan; Sun, Cai-Yun; Liu, Gui-Ming; Dong, Xiao-Wei; Pang, Xiu-Hua; Huang, Feng; Liu, Weifeng; Chen, Xiu-Lan; Zhou, Bai-Cheng; Zhang, Yu-Zhong; Song, Xiao-Yan

2014-02-01

Saprotrophy on plant biomass is a recently developed nutrition strategy for Trichoderma. However, the physiology and evolution of this new nutrition strategy is still elusive. We report the deep sequencing and analysis of the genome of Trichoderma longibrachiatum, an efficient cellulase producer. The 31.7-Mb genome, smallest among the sequenced Trichoderma species, encodes fewer nutrition-related genes than saprotrophic T. reesei (Tr), including glycoside hydrolases and nonribosomal peptide synthetase-polyketide synthase. Homology and phylogenetic analyses suggest that a large number of nutrition-related genes, including GH18 chitinases, β-1,3/1,6-glucanases, cellulolytic enzymes, and hemicellulolytic enzymes, were lost in the common ancestor of T. longibrachiatum (Tl) and Tr. dN/dS (ω) calculation indicates that all the nutrition-related genes analyzed are under purifying selection. Cellulolytic enzymes, the key enzymes for saprotrophy on plant biomass, are under stronger purifying selection pressure in Tl and Tr than in mycoparasitic species, suggesting that development of the nutrition strategy of saprotrophy on plant biomass has increased the selection pressure. In addition, aspartic proteases, serine proteases, and metalloproteases are subject to stronger purifying selection pressure in Tl and Tr, suggesting that these enzymes may also play important roles in the nutrition. This study provides insights into the physiology and evolution of the nutrition strategy of Trichoderma.

'Anthropocene': An Ethical Crisis, Not a Geological Epoch

Science.gov (United States)

Cuomo, Chris

2017-04-01

The term 'anthropocene' has gained enormous popularity among scientists who believe we are in a global phase distinguished by the extensive and lasting impacts of social activities on Earth's sedimentary record and vital systems. Beyond its widespread informal use, a working group of the International Union of Geological Sciences seeks to formalize the term to name a new geological epoch, implying that the Holocene epoch has ended. I argue that the move to formalize the 'anthropocene' and to declare the demise of the Holocene is premature and ethically misguided, at best, and that the very name 'anthropocene' obscures rather than illuminates the serious moral and political/economic implications of the dire warnings evident in recent stratigraphic and ecological changes. If human-caused mass extinction and other ecological catastrophes are serious harms, ethical responses are required. Instead, the move to formalize the idea of an 'anthropocene' epoch treats dire ethical warnings as an opportunity to redefine the current dangerous situation as a new status quo. Have we met our responsibilities to protect Holocene Earth? This presentation will focus on the ethical implications of using the power and discourse of geology to demote Holocene ecological states from their role as the foundational benchmarks for guiding and assessing human relationships with nature and other species. Have geoscientists adequately consulted the biological, ecological and social sciences before declaring the end of the Holocene epoch? Upon what do we base environmental ethics if the Holocene is considered past history? I will also examine the ethical dimensions of naming the so-called 'anthropocene', asking: who is the presumed 'anthro' in the 'anthropocene'? Are the phenomena identified with the 'anthropocene' (nuclear fallout, mass species endangerment, ocean acidification, fossil fuel pollution, deforestation, mining) definitive accomplishments of the human species? Should the practices

Evolution of the Cosmic Web

Science.gov (United States)

Einasto, J.

2017-07-01

In the evolution of the cosmic web dark energy plays an important role. To understand the role of dark energy we investigate the evolution of superclusters in four cosmological models: standard model SCDM, conventional model LCDM, open model OCDM, and a hyper-dark-energy model HCDM. Numerical simulations of the evolution are performed in a box of size 1024 Mpc/h. Model superclusters are compared with superclusters found for Sloan Digital Sky Survey (SDSS). Superclusters are searched using density fields. LCDM superclusters have properties, very close to properties of observed SDSS superclusters. Standard model SCDM has about 2 times more superclusters than other models, but SCDM superclusters are smaller and have lower luminosities. Superclusters as principal structural elements of the cosmic web are present at all cosmological epochs.

Evolution, Insight and Truth?

Science.gov (United States)

Newall, Emma

2017-01-01

Evolution has been positioned at the centre of conflict between scientific and religious explanations of the workings of the world. However, little research has examined other possible reasons for some people rejecting scientific explanations. The author's research indicates that for some people, irrespective of faith, the ideas associated with…

Constraining the Evolution of the Ionizing Background and the Epoch of Reionization with z~6 Quasars. II. A Sample of 19 Quasars

Science.gov (United States)

Fan, Xiaohui; Strauss, Michael A.; Becker, Robert H.; White, Richard L.; Gunn, James E.; Knapp, Gillian R.; Richards, Gordon T.; Schneider, Donald P.; Brinkmann, J.; Fukugita, Masataka

2006-07-01

We study the evolution of the ionization state of the intergalactic medium (IGM) at the end of the reionization epoch using moderate-resolution spectra of a sample of 19 quasars at 5.745.7: the GP optical depth evolution changes from τeffGP~(1+z)4.3 to (1+z)>~11, and the average length of dark gaps with τ>3.5 increases from 80 comoving Mpc. The dispersion of IGM properties along different lines of sight also increases rapidly, implying fluctuations by a factor of >~4 in the UV background at z>6, when the mean free path of UV photons is comparable to the correlation length of the star-forming galaxies that are thought to have caused reionization. The mean length of dark gaps shows the most dramatic increase at z~6, as well as the largest line-of-sight variations. We suggest using dark gap statistics as a powerful probe of the ionization state of the IGM at yet higher redshift. The sizes of H II regions around luminous quasars decrease rapidly toward higher redshift, suggesting that the neutral fraction of the IGM has increased by a factor of >~10 from z=5.7 to 6.4, consistent with the value derived from the GP optical depth. The mass-averaged neutral fraction is 1%-4% at z~6.2 based on the GP optical depth and H II region size measurements. The observations suggest that z~6 is the end of the overlapping stage of reionization and are inconsistent with a mostly neutral IGM at z~6, as indicated by the finite length of the dark absorption gaps. Based on observations obtained with the Sloan Digital Sky Survey at the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration, made possible by the generous financial support of the W. M. Keck Foundation, with the MMT Observatory, a joint facility of the University of Arizona and the Smithsonian Institution, and with the Kitt Peak National Observatory 4 m Mayall Telescope. This paper

The evolution of Yellowstone's magmatic system over the past 630 kyr: Insights from the crystal record

Science.gov (United States)

Stelten, M. E.

2017-12-01

The Yellowstone Plateau volcanic field in northwestern Wyoming is one of the world's largest, active silicic volcanic centers, and has produced three caldera-forming "super eruptions" over the past 2.1 Myr. As a result, the petrologic evolution of Yellowstone's magmatic system has been the focus of numerous studies over the past 60 years. Early studies at Yellowstone focused on characterizing whole-rock chemical and isotopic variations observed in magmas erupted over Yellowstone's lifetime. While these have provided important insights into the source of Yellowstone magmas and the processes controlling their compositional evolution though time, whole-rock studies are limited in their ability to identify the mechanisms and timescales of rhyolite generation. In contrast, much of the recent work at Yellowstone has focused on applying micro-analytical techniques to characterize the age and composition of phenocrysts hosted in Yellowstone rhyolites. These studies have greatly advanced our understanding of the magmatic system at Yellowstone and have provided crucial new insights into the mechanisms and timescales of rhyolite generation. In particular, recent work has focused on applying micro-analytical techniques to study the age and origin of the [1] three caldera-forming eruptions that produced the Huckleberry Ridge, Mesa Falls, Lava Creek tuffs and [2] post-Lava Creek tuff intracaldera rhyolites that compose the Plateau Rhyolite. As a result, a wealth of crystal-chemical data now exists for rhyolites erupted throughout Yellowstone's 2.1 Myr history. These data provide a unique opportunity to create a detailed reconstruction of Yellowstone's magmatic system through time. In this contribution, I integrate available age, chemical, and isotopic data for phenocrysts hosted in Yellowstone rhyolites to construct a model for the evolution of Yellowstone's magmatic system from the caldera-forming eruption of the Lava Creek tuff at ca. 0.63 Ma to the present day. In particular

Relative Contribution of the Hydrogen 2 s Two-Photon Decay and Lyman- α Escape Channels during the Epoch of Cosmological Recombination

Science.gov (United States)

Rubiño-Martin, J. A.; Sunyaev, R. A.

2018-01-01

We discuss the evolution of the ratio in number of recombinations due to 2 s two photon escape and due to the escape of Lyman- α photons from the resonance during the epoch of cosmological recombination, within the width of the last scattering surface and near its boundaries. We discuss how this ratio evolves in time, and how it defines the profile of the Lyman- α line in the spectrum of CMB. One of the key reasons for explaining its time dependence is the strong overpopulation of the 2 p level relative to the 2 s level at redshifts z ≲ 750.

Linguistic Engineering and Linguistic of Engineering: Adaptation of Linguistic Paradigm for Circumstance of Engineering Epoch

OpenAIRE

Natalya Halina

2014-01-01

The article is devoted to the problems of linguistic knowledge in the Engineering Epoch. Engineering Epoch is the time of adaptation to the information flows by knowledge management, The system of adaptation mechanisms is connected with linguistic and linguistic technologies, forming in new linguistic patterns Linguistic Engineering and Linguistic of Engineering.

Convergent evolution in aquatic tetrapods: insights from an exceptional fossil mosasaur.

Directory of Open Access Journals (Sweden)

Johan Lindgren

Full Text Available Mosasaurs (family Mosasauridae are a diverse group of secondarily aquatic lizards that radiated into marine environments during the Late Cretaceous (98-65 million years ago. For the most part, they have been considered to be simple anguilliform swimmers--i.e., their propulsive force was generated by means of lateral undulations incorporating the greater part of the body--with unremarkable, dorsoventrally narrow tails and long, lizard-like bodies. Convergence with the specialized fusiform body shape and inferred carangiform locomotory style (in which only a portion of the posterior body participates in the thrust-producing flexure of ichthyosaurs and metriorhynchid crocodyliform reptiles, along with cetaceans, has so far only been recognized in Plotosaurus, the most highly derived member of the Mosasauridae. Here we report on an exceptionally complete specimen (LACM 128319 of the moderately derived genus Platecarpus that preserves soft tissues and anatomical details (e.g., large portions of integument, a partial body outline, putative skin color markings, a downturned tail, branching bronchial tubes, and probable visceral traces to an extent that has never been seen previously in any mosasaur. Our study demonstrates that a streamlined body plan and crescent-shaped caudal fin were already well established in Platecarpus, a taxon that preceded Plotosaurus by 20 million years. These new data expand our understanding of convergent evolution among marine reptiles, and provide insights into their evolution's tempo and mode.

The Cosmic Dawn and Epoch of Reionisation with SKA

NARCIS (Netherlands)

Koopmans, L.; Pritchard, J.; Mellema, G.; Aguirre, J.; Ahn, K.; Barkana, R.; van Bemmel, I.; Bernardi, G.; Bonaldi, A.; Briggs, F.; de Bruyn, A. G.; Chang, T. C.; Chapman, E.; Chen, X.; Ciardi, B.; Dayal, P.; Ferrara, A.; Fialkov, A.; Fiore, F.; Ichiki, K.; Illiev, I. T.; Inoue, S.; Jelic, V.; Jones, M.; Lazio, J.; Maio, U.; Majumdar, S.; Mack, K. J.; Mesinger, A.; Morales, M. F.; Parsons, A.; Pen, U. L.; Santos, M.; Schneider, R.; Semelin, B.; de Souza, R. S.; Subrahmanyan, R.; Takeuchi, T.; Vedantham, H.; Wagg, J.; Webster, R.; Wyithe, S.; Datta, K. K.; Trott, C.

2014-01-01

Concerted effort is currently ongoing to open up the Epoch of Reionization (EoR) ($z\\sim$15-6) for studies with IR and radio telescopes. Whereas IR detections have been made of sources (Lyman-$\\alpha$ emitters, quasars and drop-outs) in this redshift regime in relatively small fields of view, no

The Cosmic Dawn and Epoch of Reionisation with SKA

NARCIS (Netherlands)

Koopmans, L.; Pritchard, J.; Mellema, G.; Aguirre, J.; Ahn, K.; Barkana, R.; van Bemmel, I.; Bernardi, G.; Bonaldi, A.; Briggs, F.; de Bruyn, A. G.; Chang, T. C.; Chapman, E.; Chen, X.; Ciardi, B.; Dayal, P.; Ferrara, A.; Fialkov, A.; Fiore, F.; Ichiki, K.; Illiev, I. T.; Inoue, S.; Jelic, V.; Jones, M.; Lazio, J.; Maio, U.; Majumdar, S.; Mack, K. J.; Mesinger, A.; Morales, M. F.; Parsons, A.; Pen, U. L.; Santos, M.; Schneider, R.; Semelin, B.; de Souza, R. S.; Subrahmanyan, R.; Takeuchi, T.; Vedantham, H.; Wagg, J.; Webster, R.; Wyithe, S.; Datta, K. K.; Trott, C.

2015-01-01

Concerted effort is currently ongoing to open up the Epoch of Reionization (EoR) ($z\\sim$15-6) for studies with IR and radio telescopes. Whereas IR detections have been made of sources (Lyman-$\\alpha$ emitters, quasars and drop-outs) in this redshift regime in relatively small fields of view, no

Metallogenic epoch of the Jiapigou gold belt, Jilin Province, China

Indian Academy of Sciences (India)

Metallogenic epoch of the Jiapigou gold belt, Jilin Province, China: ... The Jiapigou gold belt is located on the northern margin of the North China Craton, and is one of the ... 29, Xueyuan Road, Beijing 100083, People's Republic of China.

A Lyman Break Galaxy in the Epoch of Reionization from Hubble Space Telescope (HST) Grism Spectroscopy

Science.gov (United States)

Rhoads, James E.; Malhotra, Sangeeta; Stern, Daniel K.; Gardner, Jonathan P.; Dickinson, Mark; Pirzkal, Norbert; Spinrad, Hyron; Reddy, Naveen; Dey, Arjun; Hathi, Nimish;

Gravitationally neutral dark matter-dark antimatter universe crystal with epochs of decelerated and accelerated expansion

Science.gov (United States)

Gribov, I. A.; Trigger, S. A.

2016-11-01

A large-scale self-similar crystallized phase of finite gravitationally neutral universe (GNU)—huge GNU-ball—with spherical 2D-boundary immersed into an endless empty 3D- space is considered. The main principal assumptions of this universe model are: (1) existence of stable elementary particles-antiparticles with the opposite gravitational “charges” (M+gr and M -gr), which have the same positive inertial mass M in = |M ±gr | ≥ 0 and are equally presented in the universe during all universe evolution epochs; (2) the gravitational interaction between the masses of the opposite charges” is repulsive; (3) the unbroken baryon-antibaryon symmetry; (4) M+gr-M-gr “charges” symmetry, valid for two equally presented matter-antimatter GNU-components: (a) ordinary matter (OM)-ordinary antimatter (OAM), (b) dark matter (DM)-dark antimatter (DAM). The GNU-ball is weightless crystallized dust of equally presented, mutually repulsive (OM+DM) clusters and (OAM+DAM) anticlusters. Newtonian GNU-hydrodynamics gives the observable spatial flatness and ideal Hubble flow. The GNU in the obtained large-scale self-similar crystallized phase preserves absence of the cluster-anticluster collisions and simultaneously explains the observable large-scale universe phenomena: (1) the absence of the matter-antimatter clusters annihilation, (2) the self-similar Hubble flow stability and homogeneity, (3) flatness, (4) bubble and cosmic-net structures as 3D-2D-1D decrystallization phases with decelerative (a ≤ 0) and accelerative (a ≥ 0) expansion epochs, (5) the dark energy (DE) phenomena with Λ VACUUM = 0, (6) the DE and DM fine-tuning nature and predicts (7) evaporation into isolated huge M±gr superclusters without Big Rip.

Gravitationally neutral dark matter–dark antimatter universe crystal with epochs of decelerated and accelerated expansion

International Nuclear Information System (INIS)

Gribov, I A; Trigger, S A

2016-01-01

A large-scale self-similar crystallized phase of finite gravitationally neutral universe (GNU)—huge GNU-ball—with spherical 2D-boundary immersed into an endless empty 3D- space is considered. The main principal assumptions of this universe model are: (1) existence of stable elementary particles-antiparticles with the opposite gravitational “charges” ( M + gr and M -gr ), which have the same positive inertial mass M in = | M ±gr | ≥ 0 and are equally presented in the universe during all universe evolution epochs; (2) the gravitational interaction between the masses of the opposite charges” is repulsive; (3) the unbroken baryon-antibaryon symmetry; (4) M +gr -M -gr “charges” symmetry, valid for two equally presented matter-antimatter GNU-components: (a) ordinary matter (OM)-ordinary antimatter (OAM), (b) dark matter (DM)-dark antimatter (DAM). The GNU-ball is weightless crystallized dust of equally presented, mutually repulsive (OM+DM) clusters and (OAM+DAM) anticlusters. Newtonian GNU-hydrodynamics gives the observable spatial flatness and ideal Hubble flow. The GNU in the obtained large-scale self-similar crystallized phase preserves absence of the cluster-anticluster collisions and simultaneously explains the observable large-scale universe phenomena: (1) the absence of the matter-antimatter clusters annihilation, (2) the self-similar Hubble flow stability and homogeneity, (3) flatness, (4) bubble and cosmic-net structures as 3D-2D-1D decrystallization phases with decelerative (a ≤ 0) and accelerative (a ≥ 0) expansion epochs, (5) the dark energy (DE) phenomena with Λ VACUUM = 0, (6) the DE and DM fine-tuning nature and predicts (7) evaporation into isolated huge M ±gr superclusters without Big Rip. (paper)

Pliocene geomagnetic polarity epochs

Science.gov (United States)

Dalrymple, G.B.; Cox, A.; Doell, Richard R.; Gromme, C.S.

1967-01-01

A paleomagnetic and K-Ar dating study of 44 upper Miocene and Pliocene volcanic units from the western United States suggests that the frequency of reversals of the earth's magnetic field during Pliocene time may have been comparable with that of the last 3.6 m.y. Although the data are too limited to permit the formal naming of any new polarity epochs or events, four polarity transitions have been identified: the W10 R/N boundary at 3.7 ?? 0.1 m.y., the A12 N/R boundary at 4.9 ?? 0.1 m.y., the W32 N/R boundary at 9.0 ?? 0.2m.y., and the W36 R/N boundary at 10.8 ?? 0.3 - 1.0 m.y. The loss of absolute resolution of K-Ar dating in older rocks indicates that the use of well defined stratigraphic successions to identify and date polarity transitions will be important in the study of Pliocene and older reversals. ?? 1967.

The evolution of helical cosmic magnetic fields as predicted by MHD closure theory

Energy Technology Data Exchange (ETDEWEB)

Saveliev, Andrey; Sigl, Guenter [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Jedamzik, Kartsen [Univ. Montpellier-2. (France). Laboratoire Univers et Particules de Montpellier

2013-04-15

We extend our recent derivation of the time evolution equations for the energy content of magnetic fields and turbulent motions for incompressible, homogeneous, and isotropic turbulence to include the case of non-vanishing helicity. These equations are subsequently numerically integrated in order to predict the present day primordial magnetic field strength and correlation length, depending on its initial helicity and magnetic energy density. We find that all prior analytic predictions for helical magnetic fields, such as the epoch when they become maximally helical and their subsequent growth of correlation length L {proportional_to} a{sup 1/3} and decrease of magnetic field strength B {proportional_to} a{sup -1/3} with scale factor a are well confirmed by the simulations. An initially fully helical primordial magnetic field is a factor 4 x 10{sup 4} stronger at the present epoch then its non-helical counterpart when generated during the electroweak epoch.

Evolution of Rhizaria: new insights from phylogenomic analysis of uncultivated protists.

Science.gov (United States)

Burki, Fabien; Kudryavtsev, Alexander; Matz, Mikhail V; Aglyamova, Galina V; Bulman, Simon; Fiers, Mark; Keeling, Patrick J; Pawlowski, Jan

2010-12-02

work reveals another possible rhizarian signature in the 60S ribosomal protein L10a. Our study provides new insights into the evolution of Rhizaria based on phylogenomic analyses of ESTs from three groups of previously under-sampled protists. It was enabled through the application of a recently developed method of transcriptome analysis, requiring very small amount of starting material. Our study illustrates the potential of this method to elucidate the early evolution of eukaryotes by providing large amount of data for uncultivable free-living and parasitic protists.

Evolution of Rhizaria: new insights from phylogenomic analysis of uncultivated protists

Directory of Open Access Journals (Sweden)

Bulman Simon

2010-12-01

insertion in Acantharea. Finally, this work reveals another possible rhizarian signature in the 60S ribosomal protein L10a. Conclusions Our study provides new insights into the evolution of Rhizaria based on phylogenomic analyses of ESTs from three groups of previously under-sampled protists. It was enabled through the application of a recently developed method of transcriptome analysis, requiring very small amount of starting material. Our study illustrates the potential of this method to elucidate the early evolution of eukaryotes by providing large amount of data for uncultivable free-living and parasitic protists.

Insight as a social identity process in the evolution of psychosocial functioning in the early phase of psychosis.

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Klaas, H S; Clémence, A; Marion-Veyron, R; Antonietti, J-P; Alameda, L; Golay, P; Conus, P

2017-03-01

Awareness of illness (insight) has been found to have contradictory effects for different functional outcomes after the early course of psychosis. Whereas it is related to psychotic symptom reduction and medication adherence, it is also associated with increased depressive symptoms. In this line, the specific effects of insight on the evolution of functioning over time have not been identified, and social indicators, such as socio-occupational functioning have barely been considered. Drawing from social identity theory we investigated the impact of insight on the development of psychosocial outcomes and the interactions of these variables over time. The participants, 240 patients in early phase of psychosis from the Treatment and Early Intervention in Psychosis Program (TIPP) of the University Hospital of Lausanne, Switzerland, were assessed at eight time points over 3 years. Cross-lagged panel analyses and multilevel analyses were conducted on socio-occupational and general functioning [Social and Occupational Functioning Assessment Scale (SOFAS) and Global Assessment of Functioning (GAF)] with insight, time and depressive symptoms as independent variables. Results from multilevel analyses point to an overall positive impact of insight on psychosocial functioning, which increases over time. Yet the cross-lagged panel analysis did not reveal a systematic positive and causal effect of insight on SOFAS and GAF scores. Depressive symptoms seem only to be relevant in the beginning of the treatment process. Our results point to a complex process in which the positive impact of insight on psychosocial functioning increases over time, even when considering depressive symptoms. Future studies and treatment approaches should consider the procedural aspect of insight.

Insights into the Evolution of Hydroxyproline-Rich Glycoproteins from 1000 Plant Transcriptomes.

Science.gov (United States)

Johnson, Kim L; Cassin, Andrew M; Lonsdale, Andrew; Wong, Gane Ka-Shu; Soltis, Douglas E; Miles, Nicholas W; Melkonian, Michael; Melkonian, Barbara; Deyholos, Michael K; Leebens-Mack, James; Rothfels, Carl J; Stevenson, Dennis W; Graham, Sean W; Wang, Xumin; Wu, Shuangxiu; Pires, J Chris; Edger, Patrick P; Carpenter, Eric J; Bacic, Antony; Doblin, Monika S; Schultz, Carolyn J

2017-06-01

The carbohydrate-rich cell walls of land plants and algae have been the focus of much interest given the value of cell wall-based products to our current and future economies. Hydroxyproline-rich glycoproteins (HRGPs), a major group of wall glycoproteins, play important roles in plant growth and development, yet little is known about how they have evolved in parallel with the polysaccharide components of walls. We investigate the origins and evolution of the HRGP superfamily, which is commonly divided into three major multigene families: the arabinogalactan proteins (AGPs), extensins (EXTs), and proline-rich proteins. Using motif and amino acid bias, a newly developed bioinformatics pipeline, we identified HRGPs in sequences from the 1000 Plants transcriptome project (www.onekp.com). Our analyses provide new insights into the evolution of HRGPs across major evolutionary milestones, including the transition to land and the early radiation of angiosperms. Significantly, data mining reveals the origin of glycosylphosphatidylinositol (GPI)-anchored AGPs in green algae and a 3- to 4-fold increase in GPI-AGPs in liverworts and mosses. The first detection of cross-linking (CL)-EXTs is observed in bryophytes, which suggests that CL-EXTs arose though the juxtaposition of preexisting SP n EXT glycomotifs with refined Y-based motifs. We also detected the loss of CL-EXT in a few lineages, including the grass family (Poaceae), that have a cell wall composition distinct from other monocots and eudicots. A key challenge in HRGP research is tracking individual HRGPs throughout evolution. Using the 1000 Plants output, we were able to find putative orthologs of Arabidopsis pollen-specific GPI-AGPs in basal eudicots. © 2017 American Society of Plant Biologists. All Rights Reserved.

Chemical evolution of the galactic disk

International Nuclear Information System (INIS)

Wyse, R.F.G.; Gilmore, G.

1987-01-01

The distribution of enriched material in the stars and gas of their Galaxy contains information pertaining to the chemical evolution of the Milky Way from its formation epoch to the present day, and provides general constraints on theories of galaxy formation. The separate stellar components of the Galaxy cannot readily be understood if treated in isolation, but a reasonably self-consistent model for Galactic chemical evolution may be found if one considers together the chemical properties of the extreme spheroid, thick disk and thin disk populations of the Galaxy. The three major stellar components of the Galaxy are characterized by their distinct spatial distributions, metallicity structure, and kinematics, with the newly-identified thick disk being approximately three times more massive than the classical metal-poor, non-rotating extreme spheroid. Stellar evolution in the thick disk straightforwardly provides the desired pre-enrichment for resolution of the thin disk G dwarf problem

LSST and the Epoch of Reionization Experiments

Science.gov (United States)

Ivezić, Željko

2018-05-01

The Large Synoptic Survey Telescope (LSST), a next generation astronomical survey, sited on Cerro Pachon in Chile, will provide an unprecedented amount of imaging data for studies of the faint optical sky. The LSST system includes an 8.4m (6.7m effective) primary mirror and a 3.2 Gigapixel camera with a 9.6 sq. deg. field of view. This system will enable about 10,000 sq. deg. of sky to be covered twice per night, every three to four nights on average, with typical 5-sigma depth for point sources of r = 24.5 (AB). With over 800 observations in the ugrizy bands over a 10-year period, these data will enable coadded images reaching r = 27.5 (about 5 magnitudes deeper than SDSS) as well as studies of faint time-domain astronomy. The measured properties of newly discovered and known astrometric and photometric transients will be publicly reported within 60 sec after closing the shutter. The resulting hundreds of petabytes of imaging data for about 40 billion objects will be used for scientific investigations ranging from the properties of near-Earth asteroids to characterizations of dark matter and dark energy. For example, simulations estimate that LSST will discover about 1,000 quasars at redshifts exceeding 7; this sample will place tight constraints on the cosmic environment at the end of the reionization epoch. In addition to a brief introduction to LSST, I review the value of LSST data in support of epoch of reionization experiments and discuss how international participants can join LSST.

Principles of evolution from the Planck epoch to complex multicellular life

CERN Document Server

Meyer-Ortmanns, Hildegard

2011-01-01

With contributions from a team of leading experts, this volume provides a comprehensive survey of recent achievements in our scientific understanding of evolution. The questions it asks concern the beginnings of the universe, the origin of life and the chances of its arising at all, the role of contingency, and the search for universal features in the plethora of evolutionary phenomena. Rather than oversimplified or premature answers, the chapters provide a clear picture of how these essential problems are being tackled, enabling the reader to understand current thinking and open questions.  The tools employed stem from a range of disciplines including mathematics, physics, biochemistry and cell biology. Self-organization as an overarching concept is demonstrated in the most diverse areas: from galaxy formation in the universe to spindle and aster formation in the cell. Chemical master equations, population dynamics, and evolutionary game theory are presented as suitable frameworks for understanding the univ...

Evolution-development congruence in pattern formation dynamics: Bifurcations in gene expression and regulation of networks structures.

Science.gov (United States)

Kohsokabe, Takahiro; Kaneko, Kunihiko

2016-01-01

Search for possible relationships between phylogeny and ontogeny is important in evolutionary-developmental biology. Here we uncover such relationships by numerical evolution and unveil their origin in terms of dynamical systems theory. By representing developmental dynamics of spatially located cells with gene expression dynamics with cell-to-cell interaction under external morphogen gradient, gene regulation networks are evolved under mutation and selection with the fitness to approach a prescribed spatial pattern of expressed genes. For most numerical evolution experiments, evolution of pattern over generations and development of pattern by an evolved network exhibit remarkable congruence. Both in the evolution and development pattern changes consist of several epochs where stripes are formed in a short time, while for other temporal regimes, pattern hardly changes. In evolution, these quasi-stationary regimes are generations needed to hit relevant mutations, while in development, they are due to some gene expression that varies slowly and controls the pattern change. The morphogenesis is regulated by combinations of feedback or feedforward regulations, where the upstream feedforward network reads the external morphogen gradient, and generates a pattern used as a boundary condition for the later patterns. The ordering from up to downstream is common in evolution and development, while the successive epochal changes in development and evolution are represented as common bifurcations in dynamical-systems theory, which lead to the evolution-development congruence. Mechanism of exceptional violation of the congruence is also unveiled. Our results provide a new look on developmental stages, punctuated equilibrium, developmental bottlenecks, and evolutionary acquisition of novelty in morphogenesis. © 2015 The Authors. Journal of Experimental Zoology Part B: Molecular and Developmental Evolution Published by Wiley Periodicals, Inc.

Period, epoch, and prediction errors of ephemerides from continuous sets of timing measurements

Science.gov (United States)

Deeg, H. J.

2015-06-01

Space missions such as Kepler and CoRoT have led to large numbers of eclipse or transit measurements in nearly continuous time series. This paper shows how to obtain the period error in such measurements from a basic linear least-squares fit, and how to correctly derive the timing error in the prediction of future transit or eclipse events. Assuming strict periodicity, a formula for the period error of these time series is derived, σP = σT (12 / (N3-N))1 / 2, where σP is the period error, σT the timing error of a single measurement, and N the number of measurements. Compared to the iterative method for period error estimation by Mighell & Plavchan (2013), this much simpler formula leads to smaller period errors, whose correctness has been verified through simulations. For the prediction of times of future periodic events, usual linear ephemeris were epoch errors are quoted for the first time measurement, are prone to an overestimation of the error of that prediction. This may be avoided by a correction for the duration of the time series. An alternative is the derivation of ephemerides whose reference epoch and epoch error are given for the centre of the time series. For long continuous or near-continuous time series whose acquisition is completed, such central epochs should be the preferred way for the quotation of linear ephemerides. While this work was motivated from the analysis of eclipse timing measures in space-based light curves, it should be applicable to any other problem with an uninterrupted sequence of discrete timings for which the determination of a zero point, of a constant period and of the associated errors is needed.

Insights into Mercury's Core Evolution from the Thermodynamic Properties of Fe-S-Si

Science.gov (United States)

Edgington, A.; Vocadlo, L.; Stixrude, L. P.; Wood, I. G.; Lord, O. T.

2015-12-01

The structure, composition and evolution of Mercury, the innermost planet, are puzzling, as its high uncompressed density implies a body highly enriched in metallic iron, whilst the existence of Mercury's magnetic field and observations of its longitude librations [1] suggest at least a partially molten core. This study uses a combination of experimental and ab-initio computer simulation techniques to determine the properties of Fe-S-Si (relative atomic percentages, 80:10:10) throughout the conditions of the interior of the planet Mercury, and evaluates the implications of this material for the structure and evolution of the planet's core. Previous studies have considered the addition of sulphur to the pure iron system, as this can significantly depress the melting curve of iron, and so may possibly allow Mercury's core to remain molten to the present day [2]. However, important constraints placed by the MESSENGER spacecraft on Mercury's surface abundance of iron [3] suggest that the planet formed in highly reduced conditions, in which significant amounts of silicon could have also dissolved into the core [4]. First-principles molecular dynamics simulations of the thermodynamic properties of liquid Fe-S-Si, alongside laser-heated diamond-anvil-cell experiments to determine the melting behaviour of the same composition, reveal the slopes of the adiabatic gradient and melting curve respectively, which together may allow insight into the evolution of our solar system's smallest planet. [1] Margot, J. L. et al. (2007) Science, 316: 710-714[2] Schubert, G. et al. (1988) in 'Mercury' 429-460[3] Nittler, L. R. et al. (2011) Science, 333, 1847-1850[4] Malavergne, V. et al. (2010) Icarus, 206:199-209

Expanding the Diversity of Mycobacteriophages: Insights into Genome Architecture and Evolution

Science.gov (United States)

Pope, Welkin H.; Jacobs-Sera, Deborah; Russell, Daniel A.; Peebles, Craig L.; Al-Atrache, Zein; Alcoser, Turi A.; Alexander, Lisa M.; Alfano, Matthew B.; Alford, Samantha T.; Amy, Nichols E.; Anderson, Marie D.; Anderson, Alexander G.; Ang, Andrew A. S.; Ares, Manuel; Barber, Amanda J.; Barker, Lucia P.; Barrett, Jonathan M.; Barshop, William D.; Bauerle, Cynthia M.; Bayles, Ian M.; Belfield, Katherine L.; Best, Aaron A.; Borjon, Agustin; Bowman, Charles A.; Boyer, Christine A.; Bradley, Kevin W.; Bradley, Victoria A.; Broadway, Lauren N.; Budwal, Keshav; Busby, Kayla N.; Campbell, Ian W.; Campbell, Anne M.; Carey, Alyssa; Caruso, Steven M.; Chew, Rebekah D.; Cockburn, Chelsea L.; Cohen, Lianne B.; Corajod, Jeffrey M.; Cresawn, Steven G.; Davis, Kimberly R.; Deng, Lisa; Denver, Dee R.; Dixon, Breyon R.; Ekram, Sahrish; Elgin, Sarah C. R.; Engelsen, Angela E.; English, Belle E. V.; Erb, Marcella L.; Estrada, Crystal; Filliger, Laura Z.; Findley, Ann M.; Forbes, Lauren; Forsyth, Mark H.; Fox, Tyler M.; Fritz, Melissa J.; Garcia, Roberto; George, Zindzi D.; Georges, Anne E.; Gissendanner, Christopher R.; Goff, Shannon; Goldstein, Rebecca; Gordon, Kobie C.; Green, Russell D.; Guerra, Stephanie L.; Guiney-Olsen, Krysta R.; Guiza, Bridget G.; Haghighat, Leila; Hagopian, Garrett V.; Harmon, Catherine J.; Harmson, Jeremy S.; Hartzog, Grant A.; Harvey, Samuel E.; He, Siping; He, Kevin J.; Healy, Kaitlin E.; Higinbotham, Ellen R.; Hildebrandt, Erin N.; Ho, Jason H.; Hogan, Gina M.; Hohenstein, Victoria G.; Holz, Nathan A.; Huang, Vincent J.; Hufford, Ericka L.; Hynes, Peter M.; Jackson, Arrykka S.; Jansen, Erica C.; Jarvik, Jonathan; Jasinto, Paul G.; Jordan, Tuajuanda C.; Kasza, Tomas; Katelyn, Murray A.; Kelsey, Jessica S.; Kerrigan, Larisa A.; Khaw, Daryl; Kim, Junghee; Knutter, Justin Z.; Ko, Ching-Chung; Larkin, Gail V.; Laroche, Jennifer R.; Latif, Asma; Leuba, Kohana D.; Leuba, Sequoia I.; Lewis, Lynn O.; Loesser-Casey, Kathryn E.; Long, Courtney A.; Lopez, A. Javier; Lowery, Nicholas; Lu, Tina Q.; Mac, Victor; Masters, Isaac R.; McCloud, Jazmyn J.; McDonough, Molly J.; Medenbach, Andrew J.; Menon, Anjali; Miller, Rachel; Morgan, Brandon K.; Ng, Patrick C.; Nguyen, Elvis; Nguyen, Katrina T.; Nguyen, Emilie T.; Nicholson, Kaylee M.; Parnell, Lindsay A.; Peirce, Caitlin E.; Perz, Allison M.; Peterson, Luke J.; Pferdehirt, Rachel E.; Philip, Seegren V.; Pogliano, Kit; Pogliano, Joe; Polley, Tamsen; Puopolo, Erica J.; Rabinowitz, Hannah S.; Resiss, Michael J.; Rhyan, Corwin N.; Robinson, Yetta M.; Rodriguez, Lauren L.; Rose, Andrew C.; Rubin, Jeffrey D.; Ruby, Jessica A.; Saha, Margaret S.; Sandoz, James W.; Savitskaya, Judith; Schipper, Dale J.; Schnitzler, Christine E.; Schott, Amanda R.; Segal, J. Bradley; Shaffer, Christopher D.; Sheldon, Kathryn E.; Shepard, Erica M.; Shepardson, Jonathan W.; Shroff, Madav K.; Simmons, Jessica M.; Simms, Erika F.; Simpson, Brandy M.; Sinclair, Kathryn M.; Sjoholm, Robert L.; Slette, Ingrid J.; Spaulding, Blaire C.; Straub, Clark L.; Stukey, Joseph; Sughrue, Trevor; Tang, Tin-Yun; Tatyana, Lyons M.; Taylor, Stephen B.; Taylor, Barbara J.; Temple, Louise M.; Thompson, Jasper V.; Tokarz, Michael P.; Trapani, Stephanie E.; Troum, Alexander P.; Tsay, Jonathan; Tubbs, Anthony T.; Walton, Jillian M.; Wang, Danielle H.; Wang, Hannah; Warner, John R.; Weisser, Emilie G.; Wendler, Samantha C.; Weston-Hafer, Kathleen A.; Whelan, Hilary M.; Williamson, Kurt E.; Willis, Angelica N.; Wirtshafter, Hannah S.; Wong, Theresa W.; Wu, Phillip; Yang, Yun jeong; Yee, Brandon C.; Zaidins, David A.; Zhang, Bo; Zúniga, Melina Y.; Hendrix, Roger W.; Hatfull, Graham F.

2011-01-01

Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However, their genetic diversity is considerable, and although sixty-two genomes have been sequenced and comparatively analyzed, these likely represent only a small portion of the diversity of the mycobacteriophage population at large. Here we report the isolation, sequencing and comparative genomic analysis of 18 new mycobacteriophages isolated from geographically distinct locations within the United States. Although no clear correlation between location and genome type can be discerned, these genomes expand our knowledge of mycobacteriophage diversity and enhance our understanding of the roles of mobile elements in viral evolution. Expansion of the number of mycobacteriophages grouped within Cluster A provides insights into the basis of immune specificity in these temperate phages, and we also describe a novel example of apparent immunity theft. The isolation and genomic analysis of bacteriophages by freshman college students provides an example of an authentic research experience for novice scientists. PMID:21298013

Expanding the diversity of mycobacteriophages: insights into genome architecture and evolution.

Directory of Open Access Journals (Sweden)

Welkin H Pope

2011-01-01

Full Text Available Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes. However, their genetic diversity is considerable, and although sixty-two genomes have been sequenced and comparatively analyzed, these likely represent only a small portion of the diversity of the mycobacteriophage population at large. Here we report the isolation, sequencing and comparative genomic analysis of 18 new mycobacteriophages isolated from geographically distinct locations within the United States. Although no clear correlation between location and genome type can be discerned, these genomes expand our knowledge of mycobacteriophage diversity and enhance our understanding of the roles of mobile elements in viral evolution. Expansion of the number of mycobacteriophages grouped within Cluster A provides insights into the basis of immune specificity in these temperate phages, and we also describe a novel example of apparent immunity theft. The isolation and genomic analysis of bacteriophages by freshman college students provides an example of an authentic research experience for novice scientists.

What next-generation 21 cm power spectrum measurements can teach us about the epoch of reionization

International Nuclear Information System (INIS)

Pober, Jonathan C.; Morales, Miguel F.; Liu, Adrian; McQuinn, Matthew; Parsons, Aaron R.; Dillon, Joshua S.; Hewitt, Jacqueline N.; Tegmark, Max; Aguirre, James E.; Bowman, Judd D.; Jacobs, Daniel C.; Bradley, Richard F.; Carilli, Chris L.; DeBoer, David R.; Werthimer, Dan J.

2014-01-01

A number of experiments are currently working toward a measurement of the 21 cm signal from the epoch of reionization (EoR). Whether or not these experiments deliver a detection of cosmological emission, their limited sensitivity will prevent them from providing detailed information about the astrophysics of reionization. In this work, we consider what types of measurements will be enabled by the next generation of larger 21 cm EoR telescopes. To calculate the type of constraints that will be possible with such arrays, we use simple models for the instrument, foreground emission, and the reionization history. We focus primarily on an instrument modeled after the ∼0.1 km 2 collecting area Hydrogen Epoch of Reionization Array concept design and parameterize the uncertainties with regard to foreground emission by considering different limits to the recently described 'wedge' footprint in k space. Uncertainties in the reionization history are accounted for using a series of simulations that vary the ionizing efficiency and minimum virial temperature of the galaxies responsible for reionization, as well as the mean free path of ionizing photons through the intergalactic medium. Given various combinations of models, we consider the significance of the possible power spectrum detections, the ability to trace the power spectrum evolution versus redshift, the detectability of salient power spectrum features, and the achievable level of quantitative constraints on astrophysical parameters. Ultimately, we find that 0.1 km 2 of collecting area is enough to ensure a very high significance (≳ 30σ) detection of the reionization power spectrum in even the most pessimistic scenarios. This sensitivity should allow for meaningful constraints on the reionization history and astrophysical parameters, especially if foreground subtraction techniques can be improved and successfully implemented.

The epochs of international law

CERN Document Server

Grewe, Wilhelm G

2000-01-01

A theoretical overview and detailed analysis of the history of international law from the Middle Ages through to the end of the twentieth century (updated from the 1984 German language edition). Wilhelm Grewe's "Epochen der Völkerrechtsgeschichte" is widely regarded as one of the classic twentieth century works of international law. This revised translation by Michael Byers of Oxford University makes this important book available to non-German readers for the first time. "The Epochs of International Law" provides a theoretical overview and detailed analysis of the history of international law from the Middle Ages, to the Age of Discovery and the Thirty Years War, from Napoleon Bonaparte to the Treaty of Versailles and the Age of the Single Superpower, and does so in a way that reflects Grewe's own experience as one of Germany's leading diplomats and professors of international law. A new chapter, written by Wilhelm Grewe and Michael Byers, updates the book to 1998, making the revised translation of interest ...

Spider genomes provide insight into composition and evolution of venom and silk

Science.gov (United States)

Sanggaard, Kristian W.; Bechsgaard, Jesper S.; Fang, Xiaodong; Duan, Jinjie; Dyrlund, Thomas F.; Gupta, Vikas; Jiang, Xuanting; Cheng, Ling; Fan, Dingding; Feng, Yue; Han, Lijuan; Huang, Zhiyong; Wu, Zongze; Liao, Li; Settepani, Virginia; Thøgersen, Ida B.; Vanthournout, Bram; Wang, Tobias; Zhu, Yabing; Funch, Peter; Enghild, Jan J.; Schauser, Leif; Andersen, Stig U.; Villesen, Palle; Schierup, Mikkel H; Bilde, Trine; Wang, Jun

2014-01-01

Spiders are ecologically important predators with complex venom and extraordinarily tough silk that enables capture of large prey. Here we present the assembled genome of the social velvet spider and a draft assembly of the tarantula genome that represent two major taxonomic groups of spiders. The spider genomes are large with short exons and long introns, reminiscent of mammalian genomes. Phylogenetic analyses place spiders and ticks as sister groups supporting polyphyly of the Acari. Complex sets of venom and silk genes/proteins are identified. We find that venom genes evolved by sequential duplication, and that the toxic effect of venom is most likely activated by proteases present in the venom. The set of silk genes reveals a highly dynamic gene evolution, new types of silk genes and proteins, and a novel use of aciniform silk. These insights create new opportunities for pharmacological applications of venom and biomaterial applications of silk. PMID:24801114

Masticatory muscle architecture in the Laotian rock rat Laonastes aenigmamus (Mammalia, Rodentia): new insights into the evolution of hystricognathy.

Science.gov (United States)

Hautier, Lionel; Saksiri, Soonchan

2009-10-01

We present the first descriptive comparison of the skull, mandible and jaw muscles of the recently recovered Laotian rock rat Laonastes aenigmamus. The gross anatomy of five specimens captured in Laos and internal architecture of the jaw musculature were studied using dissections. The following muscles are described: temporal, masseter, pterygoids, digastric, mylohyoid, geniohyoid and transverse mandibular. The description of the masticatory apparatus of L. aenigmamus offers a rare opportunity to assess the order of establishment of the morphological characters during the evolution of Ctenohystrica. Striking convergences have occurred during the evolution of Diatomyidae and L. aenigmamus presents a unique combination of myological features that corresponds to a mixture of sciurognathous and hystricognathous characters. If L. aenigmamus is a sciurognathous rodent, we have to assume that it independently acquired a pars reflexa of the superficial masseter. We show for the first time that the development of this pars reflexa has occurred several times during the evolution of Ctenohystrica and can no longer be considered a synapomorphic feature of 'Hystricognathi'. These results bring new insights into the evolution of hystricognathy and have profound implications for the interpretation of the fossil record of early hystricognath rodents.

Surprise in simplicity: an unusual spectral evolution of a single pulse GRB 151006A

Science.gov (United States)

Basak, R.; Iyyani, S.; Chand, V.; Chattopadhyay, T.; Bhattacharya, D.; Rao, A. R.; Vadawale, S. V.

2017-11-01

We present a detailed analysis of GRB 151006A, the first gamma-ray burst (GRB) detected by AstroSat Cadmium-Zinc-Telluride Imager (CZTI). We study the long-term spectral evolution by exploiting the capabilities of Fermi and Swift satellites at different phases, which is complemented by the polarization measurement with the CZTI. While the light curve of the GRB in different energy bands shows a simple pulse profile, the spectrum shows an unusual evolution. The first phase exhibits a hard-to-soft evolution until ∼16-20 s, followed by a sudden increase in the spectral peak reaching a few MeV. Such a dramatic change in the spectral evolution in the case of a single pulse burst is reported for the first time. This is captured by all models we used namely, Band function, blackbody+Band and two blackbodies+power law. Interestingly, the Fermi Large Area Telescope also detects its first photon (>100 MeV) during this time. This new injection of energy may be associated with either the beginning of afterglow phase, or a second hard pulse of the prompt emission itself that, however, is not seen in the otherwise smooth pulse profile. By constructing Bayesian blocks and studying the hardness evolution we find a good evidence for a second hard pulse. The Swift data at late epochs (>T90 of the GRB) also show a significant spectral evolution consistent with the early second phase. The CZTI data (100-350 keV), though having low significance (1σ), show high values of polarization in the two epochs (77-94 per cent), in agreement with our interpretation.

A Comparative Genomic Survey Provides Novel Insights into Molecular Evolution of l-Aromatic Amino Acid Decarboxylase in Vertebrates

Directory of Open Access Journals (Sweden)

Yanping Li

2018-04-01

Full Text Available Melatonin is a pleiotropic molecule with various important physiological roles in vertebrates. l-aromatic amino acid decarboxylase (AAAD is the second enzyme for melatonin synthesis. By far, a clear-cut gene function of AAAD in the biosynthesis of melatonin has been unclear in vertebrates. Here, we provide novel insights into the evolution of AAAD based on 77 vertebrate genomes. According to our genome-wide alignments, we extracted a total of 151 aaad nucleotide sequences. A phylogenetic tree was constructed on the basis of these sequences and corresponding protein alignments, indicating that tetrapods and diploid bony fish genomes contained one aaad gene and a new aaad-like gene, which formed a novel AAAD family. However, in tetraploid teleosts, there were two copies of the aaad gene due to whole genome duplication. A subsequent synteny analysis investigated 81 aaad sequences and revealed their collinearity and systematic evolution. Interestingly, we discovered that platypus (Ornithorhynchus anatinus, Atlantic cod (Guadus morhua, Mexican tetra (Astyanax mexicanus, and a Sinocyclocheilus cavefish (S. anshuiensis have long evolutionary branches in the phylogenetic topology. We also performed pseudogene identification and selection pressure analysis; however, the results revealed a deletion of 37 amino acids in Atlantic cod and premature stop codons in the cave-restricted S. anshuiensis and A. mexicanus, suggesting weakening or disappearing rhythms in these cavefishes. Selective pressure analysis of aaad between platypus and other tetrapods showed that rates of nonsynonymous (Ka and synonymous (Ks substitutions were higher when comparing the platypus to other representative tetrapods, indicating that, in this semiaquatic mammal, the aaad gene experienced selection during the process of evolution. In summary, our current work provides novel insights into aaad genes in vertebrates from a genome-wide view.

Genomes and geography: genomic insights into the evolution and phylogeography of the genus Schistosoma

Directory of Open Access Journals (Sweden)

Ironside Joe E

2011-07-01

Full Text Available Abstract Blood flukes within the genus Schistosoma still remain a major cause of disease in the tropics and subtropics and the study of their evolution has been an area of major debate and research. With the advent of modern molecular and genomic approaches deeper insights have been attained not only into the divergence and speciation of these worms, but also into the historic movement of these parasites from Asia into Africa, via migration and dispersal of definitive and snail intermediate hosts. This movement was subsequently followed by a radiation of Schistosoma species giving rise to the S. mansoni and S. haematobium groups, as well as the S. indicum group that reinvaded Asia. Each of these major evolutionary events has been marked by distinct changes in genomic structure evident in differences in mitochondrial gene order and nuclear chromosomal architecture between the species associated with Asia and Africa. Data from DNA sequencing, comparative molecular genomics and karyotyping are indicative of major constitutional genomic events which would have become fixed in the ancestral populations of these worms. Here we examine how modern genomic techniques may give a more in depth understanding of the evolution of schistosomes and highlight the complexity of speciation and divergence in this group.

Effects of Varying Epoch Lengths, Wear Time Algorithms, and Activity Cut-Points on Estimates of Child Sedentary Behavior and Physical Activity from Accelerometer Data.

Science.gov (United States)

Banda, Jorge A; Haydel, K Farish; Davila, Tania; Desai, Manisha; Bryson, Susan; Haskell, William L; Matheson, Donna; Robinson, Thomas N

2016-01-01

To examine the effects of accelerometer epoch lengths, wear time (WT) algorithms, and activity cut-points on estimates of WT, sedentary behavior (SB), and physical activity (PA). 268 7-11 year-olds with BMI ≥ 85th percentile for age and sex wore accelerometers on their right hips for 4-7 days. Data were processed and analyzed at epoch lengths of 1-, 5-, 10-, 15-, 30-, and 60-seconds. For each epoch length, WT minutes/day was determined using three common WT algorithms, and minutes/day and percent time spent in SB, light (LPA), moderate (MPA), and vigorous (VPA) PA were determined using five common activity cut-points. ANOVA tested differences in WT, SB, LPA, MPA, VPA, and MVPA when using the different epoch lengths, WT algorithms, and activity cut-points. WT minutes/day varied significantly by epoch length when using the NHANES WT algorithm (p algorithms. Minutes/day and percent time spent in SB, LPA, MPA, VPA, and MVPA varied significantly by epoch length for all sets of activity cut-points tested with all three WT algorithms (all p algorithms (all p algorithms and activity cut-point definitions to match different epoch lengths may introduce significant errors. Estimates of SB and PA from studies that process and analyze data using different epoch lengths, WT algorithms, and/or activity cut-points are not comparable, potentially leading to very different results, interpretations, and conclusions, misleading research and public policy.

Multi-epoch VLBA Imaging of 20 New TeV Blazars: Apparent Jet Speeds

Science.gov (United States)

Piner, B. Glenn; Edwards, Philip G.

2018-01-01

We present 88 multi-epoch Very Long Baseline Array (VLBA) images (most at an observing frequency of 8 GHz) of 20 TeV blazars, all of the high-frequency-peaked BL Lac (HBL) class, that have not been previously studied at multiple epochs on the parsec scale. From these 20 sources, we analyze the apparent speeds of 43 jet components that are all detected at four or more epochs. As has been found for other TeV HBLs, the apparent speeds of these components are relatively slow. About two-thirds of the components have an apparent speed that is consistent (within 2σ) with no motion, and some of these components may be stationary patterns whose apparent speed does not relate to the underlying bulk flow speed. In addition, a superluminal tail to the apparent speed distribution of the TeV HBLs is detected for the first time, with eight components in seven sources having a 2σ lower limit on the apparent speed exceeding 1c. We combine the data from these 20 sources with an additional 18 sources from the literature to analyze the complete apparent speed distribution of all 38 TeV HBLs that have been studied with very long baseline interferometry at multiple epochs. The highest 2σ apparent speed lower limit considering all sources is 3.6c. This suggests that bulk Lorentz factors of up to about 4, but probably not much higher, exist in the parsec-scale radio-emitting regions of these sources, consistent with estimates obtained in the radio by other means such as brightness temperatures. This can be reconciled with the high Lorentz factors estimated from the high-energy data if the jet has velocity structures consisting of different emission regions with different Lorentz factors. In particular, we analyze the current apparent speed data for the TeV HBLs in the context of a model with a fast central spine and a slower outer layer.

Widely available active sites on Ni2P for electrochemical hydrogen evolution - insights from first principles calculations

DEFF Research Database (Denmark)

Hansen, Martin Hangaard; Stern, Lucas-Alexandre; Feng, Ligang

2015-01-01

We present insights into the mechanism and the active site for hydrogen evolution on nickel phosphide (Ni2P). Ni2P was recently discovered to be a very active non-precious hydrogen evolution catalyst. Current literature attributes the activity of Ni2P to a particular site on the (0001) facet....... In the present study, using Density Functional Theory (DFT) calculations, we show that several widely available low index crystal facets on Ni2P have better properties for a high catalytic activity. DFT calculations were used to identify moderately bonding nickel bridge sites and nickel hollow sites for hydrogen...... adsorption and to calculate barriers for the Tafel pathway. The investigated surfaces in this study were the (10 (1) over bar0), ((1) over bar(1) over bar 20), (11 (2) over bar0), (11 (2) over bar1) and (0001) facets of the hexagonal Ni2P crystal. In addition to the DFT results, we present experiments on Ni2...

New insights on early evolution of spiny-rayed fishes (Teleostei: Acanthomorpha

Directory of Open Access Journals (Sweden)

Wei-Jen eChen

2014-10-01

Full Text Available The Acanthomorpha is the largest group of teleost fishes with about one third of extant vertebrate species. In the course of its evolution this lineage experienced several episodes of radiation, leading to a large number of descendant lineages differing profoundly in morphology, ecology, distribution and behavior. Although Acanthomorpha was recognized decades ago, we are only now beginning to decipher its large-scale, time-calibrated phylogeny, a prerequisite to test various evolutionary hypotheses explaining the tremendous diversity of this group. In this study, we provide new insights into the early evolution of the acanthomorphs and the euteleost allies based on the phylogenetic analysis of a newly developed dataset combining nine nuclear and mitochondrial gene markers. Our inferred tree is time-calibrated using 15 fossils, some of which have not been used before. While our phylogeny strongly supports a monophyletic Neoteleostei, Ctenosquamata (i.e., Acanthomorpha plus Myctophiformes, and Acanthopterygii, we find weak support (bootstrap value < 48% for the traditionally defined Acanthomorpha, as well as evidence of non-monophyly for the traditional Paracanthopterygii, Beryciformes, and Percomorpha. We corroborate the new Paracanthopterygii sensu Miya et al. (2005 including Polymixiiformes, Zeiformes, Gadiformes, Percopsiformes, and likely the enigmatic Stylephorus chordatus. Our timetree largely agrees with other recent studies based on nuclear loci in inferring an Early Cretaceous origin for the acanthomorphs followed by a Late Cretaceous/Early Paleogene radiation of major lineages. This is in contrast to mitogenomic studies mostly inferring Jurassic or even Triassic ages for the origin of the acanthomorphs. We compare our results to those of previous studies, and attempt to address some of the issues that may have led to incongruence between the fossil record and the molecular clock studies, as well as between the different molecular

Insights into the Evolution of Hydroxyproline-Rich Glycoproteins from 1000 Plant Transcriptomes1[OPEN

Science.gov (United States)

Cassin, Andrew M.; Soltis, Douglas E.; Miles, Nicholas W.; Melkonian, Michael; Melkonian, Barbara; Wu, Shuangxiu; Edger, Patrick P.; Carpenter, Eric J.

2017-01-01

The carbohydrate-rich cell walls of land plants and algae have been the focus of much interest given the value of cell wall-based products to our current and future economies. Hydroxyproline-rich glycoproteins (HRGPs), a major group of wall glycoproteins, play important roles in plant growth and development, yet little is known about how they have evolved in parallel with the polysaccharide components of walls. We investigate the origins and evolution of the HRGP superfamily, which is commonly divided into three major multigene families: the arabinogalactan proteins (AGPs), extensins (EXTs), and proline-rich proteins. Using motif and amino acid bias, a newly developed bioinformatics pipeline, we identified HRGPs in sequences from the 1000 Plants transcriptome project (www.onekp.com). Our analyses provide new insights into the evolution of HRGPs across major evolutionary milestones, including the transition to land and the early radiation of angiosperms. Significantly, data mining reveals the origin of glycosylphosphatidylinositol (GPI)-anchored AGPs in green algae and a 3- to 4-fold increase in GPI-AGPs in liverworts and mosses. The first detection of cross-linking (CL)-EXTs is observed in bryophytes, which suggests that CL-EXTs arose though the juxtaposition of preexisting SPn EXT glycomotifs with refined Y-based motifs. We also detected the loss of CL-EXT in a few lineages, including the grass family (Poaceae), that have a cell wall composition distinct from other monocots and eudicots. A key challenge in HRGP research is tracking individual HRGPs throughout evolution. Using the 1000 Plants output, we were able to find putative orthologs of Arabidopsis pollen-specific GPI-AGPs in basal eudicots. PMID:28446636

The Corporate University's Role in Managing an Epoch in Learning Organisation Innovation

Science.gov (United States)

Dealtry, Richard

2006-01-01

Purpose: The purpose of this paper is to set the scene for some radical epochal thinking about the approach and future strategic directions in the management of organisational learning, following the author's earlier editorial theme concerning the need for exploration and innovation in organisational learning management.…

The zCOSMOS redshift survey : evolution of the light in bulges and discs since z ~ 0.8

NARCIS (Netherlands)

Tasca, L. A. M.; Tresse, L.; Le Fevre, O.; Ilbert, O.; Lilly, S. J.; Zamorani, G.; Lopez-Sanjuan, C.; Ho, L. C.; Bardelli, S.; Cattaneo, A.; Cucciati, O.; Farrah, D.; Iovino, A.; Koekemoer, A. M.; Liu, C. T.; Massey, R.; Renzini, A.; Taniguchi, Y.; Welikala, N.; Zucca, E.; Carollo, C. M.; Contini, T.; Kneib, J. -P.; Mainieri, V.; Scodeggio, M.; Bolzonella, M.; Bongiorno, A.; Caputi, K.; de la Torre, S.; Franzetti, P.; Garilli, B.; Guzzo, L.; Kampczyk, P.; Knobel, C.; Kovac, K.; Lamareille, F.; Le Borgne, J. -F.; Le Brun, V.; Maier, C.; Mignoli, M.; Pello, R.; Peng, Y.; Perez Montero, E.; Rich, R. M.; Tanaka, M.; Vergani, D.; Bordoloi, R.; Cappi, A.; Cimatti, A.; Coppa, G.; McCracken, H. J.; Moresco, M.; Pozzetti, L.; Sanders, D.; Sheth, K.

We studied the chronology of galactic bulge and disc formation by analysing the relative contributions of these components to the B-band rest-frame luminosity density at different epochs. We present the first estimate of the evolution of the fraction of rest-frame B-band light in galactic bulges and

The zCOSMOS redshift survey: evolution of the light in bulges and discs since z ~ 0.8

NARCIS (Netherlands)

Tasca, L. A. M.; Tresse, L.; Le Fèvre, O.; Ilbert, O.; Lilly, S. J.; Zamorani, G.; López-Sanjuan, C.; Ho, L. C.; Bardelli, S.; Cattaneo, A.; Cucciati, O.; Farrah, D.; Iovino, A.; Koekemoer, A. M.; Liu, C. T.; Massey, R.; Renzini, A.; Taniguchi, Y.; Welikala, N.; Zucca, E.; Carollo, C. M.; Contini, T.; Kneib, J.-P.; Mainieri, V.; Scodeggio, M.; Bolzonella, M.; Bongiorno, A.; Caputi, K.; de la Torre, S.; Franzetti, P.; Garilli, B.; Guzzo, L.; Kampczyk, P.; Knobel, C.; Kovač, K.; Lamareille, F.; Le Borgne, J.-F.; Le Brun, V.; Maier, C.; Mignoli, M.; Pello, R.; Peng, Y.; Perez Montero, E.; Rich, R. M.; Tanaka, M.; Vergani, D.; Bordoloi, R.; Cappi, A.; Cimatti, A.; Coppa, G.; McCracken, H. J.; Moresco, M.; Pozzetti, L.; Sanders, D.; Sheth, K.

We studied the chronology of galactic bulge and disc formation by analysing the relative contributions of these components to the B-band rest-frame luminosity density at different epochs. We present the first estimate of the evolution of the fraction of rest-frame B-band light in galactic bulges and

The Square Kilometre Array Epoch of Reionisation and Cosmic Dawn Experiment

Science.gov (United States)

Trott, Cathryn M.

2018-05-01

The Square Kilometre Array (SKA) Epoch of Reionisation and Cosmic Dawn (EoR/CD) experiments aim to explore the growth of structure and production of ionising radiation in the first billion years of the Universe. Here I describe the experiments planned for the future low-frequency components of the Observatory, and work underway to define, design and execute these programs.

EVOLUTION OF THE WATER MASER EXPANDING SHELL IN W75N VLA 2

Energy Technology Data Exchange (ETDEWEB)

Kim, Jeong-Sook; Kim, Sang Joon [School of Space Science, Kyunghee University, Seocheon-dong, Giheung-si, Gyeonggi-do, 446-701 (Korea, Republic of); Kim, Soon-Wook [Korea Astronomy and Space Science Institute, 776 Daedeokdaero, Yuseong, Daejeon 305-348 (Korea, Republic of); Kurayama, Tomoharu [Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima, Kagoshima 890-0065 (Japan); Honma, Mareki [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Sasao, Tesuo [Yaeyama Star Club, Ookawa, Ishigaki, Okinawa 904-0022 (Japan); Surcis, Gabriele [Joint Institute for VLBI in Europe, Postbus 2, 7990 AA Dwingeloo (Netherlands); Canto, Jorge [Instituto de Astronomia (UNAM), Apartado 70-264, 04510 Mexico D. F. (Mexico); Torrelles, Jose M., E-mail: evony@kasi.re.kr, E-mail: skim@kasi.re.kr [Instituto de Ciencias del Espacio (CSIC)-UB/IEEC, Universitat de Barcelona, Marti i Franques 1, E-08028 Barcelona (Spain)

2013-04-10

We present Very Long Baseline Interferometry (VLBI) observations of 22 GHz H{sub 2}O masers in the high-mass star-forming region of W75N, carried out with VLBI Exploration of Radio Astrometry (VERA) for three epochs in 2007 with an angular resolution of {approx}1 mas. We detected H{sub 2}O maser emission toward the radio jet in VLA 1 and the expanding shell-like structure in VLA 2. The spatial distribution of the H{sub 2}O masers detected with VERA and measured proper motions around VLA 1 and VLA 2 are similar to those found with previous VLBI observations in epochs 1999 and 2005, with the masers in VLA 1 mainly distributed along a linear structure parallel to the radio jet and, on the other hand, forming a shell-like structure around VLA 2. We have made elliptical fits to the VLA 2 H{sub 2}O maser shell-like structure observed in the different epochs (1999, 2005, and 2007), and found that the shell is still expanding eight years after its discovery. From the difference in the size of the semi-major axes of the fitted ellipses in epochs 1999 ({approx_equal}71 {+-} 1 mas), 2005 ({approx_equal}97 {+-} 3 mas), and 2007 ({approx_equal}111 {+-} 1 mas), we estimate an average expanding velocity of {approx}5 mas yr{sup -1}, similar to the proper motions measured in the individual H{sub 2}O maser features. A kinematic age of {approx}20 yr is derived for this structure. In addition, our VERA observations indicate an increase in the ellipticity of the expanding shell around VLA 2 from epochs 1999 to 2007. In fact, the elliptical fit of the VERA data shows a ratio of the minor and major axes of {approx}0.6, in contrast with an almost circular shape for the shell detected in 1999 and 2005 (b/a {approx} 0.9). This suggests that we are probably observing the formation of a jet-driven H{sub 2}O maser structure in VLA2, evolving from a non-collimated pulsed-outflow event during the first stages of evolution of a massive young stellar object (YSO). This may support predictions made

Seeking the epoch of maximum luminosity for dusty quasars

International Nuclear Information System (INIS)

Vardanyan, Valeri; Weedman, Daniel; Sargsyan, Lusine

2014-01-01

Infrared luminosities νL ν (7.8 μm) arising from dust reradiation are determined for Sloan Digital Sky Survey (SDSS) quasars with 1.4 10 46.6 erg s –1 for all 2 epoch when quasars first reached their maximum luminosity has not yet been identified at any redshift below 5. The most ultraviolet luminous quasars, defined by rest frame νL ν (0.25 μm), have the largest values of the ratio νL ν (0.25 μm)/νL ν (7.8 μm) with a maximum ratio at z = 2.9. From these results, we conclude that the quasars most luminous in the ultraviolet have the smallest dust content and appear luminous primarily because of lessened extinction. Observed ultraviolet/infrared luminosity ratios are used to define 'obscured' quasars as those having >5 mag of ultraviolet extinction. We present a new summary of obscured quasars discovered with the Spitzer Infrared Spectrograph and determine the infrared luminosity function of these obscured quasars at z ∼ 2.1. This is compared with infrared luminosity functions of optically discovered, unobscured quasars in the SDSS and in the AGN and Galaxy Evolution Survey. The comparison indicates comparable numbers of obscured and unobscured quasars at z ∼ 2.1 with a possible excess of obscured quasars at fainter luminosities.

Geometrothermodynamic model for the evolution of the Universe

Energy Technology Data Exchange (ETDEWEB)

Gruber, Christine; Quevedo, Hernando, E-mail: christine.gruber@correo.nucleares.unam.mx, E-mail: quevedo@nucleares.unam.mx [Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, AP 70543, México, DF 04510 (Mexico)

2017-07-01

Using the formalism of geometrothermodynamics to derive a fundamental thermodynamic equation, we construct a cosmological model in the framework of relativistic cosmology. In a first step, we describe a system without thermodynamic interaction, and show it to be equivalent to the standard ΛCDM paradigm. The second step includes thermodynamic interaction and produces a model consistent with the main features of inflation. With the proposed fundamental equation we are thus able to describe all the known epochs in the evolution of our Universe, starting from the inflationary phase.

The transcriptome of Nacobbus aberrans reveals insights into the evolution of sedentary endoparasitism in plant-parasitic nematodes.

Science.gov (United States)

Eves-van den Akker, Sebastian; Lilley, Catherine J; Danchin, Etienne G J; Rancurel, Corinne; Cock, Peter J A; Urwin, Peter E; Jones, John T

2014-08-13

Within the phylum Nematoda, plant-parasitism is hypothesized to have arisen independently on at least four occasions. The most economically damaging plant-parasitic nematode species, and consequently the most widely studied, are those that feed as they migrate destructively through host roots causing necrotic lesions (migratory endoparasites) and those that modify host root tissue to create a nutrient sink from which they feed (sedentary endoparasites). The false root-knot nematode Nacobbus aberrans is the only known species to have both migratory endoparasitic and sedentary endoparasitic stages within its life cycle. Moreover, its sedentary stage appears to have characteristics of both the root-knot and the cyst nematodes. We present the first large-scale genetic resource of any false-root knot nematode species. We use RNAseq to describe relative abundance changes in all expressed genes across the life cycle to provide interesting insights into the biology of this nematode as it transitions between modes of parasitism. A multigene phylogenetic analysis of N. aberrans with respect to plant-parasitic nematodes of all groups confirms its proximity to both cyst and root-knot nematodes. We present a transcriptome-wide analysis of both lateral gene transfer events and the effector complement. Comparing parasitism genes of typical root-knot and cyst nematodes to those of N. aberrans has revealed interesting similarities. Importantly, genes that were believed to be either cyst nematode, or root-knot nematode, "specific" have both been identified in N. aberrans. Our results provide insights into the characteristics of a common ancestor and the evolution of sedentary endoparasitism of plants by nematodes. © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Archeological insights into hominin cognitive evolution.

Science.gov (United States)

Wynn, Thomas; Coolidge, Frederick L

2016-07-01

How did the human mind evolve? How and when did we come to think in the ways we do? The last thirty years have seen an explosion in research related to the brain and cognition. This research has encompassed a range of biological and social sciences, from epigenetics and cognitive neuroscience to social and developmental psychology. Following naturally on this efflorescence has been a heightened interest in the evolution of the brain and cognition. Evolutionary scholars, including paleoanthropologists, have deployed the standard array of evolutionary methods. Ethological and experimental evidence has added significantly to our understanding of nonhuman brains and cognition, especially those of nonhuman primates. Studies of fossil brains through endocasts and sophisticated imaging techniques have revealed evolutionary changes in gross neural anatomy. Psychologists have also gotten into the game through application of reverse engineering to experimentally based descriptions of cognitive functions. For hominin evolution, there is another rich source of evidence of cognition, the archeological record. Using the methods of Paleolithic archeology and the theories and models of cognitive science, evolutionary cognitive archeology documents developments in the hominin mind that would otherwise be inaccessible. © 2016 Wiley Periodicals, Inc.

Signals from the epoch of cosmological recombination (Karl Schwarzschild Award Lecture 2008)

Science.gov (United States)

Sunyaev, R. A.; Chluba, J.

2009-07-01

The physical ingredients to describe the epoch of cosmological recombination are amazingly simple and well-understood. This fact allows us to take into account a very large variety of physical processes, still finding potentially measurable consequences for the energy spectrum and temperature anisotropies of the Cosmic Microwave Background (CMB). In this contribution we provide a short historical overview in connection with the cosmological recombination epoch and its connection to the CMB. Also we highlight some of the detailed physics that were studied over the past few years in the context of the cosmological recombination of hydrogen and helium. The impact of these considerations is two-fold: The associated release of photons during this epoch leads to interesting and unique deviations of the Cosmic Microwave Background (CMB) energy spectrum from a perfect blackbody, which, in particular at decimeter wavelength and the Wien part of the CMB spectrum, may become observable in the near future. Despite the fact that the abundance of helium is rather small, it still contributes a sizeable amount of photons to the full recombination spectrum, leading to additional distinct spectral features. Observing the spectral distortions from the epochs of hydrogen and helium recombination, in principle would provide an additional way to determine some of the key parameters of the Universe (e.g. the specific entropy, the CMB monopole temperature and the pre-stellar abundance of helium). Also it permits us to confront our detailed understanding of the recombination process with direct observational evidence. In this contribution we illustrate how the theoretical spectral template of the cosmological recombination spectrum may be utilized for this purpose. We also show that because hydrogen and helium recombine at very different epochs it is possible to address questions related to the thermal history of our Universe. In particular the cosmological recombination radiation may

Eggshell Porosity Provides Insight on Evolution of Nesting in Dinosaurs.

Directory of Open Access Journals (Sweden)

Kohei Tanaka

Full Text Available Knowledge about the types of nests built by dinosaurs can provide insight into the evolution of nesting and reproductive behaviors among archosaurs. However, the low preservation potential of their nesting materials and nesting structures means that most information can only be gleaned indirectly through comparison with extant archosaurs. Two general nest types are recognized among living archosaurs: 1 covered nests, in which eggs are incubated while fully covered by nesting material (as in crocodylians and megapodes, and 2 open nests, in which eggs are exposed in the nest and brooded (as in most birds. Previously, dinosaur nest types had been inferred by estimating the water vapor conductance (i.e., diffusive capacity of their eggs, based on the premise that high conductance corresponds to covered nests and low conductance to open nests. However, a lack of statistical rigor and inconsistencies in this method render its application problematic and its validity questionable. As an alternative we propose a statistically rigorous approach to infer nest type based on large datasets of eggshell porosity and egg mass compiled for over 120 extant archosaur species and 29 archosaur extinct taxa/ootaxa. The presence of a strong correlation between eggshell porosity and nest type among extant archosaurs indicates that eggshell porosity can be used as a proxy for nest type, and thus discriminant analyses can help predict nest type in extinct taxa. Our results suggest that: 1 covered nests are likely the primitive condition for dinosaurs (and probably archosaurs, and 2 open nests first evolved among non-avian theropods more derived than Lourinhanosaurus and were likely widespread in non-avian maniraptorans, well before the appearance of birds. Although taphonomic evidence suggests that basal open nesters (i.e., oviraptorosaurs and troodontids were potentially the first dinosaurs to brood their clutches, they still partially buried their eggs in sediment

Eggshell Porosity Provides Insight on Evolution of Nesting in Dinosaurs.

Science.gov (United States)

Tanaka, Kohei; Zelenitsky, Darla K; Therrien, François

2015-01-01

Knowledge about the types of nests built by dinosaurs can provide insight into the evolution of nesting and reproductive behaviors among archosaurs. However, the low preservation potential of their nesting materials and nesting structures means that most information can only be gleaned indirectly through comparison with extant archosaurs. Two general nest types are recognized among living archosaurs: 1) covered nests, in which eggs are incubated while fully covered by nesting material (as in crocodylians and megapodes), and 2) open nests, in which eggs are exposed in the nest and brooded (as in most birds). Previously, dinosaur nest types had been inferred by estimating the water vapor conductance (i.e., diffusive capacity) of their eggs, based on the premise that high conductance corresponds to covered nests and low conductance to open nests. However, a lack of statistical rigor and inconsistencies in this method render its application problematic and its validity questionable. As an alternative we propose a statistically rigorous approach to infer nest type based on large datasets of eggshell porosity and egg mass compiled for over 120 extant archosaur species and 29 archosaur extinct taxa/ootaxa. The presence of a strong correlation between eggshell porosity and nest type among extant archosaurs indicates that eggshell porosity can be used as a proxy for nest type, and thus discriminant analyses can help predict nest type in extinct taxa. Our results suggest that: 1) covered nests are likely the primitive condition for dinosaurs (and probably archosaurs), and 2) open nests first evolved among non-avian theropods more derived than Lourinhanosaurus and were likely widespread in non-avian maniraptorans, well before the appearance of birds. Although taphonomic evidence suggests that basal open nesters (i.e., oviraptorosaurs and troodontids) were potentially the first dinosaurs to brood their clutches, they still partially buried their eggs in sediment. Open nests

Polarization leakage in epoch of reionization windows : The Low Frequency Array Case

NARCIS (Netherlands)

Asad, Khan

2017-01-01

The farther we look in space, the earlier we see in time. By observing a radio signal of 21cm wavelength coming from the epoch of reionization, when the universe was less than a billion years old, we can understand how the first stars, galaxies and black holes formed. This signal has not been

Root evolution at the base of the lycophyte clade: insights from an Early Devonian lycophyte

Science.gov (United States)

Matsunaga, Kelly K. S.; Tomescu, Alexandru M. F.

2016-01-01

Background and Aims The evolution of complex rooting systems during the Devonian had significant impacts on global terrestrial ecosystems and the evolution of plant body plans. However, detailed understanding of the pathways of root evolution and the architecture of early rooting systems is currently lacking. We describe the architecture and resolve the structural homology of the rooting system of an Early Devonian basal lycophyte. Insights gained from these fossils are used to address lycophyte root evolution and homology. Methods Plant fossils are preserved as carbonaceous compressions at Cottonwood Canyon (Wyoming), in the Lochkovian–Pragian (∼411 Ma; Early Devonian) Beartooth Butte Formation. We analysed 177 rock specimens and documented morphology, cuticular anatomy and structural relationships, as well as stratigraphic position and taphonomic conditions. Key Results The rooting system of the Cottonwood Canyon lycophyte is composed of modified stems that bear fine, dichotomously branching lateral roots. These modified stems, referred to as root-bearing axes, are produced at branching points of the above-ground shoot system. Root-bearing axes preserved in growth position exhibit evidence of positive gravitropism, whereas the lateral roots extend horizontally. Consistent recurrence of these features in successive populations of the plant preserved in situ demonstrates that they represent constitutive structural traits and not opportunistic responses of a flexible developmental programme. Conclusions This is the oldest direct evidence for a rooting system preserved in growth position. These rooting systems, which can be traced to a parent plant, include some of the earliest roots known to date and demonstrate that substantial plant–substrate interactions were under way by Early Devonian time. The morphological relationships between stems, root-bearing axes and roots corroborate evidence that positive gravitropism and root identity were evolutionarily

Insights on fluid-rock interaction evolution during deformation from fracture network geochemistry at reservoir-scale

Science.gov (United States)

Beaudoin, Nicolas; Koehn, Daniel; Lacombe, Olivier; Bellahsen, Nicolas; Emmanuel, Laurent

2015-04-01

Fluid migration and fluid-rock interactions during deformation is a challenging problematic to picture. Numerous interplays, as between porosity-permeability creation and clogging, or evolution of the mechanical properties of rock, are key features when it comes to monitor reservoir evolution, or to better understand seismic cycle n the shallow crust. These phenomenoms are especially important in foreland basins, where various fluids can invade strata and efficiently react with limestones, altering their physical properties. Stable isotopes (O, C, Sr) measurements and fluid inclusion microthermometry of faults cement and veins cement lead to efficient reconstruction of the origin, temperature and migration pathways for fluids (i.e. fluid system) that precipitated during joints opening or faults activation. Such a toolbox can be used on a diffuse fracture network that testifies the local and/or regional deformation history experienced by the rock at reservoir-scale. This contribution underlines the advantages and limits of geochemical studies of diffuse fracture network at reservoir-scale by presenting results of fluid system reconstruction during deformation in folded structures from various thrust-belts, tectonic context and deformation history. We compare reconstructions of fluid-rock interaction evolution during post-deposition, post-burial growth of basement-involved folds in the Sevier-Laramide American Rocky Mountains foreland, a reconstruction of fluid-rock interaction evolution during syn-depostion shallow detachment folding in the Southern Pyrenean foreland, and a preliminary reconstruction of fluid-rock interactions in a post-deposition, post-burial development of a detachment fold in the Appenines. Beyond regional specification for the nature of fluids, a common behavior appears during deformation as in every fold, curvature-related joints (related either to folding or to foreland flexure) connected vertically the pre-existing stratified fluid system

Detectability of the 21-cm CMB cross-correlation from the epoch of reionization

NARCIS (Netherlands)

Tashiro, Hiroyuki; Aghanim, Nabila; Langer, Mathieu; Douspis, Marian; Zaroubi, Saleem; Jelic, Vibor

The 21-cm line fluctuations and the cosmic microwave background (CMB) are powerful probes of the epoch of reionization of the Universe. We study the potential of the cross-correlation between 21-cm line fluctuations and CMB anisotropy to obtain further constraints on the reionization history. We

Experimental evolution in biofilm populations

Science.gov (United States)

Steenackers, Hans P.; Parijs, Ilse; Foster, Kevin R.; Vanderleyden, Jozef

2016-01-01

Biofilms are a major form of microbial life in which cells form dense surface associated communities that can persist for many generations. The long-life of biofilm communities means that they can be strongly shaped by evolutionary processes. Here, we review the experimental study of evolution in biofilm communities. We first provide an overview of the different experimental models used to study biofilm evolution and their associated advantages and disadvantages. We then illustrate the vast amount of diversification observed during biofilm evolution, and we discuss (i) potential ecological and evolutionary processes behind the observed diversification, (ii) recent insights into the genetics of adaptive diversification, (iii) the striking degree of parallelism between evolution experiments and real-life biofilms and (iv) potential consequences of diversification. In the second part, we discuss the insights provided by evolution experiments in how biofilm growth and structure can promote cooperative phenotypes. Overall, our analysis points to an important role of biofilm diversification and cooperation in bacterial survival and productivity. Deeper understanding of both processes is of key importance to design improved antimicrobial strategies and diagnostic techniques. PMID:26895713

Multi-epoch analysis of the X-ray spectrum of the active galactic nucleus in NGC 5506

Science.gov (United States)

Sun, Shangyu; Guainazzi, Matteo; Ni, Qingling; Wang, Jingchun; Qian, Chenyang; Shi, Fangzheng; Wang, Yu; Bambi, Cosimo

2018-05-01

We present a multi-epoch X-ray spectroscopy analysis of the nearby narrow-line Seyfert I galaxy NGC 5506. For the first time, spectra taken by Chandra, XMM-Newton, Suzaku, and NuSTAR - covering the 2000-2014 time span - are analyzed simultaneously, using state-of-the-art models to describe reprocessing of the primary continuum by optical thick matter in the AGN environment. The main goal of our study is determining the spin of the supermassive black hole (SMBH). The nuclear X-ray spectrum is photoelectrically absorbed by matter with column density ≃ 3 × 1022 cm-2. A soft excess is present at energies lower than the photoelectric cut-off. Both photo-ionized and collisionally ionized components are required to fit it. This component is constant over the time-scales probed by our data. The spectrum at energies higher than 2 keV is variable. We propose that its evolution could be driven by flux-dependent changes in the geometry of the innermost regions of the accretion disk. The black hole spin in NGC ,5506 is constrained to be 0.93± _{ 0.04 }^{0.04} at 90% confidence level for one interesting parameter.

Coordinating supplier-retailer using multiple common replenishment epochs with retailers’ choices

Directory of Open Access Journals (Sweden)

Juhwen Hwang

2013-06-01

Full Text Available Purpose: Provide a coordination strategy using multiple common replenishment epochs (MCRE for a single-supplier multi-retailer supply chain. Design/methodology/approach: The demand of a product occurs only with a group of heterogeneous and independent retailers with constant rates, whereas all their order requests are fulfilled by the supplier. The supplier decides a set of MCREs with general price and extra bonus to entice the retailers to join any one of the MCREs, or to let them remain with their original order time epochs. A retailer is willing to participate in a CRE as long as the retailer’s cost increase is within its tolerance. This paper provide a mixed integer programming to determine the MCRE strategies in order to minimize the total costs of the supplier. Findings: The results illustrate that MCRE model provided in the paper can generate a better replenishment coordination scheme than single CRE models. Practical implications: Replenishment coordination is one of the most important mechanisms to improve the efficiency in supply chains, e.g., chain convenience stores in the modern retail industry. Originality/value: This is a follow-up research on Joint Economic Lot Size (JELS models with a focus on multiple retailers with their replenishment coordination.

Comparative Riftology: Insights into the Evolution of Passive Continental Margins and Continental Rifts from the Failed Midcontinent Rift (MCR)

Science.gov (United States)

Elling, R. P.; Stein, C. A.; Stein, S.; Kley, J.; Keller, G. R.; Wysession, M. E.

2017-12-01

Continental rifts evolve to seafloor spreading and are preserved in passive margins, or fail and remain as fossil features in continents. Rifts at different stages give insight into these evolutionary paths. Of particular interest is the evolution of volcanic passive margins, which are characterized by seaward dipping reflectors, volcanic rocks yielding magnetic anomalies landward of the oldest spreading anomalies, and are underlain by high-velocity lower crustal bodies. How and when these features form remains unclear. Insights are given by the Midcontinent Rift (MCR), which began to form during the 1.1 Ga rifting of Amazonia from Laurentia, but failed when seafloor spreading was established elsewhere. MCR volcanics are much thicker than other continental flood basalts, due to deposition in a narrow rift rather than a broad region, giving a rift's geometry but a LIP's magma volume. The MCR provides a snapshot of the deposition of a thick and highly magnetized volcanic section during rifting. Surface exposures and reflection seismic data near Lake Superior show a rift basin filled by inward-dipping flood basalt layers. Had the rift evolved to seafloor spreading, the basin would have split into two sets of volcanics with opposite-facing SDRs, each with a magnetic anomaly. Because the rift formed as a series of alternating half-grabens, structural asymmetries between conjugate margins would have naturally occurred had it gone to completion. Hence the MCR implies that many passive margin features form prior to seafloor spreading. Massive inversion of the MCR long after it failed has provided a much clearer picture of its structure compared to failed rifts with lesser degrees of inversion. Seismic imaging as well as gravity and magnetic modeling provide important insight into the effects of inversion on failed rifts. The MCR provides an end member for the evolution of actively extending rifts, characterized by upwelling mantle and negative gravity anomalies, to failed

Evolution of the vertebrate claudin gene family: insights from a basal vertebrate, the sea lamprey.

Science.gov (United States)

Mukendi, Christian; Dean, Nicholas; Lala, Rushil; Smith, Jeramiah; Bronner, Marianne E; Nikitina, Natalya V

2016-01-01

Claudins are major constituents of tight junctions, contributing both to their intercellular sealing and selective permeability properties. While claudins and claudin-like molecules are present in some invertebrates, the association of claudins with tight junctions has been conclusively documented only in vertebrates. Here we report the sequencing, phylogenetic analysis and comprehensive spatiotemporal expression analysis of the entire claudin gene family in the basal extant vertebrate, the sea lamprey. Our results demonstrate that clear orthologues to about half of all mammalian claudins are present in the lamprey, suggesting that at least one round of whole genome duplication contributed to the diversification of this gene family. Expression analysis revealed that claudins are expressed in discrete and specific domains, many of which represent vertebrate-specific innovations, such as in cranial ectodermal placodes and the neural crest; whereas others represent structures characteristic of chordates, e.g. pronephros, notochord, somites, endostyle and pharyngeal arches. By comparing the embryonic expression of claudins in the lamprey to that of other vertebrates, we found that ancestral expression patterns were often preserved in higher vertebrates. Morpholino mediated loss of Cldn3b demonstrated a functional role for this protein in placode and pharyngeal arch morphogenesis. Taken together, our data provide novel insights into the origins and evolution of the claudin gene family and the significance of claudin proteins in the evolution of vertebrates.

Importance of epoch length and registration time on accelerometer measurements in younger children

DEFF Research Database (Denmark)

Dencker, M; Svensson, J; El-Naaman, B

2012-01-01

The aim of this study was to investigate the effect of epoch length on accumulation of minutes of physical activity per day over a spectrum of intensities, and the effect that selection of number of hours of acceptable registration required per day had on number of days that were considered accep...

Evolution of the TOR Pathway.

NARCIS (Netherlands)

Dam, T.J.P. van; Zwartkruis, F.J.; Bos, J.L.; Snel, B.

2011-01-01

The TOR kinase is a major regulator of growth in eukaryotes. Many components of the TOR pathway are implicated in cancer and metabolic diseases in humans. Analysis of the evolution of TOR and its pathway may provide fundamental insight into the evolution of growth regulation in eukaryotes and

Plasmids and rickettsial evolution: insight from Rickettsia felis.

Directory of Open Access Journals (Sweden)

Joseph J Gillespie

2007-03-01

Full Text Available The genome sequence of Rickettsia felis revealed a number of rickettsial genetic anomalies that likely contribute not only to a large genome size relative to other rickettsiae, but also to phenotypic oddities that have confounded the categorization of R. felis as either typhus group (TG or spotted fever group (SFG rickettsiae. Most intriguing was the first report from rickettsiae of a conjugative plasmid (pRF that contains 68 putative open reading frames, several of which are predicted to encode proteins with high similarity to conjugative machinery in other plasmid-containing bacteria.Using phylogeny estimation, we determined the mode of inheritance of pRF genes relative to conserved rickettsial chromosomal genes. Phylogenies of chromosomal genes were in agreement with other published rickettsial trees. However, phylogenies including pRF genes yielded different topologies and suggest a close relationship between pRF and ancestral group (AG rickettsiae, including the recently completed genome of R. bellii str. RML369-C. This relatedness is further supported by the distribution of pRF genes across other rickettsiae, as 10 pRF genes (or inactive derivatives also occur in AG (but not SFG rickettsiae, with five of these genes characteristic of typical plasmids. Detailed characterization of pRF genes resulted in two novel findings: the identification of oriV and replication termination regions, and the likelihood that a second proposed plasmid, pRFdelta, is an artifact of the original genome assembly.Altogether, we propose a new rickettsial classification scheme with the addition of a fourth lineage, transitional group (TRG rickettsiae, that is unique from TG and SFG rickettsiae and harbors genes from possible exchanges with AG rickettsiae via conjugation. We offer insight into the evolution of a plastic plasmid system in rickettsiae, including the role plasmids may have played in the acquirement of virulence traits in pathogenic strains, and the

Spectral evolution of galaxies

International Nuclear Information System (INIS)

Rocca-Volmerange, B.

1989-01-01

A recent striking event in Observational Cosmology is the discovery of a large population of galaxies at extreme cosmological distances (extended from spectral redshifts ≅ 1 to ≥ 3) corresponding to a lookback time of 80% of the Universe's age. However when galaxies are observed at such remote epochs, their appearances are affected by at least two simultaneous effects which are respectively a cosmological effect and the intrinsic evolution of their stellar populations which appear younger than in our nearby galaxies. The fundamental problem is first to disentangle the respective contributions of these two effects to apparent magnitudes and colors of distant galaxies. Other effects which are likely to modify the appearance of galaxies are amplification by gravitational lensing and interaction with environment will also be considered. (author)

Evolution in linear sizes and the Faraday effects in radio sources

International Nuclear Information System (INIS)

Anene, G.; Ugwoke, A.C.

2001-05-01

It is still a matter of conjecture whether the observed depolarization in radio sources originate from an external Faraday screen lying in our line of sight, or is largely due to internal processes occurring within these sources. This paper argues for an external origin. By applying recent evidences from the evolution of linear sizes while allowing for selection effects, it is shown that the density parameters within radio sources do not depend on redshift, implying that the observed depolarizations is epoch independent and may therefore, be largely external in origin. We also show that the observed low correlation between λ 1/2 and linear size(D) cannot be improved much even when allowance is made for evolution in D. (author)

Insights into hominid evolution from the gorilla genome sequence

Science.gov (United States)

Scally, Aylwyn; Dutheil, Julien Y.; Hillier, LaDeana W.; Jordan, Greg E.; Goodhead, Ian; Herrero, Javier; Hobolth, Asger; Lappalainen, Tuuli; Mailund, Thomas; Marques-Bonet, Tomas; McCarthy, Shane; Montgomery, Stephen H.; Schwalie, Petra C.; Tang, Y. Amy; Ward, Michelle C.; Xue, Yali; Yngvadottir, Bryndis; Alkan, Can; Andersen, Lars N.; Ayub, Qasim; Ball, Edward V.; Beal, Kathryn; Bradley, Brenda J.; Chen, Yuan; Clee, Chris M.; Fitzgerald, Stephen; Graves, Tina A.; Gu, Yong; Heath, Paul; Heger, Andreas; Karakoc, Emre; Kolb-Kokocinski, Anja; Laird, Gavin K.; Lunter, Gerton; Meader, Stephen; Mort, Matthew; Mullikin, James C.; Munch, Kasper; O’Connor, Timothy D.; Phillips, Andrew D.; Prado-Martinez, Javier; Rogers, Anthony S.; Sajjadian, Saba; Schmidt, Dominic; Shaw, Katy; Simpson, Jared T.; Stenson, Peter D.; Turner, Daniel J.; Vigilant, Linda; Vilella, Albert J.; Whitener, Weldon; Zhu, Baoli; Cooper, David N.; de Jong, Pieter; Dermitzakis, Emmanouil T.; Eichler, Evan E.; Flicek, Paul; Goldman, Nick; Mundy, Nicholas I.; Ning, Zemin; Odom, Duncan T.; Ponting, Chris P.; Quail, Michael A.; Ryder, Oliver A.; Searle, Stephen M.; Warren, Wesley C.; Wilson, Richard K.; Schierup, Mikkel H.; Rogers, Jane; Tyler-Smith, Chris; Durbin, Richard

2012-01-01

Summary Gorillas are humans’ closest living relatives after chimpanzees, and are of comparable importance for the study of human origins and evolution. Here we present the assembly and analysis of a genome sequence for the western lowland gorilla, and compare the whole genomes of all extant great ape genera. We propose a synthesis of genetic and fossil evidence consistent with placing the human-chimpanzee and human-chimpanzee-gorilla speciation events at approximately 6 and 10 million years ago (Mya). In 30% of the genome, gorilla is closer to human or chimpanzee than the latter are to each other; this is rarer around coding genes, indicating pervasive selection throughout great ape evolution, and has functional consequences in gene expression. A comparison of protein coding genes reveals approximately 500 genes showing accelerated evolution on each of the gorilla, human and chimpanzee lineages, and evidence for parallel acceleration, particularly of genes involved in hearing. We also compare the western and eastern gorilla species, estimating an average sequence divergence time 1.75 million years ago, but with evidence for more recent genetic exchange and a population bottleneck in the eastern species. The use of the genome sequence in these and future analyses will promote a deeper understanding of great ape biology and evolution. PMID:22398555

Spectrum evolution of primordial cosmic turbulence

International Nuclear Information System (INIS)

Futamase, T.; Matsuda, T.

1980-01-01

The evolution of primordial cosmic turbulence prior to the epoch of plasma recombination is investigated numerically using the Wiener-Hermite expansion technique which gives reasonable results for laboratory turbulence. It is found that the Kolmogorov spectrum is established only within a narrow range of wavenumber space for reasonable parameter sets, because the expansion of the Universe has a tendency to suppress an energy cascade from larger eddies to smaller ones. The present result does not agree with that obtained by Kurskov and Ozernoi, who computed the decay of turbulence in a fictitious non-expanding frame using the Heisenberg closure hypothesis, while it was done in a physical frame in the present work. (author)

Co-evolution of elliptical galaxies and their central black holes

International Nuclear Information System (INIS)

Ciotti, I.

2009-01-01

After the discovery that supermassive black holes (SMBHs) are ubiquitous at the center of stellar spheroids and that their mass M BH , in the range 10 6 M-10 9 M, is tightly related to global properties of the host stellar system, the idea of the co-evolution of elliptical galaxies and of their SMBHs has become a central topic of modern astrophysics. Here, I summarize some consequences that can be derived from the galaxy Scaling Laws (SLs) and present a coherent scenario for the formation and evolution of elliptical galaxies and their central SMBHs, focusing in particular on the establishment and maintenance of their SLs. In particular, after a first observationally based part, the discussion focuses on the physical interpretation of the Fundamental Plane. Then, two important processes in principle able to destroy the galaxy and SMBH SLs, namely galaxy merging and cooling flows, are analyzed. Arguments supporting the necessity to clearly distinguish between the origin and maintenance of the different SLs, and the unavoidable occurrence of SMBH feedback on the galaxy ISM in the late stages of galaxy evolution (when elliptical galaxies are sometimes considered as dead, red objects), are then presented. At the end of the paper I will discuss some implications of the recent discovery of super-dense ellipticals in the distant Universe. In particular, I will argue that, if confirmed, these new observations would lead to the conclusion that at early epochs a relation between the stellar mass of the galaxy and the mass of the central SMBH should hold, consistent with the present day Magorrian relation, while the proportionality coefficient between M BH and the scale of velocity dispersion of the hosting spheroids should be significantly smaller than that at the present epoch

Champagne Pool (New Zealand) Thermophiles Yield Insights into the Evolution of Microbial Arsenic Resistance

Science.gov (United States)

Hug, K.; Krikowa, F.; Morgan, X.; Maher, W. A.; Stott, M. B.; Moreau, J. W.

2011-12-01

Arsenic is a highly toxic metalloid typically enriched in geothermal waters due to aqueous weathering of arsenic-bearing minerals. Investigation of enzymatic pathways by which thermophilic microorganisms cope with toxic arsenic levels may yield insights into the evolution of arsenic resistance mechanisms on the early Earth. At Wai-O-Tapu in the Taupo Volcanic Zone on the North Island of New Zealand, hot springs with temperatures of 30-90°C and elemental sulfur concentrations (expressed as equivalent sulfate) from 340 to 850 mg/l establish a range of environmental conditions. Total arsenic concentrations varied from 0.083 mg/l to 56 mg/l. Arsenic speciation analysis elucidated various biogeochemical arsenic transformations occurring within different springs. For example, in the Alum Cliff spring oxidizing conditions (Eh = 225 mV) were expected to stabilize dissolved arsenate (AsO43-). However, HPLC-ICPMS analyses yielded dissolved arsenate and arsenite (AsO33-) concentrations of 0.25 mg/l versus 43.3 mg/l, respectively, and point towards microbial arsenate reduction as the likely mechanism for arsenic redox transformation. 16S rRNA gene cloning of Alum Cliff DNA showed a predominantly archaeal population with the dominant clone "AC1_A1" most closely related (99% sequence similarity, NCBI BLAST°) to the uncultured Sulfolobus clone "ChP_97P" found in Champagne Pool (Childs et al., 2008). The closest isolated relative to AC1_A1 is Sulfolobus tokodaii str. TW with a sequence similarity of 94%. Arsenic speciation measurements from the Alum Cliff spring suggest that clone AC1_A1 features the arsenate reduction resistance mechanism, and we hypothesize therefore that an arsC (homolog or analog) provides this functionality. The organic arsenic species monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA), detected via HPLC-ICPMS at concentrations ranging from 1 μg/l to 12 μg/l in various springs, may also implicate microbial methyl-group transfers as an active

The geotectonic evolution of southern part of Sao Francisco Craton, based in geochronologic interpretation

International Nuclear Information System (INIS)

Teixeira, W.

1985-01-01

Interpretation of available radiometric data from poly metamorphic terranes of southern part of the Sao Francisco Craton demonstrates the importance of geochronology as a tool in the study of ancient crustal evolution. In addition, radiometric study of basic intrusive magmatism helps define the most important epochs of crustal rifting during the Proterozoic. The definition of the southern border of the cratonic area based on distinctive age patterns of the geochronological provinces is also discussed. Finally, the geochronologic evolution of the Bambui platform cover is presented. Approximately 250 radiometric age determinations (Rb-Sr, K-Ar and Pb-Pb methods) were interpreted principally through the use of iso chronic diagrams. The geologic history tectonomagnetic events identified in this study is compared to the crustal evolution of similar segments of the Sao Francisco Craton and elsewhere. (author)

Whole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity.

Directory of Open Access Journals (Sweden)

Jessica N Ricaldi

Full Text Available The whole genome analysis of two strains of the first intermediately pathogenic leptospiral species to be sequenced (Leptospira licerasiae strains VAR010 and MMD0835 provides insight into their pathogenic potential and deepens our understanding of leptospiral evolution. Comparative analysis of eight leptospiral genomes shows the existence of a core leptospiral genome comprising 1547 genes and 452 conserved genes restricted to infectious species (including L. licerasiae that are likely to be pathogenicity-related. Comparisons of the functional content of the genomes suggests that L. licerasiae retains several proteins related to nitrogen, amino acid and carbohydrate metabolism which might help to explain why these Leptospira grow well in artificial media compared with pathogenic species. L. licerasiae strains VAR010(T and MMD0835 possess two prophage elements. While one element is circular and shares homology with LE1 of L. biflexa, the second is cryptic and homologous to a previously identified but unnamed region in L. interrogans serovars Copenhageni and Lai. We also report a unique O-antigen locus in L. licerasiae comprised of a 6-gene cluster that is unexpectedly short compared with L. interrogans in which analogous regions may include >90 such genes. Sequence homology searches suggest that these genes were acquired by lateral gene transfer (LGT. Furthermore, seven putative genomic islands ranging in size from 5 to 36 kb are present also suggestive of antecedent LGT. How Leptospira become naturally competent remains to be determined, but considering the phylogenetic origins of the genes comprising the O-antigen cluster and other putative laterally transferred genes, L. licerasiae must be able to exchange genetic material with non-invasive environmental bacteria. The data presented here demonstrate that L. licerasiae is genetically more closely related to pathogenic than to saprophytic Leptospira and provide insight into the genomic bases for

A primitive endogenous lentivirus in a colugo: insights into the early evolution of lentiviruses.

Science.gov (United States)

Han, Guan-Zhu; Worobey, Michael

2015-01-01

Lentiviruses infect a wide range of mammal species. Much remains unknown about their deep history and host distribution. Here, we report the discovery of an endogenous lentivirus within the genome of the Sunda flying lemur (Galeopterus variegatus) (which we designate "Galeopterus variegatus endogenous lentivirus" [GvaELV]). We estimate the GvaELV genome invasion to have occurred more than 14 Ma, supporting an ancient origin of the lentivirus clade and an ancient lentiviral infection in colugo. Phylogenetic analyses show that GvaELV is a sister group of all previously known lentiviruses. The GvaELV genome appears to possess some primitive genomic features of a lentivirus, encoding not only a trans-activator of transcription (tat) gene but also two additional putative accessory genes that share no discernible similarity with other lentiviral accessory genes. The discovery of GvaELV provides novel insights into the prehistory and host distribution of lentivirus. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Persistent near-tropical warmth on the Antarctic continent during the early Eocene epoch.

Science.gov (United States)

Pross, Jörg; Contreras, Lineth; Bijl, Peter K; Greenwood, David R; Bohaty, Steven M; Schouten, Stefan; Bendle, James A; Röhl, Ursula; Tauxe, Lisa; Raine, J Ian; Huck, Claire E; van de Flierdt, Tina; Jamieson, Stewart S R; Stickley, Catherine E; van de Schootbrugge, Bas; Escutia, Carlota; Brinkhuis, Henk

2012-08-02

The warmest global climates of the past 65 million years occurred during the early Eocene epoch (about 55 to 48 million years ago), when the Equator-to-pole temperature gradients were much smaller than today and atmospheric carbon dioxide levels were in excess of one thousand parts per million by volume. Recently the early Eocene has received considerable interest because it may provide insight into the response of Earth's climate and biosphere to the high atmospheric carbon dioxide levels that are expected in the near future as a consequence of unabated anthropogenic carbon emissions. Climatic conditions of the early Eocene 'greenhouse world', however, are poorly constrained in critical regions, particularly Antarctica. Here we present a well-dated record of early Eocene climate on Antarctica from an ocean sediment core recovered off the Wilkes Land coast of East Antarctica. The information from biotic climate proxies (pollen and spores) and independent organic geochemical climate proxies (indices based on branched tetraether lipids) yields quantitative, seasonal temperature reconstructions for the early Eocene greenhouse world on Antarctica. We show that the climate in lowland settings along the Wilkes Land coast (at a palaeolatitude of about 70° south) supported the growth of highly diverse, near-tropical forests characterized by mesothermal to megathermal floral elements including palms and Bombacoideae. Notably, winters were extremely mild (warmer than 10 °C) and essentially frost-free despite polar darkness, which provides a critical new constraint for the validation of climate models and for understanding the response of high-latitude terrestrial ecosystems to increased carbon dioxide forcing.

When climate twitches, evolution takes great leaps

International Nuclear Information System (INIS)

Kerr, R.A.

1992-01-01

Earth's climate system has ridden a slow roller coaster for the past 60 million years. It warmed gradually until about 53 million years ago, reaching a peak that brought crocodiles to northern Canada; then it entered a long, undulating downgrade toward the ice-age world of the past few million years. Because the same span of time brought major evolutionary changes, including the rise of modern mammals, paleontologists have long assumed that these slow temperature changes helped spur the processes of evolution. But recent findings have suggested that another, more potent mechanisms was also at work: Abrupt climate excursions, superimposed on these long-term trends, have now been linked to rapid periods of mammal evolution. The evidence for short, sharp evolutionary shocks comes from studies of a pair of mirror-image climate shifts at opposite ends of the Eocene epoch, 55 million and 33.5 million years ago. In both cases, researchers studying the record of climate preserved in sea-floor sediments have found that a gradual climate change-warming in the first case, cooling in the second - suddenly steepened into a short-lived pulse of extreme warming or cooling. The short time scale of these events and their clear coincidence with turning points in the evolution of mammals are providing the tightest links yet between global climate change and evolution on land

The epoch of cosmic heating by early sources of X-rays

Science.gov (United States)

Eide, Marius B.; Graziani, Luca; Ciardi, Benedetta; Feng, Yu; Kakiichi, Koki; Di Matteo, Tiziana

2018-05-01

Observations of the 21 cm line from neutral hydrogen indicate that an epoch of heating (EoH) might have preceded the later epoch of reionization. Here we study the effects on the ionization state and the thermal history of the intergalactic medium (IGM) during the EoH induced by different assumptions on ionizing sources in the high-redshift Universe: (i) stars; (ii) X-ray binaries (XRBs); (iii) thermal bremsstrahlung of the hot interstellar medium (ISM); and (iv) accreting nuclear black holes (BHs). To this aim, we post-process outputs from the (100 h-1 comoving Mpc)3 hydrodynamical simulation MassiveBlack-II with the cosmological 3D radiative transfer code CRASH, which follows the propagation of ultraviolet and X-ray photons, computing the thermal and ionization state of hydrogen and helium through the EoH. We find that stars determine the fully ionized morphology of the IGM, while the spectrally hard XRBs pave way for efficient subsequent heating and ionization by the spectrally softer ISM. With the seeding prescription in MassiveBlack-II, BHs do not contribute significantly to either ionization or heating. With only stars, most of the IGM remains in a cold state (with a median T = 11 K at z = 10), however, the presence of more energetic sources raises the temperature of regions around the brightest and more clustered sources above that of the cosmic microwave background, opening the possibility to observing the 21 cm signal in emission.

Karyological characterization of the endemic Iberian rock lizard, Iberolacerta monticola (Squamata, Lacertidae): insights into sex chromosome evolution.

Science.gov (United States)

Rojo, V; Giovannotti, M; Naveira, H; Nisi Cerioni, P; González-Tizón, A M; Caputo Barucchi, V; Galán, P; Olmo, E; Martínez-Lage, A

2014-01-01

Rock lizards of the genus Iberolacerta constitute a promising model to examine the process of sex chromosome evolution, as these closely related taxa exhibit remarkable diversity in the degree of sex chromosome differentiation with no clear phylogenetic segregation, ranging from cryptic to highly heteromorphic ZW chromosomes and even multiple chromosome systems (Z1Z1Z2Z2/Z1Z2W). To gain a deeper insight into the patterns of karyotype and sex chromosome evolution, we performed a cytogenetic analysis based on conventional staining, banding techniques and fluorescence in situ hybridization in the species I. monticola, for which previous cytogenetic investigations did not detect differentiated sex chromosomes. The karyotype is composed of 2n = 36 acrocentric chromosomes. NORs and the major ribosomal genes were located in the subtelomeric region of chromosome pair 6. Hybridization signals of the telomeric sequences (TTAGGG)n were visualized at the telomeres of all chromosomes and interstitially in 5 chromosome pairs. C-banding showed constitutive heterochromatin at the centromeres of all chromosomes, as well as clear pericentromeric and light telomeric C-bands in several chromosome pairs. These results highlight some chromosomal markers which can be useful to identify species-specific diagnostic characters, although they may not accurately reflect the phylogenetic relationships among the taxa. In addition, C-banding revealed the presence of a heteromorphic ZW sex chromosome pair, where W is smaller than Z and almost completely heterochromatic. This finding sheds light on sex chromosome evolution in the genus Iberolacerta and suggests that further comparative cytogenetic analyses are needed to understand the processes underlying the origin, differentiation and plasticity of sex chromosome systems in lacertid lizards. © 2013 S. Karger AG, Basel.

Quasars: Cosmological evolution and x-ray background contribution

International Nuclear Information System (INIS)

Schmidt, M.; Green, R.F.

1986-01-01

The luminosity function of quasars varies with redshift or cosmic epoch. The authors discuss how the luminosity function and its evolution can be determined from complete samples of quasars. They first concentrate on optical survey of quasars. For quasars of medium luminosity, the co-moving space density rises very steeply with redshift. Quasars of lower luminosity exhibit a slower increase of density with redshift, resulting in luminosity-dependent evolution of the space density. They also discuss evidence for a cutoff of quasar redshift and for a possible dependence of the cutoff on luminosity. They evaluate X-ray counts of quasars and show the need for negative X-ray luminosity evolution in order to explain the counts and the low average redshifts of X-ray quasars. As a consequence, the quasar contribution to the X-ray background is lower than originally suspected. They discuss other extragalactic contributors to the X-ray background and conclude that they, together with the quasars, contribute about 60 percent of the observed background. About half of this is contributed by active galactic nuclei with optical luminosities below those of quasars

Cosmological evolution in vector-tensor theories of gravity

International Nuclear Information System (INIS)

Beltran Jimenez, Jose; Maroto, Antonio L.

2009-01-01

We present a detailed study of the cosmological evolution in general vector-tensor theories of gravity without potential terms. We consider the evolution of the vector field throughout the expansion history of the Universe and carry out a classification of models according to the behavior of the vector field in each cosmological epoch. We also analyze the case in which the Universe is dominated by the vector field, performing a complete analysis of the system phase map and identifying those attracting solutions which give rise to accelerated expansion. Moreover, we consider the evolution in a universe filled with a pressureless fluid in addition to the vector field and study the existence of attractors in which we can have a transition from matter domination to vector domination with accelerated expansion so that the vector field may play the role of dark energy. We find that the existence of solutions with late-time accelerated expansion is a generic prediction of vector-tensor theories and that such solutions typically lead to the presence of future singularities. Finally, limits from local gravity tests are used to get constraints on the value of the vector field at small (Solar System) scales.

Observational constraints on the cosmological evolution of extragalactic radio sources

International Nuclear Information System (INIS)

Perryman, M.A.C.

1979-11-01

The thesis discusses statistical studies of the remote radio sources, taking into account the various parameters for such sources, based on data from the various Cambridge Catalogues. Some of the sources have optical counterparts which yield distances from their redshifts. Combining optical and radio observations, an attempt is made to investigate whether large-scale evolution of galaxies occurs as one looks backwards in time to early epochs. Special attention is paid to ensuring that the optical identifications of the selected radio sources are sound and that the selection procedures do not distort the inferences obtained. (U.K.)

The sea cucumber genome provides insights into morphological evolution and visceral regeneration.

Science.gov (United States)

Zhang, Xiaojun; Sun, Lina; Yuan, Jianbo; Sun, Yamin; Gao, Yi; Zhang, Libin; Li, Shihao; Dai, Hui; Hamel, Jean-François; Liu, Chengzhang; Yu, Yang; Liu, Shilin; Lin, Wenchao; Guo, Kaimin; Jin, Songjun; Xu, Peng; Storey, Kenneth B; Huan, Pin; Zhang, Tao; Zhou, Yi; Zhang, Jiquan; Lin, Chenggang; Li, Xiaoni; Xing, Lili; Huo, Da; Sun, Mingzhe; Wang, Lei; Mercier, Annie; Li, Fuhua; Yang, Hongsheng; Xiang, Jianhai

2017-10-01

Apart from sharing common ancestry with chordates, sea cucumbers exhibit a unique morphology and exceptional regenerative capacity. Here we present the complete genome sequence of an economically important sea cucumber, A. japonicus, generated using Illumina and PacBio platforms, to achieve an assembly of approximately 805 Mb (contig N50 of 190 Kb and scaffold N50 of 486 Kb), with 30,350 protein-coding genes and high continuity. We used this resource to explore key genetic mechanisms behind the unique biological characters of sea cucumbers. Phylogenetic and comparative genomic analyses revealed the presence of marker genes associated with notochord and gill slits, suggesting that these chordate features were present in ancestral echinoderms. The unique shape and weak mineralization of the sea cucumber adult body were also preliminarily explained by the contraction of biomineralization genes. Genome, transcriptome, and proteome analyses of organ regrowth after induced evisceration provided insight into the molecular underpinnings of visceral regeneration, including a specific tandem-duplicated prostatic secretory protein of 94 amino acids (PSP94)-like gene family and a significantly expanded fibrinogen-related protein (FREP) gene family. This high-quality genome resource will provide a useful framework for future research into biological processes and evolution in deuterostomes, including remarkable regenerative abilities that could have medical applications. Moreover, the multiomics data will be of prime value for commercial sea cucumber breeding programs.

The sea cucumber genome provides insights into morphological evolution and visceral regeneration.

Directory of Open Access Journals (Sweden)

Xiaojun Zhang

2017-10-01

Full Text Available Apart from sharing common ancestry with chordates, sea cucumbers exhibit a unique morphology and exceptional regenerative capacity. Here we present the complete genome sequence of an economically important sea cucumber, A. japonicus, generated using Illumina and PacBio platforms, to achieve an assembly of approximately 805 Mb (contig N50 of 190 Kb and scaffold N50 of 486 Kb, with 30,350 protein-coding genes and high continuity. We used this resource to explore key genetic mechanisms behind the unique biological characters of sea cucumbers. Phylogenetic and comparative genomic analyses revealed the presence of marker genes associated with notochord and gill slits, suggesting that these chordate features were present in ancestral echinoderms. The unique shape and weak mineralization of the sea cucumber adult body were also preliminarily explained by the contraction of biomineralization genes. Genome, transcriptome, and proteome analyses of organ regrowth after induced evisceration provided insight into the molecular underpinnings of visceral regeneration, including a specific tandem-duplicated prostatic secretory protein of 94 amino acids (PSP94-like gene family and a significantly expanded fibrinogen-related protein (FREP gene family. This high-quality genome resource will provide a useful framework for future research into biological processes and evolution in deuterostomes, including remarkable regenerative abilities that could have medical applications. Moreover, the multiomics data will be of prime value for commercial sea cucumber breeding programs.

The Shock Dynamics of Heterogeneous YSO Jets: 3D Simulations Meet Multi-epoch Observations

Energy Technology Data Exchange (ETDEWEB)

Hansen, E. C.; Frank, A. [Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627-0171 (United States); Hartigan, P. [Department of Physics and Astronomy, Rice University, 6100 S. Main, Houston, TX 77521-1892 (United States); Lebedev, S. V. [Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2BW (United Kingdom)

2017-03-10

High-resolution observations of young stellar object (YSO) jets show them to be composed of many small-scale knots or clumps. In this paper, we report results of 3D numerical simulations designed to study how such clumps interact and create morphologies and kinematic patterns seen in emission line observations. Our simulations focus on clump scale dynamics by imposing velocity differences between spherical, over-dense regions, which then lead to the formation of bow shocks as faster clumps overtake slower material. We show that much of the spatial structure apparent in emission line images of jets arises from the dynamics and interactions of these bow shocks. Our simulations show a variety of time-dependent features, including bright knots associated with Mach stems where the shocks intersect, a “frothy” emission structure that arises from the presence of the Nonlinear Thin Shell Instability along the surfaces of the bow shocks, and the merging and fragmentation of clumps. Our simulations use a new non-equilibrium cooling method to produce synthetic emission maps in H α and [S ii]. These are directly compared to multi-epoch Hubble Space Telescope observations of Herbig–Haro jets. We find excellent agreement between features seen in the simulations and the observations in terms of both proper motion and morphologies. Thus we conclude that YSO jets may be dominated by heterogeneous structures and that interactions between these structures and the shocks they produce can account for many details of YSO jet evolution.

Nonlinear evolution of large-scale structure in the universe

International Nuclear Information System (INIS)

Frenk, C.S.; White, S.D.M.; Davis, M.

1983-01-01

Using N-body simulations we study the nonlinear development of primordial density perturbation in an Einstein--de Sitter universe. We compare the evolution of an initial distribution without small-scale density fluctuations to evolution from a random Poisson distribution. These initial conditions mimic the assumptions of the adiabatic and isothermal theories of galaxy formation. The large-scale structures which form in the two cases are markedly dissimilar. In particular, the correlation function xi(r) and the visual appearance of our adiabatic (or ''pancake'') models match better the observed distribution of galaxies. This distribution is characterized by large-scale filamentary structure. Because the pancake models do not evolve in a self-similar fashion, the slope of xi(r) steepens with time; as a result there is a unique epoch at which these models fit the galaxy observations. We find the ratio of cutoff length to correlation length at this time to be lambda/sub min//r 0 = 5.1; its expected value in a neutrino dominated universe is 4(Ωh) -1 (H 0 = 100h km s -1 Mpc -1 ). At early epochs these models predict a negligible amplitude for xi(r) and could explain the lack of measurable clustering in the Lyα absorption lines of high-redshift quasars. However, large-scale structure in our models collapses after z = 2. If this collapse precedes galaxy formation as in the usual pancake theory, galaxies formed uncomfortably recently. The extent of this problem may depend on the cosmological model used; the present series of experiments should be extended in the future to include models with Ω<1

The evolution of voids in the adhesion approximation

Science.gov (United States)

Sahni, Varun; Sathyaprakah, B. S.; Shandarin, Sergei F.

1994-08-01

We apply the adhesion approximation to study the formation and evolution of voids in the universe. Our simulations-carried out using 1283 particles in a cubical box with side 128 Mpc-indicate that the void spectrum evolves with time and that the mean void size in the standard Cosmic Background Explorer Satellite (COBE)-normalized cold dark matter (CDM) model with H50 = 1 scals approximately as bar D(z) = bar Dzero/(1+2)1/2, where bar Dzero approximately = 10.5 Mpc. Interestingly, we find a strong correlation between the sizes of voids and the value of the primordial gravitational potential at void centers. This observation could in principle, pave the way toward reconstructing the form of the primordial potential from a knowledge of the observed void spectrum. Studying the void spectrum at different cosmological epochs, for spectra with a built in k-space cutoff we find that the number of voids in a representative volume evolves with time. The mean number of voids first increases until a maximum value is reached (indicating that the formation of cellular structure is complete), and then begins to decrease as clumps and filaments erge leading to hierarchical clustering and the subsequent elimination of small voids. The cosmological epoch characterizing the completion of cellular structure occurs when the length scale going nonlinear approaches the mean distance between peaks of the gravitaional potential. A central result of this paper is that voids can be populated by substructure such as mini-sheets and filaments, which run through voids. The number of such mini-pancakes that pass through a given void can be measured by the genus characteristic of an individual void which is an indicator of the topology of a given void in intial (Lagrangian) space. Large voids have on an average a larger measure than smaller voids indicating more substructure within larger voids relative to smaller ones. We find that the topology of individual voids is strongly epoch dependent

Different habitats within a region contain evolutionary heritage from different epochs depending on the abiotic environment

NARCIS (Netherlands)

Bartish, I.V.; Ozinga, W.A.; Bartish, M.I.; Wamelink, G.W.W.; Hennekens, S.M.; Prinzing, Andreas

2016-01-01

Aim: Biodiversity hot-spots are regions containing evolutionary heritage from ancient or recent geological epochs, i.e. evolutionary 'museums' or 'cradles', respectively. We hypothesize that: (1) there are also 'museums' and 'cradles' within regions - some species pools of particular habitat

Ancient duplications and functional divergence in the interferon regulatory factors of vertebrates provide insights into the evolution of vertebrate immune systems.

Science.gov (United States)

Du, Kang; Zhong, Zaixuan; Fang, Chengchi; Dai, Wei; Shen, Yanjun; Gan, Xiaoni; He, Shunping

2018-04-01

Interferon regulatory factors (IRFs) were first discovered as transcription factors that regulate the transcription of human interferon (IFN)-β. Increasing evidence shows that they might be important players involved in Adaptive immune system (AIS) evolution. Although numbers of IRFs have been identified in chordates, the evolutionary history and functional diversity of this gene family during the early evolution of vertebrates have remained obscure. Using IRF HMM profile and HMMER searches, we identified 148 IRFs in 11 vertebrates and 4 protochordates. For them, we reconstructed the phylogenetic relationships, determined the synteny conservation, investigated the profile of natural selection, and analyzed the expression patterns in four "living fossil" vertebrates: lamprey, elephant shark, coelacanth and bichir. The results from phylogeny and synteny analysis imply that vertebrate IRFs evolved from three predecessors, instead of four as suggested in a previous study, as results from an ancient duplication followed by special expansions and lost during the vertebrate evolution. The profile of natural selection and expression reveals functional dynamics during the process. Together, they suggest that the 2nd whole-genome duplication (2WGD) provided raw materials for innovation in the IRF family, and that the birth of type-I IFN might be an important factor inducing the establishment of IRF-mediated immune networks. As a member involved in the AIS evolution, IRF provide insights into the process and mechanism involved in the complexity and novelties of vertebrate immune systems. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

The Evolution of the Faint End of the UV Luminosity Function during the Peak Epoch of Star Formation (1 < z < 3)

Science.gov (United States)

Alavi, Anahita; Siana, Brian; Richard, Johan; Rafelski, Marc; Jauzac, Mathilde; Limousin, Marceau; Freeman, William R.; Scarlata, Claudia; Robertson, Brant; Stark, Daniel P.; Teplitz, Harry I.; Desai, Vandana

2016-11-01

We present a robust measurement of the rest-frame UV luminosity function (LF) and its evolution during the peak epoch of cosmic star formation at 1\\lt z\\lt 3. We use our deep near-ultraviolet imaging from WFC3/UVIS on the Hubble Space Telescope and existing Advanced Camera for Surveys (ACS)/WFC and WFC3/IR imaging of three lensing galaxy clusters, Abell 2744 and MACS J0717 from the Hubble Frontier Field survey and Abell 1689. Combining deep UV imaging and high magnification from strong gravitational lensing, we use photometric redshifts to identify 780 ultra-faint galaxies with {M}{UV}\\lt -12.5 AB mag at 1\\lt z\\lt 3. From these samples, we identified five new, faint, multiply imaged systems in A1689. We run a Monte Carlo simulation to estimate the completeness correction and effective volume for each cluster using the latest published lensing models. We compute the rest-frame UV LF and find the best-fit faint-end slopes of α =-1.56+/- 0.04, α =-1.72+/- 0.04, and α =-1.94+/- 0.06 at 1.0\\lt z\\lt 1.6, 1.6\\lt z\\lt 2.2, and 2.2\\lt z\\lt 3.0, respectively. Our results demonstrate that the UV LF becomes steeper from z˜ 1.3 to z˜ 2.6 with no sign of a turnover down to {M}{UV}=-14 AB mag. We further derive the UV LFs using the Lyman break “dropout” selection and confirm the robustness of our conclusions against different selection methodologies. Because the sample sizes are so large and extend to such faint luminosities, the statistical uncertainties are quite small, and systematic uncertainties (due to the assumed size distribution, for example) likely dominate. If we restrict our analysis to galaxies and volumes above \\gt 50 % completeness in order to minimize these systematics, we still find that the faint-end slope is steep and getting steeper with redshift, though with slightly shallower (less negative) values (α =-1.55+/- 0.06, -1.69 ± 0.07, and -1.79 ± 0.08 for z˜ 1.3, 1.9, and 2.6, respectively). Finally, we conclude that the faint star

Emergence and Evolution

DEFF Research Database (Denmark)

Bullwinkle, Tammy J; Ibba, Michael

2013-01-01

ancestor and as such they provide insights into the evolution and development of the extant genetic code. Although the aaRSs have long been viewed as a highly conserved group of enzymes, findings within the last couple of decades have started to demonstrate how diverse and versatile these enzymes really...... are. Beyond their central role in translation, aaRSs and their numerous homologs have evolved a wide array of alternative functions both inside and outside translation. Current understanding of the emergence of the aaRSs, and their subsequent evolution into a functionally diverse enzyme family...

A Method for Exploring Program and Portfolio Affordability Tradeoffs Under Uncertainty Using Epoch-Era Analysis: A Case Application to Carrier Strike Group Design

Science.gov (United States)

2015-04-30

design for affordability by augmenting Epoch-Era Analysis with aspects of Modern Portfolio Theory . The method is demonstrated through the design of a...introduces a method to conduct portfolio design for affordability by augmenting Epoch-Era Analysis with aspects of Modern Portfolio Theory . The method...through the integration of elements of Modern Portfolio Theory (MPT) and the SoS design literature. The proposed method is demonstrated in a case study

Schubert and Beethoven - Adorno’s early antipods of the music in bougeois epoch

Directory of Open Access Journals (Sweden)

Jeremić-Molnar Dragana

2012-01-01

Full Text Available In this article the authors are reconstructing the dichotomies which the young Theodor Adorno was trying to detect in the music of the bourgeois epoch and personify in two antipodes - Franz Schubert and Ludwig van Beethoven. Although already a devotee of Arnold Schönberg and the 20th century music avantgardism, Adorno was, in his works prior to his exile from Germany (1934, intensively dealing with Schubert and his opposition towards Beethoven. While Beethoven was a bold and progressive revolutionary, fascinated by the “practical reason” and the mission to rise up and reach the stars, Schubert wanted none of it (almost anticipating the failure of the whole revolutionary project. Instead, he was looking backwards, to primordial nature and the possibility of man to participate in its mythic cycles of death and regeneration. The lack of synthesis between this two opposing tendencies in the music of early bourgeois epoch lead to the “negative dialectics” of Schönberg and 20th century music avantgardism and to the final separation of Beethovenian musical progress and Schubertian musical mimesis. [Projekat Ministarstva nauke Republike Srbije, br. 177019: Identiteti srpske muzike u svetskom kulturnom kontekstu, i br. 179035: Izazovi nove društvene integracije u Srbiji - koncepti i akteri

Insights into the evolution of Darwin’s finches from comparative analysis of the Geospiza magnirostris genome sequence

Directory of Open Access Journals (Sweden)

Rands Chris M

2013-02-01

Full Text Available Abstract Background A classical example of repeated speciation coupled with ecological diversification is the evolution of 14 closely related species of Darwin’s (Galápagos finches (Thraupidae, Passeriformes. Their adaptive radiation in the Galápagos archipelago took place in the last 2–3 million years and some of the molecular mechanisms that led to their diversification are now being elucidated. Here we report evolutionary analyses of genome of the large ground finch, Geospiza magnirostris. Results 13,291 protein-coding genes were predicted from a 991.0 Mb G. magnirostris genome assembly. We then defined gene orthology relationships and constructed whole genome alignments between the G. magnirostris and other vertebrate genomes. We estimate that 15% of genomic sequence is functionally constrained between G. magnirostris and zebra finch. Genic evolutionary rate comparisons indicate that similar selective pressures acted along the G. magnirostris and zebra finch lineages suggesting that historical effective population size values have been similar in both lineages. 21 otherwise highly conserved genes were identified that each show evidence for positive selection on amino acid changes in the Darwin's finch lineage. Two of these genes (Igf2r and Pou1f1 have been implicated in beak morphology changes in Darwin’s finches. Five of 47 genes showing evidence of positive selection in early passerine evolution have cilia related functions, and may be examples of adaptively evolving reproductive proteins. Conclusions These results provide insights into past evolutionary processes that have shaped G. magnirostris genes and its genome, and provide the necessary foundation upon which to build population genomics resources that will shed light on more contemporaneous adaptive and non-adaptive processes that have contributed to the evolution of the Darwin’s finches.

MULTI-EPOCH IMAGING POLARIMETRY OF THE SiO MASERS IN THE EXTENDED ATMOSPHERE OF THE MIRA VARIABLE TX CAM

International Nuclear Information System (INIS)

Kemball, Athol J.; Diamond, Philip J.; Gonidakis, Ioannis; Mitra, Modhurita; Yim, Kijeong; Pan, K.-C.; Chiang, H.-F.

2009-01-01

We present a time series of synoptic images of the linearly polarized v = 1, J = 1-0 SiO maser emission toward the Mira variable, TX Cam. These data comprise 43 individual epochs at an approximate biweekly sampling over an optical pulsation phase range of φ = 0.68 to φ = 1.82. The images have an angular resolution of ∼500 μas and were obtained using the Very Long Baseline Array (VLBA), operating in the 43 GHz band in spectral-line, polarization mode. We have previously published the total intensity time series for this pulsation phase range; this paper serves to present the linearly polarized image sequence and an associated animation representing the evolution of the linear polarization morphology over time. We find a predominantly tangential polarization morphology, a high degree of persistence in linear polarization properties over individual component lifetimes, and stronger linear polarization in the inner projected shell than at larger projected shell radii. We present an initial polarization proper motion analysis examining the possible dynamical influence of magnetic fields in component motions in the extended atmospheres of late-type, evolved stars.

Links between galaxy evolution, morphology and internal physical processes

International Nuclear Information System (INIS)

Kraljic, Katarina

2014-01-01

This thesis aims at making the link between galaxy evolution, morphology and internal physical processes, namely star formation as the outcome of the turbulent multiphase interstellar medium, using the cosmological zoom-in simulations, simulations of isolated and merging galaxies, and the analytic model of star formation. In Chapter 1, I explain the motivation for this thesis and briefly review the necessary background related to galaxy formation and modeling with the use of numerical simulations. I first explore the evolution of the morphology of Milky-Way-mass galaxies in a suite of zoom-in cosmological simulations through the analysis of bars. I analyze the evolution of the fraction of bars with redshift, its dependence on the stellar mass and accretion history of individual galaxies. I show in particular, that the fraction of bars declines with increasing redshift, in agreement with the observations. This work also shows that the obtained results suggest that the bar formation epoch corresponds to the transition between an early 'violent' phase of spiral galaxies formation at z > 1, during which they are often disturbed by major mergers or multiple minor mergers as well as violent disk instabilities, and a late 'secular' phase at z [fr

Reading the metal diaries of the universe : tracing cosmic chemical evolution from the reionization epoch till the present

NARCIS (Netherlands)

Vink, J.

2009-01-01

Metals are essential for star formation and their subsequent evolution, and ultimately the formation of planets and the development of life, as we know it. Reconstructing the cosmic history of metals, reaching from the first population of stars to the processes involved in the formation of galaxies

A fast pulse phase estimation method for X-ray pulsar signals based on epoch folding

Directory of Open Access Journals (Sweden)

Xue Mengfan

2016-06-01

Full Text Available X-ray pulsar-based navigation (XPNAV is an attractive method for autonomous deep-space navigation in the future. The pulse phase estimation is a key task in XPNAV and its accuracy directly determines the navigation accuracy. State-of-the-art pulse phase estimation techniques either suffer from poor estimation accuracy, or involve the maximization of generally non-convex object function, thus resulting in a large computational cost. In this paper, a fast pulse phase estimation method based on epoch folding is presented. The statistical properties of the observed profile obtained through epoch folding are developed. Based on this, we recognize the joint probability distribution of the observed profile as the likelihood function and utilize a fast Fourier transform-based procedure to estimate the pulse phase. Computational complexity of the proposed estimator is analyzed as well. Experimental results show that the proposed estimator significantly outperforms the currently used cross-correlation (CC and nonlinear least squares (NLS estimators, while significantly reduces the computational complexity compared with NLS and maximum likelihood (ML estimators.

The E-MOSAICS project: simulating the formation and co-evolution of galaxies and their star cluster populations

Science.gov (United States)

Pfeffer, Joel; Kruijssen, J. M. Diederik; Crain, Robert A.; Bastian, Nate

2018-04-01

We introduce the MOdelling Star cluster population Assembly In Cosmological Simulations within EAGLE (E-MOSAICS) project. E-MOSAICS incorporates models describing the formation, evolution, and disruption of star clusters into the EAGLE galaxy formation simulations, enabling the examination of the co-evolution of star clusters and their host galaxies in a fully cosmological context. A fraction of the star formation rate of dense gas is assumed to yield a cluster population; this fraction and the population's initial properties are governed by the physical properties of the natal gas. The subsequent evolution and disruption of the entire cluster population are followed accounting for two-body relaxation, stellar evolution, and gravitational shocks induced by the local tidal field. This introductory paper presents a detailed description of the model and initial results from a suite of 10 simulations of ˜L⋆ galaxies with disc-like morphologies at z = 0. The simulations broadly reproduce key observed characteristics of young star clusters and globular clusters (GCs), without invoking separate formation mechanisms for each population. The simulated GCs are the surviving population of massive clusters formed at early epochs (z ≳ 1-2), when the characteristic pressures and surface densities of star-forming gas were significantly higher than observed in local galaxies. We examine the influence of the star formation and assembly histories of galaxies on their cluster populations, finding that (at similar present-day mass) earlier-forming galaxies foster a more massive and disruption-resilient cluster population, while galaxies with late mergers are capable of forming massive clusters even at late cosmic epochs. We find that the phenomenological treatment of interstellar gas in EAGLE precludes the accurate modelling of cluster disruption in low-density environments, but infer that simulations incorporating an explicitly modelled cold interstellar gas phase will overcome

Evolution and Education

Science.gov (United States)

Washburn, S. L.

1974-01-01

Education should give an understanding of the world and of man, as well as offer the vocational training, at which the university excells. The use of case studies to provide immediate insight into advancing knowledge and the study of evolution have important instructional and educational implication for the goal of understanding man. (JH)

Superposed epoch analysis of O+ auroral outflow during sawtooth events and substorms

Science.gov (United States)

Nowrouzi, N.; Kistler, L. M.; Lund, E. J.; Cai, X.

2017-12-01

Sawtooth events are repeated injection of energetic particles at geosynchronous orbit. Studies have shown that 94% of sawtooth events occurred during magnetic storm times. The main factor that causes a sawtooth event is still an open question. Simulations have suggested that heavy ions like O+ may play a role in triggering the injections. One of the sources of the O+ in the Earth's magnetosphere is the nightside aurora. O+ ions coming from the nightside auroral region have direct access to the near-earth magnetotail. A model (Brambles et al. 2013) for interplanetary coronal mass ejection driven sawtooth events found that nightside O+ outflow caused the subsequent teeth of the sawtooth event through a feedback mechanism. This work is a superposed epoch analysis to test whether the observed auroral outflow supports this model. Using FAST spacecraft data from 1997-2007, we examine the auroral O+ outflow as a function of time relative to an injection onset. Then we determine whether the profile of outflow flux of O+ during sawtooth events is different from the outflow observed during isolated substorms. The auroral region boundaries are estimated using the method of (Andersson et al. 2004). Subsequently the O+ outflow flux inside these boundaries are calculated and binned as a function of superposed epoch time for substorms and sawtooth "teeth". In this way, we will determine if sawtooth events do in fact have greater O+ outflow, and if that outflow is predominantly from the nightside, as suggested by the model results.

Evolution of subsidiary competences

DEFF Research Database (Denmark)

Geisler Asmussen, Christian; Pedersen, Torben; Dhanaraj, Charles

of competitive advantage of nations, we hypothesize the contingencies under which heterogeneity in host environments influences subsidiary competence configuration. We test our model with data from more than 2,000 subsidiaries in seven Western European countries. Our results provide new insights on the evolution...

Kinship and Human Evolution

DEFF Research Database (Denmark)

Bergendorff, Steen

This book offers a exiting new explanation of human evolution. Based on insight from Anthropology is shows that human became 'cultured' beings capable of symbolic thought by developing rasting kinship based between groups that could not other wise survive in the harah climate condition during...

Satellite- and Epoch Differenced Precise Point Positioning Based on a Regional Augmentation Network

Directory of Open Access Journals (Sweden)

Bin Wu

2012-06-01

Full Text Available Precise Point Positioning (PPP has been demonstrated as a simple and effective approach for user positioning. The key issue in PPP is how to shorten convergence time and improve positioning efficiency. Recent researches mainly focus on the ambiguity resolution by correcting residual phase errors at a single station. The success of this approach (referred to hereafter as NORM-PPP is subject to how rapidly one can fix wide-lane and narrow-lane ambiguities to achieve the first ambiguity-fixed solution. The convergence time of NORM-PPP is receiver type dependent, and normally takes 15–20 min. Different from the general algorithm and theory by which the float ambiguities are estimated and the integer ambiguities are fixed, we concentrate on a differential PPP approach: the satellite- and epoch differenced (SDED approach. In general, the SDED approach eliminates receiver clocks and ambiguity parameters and thus avoids the complicated residual phase modeling procedure. As a further development of the SDED approach, we use a regional augmentation network to derive tropospheric delay and remaining un-modeled errors at user sites. By adding these corrections and applying the Robust estimation, the weak mathematic properties due to the ED operation is much improved. Implementing this new approach, we need only two epochs of data to achieve PPP positioning converging to centimeter-positioning accuracy. Using seven days of GPS data at six CORS stations in Shanghai, we demonstrate the success rate, defined as the case when three directions converging to desired positioning accuracy of 10 cm, reaches 100% when the interval between the two epochs is longer than 15 min. Comparing the results of 15 min’ interval to that of 10 min’, it is observed that the position RMS improves from 2.47, 3.95, 5.78 cm to 2.21, 3.93, 4.90 cm in the North, East and Up directions, respectively. Combining the SDED coordinates at the starting point and the ED relative

Evolution of Flat Roofs

Directory of Open Access Journals (Sweden)

Şt. Vasiliu

2009-01-01

Full Text Available Roofs are constructive subassembles that are located at the top of buildings, which toghether with perimetral walls and some elements of the infrastructure belongs to the subsystem elements that close the building. Roofs must meet resistance requirements to mechanical action, thermal insulating, waterproofing and acoustic, fire resistance, durability, economy and aesthetics. The man saw the need to build roofs from the oldest ancient times. Even if the design of buildings has an empirical character, are known and are preserved until today constructions that are made in antiquity, by the Egyptians, Greeks and Romans with architectural achievements, worthy of admiration and in present time. General composition of civil construction has been influenced throughout the evolution of construction history by the level of production forces and properties of building materials available in every historical epoch. For over five millennia, building materials were stone, wood and ceramic products (concrete was used by theRomans only as filling material.

Enhancer evolution across 20 mammalian species

DEFF Research Database (Denmark)

Villar, Diego; Berthelot, Camille; Aldridge, Sarah

2015-01-01

The mammalian radiation has corresponded with rapid changes in noncoding regions of the genome, but we lack a comprehensive understanding of regulatory evolution in mammals. Here, we track the evolution of promoters and enhancers active in liver across 20 mammalian species from six diverse orders...... by profiling genomic enrichment of H3K27 acetylation and H3K4 trimethylation. We report that rapid evolution of enhancers is a universal feature of mammalian genomes. Most of the recently evolved enhancers arise from ancestral DNA exaptation, rather than lineage-specific expansions of repeat elements....... These results provide important insight into the functional genetics underpinning mammalian regulatory evolution....

ORIGIN: Metal Creation and Evolution from the Cosmic Dawn

DEFF Research Database (Denmark)

Herder, J. W. den; Piro, L.; Ohashi, T.

2011-01-01

, and beyond. The mission will answer questions such as: When were the first metals created? How does the cosmic metal content evolve? Where do most of the metals reside in the Universe? What is the role of metals in structure formation and evolution? To reach out to the early Universe ORIGIN will use Gamma......ORIGIN is a proposal for the M3 mission call of ESA aimed at the study of metal creation from the epoch of cosmic dawn. Using high-spectral resolution in the soft X-ray band, ORIGIN will be able to identify the physical conditions of all abundant elements between C and Ni to red-shifts of z=10...

Combinations of Epoch Durations and Cut-Points to Estimate Sedentary Time and Physical Activity among Adolescents

Science.gov (United States)

Fröberg, Andreas; Berg, Christina; Larsson, Christel; Boldemann, Cecilia; Raustorp, Anders

2017-01-01

The purpose of the current study was to investigate how combinations of different epoch durations and cut-points affect the estimations of sedentary time and physical activity in adolescents. Accelerometer data from 101 adolescents were derived and 30 combinations were used to estimate sedentary time, light, moderate, vigorous, and combined…

New insights into the stratigraphic, paleogeographic and tectonic evolution and petroleum potential of Kerkennah Islands, Eastern Tunisia

Science.gov (United States)

Elfessi, Maroua

2017-01-01

This work presents general insights into the stratigraphic and paleogeographic evolution as well as the structural architecture and the petroleum potential of Kerkennah Islands, located in the Eastern Tunisia Foreland, from Cenomanian to Pliocene times. Available data from twenty wells mostly drilled in Cercina and Chergui fields are used to establish three lithostratigraphic correlations as well as isopach and isobath maps in order to point out thickness and depth variations of different geological formations present within our study area; in addition to a synthetic log and isoporosity map of the main carbonate reservoir (the nummulites enriched Reineche Member). The integrated geological study reveals relatively condensed but generally continuous sedimentation and a rugged substrate with horsts, grabens and tilted blocks due to the initiation and the individualization of Kerkennah arch throughout the studied geological times. Furthermore, a relationship was highlighted between the evolution of our study zone and those of Sirt basin, Western Mediterranean Sea and Pelagian troughs; this relationship is due to the outstanding location of Kerkennah Islands. The main Bou Dabbous source rock is thicker and more mature within the central-east of the Gulf of Gabes indicating therefore the southeast charge of Reineche reservoir which shows NW-SE trending tilted block system surrounded by normal faults representing the hydrocarbon migration pathways. Besides, the thick Oligo-Miocene formations deposited during the collapse of the Pelagian block caused the maturation of the Ypresian source rock, while the Pliocene unconformity allowed basin inversion and hydrocarbon migration.

Adaptive laboratory evolution – principles and applications for biotechnology

Science.gov (United States)

2013-01-01

Adaptive laboratory evolution is a frequent method in biological studies to gain insights into the basic mechanisms of molecular evolution and adaptive changes that accumulate in microbial populations during long term selection under specified growth conditions. Although regularly performed for more than 25 years, the advent of transcript and cheap next-generation sequencing technologies has resulted in many recent studies, which successfully applied this technique in order to engineer microbial cells for biotechnological applications. Adaptive laboratory evolution has some major benefits as compared with classical genetic engineering but also some inherent limitations. However, recent studies show how some of the limitations may be overcome in order to successfully incorporate adaptive laboratory evolution in microbial cell factory design. Over the last two decades important insights into nutrient and stress metabolism of relevant model species were acquired, whereas some other aspects such as niche-specific differences of non-conventional cell factories are not completely understood. Altogether the current status and its future perspectives highlight the importance and potential of adaptive laboratory evolution as approach in biotechnological engineering. PMID:23815749

Insights into recent and ancient trends in the co-evolution of Earth and life as revealed by microbial genomics

Science.gov (United States)

Anderson, R. E.; Huber, J. A.; Parsons, C.; Stüeken, E.

2017-12-01

tree of life. In contrast, genes related to nitrogen fixation display much more consistent rates of horizontal gene transfer throughout Earth's history. Studies that couple genomics approaches with geochemistry have the potential to reveal insights into the co-evolution of life and Earth both in the recent and distant past.

Comparison of the Internal Dynamics of Metalloproteases Provides New Insights on Their Function and Evolution.

Directory of Open Access Journals (Sweden)

Henrique F Carvalho

Full Text Available Metalloproteases have evolved in a vast number of biological systems, being one of the most diverse types of proteases and presenting a wide range of folds and catalytic metal ions. Given the increasing understanding of protein internal dynamics and its role in enzyme function, we are interested in assessing how the structural heterogeneity of metalloproteases translates into their dynamics. Therefore, the dynamical profile of the clan MA type protein thermolysin, derived from an Elastic Network Model of protein structure, was evaluated against those obtained from a set of experimental structures and molecular dynamics simulation trajectories. A close correspondence was obtained between modes derived from the coarse-grained model and the subspace of functionally-relevant motions observed experimentally, the later being shown to be encoded in the internal dynamics of the protein. This prompted the use of dynamics-based comparison methods that employ such coarse-grained models in a representative set of clan members, allowing for its quantitative description in terms of structural and dynamical variability. Although members show structural similarity, they nonetheless present distinct dynamical profiles, with no apparent correlation between structural and dynamical relatedness. However, previously unnoticed dynamical similarity was found between the relevant members Carboxypeptidase Pfu, Leishmanolysin, and Botulinum Neurotoxin Type A, despite sharing no structural similarity. Inspection of the respective alignments shows that dynamical similarity has a functional basis, namely the need for maintaining proper intermolecular interactions with the respective substrates. These results suggest that distinct selective pressure mechanisms act on metalloproteases at structural and dynamical levels through the course of their evolution. This work shows how new insights on metalloprotease function and evolution can be assessed with comparison schemes that

OPENING THE 21 cm EPOCH OF REIONIZATION WINDOW: MEASUREMENTS OF FOREGROUND ISOLATION WITH PAPER

Energy Technology Data Exchange (ETDEWEB)

Pober, Jonathan C.; Parsons, Aaron R.; Ali, Zaki [Astronomy Department, U. California, Berkeley, CA (United States); Aguirre, James E.; Moore, David F. [Department of Physics and Astronomy, U. Pennsylvania, Philadelphia, PA (United States); Bradley, Richard F. [Department of Electrical and Computer Engineering, U. Virginia, Charlottesville, VA (United States); Carilli, Chris L. [National Radio Astronomy Observatory, Socorro, NM (United States); DeBoer, Dave; Dexter, Matthew; MacMahon, Dave [Radio Astronomy Laboratory, U. California, Berkeley, CA (United States); Gugliucci, Nicole E. [Department of Astronomy, U. Virginia, Charlottesville, VA (United States); Jacobs, Daniel C. [School of Earth and Space Exploration, Arizona State U., Tempe, AZ (United States); Klima, Patricia J. [National Radio Astronomy Observatory, Charlottesville, VA (United States); Manley, Jason; Walbrugh, William P. [Square Kilometer Array, South Africa Project, Cape Town (South Africa); Stefan, Irina I. [Cavendish Laboratory, Cambridge (United Kingdom)

2013-05-10

We present new observations with the Precision Array for Probing the Epoch of Reionization with the aim of measuring the properties of foreground emission for 21 cm epoch of reionization (EoR) experiments at 150 MHz. We focus on the footprint of the foregrounds in cosmological Fourier space to understand which modes of the 21 cm power spectrum will most likely be compromised by foreground emission. These observations confirm predictions that foregrounds can be isolated to a {sup w}edge{sup -}like region of two-dimensional (k , k{sub Parallel-To })-space, creating a window for cosmological studies at higher k{sub Parallel-To} values. We also find that the emission extends past the nominal edge of this wedge due to spectral structure in the foregrounds, with this feature most prominent on the shortest baselines. Finally, we filter the data to retain only this ''unsmooth'' emission and image its specific k{sub Parallel-To} modes. The resultant images show an excess of power at the lowest modes, but no emission can be clearly localized to any one region of the sky. This image is highly suggestive that the most problematic foregrounds for 21 cm EoR studies will not be easily identifiable bright sources, but rather an aggregate of fainter emission.

Insight into Evolution, Processing and Performance of Multi-length-scale Structures in Planar Heterojunction Perovskite Solar Cells.

Science.gov (United States)

Huang, Yu-Ching; Tsao, Cheng-Si; Cho, Yi-Ju; Chen, Kuan-Chen; Chiang, Kai-Ming; Hsiao, Sheng-Yi; Chen, Chang-Wen; Su, Chun-Jen; Jeng, U-Ser; Lin, Hao-Wu

2015-09-04

The structural characterization correlated to the processing control of hierarchical structure of planar heterojunction perovskite layer is still incomplete due to the limitations of conventional microscopy and X-ray diffraction. This present study performed the simultaneously grazing-incidence small-angle scattering and wide-angle scattering (GISAXS/GIWAXS) techniques to quantitatively probe the hierarchical structure of the planar heterojunction perovskite solar cells. The result is complementary to the currently microscopic study. Correlation between the crystallization behavior, crystal orientation, nano- and meso-scale internal structure and surface morphology of perovskite film as functions of various processing control parameters is reported for the first time. The structural transition from the fractal pore network to the surface fractal can be tuned by the chloride percentage. The GISAXS/GIWAXS measurement provides the comprehensive understanding of concurrent evolution of the film morphology and crystallization correlated to the high performance. The result can provide the insight into formation mechanism and rational synthesis design.

Insight into Evolution, Processing and Performance of Multi-length-scale Structures in Planar Heterojunction Perovskite Solar Cells

Science.gov (United States)

Huang, Yu-Ching; Tsao, Cheng-Si; Cho, Yi-Ju; Chen, Kuan-Chen; Chiang, Kai-Ming; Hsiao, Sheng-Yi; Chen, Chang-Wen; Su, Chun-Jen; Jeng, U.-Ser; Lin, Hao-Wu

2015-09-01

The structural characterization correlated to the processing control of hierarchical structure of planar heterojunction perovskite layer is still incomplete due to the limitations of conventional microscopy and X-ray diffraction. This present study performed the simultaneously grazing-incidence small-angle scattering and wide-angle scattering (GISAXS/GIWAXS) techniques to quantitatively probe the hierarchical structure of the planar heterojunction perovskite solar cells. The result is complementary to the currently microscopic study. Correlation between the crystallization behavior, crystal orientation, nano- and meso-scale internal structure and surface morphology of perovskite film as functions of various processing control parameters is reported for the first time. The structural transition from the fractal pore network to the surface fractal can be tuned by the chloride percentage. The GISAXS/GIWAXS measurement provides the comprehensive understanding of concurrent evolution of the film morphology and crystallization correlated to the high performance. The result can provide the insight into formation mechanism and rational synthesis design.

THE WYOMING SURVEY FOR Hα. III. A MULTI-WAVELENGTH LOOK AT ATTENUATION BY DUST IN GALAXIES OUT TO z ∼ 0.4

International Nuclear Information System (INIS)

Moore, Carolynn A.; Dale, Daniel A.; Barlow, Rebecca J.; Cohen, Seth A.; Cook, David O.; Johnson, L. C.; Kattner, ShiAnne M.; Staudaher, Shawn M.; Lee, Janice C.

2010-01-01

We report results from the Wyoming Survey for Hα (WySH), a comprehensive four-square degree survey to probe the evolution of star-forming galaxies over the latter half of the age of the universe. We have supplemented the Hα data from WySH with infrared data from the Spitzer Wide-area Infrared Extragalactic Survey and ultraviolet data from the Galaxy Evolution Explorer Deep Imaging Survey. This data set provides a multi-wavelength look at the evolution of the attenuation by dust, and here we compare a traditional measure of dust attenuation (L(TIR)/L(FUV)) to a diagnostic based on a recently developed robust star formation rate (SFR) indicator, [Ha obs +24μm]/Ha obs . With such data over multiple epochs, the evolution in the attenuation by dust with redshift can be assessed. We present results from the ELAIS-N1 and Lockman Hole regions at z ∼ 0.16, 0.24, 0.32, and 0.40. While the ensemble averages of both diagnostics are relatively constant from epoch to epoch, each epoch individually exhibits a larger attenuation by dust for higher SFRs. Hence, an epoch-to-epoch comparison at a fixed SFR suggests a mild decrease in dust attenuation with redshift.

Modelling the Course of an HIV Infection: Insights from Ecology and Evolution

Directory of Open Access Journals (Sweden)

Carsten Magnus

2012-10-01

Full Text Available The Human Immunodeficiency Virus (HIV is one of the most threatening viral agents. This virus infects approximately 33 million people, many of whom are unaware of their status because, except for flu-like symptoms right at the beginning of the infection during the acute phase, the disease progresses more or less symptom-free for 5 to 10 years. During this asymptomatic phase, the virus slowly destroys the immune system until the onset of AIDS when opportunistic infections like pneumonia or Kaposi’s sarcoma can overcome immune defenses. Mathematical models have played a decisive role in estimating important parameters (e.g., virion clearance rate or life-span of infected cells. However, most models only account for the acute and asymptomatic latency phase and cannot explain the progression to AIDS. Models that account for the whole course of the infection rely on different hypotheses to explain the progression to AIDS. The aim of this study is to review these models, present their technical approaches and discuss the robustness of their biological hypotheses. Among the few models capturing all three phases of an HIV infection, we can distinguish between those that mainly rely on population dynamics and those that involve virus evolution. Overall, the modeling quest to capture the dynamics of an HIV infection has improved our understanding of the progression to AIDS but, more generally, it has also led to the insight that population dynamics and evolutionary processes can be necessary to explain the course of an infection.

The variation of the baryon-to-photon ratio during different cosmological epochs due to decay and annihilation of dark matter

International Nuclear Information System (INIS)

Zavarygin, E O; Ivanchik, A V

2015-01-01

An influence of annihilation and decay of the dark matter particles on the baryon-to-photon ratio has been studied for different cosmological epochs. We consider the different parameter values of the dark matter particles such as mass, annihilation cross section, lifetime and so on. The obtained results are compared with the data which come from the Big Bang nucleosynthesis calculation and from the analysis of the anisotropy of the cosmic microwave background radiation. It has been shown that the modern value of the dark matter density Ω CDM = 0.26 is enough to provide the variation of the baryon-to-photon ratio up to Δη/η ∼ 0.01÷1 for decay of the dark matter particles, but it also leads to an excess of the diffuse gamma ray background. We use the observational data on the diffuse gamma ray background in order to determine our constraints on the model of the dark matter particle decay and on the corresponding variation of the baryon-to-photon ratio: Δη/η ≲ 10 -5 . It has been shown that the variation of the baryon-to-photon ratio caused by the annihilation of the dark matter particles is negligible during the cosmological epochs from Big Bang nucleosynthesis to the present epoch. (paper)

Thermodynamic evolution far from equilibrium

Science.gov (United States)

Khantuleva, Tatiana A.

2018-05-01

The presented model of thermodynamic evolution of an open system far from equilibrium is based on the modern results of nonequilibrium statistical mechanics, the nonlocal theory of nonequilibrium transport developed by the author and the Speed Gradient principle introduced in the theory of adaptive control. Transition to a description of the system internal structure evolution at the mesoscopic level allows a new insight at the stability problem of non-equilibrium processes. The new model is used in a number of specific tasks.

SYSTEMATIC UNCERTAINTIES IN BLACK HOLE MASSES DETERMINED FROM SINGLE-EPOCH SPECTRA

International Nuclear Information System (INIS)

Denney, Kelly D.; Peterson, Bradley M.; Dietrich, Matthias; Bentz, Misty C.; Vestergaard, Marianne

2009-01-01

We explore the nature of systematic errors that can arise in measurement of black hole masses from single-epoch (SE) spectra of active galactic nuclei (AGNs) by utilizing the many epochs available for NGC 5548 and PG1229+204 from reverberation mapping (RM) databases. In particular, we examine systematics due to AGN variability, contamination due to constant spectral components (i.e., narrow lines and host galaxy flux), data quality (i.e., signal-to-noise ratio (S/N)), and blending of spectral features. We investigate the effect that each of these systematics has on the precision and accuracy of SE masses calculated from two commonly used line width measures by comparing these results to recent RM studies. We calculate masses by characterizing the broad Hβ emission line by both the full width at half maximum and the line dispersion, and demonstrate the importance of removing narrow emission-line components and host starlight. We find that the reliability of line width measurements rapidly decreases for S/N lower than ∼ 10-20 (per pixel), and that fitting the line profiles instead of direct measurement of the data does not mitigate this problem but can, in fact, introduce systematic errors. We also conclude that a full spectral decomposition to deblend the AGN and galaxy spectral features is unnecessary, except to judge the contribution of the host galaxy to the luminosity and to deblend any emission lines that may inhibit accurate line width measurements. Finally, we present an error budget which summarizes the minimum observable uncertainties as well as the amount of additional scatter and/or systematic offset that can be expected from the individual sources of error investigated. In particular, we find that the minimum observable uncertainty in SE mass estimates due to variability is ∼ 20 pixel -1 ) spectra.

The Transcriptome of Nacobbus aberrans Reveals Insights into the Evolution of Sedentary Endoparasitism in Plant-Parasitic Nematodes

Science.gov (United States)

Eves-van den Akker, Sebastian; Lilley, Catherine J.; Danchin, Etienne G. J.; Rancurel, Corinne; Cock, Peter J. A.; Urwin, Peter E.; Jones, John T.

2014-01-01

Within the phylum Nematoda, plant-parasitism is hypothesized to have arisen independently on at least four occasions. The most economically damaging plant-parasitic nematode species, and consequently the most widely studied, are those that feed as they migrate destructively through host roots causing necrotic lesions (migratory endoparasites) and those that modify host root tissue to create a nutrient sink from which they feed (sedentary endoparasites). The false root-knot nematode Nacobbus aberrans is the only known species to have both migratory endoparasitic and sedentary endoparasitic stages within its life cycle. Moreover, its sedentary stage appears to have characteristics of both the root-knot and the cyst nematodes. We present the first large-scale genetic resource of any false-root knot nematode species. We use RNAseq to describe relative abundance changes in all expressed genes across the life cycle to provide interesting insights into the biology of this nematode as it transitions between modes of parasitism. A multigene phylogenetic analysis of N. aberrans with respect to plant-parasitic nematodes of all groups confirms its proximity to both cyst and root-knot nematodes. We present a transcriptome-wide analysis of both lateral gene transfer events and the effector complement. Comparing parasitism genes of typical root-knot and cyst nematodes to those of N. aberrans has revealed interesting similarities. Importantly, genes that were believed to be either cyst nematode, or root-knot nematode, “specific” have both been identified in N. aberrans. Our results provide insights into the characteristics of a common ancestor and the evolution of sedentary endoparasitism of plants by nematodes. PMID:25123114

Integrative studies of cultural evolution: crossing disciplinary boundaries to produce new insights.

Science.gov (United States)

Kolodny, Oren; Feldman, Marcus W; Creanza, Nicole

2018-04-05

Culture evolves according to dynamics on multiple temporal scales, from individuals' minute-by-minute behaviour to millennia of cultural accumulation that give rise to population-level differences. These dynamics act on a range of entities-including behavioural sequences, ideas and artefacts as well as individuals, populations and whole species-and involve mechanisms at multiple levels, from neurons in brains to inter-population interactions. Studying such complex phenomena requires an integration of perspectives from a diverse array of fields, as well as bridging gaps between traditionally disparate areas of study. In this article, which also serves as an introduction to the current special issue, we highlight some specific respects in which the study of cultural evolution has benefited and should continue to benefit from an integrative approach. We showcase a number of pioneering studies of cultural evolution that bring together numerous disciplines. These studies illustrate the value of perspectives from different fields for understanding cultural evolution, such as cognitive science and neuroanatomy, behavioural ecology, population dynamics, and evolutionary genetics. They also underscore the importance of understanding cultural processes when interpreting research about human genetics, neuroscience, behaviour and evolution.This article is part of the theme issue 'Bridging cultural gaps: interdisciplinary studies in human cultural evolution'. © 2018 The Author(s).

Multiepoch Spectropolarimetry of SN 2011fe

International Nuclear Information System (INIS)

Milne, Peter A.; Williams, G. Grant; Smith, Paul S.; Smith, Nathan; Jannuzi, Buell T.; Green, E. M.; Porter, Amber; Leising, Mark D.

2017-01-01

We present multiple spectropolarimetric observations of the nearby Type Ia supernova (SN) 2011fe in M101, obtained before, during, and after the time of maximum apparent visual brightness. The excellent time coverage of our spectropolarimetry has allowed better monitoring of the evolution of polarization features than is typical, which has allowed us new insight into the nature of normal SNe Ia. SN 2011fe exhibits time-dependent polarization in both the continuum and strong absorption lines. At early epochs, red wavelengths exhibit a degree of continuum polarization of up to 0.4%, likely indicative of a mild asymmetry in the electron-scattering photosphere. This behavior is more common in subluminous SNe Ia than in normal events, such as SN 2011fe. The degree of polarization across a collection of absorption lines varies dramatically from epoch to epoch. During the earliest epoch, a λ 4600–5000 Å complex of absorption lines shows enhanced polarization at a different position angle than the continuum. We explore the origin of these features, presenting a few possible interpretations, without arriving at a single favored ion. During two epochs near maximum, the dominant polarization feature is associated with the Si ii λ 6355 Å absorption line. This is common for SNe Ia, but for SN 2011fe the polarization of this feature increases after maximum light, whereas for other SNe Ia, that polarization feature was strongest before maximum light.

Multiepoch Spectropolarimetry of SN 2011fe

Energy Technology Data Exchange (ETDEWEB)

Milne, Peter A.; Williams, G. Grant; Smith, Paul S.; Smith, Nathan; Jannuzi, Buell T.; Green, E. M. [University of Arizona, Steward Observatory, 933 N. Cherry Avenue, Tucson, AZ 85721 (United States); Porter, Amber; Leising, Mark D. [118 Kinard Laboratory, Clemson University, Clemson, SC 29634 (United States)

2017-01-20

We present multiple spectropolarimetric observations of the nearby Type Ia supernova (SN) 2011fe in M101, obtained before, during, and after the time of maximum apparent visual brightness. The excellent time coverage of our spectropolarimetry has allowed better monitoring of the evolution of polarization features than is typical, which has allowed us new insight into the nature of normal SNe Ia. SN 2011fe exhibits time-dependent polarization in both the continuum and strong absorption lines. At early epochs, red wavelengths exhibit a degree of continuum polarization of up to 0.4%, likely indicative of a mild asymmetry in the electron-scattering photosphere. This behavior is more common in subluminous SNe Ia than in normal events, such as SN 2011fe. The degree of polarization across a collection of absorption lines varies dramatically from epoch to epoch. During the earliest epoch, a λ 4600–5000 Å complex of absorption lines shows enhanced polarization at a different position angle than the continuum. We explore the origin of these features, presenting a few possible interpretations, without arriving at a single favored ion. During two epochs near maximum, the dominant polarization feature is associated with the Si ii λ 6355 Å absorption line. This is common for SNe Ia, but for SN 2011fe the polarization of this feature increases after maximum light, whereas for other SNe Ia, that polarization feature was strongest before maximum light.

Kinematic evolution of fold and thrust belts. Insights from experimental modeling

International Nuclear Information System (INIS)

Ueta, Keiichi

2011-01-01

Physical experiments were performed to gain a better understanding on the kinematic evolution of fold and thrust belts. The present study focuses on deformation of sedimentary cover caused by thrust and reverse movements along the basement fault. Our physical models comprise dry quartz sand representing brittle sedimentary rock and viscous silicone polymer representing overpressured mudstone. Computerized X-ray tomography was applied to the experiments to analyze the kinematic evolution of fold and thrust belts. In the sand models, the width of deformation zone above thrust was wider than that above reverse fault, because back thrust developed on the hanging wall of reverse fault. Within the physical models composed of dry sand and silicone polymer, minor folds and thrusts with minor displacement developed on the footwall of the major monoclinal flexure. These results compare well with the geometry and kinematic evolution of the fold and thrust belts in Japan. (author)

Modeling the Radio Foreground for Detection of CMB Spectral Distortions from the Cosmic Dawn and the Epoch of Reionization

Energy Technology Data Exchange (ETDEWEB)

Sathyanarayana Rao, Mayuri; Subrahmanyan, Ravi; Shankar, N Udaya [Raman Research Institute, C V Raman Avenue, Sadashivanagar, Bangalore 560080 (India); Chluba, Jens, E-mail: mayuris@rri.res.in [Jodrell Bank Centre for Astrophysics, University of Manchester, Oxford Road, M13 9PL (United Kingdom)

2017-05-01

Cosmic baryon evolution during the Cosmic Dawn and Reionization results in redshifted 21-cm spectral distortions in the cosmic microwave background (CMB). These encode information about the nature and timing of first sources over redshifts 30–6 and appear at meter wavelengths as a tiny CMB distortion along with the Galactic and extragalactic radio sky, which is orders of magnitude brighter. Therefore, detection requires precise methods to model foregrounds. We present a method of foreground fitting using maximally smooth (MS) functions. We demonstrate the usefulness of MS functions over traditionally used polynomials to separate foregrounds from the Epoch of Reionization (EoR) signal. We also examine the level of spectral complexity in plausible foregrounds using GMOSS, a physically motivated model of the radio sky, and find that they are indeed smooth and can be modeled by MS functions to levels sufficient to discern the vanilla model of the EoR signal. We show that MS functions are loss resistant and robustly preserve EoR signal strength and turning points in the residuals. Finally, we demonstrate that in using a well-calibrated spectral radiometer and modeling foregrounds with MS functions, the global EoR signal can be detected with a Bayesian approach with 90% confidence in 10 minutes’ integration.

Insights into bilaterian evolution from three spiralian genomes

Energy Technology Data Exchange (ETDEWEB)

Simakov, Oleg; Marletaz, Ferdinand; Cho, Sung-Jin; Edsinger-Gonzales, Eric; Havlak, Paul; Hellsten, Uffe; Kuo, Dian-Han; Larsson, Tomas; Lv, Jie; Arendt, Detlev; Savage, Robert; Osoegawa, Kazutoyo; de Jong, Pieter; Grimwood, Jane; Chapman, Jarrod A.; Shapiro, Harris; Otillar, Robert P.; Terry, Astrid Y.; Boore, Jeffrey L.; Grigoriev, Igor V.; Lindberg, David R.; Seaver, Elaine C.; Weisblat, David A.; Putnam, Nicholas H.; Rokhsar, Daniel S.; Aerts, Andrea

2012-01-07

Current genomic perspectives on animal diversity neglect two prominent phyla, the molluscs and annelids, that together account for nearly one-third of known marine species and are important both ecologically and as experimental systems in classical embryology1, 2, 3. Here we describe the draft genomes of the owl limpet (Lottia gigantea), a marine polychaete (Capitella teleta) and a freshwater leech (Helobdella robusta), and compare them with other animal genomes to investigate the origin and diversification of bilaterians from a genomic perspective. We find that the genome organization, gene structure and functional content of these species are more similar to those of some invertebrate deuterostome genomes (for example, amphioxus and sea urchin) than those of other protostomes that have been sequenced to date (flies, nematodes and flatworms). The conservation of these genomic features enables us to expand the inventory of genes present in the last common bilaterian ancestor, establish the tripartite diversification of bilaterians using multiple genomic characteristics and identify ancient conserved long- and short-range genetic linkages across metazoans. Superimposed on this broadly conserved pan-bilaterian background we find examples of lineage-specific genome evolution, including varying rates of rearrangement, intron gain and loss, expansions and contractions of gene families, and the evolution of clade-specific genes that produce the unique content of each genome.

Epochality, Global Capitalism and Ecology

Directory of Open Access Journals (Sweden)

Wayne Hope

2018-05-01

Full Text Available What type of capitalism do we live in today? My answer to this question draws upon two interrelated lines of argument. Firstly, I will argue that we inhabit an epoch of global capitalism. The precursors of this kind of capitalism originated from the late nineteenth century when the development of telegraph networks, modern transport systems and world time zones provided a global template for industrialisation and Western imperialism. From about 1980 a confluence of global events and processes bought a fully-fledged global capitalism into being. These included the collapse of Fordist Keynesianism, national Keynesianism and Soviet Communism along with First, Second and Third World demarcations; the international proliferation of neo-liberal policy regimes; the growth of transnational corporations in all economic sectors; the predominance of financialisation and the reconstitution of global workforces. Secondly, I will argue that the shift from organic surface energy to underground fossil energy intertwined the time of the earth with the time of human history as nature was being instrumentalised as a resource for humanity. Understanding the capitalist relations of power involved here requires that we rethink the emergence of industrial capitalism in the historical context of a world system built upon unequal socio-ecological exchange between core and periphery. Today, global capitalism has intensified the anthropogenic feedback loops associated with CO2 emissions and climate change and universalised the organisational frameworks of profit extraction and socio-ecological destruction. I refer here to the transnational systems of fossil fuel capitalism along with their interlinkages with financialisation and advertising/commodity fetishism. From the preceding lines of argument I will briefly outline the intra-capitalist and planetary-ecological crises out of which transnational coalitions of opposition might emerge.

Evolution of Spin, Orbital, and Superorbital Modulations of 4U 0114+650

International Nuclear Information System (INIS)

Hu, Chin-Ping; Ng, C.-Y.; Chou, Yi; Lin, Lupin Chun-Che; Yen, David Chien-Chang

2017-01-01

We report a systematic analysis of the spin, orbital, and superorbital modulations of 4U 0114+650, a high-mass X-ray binary that consists of one of the slowest spinning neutron stars. Using the dynamic power spectrum, we found that the spin period varied dramatically and is anticorrelated with the long-term X-ray flux variation that can be observed using the Rossi X-ray Timing Explorer ASM, Swift BAT, and the Monitor of All-sky X-ray Image. The spin-up rate over the entire data set is consistent with previously reported values; however, the local spin-up rate is considerably higher. The corresponding local spin-up timescale is comparable to the local spin-up rate of OAO 1657−415, indicating that 4U 0114+650 could also have a transient disk. Moreover, the spin period evolution shows two ∼1000-day spin-down/random-walk epochs that appeared together with depressions of the superorbital modulation amplitude. This implies that the superorbital modulation was closely related to the presence of the accretion disk, which is not favored in the spin-down/random-walk epochs because the accretion is dominated by the direct wind accretion. The orbital period is stable during the entire time span; however, the orbital profile significantly changes with time. We found that the depth of the dip near the inferior conjunction of the companion is highly variable, which disfavors the eclipsing scenario. Moreover, the dip was less obvious during the spin-down/random-walk epochs, indicating its correlation with the accretion disk. Further monitoring in both X-ray and optical bands could reveal the establishment of the accretion disk in this system.

Evolution of Spin, Orbital, and Superorbital Modulations of 4U 0114+650

Science.gov (United States)

Hu, Chin-Ping; Chou, Yi; Ng, C.-Y.; Lin, Lupin Chun-Che; Yen, David Chien-Chang

2017-07-01

We report a systematic analysis of the spin, orbital, and superorbital modulations of 4U 0114+650, a high-mass X-ray binary that consists of one of the slowest spinning neutron stars. Using the dynamic power spectrum, we found that the spin period varied dramatically and is anticorrelated with the long-term X-ray flux variation that can be observed using the Rossi X-ray Timing Explorer ASM, Swift BAT, and the Monitor of All-sky X-ray Image. The spin-up rate over the entire data set is consistent with previously reported values; however, the local spin-up rate is considerably higher. The corresponding local spin-up timescale is comparable to the local spin-up rate of OAO 1657-415, indicating that 4U 0114+650 could also have a transient disk. Moreover, the spin period evolution shows two ˜1000-day spin-down/random-walk epochs that appeared together with depressions of the superorbital modulation amplitude. This implies that the superorbital modulation was closely related to the presence of the accretion disk, which is not favored in the spin-down/random-walk epochs because the accretion is dominated by the direct wind accretion. The orbital period is stable during the entire time span; however, the orbital profile significantly changes with time. We found that the depth of the dip near the inferior conjunction of the companion is highly variable, which disfavors the eclipsing scenario. Moreover, the dip was less obvious during the spin-down/random-walk epochs, indicating its correlation with the accretion disk. Further monitoring in both X-ray and optical bands could reveal the establishment of the accretion disk in this system.

Evolution of Spin, Orbital, and Superorbital Modulations of 4U 0114+650

Energy Technology Data Exchange (ETDEWEB)

Hu, Chin-Ping; Ng, C.-Y. [Department of Physics, The University of Hong Kong, Pokfulam Road (Hong Kong); Chou, Yi [Graduate Institute of Astronomy, National Central University, Jhongli 32001, Taiwan (China); Lin, Lupin Chun-Che [Institute of Astronomy and Astrophysics, Academia Sinica, Taiwan (China); Yen, David Chien-Chang, E-mail: cphu@hku.hk [Department of Mathematics, Fu Jen Catholic University, New Taipei City 24205, Taiwan (China)

2017-07-20

We report a systematic analysis of the spin, orbital, and superorbital modulations of 4U 0114+650, a high-mass X-ray binary that consists of one of the slowest spinning neutron stars. Using the dynamic power spectrum, we found that the spin period varied dramatically and is anticorrelated with the long-term X-ray flux variation that can be observed using the Rossi X-ray Timing Explorer ASM, Swift BAT, and the Monitor of All-sky X-ray Image. The spin-up rate over the entire data set is consistent with previously reported values; however, the local spin-up rate is considerably higher. The corresponding local spin-up timescale is comparable to the local spin-up rate of OAO 1657−415, indicating that 4U 0114+650 could also have a transient disk. Moreover, the spin period evolution shows two ∼1000-day spin-down/random-walk epochs that appeared together with depressions of the superorbital modulation amplitude. This implies that the superorbital modulation was closely related to the presence of the accretion disk, which is not favored in the spin-down/random-walk epochs because the accretion is dominated by the direct wind accretion. The orbital period is stable during the entire time span; however, the orbital profile significantly changes with time. We found that the depth of the dip near the inferior conjunction of the companion is highly variable, which disfavors the eclipsing scenario. Moreover, the dip was less obvious during the spin-down/random-walk epochs, indicating its correlation with the accretion disk. Further monitoring in both X-ray and optical bands could reveal the establishment of the accretion disk in this system.

Centromeric DNA characterization in the model grass Brachypodium distachyon provides insights on the evolution of the genus.

Science.gov (United States)

Li, Yinjia; Zuo, Sheng; Zhang, Zhiliang; Li, Zhanjie; Han, Jinlei; Chu, Zhaoqing; Hasterok, Robert; Wang, Kai

2018-03-01

Brachypodium distachyon is a well-established model monocot plant, and its small and compact genome has been used as an accurate reference for the much larger and often polyploid genomes of cereals such as Avena sativa (oats), Hordeum vulgare (barley) and Triticum aestivum (wheat). Centromeres are indispensable functional units of chromosomes and they play a core role in genome polyploidization events during evolution. As the Brachypodium genus contains about 20 species that differ significantly in terms of their basic chromosome numbers, genome size, ploidy levels and life strategies, studying their centromeres may provide important insight into the structure and evolution of the genome in this interesting and important genus. In this study, we isolated the centromeric DNA of the B. distachyon reference line Bd21 and characterized its composition via the chromatin immunoprecipitation of the nucleosomes that contain the centromere-specific histone CENH3. We revealed that the centromeres of Bd21 have the features of typical multicellular eukaryotic centromeres. Strikingly, these centromeres contain relatively few centromeric satellite DNAs; in particular, the centromere of chromosome 5 (Bd5) consists of only ~40 kb. Moreover, the centromeric retrotransposons in B. distachyon (CRBds) are evolutionarily young. These transposable elements are located both within and adjacent to the CENH3 binding domains, and have similar compositions. Moreover, based on the presence of CRBds in the centromeres, the species in this study can be grouped into two distinct lineages. This may provide new evidence regarding the phylogenetic relationships within the Brachypodium genus. © 2018 The Authors The Plant Journal © 2018 John Wiley & Sons Ltd.

A dusty, normal galaxy in the epoch of reionization

DEFF Research Database (Denmark)

Watson, Darach; Christensen, Lise; Knudsen, Kirsten Kraiberg

2015-01-01

Candidates for the modest galaxies that formed most of the stars in the early universe, at redshifts $z > 7$, have been found in large numbers with extremely deep restframe-UV imaging. But it has proved difficult for existing spectrographs to characterise them in the UV. The detailed properties...... of these galaxies could be measured from dust and cool gas emission at far-infrared wavelengths if the galaxies have become sufficiently enriched in dust and metals. So far, however, the most distant UV-selected galaxy detected in dust emission is only at $z = 3.25$, and recent results have cast doubt on whether...... dust and molecules can be found in typical galaxies at this early epoch. Here we report thermal dust emission from an archetypal early universe star-forming galaxy, A1689-zD1. We detect its stellar continuum in spectroscopy and determine its redshift to be $z = 7.5\\pm0.2$ from a spectroscopic detection...

The “Anthropocene” epoch: Scientific decision or political statement?

Science.gov (United States)

Finney, Stanley C.; Edwards, Lucy E.

2016-01-01

The proposal for the “Anthropocene” epoch as a formal unit of the geologic time scale has received extensive attention in scientific and public media. However, most articles on the Anthropocene misrepresent the nature of the units of the International Chronostratigraphic Chart, which is produced by the International Commission on Stratigraphy (ICS) and serves as the basis for the geologic time scale. The stratigraphic record of the Anthropocene is minimal, especially with its recently proposed beginning in 1945; it is that of a human lifespan, and that definition relegates considerable anthropogenic change to a “pre-Anthropocene.” The utility of the Anthropocene requires careful consideration by its various potential users. Its concept is fundamentally different from the chronostratigraphic units that are established by ICS in that the documentation and study of the human impact on the Earth system are based more on direct human observation than on a stratigraphic record. The drive to officially recognize the Anthropocene may, in fact, be political rather than scientific.

Methylome evolution in plants.

Science.gov (United States)

Vidalis, Amaryllis; Živković, Daniel; Wardenaar, René; Roquis, David; Tellier, Aurélien; Johannes, Frank

2016-12-20

Despite major progress in dissecting the molecular pathways that control DNA methylation patterns in plants, little is known about the mechanisms that shape plant methylomes over evolutionary time. Drawing on recent intra- and interspecific epigenomic studies, we show that methylome evolution over long timescales is largely a byproduct of genomic changes. By contrast, methylome evolution over short timescales appears to be driven mainly by spontaneous epimutational events. We argue that novel methods based on analyses of the methylation site frequency spectrum (mSFS) of natural populations can provide deeper insights into the evolutionary forces that act at each timescale.

Genomic and secondary metabolite analyses of Streptomyces sp. 2AW provide insight into the evolution of the cycloheximide pathway

Directory of Open Access Journals (Sweden)

Elizabeth eStulberg

2016-05-01

Full Text Available The dearth of new antibiotics in the face of widespread antimicrobial resistance makes developing innovative strategies for discovering new antibiotics critical for the future management of infectious disease. Understanding the genetics and evolution of antibiotic producers will help guide the discovery and bioengineering of novel antibiotics. We discovered an isolate in Alaskan boreal forest soil that had broad antimicrobial activity. We elucidated the corresponding antimicrobial natural products and sequenced the genome of this isolate, designated Streptomyces sp. 2AW. This strain illustrates the chemical virtuosity typical of the Streptomyces genus, producing cycloheximide as well as two other biosynthetically unrelated antibiotics, neutramycin and hygromycin A. Combining bioinformatic and chemical analyses, we identified the gene clusters responsible for antibiotic production. Interestingly, 2AW appears dissimilar from other cycloheximide producers in that the gene encoding the polyketide synthase resides on a separate part of the chromosome from the genes responsible for tailoring cycloheximide-specific modifications. This gene arrangement and our phylogenetic analyses of the gene products suggest that 2AW holds an evolutionarily ancestral lineage of the cycloheximide pathway. Our analyses support the hypothesis that the 2AW glutaramide gene cluster is basal to the lineage wherein cycloheximide production diverged from other glutarimide antibiotics. This study illustrates the power of combining modern biochemical and genomic analyses to gain insight into the evolution of antibiotic-producing microorganisms.

THE HYDROGEN EPOCH OF REIONIZATION ARRAY DISH. I. BEAM PATTERN MEASUREMENTS AND SCIENCE IMPLICATIONS

International Nuclear Information System (INIS)

Neben, Abraham R.; Hewitt, Jacqueline N.; Ewall-Wice, Aaron; Bradley, Richard F.; DeBoer, David R.; Parsons, Aaron R.; Ali, Zaki S.; Cheng, Carina; Patra, Nipanjana; Dillon, Joshua S.; Aguirre, James E.; Kohn, Saul A.; Thyagarajan, Nithyanandan; Bowman, Judd; Jacobs, Daniel C.; Dickenson, Roger; Doolittle, Phillip; Egan, Dennis; Hedrick, Mike; Klima, Patricia J.

2016-01-01

The Hydrogen Epoch of Reionization Array (HERA) is a radio interferometer aiming to detect the power spectrum of 21 cm fluctuations from neutral hydrogen from the epoch of reionization (EOR). Drawing on lessons from the Murchison Widefield Array and the Precision Array for Probing the EOR, HERA is a hexagonal array of large (14 m diameter) dishes with suspended dipole feeds. The dish not only determines overall sensitivity, but also affects the observed frequency structure of foregrounds in the interferometer. This is the first of a series of four papers characterizing the frequency and angular response of the dish with simulations and measurements. In this paper, we focus on the angular response (i.e., power pattern), which sets the relative weighting between sky regions of high and low delay and thus apparent source frequency structure. We measure the angular response at 137 MHz using the ORBCOMM beam mapping system of Neben et al. We measure a collecting area of 93 m 2 in the optimal dish/feed configuration, implying that HERA-320 should detect the EOR power spectrum at z ∼ 9 with a signal-to-noise ratio of 12.7 using a foreground avoidance approach with a single season of observations and 74.3 using a foreground subtraction approach. Finally, we study the impact of these beam measurements on the distribution of foregrounds in Fourier space.

THE HYDROGEN EPOCH OF REIONIZATION ARRAY DISH. I. BEAM PATTERN MEASUREMENTS AND SCIENCE IMPLICATIONS

Energy Technology Data Exchange (ETDEWEB)

Neben, Abraham R.; Hewitt, Jacqueline N.; Ewall-Wice, Aaron [MIT Kavli Institute, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Bradley, Richard F. [Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA 22904 (United States); DeBoer, David R.; Parsons, Aaron R.; Ali, Zaki S.; Cheng, Carina; Patra, Nipanjana; Dillon, Joshua S. [Department of Astronomy, University of California, Berkeley, CA (United States); Aguirre, James E.; Kohn, Saul A. [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA (United States); Thyagarajan, Nithyanandan; Bowman, Judd; Jacobs, Daniel C. [Arizona State University, School of Earth and Space Exploration, Tempe, AZ 85287 (United States); Dickenson, Roger; Doolittle, Phillip; Egan, Dennis; Hedrick, Mike; Klima, Patricia J. [National Radio Astronomy Observatory, Charlottesville, VA (United States); and others

2016-08-01

The Hydrogen Epoch of Reionization Array (HERA) is a radio interferometer aiming to detect the power spectrum of 21 cm fluctuations from neutral hydrogen from the epoch of reionization (EOR). Drawing on lessons from the Murchison Widefield Array and the Precision Array for Probing the EOR, HERA is a hexagonal array of large (14 m diameter) dishes with suspended dipole feeds. The dish not only determines overall sensitivity, but also affects the observed frequency structure of foregrounds in the interferometer. This is the first of a series of four papers characterizing the frequency and angular response of the dish with simulations and measurements. In this paper, we focus on the angular response (i.e., power pattern), which sets the relative weighting between sky regions of high and low delay and thus apparent source frequency structure. We measure the angular response at 137 MHz using the ORBCOMM beam mapping system of Neben et al. We measure a collecting area of 93 m{sup 2} in the optimal dish/feed configuration, implying that HERA-320 should detect the EOR power spectrum at z ∼ 9 with a signal-to-noise ratio of 12.7 using a foreground avoidance approach with a single season of observations and 74.3 using a foreground subtraction approach. Finally, we study the impact of these beam measurements on the distribution of foregrounds in Fourier space.

GALAXY DOWNSIZING AND THE REDSHIFT EVOLUTION OF OXYGEN AND NITROGEN ABUNDANCES: ORIGIN OF THE SCATTER IN THE N/H-O/H DIAGRAM

International Nuclear Information System (INIS)

Pilyugin, Leonid S.; Thuan, Trinh X.

2011-01-01

The oxygen and nitrogen abundance evolutions with redshift of emission-line galaxies in the Sloan Digital Sky Survey are considered for four intervals of galaxy stellar masses, ranging from 10 11.3 M sun to 10 10.2 M sun . We have measured their line fluxes and derived the O and N abundances using recent calibrations. The evolution of O and N abundances with redshift clearly shows the galaxy downsizing effect, where enrichment (and hence star formation) ceases in high-mass galaxies at earlier times and shifts to lower-mass galaxies at later epochs. The origin of the scatter in the N/H-O/H diagram has been examined. The most massive galaxies, where O and N enrichment and star formation have already stopped, occupy a narrow band in the N/H-O/H diagram, defining an upper envelope. The less massive galaxies which are still undergoing star formation at the current epoch are shifted downward, toward lower N/H values in the N/H-O/H diagram. This downward shift is caused by the time delay between N and O enrichment. This time delay together with the different star formation histories in galaxies is responsible for the large scatter in the N/H-O/H diagram.

End-of-treatment and serial PET imaging in primary mediastinal B-cell lymphoma following dose-adjusted-EPOCH-R: A paradigm shift in clinical decision making.

Science.gov (United States)

Melani, Christopher; Advani, Ranjana; Roschewski, Mark; Walters, Kelsey M; Chen, Clara C; Baratto, Lucia; Ahlman, Mark A; Miljkovic, Milos D; Steinberg, Seth M; Lam, Jessica; Shovlin, Margaret; Dunleavy, Kieron; Pittaluga, Stefania; Jaffe, Elaine S; Wilson, Wyndham H

2018-05-10

Dose-adjusted-EPOCH-R obviates the need for radiotherapy in most patients with primary mediastinal B-cell lymphoma. End-of-treatment PET, however, does not accurately identify patients at risk of treatment failure, thereby confounding clinical decision making. To define the role of PET in primary mediastinal B-cell lymphoma following dose-adjusted-EPOCH-R, we extended enrollment and follow-up on our published phase II trial and independent series. Ninety-three patients received dose-adjusted-EPOCH-R without radiotherapy. End-of-treatment PET was performed in 80 patients, of whom 57 received 144 serial scans. One nuclear medicine physician from each institution blindly reviewed all scans from their respective institution. End-of-treatment PET was negative (Deauville 1-3) in 55 (69%) patients with one treatment failure (8-year event-free and overall survival of 96.0% and 97.7%). Among 25 (31%) patients with a positive (Deauville 4-5) end-of-treatment PET, there were 5 (20%) treatment failures (8-year event-free and overall survival of 71.1% and 84.3%). Linear regression analysis of serial scans showed a significant decrease in SUVmax in positive end-of-treatment PET non-progressors compared to an increase in treatment failures. Among 6 treatment failures, the median end-of-treatment SUVmax was 15.4 (range, 1.9-21.3) and 4 achieved long-term remission with salvage therapy. Virtually all patients with a negative end-of-treatment PET following dose-adjusted-EPOCH-R achieved durable remissions and should not receive radiotherapy. Among patients with a positive end-of-treatment PET, only 5/25 (20%) had treatment-failure. Serial PET imaging distinguished end-of-treatment PET positive patients without treatment failure, thereby reducing unnecessary radiotherapy by 80%, and should be considered in all patients with an initial positive PET following dose-adjusted-EPOCH-R (NCT00001337). Copyright © 2018, Ferrata Storti Foundation.

New insights on the geological evolution of the continental margin of Southeastern Brazil derived from zircon and apatite (U-Th-Sm)/He and fission-track data

Science.gov (United States)

Krob, Florian; Stippich, Christian; Glasmacher, Ulrich A.; Hackspacher, Peter

2017-04-01

New insights on the geological evolution of the continental margin of Southeastern Brazil derived from zircon and apatite (U-Th-Sm)/He and fission-track data Krob, F.C.1, Stippich, C. 1, Glasmacher, U.A.1, Hackspacher, P.C.2 (1) Institute of Earth Sciences, Research Group Thermochronology and Archaeometry, Heidelberg University, INF 234, 69120, Heidelberg, Germany (2) Instituto de Geociências e Ciências Exatas, Universidade Estadual Paulista, Av. 24-A, 1515 Rio Claro, SP, 13506-900, Brazil Passive continental margins are important geoarchives related to mantle dynamics, the breakup of continents, lithospheric dynamics, and other processes. The main concern yields the quantifying long-term lithospheric evolution of the continental margin between São Paulo and Laguna in southeastern Brazil since the Neoproterozoic. We put special emphasis on the reactivation of old fracture zones running into the continent and their constrains on the landscape evolution. In this contribution, we represent already consisting thermochronological data attained by fission-track and (U-Th-Sm)/He analysis on apatites and zircons. The zircon fission-track ages range between 108.4 (15.0) and 539.9 (68.4) Ma, the zircon (U-Th-Sm)/He ages between 72.9 (5.8) and 427.6 (1.8) Ma whereas the apatite fission-track ages range between 40.0 (5.3) and 134.7 (8.0) Ma, and the apatite (U-Th-Sm)/He ages between 32.1 (1.52) and 92.0 (1.86) Ma. These thermochronological ages from metamorphic, sedimentary and intrusive rocks show six distinct blocks (Laguna, Florianópolis, Curitiba, Ilha Comprida, Peruibe and Santos) with different evolution cut by old fracture zones. Furthermore, models of time-temperature evolution illustrate the differences in Pre- to post-rift exhumation histories of these blocks. The presented data will provide an insight into the complex exhumation history of the continental margin based on the existing literature data on the evolution of the Paraná basin in Brazil and the latest

BRIGHTEST CLUSTER GALAXIES AT THE PRESENT EPOCH

Energy Technology Data Exchange (ETDEWEB)

Lauer, Tod R. [National Optical Astronomy Observatory, P.O. Box 26732, Tucson, AZ 85726 (United States); Postman, Marc [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Strauss, Michael A.; Graves, Genevieve J.; Chisari, Nora E. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States)

2014-12-20

We have obtained photometry and spectroscopy of 433 z ≤ 0.08 brightest cluster galaxies (BCGs) in a full-sky survey of Abell clusters to construct a BCG sample suitable for probing deviations from the local Hubble flow. The BCG Hubble diagram over 0 < z < 0.08 is consistent to within 2% of the Hubble relation specified by a Ω {sub m} = 0.3, Λ = 0.7 cosmology. This sample allows us to explore the structural and photometric properties of BCGs at the present epoch, their location in their hosting galaxy clusters, and the effects of the cluster environment on their structure and evolution. We revisit the L{sub m} -α relation for BCGs, which uses α, the log-slope of the BCG photometric curve of growth, to predict the metric luminosity in an aperture with 14.3 kpc radius, L{sub m} , for use as a distance indicator. Residuals in the relation are 0.27 mag rms. We measure central stellar velocity dispersions, σ, of the BCGs, finding the Faber-Jackson relation to flatten as the metric aperture grows to include an increasing fraction of the total BCG luminosity. A three-parameter ''metric plane'' relation using α and σ together gives the best prediction of L{sub m} , with 0.21 mag residuals. The distribution of projected spatial offsets, r{sub x} of BCGs from the X-ray-defined cluster center is a steep γ = –2.33 power law over 1 < r{sub x} < 10{sup 3} kpc. The median offset is ∼10 kpc, but ∼15% of the BCGs have r{sub x} > 100 kpc. The absolute cluster-dispersion normalized BCG peculiar velocity |ΔV {sub 1}|/σ {sub c} follows an exponential distribution with scale length 0.39 ± 0.03. Both L{sub m} and α increase with σ {sub c}. The α parameter is further moderated by both the spatial and velocity offset from the cluster center, with larger α correlated with the proximity of the BCG to the cluster mean velocity or potential center. At the same time, position in the cluster has little effect on L{sub m} . Likewise, residuals from

The 21-cm Signal from the cosmological epoch of recombination

Energy Technology Data Exchange (ETDEWEB)

Fialkov, A. [Departement de Physique, Ecole Normale Superieure, CNRS, 24 rue Lhomond, Paris, 75005 (France); Loeb, A., E-mail: anastasia.fialkov@phys.ens.fr, E-mail: aloeb@cfa.harvard.edu [Department of Astronomy, Harvard University, 60 Garden Street, MS-51, Cambridge, MA, 02138 (United States)

2013-11-01

The redshifted 21-cm emission by neutral hydrogen offers a unique tool for mapping structure formation in the early universe in three dimensions. Here we provide the first detailed calculation of the 21-cm emission signal during and after the epoch of hydrogen recombination in the redshift range of z ∼ 500–1,100, corresponding to observed wavelengths of 100–230 meters. The 21-cm line deviates from thermal equilibrium with the cosmic microwave background (CMB) due to the excess Lyα radiation from hydrogen and helium recombinations. The resulting 21-cm signal reaches a brightness temperature of a milli-Kelvin, orders of magnitude larger than previously estimated. Its detection by a future lunar or space-based observatory could improve dramatically the statistical constraints on the cosmological initial conditions compared to existing two-dimensional maps of the CMB anisotropies.

The 21-cm Signal from the cosmological epoch of recombination

International Nuclear Information System (INIS)

Fialkov, A.; Loeb, A.

2013-01-01

The redshifted 21-cm emission by neutral hydrogen offers a unique tool for mapping structure formation in the early universe in three dimensions. Here we provide the first detailed calculation of the 21-cm emission signal during and after the epoch of hydrogen recombination in the redshift range of z ∼ 500–1,100, corresponding to observed wavelengths of 100–230 meters. The 21-cm line deviates from thermal equilibrium with the cosmic microwave background (CMB) due to the excess Lyα radiation from hydrogen and helium recombinations. The resulting 21-cm signal reaches a brightness temperature of a milli-Kelvin, orders of magnitude larger than previously estimated. Its detection by a future lunar or space-based observatory could improve dramatically the statistical constraints on the cosmological initial conditions compared to existing two-dimensional maps of the CMB anisotropies

The faint-end of galaxy luminosity functions at the Epoch of Reionization

Science.gov (United States)

Yue, B.; Castellano, M.; Ferrara, A.; Fontana, A.; Merlin, E.; Amorín, R.; Grazian, A.; Mármol-Queralto, E.; Michałowski, M. J.; Mortlock, A.; Paris, D.; Parsa, S.; Pilo, S.; Santini, P.; Di Criscienzo, M.

2018-05-01

During the Epoch of Reionization (EoR), feedback effects reduce the efficiency of star formation process in small halos or even fully quench it. The galaxy luminosity function (LF) may then turn over at the faint-end. We analyze the number counts of z > 5 galaxies observed in the fields of four Frontier Fields (FFs) clusters and obtain constraints on the LF faint-end: for the turn-over magnitude at z ~ 6, MUVT >~-13.3 for the circular velocity threshold of quenching star formation process, vc* <~ 47 km s-1. We have not yet found significant evidence of the presence of feedback effects suppressing the star formation in small galaxies.

Evolution and functional insights of different ancestral orthologous clades of chitin synthase genes in the fungal tree of life

Directory of Open Access Journals (Sweden)

Mu eLi

2016-02-01

Full Text Available Chitin synthases (CHSs are key enzymes in the biosynthesis of chitin, an important structural component of fungal cell walls that can trigger innate immune responses in host plants and animals. Members of CHS gene family perform various functions in fungal cellular processes. Previous studies focused primarily on classifying diverse CHSs into different classes, regardless of their functional diversification, or on characterizing their functions in individual fungal species. A complete and systematic comparative analysis of CHS genes based on their orthologous relationships will be valuable for elucidating the evolution and functions of different CHS genes in fungi. Here, we identified and compared members of the CHS gene family across the fungal tree of life, including 18 divergent fungal lineages. Phylogenetic analysis revealed that the fungal CHS gene family is comprised of at least 10 ancestral orthologous clades, which have undergone multiple independent duplications and losses in different fungal lineages during evolution. Interestingly, one of these CHS clades (class III was expanded in plant or animal pathogenic fungi belonging to different fungal lineages. Two clades (classes VIb and VIc identified for the first time in this study occurred mainly in plant pathogenic fungi from Sordariomycetes and Dothideomycetes. Moreover, members of classes III and VIb were specifically up-regulated during plant infection, suggesting important roles in pathogenesis. In addition, CHS-associated networks conserved among plant pathogenic fungi are involved in various biological processes, including sexual reproduction and plant infection. We also identified specificity-determining sites, many of which are located at or adjacent to important structural and functional sites that are potentially responsible for functional divergence of different CHS classes. Overall, our results provide new insights into the evolution and function of members of CHS gene

New insights into the evolutionary history of biological nitrogen fixation

Directory of Open Access Journals (Sweden)

Eric eBoyd

2013-08-01

Full Text Available Nitrogenase, which catalyzes the ATP-dependent reduction of dinitrogen (N2 to ammonia (NH3, accounts for roughly half of the bioavailable nitrogen supporting extant life. The fundamental requirement for fixed forms of nitrogen for life on Earth, both at present and in the past, has led to broad and significant interest in the origin and evolution of this fundamental biological process. One key question is whether the limited availability of fixed nitrogen was a factor in life’s origin or whether there were ample sources of fixed nitrogen produced by abiotic processes or delivered through the weathering of bolide impact materials to support this early life. If the latter, the key questions become what were the characteristics of the environment that precipitated the evolution of this oxygen sensitive process, when did this occur, and how was its subsequent evolutionary history impacted by the advent of oxygenic photosynthesis and the rise of oxygen in the Earth’s biosphere. Since the availability of fixed sources of nitrogen capable of supporting early life is difficult to glean from the geologic record, there are limited means to get direct insights into these questions. Indirect insights, however, can be gained by deep phylogenetic studies of nitrogenase structural gene products and additional gene products involved in the biosynthesis of the complex metal-containing prosthetic groups associated with this enzyme complex. Insights gained from such studies, as reviewed herein, challenge traditional models for the evolution of biological nitrogen fixation and provide the basis for the development of new conceptual models that explain the stepwise evolution of this highly complex and life sustaining process.

A Definitive Measurement of Time Dilation in the Spectral Evolution of the Moderate-Redshift Type Ia Supernova 1997ex

International Nuclear Information System (INIS)

Foley, Ryan J.; Filippenko, Alexei V.; Leonard, Douglas C.; Riess, Adam G.; Nugent, Peter; Perlmutter, Saul

2005-01-01

We have obtained high-quality Keck optical spectra at three epochs of the Type Ia supernova 1997ex, whose redshift z is 0.361. The elapsed calendar time between the first two spectra was 24.88 days, and that between the first and third spectra was 30.95 days. In an expanding universe where 1+z represents the factor by which space has expanded between the emission and detection of light, the amount of aging in the supernova rest frame should be a factor of 1/(1+z) smaller than the observed-frame aging; thus, we expect SN 1997ex to have aged 18.28 and 22.74 days between the first epoch and the second and third epochs, respectively. The quantitative method for determining the spectral-feature age of an SN Ia reveals that the corresponding elapsed times in the supernova rest frame were 16.97+/-2.75 and 18.01+/-3.14 days, respectively. This result is inconsistent with no time dilation with a significance level of 99.0 percent, providing evidence against ''tired light'' and other hypotheses in which no time dilation is expected. Moreover, the observed timescale of spectral evolution is inconsistent with that expected in the ''variable mass theory''. The result is within ∼1 of the aging expected from a universe in which redshift is produced by cosmic expansion

Global Peak in Atmospheric Radiocarbon Provides a Potential Definition for the Onset of the Anthropocene Epoch in 1965.

Science.gov (United States)

Turney, Chris S M; Palmer, Jonathan; Maslin, Mark A; Hogg, Alan; Fogwill, Christopher J; Southon, John; Fenwick, Pavla; Helle, Gerhard; Wilmshurst, Janet M; McGlone, Matt; Bronk Ramsey, Christopher; Thomas, Zoë; Lipson, Mathew; Beaven, Brent; Jones, Richard T; Andrews, Oliver; Hua, Quan

2018-02-19

Anthropogenic activity is now recognised as having profoundly and permanently altered the Earth system, suggesting we have entered a human-dominated geological epoch, the 'Anthropocene'. To formally define the onset of the Anthropocene, a synchronous global signature within geological-forming materials is required. Here we report a series of precisely-dated tree-ring records from Campbell Island (Southern Ocean) that capture peak atmospheric radiocarbon ( 14 C) resulting from Northern Hemisphere-dominated thermonuclear bomb tests during the 1950s and 1960s. The only alien tree on the island, a Sitka spruce (Picea sitchensis), allows us to seasonally-resolve Southern Hemisphere atmospheric 14 C, demonstrating the 'bomb peak' in this remote and pristine location occurred in the last-quarter of 1965 (October-December), coincident with the broader changes associated with the post-World War II 'Great Acceleration' in industrial capacity and consumption. Our findings provide a precisely-resolved potential Global Stratotype Section and Point (GSSP) or 'golden spike', marking the onset of the Anthropocene Epoch.

Aspects of gorgonopsian paleobiology and evolution: insights from the basicranium, occiput, osseous labyrinth, vasculature, and neuroanatomy

Directory of Open Access Journals (Sweden)

Ricardo Araújo

2017-04-01

Full Text Available Synapsida, the clade including therapsids and thus also mammals, is one of the two major branches of amniotes. Organismal design, with modularity as a concept, offers insights into the evolution of therapsids, a group that experienced profound anatomical transformations throughout the past 270 Ma, eventually leading to the evolution of the mammalian bauplan. However, the anatomy of some therapsid groups remains obscure. Gorgonopsian braincase anatomy is poorly known and many anatomical aspects of the brain, cranial nerves, vasculature, and osseous labyrinth, remain unclear. We analyzed two gorgonopsian specimens, GPIT/RE/7124 and GPIT/RE/7119, using propagation phase contrast synchrotron micro-computed tomography. The lack of fusion between many basicranial and occipital bones in GPIT/RE/7124, which is an immature specimen, allowed us to reconstruct its anatomy and ontogenetic sequence, in comparison with the mature GPIT/RE/7119, in great detail. We explored the braincase and rendered various skull cavities. Notably, we found that there is a separate ossification between what was previously referred to as the “parasphenoid” and the basioccipital. We reinterpreted this element as a posterior ossification of the basisphenoid: the basipostsphenoid. Moreover, we show that the previously called “parasphenoid” is in fact the co-ossification of the dermal parasphenoid and the endochondral basipresphenoid. In line with previous descriptions, the anatomy of the osseous labyrinth is rendered in detail, revealing a unique discoid morphology of the horizontal semicircular canal, rather than toroidal, probably due to architectural constraints of the ossification of the opisthotic and supraoccipital. In addition, the orientation of the horizontal semicircular canal suggests that gorgonopsians had an anteriorly tilted alert head posture. The morphology of the brain endocast is in accordance with the more reptilian endocast shape of other non

OPTICAL LINE EMISSION IN BRIGHTEST CLUSTER GALAXIES AT 0 < z < 0.6: EVIDENCE FOR A LACK OF STRONG COOL CORES 3.5 Gyr AGO?

International Nuclear Information System (INIS)

McDonald, Michael

2011-01-01

In recent years the number of known galaxy clusters beyond z ∼> 0.2 has increased drastically with the release of multiple catalogs containing >30,000 optically detected galaxy clusters over the range 0 0.3, hinting at an earlier epoch of strong cooling. We compare the evolution of emission-line nebulae to the X-ray-derived cool core (CC) fraction from the literature over the same redshift range and find overall agreement, with the exception that an upturn in the strong CC fraction is not observed at z > 0.3. The overall agreement between the evolution of CCs and optical line emission at low redshift suggests that emission-line surveys of galaxy clusters may provide an efficient method of indirectly probing the evolution of CCs and thus provide insights into the balance of heating and cooling processes at early cosmic times.

Cosmological constraints on variations of the fine structure constant at the epoch of recombination

International Nuclear Information System (INIS)

Menegoni, E; Galli, S; Archidiacono, M; Calabrese, E; Melchiorri, A

2013-01-01

In this brief work we investigate any possible variation of the fine structure constant at the epoch of recombination. The recent measurements of the Cosmic Microwave Background anisotropies at arcminute angular scales performed by the ACT and SPT experiments are probing the damping regime of Cosmic Microwave Background fluctuations. We study the role of a mechanism that could affect the shape of the Cosmic Microwave Background angular fluctuations at those scales, namely a change in the recombination process through variations in the fine structure constant α

Insights from the past: incorporating long-term landscape evolution in studies of land degradation

Science.gov (United States)

Ferro-Vazquez, Cruz; Lang, Carol; Kabora, Tabitha; Thornton-Barnett, Senna; Richer, Suzi; Gallello, Gianni; Stump, Daryl

2017-04-01

Modern approaches for assessing land degradation encompass multidisciplinary studies that have allowed a more realistic understanding of the causes and consequences of land degradation. This incipient perspective includes an increasingly important role of the studies of the past, including human history, to understand modern ecosystems and landscapes. Indeed, the current promotion of indigenous resource-use strategies as models of sustainable development was initially prompted by historical studies. However, systematic studies on whether or not indigenous management practices led to land degradation, and therefore their benefits or constraints for sustained use of natural resources, are not truly known. We argue that a joint approach combining the characterization of current soil properties with the archaeological study of traditional agricultural systems can provide insights on their sustainability. Archaeological excavation enables discerning the order in which sediments are deposited and the sequence in which structures are built. This provides data on coincident cultural and ecological change, and a long-term perspective on how agro-ecological systems operated in pre-modern states and the ways in which they resemble or differ from modern contexts. Simultaneously, these changes would have left a physical, chemical and isotopic imprint in soils that can be detected and interpreted to contribute to the production of a "usable past" (Stump, 2013). The premise is: since ancient agricultural sites may provide information on agronomic conditions after centuries to millennia of use, they can help in understanding the ways in which agroecosystems have survived, failed or adapted in the past. This will contribute to a better holistic understanding of social-ecological systems evolution by including a temporal perspective, and to a more nuanced assessment of land degradation and sustainable use. To illustrate this we present the outcome of our research at two traditional

The optical variability of SDSS quasars from multi-epoch spectroscopy. I. Results from 60 quasars with ≥ six-epoch spectra

Energy Technology Data Exchange (ETDEWEB)

Guo, Hengxiao; Gu, Minfeng, E-mail: hxguo@shao.ac.cn, E-mail: gumf@shao.ac.cn [Key Laboratory for Research in Galaxies and Cosmology, Shanghai Astronomical Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030 (China)

2014-09-01

In a sample of 60 quasars selected from the Sloan Digital Sky Survey with at least six-epoch spectroscopy, we investigate the variability of emission lines and continuum luminosity at various aspects. A strong anti-correlation between the variability and continuum luminosity at 2500 Å is found for the sample, which is consistent with previous works. In individual sources, we find that half of the sample objects follow the trend of being bluer when brighter, while the remaining half follow the redder-when-brighter (RWB) trend. Although the mechanism for RWB is unclear, the effects of host galaxy contribution due to seeing variations cannot be completely ruled out. As expected from the photoionization model, the positive correlations between the broad emission line and continuum luminosity are found in most individual sources, as well as for the whole sample. We confirm the Baldwin effect in most individual objects and the whole sample, while a negative Baldwin effect is also found in several quasars, which can be at least partly (if not all) due to the host galaxy contamination. We find positive correlations between the broad emission line luminosity and line width in most individual quasars, as well as the whole sample, implying a line base that is more variable than the line core.

Personal aggrandizement: an insight into Ben Enwonwu's privilege ...

African Journals Online (AJOL)

This paper titled Personal Aggrandizement: An Insight into Ben Enwonwu's Privilege Position in the Evolution of Nigerian Art, looks at the first trained artists. How the artists were classified by their styles either in the naturalistic, the abstract or the expressive imageries. The study examines and compares the contributions of ...

Modeling Temporal Evolution and Multiscale Structure in Networks

DEFF Research Database (Denmark)

Herlau, Tue; Mørup, Morten; Schmidt, Mikkel Nørgaard

2013-01-01

Many real-world networks exhibit both temporal evolution and multiscale structure. We propose a model for temporally correlated multifurcating hierarchies in complex networks which jointly capture both effects. We use the Gibbs fragmentation tree as prior over multifurcating trees and a change......-point model to account for the temporal evolution of each vertex. We demonstrate that our model is able to infer time-varying multiscale structure in synthetic as well as three real world time-evolving complex networks. Our modeling of the temporal evolution of hierarchies brings new insights...

A Genomic Survey of SCPP Family Genes in Fishes Provides Novel Insights into the Evolution of Fish Scales.

Science.gov (United States)

Lv, Yunyun; Kawasaki, Kazuhiko; Li, Jia; Li, Yanping; Bian, Chao; Huang, Yu; You, Xinxin; Shi, Qiong

2017-11-16

The family of secretory calcium-binding phosphoproteins (SCPPs) have been considered vital to skeletal tissue mineralization. However, most previous SCPP studies focused on phylogenetically distant animals but not on those closely related species. Here we provide novel insights into the coevolution of SCPP genes and fish scales in 10 species from Otophysi . According to their scale phenotypes, these fishes can be divided into three groups, i.e., scaled, sparsely scaled, and scaleless. We identified homologous SCPP genes in the genomes of these species and revealed an absence of some SCPP members in some genomes, suggesting an uneven evolutionary history of SCPP genes in fishes. In addition, most of these SCPP genes, with the exception of SPP1 , individually form one or two gene cluster(s) on each corresponding genome. Furthermore, we constructed phylogenetic trees using maximum likelihood method to estimate their evolution. The phylogenetic topology mostly supports two subclasses in some species, such as Cyprinus carpio , Sinocyclocheilus anshuiensis , S. grahamin , and S. rhinocerous , but not in the other examined fishes. By comparing the gene structures of recently reported candidate genes, SCPP1 and SCPP5 , for determining scale phenotypes, we found that the hypothesis is suitable for Astyanax mexicanus , but denied by S. anshuiensis , even though they are both sparsely scaled for cave adaptation. Thus, we conclude that, although different fish species display similar scale phenotypes, the underlying genetic changes however might be diverse. In summary, this paper accelerates the recognition of the SCPP family in teleosts for potential scale evolution.

Identification enhancement of auditory evoked potentials in EEG by epoch concatenation and temporal decorrelation.

Science.gov (United States)

Zavala-Fernandez, H; Orglmeister, R; Trahms, L; Sander, T H

2012-12-01

Event-related potentials (ERP) recorded by electroencephalography (EEG) are brain responses following an external stimulus, e.g., a sound or an image. They are used in fundamental cognitive research and neurological and psychiatric clinical research. ERPs are weaker than spontaneous brain activity and therefore it is difficult or even impossible to identify an ERP in the brain activity following an individual stimulus. For this reason, a blind source separation method relying on statistical information is proposed for the isolation of ERP after auditory stimulation. In this paper it is suggested to integrate epoch concatenation into the popular temporal decorrelation algorithm SOBI/TDSEP relying on time shifted correlations. With the proposed epoch concatenation temporal decorrelation (ecTD) algorithm a component representing the auditory evoked potential (AEP) is found in electroencephalographic data from an auditory stimulation experiment lasting 3min. The ecTD result is compared with the averaged AEP and it is superior to the result from the SOBI/TDSEP algorithm. Furthermore the ecTD processing leads to significant increases in the signal-to-noise ratio (shape SNR) of the AEP and reduces the computation time by 50% if compared to the SOBI/TDSEP calculation. It can be concluded that data concatenation in combination with temporal decorrelation is useful for isolating and improving the properties of an AEP especially in a short duration stimulation experiment. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

EPOCH 0013 - the impact of elevated CO{sub 2} upon the response of European forests

Energy Technology Data Exchange (ETDEWEB)

Lee, H.S.J.; Jarvis, P.G. [University of Edinburgh, Edinburgh (United Kingdom). Inst. of Ecology and Resource Management

1994-12-31

Apart from details on the EPOCH project, this paper includes information on the currently funded project under the Environment R & D programme (the likely impact of rising CO{sub 2} and temperature on European forests, 1993 & 1994) and the proposed extension of this is Environment R & D, phase II (predicting the response of European forests to global change, 1995 & 1996). Some suggestions for future work under Framework IV are also proposed. 30 refs., 14 refs., 8 tabs.

Atlas Basemaps in Web 2.0 Epoch

Science.gov (United States)

Chabaniuk, V.; Dyshlyk, O.

2016-06-01

The authors have analyzed their experience of the production of various Electronic Atlases (EA) and Atlas Information Systems (AtIS) of so-called "classical type". These EA/AtIS have been implemented in the past decade in the Web 1.0 architecture (e.g., National Atlas of Ukraine, Atlas of radioactive contamination of Ukraine, and others). One of the main distinguishing features of these atlases was their static nature - the end user could not change the content of EA/AtIS. Base maps are very important element of any EA/AtIS. In classical type EA/AtIS they were static datasets, which consisted of two parts: the topographic data of a fixed scale and data of the administrative-territorial division of Ukraine. It is important to note that the technique of topographic data production was based on the use of direct channels of topographic entity observation (such as aerial photography) for the selected scale. Changes in the information technology of the past half-decade are characterized by the advent of the "Web 2.0 epoch". Due to this, in cartography appeared such phenomena as, for example, "neo-cartography" and various mapping platforms like OpenStreetMap. These changes have forced developers of EA/AtIS to use new atlas basemaps. Our approach is described in the article. The phenomenon of neo-cartography and/or Web 2.0 cartography are analysed by authors using previously developed Conceptual framework of EA/AtIS. This framework logically explains the cartographic phenomena relations of three formations: Web 1.0, Web 1.0x1.0 and Web 2.0. Atlas basemaps of the Web 2.0 epoch are integrated information systems. We use several ways to integrate separate atlas basemaps into the information system - by building: weak integrated information system, structured system and meta-system. This integrated information system consists of several basemaps and falls under the definition of "big data". In real projects it is already used the basemaps of three strata: Conceptual

EVOLUTION IN THE H I GAS CONTENT OF GALAXY GROUPS: PRE-PROCESSING AND MASS ASSEMBLY IN THE CURRENT EPOCH

Energy Technology Data Exchange (ETDEWEB)

Hess, Kelley M. [Astrophysics, Cosmology and Gravity Centre (ACGC), Department of Astronomy, University of Cape Town, Rondebosch 7701 (South Africa); Wilcots, Eric M., E-mail: hess@ast.uct.ac.za, E-mail: ewilcots@astro.wisc.edu [Department of Astronomy, University of Wisconsin-Madison, Madison, WI 53706 (United States)

2013-11-01

We present an analysis of the neutral hydrogen (H I) content and distribution of galaxies in groups as a function of their parent dark matter halo mass. The Arecibo Legacy Fast ALFA survey α.40 data release allows us, for the first time, to study the H I properties of over 740 galaxy groups in the volume of sky common to the Sloan Digital Sky Survey (SDSS) and ALFALFA surveys. We assigned ALFALFA H I detections a group membership based on an existing magnitude/volume-limited SDSS Data Release 7 group/cluster catalog. Additionally, we assigned group ''proximity' membership to H I detected objects whose optical counterpart falls below the limiting optical magnitude—thereby not contributing substantially to the estimate of the group stellar mass, but significantly to the total group H I mass. We find that only 25% of the H I detected galaxies reside in groups or clusters, in contrast to approximately half of all optically detected galaxies. Further, we plot the relative positions of optical and H I detections in groups as a function of parent dark matter halo mass to reveal strong evidence that H I is being processed in galaxies as a result of the group environment: as optical membership increases, groups become increasingly deficient of H I rich galaxies at their center and the H I distribution of galaxies in the most massive groups starts to resemble the distribution observed in comparatively more extreme cluster environments. We find that the lowest H I mass objects lose their gas first as they are processed in the group environment, and it is evident that the infall of gas rich objects is important to the continuing growth of large scale structure at the present epoch, replenishing the neutral gas supply of groups. Finally, we compare our results to those of cosmological simulations and find that current models cannot simultaneously predict the H I selected halo occupation distribution for both low and high mass halos.

Sequential Probability Ratio Test for Collision Avoidance Maneuver Decisions Based on a Bank of Norm-Inequality-Constrained Epoch-State Filters

Science.gov (United States)

Carpenter, J. R.; Markley, F. L.; Alfriend, K. T.; Wright, C.; Arcido, J.

2011-01-01

Sequential probability ratio tests explicitly allow decision makers to incorporate false alarm and missed detection risks, and are potentially less sensitive to modeling errors than a procedure that relies solely on a probability of collision threshold. Recent work on constrained Kalman filtering has suggested an approach to formulating such a test for collision avoidance maneuver decisions: a filter bank with two norm-inequality-constrained epoch-state extended Kalman filters. One filter models 1he null hypothesis 1ha1 the miss distance is inside the combined hard body radius at the predicted time of closest approach, and one filter models the alternative hypothesis. The epoch-state filter developed for this method explicitly accounts for any process noise present in the system. The method appears to work well using a realistic example based on an upcoming highly-elliptical orbit formation flying mission.

PROBING THE EPOCH OF PRE-REIONIZATION BY CROSS-CORRELATING COSMIC MICROWAVE AND INFRARED BACKGROUND ANISOTROPIES

International Nuclear Information System (INIS)

Atrio-Barandela, F.; Kashlinsky, A.

2014-01-01

The epoch of first star formation and the state of the intergalactic medium (IGM) at that time are not directly observable with current telescopes. The radiation from those early sources is now part of the cosmic infrared background (CIB) and, as these sources ionize the gas around them, the IGM plasma would produce faint temperature anisotropies in the cosmic microwave background (CMB) via the thermal Sunyaev-Zeldovich (TSZ) effect. While these TSZ anisotropies are too faint to be detected, we show that the cross-correlation of maps of source-subtracted CIB fluctuations from Euclid, with suitably constructed microwave maps at different frequencies, can probe the physical state of the gas during reionization and test/constrain models of the early CIB sources. We identify the frequency-combined, CMB-subtracted microwave maps from space- and ground-based instruments to show that they can be cross-correlated with the forthcoming all-sky Euclid CIB maps to detect the cross-power at scales ∼5'-60' with signal-to-noise ratios (S/Ns) of up to S/N ∼ 4-8 depending on the contribution to the Thomson optical depth during those pre-reionization epochs (Δτ ≅ 0.05) and the temperature of the IGM (up to ∼10 4 K). Such a measurement would offer a new window to explore the emergence and physical properties of these first light sources

On the link between extreme floods and excess monsoon epochs in South Asia

Energy Technology Data Exchange (ETDEWEB)

Kale, Vishwas [University of Pune, Department of Geography, Pune (India)

2012-09-15

This paper provides a synoptic view of extreme monsoon floods on all the nine large rivers of South Asia and their association with the excess (above-normal) monsoon rainfall periods. Annual maximum flood series for 18 gauging stations spread over four countries (India, Pakistan, Bangladesh and Nepal) and long-term monsoon rainfall data were analyzed to ascertain whether the extreme floods were clustered in time and whether they coincided with multi-decade excess monsoon rainfall epochs at the basin level. Simple techniques, such as the Cramer's t-test, regression and Mann-Kendall (MK) tests and Hurst method were used to evaluate the trends and patterns of the flood and rainfall series. MK test reveals absence of any long-term tendency in all the series. However, the Cramer's t test and Hurst-Mandelbrot rescaled range statistic provide evidence that both rainfall and flood time series are persistent. Using the Cramer's t-test the excess monsoon epochs for each basin were identified. The excess monsoon periods for different basins were found to be highly asynchronous with respect to duration as well as the beginning and end. Three main conclusions readily emerge from the analyses. Extreme floods (>90th percentile) in South Asia show a tendency to cluster in time. About three-fourth of the extreme floods have occurred during the excess monsoon periods between {proportional_to}1840 and 2000 AD, implying a noteworthy link between the two. The frequency of large floods was higher during the post-1940 period in general and during three decades (1940s, 1950s and 1980s) in particular. (orig.)

Characteristic density contrasts in the evolution of superclusters. The case of A2142 supercluster

Science.gov (United States)

Gramann, Mirt; Einasto, Maret; Heinämäki, Pekka; Teerikorpi, Pekka; Saar, Enn; Nurmi, Pasi; Einasto, Jaan

2015-09-01

Context. The formation and evolution of the cosmic web in which galaxy superclusters are the largest relatively isolated objects is governed by a gravitational attraction of dark matter and antigravity of dark energy (cosmological constant). Aims: We study the characteristic density contrasts in the spherical collapse model for several epochs in the supercluster evolution and their dynamical state. Methods: We analysed the density contrasts for the turnaround, future collapse, and zero gravity in different ΛCDM models and applied them to study the dynamical state of the supercluster A2142 with an almost spherical main body, making it a suitable test object to apply a model that assumes sphericity. Results: We present characteristic density contrasts in the spherical collapse model for different cosmological parameters. The analysis of the supercluster A2142 shows that its high-density core has already started to collapse. The zero-gravity line outlines the outer region of the main body of the supercluster. In the course of future evolution, the supercluster may split into several collapsing systems. Conclusions: The various density contrasts presented in our study and applied to the supercluster A2142 offer a promising way to characterise the dynamical state and expected future evolution of galaxy superclusters.

Epoch making NIRS studies seen through citation trends

International Nuclear Information System (INIS)

Dan, Ippeita

2009-01-01

Near-infrared spectroscopy (NIRS) studies through citation trends are investigated of literature concerning only the brain function measurement and its methodology together with NIRS principle, technological development, present state and future view. Investigation is conducted firstly for the survey of important author name of those concerned papers in Web of Science and Google Scholar with search words of NIRS, brain and optical topography as an option. Second, >100 papers of those authors citing any of them are picked up and their papers are ranked in accordance with Web of Science citation number, of which top-nineteen are presented here. Impact and epoch making papers are reviewed with explanations of: the establishment of measuring technology of cerebral blood flow change and subsequent brain function by NIRS; development with multi-channel detection; simultaneous measurement with other imaging modalities; examination of NIRS validity; spatial analysis of NIRS; and measurement of brain function. The highest times of citation are 1,238 of the paper by F. F. Jobsis in 'Science' (1977). It should be noted that 10 of top 19 papers are those by Japanese authors. However, review articles omitted in the present literature survey are mostly described by foreign authors: an effort to systemize the concerned fields might be required in this country. (K.T.)

Elucidating dark energy with future 21 cm observations at the epoch of reionization

Energy Technology Data Exchange (ETDEWEB)

Kohri, Kazunori [The Graduate University for Advanced Studies (SOKENDAI), 1-1 Oho, Tsukuba 305-0801 (Japan); Oyama, Yoshihiko [Institute for Cosmic Ray Research, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8582 (Japan); Sekiguchi, Toyokazu [Center for Theoretical Physics of the Universe, Institute for Basic Science (IBS), 193, Munjiro, Yuseoung-gu, Daejeon 34051 (Korea, Republic of); Takahashi, Tomo, E-mail: kohri@post.kek.jp, E-mail: oyamayo@icrr.u-tokyo.ac.jp, E-mail: sekiguti@ibs.re.kr, E-mail: tomot@cc.saga-u.ac.jp [Department of Physics, Saga University, 1 Honjo, Saga 840-8502 (Japan)

2017-02-01

We investigate how precisely we can determine the nature of dark energy such as the equation of state (EoS) and its time dependence by using future observations of 21 cm fluctuations at the epoch of reionization (06.8∼< z ∼<1) such as Square Kilometre Array (SKA) and Omniscope in combination with those from cosmic microwave background, baryon acoustic oscillation, type Ia supernovae and direct measurement of the Hubble constant. We consider several parametrizations for the EoS and find that future 21 cm observations will be powerful in constraining models of dark energy, especially when its EoS varies at high redshifts.

Diversification, phylogeny and evolution of auxin response factor (ARF) family: insights gained from analyzing maize ARF genes.

Science.gov (United States)

Wang, Yijun; Deng, Dexiang; Shi, Yating; Miao, Nan; Bian, Yunlong; Yin, Zhitong

2012-03-01

Auxin response factors (ARFs), member of the plant-specific B3 DNA binding superfamily, target specifically to auxin response elements (AuxREs) in promoters of primary auxin-responsive genes and heterodimerize with Aux/IAA proteins in auxin signaling transduction cascade. In previous research, we have isolated and characterized maize Aux/IAA genes in whole-genome scale. Here, we report the comprehensive analysis of ARF genes in maize. A total of 36 ARF genes were identified and validated from the B73 maize genome through an iterative strategy. Thirty-six maize ARF genes are distributed in all maize chromosomes except chromosome 7. Maize ARF genes expansion is mainly due to recent segmental duplications. Maize ARF proteins share one B3 DNA binding domain which consists of seven-stranded β sheets and two short α helixes. Twelve maize ARFs with glutamine-rich middle regions could be as activators in modulating expression of auxin-responsive genes. Eleven maize ARF proteins are lack of homo- and heterodimerization domains. Putative cis-elements involved in phytohormones and light signaling responses, biotic and abiotic stress adaption locate in promoters of maize ARF genes. Expression patterns vary greatly between clades and sister pairs of maize ARF genes. The B3 DNA binding and auxin response factor domains of maize ARF proteins are primarily subjected to negative selection during selective sweep. The mixed selective forces drive the diversification and evolution of genomic regions outside of B3 and ARF domains. Additionally, the dicot-specific proliferation of ARF genes was detected. Comparative genomics analysis indicated that maize, sorghum and rice duplicate chromosomal blocks containing ARF homologs are highly syntenic. This study provides insights into the distribution, phylogeny and evolution of ARF gene family.

Basic Geomagnetic Network of the Republic of Croatia 2004 – 2012, with Geomagnetic Field Maps for 2009.5 epoch

Directory of Open Access Journals (Sweden)

Mario Brkić

2013-12-01

Full Text Available After more than half a century, scientific book Basic Geomagnetic Network of the Republic of Croatia 2004 – 2012, with Geomagnetic Field Maps for 2009.5 epoch describes the recent geomagnetic field on Croatian territory. A review of research in the past decade as well as the original solutions makes the book a document of contribution to geodesy and geomagnetism in Croatia.The book’s introduction gives an overview of two centuries of history and the strategic, security, economic and scientific significance of knowing the geomagnetic field on the Croatian territory. All the activities related to the updating of the geomagnetic information, which took place in the last decade, signified a big step toward the countries where geomagnetic survey is a mature scientific and technical discipline, and a scientific contribution to understanding of the nature of the Earth's magnetism.The declination, inclination and total intensity maps (along with the normal annual changes for the epoch 2009.5 are given in the Appendix. The book Basic Geomagnetic Network of the Republic of Croatia 2004 – 2012, with Geomagnetic Field Maps for 2009.5 epoch (ISBN 978-953-293-521-9 is published by the State Geodetic Administration of the Republic of Croatia. Beside editor in chief, M. Brkić, the authors are: E. Vujić, D. Šugar, E. Jungwirth, D. Markovinović, M. Rezo, M. Pavasović, O. Bjelotomić, M. Šljivarić, M. Varga and V. Poslončec-Petrić. The book contains 48 pages and 3 maps, and is published in 200 copies. CIP record is available in digital catalogue of the National and University Library in Zagreb under number 861937.

COSMIC probes into compact binary formation and evolution

Science.gov (United States)

Breivik, Katelyn

2018-01-01

The population of compact binaries in the galaxy represents the final state of all binaries that have lived up to the present epoch. Compact binaries present a unique opportunity to probe binary evolution since many of the interactions binaries experience can be imprinted on the compact binary population. By combining binary evolution simulations with catalogs of observable compact binary systems, we can distill the dominant physical processes that govern binary star evolution, as well as predict the abundance and variety of their end products.The next decades herald a previously unseen opportunity to study compact binaries. Multi-messenger observations from telescopes across all wavelengths and gravitational-wave observatories spanning several decades of frequency will give an unprecedented view into the structure of these systems and the composition of their components. Observations will not always be coincident and in some cases may be separated by several years, providing an avenue for simulations to better constrain binary evolution models in preparation for future observations.I will present the results of three population synthesis studies of compact binary populations carried out with the Compact Object Synthesis and Monte Carlo Investigation Code (COSMIC). I will first show how binary-black-hole formation channels can be understood with LISA observations. I will then show how the population of double white dwarfs observed with LISA and Gaia could provide a detailed view of mass transfer and accretion. Finally, I will show that Gaia could discover thousands black holes in the Milky Way through astrometric observations, yielding view into black-hole astrophysics that is complementary to and independent from both X-ray and gravitational-wave astronomy.

A File Based Visualization of Software Evolution

NARCIS (Netherlands)

Voinea, S.L.; Telea, A.

2006-01-01

Software Configuration Management systems are important instruments for supporting development of large software projects. They accumulate large amounts of evolution data that can be used for process accounting and auditing. We study how visualization can help developers and managers to get insight

Current perspectives on the evolution of birds

NARCIS (Netherlands)

Ericson, P.G.P.

2008-01-01

The paper summarizes the current understanding of the evolution and diversification of birds. New insights into this field have mainly come from two fundamentally different, but complementary sources of information: the many newly discovered Mesozoic bird fossils and the wealth of genetic analyses

Phylogenetic analyses provide insights into the historical biogeography and evolution of Brachyrhaphis fishes.

Science.gov (United States)

Ingley, Spencer J; Reina, Ruth G; Bermingham, Eldredge; Johnson, Jerald B

2015-08-01

The livebearing fish genus Brachyrhaphis (Poeciliidae) has become an increasingly important model in evolution and ecology research, yet the phylogeny of this group is not well understood, nor has it been examined thoroughly using modern phylogenetic methods. Here, we present the first comprehensive phylogenetic analysis of Brachyrhaphis by using four molecular markers (3mtDNA, 1nucDNA) to infer relationships among species in this genus. We tested the validity of this genus as a monophyletic group using extensive outgroup sampling based on recent phylogenetic hypotheses of Poeciliidae. We also tested the validity of recently described species of Brachyrhaphis that are part of the B. episcopi complex in Panama. Finally, we examined the impact of historical events on diversification of Brachyrhaphis, and made predictions regarding the role of different ecological environments on evolutionary diversification where known historical events apparently fail to explain speciation. Based on our results, we reject the monophyly of Brachyrhaphis, and question the validity of two recently described species (B. hessfeldi and B. roswithae). Historical biogeography of Brachyrhaphis generally agrees with patterns found in other freshwater taxa in Lower Central America, which show that geological barriers frequently predict speciation. Specifically, we find evidence in support of an 'island' model of Lower Central American formation, which posits that the nascent isthmus was partitioned by several marine connections before linking North and South America. In some cases where historic events (e.g., vicariance) fail to explain allopatric species breaks in Brachyrhaphis, ecological processes (e.g., divergent predation environments) offer additional insight into our understanding of phylogenetic diversification in this group. Copyright © 2015 Elsevier Inc. All rights reserved.

The Evolution of Swift/BAT blazars and the origin of the MeV background

Energy Technology Data Exchange (ETDEWEB)

Ajello, M.; /SLAC /KIPAC, Menlo Park; Costamante, L.; /Stanford U., HEPL /KIPAC, Menlo Park; Sambruna, R.M.; Gehrels, N.; /NASA, Goddard; Chiang, J.; /SLAC /KIPAC, Menlo Park; Rau, A.; /Caltech; Escala, A.; /SLAC /KIPAC, Menlo Park /Cerro Calan Observ.; Greiner, J.; /Garching, Max Planck Inst., MPE; Tueller, J.; /NASA, Goddard; Wall, J.V.; /British Columbia U.; Mushotzky, R.F.; /NASA, Goddard

2009-10-17

We use 3 years of data from the Swift/BAT survey to select a complete sample of X-ray blazars above 15 keV. This sample comprises 26 Flat-Spectrum Radio Quasars (FSRQs) and 12 BL Lac objects detected over a redshift range of 0.03 < z < 4.0. We use this sample to determine, for the first time in the 15-55 keV band, the evolution of blazars. We find that, contrary to the Seyfert-like AGNs detected by BAT, the population of blazars shows strong positive evolution. This evolution is comparable to the evolution of luminous optical QSOs and luminous X-ray selected AGNs. We also find evidence for an epoch-dependence of the evolution as determined previously for radio-quiet AGNs. We interpret both these findings as a strong link between accretion and jet activity. In our sample, the FSRQs evolve strongly, while our best-fit shows that BL Lacs might not evolve at all. The blazar population accounts for 10-20% (depending on the evolution of the BL Lacs) of the Cosmic X-ray background (CXB) in the 15-55 keV band. We find that FSRQs can explain the entire CXB emission for energies above 500 keV solving the mystery of the generation of the MeV background. The evolution of luminous FSRQs shows a peak in redshift (z{sub c} = 4.3 {+-} 0.5) which is larger than the one observed in QSOs and X-ray selected AGNs. We argue that FSRQs can be used as tracers of massive elliptical galaxies in the early Universe.

Cyclotide Evolution: Insights from the Analyses of Their Precursor Sequences, Structures and Distribution in Violets (Viola

Directory of Open Access Journals (Sweden)

Sungkyu Park

2017-12-01

Full Text Available Cyclotides are a family of plant proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation. By disrupting cell membranes, the cyclotides function as host defense peptides by exhibiting insecticidal, anthelmintic, antifouling, and molluscicidal activities. In this work, we provide the first insight into the evolution of this family of plant proteins by studying the Violaceae, in particular species of the genus Viola. We discovered 157 novel precursor sequences by the transcriptomic analysis of six Viola species: V. albida var. takahashii, V. mandshurica, V. orientalis, V. verecunda, V. acuminata, and V. canadensis. By combining these precursor sequences with the phylogenetic classification of Viola, we infer the distribution of cyclotides across 63% of the species in the genus (i.e., ~380 species. Using full precursor sequences from transcriptomes, we show an evolutionary link to the structural diversity of the cyclotides, and further classify the cyclotides by sequence signatures from the non-cyclotide domain. Also, transcriptomes were compared to cyclotide expression on a peptide level determined using liquid chromatography-mass spectrometry. Furthermore, the novel cyclotides discovered were associated with the emergence of new biological functions.

Comparative transcriptional profiling provides insights into the evolution and development of the zygomorphic flower of Vicia sativa (Papilionoideae.

Directory of Open Access Journals (Sweden)

Zhipeng Liu

Full Text Available BACKGROUND: Vicia sativa (the common vetch possesses a predominant zygomorphic flower and belongs to the subfamily Papilionoideae, which is related to Arabidopsis thaliana in the eurosid II clade of the core eudicots. Each vetch flower consists of 21 concentrically arranged organs: the outermost five sepals, then five petals and ten stamens, and a single carpel in the center. METHODOLOGY/PRINCIPAL FINDINGS: We explored the floral transcriptome to examine a genome-scale genetic model of the zygomorphic flower of vetch. mRNA was obtained from an equal mixture of six floral organs, leaves and roots. De novo assembly of the vetch transcriptome using Illumina paired-end technology produced 71,553 unigenes with an average length of 511 bp. We then compared the expression changes in the 71,553 unigenes in the eight independent organs through RNA-Seq Quantification analysis. We predominantly analyzed gene expression patterns specific to each floral organ and combinations of floral organs that corresponded to the traditional ABC model domains. Comparative analyses were performed in the floral transcriptomes of vetch and Arabidopsis, and genomes of vetch and Medicago truncatula. CONCLUSIONS/SIGNIFICANCE: Our comparative analysis of vetch and Arabidopsis showed that the vetch flowers conform to a strict ABC model. We analyzed the evolution and expression of the TCP gene family in vetch at a whole-genome level, and several unigenes specific to three different vetch petals, which might offer some clues toward elucidating the molecular mechanisms underlying floral zygomorphy. Our results provide the first insights into the genome-scale molecular regulatory network that controls the evolution and development of the zygomorphic flower in Papilionoideae.

EVOLUTION OF THE MASS-METALLICITY RELATIONS IN PASSIVE AND STAR-FORMING GALAXIES FROM SPH-COSMOLOGICAL SIMULATIONS

International Nuclear Information System (INIS)

Romeo Velonà, A. D.; Gavignaud, I.; Meza, A.; Sommer-Larsen, J.; Napolitano, N. R.; Antonuccio-Delogu, V.; Cielo, S.

2013-01-01

We present results from SPH-cosmological simulations, including self-consistent modeling of supernova feedback and chemical evolution, of galaxies belonging to two clusters and 12 groups. We reproduce the mass-metallicity (ZM) relation of galaxies classified in two samples according to their star-forming (SF) activity, as parameterized by their specific star formation rate (sSFR), across a redshift range up to z = 2. The overall ZM relation for the composite population evolves according to a redshift-dependent quadratic functional form that is consistent with other empirical estimates, provided that the highest mass bin of the brightest central galaxies is excluded. Its slope shows irrelevant evolution in the passive sample, being steeper in groups than in clusters. However, the subsample of high-mass passive galaxies only is characterized by a steep increase of the slope with redshift, from which it can be inferred that the bulk of the slope evolution of the ZM relation is driven by the more massive passive objects. The scatter of the passive sample is dominated by low-mass galaxies at all redshifts and keeps constant over cosmic times. The mean metallicity is highest in cluster cores and lowest in normal groups, following the same environmental sequence as that previously found in the red sequence building. The ZM relation for the SF sample reveals an increasing scatter with redshift, indicating that it is still being built at early epochs. The SF galaxies make up a tight sequence in the SFR-M * plane at high redshift, whose scatter increases with time alongside the consolidation of the passive sequence. We also confirm the anti-correlation between sSFR and stellar mass, pointing at a key role of the former in determining the galaxy downsizing, as the most significant means of diagnostics of the star formation efficiency. Likewise, an anti-correlation between sSFR and metallicity can be established for the SF galaxies, while on the contrary more active galaxies

Insights into highly improved solar-driven photocatalytic oxygen evolution over integrated Ag3PO4/MoS2 heterostructures

Science.gov (United States)

Cui, Xingkai; Yang, Xiaofei; Xian, Xiaozhai; Tian, Lin; Tang, Hua; Liu, Qinqin

2018-04-01

Oxygen evolution has been considered as the rate-determining step in photocatalytic water splitting due to its sluggish four-electron half-reaction rate, the development of oxygen-evolving photocatalysts with well-defined morphologies and superior interfacial contact is highly important for achieving high-performance solar water splitting. Herein, we report the fabrication of Ag3PO4/MoS2 nanocomposites and, for the first time, their use in photocatalytic water splitting into oxygen under LED light illumination. Ag3PO4 nanoparticles were found to be anchored evenly on the surface of MoS2 nanosheets, confirming an efficient hybridization of two semiconductor materials. A maximum oxygen-generating rate of 201.6 mol L-1 g-1 h-1 was determined when 200 mg MoS2 nanosheets were incorporated into Ag3PO4 nanoparticles, which is around 5 times higher than that of bulk Ag3PO4. Obvious enhancements in light-harvesting property, as well as electron-hole separation and charge transportation are revealed by the combination of different characterizations. ESR analysis verified that more active oxygen-containing radicals generate over illuminated Ag3PO4/MoS2 composite photocatalysts rather than irradiated Ag3PO4. The improvement in oxygen evolution performance of Ag3PO4/MoS2 composite photocatalysts is ascribed to wide spectra response in the visible-light region, more efficient charge separation and enhanced oxidation capacity in the valence band (VB). This study provides new insights into the design and development of novel composite photocatalytic materials for solar-to-fuel conversion.

Evolution of the 21 cm signal throughout cosmic history

International Nuclear Information System (INIS)

Pritchard, Jonathan R.; Loeb, Abraham

2008-01-01

The potential use of the redshifted 21 cm line from neutral hydrogen for probing the epoch of reionization is motivating the construction of several low-frequency interferometers. There is also much interest in the possibility of constraining the initial conditions from inflation and the nature of the dark matter and dark energy by probing the power spectrum of density perturbations in three dimensions and on smaller scales than probed by the microwave background anisotropies. Theoretical understanding of the 21 cm signal has been fragmented into different regimes of physical interest. In this paper, we make the first attempt to describe the full redshift evolution of the 21 cm signal between 0 or approx. 25 before the first galaxies had formed, or to z < or approx. 6 when the residual pockets of hydrogen trace large-scale structure.

Divergent Geophysical Evolution of Vesta and Ceres

Science.gov (United States)

Raymond, C. A.; Ermakov, A.; Castillo, J. C.; Fu, R. R.; McSween, H. Y., Jr.; McCord, T. B.; Park, R. S.; Russell, C. T.; De Sanctis, M. C.; Jaumann, R.; Konopliv, A. S.

2017-12-01

The Dawn mission explored two massive protoplanets in the main asteroid belt, Vesta and Ceres, that are fossils from the earliest epoch of solar system formation. Dawn's data provide evidence that these bodies formed very early, within the first few million years after CAIs, yet they followed divergent evolutionary paths. Vesta formed globally homogeneous distribution of minerals across the surface indicates that Ceres' interior experienced pervasive alteration. Topography and morphology of the surface reveals smoother, apparently resurfaced areas, generally at lower elevation, and rougher areas with greater relief. Local morphology such as crater floor deposits, isolated mountains, and enigmatic bright areas indicate recently active processes on Ceres, likely driven by brine cryovolcanism. Causes of the divergent evolution of these bodies include their accretionary environment, timing of accretion and size. Acknowledgements: Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under contract to the National Aeronautics and Space Administration.

THE LICK AGN MONITORING PROJECT: RECALIBRATING SINGLE-EPOCH VIRIAL BLACK HOLE MASS ESTIMATES

Energy Technology Data Exchange (ETDEWEB)

Park, Daeseong; Woo, Jong-Hak [Astronomy Program, Department of Physics and Astronomy, Seoul National University, Seoul 151-742 (Korea, Republic of); Treu, Tommaso; Bennert, Vardha N. [Department of Physics, University of California, Santa Barbara, CA 93106 (United States); Barth, Aaron J.; Walsh, Jonelle [Department of Physics and Astronomy, 4129 Frederick Reines Hall, University of California, Irvine, CA 92697-4575 (United States); Bentz, Misty C. [Department of Physics and Astronomy, Georgia State University Atlanta, GA 30303 (United States); Canalizo, Gabriela [Department of Physics and Astronomy, University of California, Riverside, 900 University Ave., Riverside, CA 92521 (United States); Filippenko, Alexei V. [Department of Astronomy, University of California, Berkeley, CA 94720-3411 (United States); Gates, Elinor [Lick Observatory, P.O. Box 85, Mount Hamilton, CA 95140 (United States); Greene, Jenny E. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Malkan, Matthew A., E-mail: woo@astro.snu.ac.kr [Department of Physics and Astronomy, University of California, Los Angeles, CA 90024 (United States)

2012-03-01

We investigate the calibration and uncertainties of black hole (BH) mass estimates based on the single-epoch (SE) method, using homogeneous and high-quality multi-epoch spectra obtained by the Lick Active Galactic Nucleus (AGN) Monitoring Project for nine local Seyfert 1 galaxies with BH masses <10{sup 8} M{sub Sun }. By decomposing the spectra into their AGNs and stellar components, we study the variability of the SE H{beta} line width (full width at half-maximum intensity, FWHM{sub H{beta}} or dispersion, {sigma}{sub H{beta}}) and of the AGN continuum luminosity at 5100 A (L{sub 5100}). From the distribution of the 'virial products' ({proportional_to} FWHM{sub H{beta}}{sup 2} L{sup 0.5}{sub 5100} or {sigma}{sub H{beta}}{sup 2} L{sup 0.5}{sub 5100}) measured from SE spectra, we estimate the uncertainty due to the combined variability as {approx}0.05 dex (12%). This is subdominant with respect to the total uncertainty in SE mass estimates, which is dominated by uncertainties in the size-luminosity relation and virial coefficient, and is estimated to be {approx}0.46 dex (factor of {approx}3). By comparing the H{beta} line profile of the SE, mean, and root-mean-square (rms) spectra, we find that the H{beta} line is broader in the mean (and SE) spectra than in the rms spectra by {approx}0.1 dex (25%) for our sample with FWHM{sub H{beta}} <3000 km s{sup -1}. This result is at variance with larger mass BHs where the difference is typically found to be much less than 0.1 dex. To correct for this systematic difference of the H{beta} line profile, we introduce a line-width dependent virial factor, resulting in a recalibration of SE BH mass estimators for low-mass AGNs.

Insights on the evolution of mid-ocean basins: the Atlantis Basin of southern Azores

Science.gov (United States)

Alves, T.; Bouriak, S.; Volkonskaya, A.; Monteiro, J.; Ivanov, M.

2003-04-01

Single-channel seismic reflection and sidescan (OKEAN) data acquired in an unstudied region of the North Atlantic give important insights on the evolution of mid-ocean basins. Located on the eastern flank of the Mid-Atlantic Ridge, south of the Azores Islands, the study area contains more than 1,000 ms two-way travel-time of sediments with a similar seismic stratigraphy to that of ODP sites 950-952 in the Madeira Abyssal Plain. Processed thickness values correspond to a maximum thickness of about 1450 m and an average thickness of more than 500 m based on velocity data from ODP sites 950-952. The structure of the surveyed area and its location in relation to the Madeira Abyssal Plain and Mid-Atlantic Ridge indicate the existence, south of Azores, of two distinct sedimentary basins separated by major structural lineaments (Azores-Gibraltar and Atlantis Fracture Zones) and by seamount chains (Cruiser-Great Meteor Chain, Plato-Atlantis Chain). The basement of the sedimentary basins is irregular, showing multiple dome-shaped volcanic structures identical to those in the Norwegian-Greenland Sea and Madeira Abyssal Plain. However, half-graben/graben basement blocks predominate east of 30ºW underneath a moderately deformed overburden. The complex structure observed most likely reflects changes in the direction and velocity of ocean spreading plus variations in the regional thermal gradients induced by local hot spots. In parallel, some of the sub-surface structures identified next to basin-bounding Fracture Zones may have resulted from transtensional and transpressional tectonism.

New genes as drivers of phenotypic evolution

Science.gov (United States)

Chen, Sidi; Krinsky, Benjamin H.; Long, Manyuan

2014-01-01

During the course of evolution, genomes acquire novel genetic elements as sources of functional and phenotypic diversity, including new genes that originated in recent evolution. In the past few years, substantial progress has been made in understanding the evolution and phenotypic effects of new genes. In particular, an emerging picture is that new genes, despite being present in the genomes of only a subset of species, can rapidly evolve indispensable roles in fundamental biological processes, including development, reproduction, brain function and behaviour. The molecular underpinnings of how new genes can develop these roles are starting to be characterized. These recent discoveries yield fresh insights into our broad understanding of biological diversity at refined resolution. PMID:23949544

A FLUX SCALE FOR SOUTHERN HEMISPHERE 21 cm EPOCH OF REIONIZATION EXPERIMENTS

Energy Technology Data Exchange (ETDEWEB)

Jacobs, Daniel C.; Bowman, Judd [School of Earth and Space Exploration, Arizona State University, Tempe, AZ (United States); Parsons, Aaron R.; Ali, Zaki; Pober, Jonathan C. [Astronomy Department, University of California, Berkeley, CA (United States); Aguirre, James E.; Moore, David F. [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA (United States); Bradley, Richard F. [Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA (United States); Carilli, Chris L. [National Radio Astronomy Observatory, Socorro, NM (United States); DeBoer, David R.; Dexter, Matthew R.; MacMahon, Dave H. E. [Radio Astronomy Lab., University of California, Berkeley, CA (United States); Gugliucci, Nicole E.; Klima, Pat [National Radio Astronomy Observatory, Charlottesville, VA (United States); Manley, Jason R.; Walbrugh, William P. [Square Kilometer Array, South Africa Project, Cape Town (South Africa); Stefan, Irina I. [Cavendish Laboratory, Cambridge (United Kingdom)

2013-10-20

We present a catalog of spectral measurements covering a 100-200 MHz band for 32 sources, derived from observations with a 64 antenna deployment of the Donald C. Backer Precision Array for Probing the Epoch of Reionization (PAPER) in South Africa. For transit telescopes such as PAPER, calibration of the primary beam is a difficult endeavor and errors in this calibration are a major source of error in the determination of source spectra. In order to decrease our reliance on an accurate beam calibration, we focus on calibrating sources in a narrow declination range from –46° to –40°. Since sources at similar declinations follow nearly identical paths through the primary beam, this restriction greatly reduces errors associated with beam calibration, yielding a dramatic improvement in the accuracy of derived source spectra. Extrapolating from higher frequency catalogs, we derive the flux scale using a Monte Carlo fit across multiple sources that includes uncertainty from both catalog and measurement errors. Fitting spectral models to catalog data and these new PAPER measurements, we derive new flux models for Pictor A and 31 other sources at nearby declinations; 90% are found to confirm and refine a power-law model for flux density. Of particular importance is the new Pictor A flux model, which is accurate to 1.4% and shows that between 100 MHz and 2 GHz, in contrast with previous models, the spectrum of Pictor A is consistent with a single power law given by a flux at 150 MHz of 382 ± 5.4 Jy and a spectral index of –0.76 ± 0.01. This accuracy represents an order of magnitude improvement over previous measurements in this band and is limited by the uncertainty in the catalog measurements used to estimate the absolute flux scale. The simplicity and improved accuracy of Pictor A's spectrum make it an excellent calibrator in a band important for experiments seeking to measure 21 cm emission from the epoch of reionization.

Galaxy Evolution Insights from Spectral Modeling of Large Data Sets from the Sloan Digital Sky Survey

Energy Technology Data Exchange (ETDEWEB)

Hoversten, Erik A. [Johns Hopkins Univ., Baltimore, MD (United States)

2007-10-01

This thesis centers on the use of spectral modeling techniques on data from the Sloan Digital Sky Survey (SDSS) to gain new insights into current questions in galaxy evolution. The SDSS provides a large, uniform, high quality data set which can be exploited in a number of ways. One avenue pursued here is to use the large sample size to measure precisely the mean properties of galaxies of increasingly narrow parameter ranges. The other route taken is to look for rare objects which open up for exploration new areas in galaxy parameter space. The crux of this thesis is revisiting the classical Kennicutt method for inferring the stellar initial mass function (IMF) from the integrated light properties of galaxies. A large data set (~ 10⁵ galaxies) from the SDSS DR4 is combined with more in-depth modeling and quantitative statistical analysis to search for systematic IMF variations as a function of galaxy luminosity. Galaxy Hα equivalent widths are compared to a broadband color index to constrain the IMF. It is found that for the sample as a whole the best fitting IMF power law slope above 0.5 M_⊙ is Γ = 1.5 ± 0.1 with the error dominated by systematics. Galaxies brighter than around M_r,0.1 = -20 (including galaxies like the Milky Way which has M_r,0.1 ~ -21) are well fit by a universal Γ ~ 1.4 IMF, similar to the classical Salpeter slope, and smooth, exponential star formation histories (SFH). Fainter galaxies prefer steeper IMFs and the quality of the fits reveal that for these galaxies a universal IMF with smooth SFHs is actually a poor assumption. Related projects are also pursued. A targeted photometric search is conducted for strongly lensed Lyman break galaxies (LBG) similar to MS1512-cB58. The evolution of the photometric selection technique is described as are the results of spectroscopic follow-up of the best targets. The serendipitous discovery of two interesting blue compact dwarf galaxies is reported. These

Newton law corrections and instabilities in f(R) gravity with the effective cosmological constant epoch

International Nuclear Information System (INIS)

Nojiri, Shin'ichi; Odintsov, Sergei D.

2007-01-01

We consider class of modified f(R) gravities with the effective cosmological constant epoch at the early and late universe. Such models pass most of solar system tests as well they satisfy to cosmological bounds. Despite their very attractive properties, it is shown that one realistic class of such models may lead to significant Newton law corrections at large cosmological scales. Nevertheless, these corrections are small at solar system as well as at the future universe. Another realistic model with acceptable Newton law regime shows the matter instability

Modeling high-order synchronization epochs and transitions in the cardiovascular system

Science.gov (United States)

García-Álvarez, David; Bahraminasab, Alireza; Stefanovska, Aneta; McClintock, Peter V. E.

2007-12-01

We study a system consisting of two coupled phase oscillators in the presence of noise. This system is used as a model for the cardiorespiratory interaction in wakefulness and anaesthesia. We show that longrange correlated noise produces transitions between epochs with different n:m synchronisation ratios, as observed in the cardiovascular system. Also, we see that, the smaller the noise (specially the one acting on the slower oscillator), the bigger the synchronisation time, exactly as happens in anaesthesia compared with wakefulness. The dependence of the synchronisation time on the couplings, in the presence of noise, is studied; such dependence is softened by low-frequency noise. We show that the coupling from the slow oscillator to the fast one (respiration to heart) plays a more important role in synchronisation. Finally, we see that the isolines with same synchronisation time seem to be a linear combination of the two couplings.

Analysis of Accuracy and Epoch on Back-propagation BFGS Quasi-Newton

Science.gov (United States)

Silaban, Herlan; Zarlis, Muhammad; Sawaluddin

2017-12-01

Back-propagation is one of the learning algorithms on artificial neural networks that have been widely used to solve various problems, such as pattern recognition, prediction and classification. The Back-propagation architecture will affect the outcome of learning processed. BFGS Quasi-Newton is one of the functions that can be used to change the weight of back-propagation. This research tested some back-propagation architectures using classical back-propagation and back-propagation with BFGS. There are 7 architectures that have been tested on glass dataset with various numbers of neurons, 6 architectures with 1 hidden layer and 1 architecture with 2 hidden layers. BP with BFGS improves the convergence of the learning process. The average improvement convergence is 98.34%. BP with BFGS is more optimal on architectures with smaller number of neurons with decreased epoch number is 94.37% with the increase of accuracy about 0.5%.

Amphioxus photoreceptors insights into the evolution of vertebrate opsins, vision and circadian rhythmicity

Czech Academy of Sciences Publication Activity Database

Pergner, Jiří; Kozmik, Zbyněk

2017-01-01

Roč. 61, č. 10-12 (2017), s. 665-681 ISSN 0214-6282 R&D Projects: GA ČR GA17-15374S; GA MŠk(CZ) LM2015062; GA MŠk LO1419 Institutional support: RVO:68378050 Keywords : chordate * opsin evolution * photoreceptor * eye evolution * phototransduction Subject RIV: EB - Genetics ; Molecular Biology OBOR OECD: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology Impact factor: 1.981, year: 2016

Exploring Hydrogen Evolution and the Overpotential

Science.gov (United States)

Lyon, Yana A.; Roberts, Adrienne A.; McMillin, David R.

2015-01-01

The laboratory experiment described provides insight into the energetics of hydrogen evolution at an electrode as well as the intrinsic barrier that typically impedes reaction. In the course of the exercise, students find that Sn(s) is thermodynamically capable of combining with protons to form hydrogen, but that the direct reaction occurs at a…

Parasitism drives host genome evolution: Insights from the Pasteuria ramosa-Daphnia magna system.

Science.gov (United States)

Bourgeois, Yann; Roulin, Anne C; Müller, Kristina; Ebert, Dieter

2017-04-01

Because parasitism is thought to play a major role in shaping host genomes, it has been predicted that genomic regions associated with resistance to parasites should stand out in genome scans, revealing signals of selection above the genomic background. To test whether parasitism is indeed such a major factor in host evolution and to better understand host-parasite interaction at the molecular level, we studied genome-wide polymorphisms in 97 genotypes of the planktonic crustacean Daphnia magna originating from three localities across Europe. Daphnia magna is known to coevolve with the bacterial pathogen Pasteuria ramosa for which host genotypes (clonal lines) are either resistant or susceptible. Using association mapping, we identified two genomic regions involved in resistance to P. ramosa, one of which was already known from a previous QTL analysis. We then performed a naïve genome scan to test for signatures of positive selection and found that the two regions identified with the association mapping further stood out as outliers. Several other regions with evidence for selection were also found, but no link between these regions and phenotypic variation could be established. Our results are consistent with the hypothesis that parasitism is driving host genome evolution. © 2017 The Author(s). Evolution © 2017 The Society for the Study of Evolution.

Thinking social sciences from Latin America at the epochal change

Directory of Open Access Journals (Sweden)

Jaime Antonio Preciado Coronado

2016-07-01

Full Text Available From the legacy of an original disciplinary approach, as the Dependence theory and its Marxian critics, or the neo-structural economic theory founded by The Economic Commission for Latin America (ECLA, the Latin-American social sciences deny the Anglo-European centered approaches, in the way of reaffirming its own critical thinking, including the neo-colonial practices. The challenge for this critical thinking is to be, simultaneously, cosmopolitan and Latin American’s one. In this process, the Latin-American social thinking is regaining its own originality and its vigorous proposals, thanks to a rich south-south dialogue, that implies a global character of its reflections and the questioning of its universal references. Although neither classical nor western Marxism are hegemonic within critical theory, the (neo Marxism enriched with criticism of the coloniality of power, the theory of World-System, critical geopolitics and political ecology recover the field of critical theory in key founder of an epochal thinking time. Epistemological debates with post-structuralism and postmodern approaches configure various recent developments in critical theory

Enhancer Evolution across 20 Mammalian Species

Science.gov (United States)

Villar, Diego; Berthelot, Camille; Aldridge, Sarah; Rayner, Tim F.; Lukk, Margus; Pignatelli, Miguel; Park, Thomas J.; Deaville, Robert; Erichsen, Jonathan T.; Jasinska, Anna J.; Turner, James M.A.; Bertelsen, Mads F.; Murchison, Elizabeth P.; Flicek, Paul; Odom, Duncan T.

2015-01-01

Summary The mammalian radiation has corresponded with rapid changes in noncoding regions of the genome, but we lack a comprehensive understanding of regulatory evolution in mammals. Here, we track the evolution of promoters and enhancers active in liver across 20 mammalian species from six diverse orders by profiling genomic enrichment of H3K27 acetylation and H3K4 trimethylation. We report that rapid evolution of enhancers is a universal feature of mammalian genomes. Most of the recently evolved enhancers arise from ancestral DNA exaptation, rather than lineage-specific expansions of repeat elements. In contrast, almost all liver promoters are partially or fully conserved across these species. Our data further reveal that recently evolved enhancers can be associated with genes under positive selection, demonstrating the power of this approach for annotating regulatory adaptations in genomic sequences. These results provide important insight into the functional genetics underpinning mammalian regulatory evolution. PMID:25635462

Mesozoic-Cenozoic tectonic evolution and its relation to sandstone-type uranium mineralization in northern Tarim area--Evidence from apatite fission track

International Nuclear Information System (INIS)

Liu Hongxu; Dong Wenming; Liu Zhangyue; Chen Xiaolin

2009-01-01

The apatite fission track dating and inversion result of geological thermal history of four rock specimens from Sawafuqi area and Talike area in northern Tarim Basin show that two areas uplifted at different ages. The apatite fission track ages of Sawafuqi range from 3.5 to 3.9 Ma, while the ages of Talike range from 53 to 59 Ma. The thermal history recorded by rock samples reveals that there are at least three prominent cooling phases since Late Cretaceous epoch. Detailed study was made on the division of uplifting stages during Mesozoic and Cenozoic tectonic evolution with the existing data in northern Tarim area. And new ideas on tectonic evolution and sandstone-type uranium mineralization have been put forward by combining with the sandstone-type uranium mineralization ages in this area.(authors)

Superposed epoch analysis of pressure and magnetic field configuration changes in the plasma sheet

International Nuclear Information System (INIS)

Kistler, L.M.; Moebius, E.; Baumjohann, W.; Nagai, T.

1993-01-01

The authors report on an analysis of pressure and magnetic configuration within the plasma sheet following the initiation of substorm events. They have constructed this time dependent picture by using an epoch analysis of data from the AMPTE/IRM spacecraft. This analysis procedure can be used to construct a unified picture of events, provided they are reproducible, from a statistical analysis of a series of point measurements. The authors first determine the time dependent pressure changes in the plasma sheet. With some simplifying assumptions they then determine the z dependence of the pressure profiles, and from this distribution determine how field lines in the plasma sheet map to the neutral sheet

Enhanced dewaterability of sludge during anaerobic digestion with thermal hydrolysis pretreatment: New insights through structure evolution.

Science.gov (United States)

Zhang, Jingsi; Li, Ning; Dai, Xiaohu; Tao, Wenquan; Jenkinson, Ian R; Li, Zhuo

2017-12-19

Comprehensive insights into the sludge digestate dewaterability were gained through porous network structure of sludge. We measured the evolution of digestate dewaterability, represented by the solid content of centrifugally dewatered cake, in high-solids sequencing batch digesters with and without thermal hydrolysis pretreatment (THP). The results show that the dewaterability of the sludge after digestion was improved by 3.5% (±0.5%) for unpretreated sludge and 5.1% (±0.4%) for thermally hydrolyzed sludge. Compared to the unpretreated sludge digestate, thermal hydrolysis pretreatment eventually resulted in an improvement of dewaterability by 4.6% (±0.5%). Smaller particle size and larger surface area of sludge were induced by thermal hydrolysis and anaerobic digestion treatments. The structure strength and compactness of sludge, represented by elastic modulus and fractal dimension respectively, decreased with increase of digestion time. The porous network structure was broken up by thermal hydrolysis pretreatment and was further weakened during anaerobic digestion, which correspondingly improved the dewaterability of digestates. The logarithm of elastic modulus increased linearly with fractal dimension regardless of the pretreatment. Both fractal dimension and elastic modulus showed linear relationship with dewaterability. The rheological characterization combined with the analysis of fractal dimension of sewage sludge porous network structure was found applicable in quantitative evaluation of sludge dewaterability, which depended positively on both thermal hydrolysis and anaerobic digestion. Copyright © 2017 Elsevier Ltd. All rights reserved.

The (R)evolution of China: Offshore Wind Diffusion

DEFF Research Database (Denmark)

Poulsen, Thomas; Hasager, Charlotte Bay

2017-01-01

This research presents an industry level gap analysis for Chinese offshore wind, which serves as a way to illuminate how China may fast track industry evolution. The research findings provide insight into how the Chinese government strongly and systematically decrees state-owned Chinese firms to ...

Spatiotemporal evolution of premonitory fault slip prior to stick-slip instability: New insight into the earthquake preparation

Science.gov (United States)

Zhuo, Y. Q.; Liu, P.; Guo, Y.; Ji, Y.; Ma, J.

2017-12-01

Premonitory fault slip, which begins with quasistatic propagation followed by quasidynamic propagation, may be a key clue bridging the "stick" state and "slip" state of a fault. More attentions have been paid for a long time to the temporal resolution of measurement than the spatial resolution, leading to the incomplete interpretation for the spatial evolution of premonitory slip, particularly during the quasistatic phase. In the present study, measurement of the quasistatic propagation of premonitory slip is achieved at an ultrahigh spatial resolution via a digital image correlation method. Multiple premonitory slip zones are observed and found to be controlled spatially by the fault contact heterogeneity, particularly the strong contact patches that prevent the propagation of premonitory slip and accumulate strain. As a result, premonitory slip is accelerated within constrained week contact spaces and consequently triggers the breakout of quasidynamic propagation. The results provide new insights into the quasistatic propagation of premonitory slip and may offer new interpretations for the earthquake nucleation process. This work is fund by the National Natural Science Foundation of China (Grant No. 41572181), the Basic Scientific Funding of Chinese National Nonprofit Institutes (Grant No. IGCEA1415, IGCEA1525), and the Early-Stage Work of Key Breakthrough Plan in Seismology from China Earthquake Administration.

Will nonlinear peculiar velocity and inhomogeneous reionization spoil 21 cm cosmology from the epoch of reionization?

Science.gov (United States)

Shapiro, Paul R; Mao, Yi; Iliev, Ilian T; Mellema, Garrelt; Datta, Kanan K; Ahn, Kyungjin; Koda, Jun

2013-04-12

The 21 cm background from the epoch of reionization is a promising cosmological probe: line-of-sight velocity fluctuations distort redshift, so brightness fluctuations in Fourier space depend upon angle, which linear theory shows can separate cosmological from astrophysical information. Nonlinear fluctuations in ionization, density, and velocity change this, however. The validity and accuracy of the separation scheme are tested here for the first time, by detailed reionization simulations. The scheme works reasonably well early in reionization (≲40% ionized), but not late (≳80% ionized).

The Ongoing Evolution of the K2-22 System

Science.gov (United States)

Colon, Knicole D.; Zhou, George; Shporer, Avi; Collins, Karen A.; Bieryla, Allyson; Latham, David W.; Espinoza, Nestor; Murgas, Felipe; Pattarakijwanich, Petchara; Awiphan, Supachai; TECH Collaboration

2018-06-01

Of the thousands of exoplanets known, only three disintegrating planets have been identified. These disintegrating planets appear to have tails of dusty material that produce asymmetric transit shapes. K2-22b is one of these few disintegrating planets discovered to date, and its light curve not only displays highly variable transit depths but also uniquely displays evidence of a leading dust tail. Here, we present results from a large ground-based photometric observing campaign of the K2-22 system that took place between December 2016 and May 2017, which we use to investigate the evolution of the transit of K2-22b. Last observed in early 2015, in these new observations we recover the transit around the expected time and measure a typical depth of K2-22b, although the overall shallowness of the transit makes a detailed analysis of the transit shape and timing difficult. In addition, we find no strong evidence of wavelength-dependent transit depths for epochs where we have simultaneous coverage at multiple wavelengths. Given the observed decrease in the transit depth between 2015 and 2017, we encourage continued high-precision photometric monitoring of this system in order to further constrain the evolution timescale and to aid comparative studies with the other few disintegrating planets known.

Dynamical evolution of star-forming regions - II. Basic kinematics

Science.gov (United States)

Parker, Richard J.; Wright, Nicholas J.

2016-04-01

We follow the dynamical evolution of young star-forming regions with a wide range of initial conditions and examine how the radial velocity dispersion, σ, evolves over time. We compare this velocity dispersion to the theoretically expected value for the velocity dispersion if a region were in virial equilibrium, σvir and thus assess the virial state (σ/σvir) of these systems. We find that in regions that are initially subvirial, or in global virial equilibrium but subvirial on local scales, the system relaxes to virial equilibrium within several million years, or roughly 25-50 crossing times, according to the measured virial ratio. However, the measured velocity dispersion, σ, appears to be a bad diagnostic of the current virial state of these systems as it suggests that they become supervirial when compared to the velocity dispersion estimated from the virial mass, σvir. We suggest that this discrepancy is caused by the fact that the regions are never fully relaxed, and that the early non-equilibrium evolution is imprinted in the one-dimensional velocity dispersion at these early epochs. If measured early enough (interquartile range (IQR) dispersion, with measures of spatial structure, places stronger constraints on the dynamical history of a region than using the velocity dispersion in isolation.

FIVE NEW TRANSIT EPOCHS OF THE EXOPLANET OGLE-TR-111b

International Nuclear Information System (INIS)

Hoyer, S.; Rojo, P.; Lopez-Morales, M.; DIaz, R. F.; Chambers, J.; Minniti, D.

2011-01-01

We report five new transit epochs of the extrasolar planet OGLE-TR-111b, observed in the v-HIGH and Bessell I bands with the FORS1 and FORS2 at the ESO Very Large Telescope between 2008 April and May. The new transits have been combined with all previously published transit data for this planet to provide a new transit timing variations (TTVs) analysis of its orbit. We find no TTVs with amplitudes larger than 1.5 minutes over a four-year observation time baseline, in agreement with the recent result by Adams et al. Dynamical simulations fully exclude the presence of additional planets in the system with masses greater than 1.3, 0.4, and 0.5 M + at the 3:2, 1:2, and 2:1 resonances, respectively. We also place an upper limit of about 30 M + on the mass of potential second planets in the region between the 3:2 and 1:2 mean-motion resonances.

Radio Evolution of Supernova Remnants Including Nonlinear Particle Acceleration: Insights from Hydrodynamic Simulations

Science.gov (United States)

Pavlović, Marko Z.; Urošević, Dejan; Arbutina, Bojan; Orlando, Salvatore; Maxted, Nigel; Filipović, Miroslav D.

2018-01-01

We present a model for the radio evolution of supernova remnants (SNRs) obtained by using three-dimensional hydrodynamic simulations coupled with nonlinear kinetic theory of cosmic-ray (CR) acceleration in SNRs. We model the radio evolution of SNRs on a global level by performing simulations for a wide range of the relevant physical parameters, such as the ambient density, supernova (SN) explosion energy, acceleration efficiency, and magnetic field amplification (MFA) efficiency. We attribute the observed spread of radio surface brightnesses for corresponding SNR diameters to the spread of these parameters. In addition to our simulations of Type Ia SNRs, we also considered SNR radio evolution in denser, nonuniform circumstellar environments modified by the progenitor star wind. These simulations start with the mass of the ejecta substantially higher than in the case of a Type Ia SN and presumably lower shock speed. The magnetic field is understandably seen as very important for the radio evolution of SNRs. In terms of MFA, we include both resonant and nonresonant modes in our large-scale simulations by implementing models obtained from first-principles, particle-in-cell simulations and nonlinear magnetohydrodynamical simulations. We test the quality and reliability of our models on a sample consisting of Galactic and extragalactic SNRs. Our simulations give Σ ‑ D slopes between ‑4 and ‑6 for the full Sedov regime. Recent empirical slopes obtained for the Galactic samples are around ‑5, while those for the extragalactic samples are around ‑4.

Incorporating evolutionary insights to improve ecotoxicology for freshwater species

Science.gov (United States)

Brady, Steven P.; Richardson, Jonathan L.; Kunz, Bethany K.

2017-01-01

Ecotoxicological studies have provided extensive insights into the lethal and sublethal effects of environmental contaminants. These insights are critical for environmental regulatory frameworks, which rely on knowledge of toxicity for developing policies to manage contaminants. While varied approaches have been applied to ecotoxicological questions, perspectives related to the evolutionary history of focal species or populations have received little consideration. Here, we evaluate chloride toxicity from the perspectives of both macroevolution and contemporary evolution. First, by mapping chloride toxicity values derived from the literature onto a phylogeny of macroinvertebrates, fish, and amphibians, we tested whether macroevolutionary relationships across species and taxa are predictive of chloride tolerance. Next, we conducted chloride exposure tests for two amphibian species to assess whether potential contemporary evolutionary change associated with environmental chloride contamination influences chloride tolerance across local populations. We show that explicitly evaluating both macroevolution and contemporary evolution can provide important and even qualitatively different insights from those obtained via traditional ecotoxicological studies. While macroevolutionary perspectives can help forecast toxicological end points for species with untested sensitivities, contemporary evolutionary perspectives demonstrate the need to consider the environmental context of exposed populations when measuring toxicity. Accounting for divergence among populations of interest can provide more accurate and relevant information related to the sensitivity of populations that may be evolving in response to selection from contaminant exposure. Our data show that approaches accounting for and specifically examining variation among natural populations should become standard practice in ecotoxicology.

Evolution of galaxies clustering in the VIMOS-VLT Deep Survey

International Nuclear Information System (INIS)

Meneux, Baptiste

2005-01-01

The recent surveys of the Universe highlighted the presence of structures in the matter distribution, such as filaments and voids. To study the evolution of the galaxy spatial distribution, it is necessary to know their accurate position in a three dimensional space. This thesis took place within the framework of the VIMOS-VLT Deep Survey (VVDS). Its goal is to measure some 100000 redshifts to study the formation and evolution of the galaxies and large scale structures of the Universe up to z∼5. After having made a review of our knowledge of the galaxies distribution, then introduced the VVDS, I present the measurement and the evolution of the real-space two-point correlation function from the first epoch data of the VVDS, the largest sample of 10759 spectra ever acquired up to I_A_B = 24. I developed a whole set of programs made available to the VVDS consortium to easily measure the clustering length of galaxies in a given redshift range, with its associated errors, correcting the effects of the VVDS observing strategy. This tool enabled to measure the evolution of the real space correlation function of the global galaxies population up to z=2. I then extended this study dividing the full galaxies sample by spectral type and color. Finally, combining the GALEX data to the VVDS has allowed me to measure the clustering of an ultraviolet-selected sample of galaxies up to z∼1. This is the first time that such measurements are carried out on such a so long range of cosmic time. The results presented in this thesis are thus establishing a new reference in the field. (author) [fr

The evolution of comets and the detectability of Extra-Solar Oort Clouds

International Nuclear Information System (INIS)

Stern, S.A.

1989-01-01

According the standard theory, comets are natural products of solar system formation, ejected to the Oort Cloud by gravitational scattering events during the epoch of giant planet formation. Stored far from the Sun for billions of years, comets almost certainly contain a record of the events which occurred during (and perhaps even before) the epoch of planetary formation. Two themes are examined of the evolutionary processes that affect comets in the Oort Cloud, and a search for evidence of Extra-Solar Oort Clouds (ESOCs). With regard to cometary evolution in the Oort Cloud, it was found that luminous O stars and supernovae have heated the surface layers of all comets on numerous occasions to 20 to 30 K and perhaps once to 50 K. Interstellar medium (ISM) interactions blow small grains out of the Oort Clouds, and erode the upper few hundred g/cu cm of material from cometary surfaces. The findings presented contradict the standard view that comets do not undergo physical change in the Oort Cloud. A logical consequence of the intimate connection between the Oort Cloud and our planetary system is that the detection of comet clouds around other stars would strongly indicate the sites of extant extra-solar planetary systems. A search was conducted for infrared IR emission from debris in ESOCs. After examining 17 stars using the Infrared Astronomical Satellite data base, only upper limits on ESOC emission could be set

Dental Calculus and the Evolution of the Human Oral Microbiome.

Science.gov (United States)

Warinner, Christina

2016-07-01

Characterizing the evolution of the oral microbiome is a challenging, but increasingly feasible, task. Recently, dental calculus has been shown to preserve ancient biomolecules from the oral microbiota, host tissues and diet for tens of thousands of years. As such, it provides a unique window into the ancestral oral microbiome. This article reviews recent advancements in ancient dental calculus research and emerging insights into the evolution and ecology of the human oral microbiome.

Comets and the origin and evolution of life

CERN Document Server

McKay, Christopher P

2006-01-01

Nine years after the publication of Comets and the Origin and Evolution of Life, one of the pioneering books in Astrobiology, this second edition revisits the role comets may have played in the origins and evolution of life. Recent analyses of Antarctic micrometeorites and ancient rocks in Australia and South Africa, the continuing progress in discovering complex organic macromolecules in comets, protostars and interstellar clouds, new insights into organic synthesis in comets, and numerical simulations of comet impacts on the Earth and other members of the solar system yield a spectacular wea

Evolution of circadian rhythms: from bacteria to human.

Science.gov (United States)

Bhadra, Utpal; Thakkar, Nirav; Das, Paromita; Pal Bhadra, Manika

2017-07-01

The human body persists in its rhythm as per its initial time zone, and transition always occur according to solar movements around the earth over 24 h. While traveling across different latitudes and longitudes, at the pace exceeding the earth's movement, the changes in the external cues exceed the level of toleration of the body's biological clock. This poses an alteration in our physiological activities of sleep-wake pattern, mental alertness, organ movement, and eating habits, causing them to temporarily lose the track of time. This is further re-synchronized with the physiological cues of the destination over time. The mechanism of resetting of the clocks with varying time zones and cues occur in organisms from bacteria to humans. It is the result of the evolution of different pathways and molecular mechanisms over the time. There has been evolution of numerous comprehensive mechanisms using various research tools to get a deeper insight into the rapid turnover of molecular mechanisms in various species. This review reports insights into the evolution of the circadian mechanism and its evolutionary shift which is vital and plays a major role in assisting different organisms to adapt in different zones and controls their internal biological clocks with changing external cues. Copyright © 2017 Elsevier B.V. All rights reserved.

The Evolution of the Stellar Hosts of Radio Galaxies

International Nuclear Information System (INIS)

Lacy, Mark; Bunker, Andrew J.; Ridgway, Susan E.

2000-01-01

We present new near-infrared images of z>0.8 radio galaxies from the flux-limited 7C-iii sample of radio sources for which we have recently obtained almost complete spectroscopic redshifts. The 7C objects have radio luminosities ≅20 times fainter than 3C radio galaxies at a given redshift. The absolute magnitudes of the underlying host galaxies and their scale sizes are only weakly dependent on radio luminosity. Radio galaxy hosts at z∼2 are significantly brighter than the hosts of radio-quiet quasars at similar redshifts and the recent model AGN hosts of Kauffmann and Haehnelt. There is no evidence for strong evolution in scale size, which shows a large scatter at all redshifts. The hosts brighten significantly with redshift, consistent with the passive evolution of a stellar population that formed at z(greater-or-similar sign)3. This scenario is consistent with studies of host galaxy morphology and submillimeter continuum emission, both of which show strong evolution at z(greater-or-similar sign)2.5. The lack of a strong ''redshift cutoff'' in the radio luminosity function to z>4 suggests that the formation epoch of the radio galaxy host population lasts (greater-or-similar sign)1 Gyr, from z(greater-or-similar sign)5 to z∼3. We suggest these facts are best explained by models in which the most massive galaxies and their associated AGN form early because of high baryon densities in the centers of their dark matter haloes. (c) 2000 The American Astronomical Society

INTERFEROMETRIC MONITORING OF GAMMA-RAY BRIGHT AGNs. I. THE RESULTS OF SINGLE-EPOCH MULTIFREQUENCY OBSERVATIONS

Energy Technology Data Exchange (ETDEWEB)

Lee, Sang-Sung; Wajima, Kiyoaki; Algaba, Juan-Carlos; Zhao, Guang-Yao; Hodgson, Jeffrey A.; Byun, Do-Young; Kang, Sincheol; Kim, Soon-Wook; Kino, Motoki [Korea Astronomy and Space Science Institute, 776 Daedeok-daero, Yuseong-gu, Daejeon 34055 (Korea, Republic of); Kim, Dae-Won; Park, Jongho; Kim, Jae-Young; Trippe, Sascha [Department of Physics and Astronomy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826 (Korea, Republic of); Miyazaki, Atsushi [Japan Space Forum, 3-2-1, Kandasurugadai, Chiyoda-ku, Tokyo 101-0062 Japan (Japan); Kim, Jeong-Sook, E-mail: sslee@kasi.re.kr [National Astronomical Observatory of Japan, 2211 Osawa, Mitaka, Tokyo 1818588 (Japan)

2016-11-01

We present results of single-epoch very long baseline interferometry (VLBI) observations of gamma-ray bright active galactic nuclei (AGNs) using the Korean VLBI Network (KVN) at the 22, 43, 86, and 129 GHz bands, which are part of a KVN key science program, Interferometric Monitoring of Gamma-Ray Bright AGNs. We selected a total of 34 radio-loud AGNs of which 30 sources are gamma-ray bright AGNs with flux densities of >6 × 10{sup −10} ph cm{sup −2} s{sup −1}. Single-epoch multifrequency VLBI observations of the target sources were conducted during a 24 hr session on 2013 November 19 and 20. All observed sources were detected and imaged at all frequency bands, with or without a frequency phase transfer technique, which enabled the imaging of 12 faint sources at 129 GHz, except for one source. Many of the target sources are resolved on milliarcsecond scales, yielding a core-jet structure, with the VLBI core dominating the synchrotron emission on a milliarcsecond scale. CLEAN flux densities of the target sources are 0.43–28 Jy, 0.32–21 Jy, 0.18–11 Jy, and 0.35–8.0 Jy in the 22, 43, 86, and 129 GHz bands, respectively. Spectra of the target sources become steeper at higher frequency, with spectral index means of −0.40, −0.62, and −1.00 in the 22–43 GHz, 43–86 GHz and 86–129 GHz bands, respectively, implying that the target sources become optically thin at higher frequencies (e.g., 86–129 GHz).

Galaxy evolution. Black hole feedback in the luminous quasar PDS 456.

Science.gov (United States)

Nardini, E; Reeves, J N; Gofford, J; Harrison, F A; Risaliti, G; Braito, V; Costa, M T; Matzeu, G A; Walton, D J; Behar, E; Boggs, S E; Christensen, F E; Craig, W W; Hailey, C J; Matt, G; Miller, J M; O'Brien, P T; Stern, D; Turner, T J; Ward, M J

2015-02-20

The evolution of galaxies is connected to the growth of supermassive black holes in their centers. During the quasar phase, a huge luminosity is released as matter falls onto the black hole, and radiation-driven winds can transfer most of this energy back to the host galaxy. Over five different epochs, we detected the signatures of a nearly spherical stream of highly ionized gas in the broadband x-ray spectra of the luminous quasar PDS 456. This persistent wind is expelled at relativistic speeds from the inner accretion disk, and its wide aperture suggests an effective coupling with the ambient gas. The outflow's kinetic power larger than 10(46) ergs per second is enough to provide the feedback required by models of black hole and host galaxy coevolution. Copyright © 2015, American Association for the Advancement of Science.

Managing Software Process Evolution

DEFF Research Database (Denmark)

This book focuses on the design, development, management, governance and application of evolving software processes that are aligned with changing business objectives, such as expansion to new domains or shifting to global production. In the context of an evolving business world, it examines...... the complete software process lifecycle, from the initial definition of a product to its systematic improvement. In doing so, it addresses difficult problems, such as how to implement processes in highly regulated domains or where to find a suitable notation system for documenting processes, and provides...... essential insights and tips to help readers manage process evolutions. And last but not least, it provides a wealth of examples and cases on how to deal with software evolution in practice. Reflecting these topics, the book is divided into three parts. Part 1 focuses on software business transformation...

Galaxy evolution in dense environments: a concise HI perspective

NARCIS (Netherlands)

Verheijen, Marc A. W.; Diaferio, Antonaldo

2004-01-01

Observing the neutral hydrogen in galaxy clusters provides crucial insights in the physical processes that influence the evolution of gas-rich galaxies as they migrate from the lower-density filaments through the cluster outskirts into to the higher-density central regions. The morphology-density

Stability of cylindrical thin shell wormhole during evolution of universe from inflation to late time acceleration

Energy Technology Data Exchange (ETDEWEB)

Setare, M.R. [Department of Science, Campus of Bijar, University of Kurdistan,Bijar (Iran, Islamic Republic of); Sepehri, A. [Faculty of Physics, Shahid Bahonar University,P.O. Box 76175, Kerman (Iran, Islamic Republic of)

2015-03-16

In this paper, we consider the stability of cylindrical wormholes during evolution of universe from inflation to late time acceleration epochs. We show that there are two types of cylindrical wormholes. The first type is produced at the corresponding point where k black F-strings are transited to BIon configuration. This wormhole transfers energy from extra dimensions into our universe, causes inflation, loses it’s energy and vanishes. The second type of cylindrical wormhole is created by a tachyonic potential and causes a new phase of acceleration. We show that wormhole parameters grow faster than the scale factor in this era, overtake it at ripping time and lead to the destruction of universe at big rip singularity.

The complete chloroplast genome of banana (Musa acuminata, Zingiberales): insight into plastid monocotyledon evolution.

Science.gov (United States)

Martin, Guillaume; Baurens, Franc-Christophe; Cardi, Céline; Aury, Jean-Marc; D'Hont, Angélique

2013-01-01

Banana (genus Musa) is a crop of major economic importance worldwide. It is a monocotyledonous member of the Zingiberales, a sister group of the widely studied Poales. Most cultivated bananas are natural Musa inter-(sub-)specific triploid hybrids. A Musa acuminata reference nuclear genome sequence was recently produced based on sequencing of genomic DNA enriched in nucleus. The Musa acuminata chloroplast genome was assembled with chloroplast reads extracted from whole-genome-shotgun sequence data. The Musa chloroplast genome is a circular molecule of 169,972 bp with a quadripartite structure containing two single copy regions, a Large Single Copy region (LSC, 88,338 bp) and a Small Single Copy region (SSC, 10,768 bp) separated by Inverted Repeat regions (IRs, 35,433 bp). Two forms of the chloroplast genome relative to the orientation of SSC versus LSC were found. The Musa chloroplast genome shows an extreme IR expansion at the IR/SSC boundary relative to the most common structures found in angiosperms. This expansion consists of the integration of three additional complete genes (rps15, ndhH and ycf1) and part of the ndhA gene. No such expansion has been observed in monocots so far. Simple Sequence Repeats were identified in the Musa chloroplast genome and a new set of Musa chloroplastic markers was designed. The complete sequence of M. acuminata ssp malaccensis chloroplast we reported here is the first one for the Zingiberales order. As such it provides new insight in the evolution of the chloroplast of monocotyledons. In particular, it reinforces that IR/SSC expansion has occurred independently several times within monocotyledons. The discovery of new polymorphic markers within Musa chloroplast opens new perspectives to better understand the origin of cultivated triploid bananas.

The complete chloroplast genome of banana (Musa acuminata, Zingiberales: insight into plastid monocotyledon evolution.

Directory of Open Access Journals (Sweden)

Guillaume Martin

Full Text Available Banana (genus Musa is a crop of major economic importance worldwide. It is a monocotyledonous member of the Zingiberales, a sister group of the widely studied Poales. Most cultivated bananas are natural Musa inter-(sub-specific triploid hybrids. A Musa acuminata reference nuclear genome sequence was recently produced based on sequencing of genomic DNA enriched in nucleus.The Musa acuminata chloroplast genome was assembled with chloroplast reads extracted from whole-genome-shotgun sequence data. The Musa chloroplast genome is a circular molecule of 169,972 bp with a quadripartite structure containing two single copy regions, a Large Single Copy region (LSC, 88,338 bp and a Small Single Copy region (SSC, 10,768 bp separated by Inverted Repeat regions (IRs, 35,433 bp. Two forms of the chloroplast genome relative to the orientation of SSC versus LSC were found. The Musa chloroplast genome shows an extreme IR expansion at the IR/SSC boundary relative to the most common structures found in angiosperms. This expansion consists of the integration of three additional complete genes (rps15, ndhH and ycf1 and part of the ndhA gene. No such expansion has been observed in monocots so far. Simple Sequence Repeats were identified in the Musa chloroplast genome and a new set of Musa chloroplastic markers was designed.The complete sequence of M. acuminata ssp malaccensis chloroplast we reported here is the first one for the Zingiberales order. As such it provides new insight in the evolution of the chloroplast of monocotyledons. In particular, it reinforces that IR/SSC expansion has occurred independently several times within monocotyledons. The discovery of new polymorphic markers within Musa chloroplast opens new perspectives to better understand the origin of cultivated triploid bananas.

Spectra of Earth-like Planets through Geological Evolution around FGKM Stars

Science.gov (United States)

Rugheimer, S.; Kaltenegger, L.

2018-02-01

Future observations of terrestrial exoplanet atmospheres will occur for planets at different stages of geological evolution. We expect to observe a wide variety of atmospheres and planets with alternative evolutionary paths, with some planets resembling Earth at different epochs. For an Earth-like atmospheric time trajectory, we simulate planets from the prebiotic to the current atmosphere based on geological data. We use a stellar grid F0V to M8V ({T}{eff}=7000–2400 K) to model four geological epochs of Earth's history corresponding to a prebiotic world (3.9 Ga), the rise of oxygen at 2.0 Ga and at 0.8 Ga, and the modern Earth. We show the VIS–IR spectral features, with a focus on biosignatures through geological time for this grid of Sun-like host stars and the effect of clouds on their spectra. We find that the observability of biosignature gases reduces with increasing cloud cover and increases with planetary age. The observability of the visible O2 feature for lower concentrations will partly depend on clouds, which, while slightly reducing the feature, increase the overall reflectivity, and thus the detectable flux of a planet. The depth of the IR ozone feature contributes substantially to the opacity at lower oxygen concentrations, especially for the high near-UV stellar environments around F stars. Our results are a grid of model spectra for atmospheres representative of Earth's geological history to inform future observations and instrument design and are available online at http://carlsaganinstitute.org/data/.

The Jujube Genome Provides Insights into Genome Evolution and the Domestication of Sweetness/Acidity Taste in Fruit Trees.

Science.gov (United States)

Huang, Jian; Zhang, Chunmei; Zhao, Xing; Fei, Zhangjun; Wan, KangKang; Zhang, Zhong; Pang, Xiaoming; Yin, Xiao; Bai, Yang; Sun, Xiaoqing; Gao, Lizhi; Li, Ruiqiang; Zhang, Jinbo; Li, Xingang

2016-12-01

Jujube (Ziziphus jujuba Mill.) belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic and nutritional value. Here, we report a draft genome of the dry jujube cultivar 'Junzao' and the genome resequencing of 31 geographically diverse accessions of cultivated and wild jujubes (Ziziphus jujuba var. spinosa). Comparative analysis revealed that the genome of 'Dongzao', a fresh jujube, was ~86.5 Mb larger than that of the 'Junzao', partially due to the recent insertions of transposable elements in the 'Dongzao' genome. We constructed eight proto-chromosomes of the common ancestor of Rhamnaceae and Rosaceae, two sister families in the order Rosales, and elucidated the evolutionary processes that have shaped the genome structures of modern jujubes. Population structure analysis revealed the complex genetic background of jujubes resulting from extensive hybridizations between jujube and its wild relatives. Notably, several key genes that control fruit organic acid metabolism and sugar content were identified in the selective sweep regions. We also identified S-locus genes controlling gametophytic self-incompatibility and investigated haplotype patterns of the S locus in the jujube genomes, which would provide a guideline for parent selection for jujube crossbreeding. This study provides valuable genomic resources for jujube improvement, and offers insights into jujube genome evolution and its population structure and domestication.

Age of acquisition predicts rate of lexical evolution.

Science.gov (United States)

Monaghan, Padraic

2014-12-01

The processes taking place during language acquisition are proposed to influence language evolution. However, evidence demonstrating the link between language learning and language evolution is, at best, indirect, constituting studies of laboratory-based artificial language learning studies or computational simulations of diachronic change. In the current study, a direct link between acquisition and evolution is established, showing that for two hundred fundamental vocabulary items, the age at which words are acquired is a predictor of the rate at which they have changed in studies of language evolution. Early-acquired words are more salient and easier to process than late-acquired words, and these early-acquired words are also more stably represented within the community's language. Analysing the properties of these early-acquired words potentially provides insight into the origins of communication, highlighting features of words that have been ultra-conserved in language. Copyright © 2014 Elsevier B.V. All rights reserved.

Contemporary Ecological Interactions Improve Models of Past Trait Evolution.

Science.gov (United States)

Hutchinson, Matthew C; Gaiarsa, Marília P; Stouffer, Daniel B

2018-02-20

Despite the fact that natural selection underlies both traits and interactions, evolutionary models often neglect that ecological interactions may, and in many cases do, influence the evolution of traits. Here, we explore the interdependence of ecological interactions and functional traits in the pollination associations of hawkmoths and flowering plants. Specifically, we develop an adaptation of the Ornstein-Uhlenbeck model of trait evolution that allows us to study the influence of plant corolla depth and observed hawkmoth-plant interactions on the evolution of hawkmoth proboscis length. Across diverse modelling scenarios, we find that the inclusion of contemporary interactions can provide a better description of trait evolution than the null expectation. Moreover, we show that the pollination interactions provide more-likely models of hawkmoth trait evolution when interactions are considered at increasingly finescale groups of hawkmoths. Finally, we demonstrate how the results of best-fit modelling approaches can implicitly support the association between interactions and trait evolution that our method explicitly examines. In showing that contemporary interactions can provide insight into the historical evolution of hawkmoth proboscis length, we demonstrate the clear utility of incorporating additional ecological information to models designed to study past trait evolution.

Origin, development, and evolution of butterfly eyespots.

Science.gov (United States)

Monteiro, Antónia

2015-01-07

This article reviews the latest developments in our understanding of the origin, development, and evolution of nymphalid butterfly eyespots. Recent contributions to this field include insights into the evolutionary and developmental origin of eyespots and their ancestral deployment on the wing, the evolution of eyespot number and eyespot sexual dimorphism, and the identification of genes affecting eyespot development and black pigmentation. I also compare features of old and more recently proposed models of eyespot development and propose a schematic for the genetic regulatory architecture of eyespots. Using this schematic I propose two hypotheses for why we observe limits to morphological diversity across these serially homologous traits.

The Transformation of Cyavana: A Case Study in Narrative Evolution

Directory of Open Access Journals (Sweden)

Emily West

2017-03-01

Full Text Available The assessment of possible genetic relationships between pairs of proposed narrative parallels currently relies on subjective conventional wisdom-based criteria. This essay presents an attempt at categorizing patterns of narrative evolution through the comparison of variants of orally-composed, fixed-text Sanskrit tales. Systematic examination of the changes that took place over the developmental arc of _The Tale of Cyavana_ offers a number of insights that may be applied to the understanding of the evolution of oral narratives in general. An evidence-based exposition of the principles that govern the process of narrative evolution could provide more accurate diagnostic tools for evaluating narrative parallels.

The evolution of CHROMOMETHYLASES and gene body DNA methylation in plants

OpenAIRE

Leebens-Mack, Jim; Griffin, Patrick; Rohr, Nicholas; Niederhuth, Chad; Ji, Lexiang; Bewick, Adam; Schmitz, Robert

2017-01-01

Background The evolution of gene body methylation (gbM), its origins, and its functional consequences are poorly understood. By pairing the largest collection of transcriptomes (>1000) and methylomes (77) across Viridiplantae, we provide novel insights into the evolution of gbM and its relationship to CHROMOMETHYLASE (CMT) proteins. Results CMTs are evolutionary conserved DNA methyltransferases in Viridiplantae. Duplication events gave rise to what are now referred to as CMT1, 2 and 3. Indepe...

The GC-Rich Mitochondrial and Plastid Genomes of the Green Alga Coccomyxa Give Insight into the Evolution of Organelle DNA Nucleotide Landscape

Energy Technology Data Exchange (ETDEWEB)

Smith, David Roy; Burki, Fabien; Yamada, Takashi; Grimwood, Jane; Grigoriev, Igor V.; Van Etten, James L.; Keeling, Patrick J.

2011-05-13

Most of the available mitochondrial and plastid genome sequences are biased towards adenine and thymine (AT) over guanine and cytosine (GC). Examples of GC-rich organelle DNAs are limited to a small but eclectic list of species, including certain green algae. Here, to gain insight in the evolution of organelle nucleotide landscape, we present the GC-rich mitochondrial and plastid DNAs from the trebouxiophyte green alga Coccomyxa sp. C-169. We compare these sequences with other GC-rich organelle DNAs and argue that the forces biasing them towards G and C are nonadaptive and linked to the metabolic and/or life history features of this species. The Coccomyxa organelle genomes are also used for phylogenetic analyses, which highlight the complexities in trying to resolve the interrelationships among the core chlorophyte green algae, but ultimately favour a sister relationship between the Ulvophyceae and Chlorophyceae, with the Trebouxiophyceae branching at the base of the chlorophyte crown.

Slowly switching between environments facilitates reverse evolution in small populations

Science.gov (United States)

Tan, Longzhi; Gore, Jeff

2011-03-01

The rate at which a physical process occurs usually changes the behavior of a system. In thermodynamics, the reversibility of a process generally increases when it occurs at an infinitely slow rate. In biological evolution, adaptations to a new environment may be reversed by evolution in the ancestral environment. Such fluctuating environments are ubiquitous in nature, although how the rate of switching affects reverse evolution is unknown. Here we use a computational approach to quantify evolutionary reversibility as a function of the rate of switching between two environments. For small population sizes, which travel on landscapes as random walkers, we find that both genotypic and phenotypic reverse evolution increase at slow switching rates. However, slow switching of environments decreases evolutionary reversibility for a greedy walker, corresponding to large populations (extensive clonal interference). We conclude that the impact of the switching rate for biological evolution is more complicated than other common physical processes, and that a quantitative approach may yield significant insight into reverse evolution.

The evolution of senescence in the tree of life

DEFF Research Database (Denmark)

Salguero-Gómez, Roberto

The existing theories on the evolution of senescence assume that senescence is inevitable in all organisms. However, recent studies have shown that this is not necessarily true. A better understanding of senescence and its underlying mechanisms could have far-reaching consequences for conservation...... and eco-evolutionary research. This book is the first to offer interdisciplinary perspectives on the evolution of senescence in many species, setting the stage for further developments. It brings together new insights from a wide range of scientific fields and cutting-edge research done on a multitude...

The hydrogen epoch of reionization array dish III: measuring chromaticity of prototype element with reflectometry

Science.gov (United States)

Patra, Nipanjana; Parsons, Aaron R.; DeBoer, David R.; Thyagarajan, Nithyanandan; Ewall-Wice, Aaron; Hsyu, Gilbert; Leung, Tsz Kuk; Day, Cherie K.; de Lera Acedo, Eloy; Aguirre, James E.; Alexander, Paul; Ali, Zaki S.; Beardsley, Adam P.; Bowman, Judd D.; Bradley, Richard F.; Carilli, Chris L.; Cheng, Carina; Dillon, Joshua S.; Fadana, Gcobisa; Fagnoni, Nicolas; Fritz, Randall; Furlanetto, Steve R.; Glendenning, Brian; Greig, Bradley; Grobbelaar, Jasper; Hazelton, Bryna J.; Jacobs, Daniel C.; Julius, Austin; Kariseb, MacCalvin; Kohn, Saul A.; Lebedeva, Anna; Lekalake, Telalo; Liu, Adrian; Loots, Anita; MacMahon, David; Malan, Lourence; Malgas, Cresshim; Maree, Matthys; Martinot, Zachary; Mathison, Nathan; Matsetela, Eunice; Mesinger, Andrei; Morales, Miguel F.; Neben, Abraham R.; Pieterse, Samantha; Pober, Jonathan C.; Razavi-Ghods, Nima; Ringuette, Jon; Robnett, James; Rosie, Kathryn; Sell, Raddwine; Smith, Craig; Syce, Angelo; Tegmark, Max; Williams, Peter K. G.; Zheng, Haoxuan

2018-04-01

Spectral structures due to the instrument response is the current limiting factor for the experiments attempting to detect the redshifted 21 cm signal from the Epoch of Reionization (EoR). Recent advances in the delay spectrum methodology for measuring the redshifted 21 cm EoR power spectrum brought new attention to the impact of an antenna's frequency response on the viability of making this challenging measurement. The delay spectrum methodology provides a somewhat straightforward relationship between the time-domain response of an instrument that can be directly measured and the power spectrum modes accessible to a 21 cm EoR experiment. In this paper, we derive the explicit relationship between antenna reflection coefficient ( S 11) measurements made by a Vector Network Analyzer (VNA) and the extent of additional foreground contaminations in delay space. In the light of this mathematical framework, we examine the chromaticity of a prototype antenna element that will constitute the Hydrogen Epoch of Reionization Array (HERA) between 100 and 200 MHz. These reflectometry measurements exhibit additional structures relative to electromagnetic simulations, but we find that even without any further design improvement, such an antenna element will support measuring spatial k modes with line-of-sight components of k ∥ > 0.2 h Mpc- 1. We also find that when combined with the powerful inverse covariance weighting method used in optimal quadratic estimation of redshifted 21 cm power spectra the HERA prototype elements can successfully measure the power spectrum at spatial modes as low as k ∥ > 0.1 h Mpc- 1. This work represents a major step toward understanding the HERA antenna element and highlights a straightforward method for characterizing instrument response for future experiments designed to detect the 21 cm EoR power spectrum.

The evolution, morphology and development of fern leaves

Directory of Open Access Journals (Sweden)

Alejandra eVasco

2013-09-01

Full Text Available Leaves are lateral determinate structures formed in a predictable sequence (phyllotaxy on the flanks of an indeterminate shoot apical meristem. The origin and evolution of leaves in vascular plants has been widely debated. Being the main conspicuous organ of nearl all vascular plants and often easy to recognize as such, it seems surprising that leaves have had multiple origins. For decades, morphologists, anatomists, paleobotanists, and systematists have contributed data to this debate. More recently, molecular genetic studies have provided insight into leaf evolution and development mainly within angiosperms and, to a lesser extent, lycophytes. There has been recent interest in extending leaf evolutionary developmental studies to other species and lineages, particularly in lycophytes and ferns. Therefore, a review of fern leaf morphology, evolution and development is timely. Here we discuss the theories of leaf evolution in ferns, morphology and diversity of fern leaves, and experimental results of fern leaf development. We summarize what is known about the molecular genetics of fern leaf development and what future studies might tell us about the evolution of fern leaf development.

Philosophy, medicine and healthcare: insights from the Italian experience.

Science.gov (United States)

Adinolfi, Paola

2014-09-01

To contribute to our understanding of the relationship between philosophical ideas and medical and healthcare models. A diachronic analysis is put in place in order to evaluate, from an innovative perspective, the influence over the centuries on medical and healthcare models of two philosophical concepts, particularly relevant for health: how Man perceives his identity and how he relates to Nature. Five epochs are identified--the Archaic Age, Classical Antiquity, the Middle Ages, the Modern Age, the 'Postmodern' Era--which can be seen, à la Foucault, as 'fragments between philosophical fractures'. From a historical background perspective, up to the early 1900s progress in medical and healthcare models has moved on a par with the evolution of philosophical debate. Following the Second World War, the Health Service started a series of reforms, provoked by anti-positivistic philosophical transformations. The three main reforms carried out however failed and the medical establishment remained anchored to a mechanical, reductionist approach, perfectly in line with the bureaucratic stance of the administrators. In this context, future scenarios are delineated and an anthropo-ecological model is proposed to re-align philosophy, medicine and health care.

Fission track analysis and evolution of mesozoic-paleozoic hydrocarbon resource-rocks headed in Northern Jiangsu-South Yellow sea basin

International Nuclear Information System (INIS)

Xu Hong; Cai Qianzhong; Sun Heqing; Guo Zhenxuan; Yan Guijing; Dai Jing; Liu Dongying

2008-01-01

Fission track data of different geologic epoches from Binhai salient, Yancheng sag, Haian sag, Baiju sag, Gaoyou sag, Hongze sag and Jinhu sag of northern Jiangsu basin and seismic data from Laoshan uplift in South Yellow Sea basin and evolution of Paleozoic hydrocarbon resource-rocks headed in the Northern Jiangsu-South Yellow Sea basin were studied. Results indicate that Binhai salient uplifted in 38-15 Ma, forming 'structure uplifting model', Paleozoic hydrocarbon resource-rocks have the appearance of 'different layers but identical mature, different layers but identical temperature' with Laoshan uplift. All sags have the characters of 'long time heating model', and sedimentations in Cenozoic were exploited by 2 km. Mesozoic-Paleozoic hydrocarbon resource- rocks of Laoshan uplift get ahead of 10 km. Structure evolution was compared with Binhai salient. According to the modeling results of secondary hydrocarbon generation, Mesozoic-Paleozoic hydrocarbon resource-rocks of Laoshan uplift have the good reservoir potentiality and probably become an important new window for sea oil and gas exploration. (authors)

Transition in organ function during the evolution of air-breathing; insights from Arapaima gigas, an obligate air-breathing teleost from the Amazon.

Science.gov (United States)

Brauner, C J; Matey, V; Wilson, J M; Bernier, N J; Val, A L

2004-04-01

The transition from aquatic to aerial respiration is associated with dramatic physiological changes in relation to gas exchange, ion regulation, acid-base balance and nitrogenous waste excretion. Arapaima gigas is one of the most obligate extant air-breathing fishes, representing a remarkable model system to investigate (1) how the transition from aquatic to aerial respiration affects gill design and (2) the relocation of physiological processes from the gills to the kidney during the evolution of air-breathing. Arapaima gigas undergoes a transition from water- to air-breathing during development, resulting in striking changes in gill morphology. In small fish (10 g), the gills are qualitatively similar in appearance to another closely related water-breathing fish (Osteoglossum bicirrhosum); however, as fish grow (100-1000 g), the inter-lamellar spaces become filled with cells, including mitochondria-rich (MR) cells, leaving only column-shaped filaments. At this stage, there is a high density of MR cells and strong immunolocalization of Na(+)/K(+)-ATPase along the outer cell layer of the gill filament. Despite the greatly reduced overall gill surface area, which is typical of obligate air-breathing fish, the gills may remain an important site for ionoregulation and acid-base regulation. The kidney is greatly enlarged in A. gigas relative to that in O. bicirrhosum and may comprise a significant pathway for nitrogenous waste excretion. Quantification of the physiological role of the gill and the kidney in A. gigas during development and in adults will yield important insights into developmental physiology and the evolution of air-breathing.

The origin and evolution of the sexes: Novel insights from a distant eukaryotic linage.

Science.gov (United States)

Mignerot, Laure; Coelho, Susana M

2016-01-01

Sexual reproduction is an extraordinarily widespread phenomenon that assures the production of new genetic combinations in nearly all eukaryotic lineages. Although the core features of sexual reproduction (meiosis and syngamy) are highly conserved, the control mechanisms that determine whether an individual is male or female are remarkably labile across eukaryotes. In genetically controlled sexual systems, gender is determined by sex chromosomes, which have emerged independently and repeatedly during evolution. Sex chromosomes have been studied in only a handful of classical model organism, and empirical knowledge on the origin and evolution of the sexes is still surprisingly incomplete. With the advent of new generation sequencing, the taxonomic breadth of model systems has been rapidly expanding, bringing new ideas and fresh views on this fundamental aspect of biology. This mini-review provides a quick state of the art of how the remarkable richness of the sexual characteristics of the brown algae is helping to increase our knowledge about the evolution of sex determination. Copyright © 2016 Académie des sciences. Published by Elsevier SAS. All rights reserved.

Insights into archaeal evolution and symbiosis from the genomes of a Nanoarchaeon and its crenarchaeal host from Yellowstone National Park

Energy Technology Data Exchange (ETDEWEB)

Podar, Mircea [ORNL; Graham, David E [ORNL; Reysenbach, Anna-Louise [Portland State University; Koonin, Eugene [National Center for Biotechnology Information; Wolf, Yuri [National Center for Biotechnology Information; Makarova, Kira S. [National Center for Biotechnology Information

2013-01-01

A hyperthemophilic member of the Nanoarchaeota from Obsidian Pool, a thermal feature in Yellowstone National Park was characterized using single cell isolation and sequencing, together with its putative host, a Sulfolobales archaeon. This first representative of a non-marine Nanoarchaeota (Nst1) resembles Nanoarchaeum equitans by lacking most biosynthetic capabilities, the two forming a deep-branching archaeal lineage. However, the Nst1 genome is over 20% larger, encodes a complete gluconeogenesis pathway and a full complement of archaeal flagellum proteins. Comparison of the two genomes suggests that the marine and terrestrial Nanoarchaeota lineages share a common ancestor that was already a symbiont of another archaeon. With a larger genome, a smaller repertoire of split protein encoding genes and no split non-contiguous tRNAs, Nst1 appears to have experienced less severe genome reduction than N. equitans. The inferred host of Nst1 is potentially autotrophic, with a streamlined genome and simplified central and energetic metabolism as compared to other Sulfolobales. The two distinct Nanoarchaeota-host genomic data sets offer insights into the evolution of archaeal symbiosis and parasitism and will further enable studies of the cellular and molecular mechanisms of these relationships.

Evolution of passive continental margins and initiation of subduction zones

NARCIS (Netherlands)

Cloetingh, Sierd

1982-01-01

The initiation of subduction is a key element in plate tectonic schemes for the evolution of the Earth's lithosphere. Nevertheless, up to present, the underlying mechanism has not been very well understood (e.g. Dickinson and Seely, 1979; Hager, 1980; Kanamori, 1980). The insight into the initiation

Evolution of passive continental margins and initiation of subduction zones

NARCIS (Netherlands)

Cloetingh, S.A.P.L.

1982-01-01

The initiation of subduction is a key element in plate tectonic schemes for the evolution of the Earth's lithosphere. Nevertheless, up to present, the underlying mechanism has not been very well understood (e.g. Dickinson and Seely, 1979; Hager, 1980; Kanamori, 1980). The insight into the

Effective evolution equations from many-body quantum mechanics

International Nuclear Information System (INIS)

Benedikter, Niels Patriz

2014-01-01

Systems of interest in physics often consist of a very large number of interacting particles. In certain physical regimes, effective non-linear evolution equations are commonly used as an approximation for making predictions about the time-evolution of such systems. Important examples are Bose-Einstein condensates of dilute Bose gases and degenerate Fermi gases. While the effective equations are well-known in physics, a rigorous justification is very difficult. However, a rigorous derivation is essential to precisely understand the range and the limits of validity and the quality of the approximation. In this thesis, we prove that the time evolution of Bose-Einstein condensates in the Gross-Pitaevskii regime can be approximated by the time-dependent Gross-Pitaevskii equation, a cubic non-linear Schroedinger equation. We then turn to fermionic systems and prove that the evolution of a degenerate Fermi gas can be approximated by the time-dependent Hartree-Fock equation (TDHF) under certain assumptions on the semiclassical structure of the initial data. Finally, we extend the latter result to fermions with relativistic kinetic energy. All our results provide explicit bounds on the error as the number of particles becomes large. A crucial methodical insight on bosonic systems is that correlations can be modeled by Bogolyubov transformations. We construct initial data appropriate for the Gross-Pitaevskii regime using a Bogolyubov transformation acting on a coherent state, which amounts to studying squeezed coherent states. As a crucial insight for fermionic systems, we point out a semiclassical structure in states close to the ground state of fermions in a trap. As a convenient language for studying the dynamics of fermionic systems, we use particle-hole transformations.

Insights into metazoan evolution from alvinella pompejana cDNAs

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Thierry Jean-Claude

2010-11-01

Full Text Available Abstract Background Alvinella pompejana is a representative of Annelids, a key phylum for evo-devo studies that is still poorly studied at the sequence level. A. pompejana inhabits deep-sea hydrothermal vents and is currently known as one of the most thermotolerant Eukaryotes in marine environments, withstanding the largest known chemical and thermal ranges (from 5 to 105°C. This tube-dwelling worm forms dense colonies on the surface of hydrothermal chimneys and can withstand long periods of hypo/anoxia and long phases of exposure to hydrogen sulphides. A. pompejana specifically inhabits chimney walls of hydrothermal vents on the East Pacific Rise. To survive, Alvinella has developed numerous adaptations at the physiological and molecular levels, such as an increase in the thermostability of proteins and protein complexes. It represents an outstanding model organism for studying adaptation to harsh physicochemical conditions and for isolating stable macromolecules resistant to high temperatures. Results We have constructed four full length enriched cDNA libraries to investigate the biology and evolution of this intriguing animal. Analysis of more than 75,000 high quality reads led to the identification of 15,858 transcripts and 9,221 putative protein sequences. Our annotation reveals a good coverage of most animal pathways and networks with a prevalence of transcripts involved in oxidative stress resistance, detoxification, anti-bacterial defence, and heat shock protection. Alvinella proteins seem to show a slow evolutionary rate and a higher similarity with proteins from Vertebrates compared to proteins from Arthropods or Nematodes. Their composition shows enrichment in positively charged amino acids that might contribute to their thermostability. The gene content of Alvinella reveals that an important pool of genes previously considered to be specific to Deuterostomes were in fact already present in the last common ancestor of the Bilaterian

The Jujube Genome Provides Insights into Genome Evolution and the Domestication of Sweetness/Acidity Taste in Fruit Trees.

Directory of Open Access Journals (Sweden)

Jian Huang

2016-12-01

Full Text Available Jujube (Ziziphus jujuba Mill. belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic and nutritional value. Here, we report a draft genome of the dry jujube cultivar 'Junzao' and the genome resequencing of 31 geographically diverse accessions of cultivated and wild jujubes (Ziziphus jujuba var. spinosa. Comparative analysis revealed that the genome of 'Dongzao', a fresh jujube, was ~86.5 Mb larger than that of the 'Junzao', partially due to the recent insertions of transposable elements in the 'Dongzao' genome. We constructed eight proto-chromosomes of the common ancestor of Rhamnaceae and Rosaceae, two sister families in the order Rosales, and elucidated the evolutionary processes that have shaped the genome structures of modern jujubes. Population structure analysis revealed the complex genetic background of jujubes resulting from extensive hybridizations between jujube and its wild relatives. Notably, several key genes that control fruit organic acid metabolism and sugar content were identified in the selective sweep regions. We also identified S-locus genes controlling gametophytic self-incompatibility and investigated haplotype patterns of the S locus in the jujube genomes, which would provide a guideline for parent selection for jujube crossbreeding. This study provides valuable genomic resources for jujube improvement, and offers insights into jujube genome evolution and its population structure and domestication.

Evolution and structure of Tomato spotted wilt virus populations: evidence of extensive reassortment and insights into emergence processes.

Science.gov (United States)

Tentchev, Diana; Verdin, Eric; Marchal, Cécile; Jacquet, Monique; Aguilar, Juan M; Moury, Benoît

2011-04-01

Tomato spotted wilt virus (TSWV; genus Tospovirus, family Bunyaviridae) genetic diversity was evaluated by sequencing parts of the three RNA genome segments of 224 isolates, mostly from pepper and tomato crops in southern Europe. Eighty-three per cent of the isolates showed consistent clustering into three clades, corresponding to their geographical origin, Spain, France or the USA, for the three RNA segments. In contrast, the remaining 17% of isolates did not belong to the same clade for the three RNA segments and were shown to be reassortants. Among them, eight different reassortment patterns were observed. Further phylogenetic analyses provided insights into the dynamic processes of the worldwide resurgence of TSWV that, since the 1980s, has followed the worldwide dispersal of the western flower thrips (Frankliniella occidentalis) tospovirus vector. For two clades composed essentially of Old World (OW) isolates, tree topology suggested a local re-emergence of indigenous TSWV populations following F. occidentalis introductions, while it could not be excluded that the ancestors of two other OW clades were introduced from North America contemporarily with F. occidentalis. Finally, estimation of the selection intensity that has affected the evolution of the NSs and nucleocapsid proteins encoded by RNA S of TSWV suggests that the former could be involved in the breakdown of resistance conferred by the Tsw gene in pepper.

The (R)evolution of China: Offshore Wind Diffusion

DEFF Research Database (Denmark)

Poulsen, Thomas; Hasager, Charlotte Bay

2017-01-01

This research presents an industry level gap analysis for Chinese offshore wind, which serves as a way to illuminate how China may fast track industry evolution. The research findings provide insight into how the Chinese government strongly and systematically decrees state-owned Chinese firms...... successfully forge long-term alliances also for future Chinese wind energy export projects. Examples of past efforts of collaboration not yielding desired results have been included as well. At policy level, recommendations are provided on how the evolution of the Chinese offshore wind power industry can...... be fast-tracked to mirror the revolutionary pace, volume, and velocity which the Chinese onshore wind power industry has mustered....

Evolution and development: some insights from evolutionary theory

Directory of Open Access Journals (Sweden)

DAVID JEAN R.

2001-01-01

Full Text Available Developmental biology and evolutionary biology are both mature integrative disciplines which started in the 19th century and then followed parallel and independent scientific pathways. Recently, a genetical component has stepped into both disciplines (developmental genetics and evolutionary genetics pointing out the need for future convergent maturation. Indeed, the Evo-Devo approach is becoming popular among developmental biologists, based on the facts that distant groups share a common ancestry, that precise phylogenies can be worked out and that homologous genes often play similar roles during the development of very different organisms. In this essay, I try to show that the real future of Evo-Devo thinking is still broader. The evolutionary theory is a set of diverse concepts which can and should be used in any biological field. Evolutionary thinking trains to ask « why » questions and to provide logical and plausible answers. It can shed some light on a diversity of general problems such as how to distinguish homologies from analogies, the costs and benefits of multicellularity, the origin of novel structures (e.g. the head, or the evolution of sexual reproduction. In the next decade, we may expect a progressive convergence between developmental genetics and quantitative genetics.

A fossil brain from the Cretaceous of European Russia and avian sensory evolution.

Science.gov (United States)

Kurochkin, Evgeny N; Dyke, Gareth J; Saveliev, Sergei V; Pervushov, Evgeny M; Popov, Evgeny V

2007-06-22

Fossils preserving traces of soft anatomy are rare in the fossil record; even rarer is evidence bearing on the size and shape of sense organs that provide us with insights into mode of life. Here, we describe unique fossil preservation of an avian brain from the Volgograd region of European Russia. The brain of this Melovatka bird is similar in shape and morphology to those of known fossil ornithurines (the lineage that includes living birds), such as the marine diving birds Hesperornis and Enaliornis, but documents a new stage in avian sensory evolution: acute nocturnal vision coupled with well-developed hearing and smell, developed by the Late Cretaceous (ca 90Myr ago). This fossil also provides insights into previous 'bird-like' brain reconstructions for the most basal avian Archaeopteryx--reduction of olfactory lobes (sense of smell) and enlargement of the hindbrain (cerebellum) occurred subsequent to Archaeopteryx in avian evolution, closer to the ornithurine lineage that comprises living birds. The Melovatka bird also suggests that brain enlargement in early avians was not correlated with the evolution of powered flight.

An Extended ADOP for Performance Evaluation of Single-Frequency Single-Epoch Positioning by BDS/GPS in Asia-Pacific Region

Directory of Open Access Journals (Sweden)

Xin Liu

2017-09-01

Full Text Available Single-Frequency Single-Epoch (SFSE high-precision positioning has always been the hot spot of Global Navigation Satellite System (GNSS, and ambiguity dilution of precision (ADOP is a well-known scalar measure for success rate of ambiguity resolution. Traditional ADOP expression is complicated, thus the SFSE extended ADOP (E-ADOP, with the newly defined Summation-Multiplication Ratio of Weight (SMRW and two theorems for short baseline, was developed. This simplifies the ADOP expression; gives a clearer insight into the influences of SMRW and number of satellites on E-ADOP; and makes theoretical analysis of E-ADOP more convenient than that of ADOP, and through that the E-ADOP value can be predicted more accurately than through the ADOP expression for ADOP value. E-ADOP reveals that number of satellites and SMRW or high-elevation satellite are important for ADOP and, through E-ADOP, we studied which factor is dominant to control ADOP in different conditions and make ADOP different between BeiDou Navigation Satellite System (BDS, Global Positioning System (GPS, and BDS/GPS. Based on experimental results of SFSE positioning with different baselines, some conclusions are made: (1 ADOP decreases when new satellites are added mainly because the number of satellites becomes larger; (2 when the number of satellites is constant, ADOP is mainly affected by SMRW; (3 in contrast to systems where the satellites with low-elevation are the majority or where low- and high-elevation satellites are equally distributed, in systems where the high-elevation satellites are the majority, the SMRW mainly makes ADOP smaller, even if there are fewer satellites than in the two previous cases, and the difference in numbers of satellites can be expanded as the proportion of high-elevation satellites becomes larger; and (4 ADOP of BDS is smaller than ADOP of GPS mainly because of its SMRW.

Genomic insights into the Saccharomyces sensu stricto complex.

Science.gov (United States)

Borneman, Anthony R; Pretorius, Isak S

2015-02-01

The Saccharomyces sensu stricto group encompasses species ranging from the industrially ubiquitous yeast Saccharomyces cerevisiae to those that are confined to geographically limited environmental niches. The wealth of genomic data that are now available for the Saccharomyces genus is providing unprecedented insights into the genomic processes that can drive speciation and evolution, both in the natural environment and in response to human-driven selective forces during the historical "domestication" of these yeasts for baking, brewing, and winemaking. Copyright © 2015 by the Genetics Society of America.

Strategy intervention for the evolution of fairness.

Directory of Open Access Journals (Sweden)

Yanling Zhang

Full Text Available The 'irrational' preference for fairness has attracted increasing attention. Although previous studies have focused on the effects of spitefulness on the evolution of fairness, they did not consider non-monotonic rejections shown in behavioral experiments. In this paper, we introduce a non-monotonic rejection in an evolutionary model of the Ultimatum Game. We propose strategy intervention to study the evolution of fairness in general structured populations. By sequentially adding five strategies into the competition between a fair strategy and a selfish strategy, we arrive at the following conclusions. First, the evolution of fairness is inhibited by altruism, but it is promoted by spitefulness. Second, the non-monotonic rejection helps fairness overcome selfishness. Particularly for group-structured populations, we analytically investigate how fairness, selfishness, altruism, and spitefulness are affected by population size, mutation, and migration in the competition among seven strategies. Our results may provide important insights into understanding the evolutionary origin of fairness.

Direct detection of projectile relics from the end of the lunar basin-forming epoch.

Science.gov (United States)

Joy, Katherine H; Zolensky, Michael E; Nagashima, Kazuhide; Huss, Gary R; Ross, D Kent; McKay, David S; Kring, David A

2012-06-15

The lunar surface, a key proxy for the early Earth, contains relics of asteroids and comets that have pummeled terrestrial planetary surfaces. Surviving fragments of projectiles in the lunar regolith provide a direct measure of the types and thus the sources of exogenous material delivered to the Earth-Moon system. In ancient [>3.4 billion years ago (Ga)] regolith breccias from the Apollo 16 landing site, we located mineral and lithologic relics of magnesian chondrules from chondritic impactors. These ancient impactor fragments are not nearly as diverse as those found in younger (3.4 Ga to today) regolith breccias and soils from the Moon or that presently fall as meteorites to Earth. This suggests that primitive chondritic asteroids, originating from a similar source region, were common Earth-Moon-crossing impactors during the latter stages of the basin-forming epoch.

The Early Prevention of Obesity in CHildren (EPOCH Collaboration - an Individual Patient Data Prospective Meta-Analysis

Directory of Open Access Journals (Sweden)

Simes John

2010-11-01

Full Text Available Abstract Background Efforts to prevent the development of overweight and obesity have increasingly focused early in the life course as we recognise that both metabolic and behavioural patterns are often established within the first few years of life. Randomised controlled trials (RCTs of interventions are even more powerful when, with forethought, they are synthesised into an individual patient data (IPD prospective meta-analysis (PMA. An IPD PMA is a unique research design where several trials are identified for inclusion in an analysis before any of the individual trial results become known and the data are provided for each randomised patient. This methodology minimises the publication and selection bias often associated with a retrospective meta-analysis by allowing hypotheses, analysis methods and selection criteria to be specified a priori. Methods/Design The Early Prevention of Obesity in CHildren (EPOCH Collaboration was formed in 2009. The main objective of the EPOCH Collaboration is to determine if early intervention for childhood obesity impacts on body mass index (BMI z scores at age 18-24 months. Additional research questions will focus on whether early intervention has an impact on children's dietary quality, TV viewing time, duration of breastfeeding and parenting styles. This protocol includes the hypotheses, inclusion criteria and outcome measures to be used in the IPD PMA. The sample size of the combined dataset at final outcome assessment (approximately 1800 infants will allow greater precision when exploring differences in the effect of early intervention with respect to pre-specified participant- and intervention-level characteristics. Discussion Finalisation of the data collection procedures and analysis plans will be complete by the end of 2010. Data collection and analysis will occur during 2011-2012 and results should be available by 2013. Trial registration number ACTRN12610000789066

Superposed epoch study of ICME sub-structures near Earth and their effects on Galactic cosmic rays

Science.gov (United States)

Masías-Meza, J. J.; Dasso, S.; Démoulin, P.; Rodriguez, L.; Janvier, M.

2016-08-01

Context. Interplanetary coronal mass ejections (ICMEs) are the interplanetary manifestations of solar eruptions. The overtaken solar wind forms a sheath of compressed plasma at the front of ICMEs. Magnetic clouds (MCs) are a subset of ICMEs with specific properties (e.g. the presence of a flux rope). When ICMEs pass near Earth, ground observations indicate that the flux of Galactic cosmic rays (GCRs) decreases. Aims: The main aims of this paper are to find common plasma and magnetic properties of different ICME sub-structures and which ICME properties affect the flux of GCRs near Earth. Methods: We used a superposed epoch method applied to a large set of ICMEs observed in situ by the spacecraft ACE, between 1998 and 2006. We also applied a superposed epoch analysis on GCRs time series observed with the McMurdo neutron monitors. Results: We find that slow MCs at 1 AU have on average more massive sheaths. We conclude that this is because they are more effectively slowed down by drag during their travel from the Sun. Slow MCs also have a more symmetric magnetic field and sheaths expanding similarly as their following MC, while in contrast, fast MCs have an asymmetric magnetic profile and a sheath in compression. In all types of MCs, we find that the proton density and the temperature and the magnetic fluctuations can diffuse within the front of the MC due to 3D reconnection. Finally, we derive a quantitative model that describes the decrease in cosmic rays as a function of the amount of magnetic fluctuations and field strength. Conclusions: The obtained typical profiles of sheath, MC and GCR properties corresponding to slow, middle, and fast ICMEs, can be used for forecasting or modelling these events, and to better understand the transport of energetic particles in ICMEs. They are also useful for improving future operative space weather activities.

Spatiotemporal evolution of Reaumuria (Tamaricaceae) in Central Asia: insights from molecular biogeography

Science.gov (United States)

Mingli Zhang; Xiaoli Hao; Stewart C. Sanderson; Byalt V. Vyacheslav; Alexander P. Sukhorukov; Xia Zhang

2014-01-01

Reaumuria is an arid adapted genus with a distribution center in Central Asia; its evolution and dispersal is investigated in this paper. Eighteen species of Reaumuria and nine species of two other genera in the Tamaricaceae, Tamarix and Myricaria, were sampled, and four markers ITS, rps16, psbB-psbH, and trnL-trnF were sequenced. The reconstructed phylogenetic tree is...

Study of redshifted H I from the epoch of reionization with drift scan

Energy Technology Data Exchange (ETDEWEB)

Paul, Sourabh; Sethi, Shiv K.; Subrahmanyan, Ravi; Shankar, N. Udaya; Dwarakanath, K. S.; Deshpande, Avinash A. [Raman Research Institute, Bangalore (India); Bernardi, Gianni [Square Kilometre Array South Africa (SKA SA), 3rd Floor, The Park, Park Road, Pinelands 7405 (South Africa); Bowman, Judd D. [Arizona State University, Tempe, AZ85281 (United States); Briggs, Frank; Gaensler, Bryan M. [ARC Centre of Excellence for All-sky Astrophysics (CAASTRO), 44 Rosehill Street, Redfern, NSW 2016 (Australia); Cappallo, Roger J.; Corey, Brian E.; Goeke, Robert F. [MIT Haystack Observatory, Westford, MA 01886 (United States); Emrich, David [Curtin University, Perth (Australia); Greenhill, Lincoln J.; Kasper, Justin C. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Hazelton, Bryna J. [University of Washington, Seattle, WA 98195 (United States); Hewitt, Jacqueline N. [MIT Kavli Institute for Astrophysics and Space Research, 77 Massachusetts Avenue, 37-241, Cambridge, MA 02139 (United States); Johnston-Hollitt, Melanie [Victoria University of Wellington, P.O. Box 600, Wellington 6140 (New Zealand); Kaplan, David L., E-mail: sourabh@rri.res.in, E-mail: sethi@rri.res.in [University of Wisconsin-Milwaukee, Milwaukee, WI 53201 (United States); and others

2014-09-20

Detection of the epoch of reionization (EoR) in the redshifted 21 cm line is a challenging task. Here, we formulate the detection of the EoR signal using the drift scan strategy. This method potentially has better instrumental stability compared to the case where a single patch of sky is tracked. We demonstrate that the correlation time between measured visibilities could extend up to 1-2 hr for an interferometer array such as the Murchison Widefield Array, which has a wide primary beam. We estimate the EoR power based on a cross-correlation of visibilities over time and show that the drift scan strategy is capable of detecting the EoR signal with a signal to noise that is comparable/better compared to the tracking case. We also estimate the visibility correlation for a set of bright point sources and argue that the statistical inhomogeneity of bright point sources might allow their separation from the EoR signal.

GNSS Single Frequency, Single Epoch Reliable Attitude Determination Method with Baseline Vector Constraint

Directory of Open Access Journals (Sweden)

Ang Gong

2015-12-01

Full Text Available For Global Navigation Satellite System (GNSS single frequency, single epoch attitude determination, this paper proposes a new reliable method with baseline vector constraint. First, prior knowledge of baseline length, heading, and pitch obtained from other navigation equipment or sensors are used to reconstruct objective function rigorously. Then, searching strategy is improved. It substitutes gradually Enlarged ellipsoidal search space for non-ellipsoidal search space to ensure correct ambiguity candidates are within it and make the searching process directly be carried out by least squares ambiguity decorrelation algorithm (LAMBDA method. For all vector candidates, some ones are further eliminated by derived approximate inequality, which accelerates the searching process. Experimental results show that compared to traditional method with only baseline length constraint, this new method can utilize a priori baseline three-dimensional knowledge to fix ambiguity reliably and achieve a high success rate. Experimental tests also verify it is not very sensitive to baseline vector error and can perform robustly when angular error is not great.

On the Evolution of the Central Density of Quiescent Galaxies

International Nuclear Information System (INIS)

Tacchella, Sandro; Carollo, C. Marcella; Woo, Joanna; Faber, S. M.; Koo, David C.; Cibinel, Anna; Dekel, Avishai; Renzini, Alvio

2017-01-01

We investigate the origin of the evolution of the population-averaged central stellar mass density (Σ_1) of quiescent galaxies (QGs) by probing the relation between stellar age and Σ_1 at z ∼ 0. We use the Zurich ENvironmental Study (ZENS), which is a survey of galaxy groups with a large fraction of satellite galaxies. QGs shape a narrow locus in the Σ_1– M _⋆ plane, which we refer to as Σ_1 ridgeline. Colors of ( B − I ) and ( I − J ) are used to divide QGs into three age categories: young ( 4 Gyr). At fixed stellar mass, old QGs on the Σ_1 ridgeline have higher Σ_1 than young QGs. This shows that galaxies landing on the Σ_1 ridgeline at later epochs arrive with lower Σ_1, which drives the zeropoint of the ridgeline down with time. We compare the present-day zeropoint of the oldest population at z = 0 with the zeropoint of the quiescent population 4 Gyr back in time, at z = 0.37. These zeropoints are identical, showing that the intrinsic evolution of individual galaxies after they arrive on the Σ_1 ridgeline must be negligible, or must evolve parallel to the ridgeline during this interval. The observed evolution of the global zeropoint of 0.07 dex over the last 4 Gyr is thus largely due to the continuous addition of newly quenched galaxies with lower Σ_1 at later times (“progenitor bias”). While these results refer to the satellite-rich ZENS sample as a whole, our work suggests a similar age–Σ_1 trend for central galaxies.

Two-epoch cross-sectional case record review protocol comparing quality of care of hospital emergency admissions at weekends versus weekdays.

Science.gov (United States)

Bion, Julian; Aldridge, Cassie P; Girling, Alan; Rudge, Gavin; Beet, Chris; Evans, Tim; Temple, R Mark; Roseveare, Chris; Clancy, Mike; Boyal, Amunpreet; Tarrant, Carolyn; Sutton, Elizabeth; Sun, Jianxia; Rees, Peter; Mannion, Russell; Chen, Yen-Fu; Watson, Samuel Ian; Lilford, Richard

2017-12-22

The mortality associated with weekend admission to hospital (the 'weekend effect') has for many years been attributed to deficiencies in quality of hospital care, often assumed to be due to suboptimal senior medical staffing at weekends. This protocol describes a case note review to determine whether there are differences in care quality for emergency admissions (EAs) to hospital at weekends compared with weekdays, and whether the difference has reduced over time as health policies have changed to promote 7-day services. Cross-sectional two-epoch case record review of 20 acute hospital Trusts in England. Anonymised case records of 4000 EAs to hospital, 2000 at weekends and 2000 on weekdays, covering two epochs (financial years 2012-2013 and 2016-2017). Admissions will be randomly selected across the whole of each epoch from Trust electronic patient records. Following training, structured implicit case reviews will be conducted by consultants or senior registrars (senior residents) in acute medical specialities (60 case records per reviewer), and limited to the first 7 days following hospital admission. The co-primary outcomes are the weekend:weekday admission ratio of errors per case record, and a global assessment of care quality on a Likert scale. Error rates will be analysed using mixed effects logistic regression models, and care quality using ordinal regression methods. Secondary outcomes include error typology, error-related adverse events and any correlation between error rates and staffing. The data will also be used to inform a parallel health economics analysis. The project has received ethics approval from the South West Wales Research Ethics Committee (REC): reference 13/WA/0372. Informed consent is not required for accessing anonymised patient case records from which patient identifiers had been removed. The findings will be disseminated through peer-reviewed publications in high-quality journals and through local High-intensity Specialist-Led Acute

The Value of Change: Surprises and Insights in Stellar Evolution

Science.gov (United States)

Bildsten, Lars

2018-01-01

Astronomers with large-format cameras regularly scan the sky many times per night to detect what's changing, and telescopes in space such as Kepler and, soon, TESS obtain very accurate brightness measurements of nearly a million stars over time periods of years. These capabilities, in conjunction with theoretical and computational efforts, have yielded surprises and remarkable new insights into the internal properties of stars and how they end their lives. I will show how asteroseismology reveals the properties of the deep interiors of red giants, and highlight how astrophysical transients may be revealing unusual thermonuclear outcomes from exploding white dwarfs and the births of highly magnetic neutron stars. All the while, stellar science has been accelerated by the availability of open source tools, such as Modules for Experiments in Stellar Astrophysics (MESA), and the nearly immediate availability of observational results.

ON THE SIZE AND COMOVING MASS DENSITY EVOLUTION OF EARLY-TYPE GALAXIES

International Nuclear Information System (INIS)

Van der Wel, Arjen; Bell, Eric F.; Van den Bosch, Frank C.; Gallazzi, Anna; Rix, Hans-Walter

2009-01-01

We present a simple, empirically motivated model that simultaneously predicts the evolution of the mean size and the comoving mass density of massive (>10 11 M sun ) early-type galaxies from z = 2 to the present. First, we demonstrate that some size evolution of the population can be expected simply due to the continuous emergence of early-type galaxies. The Sloan Digital Sky Survey (SDSS) data reveal that in the present-day universe more compact early-type galaxies with a given dynamical mass have older stellar populations. This implies that with increasing look-back time, the more extended galaxies will be more and more absent from the population. In contrast, at a given stellar velocity dispersion, SDSS data show that there is no relation between size and age, which implies that the velocity dispersion can be used to estimate the epoch at which galaxies stopped forming stars, turning into early-type galaxies. Based on this, we define an empirically motivated, redshift-dependent velocity dispersion threshold above which galaxies do not form stars at a significant rate, which we associate with the transformation into early-type galaxies. Applying this 'formation' criterion to a large sample of nearby early-type galaxies, we predict the redshift evolution in the size distribution and the comoving mass density. The resulting evolution in the mean size is roughly half of the observed evolution. Then we include a prescription for the merger histories of galaxies between the 'formation' redshift and the present, based on cosmological simulations of the assembly of dark matter halos. Such mergers after the transformation into an early-type galaxy are presumably dissipationless ('dry'), where the increase in size is expected to be approximately proportional to the increase in mass. This model successfully reproduces the observed evolution since z ∼ 2 in the mean size and in the comoving mass density of early-type galaxies with mass M > 10 11 M sun . We conclude that

Comparative genomics reveals insights into avian genome evolution and adaptation

Science.gov (United States)

Zhang, Guojie; Li, Cai; Li, Qiye; Li, Bo; Larkin, Denis M.; Lee, Chul; Storz, Jay F.; Antunes, Agostinho; Greenwold, Matthew J.; Meredith, Robert W.; Ödeen, Anders; Cui, Jie; Zhou, Qi; Xu, Luohao; Pan, Hailin; Wang, Zongji; Jin, Lijun; Zhang, Pei; Hu, Haofu; Yang, Wei; Hu, Jiang; Xiao, Jin; Yang, Zhikai; Liu, Yang; Xie, Qiaolin; Yu, Hao; Lian, Jinmin; Wen, Ping; Zhang, Fang; Li, Hui; Zeng, Yongli; Xiong, Zijun; Liu, Shiping; Zhou, Long; Huang, Zhiyong; An, Na; Wang, Jie; Zheng, Qiumei; Xiong, Yingqi; Wang, Guangbiao; Wang, Bo; Wang, Jingjing; Fan, Yu; da Fonseca, Rute R.; Alfaro-Núñez, Alonzo; Schubert, Mikkel; Orlando, Ludovic; Mourier, Tobias; Howard, Jason T.; Ganapathy, Ganeshkumar; Pfenning, Andreas; Whitney, Osceola; Rivas, Miriam V.; Hara, Erina; Smith, Julia; Farré, Marta; Narayan, Jitendra; Slavov, Gancho; Romanov, Michael N; Borges, Rui; Machado, João Paulo; Khan, Imran; Springer, Mark S.; Gatesy, John; Hoffmann, Federico G.; Opazo, Juan C.; Håstad, Olle; Sawyer, Roger H.; Kim, Heebal; Kim, Kyu-Won; Kim, Hyeon Jeong; Cho, Seoae; Li, Ning; Huang, Yinhua; Bruford, Michael W.; Zhan, Xiangjiang; Dixon, Andrew; Bertelsen, Mads F.; Derryberry, Elizabeth; Warren, Wesley; Wilson, Richard K; Li, Shengbin; Ray, David A.; Green, Richard E.; O’Brien, Stephen J.; Griffin, Darren; Johnson, Warren E.; Haussler, David; Ryder, Oliver A.; Willerslev, Eske; Graves, Gary R.; Alström, Per; Fjeldså, Jon; Mindell, David P.; Edwards, Scott V.; Braun, Edward L.; Rahbek, Carsten; Burt, David W.; Houde, Peter; Zhang, Yong; Yang, Huanming; Wang, Jian; Jarvis, Erich D.; Gilbert, M. Thomas P.; Wang, Jun

2015-01-01

Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. The avian genome is principally characterized by its constrained size, which predominantly arose because of lineage-specific erosion of repetitive elements, large segmental deletions, and gene loss. Avian genomes furthermore show a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synteny, and chromosomal structure. Despite this pattern of conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncoding regions. These analyses reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits. PMID:25504712

Insights from advanced analytics at the Veterans Health Administration.

Science.gov (United States)

Fihn, Stephan D; Francis, Joseph; Clancy, Carolyn; Nielson, Christopher; Nelson, Karin; Rumsfeld, John; Cullen, Theresa; Bates, Jack; Graham, Gail L

2014-07-01

Health care has lagged behind other industries in its use of advanced analytics. The Veterans Health Administration (VHA) has three decades of experience collecting data about the veterans it serves nationwide through locally developed information systems that use a common electronic health record. In 2006 the VHA began to build its Corporate Data Warehouse, a repository for patient-level data aggregated from across the VHA's national health system. This article provides a high-level overview of the VHA's evolution toward "big data," defined as the rapid evolution of applying advanced tools and approaches to large, complex, and rapidly changing data sets. It illustrates how advanced analysis is already supporting the VHA's activities, which range from routine clinical care of individual patients--for example, monitoring medication administration and predicting risk of adverse outcomes--to evaluating a systemwide initiative to bring the principles of the patient-centered medical home to all veterans. The article also shares some of the challenges, concerns, insights, and responses that have emerged along the way, such as the need to smoothly integrate new functions into clinical workflow. While the VHA is unique in many ways, its experience may offer important insights for other health care systems nationwide as they venture into the realm of big data. Project HOPE—The People-to-People Health Foundation, Inc.

Sensitivity of the Hydrogen Epoch of Reionization Array and its build-out stages to one-point statistics from redshifted 21 cm observations

Science.gov (United States)

Kittiwisit, Piyanat; Bowman, Judd D.; Jacobs, Daniel C.; Beardsley, Adam P.; Thyagarajan, Nithyanandan

2018-03-01

We present a baseline sensitivity analysis of the Hydrogen Epoch of Reionization Array (HERA) and its build-out stages to one-point statistics (variance, skewness, and kurtosis) of redshifted 21 cm intensity fluctuation from the Epoch of Reionization (EoR) based on realistic mock observations. By developing a full-sky 21 cm light-cone model, taking into account the proper field of view and frequency bandwidth, utilizing a realistic measurement scheme, and assuming perfect foreground removal, we show that HERA will be able to recover statistics of the sky model with high sensitivity by averaging over measurements from multiple fields. All build-out stages will be able to detect variance, while skewness and kurtosis should be detectable for HERA128 and larger. We identify sample variance as the limiting constraint of the measurements at the end of reionization. The sensitivity can also be further improved by performing frequency windowing. In addition, we find that strong sample variance fluctuation in the kurtosis measured from an individual field of observation indicates the presence of outlying cold or hot regions in the underlying fluctuations, a feature that can potentially be used as an EoR bubble indicator.

Genome Size Dynamics and Evolution in Monocots

Directory of Open Access Journals (Sweden)

Ilia J. Leitch

2010-01-01

Full Text Available Monocot genomic diversity includes striking variation at many levels. This paper compares various genomic characters (e.g., range of chromosome numbers and ploidy levels, occurrence of endopolyploidy, GC content, chromosome packaging and organization, genome size between monocots and the remaining angiosperms to discern just how distinctive monocot genomes are. One of the most notable features of monocots is their wide range and diversity of genome sizes, including the species with the largest genome so far reported in plants. This genomic character is analysed in greater detail, within a phylogenetic context. By surveying available genome size and chromosome data it is apparent that different monocot orders follow distinctive modes of genome size and chromosome evolution. Further insights into genome size-evolution and dynamics were obtained using statistical modelling approaches to reconstruct the ancestral genome size at key nodes across the monocot phylogenetic tree. Such approaches reveal that while the ancestral genome size of all monocots was small (1C=1.9 pg, there have been several major increases and decreases during monocot evolution. In addition, notable increases in the rates of genome size-evolution were found in Asparagales and Poales compared with other monocot lineages.

Weird mammals provide insights into the evolution of mammalian sex chromosomes and dosage compensation.

Science.gov (United States)

Graves, Jennifer A Marshall

2015-12-01

The deep divergence of mammalian groups 166 and 190 million years ago (MYA) provide genetic variation to explore the evolution of DNA sequence, gene arrangement and regulation of gene expression in mammals. With encouragement from the founder of the field, Mary Lyon, techniques in cytogenetics and molecular biology were progressively adapted to characterize the sex chromosomes of kangaroos and other marsupials, platypus and echidna-and weird rodent species. Comparative gene mapping reveals the process of sex chromosome evolution from their inception 190 MYA (they are autosomal in platypus) to their inevitable end (the Y has disappeared in two rodent lineages). Our X and Y are relatively young, getting their start with the evolution of the sex-determining SRY gene, which triggered progressive degradation of the Y chromosome. Even more recently, sex chromosomes of placental mammals fused with an autosomal region which now makes up most of the Y. Exploration of gene activity patterns over four decades showed that dosage compensation via X-chromosome inactivation is unique to therian mammals, and that this whole chromosome control process is different in marsupials and absent in monotremes and reptiles, and birds. These differences can be exploited to deduce how mammalian sex chromosomes and epigenetic silencing evolved.

Systems Biology Investigations of Pseudomonas aeruginosa Evolution in Association with Human Airway Infections

DEFF Research Database (Denmark)

Pedersen, Søren Damkiær

Most knowledge about evolutionary adaptation has been gained from experimental evolution studies, in which organisms have been allowed to evolve under simple, well-defined conditions in the laboratory. While these studies have provided novel insight into the fundamental processes of evolutionary....... aeruginosa DK2 clone lineage during 200,000 generations of evolution in the CF airways from its entrance in the clinic in the 1970’ies until the end of 2010. Genetic analysis showed that the DK2 lineage between 1973 and 2007 accumulated mutations in a near-linear manner with an overall genomic signature...... included fixation of mutations in the rpoD gene encoding the principle sigma factor σ70. The findings presented in this thesis provide insight into the genetic mechanisms and evolutionary processes that shape the adaptation of bacteria colonizing complex natural environments. Increased knowledge...

Latest Pannonian and Quaternary evolution at the transition between Eastern Alps and Pannonian Basin: new insights from geophysical, sedimentological and geochronological data

Science.gov (United States)

Zámolyi, A.; Salcher, B.; Draganits, E.; Exner, U.; Wagreich, M.; Gier, S.; Fiebig, M.; Lomax, J.; Surányi, G.; Diel, M.; Zámolyi, F.

2017-07-01

The transition zone between Eastern Alps and Pannonian Basin is a key area for the investigation of the interplay between regional uplift, local tectonic subsidence and depositional environment. Our study area, the western margin of the Little Hungarian Plain, is characterized by gentle hills, plateaus and depressions, of which several are filled by lakes—including one of Austria's largest and shallowest lakes, Lake Neusiedl. Geological investigation is hampered by the scarcity of outcrops, and thus direct observation of sedimentological or structural features is difficult. Despite a long research history in the area, a consistent landscape evolution model considering all relevant constraints is lacking so far. In this study, we apply multidisciplinary methods to decipher the complex tectonic and fluvial depositional evolution of the region. Local data from shallow-lake drilling and seismic investigation are combined with regional data from industrial seismics and core data to gain new insights into the latest Pannonian (Late Miocene) and Quaternary evolution. Shallow-lake seismic data show the erosionally truncated Pannonian sediments dipping and thickening toward southeast, toward the modern depocenter of the Little Hungarian Plain. Overlying Quaternary fluvial sediments show a very similar thickening trend except for the area on the plateau north of the lake indicating ongoing subsidence in major parts of the basin. Drill cores from locations along the lake seismic lines were analyzed concerning their age, mineralogy and heavy minerals and compared with outcrop samples from the surrounding plains and the plateau to derive indications on sediment provenance. A key observation is the apparent lack of a significant gravel layer on top of the tilted Pannonian sediments beneath Lake Neusiedl. Small-scale faults can be observed in the lake seismic sections along with key sedimentary features. Significant differences of the current elevation of the top Pannonian

Brain Evolution and Human Neuropsychology: The Inferential Brain Hypothesis

Science.gov (United States)

Koscik, Timothy R.; Tranel, Daniel

2013-01-01

Collaboration between human neuropsychology and comparative neuroscience has generated invaluable contributions to our understanding of human brain evolution and function. Further cross-talk between these disciplines has the potential to continue to revolutionize these fields. Modern neuroimaging methods could be applied in a comparative context, yielding exciting new data with the potential of providing insight into brain evolution. Conversely, incorporating an evolutionary base into the theoretical perspectives from which we approach human neuropsychology could lead to novel hypotheses and testable predictions. In the spirit of these objectives, we present here a new theoretical proposal, the Inferential Brain Hypothesis, whereby the human brain is thought to be characterized by a shift from perceptual processing to inferential computation, particularly within the social realm. This shift is believed to be a driving force for the evolution of the large human cortex. PMID:22459075

Outgassing History and Escape of the Martian Atmosphere and Water Inventory

Science.gov (United States)

Lammer, Helmut; Chassefière, Eric; Karatekin, Özgür; Morschhauser, Achim; Niles, Paul B.; Mousis, Olivier; Odert, Petra; Möstl, Ute V.; Breuer, Doris; Dehant, Véronique; Grott, Matthias; Gröller, Hannes; Hauber, Ernst; Pham, Lê Binh San

2013-01-01

The evolution and escape of the martian atmosphere and the planet's water inventory can be separated into an early and late evolutionary epoch. The first epoch started from the planet's origin and lasted ˜500 Myr. Because of the high EUV flux of the young Sun and Mars' low gravity it was accompanied by hydrodynamic blow-off of hydrogen and strong thermal escape rates of dragged heavier species such as O and C atoms. After the main part of the protoatmosphere was lost, impact-related volatiles and mantle outgassing may have resulted in accumulation of a secondary CO2 atmosphere of a few tens to a few hundred mbar around ˜4-4.3 Gyr ago. The evolution of the atmospheric surface pressure and water inventory of such a secondary atmosphere during the second epoch which lasted from the end of the Noachian until today was most likely determined by a complex interplay of various nonthermal atmospheric escape processes, impacts, carbonate precipitation, and serpentinization during the Hesperian and Amazonian epochs which led to the present day surface pressure.

The evolution of nervous system patterning: insights from sea urchin development

Science.gov (United States)

Angerer, Lynne M.; Yaguchi, Shunsuke; Angerer, Robert C.; Burke, Robert D.

2011-01-01

Recent studies of the sea urchin embryo have elucidated the mechanisms that localize and pattern its nervous system. These studies have revealed the presence of two overlapping regions of neurogenic potential at the beginning of embryogenesis, each of which becomes progressively restricted by separate, yet linked, signals, including Wnt and subsequently Nodal and BMP. These signals act to specify and localize the embryonic neural fields – the anterior neuroectoderm and the more posterior ciliary band neuroectoderm – during development. Here, we review these conserved nervous system patterning signals and consider how the relationships between them might have changed during deuterostome evolution. PMID:21828090

The phenomenon of literature images transformation into musical images and paradigmal images of corresponding epochs (philosophy of history analysis

Directory of Open Access Journals (Sweden)

M. V. Masayev

2014-01-01

The author comes to the conclusion that the images of the M. A. Sholokhov’s novels «Quit Waves of Don» and «Newly­ploughed virgin soil» and short story «Destiny of the man» having become musical images of the I. I. Dzerzhinsky’s operas «Quit Waves of Don», «Newly­ploughed virgin soil», «Destiny of the man» and «Grigoriy Melekhov», turned into real paradigmal symbols of the epochs of the civil war, collectivization and the Great Patriotic War.

SARAS 2: a spectral radiometer for probing cosmic dawn and the epoch of reionization through detection of the global 21-cm signal

Science.gov (United States)

Singh, Saurabh; Subrahmanyan, Ravi; Shankar, N. Udaya; Rao, Mayuri Sathyanarayana; Girish, B. S.; Raghunathan, A.; Somashekar, R.; Srivani, K. S.

2018-04-01

The global 21-cm signal from Cosmic Dawn (CD) and the Epoch of Reionization (EoR), at redshifts z ˜ 6-30, probes the nature of first sources of radiation as well as physics of the Inter-Galactic Medium (IGM). Given that the signal is predicted to be extremely weak, of wide fractional bandwidth, and lies in a frequency range that is dominated by Galactic and Extragalactic foregrounds as well as Radio Frequency Interference, detection of the signal is a daunting task. Critical to the experiment is the manner in which the sky signal is represented through the instrument. It is of utmost importance to design a system whose spectral bandpass and additive spurious signals can be well calibrated and any calibration residual does not mimic the signal. Shaped Antenna measurement of the background RAdio Spectrum (SARAS) is an ongoing experiment that aims to detect the global 21-cm signal. Here we present the design philosophy of the SARAS 2 system and discuss its performance and limitations based on laboratory and field measurements. Laboratory tests with the antenna replaced with a variety of terminations, including a network model for the antenna impedance, show that the gain calibration and modeling of internal additive signals leave no residuals with Fourier amplitudes exceeding 2 mK, or residual Gaussians of 25 MHz width with amplitudes exceeding 2 mK. Thus, even accounting for reflection and radiation efficiency losses in the antenna, the SARAS 2 system is capable of detection of complex 21-cm profiles at the level predicted by currently favoured models for thermal baryon evolution.

Structure and tectonic evolution of the southwestern Trinidad dome, Escambray complex, Central Cuba: Insights into deformation in an accretionary wedge

Science.gov (United States)

Despaigne-Díaz, Ana Ibis; García Casco, Antonio; Cáceres Govea, Dámaso; Wilde, Simon A.; Millán Trujillo, Guillermo

2017-10-01

insights into the tectonic evolution of accretionary wedges in an intra-arc setting.

Evolution of external genitalia: insights from reptilian development.

Science.gov (United States)

Gredler, Marissa L; Larkins, Christine E; Leal, Francisca; Lewis, A Kelsey; Herrera, Ana M; Perriton, Claire L; Sanger, Thomas J; Cohn, Martin J

2014-01-01

External genitalia are found in each of the major clades of amniotes. The phallus is an intromittent organ that functions to deliver sperm into the female reproductive tract for internal fertilization. The cellular and molecular genetic mechanisms of external genital development have begun to be elucidated from studies of the mouse genital tubercle, an embryonic appendage adjacent to the cloaca that is the precursor of the penis and clitoris. Progress in this area has improved our understanding of genitourinary malformations, which are among the most common birth defects in humans, and created new opportunities for comparative studies of other taxa. External genitalia evolve rapidly, which has led to a striking diversity of anatomical forms. Within the past year, studies of external genital development in non-mammalian amniotes, including birds, lizards, snakes, alligators, and turtles, have begun to shed light on the molecular and morphogenetic mechanisms underlying the diversification of phallus morphology. Here, we review recent progress in the comparative developmental biology of external genitalia and discuss the implications of this work for understanding external genital evolution. We address the question of the deep homology (shared common ancestry) of genital structures and of developmental mechanisms, and identify new areas of investigation that can be pursued by taking a comparative approach to studying development of the external genitalia. We propose an evolutionary interpretation of hypospadias, a congenital malformation of the urethra, and discuss how investigations of non-mammalian species can provide novel perspectives on human pathologies.

The evolution of postpairing male mate choice.

Science.gov (United States)

Lyu, Nan; Servedio, Maria R; Lloyd, Huw; Sun, Yue-Hua

2017-06-01

An increasing number of empirical studies in animals have demonstrated male mate choice. However, little is known about the evolution of postpairing male choice, specifically which occurs by differential allocation of male parental care in response to female signals. We use a population genetic model to examine whether such postpairing male mate choice can evolve when males face a trade-off between parental care and extra-pair copulations (EPCs). Specifically, we assume that males allocate more effort to providing parental care when mated to preferred (signaling) females, but they are then unable to allocate additional effort to seek EPCs. We find that both male preference and female signaling can evolve in this situation, under certain conditions. First, this evolution requires a relatively large difference in parental investment between males mated to preferred versus nonpreferred females. Second, whether male choice and female signaling alleles become fixed in a population versus cycle in their frequencies depends on the additional fecundity benefits from EPCs that are gained by choosy males. Third, less costly female signals enable both signaling and choice alleles to evolve under more relaxed conditions. Our results also provide a new insight into the evolution of sexual conflict over parental care. © 2017 The Author(s). Evolution published by Wiley Periodicals, Inc. on behalf of The Society for the Study of Evolution.

New insights on the evolution of Leafy cotyledon1 (LEC1) type genes in vascular plants.

Science.gov (United States)

Cagliari, Alexandro; Turchetto-Zolet, Andreia Carina; Korbes, Ana Paula; Maraschin, Felipe Dos Santos; Margis, Rogerio; Margis-Pinheiro, Marcia

2014-01-01

NF-Y is a conserved oligomeric transcription factor found in all eukaryotes. In plants, this regulator evolved with a broad diversification of the genes coding for its three subunits (NF-YA, NF-YB and NF-YC). The NF-YB members can be divided into Leafy Cotyledon1 (LEC1) and non-LEC1 types. Here we presented a comparative genomic study using phylogenetic analyses to validate an evolutionary model for the origin of LEC-type genes in plants and their emergence from non-LEC1-type genes. We identified LEC1-type members in all vascular plant genomes, but not in amoebozoa, algae, fungi, metazoa and non-vascular plant representatives, which present exclusively non-LEC1-type genes as constituents of their NF-YB subunits. The non-synonymous to synonymous nucleotide substitution rates (Ka/Ks) between LEC1 and non-LEC1-type genes indicate the presence of positive selection acting on LEC1-type members to the fixation of LEC1-specific amino acid residues. The phylogenetic analyses demonstrated that plant LEC1-type genes are evolutionary divergent from the non-LEC1-type genes of plants, fungi, amoebozoa, algae and animals. Our results point to a scenario in which LEC1-type genes have originated in vascular plants after gene expansion in plants. We suggest that processes of neofunctionalization and/or subfunctionalization were responsible for the emergence of a versatile role for LEC1-type genes in vascular plants, especially in seed plants. LEC1-type genes besides being phylogenetic divergent also present different expression profile when compared with non-LEC1-type genes. Altogether, our data provide new insights about the LEC1 and non-LEC1 evolutionary relationship during the vascular plant evolution. Copyright © 2014 Elsevier Inc. All rights reserved.

InSight: Single Station Broadband Seismology for Probing Mars' Interior

Science.gov (United States)

Panning, Mark P.; Banerdt, W. Bruce; Beucler, Eric; Boschi, Lapo; Johnson, Catherine; Lognonne, Philippe; Mocquet, Antoine; Weber, Renee C.

2012-01-01

InSight is a proposed Discovery mission which will deliver a lander containing geophysical instrumentation, including a heat flow probe and a seismometer package, to Mars. The aim of this mission is to perform, for the first time, an in-situ investigation of the interior of a truly Earth- like planet other than our own, with the goal of understanding the formation and evolution of terrestrial planets through investigation of the interior structure and processes of Mars.

Superposed epoch analysis applied to large-amplitude travelling convection vortices

Directory of Open Access Journals (Sweden)

H. Lühr

1998-07-01

Full Text Available For the six months from 1 October 1993 to 1 April 1994 the recordings of the IMAGE magnetometer network have been surveyed in a search for large-amplitude travelling convection vortices (TCVs. The restriction to large amplitudes (>100 nT was chosen to ensure a proper detection of evens also during times of high activity. Readings of all stations of the northern half of the IMAGE network were employed to check the consistency of the ground signature with the notation of a dual-vortex structure moving in an azimuthal direction. Applying these stringent selection criteria we detected a total of 19 clear TCV events. The statistical properties of our selection resemble the expected characteristics of large-amplitude TCVs. New and unexpected results emerged from the superposed epoch analysis. TCVs tend to form during quiet intervals embedded in moderately active periods. The occurrence of events is not randomly distributed but rather shows a clustering around a few days. These clusters recur once or twice every 27 days. Within a storm cycle they show up five to seven days after the commencement. With regard to solar wind conditions, we see the events occurring in the middle of the IMF sector structure. Large-amplitude TCVs seem to require certain conditions to make solar wind transients 'geoeffective', which have the tendency to recur with the solar rotation period.Key words. Ionosphere (Aural ionosphere; Ionosphere- magnetosphere interactions · Magnetospheric Physics (current system

Insights into the Diversity of Attitudes Concerning Evolution and Creation: A Multidimensional Approach

Science.gov (United States)

Konneman, Christiane; Asshoff, Roman; Hammann, Marcus

2016-01-01

The main aim of this paper is to describe high school students' attitudes concerning evolution and creation, with a focus on (1) attitudes toward evolutionary theory, (2) attitudes toward the Biblical accounts of creation, (3) creationist beliefs, and (4) scientistic beliefs. Latent class analyses revealed seven attitude profiles in a sample of…

New insights about enzyme evolution from large scale studies of sequence and structure relationships

OpenAIRE

Babbitt, Patricia; Brown, SD; Babbitt, PC

2014-01-01

© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.Understanding how enzymes have evolved offers clues about their structure-function relationships and mechanisms. Here, we describe evolution of functionally diverse enzyme superfami

Evolution of carbonaceous chondrite parent bodies: Insights into cometary nuclei

International Nuclear Information System (INIS)

McSween, H.Y. Jr.

1989-01-01

It is thought that cometary samples will comprise the most primitive materials that are able to be sampled. Although parent body alteration of such samples would not necessarily detract from scientists' interest in them, the possibility exists that modification processes may have affected cometary nuclei. Inferences about the kinds of modifications that might be encountered can be drawn from data on the evolution of carbonaceous chondrite parent bodies. Observations suggest that, of all the classes of chondrites, these meteorites are most applicable to the study of comets. If the proportion of possible internal heat sources such as Al-26 in cometary materials are similar to those in chondrites, and if the time scale of comet accretion was fast enough to permit incorporation of live radionuclides, comets might have had early thermal histories somewhat like those of carbonaceous chondrite parent bodies

Euroconference on the appropriate modellings of galaxy evolution from their cosmological formation to their presently observable structures

CERN Document Server

Stasińska, Grażyna; Harfst, Stefan; Kroupa, Pavel; Theis, Christian; THE EVOLUTION OF GALAXIES

2003-01-01

Galaxies have a history This has become clear from recent sky surveys which have shown that distant galaxies, formed early in the life of the Universe, differ from the nearby ones New observational windows at ultraviolet, infrared and millimetric wavelengths (provided by ROSAT, IRAM, IUE, IRAS, ISO) have revealed that galaxies contain a wealth of components very hot gas, atomic hydrogen, molecules, dust, dark matter A significant advance is expected from the results of new instruments (VLT, FIRST, XMM) which will allow one to explore the most distant Universe Three Euroconferences were planned to punctuate this new epoch in galactic research, bringing together specialists in various fields of Astronomy This book contains the proceedings of the third conference and presents the actual state-of-the-art of modelling galaxy evolution

Insights from the complete chloroplast genome into the evolution of Sesamum indicum L.

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Haiyang Zhang

Full Text Available Sesame (Sesamum indicum L. is one of the oldest oilseed crops. In order to investigate the evolutionary characters according to the Sesame Genome Project, apart from sequencing its nuclear genome, we sequenced the complete chloroplast genome of S. indicum cv. Yuzhi 11 (white seeded using Illumina and 454 sequencing. Comparisons of chloroplast genomes between S. indicum and the 18 other higher plants were then analyzed. The chloroplast genome of cv. Yuzhi 11 contains 153,338 bp and a total of 114 unique genes (KC569603. The number of chloroplast genes in sesame is the same as that in Nicotiana tabacum, Vitis vinifera and Platanus occidentalis. The variation in the length of the large single-copy (LSC regions and inverted repeats (IR in sesame compared to 18 other higher plant species was the main contributor to size variation in the cp genome in these species. The 77 functional chloroplast genes, except for ycf1 and ycf2, were highly conserved. The deletion of the cp ycf1 gene sequence in cp genomes may be due either to its transfer to the nuclear genome, as has occurred in sesame, or direct deletion, as has occurred in Panax ginseng and Cucumis sativus. The sesame ycf2 gene is only 5,721 bp in length and has lost about 1,179 bp. Nucleotides 1-585 of ycf2 when queried in BLAST had hits in the sesame draft genome. Five repeats (R10, R12, R13, R14 and R17 were unique to the sesame chloroplast genome. We also found that IR contraction/expansion in the cp genome alters its rate of evolution. Chloroplast genes and repeats display the signature of convergent evolution in sesame and other species. These findings provide a foundation for further investigation of cp genome evolution in Sesamum and other higher plants.

Morphology, development, and evolution of fetal membranes and placentation in squamate reptiles.

Science.gov (United States)

Blackburn, Daniel G; Flemming, Alexander F

2009-09-15

Current studies on fetal membranes of reptiles are providing insight into three major historical transformations: evolution of the amniote egg, evolution of viviparity, and evolution of placentotrophy. Squamates (lizards and snakes) are ideal for such studies because their fetal membranes sustain embryos in oviparous species and contribute to placentas in viviparous species. Ultrastructure of the fetal membranes in oviparous corn snakes (Pituophis guttatus) shows that the chorioallantois is specialized for gas exchange and the omphalopleure, for water absorption. Transmission and scanning electron microscopic studies of viviparous thamnophine snakes (Thamnophis, Storeria) have revealed morphological specializations for gas exchange and absorption in the intra-uterine environment that represent modifications of features found in oviparous species. Thus, fetal membranes in oviparous species show morphological differentiation for distinct functions that have been recruited and enhanced under viviparous conditions. The ultimate in specialization of fetal membranes is found in viviparous skinks of South America (Mabuya) and Africa (Trachylepis, Eumecia), in which placentotrophy accounts for nearly all of the nutrients for development. Ongoing research on these lizards has revealed morphological specializations of the chorioallantoic placenta through which nutrient transfer is accomplished. In addition, African Trachylepis show an invasive form of implantation, in which uterine epithelium is replaced by invading chorionic cells. Ongoing analysis of these lizards shows how integration of multiple lines of evidence can provide insight into the evolution of developmental and reproductive specializations once thought to be confined to eutherian mammals.

New insights on equid locomotor evolution from the lumbar region of fossil horses.

Science.gov (United States)

Jones, Katrina Elizabeth

2016-04-27

The specialization of equid limbs for cursoriality is a classic case of adaptive evolution, but the role of the axial skeleton in this famous transition is not well understood. Extant horses are extremely fast and efficient runners, which use a stiff-backed gallop with reduced bending of the lumbar region relative to other mammals. This study tests the hypothesis that stiff-backed running in horses evolved in response to evolutionary increases in body size by examining lumbar joint shape from a broad sample of fossil equids in a phylogenetic context. Lumbar joint shape scaling suggests that stability of the lumbar region does correlate with size through equid evolution. However, scaling effects were dampened in the posterior lumbar region, near the sacrum, which suggests strong selection for sagittal mobility in association with locomotor-respiratory coupling near the lumbosacral joint. I hypothesize that small-bodied fossil horses may have used a speed-dependent running gait, switching between stiff-backed and flex-backed galloping as speed increased. © 2016 The Author(s).

The Brassica oleracea genome reveals the asymmetrical evolution of polyploid genomes

Science.gov (United States)

Liu, Shengyi; Liu, Yumei; Yang, Xinhua; Tong, Chaobo; Edwards, David; Parkin, Isobel A. P.; Zhao, Meixia; Ma, Jianxin; Yu, Jingyin; Huang, Shunmou; Wang, Xiyin; Wang, Junyi; Lu, Kun; Fang, Zhiyuan; Bancroft, Ian; Yang, Tae-Jin; Hu, Qiong; Wang, Xinfa; Yue, Zhen; Li, Haojie; Yang, Linfeng; Wu, Jian; Zhou, Qing; Wang, Wanxin; King, Graham J; Pires, J. Chris; Lu, Changxin; Wu, Zhangyan; Sampath, Perumal; Wang, Zhuo; Guo, Hui; Pan, Shengkai; Yang, Limei; Min, Jiumeng; Zhang, Dong; Jin, Dianchuan; Li, Wanshun; Belcram, Harry; Tu, Jinxing; Guan, Mei; Qi, Cunkou; Du, Dezhi; Li, Jiana; Jiang, Liangcai; Batley, Jacqueline; Sharpe, Andrew G; Park, Beom-Seok; Ruperao, Pradeep; Cheng, Feng; Waminal, Nomar Espinosa; Huang, Yin; Dong, Caihua; Wang, Li; Li, Jingping; Hu, Zhiyong; Zhuang, Mu; Huang, Yi; Huang, Junyan; Shi, Jiaqin; Mei, Desheng; Liu, Jing; Lee, Tae-Ho; Wang, Jinpeng; Jin, Huizhe; Li, Zaiyun; Li, Xun; Zhang, Jiefu; Xiao, Lu; Zhou, Yongming; Liu, Zhongsong; Liu, Xuequn; Qin, Rui; Tang, Xu; Liu, Wenbin; Wang, Yupeng; Zhang, Yangyong; Lee, Jonghoon; Kim, Hyun Hee; Denoeud, France; Xu, Xun; Liang, Xinming; Hua, Wei; Wang, Xiaowu; Wang, Jun; Chalhoub, Boulos; Paterson, Andrew H

2014-01-01

Polyploidization has provided much genetic variation for plant adaptive evolution, but the mechanisms by which the molecular evolution of polyploid genomes establishes genetic architecture underlying species differentiation are unclear. Brassica is an ideal model to increase knowledge of polyploid evolution. Here we describe a draft genome sequence of Brassica oleracea, comparing it with that of its sister species B. rapa to reveal numerous chromosome rearrangements and asymmetrical gene loss in duplicated genomic blocks, asymmetrical amplification of transposable elements, differential gene co-retention for specific pathways and variation in gene expression, including alternative splicing, among a large number of paralogous and orthologous genes. Genes related to the production of anticancer phytochemicals and morphological variations illustrate consequences of genome duplication and gene divergence, imparting biochemical and morphological variation to B. oleracea. This study provides insights into Brassica genome evolution and will underpin research into the many important crops in this genus. PMID:24852848

Factors Potentially Influencing Student Acceptance of Biological Evolution

Science.gov (United States)

Wiles, Jason R.

This investigation explored scientific, religious, and otherwise nonscientific factors that may influence student acceptance of biological evolution and related concepts, how students perceived these factors to have influenced their levels of acceptance of evolution and changes therein, and what patterns arose among students' articulations of how their levels of acceptance of evolution may have changed. This exploration also measured the extent to which students' levels of acceptance changed following a treatment designed to address factors identified as potentially affecting student acceptance of evolution. Acceptance of evolution was measured using the MATE instrument (Rutledge and Warden, 1999; Rutledge and Sadler, 2007) among participants enrolled in a secondary-level academic program during the summer prior to their final year of high school and as they transitioned to the post-secondary level. Student acceptance of evolution was measured to be significantly higher than pre-treatment levels both immediately following and slightly over one year after treatment. Qualitative data from informal questionnaires, from formal course evaluations, and from semi-structured interviews of students engaged in secondary level education and former students at various stages of post-secondary education confirmed that the suspected factors were perceived by participants to have influenced their levels of acceptance of evolution. Furthermore, participant reports provided insight regarding the relative effects they perceived these factors to have had on their evolution acceptance levels. Additionally, many participants reported that their science teachers in public schools had avoided, omitted, or denigrated evolution during instruction, and several of these students expressed frustration regarding what they perceived to have been a lack of education of an important scientific principle. Finally, no students expressed feelings of being offended by having been taught about

On the Evolution of the Central Density of Quiescent Galaxies

Energy Technology Data Exchange (ETDEWEB)

Tacchella, Sandro; Carollo, C. Marcella; Woo, Joanna [Department of Physics, Institute for Astronomy, ETH Zurich, CH-8093 Zurich (Switzerland); Faber, S. M.; Koo, David C. [Department of Astronomy and Astrophysics, University of California Observatories/Lick Observatory, University of California, Santa Cruz, CA (United States); Cibinel, Anna [Astronomy Centre, Department of Physics and Astronomy, University of Sussex, Brighton, BN1 9QH (United Kingdom); Dekel, Avishai [Center for Astrophysics and Planetary Science, Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel); Renzini, Alvio, E-mail: sandro.tacchella@phys.ethz.ch [INAF Osservatorio Astronomico di Padova, vicolo dellOsservatorio 5, I-35122 Padova (Italy)

2017-07-20

We investigate the origin of the evolution of the population-averaged central stellar mass density (Σ{sub 1}) of quiescent galaxies (QGs) by probing the relation between stellar age and Σ{sub 1} at z ∼ 0. We use the Zurich ENvironmental Study (ZENS), which is a survey of galaxy groups with a large fraction of satellite galaxies. QGs shape a narrow locus in the Σ{sub 1}– M {sub ⋆} plane, which we refer to as Σ{sub 1} ridgeline. Colors of ( B − I ) and ( I − J ) are used to divide QGs into three age categories: young (<2 Gyr), intermediate (2–4 Gyr), and old (>4 Gyr). At fixed stellar mass, old QGs on the Σ{sub 1} ridgeline have higher Σ{sub 1} than young QGs. This shows that galaxies landing on the Σ{sub 1} ridgeline at later epochs arrive with lower Σ{sub 1}, which drives the zeropoint of the ridgeline down with time. We compare the present-day zeropoint of the oldest population at z = 0 with the zeropoint of the quiescent population 4 Gyr back in time, at z = 0.37. These zeropoints are identical, showing that the intrinsic evolution of individual galaxies after they arrive on the Σ{sub 1} ridgeline must be negligible, or must evolve parallel to the ridgeline during this interval. The observed evolution of the global zeropoint of 0.07 dex over the last 4 Gyr is thus largely due to the continuous addition of newly quenched galaxies with lower Σ{sub 1} at later times (“progenitor bias”). While these results refer to the satellite-rich ZENS sample as a whole, our work suggests a similar age–Σ{sub 1} trend for central galaxies.

The evolution of gene expression QTL in Saccharomyces cerevisiae.

Directory of Open Access Journals (Sweden)

James Ronald

2007-08-01

Full Text Available Understanding the evolutionary forces that influence patterns of gene expression variation will provide insights into the mechanisms of evolutionary change and the molecular basis of phenotypic diversity. To date, studies of gene expression evolution have primarily been made by analyzing how gene expression levels vary within and between species. However, the fundamental unit of heritable variation in transcript abundance is the underlying regulatory allele, and as a result it is necessary to understand gene expression evolution at the level of DNA sequence variation. Here we describe the evolutionary forces shaping patterns of genetic variation for 1206 cis-regulatory QTL identified in a cross between two divergent strains of Saccharomyces cerevisiae. We demonstrate that purifying selection against mildly deleterious alleles is the dominant force governing cis-regulatory evolution in S. cerevisiae and estimate the strength of selection. We also find that essential genes and genes with larger codon bias are subject to slightly stronger cis-regulatory constraint and that positive selection has played a role in the evolution of major trans-acting QTL.

Insights from amphioxus into the evolution of vertebrate cartilage.

Directory of Open Access Journals (Sweden)

Daniel Meulemans

2007-08-01

Full Text Available Central to the story of vertebrate evolution is the origin of the vertebrate head, a problem difficult to approach using paleontology and comparative morphology due to a lack of unambiguous intermediate forms. Embryologically, much of the vertebrate head is derived from two ectodermal tissues, the neural crest and cranial placodes. Recent work in protochordates suggests the first chordates possessed migratory neural tube cells with some features of neural crest cells. However, it is unclear how and when these cells acquired the ability to form cellular cartilage, a cell type unique to vertebrates. It has been variously proposed that the neural crest acquired chondrogenic ability by recruiting proto-chondrogenic gene programs deployed in the neural tube, pharynx, and notochord. To test these hypotheses we examined the expression of 11 amphioxus orthologs of genes involved in neural crest chondrogenesis. Consistent with cellular cartilage as a vertebrate novelty, we find that no single amphioxus tissue co-expresses all or most of these genes. However, most are variously co-expressed in mesodermal derivatives. Our results suggest that neural crest-derived cartilage evolved by serial cooption of genes which functioned primitively in mesoderm.

The FGGY carbohydrate kinase family: insights into the evolution of functional specificities.

Directory of Open Access Journals (Sweden)

Ying Zhang

2011-12-01

Full Text Available Function diversification in large protein families is a major mechanism driving expansion of cellular networks, providing organisms with new metabolic capabilities and thus adding to their evolutionary success. However, our understanding of the evolutionary mechanisms of functional diversity in such families is very limited, which, among many other reasons, is due to the lack of functionally well-characterized sets of proteins. Here, using the FGGY carbohydrate kinase family as an example, we built a confidently annotated reference set (CARS of proteins by propagating experimentally verified functional assignments to a limited number of homologous proteins that are supported by their genomic and functional contexts. Then, we analyzed, on both the phylogenetic and the molecular levels, the evolution of different functional specificities in this family. The results show that the different functions (substrate specificities encoded by FGGY kinases have emerged only once in the evolutionary history following an apparently simple divergent evolutionary model. At the same time, on the molecular level, one isofunctional group (L-ribulokinase, AraB evolved at least two independent solutions that employed distinct specificity-determining residues for the recognition of a same substrate (L-ribulose. Our analysis provides a detailed model of the evolution of the FGGY kinase family. It also shows that only combined molecular and phylogenetic approaches can help reconstruct a full picture of functional diversifications in such diverse families.

Female fertility following dose-adjusted EPOCH-R chemotherapy in primary mediastinal B-cell lymphomas.

Science.gov (United States)

Gharwan, Helen; Lai, Catherine; Grant, Cliona; Dunleavy, Kieron; Steinberg, Seth M; Shovlin, Margaret; Fojo, Tito; Wilson, Wyndham H

2016-07-01

We assessed fertility/gonadal function in premenopausal women treated with dose-adjusted EPOCH-Rituximab for untreated primary mediastinal B-cell lymphoma (PMBL). Eligible patents were ≤ 50 years and premenopausal. Serial reproductive histories were obtained and hormonal assays were performed on serum samples before, at the end of treatment and 4-18 months later. Twenty-eight eligible women had a median age (range) of 31 (21-50) years and were followed a median of 7.3 years. Of 23 patients who completed a questionnaire, 19 (83%) were and four were not menstruating prior to chemotherapy. Amenorrhea developed in 12 patients during chemotherapy. At > 1-year follow-up, 14/19 (74%) patients were menstruating, all years old, and six (43%) of these patients delivered healthy children. Hormonal assays showed ovarian dysfunction during chemotherapy in all patients with varying recovery at 4-18 months after treatment. Fertility was preserved in most women with ovarian failure confined to patients > 40 years old.

Insights into the evolution of sialic acid catabolism among bacteria

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Almagro-Moreno Salvador

2009-05-01

Full Text Available Abstract Background Sialic acids comprise a family of nine-carbon amino sugars that are prevalent in mucus rich environments. Sialic acids from the human host are used by a number of pathogens as an energy source. Here we explore the evolution of the genes involved in the catabolism of sialic acid. Results The cluster of genes encoding the enzymes N-acetylneuraminate lyase (NanA, epimerase (NanE, and kinase (NanK, necessary for the catabolism of sialic acid (the Nan cluster, are confined 46 bacterial species, 42 of which colonize mammals, 33 as pathogens and 9 as gut commensals. We found a putative sialic acid transporter associated with the Nan cluster in most species. We reconstructed the phylogenetic history of the NanA, NanE, and NanK proteins from the 46 species and compared them to the species tree based on 16S rRNA. Within the NanA phylogeny, Gram-negative and Gram-positive bacteria do not form distinct clades. NanA from Yersinia and Vibrio species was most closely related to the NanA clade from eukaryotes. To examine this further, we reconstructed the phylogeny of all NanA homologues in the databases. In this analysis of 83 NanA sequences, Bacteroidetes, a human commensal group formed a distinct clade with Verrucomicrobia, and branched with the Eukaryotes and the Yersinia/Vibrio clades. We speculate that pathogens such as V. cholerae may have acquired NanA from a commensal aiding their colonization of the human gut. Both the NanE and NanK phylogenies more closely represented the species tree but numerous incidences of incongruence are noted. We confirmed the predicted function of the sialic acid catabolism cluster in members the major intestinal pathogens Salmonella enterica, Vibrio cholerae, V. vulnificus, Yersinia enterocolitica and Y. pestis. Conclusion The Nan cluster among bacteria is confined to human pathogens and commensals conferring them the ability to utilize a ubiquitous carbon source in mucus rich surfaces of the human body

THE HYDROGEN EPOCH OF REIONIZATION ARRAY DISH. II. CHARACTERIZATION OF SPECTRAL STRUCTURE WITH ELECTROMAGNETIC SIMULATIONS AND ITS SCIENCE IMPLICATIONS

International Nuclear Information System (INIS)

Ewall-Wice, Aaron; Hewitt, Jacqueline; Neben, Abraham R.; Bradley, Richard; Dickenson, Roger; Doolittle, Phillip; Egan, Dennis; Hedrick, Mike; Klima, Patricia; Deboer, David; Parsons, Aaron; Ali, Zaki S.; Cheng, Carina; Patra, Nipanjana; Dillon, Joshua S.; Aguirre, James; Bowman, Judd; Thyagarajan, Nithyanandan; Venter, Mariet; Acedo, Eloy de Lera

2016-01-01

We use time-domain electromagnetic simulations to determine the spectral characteristics of the Hydrogen Epoch of Reionization Arrays (HERA) antenna. These simulations are part of a multi-faceted campaign to determine the effectiveness of the dish’s design for obtaining a detection of redshifted 21 cm emission from the epoch of reionization. Our simulations show the existence of reflections between HERA’s suspended feed and its parabolic dish reflector that fall below -40 dB at 150 ns and, for reasonable impedance matches, have a negligible impact on HERA’s ability to constrain EoR parameters. It follows that despite the reflections they introduce, dishes are effective for increasing the sensitivity of EoR experiments at a relatively low cost. We find that electromagnetic resonances in the HERA feed’s cylindrical skirt, which is intended to reduce cross coupling and beam ellipticity, introduces significant power at large delays (-40 dB at 200 ns), which can lead to some loss of measurable Fourier modes and a modest reduction in sensitivity. Even in the presence of this structure, we find that the spectral response of the antenna is sufficiently smooth for delay filtering to contain foreground emission at line-of-sight wave numbers below k ∥ ≲ 0.2 h Mpc -1 , in the region where the current PAPER experiment operates. Incorporating these results into a Fisher Matrix analysis, we find that the spectral structure observed in our simulations has only a small effect on the tight constraints HERA can achieve on parameters associated with the astrophysics of reionization.

THE HYDROGEN EPOCH OF REIONIZATION ARRAY DISH. II. CHARACTERIZATION OF SPECTRAL STRUCTURE WITH ELECTROMAGNETIC SIMULATIONS AND ITS SCIENCE IMPLICATIONS

Energy Technology Data Exchange (ETDEWEB)

Ewall-Wice, Aaron; Hewitt, Jacqueline; Neben, Abraham R. [MIT Kavli Institute for Cosmological Physics, Cambridge, MA, 02139 (United States); Bradley, Richard; Dickenson, Roger; Doolittle, Phillip; Egan, Dennis; Hedrick, Mike; Klima, Patricia [National Radio Astronomy Observatory, Charlottesville, VA (United States); Deboer, David; Parsons, Aaron; Ali, Zaki S.; Cheng, Carina; Patra, Nipanjana; Dillon, Joshua S. [Department of Astronomy, University of California, Berkeley, CA (United States); Aguirre, James [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA (United States); Bowman, Judd; Thyagarajan, Nithyanandan [Arizona State University, School of Earth and Space Exploration, Tempe, AZ 85287 (United States); Venter, Mariet [Department of Electrical and Electronic Engineering, Stellenbosch University, Stellenbosch, SA (South Africa); Acedo, Eloy de Lera [Cavendish Laboratory, University of Cambridge, Cambridge (United Kingdom); and others

2016-11-10

We use time-domain electromagnetic simulations to determine the spectral characteristics of the Hydrogen Epoch of Reionization Arrays (HERA) antenna. These simulations are part of a multi-faceted campaign to determine the effectiveness of the dish’s design for obtaining a detection of redshifted 21 cm emission from the epoch of reionization. Our simulations show the existence of reflections between HERA’s suspended feed and its parabolic dish reflector that fall below -40 dB at 150 ns and, for reasonable impedance matches, have a negligible impact on HERA’s ability to constrain EoR parameters. It follows that despite the reflections they introduce, dishes are effective for increasing the sensitivity of EoR experiments at a relatively low cost. We find that electromagnetic resonances in the HERA feed’s cylindrical skirt, which is intended to reduce cross coupling and beam ellipticity, introduces significant power at large delays (-40 dB at 200 ns), which can lead to some loss of measurable Fourier modes and a modest reduction in sensitivity. Even in the presence of this structure, we find that the spectral response of the antenna is sufficiently smooth for delay filtering to contain foreground emission at line-of-sight wave numbers below k {sub ∥} ≲ 0.2 h Mpc{sup -1}, in the region where the current PAPER experiment operates. Incorporating these results into a Fisher Matrix analysis, we find that the spectral structure observed in our simulations has only a small effect on the tight constraints HERA can achieve on parameters associated with the astrophysics of reionization.

THE ORIGIN AND EVOLUTION OF METALLICITY GRADIENTS: PROBING THE MODE OF MASS ASSEMBLY AT z ≅ 2

International Nuclear Information System (INIS)

Jones, Tucker; Ellis, Richard S.; Richard, Johan; Jullo, Eric

2013-01-01

We present and discuss measurements of the gas-phase metallicity gradient in four gravitationally lensed galaxies at z = 2.0-2.4 based on adaptive optics-assisted imaging spectroscopy with the Keck II telescope. Three galaxies with well-ordered rotation reveal metallicity gradients with lower gas-phase metallicities at larger galactocentric radii. Two of these display gradients much steeper than found locally, while a third has one similar to that seen in local disk galaxies. The fourth galaxy exhibits complex kinematics indicative of an ongoing merger and reveals an 'inverted' gradient with lower metallicity in the central regions. By comparing our sample to similar data in the literature for lower redshift galaxies, we determine that, on average, metallicity gradients must flatten by a factor of 2.6 ± 0.9 between z = 2.2 and the present epoch. This factor is in rough agreement with the size growth of massive galaxies, suggesting that inside-out growth can account for the evolution of metallicity gradients. Since the addition of our new data provides the first indication of a coherent picture of this evolution, we develop a simple model of chemical evolution to explain the collective data. We find that metallicity gradients and their evolution can be explained by the inward radial migration of gas together with a radial variation in the mass loading factor governing the ratio of outflowing gas to the local star formation rate. Average mass loading factors of ∼< 2 are inferred from our model in good agreement with direct measurements of outflowing gas in z ≅ 2 galaxies.

First Results from the Lyman Alpha Galaxies in the Epoch of Reionization (LAGER) Survey: Cosmological Reionization at z ∼ 7

Energy Technology Data Exchange (ETDEWEB)

Zheng, Zhen-Ya; Jiang, Chunyan [CAS Key Laboratory for Research in Galaxies and Cosmology, Shanghai Astronomical Observatory, Shanghai 200030 (China); Wang, Junxian; Hu, Weida; Kong, Xu [CAS Key Laboratory for Research in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Hefei, Anhui 230026 (China); Rhoads, James; Malhotra, Sangeeta; Gonzalez, Alicia [School of Earth and Space Exploration, Arizona State University, Tempe, AZ 85287 (United States); Infante, Leopoldo; Galaz, Gaspar; Barrientos, L. Felipe [Institute of Astrophysics and Center for Astroengineering, Pontificia Universidad Catolica de Chile, Santiago 7820436 (Chile); Walker, Alistair R. [Cerro Tololo Inter-American Observatory, Casilla 603, La Serena (Chile); Jiang, Linhua [The Kavli Institute for Astronomy and Astrophysics, Peking University, Beijing 100871 (China); Hibon, Pascale [European Southern Observatory, Alonso de Cordova 3107, Casilla 19001, Santiago (Chile); Zheng, XianZhong, E-mail: zhengzy@shao.ac.cn, E-mail: linfante@astro.puc.cl, E-mail: jxw@ustc.edu.cn, E-mail: Sangeeta.Malhotra@asu.edu, E-mail: James.Rhoads@asu.edu [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

2017-06-20

We present the first results from the ongoing Lyman Alpha Galaxies in the Epoch of Reionization (LAGER) project, which is the largest narrowband survey for z ∼ 7 galaxies to date. Using a specially built narrowband filter NB964 for the superb large-area Dark Energy Camera (DECam) on the NOAO/CTIO 4 m Blanco telescope, LAGER has collected 34 hr NB964 narrowband imaging data in the 3 deg{sup 2} COSMOS field. We have identified 23 Ly α Emitter candidates at z = 6.9 in the central 2-deg{sup 2} region, where DECam and public COSMOS multi-band images exist. The resulting luminosity function (LF) can be described as a Schechter function modified by a significant excess at the bright end (four galaxies with L {sub Lyα∼} 10{sup 43.4±0.2} erg s{sup −1}). The number density at L {sub Ly} {sub α} ∼ 10{sup 43.4±0.2} erg s{sup −1} is little changed from z = 6.6, while at fainter L {sub Lyα} it is substantially reduced. Overall, we see a fourfold reduction in Ly α luminosity density from z = 5.7 to z = 6.9. Combined with a more modest evolution of the continuum UV luminosity density, this suggests a factor of ∼3 suppression of Ly α by radiative transfer through the z ∼ 7 intergalactic medium (IGM). It indicates an IGM neutral fraction of x {sub Hi} ∼ 0.4–0.6 (assuming Ly α velocity offsets of 100–200 km s{sup −1}). The changing shape of the Ly α LF between z ≲ 6.6 and z = 6.9 supports the hypothesis of ionized bubbles in a patchy reionization at z ∼ 7.

Solar-wind turbulence and shear: a superposed-epoch analysis of corotating interaction regions at 1 AU

Energy Technology Data Exchange (ETDEWEB)

Borovsky, Joseph E [Los Alamos National Laboratory; Denton, Michael H [LANCASTER UNIV.

2009-01-01

A superposed-epoch analysis of ACE and OMNI2 measurements is performed on 27 corotating interaction regions (CIRs) in 2003-2008, with the zero epoch taken to be the stream interface as determined by the maximum of the plasma vorticity. The structure of CIRs is investigated. When the flow measurements are rotated into the local-Parker-spiral coordinate system the shear is seen to be abrupt and intense, with vorticities on the order of 10{sup -5}-10{sup -4} sec{sup -1}. Converging flows perpendicular to the stream interface are seen in the local-Parker-spiral coordinate system and about half of the CIRs show a layer of divergent rebound flow away from the stream interface. Arguments indicate that any spreading of turbulence away from the region where it is produced is limited to about 10{sup 6} km, which is very small compared with the thickness of a CrR. Analysis of the turbulence across the CrRs is performed. When possible, the effects of discontinuities are removed from the data. Fluctuation amplitudes, the Alfvenicity, and the level of Alfvenic correlations all vary smoothly across the CrR. The Alfven ratio exhibits a decrease at the shear zone of the stream interface. Fourier analysis of 4.5-hr subintervals of ACE data is performed and the results are superposed averaged as an ensemble of realizations. The spectral slopes of the velocity, magnetic-field, and total-energy fluctuations vary smoothly across the CIR. The total-energy spectral slope is {approx} 3/2 in the slow and fast wind and in the CrRs. Analysis of the Elsasser inward-outward fluctuations shows a smooth transition across the CrR from an inward-outward balance in the slow wind to an outward dominance in the fast wind. A number of signatures of turbulence driving at the shear zone are sought (entropy change, turbulence amplitude, Alfvenicity, Alfven ratio, spectral slopes, in-out nature): none show evidence of driving of turbulence by shear.

FORMATION EPOCHS, STAR FORMATION HISTORIES, AND SIZES OF MASSIVE EARLY-TYPE GALAXIES IN CLUSTER AND FIELD ENVIRONMENTS AT z = 1.2: INSIGHTS FROM THE REST-FRAME ULTRAVIOLET

International Nuclear Information System (INIS)

Rettura, Alessandro; Demarco, R.; Ford, H. C.; Rosati, P.; Gobat, R.; Nonino, M.; Fosbury, R. A. E.; Menci, N.; Strazzullo, V.; Mei, S.

2010-01-01

We derive stellar masses, ages, and star formation histories (SFHs) of massive early-type galaxies in the z = 1.237 RDCS1252.9-2927 cluster and compare them with those measured in a similarly mass-selected sample of field contemporaries drawn from the Great Observatories Origin Deep Survey South Field. Robust estimates of these parameters are obtained by comparing a large grid of composite stellar population models with 8-9 band photometry in the rest-frame near-ultraviolet, optical, and IR, thus sampling the entire relevant domain of emission of the different stellar populations. Additionally, we present new, deep U-band photometry of both fields, giving access to the critical far-ultraviolet rest frame, in order to empirically constrain the dependence of the most recent star formation processes on the environment. We also analyze the morphological properties of both samples to examine the dependence of their scaling relations on their mass and environment. We find that early-type galaxies, both in the cluster and in the field, show analogous optical morphologies, follow comparable mass versus size relation, have congruent average surface stellar mass densities, and lie on the same Kormendy relation. We also show that a fraction of early-type galaxies in the field employ longer timescales, τ, to assemble their mass than their cluster contemporaries. Hence, we conclude that while the formation epoch of early-type galaxies only depends on their mass, the environment does regulate the timescales of their SFHs. Our deep U-band imaging strongly supports this conclusion. We show that cluster galaxies are at least 0.5 mag fainter than their field contemporaries of similar mass and optical-to-infrared colors, implying that the last episode of star formation must have happened more recently in the field than in the cluster.

Xenia: A Probe of Cosmic Chemical Evolution

Science.gov (United States)

Kouveliotou, Chryssa; Piro, L.

2008-01-01

Xenia is a concept study for a medium-size astrophysical cosmology mission addressing the Cosmic Origins key objective of NASA's Science Plan. The fundamental goal of this objective is to understand the formation and evolution of structures on various scales from the early Universe to the present time (stars, galaxies and the cosmic web). Xenia will use X-and y-ray monitoring and wide field X-ray imaging and high-resolution spectroscopy to collect essential information from three major tracers of these cosmic structures: the Warm Hot Intergalactic Medium (WHIM), Galaxy Clusters and Gamma Ray Bursts (GRBs). Our goal is to trace the chemo-dynamical history of the ubiquitous warm hot diffuse baryon component in the Universe residing in cosmic filaments and clusters of galaxies up to its formation epoch (at z =0-2) and to map star formation and galaxy metal enrichment into the re-ionization era beyond z 6. The concept of Xenia (Greek for "hospitality") evolved in parallel with the Explorer of Diffuse Emission and GRB Explosions (EDGE), a mission proposed by a multinational collaboration to the ESA Cosmic Vision 2015. Xenia incorporates the European and Japanese collaborators into a U.S. led mission that builds on the scientific objectives and technological readiness of EDGE.

Xenia: A Probe of Cosmic Chemical Evolution

Science.gov (United States)

Kouveliotou, Chryssa; Piro, L.; Xenia Collaboration

2008-03-01

Xenia is a concept study for a medium-size astrophysical cosmology mission addressing the Cosmic Origins key objective of NASA's Science Plan. The fundamental goal of this objective is to understand the formation and evolution of structures on various scales from the early Universe to the present time (stars, galaxies and the cosmic web). Xenia will use X-and γ-ray monitoring and wide field X-ray imaging and high-resolution spectroscopy to collect essential information from three major tracers of these cosmic structures: the Warm Hot Intergalactic Medium (WHIM), Galaxy Clusters and Gamma Ray Bursts (GRBs). Our goal is to trace the chemo-dynamical history of the ubiquitous warm hot diffuse baryon component in the Universe residing in cosmic filaments and clusters of galaxies up to its formation epoch (at z =0-2) and to map star formation and galaxy metal enrichment into the re-ionization era beyond z 6. The concept of Xenia (Greek for "hospitality") evolved in parallel with the Explorer of Diffuse Emission and GRB Explosions (EDGE), a mission proposed by a multinational collaboration to the ESA Cosmic Vision 2015. Xenia incorporates the European and Japanese collaborators into a U.S. led mission that builds on the scientific objectives and technological readiness of EDGE.

A PRECISION MULTI-BAND TWO-EPOCH PHOTOMETRIC CATALOG OF 44 MILLION SOURCES IN THE NORTHERN SKY FROM A COMBINATION OF THE USNO-B AND SLOAN DIGITAL SKY SURVEY CATALOGS

International Nuclear Information System (INIS)

Madsen, G. J.; Gaensler, B. M.

2013-01-01

A key science driver for the next generation of wide-field optical and radio surveys is the exploration of the time variable sky. These surveys will have unprecedented sensitivity and areal coverage, but will be limited in their ability to detect variability on time scales longer than the lifetime of the surveys. We present a new precision, multi-epoch photometric catalog that spans 60 yr by combining the US Naval Observatory-B (USNO-B) and Sloan Digital Sky Survey (SDSS) Data Release 9 (DR9) catalogs. We recalibrate the photometry of the original USNO-B catalog and create a catalog with two epochs of photometry in up to five different bands for 43,647,887 optical point sources that lie in the DR9 footprint of the northern sky. The recalibrated objects span a magnitude range 14 ≲ m ≲ 20 and are accurate to ≈0.1 mag. We minimize the presence of spurious objects and those with inaccurate magnitudes by identifying and removing several sources of systematic errors in the two originating catalogs, with a focus on spurious objects that exhibit large apparent magnitude variations. After accounting for these effects, we find ≈250,000 stars and quasars that show significant (≥4σ) changes in brightness between the USNO-B and SDSS DR9 epochs. We discuss the historical value of the catalog and its application to the study of long time scale, large amplitude variable stars and quasars

The Egyptian geomagnetic reference field to the Epoch, 2010.0

Science.gov (United States)

Deebes, H. A.; Abd Elaal, E. M.; Arafa, T.; Lethy, A.; El Emam, A.; Ghamry, E.; Odah, H.

2017-06-01

The present work is a compilation of two tasks within the frame of the project ;Geomagnetic Survey & Detailed Geomagnetic Measurements within the Egyptian Territory; funded by the ;Science and Technology Development Fund agency (STDF);. The National Research Institute of Astronomy and Geophysics (NRIAG), has conducted a new extensive land geomagnetic survey that covers the whole Egyptian territory. The field measurements have been done at 3212 points along all the asphalted roads, defined tracks, and ill-defined tracks in Egypt; with total length of 11,586 km. In the present work, the measurements cover for the first time new areas as: the southern eastern borders of Egypt including Halayeb and Shlatin, the Quattara depresion in the western desert, and the new roads between Farafra and Baharia oasis. Also marine geomagnetic survey have been applied for the first time in Naser lake. Misallat and Abu-Simble geomagnetic observatories have been used to reduce the field data to the Epoch 2010. During the field measurements, whenever possible, the old stations occupied by the previous observers have been re-occupied to determine the secular variations at these points. The geomagnetic anomaly maps, the normal geomagnetic field maps with their corresponding secular variation maps, the normal geomagnetic field equations of the geomagnetic elements (EGRF) and their corresponding secular variations equations, are outlined. The anomalous sites, as discovered from the anomaly maps are, only, mentioned. In addition, a correlation between the International Geomagnetic Reference Field (IGRF) 2010.0 and the Egyptian Geomagnetic Reference Field (EGRF) 2010 is indicated.

Luminescence in Primordial Helium Lines at the Pre-recombination Epoch

Science.gov (United States)

Dubrovich, V. K.; Grachev, S. I.

2018-04-01

The formation of luminescent subordinate He I lines by the absorption of radiation from a source in lines of the main He I series in an expanding Universe is considered. A burst of radiation in continuum is assumed to occur at some instant of time corresponding to redshift z 0. This radiation is partially absorbed at different z < z 0 in lines of the main He I series (different pumping channels) and then is partially converted into radiation in subordinate lines. If ν ik is the laboratory transition frequency of some subordinate line emerging at some z, then at the present epoch its frequency will be ν = ν ik /(1 + z). The quantum yield, i.e., the number of photons emitted in the subordinate line per initial excited atom, has been calculated for different z (and, consequently, for different ν). Several pumping channels have been considered. We show that the luminescent lines can be both emission and absorption ones; the same line can be an emission one for one of the pumping channels and an absorption one for another. For example, the 1s2s-1s2p (1S-1P*) line is an emission one for the 1s2-1s2p pumping and an absorption one for the 1s2-1s3p pumping. We show that in the frequency range 30-80 GHz the total quantum yield for the first and second of the above channels can reach +50 and -50%, respectively.

Chemical effects of ionizing radiation and sonic energy in the context of chemical evolution

International Nuclear Information System (INIS)

Negron Mendoza, A.; Albarran, G.

1992-01-01

Ionizing radiation and sonic energy are considered as sources for chemical evolution processes. These sources have still a modest place in the interdisciplinary approach for the prebiological synthesis of organic compounds. Studies in Radiation Chemistry and Sonochemistry can provide a deeper insight into the chemical processes that may have importance for prebiotic chemistry. The present work concerns the analysis of some chemical reactions induced by ionizing radiation or cavitation in aqueous media that may be relevant to chemical evolution studies. (author)

Insights on landscape evolution and climatic forcing on Titan

Science.gov (United States)

Lucas, A.; Daudon, C.; Rodriguez, S.; Cornet, T.; Perron, J. T.

2017-12-01

The landscapes of Titan were observed for nearly 13 years by the Cassini spacecraft and Huygens probe. With dunes, mountains, seas, lakes, rivers..., the great morphological variety observed testifies to the geological richness that Titan shares with the Earth. In this study, we combine analysis of radar and hyperspectral data provided by the Cassini-Huygens mission, with models of valley and river network evolution to better understand the processes at work that sculpt these familiar landscapes. We develop quantitative criteria for comparing 3D morphologies obtained by numerical simulation with those derived for Titan by photogrammetry. These criteria are validated on Earth's landscapes. We simulate morphologies similar to those observed and show that landscapes at the equator and poles are mainly controlled by river incision and mass wasting such as landslides for which we quantify their respective contribution. Subsequently, we relate modeling to precipitation rates of methane and show values that are to be compared with general circulation model predictions (GCM). Our results also show a very young age of formation of the observed morphologies, less than a few million years. Finally, we provide new constraints on current amplitude of the tidal effects and organic precipitation rates from atmosphere chemistry.

2016 Mars Insight Mission Design and Navigation

Science.gov (United States)

Abilleira, Fernando; Frauenholz, Ray; Fujii, Ken; Wallace, Mark; You, Tung-Han

2014-01-01

Scheduled for a launch in the 2016 Earth to Mars opportunity, the Interior Exploration using Seismic Investigations, Geodesy, and Heat Transport (InSight) Mission will arrive to Mars in late September 2016 with the primary objective of placing a science lander on the surface of the Red Planet followed by the deployment of two science instruments to investigate the fundamental processes of terrestrial planet formation and evolution. In order to achieve a successful landing, the InSight Project has selected a launch/arrival strategy that satisfies the following key and driving requirements: (1) Deliver a total launch mass of 727 kg, (2) target a nominal landing site with a cumulative Delta V99 less than 30 m/s, and (3) approach EDL with a V-infinity upper limit of 3.941 km/s and (4) an entry flight-path angle (EFPA) of -12.5 +/- 0.26 deg, 3-sigma; the InSight trajectories have been designed such that they (5) provide UHF-band communications via Direct-To-Earth and MRO from Entry through landing plus 60 s, (6) with injection aimpoints biased away from Mars such that the probability of the launch vehicle upper stage impacting Mars is less than 1.0 X 10(exp 4) for fifty years after launch, and (7) non-nominal impact probabilities due to failure during the Cruise phase less than 1.0 X 10(exp 2).

Evolution: Tracing the origins of centrioles, cilia, and flagella.

Science.gov (United States)

Carvalho-Santos, Zita; Azimzadeh, Juliette; Pereira-Leal, José B; Bettencourt-Dias, Mónica

2011-07-25

Centrioles/basal bodies (CBBs) are microtubule-based cylindrical organelles that nucleate the formation of centrosomes, cilia, and flagella. CBBs, cilia, and flagella are ancestral structures; they are present in all major eukaryotic groups. Despite the conservation of their core structure, there is variability in their architecture, function, and biogenesis. Recent genomic and functional studies have provided insight into the evolution of the structure and function of these organelles.

The evolution of pathogenic trypanosomes

Directory of Open Access Journals (Sweden)

Jamie R. Stevens

Full Text Available In the absence of a fossil record, the evolution of protozoa has until recently largely remained a matter for speculation. However, advances in molecular methods and phylogenetic analysis are now allowing interpretation of the "history written in the genes". This review focuses on recent progress in reconstruction of trypanosome phylogeny based on molecular data from ribosomal RNA, the miniexon and protein-coding genes. Sufficient data have now been gathered to demonstrate unequivocally that trypanosomes are monophyletic; the phylogenetic trees derived can serve as a framework to reinterpret the biology, taxonomy and present day distribution of trypanosome species, providing insights into the coevolution of trypanosomes with their vertebrate hosts and vectors. Different methods of dating the divergence of trypanosome lineages give rise to radically different evolutionary scenarios and these are reviewed. In particular, the use of one such biogeographically based approach provides new insights into the coevolution of the pathogens, Trypanosoma brucei and Trypanosoma cruzi, with their human hosts and the history of the diseases with which they are associated.

Mitochondrial genome evolution in the Saccharomyces sensu stricto complex.

Science.gov (United States)

Ruan, Jiangxing; Cheng, Jian; Zhang, Tongcun; Jiang, Huifeng

2017-01-01

Exploring the evolutionary patterns of mitochondrial genomes is important for our understanding of the Saccharomyces sensu stricto (SSS) group, which is a model system for genomic evolution and ecological analysis. In this study, we first obtained the complete mitochondrial sequences of two important species, Saccharomyces mikatae and Saccharomyces kudriavzevii. We then compared the mitochondrial genomes in the SSS group with those of close relatives, and found that the non-coding regions evolved rapidly, including dramatic expansion of intergenic regions, fast evolution of introns and almost 20-fold higher rearrangement rates than those of the nuclear genomes. However, the coding regions, and especially the protein-coding genes, are more conserved than those in the nuclear genomes of the SSS group. The different evolutionary patterns of coding and non-coding regions in the mitochondrial and nuclear genomes may be related to the origin of the aerobic fermentation lifestyle in this group. Our analysis thus provides novel insights into the evolution of mitochondrial genomes.

Genome sequence analysis of the model grass Brachypodium distachyon: insights into grass genome evolution

Energy Technology Data Exchange (ETDEWEB)

Schulman, Al

2009-08-09

Three subfamilies of grasses, the Erhardtoideae (rice), the Panicoideae (maize, sorghum, sugar cane and millet), and the Pooideae (wheat, barley and cool season forage grasses) provide the basis of human nutrition and are poised to become major sources of renewable energy. Here we describe the complete genome sequence of the wild grass Brachypodium distachyon (Brachypodium), the first member of the Pooideae subfamily to be completely sequenced. Comparison of the Brachypodium, rice and sorghum genomes reveals a precise sequence- based history of genome evolution across a broad diversity of the grass family and identifies nested insertions of whole chromosomes into centromeric regions as a predominant mechanism driving chromosome evolution in the grasses. The relatively compact genome of Brachypodium is maintained by a balance of retroelement replication and loss. The complete genome sequence of Brachypodium, coupled to its exceptional promise as a model system for grass research, will support the development of new energy and food crops

On the asymmetric evolution of the perihelion distances of near-Earth Jupiter family comets around the discovery time

Science.gov (United States)

Sosa, A.; Fernández, J. A.; Pais, P.

2012-12-01

We study the dynamical evolution of the near-Earth Jupiter family comets (NEJFCs) that came close to or crossed the Earth's orbit at the epoch of their discovery (perihelion distances qdisc time evolution of the mean perihelion distance bar{q} of the NEJFCs at the discovery time of each comet (taken as t = 0) and a past-future asymmetry of bar{q} in an interval -1000 yr, +1000 yr centred on t = 0, confirming previous results. The asymmetry indicates that there are more comets with greater q in the past than in the future. For comparison purposes, we also analysed the population of near-Earth asteroids in cometary orbits (defined as those with aphelion distances Q > 4.5 AU) and with absolute magnitudes H time a large sample of fictitious comets, cloned from the observed NEJFCs, over a 20 000 yr time interval and started the integration before the comet's discovery time, when it had a perihelion distance q > 2 AU. By assuming that NEJFCs are mostly discovered when they decrease their perihelion distances below a certain threshold qthre = 1.05 AU for the first time during their evolution, we were able to reproduce the main features of the observed bar{q} evolution in the interval [-1000, 1000] yr with respect to the discovery time. Our best fits indicate that 40% of the population of NEJFCs would be composed of young, fresh comets that entered the region q spending at least 3000 yr in the q family comets (JFCs).

INFRARED CONTINUUM AND LINE EVOLUTION OF THE EQUATORIAL RING AROUND SN 1987A

Energy Technology Data Exchange (ETDEWEB)

Arendt, Richard G. [CRESST/UMBC (United States); Dwek, Eli [Observational Cosmology Lab, Code 665, NASA/GSFC, Greenbelt, MD 20771 (United States); Bouchet, Patrice [Laboratoire AIM Paris-Saclay, CEA-IRFU/SAp, CNRS, Université Paris Diderot, F-91191 Gif-sur-Yvette (France); Danziger, I. John [INAF-Osservatorio Astronomico di Trieste, via G.B. Tiepolo 11, I-34143 Trieste (Italy); Frank, Kari A. [Department of Astronomy and Astrophysics, Pennsylvania State University, University Park, PA 16802 (United States); Gehrz, Robert D.; Woodward, Charles E. [Minnesota Institute for Astrophysics, School of Physics and Astronomy, University of Minnesota, 116 Church Street, SE, Minneapolis, MN 55455 (United States); Park, Sangwook, E-mail: richard.g.arendt@nasa.gov [Department of Physics, University of Texas at Arlington, Arlington, TX 76019 (United States)

2016-03-15

Spitzer observations of SN 1987A have now spanned more than a decade. Since day ∼4000, mid-infrared (mid-IR) emission has been dominated by that from shock-heated dust in the equatorial ring (ER). From 6000 to 8000 days after the explosion, Spitzer observations included broadband photometry at 3.6–24 μm, and low and moderate resolution spectroscopy at 5–35 μm. Here we present later Spitzer observations, through day 10,377, which include only the broadband measurements at 3.6 and 4.5 μm. These data show that the 3.6 and 4.5 μm brightness has clearly begun to fade after day ∼8500, and no longer tracks the X-ray emission as well as it did at earlier epochs. This can be explained by the destruction of the dust in the ER on timescales shorter than the cooling time for the shocked gas. We find that the evolution of the late time IR emission is also similar to the now fading optical emission. We provide the complete record of the IR emission lines, as seen by Spitzer prior to day 8000. The past evolution of the gas as seen by the IR emission lines seems largely consistent with the optical emission, although the IR [Fe ii] and [Si ii] lines show different, peculiar velocity structures.

Black hole-galaxy co-evolution in the Mufasa simulations

Science.gov (United States)

Dave, Romeel; Angles-Alcazar, Daniel

2017-08-01

The Mufasa simulations are large-scale cosmological and zoom simulations of galaxy formation that employ novel state of the art modules for star formation and feedback physics, resulting in very good agreement with many key galaxy observables over most of cosmic time. We have recently included black hole growth and feedback using the torque-limited accretion model, which has several advantages over the commonly-used Bondi accretion. We also include AGN feedback using a BAL mode at high Eddington rates and low black hole masses, and a jet mode at low Eddington rates that successfully quenches galaxies. In this talk I will describe preliminary results of the AGN population and its evolution over cosmic time within our new simulations, including cosmological simulations of the general black hole population as well as zoom simulations targeting massive galaxies, with a focus on understanding the co-growth of black holes and galaxies as a function of mass, environment, and cosmic epoch. I will also discuss multi-wavelength approaches to testing and constraining our black hole model in particular using upcoming X-ray and radio facilities such as Lynx and the SKA.

ORIGIN: Metal Creation and Evolution from the Cosmic Dawn

CERN Document Server

Herder, Jan-Willem den; Ohashi, Takaya; Kouveliotou, Chryssa; Hartmann, Dieter H.; Kaastra, Jelle S.; Amati, L.; Andersen, M.I.; Arnaud, M.; Attéia, J.-L.; Bandler, S.; Barbera, M.; Barcons, X.; Barthelmy, S.; Basa, S.; Basso, S.; Boer, M.; Branchini, E.; Branduardi-Raymont, G.; Borgani, S.; Boyarsky, A.; Brunetti, G.; Budtz-Jorgensen, C.; Burrows, D.; Butler, N.; Campana, S.; Caroli, E.; Ceballos, M.; Christensen, F.; Churazov, E.; Comastri, A.; Colasanti, L.; Cole, R.; Content, R.; Corsi, A.; Costantini, E.; Conconi, P.; Cusumano, G.; de Plaa, J.; De Rosa, A.; Del Santo, M.; Di Cosimo, S.; De Pasquale, M.; Doriese, R.; Ettori, S.; Evans, P.; Ezoe, Y.; Ferrari, L.; Finger, H.; Figueroa-Feliciano, T.; Friedrich, P.; Fujimoto, R.; Furuzawa, A.; Fynbo, J.; Gatti, F.; Galeazzi, M.; Gehrels, N.; Gendre, B.; Ghirlanda, G.; Ghisellini, G.; Gilfanov, M.; Giommi, P.; Girardi, M.; Grindlay, J.; Cocchi, M.; Godet, O.; Guedel, M.; Haardt, F.; den Hartog, R.; Hepburn, I.; Hermsen, W.; Hjorth, J.; Hoekstra, H.; Holland, A.; Hornstrup, A.; van der Horst, A.; Hoshino, A.; in 't Zand, J.; Irwin, K.; Ishisaki, Y.; Jonker, P.; Kitayama, T.; Kawahara, H.; Kawai, N.; Kelley, R.; Kilbourne, C.; de Korte, P.; Kusenko, A.; Kuvvetli, I.; Labanti, M.; Macculi, C.; Maiolino, R.; Hesse, M. Mas; Matsushita, K.; Mazzotta, P.; McCammon, D.; Méndez, M.; Mignani, R.; Mineo, T.; Mitsuda, K.; Mushotzky, R.; Molendi, S.; Moscardini, L.; Natalucci, L.; Nicastro, F.; O'Brien, P.; Osborne, J.; Paerels, F.; Page, M.; Paltani, S.; Pedersen, K.; Perinati, E.; Ponman, T.; Pointecouteau, E.; Predehl, P.; Porter, S.; Rasmussen, A.; Rauw, G.; Röttgering, H.; Roncarelli, M.; Rosati, P.; Quadrini, E.; Ruchayskiy, O.; Salvaterra, R.; Sasaki, S.; Sato, K.; Savaglio, S.; Schaye, J.; Sciortino, S.; Shaposhnikov, M.; Sharples, R.; Shinozaki, K.; Spiga, D.; Sunyaev, R.; Suto, Y.; Takei, Y.; Tanvir, N.; Tashiro, M.; Tamura, T.; Tawara, Y.; Troja, E.; Tsujimoto, M.; Tsuru, T.; Ubertini, P.; Ullom, J.; Ursino, E.; Verbunt, F.; van de Voort, F.; Viel, M.; Wachter, S.; Watson, D.; Weisskopf, M.; Werner, N.; White, N.; Willingale, R.; Wijers, R.; Yamasaki, N.; Yoshikawa, K.; Zane, S.

2011-01-01

ORIGIN is a proposal for the M3 mission call of ESA aimed at the study of metal creation from the epoch of cosmic dawn. Using high-spectral resolution in the soft X-ray band, ORIGIN will be able to identify the physical conditions of all abundant elements between C and Ni to red-shifts of z=10, and beyond. The mission will answer questions such as: When were the first metals created? How does the cosmic metal content evolve? Where do most of the metals reside in the Universe? What is the role of metals in structure formation and evolution? To reach out to the early Universe ORIGIN will use Gamma-Ray Bursts (GRBs) to study their local environments in their host galaxies. This requires the capability to slew the satellite in less than a minute to the GRB location. By studying the chemical composition and properties of clusters of galaxies we can extend the range of exploration to lower redshifts (z ~ 0.2). For this task we need a high-resolution spectral imaging instrument with a large field of view. Using the ...

Long-term climate change: the evolution of shield surface boundary conditions

International Nuclear Information System (INIS)

Peltier, W.R.

2007-01-01

The Earths surface during the Pleistocene epoch has been repeatedly subjected to glacial cycles that have markedly influenced both the landscape and surface boundary conditions that, in part, governed past evolution of deep-seated Shield groundwater flow domains. As part of the Deep Geologic Repository Technology Programme simulations of the last Laurentide glacial episode have been undertaken with the University of Toronto Glacial System Model (GSM). The purpose of these simulations is to yield constrained predictions of the magnitude and time rate of change of peri-glacial, glacial and boreal regimes that have perturbed Shield flow domains in the geologic past. A detailed model of long timescale climate change has been developed, which is able to make useful predictions of the process of continental glaciation and deglaciation that has occurred in the past due to the small changes in the effective intensity of the Sun at the location of the Earth caused by gravitational many body effects in Solar System evolution. Based upon the success of this model we are able to assert that we have demonstrated a basic understanding of why this process has continually recurred in the past on a timescale of approximately 100 000 years. Continuing work with the Glacial Systems Model and efforts to provide explicit linkage to numerical analyses of sub-surface hydrology are beginning to yield a new understanding of groundwater flow system evolution and response to glacial perturbations. In so doing this understanding is not only providing a reasoned basis on which to examine issues of geosphere stability as relevant to the safety of a hypothetical repository for used nuclear fuel in Shield terrain, but is also offering an improved basis for the integrated interpretation of multi-disciplinary geo-scientific data necessary for development of a descriptive geosphere model that is seen as fundamental to the repository Safety Case. (author)

Inflow, Outflow, Yields, and Stellar Population Mixing in Chemical Evolution Models

Energy Technology Data Exchange (ETDEWEB)

Andrews, Brett H. [PITT PACC, Department of Physics and Astronomy, University of Pittsburgh, Pittsburgh, PA 15260 (United States); Weinberg, David H.; Schönrich, Ralph; Johnson, Jennifer A., E-mail: andrewsb@pitt.edu [Department of Astronomy, The Ohio State University, 140 West 18th Avenue, Columbus, OH 43210 (United States)

2017-02-01

Chemical evolution models are powerful tools for interpreting stellar abundance surveys and understanding galaxy evolution. However, their predictions depend heavily on the treatment of inflow, outflow, star formation efficiency (SFE), the stellar initial mass function, the SN Ia delay time distribution, stellar yields, and stellar population mixing. Using flexCE, a flexible one-zone chemical evolution code, we investigate the effects of and trade-offs between parameters. Two critical parameters are SFE and the outflow mass-loading parameter, which shift the knee in [O/Fe]–[Fe/H] and the equilibrium abundances that the simulations asymptotically approach, respectively. One-zone models with simple star formation histories follow narrow tracks in [O/Fe]–[Fe/H] unlike the observed bimodality (separate high- α and low- α sequences) in this plane. A mix of one-zone models with inflow timescale and outflow mass-loading parameter variations, motivated by the inside-out galaxy formation scenario with radial mixing, reproduces the two sequences better than a one-zone model with two infall epochs. We present [X/Fe]–[Fe/H] tracks for 20 elements assuming three different supernova yield models and find some significant discrepancies with solar neighborhood observations, especially for elements with strongly metallicity-dependent yields. We apply principal component abundance analysis to the simulations and existing data to reveal the main correlations among abundances and quantify their contributions to variation in abundance space. For the stellar population mixing scenario, the abundances of α -elements and elements with metallicity-dependent yields dominate the first and second principal components, respectively, and collectively explain 99% of the variance in the model. flexCE is a python package available at https://github.com/bretthandrews/flexCE.

Inflow, Outflow, Yields, and Stellar Population Mixing in Chemical Evolution Models

International Nuclear Information System (INIS)

Andrews, Brett H.; Weinberg, David H.; Schönrich, Ralph; Johnson, Jennifer A.

2017-01-01

Chemical evolution models are powerful tools for interpreting stellar abundance surveys and understanding galaxy evolution. However, their predictions depend heavily on the treatment of inflow, outflow, star formation efficiency (SFE), the stellar initial mass function, the SN Ia delay time distribution, stellar yields, and stellar population mixing. Using flexCE, a flexible one-zone chemical evolution code, we investigate the effects of and trade-offs between parameters. Two critical parameters are SFE and the outflow mass-loading parameter, which shift the knee in [O/Fe]–[Fe/H] and the equilibrium abundances that the simulations asymptotically approach, respectively. One-zone models with simple star formation histories follow narrow tracks in [O/Fe]–[Fe/H] unlike the observed bimodality (separate high- α and low- α sequences) in this plane. A mix of one-zone models with inflow timescale and outflow mass-loading parameter variations, motivated by the inside-out galaxy formation scenario with radial mixing, reproduces the two sequences better than a one-zone model with two infall epochs. We present [X/Fe]–[Fe/H] tracks for 20 elements assuming three different supernova yield models and find some significant discrepancies with solar neighborhood observations, especially for elements with strongly metallicity-dependent yields. We apply principal component abundance analysis to the simulations and existing data to reveal the main correlations among abundances and quantify their contributions to variation in abundance space. For the stellar population mixing scenario, the abundances of α -elements and elements with metallicity-dependent yields dominate the first and second principal components, respectively, and collectively explain 99% of the variance in the model. flexCE is a python package available at https://github.com/bretthandrews/flexCE.

Practical aspects of protein co-evolution.

Science.gov (United States)

Ochoa, David; Pazos, Florencio

2014-01-01

Co-evolution is a fundamental aspect of Evolutionary Theory. At the molecular level, co-evolutionary linkages between protein families have been used as indicators of protein interactions and functional relationships from long ago. Due to the complexity of the problem and the amount of genomic data required for these approaches to achieve good performances, it took a relatively long time from the appearance of the first ideas and concepts to the quotidian application of these approaches and their incorporation to the standard toolboxes of bioinformaticians and molecular biologists. Today, these methodologies are mature (both in terms of performance and usability/implementation), and the genomic information that feeds them large enough to allow their general application. This review tries to summarize the current landscape of co-evolution-based methodologies, with a strong emphasis on describing interesting cases where their application to important biological systems, alone or in combination with other computational and experimental approaches, allowed getting new insight into these.

Trace elements at the intersection of marine biological and geochemical evolution

Science.gov (United States)

Robbins, Leslie J.; Lalonde, Stefan V.; Planavsky, Noah J.; Partin, Camille A.; Reinhard, Christopher T.; Kendall, Brian; Scott, Clinton T.; Hardisty, Dalton S.; Gill, Benjamin C.; Alessi, Daniel S.; Dupont, Christopher L.; Saito, Mak A.; Crowe, Sean A.; Poulton, Simon W.; Bekker, Andrey; Lyons, Timothy W.; Konhauser, Kurt O.

2016-01-01

Life requires a wide variety of bioessential trace elements to act as structural components and reactive centers in metalloenzymes. These requirements differ between organisms and have evolved over geological time, likely guided in some part by environmental conditions. Until recently, most of what was understood regarding trace element concentrations in the Precambrian oceans was inferred by extrapolation, geochemical modeling, and/or genomic studies. However, in the past decade, the increasing availability of trace element and isotopic data for sedimentary rocks of all ages has yielded new, and potentially more direct, insights into secular changes in seawater composition – and ultimately the evolution of the marine biosphere. Compiled records of many bioessential trace elements (including Ni, Mo, P, Zn, Co, Cr, Se, and I) provide new insight into how trace element abundance in Earth's ancient oceans may have been linked to biological evolution. Several of these trace elements display redox-sensitive behavior, while others are redox-sensitive but not bioessential (e.g., Cr, U). Their temporal trends in sedimentary archives provide useful constraints on changes in atmosphere-ocean redox conditions that are linked to biological evolution, for example, the activity of oxygen-producing, photosynthetic cyanobacteria. In this review, we summarize available Precambrian trace element proxy data, and discuss how temporal trends in the seawater concentrations of specific trace elements may be linked to the evolution of both simple and complex life. We also examine several biologically relevant and/or redox-sensitive trace elements that have yet to be fully examined in the sedimentary rock record (e.g., Cu, Cd, W) and suggest several directions for future studies.

Evolution of the Proximal Sealing Rings of the Anaconda Stent-Graft After Endovascular Aneurysm Repair

NARCIS (Netherlands)

Koenrades, Maaike A.; Klein, Almar; Leferink, Anne M.; Slump, Cornelis H.; Geelkerken, Robert H.

2018-01-01

Purpose: To provide insight into the evolution of the saddle-shaped proximal sealing rings of the Anaconda stent-graft after endovascular aneurysm repair (EVAR). Methods: Eighteen abdominal aortic aneurysm patients were consecutively enrolled in a single-center, prospective, observational cohort

Centromere Destiny in Dicentric Chromosomes: New Insights from the Evolution of Human Chromosome 2 Ancestral Centromeric Region.

Science.gov (United States)

Chiatante, Giorgia; Giannuzzi, Giuliana; Calabrese, Francesco Maria; Eichler, Evan E; Ventura, Mario

2017-07-01

Dicentric chromosomes are products of genomic rearrangements that place two centromeres on the same chromosome. Due to the presence of two primary constrictions, they are inherently unstable and overcome their instability by epigenetically inactivating and/or deleting one of the two centromeres, thus resulting in functionally monocentric chromosomes that segregate normally during cell division. Our understanding to date of dicentric chromosome formation, behavior and fate has been largely inferred from observational studies in plants and humans as well as artificially produced de novo dicentrics in yeast and in human cells. We investigate the most recent product of a chromosome fusion event fixed in the human lineage, human chromosome 2, whose stability was acquired by the suppression of one centromere, resulting in a unique difference in chromosome number between humans (46 chromosomes) and our most closely related ape relatives (48 chromosomes). Using molecular cytogenetics, sequencing, and comparative sequence data, we deeply characterize the relicts of the chromosome 2q ancestral centromere and its flanking regions, gaining insight into the ancestral organization that can be easily broadened to all acrocentric chromosome centromeres. Moreover, our analyses offered the opportunity to trace the evolutionary history of rDNA and satellite III sequences among great apes, thus suggesting a new hypothesis for the preferential inactivation of some human centromeres, including IIq. Our results suggest two possible centromere inactivation models to explain the evolutionarily stabilization of human chromosome 2 over the last 5-6 million years. Our results strongly favor centromere excision through a one-step process. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

An insight into the mechanism and evolution of shale reservoir characteristics with over-high maturity

Directory of Open Access Journals (Sweden)

Xinjing Li

2016-10-01

Full Text Available Over-high maturity is one of the most vital characteristics of marine organic-rich shale reservoirs from the Lower Paleozoic in the south part of China. The organic matter (OM in shale gas reservoirs almost went through the entire thermal evolution. During this wide span, a great amount of hydrocarbon was available and numerous pores were observed within the OM including kerogen and solid bitumen/pyrobitumen. These nanopores in solid bitumen/pyrobitumen can be identified using SEM. The imaging can be dissected and understood better based on the sequence of diagenesis and hydrocarbon charge with the shape of OM and pores. In terms of the maturity process showed by the various typical cases, the main effects of the relationship between the reservoir porosity and organic carbon abundance are interpreted as follows: the change and mechanism of reservoirs properties due to thermal evolution are explored, such as gas carbon isotope from partial to complete rollover zone, wettability alteration from water-wet to oil-wet and then water-wet pore surface again, electrical resistivity reversal from the increasing to decreasing stage, and nonlinearity fluctuation of rock elasticity anisotropy. These indicate a possible evolution pathway for shale gas reservoirs from the Lower Paleozoic in the southern China, as well as the general transformation processes between different shale reservoirs in thermal stages.

The Physics of Open Ended Evolution

Science.gov (United States)

Adams, Alyssa M.

What makes living systems different than non-living ones? Unfortunately this question is impossible to answer, at least currently. Instead, we must face computationally tangible questions based on our current understanding of physics, computation, information, and biology. Yet we have few insights into how living systems might quantifiably differ from their non-living counterparts, as in a mathematical foundation to explain away our observations of biological evolution, emergence, innovation, and organization. The development of a theory of living systems, if at all possible, demands a mathematical understanding of how data generated by complex biological systems changes over time. In addition, this theory ought to be broad enough as to not be constrained to an Earth-based biochemistry. In this dissertation, the philosophy of studying living systems from the perspective of traditional physics is first explored as a motivating discussion for subsequent research. Traditionally, we have often thought of the physical world from a bottom-up approach: things happening on a smaller scale aggregate into things happening on a larger scale. In addition, the laws of physics are generally considered static over time. Research suggests that biological evolution may follow dynamic laws that (at least in part) change as a function of the state of the system. Of the three featured research projects, cellular automata (CA) are used as a model to study certain aspects of living systems in two of them. These aspects include self-reference, open-ended evolution, local physical universality, subjectivity, and information processing. Open-ended evolution and local physical universality are attributed to the vast amount of innovation observed throughout biological evolution. Biological systems may distinguish themselves in terms of information processing and storage, not outside the theory of computation. The final research project concretely explores real-world phenomenon by means of

The rule of declining adaptability in microbial evolution experiments

Science.gov (United States)

Couce, Alejandro; Tenaillon, Olivier A.

2015-01-01

One of the most recurrent observations after two decades of microbial evolution experiments regards the dynamics of fitness change. In a given environment, low-fitness genotypes are recurrently observed to adapt faster than their more fit counterparts. Since adaptation is the main macroscopic outcome of Darwinian evolution, studying its patterns of change could potentially provide insight into key issues of evolutionary theory, from fixation dynamics to the genetic architecture of organisms. Here, we re-analyze several published datasets from experimental evolution with microbes and show that, despite large differences in the origin of the data, a pattern of inverse dependence of adaptability with fitness clearly emerges. In quantitative terms, it is remarkable to observe little if any degree of idiosyncrasy across systems as diverse as virus, bacteria and yeast. The universality of this phenomenon suggests that its emergence might be understood from general principles, giving rise to the exciting prospect that evolution might be statistically predictable at the macroscopic level. We discuss these possibilities in the light of the various theories of adaptation that have been proposed and delineate future directions of research. PMID:25815007

Coarse Initial Orbit Determination for a Geostationary Satellite Using Single-Epoch GPS Measurements

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Ghangho Kim

2015-04-01

Full Text Available A practical algorithm is proposed for determining the orbit of a geostationary orbit (GEO satellite using single-epoch measurements from a Global Positioning System (GPS receiver under the sparse visibility of the GPS satellites. The algorithm uses three components of a state vector to determine the satellite’s state, even when it is impossible to apply the classical single-point solutions (SPS. Through consideration of the characteristics of the GEO orbital elements and GPS measurements, the components of the state vector are reduced to three. However, the algorithm remains sufficiently accurate for a GEO satellite. The developed algorithm was tested on simulated measurements from two or three GPS satellites, and the calculated maximum position error was found to be less than approximately 40 km or even several kilometers within the geometric range, even when the classical SPS solution was unattainable. In addition, extended Kalman filter (EKF tests of a GEO satellite with the estimated initial state were performed to validate the algorithm. In the EKF, a reliable dynamic model was adapted to reduce the probability of divergence that can be caused by large errors in the initial state.

Coarse Initial Orbit Determination for a Geostationary Satellite Using Single-Epoch GPS Measurements

Science.gov (United States)

Kim, Ghangho; Kim, Chongwon; Kee, Changdon

2015-01-01

A practical algorithm is proposed for determining the orbit of a geostationary orbit (GEO) satellite using single-epoch measurements from a Global Positioning System (GPS) receiver under the sparse visibility of the GPS satellites. The algorithm uses three components of a state vector to determine the satellite’s state, even when it is impossible to apply the classical single-point solutions (SPS). Through consideration of the characteristics of the GEO orbital elements and GPS measurements, the components of the state vector are reduced to three. However, the algorithm remains sufficiently accurate for a GEO satellite. The developed algorithm was tested on simulated measurements from two or three GPS satellites, and the calculated maximum position error was found to be less than approximately 40 km or even several kilometers within the geometric range, even when the classical SPS solution was unattainable. In addition, extended Kalman filter (EKF) tests of a GEO satellite with the estimated initial state were performed to validate the algorithm. In the EKF, a reliable dynamic model was adapted to reduce the probability of divergence that can be caused by large errors in the initial state. PMID:25835299

Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis

DEFF Research Database (Denmark)

Krøigård, Anne Bruun; Larsen, Martin Jakob; Lænkholm, Anne Vibeke

2015-01-01

Evolution of the breast cancer genome from pre-invasive stages to asynchronous metastasis is complex and mostly unexplored, but highly demanded as it may provide novel markers for and mechanistic insights in cancer progression. The increasing use of personalized therapy of breast cancer necessita......Evolution of the breast cancer genome from pre-invasive stages to asynchronous metastasis is complex and mostly unexplored, but highly demanded as it may provide novel markers for and mechanistic insights in cancer progression. The increasing use of personalized therapy of breast cancer...... progression from one breast cancer patient, including two different regions of Ductal Carcinoma In Situ (DCIS), primary tumor and an asynchronous metastasis. We identify a remarkable landscape of somatic mutations, retained throughout breast cancer progression and with new mutational events emerging at each...

Empowering insight: The role of collaboration in the evolution of intelligence practice

Directory of Open Access Journals (Sweden)

Craig Fleisher

2016-08-01

Conclusion: The evidence we have amassed provides substantial evidence of a notable and beneficial shift from doing intelligence work independently, frequently within silos, towards doing it collaboratively and across multiple types of boundaries. Intelligence practitioners are growing in their capabilities by taking advantage of emerging technologies, adapting practices imported from adjacent fields and benefitting from academic and/or scholarly research that helps push ahead the working boundaries of the field and allows it to make progress. In our view, CMI practice has recently entered a third era of evolution, one in which collaboration will continue to feature prominently, if not centrally.

New Measurement for Correlation of Co-evolution Relationship of Subsequences in Protein.

Science.gov (United States)

Gao, Hongyun; Yu, Xiaoqing; Dou, Yongchao; Wang, Jun

2015-12-01

Many computational tools have been developed to measure the protein residues co-evolution. Most of them only focus on co-evolution for pairwise residues in a protein sequence. However, number of residues participate in co-evolution might be multiple. And some co-evolved residues are clustered in several distinct regions in primary structure. Therefore, the co-evolution among the adjacent residues and the correlation between the distinct regions offer insights into function and evolution of the protein and residues. Subsequence is used to represent the adjacent multiple residues in one distinct region. In the paper, co-evolution relationship in each subsequence is represented by mutual information matrix (MIM). Then, Pearson's correlation coefficient: R value is developed to measure the similarity correlation of two MIMs. MSAs from Catalytic Data Base (Catalytic Site Atlas, CSA) are used for testing. R value characterizes a specific class of residues. In contrast to individual pairwise co-evolved residues, adjacent residues without high individual MI values are found since the co-evolved relationship among them is similar to that among another set of adjacent residues. These subsequences possess some flexibility in the composition of side chains, such as the catalyzed environment.

Analyzing endocrine system conservation and evolution.

Science.gov (United States)

Bonett, Ronald M

2016-08-01

Analyzing variation in rates of evolution can provide important insights into the factors that constrain trait evolution, as well as those that promote diversification. Metazoan endocrine systems exhibit apparent variation in evolutionary rates of their constituent components at multiple levels, yet relatively few studies have quantified these patterns and analyzed them in a phylogenetic context. This may be in part due to historical and current data limitations for many endocrine components and taxonomic groups. However, recent technological advancements such as high-throughput sequencing provide the opportunity to collect large-scale comparative data sets for even non-model species. Such ventures will produce a fertile data landscape for evolutionary analyses of nucleic acid and amino acid based endocrine components. Here I summarize evolutionary rate analyses that can be applied to categorical and continuous endocrine traits, and also those for nucleic acid and protein-based components. I emphasize analyses that could be used to test whether other variables (e.g., ecology, ontogenetic timing of expression, etc.) are related to patterns of rate variation and endocrine component diversification. The application of phylogenetic-based rate analyses to comparative endocrine data will greatly enhance our understanding of the factors that have shaped endocrine system evolution. Copyright © 2016 Elsevier Inc. All rights reserved.

Darwinism and the cultural evolution of sports.

Science.gov (United States)

De Block, Andreas; Dewitte, Siegfried

2009-01-01

This article outlines a Darwinian approach to sports that takes into account its profoundly cultural character and thereby overcomes the traditional nature-culture dichotomies in the sociology of sport. We argue that there are good reasons to view sports as culturally evolved signaling systems that serve a function similar to (biological) courtship rituals in other animals. Our approach combines the insights of evolutionary psychology, which states that biological adaptations determine the boundaries for the types of sport that are possible, and pure cultural theories, which describe the mechanism of cultural evolution without referring to sport's biological bases. Several biological and cultural factors may moderate the direct effect that signaling value has on a sport's viability or popularity. Social learning underlies many aspects of the cultural control of sports, and sports have evolved new cultural functions more-or-less unrelated to mate choice as cultural evolution itself became important in humans.

Insights into the Mechanisms of Chloroplast Division

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Yamato Yoshida

2018-03-01

Full Text Available The endosymbiosis of a free-living cyanobacterium into an ancestral eukaryote led to the evolution of the chloroplast (plastid more than one billion years ago. Given their independent origins, plastid proliferation is restricted to the binary fission of pre-existing plastids within a cell. In the last 25 years, the structure of the supramolecular machinery regulating plastid division has been discovered, and some of its component proteins identified. More recently, isolated plastid-division machineries have been examined to elucidate their structural and mechanistic details. Furthermore, complex studies have revealed how the plastid-division machinery morphologically transforms during plastid division, and which of its component proteins play a critical role in generating the contractile force. Identifying the three-dimensional structures and putative functional domains of the component proteins has given us hints about the mechanisms driving the machinery. Surprisingly, the mechanisms driving plastid division resemble those of mitochondrial division, indicating that these division machineries likely developed from the same evolutionary origin, providing a key insight into how endosymbiotic organelles were established. These findings have opened new avenues of research into organelle proliferation mechanisms and the evolution of organelles.

Methodological proposal for the jotted issue of the first epoch of the Hero magazine.

Directory of Open Access Journals (Sweden)

Maité García Díaz

2013-07-01

Full Text Available During the neocolonial republic emerges in Sancti Spiritus a very significative magazine of artistic, literary and scientific sketch: Hero, founded by Jacinto Gomer Fernández-Morera and Anastacio Fernández-Morera del Castillo, it first appeared on December 20th 1907. This issue constitutes a vivid reflect of the commercial, literary, cultural, scientific and historic panorama and above all, of the life of the middle and high class in Sancti Spiritus at the beginning of the XX century. The need to divulge the advantage the texts of Hero constitute for the high school and university students, also to humanistic profile graduates and others, such as investigators, evidenced the need to carry out an investigation that pursued such purposes. That’s why the methodological proposal for the jotted issue of the first epoch of the Hero magazine (1907-1908 takes place, composed by 38 publications, departing from the fundamental theorizations about the jotted issue of the presentation of the methodological proposal on behalf of updating these publication texts for its potential readers.

Simultaneously constraining the astrophysics of reionisation and the epoch of heating with 21CMMC

Science.gov (United States)

Greig, Bradley; Mesinger, Andrei

2018-05-01

We extend our MCMC sampler of 3D EoR simulations, 21CMMC, to perform parameter estimation directly on light-cones of the cosmic 21cm signal. This brings theoretical analysis one step closer to matching the expected 21-cm signal from next generation interferometers like HERA and the SKA. Using the light-cone version of 21CMMC, we quantify biases in the recovered astrophysical parameters obtained from the 21cm power spectrum when using the co-eval approximation to fit a mock 3D light-cone observation. While ignoring the light-cone effect does not bias the parameters under most assumptions, it can still underestimate their uncertainties. However, significant biases (~few - 10 σ) are possible if all of the following conditions are met: (i) foreground removal is very efficient, allowing large physical scales (k ~ 0.1 Mpc-1) to be used in the analysis; (ii) theoretical modelling is accurate to ~10 per cent in the power spectrum amplitude; and (iii) the 21cm signal evolves rapidly (i.e. the epochs of reionisation and heating overlap significantly

Analytical solutions of accreting black holes immersed in a {Lambda}CDM model

Energy Technology Data Exchange (ETDEWEB)

Lima, J.A.S., E-mail: limajas@astro.iag.usp.b [Universidade de Sao Paulo - Instituto de Astronomia, Geofisica e Ciencias Atmosfericas, Rua do Matao, 1226, 05508-090 Cidade Universitaria, Sao Paulo - SP (Brazil); Guariento, Daniel C., E-mail: carrasco@fma.if.usp.b [Universidade de Sao Paulo - Instituto de Fisica, Rua do Matao, Travessa R, 187, 05508-090 Cidade Universitaria, Sao Paulo - SP (Brazil); Horvath, J.E., E-mail: foton@astro.iag.usp.b [Universidade de Sao Paulo - Instituto de Astronomia, Geofisica e Ciencias Atmosfericas, Rua do Matao, 1226, 05508-090 Cidade Universitaria, Sao Paulo - SP (Brazil)

2010-10-04

The evolution of the mass of a black hole embedded in a universe filled with dark energy and cold dark matter is calculated in a closed form within a test fluid model in a Schwarzschild metric, taking into account the cosmological evolution of both fluids. The result describes exactly how accretion asymptotically switches from the matter-dominated to the {Lambda}-dominated regime. For early epochs, the black hole mass increases due to dark matter accretion, and on later epochs the increase in mass stops as dark energy accretion takes over. Thus, the unphysical behaviour of previous analyses is improved in this simple exact model.

Are species' responses to global change predicted by past niche evolution?

Science.gov (United States)

Lavergne, Sébastien; Evans, Margaret E. K.; Burfield, Ian J.; Jiguet, Frederic; Thuiller, Wilfried

2013-01-01

Predicting how and when adaptive evolution might rescue species from global change, and integrating this process into tools of biodiversity forecasting, has now become an urgent task. Here, we explored whether recent population trends of species can be explained by their past rate of niche evolution, which can be inferred from increasingly available phylogenetic and niche data. We examined the assemblage of 409 European bird species for which estimates of demographic trends between 1970 and 2000 are available, along with a species-level phylogeny and data on climatic, habitat and trophic niches. We found that species' proneness to demographic decline is associated with slow evolution of the habitat niche in the past, in addition to certain current-day life-history and ecological traits. A similar result was found at a higher taxonomic level, where families prone to decline have had a history of slower evolution of climatic and habitat niches. Our results support the view that niche conservatism can prevent some species from coping with environmental change. Thus, linking patterns of past niche evolution and contemporary species dynamics for large species samples may provide insights into how niche evolution may rescue certain lineages in the face of global change. PMID:23209172

Can the experimental evolution programme help us elucidate the genetic basis of adaptation in nature?

DEFF Research Database (Denmark)

Bailey, Susan; Bataillon, Thomas

2015-01-01

and continue to play an important role in shaping adaptive evolution in the natural world. Further to this, experimental evolution studies allow for tests of theories that may be difficult or impossible to test in natural populations for logistical and methodological reasons and can even generate new insights......, suggesting further refinement of existing theories. However, as experimental evolution studies often take place in a very particular set of controlled conditions – that is simple environments, a small range of usually asexual species, relatively short timescales – the question remains as to how applicable...... natural population studies. We finish by making suggestions for future work in particular a need for natural population genomic time series data, as well as the necessity for studies that combine both experimental evolution and natural population approaches....

Constraining the evolution of the Hubble Parameter using cosmic chronometer

Science.gov (United States)

Scarlata, Claudia; Dickinson, Hugh

2018-01-01

The Lambda-CDM model of Big Bang cosmology relies heavily on the assumption that two components - dark energy and dark matter - encompass 95% of the energy density of the Universe. Despite the dominant influence of these components, their nature is still entirely unknown.We present the initial results from a project that aims to provide new insights regarding the Dark Energy component. We do this by deriving independent constraints on the time-evolution of the Hubble parameter (H_0) using the “cosmic chronometer” method.By analyzing the HST NIR spectra from a large archival sample of passively evolving galaxies in distinct redshift bins between 1.3 and 2 we measure the typical stellar population ages (A) for the galaxies in each bin. The differential evolution of stellar population age with redshift (dA/dz) can be used to infer the corresponding evolution of H_0 which will provide important constraints on the nature of Dark Energy and its equation of state.

Relatedness, conflict, and the evolution of eusociality.

Directory of Open Access Journals (Sweden)

Xiaoyun Liao

2015-03-01

Full Text Available The evolution of sterile worker castes in eusocial insects was a major problem in evolutionary theory until Hamilton developed a method called inclusive fitness. He used it to show that sterile castes could evolve via kin selection, in which a gene for altruistic sterility is favored when the altruism sufficiently benefits relatives carrying the gene. Inclusive fitness theory is well supported empirically and has been applied to many other areas, but a recent paper argued that the general method of inclusive fitness was wrong and advocated an alternative population genetic method. The claim of these authors was bolstered by a new model of the evolution of eusociality with novel conclusions that appeared to overturn some major results from inclusive fitness. Here we report an expanded examination of this kind of model for the evolution of eusociality and show that all three of its apparently novel conclusions are essentially false. Contrary to their claims, genetic relatedness is important and causal, workers are agents that can evolve to be in conflict with the queen, and eusociality is not so difficult to evolve. The misleading conclusions all resulted not from incorrect math but from overgeneralizing from narrow assumptions or parameter values. For example, all of their models implicitly assumed high relatedness, but modifying the model to allow lower relatedness shows that relatedness is essential and causal in the evolution of eusociality. Their modeling strategy, properly applied, actually confirms major insights of inclusive fitness studies of kin selection. This broad agreement of different models shows that social evolution theory, rather than being in turmoil, is supported by multiple theoretical approaches. It also suggests that extensive prior work using inclusive fitness, from microbial interactions to human evolution, should be considered robust unless shown otherwise.

New Finds of Painted Ceramics of the Epoch of the Abkhazian Kingdom

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Armarchuk Ekaterina A.

2012-03-01

Full Text Available The painted polished red-clay ceramic items of the 8th-10th centuries, found on the Anakopia and other sites of Northern Abkhazia and the adjoining district of the city of Sochi are considered in the article. These are small and medium sized single-handled narrow-necked jugs. The painting is made in dark brown paint. The ornament consists mainly of straight and wavy lines; hatching in the form of oblique grids, braids and patterns of specks occur. Taking into account the new finds made during the 2007-2008 excavations of the necropolis on the Sakharnaya Golovka Mountain and of the church near Veseloye village, the analysis of painted polished ware of the Abkhazian Kingdom epoch makes it possible to determine its territorial and chronological distribution limits. The area of this pottery covers the Black Sea coast from the mouth of the Mzymta river to New Athos. Based on the results of the 1950-1980s excavations, it has been dated to the 8th-10th centuries; however, the new materials allow restricting the interval to the 9th-10th centuries. The differences in the vessels manufacturing technology indicate the presence of at least two production centers. The small painted burnished jars discovered in Christian graves suggest that they had been used to store incense or chrism.

An Adaptive Laboratory Evolution Method to Accelerate Autotrophic Metabolism

DEFF Research Database (Denmark)

Zhang, Tian; Tremblay, Pier-Luc

2018-01-01

Adaptive laboratory evolution (ALE) is an approach enabling the development of novel characteristics in microbial strains via the application of a constant selection pressure. This method is also an efficient tool to acquire insights on molecular mechanisms responsible for specific phenotypes. ALE...... autotrophically and reducing CO2 into acetate more efficiently. Strains developed via this ALE method were also used to gain knowledge on the autotrophic metabolism of S. ovata as well as other acetogenic bacteria....

Uncertainty about social interactions leads to the evolution of social heuristics.

Science.gov (United States)

van den Berg, Pieter; Wenseleers, Tom

2018-05-31

Individuals face many types of social interactions throughout their lives, but they often cannot perfectly assess what the consequences of their actions will be. Although it is known that unpredictable environments can profoundly affect the evolutionary process, it remains unclear how uncertainty about the nature of social interactions shapes the evolution of social behaviour. Here, we present an evolutionary simulation model, showing that even intermediate uncertainty leads to the evolution of simple cooperation strategies that disregard information about the social interaction ('social heuristics'). Moreover, our results show that the evolution of social heuristics can greatly affect cooperation levels, nearly doubling cooperation rates in our simulations. These results provide new insight into why social behaviour, including cooperation in humans, is often observed to be seemingly suboptimal. More generally, our results show that social behaviour that seems maladaptive when considered in isolation may actually be well-adapted to a heterogeneous and uncertain world.

Host imprints on bacterial genomes--rapid, divergent evolution in individual patients.

Directory of Open Access Journals (Sweden)

Jaroslaw Zdziarski

Full Text Available Bacteria lose or gain genetic material and through selection, new variants become fixed in the population. Here we provide the first, genome-wide example of a single bacterial strain's evolution in different deliberately colonized patients and the surprising insight that hosts appear to personalize their microflora. By first obtaining the complete genome sequence of the prototype asymptomatic bacteriuria strain E. coli 83972 and then resequencing its descendants after therapeutic bladder colonization of different patients, we identified 34 mutations, which affected metabolic and virulence-related genes. Further transcriptome and proteome analysis proved that these genome changes altered bacterial gene expression resulting in unique adaptation patterns in each patient. Our results provide evidence that, in addition to stochastic events, adaptive bacterial evolution is driven by individual host environments. Ongoing loss of gene function supports the hypothesis that evolution towards commensalism rather than virulence is favored during asymptomatic bladder colonization.

Evolution of Ion Implantation Technology and its Contribution to Semiconductor Industry

International Nuclear Information System (INIS)

Tsukamoto, Katsuhiro; Kuroi, Takashi; Kawasaki, Yoji

2011-01-01

Industrial aspects of the evolution of ion implantation technology will be reviewed, and their impact on the semiconductor industry will be discussed. The main topics will be the technology's application to the most advanced, ultra scaled CMOS, and to power devices, as well as productivity improvements in implantation technology. Technological insights into future developments in ion-related technologies for emerging industries will also be presented.

TIME EVOLUTION OF WOUTHUYSEN-FIELD COUPLING

International Nuclear Information System (INIS)

Roy, Ishani; Shu Chiwang; Xu Wen; Fang Lizhi; Qiu Jingmei

2009-01-01

We study the Wouthuysen-Field (W-F) coupling at early universe with numerical solutions of the integrodifferential equation describing the kinetics of photons undergoing resonant scattering. The numerical solver is developed based on the weighted essentially nonoscillatory (WENO) scheme for the Boltzmann-like integrodifferential equation. This method has perfectly passed the tests of the analytic solution and conservation property of the resonant scattering equation. We focus on the time evolution of the Wouthuysen-Field (W-F) coupling in relation to the 21 cm emission and absorption at the epoch of reionization. We especially pay attention to the formation of the local Boltzmann distribution, e -(ν-ν 0 )/kT , of photon frequency spectrum around resonant frequency ν 0 within width ν l , i.e., |ν - ν 0 | ≤ ν l . We show that a local Boltzmann distribution will be formed if photons with frequency ∼ν 0 have undergone a 10,000 or more times of scattering, which corresponds to the order of 10 3 yr for neutral hydrogen density of the concordance ΛCDM model. The time evolution of the shape and width of the local Boltzmann distribution actually do not depend on the details of atomic recoil, photon sources, or initial conditions very much. However, the intensity of photon flux at the local Boltzmann distribution is substantially time dependent. The timescale of approaching the saturated intensity can be as long as 10 5 -10 6 yr for typical parameters of the ΛCDM model. The intensity of the local Boltzmann distribution at time less than 10 5 yr is significantly lower than that of the saturation state. Therefore, it may not be always reasonable to assume that the deviation of the spin temperature of 21 cm energy states from cosmic background temperature is mainly due to the W-F coupling if first stars or their emission/absorption regions evolved with a timescale equal to or less than Myr.

The Cotesia sesamiae story: insight into host-range evolution in a Hymenoptera parasitoid and implication for its use in biological control programs.

Science.gov (United States)

Kaiser, L; Dupas, S; Branca, A; Herniou, E A; Clarke, C W; Capdevielle Dulac, C; Obonyo, J; Benoist, R; Gauthier, J; Calatayud, P A; Silvain, J F; Le Ru, B P

2017-12-01

This review covers nearly 20 years of studies on the ecology, physiology and genetics of the Hymenoptera Cotesia sesamiae, an African parasitoid of Lepidoptera that reduces populations of common maize borers in East and South Africa. The first part of the review presents studies based on sampling of C. sesamiae from maize crops in Kenya. From this agrosystem including one host plant and three main host borer species, studies revealed two genetically differentiated populations of C. sesamiae species adapted to their local host community, and showed that their differentiation involved the joint evolution of virulence genes and sensory mechanisms of host acceptance, reinforced by reproductive incompatibility due to Wolbachia infection status and natural inbreeding. In the second part, we consider the larger ecosystem of wild Poales plant species hosting many Lepidoptera stem borer species that are potential hosts for C. sesamiae. The hypothesis of other host-adapted C. sesamiae populations was investigated based on a large sampling of stem borer larvae on various Poales across sub-Saharan Africa. The sampling provided information on the respective contribution of local hosts, biogeography and Wolbachia in the genetic structure of C. sesamiae populations. Molecular evolution analyses highlighted that several bracovirus genes were under positive selection, some of them being under different selection pressure in C. sesamiae populations adapted to different hosts. This suggests that C. sesamiae host races result from co-evolution acting at the local scale on different bracovirus genes. The third part considers the mechanisms driving specialization. C. sesamiae host races are more or less host-specialized. This character is crucial for efficient and environmentally-safe use of natural enemies for biological control of pests. One method to get an insight in the evolutionary stability of host-parasite associations is to characterize the phylogenetic relationships between

Improvisation in evolution of genes and genomes: whose structure is it anyway?

Science.gov (United States)

Shakhnovich, Boris E; Shakhnovich, Eugene I

2008-06-01

Significant progress has been made in recent years in a variety of seemingly unrelated fields such as sequencing, protein structure prediction, and high-throughput transcriptomics and metabolomics. At the same time, new microscopic models have been developed that made it possible to analyze the evolution of genes and genomes from first principles. The results from these efforts enable, for the first time, a comprehensive insight into the evolution of complex systems and organisms on all scales--from sequences to organisms and populations. Every newly sequenced genome uncovers new genes, families, and folds. Where do these new genes come from? How do gene duplication and subsequent divergence of sequence and structure affect the fitness of the organism? What role does regulation play in the evolution of proteins and folds? Emerging synergism between data and modeling provides first robust answers to these questions.

MULTI-EPOCH VERY LONG BASELINE ARRAY OBSERVATIONS OF THE COMPACT WIND-COLLISION REGION IN THE QUADRUPLE SYSTEM Cyg OB2 no. 5

Energy Technology Data Exchange (ETDEWEB)

Dzib, Sergio A.; Rodriguez, Luis F.; Loinard, Laurent; Ortiz-Leon, Gisela N.; Araudo, Anabella T. [Centro de Radiostronomia y Astrofisica, Universidad Nacional Autonoma de Mexico, Morelia 58089 (Mexico); Mioduszewski, Amy J., E-mail: s.dzib@crya.unam.mx [National Radio Astronomy Observatory, 1003 Lopezville Road, Socorro, NM 87801 (United States)

2013-02-15

We present multi-epoch Very Long Base Array observations of the compact wind-collision region in the Cyg OB2 no. 5 system. These observations confirm the arc-shaped morphology of the emission reported earlier. The total flux as a function of time is roughly constant when the source is 'on', but falls below the detection limit as the wind-collision region approaches periastron in its orbit around the contact binary at the center of the system. In addition, at one of the 'on' epochs, the flux drops to about a fifth of its average value. We suggest that this apparent variation could result from the inhomogeneity of the wind that hides part of the flux rather than from an intrinsic variation. We measured a trigonometrical parallax, for the most compact radio emission of 0.61 {+-} 0.22 mas, corresponding to a distance of 1.65 {sup +0.96} {sub -0.44} kpc, in agreement with recent trigonometrical parallaxes measured for objects in the Cygnus X complex. Using constraints on the total mass of the system and orbital parameters previously reported in the literature, we obtain two independent indirect measurements of the distance to the Cyg OB2 no. 5 system, both consistent with 1.3-1.4 kpc. Finally, we suggest that the companion star responsible for the wind interaction, yet undetected, is of spectral type between B0.5 and O8.

MULTI-EPOCH VERY LONG BASELINE ARRAY OBSERVATIONS OF THE COMPACT WIND-COLLISION REGION IN THE QUADRUPLE SYSTEM Cyg OB2 no. 5

International Nuclear Information System (INIS)

Dzib, Sergio A.; Rodríguez, Luis F.; Loinard, Laurent; Ortiz-León, Gisela N.; Araudo, Anabella T.; Mioduszewski, Amy J.

2013-01-01

We present multi-epoch Very Long Base Array observations of the compact wind-collision region in the Cyg OB2 no. 5 system. These observations confirm the arc-shaped morphology of the emission reported earlier. The total flux as a function of time is roughly constant when the source is 'on', but falls below the detection limit as the wind-collision region approaches periastron in its orbit around the contact binary at the center of the system. In addition, at one of the 'on' epochs, the flux drops to about a fifth of its average value. We suggest that this apparent variation could result from the inhomogeneity of the wind that hides part of the flux rather than from an intrinsic variation. We measured a trigonometrical parallax, for the most compact radio emission of 0.61 ± 0.22 mas, corresponding to a distance of 1.65 +0.96 –0.44 kpc, in agreement with recent trigonometrical parallaxes measured for objects in the Cygnus X complex. Using constraints on the total mass of the system and orbital parameters previously reported in the literature, we obtain two independent indirect measurements of the distance to the Cyg OB2 no. 5 system, both consistent with 1.3-1.4 kpc. Finally, we suggest that the companion star responsible for the wind interaction, yet undetected, is of spectral type between B0.5 and O8.

Insight Into the Origin and Evolution of the Vibrio parahaemolyticus Pandemic Strain

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Romilio T. Espejo

2017-07-01

Full Text Available A strain of Vibrio parahaemolyticus that emerged in 1995 caused the first known pandemic involving this species. This strain comprises clonal autochthonous ocean-dwelling bacteria whose evolution has occurred in the ocean environment. The low sequence diversity in this population enabled the discovery of information on its origin and evolution that has been hidden in bacterial clones that have evolved over a long period. Multilocus sequencing and microarray analysis, together with phylogenetic analysis, of pandemic and pre-pandemic isolates has suggested that the founder clone was an O3:K6 non-pathogenic strain that initially acquired a toxRS/new region and subsequently acquired at least seven novel genomic islands. Sequencing and comparison of whole genomes later confirmed these early observations, and it confirmed that most of the genetic changes occurred via gene conversion involving horizontally transmitted DNA. The highly clonal population rapidly diversified, especially in terms of antigenicity, and 27 serotypes have already been reported. Comparisons of the core genomes derived from the founder clone indicate that there are only a few hundred single-nucleotide variations between isolates. However, when the whole genome is considered (the core plus non-core genome and from any clonal frame, the amount of DNA with a different clonal frame can reach up to 4.2% and the number of single-nucleotide variations can reach several hundred thousand. Altogether, these and previous observations based on multilocus sequence typing, microarray analysis, and whole-genome sequencing indicate the large contribution made by DNA with different clonal genealogy to genome diversification. The evidence also indicates that horizontal gene transfer (HGT caused the emergence of new pathogens. Furthermore, the extent of HGT seems to depend on the vicissitudes of the life of each bacterium, as exemplified by differences in thousands of base pairs acquired by HGT

Senescence in the wild: Insights from a long-term study on Seychelles warblers.

Science.gov (United States)

Hammers, Martijn; Kingma, Sjouke A; Bebbington, Kat; van de Crommenacker, Janske; Spurgin, Lewis G; Richardson, David S; Burke, Terry; Dugdale, Hannah L; Komdeur, Jan

2015-11-01

Senescence--the progressive age-dependent decline in performance--occurs in most organisms. There is considerable variation in the onset and rate of senescence between and within species. Yet the causes of this variation are still poorly understood, despite being central to understanding the evolution of senescence. Long-term longitudinal studies on wild animals are extremely well-suited to studying the impact of environmental and individual characteristics (and the interaction between the two) on senescence, and can help us to understand the mechanisms that shape the evolution of senescence. In this review, we summarize and discuss the insights gained from our comprehensive long-term individual-based study of the Seychelles warbler (Acrocephalus sechellensis). This species provides an excellent model system in which to investigate the evolution of senescence in the wild. We found that Seychelles warblers show senescent declines in survival and reproduction, and discuss how individual characteristics (body condition, body size) and environmental effects (low- versus high-quality environments) may affect the onset and rate of senescence. Further, we highlight the evidence for trade-offs between early-life investment and senescence. We describe how key cellular and physiological processes (oxidative stress and telomere shortening) underpinning senescence are affected by individual and environmental characteristics in the Seychelles warbler (e.g. food availability, reproductive investment, disease) and we discuss how such physiological variation may mediate the relationship between environmental characteristics and senescence. Based on our work using Seychelles warblers as a model system, we show how insights from long-term studies of wild animals may help unravel the causes of the remarkable variation in senescence observed in natural systems, and highlight areas for promising future research.

Hydrogen Epoch of Reinozation Array (HERA) Calibrated FFT Correlator Simulation

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Salazar, Jeffrey David; Parsons, Aaron

2018-01-01

The Hydrogen Epoch of Reionization Array (HERA) project is an astronomical radio interferometer array with a redundant baseline configuration. Interferometer arrays are being used widely in radio astronomy because they have a variety of advantages over single antenna systems. For example, they produce images (visibilities) closely matching that of a large antenna (such as the Arecibo observatory), while both the hardware and maintenance costs are significantly lower. However, this method has some complications; one being the computational cost of correlating data from all of the antennas. A correlator is an electronic device that cross-correlates the data between the individual antennas; these are what radio astronomers call visibilities. HERA, being in its early stages, utilizes a traditional correlator system. The correlator cost scales as N2, where N is the number of antennas in the array. The purpose of a redundant baseline configuration array setup is for the use of a more efficient Fast Fourier Transform (FFT) correlator. FFT correlators scale as Nlog2N. The data acquired from this sort of setup, however, inherits geometric delay and uncalibrated antenna gains. This particular project simulates the process of calibrating signals from astronomical sources. Each signal “received” by an antenna in the simulation is given random antenna gain and geometric delay. The “linsolve” Python module was used to solve for the unknown variables in the simulation (complex gains and delays), which then gave a value for the true visibilities. This first version of the simulation only mimics a one dimensional redundant telescope array detecting a small amount of sources located in the volume above the antenna plane. Future versions, using GPUs, will handle a two dimensional redundant array of telescopes detecting a large amount of sources in the volume above the array.

The Taxonomy of Blue Amorphous Galaxies. II. Structure and Evolution

Science.gov (United States)

Marlowe, Amanda T.; Meurer, Gerhardt R.; Heckman, Timothy M.

1999-09-01

Dwarf galaxies play an important role in our understanding of galaxy formation and evolution, and starbursts are believed to affect the structure and evolution of dwarf galaxies strongly. We have therefore embarked on a systematic study of 12 of the nearest dwarf galaxies thought to be undergoing bursts of star formation. These were selected primarily by their morphological type (blue ``amorphous'' galaxies). We show that these blue amorphous galaxies are not physically distinguishable from dwarfs selected as starbursting by other methods, such as blue compact dwarfs (BCDs) and H II galaxies. All these classes exhibit surface brightness profiles that are exponential in the outer regions (r>~1.5re) but often have a predominantly central blue excess, suggesting a young burst in an older, redder galaxy. Typically, the starbursting ``cores'' are young (~107-108 yr) events compared to the older (~109-1010 yr) underlying galaxy (the ``envelope''). The ratio of the core to envelope in blue light ranges from essentially zero to about 2. These starbursts are therefore modest events involving only a few percent of the stellar mass. The envelopes have surface brightnesses that are much higher than typical dwarf irregular (dI) galaxies, so it is unlikely that there is a straightforward evolutionary relation between typical dIs and dwarf starburst galaxies. Instead we suggest that amorphous galaxies may repeatedly cycle through starburst and quiescent phases, corresponding to the galaxies with strong and weak/absent cores, respectively. Once amorphous galaxies use up the available gas (either through star formation or galactic winds) so that star formation is shut off, the faded remnants would strongly resemble dwarf elliptical galaxies. However, in the current cosmological epoch, this is evidently a slow process that is the aftermath of a series of many weak, recurring bursts. Present-day dE's must have experienced more rapid and intense evolution than this in the distant past.

Life-history evolution and mitogenomic phylogeny of caecilian amphibians.

Science.gov (United States)

San Mauro, Diego; Gower, David J; Müller, Hendrik; Loader, Simon P; Zardoya, Rafael; Nussbaum, Ronald A; Wilkinson, Mark

2014-04-01

We analyze mitochondrial genomes to reconstruct a robust phylogenetic framework for caecilian amphibians and use this to investigate life-history evolution within the group. Our study comprises 45 caecilian mitochondrial genomes (19 of them newly reported), representing all families and 27 of 32 currently recognized genera, including some for which molecular data had never been reported. Support for all relationships in the inferred phylogenetic tree is high to maximal, and topology tests reject all investigated alternatives, indicating an exceptionally robust molecular phylogenetic framework of caecilian evolution consistent with current morphology-based supraspecific classification. We used the mitogenomic phylogenetic framework to infer ancestral character states and to assess correlation among three life-history traits (free-living larvae, viviparity, specialized pre-adult or vernal teeth), each of which occurs only in some caecilian species. Our results provide evidence that an ancestor of the Seychelles caecilians abandoned direct development and re-evolved a free-living larval stage. This study yields insights into the concurrent evolution of direct development and of vernal teeth in an ancestor of Teresomata that likely gave rise to skin-feeding (maternal dermatophagy) behavior and subsequently enabled evolution of viviparity, with skin feeding possibly a homologous precursor of oviduct feeding in viviparous caecilians. Copyright © 2014 Elsevier Inc. All rights reserved.

MCPH1: a window into brain development and evolution

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Jeannette eNardelli

2015-03-01

Full Text Available The development of the mammalian cerebral cortex involves a series of mechanisms: from patterning, progenitor cell proliferation and differentiation, to neuronal migration. Many factors influence the development of the cerebral cortex to its normal size and neuronal composition. Of these, the mechanisms that influence the proliferation and differentiation of neural progenitor cells are of particular interest, as they may have the greatest consequence on brain size, not only during development but also in evolution. In this context, causative genes of human autosomal recessive primary microcephaly, such as ASPM and MCPH1, are attractive candidates, as many of them show positive selection during primate evolution. MCPH1 causes microcephaly in mice and humans and is involved in a diverse array of molecular functions beyond brain development, including DNA repair and chromosome condensation. Positive selection of MCPH1 in the primate lineage has led to much insight and discussion of its role in brain size evolution. In this review, we will present an overview of MCPH1 from these multiple angles, and whilst its specific role in brain size regulation during development and evolution remain elusive, the pieces of the puzzle will be discussed with the aim of putting together the full picture of this fascinating gene.

Cooperative behavior evolution of small groups on interconnected networks

International Nuclear Information System (INIS)

Huang, Keke; Cheng, Yuan; Zheng, Xiaoping; Yang, Yeqing

2015-01-01

Highlights: • Small groups are modeled on interconnected networks. • Players face different dilemmas inside and outside small groups. • Impact of the ratio and strength of link on the behavioral evolution are studied. - Abstract: Understanding the behavioral evolution in evacuation is significant for guiding and controlling the evacuation process. Based on the fact that the population consists of many small groups, here we model the small groups which are separated in space but linked by other methods, such as kinship, on interconnected networks. Namely, the players in the same layer belong to an identical small group, while the players located in different layers belong to different small groups. And the players of different layers establish interaction by edge crossed layers. In addition, players face different dilemmas inside and outside small groups, in detail, the players in the same layer play prisoner’s dilemma, but players in different layers play harmony game. By means of numerous simulations, we study the impact of the ratio and strength of link on the behavioral evolution. Because the framework of this work takes the space distribution into account, which is close to the realistic life, we hope that it can provide a new insight to reveal the law of behavioral evolution of evacuation population.

Hormonally active phytochemicals and vertebrate evolution.

Science.gov (United States)

Lambert, Max R; Edwards, Thea M

2017-06-01

Living plants produce a diversity of chemicals that share structural and functional properties with vertebrate hormones. Wildlife species interact with these chemicals either through consumption of plant materials or aquatic exposure. Accumulating evidence shows that exposure to these hormonally active phytochemicals (HAPs) often has consequences for behavior, physiology, and fecundity. These fitness effects suggest there is potential for an evolutionary response by vertebrates to HAPs. Here, we explore the toxicological HAP-vertebrate relationship in an evolutionary framework and discuss the potential for vertebrates to adapt to or even co-opt the effects of plant-derived chemicals that influence fitness. We lay out several hypotheses about HAPs and provide a path forward to test whether plant-derived chemicals influence vertebrate reproduction and evolution. Studies of phytochemicals with direct impacts on vertebrate reproduction provide an obvious and compelling system for studying evolutionary toxicology. Furthermore, an understanding of whether animal populations evolve in response to HAPs could provide insightful context for the study of rapid evolution and how animals cope with chemical agents in the environment.

Intelligent system to study demographic evolution

Science.gov (United States)

Rodrigues, M. de Fatima; Ramos, Carlos; Henriques, Pedro R.

1999-02-01

With three centuries of existence, the study of population's behavior implies the manipulation of large amounts of incomplete and imprecise data with high dimensionality. By virtue of its multidisciplinary character, the work in demography involves at least historicists, statisticians and computer scientists/programmers. Moreover, successful demographic analysis requires qualified experts, who have succeeded in analysing data through many views and relate different sources of information, including their personal knowledge of the epoch or regions under study. In this paper, we present an intelligent system to study demographic evolution (ISSDE). This system has a module based on on-line analytical processing (OLAP), which permits conducting multiple analysis, combining many data dimensions. It has a deductive database system, which allows the execution of elaborated queries through the database. It has another module for date treatment (generalization and/or reduction); and, at last, a data mining module to discover nontrivial relations hidden within data. We discover the data treatment procedure with two phases: data generalization and data reduction. In data generalization, utilizing knowledge about concept hierarchies and relevance of data, aggregation of attribute values is performed. In the data reduction phase, rough set theory is applied to compute the minimal attribute set. We highlight the advantages of combining attribute value generalization with rough set theory, to find a subset of attributes that lets the mining process discover more useful patterns, by providing results from the application of the C5.0 algorithm in a demographic relational database.

On the Magnetic Evolution in Friedmann Universes and the Question of Cosmic Magnetogenesis

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Christos G. Tsagas

2016-11-01

Full Text Available We analyse the evolution of primordial magnetic fields in spatially flat Friedmann universes and reconsider the belief that, after inflation, these fields decay adiabatically on all scales. Without abandoning classical electromagnetism or standard cosmology, we demonstrate that this is not necessarily the case for superhorizon-sized magnetic fields. The underlying reason for this is causality, which confines the post-inflationary process of electric-current formation, electric-field elimination and magnetic-flux freezing within the horizon. As a result, the adiabatic magnetic decay is not a priori guaranteed on super-Hubble scales. Instead, after inflation, large-scale magnetic fields obey a power-law solution, where one of the modes drops at a rate slower than the adiabatic. Whether this slowly decaying mode can dominate and dictate the post-inflationary magnetic evolution depends on the initial conditions. These are determined by the evolution of the field during inflation and by the nature of the transition from the de Sitter phase to the reheating era and then to the subsequent epochs of radiation and dust. We discuss two alternative and complementary scenarios to illustrate the role and the implications of the initial conditions for cosmic magnetogenesis. Our main claim is that magnetic fields can be superadiabatically amplified after inflation, as long as they remain outside the horizon. This means that inflation-produced fields can reach astrophysically relevant residual strengths without breaking away from standard physics. Moreover, using the same causality arguments, one can constrain (or in some cases assist the non-conventional scenarios of primordial magnetogenesis that amplify their fields during inflation. Finally, we show that our results extend naturally to the marginally open and the marginally closed Friedmann universes.

Collagen cross-linking: insights on the evolution of metazoan extracellular matrix.

Science.gov (United States)

Rodriguez-Pascual, Fernando; Slatter, David Anthony

2016-11-23

Collagens constitute a large family of extracellular matrix (ECM) proteins that play a fundamental role in supporting the structure of various tissues in multicellular animals. The mechanical strength of fibrillar collagens is highly dependent on the formation of covalent cross-links between individual fibrils, a process initiated by the enzymatic action of members of the lysyl oxidase (LOX) family. Fibrillar collagens are present in a wide variety of animals, therefore often being associated with metazoan evolution, where the emergence of an ancestral collagen chain has been proposed to lead to the formation of different clades. While LOX-generated collagen cross-linking metabolites have been detected in different metazoan families, there is limited information about when and how collagen acquired this particular modification. By analyzing telopeptide and helical sequences, we identified highly conserved, potential cross-linking sites throughout the metazoan tree of life. Based on this analysis, we propose that they have importantly contributed to the formation and further expansion of fibrillar collagens.

The impact of rapid evolution on population dynamics in the wild: experimental test of eco-evolutionary dynamics.

Science.gov (United States)

Turcotte, Martin M; Reznick, David N; Hare, J Daniel

2011-11-01

Rapid evolution challenges the assumption that evolution is too slow to impact short-term ecological dynamics. This insight motivates the study of 'Eco-Evolutionary Dynamics' or how evolution and ecological processes reciprocally interact on short time scales. We tested how rapid evolution impacts concurrent population dynamics using an aphid (Myzus persicae) and an undomesticated host (Hirschfeldia incana) in replicated wild populations. We manipulated evolvability by creating non-evolving (single clone) and potentially evolving (two-clone) aphid populations that contained genetic variation in intrinsic growth rate. We observed significant evolution in two-clone populations whether or not they were exposed to predators and competitors. Evolving populations grew up to 42% faster and attained up to 67% higher density, compared with non-evolving control populations but only in treatments exposed to competitors and predators. Increased density also correlates with relative fitness of competing clones suggesting a full eco-evolutionary dynamic cycle defined as reciprocal interactions between evolution and density. © 2011 Blackwell Publishing Ltd/CNRS.

Evolution of students’ friendship networks: Examining the influence of group size

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Valentina Sokolovska

2017-01-01

Full Text Available  The main aim of this study was to examine the effect of the network size on formation and evolution of students’ friendship relations. Data was collected from two groups of sociology freshmen: a group from the University of Belgrade, which represents a larger group, and a group from the University of Novi Sad, which represents a smaller group. The data was collected in three periods of one academic year. We analyzed the structural features of students’ networks and constructed a stochastic model of network evolution in order to explore how friendships form and change during one year. The results showed that structural features of the larger and the smaller group differ in each stage of friendship formation. At the beginning of group forming, small world structure was noticeable in the larger group, although full small world structure was not confirmed in both groups. Furthermore, transitivity of triads had effect on the evolution of the larger network, while balance or structural equivalence had effect on the evolution of the smaller network. Results of the structural analysis are in line with findings of the network evolution model and together they provide an insight into how friendship evolves in groups of different sizes.

PROBING THE EPOCH OF REIONIZATION WITH THE Lyα FOREST AT z ∼ 4-5

International Nuclear Information System (INIS)

Cen Renyue; McDonald, Patrick; Trac, Hy; Loeb, Abraham

2009-01-01

The inhomogeneous cosmological reionization process leaves tangible imprints in the intergalactic medium (IGM) down to z ∼ 4-5. The Lyα forest flux power spectrum provides a potentially powerful probe of the epoch of reionization. With the existing Sloan Digital Sky Survey I/II quasar sample, we show that two cosmological reionization scenarios, one completing reionization at z = 6 and the other at z = 9, can be distinguished at ∼7σ level by utilizing Lyα forest absorption spectra at z = 3.9-4.1 in the absence of other physical processes that may also affect the Lyα flux power spectrum. The difference may not be distinguishable at such high significance after marginalization over other effects, but, in any case, one will need to consider this effect in order to correctly interpret the power spectrum in this redshift range. The redshift range z = 4-5 may provide the best window because there are still enough transmitted flux and quasars to measure precise statistics of the flux fluctuations, and the IGM still retains a significant amount of memory of reionization.

Farming System Evolution and Adaptive Capacity: Insights for Adaptation Support

Directory of Open Access Journals (Sweden)

Jami L. Dixon

2014-02-01

Full Text Available Studies of climate impacts on agriculture and adaptation often provide current or future assessments, ignoring the historical contexts farming systems are situated within. We investigate how historical trends have influenced farming system adaptive capacity in Uganda using data from household surveys, semi-structured interviews, focus-group discussions and observations. By comparing two farming systems, we note three major findings: (1 similar trends in farming system evolution have had differential impacts on the diversity of farming systems; (2 trends have contributed to the erosion of informal social and cultural institutions and an increasing dependence on formal institutions; and (3 trade-offs between components of adaptive capacity are made at the farm-scale, thus influencing farming system adaptive capacity. To identify the actual impacts of future climate change and variability, it is important to recognize the dynamic nature of adaptation. In practice, areas identified for further adaptation support include: shift away from one-size-fits-all approach the identification and integration of appropriate modern farming method; a greater focus on building inclusive formal and informal institutions; and a more nuanced understanding regarding the roles and decision-making processes of influential, but external, actors. More research is needed to understand farm-scale trade-offs and the resulting impacts across spatial and temporal scales.

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Science.gov (United States)

Liao, Hua-Xin; Lynch, Rebecca; Zhou, Tongqing; Gao, Feng; Alam, S. Munir; Boyd, Scott D.; Fire, Andrew Z.; Roskin, Krishna M.; Schramm, Chaim A.; Zhang, Zhenhai; Zhu, Jiang; Shapiro, Lawrence; Mullikin, James C.; Gnanakaran, S.; Hraber, Peter; Wiehe, Kevin; Kelsoe, Garnett; Yang, Guang; Xia, Shi-Mao; Montefiori, David C.; Parks, Robert; Lloyd, Krissey E.; Scearce, Richard M.; Soderberg, Kelly A.; Cohen, Myron; Kaminga, Gift; Louder, Mark K.; Tran, Lillan M.; Chen, Yue; Cai, Fangping; Chen, Sheri; Moquin, Stephanie; Du, Xiulian; Joyce, Gordon M.; Srivatsan, Sanjay; Zhang, Baoshan; Zheng, Anqi; Shaw, George M.; Hahn, Beatrice H.; Kepler, Thomas B.; Korber, Bette T.M.; Kwong, Peter D.; Mascola, John R.; Haynes, Barton F.

2013-01-01

Current HIV-1 vaccines elicit strain-specific neutralizing antibodies. However, cross-reactive neutralizing antibodies arise in ~20% of HIV-1-infected individuals, and details of their generation could provide a roadmap for effective vaccination. Here we report the isolation, evolution and structure of a broadly neutralizing antibody from an African donor followed from time of infection. The mature antibody, CH103, neutralized ~55% of HIV-1 isolates, and its co-crystal structure with gp120 revealed a novel loop-based mechanism of CD4-binding site recognition. Virus and antibody gene sequencing revealed concomitant virus evolution and antibody maturation. Notably, the CH103-lineage unmutated common ancestor avidly bound the transmitted/founder HIV-1 envelope glycoprotein, and evolution of antibody neutralization breadth was preceded by extensive viral diversification in and near the CH103 epitope. These data elucidate the viral and antibody evolution leading to induction of a lineage of HIV-1 broadly neutralizing antibodies and provide insights into strategies to elicit similar antibodies via vaccination. PMID:23552890

Paleomagnetic and geochronologic constraints on the geodynamic evolution of the Central Dinarides

Science.gov (United States)

de Leeuw, Arjan; Mandic, Oleg; Krijgsman, Wout; Kuiper, Klaudia; Hrvatović, Hazim

2013-04-01

The geodynamic evolution of the Dinaride Mountains of southeastern Europe is relatively poorly understood, especially in comparison with the neighbouring Alps and Carpathians. We have constructed a new chronostratigraphy for the post-orogenic intra-montane basins of the Central Dinarides based on paleomagnetic and 40Ar/39Ar age data. Our results provide time constraints on the formation of these basins and elucidate their subsequent evolution. This is a fundamental step towards a better understanding of the late stage geodynamic evolution of the Central Dinarides. Our paleomagnetic results moreover indicate that the Dinarides have not experienced significant tectonic rotation since the late Oligocene. This implies that the Dinarides were decoupled from the adjacent Adria and the Tisza-Dacia Mega-Units that both underwent major rotation. We provide a reference frame for our rotation results through a review of Late Jurassic to Miocene paleomagnetic data, which elucidates spatial and tectonic rotation patterns in the Adria-Dinarides collision zone. The obtained results significantly improve our insight in the evolution of the Central Dinarides and help reconcile structural geological and paleomagnetic rotation estimates.

Increased tolerance towards serine obtained by adaptive laboratory evolution

DEFF Research Database (Denmark)

Mundhada, Hemanshu; Seoane, Jose Miguel; Koza, Anna

2014-01-01

The amino acid serine has previously been identified as one of the top 30 candidates of value added chemicals, making the production of serine from glucose attractive. Production of serine have previously been attempted in E. coli and C. glutamicum, however, titers sufficient for commercial...... by glyA), the conversion of serine to pyruvate (encoded by sdaA, sdaB and tdcG) was also deleted. As expected, the resulting strain turned out to be susceptible to even low concentrations of serine in the media. In order to improve the tolerance of the strain towards serine, adaptive laboratory evolution....... During the evolution experiment, the serine tolerance was increased substantially. Genome re-sequencing was subsequently used to analyze the genotype of a number of selected strains. These results reveal insights towards the adaptation process as well as the mechanism of serine tolerance....

Comparative genomics reveals conservative evolution of the xylem transcriptome in vascular plants.

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Li, Xinguo; Wu, Harry X; Southerton, Simon G

2010-06-21

Wood is a valuable natural resource and a major carbon sink. Wood formation is an important developmental process in vascular plants which played a crucial role in plant evolution. Although genes involved in xylem formation have been investigated, the molecular mechanisms of xylem evolution are not well understood. We use comparative genomics to examine evolution of the xylem transcriptome to gain insights into xylem evolution. The xylem transcriptome is highly conserved in conifers, but considerably divergent in angiosperms. The functional domains of genes in the xylem transcriptome are moderately to highly conserved in vascular plants, suggesting the existence of a common ancestral xylem transcriptome. Compared to the total transcriptome derived from a range of tissues, the xylem transcriptome is relatively conserved in vascular plants. Of the xylem transcriptome, cell wall genes, ancestral xylem genes, known proteins and transcription factors are relatively more conserved in vascular plants. A total of 527 putative xylem orthologs were identified, which are unevenly distributed across the Arabidopsis chromosomes with eight hot spots observed. Phylogenetic analysis revealed that evolution of the xylem transcriptome has paralleled plant evolution. We also identified 274 conifer-specific xylem unigenes, all of which are of unknown function. These xylem orthologs and conifer-specific unigenes are likely to have played a crucial role in xylem evolution. Conifers have highly conserved xylem transcriptomes, while angiosperm xylem transcriptomes are relatively diversified. Vascular plants share a common ancestral xylem transcriptome. The xylem transcriptomes of vascular plants are more conserved than the total transcriptomes. Evolution of the xylem transcriptome has largely followed the trend of plant evolution.

Cross-cultural Comparison of Learning in Human Hunting : Implications for Life History Evolution.

Science.gov (United States)

MacDonald, Katharine

2007-12-01

This paper is a cross-cultural examination of the development of hunting skills and the implications for the debate on the role of learning in the evolution of human life history patterns. While life history theory has proven to be a powerful tool for understanding the evolution of the human life course, other schools, such as cultural transmission and social learning theory, also provide theoretical insights. These disparate theories are reviewed, and alternative and exclusive predictions are identified. This study of cross-cultural regularities in how children learn hunting skills, based on the ethnographic literature on traditional hunters, complements existing empirical work and highlights future areas for investigation.

[Exploring the relationship between internalized stigma, insight and depression for inpatients with schizophrenia].

Science.gov (United States)

Bouvet, C; Bouchoux, A

2015-10-01

depression decreased moderately with CDSS and with small intensity with SAIQ, but clearly. So, ISMI is probably a mediating variable between IS and BDI-CDSS. In conclusion, internalized stigma could be a mediating variable between insight and depression. This validates our second hypothesis. Our results suggest that the relationship between insight and depression is mediated by internalized stigma. Patients with good insight who internalize stigma seem to be more depressed than those who don't. This result could have important consequences in clinical practice: improving insight level should be completed by a specific attention to the level and evolution of internalized stigma to avoid increasing depression. Further studies need to be conducted to confirm these results. Copyright © 2014 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

Understanding Cancer Genome and Its Evolution by Next Generation Sequencing

DEFF Research Database (Denmark)

Hou, Yong

Cancer will cause 13 million deaths by the year of 2030, ranking the second leading cause of death worldwide. Previous studies indicate that most of the cancers originate from cells that acquired somatic mutations and evolved as Darwin Theory. Ten biological insights of cancer have been summarized...... recently. Cutting-age technologies like next generation sequencing (NGS) enable exploring cancer genome and evolution much more efficiently. However, integrated cancer genome sequencing studies showed great inter-/intra-tumoral heterogeneity (ITH) and complex evolution patterns beyond the cancer biological...... knowledge we previously know. There is very limited knowledge of East Asia lung cancer genome except enrichment of EGFR mutations and lack of KRAS mutations. We carried out integrated genomic, transcriptomic and methylomic analysis of 335 primary Chinese lung adenocarcinomas (LUAD) and 35 corresponding...

Spectroscopic confirmation of an ultra-faint galaxy at the epoch of reionization

Science.gov (United States)

Hoag, Austin; Bradač, Maruša; Trenti, Michele; Treu, Tommaso; Schmidt, Kasper B.; Huang, Kuang-Han; Lemaux, Brian C.; He, Julie; Bernard, Stephanie R.; Abramson, Louis E.; Mason, Charlotte A.; Morishita, Takahiro; Pentericci, Laura; Schrabback, Tim

2017-04-01

Within one billion years of the Big Bang, intergalactic hydrogen was ionized by sources emitting ultraviolet and higher energy photons. This was the final phenomenon to globally affect all the baryons (visible matter) in the Universe. It is referred to as cosmic reionization and is an integral component of cosmology. It is broadly expected that intrinsically faint galaxies were the primary ionizing sources due to their abundance in this epoch1,2. However, at the highest redshifts (z > 7.5 lookback time 13.1 Gyr), all galaxies with spectroscopic confirmations to date are intrinsically bright and, therefore, not necessarily representative of the general population3. Here, we report the unequivocal spectroscopic detection of a low luminosity galaxy at z > 7.5. We detected the Lyman-α emission line at ˜10,504 Å in two separate observations with MOSFIRE4 on the Keck I Telescope and independently with the Hubble Space Telescope's slitless grism spectrograph, implying a source redshift of z = 7.640 ± 0.001. The galaxy is gravitationally magnified by the massive galaxy cluster MACS J1423.8+2404 (z = 0.545), with an estimated intrinsic luminosity of MAB = -19.6 ± 0.2 mag and a stellar mass of M⊙=3.0-0.8+1.5×108 solar masses. Both are an order of magnitude lower than the four other Lyman-α emitters currently known at z > 7.5, making it probably the most distant representative source of reionization found to date.

An Improved Statistical Point-source Foreground Model for the Epoch of Reionization

Energy Technology Data Exchange (ETDEWEB)

Murray, S. G.; Trott, C. M.; Jordan, C. H. [ARC Centre of Excellence for All-sky Astrophysics (CAASTRO) (Australia)

2017-08-10

We present a sophisticated statistical point-source foreground model for low-frequency radio Epoch of Reionization (EoR) experiments using the 21 cm neutral hydrogen emission line. Motivated by our understanding of the low-frequency radio sky, we enhance the realism of two model components compared with existing models: the source count distributions as a function of flux density and spatial position (source clustering), extending current formalisms for the foreground covariance of 2D power-spectral modes in 21 cm EoR experiments. The former we generalize to an arbitrarily broken power law, and the latter to an arbitrary isotropically correlated field. This paper presents expressions for the modified covariance under these extensions, and shows that for a more realistic source spatial distribution, extra covariance arises in the EoR window that was previously unaccounted for. Failure to include this contribution can yield bias in the final power-spectrum and under-estimate uncertainties, potentially leading to a false detection of signal. The extent of this effect is uncertain, owing to ignorance of physical model parameters, but we show that it is dependent on the relative abundance of faint sources, to the effect that our extension will become more important for future deep surveys. Finally, we show that under some parameter choices, ignoring source clustering can lead to false detections on large scales, due to both the induced bias and an artificial reduction in the estimated measurement uncertainty.

A New Method for Single-Epoch Ambiguity Resolution with Indoor Pseudolite Positioning.

Science.gov (United States)

Li, Xin; Zhang, Peng; Guo, Jiming; Wang, Jinling; Qiu, Weining

2017-04-21

Ambiguity resolution (AR) is crucial for high-precision indoor pseudolite positioning. Due to the existing characteristics of the pseudolite positioning system, such as the geometry structure of the stationary pseudolite which is consistently invariant, the indoor signal is easy to interrupt and the first order linear truncation error cannot be ignored, and a new AR method based on the idea of the ambiguity function method (AFM) is proposed in this paper. The proposed method is a single-epoch and nonlinear method that is especially well-suited for indoor pseudolite positioning. Considering the very low computational efficiency of conventional AFM, we adopt an improved particle swarm optimization (IPSO) algorithm to search for the best solution in the coordinate domain, and variances of a least squares adjustment is conducted to ensure the reliability of the solving ambiguity. Several experiments, including static and kinematic tests, are conducted to verify the validity of the proposed AR method. Numerical results show that the IPSO significantly improved the computational efficiency of AFM and has a more elaborate search ability compared to the conventional grid searching method. For the indoor pseudolite system, which had an initial approximate coordinate precision better than 0.2 m, the AFM exhibited good performances in both static and kinematic tests. With the corrected ambiguity gained from our proposed method, indoor pseudolite positioning can achieve centimeter-level precision using a low-cost single-frequency software receiver.

An Improved Statistical Point-source Foreground Model for the Epoch of Reionization

Science.gov (United States)

Murray, S. G.; Trott, C. M.; Jordan, C. H.

2017-08-01

We present a sophisticated statistical point-source foreground model for low-frequency radio Epoch of Reionization (EoR) experiments using the 21 cm neutral hydrogen emission line. Motivated by our understanding of the low-frequency radio sky, we enhance the realism of two model components compared with existing models: the source count distributions as a function of flux density and spatial position (source clustering), extending current formalisms for the foreground covariance of 2D power-spectral modes in 21 cm EoR experiments. The former we generalize to an arbitrarily broken power law, and the latter to an arbitrary isotropically correlated field. This paper presents expressions for the modified covariance under these extensions, and shows that for a more realistic source spatial distribution, extra covariance arises in the EoR window that was previously unaccounted for. Failure to include this contribution can yield bias in the final power-spectrum and under-estimate uncertainties, potentially leading to a false detection of signal. The extent of this effect is uncertain, owing to ignorance of physical model parameters, but we show that it is dependent on the relative abundance of faint sources, to the effect that our extension will become more important for future deep surveys. Finally, we show that under some parameter choices, ignoring source clustering can lead to false detections on large scales, due to both the induced bias and an artificial reduction in the estimated measurement uncertainty.

Interpretation of an Epoch in the Novel "the Big Green Tent" by L. Ulitskaya: Linguistic-Cultural Analysis of Verbal Lexicon

Directory of Open Access Journals (Sweden)

Ildar Ch. Safin

2017-11-01

Full Text Available This article is the verbal lexicon analysis based on the text of the novel "The Big Green Tent" by L. Ulitskaya. The creative manner of the contemporary writer attracts the attention of researchers, her writings describe the emotional experiences of the heroes and also give a generalized image of time full of historical details and features. The language of her stories and short stories is characterized by a special style in the description of time realities. A verb in the text allows the author to express the events and the circumstances that characterize an action in its dynamics due to the fact that verbal categories reflect the real reality in our consciousness. The method of linguistic cultural analysis of verbal lexicon in the novel "The Big Green Tent" made it possible to single out exactly those language units that the writer carefully selects for the creation and interpretation of the era. A special emphasis in the study is made on the creation of an expressive-emotional style of narration using the stylistic capabilities of the Russian verb. The individual author's methods of narration expressiveness creation are singled out: synonymous series, euphemisms, colloquial lexicon, etc. The conducted study and a careful analysis of the selected factual material testifies that, recreating an epoch, the master of the word invariably uses that language arsenal that brightly and fully conveys the color of time. L. Ulitskaya is able to be not only an indifferent witness of the epoch, but also her tenacious observer and interpreter. The analyzed factual material and the main points of this research can be used in the courses on stylistics and linguistic culturology, and also as an illustrative material during the classes on the linguistic analysis of a literary text.

Real-time forecasting of ICME shock arrivals at L1 during the "April Fool’s Day" epoch: 28 March – 21 April 2001

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W. Sun

Full Text Available The Sun was extremely active during the "April Fool’s Day" epoch of 2001. We chose this period between a solar flare on 28 March 2001 to a final shock arrival at Earth on 21 April 2001. The activity consisted of two presumed helmet-streamer blowouts, seven M-class flares, and nine X-class flares, the last of which was behind the west limb. We have been experimenting since February 1997 with real-time, end-to-end forecasting of interplanetary coronal mass ejection (ICME shock arrival times. Since August 1998, these forecasts have been distributed in real-time by e-mail to a list of interested scientists and operational USAF and NOAA forecasters. They are made using three different solar wind models. We describe here the solar events observed during the April Fool’s 2001 epoch, along with the predicted and actual shock arrival times, and the ex post facto correction to the real-time coronal shock speed observations. It appears that the initial estimates of coronal shock speeds from Type II radio burst observations and coronal mass ejections were too high by as much as 30%. We conclude that a 3-dimensional coronal density model should be developed for application to observations of solar flares and their Type II radio burst observations.

Key words. Interplanetary physics (flare and stream dynamics; interplanetary shocks – Magnetosheric physics (storms and substorms

Anisotropic evolution of 5D Friedmann-Robertson-Walker spacetime

International Nuclear Information System (INIS)

Middleton, Chad A.; Stanley, Ethan

2011-01-01

We examine the time evolution of the five-dimensional Einstein field equations subjected to a flat, anisotropic Robertson-Walker metric, where the 3D and higher-dimensional scale factors are allowed to dynamically evolve at different rates. By adopting equations of state relating the 3D and higher-dimensional pressures to the density, we obtain an exact expression relating the higher-dimensional scale factor to a function of the 3D scale factor. This relation allows us to write the Friedmann-Robertson-Walker field equations exclusively in terms of the 3D scale factor, thus yielding a set of 4D effective Friedmann-Robertson-Walker field equations. We examine the effective field equations in the general case and obtain an exact expression relating a function of the 3D scale factor to the time. This expression involves a hypergeometric function and cannot, in general, be inverted to yield an analytical expression for the 3D scale factor as a function of time. When the hypergeometric function is expanded for small and large arguments, we obtain a generalized treatment of the dynamical compactification scenario of Mohammedi [Phys. Rev. D 65, 104018 (2002)] and the 5D vacuum solution of Chodos and Detweiler [Phys. Rev. D 21, 2167 (1980)], respectively. By expanding the hypergeometric function near a branch point, we obtain the perturbative solution for the 3D scale factor in the small time regime. This solution exhibits accelerated expansion, which, remarkably, is independent of the value of the 4D equation of state parameter w. This early-time epoch of accelerated expansion arises naturally out of the anisotropic evolution of 5D spacetime when the pressure in the extra dimension is negative and offers a possible alternative to scalar field inflationary theory.

Coevolving parasites and population size shape the evolution of mating behaviour

Directory of Open Access Journals (Sweden)

Kerstes Niels AG

2013-02-01

Full Text Available Abstract Background Coevolution with parasites and population size are both expected to influence the evolution of mating rates. To gain insights into the interaction between these dual selective factors, we used populations from a coevolution experiment with the red flour beetle, Tribolium castaneum, and its microsporidian parasite, Nosema whitei. We maintained each experimental population at two different population sizes. We assayed the mating behaviour of both males and females from coevolved and paired non-coevolved control populations after 24 generations of coevolution with parasites. Results Males from large, coevolved populations (i.e. ancestors were exposed to parasites showed a reduced eagerness to mate compared to males from large, non-coevolved populations. But in small populations, coevolution did not lead to decreased male mating rates. Coevolved females from both large and small populations appeared to be more willing to accept mating than non-coevolved females. Conclusions This study provides unique, experimental insights into the combined roles of coevolving parasites and population size on the evolution of mating rate. Furthermore, we find that males and females respond differently to the same environmental conditions. Our results show that parasites can be key determinants of the sexual behaviour of their hosts.

Promoting entrepreneurship among informatics engineering students: insights from a case study

Science.gov (United States)

Fernandes, João M.; Afonso, Paulo; Fonte, Victor; Alves, Victor; Ribeiro, António Nestor

2017-01-01

Universities seek to promote entrepreneurship through effective education approaches, which need to be in permanent evolution. Nevertheless, the literature in entrepreneurship education lacks empirical evidence. This article discusses relevant issues related to promoting entrepreneurship in the software field, based on the experience of a 15-European Credit Transfer and Accumulation System course. This course seeks to instil in the students the recognition of the need to reconcile technical and business visions, organisational and commercial aspects, most of which have never been addressed previously. A series of semi-structured interviews made it possible to obtain relevant insights about the teaching-learning process underlying this course and its evolution over a seven-year period. Materials related with this course have been analysed, namely guidelines produced by the teachers and deliverables produced by the students. This article discusses the dimensions that were identified as fundamental for promoting entrepreneurship skills in the field of software, namely teamwork, project engagement, and contact with the market.

Evolution of MHC class I in the Order Crocodylia

DEFF Research Database (Denmark)

Jaratlerdsiri, Weerachai; Isberg, Sally R; Higgins, Damien P

2014-01-01

have mostly focused on model species. However, the investigation of this region in non-avian reptiles is still in its infancy. To provide insights into the evolutionary mechanisms that have shaped the diversity of this region in the Order Crocodylia, we investigated MHC class I exon 3, intron 3...... events of gene duplication, particularly in Crocodilidae. These findings enhance our understanding of MHC class I evolution and provide a preliminary framework for comparative studies of other non-avian reptiles as well as diversity assessment within Crocodylia....

Identifying Cis-Regulatory Changes Involved in the Evolution of Aerobic Fermentation in Yeasts

Science.gov (United States)

Lin, Zhenguo; Wang, Tzi-Yuan; Tsai, Bing-Shi; Wu, Fang-Ting; Yu, Fu-Jung; Tseng, Yu-Jung; Sung, Huang-Mo; Li, Wen-Hsiung

2013-01-01

Gene regulation change has long been recognized as an important mechanism for phenotypic evolution. We used the evolution of yeast aerobic fermentation as a model to explore how gene regulation has evolved and how this process has contributed to phenotypic evolution and adaptation. Most eukaryotes fully oxidize glucose to CO2 and H2O in mitochondria to maximize energy yield, whereas some yeasts, such as Saccharomyces cerevisiae and its relatives, predominantly ferment glucose into ethanol even in the presence of oxygen, a phenomenon known as aerobic fermentation. We examined the genome-wide gene expression levels among 12 different yeasts and found that a group of genes involved in the mitochondrial respiration process showed the largest reduction in gene expression level during the evolution of aerobic fermentation. Our analysis revealed that the downregulation of these genes was significantly associated with massive loss of binding motifs of Cbf1p in the fermentative yeasts. Our experimental assays confirmed the binding of Cbf1p to the predicted motif and the activator role of Cbf1p. In summary, our study laid a foundation to unravel the long-time mystery about the genetic basis of evolution of aerobic fermentation, providing new insights into understanding the role of cis-regulatory changes in phenotypic evolution. PMID:23650209

New probe of magnetic fields in the prereionization epoch. I. Formalism

Science.gov (United States)

Venumadhav, Tejaswi; Oklopčić, Antonija; Gluscevic, Vera; Mishra, Abhilash; Hirata, Christopher M.

2017-04-01

We propose a method of measuring extremely weak magnetic fields in the intergalactic medium prior to and during the epoch of cosmic reionization. The method utilizes the Larmor precession of spin-polarized neutral hydrogen in the triplet state of the hyperfine transition. This precession leads to a systematic change in the brightness temperature fluctuations of the 21-cm line from the high-redshift universe, and thus the statistics of these fluctuations encode information about the magnetic field the atoms are immersed in. The method is most suited to probing fields that are coherent on large scales; in this paper, we consider a homogenous magnetic field over the scale of the 21-cm fluctuations. Due to the long lifetime of the triplet state of the 21-cm transition, this technique is naturally sensitive to extremely weak field strengths, of order 10-19 G at a reference redshift of ˜20 (or 10-21 G if scaled to the present day). Therefore, this might open up the possibility of probing primordial magnetic fields just prior to reionization. If the magnetic fields are much stronger, it is still possible to use this method to infer their direction, and place a lower limit on their strength. In this paper (Paper I in a series on this effect), we perform detailed calculations of the microphysics behind this effect, and take into account all the processes that affect the hyperfine transition, including radiative decays, collisions, and optical pumping by Lyman-α photons. We conclude with an analytic formula for the brightness temperature of linear-regime fluctuations in the presence of a magnetic field, and discuss its limiting behavior for weak and strong fields.

Generative inference for cultural evolution.

Science.gov (United States)

Kandler, Anne; Powell, Adam

2018-04-05

One of the major challenges in cultural evolution is to understand why and how various forms of social learning are used in human populations, both now and in the past. To date, much of the theoretical work on social learning has been done in isolation of data, and consequently many insights focus on revealing the learning processes or the distributions of cultural variants that are expected to have evolved in human populations. In population genetics, recent methodological advances have allowed a greater understanding of the explicit demographic and/or selection mechanisms that underlie observed allele frequency distributions across the globe, and their change through time. In particular, generative frameworks-often using coalescent-based simulation coupled with approximate Bayesian computation (ABC)-have provided robust inferences on the human past, with no reliance on a priori assumptions of equilibrium. Here, we demonstrate the applicability and utility of generative inference approaches to the field of cultural evolution. The framework advocated here uses observed population-level frequency data directly to establish the likely presence or absence of particular hypothesized learning strategies. In this context, we discuss the problem of equifinality and argue that, in the light of sparse cultural data and the multiplicity of possible social learning processes, the exclusion of those processes inconsistent with the observed data might be the most instructive outcome. Finally, we summarize the findings of generative inference approaches applied to a number of case studies.This article is part of the theme issue 'Bridging cultural gaps: interdisciplinary studies in human cultural evolution'. © 2018 The Author(s).

Bioattractors: dynamical systems theory and the evolution of regulatory processes

Science.gov (United States)

Jaeger, Johannes; Monk, Nick

2014-01-01

In this paper, we illustrate how dynamical systems theory can provide a unifying conceptual framework for evolution of biological regulatory systems. Our argument is that the genotype–phenotype map can be characterized by the phase portrait of the underlying regulatory process. The features of this portrait – such as attractors with associated basins and their bifurcations – define the regulatory and evolutionary potential of a system. We show how the geometric analysis of phase space connects Waddington's epigenetic landscape to recent computational approaches for the study of robustness and evolvability in network evolution. We discuss how the geometry of phase space determines the probability of possible phenotypic transitions. Finally, we demonstrate how the active, self-organizing role of the environment in phenotypic evolution can be understood in terms of dynamical systems concepts. This approach yields mechanistic explanations that go beyond insights based on the simulation of evolving regulatory networks alone. Its predictions can now be tested by studying specific, experimentally tractable regulatory systems using the tools of modern systems biology. A systematic exploration of such systems will enable us to understand better the nature and origin of the phenotypic variability, which provides the substrate for evolution by natural selection. PMID:24882812

Metagenomic insights into evolution of heavy metal-contaminated groundwater microbial community

Energy Technology Data Exchange (ETDEWEB)

Hemme, C.L.; Deng, Y.; Gentry, T.J.; Fields, M.W.; Wu, L.; Barua, S.; Barry, K.; Green-Tringe, S.; Watson, D.B.; He, Z.; Hazen, T.C.; Tiedje, J.M.; Rubin, E.M.; Zhou, J.

2010-07-01

Understanding adaptation of biological communities to environmental change is a central issue in ecology and evolution. Metagenomic analysis of a stressed groundwater microbial community reveals that prolonged exposure to high concentrations of heavy metals, nitric acid and organic solvents ({approx}50 years) has resulted in a massive decrease in species and allelic diversity as well as a significant loss of metabolic diversity. Although the surviving microbial community possesses all metabolic pathways necessary for survival and growth in such an extreme environment, its structure is very simple, primarily composed of clonal denitrifying {gamma}- and {beta}-proteobacterial populations. The resulting community is overabundant in key genes conferring resistance to specific stresses including nitrate, heavy metals and acetone. Evolutionary analysis indicates that lateral gene transfer could have a key function in rapid response and adaptation to environmental contamination. The results presented in this study have important implications in understanding, assessing and predicting the impacts of human-induced activities on microbial communities ranging from human health to agriculture to environmental management, and their responses to environmental changes.

Analyses of pig genomes provide insight into porcine demography and evolution

Science.gov (United States)

Groenen, Martien A. M.; Archibald, Alan L.; Uenishi, Hirohide; Tuggle, Christopher K.; Takeuchi, Yasuhiro; Rothschild, Max F.; Rogel-Gaillard, Claire; Park, Chankyu; Milan, Denis; Megens, Hendrik-Jan; Li, Shengting; Larkin, Denis M.; Kim, Heebal; Frantz, Laurent A. F.; Caccamo, Mario; Ahn, Hyeonju; Aken, Bronwen L.; Anselmo, Anna; Anthon, Christian; Auvil, Loretta; Badaoui, Bouabid; Beattie, Craig W.; Bendixen, Christian; Berman, Daniel; Blecha, Frank; Blomberg, Jonas; Bolund, Lars; Bosse, Mirte; Botti, Sara; Bujie, Zhan; Bystrom, Megan; Capitanu, Boris; Silva, Denise Carvalho; Chardon, Patrick; Chen, Celine; Cheng, Ryan; Choi, Sang-Haeng; Chow, William; Clark, Richard C.; Clee, Christopher; Crooijmans, Richard P. M. A.; Dawson, Harry D.; Dehais, Patrice; De Sapio, Fioravante; Dibbits, Bert; Drou, Nizar; Du, Zhi-Qiang; Eversole, Kellye; Fadista, João; Fairley, Susan; Faraut, Thomas; Faulkner, Geoffrey J.; Fowler, Katie E.; Fredholm, Merete; Fritz, Eric; Gilbert, James G. R.; Giuffra, Elisabetta; Gorodkin, Jan; Griffin, Darren K.; Harrow, Jennifer L.; Hayward, Alexander; Howe, Kerstin; Hu, Zhi-Liang; Humphray, Sean J.; Hunt, Toby; Hornshøj, Henrik; Jeon, Jin-Tae; Jern, Patric; Jones, Matthew; Jurka, Jerzy; Kanamori, Hiroyuki; Kapetanovic, Ronan; Kim, Jaebum; Kim, Jae-Hwan; Kim, Kyu-Won; Kim, Tae-Hun; Larson, Greger; Lee, Kyooyeol; Lee, Kyung-Tai; Leggett, Richard; Lewin, Harris A.; Li, Yingrui; Liu, Wansheng; Loveland, Jane E.; Lu, Yao; Lunney, Joan K.; Ma, Jian; Madsen, Ole; Mann, Katherine; Matthews, Lucy; McLaren, Stuart; Morozumi, Takeya; Murtaugh, Michael P.; Narayan, Jitendra; Nguyen, Dinh Truong; Ni, Peixiang; Oh, Song-Jung; Onteru, Suneel; Panitz, Frank; Park, Eung-Woo; Park, Hong-Seog; Pascal, Geraldine; Paudel, Yogesh; Perez-Enciso, Miguel; Ramirez-Gonzalez, Ricardo; Reecy, James M.; Zas, Sandra Rodriguez; Rohrer, Gary A.; Rund, Lauretta; Sang, Yongming; Schachtschneider, Kyle; Schraiber, Joshua G.; Schwartz, John; Scobie, Linda; Scott, Carol; Searle, Stephen; Servin, Bertrand; Southey, Bruce R.; Sperber, Goran; Stadler, Peter; Sweedler, Jonathan V.; Tafer, Hakim; Thomsen, Bo; Wali, Rashmi; Wang, Jian; Wang, Jun; White, Simon; Xu, Xun; Yerle, Martine; Zhang, Guojie; Zhang, Jianguo; Zhang, Jie; Zhao, Shuhong; Rogers, Jane; Churcher, Carol; Schook, Lawrence B.

2013-01-01

For 10,000 years pigs and humans have shared a close and complex relationship. From domestication to modern breeding practices, humans have shaped the genomes of domestic pigs. Here we present the assembly and analysis of the genome sequence of a female domestic Duroc pig (Sus scrofa) and a comparison with the genomes of wild and domestic pigs from Europe and Asia. Wild pigs emerged in South East Asia and subsequently spread across Eurasia. Our results reveal a deep phylogenetic split between European and Asian wild boars ~1 million years ago, and a selective sweep analysis indicates selection on genes involved in RNA processing and regulation. Genes associated with immune response and olfaction exhibit fast evolution. Pigs have the largest repertoire of functional olfactory receptor genes, reflecting the importance of smell in this scavenging animal. The pig genome sequence provides an important resource for further improvements of this important livestock species, and our identification of many putative disease-causing variants extends the potential of the pig as a biomedical model. PMID:23151582

The mating type locus (MAT and sexual reproduction of Cryptococcus heveanensis: insights into the evolution of sex and sex-determining chromosomal regions in fungi.

Directory of Open Access Journals (Sweden)

Banu Metin

2010-05-01

transitions in sexuality concomitant with emergence of a pathogenic clade. These studies provide insight into convergent processes that independently punctuated evolution of sex-determining loci and sex chromosomes in fungi, plants, and animals.

THE BARYON CYCLE AT HIGH REDSHIFTS: EFFECTS OF GALACTIC WINDS ON GALAXY EVOLUTION IN OVERDENSE AND AVERAGE REGIONS

Energy Technology Data Exchange (ETDEWEB)

Sadoun, Raphael [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112-0830 (United States); Shlosman, Isaac; Choi, Jun-Hwan; Romano-Díaz, Emilio, E-mail: raphael.sadoun@utah.edu [Department of Physics and Astronomy, University of Kentucky, Lexington, KY 40506-0055 (United States)

2016-10-01

We employ high-resolution cosmological zoom-in simulations focusing on a high-sigma peak and an average cosmological field at z ∼ 6–12 in order to investigate the influence of environment and baryonic feedback on galaxy evolution in the reionization epoch. Strong feedback, e.g., galactic winds, caused by elevated star formation rates (SFRs) is expected to play an important role in this evolution. We compare different outflow prescriptions: (i) constant wind velocity (CW), (ii) variable wind scaling with galaxy properties (VW), and (iii) no outflows (NW). The overdensity leads to accelerated evolution of dark matter and baryonic structures, absent from the “normal” region, and to shallow galaxy stellar mass functions at the low-mass end. Although CW shows little dependence on the environment, the more physically motivated VW model does exhibit this effect. In addition, VW can reproduce the observed specific SFR (sSFR) and the sSFR–stellar mass relation, which CW and NW fail to satisfy simultaneously. Winds also differ substantially in affecting the state of the intergalactic medium (IGM). The difference lies in the volume-filling factor of hot, high-metallicity gas, which is near unity for CW, while such gas remains confined in massive filaments for VW, and locked up in galaxies for NW. Such gas is nearly absent from the normal region. Although all wind models suffer from deficiencies, the VW model seems to be promising in correlating the outflow properties with those of host galaxies. Further constraints on the state of the IGM at high z are needed to separate different wind models.

The 2010 Eyja eruption evolution by using IR satellite sensors measurements: retrieval comparison and insights into explosive volcanic processes

Science.gov (United States)

Piscini, A.; Corradini, S.; Merucci, L.; Scollo, S.

2010-12-01

The 2010 April-May Eyja eruption caused an unprecedented disruption to economic, political and cultural activities in Europe and across the world. Because of the harming effects of fine ash particles on aircrafts, many European airports were in fact closed causing millions of passengers to be stranded, and with a worldwide airline industry loss estimated of about 2.5 billion Euros. Both security and economical issues require robust and affordable volcanic cloud retrievals that may be really improved through the intercomparison among different remote sensing instruments. In this work the Thermal InfraRed (TIR) measurements of different polar and geostationary satellites instruments as the Moderate Resolution Imaging Spectroradiometer (MODIS), the Advanced Very High Resolution Radiometer (AVHRR) and the Spin Enhanced Visible and Infrared Imager (SEVIRI), have been used to retrieve the volcanic ash and SO2 in the entire eruption period over Iceland. The ash retrievals (mass, AOD and effective radius) have been carried out by means of the split window BTD technique using the channels centered around 11 and 12 micron. The least square fit procedure is used for the SO2 retrieval by using the 7.3 and 8.7 micron channels. The simulated TOA radiance Look-Up Table (LUT) needed for both the ash and SO2 column abundance retrievals have been computed using the MODTRAN 4 Radiative Transfer Model. Further, the volcanic plume column altitude and ash density have been computed and compared, when available, with ground observations. The results coming from the retrieval of different IR sensors show a good agreement over the entire eruption period. The column height, the volcanic ash and the SO2 emission trend confirm the indentified different phases occurred during the Eyja eruption. We remark that the retrieved volcanic plume evolution can give important insights into eruptive dynamics during long-lived explosive activity.

From PPROM to caul: The evolution of membrane rupture in mammals

Directory of Open Access Journals (Sweden)

Gregory Stempfle

2013-12-01

Full Text Available Rupture of the extraembryonic membranes that form the gestational sac in humans is a typical feature of human parturition. However, preterm premature rupture of membranes (PPROM occurs in approximately 1% of pregnancies, and is a leading cause of preterm birth. Conversely, retention of an intact gestational sac during parturition in the form of a caul is a rare occurrence. Understanding the molecular and evolutionary underpinnings of these disparate phenotypes can provide insight into both normal pregnancy and PPROM. Using phylogenetic techniques we reconstructed the evolution of the gestational sac phenotype at parturition in 55 mammal species representing all major viviparous mammal groups. We infer the ancestral state in therians, eutherians, and primates, as in humans, is a ruptured gestational sac at parturition. We present evidence that intact membranes at parturition have evolved convergently in diverse mammals including horses, elephants, and bats. In order to gain insight into the molecular underpinnings of the evolution of enhanced membrane integrity we also used comparative genomics techniques to reconstruct the evolution of a subset of genes implicated in PPROM, and find that four genes (ADAMTS2, COL1A1, COL5A1, LEPRE1 show significant evidence of increased nonsynonymous rates of substitution on lineages with intact membranes as compared to those with ruptured membranes. Among these genes, we also discovered that 17 human SNPs are associated with or near amino acid replacement sites in those mammals with intact membranes. These SNPs are candidate functional variants within humans, which may play roles in both PPROM and/or the retention of the gestational sac at birth.

Co-evolution of Industry Strategies and Government Policies: The Case of the Brazilian Automotive Industry

Directory of Open Access Journals (Sweden)

Roberto Gonzalez Duarte

2017-07-01

Full Text Available This study examines the evolution of the automotive industry in Brazil and its key drivers. We argue that the rules of the game – industry policies – are an outcome of exchanges between the host government and industry. These arise from changes in economic and political environments and interdependence between industry and the country’s economy. To this end, we draw upon literature on institutions and co-evolution to understand the industry footprint over a 50-year period, as well as its relationship with changes in government policies. This study generates new insights on institutional and co-evolution political perspectives by showing that the rules of the game are not only the making of the government, but are also the result of interdependencies between industry and government.

Pechukas-Yukawa approach to the evolution of the quantum state of a parametrically perturbed system

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Qureshi, Mumnuna A.; Zhong, Johnny; Qureshi, Zihad; Mason, Peter; Betouras, Joseph J.; Zagoskin, Alexandre M.

2018-03-01

We consider the evolution of the quantum states of a Hamiltonian that is parametrically perturbed via a term proportional to the adiabatic parameter λ (t ) . Starting with the Pechukas-Yukawa mapping of the energy eigenvalue evolution in a generalized Calogero-Sutherland model of a one-dimensional classical gas, we consider the adiabatic approximation with two different expansions of the quantum state in powers of d λ /d t and compare them with a direct numerical simulation. We show that one of these expansions (Magnus series) is especially convenient for the description of nonadiabatic evolution of the system. Applying the expansion to the exact cover 3-satisfiability problem, we obtain the occupation dynamics, which provides insight into the population of states and sources of decoherence in a quantum system.

Objective characterization of bruise evolution using photothermal depth profiling and Monte Carlo modeling

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Vidovič, Luka; Milanič, Matija; Majaron, Boris

2015-01-01

Pulsed photothermal radiometry (PPTR) allows noninvasive determination of laser-induced temperature depth profiles in optically scattering layered structures. The obtained profiles provide information on spatial distribution of selected chromophores such as melanin and hemoglobin in human skin. We apply the described approach to study time evolution of incidental bruises (hematomas) in human subjects. By combining numerical simulations of laser energy deposition in bruised skin with objective fitting of the predicted and measured PPTR signals, we can quantitatively characterize the key processes involved in bruise evolution (i.e., hemoglobin mass diffusion and biochemical decomposition). Simultaneous analysis of PPTR signals obtained at various times post injury provides an insight into the variations of these parameters during the bruise healing process. The presented methodology and results advance our understanding of the bruise evolution and represent an important step toward development of an objective technique for age determination of traumatic bruises in forensic medicine.

Genomics, transcriptomics and proteomics: enabling insights into social evolution and disease challenges for managed and wild bees.

Science.gov (United States)

Trapp, Judith; McAfee, Alison; Foster, Leonard J

2017-02-01

Globally, there are over 20 000 bee species (Hymenoptera: Apoidea: Anthophila) with a host of biologically fascinating characteristics. Although they have long been studied as models for social evolution, recent challenges to bee health (mainly diseases and pesticides) have gathered the attention of both public and research communities. Genome sequences of twelve bee species are now complete or under progress, facilitating the application of additional 'omic technologies. Here, we review recent developments in honey bee and native bee research in the genomic era. We discuss the progress in genome sequencing and functional annotation, followed by the enabled comparative genomics, proteomics and transcriptomics applications regarding social evolution and health. Finally, we end with comments on future challenges in the postgenomic era. © 2016 John Wiley & Sons Ltd.

On the contribution of active galactic nuclei to the diffuse X-ray background

International Nuclear Information System (INIS)

Avni, Y.

1977-01-01

It is shown that cosmological evolution has a pronounced effect on the contributions of active galactic nuclei to the diffuse x-ray background. The dependence of such contributions on the form and amount of density evolution, on the deceleration parameter, and on the formation epoch is found. It is established, in particular, that x-ray Seyferts can account for all of the observed 2-10 keV background when the effects of evolution are considered; the required amount of evolution is intermediate between the evolution of quasars and no evolution. (author)

On the contribution of active galactic nuclei to the diffuse X-ray background

International Nuclear Information System (INIS)

Avni, Y.

1978-01-01

We show that cosmological evolution has a pronounced effect on the contributions of active galactic nuclei to the diffuse x-ray background. We find the dependence of such contributions on the form and amount of density evolution, on the deceleration parameter, and on the formation epoch. We find in particular that x-ray Seyferts can account for all of the observed 2-10 keV background when the effects of evolution are considered; the required amount of evolution is intermediate between the evolution of quasars and no evolution. (orig.) [de

THE WYOMING SURVEY FOR Hα. II. Hα LUMINOSITY FUNCTIONS AT z∼ 0.16, 0.24, 0.32, AND 0.40

International Nuclear Information System (INIS)

Dale, Daniel A.; Cook, David O.; Moore, Carolynn A.; Staudaher, Shawn M.; Barlow, Rebecca J.; Cohen, Seth A.; Johnson, L. Clifton; Kattner, ShiAnne M.; Schuster, Micah D.

2010-01-01

The Wyoming Survey for Hα, or WySH, is a large-area, ground-based imaging survey for Hα-emitting galaxies at redshifts of z ∼ 0.16, 0.24, 0.32, and 0.40. The survey spans up to 4 deg 2 in a set of fields of low Galactic cirrus emission, using twin narrowband filters at each epoch for improved stellar continuum subtraction. Hα luminosity functions are presented for each Δz ∼ 0.02 epoch based on a total of nearly 1200 galaxies. These data clearly show an evolution with look-back time in the volume-averaged cosmic star formation rate. Integrals of Schechter fits to the incompleteness- and extinction-corrected Hα luminosity functions indicate star formation rates per comoving volume of 0.010, 0.013, 0.020, 0.022 h 70 M sun yr -1 Mpc -3 at z ∼ 0.16, 0.24, 0.32, and 0.40, respectively. Combined statistical and systematic measurement uncertainties are on the order of 25%, while the effects of cosmic variance are at the 20% level. The bulk of this evolution is driven by changes in the characteristic luminosity L * of the Hα luminosity functions, with L * for the earlier two epochs being a factor of 2 larger than L * at the latter two epochs; it is more difficult with this data set to decipher systematic evolutionary differences in the luminosity function amplitude and faint-end slope. Coupling these results with a comprehensive compilation of results from the literature on emission line surveys, the evolution in the cosmic star formation rate density over 0 ∼< z ∼< 1.5 is measured.

Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins.

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Poth, Aaron G; Colgrave, Michelle L; Philip, Reynold; Kerenga, Bomai; Daly, Norelle L; Anderson, Marilyn A; Craik, David J

2011-04-15

Cyclotides are plant proteins whose defining structural features are a head-to-tail cyclized backbone and three interlocking disulfide bonds, which in combination are known as a cyclic cystine knot. This unique structural motif confers cyclotides with exceptional resistance to proteolysis. Their endogenous function is thought to be as plant defense agents, associated with their insecticidal and larval growth-inhibitory properties. However, in addition, an array of pharmaceutically relevant biological activities has been ascribed to cyclotides, including anti-HIV, anthelmintic, uterotonic, and antimicrobial effects. So far, >150 cyclotides have been elucidated from members of the Rubiaceae, Violaceae, and Cucurbitaceae plant families, but their wider distribution among other plant families remains unclear. Clitoria ternatea (Butterfly pea) is a member of plant family Fabaceae and through its usage in traditional medicine to aid childbirth bears similarity to Oldenlandia affinis, from which many cyclotides have been isolated. Using a combination of nanospray and matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) analyses, we examined seed extracts of C. ternatea and discovered cyclotides in the Fabaceae, the third-largest family of flowering plants. We characterized 12 novel cyclotides, thus expanding knowledge of cyclotide distribution and evolution within the plant kingdom. The discovery of cyclotides containing novel sequence motifs near the in planta cyclization site has provided new insights into cyclotide biosynthesis. In particular, MS analyses of the novel cyclotides from C. ternatea suggest that Asn to Asp variants at the cyclization site are more common than previously recognized. Moreover, this study provides impetus for the examination of other economically and agriculturally significant species within Fabaceae, now the largest plant family from which cyclotides have been described.

THE IMACS CLUSTER BUILDING SURVEY. III. THE STAR FORMATION HISTORIES OF FIELD GALAXIES

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Oemler, Augustus Jr.; Dressler, Alan [Observatories of the Carnegie Institution for Science, 813 Santa Barbara St., Pasadena, CA 91101-1292 (United States); Gladders, Michael G.; Abramson, Louis [Department of Astronomy and Astrophysics, University of Chicago, Chicago, IL 60637 (United States); Fritz, Jacopo [Sterrenkundig Observatorium, Universiteit Gent, Krijgslaan 281 S9, B-9000 Gent (Belgium); Poggianti, Bianca M.; Vulcani, Benedetta [INAF-Osservatorio Astronomico di Padova, vicolo dell' Osservatorio 5, I-35122 Padova (Italy)

2013-06-10

Using data from the IMACS Cluster Building Survey and from nearby galaxy surveys, we examine the evolution of the rate of star formation in field galaxies from z = 0.60 to the present. Fitting the luminosity function to a standard Schechter form, we find a rapid evolution of M{sub B}{sup *} consistent with that found in other deep surveys; at the present epoch M{sub B}{sup *} is evolving at the rate of 0.38 Gyr{sup -1}, several times faster than the predictions of simple models for the evolution of old, coeval galaxies. The evolution of the distribution of specific star formation rates (SSFRs) is also too rapid to explain by such models. We demonstrate that starbursts cannot, even in principle, explain the evolution of the SSFR distribution. However, the rapid evolution of both M{sub B}{sup *} and the SSFR distribution can be explained if some fraction of galaxies have star formation rates characterized by both short rise and fall times and by an epoch of peak star formation more recent than the majority of galaxies. Although galaxies of every stellar mass up to 1.4 Multiplication-Sign 10{sup 11} M{sub Sun} show a range of epochs of peak star formation, the fraction of ''younger'' galaxies falls from about 40% at a mass of 4 Multiplication-Sign 10{sup 10} M{sub Sun} to zero at a mass of 1.4 Multiplication-Sign 10{sup 11} M{sub Sun }. The incidence of younger galaxies appears to be insensitive to the density of the local environment; but does depend on group membership: relatively isolated galaxies are much more likely to be young than are group members.

A model and solving algorithm of combination planning for weapon equipment based on Epoch-era analysis method

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Wang, Meng; Zhang, Huaiqiang; Zhang, Kan

2017-10-01

Focused on the circumstance that the equipment using demand in the short term and the development demand in the long term should be made overall plans and took into consideration in the weapons portfolio planning and the practical problem of the fuzziness in the definition of equipment capacity demand. The expression of demand is assumed to be an interval number or a discrete number. With the analysis method of epoch-era, a long planning cycle is broke into several short planning cycles with different demand value. The multi-stage stochastic programming model is built aimed at maximize long-term planning cycle demand under the constraint of budget, equipment development time and short planning cycle demand. The scenario tree is used to discretize the interval value of the demand, and genetic algorithm is designed to solve the problem. At last, a case is studied to demonstrate the feasibility and effectiveness of the proposed mode.

Organic Chemostratigraphic Markers Characteristic of the (Informally Designated) Anthropocene Epoch

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Kruge, M. A.

2008-12-01

Recognizing the tremendous collective impact of humans on the environment in the industrial age, the proposed designation of the current time period as the Anthropocene Epoch has considerable merit. One of the signature activities during this time continues to be the intensive extraction, processing, and combustion of fossil fuels. While fossil fuels themselves are naturally-occurring, they are most often millions of years old and associated with deeply buried strata. They may be found at the surface, for example, as natural oil seeps or coal seam outcrops, but these are relatively rare occurrences. Fossil fuels and their myriad by- products become the source of distinctive organic chemostratigraphic marker compounds for the Anthropocene when they occur out of their original geological context, i.e., as widespread contaminants in sediments and soils. These persistent compounds have high long-term preservation potential, particularly when deposited under low oxygen conditions. Fossil fuels can occur as environmental contaminants in raw form (e.g., crude petroleum spilled during transport) or as manufactured products (e.g., diesel oil from a leaking storage facility, coal tar from a manufactured gas plant, plastic waste in a landfill, pesticides from petroleum feedstock in agricultural soils). Distinctive assemblages of hydrocarbon marker compounds including acyclic isoprenoids, hopanes, and steranes can be readily detected by gas chromatography/mass spectrometric analysis of surface sediments and soils. Polycyclic aromatic hydrocarbons (PAHs), along with sulfur-, oxygen-, and nitrogen-containing aromatic compounds, are also characteristic of fossil fuels and are readily detectable as well. More widespread is the airfall deposition of fossil fuel combustion products from vehicular, domestic and industrial sources. These occur in higher concentrations in large urban centers, but are also detected in remote areas. Parent (nonmethylated) PAHs such as phenanthrene

Was the Sun especially active at the end of the late glacial epoch?

Science.gov (United States)

Alekseeva, Liliya

In their pioneering work, the geophysicists A. Brekke and A. Egeland (1983) collected beliefs of different peoples, associated with northern lights. Our analyses of this collection show that these beliefs are mainly related to the mythological idea of ``abnormal'' deads (dead, childless old maids in Finnish beliefs; killed people; spirits dangerous to children). We find similar motifs in Slavic fairy tales about the ``Thrice-Nine Land,'' regarded as the other world in folkloric studies (in the Land where mobile and agitated warlike girls live, whose Head Girl is characterized by the words ``white snow, pretty light, the prettiest in the World,'' but whose name ``Mariya Morevna'' refers to the word ``mort''; where a river flows with its banks covered by human bones; where the witch Baba-Yaga dwells, being extremely dangerous for children). Moreover, it can be noted that similar narrative fabulous myths deal with the concept of auroral oval northern lights, since some specific features of the natural auroral forms are mentioned there, with their particular spatial orientations (to the North or West). This resembles the manner in which Ancient Greek myths describe the real properties of the heavenly phenomena in a mythological language. It is interesting that myths on the high-latitude northern lights spread even to the South of Europe (and, might be, to India and Iran). This fact can be understood in view of the following. It has been established that, during the late glacial epoch, the environmental and cultural conditions were similar over the area from Pyrenean to the Ural Mountains; the pattern of hunters' settlements outlined the glacial sheet from the outside. Relics of the hunters' beliefs can now be found in Arctic, where the environment and lifestyle remain nearly unchanged. The ethnographer Yu.B. Simchenko (1976) has reconstructed the most archaic Arctic myths. According to them, the World of dead is associated with the world of ice governed by the ``Ice

Ecology and evolution in microbial systems: the generation and maintenance of diversity in phage-host interactions.

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Jessup, Christine M; Forde, Samantha E

2008-06-01

Insights gained from studying the interactions between viruses and bacteria have important implications for the ecology and evolution of virus-host interactions in many environments and for pathogen-host and predator-prey interactions in general. Here, we focus on the generation and maintenance of diversity, highlighting recent laboratory and field experiments with microorganisms.

Hormones and the Evolution of Complex Traits: Insights from Artificial Selection on Behavior.

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Garland, Theodore; Zhao, Meng; Saltzman, Wendy

2016-08-01

Although behavior may often be a fairly direct target of natural or sexual selection, it cannot evolve without changes in subordinate traits that cause or permit its expression. In principle, changes in endocrine function could be a common mechanism underlying behavioral evolution because they are well positioned to mediate integrated responses to behavioral selection. More specifically, hormones can influence both motivational (e.g., brain) and performance (e.g., muscles) components of behavior simultaneously and in a coordinated fashion. If the endocrine system is often "used" as a general mechanism to effect responses to selection, then correlated responses in other aspects of behavior, life history, and organismal performance (e.g., locomotor abilities) should commonly occur because any cell with appropriate receptors could be affected. Ways in which behavior coadapts with other aspects of the phenotype can be studied directly through artificial selection and experimental evolution. Several studies have targeted rodent behavior for selective breeding and reported changes in other aspects of behavior, life history, and lower-level effectors of these organismal traits, including endocrine function. One example involves selection for high levels of voluntary wheel running, one aspect of physical activity, in four replicate High Runner (HR) lines of mice. Circulating levels of several hormones (including insulin, testosterone, thyroxine, triiodothyronine) have been characterized, three of which-corticosterone, leptin, and adiponectin-differ between HR and control lines, depending on sex, age, and generation. Potential changes in circulating levels of other behaviorally and metabolically relevant hormones, as well as in other components of the endocrine system (e.g., receptors), have yet to be examined. Overall, results to date identify promising avenues for further studies on the endocrine basis of activity levels. © The Author 2016. Published by Oxford University

Theory of mind correlates with clinical insight but not cognitive insight in patients with schizophrenia.

Science.gov (United States)

Zhang, Qi; Li, Xu; Parker, Giverny J; Hong, Xiao-Hong; Wang, Yi; Lui, Simon S Y; Neumann, David L; Cheung, Eric F C; Shum, David H K; Chan, Raymond C K

2016-03-30

Research on the relationship between insight and social cognition, in particular Theory of Mind (ToM), in schizophrenia has yielded mixed findings to date. Very few studies, however, have assessed both clinical insight and cognitive insight when examining their relationships with ToM in schizophrenia. The current study thus investigated the relationship between clinical insight, cognitive insight, and ToM in a sample of 56 patients with schizophrenia and 30 healthy controls. Twenty-seven patients were classified as low in clinical insight according to their scores on the 'insight' item (G12) of the Positive and Negative Syndrome Scale (PANSS). Moreover, cognitive insight and ToM were assessed with the Beck Cognitive Insight Scale (BCIS) and the Yoni task, respectively. The results indicated that patients with poor clinical insight performed worse on tasks of second-order cognitive and affective ToM, while the ToM performance of patients with high clinical insight was equivalent to that of healthy controls. Furthermore, while clinical insight was correlated with ToM and clinical symptoms, cognitive insight did not correlate with clinical insight, ToM, or clinical symptoms. Clinical insight thus appears to be an important factor related to ToM in schizophrenia. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Evolution of the metazoan mitochondrial replicase.

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Oliveira, Marcos T; Haukka, Jani; Kaguni, Laurie S

2015-03-03

The large number of complete mitochondrial DNA (mtDNA) sequences available for metazoan species makes it a good system for studying genome diversity, although little is known about the mechanisms that promote and/or are correlated with the evolution of this organellar genome. By investigating the molecular evolutionary history of the catalytic and accessory subunits of the mtDNA polymerase, pol γ, we sought to develop mechanistic insight into its function that might impact genome structure by exploring the relationships between DNA replication and animal mitochondrial genome diversity. We identified three evolutionary patterns among metazoan pol γs. First, a trend toward stabilization of both sequence and structure occurred in vertebrates, with both subunits evolving distinctly from those of other animal groups, and acquiring at least four novel structural elements, the most important of which is the HLH-3β (helix-loop-helix, 3 β-sheets) domain that allows the accessory subunit to homodimerize. Second, both subunits of arthropods and tunicates have become shorter and evolved approximately twice as rapidly as their vertebrate homologs. And third, nematodes have lost the gene for the accessory subunit, which was accompanied by the loss of its interacting domain in the catalytic subunit of pol γ, and they show the highest rate of molecular evolution among all animal taxa. These findings correlate well with the mtDNA genomic features of each group described above, and with their modes of DNA replication, although a substantive amount of biochemical work is needed to draw conclusive links regarding the latter. Describing the parallels between evolution of pol γ and metazoan mtDNA architecture may also help in understanding the processes that lead to mitochondrial dysfunction and to human disease-related phenotypes. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Upper Limits on the 21 cm Epoch of Reionization Power Spectrum from One Night with LOFAR

Science.gov (United States)

Patil, A. H.; Yatawatta, S.; Koopmans, L. V. E.; de Bruyn, A. G.; Brentjens, M. A.; Zaroubi, S.; Asad, K. M. B.; Hatef, M.; Jelić, V.; Mevius, M.; Offringa, A. R.; Pandey, V. N.; Vedantham, H.; Abdalla, F. B.; Brouw, W. N.; Chapman, E.; Ciardi, B.; Gehlot, B. K.; Ghosh, A.; Harker, G.; Iliev, I. T.; Kakiichi, K.; Majumdar, S.; Mellema, G.; Silva, M. B.; Schaye, J.; Vrbanec, D.; Wijnholds, S. J.

2017-03-01

We present the first limits on the Epoch of Reionization 21 cm H I power spectra, in the redshift range z = 7.9-10.6, using the Low-Frequency Array (LOFAR) High-Band Antenna (HBA). In total, 13.0 hr of data were used from observations centered on the North Celestial Pole. After subtraction of the sky model and the noise bias, we detect a non-zero {{{Δ }}}{{I}}2={(56+/- 13{mK})}2 (1-σ) excess variance and a best 2-σ upper limit of {{{Δ }}}212< {(79.6{mK})}2 at k = 0.053 h cMpc-1 in the range z = 9.6-10.6. The excess variance decreases when optimizing the smoothness of the direction- and frequency-dependent gain calibration, and with increasing the completeness of the sky model. It is likely caused by (I) residual side-lobe noise on calibration baselines, (II) leverage due to nonlinear effects, (III) noise and ionosphere-induced gain errors, or a combination thereof. Further analyses of the excess variance will be discussed in forthcoming publications.

New limits on 21 cm epoch of reionization from paper-32 consistent with an x-ray heated intergalactic medium at z = 7.7

Energy Technology Data Exchange (ETDEWEB)

Parsons, Aaron R.; Liu, Adrian; Ali, Zaki S.; Pober, Jonathan C. [Astronomy Department, University of California, Berkeley, CA (United States); Aguirre, James E.; Moore, David F. [Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA (United States); Bradley, Richard F. [Department of Electrical and Computer Engineering, University of Virginia, Charlottesville, VA (United States); Carilli, Chris L. [National Radio Astronomy Observatory, Socorro, NM (United States); DeBoer, David R.; Dexter, Matthew R.; MacMahon, David H. E. [Radio Astronomy Laboratory, University of California, Berkeley, CA (United States); Gugliucci, Nicole E. [Department of Astronomy, University of Virginia, Charlottesville, VA (United States); Jacobs, Daniel C. [School of Earth and Space Exploration, Arizona State University, Tempe, AZ (United States); Klima, Pat [National Radio Astronomy Observatory, Charlottesville, VA (United States); Manley, Jason R.; Walbrugh, William P. [Square Kilometer Array, South Africa Project, Cape Town (South Africa); Stefan, Irina I. [Cavendish Laboratory, Cambridge (United Kingdom)

2014-06-20

We present new constraints on the 21 cm Epoch of Reionization (EoR) power spectrum derived from three months of observing with a 32 antenna, dual-polarization deployment of the Donald C. Backer Precision Array for Probing the Epoch of Reionization in South Africa. In this paper, we demonstrate the efficacy of the delay-spectrum approach to avoiding foregrounds, achieving over eight orders of magnitude of foreground suppression (in mK{sup 2}). Combining this approach with a procedure for removing off-diagonal covariances arising from instrumental systematics, we achieve a best 2σ upper limit of (41 mK){sup 2} for k = 0.27 h Mpc{sup –1} at z = 7.7. This limit falls within an order of magnitude of the brighter predictions of the expected 21 cm EoR signal level. Using the upper limits set by these measurements, we generate new constraints on the brightness temperature of 21 cm emission in neutral regions for various reionization models. We show that for several ionization scenarios, our measurements are inconsistent with cold reionization. That is, heating of the neutral intergalactic medium (IGM) is necessary to remain consistent with the constraints we report. Hence, we have suggestive evidence that by z = 7.7, the H I has been warmed from its cold primordial state, probably by X-rays from high-mass X-ray binaries or miniquasars. The strength of this evidence depends on the ionization state of the IGM, which we are not yet able to constrain. This result is consistent with standard predictions for how reionization might have proceeded.

New limits on 21 cm epoch of reionization from paper-32 consistent with an x-ray heated intergalactic medium at z = 7.7

International Nuclear Information System (INIS)

Parsons, Aaron R.; Liu, Adrian; Ali, Zaki S.; Pober, Jonathan C.; Aguirre, James E.; Moore, David F.; Bradley, Richard F.; Carilli, Chris L.; DeBoer, David R.; Dexter, Matthew R.; MacMahon, David H. E.; Gugliucci, Nicole E.; Jacobs, Daniel C.; Klima, Pat; Manley, Jason R.; Walbrugh, William P.; Stefan, Irina I.

2014-01-01

We present new constraints on the 21 cm Epoch of Reionization (EoR) power spectrum derived from three months of observing with a 32 antenna, dual-polarization deployment of the Donald C. Backer Precision Array for Probing the Epoch of Reionization in South Africa. In this paper, we demonstrate the efficacy of the delay-spectrum approach to avoiding foregrounds, achieving over eight orders of magnitude of foreground suppression (in mK 2 ). Combining this approach with a procedure for removing off-diagonal covariances arising from instrumental systematics, we achieve a best 2σ upper limit of (41 mK) 2 for k = 0.27 h Mpc –1 at z = 7.7. This limit falls within an order of magnitude of the brighter predictions of the expected 21 cm EoR signal level. Using the upper limits set by these measurements, we generate new constraints on the brightness temperature of 21 cm emission in neutral regions for various reionization models. We show that for several ionization scenarios, our measurements are inconsistent with cold reionization. That is, heating of the neutral intergalactic medium (IGM) is necessary to remain consistent with the constraints we report. Hence, we have suggestive evidence that by z = 7.7, the H I has been warmed from its cold primordial state, probably by X-rays from high-mass X-ray binaries or miniquasars. The strength of this evidence depends on the ionization state of the IGM, which we are not yet able to constrain. This result is consistent with standard predictions for how reionization might have proceeded.

Nature(andculture in the anthropocene epoch

Directory of Open Access Journals (Sweden)

Grażyna Gajewska

2012-01-01

Full Text Available The article deals with a New Understanding of nature and culture, which is being crystallized in the intellectual current defined by the name of post-humanities. The starting point for the analysis of work of art from the area of bioart – transgenic plant named Edunia, which is a part of a larger project Natural History of the Enigma. Edunia, which does not occur in nature but was created by the artist Eduardo Kac by means of specialists in the field of genetic engineering. A new form of life defined as plantimal shows a DNA expression of the artist included into decorative flowers of petunia. Rose petals of flowers are “interspersed” by dark red vessels the feature of which is the expression of Kac’s gene; this because the artist took care of that that his DNA was found just in the venation of the flower. In the article I present two interpretation paths of this work of bioart which, however, are not a sharp counterpoint to one another, but somewhat differently place accents between nature and culture in their mutual entanglements. One of these paths may be defined as an attempt at making others realise or reminding them about our evolutional species condition, while the other one as an attempt at treating nature as an important actor of the sociopolitical activities.

Star formation in globular clusters and dwarf galaxies and implications for the early evolution of galaxies

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Lin, Douglas N. C.; Murray, Stephen D.

1991-01-01

Based upon the observed properties of globular clusters and dwarf galaxies in the Local Group, we present important theoretical constraints on star formation in these systems. These constraints indicate that protoglobular cluster clouds had long dormant periods and a brief epoch of violent star formation. Collisions between protocluster clouds triggered fragmentation into individual stars. Most protocluster clouds dispersed into the Galactic halo during the star formation epoch. In contrast, the large spread in stellar metallicity in dwarf galaxies suggests that star formation in their pregenitors was self-regulated: we propose the protocluster clouds formed from thermal instability in the protogalactic clouds and show that a population of massive stars is needed to provide sufficient UV flux to prevent the collapsing protogalactic clouds from fragmenting into individual stars. Based upon these constraints, we propose a unified scenario to describe the early epochs of star formation in the Galactic halo as well as the thick and thin components of the Galactic disk.

Nematode and arthropod genomes provide new insights into the evolution of class 2 B1 GPCRs.

Science.gov (United States)

Cardoso, João C R; Félix, Rute C; Power, Deborah M

2014-01-01

Nematodes and arthropods are the most speciose animal groups and possess Class 2 B1 G-protein coupled receptors (GPCRs). Existing models of invertebrate Class 2 B1 GPCR evolution are mainly centered on Caenorhabditis elegans and Drosophila melanogaster and a few other nematode and arthropod representatives. The present study reevaluates the evolution of metazoan Class 2 B1 GPCRs and orthologues by exploring the receptors in several nematode and arthropod genomes and comparing them to the human receptors. Three novel receptor phylogenetic clusters were identified and designated cluster A, cluster B and PDF-R-related cluster. Clusters A and B were identified in several nematode and arthropod genomes but were absent from D. melanogaster and Culicidae genomes, whereas the majority of the members of the PDF-R-related cluster were from nematodes. Cluster A receptors were nematode and arthropod-specific but shared a conserved gene environment with human receptor loci. Cluster B members were orthologous to human GCGR, PTHR and Secretin members with which they probably shared a common origin. PDF-R and PDF-R related clusters were present in representatives of both nematodes and arthropods. The results of comparative analysis of GPCR evolution and diversity in protostomes confirm previous notions that C. elegans and D. melanogaster genomes are not good representatives of nematode and arthropod phyla. We hypothesize that at least four ancestral Class 2 B1 genes emerged early in the metazoan radiation, which after the protostome-deuterostome split underwent distinct selective pressures that resulted in duplication and deletion events that originated the current Class 2 B1 GPCRs in nematode and arthropod genomes.

Effects of conformism on the cultural evolution of social behaviour.

Directory of Open Access Journals (Sweden)

Lucas Molleman

Full Text Available Models of cultural evolution study how the distribution of cultural traits changes over time. The dynamics of cultural evolution strongly depends on the way these traits are transmitted between individuals by social learning. Two prominent forms of social learning are payoff-based learning (imitating others that have higher payoffs and conformist learning (imitating locally common behaviours. How payoff-based and conformist learning affect the cultural evolution of cooperation is currently a matter of lively debate, but few studies systematically analyse the interplay of these forms of social learning. Here we perform such a study by investigating how the interaction of payoff-based and conformist learning affects the outcome of cultural evolution in three social contexts. First, we develop a simple argument that provides insights into how the outcome of cultural evolution will change when more and more conformist learning is added to payoff-based learning. In a social dilemma (e.g. a Prisoner's Dilemma, conformism can turn cooperation into a stable equilibrium; in an evasion game (e.g. a Hawk-Dove game or a Snowdrift game conformism tends to destabilize the polymorphic equilibrium; and in a coordination game (e.g. a Stag Hunt game, conformism changes the basin of attraction of the two equilibria. Second, we analyse a stochastic event-based model, revealing that conformism increases the speed of cultural evolution towards pure equilibria. Individual-based simulations as well as the analysis of the diffusion approximation of the stochastic model by and large confirm our findings. Third, we investigate the effect of an increasing degree of conformism on cultural group selection in a group-structured population. We conclude that, in contrast to statements in the literature, conformism hinders rather than promotes the evolution of cooperation.

Effects of conformism on the cultural evolution of social behaviour.

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Molleman, Lucas; Pen, Ido; Weissing, Franz J

2013-01-01

Models of cultural evolution study how the distribution of cultural traits changes over time. The dynamics of cultural evolution strongly depends on the way these traits are transmitted between individuals by social learning. Two prominent forms of social learning are payoff-based learning (imitating others that have higher payoffs) and conformist learning (imitating locally common behaviours). How payoff-based and conformist learning affect the cultural evolution of cooperation is currently a matter of lively debate, but few studies systematically analyse the interplay of these forms of social learning. Here we perform such a study by investigating how the interaction of payoff-based and conformist learning affects the outcome of cultural evolution in three social contexts. First, we develop a simple argument that provides insights into how the outcome of cultural evolution will change when more and more conformist learning is added to payoff-based learning. In a social dilemma (e.g. a Prisoner's Dilemma), conformism can turn cooperation into a stable equilibrium; in an evasion game (e.g. a Hawk-Dove game or a Snowdrift game) conformism tends to destabilize the polymorphic equilibrium; and in a coordination game (e.g. a Stag Hunt game), conformism changes the basin of attraction of the two equilibria. Second, we analyse a stochastic event-based model, revealing that conformism increases the speed of cultural evolution towards pure equilibria. Individual-based simulations as well as the analysis of the diffusion approximation of the stochastic model by and large confirm our findings. Third, we investigate the effect of an increasing degree of conformism on cultural group selection in a group-structured population. We conclude that, in contrast to statements in the literature, conformism hinders rather than promotes the evolution of cooperation.

Molecular electronics: insight from first-principles transport simulations.

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Paulsson, Magnus; Frederiksen, Thomas; Brandbyge, Mads

2010-01-01

Conduction properties of nanoscale contacts can be studied using first-principles simulations. Such calculations give insight into details behind the conductance that is not readily available in experiments. For example, we may learn how the bonding conditions of a molecule to the electrodes affect the electronic transport. Here we describe key computational ingredients and discuss these in relation to simulations for scanning tunneling microscopy (STM) experiments with C60 molecules where the experimental geometry is well characterized. We then show how molecular dynamics simulations may be combined with transport calculations to study more irregular situations, such as the evolution of a nanoscale contact with the mechanically controllable break-junction technique. Finally we discuss calculations of inelastic electron tunnelling spectroscopy as a characterization technique that reveals information about the atomic arrangement and transport channels.

The surface and interior evolution of Ceres revealed by fractures and secondary crater chains

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Scully, Jennifer E. C.; Buczkowski, Debra; Schmedemann, Nico; King, Scott; O'Brien, David P.; Castillo-Rogez, Julie; Raymond, Carol; Marchi, Simone; Russell, Christopher T.; Mitri, Giuseppe; Bland, Michael T.

2016-10-01

Dawn became the first spacecraft to visit and orbit Ceres, a dwarf planet and the largest body in the asteroid belt (radius ~470 km) (Russell et al., 2016). Before Dawn's arrival, telescopic observations and thermal evolution modeling indicated Ceres was differentiated, with an average density of 2,100 kg/m3 (e.g. McCord & Sotin, 2005; Castillo-Rogez & McCord, 2010). Moreover, pervasive viscous relaxation in a water-ice-rich outer layer was predicted to erase most features on Ceres' surface (Bland, 2013). However, a full understanding of Ceres' surface and interior evolution remained elusive. On the basis of global geologic mapping, we identify prevalent ≥1 km wide linear features that formed: 1) as the surface expression of subsurface fractures, and 2) as material ejected during impact-crater formation impacted and scoured the surface, forming secondary crater chains. The formation and preservation of these linear features indicates Ceres' outer layer is relatively strong, and is not dominated by viscous relaxation as predicted. The fractures also give us insights into Ceres' interior: their spacing indicates the fractured layer is ~30 km thick, and we interpret the fractures formed because of uplift and extension induced by an upwelling region, which is consistent with geodynamic modeling (King et al., 2016). In addition, we find that some secondary crater chains do not form radial patterns around their source impact craters, and are located in a different hemisphere from their source impact craters, because of Ceres' fast rotation (period of ~9 hours) and relatively small radius. Our results show Ceres has a surface and outer layer with characteristics that are different than predicted, and underwent complex surface and interior evolution. Our fuller understanding of Ceres, based on Dawn data, gives us important insights into the evolution of bodies in the asteroid belt, and provides unique constraints that can be used to evaluate predictions of the surface

On the Evolution of the Mammalian Brain.

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Torday, John S; Miller, William B

2016-01-01

Hobson and Friston have hypothesized that the brain must actively dissipate heat in order to process information (Hobson et al., 2014). This physiologic trait is functionally homologous with the first instantation of life formed by lipids suspended in water forming micelles- allowing the reduction in entropy (heat dissipation). This circumvents the Second Law of Thermodynamics permitting the transfer of information between living entities, enabling them to perpetually glean information from the environment, that is felt by many to correspond to evolution per se. The next evolutionary milestone was the advent of cholesterol, embedded in the cell membranes of primordial eukaryotes, facilitating metabolism, oxygenation and locomotion, the triadic basis for vertebrate evolution. Lipids were key to homeostatic regulation of calcium, forming calcium channels. Cell membrane cholesterol also fostered metazoan evolution by forming lipid rafts for receptor-mediated cell-cell signaling, the origin of the endocrine system. The eukaryotic cell membrane exapted to all complex physiologic traits, including the lung and brain, which are molecularly homologous through the function of neuregulin, mediating both lung development and myelinization of neurons. That cooption later exapted as endothermy during the water-land transition (Torday, 2015a), perhaps being the functional homolog for brain heat dissipation and conscious/mindful information processing. The skin and brain similarly share molecular homologies through the "skin-brain" hypothesis, giving insight to the cellular-molecular "arc" of consciousness from its unicellular origins to integrated physiology. This perspective on the evolution of the central nervous system clarifies self-organization, reconciling thermodynamic and informational definitions of the underlying biophysical mechanisms, thereby elucidating relations between the predictive capabilities of the brain and self-organizational processes.

The evolution of offensive realism.

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Johnson, Dominic D P; Phil, D; Thayer, Bradley A

Offensive realism, a theory of international relations, holds that states are disposed to competition and conflict because they are self-interested, power maximizing, and fearful of other states. Moreover, it argues that states are obliged to behave this way because doing so favors survival in the international system. Debate continues as to whether modern states actually do, or should, behave in this way, but we are struck by a different question. In this article, we ask whether the three core assumptions about behavior in offensive realism-self-help, power maximization, and outgroup fear-have any basis in scientific knowledge about human behavioral evolution. We find that these precise traits are not only evolutionarily adaptive but also empirically common across the animal kingdom, especially in primate and human societies. Based on these findings, we hypothesize that states behave as offensive realists predict not just because of anarchy in the modern international system but also because of the legacy of our evolution. In short, offensive realism may really be describing the nature of the human species more than the nature of the international system. If our hypothesis is correct, then evolutionary theory offers the following: (1) a novel ultimate cause of offensive realist behavior; (2) an extension of offensive realism to any domain in which humans compete for power; and (3) an explanation for why individual leaders themselves, and not just states, seek power. However, a key insight from evolution is that the primacy of self-help, power maximization, and outgroup fear does not necessarily condemn individuals or groups to competition and conflict; rather, these traits can in themselves give rise to cooperation and alliances.

The evolution of blood pressure and the rise of mankind.

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Schulte, Kevin; Kunter, Uta; Moeller, Marcus J

2015-05-01

Why is it that only human beings continuously perform acts of heroism? Looking back at our evolutionary history can offer us some potentially useful insight. This review highlights some of the major steps in our evolution-more specifically, the evolution of high blood pressure. When we were fish, the first kidney was developed to create a standardized internal 'milieu' preserving the primordial sea within us. When we conquered land as amphibians, the evolution of the lung required a low systemic blood pressure, which explains why early land vertebrates (amphibians, reptiles) are such low performers. Gaining independence from water required the evolution of an impermeable skin and a water-retaining kidney. The latter was accomplished twice with two different solutions in the two major branches of vertebrate evolution: mammals excrete nitrogenous waste products as urea, which can be utilized by the kidney as an osmotic agent to produce more concentrated urine. Dinosaurs and birds have a distinct nitrogen metabolism and excrete nitrogen as water-insoluble uric acid-therefore, their kidneys cannot use urea to concentrate as well. Instead, some birds have developed the capability to reabsorb water from their cloacae. The convergent development of a separate small circulation of the lung in mammals and birds allowed for the evolution of 'high blood-pressure animals' with better capillarization of the peripheral tissues allowing high endurance performance. Finally, we investigate why mankind outperforms any other mammal on earth and why, to this day, we continue to perform acts of heroism on our eternal quest for personal bliss. © The Author 2014. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.

Unique genome organization of non-mammalian papillomaviruses provides insights into the evolution of viral early proteins.

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Van Doorslaer, Koenraad; Ruoppolo, Valeria; Schmidt, Annie; Lescroël, Amelie; Jongsomjit, Dennis; Elrod, Megan; Kraberger, Simona; Stainton, Daisy; Dugger, Katie M; Ballard, Grant; Ainley, David G; Varsani, Arvind

2017-07-01

estimated the divergence time between Northern fulmar-associated papillomavirus and the other Sauropsid papillomaviruses be to around 250 million years ago, during the Paleozoic-Mesozoic transition and our analysis dates the root of the papillomavirus tree between 400 and 600 million years ago. Our analysis shows evidence for niche adaptation and that these non-mammalian viruses have highly divergent E6 and E7 proteins, providing insights into the evolution of the early viral (onco-)proteins.

Unique genome organization of non-mammalian papillomaviruses provides insights into the evolution of viral early proteins

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Van Doorslaer, Koenraad; Ruoppolo, Valeria; Schmidt, Annie; Lescroël, Amelie; Jongsomjit, Dennis; Elrod, Megan; Kraberger, Simona; Stainton, Daisy; Dugger, Katie M.; Ballard, Grant; Ainley, David G.; Varsani, Arvind

2017-01-01

divergence time between Northern fulmar-associated papillomavirus and the other Sauropsid papillomaviruses be to around 250 million years ago, during the Paleozoic-Mesozoic transition and our analysis dates the root of the papillomavirus tree between 400 and 600 million years ago. Our analysis shows evidence for niche adaptation and that these non-mammalian viruses have highly divergent E6 and E7 proteins, providing insights into the evolution of the early viral (onco-)proteins.

Hydrologic and Agent-based Modelling of Hydro-refugia in East Africa, Insights into the Importance of Water Resources in Hominin Evolution and Dispersal

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Ashley, G. M.; Cuthbert, M. O.; Gleeson, T. P.; Reynolds, S. R.; Bennett, M. R.; Newton, A. C.; McCormack, C. J.

2017-12-01

Hominin evolution and climate variability have often been linked because of the apparent coincidence of climate fluctuations and speciation or extinctions, although the cause and effect of climate on natural selection is not clear. Climate in the EARS (East African Rift System) where most hominin first occurrences are located experienced an overall drying over the last 7 myr. Superimposed on this trend, Milankovitch cycles generated wet-dry precession cycles ( 23 kyr) that changed both water and food resource availability. During dry periods, lakes became more alkaline and rivers ephemeral but, groundwater, buffered from surface climate effects, remained a potential resource during the driest of times. The possibility of widespread groundwater sources hydro-refugia, such as springs, wetlands and groundwater-fed perennial streams has received little attention with respect to the paleoenvironmental context of hominin evolution or dispersal. We demonstrate that hydrogeological modelling of the modern landscape in East Africa coupled with ABM (agent-based modelling) of hominin movement yields new insight into potential correlates of hominin survival and dispersal. Digitized hydrological mapping of present day rivers, lakes and springs along the EARS (2000 km) from northern Tanzania to Ethiopia provided the modelling framework. Present day conditions are considered analogous to past dry periods; wet period conditions are an expanded hydrologic network including all surface water bodies. Our focus was on perennial springs discharging at 1,000 m3/y (volume to sustain a small wetland). 450 such springs occur and were found to be significantly controlled by geology, not just climate. The ABM was designed to determine if it was possible for humans to walk between hydro-refugia in 3 days. Four climate scenarios were run on ABM: wet, wet-to-dry, dry and dry-to-wet. During dry periods our results suggest that groundwater availability would have been critical to supporting

Insight Is Not in the Problem: Investigating Insight in Problem Solving across Task Types.

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Webb, Margaret E; Little, Daniel R; Cropper, Simon J

2016-01-01

The feeling of insight in problem solving is typically associated with the sudden realization of a solution that appears obviously correct (Kounios et al., 2006). Salvi et al. (2016) found that a solution accompanied with sudden insight is more likely to be correct than a problem solved through conscious and incremental steps. However, Metcalfe (1986) indicated that participants would often present an inelegant but plausible (wrong) answer as correct with a high feeling of warmth (a subjective measure of closeness to solution). This discrepancy may be due to the use of different tasks or due to different methods in the measurement of insight (i.e., using a binary vs. continuous scale). In three experiments, we investigated both findings, using many different problem tasks (e.g., Compound Remote Associates, so-called classic insight problems, and non-insight problems). Participants rated insight-related affect (feelings of Aha-experience, confidence, surprise, impasse, and pleasure) on continuous scales. As expected we found that, for problems designed to elicit insight, correct solutions elicited higher proportions of reported insight in the solution compared to non-insight solutions; further, correct solutions elicited stronger feelings of insight compared to incorrect solutions.

The mean free path of hydrogen ionizing photons during the epoch of reionization

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Rahmati, Alireza; Schaye, Joop

2018-05-01

We use the Aurora radiation-hydrodynamical simulations to study the mean free path (MFP) for hydrogen ionizing photons during the epoch of reionization. We directly measure the MFP by averaging the distance 1 Ry photons travel before reaching an optical depth of unity along random lines-of-sight. During reionization the free paths tend to end in neutral gas with densities near the cosmic mean, while after reionization the end points tend to be overdense but highly ionized. Despite the increasing importance of discrete, over-dense systems, the cumulative contribution of systems with NHI ≲ 1016.5 cm-2 suffices to drive the MFP at z ≈ 6, while at earlier times higher column densities are more important. After reionization the typical size of HI systems is close to the local Jeans length, but during reionization it is much larger. The mean free path for photons originating close to galaxies, {MFP_{gal}}, is much smaller than the cosmic MFP. After reionization this enhancement can remain significant up to starting distances of ˜1 comoving Mpc. During reionization, however, {MFP_{gal}} for distances ˜102 - 103 comoving kpc typically exceeds the cosmic MFP. These findings have important consequences for models that interpret the intergalactic MFP as the distance escaped ionizing photons can travel from galaxies before being absorbed and may cause them to under-estimate the required escape fraction from galaxies, and/or the required emissivity of ionizing photons after reionization.

ARECIBO MULTI-EPOCH H I ABSORPTION MEASUREMENTS AGAINST PULSARS: TINY-SCALE ATOMIC STRUCTURE

International Nuclear Information System (INIS)

Stanimirovic, S.; Weisberg, J. M.; Pei, Z.; Tuttle, K.; Green, J. T.

2010-01-01

We present results from multi-epoch neutral hydrogen (H I) absorption observations of six bright pulsars with the Arecibo telescope. Moving through the interstellar medium (ISM) with transverse velocities of 10-150 AU yr -1 , these pulsars have swept across 1-200 AU over the course of our experiment, allowing us to probe the existence and properties of the tiny-scale atomic structure (TSAS) in the cold neutral medium (CNM). While most of the observed pulsars show no significant change in their H I absorption spectra, we have identified at least two clear TSAS-induced opacity variations in the direction of B1929+10. These observations require strong spatial inhomogeneities in either the TSAS clouds' physical properties themselves or else in the clouds' galactic distribution. While TSAS is occasionally detected on spatial scales down to 10 AU, it is too rare to be characterized by a spectrum of turbulent CNM fluctuations on scales of 10 1 -10 3 AU, as previously suggested by some work. In the direction of B1929+10, an apparent correlation between TSAS and interstellar clouds inside the warm Local Bubble (LB) indicates that TSAS may be tracing the fragmentation of the LB wall via hydrodynamic instabilities. While similar fragmentation events occur frequently throughout the ISM, the warm medium surrounding these cold cloudlets induces a natural selection effect wherein small TSAS clouds evaporate quickly and are rare, while large clouds survive longer and become a general property of the ISM.

ATLAS BASEMAPS IN WEB 2.0 EPOCH

Directory of Open Access Journals (Sweden)

V. Chabaniuk

2016-06-01

Full Text Available The authors have analyzed their experience of the production of various Electronic Atlases (EA and Atlas Information Systems (AtIS of so-called "classical type". These EA/AtIS have been implemented in the past decade in the Web 1.0 architecture (e.g., National Atlas of Ukraine, Atlas of radioactive contamination of Ukraine, and others. One of the main distinguishing features of these atlases was their static nature - the end user could not change the content of EA/AtIS. Base maps are very important element of any EA/AtIS. In classical type EA/AtIS they were static datasets, which consisted of two parts: the topographic data of a fixed scale and data of the administrative-territorial division of Ukraine. It is important to note that the technique of topographic data production was based on the use of direct channels of topographic entity observation (such as aerial photography for the selected scale. Changes in the information technology of the past half-decade are characterized by the advent of the “Web 2.0 epoch”. Due to this, in cartography appeared such phenomena as, for example, "neo-cartography" and various mapping platforms like OpenStreetMap. These changes have forced developers of EA/AtIS to use new atlas basemaps. Our approach is described in the article. The phenomenon of neo-cartography and/or Web 2.0 cartography are analysed by authors using previously developed Conceptual framework of EA/AtIS. This framework logically explains the cartographic phenomena relations of three formations: Web 1.0, Web 1.0x1.0 and Web 2.0. Atlas basemaps of the Web 2.0 epoch are integrated information systems. We use several ways to integrate separate atlas basemaps into the information system – by building: weak integrated information system, structured system and meta-system. This integrated information system consists of several basemaps and falls under the definition of "big data". In real projects it is already used the basemaps of three strata

The correlation function for density perturbations in an expanding universe. IV - The evolution of the correlation function. [galaxy distribution

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Mcclelland, J.; Silk, J.

1979-01-01

The evolution of the two-point correlation function for the large-scale distribution of galaxies in an expanding universe is studied on the assumption that the perturbation densities lie in a Gaussian distribution centered on any given mass scale. The perturbations are evolved according to the Friedmann equation, and the correlation function for the resulting distribution of perturbations at the present epoch is calculated. It is found that: (1) the computed correlation function gives a satisfactory fit to the observed function in cosmological models with a density parameter (Omega) of approximately unity, provided that a certain free parameter is suitably adjusted; (2) the power-law slope in the nonlinear regime reflects the initial fluctuation spectrum, provided that the density profile of individual perturbations declines more rapidly than the -2.4 power of distance; and (3) both positive and negative contributions to the correlation function are predicted for cosmological models with Omega less than unity.

A novel insight into the cost-benefit model for the evolution of botanical carnivory.

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Pavlovič, Andrej; Saganová, Michaela

2015-06-01

The cost-benefit model for the evolution of botanical carnivory provides a conceptual framework for interpreting a wide range of comparative and experimental studies on carnivorous plants. This model assumes that the modified leaves called traps represent a significant cost for the plant, and this cost is outweighed by the benefits from increased nutrient uptake from prey, in terms of enhancing the rate of photosynthesis per unit leaf mass or area (AN) in the microsites inhabited by carnivorous plants. This review summarizes results from the classical interpretation of the cost-benefit model for evolution of botanical carnivory and highlights the costs and benefits of active trapping mechanisms, including water pumping, electrical signalling and accumulation of jasmonates. Novel alternative sequestration strategies (utilization of leaf litter and faeces) in carnivorous plants are also discussed in the context of the cost-benefit model. Traps of carnivorous plants have lower AN than leaves, and the leaves have higher AN after feeding. Prey digestion, water pumping and electrical signalling represent a significant carbon cost (as an increased rate of respiration, RD) for carnivorous plants. On the other hand, jasmonate accumulation during the digestive period and reprogramming of gene expression from growth and photosynthesis to prey digestion optimizes enzyme production in comparison with constitutive secretion. This inducibility may have evolved as a cost-saving strategy beneficial for carnivorous plants. The similarities between plant defence mechanisms and botanical carnivory are highlighted. © The Author 2015. Published by Oxford University Press on behalf of the Annals of Botany Company. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The genome of the obligate intracellular parasite Trachipleistophora hominis: new insights into microsporidian genome dynamics and reductive evolution.

Directory of Open Access Journals (Sweden)

Eva Heinz

Full Text Available The dynamics of reductive genome evolution for eukaryotes living inside other eukaryotic cells are poorly understood compared to well-studied model systems involving obligate intracellular bacteria. Here we present 8.5 Mb of sequence from the genome of the microsporidian Trachipleistophora hominis, isolated from an HIV/AIDS patient, which is an outgroup to the smaller compacted-genome species that primarily inform ideas of evolutionary mode for these enormously successful obligate intracellular parasites. Our data provide detailed information on the gene content, genome architecture and intergenic regions of a larger microsporidian genome, while comparative analyses allowed us to infer genomic features and metabolism of the common ancestor of the species investigated. Gene length reduction and massive loss of metabolic capacity in the common ancestor was accompanied by the evolution of novel microsporidian-specific protein families, whose conservation among microsporidians, against a background of reductive evolution, suggests they may have important functions in their parasitic lifestyle. The ancestor had already lost many metabolic pathways but retained glycolysis and the pentose phosphate pathway to provide cytosolic ATP and reduced coenzymes, and it had a minimal mitochondrion (mitosome making Fe-S clusters but not ATP. It possessed bacterial-like nucleotide transport proteins as a key innovation for stealing host-generated ATP, the machinery for RNAi, key elements of the early secretory pathway, canonical eukaryotic as well as microsporidian-specific regulatory elements, a diversity of repetitive and transposable elements, and relatively low average gene density. Microsporidian genome evolution thus appears to have proceeded in at least two major steps: an ancestral remodelling of the proteome upon transition to intracellular parasitism that involved reduction but also selective expansion, followed by a secondary compaction of genome

Parallel Evolution of Sperm Hyper-Activation Ca2+ Channels.

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Cooper, Jacob C; Phadnis, Nitin

2017-07-01

Sperm hyper-activation is a dramatic change in sperm behavior where mature sperm burst into a final sprint in the race to the egg. The mechanism of sperm hyper-activation in many metazoans, including humans, consists of a jolt of Ca2+ into the sperm flagellum via CatSper ion channels. Surprisingly, all nine CatSper genes have been independently lost in several animal lineages. In Drosophila, sperm hyper-activation is performed through the cooption of the polycystic kidney disease 2 (pkd2) Ca2+ channel. The parallels between CatSpers in primates and pkd2 in Drosophila provide a unique opportunity to examine the molecular evolution of the sperm hyper-activation machinery in two independent, nonhomologous calcium channels separated by > 500 million years of divergence. Here, we use a comprehensive phylogenomic approach to investigate the selective pressures on these sperm hyper-activation channels. First, we find that the entire CatSper complex evolves rapidly under recurrent positive selection in primates. Second, we find that pkd2 has parallel patterns of adaptive evolution in Drosophila. Third, we show that this adaptive evolution of pkd2 is driven by its role in sperm hyper-activation. These patterns of selection suggest that the evolution of the sperm hyper-activation machinery is driven by sexual conflict with antagonistic ligands that modulate channel activity. Together, our results add sperm hyper-activation channels to the class of fast evolving reproductive proteins and provide insights into the mechanisms used by the sexes to manipulate sperm behavior. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

LONG-LIVED CHAOTIC ORBITAL EVOLUTION OF EXOPLANETS IN MEAN MOTION RESONANCES WITH MUTUAL INCLINATIONS

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Barnes, Rory; Deitrick, Russell; Quinn, Thomas R. [Astronomy Department, University of Washington, Box 951580, Seattle, WA 98195 (United States); Greenberg, Richard [Lunar and Planetary Laboratory, University of Arizona, 1629 E. University Boulevard, Tucson, AZ 86716 (United States); Raymond, Sean N., E-mail: rory@astro.washington.edu [NASA Astrobiology Institute-Virtual Planetary Laboratory Lead Team (United States)

2015-03-10

We present N-body simulations of resonant planets with inclined orbits that show chaotically evolving eccentricities and inclinations that can persist for at least 10 Gyr. A wide range of behavior is possible, from fast, low amplitude variations to systems in which eccentricities reach 0.9999 and inclinations 179.°9. While the orbital elements evolve chaotically, at least one resonant argument always librates. We show that the HD 73526, HD 45364, and HD 60532 systems may be in chaotically evolving resonances. Chaotic evolution is apparent in the 2:1, 3:1, and 3:2 resonances, and for planetary masses from lunar- to Jupiter-mass. In some cases, orbital disruption occurs after several gigayears, implying the mechanism is not rigorously stable, just long-lived relative to the main sequence lifetimes of solar-type stars. Planet-planet scattering appears to yield planets in inclined resonances that evolve chaotically in about 0.5% of cases. These results suggest that (1) approximate methods for identifying unstable orbital architectures may have limited applicability, (2) the observed close-in exoplanets may be produced during epochs of high eccentricit induced by inclined resonances, (3) those exoplanets' orbital planes may be misaligned with the host star's spin axis, (4) systems with resonances may be systematically younger than those without, (5) the distribution of period ratios of adjacent planets detected via transit may be skewed due to inclined resonances, and (6) potentially habitable planets may have dramatically different climatic evolution than Earth. The Gaia spacecraft is capable of discovering giant planets in these types of orbits.

LONG-LIVED CHAOTIC ORBITAL EVOLUTION OF EXOPLANETS IN MEAN MOTION RESONANCES WITH MUTUAL INCLINATIONS

International Nuclear Information System (INIS)

Barnes, Rory; Deitrick, Russell; Quinn, Thomas R.; Greenberg, Richard; Raymond, Sean N.

2015-01-01

We present N-body simulations of resonant planets with inclined orbits that show chaotically evolving eccentricities and inclinations that can persist for at least 10 Gyr. A wide range of behavior is possible, from fast, low amplitude variations to systems in which eccentricities reach 0.9999 and inclinations 179.°9. While the orbital elements evolve chaotically, at least one resonant argument always librates. We show that the HD 73526, HD 45364, and HD 60532 systems may be in chaotically evolving resonances. Chaotic evolution is apparent in the 2:1, 3:1, and 3:2 resonances, and for planetary masses from lunar- to Jupiter-mass. In some cases, orbital disruption occurs after several gigayears, implying the mechanism is not rigorously stable, just long-lived relative to the main sequence lifetimes of solar-type stars. Planet-planet scattering appears to yield planets in inclined resonances that evolve chaotically in about 0.5% of cases. These results suggest that (1) approximate methods for identifying unstable orbital architectures may have limited applicability, (2) the observed close-in exoplanets may be produced during epochs of high eccentricit induced by inclined resonances, (3) those exoplanets' orbital planes may be misaligned with the host star's spin axis, (4) systems with resonances may be systematically younger than those without, (5) the distribution of period ratios of adjacent planets detected via transit may be skewed due to inclined resonances, and (6) potentially habitable planets may have dramatically different climatic evolution than Earth. The Gaia spacecraft is capable of discovering giant planets in these types of orbits

The Complete Chloroplast and Mitochondrial Genome Sequences of Boea hygrometrica: Insights into the Evolution of Plant Organellar Genomes

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Wang, Xumin; Deng, Xin; Zhang, Xiaowei; Hu, Songnian; Yu, Jun

2012-01-01

The complete nucleotide sequences of the chloroplast (cp) and mitochondrial (mt) genomes of resurrection plant Boea hygrometrica (Bh, Gesneriaceae) have been determined with the lengths of 153,493 bp and 510,519 bp, respectively. The smaller chloroplast genome contains more genes (147) with a 72% coding sequence, and the larger mitochondrial genome have less genes (65) with a coding faction of 12%. Similar to other seed plants, the Bh cp genome has a typical quadripartite organization with a conserved gene in each region. The Bh mt genome has three recombinant sequence repeats of 222 bp, 843 bp, and 1474 bp in length, which divide the genome into a single master circle (MC) and four isomeric molecules. Compared to other angiosperms, one remarkable feature of the Bh mt genome is the frequent transfer of genetic material from the cp genome during recent Bh evolution. We also analyzed organellar genome evolution in general regarding genome features as well as compositional dynamics of sequence and gene structure/organization, providing clues for the understanding of the evolution of organellar genomes in plants. The cp-derived sequences including tRNAs found in angiosperm mt genomes support the conclusion that frequent gene transfer events may have begun early in the land plant lineage. PMID:22291979

Role of erosion and isostasy in the Cordillera Blanca uplift: Insights from landscape evolution modeling (northern Peru, Andes)

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Margirier, Audrey; Braun, Jean; Robert, Xavier; Audin, Laurence

2018-03-01

The processes driving uplift and exhumation of the highest Peruvian peaks (the Cordillera Blanca) are not well understood. Uplift and exhumation seem closely linked to the formation and movement on the Cordillera Blanca normal fault (CBNF) that delimits and shapes the western flank of the Cordillera Blanca. Several models have been proposed to explain the presence of this major normal fault in a compressional setting, but the CBNF and the Cordillera Blanca recent rapid uplift remain enigmatic. Whereas the Cordillera Blanca morphology demonstrates important erosion and thus a significant mass of rocks removal, the impact of erosion and isostasy on the evolution of the Cordillera Blanca uplift rates has never been explored. We address the role of erosion and associated flexural rebound in the uplift and exhumation of the Cordillera Blanca with numerical modeling of landscape evolution. We perform inversions of the broad features of the present-day topography, total exhumation and thermochronological data using a landscape evolution model (FastScape) to provide constraints on the erosion efficiency factor, the uplift rate and the temperature gradient. Our results evidence the not negligible contribution of erosion and associated flexural rebound to the uplift of the Cordillera Blanca and allow us to question the models previously proposed for the formation of the CBNF.

Effect of nuclear reaction rates on primordial abundances

International Nuclear Information System (INIS)

Mishra, Abhishek; Basu, D.N.

2011-01-01

The theoretical predictions of the primordial abundances of elements in the big-bang nucleosynthesis (BBN) are dominated by uncertainties in the input nuclear reaction rates. The effect of modifying these reaction rates on light element abundance yields in BBN by replacing the thirty-five reaction rates out of the existing eighty-eight has been investigated. Also the study have been taken of these yields as functions of evolution time or temperature. Here it has been found that using these new reaction rates results in only a little increase in helium mass fraction over that obtained previously in BBN calculations. This allows insights into the role of the nuclear reaction rates in the setting of the neutron-to-proton ratio during the BBN epoch. We observe that most of these nuclear reactions have minimal effect on the standard BBN abundance yields of 6 Li and 7 Li

The Independent Evolution Method Is Not a Viable Phylogenetic Comparative Method.

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Randi H Griffin

Full Text Available Phylogenetic comparative methods (PCMs use data on species traits and phylogenetic relationships to shed light on evolutionary questions. Recently, Smaers and Vinicius suggested a new PCM, Independent Evolution (IE, which purportedly employs a novel model of evolution based on Felsenstein's Adaptive Peak Model. The authors found that IE improves upon previous PCMs by producing more accurate estimates of ancestral states, as well as separate estimates of evolutionary rates for each branch of a phylogenetic tree. Here, we document substantial theoretical and computational issues with IE. When data are simulated under a simple Brownian motion model of evolution, IE produces severely biased estimates of ancestral states and changes along individual branches. We show that these branch-specific changes are essentially ancestor-descendant or "directional" contrasts, and draw parallels between IE and previous PCMs such as "minimum evolution". Additionally, while comparisons of branch-specific changes between variables have been interpreted as reflecting the relative strength of selection on those traits, we demonstrate through simulations that regressing IE estimated branch-specific changes against one another gives a biased estimate of the scaling relationship between these variables, and provides no advantages or insights beyond established PCMs such as phylogenetically independent contrasts. In light of our findings, we discuss the results of previous papers that employed IE. We conclude that Independent Evolution is not a viable PCM, and should not be used in comparative analyses.

Young solar-type stars evolution: the lithium and seismology contributions

International Nuclear Information System (INIS)

Piau, Laurent Eric

2001-01-01

This PhD thesis is devoted to young low-mass stars. We modeled many of them since their formation until the solar age covering the range between 0.65 and 1.4 solar masses and metallicity values ranging from -0.1 to 0.1 dex. The theoretical computations are related to observations in nearby open-clusters: Hyades, Pleiades... This comparison demonstrates that the lithium evolution is still poorly understood in such stars. In stellar interiors, this nuclide is destroyed by nuclear processes at low temperatures. Its surface abundance evolution traduces mixing phenomena between surface and deeper layers and therefore allows a direct insight into stellar structure and evolution. Both of which depend on microscopic and macroscopic physical phenomena whose effects we systematically examine. As regards microphysics we mainly concentrate upon changes in metallicity, in distribution among metals and their consequences on stellar opacity. We also address atmospheric models while the star still lies close to its Hayashi track. Accretion and convective parameters are the macroscopic phenomena we address during pre-main sequence. The rotational effects are considered along the entire evolution including the much realistic rotation laws. The last part of this PhD thesis makes use of seismology. Today this Discipline allows direct probing of the solar internal structure and motions. Its future application in the realm of stars will substantially improve their understanding. We derive here some relevant seismic variables for the understanding of stellar evolution. Then we show how this powerful tool permits to determine fundamental stellar parameters such as the mass or the helium fraction. (author) [fr

Evolution of stellar systems

International Nuclear Information System (INIS)

Vader, P.

1981-01-01

The stellar systems of which the evolution will be considered in this thesis, are either galaxies, which contain about 10 11 stars, or binary systems, which consist of only two stars. It is seen that binary systems can give us some insight into the relative age of the nucleus of M31. The positive correlation between the metal content of a galaxy and its mass, first noted for elliptical galaxies, seems to be a general property of galaxies of all types. The observed increase of metallicity with galaxy mass is too large to be accounted for by differences in the evolutionary stage of galaxies. To explain the observed correlation it is proposed that a relatively larger proportion of massive stars is formed in more massive galaxies. The physical basis is that the formation of massive stars seems to be tied to the enhanced gas-dynamical activity in more massive galaxies. A specific aspect of the production of heavy elements by massive stars is investigated in some detail. In 1979 a cluster of 18 point X-ray sources within 400 pc of the centre of M31 was detected with the Einstein satellite. This is a remarkable result since no equivalent of this cluster has been observed in the nucleus of our own Galaxy, which otherwise is very similar to that of M31. An explanation for this phenomenon is proposed, suggesting that X-ray binaries are the products of the long-term evolution of nova systems. (Auth.)

Epoch of reionization 21 cm forecasting from MCMC-constrained semi-numerical models

Science.gov (United States)

Hassan, Sultan; Davé, Romeel; Finlator, Kristian; Santos, Mario G.

2017-06-01

The recent low value of Planck Collaboration XLVII integrated optical depth to Thomson scattering suggests that the reionization occurred fairly suddenly, disfavouring extended reionization scenarios. This will have a significant impact on the 21 cm power spectrum. Using a semi-numerical framework, we improve our model from instantaneous to include time-integrated ionization and recombination effects, and find that this leads to more sudden reionization. It also yields larger H II bubbles that lead to an order of magnitude more 21 cm power on large scales, while suppressing the small-scale ionization power. Local fluctuations in the neutral hydrogen density play the dominant role in boosting the 21 cm power spectrum on large scales, while recombinations are subdominant. We use a Monte Carlo Markov chain approach to constrain our model to observations of the star formation rate functions at z = 6, 7, 8 from Bouwens et al., the Planck Collaboration XLVII optical depth measurements and the Becker & Bolton ionizing emissivity data at z ˜ 5. We then use this constrained model to perform 21 cm forecasting for Low Frequency Array, Hydrogen Epoch of Reionization Array and Square Kilometre Array in order to determine how well such data can characterize the sources driving reionization. We find that the Mock 21 cm power spectrum alone can somewhat constrain the halo mass dependence of ionizing sources, the photon escape fraction and ionizing amplitude, but combining the Mock 21 cm data with other current observations enables us to separately constrain all these parameters. Our framework illustrates how the future 21 cm data can play a key role in understanding the sources and topology of reionization as observations improve.

IMAGING THE EPOCH OF REIONIZATION: LIMITATIONS FROM FOREGROUND CONFUSION AND IMAGING ALGORITHMS

International Nuclear Information System (INIS)

Vedantham, Harish; Udaya Shankar, N.; Subrahmanyan, Ravi

2012-01-01

Tomography of redshifted 21 cm transition from neutral hydrogen using Fourier synthesis telescopes is a promising tool to study the Epoch of Reionization (EoR). Limiting the confusion from Galactic and extragalactic foregrounds is critical to the success of these telescopes. The instrumental response or the point-spread function (PSF) of such telescopes is inherently three dimensional with frequency mapping to the line-of-sight (LOS) distance. EoR signals will necessarily have to be detected in data where continuum confusion persists; therefore, it is important that the PSF has acceptable frequency structure so that the residual foreground does not confuse the EoR signature. This paper aims to understand the three-dimensional PSF and foreground contamination in the same framework. We develop a formalism to estimate the foreground contamination along frequency, or equivalently LOS dimension, and establish a relationship between foreground contamination in the image plane and visibility weights on the Fourier plane. We identify two dominant sources of LOS foreground contamination—'PSF contamination' and 'gridding contamination'. We show that PSF contamination is localized in LOS wavenumber space, beyond which there potentially exists an 'EoR window' with negligible foreground contamination where we may focus our efforts to detect EoR. PSF contamination in this window may be substantially reduced by judicious choice of a frequency window function. Gridding and imaging algorithms create additional gridding contamination and we propose a new imaging algorithm using the Chirp Z Transform that significantly reduces this contamination. Finally, we demonstrate the analytical relationships and the merit of the new imaging algorithm for the case of imaging with the Murchison Widefield Array.

Field Flows of Dark Energy

Energy Technology Data Exchange (ETDEWEB)

Cahn, Robert N.; de Putter, Roland; Linder, Eric V.

2008-07-08

Scalar field dark energy evolving from a long radiation- or matter-dominated epoch has characteristic dynamics. While slow-roll approximations are invalid, a well defined field expansion captures the key aspects of the dark energy evolution during much of the matter-dominated epoch. Since this behavior is determined, it is not faithfully represented if priors for dynamical quantities are chosen at random. We demonstrate these features for both thawing and freezing fields, and for some modified gravity models, and unify several special cases in the literature.

The Evolution of Community Self-Organization in Interaction With Government Institutions: Cross-Case Insights From Three Countries

NARCIS (Netherlands)

J. Edelenbos (Jurian); I.F. van Meerkerk (Ingmar); Schenk, T. (Todd)

2018-01-01

textabstractThis article deals with the evolution of community self-organization in public administration. Within the literature of interactive governance, increasing attention is being paid to how communities take initiative in dealing with societal issues. However, we know little about the factors

Modeling evolution of crosstalk in noisy signal transduction networks

Science.gov (United States)

Tareen, Ammar; Wingreen, Ned S.; Mukhopadhyay, Ranjan

2018-02-01

Signal transduction networks can form highly interconnected systems within cells due to crosstalk between constituent pathways. To better understand the evolutionary design principles underlying such networks, we study the evolution of crosstalk for two parallel signaling pathways that arise via gene duplication. We use a sequence-based evolutionary algorithm and evolve the network based on two physically motivated fitness functions related to information transmission. We find that one fitness function leads to a high degree of crosstalk while the other leads to pathway specificity. Our results offer insights on the relationship between network architecture and information transmission for noisy biomolecular networks.

Dynamics of large-scale solar wind streams obtained by the double superposed epoch analysis

Science.gov (United States)

Yermolaev, Yu. I.; Lodkina, I. G.; Nikolaeva, N. S.; Yermolaev, M. Yu.

2015-09-01

Using the OMNI data for period 1976-2000, we investigate the temporal profiles of 20 plasma and field parameters in the disturbed large-scale types of solar wind (SW): corotating interaction regions (CIR), interplanetary coronal mass ejections (ICME) (both magnetic cloud (MC) and Ejecta), and Sheath as well as the interplanetary shock (IS). To take into account the different durations of SW types, we use the double superposed epoch analysis (DSEA) method: rescaling the duration of the interval for all types in such a manner that, respectively, beginning and end for all intervals of selected type coincide. As the analyzed SW types can interact with each other and change parameters as a result of such interaction, we investigate separately eights sequences of SW types: (1) CIR, (2) IS/CIR, (3) Ejecta, (4) Sheath/Ejecta, (5) IS/Sheath/Ejecta, (6) MC, (7) Sheath/MC, and (8) IS/Sheath/MC. The main conclusion is that the behavior of parameters in Sheath and in CIR are very similar both qualitatively and quantitatively. Both the high-speed stream (HSS) and the fast ICME play a role of pistons which push the plasma located ahead them. The increase of speed in HSS and ICME leads at first to formation of compression regions (CIR and Sheath, respectively) and then to IS. The occurrence of compression regions and IS increases the probability of growth of magnetospheric activity.

Diverse properties of interstellar medium embedding gamma-ray bursts at the epoch of reionization

International Nuclear Information System (INIS)

Cen, Renyue; Kimm, Taysun

2014-01-01

Analysis is performed on ultra-high-resolution large-scale cosmological radiation-hydrodynamic simulations to quantify, for the first time, the physical environment of long-duration gamma-ray bursts (GRBs) at the epoch of reionization. We find that, on parsec scales, 13% of GRBs remain in high-density (≥10 4 cm –3 ) low-temperature star-forming regions, whereas 87% of GRBs occur in low-density (∼10 –2.5 cm –3 ) high-temperature regions heated by supernovae. More importantly, the spectral properties of GRB afterglows, such as the neutral hydrogen column density, total hydrogen column density, dust column density, gas temperature, and metallicity of intervening absorbers, vary strongly from sight line to sight line. Although our model explains extant limited observationally inferred values with respect to circumburst density, metallicity, column density, and dust properties, a substantially larger sample of high-z GRB afterglows would be required to facilitate a statistically solid test of the model. Our findings indicate that any attempt to infer the physical properties (such as metallicity) of the interstellar medium (ISM) of the host galaxy based on a very small number (usually one) of sight lines would be precarious. Utilizing high-z GRBs to probe the ISM and intergalactic medium should be undertaken properly, taking into consideration the physical diversities of the ISM.

LCROSS Impact Conditions and Ejecta Evolution: Insight from Experiments

Science.gov (United States)

Hermalyn, B.; Schultz, P. H.; Colaprete, A.

2009-12-01

from these experiments is a factor of ~10 less than predicted by methods above (Korycansky, et al 2009). Analysis of the LCROSS ejecta emergence and evolution, when compared with scaled experimental results, will provide an understanding of the impact conditions as well as constraints on the properties of the regolith.